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Search of human proteins with 21450665
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21450665 coiled-coil domain containing 138 [Homo sapiens]
(665 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21450665 coiled-coil domain containing 138 [Homo sapiens] 1312 0.0
gi|31982906 cingulin-like 1 [Homo sapiens] 57 7e-08
gi|96975038 coiled-coil domain containing 100 [Homo sapiens] 51 3e-06
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 51 4e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 51 4e-06
gi|189217904 RPGRIP1-like isoform b [Homo sapiens] 51 4e-06
gi|118442834 RPGRIP1-like isoform a [Homo sapiens] 51 4e-06
gi|33946313 ninein isoform 4 [Homo sapiens] 51 4e-06
gi|33946321 ninein isoform 5 [Homo sapiens] 51 4e-06
gi|148536871 ninein isoform 1 [Homo sapiens] 51 4e-06
gi|148536869 ninein isoform 2 [Homo sapiens] 51 4e-06
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 50 5e-06
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 49 1e-05
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 48 3e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 48 3e-05
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 48 3e-05
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 47 6e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 47 6e-05
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 47 6e-05
gi|46852174 kinesin family member 3A [Homo sapiens] 46 1e-04
gi|31377634 guanylate binding protein 4 [Homo sapiens] 46 1e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 45 2e-04
gi|38569484 kinesin family member 21A [Homo sapiens] 45 2e-04
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 45 2e-04
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 45 2e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 45 3e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 45 3e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 45 3e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 45 3e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 44 4e-04
>gi|21450665 coiled-coil domain containing 138 [Homo sapiens]
Length = 665
Score = 1312 bits (3396), Expect = 0.0
Identities = 665/665 (100%), Positives = 665/665 (100%)
Query: 1 MEPRVVKPPGQDLVVESLKSRYGLGGSCPDEYDFSNFYQSKYKRRTLTSPGDLDIYSGDK 60
MEPRVVKPPGQDLVVESLKSRYGLGGSCPDEYDFSNFYQSKYKRRTLTSPGDLDIYSGDK
Sbjct: 1 MEPRVVKPPGQDLVVESLKSRYGLGGSCPDEYDFSNFYQSKYKRRTLTSPGDLDIYSGDK 60
Query: 61 VGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDSFHDLKKQETEEELIENDYRVSTSK 120
VGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDSFHDLKKQETEEELIENDYRVSTSK
Sbjct: 61 VGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDSFHDLKKQETEEELIENDYRVSTSK 120
Query: 121 ITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQI 180
ITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQI
Sbjct: 121 ITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQI 180
Query: 181 YDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRF 240
YDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRF
Sbjct: 181 YDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRF 240
Query: 241 QIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQA 300
QIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQA
Sbjct: 241 QIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQA 300
Query: 301 KRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELLTV 360
KRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELLTV
Sbjct: 301 KRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELLTV 360
Query: 361 FMDWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQLQWMPFVNIK 420
FMDWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQLQWMPFVNIK
Sbjct: 361 FMDWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQLQWMPFVNIK 420
Query: 421 LHEPFVKFIYWSLRQLDAGAQHSTMTSTLRRLGEDIFKGVVTKGIQDNSPQHSVENKPKT 480
LHEPFVKFIYWSLRQLDAGAQHSTMTSTLRRLGEDIFKGVVTKGIQDNSPQHSVENKPKT
Sbjct: 421 LHEPFVKFIYWSLRQLDAGAQHSTMTSTLRRLGEDIFKGVVTKGIQDNSPQHSVENKPKT 480
Query: 481 AAFFKSSNLPLRFLSTLIVLKTVTQADYLAQAFDSLCLDLKTEEGKTLFLEYQAVPVILS 540
AAFFKSSNLPLRFLSTLIVLKTVTQADYLAQAFDSLCLDLKTEEGKTLFLEYQAVPVILS
Sbjct: 481 AAFFKSSNLPLRFLSTLIVLKTVTQADYLAQAFDSLCLDLKTEEGKTLFLEYQAVPVILS 540
Query: 541 HLRISSKGLLSNVIDSLLQMTVESKSLQPFLEACSNSLFFRTCSVLLRAPKLDLQILEKL 600
HLRISSKGLLSNVIDSLLQMTVESKSLQPFLEACSNSLFFRTCSVLLRAPKLDLQILEKL
Sbjct: 541 HLRISSKGLLSNVIDSLLQMTVESKSLQPFLEACSNSLFFRTCSVLLRAPKLDLQILEKL 600
Query: 601 SIILQKLSKIKSNKKLFELFTIHLMLQEIQRTTNPEHAFLCINLNSTLFNLGLTKCNSLV 660
SIILQKLSKIKSNKKLFELFTIHLMLQEIQRTTNPEHAFLCINLNSTLFNLGLTKCNSLV
Sbjct: 601 SIILQKLSKIKSNKKLFELFTIHLMLQEIQRTTNPEHAFLCINLNSTLFNLGLTKCNSLV 660
Query: 661 SSASP 665
SSASP
Sbjct: 661 SSASP 665
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 56.6 bits (135), Expect = 7e-08
Identities = 51/190 (26%), Positives = 97/190 (51%), Gaps = 19/190 (10%)
Query: 173 LPHQISQIYDELFQIHLKLQCETAAQ-QKFAEELQKRERFLL---EREQLLFRHENALSK 228
L Q+S+++DEL E A ++ + Q + L+ E+E LL + E L+
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 229 IKG-VEEEVLTRFQI---IKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKK 284
+KG ++EEV + Q +KEQ+DAE++ L E ++E K + L S + ++ +
Sbjct: 763 LKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEM 822
Query: 285 QLNEASEENRKIDIQAKRVQARLDNLQRKYEFM---------TIQRLKGSSHAVHE--MK 333
++ EEN K+ +++ ++ R+ LQR+ E + T+++ +G + E +
Sbjct: 823 RVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVH 882
Query: 334 SLKQEKAPVS 343
+ K+EK VS
Sbjct: 883 ARKEEKEAVS 892
>gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
Length = 986
Score = 51.2 bits (121), Expect = 3e-06
Identities = 63/288 (21%), Positives = 135/288 (46%), Gaps = 43/288 (14%)
Query: 154 SPLKPVSCPKSKASDKRSLLPHQIS-------QIYDELFQIHLKLQCETAAQQKFAEELQ 206
S L P CP ++ R L ++ + ++ +++F+ LK Q E A Q AEE +
Sbjct: 630 SSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLK-QKELAHMQALAEEWK 688
Query: 207 KRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNK-ET 265
KR+R ERE L+ + + ++G ++ L + +EQ A VE +E+ +EK + ++
Sbjct: 689 KRDR---ERESLVKKKVAEYTILEGKLQKTLIDLE-KREQQLASVE--SELQREKKELQS 742
Query: 266 KRLRSSFDALKELNDTLKKQ----LNEASEENRKI---DIQAKRVQARLDNLQRKYEFM- 317
+R R+ L+EL D++++ +++ E KI + R+Q +L++ + KY+ +
Sbjct: 743 ERQRN----LQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILE 798
Query: 318 -TIQRLKGSSHAVHEMK---------------SLKQEKAPVSKTYKVPLNGQVYELLTVF 361
Q+ K + E++ K E A SK + G+ + L
Sbjct: 799 KEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARL 858
Query: 362 MDWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTE 409
+ ++++K ++ ++ + + A +++ ++ + +LL + E
Sbjct: 859 KQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNE 906
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 50.8 bits (120), Expect = 4e-06
Identities = 63/292 (21%), Positives = 120/292 (41%), Gaps = 49/292 (16%)
Query: 94 LDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEI--EKVALPTNTTSSRPRTECCSDA 151
L HD KQ+ EE + D + ++ +Q +E+ E AL TSS + D
Sbjct: 1352 LQQEHD--KQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDK 1409
Query: 152 GDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERF 211
D + C K + K Q+ + Q++ A Q+ ++ + + +
Sbjct: 1410 LDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNY 1469
Query: 212 LLEREQL------LFRHENALSKIKGV----------------EEEVLTRFQI------- 242
LE E L L R + +++ V +E+ L R QI
Sbjct: 1470 QLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDH 1529
Query: 243 IKEQHDAEVEHLTEVLK---EKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQ 299
+KEQ + E L + +K E N + +RL + E + LK+++ E + +N + +
Sbjct: 1530 LKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLM 1589
Query: 300 AKRVQARLDNL-------QRKYEFMTIQ------RLKGSSHAVHEMKSLKQE 338
+R+QA +N+ Q++ E + IQ +L+ ++ +H+ +Q+
Sbjct: 1590 MQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQD 1641
Score = 35.4 bits (80), Expect = 0.17
Identities = 34/187 (18%), Positives = 79/187 (42%), Gaps = 3/187 (1%)
Query: 156 LKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLE- 214
L + K+ + +K LL ++ + + L + L+L+ + A++ ++++L++ R L +
Sbjct: 1389 LNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQT 1448
Query: 215 --REQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSF 272
+ + + + L KIK + L K + EV+ +T K + L S
Sbjct: 1449 TGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQI 1508
Query: 273 DALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEM 332
+ ++ + + Q+ + ++ K + Q + K IQRL +E
Sbjct: 1509 HSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNEC 1568
Query: 333 KSLKQEK 339
+ ++K
Sbjct: 1569 AEMLKQK 1575
Score = 29.6 bits (65), Expect = 9.3
Identities = 50/258 (19%), Positives = 106/258 (41%), Gaps = 27/258 (10%)
Query: 99 DLKKQET--EEEL------IENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECC-- 148
+LKKQ++ EEEL EN+ R + S ++K+ + R E
Sbjct: 1149 ELKKQKSRVEEELPKVREAAENELRKQQRNVEDIS---LQKIRAESEAKQYRRELETIVR 1205
Query: 149 -SDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQK 207
+A + L+ V +A KR+ + + L +L+ T ++ + L++
Sbjct: 1206 EKEAAERELERVRQLTIEAEAKRAA-------VEENLLNFRNQLEENTFTRRTLEDHLKR 1258
Query: 208 RERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNK---E 264
++ L + EQ + L + + EEE+L + +++ + + + LKEK K E
Sbjct: 1259 KDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELE 1318
Query: 265 TKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKG 324
+R + N + +A+ +Q + + + + L+++ + +T K
Sbjct: 1319 ARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKA 1378
Query: 325 SS---HAVHEMKSLKQEK 339
+E+ +L+ EK
Sbjct: 1379 EQDMRELTYELNALQLEK 1396
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 50.8 bits (120), Expect = 4e-06
Identities = 40/183 (21%), Positives = 91/183 (49%), Gaps = 17/183 (9%)
Query: 157 KPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLERE 216
K ++ K + L HQ ++ E Q+ LK Q +T +K E+ ++ + LL+ +
Sbjct: 603 KEITVMVEKHKTELESLKHQQDALWTEKLQV-LKQQYQTE-MEKLREKCEQEKETLLKDK 660
Query: 217 QLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALK 276
+++F+ + I+ + E+ L + + + + ++ L+EVLK ++K L LK
Sbjct: 661 EIIFQ-----AHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHK----LEEELSVLK 711
Query: 277 ELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLK 336
+ D +K++L K+D Q Q ++D++ +++E + K +++++ L
Sbjct: 712 DQTDKMKQEL------EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLL 765
Query: 337 QEK 339
+E+
Sbjct: 766 KER 768
Score = 39.7 bits (91), Expect = 0.009
Identities = 65/341 (19%), Positives = 132/341 (38%), Gaps = 31/341 (9%)
Query: 69 DESKHCRTPLGSLFKHV--------NVNCLDDELDSFHDLKKQETEE--ELIEN--DYRV 116
+E K + + SL K + N L ++ + L+KQ EE EL++ D
Sbjct: 1360 EELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSF 1419
Query: 117 STSKITKQSFKEIEKVALPTNTTSS-RPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPH 175
++K+ +E+V +N S + + + + +K + S +
Sbjct: 1420 KVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDE 1479
Query: 176 QISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFL-----LEREQLLFRHENALSKIK 230
QI+ + +EL Q + + C + +++K+E L + +++ ++ K
Sbjct: 1480 QINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTI 1539
Query: 231 GVEE--EVLTRFQIIKEQHDAEV----EHLTEVLKEKNKETKRLRSSFDALKELNDTLKK 284
+E EVL + K+ E+ +H E+ +EK+ K L+ ++K
