Guide to the Human Genome
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Search of human proteins with 21450729

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21450729 hypothetical protein LOC219833 [Homo sapiens]
         (145 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21450729 hypothetical protein LOC219833 [Homo sapiens]             301   1e-82
gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]            34   0.038
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]            31   0.32 
gi|4502119 amine oxidase, copper containing 3 precursor [Homo sa...    31   0.32 
gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo s...    29   1.2  
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    28   2.1  
gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens]    28   2.1  
gi|156938343 talin 2 [Homo sapiens]                                    28   2.7  
gi|55741647 hypothetical protein LOC158405 [Homo sapiens]              28   2.7  
gi|22538442 cathepsin Z preproprotein [Homo sapiens]                   28   3.5  
gi|4502841 carbohydrate (keratan sulfate Gal-6) sulfotransferase...    27   4.6  
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...    27   4.6  
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...    27   4.6  
gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s...    27   4.6  
gi|83367077 mucin 16 [Homo sapiens]                                    27   6.0  
gi|239757605 PREDICTED: hypothetical protein [Homo sapiens]            27   6.0  
gi|239752107 PREDICTED: hypothetical protein [Homo sapiens]            27   6.0  
gi|239746611 PREDICTED: hypothetical protein XP_002343792 [Homo ...    27   6.0  
gi|4557467 excision repair cross-complementing rodent repair def...    27   6.0  
gi|120952764 mastermind-like domain containing 1 [Homo sapiens]        27   6.0  
gi|27735129 hypothetical protein LOC148345 [Homo sapiens]              27   7.9  
gi|30410035 late cornified envelope 5A [Homo sapiens]                  27   7.9  
gi|55743075 angio-associated, migratory cell protein [Homo sapiens]    27   7.9  

>gi|21450729 hypothetical protein LOC219833 [Homo sapiens]
          Length = 145

 Score =  301 bits (772), Expect = 1e-82
 Identities = 145/145 (100%), Positives = 145/145 (100%)

Query: 1   MLTRLVLSAHLSSTTSPPWTHAAISWELDNVLMPSPRIWPQVTPTGRSASVRSEGNTSSL 60
           MLTRLVLSAHLSSTTSPPWTHAAISWELDNVLMPSPRIWPQVTPTGRSASVRSEGNTSSL
Sbjct: 1   MLTRLVLSAHLSSTTSPPWTHAAISWELDNVLMPSPRIWPQVTPTGRSASVRSEGNTSSL 60

Query: 61  WNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNITCQSSGQQRQAARQEEENSIC 120
           WNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNITCQSSGQQRQAARQEEENSIC
Sbjct: 61  WNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNITCQSSGQQRQAARQEEENSIC 120

Query: 121 KAHDSREGRLGYPLSAHQPGSGGPN 145
           KAHDSREGRLGYPLSAHQPGSGGPN
Sbjct: 121 KAHDSREGRLGYPLSAHQPGSGGPN 145


>gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 34.3 bits (77), Expect = 0.038
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 41  QVTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNIT 100
           Q + T  + S +S G +S+  N+ + +     ++ TC S  SS   +  C C  S T+ T
Sbjct: 32  QSSQTSSTCSCQSSGTSSTSCNWQSSR-----ISSTC-SCQSSGTSSTSCSCQSSETSST 85

Query: 101 --CQSSGQQRQAARQE--EENSICKAHDSR 126
             CQSSG    +   +    +S C+   SR
Sbjct: 86  CSCQSSGTSSTSCSWQFSRTSSTCRCQSSR 115



 Score = 30.4 bits (67), Expect = 0.55
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 10/90 (11%)

Query: 41  QVTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNIT 100
           Q + T  + S +S G +S+ ++  +        + TC S  SS   +  C C  S T+ T
Sbjct: 182 QSSRTSSTCSCQSSGTSSTSYSCQSSG-----TSSTC-SCQSSGTSSTSCSCQSSGTSST 235

Query: 101 --CQSSGQQRQAA--RQEEENSICKAHDSR 126
             CQSSG    +   +    +S C    SR
Sbjct: 236 CSCQSSGTSSTSCSWQSSRTSSTCSCQSSR 265



 Score = 29.6 bits (65), Expect = 0.93
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 10/90 (11%)

Query: 41  QVTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNIT 100
           Q + T  + S +S G +S+  ++ + +      + TC S  SS   +  C C  S T+ T
Sbjct: 228 QSSGTSSTCSCQSSGTSSTSCSWQSSR-----TSSTC-SCQSSRTSSTSCSCQSSGTSST 281

