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Search of human proteins with 21450853
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
[Homo sapiens]
(480 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [... 1005 0.0
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H... 972 0.0
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 677 0.0
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa... 671 0.0
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [... 282 4e-76
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [... 282 4e-76
gi|4505531 oxysterol binding protein [Homo sapiens] 282 4e-76
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] 278 6e-75
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 272 6e-73
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [... 268 8e-72
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [... 268 8e-72
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [... 268 8e-72
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [... 268 8e-72
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [... 134 2e-31
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ... 134 2e-31
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [... 134 2e-31
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 133 3e-31
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 133 3e-31
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap... 109 5e-24
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap... 109 5e-24
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap... 109 5e-24
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap... 109 5e-24
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap... 109 5e-24
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap... 109 5e-24
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap... 109 5e-24
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 94 4e-19
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] 89 1e-17
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 39 0.014
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 39 0.014
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 39 0.014
>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
[Homo sapiens]
Length = 480
Score = 1005 bits (2598), Expect = 0.0
Identities = 480/480 (100%), Positives = 480/480 (100%)
Query: 1 MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH 60
MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
Sbjct: 1 MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH 60
Query: 61 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA 120
RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
Sbjct: 61 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA 120
Query: 121 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP 180
SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
Sbjct: 121 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP 180
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
Sbjct: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG 300
NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
Sbjct: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG 300
Query: 301 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS 360
KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
Sbjct: 301 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS 360
Query: 361 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS 420
KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
Sbjct: 361 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS 420
Query: 421 QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY 480
QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
Sbjct: 421 QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY 480
>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
sapiens]
Length = 468
Score = 972 bits (2512), Expect = 0.0
Identities = 468/480 (97%), Positives = 468/480 (97%), Gaps = 12/480 (2%)
Query: 1 MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH 60
MNGEEEFFDAVT EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
Sbjct: 1 MNGEEEFFDAVT------------EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH 48
Query: 61 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA 120
RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
Sbjct: 49 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA 108
Query: 121 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP 180
SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
Sbjct: 109 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP 168
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
Sbjct: 169 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 228
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG 300
NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
Sbjct: 229 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG 288
Query: 301 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS 360
KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
Sbjct: 289 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS 348
Query: 361 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS 420
KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
Sbjct: 349 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS 408
