Guide to the Human Genome
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Search of human proteins with 21704283

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21704283 junctophilin 3 [Homo sapiens]
         (748 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21704283 junctophilin 3 [Homo sapiens]                            1517   0.0  
gi|21735575 junctophilin 1 [Homo sapiens]                             650   0.0  
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]                   596   e-170
gi|225690502 junctophilin 4 [Homo sapiens]                            460   e-129
gi|225690500 junctophilin 4 [Homo sapiens]                            460   e-129
gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]                   252   1e-66
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]            78   3e-14
gi|157502187 radial spoke head 10 homolog B [Homo sapiens]             78   3e-14
gi|18254456 testis-specific gene A2 [Homo sapiens]                     77   6e-14
gi|50355990 MORN repeat containing 3 [Homo sapiens]                    77   8e-14
gi|13376267 MORN repeat containing 1 [Homo sapiens]                    72   2e-12
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]              68   4e-11
gi|40316935 alsin isoform 1 [Homo sapiens]                             67   5e-11
gi|149999376 MORN repeat containing 4 [Homo sapiens]                   64   5e-10
gi|30520314 MORN repeat containing 4 [Homo sapiens]                    64   5e-10
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    44   5e-04
gi|224282170 MORN repeat containing 2 [Homo sapiens]                   44   5e-04
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             43   0.001
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 42   0.002
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 42   0.002
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  42   0.002
gi|56699482 hypothetical protein LOC25940 [Homo sapiens]               41   0.005
gi|188536004 zinc finger protein 469 [Homo sapiens]                    40   0.008
gi|75750529 ankyrin repeat and MYND domain containing 1 isoform ...    40   0.008
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b...    39   0.023
gi|20357556 cortactin isoform b [Homo sapiens]                         39   0.023
gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ...    38   0.030
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    38   0.039
gi|223278407 MORN repeat containing 5 [Homo sapiens]                   37   0.067
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         37   0.087

>gi|21704283 junctophilin 3 [Homo sapiens]
          Length = 748

 Score = 1517 bits (3927), Expect = 0.0
 Identities = 748/748 (100%), Positives = 748/748 (100%)

Query: 1   MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT 60
           MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT
Sbjct: 1   MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT 60

Query: 61  YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG 120
           YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG
Sbjct: 61  YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG 120

Query: 121 TETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPD 180
           TETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPD
Sbjct: 121 TETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPD 180

Query: 181 ASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSK 240
           ASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSK
Sbjct: 181 ASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSK 240

Query: 241 QSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGF 300
           QSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGF
Sbjct: 241 QSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGF 300

Query: 301 GVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIR 360
           GVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIR
Sbjct: 301 GVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIR 360

Query: 361 EKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFS 420
           EKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFS
Sbjct: 361 EKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFS 420

Query: 421 PSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSF 480
           PSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSF
Sbjct: 421 PSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSF 480

Query: 481 PTSPAATPPPAPAARNKVAHFSRQVSVDEERGGDIQMLLEGRAGDCARSSWGEEQAGGSR 540
           PTSPAATPPPAPAARNKVAHFSRQVSVDEERGGDIQMLLEGRAGDCARSSWGEEQAGGSR
Sbjct: 481 PTSPAATPPPAPAARNKVAHFSRQVSVDEERGGDIQMLLEGRAGDCARSSWGEEQAGGSR 540

Query: 541 GVRSGALRGGLLVDDFRTRGSGRKQPGNPKPRERRTESPPVFTWTSHHRASNHSPGGSRL 600
           GVRSGALRGGLLVDDFRTRGSGRKQPGNPKPRERRTESPPVFTWTSHHRASNHSPGGSRL
Sbjct: 541 GVRSGALRGGLLVDDFRTRGSGRKQPGNPKPRERRTESPPVFTWTSHHRASNHSPGGSRL 600

Query: 601 LELQEEKLSNYRMEMKPLLRMETHPQKRRYSKGGACRGLGDDHRPEDRGFGVQRLRSKAQ 660
           LELQEEKLSNYRMEMKPLLRMETHPQKRRYSKGGACRGLGDDHRPEDRGFGVQRLRSKAQ
Sbjct: 601 LELQEEKLSNYRMEMKPLLRMETHPQKRRYSKGGACRGLGDDHRPEDRGFGVQRLRSKAQ 660

Query: 661 NKENFRPASSAEPAVQKLASLRLGGAEPRLLRWDLTFSPPQKSLPVALESDEENGDELKS 720
           NKENFRPASSAEPAVQKLASLRLGGAEPRLLRWDLTFSPPQKSLPVALESDEENGDELKS
Sbjct: 661 NKENFRPASSAEPAVQKLASLRLGGAEPRLLRWDLTFSPPQKSLPVALESDEENGDELKS 720

Query: 721 STGSAPILVVMVILLNIGVAILFINFFI 748
           STGSAPILVVMVILLNIGVAILFINFFI
Sbjct: 721 STGSAPILVVMVILLNIGVAILFINFFI 748


>gi|21735575 junctophilin 1 [Homo sapiens]
          Length = 661

 Score =  650 bits (1677), Expect = 0.0
 Identities = 323/493 (65%), Positives = 387/493 (78%), Gaps = 17/493 (3%)

Query: 3   SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQ 62
           +GGRF+FDDGG+YCGGWE+GKAHGHG+CTGPKGQGEY+GSWSHGFEV+G YTWPSGNTYQ
Sbjct: 2   TGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQ 61

Query: 63  GTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTE 122
           G WAQGKRHG+G+E+KGKW+Y+GEW+HGFKGRYGVR+     A+YEGTWSNGLQDGYG E
Sbjct: 62  GYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVE 121

Query: 123 TYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPDAS 182
           TY DGGTYQGQW GGMR GYGVRQSVPYGMA VIRSPLRTS+ SLRSE +NG+ LH  A 
Sbjct: 122 TYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA- 180

Query: 183 PAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRR-SLLSGLKLRKSESKSSLASQRSKQ 241
            A A SPA +RGGFVL  H+D+E+   KK GLFRR SLL  +KLRKSESKSS++   SK+
Sbjct: 181 -AAADSPAGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSIS---SKR 236

Query: 242 SSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFG 301
           SS RS+A MS +SS  SD +STIS G+ + +   +ED +DATTTETY+GEWKNDKR+GFG
Sbjct: 237 SSVRSDAAMSRISS--SDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFG 294

Query: 302 VSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIRE 361
           VS+RS+G+KYEGEWA+N+RHGYGC  FPDG+KEEGKYK NILV G RK LIP+R +K RE
Sbjct: 295 VSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRHTKTRE 354

Query: 362 KVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSP 421
           KVDRA+E A+RAA +A+ K EIA SRT+H+RAKA+AA  AA  A++E  IAR  A+E SP
Sbjct: 355 KVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSP 414

Query: 422 SFQHRENGLEYQRPKRQTSCD----DIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPL 477
            F   + G +Y + + Q   D      E +    P  +ESP  YRKGTTP   +P+ SP 
Sbjct: 415 DFY--QPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTP-PRSPEASPK 471

Query: 478 QSFPTSPAATPPP 490
            S   SPA++P P
Sbjct: 472 HSH--SPASSPKP 482



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 19/53 (35%), Positives = 34/53 (64%), Gaps = 5/53 (9%)

Query: 699 PPQKSLPVALESDEENGD-----ELKSSTGSAPILVVMVILLNIGVAILFINF 746
           P  K   +A+  +  + D     E ++++G   I++V+V+LLNIG+AILF++F
Sbjct: 607 PKAKKSELAIPKNPASNDSCPALEKEANSGPNSIMIVLVMLLNIGLAILFVHF 659


>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
          Length = 696

 Score =  596 bits (1536), Expect = e-170
 Identities = 366/779 (46%), Positives = 472/779 (60%), Gaps = 123/779 (15%)

Query: 3   SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQ 62
           SGGRF+FDDGG+YCGGWE GKAHGHG+CTGPKGQGEY+GSW+ GFEV GVYTWPSGNT++
Sbjct: 2   SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFE 61