Query: 101 --CQSSGQQRQ--AARQEEENSICKAHDSR 126
             CQSSG      + +    +S C    SR
Sbjct: 282 CSCQSSGTSSTSCSCQSSRTSSTCSCQFSR 311


>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 31.2 bits (69), Expect = 0.32
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 10/90 (11%)

Query: 41  QVTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNIT 100
           Q + T  + S +S G +S+  N+ + +      + TC S  SS   +  C C  S T+ T
Sbjct: 32  QSSQTSSTCSCQSSGTSSTSCNWQSSR-----TSSTC-SCQSSGTSSTSCSCQSSETSST 85

Query: 101 --CQSSGQQRQAARQE--EENSICKAHDSR 126
             CQSSG    +   +    +S C    SR
Sbjct: 86  CSCQSSGTSSTSCSWQFSRTSSTCCCQSSR 115



 Score = 30.0 bits (66), Expect = 0.71
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 10/90 (11%)

Query: 41  QVTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNIT 100
           Q + T  + S +S G +S+  ++ + +      + TC S  SS   +  C C  S T+ T
Sbjct: 228 QSSGTSSTCSCQSSGTSSTSCSWQSSR-----TSSTC-SCQSSGTSSTSCSCQSSGTSST 281

Query: 101 --CQSSGQQRQ--AARQEEENSICKAHDSR 126
             CQSSG      + +    +S C    SR
Sbjct: 282 CSCQSSGTSSTSCSCQSSRTSSTCSCQFSR 311



 Score = 28.5 bits (62), Expect = 2.1
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 10/89 (11%)

Query: 41  QVTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSATNIT 100
           Q + T  + S +S G +S+ ++  +        + TC S  SS   +  C C  S T+ T
Sbjct: 182 QSSRTSSTCSCQSSGTSSTSYSCQSSG-----TSSTC-SCQSSGTSSTSCSCQSSGTSST 235

Query: 101 --CQSSGQQRQAA--RQEEENSICKAHDS 125
             CQSSG    +   +    +S C    S
Sbjct: 236 CSCQSSGTSSTSCSWQSSRTSSTCSCQSS 264


>gi|4502119 amine oxidase, copper containing 3 precursor [Homo
           sapiens]
          Length = 763

 Score = 31.2 bits (69), Expect = 0.32
 Identities = 17/42 (40%), Positives = 20/42 (47%)

Query: 25  SWELDNVLMPSPRIWPQVTPTGRSASVRSEGNTSSLWNFSAG 66
           SW L + + P P    Q  P G   SV+     SSLW FS G
Sbjct: 299 SWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFG 340


>gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo
           sapiens]
          Length = 1050

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 8   SAHLSSTTSPPWTHAAISWELDNVLMPSPRIWPQVTPTGRSASVRSEGNTSSL 60
           +A LS  T  PW    +    +N L   P  W     TGRS   R  GNT+SL
Sbjct: 284 TAELSKPTVQPWIAPPMPRAKENELQAGP--WN----TGRSLEHRPRGNTASL 330


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 28.5 bits (62), Expect = 2.1
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 103 SSGQQRQAARQEEENSICKAHDSREGRLGYPLSAHQPGSGG 143
           S  ++R+   QEEE    K    RE  LG P S+ +  +GG
Sbjct: 872 SDSEKRRPEEQEEEPQPRKPGTRRERTLGAPASSERSAAGG 912


>gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens]
          Length = 454

 Score = 28.5 bits (62), Expect = 2.1
 Identities = 12/28 (42%), Positives = 18/28 (64%)

Query: 53  SEGNTSSLWNFSAGQDVHAIVTRTCESV 80
           S+  ++ LW+ S GQ V+ I T TC +V
Sbjct: 165 SDDLSAKLWDVSTGQCVYGIQTHTCAAV 192


>gi|156938343 talin 2 [Homo sapiens]
          Length = 2542

 Score = 28.1 bits (61), Expect = 2.7
 Identities = 28/117 (23%), Positives = 44/117 (37%), Gaps = 21/117 (17%)

Query: 37  RIWPQVTPTGRSASVRSE-----GNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCG 91
           R+W Q         + S+       T+S+ N +AG       T              GC 
Sbjct: 532 RVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAV------------GCA 579

Query: 92  CVRSATNITCQSSGQQRQAARQEEE----NSICKAHDSREGRLGYPLSAHQPGSGGP 144
               ++N+T  S G +  AA  ++E      + +A  +  G +   L A QP SG P
Sbjct: 580 ITTISSNLTEMSKGVKLLAALMDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEP 636


