BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21389623 prominin 2 [Homo sapiens] (834 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21389623 prominin 2 [Homo sapiens] 1642 0.0 gi|224994189 prominin 1 isoform 2 [Homo sapiens] 357 3e-98 gi|224994199 prominin 1 isoform 4 [Homo sapiens] 357 3e-98 gi|224994197 prominin 1 isoform 5 [Homo sapiens] 357 3e-98 gi|224994191 prominin 1 isoform 2 [Homo sapiens] 357 3e-98 gi|224994195 prominin 1 isoform 6 [Homo sapiens] 353 3e-97 gi|224994193 prominin 1 isoform 7 [Homo sapiens] 353 3e-97 gi|5174387 prominin 1 isoform 1 [Homo sapiens] 353 3e-97 gi|55770834 centromere protein F [Homo sapiens] 37 0.076 gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 37 0.099 gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 37 0.099 gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 36 0.13 gi|221139761 zinc finger protein 853 [Homo sapiens] 35 0.38 gi|62414289 vimentin [Homo sapiens] 34 0.49 gi|17157993 olfactomedin 2 [Homo sapiens] 34 0.49 gi|58530840 desmoplakin isoform I [Homo sapiens] 34 0.64 gi|21735548 centrosomal protein 2 [Homo sapiens] 34 0.64 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 34 0.64 gi|118498356 kinectin 1 isoform a [Homo sapiens] 33 0.84 gi|118498368 kinectin 1 isoform c [Homo sapiens] 33 0.84 gi|33620775 kinectin 1 isoform a [Homo sapiens] 33 0.84 gi|16262452 cingulin [Homo sapiens] 33 0.84 gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 33 0.84 gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi... 33 1.1 gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi... 33 1.1 gi|4757886 pituitary tumor-transforming gene 1 protein-interacti... 33 1.1 gi|109240552 RUN and FYVE domain-containing 2 isoform b [Homo sa... 33 1.1 gi|222418604 hypothetical protein LOC257407 [Homo sapiens] 33 1.4 gi|105990532 apolipoprotein B precursor [Homo sapiens] 33 1.4 gi|45439359 triple functional domain (PTPRF interacting) [Homo s... 33 1.4 >gi|21389623 prominin 2 [Homo sapiens] Length = 834 Score = 1642 bits (4251), Expect = 0.0 Identities = 834/834 (100%), Positives = 834/834 (100%) Query: 1 MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPAARARWLAPRVRAPGLL 60 MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPAARARWLAPRVRAPGLL Sbjct: 1 MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPAARARWLAPRVRAPGLL 60 Query: 61 DSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVNEVVRYEAGYVVCAVIAGLYLLLV 120 DSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVNEVVRYEAGYVVCAVIAGLYLLLV Sbjct: 61 DSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVNEVVRYEAGYVVCAVIAGLYLLLV 120 Query: 121 PTAGLCFCCCRCHRRCGGRVKTEHKALACERAALMVFLLLTTLLLLIGVVCAFVTNQRTH 180 PTAGLCFCCCRCHRRCGGRVKTEHKALACERAALMVFLLLTTLLLLIGVVCAFVTNQRTH Sbjct: 121 PTAGLCFCCCRCHRRCGGRVKTEHKALACERAALMVFLLLTTLLLLIGVVCAFVTNQRTH 180 Query: 181 EQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSAIHTQ 240 EQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSAIHTQ Sbjct: 181 EQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSAIHTQ 240 Query: 241 LRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLELLQE 300 LRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLELLQE Sbjct: 241 LRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLELLQE 300 Query: 301 ARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA 360 ARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA Sbjct: 301 ARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA 360 Query: 361 LAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQR 420 LAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQR Sbjct: 361 LAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQR 420 Query: 421 YETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEAGARFLMAGVGL 480 YETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEAGARFLMAGVGL Sbjct: 421 YETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEAGARFLMAGVGL 480 Query: 481 SFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSMNLSQLLGLRKN 540 SFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSMNLSQLLGLRKN Sbjct: 481 SFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSMNLSQLLGLRKN 540 Query: 541 ISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSS 600 ISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSS Sbjct: 541 ISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSS 600 Query: 601 AARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQE 660 AARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQE Sbjct: 601 AARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQE 660 Query: 661 EAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGELPAWAA 720 EAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGELPAWAA Sbjct: 661 EAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGELPAWAA 720 Query: 721 RILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNA 780 RILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNA Sbjct: 721 RILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNA 780 Query: 781 FWFCLAWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL 834 FWFCLAWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL Sbjct: 781 FWFCLAWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL 834 >gi|224994189 prominin 1 isoform 2 [Homo sapiens] Length = 856 Score = 357 bits (916), Expect = 3e-98 Identities = 205/763 (26%), Positives = 387/763 (50%), Gaps = 14/763 (1%) Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN--EVVRYEAGYVVCAVIAGL 115 G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG ++C V+ L Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLL 109 