Query: 63  GTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTE 122
           G W+QGKRHG+G+E+KG+W+YKGEWTHGFKGRYG+R+ + +GAKYEGTW+NGLQDGYGTE
Sbjct: 62  GYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTE 121

Query: 123 TYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPD-- 180
           TY+DGGTYQGQ+  GMR GYGVRQSVPYGMA V+RSPLRTS++SLRSEH+NGT + PD  
Sbjct: 122 TYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGT-VAPDSP 180

Query: 181 ASPAVAG----SPAVSRGGFV--LVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSL 234
           ASPA  G    SPA+ RGGF   L+A++++     K  GLF+R  L G KLR++ES++S+
Sbjct: 181 ASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGLFQRGALLG-KLRRAESRTSV 239

Query: 235 ASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEA---ELAVIEDDIDATTTETYVGE 291
            SQRS+ S  +S+     +SS ASD  ST SLGEA     E A  E DIDATTTETY+GE
Sbjct: 240 GSQRSRVSFLKSD-----LSSGASDAASTASLGEAAEGADEAAPFEADIDATTTETYMGE 294

Query: 292 WKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNL 351
           WKNDKRSGFGVS+RS GL+YEGEW  N RHGYGC T PDG +EEGKY+ N+LV   ++ +
Sbjct: 295 WKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRRM 354

Query: 352 IPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARI 411
           + L+++K+R+KV+ +VE A+RAA IA+QKAEIAASRTSH++AKAEAA  AA  A +E+ I
Sbjct: 355 LQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNI 414

Query: 412 ARITAKEFSPSFQHRENGLEYQRPK-RQTSCDDIEVL---------STGTPL-QQESPEL 460
           AR  A+E +P F   + G EYQ+ +  Q   ++ E L         + G P   +ESP+L
Sbjct: 415 ARTLARELAPDFY--QPGPEYQKRRLLQEILENSESLLEPPDRGAGAAGLPQPPRESPQL 472

Query: 461 YRKGT-TPSDLTPDDSPLQSFPTSPAATPPPAPAARNKVAHFSRQVSVDEERGGDIQMLL 519
           + + T  P   +P          SPA TPP     R  V+                    
Sbjct: 473 HERETPRPEGGSP----------SPAGTPPQPKRPRPGVS-------------------- 502

Query: 520 EGRAGDCARSSWGEEQAG-GSRGVRSGALRGGLLVDDFRTRGSGRKQPGNPKPRERRTES 578
             + G  +  +W  E +G GSR V               + G+GR+ P  P       E 
Sbjct: 503 --KDGLLSPGAWNGEPSGEGSRSVTP-------------SEGAGRRSPARPATERMAIE- 546

Query: 579 PPVFTWTSHHRASNHSPGGSRLLELQEEKLSNYRMEMKPLLRMETHPQKRRYSKGGACRG 638
                      A    P  SR     E +++ Y+      +R  T P+   +        
Sbjct: 547 -----------ALQAPPAPSR-----EPEVALYQGYHSYAVR-TTPPEPPPF-------- 581

Query: 639 LGDDHRPEDRGFGVQRLRSKAQNKENFRPA-SSAEPAVQKLASLR----LGGAEPRLL-- 691
              + +PE    G +   S         P     EPA +  A L     +  AEPR    
Sbjct: 582 ---EDQPEPEVSGSESAPSSPATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKAR 638

Query: 692 ---RWDLTFSPPQKSL--PVALESDEENGDELKSSTGSAPILVVMVILLNIGVAILFIN 745
                 LT +  +K      AL ++ E   E   +T    IL+ MVILLNIG+AILF++
Sbjct: 639 KTEARGLTKAGAKKKARKEAALAAEAEVEVEEVPNT----ILICMVILLNIGLAILFVH 693


>gi|225690502 junctophilin 4 [Homo sapiens]
          Length = 628

 Score =  460 bits (1183), Expect = e-129
 Identities = 269/532 (50%), Positives = 341/532 (64%), Gaps = 50/532 (9%)

Query: 1   MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT 60
           MS GG+F+FDDGG Y GGWE G+AHG+GVCTGP  QGEY+G W+HGFE LGV+T P G++
Sbjct: 1   MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS 60

Query: 61  YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG 120
           YQG W QGKR G+G+E K +W Y+GEW  G KGR GV E   +G +Y G W +G QDGYG
Sbjct: 61  YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESV-SGLRYAGLWKDGFQDGYG 119

Query: 121 TETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPD 180
           TETYSDGGTYQGQW  G R GYGVRQSVPY  AA++RSP RTS++S  S+    T   P 
Sbjct: 120 TETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPP--TPPPPL 177

Query: 181 ASPA-VAGSPAV-SRGGFVLVAHSDSEILKSKKK-----GLFRRS-LLSGLKLRKSESKS 232
             P    GSPA  SRGGFVL    D++   S+K+     G FRRS LLSG  LR    +S
Sbjct: 178 PLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSG--LRAGGRRS 235

Query: 233 SLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEW 292
           SL    SK+ S RSE   S V ST     S  S   A A  A+IE     + TE Y GEW
Sbjct: 236 SLG---SKRGSLRSEVS-SEVGSTGPP-GSEASGPPAAAPPALIE----GSATEVYAGEW 286

Query: 293 KNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILV-GGKRKNL 351
           + D+RSGFGVSQRS+GL+YEGEW  NRRHGYG  T PDG++EEGKYK+N LV GG+ ++L
Sbjct: 287 RADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSL 346

Query: 352 IP--LRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEA 409
           +P  LR  K++EKVDRAVE A RA + A+Q+ EIAA+R + +  KA AA + A+KA E A
Sbjct: 347 LPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAA 406

Query: 410 RIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSD 469
           R+A++ A++  P  +        +RP++ +   D E      PL ++SP +Y  G TPS+
Sbjct: 407 RMAKLIAQDLQPMLE-----APGRRPRQDSEGSDTE------PLDEDSPGVYENGLTPSE 455

Query: 470 LTPDDSPLQSFPTSPAATPPP--APAARNKV------AHFSRQVSVDEERGG 513
            +P+       P+SPA++  P   PA R+ +        FS   +  EE GG
Sbjct: 456 GSPE------LPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGG 501


>gi|225690500 junctophilin 4 [Homo sapiens]
          Length = 628

 Score =  460 bits (1183), Expect = e-129
 Identities = 269/532 (50%), Positives = 341/532 (64%), Gaps = 50/532 (9%)

Query: 1   MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT 60
           MS GG+F+FDDGG Y GGWE G+AHG+GVCTGP  QGEY+G W+HGFE LGV+T P G++
Sbjct: 1   MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS 60

Query: 61  YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG 120
           YQG W QGKR G+G+E K +W Y+GEW  G KGR GV E   +G +Y G W +G QDGYG
Sbjct: 61  YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESV-SGLRYAGLWKDGFQDGYG 119

Query: 121 TETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPD 180
           TETYSDGGTYQGQW  G R GYGVRQSVPY  AA++RSP RTS++S  S+    T   P 
Sbjct: 120 TETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPP--TPPPPL 177

Query: 181 ASPA-VAGSPAV-SRGGFVLVAHSDSEILKSKKK-----GLFRRS-LLSGLKLRKSESKS 232
             P    GSPA  SRGGFVL    D++   S+K+     G FRRS LLSG  LR    +S
Sbjct: 178 PLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSG--LRAGGRRS 235

Query: 233 SLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEW 292
           SL    SK+ S RSE   S V ST     S  S   A A  A+IE     + TE Y GEW
Sbjct: 236 SLG---SKRGSLRSEVS-SEVGSTGPP-GSEASGPPAAAPPALIE----GSATEVYAGEW 286

Query: 293 KNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILV-GGKRKNL 351
           + D+RSGFGVSQRS+GL+YEGEW  NRRHGYG  T PDG++EEGKYK+N LV GG+ ++L
Sbjct: 287 RADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSL 346

Query: 352 IP--LRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEA 409
           +P  LR  K++EKVDRAVE A RA + A+Q+ EIAA+R + +  KA AA + A+KA E A
Sbjct: 347 LPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAA 406