Query: 421 QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY 480
QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
Sbjct: 409 QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY 468
>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
sapiens]
Length = 950
Score = 677 bits (1748), Expect = 0.0
Identities = 316/488 (64%), Positives = 388/488 (79%), Gaps = 21/488 (4%)
Query: 4 EEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQE--------- 54
E+EF+DA++ +S+ S + + +G R S+E
Sbjct: 473 EDEFYDALSDSESERSLSRLEAVTARSF------EEEGEHLGSRKHRMSEEKDCGGGDAL 526
Query: 55 -NGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEH 113
NGI+KHRTSLP+PMFSR+DFS+W+IL+KC+G+ELSKITMP+ FNEPLSFLQR+TEYMEH
Sbjct: 527 SNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEH 586
Query: 114 VYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFIS 173
YLIH+AS P+ERMQ VAAFAVSAVASQWERTGKPFNPLLGETYEL+R+DLGFR IS
Sbjct: 587 TYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLIS 646
Query: 174 EQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWT 233
EQVSHHPPISAFH+EGLN+DF+FHGSIYPKLKFWGKSVEAEP+GTITLELL+HNEAYTWT
Sbjct: 647 EQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWT 706
Query: 234 NPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKK 293
NPTCCVHN+I+GKLWIEQYG VEI+NH+TG KCVL+FKPCGLFGKELHKVEG+IQDK+KK
Sbjct: 707 NPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKK 766
Query: 294 KLFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVA-QE 352
KL +YGKWTECL+ +DP +++++KK +++ +K + S+ D++PV E
Sbjct: 767 KLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKK----NSKQMSTSEELDEMPVPDSE 822
Query: 353 TVQVIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGME 412
+V +IPGS LLWRI RPPNSAQMYNFTSF + LNE++ ME +P TDCRLRPDIR ME
Sbjct: 823 SVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAME 882
Query: 413 NGNMDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERN 472
NG +D AS+EK+RLEEKQR AR+ R+K E +W+TRWF+ G NPY G DW+Y+G Y++RN
Sbjct: 883 NGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWDRN 942
Query: 473 FSDCPDIY 480
+ + PDIY
Sbjct: 943 YFNLPDIY 950
>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
sapiens]
Length = 437
Score = 671 bits (1731), Expect = 0.0
Identities = 305/427 (71%), Positives = 367/427 (85%), Gaps = 5/427 (1%)
Query: 55 NGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHV 114
NGI+KHRTSLP+PMFSR+DFS+W+IL+KC+G+ELSKITMP+ FNEPLSFLQR+TEYMEH
Sbjct: 15 NGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHT 74
Query: 115 YLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISE 174
YLIH+AS P+ERMQ VAAFAVSAVASQWERTGKPFNPLLGETYEL+R+DLGFR ISE
Sbjct: 75 YLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISE 134
Query: 175 QVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTN 234
QVSHHPPISAFH+EGLN+DF+FHGSIYPKLKFWGKSVEAEP+GTITLELL+HNEAYTWTN
Sbjct: 135 QVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTN 194
Query: 235 PTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKK 294
PTCCVHN+I+GKLWIEQYG VEI+NH+TG KCVL+FKPCGLFGKELHKVEG+IQDK+KKK
Sbjct: 195 PTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKK 254
Query: 295 LFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVA-QET 353
L +YGKWTECL+ +DP +++++KK +++ +K + S+ D++PV E+
Sbjct: 255 LCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKK----NSKQMSTSEELDEMPVPDSES 310
Query: 354 VQVIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMEN 413
V +IPGS LLWRI RPPNSAQMYNFTSF + LNE++ ME +P TDCRLRPDIR MEN
Sbjct: 311 VFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMEN 370
Query: 414 GNMDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNF 473
G +D AS+EK+RLEEKQR AR+ R+K E +W+TRWF+ G NPY G DW+Y+G Y++RN+
Sbjct: 371 GEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWDRNY 430
Query: 474 SDCPDIY 480
+ PDIY
Sbjct: 431 FNLPDIY 437
>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
[Homo sapiens]
Length = 938
Score = 282 bits (722), Expect = 4e-76
Identities = 171/454 (37%), Positives = 236/454 (51%), Gaps = 59/454 (12%)
Query: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGI------Q 58
EFFDA S +SS E S+ ++ + D + N + R +
Sbjct: 498 EFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRN 557
Query: 59 KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 118
R LPAP S+ ++W IL+ +G +LSK++MP+ NEPL+ LQ + E ME+ L+
Sbjct: 558 GRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLD 617
Query: 119 RASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVS 177
+AS P ERM VAAFAVS S + R G KPFNP+LGETYE IRED GFRF SEQVS
Sbjct: 618 KASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVS 677
Query: 178 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 237
HHPPISA H E N F+F I K KFWGKS+E P GT+ + L K+ + Y W T
Sbjct: 678 HHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTT 735
Query: 238 CVHNVIIGKLWIEQYGTVEILNHRTG-HKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF 296
C+HN++ G+ WIE YG V I N ++ C L F + +++V+G + D+ K ++
Sbjct: 736 CIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVY 795
Query: 297 MIYGKWTECLW-GIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
++GKW E L+ G+ P
Sbjct: 796 RLFGKWHEGLYCGVAP-------------------------------------------- 811
Query: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
+K +WR + P N Y FT F + LNEL+ ++ LPPTD R RPD R +E GN