Sbjct: 1540 EIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKA 1599
Query: 285 QLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRL-----KGSSHAVHEMKSLKQEK 339
+L +E +++ K + L L+ + E + +L K K L +
Sbjct: 1600 ELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQM 1659
Query: 340 APVSKTYKVPLNGQVYELLTVFMDWISDHHL--SKVKHEES 378
+ YK + EL T + + H+ K+K ES
Sbjct: 1660 EEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVES 1700
Score = 38.5 bits (88), Expect = 0.020
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 20/173 (11%)
Query: 163 KSKASDKRSLLPHQISQIYDELFQIH-LKLQCETAAQQKFAEELQKRERFLLEREQLLFR 221
+ + +D S+ +++Q +EL +IH ++LQ +Q+ AE QK F E+E++
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQEIHEIQLQ---EKEQEVAELKQKILLFGCEKEEM--N 1091
Query: 222 HENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDT 281
E K +GV++ D + L E LK+K+ L LK +
Sbjct: 1092 KEITWLKEEGVKQ-------------DTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEK 1138
Query: 282 LKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKS 334
L+ LN++ +EN + Q ++ + +RK +T +LK + +KS
Sbjct: 1139 LEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELT-SKLKTTDEEFQSLKS 1190
Score = 36.6 bits (83), Expect = 0.076
Identities = 74/391 (18%), Positives = 160/391 (40%), Gaps = 62/391 (15%)
Query: 59 DKVGSSL--KYSDESKHCRTPLGSLFKHVNVN------CLDDELDSFHDLKKQETEEELI 110
DK+ L K ++ H + + S+ K V+ L D+++ L K E ++ L
Sbjct: 715 DKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLK-ERDKHLK 773
Query: 111 ENDYRVSTSKIT-KQSFKEIEKVALPTNTTSS-RPRTECCSDAGDSPLKPVSCPKSKASD 168
E+ V + K+S E+++ + + S + T + A + L +
Sbjct: 774 EHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLET 833
Query: 169 KRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLER------------- 215
+R LL Q++++ + + +L Q ++L+K+ + ++
Sbjct: 834 ERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLE 893
Query: 216 ---------EQLLFRHENALSKIKGVEE---EVLTRFQIIKEQ--HDAEVEHLTEVLKEK 261
+Q+L EN + +++ ++ E+LT+ KE H E+ T K K
Sbjct: 894 DGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET---KFK 950
Query: 262 NKETKRLRSSFDALKELNDTLKKQ-LNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQ 320
N+E K++ KE+ +TLKK+ L++ ++ ++++ A + + K M
Sbjct: 951 NQE-KKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQA 1009
Query: 321 RLKGSSHAVHEMKSLKQEKA------------PVSKTYKVPLNGQVYELLTVFMDWISDH 368
G S AV +++ ++E+ V ++ LN Q EL + H
Sbjct: 1010 NSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEI-------H 1062
Query: 369 HLSKVKHEESGMDGKKPQLKFASQRNDIQEK 399
+ + E+ + K+ L F ++ ++ ++
Sbjct: 1063 EIQLQEKEQEVAELKQKILLFGCEKEEMNKE 1093
Score = 33.5 bits (75), Expect = 0.65
Identities = 35/169 (20%), Positives = 74/169 (43%), Gaps = 33/169 (19%)
Query: 166 ASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENA 225
A ++ L +I ++ +L + + Q E +K ++ ++ E+ E+E L +H +
Sbjct: 1935 AEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQ-EREEKIKQEQEDLELKHNST 1993
Query: 226 LSKI----------KGVEEEVLTRFQIIK---------EQHDAEVEHLTEVLKEKNKETK 266
L ++ K E E+ + I K E H E L + + EK+ + K
Sbjct: 1994 LKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLK 2053
Query: 267 RLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYE 315
R ++ ++ +A EE ++ + + +Q +L+ LQ+KY+
Sbjct: 2054 RTAKRYE-----------EILDAREE--EMTAKVRDLQTQLEELQKKYQ 2089
Score = 32.0 bits (71), Expect = 1.9
Identities = 50/253 (19%), Positives = 94/253 (37%), Gaps = 53/253 (20%)
Query: 92 DELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDA 151
+EL H+++ QE E+E+ E ++ K+
Sbjct: 1056 EELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMN------------------------ 1091
Query: 152 GDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERF 211
K ++ K + + + L Q+ + ++ Q ET K L+K E
Sbjct: 1092 -----KEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDET----KLKAHLEKLEVD 1142
Query: 212 LLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSS 271
L N K +E L +++ E+ +V LT LK ++E + L+SS
Sbjct: 1143 L-----------NKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSS 1191
Query: 272 FDALKELNDTLKKQLNEASEENR-KIDIQAKRVQARLDNLQRKYEFMTIQRLKGS----- 325
+ + + + + SEE ++DI K+ +A L+ + E + I K +
Sbjct: 1192 HEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLE--AKTNELINISSSKTNAILSR 1249
Query: 326 -SHAVHEMKSLKQ 337
SH H +K+
Sbjct: 1250 ISHCQHRTTKVKE 1262
Score = 32.0 bits (71), Expect = 1.9
Identities = 40/178 (22%), Positives = 82/178 (46%), Gaps = 35/178 (19%)
Query: 198 QQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQ--IIKEQH-------- 247
Q+ + E++ +R L E+E+LL R + E+ ++Q +IK +H
Sbjct: 1731 QKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED 1790
Query: 248 DAEVEHLTEVLKEKNK----------ETKRLRSSFDA---LKELNDTLKKQLNE------ 288
+ + HL E L+EKNK E + +++ A L+ + D ++K L E
Sbjct: 1791 QSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQ 1850
Query: 289 -ASEENRKID---IQAKRV-QARLDNLQRKYE-FMTIQRLKGSSHAVHEMKSLKQEKA 340
++ +++D ++ K V + ++ L KYE +Q++ G + ++ +EK+
Sbjct: 1851 ILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKS 1908
>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
Length = 1235
Score = 50.8 bits (120), Expect = 4e-06
Identities = 71/321 (22%), Positives = 139/321 (43%), Gaps = 39/321 (12%)
Query: 37 FYQSKYKRRTLTSPGDLDIYSGDKVGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDS 96
F Q + K+RTL D + +GD++ LK K C + +++ D
Sbjct: 289 FIQLQEKQRTLRISHDALMANGDELNMQLK-EQRLKCCSLEKQLHSMKFSERRIEELQDR 347
Query: 97 FHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPL 156
+DL+K E EL++ +Y K+ +F + + + A
Sbjct: 348 INDLEK---ERELLKENY----DKLYDSAFSAAHEEQWKLKEQQLKVQIAQLETA----- 395
Query: 157 KPVSCPKSKASDKRSLLPHQISQ--IYDELFQIHLKLQCETAAQQKFAEELQKRERFLLE 214
KS +DK +L ++ ++L Q + +LQ + Q++ +EL+KR +
Sbjct: 396 -----LKSDLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIK---- 446
Query: 215 REQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDA 274
L+ EN ++ + E +L + Q KEQ + ++ L +V E NK+ +R A
Sbjct: 447 ----LYNQENDINADELSEALLLIKAQ--KEQKNGDLSFLVKVDSEINKDLERSMRELQA 500
Query: 275 -----LKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMT---IQRLKGSS 326
++EL T + L + N+ ++ + V +++NLQ+ YE + L +
Sbjct: 501 THAETVQELEKT-RNMLIMQHKINKDYQMEVEAVTRKMENLQQDYELKVEQYVHLLDIRA 559
Query: 327 HAVHEMKSLKQEKAPVSKTYK 347
+H++++ ++ A +K YK
Sbjct: 560 ARIHKLEAQLKDIAYGTKQYK 580
>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
Length = 1315
Score = 50.8 bits (120), Expect = 4e-06
Identities = 71/321 (22%), Positives = 139/321 (43%), Gaps = 39/321 (12%)
Query: 37 FYQSKYKRRTLTSPGDLDIYSGDKVGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDS 96
F Q + K+RTL D + +GD++ LK K C + +++ D
Sbjct: 289 FIQLQEKQRTLRISHDALMANGDELNMQLK-EQRLKCCSLEKQLHSMKFSERRIEELQDR 347
Query: 97 FHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPL 156
+DL+K E EL++ +Y K+ +F + + + A
Sbjct: 348 INDLEK---ERELLKENY----DKLYDSAFSAAHEEQWKLKEQQLKVQIAQLETA----- 395
Query: 157 KPVSCPKSKASDKRSLLPHQISQ--IYDELFQIHLKLQCETAAQQKFAEELQKRERFLLE 214
KS +DK +L ++ ++L Q + +LQ + Q++ +EL+KR +
Sbjct: 396 -----LKSDLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIK---- 446
Query: 215 REQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDA 274
L+ EN ++ + E +L + Q KEQ + ++ L +V E NK+ +R A
Sbjct: 447 ----LYNQENDINADELSEALLLIKAQ--KEQKNGDLSFLVKVDSEINKDLERSMRELQA 500
Query: 275 -----LKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMT---IQRLKGSS 326
++EL T + L + N+ ++ + V +++NLQ+ YE + L +
Sbjct: 501 THAETVQELEKT-RNMLIMQHKINKDYQMEVEAVTRKMENLQQDYELKVEQYVHLLDIRA 559
Query: 327 HAVHEMKSLKQEKAPVSKTYK 347
+H++++ ++ A +K YK
Sbjct: 560 ARIHKLEAQLKDIAYGTKQYK 580
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 50.8 bits (120), Expect = 4e-06
Identities = 53/235 (22%), Positives = 107/235 (45%), Gaps = 15/235 (6%)
Query: 88 NCLDDELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVA---LPTNTTSSRPR 144
+CLD+ F ++TE L +N + + ++E L + TSS R
Sbjct: 1112 SCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQR 1171
Query: 145 TECCSDAGDSPLKPVSCPKSKASDKRSL--LPHQISQIYDELFQIHLKLQCETAAQQKFA 202
E + ++ ++ S ++ + L +QISQ+ ++L L C+ A+++K
Sbjct: 1172 QEVKIEESEASVEGFSELENSEETRTESWELKNQISQLQEQLMM--LCADCDRASEKK-- 1227
Query: 203 EELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQ---HDAEVEHLTEVLK 259
++L L ++ ++L R A K K + E+V ++E+ + + E K
Sbjct: 1228 QDLLFDVSVLKKKLKMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNK 1287
Query: 260 EKNKETKRLRSSFDALKELNDT---LKKQLNEASEENRKIDIQAKRVQARLDNLQ 311
E E RL+ ++E+ +T L+K +E EN ++++ R+Q +++ LQ
Sbjct: 1288 ELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQ 1342
Score = 37.0 bits (84), Expect = 0.059
Identities = 64/317 (20%), Positives = 124/317 (39%), Gaps = 32/317 (10%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVS 160
K QE ++ EN+ +I+ EI ++ C + V
Sbjct: 655 KAQENMKQRHENETHTLEKQISDLK-NEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVK 713
Query: 161 CPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLF 220
+ K + L ++ L Q + E Q A +K E EQ
Sbjct: 714 LEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQF-- 771
Query: 221 RHENALSKIKGVEEEVLTRFQIIKE---QHDAEVEHLTEVLK-EKNKETKRLRSSFD--- 273
H+ L+ + VE+ L + ++ KE +H E++ E ++ E N+ T ++ + F
Sbjct: 772 -HQEQLTSL--VEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDC 828
Query: 274 ---------ALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKG 324
AL+ L +++L + E+ R+ ++ Q + + E Q L
Sbjct: 829 QKVTERCESALQSLEGRYRQELKDLQEQQRE-----EKSQWEFEKDELTQECAEAQELLK 883
Query: 325 SSHAVHEMKSL--KQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDG 382
+ + SL QE+ + KTYK LN V E + D ++S+ ++S +
Sbjct: 884 ETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSET--QQSLLSD 941
Query: 383 KKPQLKFASQRNDIQEK 399
+ +LK +S + +++E+
Sbjct: 942 QILELK-SSHKRELRER 957
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/100 (26%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Query: 249 AEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNE-------ASEEN-RKIDIQA 300
AE+ HL E + + +E ++LRS D ++L + ++++ +E N RK+D +
Sbjct: 373 AEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEY 432
Query: 301 K-RVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEK 339
K R+ A + L+++ E + Q K E++ K E+
Sbjct: 433 KERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE 472
Score = 32.3 bits (72), Expect = 1.4
Identities = 57/255 (22%), Positives = 101/255 (39%), Gaps = 44/255 (17%)
Query: 80 SLFKHVNVNCLDDELDSFHD-----------LKKQETEEELIENDYRVSTSKITKQSFKE 128
S + V L EL+ FH L+K+E +EL+E K ++ +
Sbjct: 754 SAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLE--------KHQRELQEG 805
Query: 129 IEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIH 188
EK+ N +S+ + SD + S +S R L Q +E Q
Sbjct: 806 REKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWE 865
Query: 189 L---KLQCETAAQQKFAEELQKRER-----FLLEREQLLFRHENALSKIKGVEEEVLTRF 240
+L E A Q+ +E KRE+ ERE L ++ L+ + V+ R
Sbjct: 866 FEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSM------VVERQ 919
Query: 241 QIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQA 300
Q++++ D L+ ++ + L S D + EL + K++L E E +
Sbjct: 920 QLLQDLED---------LRNVSETQQSLLS--DQILELKSSHKRELREREEVLCQAGASE 968
Query: 301 KRVQARLDNLQRKYE 315
+ RL+ L+ +++
Sbjct: 969 QLASQRLERLEMEHD 983
Score = 30.0 bits (66), Expect = 7.2