Query: 410 RIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSD 469
           R+A++ A++  P  +        +RP++ +   D E      PL ++SP +Y  G TPS+
Sbjct: 407 RMAKLIAQDLQPMLE-----APGRRPRQDSEGSDTE------PLDEDSPGVYENGLTPSE 455

Query: 470 LTPDDSPLQSFPTSPAATPPP--APAARNKV------AHFSRQVSVDEERGG 513
            +P+       P+SPA++  P   PA R+ +        FS   +  EE GG
Sbjct: 456 GSPE------LPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGG 501


>gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]
          Length = 129

 Score =  252 bits (643), Expect = 1e-66
 Identities = 101/126 (80%), Positives = 120/126 (95%)

Query: 3   SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQ 62
           SGGRF+FDDGG+YCGGWE GKAHGHG+CTGPKGQGEY+GSW+ GFEV GVYTWPSGNT++
Sbjct: 2   SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFE 61

Query: 63  GTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTE 122
           G W+QGKRHG+G+E+KG+W+YKGEWTHGFKGRYG+R+ + +GAKYEGTW+NGLQDGYGTE
Sbjct: 62  GYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTE 121

Query: 123 TYSDGG 128
           TY+DGG
Sbjct: 122 TYADGG 127



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)

Query: 288 YVGEWKNDKRSGFGVSQRSD-GLKYEGEWASNRRHGYGCMTFPDG 331
           Y GEW +  +  +G+ Q S  G KYEG W +  + GYG  T+ DG
Sbjct: 82  YKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADG 126


>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
          Length = 870

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 46/141 (32%), Positives = 65/141 (46%), Gaps = 9/141 (6%)

Query: 9   FDDGGSYCGGWEDGKAHGHGV---CTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTW 65
           F  G +Y G + +G  HG G      G K +G++  +        GVYTWP G+ Y+G  
Sbjct: 103 FQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH---GVYTWPDGSMYEGEV 159

Query: 66  AQGKRHGIGLE--SKGKWVYKGEWTHGFK-GRYGVRECAGNGAKYEGTWSNGLQDGYGTE 122
             G R+G G+   S     Y G W +G + G+  +         YEG W   ++ G+G  
Sbjct: 160 VNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIR 219

Query: 123 TYSDGGTYQGQWVGGMRQGYG 143
            Y  G  Y+GQW   MR G G
Sbjct: 220 CYKSGNIYEGQWEDNMRHGEG 240



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 44/146 (30%), Positives = 62/146 (42%), Gaps = 19/146 (13%)

Query: 14  SYCGGWEDGKAHGHG-VCTGPKGQGEYTGSWSHGFEV-LGVYTWPSGNTYQGTWAQGKRH 71
           SY G W +GK HG G +    +G   Y G W    +   G+  + SGN Y+G W    RH
Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237

Query: 72  GIGLESKGKWV-----YKGEWTHGFKGRYGVRECAGNGAK---------YEGTWSNGLQD 117
           G   E + +W+     Y G W  G +  +G         +         Y G + NG + 
Sbjct: 238 G---EGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294

Query: 118 GYGTETYSDGGTYQGQWVGGMRQGYG 143
           G G   Y+ G  Y G+WV   + G G
Sbjct: 295 GRGKFYYASGAMYDGEWVSNKKHGMG 320



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 54/183 (29%), Positives = 73/183 (39%), Gaps = 43/183 (23%)

Query: 1   MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKG---QGEYTGSWSHGFEVLGVYTWPS 57
           M   G + + DG  Y G +       HGV T P G   +GE      +GF +    T P 
Sbjct: 118 MHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPV 177

Query: 58  GNTYQGTWAQGKRHGIG---LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSN- 113
             +Y G W  GKRHG G      +G   Y+G+W    K  +G+R C  +G  YEG W + 
Sbjct: 178 --SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIR-CYKSGNIYEGQWEDN 234

Query: 114 -----------------------GLQDGYGTET----------YSDGGTYQGQWVGGMRQ 140
                                  G+Q+G+GT T          Y     Y G++V G R 
Sbjct: 235 MRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294

Query: 141 GYG 143
           G G
Sbjct: 295 GRG 297



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 23/58 (39%), Positives = 34/58 (58%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
           Y+GE+ N  R G G    + G  Y+GEW SN++HG G +TF +G   EG +  + + G
Sbjct: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)

Query: 60  TYQGTWAQGKRHGIGLES-KGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDG 118
           +Y+G   +G   G G  + +G   Y+G ++ G     G    A +G KYEG +   +   
Sbjct: 85  SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWA-DGLKYEGDFVKNVPMN 143

Query: 119 YGTETYSDGGTYQGQWVGGMRQGYGV 144
           +G  T+ DG  Y+G+ V GMR G+G+
Sbjct: 144 HGVYTWPDGSMYEGEVVNGMRNGFGM 169



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 282 ATTTETYVGEWKNDKRSGFG-VSQRSDGLK-YEGEWASNRRHGYGCMTFPDGTKEEGKYK 339
           +T   +Y+G W N KR G G +    +G   YEG+W  N + G+G   +  G   EG+++
Sbjct: 173 STQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWE 232

Query: 340 QNILVGGKR 348
            N+  G  R
Sbjct: 233 DNMRHGEGR 241



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKE-EGKYKQNILVG 345
           Y G+W  + + G+G+     G  YEG+W  N RHG G M +    +E  G++++ I  G
Sbjct: 204 YEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNG 262



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 20/51 (39%), Positives = 28/51 (54%)

Query: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGK 337
           TY G +      G G    +DGLKYEG++  N    +G  T+PDG+  EG+
Sbjct: 108 TYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGE 158



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 18/57 (31%), Positives = 26/57 (45%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNI 342
           E+Y GE       G G +    G  Y G ++    HG G   + DG K EG + +N+
Sbjct: 84  ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNV 140



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 5   GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSH 45
           G+F +  G  Y G W   K HG G  T   G+  Y G++S+
Sbjct: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR-VYEGAFSN 336


>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
          Length = 870

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 46/141 (32%), Positives = 65/141 (46%), Gaps = 9/141 (6%)

Query: 9   FDDGGSYCGGWEDGKAHGHGV---CTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTW 65
           F  G +Y G + +G  HG G      G K +G++  +        GVYTWP G+ Y+G  
Sbjct: 103 FQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH---GVYTWPDGSMYEGEV 159

Query: 66  AQGKRHGIGLE--SKGKWVYKGEWTHGFK-GRYGVRECAGNGAKYEGTWSNGLQDGYGTE 122
             G R+G G+   S     Y G W +G + G+  +         YEG W   ++ G+G  
Sbjct: 160 VNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIR 219

Query: 123 TYSDGGTYQGQWVGGMRQGYG 143
            Y  G  Y+GQW   MR G G
Sbjct: 220 CYKSGNIYEGQWEDNMRHGEG 240



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 44/146 (30%), Positives = 62/146 (42%), Gaps = 19/146 (13%)

Query: 14  SYCGGWEDGKAHGHG-VCTGPKGQGEYTGSWSHGFEV-LGVYTWPSGNTYQGTWAQGKRH 71
           SY G W +GK HG G +    +G   Y G W    +   G+  + SGN Y+G W    RH
Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237

Query: 72  GIGLESKGKWV-----YKGEWTHGFKGRYGVRECAGNGAK---------YEGTWSNGLQD 117
           G   E + +W+     Y G W  G +  +G         +         Y G + NG + 
Sbjct: 238 G---EGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294

Query: 118 GYGTETYSDGGTYQGQWVGGMRQGYG 143
           G G   Y+ G  Y G+WV   + G G
Sbjct: 295 GRGKFYYASGAMYDGEWVSNKKHGMG 320



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 54/183 (29%), Positives = 73/183 (39%), Gaps = 43/183 (23%)

Query: 1   MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKG---QGEYTGSWSHGFEVLGVYTWPS 57
           M   G + + DG  Y G +       HGV T P G   +GE      +GF +    T P 
Sbjct: 118 MHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPV 177

