Guide to the Human Genome
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Search of human proteins with 213972593

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|213972593 TPTE and PTEN homologous inositol lipid
phosphatase isoform delta [Homo sapiens]
         (411 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase...   845   0.0  
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase...   785   0.0  
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase...   729   0.0  
gi|40549435 transmembrane phosphatase with tensin homology isofo...   620   e-178
gi|40549433 transmembrane phosphatase with tensin homology isofo...   620   e-178
gi|109689707 transmembrane phosphatase with tensin homology isof...   620   e-178
gi|73765544 phosphatase and tensin homolog [Homo sapiens]             221   7e-58
gi|157384971 cyclin G associated kinase [Homo sapiens]                122   6e-28
gi|65288071 tensin 3 [Homo sapiens]                                   119   7e-27
gi|66529407 tensin [Homo sapiens]                                     114   1e-25
gi|239756009 PREDICTED: similar to transmembrane phosphoinositid...   109   5e-24
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap...   103   4e-22
gi|38787970 tensin like C1 domain containing phosphatase isoform...   100   4e-21
gi|38787957 tensin like C1 domain containing phosphatase isoform...   100   4e-21
gi|38787941 tensin like C1 domain containing phosphatase isoform...   100   4e-21
gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]                  41   0.002
gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]                    41   0.002
gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]                   41   0.002
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...    40   0.005
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...    40   0.005
gi|205277447 dual specificity phosphatase 11 [Homo sapiens]            39   0.011
gi|241896926 protein tyrosine phosphatase, receptor type, H isof...    36   0.056
gi|241896924 protein tyrosine phosphatase, receptor type, H isof...    36   0.056
gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]                   36   0.073
gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]                   36   0.073
gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]                   36   0.073
gi|30089952 protein tyrosine phosphatase domain containing 1 pro...    36   0.073
gi|30089950 protein tyrosine phosphatase domain containing 1 pro...    36   0.073
gi|148728162 protein tyrosine phosphatase, receptor type, J isof...    35   0.12 
gi|148224884 protein tyrosine phosphatase, mitochondrial 1 isofo...    33   0.47 

>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
           isoform delta [Homo sapiens]
          Length = 411

 Score =  845 bits (2182), Expect = 0.0
 Identities = 411/411 (100%), Positives = 411/411 (100%)

Query: 1   MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE 60
           MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE
Sbjct: 1   MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE 60

Query: 61  WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM 120
           WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM
Sbjct: 61  WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM 120

Query: 121 SFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNV 180
           SFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNV
Sbjct: 121 SFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNV 180

Query: 181 PTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYF 240
           PTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYF
Sbjct: 181 PTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYF 240

Query: 241 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVC 300
           GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVC
Sbjct: 241 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVC 300

Query: 301 DLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYY 360
           DLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYY
Sbjct: 301 DLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYY 360

Query: 361 DNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK 411
           DNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
Sbjct: 361 DNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK 411


>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
           isoform alpha [Homo sapiens]
          Length = 445

 Score =  785 bits (2026), Expect = 0.0
 Identities = 393/445 (88%), Positives = 397/445 (89%), Gaps = 34/445 (7%)

Query: 1   MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLE----------RLSKFEV 50
           MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISK +             L+    
Sbjct: 1   MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRIFGVFLVLLDVTLLLADLIF 60

Query: 51  EDAENVASYE------------------------WTHLVRLLRLIILIRIFHLLHQKRQL 86
            D++     E                        WTHLVRLLRLIILIRIFHLLHQKRQL
Sbjct: 61  TDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVEGWTHLVRLLRLIILIRIFHLLHQKRQL 120

Query: 87  EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH 146
           EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH
Sbjct: 121 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH 180

Query: 147 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA 206
           RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA
Sbjct: 181 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA 240

Query: 207 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG 266
           IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG
Sbjct: 241 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG 300

Query: 267 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH 326
           YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH
Sbjct: 301 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH 360

Query: 327 DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL 386
           DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL
Sbjct: 361 DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL 420

