Guide to the Human Genome
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Search of human proteins with 21389617

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21389617 apoptosis-inducing factor,
mitochondrion-associated, 3 isoform 1 [Homo sapiens]
         (605 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21389617 apoptosis-inducing factor, mitochondrion-associated,...  1210   0.0  
gi|65787454 apoptosis-inducing factor, mitochondrion-associated,...  1190   0.0  
gi|226437568 apoptosis-inducing factor, mitochondrion-associated...  1183   0.0  
gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens]          113   6e-25
gi|4757732 programmed cell death 8 isoform 1 [Homo sapiens]           112   8e-25
gi|195927006 programmed cell death 8 isoform 5 [Homo sapiens]          78   2e-14
gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens]    64   3e-10
gi|50301238 glutathione reductase [Homo sapiens]                       53   9e-07
gi|14318424 apoptosis-inducing factor (AIF)-like mitchondrion-as...    49   2e-05
gi|51036596 pyridine nucleotide-disulphide oxidoreductase domain...    47   4e-05
gi|197100550 Rieske (Fe-S) domain containing isoform 1 [Homo sap...    39   0.011
gi|197100526 Rieske (Fe-S) domain containing isoform 1 [Homo sap...    39   0.011
gi|28603828 Rieske (Fe-S) domain containing isoform 2 [Homo sapi...    39   0.011
gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]           39   0.014
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]          39   0.014
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]          39   0.014
gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]           39   0.014
gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]           39   0.014
gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]           37   0.069
gi|10140847 homeobox A2 [Homo sapiens]                                 34   0.44 
gi|28559080 spermine oxidase isoform 4 [Homo sapiens]                  33   0.76 
gi|28559078 spermine oxidase isoform 3 [Homo sapiens]                  33   0.76 
gi|28559076 spermine oxidase isoform 2 [Homo sapiens]                  33   0.76 
gi|28559074 spermine oxidase isoform 1 [Homo sapiens]                  33   0.76 
gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]       33   0.99 
gi|62865635 squalene epoxidase [Homo sapiens]                          32   1.3  
gi|15082234 lactate dehydrogenase A-like 6B [Homo sapiens]             32   1.7  
gi|221136809 lactate dehydrogenase A-like 6A [Homo sapiens]            32   2.2  
gi|47059044 lactate dehydrogenase A-like 6A [Homo sapiens]             32   2.2  
gi|23821023 interleukin 4 induced 1 isoform 1 precursor [Homo sa...    32   2.2  

>gi|21389617 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 1 [Homo sapiens]
          Length = 605

 Score = 1210 bits (3131), Expect = 0.0
 Identities = 605/605 (100%), Positives = 605/605 (100%)

Query: 1   MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHP 60
           MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHP
Sbjct: 1   MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHP 60

Query: 61  YPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGV 120
           YPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGV
Sbjct: 61  YPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGV 120

Query: 121 LSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKV 180
           LSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKV
Sbjct: 121 LSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKV 180

Query: 181 MAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSK 240
           MAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSK
Sbjct: 181 MAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSK 240

Query: 241 SLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSS 300
           SLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSS
Sbjct: 241 SLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSS 300

Query: 301 PKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSV 360
           PKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSV
Sbjct: 301 PKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSV 360

Query: 361 VELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRA 420
           VELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRA
Sbjct: 361 VELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRA 420

Query: 421 DVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRK 480
           DVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRK
Sbjct: 421 DVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRK 480

Query: 481 VNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDL 540
           VNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDL
Sbjct: 481 VNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDL 540

Query: 541 EELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWL 600
           EELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWL
Sbjct: 541 EELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWL 600

Query: 601 TGKGS 605
           TGKGS
Sbjct: 601 TGKGS 605


>gi|65787454 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 2 [Homo sapiens]
          Length = 598

 Score = 1190 bits (3078), Expect = 0.0
 Identities = 598/605 (98%), Positives = 598/605 (98%), Gaps = 7/605 (1%)

Query: 1   MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHP 60
           MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHP
Sbjct: 1   MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHP 60

Query: 61  YPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGV 120
           YPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGV
Sbjct: 61  YPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGV 120

Query: 121 LSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKV 180
           LSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKV
Sbjct: 121 LSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKV 180