Query: 58  GNTYQGTWAQGKRHGIG---LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSN- 113
             +Y G W  GKRHG G      +G   Y+G+W    K  +G+R C  +G  YEG W + 
Sbjct: 178 --SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIR-CYKSGNIYEGQWEDN 234

Query: 114 -----------------------GLQDGYGTET----------YSDGGTYQGQWVGGMRQ 140
                                  G+Q+G+GT T          Y     Y G++V G R 
Sbjct: 235 MRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294

Query: 141 GYG 143
           G G
Sbjct: 295 GRG 297



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 23/58 (39%), Positives = 34/58 (58%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
           Y+GE+ N  R G G    + G  Y+GEW SN++HG G +TF +G   EG +  + + G
Sbjct: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)

Query: 60  TYQGTWAQGKRHGIGLES-KGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDG 118
           +Y+G   +G   G G  + +G   Y+G ++ G     G    A +G KYEG +   +   
Sbjct: 85  SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWA-DGLKYEGDFVKNVPMN 143

Query: 119 YGTETYSDGGTYQGQWVGGMRQGYGV 144
           +G  T+ DG  Y+G+ V GMR G+G+
Sbjct: 144 HGVYTWPDGSMYEGEVVNGMRNGFGM 169



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 282 ATTTETYVGEWKNDKRSGFG-VSQRSDGLK-YEGEWASNRRHGYGCMTFPDGTKEEGKYK 339
           +T   +Y+G W N KR G G +    +G   YEG+W  N + G+G   +  G   EG+++
Sbjct: 173 STQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWE 232

Query: 340 QNILVGGKR 348
            N+  G  R
Sbjct: 233 DNMRHGEGR 241



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKE-EGKYKQNILVG 345
           Y G+W  + + G+G+     G  YEG+W  N RHG G M +    +E  G++++ I  G
Sbjct: 204 YEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNG 262



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 20/51 (39%), Positives = 28/51 (54%)

Query: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGK 337
           TY G +      G G    +DGLKYEG++  N    +G  T+PDG+  EG+
Sbjct: 108 TYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGE 158



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 18/57 (31%), Positives = 26/57 (45%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNI 342
           E+Y GE       G G +    G  Y G ++    HG G   + DG K EG + +N+
Sbjct: 84  ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNV 140



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 5   GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSH 45
           G+F +  G  Y G W   K HG G  T   G+  Y G++S+
Sbjct: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR-VYEGAFSN 336


>gi|18254456 testis-specific gene A2 [Homo sapiens]
          Length = 309

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 50/143 (34%), Positives = 67/143 (46%), Gaps = 8/143 (5%)

Query: 5   GRFNFDDGGSYCGGWEDGKAHGHGVC---TGPKGQGEYTGSWSHGFEVLGVYTWPSGNTY 61
           GR    +G +Y G +E GK HG G+     G +  GEY  +  HG    G + +P G+ Y
Sbjct: 34  GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90

Query: 62  QGTWAQGKRHGIGLESK-GKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG 120
           +G WA   RHG G+        Y GEW    +   G    A  G+KY GTW NG Q+G  
Sbjct: 91  EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG-T 149

Query: 121 TETYSDGGTYQGQWVGGMRQGYG 143
            E       YQG+++     G G
Sbjct: 150 AELIHLNHRYQGKFLNKNPVGPG 172



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 41/115 (35%), Positives = 58/115 (50%), Gaps = 4/115 (3%)

Query: 32  GPKGQGEYTGSWSHGFEV--LGVYTWPSGNTYQGTWAQGKRHGIGL-ESKGKWVYKGEWT 88
           G    GEY G  +   E    G    P+G+TY+G++  GKRHG G+ + K    Y GE+ 
Sbjct: 13  GENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72

Query: 89  HGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYG 143
              K   G      +G++YEG W+N L+ G+G   Y +  TY G+W    R G G
Sbjct: 73  RNKKHGQGTF-IYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQG 126



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 21/60 (35%), Positives = 38/60 (63%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
           +TY G ++  KR G G+ +  +G +Y GE+  N++HG G   +PDG++ EG++  ++  G
Sbjct: 42  DTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHG 101



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 19/51 (37%), Positives = 31/51 (60%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
           Y+GE+  +K+ G G     DG +YEGEWA++ RHG+G   + +     G++
Sbjct: 67  YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEW 117



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPD-GTKEEGKY 338
           Y GEW ND R G GV    +   Y GEW +++RHG G   + + G+K  G +
Sbjct: 90  YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTW 141



 Score = 36.6 bits (83), Expect = 0.087
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 5/61 (8%)

Query: 286 ETYVGEWKNDK-----RSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQ 340
           E  +GE++  +     R G G ++  +G  YEG +   +RHG G   F +G +  G+Y +
Sbjct: 14  ENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVR 73

Query: 341 N 341
           N
Sbjct: 74  N 74



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 1/38 (2%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSD-GLKYEGEWASNRRHG 322
           +TY GEW   +R G G    ++ G KY G W + ++ G
Sbjct: 111 DTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG 148


>gi|50355990 MORN repeat containing 3 [Homo sapiens]
          Length = 240

 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 47/141 (33%), Positives = 61/141 (43%), Gaps = 9/141 (6%)

Query: 11  DGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGF-EVLGVYTWPSGNT------YQG 63
           +G  Y G WED   HG G     K    Y G W  G  +  G  + P   T      Y G
Sbjct: 34  NGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSG 93

Query: 64  TWAQGKRHGIGLESKG-KWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTE 122
            W   K+ G G++  G K  Y+G+W    +  +G R    NG  YEG W N   +G G  
Sbjct: 94  WWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWG-RMYYSNGDIYEGQWENDKPNGEGML 152

Query: 123 TYSDGGTYQGQWVGGMRQGYG 143
              +G  Y+G W  GM+ G G
Sbjct: 153 RLKNGNRYEGCWERGMKNGAG 173



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 6/69 (8%)

Query: 83  YKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGT------YQGQWVG 136
           Y GEW    K   G +     GA YEG W  G +DGYGT +  D  T      Y G W G
Sbjct: 38  YVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKG 97

Query: 137 GMRQGYGVR 145
             + GYG++
Sbjct: 98  DKKSGYGIQ 106



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 20/54 (37%), Positives = 33/54 (61%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN 341
           Y G WK DK+SG+G+        YEG+W  ++R G+G M + +G   EG+++ +
Sbjct: 91  YSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWEND 144



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 21/63 (33%), Positives = 37/63 (58%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
           E Y G+W   +RSG+G    S+G  YEG+W +++ +G G +   +G + EG +++ +  G
Sbjct: 112 EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNG 171

Query: 346 GKR 348
             R
Sbjct: 172 AGR 174



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 3/74 (4%)

Query: 268 EAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQ-RSDGLKYEGEWASNRRHGYGCM 326
           + +A+   +   + A   + YVGEW+++ + G G    +  G  YEG+W   +R GYG +
Sbjct: 18  DRKAQRNGLRSQVYAVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTL 77

Query: 327 TFPDGTKEEGKYKQ 340
           + PD  ++ GK ++
Sbjct: 78  SLPD--QQTGKCRR 89



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 3/66 (4%)

Query: 2   SSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFE--VLGVYTWPSGN 59
           S  GR  + +G  Y G WE+ K +G G+     G   Y G W  G +      +    G 
Sbjct: 124 SGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNG-NRYEGCWERGMKNGAGRFFHLDHGQ 182

Query: 60  TYQGTW 65
            ++G W
Sbjct: 183 LFEGFW 188


>gi|13376267 MORN repeat containing 1 [Homo sapiens]
          Length = 497

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 66/236 (27%), Positives = 91/236 (38%), Gaps = 35/236 (14%)

Query: 5   GRFNFDDGGSYCGGWEDGKAHGHG---------------VCTGPKGQGE--------YTG 41
           G+  F DG  Y G + DG+  G G               V   P+G G         Y G
Sbjct: 52  GKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEG 111

Query: 42  SWSHGF-EVLGVYTWPSGNTYQGTWAQGKRHGIG--LESKGKWVYKGEWTHGFKGRYGVR 98
             SHG  E  G      G  YQG++   KRHG G  L   G   Y G+W    +  +GV 
Sbjct: 112 EVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGD-KYDGDWVRDRRQGHGVL 170

