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Search of human proteins with 21389623
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389623 prominin 2 [Homo sapiens]
(834 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389623 prominin 2 [Homo sapiens] 1642 0.0
gi|224994189 prominin 1 isoform 2 [Homo sapiens] 357 3e-98
gi|224994199 prominin 1 isoform 4 [Homo sapiens] 357 3e-98
gi|224994197 prominin 1 isoform 5 [Homo sapiens] 357 3e-98
gi|224994191 prominin 1 isoform 2 [Homo sapiens] 357 3e-98
gi|224994195 prominin 1 isoform 6 [Homo sapiens] 353 3e-97
gi|224994193 prominin 1 isoform 7 [Homo sapiens] 353 3e-97
gi|5174387 prominin 1 isoform 1 [Homo sapiens] 353 3e-97
gi|55770834 centromere protein F [Homo sapiens] 37 0.076
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 37 0.099
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 37 0.099
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 36 0.13
gi|221139761 zinc finger protein 853 [Homo sapiens] 35 0.38
gi|62414289 vimentin [Homo sapiens] 34 0.49
gi|17157993 olfactomedin 2 [Homo sapiens] 34 0.49
gi|58530840 desmoplakin isoform I [Homo sapiens] 34 0.64
gi|21735548 centrosomal protein 2 [Homo sapiens] 34 0.64
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 34 0.64
gi|118498356 kinectin 1 isoform a [Homo sapiens] 33 0.84
gi|118498368 kinectin 1 isoform c [Homo sapiens] 33 0.84
gi|33620775 kinectin 1 isoform a [Homo sapiens] 33 0.84
gi|16262452 cingulin [Homo sapiens] 33 0.84
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 33 0.84
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi... 33 1.1
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi... 33 1.1
gi|4757886 pituitary tumor-transforming gene 1 protein-interacti... 33 1.1
gi|109240552 RUN and FYVE domain-containing 2 isoform b [Homo sa... 33 1.1
gi|222418604 hypothetical protein LOC257407 [Homo sapiens] 33 1.4
gi|105990532 apolipoprotein B precursor [Homo sapiens] 33 1.4
gi|45439359 triple functional domain (PTPRF interacting) [Homo s... 33 1.4
>gi|21389623 prominin 2 [Homo sapiens]
Length = 834
Score = 1642 bits (4251), Expect = 0.0
Identities = 834/834 (100%), Positives = 834/834 (100%)
Query: 1 MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPAARARWLAPRVRAPGLL 60
MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPAARARWLAPRVRAPGLL
Sbjct: 1 MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPAARARWLAPRVRAPGLL 60
Query: 61 DSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVNEVVRYEAGYVVCAVIAGLYLLLV 120
DSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVNEVVRYEAGYVVCAVIAGLYLLLV
Sbjct: 61 DSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVNEVVRYEAGYVVCAVIAGLYLLLV 120
Query: 121 PTAGLCFCCCRCHRRCGGRVKTEHKALACERAALMVFLLLTTLLLLIGVVCAFVTNQRTH 180
PTAGLCFCCCRCHRRCGGRVKTEHKALACERAALMVFLLLTTLLLLIGVVCAFVTNQRTH
Sbjct: 121 PTAGLCFCCCRCHRRCGGRVKTEHKALACERAALMVFLLLTTLLLLIGVVCAFVTNQRTH 180
Query: 181 EQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSAIHTQ 240
EQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSAIHTQ
Sbjct: 181 EQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSAIHTQ 240
Query: 241 LRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLELLQE 300
LRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLELLQE
Sbjct: 241 LRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLELLQE 300
Query: 301 ARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA 360
ARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA
Sbjct: 301 ARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA 360
Query: 361 LAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQR 420
LAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQR
Sbjct: 361 LAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQR 420
Query: 421 YETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEAGARFLMAGVGL 480
YETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEAGARFLMAGVGL
Sbjct: 421 YETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEAGARFLMAGVGL 480
Query: 481 SFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSMNLSQLLGLRKN 540
SFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSMNLSQLLGLRKN
Sbjct: 481 SFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSMNLSQLLGLRKN 540
Query: 541 ISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSS 600
ISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSS
Sbjct: 541 ISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSS 600
Query: 601 AARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQE 660
AARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQE
Sbjct: 601 AARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQE 660
Query: 661 EAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGELPAWAA 720
EAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGELPAWAA
Sbjct: 661 EAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGELPAWAA 720
Query: 721 RILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNA 780
RILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNA
Sbjct: 721 RILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNA 780
Query: 781 FWFCLAWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL 834
FWFCLAWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL
Sbjct: 781 FWFCLAWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL 834
>gi|224994189 prominin 1 isoform 2 [Homo sapiens]
Length = 856
Score = 357 bits (916), Expect = 3e-98
Identities = 205/763 (26%), Positives = 387/763 (50%), Gaps = 14/763 (1%)
Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN--EVVRYEAGYVVCAVIAGL 115