Query: 181 MAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSK 240
           MAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSK
Sbjct: 181 MAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSK 240

Query: 241 SLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSS 300
           SLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSS
Sbjct: 241 SLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSS 300

Query: 301 PKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSV 360
           PKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSV
Sbjct: 301 PKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSV 360

Query: 361 VELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRA 420
           VELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRA
Sbjct: 361 VELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRA 420

Query: 421 DVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRK 480
           DVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRK
Sbjct: 421 DVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRK 480

Query: 481 VNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDL 540
           VNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDL
Sbjct: 481 VNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDL 540

Query: 541 EELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWL 600
           EELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVE       TGDMSWL
Sbjct: 541 EELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVE-------TGDMSWL 593

Query: 601 TGKGS 605
           TGKGS
Sbjct: 594 TGKGS 598


>gi|226437568 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 3 [Homo sapiens]
          Length = 604

 Score = 1183 bits (3061), Expect = 0.0
 Identities = 598/611 (97%), Positives = 598/611 (97%), Gaps = 13/611 (2%)

Query: 1   MGGCFSKPKP------VELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEER 54
           MGGCFSKPKP      VELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEER
Sbjct: 1   MGGCFSKPKPGAALPTVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEER 60

Query: 55  LSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGA 114
           LSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGA
Sbjct: 61  LSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGA 120

Query: 115 PLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQL 174
           PLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQL
Sbjct: 121 PLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQL 180

Query: 175 QRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYD 234
           QRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYD
Sbjct: 181 QRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYD 240

Query: 235 RPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLL 294
           RPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLL
Sbjct: 241 RPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLL 300

Query: 295 LAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEK 354
           LAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEK
Sbjct: 301 LAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEK 360

Query: 355 AHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKS 414
           AHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKS
Sbjct: 361 AHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKS 420

Query: 415 SKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLA 474
           SKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLA
Sbjct: 421 SKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLA 480

Query: 475 WRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDV 534
           WRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDV
Sbjct: 481 WRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDV 540

Query: 535 IIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKT 594
           IIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVE       T
Sbjct: 541 IIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVE-------T 593

Query: 595 GDMSWLTGKGS 605
           GDMSWLTGKGS
Sbjct: 594 GDMSWLTGKGS 604


>gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens]
          Length = 609

 Score =  113 bits (282), Expect = 6e-25
 Identities = 114/418 (27%), Positives = 179/418 (42%), Gaps = 51/418 (12%)

Query: 147 GLDSLHKFQVKIEKEKVY-VRASKQALQLQRRTKVMAKCIS-----PSAGYSSSTNVLIV 200
           G    + ++   E EK Y  R S   L  +++ K  A   S     P     S    L++
Sbjct: 74  GAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLI 133

Query: 201 GAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSL-----------------D 243
           G G A    A ++R      R+++ + D  LPY RP LSK L                 +
Sbjct: 134 GGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWN 193

Query: 244 TQPEQLALRPKEFFRAY---------GIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLL 294
            +   +  +P  F+ +          G+ VLT  +VV +DVR   V   DG ++ Y K L
Sbjct: 194 GKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCL 253

Query: 295 LAPGSSPKTLSC---KGKEVENVFTI-RTPEDANRVVRLARG-RNVVVVGAGFLGMEVAA 349
           +A G +P++LS     G EV++  T+ R   D   + +++R  +++ ++G GFLG E+A 
Sbjct: 254 IATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELAC 313

Query: 350 YLTEKAHSV--SVVEL--EETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEG 405
            L  KA ++   V++L  E+    + L E +    M+      VK      V  +    G
Sbjct: 314 ALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSG 373

Query: 406 KLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSR-GFIPVNKMMQTNVPGVFA 464
           KL  + LK  + V  D  V  +G  P     +  G+ +DS  G   VN  +Q     ++ 
Sbjct: 374 KLL-IKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQAR-SNIWV 431

Query: 465 AGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSL 522
           AGDA  F       R+V   H   A   GR+A +NM       +  PY   +MF   L
Sbjct: 432 AGDAACFYDIKLGRRRVE--HHDHAVVSGRLAGENMTG-----AAKPYWHQSMFWSDL 482