Query: 99  ECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSV--PYGMAAVI 156
            CA +G+ Y+G W + +  G G+  +  G TY G W+ G       R  +  P  M    
Sbjct: 171 RCA-DGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQ 229

Query: 157 RSPLRTSINSLR-----SEHTNGTALHPDASPAVAGSPAVSRGGFVLVAHSDSEIL 207
            SP   ++  L+     ++  +G  L   A        A S   F  V   + E L
Sbjct: 230 GSPFSVNVQLLQDHGEIAKSESGRVLQISAGVRYVQLSAYSEVNFFKVDRDNQETL 285



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 9/135 (6%)

Query: 15  YCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGV----YTWPSGNTYQGTWAQGKR 70
           Y G W+ G+ HGHG      G   Y G++  G E+ G     + W SG+T+ G +  G+ 
Sbjct: 39  YEGEWKAGRKHGHGKLLFKDGS-YYEGAFVDG-EITGEGRRHWAW-SGDTFSGQFVLGEP 95

Query: 71  HGIG-LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGT 129
            G G +E K    Y+GE +HG +  +G      +G  Y+G++ +  + G G   + +G  
Sbjct: 96  QGYGVMEYKAGGCYEGEVSHGMREGHGFL-VDRDGQVYQGSFHDNKRHGPGQMLFQNGDK 154

Query: 130 YQGQWVGGMRQGYGV 144
           Y G WV   RQG+GV
Sbjct: 155 YDGDWVRDRRQGHGV 169



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 51  GVYTWPSGN-TYQGTWAQGKRHGIG-LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYE 108
           GVY +P+    Y+G W  G++HG G L  K    Y+G +  G     G R  A +G  + 
Sbjct: 28  GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87

Query: 109 GTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYG 143
           G +  G   GYG   Y  GG Y+G+   GMR+G+G
Sbjct: 88  GQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHG 122



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 19/60 (31%), Positives = 35/60 (58%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
           + Y G + ++KR G G     +G KY+G+W  +RR G+G +   DG+  +G++  ++  G
Sbjct: 130 QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSG 189



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)

Query: 297 RSGFGVSQRSDGL-KYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKN 350
           R+G+GV    +   +YEGEW + R+HG+G + F DG+  EG +    + G  R++
Sbjct: 24  RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRH 78



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 19/51 (37%), Positives = 27/51 (52%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEG 336
           + Y G+W  D+R G GV + +DG  Y+G+W S+   G G M    G    G
Sbjct: 153 DKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYG 203



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 20/51 (39%), Positives = 27/51 (52%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
           Y GE  +  R G G     DG  Y+G +  N+RHG G M F +G K +G +
Sbjct: 109 YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 19/51 (37%), Positives = 26/51 (50%)

Query: 95  YGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVR 145
           YGV     +  +YEG W  G + G+G   + DG  Y+G +V G   G G R
Sbjct: 27  YGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRR 77



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 18/60 (30%), Positives = 31/60 (51%)

Query: 282 ATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN 341
           A + +T+ G++   +  G+GV +   G  YEGE +   R G+G +   DG   +G +  N
Sbjct: 80  AWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDN 139



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 23/82 (28%), Positives = 29/82 (35%), Gaps = 24/82 (29%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEW------ASNRRH------------------GY 323
           Y GEWK  ++ G G     DG  YEG +         RRH                  GY
Sbjct: 39  YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGY 98

Query: 324 GCMTFPDGTKEEGKYKQNILVG 345
           G M +  G   EG+    +  G
Sbjct: 99  GVMEYKAGGCYEGEVSHGMREG 120



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 12/29 (41%), Positives = 15/29 (51%)

Query: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEW 315
           TY G+W +D  SG G      G+ Y G W
Sbjct: 177 TYKGQWHSDVFSGLGSMAHCSGVTYYGLW 205


>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
          Length = 953

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 48/144 (33%), Positives = 62/144 (43%), Gaps = 16/144 (11%)

Query: 14  SYCGGWEDGKAHGHGVCTGPKGQ---GEYTGSWSHGFEVLGVYTWPSG-----NTYQGTW 65
           +Y G W  G+ HG G    P G+   G +     HGF   G+   P       + Y+  W
Sbjct: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGF---GIRLLPQASEDKFDCYKCHW 413

Query: 66  AQGKRHGIGL-ESKGKWVYKGEWTHGFKGRYGVREC---AGNGAKYEGTWSNGLQDGYGT 121
            +G   G G+ E     VYKG +  G +  +GV E    A    +Y G W  G + GYG 
Sbjct: 414 REGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473

Query: 122 ETYSD-GGTYQGQWVGGMRQGYGV 144
           E   D G  Y G W  G R G GV
Sbjct: 474 EEDGDRGERYIGMWQAGQRHGPGV 497



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 41/150 (27%), Positives = 61/150 (40%), Gaps = 10/150 (6%)

Query: 5   GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGE----YTGSWSHGFEV-LGVYTWPSGN 59
           G   + DG ++ G +  G  HG G+   P+   +    Y   W  G     G+  + +  
Sbjct: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430

Query: 60  TYQGTWAQGKRHGIGLESKGKWV-----YKGEWTHGFKGRYGVRECAGNGAKYEGTWSNG 114
            Y+G + +G RHG G+   G        Y G W  G +  YG+ E    G +Y G W  G
Sbjct: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490

Query: 115 LQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
            + G G      G  YQG +      G G+
Sbjct: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 12/122 (9%)

Query: 36  QGEYTGSWSHGF-EVLGVYTWPSGNTYQGTWAQGKRHGIGLE-----SKGKW-VYKGEWT 88
           Q  Y G W  G     G   WP G  + G + QG  HG G+      S+ K+  YK  W 
Sbjct: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414

Query: 89  HGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGT----YQGQWVGGMRQGYGV 144
            G    YG+ E + +   Y+G +  GL+ G+G             Y G W  G R GYG+
Sbjct: 415 EGSMCGYGICEYSTDEV-YKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473

Query: 145 RQ 146
            +
Sbjct: 474 EE 475



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 275 VIEDDIDATTTETYVGEWKNDKRSGFGVSQRSD-GLKYEGEWASNRRHGYGCMTFPDGTK 333
           V+E    A     Y G W+  +RSG+G+ +  D G +Y G W + +RHG G M    G  
Sbjct: 446 VLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVC 505

Query: 334 EEGKYKQNILVG 345
            +G ++ +  VG
Sbjct: 506 YQGTFQADKTVG 517



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 55/254 (21%), Positives = 88/254 (34%), Gaps = 66/254 (25%)

Query: 105 AKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSI 164
           A YEG W  G   G GT  + DG  + G +  G+                          
Sbjct: 356 ATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGL-------------------------- 389

Query: 165 NSLRSEHTNGTALHPDASPAVAGSPAV-----SRGGFVLVAHSDSEILKSKKKGLFRRSL 219
                EH  G  L P AS              S  G+ +  +S  E+ K    G F+  L
Sbjct: 390 -----EHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYK----GYFQEGL 440

Query: 220 LSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDD 279
             G  + +S  ++    + +        +G                          IE+D
Sbjct: 441 RHGFGVLESGPQAPQPFRYTGHWERGQRSGYG------------------------IEED 476

Query: 280 IDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYK 339
            D    E Y+G W+  +R G GV     G+ Y+G + +++  G G +   D +  EG + 
Sbjct: 477 GDRG--ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFT 534

Query: 340 QNILVGGKRKNLIP 353
           +++ + GK K   P
Sbjct: 535 RDLTLMGKGKVTFP 548


>gi|40316935 alsin isoform 1 [Homo sapiens]
          Length = 1657

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 49/165 (29%), Positives = 64/165 (38%), Gaps = 34/165 (20%)

Query: 14   SYCGGWEDGKAHGHGVCTGPKGQ--------------GEY-------------TGSWSHG 46
            +Y G W  GK HG GV   P G+              GEY              G W  G
Sbjct: 1048 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEG 1107