Query: 116 YLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLLLIGVVCAFV 174 +++L+P G FC CRC +CGG + K R + LL+ +++ IG+ FV Sbjct: 110 FIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFV 169 Query: 175 TNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIG 234 N + ++ S + L L+++ P++++ + Q++ +++ +L+ + +G Sbjct: 170 ANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLG 229 Query: 235 SAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRL 294 I +LR ++ P+L + S+ ++ + L+ +N+T+ L L ++ + L Sbjct: 230 GGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSL 289 Query: 295 LELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQ 349 L + C C L + Q+P VD L + V + +VQ Sbjct: 290 RSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQ 349 Query: 350 EENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEE 409 + + N +P QT++VV +K+ + + + + P + S ++ + E Sbjct: 350 QGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTES 409 Query: 410 SSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEA 469 L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P+ Sbjct: 410 YIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNT 469 Query: 470 GARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSM 529 G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF DTP L Sbjct: 470 GGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDW 529 Query: 530 NL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQEL 585 +L K ++ Q Y CK+ + L L +S+++ EHL+IN++T + EL Sbjct: 530 EYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSEL 589 Query: 586 QSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGL 645 +SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ A +L+ Sbjct: 590 ESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAK 648 Query: 646 AQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705 A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + L + +L Sbjct: 649 ANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRIL 708 Query: 706 ANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDN 765 A++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C+P++ ALD Sbjct: 709 ASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDT 768 Query: 766 S-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807 + V LC + DP N FWF + T FL+P++IFAVK +KY+R Sbjct: 769 AVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 811 >gi|224994199 prominin 1 isoform 4 [Homo sapiens] Length = 825 Score = 357 bits (916), Expect = 3e-98 Identities = 205/763 (26%), Positives = 387/763 (50%), Gaps = 14/763 (1%) Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN--EVVRYEAGYVVCAVIAGL 115 G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG ++C V+ L Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLL 109 Query: 116 YLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLLLIGVVCAFV 174 +++L+P G FC CRC +CGG + K R + LL+ +++ IG+ FV Sbjct: 110 FIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFV 169 Query: 175 TNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIG 234 N + ++ S + L L+++ P++++ + Q++ +++ +L+ + +G Sbjct: 170 ANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLG 229 Query: 235 SAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRL 294 I +LR ++ P+L + S+ ++ + L+ +N+T+ L L ++ + L Sbjct: 230 GGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSL 289 Query: 295 LELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQ 349 L + C C L + Q+P VD L + V + +VQ Sbjct: 290 RSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQ 349 Query: 350 EENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEE 409 + + N +P QT++VV +K+ + + + + P + S ++ + E Sbjct: 350 QGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTES 409 Query: 410 SSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEA 469 L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P+ Sbjct: 410 YIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNT 469 Query: 470 GARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSM 529 G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF DTP L Sbjct: 470 GGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDW 529 Query: 530 NL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQEL 585 +L K ++ Q Y CK+ + L L +S+++ EHL+IN++T + EL Sbjct: 530 EYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSEL 589 Query: 586 QSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGL 645 +SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ A +L+ Sbjct: 590 ESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAK 648 Query: 646 AQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705 A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + L + +L Sbjct: 649 ANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRIL 708 Query: 706 ANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDN 765 A++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C+P++ ALD Sbjct: 709 ASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDT 768 Query: 766 S-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807 + V LC + DP N FWF + T FL+P++IFAVK +KY+R Sbjct: 769 AVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 811 >gi|224994197 prominin 1 isoform 5 [Homo sapiens] Length = 833 Score = 357 bits (916), Expect = 3e-98 Identities = 205/763 (26%), Positives = 387/763 (50%), Gaps = 14/763 (1%) Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN--EVVRYEAGYVVCAVIAGL 115 G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG ++C V+ L Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLL 109 Query: 116 YLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLLLIGVVCAFV 174 +++L+P G FC CRC +CGG + K R + LL+ +++ IG+ FV Sbjct: 110 FIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFV 169 Query: 175 TNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIG 234 N + ++ S + L L+++ P++++ + Q++ +++ +L+ + +G Sbjct: 170 ANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLG 229 Query: 235 SAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRL 294 I +LR ++ P+L + S+ ++ + L+ +N+T+ L L ++ + L Sbjct: 230 GGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSL 289 Query: 295 LELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQ 349 L + C C L + Q+P VD L + V + +VQ Sbjct: 290 RSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQ 349 Query: 350 EENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEE 409 + + N +P QT++VV +K+ + + + + P + S ++ + E Sbjct: 350 QGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTES 409 Query: 410 SSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEA 469 L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P+ Sbjct: 410 YIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNT 469 Query: 470 GARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSM 529 G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF DTP L Sbjct: 470 GGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDW 529 Query: 530 NL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQEL 585 +L K ++ Q Y CK+ + L L +S+++ EHL+IN++T + EL Sbjct: 530 EYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSEL 589 Query: 586 QSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGL 645 +SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ A +L+ Sbjct: 590 ESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAK 648 Query: 646 AQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705 A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + L + +L Sbjct: 649 ANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRIL 708 Query: 706 ANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDN 765 A++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C+P++ ALD Sbjct: 709 ASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDT 768 Query: 766 S-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807 + V LC + DP N FWF + T FL+P++IFAVK +KY+R Sbjct: 769 AVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 811 >gi|224994191 prominin 1 isoform 2 [Homo sapiens] Length = 856 Score = 357 bits (916), Expect = 3e-98 Identities = 205/763 (26%), Positives = 387/763 (50%), Gaps = 14/763 (1%) Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN--EVVRYEAGYVVCAVIAGL 115 G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG ++C V+ L Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIILCCVLGLL 109 Query: 116 YLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLLLIGVVCAFV 174 +++L+P G FC CRC +CGG + K R + LL+ +++ IG+ FV Sbjct: 110 FIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFV 169 Query: 175 TNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIG 234 N + ++ S + L L+++ P++++ + Q++ +++ +L+ + +G Sbjct: 170 ANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLG 229 Query: 235 SAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRL 294 I +LR ++ P+L + S+ ++ + L+ +N+T+ L L ++ + L Sbjct: 230 GGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSL 289 Query: 295 LELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQ 349 L + C C L + Q+P VD L + V + +VQ Sbjct: 290 RSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQ 349 Query: 350 EENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEE 409 + + N +P QT++VV +K+ + + + + P + S ++ + E Sbjct: 350 QGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAFSVYVNNTES 409 Query: 410 SSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEA 469 L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P+ Sbjct: 410 YIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNT 469 Query: 470 GARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSM 529 G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF DTP L Sbjct: 470 GGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDW 529 Query: 530 NL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQEL 585 +L K ++ Q Y CK+ + L L +S+++ EHL+IN++T + EL Sbjct: 530 EYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSEL 589 Query: 586 QSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGL 645 +SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ A +L+ Sbjct: 590 ESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAK 648 Query: 646 AQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705 A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + L + +L Sbjct: 649 ANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRIL 708 Query: 706 ANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDN 765 A++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C+P++ ALD Sbjct: 709 ASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDT 768 Query: 766 S-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807 + V LC + DP N FWF + T FL+P++IFAVK +KY+R Sbjct: 769 AVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 811 >gi|224994195 prominin 1 isoform 6 [Homo sapiens] Length = 834 Score = 353 bits (907), Expect = 3e-97 Identities = 205/772 (26%), Positives = 387/772 (50%), Gaps = 23/772 (2%) Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN-----------EVVRYEAGY 106 G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGLKIVYYEAGI 109 Query: 107 VVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLL 165 ++C V+ L+++L+P G FC CRC +CGG + K R + LL+ +++ Sbjct: 110 ILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIII 169 Query: 166 LIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEE 225 IG+ FV N + ++ S + L L+++ P++++ + Q++ +++ + Sbjct: 170 SIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTD 229 Query: 226 LDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEP 285 L+ + +G I +LR ++ P+L + S+ ++ + L+ +N+T+ L L Sbjct: 230 LNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSS 289 Query: 286 AIREHRDRLLELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVP 340 ++ + L L + C C L + Q+P VD L + V Sbjct: 290 SLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVL 349 Query: 341 EANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRW 400 + +VQ+ + N +P QT++VV +K+ + + + + P + S + Sbjct: 350 RTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAF 409 Query: 401 AQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDP 460 + + E L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P Sbjct: 410 SVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATP 469 Query: 461 SHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFAD 520 + G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF D Sbjct: 470 TTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLD 529 Query: 521 TPGNLPPSMNL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQ 576 TP L +L K ++ Q Y CK+ + L L +S+++ EHL+IN+ Sbjct: 530 TPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINE 589 Query: 577 YTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSME 636 +T + EL+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ Sbjct: 590 HTGSISSELESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLL 648 Query: 637 QLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPN 696 A +L+ A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + Sbjct: 649 SFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNG 708 Query: 697 LQLETSDVLANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATC 756 L + +LA++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C Sbjct: 709 LLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASC 768 Query: 757 QPLSGALDNS-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807 +P++ ALD + V LC + DP N FWF + T FL+P++IFAVK +KY+R Sbjct: 769 KPVATALDTAVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 820 >gi|224994193 prominin 1 isoform 7 [Homo sapiens] Length = 842 Score = 353 bits (907), Expect = 3e-97 Identities = 205/772 (26%), Positives = 387/772 (50%), Gaps = 23/772 (2%) Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN-----------EVVRYEAGY 106 G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGLKIVYYEAGI 109 Query: 107 VVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLL 165 ++C V+ L+++L+P G FC CRC +CGG + K R + LL+ +++ Sbjct: 110 ILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIII 169 Query: 166 LIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEE 225 IG+ FV N + ++ S + L L+++ P++++ + Q++ +++ + Sbjct: 170 SIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTD 229 Query: 226 LDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEP 285 L+ + +G I +LR ++ P+L + S+ ++ + L+ +N+T+ L L Sbjct: 230 LNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSS 289 Query: 286 AIREHRDRLLELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVP 340 ++ + L L + C C L + Q+P VD L + V Sbjct: 290 SLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVL 349 Query: 341 EANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRW 400 + +VQ+ + N +P QT++VV +K+ + + + + P + S + Sbjct: 350 RTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAF 409 Query: 401 AQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDP 460 + + E L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P Sbjct: 410 SVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATP 469 Query: 461 SHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFAD 520 + G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF D Sbjct: 470 TTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLD 529 Query: 521 TPGNLPPSMNL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQ 576 TP L +L K ++ Q Y CK+ + L L +S+++ EHL+IN+ Sbjct: 530 TPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINE 589 Query: 577 YTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSME 636 +T + EL+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ Sbjct: 590 HTGSISSELESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLL 648 Query: 637 QLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPN 696 A +L+ A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + Sbjct: 649 SFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNG 708 Query: 697 LQLETSDVLANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATC 756 L + +LA++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C Sbjct: 709 LLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASC 768 Query: 757 QPLSGALDNS-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807 +P++ ALD + V LC + DP N FWF + T FL+P++IFAVK +KY+R Sbjct: 769 KPVATALDTAVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 820 >gi|5174387 prominin 1 isoform 1 [Homo sapiens] Length = 865 Score = 353 bits (907), Expect = 3e-97 Identities = 205/772 (26%), Positives = 387/772 (50%), Gaps = 23/772 (2%) Query: 58 GLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVN-----------EVVRYEAGY 106 G + L+ V FL VVQ FP + ++ L + K++ ++V YEAG Sbjct: 50 GPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGLKIVYYEAGI 109 Query: 107 VVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALA-CERAALMVFLLLTTLLL 165 ++C V+ L+++L+P G FC CRC +CGG + K R + LL+ +++ Sbjct: 110 ILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIII 169 Query: 166 LIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEE 225 IG+ FV N + ++ S + L L+++ P++++ + Q++ +++ + Sbjct: 170 SIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTD 229 Query: 226 LDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEP 285 L+ + +G I +LR ++ P+L + S+ ++ + L+ +N+T+ L L Sbjct: 230 LNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSS 289 Query: 286 AIREHRDRLLELLQEARC-----QGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVP 340 ++ + L L + C C L + Q+P VD L + V Sbjct: 290 SLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVL 349 Query: 341 EANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRW 400 + +VQ+ + N +P QT++VV +K+ + + + + P + S + Sbjct: 350 RTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLPIQDILSAF 409 Query: 401 AQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDP 460 + + E L ++ Y++Y W+ G V+CS++ +V+ LGL G+ G P Sbjct: 410 SVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATP 469 Query: 461 SHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCRSWENGELFEFAD 520 + G FLM GVGLSFLF L+++V TF+ G NV+ L+C + + ELF D Sbjct: 470 TTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLD 529 Query: 521 TPGNLPPSMNL---SQLLGLRK-NISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQ 576 TP L +L K ++ Q Y CK+ + L L +S+++ EHL+IN+ Sbjct: 530 TPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINE 589 Query: 577 YTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSME 636 +T + EL+SLKV+ ++ LL +A R++L+ + G+ R++Y +L Q + ++ Sbjct: 590 HTGSISSELESLKVNL-NIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLL 648 Query: 637 QLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPN 696 A +L+ A + L L+ +AQ ++ +HQ++V+P + ++ L SV+ L+ + Sbjct: 649 SFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTGNG 708 Query: 697 LQLETSDVLANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATC 756 L + +LA++ + + + + ++ ++ + +GYF Y+ W+ +++++A+C Sbjct: 709 LLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASC 768 Query: 757 QPLSGALDNS-RVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFR 807 +P++ ALD + V LC + DP N FWF + T FL+P++IFAVK +KY+R Sbjct: 769 KPVATALDTAVDVFLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYR 820 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 37.0 bits (84), Expect = 0.076 Identities = 41/158 (25%), Positives = 69/158 (43%), Gaps = 15/158 (9%) Query: 568 LEEHLDI-NQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQI 626 LEE L + N+LR EL ++ T +LD LS + + L+S + +H +Q+ Sbjct: 1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLH----CIQV 2004 Query: 627 QRPVVKTSMEQLAQELQGLAQ-AQDNSVLGQRLQ-----EEAQGLRNLHQEKVVPQ---- 676 VK E L +++ +D + L ++LQ +A L E + Q Sbjct: 2005 AEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE 2064 Query: 677 QSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGE 714 + L+ K + S++A S + +L S L KGE Sbjct: 2065 KELLVKESESLQARLSESDYEKLNVSKALEAALVEKGE 2102 >gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2 [Homo sapiens] Length = 8749 Score = 36.6 bits (83), Expect = 0.099 Identities = 52/200 (26%), Positives = 88/200 (44%), Gaps = 31/200 (15%) Query: 531 LSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEE-HLDI---NQYTNKLRQELQ 586 L++ R+NI A +Q ++ L+T+L S L E LD+ +Q +K+++ Q Sbjct: 5293 LTEATNHRQNIE-KMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQ 5351 Query: 587 SLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLA 646 S K +Q L +DL + + + D +VQ KT + L +EL G Sbjct: 5352 S-KATSQELSRQIQKLAKDLTTILTKLKAKT---DNVVQ-----AKTDQKVLGEELDGCN 5402 Query: 647 QA------------QDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSA 694 + N LG+ L ++ L LHQ+ + ++ ++KLN + LE Sbjct: 5403 SKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYN 5462 Query: 695 PNLQL-----ETSDVLANVT 709 L+L E + VLA+ T Sbjct: 5463 EMLELILKWIEKAKVLAHGT 5482 >gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1 [Homo sapiens] Length = 8797 Score = 36.6 bits (83), Expect = 0.099 Identities = 52/200 (26%), Positives = 88/200 (44%), Gaps = 31/200 (15%) Query: 531 LSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEE-HLDI---NQYTNKLRQELQ 586 L++ R+NI A +Q ++ L+T+L S L E LD+ +Q +K+++ Q Sbjct: 5364 LTEATNHRQNIE-KMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQ 5422 Query: 587 SLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLA 646 S K +Q L +DL + + + D +VQ KT + L +EL G Sbjct: 5423 S-KATSQELSRQIQKLAKDLTTILTKLKAKT---DNVVQ-----AKTDQKVLGEELDGCN 5473 Query: 647 QA------------QDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSA 694 + N LG+ L ++ L LHQ+ + ++ ++KLN + LE Sbjct: 5474 SKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYN 5533 Query: 695 PNLQL-----ETSDVLANVT 709 L+L E + VLA+ T Sbjct: 5534 EMLELILKWIEKAKVLAHGT 5553 >gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapiens] Length = 1002 Score = 36.2 bits (82), Expect = 0.13 Identities = 52/179 (29%), Positives = 76/179 (42%), Gaps = 19/179 (10%) Query: 250 AAVGSLGQVLQVSVHHLQT-LNATVVELQAGQQD---LEPAIREHRDRLLELLQEARCQG 305 A + Q LQ HL+ L +LQA QD L RE +RLLEL + A G Sbjct: 456 AGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWG 515 Query: 306 DCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANF---SSMVQEENSTFNALPALA 362 + A AR L + ++ L Q + + E S V+ N AL Sbjct: 516 EQAE----ARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQ 571 Query: 363 AMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRY 421 + Q V +EL K + + E + L E +E S+ AQ+LQ+ + YL +Q+Y Sbjct: 572 SEQ--HVKRELGKKLGELQEKLSELKE---TVELKSQEAQSLQQQRDQ---YLGHLQQY 622 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 34.7 bits (78), Expect = 0.38 Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 6/153 (3%) Query: 531 LSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLR-QELQSLK 589 LSQL K+ S+H +Q+ K L Q ++E + Q +L+ Q+ Q + Sbjct: 130 LSQLQQ-EKHQSVH--HQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQ 186 Query: 590 VDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQ 649 V Q L + L Q LQ+ Q+Q+ + EQL Q+ Q L Q Sbjct: 187 VLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQ 246 Query: 650 DNSVLGQRLQEEAQGLRN--LHQEKVVPQQSLV 680 + Q LQ++ L+ L Q++ QQ L+ Sbjct: 247 QGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLL 279 Score = 30.4 bits (67), Expect = 7.1 Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 7/121 (5%) Query: 562 LNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPD 621 L L++ + Q + +++LQ ++ Q L ++ E LQ Q++ Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQ--QQLLLLQ 245 Query: 622 FLVQIQRPVVKTSMEQLAQEL--QGLAQAQDNSVLGQR---LQEEAQGLRNLHQEKVVPQ 676 Q+Q+ +++ QL Q+L Q AQ Q +L Q+ Q++ Q L QE++ Q Sbjct: 246 QQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQ 305 Query: 677 Q 677 Q Sbjct: 306 Q 306 >gi|62414289 vimentin [Homo sapiens] Length = 466 Score = 34.3 bits (77), Expect = 0.49 Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 16/144 (11%) Query: 561 QLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYP 620 +L D Y+ EE ++ + ++L + ++V+ D L+ R E LQ LQR Sbjct: 145 RLGDLYE-EEMRELRRQVDQLTNDKARVEVER---DNLAEDIMRLREKLQEEMLQREEAE 200 Query: 621 DFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLV 680 + L ++ V S+ +L E + + LQEE L+ LH+E++ Q+ + Sbjct: 201 NTLQSFRQDVDNASLARLDLERK-----------VESLQEEIAFLKKLHEEEIQELQAQI 249 Query: 681 AKLNLSVRALESSAPNLQLETSDV 704 + ++ + ++ S P+L DV Sbjct: 250 QEQHVQI-DVDVSKPDLTAALRDV 272 >gi|17157993 olfactomedin 2 [Homo sapiens] Length = 454 Score = 34.3 bits (77), Expect = 0.49 Identities = 57/247 (23%), Positives = 96/247 (38%), Gaps = 50/247 (20%) Query: 522 PGNLPPSMNLSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYT--- 578 P +PP + LL L ++ +Q +EG L+T Q D + + Q T Sbjct: 3 PLTVPPPL----LLLLCSGLAGQTLFQNPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSR 58 Query: 579 ----NKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTS 634 +LRQ ++ ++ +QS+++L RDL+ ++ Sbjct: 59 DGRSRELRQLMEKVQNVSQSMEVLELRTYRDLQYVR-----------------------G 95 Query: 635 MEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQ-----SLVAKLNLSVRA 689 ME L + L +A D S+ + QE + L V +Q + +L VR Sbjct: 96 METLMRSLDARLRAADGSLSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRN 155 Query: 690 LESSAPNLQLET-----SDVLANVTYLKGELPAWAARI----LRNVSECFLAREMGYFSQ 740 L S +Q E D+ V L+ L A A ++ L VS R MG S+ Sbjct: 156 LSGSLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITVRAMG--SR 213 Query: 741 YVAWVRE 747 + +W+ + Sbjct: 214 FGSWMTD 220 >gi|58530840 desmoplakin isoform I [Homo sapiens] Length = 2871 Score = 33.9 bits (76), Expect = 0.64 Identities = 33/144 (22%), Positives = 71/144 (49%), Gaps = 19/144 (13%) Query: 566 YDLEE-HLDINQYTNKLR---QELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPD 621 YDL++ + + NKL+ QEL L++D + + + +D+ Q+S + Sbjct: 1512 YDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKE------ 1565 Query: 622 FLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVA 681 +Q+Q+ V+ + +L + A ++S ++L+EE +G+R +E+ + +L Sbjct: 1566 --LQLQKQKVEEELNRLKRT------ASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQ 1617 Query: 682 KLNLSVRALESSAPNLQLETSDVL 705 +L + + S +L+ + DVL Sbjct: 1618 QLEQASIVKKRSEDDLR-QQRDVL 1640 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 33.9 bits (76), Expect = 0.64 Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 7/163 (4%) Query: 267 QTLNATVVELQAGQQDLEPAIREHRDRLLELLQEA----RCQGDCAGALSWARTLELGAD 322 +T +LQ Q++L+ A R+HRD L L +E+ + + D + ++ + D Sbjct: 964 ETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQD 1023 Query: 323 FSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPE 382 SQ V +L+ E N E L + Q V+QE Q+ Sbjct: 1024 DSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELS 1083 Query: 383 GVRTLAEGFPG--LEAASRWAQALQEVEESSRPYL-QEVQRYE 422 +R + G E +++ QEV+E +L QE Q E Sbjct: 1084 ALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLE 1126 Score = 31.2 bits (69), Expect = 4.2 Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 8/121 (6%) Query: 569 EEHL-DINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQ 627 +EH+ ++ + ++L Q+LQ L LL S +++ LQ LQ L + Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQ-LQEAREQGELKE-- 1798 Query: 628 RPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSV 687 ++ QL + + LAQ Q+ Q++AQG +EK Q + + ++++ Sbjct: 1799 ----QSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTL 1854 Query: 688 R 688 + Sbjct: 1855 K 1855 Score = 30.8 bits (68), Expect = 5.4 Identities = 37/139 (26%), Positives = 58/139 (41%), Gaps = 21/139 (15%) Query: 177 QRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSA 236 Q+T + + ++ + E L S V ELQ + +Q S QE+ S+ Sbjct: 1256 QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSK---------WEG 1306 Query: 237 IHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLE 296 L S + L + SL L+ + LQ + A G+++L A +E+ +E Sbjct: 1307 KQNSLESELMELHETMASLQSRLRRA--ELQRMEA------QGERELLQAAKENLTAQVE 1358 Query: 297 LLQ----EARCQGDCAGAL 311 LQ EAR Q AG L Sbjct: 1359 HLQAAVVEARAQASAAGIL 1377 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 33.9 bits (76), Expect = 0.64 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 27/128 (21%) Query: 548 QQCKEGAALWTVLQLNDSYDLE--EHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRD 605 QQC T+ L S D E +++ + K+ ++L +++ LS A R+ Sbjct: 1602 QQC-------TIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQ------LSCANRQV 