Identities = 41/207 (19%), Positives = 86/207 (41%), Gaps = 23/207 (11%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSS---RPRTECCSDAGDSPLK 157
K + +E+L E + R++ K+ KE AL + E C + +
Sbjct: 1605 KNSQNQEKLQELNQRLTEMLCQKE--KEPGNSALEEREQEKFNLKEELERCKVQSSTLVS 1662
Query: 158 PVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAA--QQKFAEELQKRERFLLER 215
+ S+ + ++ + + DEL ++ +C + QQK + L E+ L E+
Sbjct: 1663 SLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEK 1722
Query: 216 EQL---LFRHENALSKIKGVEEEVLTRFQIIKE-QHDA------------EVEHLTEVLK 259
E L L + L+K +E + T Q K +H + +V++L + ++
Sbjct: 1723 EALSEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQ 1782
Query: 260 EKNKETKRLRSSFDALKELNDTLKKQL 286
N + R++S ++ + LK+++
Sbjct: 1783 NVNLQMSRMKSDLRVTQQEKEALKQEV 1809
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 50.8 bits (120), Expect = 4e-06
Identities = 53/235 (22%), Positives = 107/235 (45%), Gaps = 15/235 (6%)
Query: 88 NCLDDELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVA---LPTNTTSSRPR 144
+CLD+ F ++TE L +N + + ++E L + TSS R
Sbjct: 1106 SCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQR 1165
Query: 145 TECCSDAGDSPLKPVSCPKSKASDKRSL--LPHQISQIYDELFQIHLKLQCETAAQQKFA 202
E + ++ ++ S ++ + L +QISQ+ ++L L C+ A+++K
Sbjct: 1166 QEVKIEESEASVEGFSELENSEETRTESWELKNQISQLQEQLMM--LCADCDRASEKK-- 1221
Query: 203 EELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQ---HDAEVEHLTEVLK 259
++L L ++ ++L R A K K + E+V ++E+ + + E K
Sbjct: 1222 QDLLFDVSVLKKKLKMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNK 1281
Query: 260 EKNKETKRLRSSFDALKELNDT---LKKQLNEASEENRKIDIQAKRVQARLDNLQ 311
E E RL+ ++E+ +T L+K +E EN ++++ R+Q +++ LQ
Sbjct: 1282 ELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQ 1336
Score = 37.0 bits (84), Expect = 0.059
Identities = 64/317 (20%), Positives = 124/317 (39%), Gaps = 32/317 (10%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVS 160
K QE ++ EN+ +I+ EI ++ C + V
Sbjct: 649 KAQENMKQRHENETHTLEKQISDLK-NEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVK 707
Query: 161 CPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLF 220
+ K + L ++ L Q + E Q A +K E EQ
Sbjct: 708 LEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQF-- 765
Query: 221 RHENALSKIKGVEEEVLTRFQIIKE---QHDAEVEHLTEVLK-EKNKETKRLRSSFD--- 273
H+ L+ + VE+ L + ++ KE +H E++ E ++ E N+ T ++ + F
Sbjct: 766 -HQEQLTSL--VEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDC 822
Query: 274 ---------ALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKG 324
AL+ L +++L + E+ R+ ++ Q + + E Q L
Sbjct: 823 QKVTERCESALQSLEGRYRQELKDLQEQQRE-----EKSQWEFEKDELTQECAEAQELLK 877
Query: 325 SSHAVHEMKSL--KQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDG 382
+ + SL QE+ + KTYK LN V E + D ++S+ ++S +
Sbjct: 878 ETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSET--QQSLLSD 935
Query: 383 KKPQLKFASQRNDIQEK 399
+ +LK +S + +++E+
Sbjct: 936 QILELK-SSHKRELRER 951
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/100 (26%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Query: 249 AEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNE-------ASEEN-RKIDIQA 300
AE+ HL E + + +E ++LRS D ++L + ++++ +E N RK+D +
Sbjct: 367 AEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEY 426
Query: 301 K-RVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEK 339
K R+ A + L+++ E + Q K E++ K E+
Sbjct: 427 KERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE 466
Score = 32.3 bits (72), Expect = 1.4
Identities = 57/255 (22%), Positives = 101/255 (39%), Gaps = 44/255 (17%)
Query: 80 SLFKHVNVNCLDDELDSFHD-----------LKKQETEEELIENDYRVSTSKITKQSFKE 128
S + V L EL+ FH L+K+E +EL+E K ++ +
Sbjct: 748 SAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLE--------KHQRELQEG 799
Query: 129 IEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIH 188
EK+ N +S+ + SD + S +S R L Q +E Q
Sbjct: 800 REKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWE 859
Query: 189 L---KLQCETAAQQKFAEELQKRER-----FLLEREQLLFRHENALSKIKGVEEEVLTRF 240
+L E A Q+ +E KRE+ ERE L ++ L+ + V+ R
Sbjct: 860 FEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSM------VVERQ 913
Query: 241 QIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQA 300
Q++++ D L+ ++ + L S D + EL + K++L E E +
Sbjct: 914 QLLQDLED---------LRNVSETQQSLLS--DQILELKSSHKRELREREEVLCQAGASE 962
Query: 301 KRVQARLDNLQRKYE 315
+ RL+ L+ +++
Sbjct: 963 QLASQRLERLEMEHD 977
Score = 30.0 bits (66), Expect = 7.2
Identities = 41/207 (19%), Positives = 86/207 (41%), Gaps = 23/207 (11%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSS---RPRTECCSDAGDSPLK 157
K + +E+L E + R++ K+ KE AL + E C + +
Sbjct: 1599 KNSQNQEKLQELNQRLTEMLCQKE--KEPGNSALEEREQEKFNLKEELERCKVQSSTLVS 1656
Query: 158 PVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAA--QQKFAEELQKRERFLLER 215
+ S+ + ++ + + DEL ++ +C + QQK + L E+ L E+
Sbjct: 1657 SLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEK 1716
Query: 216 EQL---LFRHENALSKIKGVEEEVLTRFQIIKE-QHDA------------EVEHLTEVLK 259
E L L + L+K +E + T Q K +H + +V++L + ++
Sbjct: 1717 EALSEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQ 1776
Query: 260 EKNKETKRLRSSFDALKELNDTLKKQL 286
N + R++S ++ + LK+++
Sbjct: 1777 NVNLQMSRMKSDLRVTQQEKEALKQEV 1803
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 50.8 bits (120), Expect = 4e-06
Identities = 53/235 (22%), Positives = 107/235 (45%), Gaps = 15/235 (6%)
Query: 88 NCLDDELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVA---LPTNTTSSRPR 144
+CLD+ F ++TE L +N + + ++E L + TSS R
Sbjct: 1106 SCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQR 1165
Query: 145 TECCSDAGDSPLKPVSCPKSKASDKRSL--LPHQISQIYDELFQIHLKLQCETAAQQKFA 202
E + ++ ++ S ++ + L +QISQ+ ++L L C+ A+++K
Sbjct: 1166 QEVKIEESEASVEGFSELENSEETRTESWELKNQISQLQEQLMM--LCADCDRASEKK-- 1221
Query: 203 EELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQ---HDAEVEHLTEVLK 259
++L L ++ ++L R A K K + E+V ++E+ + + E K
Sbjct: 1222 QDLLFDVSVLKKKLKMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNK 1281
Query: 260 EKNKETKRLRSSFDALKELNDT---LKKQLNEASEENRKIDIQAKRVQARLDNLQ 311
E E RL+ ++E+ +T L+K +E EN ++++ R+Q +++ LQ
Sbjct: 1282 ELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQ 1336
Score = 37.0 bits (84), Expect = 0.059
Identities = 64/317 (20%), Positives = 124/317 (39%), Gaps = 32/317 (10%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVS 160
K QE ++ EN+ +I+ EI ++ C + V
Sbjct: 649 KAQENMKQRHENETHTLEKQISDLK-NEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVK 707
Query: 161 CPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLF 220
+ K + L ++ L Q + E Q A +K E EQ
Sbjct: 708 LEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQF-- 765
Query: 221 RHENALSKIKGVEEEVLTRFQIIKE---QHDAEVEHLTEVLK-EKNKETKRLRSSFD--- 273
H+ L+ + VE+ L + ++ KE +H E++ E ++ E N+ T ++ + F
Sbjct: 766 -HQEQLTSL--VEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDC 822
Query: 274 ---------ALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKG 324
AL+ L +++L + E+ R+ ++ Q + + E Q L
Sbjct: 823 QKVTERCESALQSLEGRYRQELKDLQEQQRE-----EKSQWEFEKDELTQECAEAQELLK 877
Query: 325 SSHAVHEMKSL--KQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDG 382
+ + SL QE+ + KTYK LN V E + D ++S+ ++S +
Sbjct: 878 ETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSET--QQSLLSD 935
Query: 383 KKPQLKFASQRNDIQEK 399
+ +LK +S + +++E+
Sbjct: 936 QILELK-SSHKRELRER 951
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/100 (26%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Query: 249 AEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNE-------ASEEN-RKIDIQA 300
AE+ HL E + + +E ++LRS D ++L + ++++ +E N RK+D +
Sbjct: 367 AEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEY 426
Query: 301 K-RVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEK 339
K R+ A + L+++ E + Q K E++ K E+
Sbjct: 427 KERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE 466
Score = 32.3 bits (72), Expect = 1.4
Identities = 57/255 (22%), Positives = 101/255 (39%), Gaps = 44/255 (17%)
Query: 80 SLFKHVNVNCLDDELDSFHD-----------LKKQETEEELIENDYRVSTSKITKQSFKE 128
S + V L EL+ FH L+K+E +EL+E K ++ +
Sbjct: 748 SAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLE--------KHQRELQEG 799
Query: 129 IEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIH 188
EK+ N +S+ + SD + S +S R L Q +E Q
Sbjct: 800 REKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWE 859
Query: 189 L---KLQCETAAQQKFAEELQKRER-----FLLEREQLLFRHENALSKIKGVEEEVLTRF 240
+L E A Q+ +E KRE+ ERE L ++ L+ + V+ R
Sbjct: 860 FEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSM------VVERQ 913
Query: 241 QIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQA 300
Q++++ D L+ ++ + L S D + EL + K++L E E +
Sbjct: 914 QLLQDLED---------LRNVSETQQSLLS--DQILELKSSHKRELREREEVLCQAGASE 962
Query: 301 KRVQARLDNLQRKYE 315
+ RL+ L+ +++
Sbjct: 963 QLASQRLERLEMEHD 977
Score = 30.0 bits (66), Expect = 7.2
Identities = 41/207 (19%), Positives = 86/207 (41%), Gaps = 23/207 (11%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSS---RPRTECCSDAGDSPLK 157
K + +E+L E + R++ K+ KE AL + E C + +
Sbjct: 1599 KNSQNQEKLQELNQRLTEMLCQKE--KEPGNSALEEREQEKFNLKEELERCKVQSSTLVS 1656
Query: 158 PVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAA--QQKFAEELQKRERFLLER 215
+ S+ + ++ + + DEL ++ +C + QQK + L E+ L E+
Sbjct: 1657 SLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEK 1716
Query: 216 EQL---LFRHENALSKIKGVEEEVLTRFQIIKE-QHDA------------EVEHLTEVLK 259
E L L + L+K +E + T Q K +H + +V++L + ++
Sbjct: 1717 EALSEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQ 1776
Query: 260 EKNKETKRLRSSFDALKELNDTLKKQL 286
N + R++S ++ + LK+++
Sbjct: 1777 NVNLQMSRMKSDLRVTQQEKEALKQEV 1803
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 50.8 bits (120), Expect = 4e-06
Identities = 53/235 (22%), Positives = 107/235 (45%), Gaps = 15/235 (6%)
Query: 88 NCLDDELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVA---LPTNTTSSRPR 144
+CLD+ F ++TE L +N + + ++E L + TSS R
Sbjct: 1106 SCLDEPATEFFGNTAEQTEPFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQR 1165
Query: 145 TECCSDAGDSPLKPVSCPKSKASDKRSL--LPHQISQIYDELFQIHLKLQCETAAQQKFA 202
E + ++ ++ S ++ + L +QISQ+ ++L L C+ A+++K
Sbjct: 1166 QEVKIEESEASVEGFSELENSEETRTESWELKNQISQLQEQLMM--LCADCDRASEKK-- 1221
Query: 203 EELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQ---HDAEVEHLTEVLK 259
++L L ++ ++L R A K K + E+V ++E+ + + E K
Sbjct: 1222 QDLLFDVSVLKKKLKMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNK 1281
Query: 260 EKNKETKRLRSSFDALKELNDT---LKKQLNEASEENRKIDIQAKRVQARLDNLQ 311
E E RL+ ++E+ +T L+K +E EN ++++ R+Q +++ LQ
Sbjct: 1282 ELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQ 1336
Score = 37.0 bits (84), Expect = 0.059
Identities = 64/317 (20%), Positives = 124/317 (39%), Gaps = 32/317 (10%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVS 160
K QE ++ EN+ +I+ EI ++ C + V
Sbjct: 649 KAQENMKQRHENETHTLEKQISDLK-NEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVK 707
Query: 161 CPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLF 220
+ K + L ++ L Q + E Q A +K E EQ
Sbjct: 708 LEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQF-- 765
Query: 221 RHENALSKIKGVEEEVLTRFQIIKE---QHDAEVEHLTEVLK-EKNKETKRLRSSFD--- 273