Query: 387 DNPHKQKAWKIYPPEFAVEILFGEK 411
           DNPHKQKAWKIYPPEFAVEILFGEK
Sbjct: 421 DNPHKQKAWKIYPPEFAVEILFGEK 445


>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
           isoform gamma [Homo sapiens]
          Length = 522

 Score =  729 bits (1883), Expect = 0.0
 Identities = 353/364 (96%), Positives = 357/364 (98%), Gaps = 2/364 (0%)

Query: 48  FEVEDAENVASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFD 107
           F+++   N+    WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFD
Sbjct: 161 FDIKLLRNIP--RWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFD 218

Query: 108 LDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 167
           LDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH
Sbjct: 219 LDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 278

Query: 168 NRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIAS 227
           NRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIAS
Sbjct: 279 NRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIAS 338

Query: 228 EIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFI 287
           EIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFI
Sbjct: 339 EIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFI 398

Query: 288 KRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDV 347
           KRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDV
Sbjct: 399 KRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDV 458

Query: 348 KVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEIL 407
           KVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEIL
Sbjct: 459 KVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEIL 518

Query: 408 FGEK 411
           FGEK
Sbjct: 519 FGEK 522



 Score =  119 bits (298), Expect = 5e-27
 Identities = 59/60 (98%), Positives = 60/60 (100%)

Query: 1  MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE 60
          MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASY+
Sbjct: 1  MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYD 60


>gi|40549435 transmembrane phosphatase with tensin homology isoform
           gamma [Homo sapiens]
          Length = 513

 Score =  620 bits (1600), Expect = e-178
 Identities = 303/364 (83%), Positives = 327/364 (89%), Gaps = 2/364 (0%)

Query: 48  FEVEDAENVASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFD 107
           F+++   N+    WTHL+RLLRLIIL+RIFHL HQKRQLEKL+RR VSENKRRYTRDGFD
Sbjct: 141 FDIKLLRNIP--RWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFD 198

Query: 108 LDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 167
           LDLTYVTERIIAMSFPSSGRQSFYRNPI+EVVRFLDKKHRNHYRVYNLCSERAYDPKHFH
Sbjct: 199 LDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 258

Query: 168 NRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIAS 227
           NRV RIMIDDHNVPTLH+MVVFTKEVNEWMAQDLENIVAIHCKGG  RTGTMVCA LIAS
Sbjct: 259 NRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIAS 318

Query: 228 EIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFI 287
           EI  TA+ESLYYFGERRT+KTHS KFQGVETPSQ RYV YFAQVKHLYNWNLPPRRILFI
Sbjct: 319 EICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFI 378

Query: 288 KRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDV 347
           K FIIYSI   V DLK+Q+ MEKKVVFS+ SLG CS+L +I TDKILI+V+DG PLYDDV
Sbjct: 379 KHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDV 438

Query: 348 KVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEIL 407
           KVQFF SNLP YYDNC F+FW +TSFI+NNRL LP+NELDN HKQKA +IYP +FAVEIL
Sbjct: 439 KVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEIL 498

Query: 408 FGEK 411
           FGEK
Sbjct: 499 FGEK 502



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 18/21 (85%), Positives = 20/21 (95%)

Query: 2  NESPQTNEFKGTTEEAPAKES 22
          N+SPQT+EFKG TEEAPAKES
Sbjct: 20 NDSPQTSEFKGATEEAPAKES 40



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 18/40 (45%), Positives = 22/40 (55%)

Query: 1  MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKS 40
          MNESP   +  G   E    +SP TSEFKGA   +P  +S
Sbjct: 1  MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKES 40


>gi|40549433 transmembrane phosphatase with tensin homology isoform
           beta [Homo sapiens]
          Length = 533

 Score =  620 bits (1600), Expect = e-178
 Identities = 303/364 (83%), Positives = 327/364 (89%), Gaps = 2/364 (0%)

Query: 48  FEVEDAENVASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFD 107
           F+++   N+    WTHL+RLLRLIIL+RIFHL HQKRQLEKL+RR VSENKRRYTRDGFD
Sbjct: 161 FDIKLLRNIP--RWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFD 218

Query: 108 LDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 167
           LDLTYVTERIIAMSFPSSGRQSFYRNPI+EVVRFLDKKHRNHYRVYNLCSERAYDPKHFH
Sbjct: 219 LDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 278