>gi|55741647 hypothetical protein LOC158405 [Homo sapiens]
          Length = 716

 Score = 28.1 bits (61), Expect = 2.7
 Identities = 11/27 (40%), Positives = 16/27 (59%)

Query: 53 SEGNTSSLWNFSAGQDVHAIVTRTCES 79
          S GN +++W  SAG   H  +T TC +
Sbjct: 40 SHGNLTAMWGCSAGHAYHWPLTATCRA 66


>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
          Length = 303

 Score = 27.7 bits (60), Expect = 3.5
 Identities = 19/77 (24%), Positives = 29/77 (37%), Gaps = 11/77 (14%)

Query: 10  HLSSTTSPPWTHAAISWELDNVLMPSPRIWP-------QVTPTGRSASVRSEGNTSSLWN 62
           H+       W HA+ S   D + +     WP        V   G + S    GN  S+W+
Sbjct: 84  HIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEG-GNDLSVWD 142

Query: 63  FSAGQDVHAIVTRTCES 79
           ++     H I   TC +
Sbjct: 143 YA---HQHGIPDETCNN 156


>gi|4502841 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
           [Homo sapiens]
          Length = 411

 Score = 27.3 bits (59), Expect = 4.6
 Identities = 11/37 (29%), Positives = 17/37 (45%)

Query: 50  SVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVY 86
           +VR+   T+  W F    D+ A     C+ VL+   Y
Sbjct: 349 TVRNSAATAEKWRFRLSYDIVAFAQNACQQVLAQLGY 385


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
           [Homo sapiens]
          Length = 1899

 Score = 27.3 bits (59), Expect = 4.6
 Identities = 27/107 (25%), Positives = 41/107 (38%), Gaps = 7/107 (6%)

Query: 38  IWPQVTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSAT 97
           ++  V  T  S S+   GNT  +        +  ++  T  SV   A+Y+ G G    A 
Sbjct: 803 VYSPVDGTRPSESIVVPGNTRMV-------HLERLIPDTLYSVNLVALYSDGEGNPSPAQ 855

Query: 98  NITCQSSGQQRQAARQEEENSICKAHDSREGRLGYPLSAHQPGSGGP 144
             T   SG +      E  NS+  A D  +G +      + P  G P
Sbjct: 856 GRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 902


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score = 27.3 bits (59), Expect = 4.6
 Identities = 27/107 (25%), Positives = 41/107 (38%), Gaps = 7/107 (6%)

Query: 38   IWPQVTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSAT 97
            ++  V  T  S S+   GNT  +        +  ++  T  SV   A+Y+ G G    A 
Sbjct: 1967 VYSPVDGTRPSESIVVPGNTRMV-------HLERLIPDTLYSVNLVALYSDGEGNPSPAQ 2019

Query: 98   NITCQSSGQQRQAARQEEENSICKAHDSREGRLGYPLSAHQPGSGGP 144
              T   SG +      E  NS+  A D  +G +      + P  G P
Sbjct: 2020 GRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 2066


>gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
           sapiens]
          Length = 731

 Score = 27.3 bits (59), Expect = 4.6
 Identities = 13/32 (40%), Positives = 17/32 (53%)

Query: 113 QEEENSICKAHDSREGRLGYPLSAHQPGSGGP 144
           +EEE        S  G  GYPL+  +PG+G P
Sbjct: 427 EEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEP 458


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 26.9 bits (58), Expect = 6.0
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 3     TRLVLSAHLSSTTSPPWTHAAISWELDNVLMPSPR-----------IWPQVTPTGRSASV 51
             +++  S   +STT P  TH+    E   +L   PR           ++PQV+ T  S ++
Sbjct: 11745 SQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTI 11804

Query: 52    RSEGNTSS 59
             R    TS+
Sbjct: 11805 RPGAETST 11812


>gi|239757605 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 115

 Score = 26.9 bits (58), Expect = 6.0
 Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 5/73 (6%)

Query: 26 WELDNVLMPSPRIWPQVTPTGRSASVRSEGNTSSLWNFSAGQDV---HAIVTRTCESVLS 82
          W L   L P  R WP+  P+G+    R      + W     + +     ++    +SV++
Sbjct: 5  WAL--ALTPRRRWWPRARPSGQPRPSRGSSLVPAPWRVRVDRCLPFRAVLIANAAQSVVA 62