Query: 47   FEV-LGVYTWPSGNTYQGTWAQGKRHGIGLESKGKW------VYKGEWTHGFKGRYGVRE 99
                 GVY++ SG  ++G +    RHG GL   GK       ++ G+W    K  YGV +
Sbjct: 1108 KMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFD 1167

Query: 100  CAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
                G KY G W + +  G G      G  Y+G +      G GV
Sbjct: 1168 DITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGV 1212



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 11/96 (11%)

Query: 60   TYQGTWAQGKRHGIGLESKGKW----VYKGEWTHGFKGRYGVRECAGNGAK----YEGTW 111
            TY G W  GK HG G+    KW    +Y G + +G +  YG              Y G W
Sbjct: 1048 TYDGRWLSGKPHGRGVL---KWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHW 1104

Query: 112  SNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQS 147
              G   G G  +Y+ G  ++G +   MR G+G+ +S
Sbjct: 1105 KEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRS 1140



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 25/73 (34%), Positives = 36/73 (49%)

Query: 281  DATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQ 340
            D T  E Y+G W++D   G GV     GL YEG +  N+  G G +   D T  EG++  
Sbjct: 1168 DITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSD 1227

Query: 341  NILVGGKRKNLIP 353
            +  + GK    +P
Sbjct: 1228 DWTLSGKGTLTMP 1240



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 39/159 (24%), Positives = 62/159 (38%), Gaps = 29/159 (18%)

Query: 1    MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPK----GQGEYTGSW----SHGFEVLGV 52
            M   G +++  G  + G ++D   HGHG+    K        + G W      G+ V   
Sbjct: 1109 MCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDD 1168

Query: 53   YTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAK------ 106
             T   G  Y G W      G G+      +Y       ++G + + +  GNG        
Sbjct: 1169 IT--RGEKYMGMWQDDVCQGNGVVVTQFGLY-------YEGNFHLNKMMGNGVLLSEDDT 1219

Query: 107  -YEGTWSNG-LQDGYGTETYSDG----GTYQGQWVGGMR 139
             YEG +S+     G GT T  +G    G + G+W  G++
Sbjct: 1220 IYEGEFSDDWTLSGKGTLTMPNGDYIEGYFSGEWGSGIK 1258



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 280  IDATTTETYVGEWKNDKRSGFGV-SQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
            + +++   ++G+W  DK++G+GV    + G KY G W  +   G G +    G   EG +
Sbjct: 1143 LTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNF 1202

Query: 339  KQNILVG 345
              N ++G
Sbjct: 1203 HLNKMMG 1209



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 17/39 (43%), Positives = 22/39 (56%)

Query: 288  YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCM 326
            YVG WK  K  G GV   + G  +EG +  N RHG+G +
Sbjct: 1100 YVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLL 1138



 Score = 36.6 bits (83), Expect = 0.087
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 105  AKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYG 143
            A Y+G W +G   G G   + DG  Y G +  G+  GYG
Sbjct: 1047 ATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYG 1085



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 311  YEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRA 356
            Y+G W S + HG G + +PDG    G ++ N L  G  +  IP +A
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFR-NGLEDGYGEYRIPNKA 1093



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 287  TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDG--TKEE---GKYKQN 341
            TY G W + K  G GV +  DG  Y G + +    GYG    P+    KE+   G +K+ 
Sbjct: 1048 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEG 1107

Query: 342  ILVG 345
             + G
Sbjct: 1108 KMCG 1111



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 4/61 (6%)

Query: 1    MSSGGRFNFDDGGSYCGGW-EDGKAHGHGVCTGPKG---QGEYTGSWSHGFEVLGVYTWP 56
            M   G    +D   Y G + +D    G G  T P G   +G ++G W  G ++ G Y  P
Sbjct: 1207 MMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPNGDYIEGYFSGEWGSGIKITGTYFKP 1266

Query: 57   S 57
            S
Sbjct: 1267 S 1267


>gi|149999376 MORN repeat containing 4 [Homo sapiens]
          Length = 146

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 25/124 (20%)

Query: 5   GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHG-FEVLGVYTWPSGNTYQG 63
           G F +  G  Y G W++G+ HG G      G G Y G + +G F   GV T+  G+ Y+G
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSRYEG 64

Query: 64  TWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTET 123
            +AQGK +G+G+                  RY       +   +EG + NG  DG+G  T
Sbjct: 65  EFAQGKFNGVGVFI----------------RY-------DNMTFEGEFKNGRVDGFGLLT 101

Query: 124 YSDG 127
           + DG
Sbjct: 102 FPDG 105



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 2/95 (2%)

Query: 51  GVYTWPSGNTYQGTWAQGKRHGIG-LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEG 109
           G +T+ SG  Y+G W +G+RHG G L       Y G + +G    +GV   + +G++YEG
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFS-DGSRYEG 64

Query: 110 TWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
            ++ G  +G G     D  T++G++  G   G+G+
Sbjct: 65  EFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 23/55 (41%), Positives = 34/55 (61%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQ 340
           E Y GEWK  +R GFG    +DG  Y G + +   +G+G +TF DG++ EG++ Q
Sbjct: 14  EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQ 68



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 37/117 (31%)

Query: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWA-----------------------SNRRHGY 323
           TY+G ++N   +GFGV   SDG +YEGE+A                       + R  G+
Sbjct: 38  TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97

Query: 324 GCMTFPDGT----KEEGKYKQNILVGGKRKNLIPLRASKIREKVDRAVEAAERAATI 376
           G +TFPDG+    + EG ++ N L          LR  K    V RA  A++ A  +
Sbjct: 98  GLLTFPDGSHGIPRNEGLFENNKL----------LRREKCSAIVQRAQSASKSARNL 144



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 16/40 (40%), Positives = 22/40 (55%)

Query: 306 SDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
           S G +Y GEW   RRHG+G + F DG    G ++  +  G
Sbjct: 11  SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNG 50


>gi|30520314 MORN repeat containing 4 [Homo sapiens]
          Length = 146

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 25/124 (20%)

Query: 5   GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHG-FEVLGVYTWPSGNTYQG 63
           G F +  G  Y G W++G+ HG G      G G Y G + +G F   GV T+  G+ Y+G
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSRYEG 64

Query: 64  TWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTET 123
            +AQGK +G+G+                  RY       +   +EG + NG  DG+G  T
Sbjct: 65  EFAQGKFNGVGVFI----------------RY-------DNMTFEGEFKNGRVDGFGLLT 101

Query: 124 YSDG 127
           + DG
Sbjct: 102 FPDG 105



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 2/95 (2%)

Query: 51  GVYTWPSGNTYQGTWAQGKRHGIG-LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEG 109
           G +T+ SG  Y+G W +G+RHG G L       Y G + +G    +GV   + +G++YEG
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFS-DGSRYEG 64

Query: 110 TWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
            ++ G  +G G     D  T++G++  G   G+G+
Sbjct: 65  EFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 23/55 (41%), Positives = 34/55 (61%)

Query: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQ 340
           E Y GEWK  +R GFG    +DG  Y G + +   +G+G +TF DG++ EG++ Q
Sbjct: 14  EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQ 68



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 37/117 (31%)

Query: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWA-----------------------SNRRHGY 323
           TY+G ++N   +GFGV   SDG +YEGE+A                       + R  G+
Sbjct: 38  TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97

Query: 324 GCMTFPDGT----KEEGKYKQNILVGGKRKNLIPLRASKIREKVDRAVEAAERAATI 376
           G +TFPDG+    + EG ++ N L          LR  K    V RA  A++ A  +
Sbjct: 98  GLLTFPDGSHGIPRNEGLFENNKL----------LRREKCSAIVQRAQSASKSARNL 144



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 16/40 (40%), Positives = 22/40 (55%)

Query: 306 SDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
           S G +Y GEW   RRHG+G + F DG    G ++  +  G
Sbjct: 11  SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNG 50


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 32/124 (25%), Positives = 42/124 (33%), Gaps = 14/124 (11%)

Query: 41   GSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVREC 100
            G+W+   E      W  G T +GTWA  K  G            G W     G   + E 
Sbjct: 1270 GTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSW--ALAGNQAIGEL 1327