Sbjct: 812 ---SAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGN 868
Query: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWF 449
++ A+ EK+R+EE QR RR + E ++F
Sbjct: 869 LEAAASEKQRVEELQRSRRRYMEENNLEHIPKFF 902
>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
[Homo sapiens]
Length = 934
Score = 282 bits (722), Expect = 4e-76
Identities = 171/454 (37%), Positives = 236/454 (51%), Gaps = 59/454 (12%)
Query: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGI------Q 58
EFFDA S +SS E S+ ++ + D + N + R +
Sbjct: 494 EFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRN 553
Query: 59 KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 118
R LPAP S+ ++W IL+ +G +LSK++MP+ NEPL+ LQ + E ME+ L+
Sbjct: 554 GRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLD 613
Query: 119 RASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVS 177
+AS P ERM VAAFAVS S + R G KPFNP+LGETYE IRED GFRF SEQVS
Sbjct: 614 KASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVS 673
Query: 178 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 237
HHPPISA H E N F+F I K KFWGKS+E P GT+ + L K+ + Y W T
Sbjct: 674 HHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTT 731
Query: 238 CVHNVIIGKLWIEQYGTVEILNHRTG-HKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF 296
C+HN++ G+ WIE YG V I N ++ C L F + +++V+G + D+ K ++
Sbjct: 732 CIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVY 791
Query: 297 MIYGKWTECLW-GIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
++GKW E L+ G+ P
Sbjct: 792 RLFGKWHEGLYCGVAP-------------------------------------------- 807
Query: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
+K +WR + P N Y FT F + LNEL+ ++ LPPTD R RPD R +E GN
Sbjct: 808 ---SAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGN 864
Query: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWF 449
++ A+ EK+R+EE QR RR + E ++F
Sbjct: 865 LEAAASEKQRVEELQRSRRRYMEENNLEHIPKFF 898
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 282 bits (722), Expect = 4e-76
Identities = 183/499 (36%), Positives = 263/499 (52%), Gaps = 69/499 (13%)
Query: 4 EEEFFDAVTGFDSDNSSGEFSEANQKVTGM---IDLDTSKNNRIGKTGERPSQENGIQKH 60
E EFFDA + G ++G I LD +++ +T + +
Sbjct: 356 ENEFFDAPEIITMPENLGH-KRTGSNISGASSDISLDEQYKHQLEETKK---------EK 405
Query: 61 RTSLP-APMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHR 119
RT +P P +S ++W+I+K C+G ELSKI MP+ FNEPLS LQR+TE +E+ L+ R
Sbjct: 406 RTRIPYKPNYS---LNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDR 462
Query: 120 ASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIR-EDLGFRFISEQVSH 178
A+ LE++ VAAF VS+ ++ RT KPFNPLLGET+EL R E+ G+R + EQVSH
Sbjct: 463 AAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSH 522
Query: 179 HPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCC 238
HPP +A H+E N + I KF GK + P GTI YTW T
Sbjct: 523 HPPAAAHHAESKN-GWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTT 581
Query: 239 VHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKEL-HKVEGHIQDKNKKKLFM 297
VHN+I+GKLWI+Q G ++I+NH+TG KC L F P F +++ KV G + D + K F
Sbjct: 582 VHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFA 641
Query: 298 IYGKWTECL--WGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
+ G W E + + + PV E+ +RG ++++
Sbjct: 642 LLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRV----------------------- 678
Query: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
+LW+ N P N+ MY F+ ++LN E+G PTD RLRPD R MENG
Sbjct: 679 ------MLWKRNPLPKNAENMYYFSELALTLNAWESGTA----PTDSRLRPDQRLMENGR 728
Query: 416 MDLASQEKERLEEKQREARRERAKEEAE----------WQTRWFYPGNNPYTGTPDWLYA 465
D A+ EK+RLEEKQR +R++R E + ++ WF +P T +Y
Sbjct: 729 WDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTPYDPYKALWFERKKDPVTKELTHIYR 788
Query: 466 GDYFE----RNFSDCPDIY 480
G+Y+E +++S CPDI+
Sbjct: 789 GEYWECKEKQDWSSCPDIF 807
>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
Length = 842
Score = 278 bits (712), Expect = 6e-75
Identities = 172/454 (37%), Positives = 240/454 (52%), Gaps = 59/454 (12%)
Query: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMID-------LDTSKNNRIGKTGERPSQENGI 57
EFFDA S +SS E SE + T I LD R K G P + G
Sbjct: 402 EFFDACEVLLSASSSENEGSEEEESCTSEITTSLSEEMLDLRGAERCQKGGCVPGRPMGP 461
Query: 58 QKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117
+ R LPA +D S+W IL+ +G +LSK++MP+ NEPL+ LQR+ E +E+ L+
Sbjct: 462 PRRRC-LPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLL 520
Query: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176
+AS P ERM +AAFAVSA +S + R G KPFNP+LGETYE R D GFRFISEQV
Sbjct: 521 DQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQV 580
Query: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236
SHHPPISA H+E N F F + K KFWGKS+E P GT+ + L + + + W T
Sbjct: 581 SHHPPISACHAESEN--FAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVT 638
Query: 237 CCVHNVIIGKLWIEQYGTVEILNHR-TGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295
C+HNV+ G+ WIE YG V I N + + C + F + +H+V+G + ++ + L
Sbjct: 639 SCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVL 698
Query: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
++GKW E L+ RG
Sbjct: 699 HRLFGKWHEGLY---------------RGP------------------------------ 713
Query: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
PG + +W+ N+ PP+ + + FT F + LNEL ++++LP TD RLRPD R +E GN