>gi|4757732 programmed cell death 8 isoform 1 [Homo sapiens]
          Length = 613

 Score =  112 bits (281), Expect = 8e-25
 Identities = 113/413 (27%), Positives = 178/413 (43%), Gaps = 51/413 (12%)

Query: 152 HKFQVKIEKEKVY-VRASKQALQLQRRTKVMAKCIS-----PSAGYSSSTNVLIVGAGAA 205
           + ++   E EK Y  R S   L  +++ K  A   S     P     S    L++G G A
Sbjct: 83  YAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLIGGGTA 142

Query: 206 GLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSL-----------------DTQPEQ 248
               A ++R      R+++ + D  LPY RP LSK L                 + +   
Sbjct: 143 AFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERS 202

Query: 249 LALRPKEFFRAY---------GIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGS 299
           +  +P  F+ +          G+ VLT  +VV +DVR   V   DG ++ Y K L+A G 
Sbjct: 203 IYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGG 262

Query: 300 SPKTLSC---KGKEVENVFTI-RTPEDANRVVRLARG-RNVVVVGAGFLGMEVAAYLTEK 354
           +P++LS     G EV++  T+ R   D   + +++R  +++ ++G GFLG E+A  L  K
Sbjct: 263 TPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRK 322

Query: 355 AHSV--SVVEL--EETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEV 410
           A ++   V++L  E+    + L E +    M+      VK      V  +    GKL  +
Sbjct: 323 ARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLL-I 381

Query: 411 VLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSR-GFIPVNKMMQTNVPGVFAAGDAV 469
            LK  + V  D  V  +G  P     +  G+ +DS  G   VN  +Q     ++ AGDA 
Sbjct: 382 KLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQAR-SNIWVAGDAA 440

Query: 470 TFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSL 522
            F       R+V   H   A   GR+A +NM       +  PY   +MF   L
Sbjct: 441 CFYDIKLGRRRVE--HHDHAVVSGRLAGENMTG-----AAKPYWHQSMFWSDL 486


>gi|195927006 programmed cell death 8 isoform 5 [Homo sapiens]
          Length = 324

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 67/240 (27%), Positives = 109/240 (45%), Gaps = 37/240 (15%)

Query: 152 HKFQVKIEKEKVY-VRASKQALQLQRRTKVMAKCIS-----PSAGYSSSTNVLIVGAGAA 205
           + ++   E EK Y  R S   L  +++ K  A   S     P     S    L++G G A
Sbjct: 83  YAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLIGGGTA 142

Query: 206 GLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSL-----------------DTQPEQ 248
               A ++R      R+++ + D  LPY RP LSK L                 + +   
Sbjct: 143 AFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERS 202

Query: 249 LALRPKEFFRAY---------GIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGS 299
           +  +P  F+ +          G+ VLT  +VV +DVR   V   DG ++ Y K L+A G 
Sbjct: 203 IYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGG 262

Query: 300 SPKTLSC---KGKEVENVFTI-RTPEDANRVVRLARG-RNVVVVGAGFLGMEVAAYLTEK 354
           +P++LS     G EV++  T+ R   D   + +++R  +++ ++G GFLG E+A  L  K
Sbjct: 263 TPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRK 322


>gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens]
          Length = 509

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 44/146 (30%), Positives = 73/146 (50%), Gaps = 7/146 (4%)

Query: 335 VVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ 394
           +VV+GAG +G+E+ +        V+ VE         +   + +   ++ +    KF + 
Sbjct: 216 MVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLN 275

Query: 395 TEVS-ELRGQEGKLKEVVLKSS----KVVRADVCVVGIGAVPATGFL--RQSGIGLDSRG 447
           T+V+   +  +GK+   +  +S    +V+  DV +V IG  P T  L   + GI LD RG
Sbjct: 276 TKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRG 335

Query: 448 FIPVNKMMQTNVPGVFAAGDAVTFPL 473
            IPVN   QT +P ++A GD V  P+
Sbjct: 336 RIPVNTRFQTKIPNIYAIGDVVAGPM 361


>gi|50301238 glutathione reductase [Homo sapiens]
          Length = 522

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 62/347 (17%)

Query: 187 PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIV-------LCT------------- 226
           P+AG  +S + L++G G+ GL  A    + G    +V        C              
Sbjct: 57  PAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNT 116