Query: 168 NRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIAS 227
           NRV RIMIDDHNVPTLH+MVVFTKEVNEWMAQDLENIVAIHCKGG  RTGTMVCA LIAS
Sbjct: 279 NRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIAS 338

Query: 228 EIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFI 287
           EI  TA+ESLYYFGERRT+KTHS KFQGVETPSQ RYV YFAQVKHLYNWNLPPRRILFI
Sbjct: 339 EICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFI 398

Query: 288 KRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDV 347
           K FIIYSI   V DLK+Q+ MEKKVVFS+ SLG CS+L +I TDKILI+V+DG PLYDDV
Sbjct: 399 KHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDV 458

Query: 348 KVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEIL 407
           KVQFF SNLP YYDNC F+FW +TSFI+NNRL LP+NELDN HKQKA +IYP +FAVEIL
Sbjct: 459 KVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEIL 518

Query: 408 FGEK 411
           FGEK
Sbjct: 519 FGEK 522



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 35/60 (58%), Positives = 41/60 (68%)

Query: 1  MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE 60
          MNESP   +  G   E    +SP TSEFKGA   +P  +S+L RLSKFEVEDAENVASY+
Sbjct: 1  MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESVLARLSKFEVEDAENVASYD 60


>gi|109689707 transmembrane phosphatase with tensin homology isoform
           alpha [Homo sapiens]
          Length = 551

 Score =  620 bits (1600), Expect = e-178
 Identities = 303/364 (83%), Positives = 327/364 (89%), Gaps = 2/364 (0%)

Query: 48  FEVEDAENVASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFD 107
           F+++   N+    WTHL+RLLRLIIL+RIFHL HQKRQLEKL+RR VSENKRRYTRDGFD
Sbjct: 179 FDIKLLRNIP--RWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFD 236

Query: 108 LDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 167
           LDLTYVTERIIAMSFPSSGRQSFYRNPI+EVVRFLDKKHRNHYRVYNLCSERAYDPKHFH
Sbjct: 237 LDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFH 296

Query: 168 NRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIAS 227
           NRV RIMIDDHNVPTLH+MVVFTKEVNEWMAQDLENIVAIHCKGG  RTGTMVCA LIAS
Sbjct: 297 NRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIAS 356

Query: 228 EIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFI 287
           EI  TA+ESLYYFGERRT+KTHS KFQGVETPSQ RYV YFAQVKHLYNWNLPPRRILFI
Sbjct: 357 EICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFI 416

Query: 288 KRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDV 347
           K FIIYSI   V DLK+Q+ MEKKVVFS+ SLG CS+L +I TDKILI+V+DG PLYDDV
Sbjct: 417 KHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDV 476

Query: 348 KVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEIL 407
           KVQFF SNLP YYDNC F+FW +TSFI+NNRL LP+NELDN HKQKA +IYP +FAVEIL
Sbjct: 477 KVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEIL 536

Query: 408 FGEK 411
           FGEK
Sbjct: 537 FGEK 540



 Score =  104 bits (260), Expect = 1e-22
 Identities = 51/59 (86%), Positives = 56/59 (94%)

Query: 2  NESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE 60
          N+SPQT+EFKG TEEAPAKESPHTSEFKGAA VSPIS+S+L RLSKFEVEDAENVASY+
Sbjct: 20 NDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVLARLSKFEVEDAENVASYD 78


>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
          Length = 403

 Score =  221 bits (564), Expect = 7e-58
 Identities = 133/358 (37%), Positives = 191/358 (53%), Gaps = 52/358 (14%)

Query: 89  LMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRN 148
           +++ +VS NKRRY  DGFDLDLTY+   IIAM FP+   +  YRN I++VVRFLD KH+N
Sbjct: 4   IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63

Query: 149 HYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIH 208
           HY++YNLC+ER YD   F+ RV++   +DHN P L  +  F +++++W+++D  ++ AIH
Sbjct: 64  HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123

Query: 209 CKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYF 268
           CK GKGRTG M+CA L+    FL A+E+L ++GE RT        +GV  PSQ RYV Y+
Sbjct: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYY 178