Sbjct: 714 -TPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLRPDQRYLEEGN 772
Query: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWF 449
+ A +K R+E+ QR+ R+ + Q R+F
Sbjct: 773 IQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFF 806
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 272 bits (695), Expect = 6e-73
Identities = 181/502 (36%), Positives = 254/502 (50%), Gaps = 59/502 (11%)
Query: 4 EEEFFDAVTGFDSD----NSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQK 59
+ E+FDA+ S + E S + TG +D S + + + + K
Sbjct: 449 DTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVK 508
Query: 60 HRTSLP-APMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 118
R +P P +S ++W+I+K C+G ELS+I MP+ FNEPLS LQR+TE +E+ +L+
Sbjct: 509 RRVRIPNKPNYS---LNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLD 565
Query: 119 RASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIR-EDLGFRFISEQVS 177
+A +E+M VAAF+VS+ ++ R KPFNP+LGET+EL R +D+G R + EQVS
Sbjct: 566 KAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVS 625
Query: 178 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 237
HHPP SA H H + I KF GK + P G I LE Y W T
Sbjct: 626 HHPP-SAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTS 684
Query: 238 CVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKE-LHKVEGHIQDKNKKKLF 296
VHN+I+GKLWI+Q G +EI+NH+T +C L F P F KE KV G + D K +
Sbjct: 685 TVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHY 744
Query: 297 MIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQV 356
++ G W E + +K+ S + S Q+TV
Sbjct: 745 VLSGSWDE---------------------QMECSKVMHSSPSSPSSDG-----KQKTVYQ 778
Query: 357 IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNM 416
+KLLW+ P N+ MY F+ ++LNE E G + PTD RLRPD R ME G
Sbjct: 779 TLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRW 834
Query: 417 DLASQEKERLEEKQREARR--------------ERAKEEAEWQTRWFYPGNNPYTGTPDW 462
D A+ EK+RLEEKQR +RR E KE + WF +P TG
Sbjct: 835 DEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMAC 894
Query: 463 LYAGDYFE----RNFSDCPDIY 480
+Y G Y+E +++ CP+I+
Sbjct: 895 VYKGGYWEAKEKQDWHMCPNIF 916
>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
[Homo sapiens]
Length = 820
Score = 268 bits (685), Expect = 8e-72
Identities = 172/475 (36%), Positives = 246/475 (51%), Gaps = 63/475 (13%)
Query: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGER----PSQENGIQ-- 58
EFFDA S +SS E S+ + V+ + D + N ER P ++G +
Sbjct: 383 EFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 442
Query: 59 -KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117
+ RT LPAP S S+ S+W IL+ +G +LSK+ MP+ NEPL+ LQR+ E +E+ L+
Sbjct: 443 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 502
Query: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176
+A+ P PLERM VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQV
Sbjct: 503 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 562
Query: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236
SHHPPISA H+E N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 563 SHHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVT 620
Query: 237 CCVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295
C+HN++ G+ WIE YG + I N H C ++F + H++EG + D++ K +
Sbjct: 621 SCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAV 680
Query: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
++GKW E ++ G + + V P+ + Q
Sbjct: 681 HRLFGKWHESIYC--------------------------GGGSSSACVWRANPMPKGYEQ 714
Query: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
++ +N P+S + LPPTD R RPD R +E GN
Sbjct: 715 YYSFTQFALELNEMDPSSKSL--------------------LPPTDTRFRPDQRFLEEGN 754
Query: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 470
++ A +K+R+E+ QRE RR + E Q R+F ++ W+ G Y E
Sbjct: 755 LEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 804
>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
[Homo sapiens]
Length = 851
Score = 268 bits (685), Expect = 8e-72
Identities = 172/475 (36%), Positives = 246/475 (51%), Gaps = 63/475 (13%)
Query: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGER----PSQENGIQ-- 58
EFFDA S +SS E S+ + V+ + D + N ER P ++G +
Sbjct: 414 EFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 473
Query: 59 -KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117
+ RT LPAP S S+ S+W IL+ +G +LSK+ MP+ NEPL+ LQR+ E +E+ L+
Sbjct: 474 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 533
Query: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176
+A+ P PLERM VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQV
Sbjct: 534 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 593
Query: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236
SHHPPISA H+E N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 594 SHHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVT 651
Query: 237 CCVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295
C+HN++ G+ WIE YG + I N H C ++F + H++EG + D++ K +
Sbjct: 652 SCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAV 711
Query: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
++GKW E ++ G + + V P+ + Q
Sbjct: 712 HRLFGKWHESIYC--------------------------GGGSSSACVWRANPMPKGYEQ 745
Query: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
++ +N P+S + LPPTD R RPD R +E GN
Sbjct: 746 YYSFTQFALELNEMDPSSKSL--------------------LPPTDTRFRPDQRFLEEGN 785