Query: 227 ------LDRHLPYDRPK---------LSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVV 271
                 +  H  Y  P          + +  D    +L    +       IE++      
Sbjct: 117 AVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAF 176

Query: 272 TVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLAR 331
           T D   K  +   G K     +L+A G  P T      ++       T +   ++  L  
Sbjct: 177 TSD--PKPTIEVSGKKYTAPHILIATGGMPSTPH--ESQIPGASLGITSDGFFQLEELP- 231

Query: 332 GRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRF-------LGERVGRALMKMF 384
           GR+V+V GAG++ +E+A  L+      S++   +   R F         E +  A +++ 
Sbjct: 232 GRSVIV-GAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVL 290

Query: 385 ENNRVKFYMQT----EVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATG--FLRQ 438
           + ++VK   +T    EVS +    G+L  + +    +   D  +  IG VP T    L +
Sbjct: 291 KFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTM----IPDVDCLLWAIGRVPNTKDLSLNK 346

Query: 439 SGIGLDSRGFIPVNKMMQTNVPGVFAAGD----AVTFPLAWRNNRKV 481
            GI  D +G I V++   TNV G++A GD    A+  P+A    RK+
Sbjct: 347 LGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKL 393


>gi|14318424 apoptosis-inducing factor (AIF)-like
           mitchondrion-associated inducer of death [Homo sapiens]
          Length = 373

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 70/290 (24%), Positives = 130/290 (44%), Gaps = 27/290 (9%)

Query: 192 SSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLAL 251
           S + +V+IVG G  G+  A  L  +  +   +L  +     ++   L  S++T       
Sbjct: 9   SGALHVVIVGGGFGGIAAASQL--QALNVPFMLVDMKDSFHHNVAALRASVETG------ 60

Query: 252 RPKEFFRAYGI---EVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKG 308
             K+ F +Y +   +   +  VV +D++ + V+ + G  L +S L+LA GS+        
Sbjct: 61  FAKKTFISYSVTFKDNFRQGLVVGIDLKNQMVLLQGGEALPFSHLILATGSTGPFPGKFN 120

Query: 309 KEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEK--------AHS-VS 359
           +       I+  ED  R V+  R R +VVVG G  G+E+AA +  +         HS V+
Sbjct: 121 EVSSQQAAIQAYEDMVRQVQ--RSRFIVVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVA 178

Query: 360 VVELEETP-FRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVV 418
           + + E  P  R+ + E + R  +++  + RV    +  ++E R     +K    K ++V 
Sbjct: 179 LADKELLPSVRQEVKEILLRKGVQLLLSERVSNLEELPLNEYREY---IKVQTDKGTEVA 235

Query: 419 RADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQT-NVPGVFAAGD 467
              V +     + ++ + +     L S G + VN+ +Q      V+A GD
Sbjct: 236 TNLVILCTGIKINSSAYRKAFESRLASSGALRVNEHLQVEGHSNVYAIGD 285


>gi|51036596 pyridine nucleotide-disulphide oxidoreductase domain 1
           [Homo sapiens]
          Length = 500

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 18/167 (10%)

Query: 187 PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLP-----YDRPKLSKS 241
           P+AG       ++VG G AG+ CAE L     S+ I+L T    +          K+ + 
Sbjct: 8   PTAG-----KFVVVGGGIAGVTCAEQLATHFPSEDILLVTASPVIKAVTNFKQISKILEE 62

Query: 242 LDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSP 301
            D + +   +  K F     I+V+ E+ V  +      +V +DG +  Y KL L  G+ P
Sbjct: 63  FDVEEQSSTMLGKRF---PNIKVI-ESGVKQLKSEEHCIVTEDGNQHVYKKLCLCAGAKP 118

Query: 302 KTLSCKGKEVENVFTIRTPEDANRVVR-LARGRNVVVVGAGFLGMEV 347
           K L C+G     V  IR  + A    + L + + ++++G G + +E+
Sbjct: 119 K-LICEGNPY--VLGIRDTDSAQEFQKQLTKAKRIMIIGNGGIALEL 162



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 42/164 (25%), Positives = 62/164 (37%), Gaps = 21/164 (12%)