H+ L+ + VE+ L + ++ KE +H E++ E ++ E N+ T ++ + F
Sbjct: 766 -HQEQLTSL--VEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDC 822
Query: 274 ---------ALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKG 324
AL+ L +++L + E+ R+ ++ Q + + E Q L
Sbjct: 823 QKVTERCESALQSLEGRYRQELKDLQEQQRE-----EKSQWEFEKDELTQECAEAQELLK 877
Query: 325 SSHAVHEMKSL--KQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDG 382
+ + SL QE+ + KTYK LN V E + D ++S+ ++S +
Sbjct: 878 ETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSET--QQSLLSD 935
Query: 383 KKPQLKFASQRNDIQEK 399
+ +LK +S + +++E+
Sbjct: 936 QILELK-SSHKRELRER 951
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/100 (26%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Query: 249 AEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNE-------ASEEN-RKIDIQA 300
AE+ HL E + + +E ++LRS D ++L + ++++ +E N RK+D +
Sbjct: 367 AEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEY 426
Query: 301 K-RVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEK 339
K R+ A + L+++ E + Q K E++ K E+
Sbjct: 427 KERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE 466
Score = 32.3 bits (72), Expect = 1.4
Identities = 57/255 (22%), Positives = 101/255 (39%), Gaps = 44/255 (17%)
Query: 80 SLFKHVNVNCLDDELDSFHD-----------LKKQETEEELIENDYRVSTSKITKQSFKE 128
S + V L EL+ FH L+K+E +EL+E K ++ +
Sbjct: 748 SAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLE--------KHQRELQEG 799
Query: 129 IEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIH 188
EK+ N +S+ + SD + S +S R L Q +E Q
Sbjct: 800 REKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWE 859
Query: 189 L---KLQCETAAQQKFAEELQKRER-----FLLEREQLLFRHENALSKIKGVEEEVLTRF 240
+L E A Q+ +E KRE+ ERE L ++ L+ + V+ R
Sbjct: 860 FEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSM------VVERQ 913
Query: 241 QIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQA 300
Q++++ D L+ ++ + L S D + EL + K++L E E +
Sbjct: 914 QLLQDLED---------LRNVSETQQSLLS--DQILELKSSHKRELREREEVLCQAGASE 962
Query: 301 KRVQARLDNLQRKYE 315
+ RL+ L+ +++
Sbjct: 963 QLASQRLERLEMEHD 977
Score = 30.0 bits (66), Expect = 7.2
Identities = 41/207 (19%), Positives = 86/207 (41%), Gaps = 23/207 (11%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSS---RPRTECCSDAGDSPLK 157
K + +E+L E + R++ K+ KE AL + E C + +
Sbjct: 1599 KNSQNQEKLQELNQRLTEMLCQKE--KEPGNSALEEREQEKFNLKEELERCKVQSSTLVS 1656
Query: 158 PVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAA--QQKFAEELQKRERFLLER 215
+ S+ + ++ + + DEL ++ +C + QQK + L E+ L E+
Sbjct: 1657 SLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEK 1716
Query: 216 EQL---LFRHENALSKIKGVEEEVLTRFQIIKE-QHDA------------EVEHLTEVLK 259
E L L + L+K +E + T Q K +H + +V++L + ++
Sbjct: 1717 EALSEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQ 1776
Query: 260 EKNKETKRLRSSFDALKELNDTLKKQL 286
N + R++S ++ + LK+++
Sbjct: 1777 NVNLQMSRMKSDLRVTQQEKEALKQEV 1803
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 50.4 bits (119), Expect = 5e-06
Identities = 58/287 (20%), Positives = 139/287 (48%), Gaps = 35/287 (12%)
Query: 95 DSFHDLKKQ--ETEEELIENDYRVSTSKITKQSFK-EIEKVALPTNTTSSRPRTECCSDA 151
D++ DL +Q +T EEL N+ + +I ++ + +++ AL +S + +
Sbjct: 169 DAYVDLDRQLKKTTEEL--NEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMER 226
Query: 152 GDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHL-----KLQCETAAQQKFAEELQ 206
+ + P S A + L Q+ Q+ +E F++ +++CE +K EL+
Sbjct: 227 LNQS-DSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEEL--EKEISELR 283
Query: 207 KRERFL---------LEREQLLFRHEN-ALSKIKGVEE----------EVLTRFQIIKEQ 246
++ L L+ E + RH + +SK++G E ++ + ++++E+
Sbjct: 284 QQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEK 343
Query: 247 HDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQAR 306
+ +++ T L+E+ ++ RS + K L+ +L+E S++ K+D + KR++ +
Sbjct: 344 NTMYMQN-TVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEK 402
Query: 307 LDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQ 353
+D+LQ++ + + +R + E++ ++ ++ ++ +PL Q
Sbjct: 403 VDSLQKEKDRLRTER-DSLKETIEELRCVQAQEGQLTTQGLMPLGSQ 448
Score = 39.3 bits (90), Expect = 0.012
Identities = 36/173 (20%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Query: 154 SPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLL 213
S L + K++ + L+ ++ ++ ++ ++ LQ Q AE+ ++ L
Sbjct: 494 SLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQ----DQGSKAEDSVLLKKKLE 549
Query: 214 EREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFD 273
E + L N L K + + E++ RF ++E L E L++K +E K++ +
Sbjct: 550 EHLEKLHEANNELQKKRAIIEDLEPRF----NNSSLKIEELQEALRKKEEEMKQMEERYK 605
Query: 274 ALKELNDTLKKQLNEASEENRKIDIQAKRVQAR-----LDNLQRKYEFMTIQR 321
E ++ + L+ + +IQA + Q + +L+++YE QR
Sbjct: 606 KYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQERDRLFHSLEKEYEKTKSQR 658
Score = 30.4 bits (67), Expect = 5.5
Identities = 40/192 (20%), Positives = 81/192 (42%), Gaps = 20/192 (10%)
Query: 163 KSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEEL---QKRERFLLEREQLL 219
+SK +DK ++ + D L + +L+ E + ++ EEL Q +E L + +
Sbjct: 385 ESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMP 444
Query: 220 FRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELN 279
+ + + R ++I+ QH+ ++ L + + K L+ L
Sbjct: 445 LGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEK--------IALLQSLL 496
Query: 280 DTLKKQLNEASEENRKIDIQAKRVQARLDNLQR-------KYEFMTIQRLKGSSH--AVH 330
D + NE ENR ++ + VQ++++ LQ+ K E + + K H +H
Sbjct: 497 DDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLH 556
Query: 331 EMKSLKQEKAPV 342
E + Q+K +
Sbjct: 557 EANNELQKKRAI 568
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/175 (21%), Positives = 84/175 (48%), Gaps = 25/175 (14%)
Query: 194 ETAAQQKFAEELQKRERFLLEREQ----LLFRHENALSKIKGV--EEEVLTRFQIIKEQ- 246
E + + A+E KR++ +++ E+ R +N ++ K E+E R+Q +K++
Sbjct: 157 EISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEV 216
Query: 247 --------------HDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEE 292
++ E+E L + L KNKE ++ + D +++ KK+L + E
Sbjct: 217 VRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMRE 276
Query: 293 NRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYK 347
++I+ + K + L+ + +Y I+ + +SH + ++++ K+ K YK
Sbjct: 277 QQQIEKEIKEKDSELNQKRPQY----IKAKENTSHKIKKLEAAKKSLQNAQKHYK 327
Score = 34.3 bits (77), Expect = 0.38
Identities = 55/252 (21%), Positives = 97/252 (38%), Gaps = 33/252 (13%)
Query: 98 HDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTT----SSRPRTECCSDAGD 153
H +KK E ++ ++N + K K E+EK L R E S D
Sbjct: 307 HKIKKLEAAKKSLQNAQK--HYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRD 364
Query: 154 SPL-----KPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKR 208
L K K +AS + + L ++ + + + A Q + E +K+
Sbjct: 365 LTLEENQVKKYHRLKEEASKRAATLAQELEKFNRD----------QKADQDRLDLEERKK 414
Query: 209 ERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRL 268
+ +Q L E +I+ +EE + T Q ++EQ E E LTE ++ + +
Sbjct: 415 VETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGE-LTEEVEMAKRRIDEI 473
Query: 269 RSSFDALKELNDTLKKQLNEASEENRKIDIQAK-------RVQARLDNL----QRKYEFM 317
+ + E + E+S + RK +I V RL +L Q+KY+
Sbjct: 474 NKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIA 533
Query: 318 TIQRLKGSSHAV 329
+ L + A+
Sbjct: 534 VTKVLGKNMDAI 545
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 48.1 bits (113), Expect = 3e-05
Identities = 54/233 (23%), Positives = 100/233 (42%), Gaps = 28/233 (12%)
Query: 88 NCLDDELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTEC 147
N +D + D K+ E + +E + + K+ K + E+EK + +E
Sbjct: 17 NAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKL-KGTEDEVEKYS----------ESEK 65
Query: 148 CSDAGDSPLKPVSCPKSKASDKRSLLPHQISQI----------YDELFQIHLKLQCETAA 197
+D + +K + K +K L Q+ + Y+E+ + + L+ E
Sbjct: 66 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
Query: 198 QQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEV 257
++ AE + R R L E+ L + AL + EEE T+ +++++ E++ L E
Sbjct: 126 SEERAEVAESRARQL---EEELRTMDQALKSLMASEEEYSTK----EDKYEEEIKLLEEK 178
Query: 258 LKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNL 310
LKE + S L++ D L++ L A EEN +I + L+NL
Sbjct: 179 LKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 48.1 bits (113), Expect = 3e-05
Identities = 61/263 (23%), Positives = 113/263 (42%), Gaps = 34/263 (12%)
Query: 163 KSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFL---------- 212
K ++ + L H I D+L Q L+CE + ++ Q+++ F+
Sbjct: 1349 KRQSEKEMEELHHNI----DDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTE 1404
Query: 213 LEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSF 272
LE E+ L HE+ + +I+ +E+ +L R ++E E +E+ K K +
Sbjct: 1405 LEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFT 1464
Query: 273 DALKELNDT------LKKQLNEASEENRKIDIQAKRVQARLDNLQR---KYE--FMTIQR 321
DA + L T L+++ E + K D Q + +QA +L++ K E I +
Sbjct: 1465 DAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINK 1524
Query: 322 LKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMD 381
+ + + + S K+EK + K+ + ++ E DHHL +K E +
Sbjct: 1525 IVAAKDSDFQCLSKKKEKL-TEELQKLQKDIEMAER-------NEDHHLQVLKESEVLLQ 1576
Query: 382 GKKPQL-KFASQRNDIQEKCVKL 403
K+ +L K SQ Q++ L
Sbjct: 1577 AKRAELEKLKSQVTSQQQEMAVL 1599
Score = 45.4 bits (106), Expect = 2e-04
Identities = 69/326 (21%), Positives = 127/326 (38%), Gaps = 44/326 (13%)
Query: 97 FHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPL 156
F D +K EEE + +V ++I + K +++ + R E + L
Sbjct: 1915 FEDCQK---EEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTL 1971
Query: 157 KPVSCPKSKA-SDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLER 215
K K +D++S L +S++ ++ LQ E + + L + +R L ER
Sbjct: 1972 KEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRT-LQEEERWCESLEKTLSQTKRQLSER 2030
Query: 216 EQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDAL 275
EQ L L ++ + + F +++ Q L E+ K K++ S +AL
Sbjct: 2031 EQQLVEKSGELLALQKEADSMRADFSLLRNQF----------LTERKKAEKQVASLKEAL 2080
Query: 276 KELNDTLKKQLNEASEENRKIDIQ--------------AKRVQARLDNLQRKYEFMTIQR 321
K L+K L E +EN I + A+R+ L+ +Q YE+ +++
Sbjct: 2081 KIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQ--YEYTELKK 2138
Query: 322 LKGSSHAVHE--------MKSLKQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKV 373
+ + M++LK E +T LN + EL + L +
Sbjct: 2139 QMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADL-----EAILERN 2193
Query: 374 KHEESGMDGKKPQLKFASQRNDIQEK 399
++ E ++ K L F +EK
Sbjct: 2194 ENLEGELESLKENLPFTMNEGPFEEK 2219
Score = 40.8 bits (94), Expect = 0.004
Identities = 49/241 (20%), Positives = 102/241 (42%), Gaps = 19/241 (7%)
Query: 93 ELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTEC--CSD 150
E + DL++Q TE ++ N+ + K + +++ +++ + EC D
Sbjct: 588 ETEEIKDLEEQLTEGQIAANE---ALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRD 644
Query: 151 AGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRER 210
++ L+ ++ + D+ ++ + EL ++ LQ + +
Sbjct: 645 EKETLLQRLT-EVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSA 703
Query: 211 FLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLK----------E 260
+ E E L + +++K E+V Q+ + AE+E + LK E
Sbjct: 704 YEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEE 763
Query: 261 KNKETKRLRSSFDALKELNDTLKKQLNEASEE-NRKID--IQAKRVQARLDNLQRKYEFM 317