Query: 269 AQV--KHLYNWNLPPRRILFIKRFI--IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSI 324
           + +   HL   +  P  +LF K     I    G  C+ +  V   K  ++SS S      
Sbjct: 179 SYLLKNHL---DYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPT--- 232

Query: 325 LHDIETDKILINVYDGP-PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFI--------- 374
                 DK +   +  P P+  D+KV+FF         +  F FW NT FI         
Sbjct: 233 ---RREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289

Query: 375 -QNNRLC-----------------------LPRNELDNPHKQKAWKIYPPEFAVEILF 408
            +N  LC                       L +N+LD  +K KA + + P F V++ F
Sbjct: 290 VENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347


>gi|157384971 cyclin G associated kinase [Homo sapiens]
          Length = 1311

 Score =  122 bits (306), Expect = 6e-28
 Identities = 64/165 (38%), Positives = 89/165 (53%), Gaps = 9/165 (5%)

Query: 107 DLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHF 166
           DLD++Y+T RI  MSFP+ G +S  +N IE+V  FLD KH  HY VYNL S R Y P  F
Sbjct: 407 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNL-SPRTYRPSRF 465

Query: 167 HNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIA 226
           HNRVS         P LH +    + ++ W+ QD +N+  +HC  G+  +   VC+ L  
Sbjct: 466 HNRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCF 525

Query: 227 SEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV 271
             +F TAE ++Y F  +R          G+  PS  RY+ Y   +
Sbjct: 526 CRLFSTAEAAVYMFSMKRCP-------PGI-WPSHKRYIEYMCDM 562


>gi|65288071 tensin 3 [Homo sapiens]
          Length = 1445

 Score =  119 bits (297), Expect = 7e-27
 Identities = 86/310 (27%), Positives = 149/310 (48%), Gaps = 19/310 (6%)

Query: 104 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDP 163
           +G  LDLTY+TERIIA+SFP+   +  Y + ++EV R L  KH ++Y V NL SE+ YD 
Sbjct: 3   EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61

Query: 164 KHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCAL 223
              + ++  +   + + P L +M    K    W+  +L+++V IHC+GGKGR G ++ + 
Sbjct: 62  TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121

Query: 224 LIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPR 282
           +  + +  +A+++L  F  +   K + +K   +  PSQ RYV + +  +      N  P 
Sbjct: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177

Query: 283 RILFIKRFIIYSI----RGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVY 338
             LF+   I++       G VC   +++    + V++S        +      +I I + 
Sbjct: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYN----VGPENPSRICIVIE 231

Query: 339 DGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIY 398
               L  DV V+ +         +  F   F+T  +Q   L   + +LDN  K      +
Sbjct: 232 PAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR---F 288

Query: 399 PPEFAVEILF 408
           P    VE++F
Sbjct: 289 PDYGKVELVF 298


>gi|66529407 tensin [Homo sapiens]
          Length = 1735

 Score =  114 bits (286), Expect = 1e-25
 Identities = 90/314 (28%), Positives = 150/314 (47%), Gaps = 19/314 (6%)

Query: 100 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSER 159
           R   D  +LDL YVTERIIA+SFPS+  +  +R+ + EV + L  KH  +Y ++NL SER
Sbjct: 5   RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63

Query: 160 AYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTM 219
             D    H +V      D + P L ++    K ++ W+  D  N+V +H KG +GR G +
Sbjct: 64  RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123

Query: 220 VCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWN 278
           + A +  S I  +A+++L  F  +R    + +K   +  PSQ RYV YF+  +      N
Sbjct: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180

Query: 279 LPPRRILFIKRFIIYSIRG----DVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKIL 334
             P   LF+   I++ I        C   +++    + V++S   G  +I  D +T  + 
Sbjct: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTS---GIYNIPGDSQT-SVC 233

Query: 335 INVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKA 394
           I +  G  L  D+ ++ +         +  F   F+T  I +  +   + +LD+  K   
Sbjct: 234 ITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR 293

Query: 395 WKIYPPEFAVEILF 408
              +P    VE +F
Sbjct: 294 ---FPEYGKVEFVF 304