Query: 410 VVLKSSKVVRADVCVVGIGAVP-ATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDA 468
           V L + K+   D  V   G  P    FL  +   L   G + V+  M T++P ++AAGD 
Sbjct: 300 VELTNEKIYGCDFIVSATGVTPNVEPFLHGNSFDLGEDGGLKVDDHMHTSLPDIYAAGDI 359

Query: 469 VT----FPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRY 524
            T        W+  R      W  A   G  AA+ M A  +  S        +F    ++
Sbjct: 360 CTTSWQLSPVWQQMRL-----WTQARQMGWYAAKCMAAASSGDSIDMDFSFELFAHVTKF 414

Query: 525 AGYGEGFDDVII------QGDLEELKFVAFYTKGDEVIAVASMN 562
             Y      V++      QG   + + +   TKG E I V   N
Sbjct: 415 FNY-----KVVLLGKYNAQGLGSDHELMLRCTKGREYIKVVMQN 453


>gi|197100550 Rieske (Fe-S) domain containing isoform 1 [Homo
           sapiens]
          Length = 210

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 62  PSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVL 121
           P  ++     V    D++  +     +   +V++    GE+HA+  +C H G PL  G +
Sbjct: 63  PEKREYSSVCVGREDDIKKSERMTAVVHDREVVIFYHKGEYHAMDIRCYHSGGPLHLGDI 122

Query: 122 ----SRGRVRCPWHGACFNISTGD 141
                R  + CPWH     ++TG+
Sbjct: 123 EDFDGRPCIVCPWHKYKITLATGE 146


>gi|197100526 Rieske (Fe-S) domain containing isoform 1 [Homo
           sapiens]
          Length = 210

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 62  PSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVL 121
           P  ++     V    D++  +     +   +V++    GE+HA+  +C H G PL  G +
Sbjct: 63  PEKREYSSVCVGREDDIKKSERMTAVVHDREVVIFYHKGEYHAMDIRCYHSGGPLHLGDI 122

Query: 122 ----SRGRVRCPWHGACFNISTGD 141
                R  + CPWH     ++TG+
Sbjct: 123 EDFDGRPCIVCPWHKYKITLATGE 146


>gi|28603828 Rieske (Fe-S) domain containing isoform 2 [Homo
           sapiens]
          Length = 157

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 62  PSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVL 121
           P  ++     V    D++  +     +   +V++    GE+HA+  +C H G PL  G +
Sbjct: 10  PEKREYSSVCVGREDDIKKSERMTAVVHDREVVIFYHKGEYHAMDIRCYHSGGPLHLGDI 69

Query: 122 ----SRGRVRCPWHGACFNISTGD 141
                R  + CPWH     ++TG+
Sbjct: 70  EDFDGRPCIVCPWHKYKITLATGE 93


>gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 13/143 (9%)

Query: 336 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ- 394
           +VVGA ++ +E A +L      V+V  +  +   R   + +   + +  E + +KF  Q 
Sbjct: 194 LVVGASYVALECAGFLAGIGLDVTV--MVRSILLRGFDQDMANKIGEHMEEHGIKFIRQF 251

Query: 395 --TEVSELR-GQEGKLKEVV--LKSSKVVRAD--VCVVGIGAVPATGFLRQSGIGL---D 444
              +V ++  G  G+L+ V     S +++  +    ++ IG    T  +    +G+   +
Sbjct: 252 VPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINE 311

Query: 445 SRGFIPVNKMMQTNVPGVFAAGD 467
             G IPV    QTNVP ++A GD
Sbjct: 312 KTGKIPVTDEEQTNVPYIYAIGD 334


>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
          Length = 649

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 13/143 (9%)

Query: 336 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ- 394
           +VVGA ++ +E A +L      V+V  +  +   R   + +   + +  E + +KF  Q 
Sbjct: 344 LVVGASYVALECAGFLAGIGLDVTV--MVRSILLRGFDQDMANKIGEHMEEHGIKFIRQF 401

Query: 395 --TEVSELR-GQEGKLKEVV--LKSSKVVRAD--VCVVGIGAVPATGFLRQSGIGL---D 444
              +V ++  G  G+L+ V     S +++  +    ++ IG    T  +    +G+   +
Sbjct: 402 VPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINE 461