Query: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 470
++ A +K+R+E+ QRE RR + E Q R+F ++ W+ G Y E
Sbjct: 786 LEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 835
>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
[Homo sapiens]
Length = 856
Score = 268 bits (685), Expect = 8e-72
Identities = 172/475 (36%), Positives = 246/475 (51%), Gaps = 63/475 (13%)
Query: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGER----PSQENGIQ-- 58
EFFDA S +SS E S+ + V+ + D + N ER P ++G +
Sbjct: 419 EFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 478
Query: 59 -KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117
+ RT LPAP S S+ S+W IL+ +G +LSK+ MP+ NEPL+ LQR+ E +E+ L+
Sbjct: 479 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 538
Query: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176
+A+ P PLERM VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQV
Sbjct: 539 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 598
Query: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236
SHHPPISA H+E N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 599 SHHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVT 656
Query: 237 CCVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295
C+HN++ G+ WIE YG + I N H C ++F + H++EG + D++ K +
Sbjct: 657 SCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAV 716
Query: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
++GKW E ++ G + + V P+ + Q
Sbjct: 717 HRLFGKWHESIYC--------------------------GGGSSSACVWRANPMPKGYEQ 750
Query: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
++ +N P+S + LPPTD R RPD R +E GN
Sbjct: 751 YYSFTQFALELNEMDPSSKSL--------------------LPPTDTRFRPDQRFLEEGN 790
Query: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 470
++ A +K+R+E+ QRE RR + E Q R+F ++ W+ G Y E
Sbjct: 791 LEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 840
>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
[Homo sapiens]
Length = 887
Score = 268 bits (685), Expect = 8e-72
Identities = 172/475 (36%), Positives = 246/475 (51%), Gaps = 63/475 (13%)
Query: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGER----PSQENGIQ-- 58
EFFDA S +SS E S+ + V+ + D + N ER P ++G +
Sbjct: 450 EFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 509
Query: 59 -KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117
+ RT LPAP S S+ S+W IL+ +G +LSK+ MP+ NEPL+ LQR+ E +E+ L+
Sbjct: 510 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 569
Query: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176
+A+ P PLERM VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQV
Sbjct: 570 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 629
Query: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236
SHHPPISA H+E N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 630 SHHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVT 687
Query: 237 CCVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295
C+HN++ G+ WIE YG + I N H C ++F + H++EG + D++ K +
Sbjct: 688 SCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAV 747
Query: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
++GKW E ++ G + + V P+ + Q
Sbjct: 748 HRLFGKWHESIYC--------------------------GGGSSSACVWRANPMPKGYEQ 781
Query: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
++ +N P+S + LPPTD R RPD R +E GN
Sbjct: 782 YYSFTQFALELNEMDPSSKSL--------------------LPPTDTRFRPDQRFLEEGN 821
Query: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 470
++ A +K+R+E+ QRE RR + E Q R+F ++ W+ G Y E
Sbjct: 822 LEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 871
>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
[Homo sapiens]
Length = 879
Score = 134 bits (337), Expect = 2e-31
Identities = 109/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)
Query: 76 VWTILKKC-VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVA 134
+WT+LK+ G++LS++ +P EP SFL ++++Y H L+ RA+ + RM+ V
Sbjct: 371 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 430
Query: 135 AFAVSAVASQWERTGKPFNPLLGETYELI----REDLGFRFISEQVSHHPPISAFHSEGL 190
+ +S + + KP+NP+LGET+ + D +I+EQVSHHPP+SAFH
Sbjct: 431 RWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNR 490
Query: 191 NHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIE 250
F GSI K +F+G S+ A G TL L E YT T P ++ G + +E
Sbjct: 491 KDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLE 550
Query: 251 QYGTVEILNHRTGHKCVLHFKPCGLFG--KELHKVEGHIQDKNKKKLFMIYGKWTECLWG 308
G V I + + L FK FG ++++ G I ++ L + G W
Sbjct: 551 LGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR---- 605
Query: 309 IDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINT 368
+ F K+E G S L W
Sbjct: 606 ------DVFIKEEGSG----------------------------------SSALFW---- 621
Query: 369 RPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDI-RGMENGNMDLASQEKERLE 427
P + TV L E +T +E RL + R + G+ A+QEK LE
Sbjct: 622 TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFALE 674
Query: 428 EKQREARRERAKEEAEWQTRWFY 450
E QR+ RER + W+ + F+
Sbjct: 675 EAQRQRARERQESLMPWKPQLFH 697
>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 134 bits (337), Expect = 2e-31
Identities = 109/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)
Query: 76 VWTILKKC-VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVA 134
+WT+LK+ G++LS++ +P EP SFL ++++Y H L+ RA+ + RM+ V