K +E L + L++ N+ LK+QL + N +D ++ + V AR+D L+RK +
Sbjct: 764 KEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLG 823
Query: 318 T 318
T
Sbjct: 824 T 824
Score = 39.7 bits (91), Expect = 0.009
Identities = 80/341 (23%), Positives = 139/341 (40%), Gaps = 61/341 (17%)
Query: 91 DDELDSFHDLKKQ--ETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECC 148
+D +D ++K + EL E D ++ ++ KE K A+ T + R +
Sbjct: 1415 EDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTE 1474
Query: 149 SDAGD----------SPLKPVSCPKSKASDKRSLLPHQISQ--IYDELFQI----HLKLQ 192
SDA + + +K +S +D + L H+I Q I E+ +I Q
Sbjct: 1475 SDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQ 1534
Query: 193 CETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVE 252
C + ++K EELQK ++ I+ E Q++KE +EV
Sbjct: 1535 CLSKKKEKLTEELQKLQK-----------------DIEMAERNEDHHLQVLKE---SEV- 1573
Query: 253 HLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQR 312
+L+ K E ++L+S + ++ L +QL EE +Q VQA+ D LQ
Sbjct: 1574 ----LLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHL--LQGSMVQAKAD-LQE 1626
Query: 313 KYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSK 372
+ + +H + E+KSL +E + K LN Q+ E T L+
Sbjct: 1627 ALRLGETEVTEKCNH-IREVKSLLEELS----FQKGELNVQISERKT---------QLTL 1672
Query: 373 VKHE-ESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQLQ 412
+K E E + + L+ S+ + + +L L +LQ
Sbjct: 1673 IKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQ 1713
Score = 37.0 bits (84), Expect = 0.059
Identities = 54/284 (19%), Positives = 111/284 (39%), Gaps = 58/284 (20%)
Query: 92 DELDSFHDLKKQETEEEL---------IENDYRVSTSKITKQSF---KEIEKVALPTNTT 139
+E+ DL+ QE +EE +E ++ +K +Q F KE++K+
Sbjct: 927 EEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLK------ 980
Query: 140 SSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQ 199
K V+ A+ + ++ Q+ ++ + +I+ Q
Sbjct: 981 -----------------KAVATSDKLATAELTIAKDQLKSLHGTVMKIN----------Q 1013
Query: 200 KFAEELQKRERFLLEREQL---LFRHENALSKIKGVEEEVLTRFQIIKEQHDA------- 249
+ AEELQ+ ERF + Q L R E + ++ + + +F++ E+
Sbjct: 1014 ERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEKTGVGTGANSQ 1073
Query: 250 --EVEHLTEVLKEKNKETKRLRSSFDALKELN-DTLKKQLNEASEENRKIDIQAKRVQAR 306
E+E L E ++ + E RL++ D N + L E +E R++ Q + +
Sbjct: 1074 VLEIEKLNETMERQRTEIARLQNVLDLTGSDNKGGFENVLEEIAELRREVSYQNDYISSM 1133
Query: 307 LDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPL 350
D +R+ + + S + H ++ K + + P+
Sbjct: 1134 ADPFKRRGYWYFMPPPPSSKVSSHSSQATKDSGVGLKYSASTPV 1177
Score = 33.1 bits (74), Expect = 0.85
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Query: 215 REQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKR-LRSSFD 273
+EQ L +++ +E+L+R E+ E LTE N+ K+ L
Sbjct: 560 KEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVIS 619
Query: 274 ALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSS--HAVHE 331
L+E T+K Q +A E RK+ + + + RL ++++ + + I + + + E
Sbjct: 620 GLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAE 679
Query: 332 MKSLKQEKAPVS 343
++S QE+ V+
Sbjct: 680 LESALQEQHEVN 691
Score = 31.2 bits (69), Expect = 3.2
Identities = 32/162 (19%), Positives = 73/162 (45%), Gaps = 14/162 (8%)
Query: 152 GDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERF 211
G +PL K K K S ++S+++DE+ + ++ T ++ E +Q ++
Sbjct: 431 GHTPLDTQLEDKEK---KISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKIS 487
Query: 212 LLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSS 271
++ L + L + + +E L + ++E + + K KE K L+ +
Sbjct: 488 EAGKDLLYKQLSGRLQLVNKLRQEALDL--------ELQMEKQKQEIAGKQKEIKDLQIA 539
Query: 272 FDALKELNDTLKKQLNEASEENRKIDI---QAKRVQARLDNL 310
D+L + + S + +++DI Q +++++RLD +
Sbjct: 540 IDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEI 581
Score = 30.4 bits (67), Expect = 5.5
Identities = 26/121 (21%), Positives = 56/121 (46%), Gaps = 10/121 (8%)
Query: 203 EELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTE----VL 258
+E++K E L + + +H+ L I + + Q +K QHD V L + VL
Sbjct: 1675 QEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVL 1734
Query: 259 KEK------NKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQR 312
+EK + +++ + + K+L + K+++ + E+R + + + ++LQ
Sbjct: 1735 EEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQE 1794
Query: 313 K 313
K
Sbjct: 1795 K 1795
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/224 (22%), Positives = 98/224 (43%), Gaps = 21/224 (9%)
Query: 100 LKKQETEEELIENDYRVSTSKITKQS------FKEIEKVALPTNTTSSRPRTECCSDAGD 153
L++ + ++ +E D +++T I + + +E K + + T CS +
Sbjct: 331 LQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSL--E 388
Query: 154 SPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLL 213
L+ K D+ +L ++ + EL ++ T EL++ ++ L
Sbjct: 389 ELLRTEQQRLEKNEDQLKILTMELQKKSSELEEM-------TKLTNNKEVELEELKKVLG 441
Query: 214 EREQLLFRH---ENALSKIKGVEEEVLTRFQII-KEQHDAEVEHLTEVLKEK--NKETKR 267
E+E LL+ + E ++KG E+E++ Q KE HD E++ E+ +KE K
Sbjct: 442 EKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKD 501
Query: 268 LRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQ 311
L++ + K N L N+ S EN+++ + + L N Q
Sbjct: 502 LKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQ 545
Score = 37.7 bits (86), Expect = 0.034
Identities = 39/192 (20%), Positives = 88/192 (45%), Gaps = 4/192 (2%)
Query: 173 LPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGV 232
L +++ + +EL Q +++C+ ++ L+K+ + + L + AL K
Sbjct: 572 LRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTA 631
Query: 233 EEEVLTRFQIIKEQHDAEVEHLT----EVLKEKNKETKRLRSSFDALKELNDTLKKQLNE 288
E + L ++I + + E+E E+ KE + + S + L E + K +E
Sbjct: 632 ESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADE 691
Query: 289 ASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKV 348
A + ++ID + + A + L K++ + ++ + KS +QE++ + + ++
Sbjct: 692 AVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEI 751
Query: 349 PLNGQVYELLTV 360
L+ ELL+V
Sbjct: 752 ELSNLKAELLSV 763
Score = 36.2 bits (82), Expect = 0.100
Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 183 ELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENAL-SKIKGVEEEVLTRFQ 241
EL Q + E QQ+ +K+E +L++ + L E L ++++ V EE+ +
Sbjct: 529 ELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRD 588
Query: 242 IIKEQHDAEVEH---LTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDI 298
+K + D E+ L + ++ KNK + L+ ALK+ KQLN + K+++
Sbjct: 589 EVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLEL 648
Query: 299 QAKRVQARLDNLQRKYE 315
+ + + + + Y+
Sbjct: 649 ELESAKQKFGEITDTYQ 665
Score = 32.3 bits (72), Expect = 1.4
Identities = 44/177 (24%), Positives = 80/177 (45%), Gaps = 29/177 (16%)
Query: 163 KSKASDKRSLLPHQISQIYD-ELFQIHLKLQCETAAQQKFAE-------ELQKR----ER 210
++KA K+ + +Y+ ++ ++ L+L+ +A+QKF E E++ + E
Sbjct: 621 ENKALKKKGTAESKQLNVYEIKVNKLELELE---SAKQKFGEITDTYQKEIEDKKISEEN 677
Query: 211 FLLEREQLLFRHENALSKIKGVEE-------EVLTRFQIIKEQHDAEVEHLTEVL---KE 260
L E E+ + A+ K +++ E++ + K Q+D +E L K
Sbjct: 678 LLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKS 737
Query: 261 KNKETKRLRSSFDA----LKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRK 313
K +E LR+S + LK ++KKQL EE K+ +AK A L + K
Sbjct: 738 KEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDK 794
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 47.0 bits (110), Expect = 6e-05
Identities = 61/246 (24%), Positives = 104/246 (42%), Gaps = 21/246 (8%)
Query: 66 KYSDESKHCRTPLGSLFKHVNVNCLDDELD-SFHDLKKQETEEELIENDYRVSTSKITKQ 124
KYS+ K + L K D E D + + + Q EEEL R++T+ Q
Sbjct: 59 KYSESVKEAQEKLEQAEKKAT----DAEADVASLNRRIQLVEEELDRAQERLATAL---Q 111
Query: 125 SFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDEL 184
+E EK A + D L+ + ++K + S + Y+E+
Sbjct: 112 KLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDS------DRKYEEV 165
Query: 185 FQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIK 244
+ + L+ E ++ AE + R R L E+ L + AL + EEE T+ +
Sbjct: 166 ARKLVILEGELERSEERAEVAESRARQL---EEELRTMDQALKSLMASEEEYSTK----E 218
Query: 245 EQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQ 304
++++ E++ L E LKE + S L++ D L++ L A EEN +I +
Sbjct: 219 DKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTL 278
Query: 305 ARLDNL 310
L+NL
Sbjct: 279 LELNNL 284
Score = 32.7 bits (73), Expect = 1.1
Identities = 40/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 189 LKLQCETA---AQQKFAEELQKRERFL-LEREQLLFRHENALSKIKGVEEEVLTRFQIIK 244
LKL E A A+Q A++ Q +R LE EQ + K+KG E+EV + +K
Sbjct: 11 LKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQ-----KKLKGTEDEVEKYSESVK 65
Query: 245 ------EQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDI 298
EQ + + + N+ + + D +E T ++L EA + + +
Sbjct: 66 EAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
Query: 299 QAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKA 340
K ++ R + K E +Q LK + H + +E A
Sbjct: 126 GMKVIENRAMKDEEKMELQEMQ-LKEAKHIAEDSDRKYEEVA 166
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 47.0 bits (110), Expect = 6e-05
Identities = 55/241 (22%), Positives = 102/241 (42%), Gaps = 28/241 (11%)
Query: 98 HDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLK 157
++L E E EL++ +++ KIT + + +E+ N+ R + LK
Sbjct: 632 NELHHLEKENELLQK--KITNLKITCEKIEALEQ----ENSELERENRK---------LK 676
Query: 158 PVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQ 217
+ + L + SQ+ +E ++ ++ A K A+ + + E+EQ
Sbjct: 677 KTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Query: 218 LLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKE 277
L E + K E R ++ + D E + L + L+ NK+ ++L S L+
Sbjct: 737 LKKGLELLKASFKKTE-----RLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEM 791
Query: 278 LNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQ 337
N TL+K L E + I +KR++ +L+ + E T Q K E K L+Q
Sbjct: 792 ENQTLQKNLEE-------LKISSKRLE-QLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Query: 338 E 338
+
Sbjct: 844 Q 844
Score = 42.0 bits (97), Expect = 0.002
Identities = 69/328 (21%), Positives = 139/328 (42%), Gaps = 43/328 (13%)
Query: 99 DLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKP 158
DL K++ + E R ++ + K E E L +S R R++ ++A
Sbjct: 530 DLMKEKAQLEKTIETLRENSERQIK--ILEQENEHLNQTVSSLRQRSQISAEA------- 580
Query: 159 VSCPKSKASDKRSLLPHQ-ISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQ 217
+ K +K + + H+ I + +L +I + + + + E+ ++ E LE E
Sbjct: 581 ----RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE--LENEL 634
Query: 218 LLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKE 277
EN L + K +T +I E+ +E L + E +E ++L+ + D+ K
Sbjct: 635 HHLEKENELLQKK------ITNLKITCEK----IEALEQENSELERENRKLKKTLDSFKN 684
Query: 278 LN---DTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKS 334
L ++L+K+ ++ EEN ++ +R L K + ++ + S K
Sbjct: 685 LTFQLESLEKENSQLDEEN----LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 740
Query: 335 LKQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDGKK---------- 384
L+ KA KT ++ ++ Q ++ + ++ K++ ES + +
Sbjct: 741 LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNL 800
Query: 385 PQLKFASQRNDIQEKCVKLLPLMTEQLQ 412
+LK +S+R + EK K L T QL+
Sbjct: 801 EELKISSKRLEQLEKENKSLEQETSQLE 828
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 47.0 bits (110), Expect = 6e-05
Identities = 55/241 (22%), Positives = 102/241 (42%), Gaps = 28/241 (11%)