>gi|239756009 PREDICTED: similar to transmembrane phosphoinositide
           3-phosphatase and tensin homolog 2, partial [Homo
           sapiens]
          Length = 99

 Score =  109 bits (272), Expect = 5e-24
 Identities = 50/56 (89%), Positives = 51/56 (91%)

Query: 158 ERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 213
           ERAYDPKHFHNRVSRIMIDDHNVPTL EMV F+KEV EWMAQD ENIV IHCKGGK
Sbjct: 29  ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84


>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
           sapiens]
          Length = 913

 Score =  103 bits (256), Expect = 4e-22
 Identities = 57/178 (32%), Positives = 90/178 (50%), Gaps = 11/178 (6%)

Query: 94  VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVY 153
           V ++   YT+   DLD TYVT RII MSFP       +RN ++++  FLD +H +HY VY
Sbjct: 52  VIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVY 109

Query: 154 NLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 213
           NL S ++Y    FH+RVS         P+LH +    + +  W+ Q+ +N+  +HC  G+
Sbjct: 110 NL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGR 168

Query: 214 GRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV 271
             +  +V A+ I   ++ T   ++     +R     S        PS  RY+GY   +
Sbjct: 169 AASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLS--------PSHRRYLGYMCDL 218


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)

Query: 106 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 165
           +DLDLTYVTERI+A +FP+   +  +R  + E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 5   WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 63

Query: 166 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 225
            + +V      + + P L ++    K +  W++ D +++V ++CKG KG+ G +V A + 
Sbjct: 64  LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 123

Query: 226 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 284
            S+I   A+++L     R   K   +K      PSQ RY+ YF+  +      N  P   
Sbjct: 124 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 177

Query: 285 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 341
           LF+   +I  +         Q  ++   ++ S  L   S ++ I      ++ I++    
Sbjct: 178 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 234

Query: 342 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 399
            L  DV V  +            F   F+T  I   +L  P+++LD     +AW  + +P
Sbjct: 235 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 289

Query: 400 PEFAVEILF 408
            + +VE +F
Sbjct: 290 FQASVEFVF 298


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
           [Homo sapiens]
          Length = 1409

 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)

Query: 106 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 165
           +DLDLTYVTERI+A +FP+   +  +R  + E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187

Query: 166 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 225
            + +V      + + P L ++    K +  W++ D +++V ++CKG KG+ G +V A + 
Sbjct: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247

Query: 226 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 284
            S+I   A+++L     R   K   +K      PSQ RY+ YF+  +      N  P   
Sbjct: 248 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 301

Query: 285 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 341
           LF+   +I  +         Q  ++   ++ S  L   S ++ I      ++ I++    
Sbjct: 302 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 358

Query: 342 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 399
            L  DV V  +            F   F+T  I   +L  P+++LD     +AW  + +P
Sbjct: 359 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 413

Query: 400 PEFAVEILF 408
            + +VE +F
Sbjct: 414 FQASVEFVF 422


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
           [Homo sapiens]
          Length = 1419

 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)

Query: 106 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 165
           +DLDLTYVTERI+A +FP+   +  +R  + E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197

Query: 166 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 225
            + +V      + + P L ++    K +  W++ D +++V ++CKG KG+ G +V A + 
Sbjct: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257

Query: 226 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 284
            S+I   A+++L     R   K   +K      PSQ RY+ YF+  +      N  P   
Sbjct: 258 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 311

Query: 285 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 341
           LF+   +I  +         Q  ++   ++ S  L   S ++ I      ++ I++    
Sbjct: 312 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 368

Query: 342 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 399
            L  DV V  +            F   F+T  I   +L  P+++LD     +AW  + +P
Sbjct: 369 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 423

Query: 400 PEFAVEILF 408
            + +VE +F
Sbjct: 424 FQASVEFVF 432


>gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]
          Length = 461

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%)

Query: 71  IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVT-ERIIAMSFPSSGRQ- 128
           I L+  FH + +  Q   L     + ++  +     + DL ++  +R IA   P S  + 
Sbjct: 140 ITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARL 199