Query: 101  AGNGAKYEGTWSNGLQDGY---------GTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG 151
               G   +G+W  G   G          G+ T ++    +G W G    G G   SV Y 
Sbjct: 1328 WAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGA---GAGNMSSVSYW 1384

Query: 152  MAAV 155
               V
Sbjct: 1385 AGVV 1388


>gi|224282170 MORN repeat containing 2 [Homo sapiens]
          Length = 79

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 19/48 (39%), Positives = 27/48 (56%)

Query: 298 SGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
           +GFG  +   G  YEG++  N  HG G  TFP+G K  G + +N + G
Sbjct: 2   NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEG 49



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 2/66 (3%)

Query: 1  MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHG-FEVLGVYTWPSGN 59
          M+  GR     G  Y G ++D   HG G  T P G  +YTG+++    E  G YT   G 
Sbjct: 1  MNGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNG-AKYTGNFNENRVEGEGEYTDIQGL 59

Query: 60 TYQGTW 65
           + G +
Sbjct: 60 EWSGNF 65



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 14/41 (34%), Positives = 22/41 (53%)

Query: 103 NGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYG 143
           +GA YEG + + +  G GT T+ +G  Y G +     +G G
Sbjct: 11  SGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEG 51



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 16/51 (31%), Positives = 24/51 (47%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
           Y G++K++   G G     +G KY G +  NR  G G  T   G +  G +
Sbjct: 15  YEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWSGNF 65


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 53/213 (24%), Positives = 75/213 (35%), Gaps = 44/213 (20%)

Query: 366 AVEAAERAATI---------AKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITA 416
           AV AA  AAT+         A     + +   + S+AKA AA  AA  A   A       
Sbjct: 430 AVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAGSGAP 489

Query: 417 KEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSP 476
           +    +   +E+GL                       ++  P    +G    D T +  P
Sbjct: 490 EPLDGAEPAKESGLG---------------------AEERCPSALSRGPLDEDGTDEALP 528

Query: 477 LQSFPTSPAATPPPAPAARNKVAHFSRQVSVDEERGGDIQMLLEGRAGDCARSSWGEEQA 536
               P +P   PPP PA +       R V  D E    +           AR ++G   A
Sbjct: 529 P---PLAPLPPPPPPPARKGSYVSAFRPVVKDTESIAKLY--------GSAREAYG---A 574

Query: 537 GGSRGVRSGALRGGLLVDDFRTRGSGRKQPGNP 569
           G +RG   GA  GG +  DF + GS      +P
Sbjct: 575 GPARGPGPGAGSGGYVSPDFLSEGSSSYNSASP 607


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 9/145 (6%)

Query: 354  LRASKIREKVD-RAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQK----AQEE 408
            L+ ++I+EK+  R+ E          Q     +SR   S   +E+A   A +    A+  
Sbjct: 1302 LQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSP 1361

Query: 409  ARIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGT-TP 467
            ++    T K   P    +E  L + R    +S D  E  S  + +Q E       G  +P
Sbjct: 1362 SKSGAQTPKS-PPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISP 1420

Query: 468  SDLTPDDSPLQSFPTSPAATPPPAP 492
            SDL   DSP Q+ P S + TPPP P
Sbjct: 1421 SDLP--DSPGQTMPPSRSKTPPPPP 1443


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 9/145 (6%)

Query: 354  LRASKIREKVD-RAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQK----AQEE 408
            L+ ++I+EK+  R+ E          Q     +SR   S   +E+A   A +    A+  
Sbjct: 1302 LQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSP 1361

Query: 409  ARIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGT-TP 467
            ++    T K   P    +E  L + R    +S D  E  S  + +Q E       G  +P
Sbjct: 1362 SKSGAQTPKS-PPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISP 1420

Query: 468  SDLTPDDSPLQSFPTSPAATPPPAP 492
            SDL   DSP Q+ P S + TPPP P
Sbjct: 1421 SDLP--DSPGQTMPPSRSKTPPPPP 1443


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 9/145 (6%)

Query: 354  LRASKIREKVD-RAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQK----AQEE 408
            L+ ++I+EK+  R+ E          Q     +SR   S   +E+A   A +    A+  
Sbjct: 1302 LQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSP 1361

Query: 409  ARIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGT-TP 467
            ++    T K   P    +E  L + R    +S D  E  S  + +Q E       G  +P
Sbjct: 1362 SKSGAQTPKS-PPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISP 1420

Query: 468  SDLTPDDSPLQSFPTSPAATPPPAP 492
            SDL   DSP Q+ P S + TPPP P
Sbjct: 1421 SDLP--DSPGQTMPPSRSKTPPPPP 1443


>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
          Length = 518

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 40/130 (30%), Positives = 50/130 (38%), Gaps = 14/130 (10%)

Query: 3   SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQ 62
           SGG   + DGG    G++ G  HG          G Y G    GF+    YT   G+ YQ
Sbjct: 388 SGGGGGYQDGGYRDSGFQPGGYHGG------HSSGGYQGGGYGGFQTSSSYT---GSGYQ 438

Query: 63  GT-WAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGT 121
           G  + Q  R+  G    G    +G    G  GR G    AG G  + G  S     G   
Sbjct: 439 GGGYQQDNRYQDG----GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQF 494

Query: 122 ETYSDGGTYQ 131
           E +   G YQ
Sbjct: 495 EQHFQHGGYQ 504



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 44/151 (29%), Positives = 57/151 (37%), Gaps = 24/151 (15%)

Query: 3   SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQ 62
           +GGR      G   GG+E     G G      G+G   G + HG    G      GN +Q
Sbjct: 333 TGGR------GGGRGGYEHSSYGGRGGHEQGGGRGG-RGGYDHGGRGGG-----RGNKHQ 380

Query: 63  GTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNG-------AKYEGTWSNGL 115
           G W  G   G G    G +   G    G+ G +      G G       + Y G+   G 
Sbjct: 381 GGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQG- 439

Query: 116 QDGYGTET-YSDGGTYQGQWVGGMRQGYGVR 145
             GY  +  Y DGG +  +  GG R G G R
Sbjct: 440 -GGYQQDNRYQDGGHHGDR--GGGRGGRGGR 467


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 55/221 (24%), Positives = 85/221 (38%), Gaps = 37/221 (16%)

Query: 428  NGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPTSPAAT 487
            NG+EYQ    +     I+V +   P     P       + + +TP+    ++ P  PAAT
Sbjct: 849  NGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPES---KAPPPLPAAT 905

Query: 488  P---PPAPAARNKVAH---FSRQVSVDEERGGDIQMLLEGRAGDCAR-------SSWGEE 534
            P    P P  R   A     +R + +            + R G   +       S    E
Sbjct: 906  PDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAE 965

Query: 535  QAGGSRGVRSGALRGGLLVDDFRTRGSGRKQPGNPKPRERRTESPPVFTWTSHHRASNHS 594
             +G   G R+  LR        R  G G + P  P+PR  RT++P           ++ +
Sbjct: 966  GSGSGGGGRASGLR------PRRNDGLGERPP--PRPRRPRTQAP--------GSRADPA 1009

Query: 595  PGGSRLLELQEEKLSNYRMEMKPLLRMETHPQKRRYSKGGA 635
            P   R   L EE  S+ R  + P       P+KR+ ++GGA
Sbjct: 1010 PRVPRAAALPEETRSSRRRRLPP----RKDPRKRK-ARGGA 1045


>gi|75750529 ankyrin repeat and MYND domain containing 1 isoform 1
           [Homo sapiens]
          Length = 941

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 30/112 (26%)

Query: 26  GHGVCTGPKGQ---GEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWV 82
           G+G  + P G+   G++     HG   LG Y WP G+++ GT+    R G G        
Sbjct: 13  GYGKFSWPTGESYHGQFYRDHCHG---LGTYMWPDGSSFTGTFYLSHREGYG-------- 61

Query: 83  YKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQW 134
                T   K R            ++G +    + G G ETY DG    G W
Sbjct: 62  -----TMYMKTRL-----------FQGLYKADQRFGPGVETYPDGSQDVGLW 97