1648 Query: 606 LEALQSSGLQRIHYPDFLVQI------------QRPVVKTSMEQLAQELQGLAQAQDNSV 653 EA +S G +I D +Q+ Q V + L EL+ L Q+ + Sbjct: 1649 SEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTE 1708 Query: 654 LGQRLQEE 661 G+RL EE Sbjct: 1709 RGRRLSEE 1716 >gi|118498356 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 33.5 bits (75), Expect = 0.84 Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 18/171 (10%) Query: 267 QTLNATVVELQAGQQDLEPAIREHRDRLLELLQEARC-QGDCAGALSWARTLE--LGADF 323 + L ++++ +++L AIR L + +Q+ + Q D S L+ + Sbjct: 749 ELLETGLIQVATKEEELN-AIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD 807 Query: 324 SQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA---------LAAMQTSSVVQELK 374 ++ SV+ +L + + + AN VQ+ AL + +S VQEL+ Sbjct: 808 GKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866 Query: 375 KAVAQQPEGVRT----LAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRY 421 + + E + T L E L +W Q LQE ES + ++QEV ++ Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917 Score = 30.8 bits (68), Expect = 5.4 Identities = 41/200 (20%), Positives = 78/200 (39%), Gaps = 36/200 (18%) Query: 572 LDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIH--YPDFLVQI--- 626 + Q ++ E+ LK + L S LE+ QS+ L ++ Y + ++ Sbjct: 406 MKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465 Query: 627 -----QRPVVKTSMEQLAQELQGLAQAQDN------SVLGQRLQEEAQGLRNLHQEKVVP 675 Q V K + EQ A +L+ Q + S + +R E ++L + V Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525 Query: 676 QQ-----------SLVAKLNLSVRALE---------SSAPNLQLETSDVLANVTYLKGEL 715 + +LV+K L R ++ + +LQ++ D+L LK ++ Sbjct: 526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585 Query: 716 PAWAARILRNVSECFLAREM 735 + ++I S LA E+ Sbjct: 586 QQFHSQIAAQTSASVLAEEL 605 >gi|118498368 kinectin 1 isoform c [Homo sapiens] Length = 1300 Score = 33.5 bits (75), Expect = 0.84 Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 18/171 (10%) Query: 267 QTLNATVVELQAGQQDLEPAIREHRDRLLELLQEARC-QGDCAGALSWARTLE--LGADF 323 + L ++++ +++L AIR L + +Q+ + Q D S L+ + Sbjct: 749 ELLETGLIQVATKEEELN-AIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD 807 Query: 324 SQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA---------LAAMQTSSVVQELK 374 ++ SV+ +L + + + AN VQ+ AL + +S VQEL+ Sbjct: 808 GKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866 Query: 375 KAVAQQPEGVRT----LAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRY 421 + + E + T L E L +W Q LQE ES + ++QEV ++ Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917 Score = 30.8 bits (68), Expect = 5.4 Identities = 41/200 (20%), Positives = 78/200 (39%), Gaps = 36/200 (18%) Query: 572 LDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIH--YPDFLVQI--- 626 + Q ++ E+ LK + L S LE+ QS+ L ++ Y + ++ Sbjct: 406 MKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465 Query: 627 -----QRPVVKTSMEQLAQELQGLAQAQDN------SVLGQRLQEEAQGLRNLHQEKVVP 675 Q V K + EQ A +L+ Q + S + +R E ++L + V Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525 Query: 676 QQ-----------SLVAKLNLSVRALE---------SSAPNLQLETSDVLANVTYLKGEL 715 + +LV+K L R ++ + +LQ++ D+L LK ++ Sbjct: 526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585 Query: 716 PAWAARILRNVSECFLAREM 735 + ++I S LA E+ Sbjct: 586 QQFHSQIAAQTSASVLAEEL 605 >gi|33620775 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 33.5 bits (75), Expect = 0.84 Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 18/171 (10%) Query: 267 QTLNATVVELQAGQQDLEPAIREHRDRLLELLQEARC-QGDCAGALSWARTLE--LGADF 323 + L ++++ +++L AIR L + +Q+ + Q D S L+ + Sbjct: 749 ELLETGLIQVATKEEELN-AIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD 807 Query: 324 SQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPA---------LAAMQTSSVVQELK 374 ++ SV+ +L + + + AN VQ+ AL + +S VQEL+ Sbjct: 808 GKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866 Query: 375 KAVAQQPEGVRT----LAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRY 421 + + E + T L E L +W Q LQE ES + ++QEV ++ Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917 Score = 30.8 bits (68), Expect = 5.4 Identities = 41/200 (20%), Positives = 78/200 (39%), Gaps = 36/200 (18%) Query: 572 LDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIH--YPDFLVQI--- 626 + Q ++ E+ LK + L S LE+ QS+ L ++ Y + ++ Sbjct: 406 MKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465 Query: 627 -----QRPVVKTSMEQLAQELQGLAQAQDN------SVLGQRLQEEAQGLRNLHQEKVVP 675 Q V K + EQ A +L+ Q + S + +R E ++L + V Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525 Query: 676 QQ-----------SLVAKLNLSVRALE---------SSAPNLQLETSDVLANVTYLKGEL 715 + +LV+K L R ++ + +LQ++ D+L LK ++ Sbjct: 526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585 Query: 716 PAWAARILRNVSECFLAREM 735 + ++I S LA E+ Sbjct: 586 QQFHSQIAAQTSASVLAEEL 605 >gi|16262452 cingulin [Homo sapiens] Length = 1203 Score = 33.5 bits (75), Expect = 0.84 Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 8/102 (7%) Query: 574 INQYTNKLRQELQSLKVDTQSLDLLSSAARRD--LEALQSSGLQRIHYPDFLVQIQRPVV 631 + Y K R+E+ + Q+ D S A + L LQ +QR+ Q +R Sbjct: 876 LEDYKEKARREVADAQ--RQAKDWASEAEKTSGGLSRLQDE-IQRLRQALQASQAERDTA 932 Query: 632 KTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKV 673 + E LAQ LQGL Q +N Q + A+ L+ L +EKV Sbjct: 933 RLDKELLAQRLQGLEQEAENKKRSQ--DDRARQLKGL-EEKV 971 >gi|121582655 ankyrin repeat domain 35 [Homo sapiens] Length = 1001 Score = 33.5 bits (75), Expect = 0.84 Identities = 67/242 (27%), Positives = 99/242 (40%), Gaps = 36/242 (14%) Query: 558 TVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVD------------------TQSLDLLS 599 +VL+L++S