Sbjct: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
Query: 135 AFAVSAVASQWERTGKPFNPLLGETYELI----REDLGFRFISEQVSHHPPISAFHSEGL 190
+ +S + + KP+NP+LGET+ + D +I+EQVSHHPP+SAFH
Sbjct: 363 RWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNR 422
Query: 191 NHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIE 250
F GSI K +F+G S+ A G TL L E YT T P ++ G + +E
Sbjct: 423 KDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLE 482
Query: 251 QYGTVEILNHRTGHKCVLHFKPCGLFG--KELHKVEGHIQDKNKKKLFMIYGKWTECLWG 308
G V I + + L FK FG ++++ G I ++ L + G W
Sbjct: 483 LGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR---- 537
Query: 309 IDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINT 368
+ F K+E G S L W
Sbjct: 538 ------DVFIKEEGSG----------------------------------SSALFW---- 553
Query: 369 RPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDI-RGMENGNMDLASQEKERLE 427
P + TV L E +T +E RL + R + G+ A+QEK LE
Sbjct: 554 TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFALE 606
Query: 428 EKQREARRERAKEEAEWQTRWFY 450
E QR+ RER + W+ + F+
Sbjct: 607 EAQRQRARERQESLMPWKPQLFH 629
>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 134 bits (337), Expect = 2e-31
Identities = 109/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)
Query: 76 VWTILKKC-VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVA 134
+WT+LK+ G++LS++ +P EP SFL ++++Y H L+ RA+ + RM+ V
Sbjct: 303 MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVL 362
Query: 135 AFAVSAVASQWERTGKPFNPLLGETYELI----REDLGFRFISEQVSHHPPISAFHSEGL 190
+ +S + + KP+NP+LGET+ + D +I+EQVSHHPP+SAFH
Sbjct: 363 RWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNR 422
Query: 191 NHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIE 250
F GSI K +F+G S+ A G TL L E YT T P ++ G + +E
Sbjct: 423 KDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLE 482
Query: 251 QYGTVEILNHRTGHKCVLHFKPCGLFG--KELHKVEGHIQDKNKKKLFMIYGKWTECLWG 308
G V I + + L FK FG ++++ G I ++ L + G W
Sbjct: 483 LGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR---- 537
Query: 309 IDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINT 368
+ F K+E G S L W
Sbjct: 538 ------DVFIKEEGSG----------------------------------SSALFW---- 553
Query: 369 RPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDI-RGMENGNMDLASQEKERLE 427
P + TV L E +T +E RL + R + G+ A+QEK LE
Sbjct: 554 TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFALE 606
Query: 428 EKQREARRERAKEEAEWQTRWFY 450
E QR+ RER + W+ + F+
Sbjct: 607 EAQRQRARERQESLMPWKPQLFH 629
>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
[Homo sapiens]
Length = 847
Score = 133 bits (335), Expect = 3e-31
Identities = 84/269 (31%), Positives = 134/269 (49%), Gaps = 20/269 (7%)
Query: 41 NNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKC-VGLELSKITMPIAFNE 99
+ +G+ GE SQ + + SL +WT+LK+ G++LSK+ +P E
Sbjct: 342 HEELGEAGEA-SQTETVSEENKSL-----------IWTLLKQVRPGMDLSKVVLPTFILE 389
Query: 100 PLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGET 159
P SFL ++++Y H + A+ + P R++ V + +S + + KP+NP+LGET
Sbjct: 390 PRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGET 449
Query: 160 YELI----REDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEP 215
+ + R + +I+EQVSHHPPISAF+ F GSI K KF+G S+ A
Sbjct: 450 FRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAIL 509
Query: 216 RGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGL 275
G L L E Y T P ++ G + +E GTV I +TG+ +L FK
Sbjct: 510 EGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPF 569
Query: 276 FGKE--LHKVEGHIQDKNKKKLFMIYGKW 302
G ++++ G ++ K+ L + G W
Sbjct: 570 LGSSDCVNQISGKLK-LGKEVLATLEGHW 597
Score = 34.7 bits (78), Expect = 0.20
Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 4/46 (8%)
Query: 419 ASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLY 464
A+QEK LEE QR+A R+R + EW + F +P TG +W Y
Sbjct: 660 ATQEKYVLEEAQRQAARDRKTKNEEWSCKLF--ELDPLTG--EWHY 701
>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
Length = 889
Score = 133 bits (335), Expect = 3e-31
Identities = 84/269 (31%), Positives = 134/269 (49%), Gaps = 20/269 (7%)
Query: 41 NNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKC-VGLELSKITMPIAFNE 99
+ +G+ GE SQ + + SL +WT+LK+ G++LSK+ +P E
Sbjct: 384 HEELGEAGEA-SQTETVSEENKSL-----------IWTLLKQVRPGMDLSKVVLPTFILE 431
Query: 100 PLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGET 159
P SFL ++++Y H + A+ + P R++ V + +S + + KP+NP+LGET
Sbjct: 432 PRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGET 491
Query: 160 YELI----REDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEP 215
+ + R + +I+EQVSHHPPISAF+ F GSI K KF+G S+ A
Sbjct: 492 FRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAIL 551
Query: 216 RGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGL 275
G L L E Y T P ++ G + +E GTV I +TG+ +L FK
Sbjct: 552 EGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPF 611
Query: 276 FGKE--LHKVEGHIQDKNKKKLFMIYGKW 302
G ++++ G ++ K+ L + G W
Sbjct: 612 LGSSDCVNQISGKLK-LGKEVLATLEGHW 639
Score = 34.7 bits (78), Expect = 0.20
Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 4/46 (8%)
Query: 419 ASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLY 464
A+QEK LEE QR+A R+R + EW + F +P TG +W Y
Sbjct: 702 ATQEKYVLEEAQRQAARDRKTKNEEWSCKLF--ELDPLTG--EWHY 743
>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