Query: 98 HDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLK 157
++L E E EL++ +++ KIT + + +E+ N+ R + LK
Sbjct: 632 NELHHLEKENELLQK--KITNLKITCEKIEALEQ----ENSELERENRK---------LK 676
Query: 158 PVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQ 217
+ + L + SQ+ +E ++ ++ A K A+ + + E+EQ
Sbjct: 677 KTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Query: 218 LLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKE 277
L E + K E R ++ + D E + L + L+ NK+ ++L S L+
Sbjct: 737 LKKGLELLKASFKKTE-----RLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEM 791
Query: 278 LNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQ 337
N TL+K L E + I +KR++ +L+ + E T Q K E K L+Q
Sbjct: 792 ENQTLQKNLEE-------LKISSKRLE-QLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Query: 338 E 338
+
Sbjct: 844 Q 844
Score = 42.0 bits (97), Expect = 0.002
Identities = 69/328 (21%), Positives = 139/328 (42%), Gaps = 43/328 (13%)
Query: 99 DLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKP 158
DL K++ + E R ++ + K E E L +S R R++ ++A
Sbjct: 530 DLMKEKAQLEKTIETLRENSERQIK--ILEQENEHLNQTVSSLRQRSQISAEA------- 580
Query: 159 VSCPKSKASDKRSLLPHQ-ISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQ 217
+ K +K + + H+ I + +L +I + + + + E+ ++ E LE E
Sbjct: 581 ----RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE--LENEL 634
Query: 218 LLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKE 277
EN L + K +T +I E+ +E L + E +E ++L+ + D+ K
Sbjct: 635 HHLEKENELLQKK------ITNLKITCEK----IEALEQENSELERENRKLKKTLDSFKN 684
Query: 278 LN---DTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKS 334
L ++L+K+ ++ EEN ++ +R L K + ++ + S K
Sbjct: 685 LTFQLESLEKENSQLDEEN----LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 740
Query: 335 LKQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDGKK---------- 384
L+ KA KT ++ ++ Q ++ + ++ K++ ES + +
Sbjct: 741 LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNL 800
Query: 385 PQLKFASQRNDIQEKCVKLLPLMTEQLQ 412
+LK +S+R + EK K L T QL+
Sbjct: 801 EELKISSKRLEQLEKENKSLEQETSQLE 828
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 46.2 bits (108), Expect = 1e-04
Identities = 61/287 (21%), Positives = 123/287 (42%), Gaps = 51/287 (17%)
Query: 56 YSGDKVGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDSFHDLKKQETEEELIENDYR 115
Y+ D+ S+L+Y++ +K+ + +N + D L F K+ E ++ +E
Sbjct: 327 YNYDETISTLRYANRAKNIKNKA-----RINEDPKDALLRQFQ--KEIEELKKKLEEGEE 379
Query: 116 VSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPH 175
+S S I+ + E+ + G+ K + K K+ + P
Sbjct: 380 ISGSDISGSEEDDDEE-----------------GEVGEDGEK-----RKKRRGKKKVSPD 417
Query: 176 QI----SQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKG 231
++ ++I +E + KL E + K EL+KRE+ LL+ +Q H++ L K+
Sbjct: 418 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQ---EHQSLLEKLSA 474
Query: 232 VEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASE 291
+E++V+ + A+ E ++L+E N E + R + + L+++L E +
Sbjct: 475 LEKKVIVGGVDLL----AKAEEQEKLLEESNMELEERR-------KRAEQLRRELEEKEQ 523
Query: 292 ENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQE 338
E I+ + +Q +K + + + S EM L+QE
Sbjct: 524 ERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKS----EMADLQQE 566
>gi|31377634 guanylate binding protein 4 [Homo sapiens]
Length = 640
Score = 46.2 bits (108), Expect = 1e-04
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 26/212 (12%)
Query: 71 SKHCRTPLGSLFKHVNVNCLDD--ELDSFHDLKKQETEEELIENDYRVSTSKITK----- 123
+K+C+ L L +H+ + L + H+L +E ++ +E DY++ K K
Sbjct: 418 AKYCQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQ--VEWDYKLVPRKGVKANEVL 475
Query: 124 QSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDE 183
Q+F + + V + S + T AG+ + K A ++ LL + +
Sbjct: 476 QNFLQSQVVVEESILQSDKALT-----AGEKAIAAERAMKEAAEKEQELLREKQKE---- 526
Query: 184 LFQIHLKLQCETAAQQKFAEELQKRERFLLE-REQLLFRHENALS-KIKGVEEEVLTRFQ 241
+ Q A ++ F E + + E+ L E RE LL HE L K+K EE + FQ
Sbjct: 527 ------QQQMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQ 580
Query: 242 IIKEQHDAEVEHLTEVLKEKNKETKRLRSSFD 273
EQ + E+ L E ++ E RL D
Sbjct: 581 KKSEQLNKEINQLKEKIESTKNEQLRLLKILD 612
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/270 (20%), Positives = 112/270 (41%), Gaps = 29/270 (10%)
Query: 100 LKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPV 159
L KQE E+++++ D+ + S+ TK +E+ T T L+ V
Sbjct: 802 LTKQEEEKQILKQDFE-TLSQETKIQHEELNNRIQTTVTE----------------LQKV 844
Query: 160 SCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLL 219
K + S + ++S++ D L + + E + +L+K + L + QL
Sbjct: 845 KMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL--KHQLQ 902
Query: 220 FRHENALSKIKGV------EEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFD 273
+ EN L + K + E+E + ++ ++ LK+ KE ++L+ + +
Sbjct: 903 VQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNIN 962
Query: 274 ALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMK 333
LK+ ++ KKQ+ EA + KI + K L+N ++ Q L + ++
Sbjct: 963 ELKQSSEQKKKQI-EALQGELKIAVLQK---TELENKLQQQLTQAAQELAAEKEKISVLQ 1018
Query: 334 SLKQEKAPVSKTYKVPLNGQVYELLTVFMD 363
+ ++ K + G+ ELL D
Sbjct: 1019 NNYEKSQETFKQLQSDFYGRESELLATRQD 1048
Score = 42.4 bits (98), Expect = 0.001
Identities = 59/264 (22%), Positives = 116/264 (43%), Gaps = 38/264 (14%)
Query: 101 KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVS 160
++Q + E+L++ + +V+ ++ +E K + TN+T + + +
Sbjct: 440 QRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKV-TNSTELQHQLDKTKQQHQEQQALQQ 498
Query: 161 CPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLF 220
+K + ++ L + QI D+ K+Q A QK E + LLE+E+
Sbjct: 499 STTAKLREAQNDLEQVLRQIGDK----DQKIQNLEALLQKSKENIS-----LLEKER--- 546
Query: 221 RHENALSKIKGVEEEVLTRFQIIKEQH--DAEVEHLTEVLKEKNKETKR----------- 267
E+ +KI+ E E Q+ ++ H +V LTE LK +++ K+
Sbjct: 547 --EDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQE 604
Query: 268 ----LRSSFDALKELNDT---LKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQ 320
LR++ D + L + L QLNE+ E+ ++DIQ ++A+ + L T Q
Sbjct: 605 QKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQ---IKAKTELLLSAEAAKTAQ 661
Query: 321 RLKGSSHAVHEMKSLKQEKAPVSK 344
R +H +L+ ++ ++K
Sbjct: 662 RADLQNHLDTAQNALQDKQQELNK 685
Score = 35.4 bits (80), Expect = 0.17
Identities = 74/322 (22%), Positives = 133/322 (41%), Gaps = 42/322 (13%)
Query: 90 LDDELDSFHDLKKQ--ETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTS-SRPRTE 146
L+ E ++ H LK + +E+LI+ KQ+ KE +++ N S + +
Sbjct: 919 LEKEKEASHQLKLELNSMQEQLIQ------AQNTLKQNEKEEQQLQGNINELKQSSEQKK 972
Query: 147 CCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLK---LQCETAAQQKFAE 203
+A LK K++ +K L Q++Q EL K LQ Q+ +
Sbjct: 973 KQIEALQGELKIAVLQKTELENK---LQQQLTQAAQELAAEKEKISVLQNNYEKSQETFK 1029
Query: 204 ELQK----RERFLLEREQLLFRHENALSKIK----------GVEEEVLTRFQIIK---EQ 246
+LQ RE LL Q L E LS + G + +++ + K EQ
Sbjct: 1030 QLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQ 1089
Query: 247 HDAEVEH--------LTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDI 298
A+ E L ++ KEK+ + K L + L E+ + +Q E ++ N ++
Sbjct: 1090 DSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKS 1149
Query: 299 QAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELL 358
+ NL+ + + Q+L+ A +++QEK + K + + EL
Sbjct: 1150 HKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRN-QQILKDQVKKEEEELK 1208
Query: 359 TVFMDWISDHHLSKVKHEESGM 380
F++ + H S++K +E GM
Sbjct: 1209 KEFIEKEAKLH-SEIKEKEVGM 1229
Score = 34.7 bits (78), Expect = 0.29
Identities = 61/336 (18%), Positives = 143/336 (42%), Gaps = 42/336 (12%)
Query: 90 LDDELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCS 149
L EL+ + L++QE + + + D + +Q +E + T + + +
Sbjct: 109 LKKELEKYQGLQQQEAKPDGLVTDSSAELQSL-EQQLEEAQ-----TENFNIKQMKDLFE 162
Query: 150 DAGDSPLKPVSCPKSKASDKRSL---LPHQISQIYDELFQIHLKLQC--ETAAQQKFAEE 204
++ KSK ++RSL +++++ +EL + +Q Q+ E+
Sbjct: 163 QKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIED 222
Query: 205 LQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNK- 263
+ ++ L++ + L+ +N + + E++ + ++ Q+ + ++++ E K
Sbjct: 223 VAVLKKELVQVQTLM---DNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKG 279
Query: 264 ---------ETKRLRSSFDALKELNDTLKKQLNEASEENRKID-------IQAKRVQARL 307
E ++L+SS + L + N TL + L + ++ K++ + K +QA L
Sbjct: 280 PQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATL 339
Query: 308 DNLQRKYEFMTIQ-RLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELLTVFMDWIS 366
Q+ + +Q RL S ++H + EK ++ K L+ E+ T + +
Sbjct: 340 H--QKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELS----EVETKYQHLKA 393
Query: 367 DHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVK 402
+ + + EE G L+ S+ N + K ++
Sbjct: 394 EFKQLQQQREEKEQHG----LQLQSEINQLHSKLLE 425
Score = 33.9 bits (76), Expect = 0.50
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 19/151 (12%)
Query: 199 QKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVL 258
Q+ L E L L A K+K EV T++Q +K AE + L +
Sbjct: 347 QQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLK----AEFKQLQQQR 402
Query: 259 KEKNKETKRLRSSFDALK-----------ELNDTLKKQLNEASEENRKIDIQAKRVQARL 307
+EK + +L+S + L E + LK+Q +SE+ + Q +Q +L
Sbjct: 403 EEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKL 462
Query: 308 DNLQRKYEFMTIQRLKGSSHAVHEMKSLKQE 338
L+ + + +++ S+ H++ KQ+
Sbjct: 463 SRLEEQLK----EKVTNSTELQHQLDKTKQQ 489
Score = 33.1 bits (74), Expect = 0.85
Identities = 41/227 (18%), Positives = 96/227 (42%), Gaps = 18/227 (7%)
Query: 127 KEIEKVA--LPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDEL 184
+E+ K+ L T + + E CS +S LK K L QI ++ +
Sbjct: 681 QELNKITTQLDQVTAKLQDKQEHCSQL-ESHLKEYKEKYLSLEQKTEELEGQIKKLEADS 739
Query: 185 FQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIK 244
++ A++++ ++LQ++ + + E LSK +E+E+++ ++
Sbjct: 740 LEVK-------ASKEQALQDLQQQRQLNTDLEL----RATELSKQLEMEKEIVSSTRLDL 788
Query: 245 EQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASE----ENRKIDIQA 300
++ +E + + L ++ +E + L+ F+ L + ++LN + E +K+ ++
Sbjct: 789 QKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEK 848
Query: 301 KRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYK 347
+ + L ++ K ++ S E + K + KT K
Sbjct: 849 EALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCK 895
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/255 (21%), Positives = 111/255 (43%), Gaps = 28/255 (10%)
Query: 96 SFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSP 155
S H+ +++E EEE + D S+ + +S ++ A N T + D ++
Sbjct: 595 SDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENS 654
Query: 156 LKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLER 215
K + K + +K +L H+I E Q+ L + + ++EE K+ R E+
Sbjct: 655 QKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNL----GSVESYSEEKAKKVRSEYEK 710
Query: 216 EQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDAL 275
K++ + +E L R Q +++H L + + K+ K+L+ +
Sbjct: 711 ------------KLQAMNKE-LQRLQAAQKEH----ARLLKNQSQYEKQLKKLQQDVMEM 753
Query: 276 KELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRK--YEFMTIQRLKGSSHAV---- 329
K+ L KQ+ E E+ R + + R A+L QRK ++ ++ K + V
Sbjct: 754 KKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRK 813
Query: 330 -HEMKSLKQEKAPVS 343
E+ +L+++ P+S
Sbjct: 814 TEEVTALRRQVRPMS 828
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 45.1 bits (105), Expect = 2e-04