Query: 445 SRGFIPVNKMMQTNVPGVFAAGD 467
             G IPV    QTNVP ++A GD
Sbjct: 462 KTGKIPVTDEEQTNVPYIYAIGD 484


>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
          Length = 551

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 13/143 (9%)

Query: 336 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ- 394
           +VVGA ++ +E A +L      V+V  +  +   R   + +   + +  E + +KF  Q 
Sbjct: 246 LVVGASYVALECAGFLAGIGLDVTV--MVRSILLRGFDQDMANKIGEHMEEHGIKFIRQF 303

Query: 395 --TEVSELR-GQEGKLKEVV--LKSSKVVRAD--VCVVGIGAVPATGFLRQSGIGL---D 444
              +V ++  G  G+L+ V     S +++  +    ++ IG    T  +    +G+   +
Sbjct: 304 VPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINE 363

Query: 445 SRGFIPVNKMMQTNVPGVFAAGD 467
             G IPV    QTNVP ++A GD
Sbjct: 364 KTGKIPVTDEEQTNVPYIYAIGD 386


>gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 13/143 (9%)

Query: 336 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ- 394
           +VVGA ++ +E A +L      V+V  +  +   R   + +   + +  E + +KF  Q 
Sbjct: 194 LVVGASYVALECAGFLAGIGLDVTV--MVRSILLRGFDQDMANKIGEHMEEHGIKFIRQF 251

Query: 395 --TEVSELR-GQEGKLKEVV--LKSSKVVRAD--VCVVGIGAVPATGFLRQSGIGL---D 444
              +V ++  G  G+L+ V     S +++  +    ++ IG    T  +    +G+   +
Sbjct: 252 VPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINE 311

Query: 445 SRGFIPVNKMMQTNVPGVFAAGD 467
             G IPV    QTNVP ++A GD
Sbjct: 312 KTGKIPVTDEEQTNVPYIYAIGD 334


>gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 13/143 (9%)

Query: 336 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ- 394
           +VVGA ++ +E A +L      V+V  +  +   R   + +   + +  E + +KF  Q 
Sbjct: 194 LVVGASYVALECAGFLAGIGLDVTV--MVRSILLRGFDQDMANKIGEHMEEHGIKFIRQF 251

Query: 395 --TEVSELR-GQEGKLKEVV--LKSSKVVRAD--VCVVGIGAVPATGFLRQSGIGL---D 444
              +V ++  G  G+L+ V     S +++  +    ++ IG    T  +    +G+   +
Sbjct: 252 VPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINE 311

Query: 445 SRGFIPVNKMMQTNVPGVFAAGD 467
             G IPV    QTNVP ++A GD
Sbjct: 312 KTGKIPVTDEEQTNVPYIYAIGD 334


>gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]
          Length = 524

 Score = 36.6 bits (83), Expect = 0.069
 Identities = 56/244 (22%), Positives = 98/244 (40%), Gaps = 34/244 (13%)

Query: 336 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQT 395
           +VVGA ++ +E A +LT      +++ +   P R F  +++   +++   ++  +F    
Sbjct: 222 LVVGASYVALECAGFLTGIGLDTTIM-MRSIPLRGF-DQQMSSMVIEHMASHGTRFLRGC 279

Query: 396 EVSELRGQEGKLKEVVLKSSKVVRA-----DVCVVGIGAVPATGFLRQSGIGLDS---RG 447
             S +R       +V  + S   +      D  +  IG VP T  L     G+D+     
Sbjct: 280 APSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQ 339

Query: 448 FIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEM 507
            I V+    T+VP ++A GD V         R    P   +A   GR+  Q +    +++
Sbjct: 340 KILVDSREATSVPHIYAIGDVV-------EGRPELTP---IAIMAGRLLVQRLFGGSSDL 389

Query: 508 STVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIV 567
                + T +F   L Y   G           L E + VA +  G E + V   +Y P+ 
Sbjct: 390 MDYDNVPTTVF-TPLEYGCVG-----------LSEEEAVARH--GQEHVEVYHAHYKPLE 435

Query: 568 SKVA 571
             VA
Sbjct: 436 FTVA 439


>gi|10140847 homeobox A2 [Homo sapiens]
          Length = 376

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 14/114 (12%)