Length = 736
Score = 109 bits (273), Expect = 5e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
Query: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 444 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 503
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 504 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 563
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 564 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 622
Query: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 623 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 658
Query: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
+ S ++ +F + + +++ E
Sbjct: 659 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 686
Query: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
K RLEE+QR RER ++E +W+TR F+
Sbjct: 687 --AKHRLEERQRAEARERKEKEIQWETRLFH 715
>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
sapiens]
Length = 746
Score = 109 bits (273), Expect = 5e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 394 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 453
Query: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 454 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 513
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 514 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 573
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 574 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 632
Query: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 633 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 668
Query: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
+ S ++ +F + + +++ E
Sbjct: 669 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 696
Query: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
K RLEE+QR RER ++E +W+TR F+
Sbjct: 697 --AKHRLEERQRAEARERKEKEIQWETRLFH 725
>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
sapiens]
Length = 723
Score = 109 bits (273), Expect = 5e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 371 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 430
Query: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 431 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 490
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 491 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 550
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 551 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 609
Query: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 610 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 645
Query: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
+ S ++ +F + + +++ E
Sbjct: 646 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 673
Query: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
K RLEE+QR RER ++E +W+TR F+
Sbjct: 674 --AKHRLEERQRAEARERKEKEIQWETRLFH 702
>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
sapiens]
Length = 626
Score = 109 bits (273), Expect = 5e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 274 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 333
Query: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 334 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 393
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 394 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 453
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 454 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 512
Query: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 513 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 548
Query: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
+ S ++ +F + + +++ E
Sbjct: 549 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 576
Query: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
K RLEE+QR RER ++E +W+TR F+
Sbjct: 577 --AKHRLEERQRAEARERKEKEIQWETRLFH 605
>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
sapiens]
Length = 571
Score = 109 bits (273), Expect = 5e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 219 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 278
Query: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 279 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 338
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 339 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 398
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 399 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 457
Query: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 458 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 493
Query: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
+ S ++ +F + + +++ E
Sbjct: 494 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 521
Query: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
K RLEE+QR RER ++E +W+TR F+
Sbjct: 522 --AKHRLEERQRAEARERKEKEIQWETRLFH 550
>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 109 bits (273), Expect = 5e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 206 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 265
Query: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 266 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 325
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 326 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 385