G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG ++C V+ L
Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLL 109
Query: 116 YLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLLLIGVVCAFV 174
+++L+P G FC CRC +CGG + K R + LL+ +++ IG+ FV
Sbjct: 110 FIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFV 169
Query: 175 TNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIG 234
N + ++ S + L L+++ P++++ + Q++ +++ +L+ + +G
Sbjct: 170 ANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLG 229
Query: 235 SAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRL 294
I +LR ++ P+L + S+ ++ + L+ +N+T+ L L ++ + L
Sbjct: 230 GGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSL 289
Query: 295 LELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQ 349
L + C C L + Q+P VD L + V + +VQ
Sbjct: 290 RSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQ 349
Query: 350 EENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEE 409
+ + N +P QT++VV +K+ + + + + P + S ++ + E
Sbjct: 350 QGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTES 409
Query: 410 SSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEA 469
L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P+
Sbjct: 410 YIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNT 469
Query: 470 GARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSM 529
G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF DTP L
Sbjct: 470 GGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDW 529
Query: 530 NL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQEL 585
+L K ++ Q Y CK+ + L L +S+++ EHL+IN++T + EL
Sbjct: 530 EYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSEL 589
Query: 586 QSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGL 645
+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ A +L+
Sbjct: 590 ESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAK 648
Query: 646 AQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705
A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + L + +L
Sbjct: 649 ANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRIL 708
Query: 706 ANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDN 765
A++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C+P++ ALD
Sbjct: 709 ASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDT 768
Query: 766 S-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807
+ V LC + DP N FWF + T FL+P++IFAVK +KY+R
Sbjct: 769 AVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 811
>gi|224994199 prominin 1 isoform 4 [Homo sapiens]
Length = 825
Score = 357 bits (916), Expect = 3e-98
Identities = 205/763 (26%), Positives = 387/763 (50%), Gaps = 14/763 (1%)
Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN--EVVRYEAGYVVCAVIAGL 115
G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG ++C V+ L
Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLL 109
Query: 116 YLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLLLIGVVCAFV 174
+++L+P G FC CRC +CGG + K R + LL+ +++ IG+ FV
Sbjct: 110 FIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFV 169
Query: 175 TNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIG 234
N + ++ S + L L+++ P++++ + Q++ +++ +L+ + +G
Sbjct: 170 ANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLG 229
Query: 235 SAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRL 294
I +LR ++ P+L + S+ ++ + L+ +N+T+ L L ++ + L
Sbjct: 230 GGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSL 289
Query: 295 LELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQ 349
L + C C L + Q+P VD L + V + +VQ
Sbjct: 290 RSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQ 349
Query: 350 EENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEE 409
+ + N +P QT++VV +K+ + + + + P + S ++ + E
Sbjct: 350 QGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTES 409
Query: 410 SSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEA 469
L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P+
Sbjct: 410 YIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNT 469
Query: 470 GARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSM 529
G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF DTP L
Sbjct: 470 GGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDW 529
Query: 530 NL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQEL 585
+L K ++ Q Y CK+ + L L +S+++ EHL+IN++T + EL
Sbjct: 530 EYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSEL 589
Query: 586 QSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGL 645
+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ A +L+
Sbjct: 590 ESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAK 648
Query: 646 AQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705
A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + L + +L
Sbjct: 649 ANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRIL 708
Query: 706 ANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDN 765
A++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C+P++ ALD
Sbjct: 709 ASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDT 768
Query: 766 S-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807
+ V LC + DP N FWF + T FL+P++IFAVK +KY+R
Sbjct: 769 AVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 811
>gi|224994197 prominin 1 isoform 5 [Homo sapiens]
Length = 833
Score = 357 bits (916), Expect = 3e-98
Identities = 205/763 (26%), Positives = 387/763 (50%), Gaps = 14/763 (1%)
Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN--EVVRYEAGYVVCAVIAGL 115
G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG ++C V+ L
Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLL 109
Query: 116 YLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLLLIGVVCAFV 174
+++L+P G FC CRC +CGG + K R + LL+ +++ IG+ FV
Sbjct: 110 FIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFV 169
Query: 175 TNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIG 234
N + ++ S + L L+++ P++++ + Q++ +++ +L+ + +G
Sbjct: 170 ANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLG 229
Query: 235 SAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRL 294
I +LR ++ P+L + S+ ++ + L+ +N+T+ L L ++ + L
Sbjct: 230 GGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSL 289
Query: 295 LELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQ 349
L + C C L + Q+P VD L + V + +VQ
Sbjct: 290 RSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQ 349
Query: 350 EENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEE 409
+ + N +P QT++VV +K+ + + + + P + S ++ + E
Sbjct: 350 QGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTES 409
Query: 410 SSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEA 469
L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P+
Sbjct: 410 YIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNT 469
Query: 470 GARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSM 529
G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF DTP L
Sbjct: 470 GGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDW 529
Query: 530 NL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQEL 585
+L K ++ Q Y CK+ + L L +S+++ EHL+IN++T + EL
Sbjct: 530 EYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSEL 589
Query: 586 QSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGL 645
+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ A +L+
Sbjct: 590 ESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAK 648
Query: 646 AQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705
A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + L + +L
Sbjct: 649 ANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRIL 708
Query: 706 ANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDN 765
A++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C+P++ ALD
Sbjct: 709 ASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDT 768
Query: 766 S-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807
+ V LC + DP N FWF + T FL+P++IFAVK +KY+R
Sbjct: 769 AVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 811
>gi|224994191 prominin 1 isoform 2 [Homo sapiens]
Length = 856
Score = 357 bits (916), Expect = 3e-98
Identities = 205/763 (26%), Positives = 387/763 (50%), Gaps = 14/763 (1%)
Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN--EVVRYEAGYVVCAVIAGL 115
G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG ++C V+ L
Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLL 109
Query: 116 YLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLLLIGVVCAFV 174
+++L+P G FC CRC +CGG + K R + LL+ +++ IG+ FV
Sbjct: 110 FIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFV 169
Query: 175 TNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIG 234
N + ++ S + L L+++ P++++ + Q++ +++ +L+ + +G
Sbjct: 170 ANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLG 229
Query: 235 SAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRL 294
I +LR ++ P+L + S+ ++ + L+ +N+T+ L L ++ + L
Sbjct: 230 GGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSL 289
Query: 295 LELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQ 349
L + C C L + Q+P VD L + V + +VQ
Sbjct: 290 RSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQ 349
Query: 350 EENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEE 409
+ + N +P QT++VV +K+ + + + + P + S ++ + E
Sbjct: 350 QGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTES 409
Query: 410 SSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEA 469
L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P+
Sbjct: 410 YIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNT 469
Query: 470 GARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSM 529
G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF DTP L
Sbjct: 470 GGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDW 529
Query: 530 NL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQEL 585
+L K ++ Q Y CK+ + L L +S+++ EHL+IN++T + EL
Sbjct: 530 EYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSEL 589
Query: 586 QSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGL 645
+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ A +L+
Sbjct: 590 ESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAK 648
Query: 646 AQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705
A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + L + +L
Sbjct: 649 ANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRIL 708
Query: 706 ANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDN 765
A++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C+P++ ALD
Sbjct: 709 ASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDT 768
Query: 766 S-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807
+ V LC + DP N FWF + T FL+P++IFAVK +KY+R
Sbjct: 769 AVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 811
>gi|224994195 prominin 1 isoform 6 [Homo sapiens]
Length = 834
Score = 353 bits (907), Expect = 3e-97
Identities = 205/772 (26%), Positives = 387/772 (50%), Gaps = 23/772 (2%)
Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN-----------EVVRYEAGY 106
G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG
Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGLKIVYYEAGI 109
Query: 107 VVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLL 165