Query: 129 --SFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEM 186
              ++++  E  +++   K+ N   +  L ++R YD K F +       D H++      
Sbjct: 200 ESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAKRFTDAG----FDHHDLFFADGS 252

Query: 187 VVFTKEVNEWM--AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESL 237
                 V E++   ++ E  +A+HCK G GRTGT++ A  I     +TA E++
Sbjct: 253 TPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLI-ACYIMKHYRMTAAETI 304


>gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]
          Length = 459

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%)

Query: 71  IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVT-ERIIAMSFPSSGRQ- 128
           I L+  FH + +  Q   L     + ++  +     + DL ++  +R IA   P S  + 
Sbjct: 177 ITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARL 236

Query: 129 --SFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEM 186
              ++++  E  +++   K+ N   +  L ++R YD K F +       D H++      
Sbjct: 237 ESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAKRFTDAG----FDHHDLFFADGS 289

Query: 187 VVFTKEVNEWM--AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESL 237
                 V E++   ++ E  +A+HCK G GRTGT++ A  I     +TA E++
Sbjct: 290 TPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLI-ACYIMKHYRMTAAETI 341


>gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]
          Length = 498

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%)

Query: 71  IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVT-ERIIAMSFPSSGRQ- 128
           I L+  FH + +  Q   L     + ++  +     + DL ++  +R IA   P S  + 
Sbjct: 177 ITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARL 236

Query: 129 --SFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEM 186
              ++++  E  +++   K+ N   +  L ++R YD K F +       D H++      
Sbjct: 237 ESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAKRFTDAG----FDHHDLFFADGS 289

Query: 187 VVFTKEVNEWM--AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESL 237
                 V E++   ++ E  +A+HCK G GRTGT++ A  I     +TA E++
Sbjct: 290 TPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLI-ACYIMKHYRMTAAETI 341


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 14/121 (11%)

Query: 151  RVYNLCSERAYDP----KHFHNRVSRIMIDDHNVP-TLHEMVVFTKEVNEWMAQDL-ENI 204
            R + +C E   D     +HFH  V      DH VP T   ++ F + V +++ +      
Sbjct: 2062 REFKICGEEQLDAHRLIRHFHYTVW----PDHGVPETTQSLIQFVRTVRDYINRSPGAGP 2117

Query: 205  VAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRY 264
              +HC  G GRTGT +    I  +  L +++S+  +G     + H  +   V+T  Q  Y
Sbjct: 2118 TVVHCSAGVGRTGTFIALDRILQQ--LDSKDSVDIYGAVHDLRLH--RVHMVQTECQYVY 2173

Query: 265  V 265
            +
Sbjct: 2174 L 2174


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 14/121 (11%)

Query: 151  RVYNLCSERAYDP----KHFHNRVSRIMIDDHNVP-TLHEMVVFTKEVNEWMAQDL-ENI 204
            R + +C E   D     +HFH  V      DH VP T   ++ F + V +++ +      
Sbjct: 1844 REFKICGEEQLDAHRLIRHFHYTVW----PDHGVPETTQSLIQFVRTVRDYINRSPGAGP 1899

Query: 205  VAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRY 264
              +HC  G GRTGT +    I  +  L +++S+  +G     + H  +   V+T  Q  Y
Sbjct: 1900 TVVHCSAGVGRTGTFIALDRILQQ--LDSKDSVDIYGAVHDLRLH--RVHMVQTECQYVY 1955

Query: 265  V 265
            +
Sbjct: 1956 L 1956


>gi|205277447 dual specificity phosphatase 11 [Homo sapiens]
          Length = 377

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 157 SERAYDPKHFHNRVS--RIMIDDHNVPTLHEMVVFTKEVNEWMAQDLEN--IVAIHCKGG 212
           ++R Y P+     V   +I    H VP    +  F   VN ++ ++ +N  ++ +HC  G
Sbjct: 143 TQRYYKPEDLPETVPYLKIFTVGHQVPDDETIFKFKHAVNGFLKENKDNDKLIGVHCTHG 202

Query: 213 KGRTGTMVCALLIASE 228
             RTG ++C  LI  E
Sbjct: 203 LNRTGYLICRYLIDVE 218


>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
           2 precursor [Homo sapiens]
          Length = 937