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 386 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 444
Query: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 445 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 480
Query: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
+ S ++ +F + + +++ E
Sbjct: 481 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 508
Query: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
K RLEE+QR RER ++E +W+TR F+
Sbjct: 509 --AKHRLEERQRAEARERKEKEIQWETRLFH 537
>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 109 bits (273), Expect = 5e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 206 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 265
Query: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 266 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 325
Query: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 326 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 385
Query: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 386 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 444
Query: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 445 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 480
Query: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
+ S ++ +F + + +++ E
Sbjct: 481 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 508
Query: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
K RLEE+QR RER ++E +W+TR F+
Sbjct: 509 --AKHRLEERQRAEARERKEKEIQWETRLFH 537
>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
sapiens]
Length = 764
Score = 93.6 bits (231), Expect = 4e-19
Identities = 65/256 (25%), Positives = 110/256 (42%), Gaps = 34/256 (13%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAV-- 141
+G++L+K+ +P E S L+ ++M H L+ + P ER+ + ++A
Sbjct: 409 LGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHE 468
Query: 142 ASQWERTGKPFNPLLGETYELIRE------------------------------DLGFRF 171
+ KP+NP++GET+ E RF
Sbjct: 469 GRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLRF 528
Query: 172 ISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYT 231
++EQVSHHPPIS F+ E + ++ K KF G SV G L LL+H E Y
Sbjct: 529 VAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYV 588
Query: 232 WTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKN 291
+T P+ +++ W+E G V I +TG+ + F +G ++H+V ++
Sbjct: 589 FTLPSAYARSILTIP-WVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNP 647
Query: 292 KKKLF-MIYGKWTECL 306
+ +G+W L
Sbjct: 648 TNTIVCKAHGEWNGTL 663
Score = 35.8 bits (81), Expect = 0.088
Identities = 15/41 (36%), Positives = 25/41 (60%)
Query: 409 RGMENGNMDLASQEKERLEEKQREARRERAKEEAEWQTRWF 449
R + G++D A+++K LEEKQR R+R W+ ++F
Sbjct: 707 RYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYF 747
>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
Length = 747
Score = 88.6 bits (218), Expect = 1e-17
Identities = 64/262 (24%), Positives = 111/262 (42%), Gaps = 40/262 (15%)
Query: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAV-- 141
+G++L+++ +P E S L+ ++M H L + +RM + +++
Sbjct: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
Query: 142 ASQWERTGKPFNPLLGETYE----------------------------LIREDLG----- 168
+ KP+NP++GET+ L E L
Sbjct: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
Query: 169 ---FRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLK 225
RF++EQVSHHPP+S F++E + ++ K KF G S+ G L LL+
Sbjct: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
Query: 226 HNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEG 285
H E YT++ P C I+ W+E G V + +TG+ + F +G +LH+V
Sbjct: 559 HGEEYTFSLP-CAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTA 617
Query: 286 HIQDK-NKKKLFMIYGKWTECL 306
++ + + G+W L
Sbjct: 618 EVKHNITNTVVCRVQGEWNSVL 639
Score = 34.7 bits (78), Expect = 0.20
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 393 MEKTLPPTDCRLRPDIR-GMENGNMDLASQEKERLEEKQREARRERAKEEAEWQTRWF 449
+EK P RL ++ + +D A++ K LEE+QR R R + W+T++F
Sbjct: 666 LEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 38.5 bits (88), Expect = 0.014
Identities = 15/36 (41%), Positives = 25/36 (69%)
Query: 412 ENGNMDLASQEKERLEEKQREARRERAKEEAEWQTR 447
E GNM+L + + +E++QREA R+ KE+ EW+ +
Sbjct: 372 ERGNMELEKRRQALMEQQQREAERKAQKEKEEWERK 407
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 38.5 bits (88), Expect = 0.014
Identities = 15/36 (41%), Positives = 25/36 (69%)
Query: 412 ENGNMDLASQEKERLEEKQREARRERAKEEAEWQTR 447
E GNM+L + + +E++QREA R+ KE+ EW+ +
Sbjct: 372 ERGNMELEKRRQALMEQQQREAERKAQKEKEEWERK 407
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 38.5 bits (88), Expect = 0.014
Identities = 15/36 (41%), Positives = 25/36 (69%)
Query: 412 ENGNMDLASQEKERLEEKQREARRERAKEEAEWQTR 447
E GNM+L + + +E++QREA R+ KE+ EW+ +
Sbjct: 372 ERGNMELEKRRQALMEQQQREAERKAQKEKEEWERK 407
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,320,710
Number of Sequences: 37866
Number of extensions: 952118
Number of successful extensions: 4774
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 4358
Number of HSP's gapped (non-prelim): 358
length of query: 480
length of database: 18,247,518
effective HSP length: 106
effective length of query: 374
effective length of database: 14,233,722
effective search space: 5323412028
effective search space used: 5323412028
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.