++C V+ L+++L+P G FC CRC +CGG + K R + LL+ +++
Sbjct: 110 ILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIII 169
Query: 166 LIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEE 225
IG+ FV N + ++ S + L L+++ P++++ + Q++ +++ +
Sbjct: 170 SIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTD 229
Query: 226 LDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEP 285
L+ + +G I +LR ++ P+L + S+ ++ + L+ +N+T+ L L
Sbjct: 230 LNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSS 289
Query: 286 AIREHRDRLLELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVP 340
++ + L L + C C L + Q+P VD L + V
Sbjct: 290 SLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVL 349
Query: 341 EANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRW 400
+ +VQ+ + N +P QT++VV +K+ + + + + P + S +
Sbjct: 350 RTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAF 409
Query: 401 AQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDP 460
+ + E L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P
Sbjct: 410 SVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATP 469
Query: 461 SHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFAD 520
+ G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF D
Sbjct: 470 TTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLD 529
Query: 521 TPGNLPPSMNL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQ 576
TP L +L K ++ Q Y CK+ + L L +S+++ EHL+IN+
Sbjct: 530 TPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINE 589
Query: 577 YTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSME 636
+T + EL+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++
Sbjct: 590 HTGSISSELESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLL 648
Query: 637 QLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPN 696
A +L+ A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ +
Sbjct: 649 SFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNG 708
Query: 697 LQLETSDVLANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATC 756
L + +LA++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C
Sbjct: 709 LLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASC 768
Query: 757 QPLSGALDNS-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807
+P++ ALD + V LC + DP N FWF + T FL+P++IFAVK +KY+R
Sbjct: 769 KPVATALDTAVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 820
>gi|224994193 prominin 1 isoform 7 [Homo sapiens]
Length = 842
Score = 353 bits (907), Expect = 3e-97
Identities = 205/772 (26%), Positives = 387/772 (50%), Gaps = 23/772 (2%)
Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN-----------EVVRYEAGY 106
G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG
Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGLKIVYYEAGI 109
Query: 107 VVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLL 165
++C V+ L+++L+P G FC CRC +CGG + K R + LL+ +++
Sbjct: 110 ILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIII 169
Query: 166 LIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEE 225
IG+ FV N + ++ S + L L+++ P++++ + Q++ +++ +
Sbjct: 170 SIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTD 229
Query: 226 LDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEP 285
L+ + +G I +LR ++ P+L + S+ ++ + L+ +N+T+ L L
Sbjct: 230 LNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSS 289
Query: 286 AIREHRDRLLELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVP 340
++ + L L + C C L + Q+P VD L + V
Sbjct: 290 SLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVL 349
Query: 341 EANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRW 400
+ +VQ+ + N +P QT++VV +K+ + + + + P + S +
Sbjct: 350 RTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAF 409
Query: 401 AQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDP 460
+ + E L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P
Sbjct: 410 SVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATP 469
Query: 461 SHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFAD 520
+ G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF D
Sbjct: 470 TTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLD 529
Query: 521 TPGNLPPSMNL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQ 576
TP L +L K ++ Q Y CK+ + L L +S+++ EHL+IN+
Sbjct: 530 TPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINE 589
Query: 577 YTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSME 636
+T + EL+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++
Sbjct: 590 HTGSISSELESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLL 648
Query: 637 QLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPN 696
A +L+ A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ +
Sbjct: 649 SFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNG 708
Query: 697 LQLETSDVLANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATC 756
L + +LA++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C
Sbjct: 709 LLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASC 768
Query: 757 QPLSGALDNS-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807
+P++ ALD + V LC + DP N FWF + T FL+P++IFAVK +KY+R
Sbjct: 769 KPVATALDTAVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 820
>gi|5174387 prominin 1 isoform 1 [Homo sapiens]
Length = 865
Score = 353 bits (907), Expect = 3e-97
Identities = 205/772 (26%), Positives = 387/772 (50%), Gaps = 23/772 (2%)
Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN-----------EVVRYEAGY 106
G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG
Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGLKIVYYEAGI 109