LEE ++ + +L++ELQSL QS+ LL+ Sbjct: 618 SVLRLSNSNLLEELGELGRERQRLQRELQSLSQRLQREFVPKPEAQVQLQQLRQSVGLLT 677 Query: 600 SAAR---------RDLEALQSSGLQRIH--YPDFLVQIQRPVVKT--SMEQLAQELQGLA 646 + R L A QSSGL+ + P LV + K S+E+L + L Sbjct: 678 NELAMEKEATEKLRKLLASQSSGLRGLWDCLPADLVGERSAQSKAAESLEELRACISTLV 737 Query: 647 -QAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVL 705 + ++ + RLQEE Q LR P SL A + V ALE L+ E V Sbjct: 738 DRHREAQQVLARLQEENQQLRGSLSPCREPGTSLKAPASPQVAALEQDLGKLEEELRAVQ 797 Query: 706 ANVTYLK---GELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGA 762 A ++ G+L + V+E ARE Q+ V Q A Q L Sbjct: 798 ATMSGKSQEIGKLKQLLYQATEEVAE-LRAREAASLRQHEKTRGSLVAQAQAWGQELKAL 856 Query: 763 LD 764 L+ Sbjct: 857 LE 858 >gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapiens] Length = 562 Score = 33.1 bits (74), Expect = 1.1 Identities = 25/101 (24%), Positives = 51/101 (50%), Gaps = 1/101 (0%) Query: 234 GSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDR 293 G ++ L+ + + A +L Q+ ++ + + A +++ + AI EHRD+ Sbjct: 235 GDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDK 294 Query: 294 LLELLQEARCQGDCAGALSWARTLELGADF-SQVPSVDHVL 333 LL+ L++ R Q + + L A+ +L AD + V +H+L Sbjct: 295 LLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLL 335 >gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapiens] Length = 580 Score = 33.1 bits (74), Expect = 1.1 Identities = 25/101 (24%), Positives = 51/101 (50%), Gaps = 1/101 (0%) Query: 234 GSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDR 293 G ++ L+ + + A +L Q+ ++ + + A +++ + AI EHRD+ Sbjct: 235 GDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDK 294 Query: 294 LLELLQEARCQGDCAGALSWARTLELGADF-SQVPSVDHVL 333 LL+ L++ R Q + + L A+ +L AD + V +H+L Sbjct: 295 LLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLL 335 >gi|4757886 pituitary tumor-transforming gene 1 protein-interacting protein precursor [Homo sapiens] Length = 180 Score = 33.1 bits (74), Expect = 1.1 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 8/73 (10%) Query: 78 PFPSELVKALLNELASVKVNEV-VRYEAGYVVCAVIAGLYLLLVPTAGLCFCCCRCHRRC 136 P S L A L +L+S + V +EA + +V+ G LL G+ CCC C RR Sbjct: 70 PVTSVLPPASLCKLSSARWGVCWVNFEALIITMSVVGGTLLL-----GIAICCCCCCRRK 124 Query: 137 GGRV--KTEHKAL 147 R ++E KA+ Sbjct: 125 RSRKPDRSEEKAM 137 >gi|109240552 RUN and FYVE domain-containing 2 isoform b [Homo sapiens] Length = 403 Score = 33.1 bits (74), Expect = 1.1 Identities = 36/149 (24%), Positives = 69/149 (46%), Gaps = 18/149 (12%) Query: 569 EEHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQI-Q 627 ++HL++ + + ELQ+ K Q LD + + ARR L S L++ + VQ+ Sbjct: 236 QQHLEVTKVD--VETELQTYKHSRQGLDEMYNEARRQLR--DESQLRQDVENELAVQVSM 291 Query: 628 RPVVKTSMEQLAQELQ-------GLAQAQD-----NSVLGQRLQEEAQGLRNLHQEKVVP 675 + ++ +M+ L +++ GL Q + N + Q+LQ GL+ E + Sbjct: 292 KHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKE-KNEIIAR 350 Query: 676 QQSLVAKLNLSVRALESSAPNLQLETSDV 704 + K+ ++R LE S +L +T + Sbjct: 351 LEEKTNKITAAMRQLEQSDNDLLTQTRTI 379 >gi|222418604 hypothetical protein LOC257407 [Homo sapiens] Length = 295 Score = 32.7 bits (73), Expect = 1.4 Identities = 32/115 (27%), Positives = 46/115 (40%), Gaps = 1/115 (0%) Query: 286 AIREHRDRLLELLQEARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFS 345 A RE R RL E+L++ R + AL E G + + P + + L+ V Sbjct: 117 AAREPRRRLREMLRDVRGRRRAGAALVGVLVAEAGPEDAVAPGLRLLEALLRAVFGRQAG 176 Query: 346 SMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRW 400 VQ + LPA ++ + L+ A A QP G PGL A W Sbjct: 177 GPVQAA-AYCPGLPASCLAVQAAACRALQAAGAGQPVEGAWERPGLPGLLACFSW 230 >gi|105990532 apolipoprotein B precursor [Homo sapiens] Length = 4563 Score = 32.7 bits (73), Expect = 1.4 Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 7/132 (5%) Query: 450 GIWGLSARDDPSHPEAKGEAGARF----LMAGVGLSFLFAAPLILLVFATFLVGGNVQTL 505 G +GLS + DP+ GE+ RF L ++ + + L + L G ++ Sbjct: 1499 GTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQSGIIKNT 1558 Query: 506 VCRSWENGELFEFADTPGNLP--PSMNLSQLLGLRKNISIHQAYQQCKEGAALWTVLQLN 563 +EN EL +DT G + N + ++N + YQ E +++L + Sbjct: 1559 ASLKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGS 1618 Query: 564 -DSYDLEEHLDI 574 +S+ LE + DI Sbjct: 1619 LNSHGLELNADI 1630 >gi|45439359 triple functional domain (PTPRF interacting) [Homo sapiens] Length = 3097 Score = 32.7 bits (73), Expect = 1.4 Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 22/163 (13%) Query: 276 LQAGQQDLEPAIREHRDRLLELLQEARCQGDCAGALSWARTLE--LGADFSQVPSVDHVL 333 L QQ+L+ A +HR L + +Q Q + L W R E L A S+ Sbjct: 885 LHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEA- 943 Query: 334 HQLKGVPEANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPG 393 QL+ E F +++ + +A+Q + + +A + +R AE Sbjct: 944 EQLQREHE-QFQHAIEKTHQ--------SALQVQQKAEAMLQANHYDMDMIRDCAE---- 990 Query: 394 LEAASRWAQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVV 436 + AS W Q + ++E+ + V Y+T + CSV+ Sbjct: 991 -KVASHWQQLMLKMEDRLKLVNASVAFYKTSEQV-----CSVL 1027 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.134 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,507,001 Number of Sequences: 37866 Number of extensions: 1249520 Number of successful extensions: 4485 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 70 Number of HSP's that attempted gapping in prelim test: 4350 Number of HSP's gapped (non-prelim): 161 length of query: 834 length of database: 18,247,518 effective HSP length: 111 effective length of query: 723 effective length of database: 14,044,392 effective search space: 10154095416 effective search space used: 10154095416 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.