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 2/46 (4%)

Query: 177 DHNVPTLHE-MVVFTKEVNEWMAQDLENIVAI-HCKGGKGRTGTMV 220
           DH VP+  + ++ F + + +W+ Q +E    I HC  G GRTGT++
Sbjct: 808 DHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLI 853


>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
            precursor [Homo sapiens]
          Length = 1115

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 2/46 (4%)

Query: 177  DHNVPTLHE-MVVFTKEVNEWMAQDLENIVAI-HCKGGKGRTGTMV 220
            DH VP+  + ++ F + + +W+ Q +E    I HC  G GRTGT++
Sbjct: 986  DHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLI 1031


>gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
          Length = 383

 Score = 35.8 bits (81), Expect = 0.073
 Identities = 14/38 (36%), Positives = 23/38 (60%)

Query: 197 MAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAE 234
           + ++ E  +A+HCK G GRTGT++   ++    F  AE
Sbjct: 266 ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAE 303


>gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]
          Length = 594

 Score = 35.8 bits (81), Expect = 0.073
 Identities = 14/38 (36%), Positives = 23/38 (60%)

Query: 197 MAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAE 234
           + ++ E  +A+HCK G GRTGT++   ++    F  AE
Sbjct: 266 ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAE 303


>gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
          Length = 623

 Score = 35.8 bits (81), Expect = 0.073
 Identities = 14/38 (36%), Positives = 23/38 (60%)

Query: 197 MAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAE 234
           + ++ E  +A+HCK G GRTGT++   ++    F  AE
Sbjct: 266 ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAE 303


>gi|30089952 protein tyrosine phosphatase domain containing 1
           protein isoform 1 [Homo sapiens]
          Length = 806

 Score = 35.8 bits (81), Expect = 0.073
 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 3/46 (6%)

Query: 202 ENIVAIHCKGGKGRTGTMV-CALLIASEIFLTAEESLYYFGERRTN 246
           E  VAIHC  G GRTG ++ C L+ A+   +TA++++ +   +R N
Sbjct: 235 EGKVAIHCHAGLGRTGVLIACYLVFATR--MTADQAIIFVRAKRPN 278


>gi|30089950 protein tyrosine phosphatase domain containing 1
           protein isoform 2 [Homo sapiens]
          Length = 754

 Score = 35.8 bits (81), Expect = 0.073
 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 3/46 (6%)

Query: 202 ENIVAIHCKGGKGRTGTMV-CALLIASEIFLTAEESLYYFGERRTN 246
           E  VAIHC  G GRTG ++ C L+ A+   +TA++++ +   +R N
Sbjct: 183 EGKVAIHCHAGLGRTGVLIACYLVFATR--MTADQAIIFVRAKRPN 226


>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1
            precursor [Homo sapiens]
          Length = 1337

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 6/73 (8%)

Query: 150  YRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVV-FTKEVNEWMAQDL-ENIVAI 207
            + V N+ +  ++  + FH         DH VP   ++++ F   V ++M Q   E+ + +
Sbjct: 1182 FTVKNIQTSESHPLRQFHFT----SWPDHGVPDTTDLLINFRYLVRDYMKQSPPESPILV 1237

Query: 208  HCKGGKGRTGTMV 220
            HC  G GRTGT +
Sbjct: 1238 HCSAGVGRTGTFI 1250


>gi|148224884 protein tyrosine phosphatase, mitochondrial 1 isoform
           1 [Homo sapiens]
          Length = 201

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 175 IDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 225
           +D   +PTL  +    +   ++  Q L   V +HCK G+ R+ TMV A LI
Sbjct: 100 VDMTGIPTLDNLQKGVQFALKY--QSLGQCVYVHCKAGRSRSATMVAAYLI 148


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,899,937
Number of Sequences: 37866
Number of extensions: 671535
Number of successful extensions: 1538
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 1468
Number of HSP's gapped (non-prelim): 93
length of query: 411
length of database: 18,247,518
effective HSP length: 105
effective length of query: 306
effective length of database: 14,271,588
effective search space: 4367105928
effective search space used: 4367105928
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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