Query: 107 VVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLL 165
++C V+ L+++L+P G FC CRC +CGG + K R + LL+ +++
Sbjct: 110 ILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIII 169
Query: 166 LIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEE 225
IG+ FV N + ++ S + L L+++ P++++ + Q++ +++ +
Sbjct: 170 SIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTD 229
Query: 226 LDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEP 285
L+ + +G I +LR ++ P+L + S+ ++ + L+ +N+T+ L L
Sbjct: 230 LNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSS 289
Query: 286 AIREHRDRLLELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVP 340
++ + L L + C C L + Q+P VD L + V
Sbjct: 290 SLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVL 349
Query: 341 EANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRW 400
+ +VQ+ + N +P QT++VV +K+ + + + + P + S +
Sbjct: 350 RTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAF 409
Query: 401 AQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDP 460
+ + E L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P
Sbjct: 410 SVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATP 469
Query: 461 SHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFAD 520
+ G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF D
Sbjct: 470 TTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLD 529
Query: 521 TPGNLPPSMNL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQ 576
TP L +L K ++ Q Y CK+ + L L +S+++ EHL+IN+
Sbjct: 530 TPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINE 589
Query: 577 YTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSME 636
+T + EL+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++
Sbjct: 590 HTGSISSELESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLL 648
Query: 637 QLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPN 696
A +L+ A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ +
Sbjct: 649 SFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNG 708
Query: 697 LQLETSDVLANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATC 756
L + +LA++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C
Sbjct: 709 LLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASC 768
Query: 757 QPLSGALDNS-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807
+P++ ALD + V LC + DP N FWF + T FL+P++IFAVK +KY+R
Sbjct: 769 KPVATALDTAVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 820
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 37.0 bits (84), Expect = 0.076
Identities = 41/158 (25%), Positives = 69/158 (43%), Gaps = 15/158 (9%)
Query: 568 LEEHLDI-NQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQI 626
LEE L + N+LR EL ++ T +LD LS + + L+S + +H +Q+
Sbjct: 1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLH----CIQV 2004
Query: 627 QRPVVKTSMEQLAQELQGLAQ-AQDNSVLGQRLQ-----EEAQGLRNLHQEKVVPQ---- 676
VK E L +++ +D + L ++LQ +A L E + Q
Sbjct: 2005 AEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE 2064
Query: 677 QSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGE 714
+ L+ K + S++A S + +L S L KGE
Sbjct: 2065 KELLVKESESLQARLSESDYEKLNVSKALEAALVEKGE 2102
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 36.6 bits (83), Expect = 0.099
Identities = 52/200 (26%), Positives = 88/200 (44%), Gaps = 31/200 (15%)
Query: 531 LSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEE-HLDI---NQYTNKLRQELQ 586
L++ R+NI A +Q ++ L+T+L S L E LD+ +Q +K+++ Q
Sbjct: 5293 LTEATNHRQNIE-KMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQ 5351
Query: 587 SLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLA 646
S K +Q L +DL + + + D +VQ KT + L +EL G
Sbjct: 5352 S-KATSQELSRQIQKLAKDLTTILTKLKAKT---DNVVQ-----AKTDQKVLGEELDGCN 5402
Query: 647 QA------------QDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSA 694
+ N LG+ L ++ L LHQ+ + ++ ++KLN + LE
Sbjct: 5403 SKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYN 5462
Query: 695 PNLQL-----ETSDVLANVT 709
L+L E + VLA+ T
Sbjct: 5463 EMLELILKWIEKAKVLAHGT 5482
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 36.6 bits (83), Expect = 0.099
Identities = 52/200 (26%), Positives = 88/200 (44%), Gaps = 31/200 (15%)
Query: 531 LSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEE-HLDI---NQYTNKLRQELQ 586
L++ R+NI A +Q ++ L+T+L S L E LD+ +Q +K+++ Q
Sbjct: 5364 LTEATNHRQNIE-KMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQ 5422
Query: 587 SLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLA 646
S K +Q L +DL + + + D +VQ KT + L +EL G
Sbjct: 5423 S-KATSQELSRQIQKLAKDLTTILTKLKAKT---DNVVQ-----AKTDQKVLGEELDGCN 5473
Query: 647 QA------------QDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSA 694
+ N LG+ L ++ L LHQ+ + ++ ++KLN + LE
Sbjct: 5474 SKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYN 5533
Query: 695 PNLQL-----ETSDVLANVT 709
L+L E + VLA+ T
Sbjct: 5534 EMLELILKWIEKAKVLAHGT 5553
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 36.2 bits (82), Expect = 0.13
Identities = 52/179 (29%), Positives = 76/179 (42%), Gaps = 19/179 (10%)
Query: 250 AAVGSLGQVLQVSVHHLQT-LNATVVELQAGQQD---LEPAIREHRDRLLELLQEARCQG 305
A + Q LQ HL+ L +LQA QD L RE +RLLEL + A G
Sbjct: 456 AGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWG 515
Query: 306 DCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANF---SSMVQEENSTFNALPALA 362
+ A AR L + ++ L Q + + E S V+ N AL
Sbjct: 516 EQAE----ARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQ 571
Query: 363 AMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRY 421
+ Q V +EL K + + E + L E +E S+ AQ+LQ+ + YL +Q+Y