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 22/83 (26%)

Query: 284 TTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCM----------------- 326
           T E+Y G++  D   G G     DG  + G +  + R GYG M                 
Sbjct: 21  TGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTMYMKTRLFQGLYKADQRF 80

Query: 327 -----TFPDGTKEEGKYKQNILV 344
                T+PDG+++ G + +  L+
Sbjct: 81  GPGVETYPDGSQDVGLWFREQLI 103



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 15/51 (29%), Positives = 25/51 (49%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
           Y GE+  + + G+G      G  Y G++  +  HG G   +PDG+   G +
Sbjct: 2   YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTF 52



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 82  VYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQG 141
           +Y+GE+    K  YG +     G  Y G +      G GT  + DG ++ G +    R+G
Sbjct: 1   MYQGEFGLNMKLGYG-KFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREG 59

Query: 142 YG 143
           YG
Sbjct: 60  YG 61


>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
           [Homo sapiens]
          Length = 372

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 45/153 (29%), Positives = 63/153 (41%), Gaps = 26/153 (16%)

Query: 4   GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGE-YTGSWSHGFEVLGVYTWPSGNTYQ 62
           GG  NF  GG++ G    G + G G   G  G G+ Y G  + G    G   +  G+   
Sbjct: 211 GGNDNFGRGGNFSGRGGFGGSRGGG---GYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGY 267

Query: 63  GTWAQG-KRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGT 121
           G+  QG    G G    G +     + +G  G +G     G+G+ + G  S         
Sbjct: 268 GSGGQGYGNQGSGYGGSGSY---DSYNNGGGGGFG----GGSGSNFGGGGS--------- 311

Query: 122 ETYSDGGTYQGQW--VGGMRQG-YGVRQSVPYG 151
             Y+D G Y  Q    G M+ G +G R S PYG
Sbjct: 312 --YNDFGNYNNQSSNFGPMKGGNFGGRSSGPYG 342


>gi|20357556 cortactin isoform b [Homo sapiens]
          Length = 513

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 50/236 (21%), Positives = 86/236 (36%), Gaps = 29/236 (12%)

Query: 292 WKNDKRSGFGVSQRSDGLKYEGEWASNR-RHGYGCMTFPDGTKEEGKYKQNILVGGKRKN 350
           W + ++     SQ+     + G++   + R      TF D T+    Y++ + V      
Sbjct: 250 WDHQEKLQLHESQKDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSK 309

Query: 351 LIPLRAS-----KIREKVDRAVEAAERAATIAKQKAEIAASR---TSHSRAKAEAALTAA 402
              +RA+     K +E+ DR    AERA  +AK++ E   +R      +RAK +    + 
Sbjct: 310 TSNIRANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSP 369

Query: 403 QKAQEEARIARITAKEFSPSFQHRENGLEYQRPKRQTSCD--------DIEVLSTGTPLQ 454
                E R+      E + SF+     L Y+ P   T  +        D    S+   L 
Sbjct: 370 APQPTEERLPSSPVYEDAASFKAE---LSYRGPVSGTEPEPVYSMEAADYREASSQQGLA 426

Query: 455 QESPELYRKGTTPSDLTPDDSPLQSFPTSPAATPPPAPAARNKVAHFSRQVSVDEE 510
             +  +Y     P     +DS    +      T          VA +  Q + D+E
Sbjct: 427 YATEAVYESAEAPGHYPAEDSTYDEYENDLGIT---------AVALYDYQAAGDDE 473


>gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2
           [Homo sapiens]
          Length = 717

 Score = 38.1 bits (87), Expect = 0.030
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)

Query: 9   FDDGGSYCGGWEDGKAHGHGVCTGPKGQ---GEYTGSWSHGFEVLGVYTWPSGNTYQGTW 65
           + DG  Y G +      G+G  + P G+   G++     HG   LG Y WP G+++ GT+
Sbjct: 85  WQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHG---LGTYMWPDGSSFTGTF 141

Query: 66  AQGKRHGIG 74
               R G G
Sbjct: 142 YLSHREGYG 150



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 221 SGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDI 280
           +G + R  E K        +  S ++ A  +T      D+ +     E EAE  +   D+
Sbjct: 17  AGSRQRPLEGKGGETPAAEEPGSLKNYAVFAT-----RDVSAAPEKEEEEAEGPLRAQDL 71

Query: 281 DATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
                E+Y+   +       GV +  DG  Y+GE+  N + GYG  ++P G    G++
Sbjct: 72  ----RESYIQLVQ-------GVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQF 118



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 23/95 (24%)

Query: 49  VLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYE 108
           V GV  W  G  YQG +    + G G         K  W                G  Y 
Sbjct: 79  VQGVQEWQDGCMYQGEFGLNMKLGYG---------KFSWP--------------TGESYH 115

Query: 109 GTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYG 143
           G +      G GT  + DG ++ G +    R+GYG
Sbjct: 116 GQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 150



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 15/51 (29%), Positives = 25/51 (49%)

Query: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
           Y GE+  + + G+G      G  Y G++  +  HG G   +PDG+   G +
Sbjct: 91  YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTF 141



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 15/43 (34%), Positives = 21/43 (48%)

Query: 284 TTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCM 326
           T E+Y G++  D   G G     DG  + G +  + R GYG M
Sbjct: 110 TGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTM 152


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 37.7 bits (86), Expect = 0.039
 Identities = 54/249 (21%), Positives = 92/249 (36%), Gaps = 24/249 (9%)

Query: 224 KLRKSESKSSLAS---QRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDI 280
           KLRK + K  L +    +SKQ   + +    TV S  +     I   E +AE     +D 
Sbjct: 249 KLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAED- 307

Query: 281 DATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMT------FPDGTKE 334
                +    + K DK+   G  +  +  K +G   +  +     +            +E
Sbjct: 308 -----DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE 362

Query: 335 EGKYKQNILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAK 394
           E + K+   +  KRK    L   K   K  +  E  ER     K++ ++       +RA+
Sbjct: 363 EERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER----LKKEGKLLTKSQREARAR 418

Query: 395 AEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKRQTS-----CDDIEVLST 449
           AEA L   Q    E        K+       +   +  Q   ++ S     C  +EV+  
Sbjct: 419 AEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQ 478

Query: 450 GTPLQQESP 458
           G P ++E+P
Sbjct: 479 GVPEKEETP 487


>gi|223278407 MORN repeat containing 5 [Homo sapiens]
          Length = 161

 Score = 37.0 bits (84), Expect = 0.067
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 1/47 (2%)

Query: 15 YCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTY 61
          Y G  +DG  HG G    P G  +Y   W +G  + G YT+  G  Y
Sbjct: 31 YVGEMKDGMFHGEGTLYFPSGS-QYDAIWENGLAIKGTYTFSDGLHY 76



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 15/63 (23%), Positives = 27/63 (42%)

Query: 284 TTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNIL 343
           T   Y+GE+ + +  G           Y GE      HG G + FP G++ +  ++  + 
Sbjct: 4   TGSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIWENGLA 63

Query: 344 VGG 346
           + G
Sbjct: 64  IKG 66


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 36.6 bits (83), Expect = 0.087
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 3/99 (3%)

Query: 367  VEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHR 426
            +E    AA+    +  + A RTS    +A+   ++ +K QE    A + A   S S    
Sbjct: 2652 LELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVT-AEVAAPSTSSSATSS 2710

Query: 427  ENGLEYQRPKRQTSCDDIEV--LSTGTPLQQESPELYRK 463
              G    RP R+ +  D+E+    TG P Q   P++ RK
Sbjct: 2711 PEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRK 2749


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,582,372
Number of Sequences: 37866
Number of extensions: 1669932
Number of successful extensions: 7338
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 172
Number of HSP's that attempted gapping in prelim test: 6537
Number of HSP's gapped (non-prelim): 639
length of query: 748
length of database: 18,247,518
effective HSP length: 110
effective length of query: 638
effective length of database: 14,082,258
effective search space: 8984480604
effective search space used: 8984480604
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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