Identities = 55/228 (24%), Positives = 93/228 (40%), Gaps = 39/228 (17%)
Query: 206 QKRERFLLEREQLLFRHENALS---------KIKGVEEEVLTRFQIIKEQHDAEVEHLTE 256
QK+E L QL HE AL +I+ +E E+ TR++ + AEV+ L E
Sbjct: 705 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI-TRYKDESSKAQAEVDRLLE 763
Query: 257 VLK----EKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQR 312
+LK EKN + K++ +K+ N + ++ E +K + + R DNL
Sbjct: 764 ILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLND 823
Query: 313 KYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPL----------NGQVYELLTVFM 362
+ + L+ + E++ +E ++ ++ L QV ELL
Sbjct: 824 SSQQLQ-DSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMA-- 880
Query: 363 DWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQ 410
+ KVK E M + K +S + + EK L L E+
Sbjct: 881 -------MEKVKQELESM-----KAKLSSTQQSLAEKETHLTNLRAER 916
Score = 32.0 bits (71), Expect = 1.9
Identities = 41/185 (22%), Positives = 76/185 (41%), Gaps = 32/185 (17%)
Query: 163 KSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRH 222
K K++ + + D Q+ L+ + ++ E L++ + ERE +L +
Sbjct: 804 KKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQE 863
Query: 223 ENALSKIKGVEEEVLTRFQIIKEQHD-------------AEVE------------HLTEV 257
E+A + + EE+L + +K++ + AE E HL EV
Sbjct: 864 ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEV 923
Query: 258 LKEKNKETKRLRSSFD---ALKELNDTLKKQLNEAS----EENRKIDIQAKRVQARLDNL 310
L+ K + S D AL EL+ + KK E + E++R + ++ Q R+ +
Sbjct: 924 LEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLM 983
Query: 311 QRKYE 315
YE
Sbjct: 984 ADNYE 988
Score = 29.6 bits (65), Expect = 9.3
Identities = 35/162 (21%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 180 IYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTR 239
I+ E +++ +Q E Q + LQ R + QL + ++ + V E
Sbjct: 210 IWKEQYRV---VQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEEN 266
Query: 240 FQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKI--D 297
FQ + +H+ + KE LR + + ++ +T K+ LN E +K+
Sbjct: 267 FQRLHAEHERQA-----------KELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEM 315
Query: 298 IQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEK 339
+Q+K + A+ + + +RL + VH ++SL ++K
Sbjct: 316 LQSKGLSAK----ATEEDHERTRRLAEAEMHVHHLESLLEQK 353
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 45.1 bits (105), Expect = 2e-04
Identities = 55/228 (24%), Positives = 93/228 (40%), Gaps = 39/228 (17%)
Query: 206 QKRERFLLEREQLLFRHENALS---------KIKGVEEEVLTRFQIIKEQHDAEVEHLTE 256
QK+E L QL HE AL +I+ +E E+ TR++ + AEV+ L E
Sbjct: 677 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI-TRYKDESSKAQAEVDRLLE 735
Query: 257 VLK----EKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQR 312
+LK EKN + K++ +K+ N + ++ E +K + + R DNL
Sbjct: 736 ILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLND 795
Query: 313 KYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPL----------NGQVYELLTVFM 362
+ + L+ + E++ +E ++ ++ L QV ELL
Sbjct: 796 SSQQLQ-DSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMA-- 852
Query: 363 DWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQ 410
+ KVK E M + K +S + + EK L L E+
Sbjct: 853 -------MEKVKQELESM-----KAKLSSTQQSLAEKETHLTNLRAER 888
Score = 32.0 bits (71), Expect = 1.9
Identities = 41/185 (22%), Positives = 76/185 (41%), Gaps = 32/185 (17%)
Query: 163 KSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRH 222
K K++ + + D Q+ L+ + ++ E L++ + ERE +L +
Sbjct: 776 KKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQE 835
Query: 223 ENALSKIKGVEEEVLTRFQIIKEQHD-------------AEVE------------HLTEV 257
E+A + + EE+L + +K++ + AE E HL EV
Sbjct: 836 ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEV 895
Query: 258 LKEKNKETKRLRSSFD---ALKELNDTLKKQLNEAS----EENRKIDIQAKRVQARLDNL 310
L+ K + S D AL EL+ + KK E + E++R + ++ Q R+ +
Sbjct: 896 LEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLM 955
Query: 311 QRKYE 315
YE
Sbjct: 956 ADNYE 960
Score = 29.6 bits (65), Expect = 9.3
Identities = 35/162 (21%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 180 IYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTR 239
I+ E +++ +Q E Q + LQ R + QL + ++ + V E
Sbjct: 210 IWKEQYRV---VQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEEN 266
Query: 240 FQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKI--D 297
FQ + +H+ + KE LR + + ++ +T K+ LN E +K+
Sbjct: 267 FQRLHAEHERQA-----------KELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEM 315
Query: 298 IQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEK 339
+Q+K + A+ + + +RL + VH ++SL ++K
Sbjct: 316 LQSKGLSAK----ATEEDHERTRRLAEAEMHVHHLESLLEQK 353
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/110 (25%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
Query: 204 ELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEV------EHLTEV 257
EL++ E L ERE L L ++ + ++ + +K+Q+ + E L +V
Sbjct: 941 ELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV 1000
Query: 258 LKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARL 307
+ E+ KE L + D+LK+ + +K+ NE ++ ++++AK V +L
Sbjct: 1001 ISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKL 1050
Score = 36.6 bits (83), Expect = 0.076
Identities = 73/331 (22%), Positives = 139/331 (41%), Gaps = 46/331 (13%)
Query: 57 SGDKVGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDSFHDLKKQETEEEL----IEN 112
SG K SS K E+ PL ++ L D DS + K+E + L +E
Sbjct: 206 SGKKKASSKKQKTENVFVDEPLIHATTYIP---LMDNADSSPVVDKREVIDLLKPDQVEG 262
Query: 113 DYRVSTSKITKQSFKEIEKVALPTNTTS------SRPRTECCSDAGDSPLKPVSCPKSKA 166
+ T K+ ++ KE +V S S C D + K+
Sbjct: 263 IQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEKSGVIQDALKKS 322
Query: 167 SD-KRSLLPHQISQIYDELFQIH-----LKLQCETAAQQKFAEE-------LQKRERF-L 212
S + + L HQ+ + L + K +C+ Q+ E+ + ++R
Sbjct: 323 SKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGT 382
Query: 213 LEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTE---VLKEK-NKETKRL 268
LE+E +F+++ +S + +++ +FQ ++EQ +AE+ HL + +L++ + T +L
Sbjct: 383 LEKEHNVFQNKIHVSYQE--TQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQL 440
Query: 269 RSSFDA-LKELNDTLKKQLNEASEENRKI---DIQAK-------RVQARLDNLQRKYEFM 317
S A L +L + +NE +E+ K+ ++Q K +++ +L +R++E
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWE-- 498
Query: 318 TIQRLKGSSHAVHEMKSLKQEKAPVSKTYKV 348
+Q A HE + V+K +V
Sbjct: 499 EVQSYIRKRTAEHEAAQQDLQSKFVAKENEV 529
Score = 31.6 bits (70), Expect = 2.5
Identities = 71/331 (21%), Positives = 126/331 (38%), Gaps = 61/331 (18%)
Query: 256 EVLKEKNKETKRLRSSFDALKELNDTLKKQ------LNEASEENRKIDIQAKRVQARLDN 309
EVL ++ +E K + + D K KK+ L+E+ E+ D + A D+
Sbjct: 36 EVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDD 95
Query: 310 LQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPV--------SKTYKVPLNGQVYELLTVF 361
++ +S +V E K ++++ PV S K+P G+ E + V
Sbjct: 96 QVAPVPLNVVE----TSSSVRERKKKEKKQKPVLEEQVIKESDASKIP--GKKVEPVPVT 149
Query: 362 MDWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQLQWMPFVNIKL 421
E+ KKP K + +D Q+K V+ L + +++ + +P L
Sbjct: 150 KQ--------PTPPSEAAASKKKPGQKKSKNGSDDQDKKVETLMVPSKRQEALP-----L 196
Query: 422 HEPFVKFIYWSLRQLDAGAQHSTMTSTLRR-----LGEDIFKGVVTKGIQDNSPQHSVEN 476
H+ + ++G+ +S ++ + E + + DN+ V +
Sbjct: 197 HQE---------TKQESGSGKKKASSKKQKTENVFVDEPLIHATTYIPLMDNADSSPVVD 247
Query: 477 KPKTAAFFKSSNLPLRFLSTLIVLKTVTQADYLAQAFDSLCLDLKTEEGKTLFLEYQAV- 535
K + K + S LKT T + F L LKT +F E +A+
Sbjct: 248 KREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKT----MMFSEDEALC 303
Query: 536 ---------PVILSHLRISSKGLLSNVIDSL 557
VI L+ SSKG L+ +I L
Sbjct: 304 VVDLLKEKSGVIQDALKKSSKGELTTLIHQL 334
Score = 30.8 bits (68), Expect = 4.2
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 22/151 (14%)
Query: 203 EELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEV------EHLTE 256
E++ + L E+E+ L L ++ E + Q + + + E E L
Sbjct: 874 EQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEI 933
Query: 257 VLKEKNKETKRLRSSFDALKELNDTLKKQ---LNEASEENRKIDIQAKRVQARLDNLQRK 313
VLKEK E KRL + LKE L + L + +EN+ Q + Q + N Q+
Sbjct: 934 VLKEKENELKRLEA---MLKERESDLSSKTQLLQDVQDENKLFKSQIE--QLKQQNYQQA 988
Query: 314 YEF--------MTIQRLKGSSHAVHEMKSLK 336
F + +R K S +E+ SLK
Sbjct: 989 SSFPPHEELLKVISEREKEISGLWNELDSLK 1019
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/148 (22%), Positives = 76/148 (51%), Gaps = 15/148 (10%)
Query: 203 EELQKRERFLLEREQLLFRHENAL----SKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVL 258
E+++++E + E+E+ ++R E + KI+ EEE+ + + I+EQ + E +
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 259 KEKNKETKRLRS-------SFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQ 311
K+ ++ +++R + ++EL + ++ Q + E K+ + +++Q + + +Q
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 312 RKYEFMTIQRLKGSSHAVHEMKSLKQEK 339
R+ E + Q K + K LKQE+
Sbjct: 473 RQEEKIQEQEEK----TWRQEKLLKQEE 496
Score = 39.7 bits (91), Expect = 0.009
Identities = 44/219 (20%), Positives = 97/219 (44%), Gaps = 27/219 (12%)
Query: 99 DLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKP 158
D K QE EEE+ + KI +Q K EK+ R E D ++
Sbjct: 380 DEKIQEQEEEMWRQE-----EKIREQEEKRQEKMW----------RQEKKMREQDEKIRE 424
Query: 159 VSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQL 218
+ +K L + ++L ++ K+Q E Q+ E++Q++E + E+E+
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 219 LFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKEL 278
+R E L + + + E+ +E+ + E + E ++ ++ ++++ + ++E
Sbjct: 485 TWRQEKLLKQEEKIWEQ--------EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Query: 279 NDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFM 317
L +Q + E+ +++ + ++ RL L +K E +
Sbjct: 537 EVRLWQQEEKMQEQ----EVRLQELEERLGKLGQKAELL 571
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/148 (22%), Positives = 76/148 (51%), Gaps = 15/148 (10%)
Query: 203 EELQKRERFLLEREQLLFRHENAL----SKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVL 258
E+++++E + E+E+ ++R E + KI+ EEE+ + + I+EQ + E +
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 259 KEKNKETKRLRS-------SFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQ 311
K+ ++ +++R + ++EL + ++ Q + E K+ + +++Q + + +Q
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 312 RKYEFMTIQRLKGSSHAVHEMKSLKQEK 339
R+ E + Q K + K LKQE+
Sbjct: 473 RQEEKIQEQEEK----TWRQEKLLKQEE 496
Score = 39.7 bits (91), Expect = 0.009
Identities = 44/219 (20%), Positives = 97/219 (44%), Gaps = 27/219 (12%)
Query: 99 DLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKP 158
D K QE EEE+ + KI +Q K EK+ R E D ++
Sbjct: 380 DEKIQEQEEEMWRQE-----EKIREQEEKRQEKMW----------RQEKKMREQDEKIRE 424
Query: 159 VSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQL 218
+ +K L + ++L ++ K+Q E Q+ E++Q++E + E+E+
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 219 LFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKEL 278
+R E L + + + E+ +E+ + E + E ++ ++ ++++ + ++E
Sbjct: 485 TWRQEKLLKQEEKIWEQ--------EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Query: 279 NDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFM 317
L +Q + E+ +++ + ++ RL L +K E +
Sbjct: 537 EVRLWQQEEKMQEQ----EVRLQELEERLGKLGQKAELL 571
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/124 (25%), Positives = 60/124 (48%), Gaps = 16/124 (12%)
Query: 190 KLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDA 249