Sbjct: 572 SEQ--HVKRELGKKLGELQEKLSELKE---TVELKSQEAQSLQQQRDQ---YLGHLQQY 622
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 34.7 bits (78), Expect = 0.38
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 531 LSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLR-QELQSLK 589
LSQL K+ S+H +Q+ K L Q ++E + Q +L+ Q+ Q +
Sbjct: 130 LSQLQQ-EKHQSVH--HQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQ 186
Query: 590 VDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQ 649
V Q L + L Q LQ+ Q+Q+ + EQL Q+ Q L Q
Sbjct: 187 VLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQ 246
Query: 650 DNSVLGQRLQEEAQGLRN--LHQEKVVPQQSLV 680
+ Q LQ++ L+ L Q++ QQ L+
Sbjct: 247 QGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLL 279
Score = 30.4 bits (67), Expect = 7.1
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 7/121 (5%)
Query: 562 LNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPD 621
L L++ + Q + +++LQ ++ Q L ++ E LQ Q++
Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQ--QQLLLLQ 245
Query: 622 FLVQIQRPVVKTSMEQLAQEL--QGLAQAQDNSVLGQR---LQEEAQGLRNLHQEKVVPQ 676
Q+Q+ +++ QL Q+L Q AQ Q +L Q+ Q++ Q L QE++ Q
Sbjct: 246 QQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQ 305
Query: 677 Q 677
Q
Sbjct: 306 Q 306
>gi|62414289 vimentin [Homo sapiens]
Length = 466
Score = 34.3 bits (77), Expect = 0.49
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 16/144 (11%)
Query: 561 QLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYP 620
+L D Y+ EE ++ + ++L + ++V+ D L+ R E LQ LQR
Sbjct: 145 RLGDLYE-EEMRELRRQVDQLTNDKARVEVER---DNLAEDIMRLREKLQEEMLQREEAE 200
Query: 621 DFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLV 680
+ L ++ V S+ +L E + + LQEE L+ LH+E++ Q+ +
Sbjct: 201 NTLQSFRQDVDNASLARLDLERK-----------VESLQEEIAFLKKLHEEEIQELQAQI 249
Query: 681 AKLNLSVRALESSAPNLQLETSDV 704
+ ++ + ++ S P+L DV
Sbjct: 250 QEQHVQI-DVDVSKPDLTAALRDV 272
>gi|17157993 olfactomedin 2 [Homo sapiens]
Length = 454
Score = 34.3 bits (77), Expect = 0.49
Identities = 57/247 (23%), Positives = 96/247 (38%), Gaps = 50/247 (20%)
Query: 522 PGNLPPSMNLSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYT--- 578
P +PP + LL L ++ +Q +EG L+T Q D + + Q T
Sbjct: 3 PLTVPPPL----LLLLCSGLAGQTLFQNPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSR 58
Query: 579 ----NKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTS 634
+LRQ ++ ++ +QS+++L RDL+ ++
Sbjct: 59 DGRSRELRQLMEKVQNVSQSMEVLELRTYRDLQYVR-----------------------G 95
Query: 635 MEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQ-----SLVAKLNLSVRA 689
ME L + L +A D S+ + QE + L V +Q + +L VR
Sbjct: 96 METLMRSLDARLRAADGSLSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRN 155
Query: 690 LESSAPNLQLET-----SDVLANVTYLKGELPAWAARI----LRNVSECFLAREMGYFSQ 740
L S +Q E D+ V L+ L A A ++ L VS R MG S+
Sbjct: 156 LSGSLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITVRAMG--SR 213
Query: 741 YVAWVRE 747
+ +W+ +
Sbjct: 214 FGSWMTD 220
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 33.9 bits (76), Expect = 0.64
Identities = 33/144 (22%), Positives = 71/144 (49%), Gaps = 19/144 (13%)
Query: 566 YDLEE-HLDINQYTNKLR---QELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPD 621
YDL++ + + NKL+ QEL L++D + + + +D+ Q+S +
Sbjct: 1512 YDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKE------ 1565
Query: 622 FLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVA 681
+Q+Q+ V+ + +L + A ++S ++L+EE +G+R +E+ + +L
Sbjct: 1566 --LQLQKQKVEEELNRLKRT------ASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQ 1617
Query: 682 KLNLSVRALESSAPNLQLETSDVL 705
+L + + S +L+ + DVL
Sbjct: 1618 QLEQASIVKKRSEDDLR-QQRDVL 1640
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 33.9 bits (76), Expect = 0.64
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 7/163 (4%)
Query: 267 QTLNATVVELQAGQQDLEPAIREHRDRLLELLQEA----RCQGDCAGALSWARTLELGAD 322
+T +LQ Q++L+ A R+HRD L L +E+ + + D + ++ + D
Sbjct: 964 ETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQD 1023
Query: 323 FSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPE 382
SQ V +L+ E N E L + Q V+QE Q+
Sbjct: 1024 DSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELS 1083
Query: 383 GVRTLAEGFPG--LEAASRWAQALQEVEESSRPYL-QEVQRYE 422
+R + G E +++ QEV+E +L QE Q E
Sbjct: 1084 ALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLE 1126
Score = 31.2 bits (69), Expect = 4.2
Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Query: 569 EEHL-DINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQ 627
+EH+ ++ + ++L Q+LQ L LL S +++ LQ LQ L +
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQ-LQEAREQGELKE-- 1798
Query: 628 RPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSV 687
++ QL + + LAQ Q+ Q++AQG +EK Q + + ++++
Sbjct: 1799 ----QSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTL 1854
Query: 688 R 688
+
Sbjct: 1855 K 1855
Score = 30.8 bits (68), Expect = 5.4
Identities = 37/139 (26%), Positives = 58/139 (41%), Gaps = 21/139 (15%)
Query: 177 QRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSA 236
Q+T + + ++ + E L S V ELQ + +Q S QE+ S+
Sbjct: 1256 QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSK---------WEG 1306
Query: 237 IHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLE 296
L S + L + SL L+ + LQ + A G+++L A +E+ +E
Sbjct: 1307 KQNSLESELMELHETMASLQSRLRRA--ELQRMEA------QGERELLQAAKENLTAQVE 1358
Query: 297 LLQ----EARCQGDCAGAL 311
LQ EAR Q AG L
Sbjct: 1359 HLQAAVVEARAQASAAGIL 1377
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 33.9 bits (76), Expect = 0.64
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 27/128 (21%)