Query: 83 SAVYTHGCGCVRS 95
          S   +    CV S
Sbjct: 63 SRHLSRAFTCVHS 75


>gi|239752107 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 115

 Score = 26.9 bits (58), Expect = 6.0
 Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 5/73 (6%)

Query: 26 WELDNVLMPSPRIWPQVTPTGRSASVRSEGNTSSLWNFSAGQDV---HAIVTRTCESVLS 82
          W L   L P  R WP+  P+G+    R      + W     + +     ++    +SV++
Sbjct: 5  WAL--ALTPRRRWWPRARPSGQPRPSRGSSLVPAPWRVRVDRCLPFRAVLIANAAQSVVA 62

Query: 83 SAVYTHGCGCVRS 95
          S   +    CV S
Sbjct: 63 SRHLSRAFTCVHS 75


>gi|239746611 PREDICTED: hypothetical protein XP_002343792 [Homo
          sapiens]
          Length = 115

 Score = 26.9 bits (58), Expect = 6.0
 Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 5/73 (6%)

Query: 26 WELDNVLMPSPRIWPQVTPTGRSASVRSEGNTSSLWNFSAGQDV---HAIVTRTCESVLS 82
          W L   L P  R WP+  P+G+    R      + W     + +     ++    +SV++
Sbjct: 5  WAL--ALTPRRRWWPRARPSGQPRPSRGSSLVPAPWRVRVDRCLPFRAVLIANAAQSVVA 62

Query: 83 SAVYTHGCGCVRS 95
          S   +    CV S
Sbjct: 63 SRHLSRAFTCVHS 75


>gi|4557467 excision repair cross-complementing rodent repair
           deficiency, complementation group 8 isoform 1 [Homo
           sapiens]
          Length = 396

 Score = 26.9 bits (58), Expect = 6.0
 Identities = 11/37 (29%), Positives = 16/37 (43%)

Query: 56  NTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGC 92
           N   LWN S G++      + C +      +T  CGC
Sbjct: 267 NRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGC 303


>gi|120952764 mastermind-like domain containing 1 [Homo sapiens]
          Length = 774

 Score = 26.9 bits (58), Expect = 6.0
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 86  YTHGCGCVRSATNITCQSSGQQRQAARQEEENSICKAHDSREGR-----LGYPLSAHQPG 140
           +T  C  +RS T  +   S QQ+Q  +Q++ N I K   S   +     +   +++  PG
Sbjct: 473 FTPQCSLIRSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPG 532

Query: 141 SGGP 144
           +  P
Sbjct: 533 ATEP 536


>gi|27735129 hypothetical protein LOC148345 [Homo sapiens]
          Length = 656

 Score = 26.6 bits (57), Expect = 7.9
 Identities = 15/44 (34%), Positives = 21/44 (47%)

Query: 11  LSSTTSPPWTHAAISWELDNVLMPSPRIWPQVTPTGRSASVRSE 54
           ++ T+SPP T     W    VL+PS          GR AS++ E
Sbjct: 582 VAHTSSPPSTQTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQE 625


>gi|30410035 late cornified envelope 5A [Homo sapiens]
          Length = 118

 Score = 26.6 bits (57), Expect = 7.9
 Identities = 18/66 (27%), Positives = 26/66 (39%)

Query: 77  CESVLSSAVYTHGCGCVRSATNITCQSSGQQRQAARQEEENSICKAHDSREGRLGYPLSA 136
           C   +SS   +   GC  S     C S  + RQ+ R+  ++S C    S +   G     
Sbjct: 44  CPPPVSSCCGSSSGGCCSSEGGGCCLSHHRPRQSLRRRPQSSSCCGSGSGQQSGGSSCCH 103

Query: 137 HQPGSG 142
              GSG
Sbjct: 104 SSGGSG 109


>gi|55743075 angio-associated, migratory cell protein [Homo sapiens]
          Length = 434

 Score = 26.6 bits (57), Expect = 7.9
 Identities = 11/37 (29%), Positives = 17/37 (45%)

Query: 36  PRIWPQVTPTGRSASVRSEGNTSSLWNFSAGQDVHAI 72
           P    +V P G+ A V  E  T  +W+   G  +H +
Sbjct: 217 PATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVL 253


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.124    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,290,332
Number of Sequences: 37866
Number of extensions: 256107
Number of successful extensions: 612
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 594
Number of HSP's gapped (non-prelim): 31
length of query: 145
length of database: 18,247,518
effective HSP length: 92
effective length of query: 53
effective length of database: 14,763,846
effective search space: 782483838
effective search space used: 782483838
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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