K++ E A ++ LQ+ LLE+ + + E+ +R+ ++++H A
Sbjct: 323 KMELEVAERKLSFHNLQEEMHHLLEQ----------FEQAGQAQAELESRYSALEQKHKA 372
Query: 250 EVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDN 309
E+E T + K + L+S+ DALK+ N L + NE + ++ A+ +Q D
Sbjct: 373 EMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQS------AQTIQQLEDQ 426
Query: 310 LQRK 313
LQ+K
Sbjct: 427 LQQK 430
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/250 (21%), Positives = 108/250 (43%), Gaps = 33/250 (13%)
Query: 176 QISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENA----LSKIKG 231
+I + +EL + L+ ++ + +LQ +E +LE + + RH ++ LS+
Sbjct: 811 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERV-RHISSKVEELSQALS 869
Query: 232 VEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSF-DALKELND---------- 280
+E +T+ + + +VE L + ++EK+++ + S + + +LN+
Sbjct: 870 QKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIK 929
Query: 281 TLKKQLNEASEENRKIDIQAKRVQARLDN-----LQRKYEFMTIQRLKGSSHAVHEMKSL 335
TLK+QLN S +AK+ Q DN L++ Y+ M+ HE L
Sbjct: 930 TLKEQLNLLSRAE-----EAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLL 984
Query: 336 KQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESG----MDGKKPQLKFAS 391
K+E + + L + L V + L+ +K E + ++ +++
Sbjct: 985 KKENEQRKRKLQAALINRKELLQRVSR---LEEELANLKDESKKEIPLSETERGEVEEDK 1041
Query: 392 QRNDIQEKCV 401
+ + EKCV
Sbjct: 1042 ENKEYSEKCV 1051
Score = 40.8 bits (94), Expect = 0.004
Identities = 66/284 (23%), Positives = 115/284 (40%), Gaps = 53/284 (18%)
Query: 91 DDELDSFHDLKKQETEEELI---ENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTEC 147
D E+ +L QE EE ++ EN V + ++ K I+K +
Sbjct: 2407 DKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL------- 2459
Query: 148 CSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCE--------TAAQQ 199
DS +K +S S +D+ ++ Y +L + HL + E A
Sbjct: 2460 -----DSFVKSMS---SLQNDRDRIVGD-----YQQLEERHLSIILEKDQLIQEAAAENN 2506
Query: 200 KFAEELQ---------KRERFLLEREQLLFRHE-NALSKIKGVEEEVLTRFQIIKEQHDA 249
K EE++ E L+ E + +R + N + IK +++ L Q+ Q +
Sbjct: 2507 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQL---QQNK 2563
Query: 250 EVEH----LTEVLKEKNKETKRLRSSFDALKELNDTLKKQLN----EASEENRKIDIQAK 301
E+E+ L E LKE + + LR SF+AL+E L K++ S+ R++ +
Sbjct: 2564 ELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQE 2623
Query: 302 RVQARLDNLQRKYEFMTIQRLKG-SSHAVHEMKSLKQEKAPVSK 344
L + Q K + + RL S + + L++E V K
Sbjct: 2624 EGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2667
Score = 39.7 bits (91), Expect = 0.009
Identities = 48/215 (22%), Positives = 100/215 (46%), Gaps = 12/215 (5%)
Query: 173 LPHQISQIYDELFQIHLKLQCETAAQ-QKFAEELQKRERFLLEREQLLFRHENALSKIKG 231
L Q + + + Q+ ++L CE + ++ EE + +++ + + L + AL + K
Sbjct: 1443 LEMQAKEHDERIKQLQVEL-CEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKS 1501
Query: 232 VEEEV-LTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEAS 290
++EE+ L R I E+ + + + +NKE + L+E D L +++ +
Sbjct: 1502 LQEELSLARGTI--ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSL 1559
Query: 291 EENRKIDIQAKRVQARLDNLQRKYEFMT--IQRLKGSSHAVHEMKSLKQEKAPVSKTYKV 348
EN+ + + ++ L+ L E + I+ LK S A E +++ + K Y++
Sbjct: 1560 LENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIA--ESTEWQEKHKELQKEYEI 1617
Query: 349 PLNGQVYELLTVFMDWISDHHLSKVKHEESGMDGK 383
L Q YE ++ + I H + V+ E+ + GK
Sbjct: 1618 LL--QSYENVSNEAERI-QHVVEAVRQEKQELYGK 1649
Score = 35.4 bits (80), Expect = 0.17
Identities = 39/210 (18%), Positives = 85/210 (40%), Gaps = 10/210 (4%)
Query: 98 HDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLK 157
H L+++E ++ + ++ QS E+E+ + + A S +
Sbjct: 151 HKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQ 210
Query: 158 PVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQK---FAEELQKRERFLLE 214
+ +K + Q+ DEL Q+ + ET QQK +L++ E L+
Sbjct: 211 AEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVG 270
Query: 215 REQLLFRHENALSKIKGVEEEVLTRFQIIKEQH-------DAEVEHLTEVLKEKNKETKR 267
R Q++ + L+ + + + + Q ++ +H + E E +L++ E
Sbjct: 271 RAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAE 330
Query: 268 LRSSFDALKELNDTLKKQLNEASEENRKID 297
+ SF L+E L +Q +A + +++
Sbjct: 331 RKLSFHNLQEEMHHLLEQFEQAGQAQAELE 360
Score = 35.4 bits (80), Expect = 0.17
Identities = 55/261 (21%), Positives = 102/261 (39%), Gaps = 18/261 (6%)
Query: 90 LDDELDSFHDL-KKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECC 148
L +LD L K+E + + + +TK + IE+ L + + E
Sbjct: 1390 LQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL---IKALHTQLEMQ 1446
Query: 149 SDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQC------ETAAQQKFA 202
+ D +K + + K P +I + QI KLQ E + K
Sbjct: 1447 AKEHDERIKQLQVELCEMKQK----PEEIGEESRAKQQIQRKLQAALISRKEALKENKSL 1502
Query: 203 EELQKRERFLLER-EQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEK 261
+E R +ER + L E+ +S ++ VL R +++E+ D + + L E
Sbjct: 1503 QEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN 1562
Query: 262 NKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQR 321
+ S AL+ L + +K + E ++ Q + LQ++YE +
Sbjct: 1563 QSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSY 1622
Query: 322 LKGSSHA---VHEMKSLKQEK 339
S+ A H +++++QEK
Sbjct: 1623 ENVSNEAERIQHVVEAVRQEK 1643
Score = 35.0 bits (79), Expect = 0.22
Identities = 21/87 (24%), Positives = 42/87 (48%)
Query: 209 ERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRL 268
E + E E+ + E +++ +E LT + I ++ + HL E LK++ + RL
Sbjct: 1156 EHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRL 1215
Query: 269 RSSFDALKELNDTLKKQLNEASEENRK 295
+ FD + N+ + QL + + R+
Sbjct: 1216 QEQFDEQSKENENIGDQLRQLQIQVRE 1242
Score = 35.0 bits (79), Expect = 0.22
Identities = 59/237 (24%), Positives = 106/237 (44%), Gaps = 41/237 (17%)
Query: 200 KFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDA---EVEHLTE 256
K +ELQ + + + Q+ + E+ +++ EE+ L + ++E+ DA E HL E
Sbjct: 2100 KLKKELQSNKESV--KSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEE 2157
Query: 257 VLKE-------KNKETKRLRSSFD-----------ALKELNDTLKKQLNEASEENRKID- 297
+ E K+KE ++L+ + D ++ L D + ++EA + RK
Sbjct: 2158 TIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSD 2217
Query: 298 -IQAKRVQARL--DNL-----QRKYEFMTIQRLKGSSHAVHEMKSLKQEKA--PVSKTYK 347
IQ+K + RL DN Q + + ++ LK + + K + + KA V K
Sbjct: 2218 AIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQK 2277
Query: 348 V--PLNGQVYELLTVFMDWISDHHLS--KVKHEESGMDGKKPQLKFASQRNDIQEKC 400
V L G+ ELL+ + +H S ++ ES + K QL + ++ EKC
Sbjct: 2278 VCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQL---TDLSNSLEKC 2331
Score = 34.3 bits (77), Expect = 0.38
Identities = 46/276 (16%), Positives = 116/276 (42%), Gaps = 34/276 (12%)
Query: 100 LKKQETEEELIENDYRVSTSKITK-QSFKEIEKVALPTNTTSSRPRTE-----CCSDAGD 153
L+++ T+ L+ + S++TK + E EK L + C D D
Sbjct: 1887 LQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTD 1946
Query: 154 SPLKPV----------SCPKSKASDKRSLLPH------QISQIYDELFQIHLKLQCETAA 197
+ +K C +K+ L+ +I + Y E Q K +
Sbjct: 1947 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSH 2006
Query: 198 QQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEV 257
++ E L+++++ + + ++ R++ +S + E + + ++ + ++E E
Sbjct: 2007 AKELQELLKEKQQEVKQLQKDCIRYQEKISAL----ERTVKALEFVQTESQKDLEITKEN 2062
Query: 258 LKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKI--DIQAKR------VQARLDN 309
L + + K+ ++ + K L D + + +N K+ ++Q+ + ++ + ++
Sbjct: 2063 LAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDED 2122
Query: 310 LQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKT 345
L+R+ E + LK + ++ +L++EK + +T
Sbjct: 2123 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEET 2158
Score = 33.5 bits (75), Expect = 0.65
Identities = 52/253 (20%), Positives = 108/253 (42%), Gaps = 22/253 (8%)
Query: 170 RSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKI 229
RSLL +Q + + L L+ T ++K +E++ + + L K
Sbjct: 1557 RSLLENQ--SLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQK- 1613
Query: 230 KGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKET-KRLRSSFDALKELNDTLKKQLNE 288
E E+L + ++H+ E ++++ +E +LRS+ KE L++ E
Sbjct: 1614 ---EYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQE 1670
Query: 289 ASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMK-------SLKQEKAP 341
E K+ AK Q ++ L+ + + + + A M+ S+K+E
Sbjct: 1671 MEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELER 1730
Query: 342 VSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDGKKPQLKFASQRND----IQ 397
V Y+ + ++ L D +S+ + +KH+ G K+ L+ A++++D +
Sbjct: 1731 VKMEYET--LSKKFQSLMSEKDSLSE-EVQDLKHQIEGNVSKQANLE-ATEKHDNQTNVT 1786
Query: 398 EKCVKLLPLMTEQ 410
E+ + +P TE+
Sbjct: 1787 EEGTQSIPGETEE 1799
Score = 33.5 bits (75), Expect = 0.65
Identities = 46/218 (21%), Positives = 95/218 (43%), Gaps = 15/218 (6%)
Query: 103 QETEEELIENDYRVSTSKITKQSFKEIEKVAL-PTNTTSSRPRTECCSDAGDSPLKPVSC 161
+E +++L++ +V S+I K+ ++I+ P N + ++ E + +K +
Sbjct: 1969 EEEKQQLVKEKTKVE-SEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEK-QQEVKQLQK 2026
Query: 162 PKSKASDKRSLLPHQIS--QIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLL 219
+ +K S L + + Q L++ E AQ E +K + L + LL
Sbjct: 2027 DCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA--VEHRKKAQAELASFKVLL 2084
Query: 220 FRHENALSKIKGVEEEVLTRFQIIKE-------QHDAEVEHLTEVLKEKN-KETKRLRSS 271
++ +++ ++ Q KE Q D ++E E +EK+ KE K ++
Sbjct: 2085 DDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2144
Query: 272 FDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDN 309
DAL+ L++ + E K D + +++Q LD+
Sbjct: 2145 LDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2182
Score = 30.4 bits (67), Expect = 5.5
Identities = 20/110 (18%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Query: 232 VEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASE 291
++++V Q ++ +++E + E +L S +LK+ L L + E
Sbjct: 2274 LQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKE 2333
Query: 292 ENRKIDIQAKRVQARLDNLQRKYEFM--TIQRLKGSSHAVHEMKSLKQEK 339
+ ++ ++ +A + N + YE + +Q + + +HE ++K++K
Sbjct: 2334 QKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQK 2383
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 44.3 bits (103), Expect = 4e-04
Identities = 33/163 (20%), Positives = 85/163 (52%), Gaps = 13/163 (7%)
Query: 190 KLQCETAAQQKFAEELQKRERFLLEREQLLFRHENAL----SKIKGVEEEVLTRFQI-IK 244
K+Q + ++ E+++++E + E+E+ + R E + KI+ +EE++ + +I +
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362
Query: 245 EQHDAEVEHLTEVLKEKNKETK------RLRSSFDALKELNDTLKKQLNEASEENRKIDI 298
E+ E E + E K + +E K ++R + ++E + +++Q + E+ K+
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE 422
Query: 299 QAKRVQARLDNLQRKYEFMTIQ--RLKGSSHAVHEMKSLKQEK 339
Q + +Q + + ++R+ E + Q +++ + E + + QE+
Sbjct: 423 QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,336,108
Number of Sequences: 37866
Number of extensions: 1001985
Number of successful extensions: 6380
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 569
Number of HSP's that attempted gapping in prelim test: 4636
Number of HSP's gapped (non-prelim): 1912
length of query: 665
length of database: 18,247,518
effective HSP length: 109
effective length of query: 556
effective length of database: 14,120,124
effective search space: 7850788944
effective search space used: 7850788944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.