Query: 548 QQCKEGAALWTVLQLNDSYDLE--EHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRD 605
QQC T+ L S D E +++ + K+ ++L +++ LS A R+
Sbjct: 1602 QQC-------TIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQ------LSCANRQV 1648
Query: 606 LEALQSSGLQRIHYPDFLVQI------------QRPVVKTSMEQLAQELQGLAQAQDNSV 653
EA +S G +I D +Q+ Q V + L EL+ L Q+ +
Sbjct: 1649 SEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTE 1708
Query: 654 LGQRLQEE 661
G+RL EE
Sbjct: 1709 RGRRLSEE 1716
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 33.5 bits (75), Expect = 0.84
Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 18/171 (10%)
Query: 267 QTLNATVVELQAGQQDLEPAIREHRDRLLELLQEARC-QGDCAGALSWARTLE--LGADF 323
+ L ++++ +++L AIR L + +Q+ + Q D S L+ +
Sbjct: 749 ELLETGLIQVATKEEELN-AIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD 807
Query: 324 SQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA---------LAAMQTSSVVQELK 374
++ SV+ +L + + + AN VQ+ AL + +S VQEL+
Sbjct: 808 GKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866
Query: 375 KAVAQQPEGVRT----LAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRY 421
+ + E + T L E L +W Q LQE ES + ++QEV ++
Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917
Score = 30.8 bits (68), Expect = 5.4
Identities = 41/200 (20%), Positives = 78/200 (39%), Gaps = 36/200 (18%)
Query: 572 LDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIH--YPDFLVQI--- 626
+ Q ++ E+ LK + L S LE+ QS+ L ++ Y + ++
Sbjct: 406 MKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 627 -----QRPVVKTSMEQLAQELQGLAQAQDN------SVLGQRLQEEAQGLRNLHQEKVVP 675
Q V K + EQ A +L+ Q + S + +R E ++L + V
Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525
Query: 676 QQ-----------SLVAKLNLSVRALE---------SSAPNLQLETSDVLANVTYLKGEL 715
+ +LV+K L R ++ + +LQ++ D+L LK ++
Sbjct: 526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585
Query: 716 PAWAARILRNVSECFLAREM 735
+ ++I S LA E+
Sbjct: 586 QQFHSQIAAQTSASVLAEEL 605
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 33.5 bits (75), Expect = 0.84
Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 18/171 (10%)
Query: 267 QTLNATVVELQAGQQDLEPAIREHRDRLLELLQEARC-QGDCAGALSWARTLE--LGADF 323
+ L ++++ +++L AIR L + +Q+ + Q D S L+ +
Sbjct: 749 ELLETGLIQVATKEEELN-AIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD 807
Query: 324 SQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA---------LAAMQTSSVVQELK 374
++ SV+ +L + + + AN VQ+ AL + +S VQEL+
Sbjct: 808 GKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866
Query: 375 KAVAQQPEGVRT----LAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRY 421
+ + E + T L E L +W Q LQE ES + ++QEV ++
Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917
Score = 30.8 bits (68), Expect = 5.4
Identities = 41/200 (20%), Positives = 78/200 (39%), Gaps = 36/200 (18%)
Query: 572 LDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIH--YPDFLVQI--- 626
+ Q ++ E+ LK + L S LE+ QS+ L ++ Y + ++
Sbjct: 406 MKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 627 -----QRPVVKTSMEQLAQELQGLAQAQDN------SVLGQRLQEEAQGLRNLHQEKVVP 675
Q V K + EQ A +L+ Q + S + +R E ++L + V
Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525
Query: 676 QQ-----------SLVAKLNLSVRALE---------SSAPNLQLETSDVLANVTYLKGEL 715
+ +LV+K L R ++ + +LQ++ D+L LK ++
Sbjct: 526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585
Query: 716 PAWAARILRNVSECFLAREM 735
+ ++I S LA E+
Sbjct: 586 QQFHSQIAAQTSASVLAEEL 605
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 33.5 bits (75), Expect = 0.84
Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 18/171 (10%)
Query: 267 QTLNATVVELQAGQQDLEPAIREHRDRLLELLQEARC-QGDCAGALSWARTLE--LGADF 323
+ L ++++ +++L AIR L + +Q+ + Q D S L+ +
Sbjct: 749 ELLETGLIQVATKEEELN-AIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD 807
Query: 324 SQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA---------LAAMQTSSVVQELK 374
++ SV+ +L + + + AN VQ+ AL + +S VQEL+
Sbjct: 808 GKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866
Query: 375 KAVAQQPEGVRT----LAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRY 421
+ + E + T L E L +W Q LQE ES + ++QEV ++
Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917
Score = 30.8 bits (68), Expect = 5.4
Identities = 41/200 (20%), Positives = 78/200 (39%), Gaps = 36/200 (18%)
Query: 572 LDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIH--YPDFLVQI--- 626
+ Q ++ E+ LK + L S LE+ QS+ L ++ Y + ++
Sbjct: 406 MKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 627 -----QRPVVKTSMEQLAQELQGLAQAQDN------SVLGQRLQEEAQGLRNLHQEKVVP 675
Q V K + EQ A +L+ Q + S + +R E ++L + V
Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525
Query: 676 QQ-----------SLVAKLNLSVRALE---------SSAPNLQLETSDVLANVTYLKGEL 715
+ +LV+K L R ++ + +LQ++ D+L LK ++
Sbjct: 526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585
Query: 716 PAWAARILRNVSECFLAREM 735
+ ++I S LA E+
Sbjct: 586 QQFHSQIAAQTSASVLAEEL 605
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 33.5 bits (75), Expect = 0.84
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 8/102 (7%)
Query: 574 INQYTNKLRQELQSLKVDTQSLDLLSSAARRD--LEALQSSGLQRIHYPDFLVQIQRPVV 631
+ Y K R+E+ + Q+ D S A + L LQ +QR+ Q +R
Sbjct: 876 LEDYKEKARREVADAQ--RQAKDWASEAEKTSGGLSRLQDE-IQRLRQALQASQAERDTA 932
Query: 632 KTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKV 673
+ E LAQ LQGL Q +N Q + A+ L+ L +EKV
Sbjct: 933 RLDKELLAQRLQGLEQEAENKKRSQ--DDRARQLKGL-EEKV 971
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 33.5 bits (75), Expect = 0.84
Identities = 67/242 (27%), Positives = 99/242 (40%), Gaps = 36/242 (14%)
Query: 558 TVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVD------------------TQSLDLLS 599
+VL+L++S LEE ++ + +L++ELQSL QS+ LL+
Sbjct: 618 SVLRLSNSNLLEELGELGRERQRLQRELQSLSQRLQREFVPKPEAQVQLQQLRQSVGLLT 677
Query: 600 SAAR---------RDLEALQSSGLQRIH--YPDFLVQIQRPVVKT--SMEQLAQELQGLA 646
+ R L A QSSGL+ + P LV + K S+E+L + L
Sbjct: 678 NELAMEKEATEKLRKLLASQSSGLRGLWDCLPADLVGERSAQSKAAESLEELRACISTLV 737
Query: 647 -QAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705
+ ++ + RLQEE Q LR P SL A + V ALE L+ E V
Sbjct: 738 DRHREAQQVLARLQEENQQLRGSLSPCREPGTSLKAPASPQVAALEQDLGKLEEELRAVQ 797
Query: 706 ANVTYLK---GELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGA 762
A ++ G+L + V+E ARE Q+ V Q A Q L
Sbjct: 798 ATMSGKSQEIGKLKQLLYQATEEVAE-LRAREAASLRQHEKTRGSLVAQAQAWGQELKAL 856
Query: 763 LD 764
L+
Sbjct: 857 LE 858
>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
sapiens]
Length = 562
Score = 33.1 bits (74), Expect = 1.1
Identities = 25/101 (24%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 234 GSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDR 293
G ++ L+ + + A +L Q+ ++ + + A +++ + AI EHRD+
Sbjct: 235 GDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDK 294
Query: 294 LLELLQEARCQGDCAGALSWARTLELGADF-SQVPSVDHVL 333
LL+ L++ R Q + + L A+ +L AD + V +H+L
Sbjct: 295 LLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLL 335
>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
sapiens]
Length = 580
Score = 33.1 bits (74), Expect = 1.1
Identities = 25/101 (24%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 234 GSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDR 293
G ++ L+ + + A +L Q+ ++ + + A +++ + AI EHRD+
Sbjct: 235 GDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDK 294
Query: 294 LLELLQEARCQGDCAGALSWARTLELGADF-SQVPSVDHVL 333
LL+ L++ R Q + + L A+ +L AD + V +H+L
Sbjct: 295 LLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLL 335
>gi|4757886 pituitary tumor-transforming gene 1 protein-interacting
protein precursor [Homo sapiens]
Length = 180
Score = 33.1 bits (74), Expect = 1.1
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 8/73 (10%)
Query: 78 PFPSELVKALLNELASVKVNEV-VRYEAGYVVCAVIAGLYLLLVPTAGLCFCCCRCHRRC 136
P S L A L +L+S + V +EA + +V+ G LL G+ CCC C RR
Sbjct: 70 PVTSVLPPASLCKLSSARWGVCWVNFEALIITMSVVGGTLLL-----GIAICCCCCCRRK 124
Query: 137 GGRV--KTEHKAL 147
R ++E KA+
Sbjct: 125 RSRKPDRSEEKAM 137
>gi|109240552 RUN and FYVE domain-containing 2 isoform b [Homo
sapiens]
Length = 403
Score = 33.1 bits (74), Expect = 1.1
Identities = 36/149 (24%), Positives = 69/149 (46%), Gaps = 18/149 (12%)
Query: 569 EEHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQI-Q 627
++HL++ + + ELQ+ K Q LD + + ARR L S L++ + VQ+
Sbjct: 236 QQHLEVTKVD--VETELQTYKHSRQGLDEMYNEARRQLR--DESQLRQDVENELAVQVSM 291
Query: 628 RPVVKTSMEQLAQELQ-------GLAQAQD-----NSVLGQRLQEEAQGLRNLHQEKVVP 675
+ ++ +M+ L +++ GL Q + N + Q+LQ GL+ E +
Sbjct: 292 KHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKE-KNEIIAR 350
Query: 676 QQSLVAKLNLSVRALESSAPNLQLETSDV 704
+ K+ ++R LE S +L +T +
Sbjct: 351 LEEKTNKITAAMRQLEQSDNDLLTQTRTI 379
>gi|222418604 hypothetical protein LOC257407 [Homo sapiens]
Length = 295
Score = 32.7 bits (73), Expect = 1.4
Identities = 32/115 (27%), Positives = 46/115 (40%), Gaps = 1/115 (0%)
Query: 286 AIREHRDRLLELLQEARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFS 345
A RE R RL E+L++ R + AL E G + + P + + L+ V
Sbjct: 117 AAREPRRRLREMLRDVRGRRRAGAALVGVLVAEAGPEDAVAPGLRLLEALLRAVFGRQAG 176
Query: 346 SMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRW 400
VQ + LPA ++ + L+ A A QP G PGL A W
Sbjct: 177 GPVQAA-AYCPGLPASCLAVQAAACRALQAAGAGQPVEGAWERPGLPGLLACFSW 230
>gi|105990532 apolipoprotein B precursor [Homo sapiens]
Length = 4563
Score = 32.7 bits (73), Expect = 1.4
Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 450 GIWGLSARDDPSHPEAKGEAGARF----LMAGVGLSFLFAAPLILLVFATFLVGGNVQTL 505
G +GLS + DP+ GE+ RF L ++ + + L + L G ++
Sbjct: 1499 GTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQSGIIKNT 1558
Query: 506 VCRSWENGELFEFADTPGNLP--PSMNLSQLLGLRKNISIHQAYQQCKEGAALWTVLQLN 563
+EN EL +DT G + N + ++N + YQ E +++L +
Sbjct: 1559 ASLKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGS 1618
Query: 564 -DSYDLEEHLDI 574
+S+ LE + DI
Sbjct: 1619 LNSHGLELNADI 1630
>gi|45439359 triple functional domain (PTPRF interacting) [Homo
sapiens]
Length = 3097
Score = 32.7 bits (73), Expect = 1.4
Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 22/163 (13%)
Query: 276 LQAGQQDLEPAIREHRDRLLELLQEARCQGDCAGALSWARTLE--LGADFSQVPSVDHVL 333
L QQ+L+ A +HR L + +Q Q + L W R E L A S+
Sbjct: 885 LHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEA- 943
Query: 334 HQLKGVPEANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPG 393
QL+ E F +++ + +A+Q + + +A + +R AE
Sbjct: 944 EQLQREHE-QFQHAIEKTHQ--------SALQVQQKAEAMLQANHYDMDMIRDCAE---- 990
Query: 394 LEAASRWAQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVV 436
+ AS W Q + ++E+ + V Y+T + CSV+
Sbjct: 991 -KVASHWQQLMLKMEDRLKLVNASVAFYKTSEQV-----CSVL 1027
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,507,001
Number of Sequences: 37866
Number of extensions: 1249520
Number of successful extensions: 4485
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 4350
Number of HSP's gapped (non-prelim): 161
length of query: 834
length of database: 18,247,518
effective HSP length: 111
effective length of query: 723
effective length of database: 14,044,392
effective search space: 10154095416
effective search space used: 10154095416
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.