Query: 378 RALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGF-- 435
           R +   F+N R+K   QT+  E +  EGK K   L+ S+ V  D           T F  
Sbjct: 185 RQVKVWFQNRRMKHKRQTQCKENQNSEGKCKS--LEDSEKVEED-------EEEKTLFEQ 235

Query: 436 -LRQSGIGLDSRGF-IPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQ 487
            L  SG  L+  G+    N + Q   P     GD+ +FP++   + + N+ H+Q
Sbjct: 236 ALSVSGALLEREGYTFQQNALSQQQAPNGH-NGDSQSFPVSPLTSNEKNLKHFQ 288


>gi|28559080 spermine oxidase isoform 4 [Homo sapiens]
          Length = 532

 Score = 33.1 bits (74), Expect = 0.76
 Identities = 14/28 (50%), Positives = 21/28 (75%)

Query: 197 VLIVGAGAAGLVCAETLRQEGFSDRIVL 224
           V+++GAG AGL  A+ L ++GF+D  VL
Sbjct: 27  VVVIGAGLAGLAAAKALLEQGFTDVTVL 54


>gi|28559078 spermine oxidase isoform 3 [Homo sapiens]
          Length = 190

 Score = 33.1 bits (74), Expect = 0.76
 Identities = 14/28 (50%), Positives = 21/28 (75%)

Query: 197 VLIVGAGAAGLVCAETLRQEGFSDRIVL 224
           V+++GAG AGL  A+ L ++GF+D  VL
Sbjct: 27  VVVIGAGLAGLAAAKALLEQGFTDVTVL 54


>gi|28559076 spermine oxidase isoform 2 [Homo sapiens]
          Length = 502

 Score = 33.1 bits (74), Expect = 0.76
 Identities = 14/28 (50%), Positives = 21/28 (75%)

Query: 197 VLIVGAGAAGLVCAETLRQEGFSDRIVL 224
           V+++GAG AGL  A+ L ++GF+D  VL
Sbjct: 27  VVVIGAGLAGLAAAKALLEQGFTDVTVL 54


>gi|28559074 spermine oxidase isoform 1 [Homo sapiens]
          Length = 555

 Score = 33.1 bits (74), Expect = 0.76
 Identities = 14/28 (50%), Positives = 21/28 (75%)

Query: 197 VLIVGAGAAGLVCAETLRQEGFSDRIVL 224
           V+++GAG AGL  A+ L ++GF+D  VL
Sbjct: 27  VVVIGAGLAGLAAAKALLEQGFTDVTVL 54


>gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]
          Length = 1021

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 4/64 (6%)

Query: 45  TARHFHTEERLSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHA 104
           T   FHT +R    H     QD  +  + +V+D + G+       W    L+  NG +H 
Sbjct: 738 TGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEW----LLSTNGTWHK 793

Query: 105 LGHK 108
           LG K
Sbjct: 794 LGEK 797


>gi|62865635 squalene epoxidase [Homo sapiens]
          Length = 574

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 16/40 (40%), Positives = 24/40 (60%)

Query: 335 VVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGE 374
           V++VGAG LG  +AA L+     V+V+E +     R +GE
Sbjct: 126 VIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGE 165


>gi|15082234 lactate dehydrogenase A-like 6B [Homo sapiens]
          Length = 381

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 13/34 (38%), Positives = 21/34 (61%)

Query: 195 TNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLD 228
           + V I+G G+ G+ CA ++  +G SD + L  LD
Sbjct: 70  SKVSIIGTGSVGMACAISILLKGLSDELALVDLD 103


>gi|221136809 lactate dehydrogenase A-like 6A [Homo sapiens]
          Length = 332

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 13/32 (40%), Positives = 21/32 (65%)

Query: 197 VLIVGAGAAGLVCAETLRQEGFSDRIVLCTLD 228
           + IVG G+ G+ CA ++  +G SD +VL  +D
Sbjct: 23  ISIVGTGSVGVACAISILLKGLSDELVLVDVD 54


>gi|47059044 lactate dehydrogenase A-like 6A [Homo sapiens]
          Length = 332

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 13/32 (40%), Positives = 21/32 (65%)

Query: 197 VLIVGAGAAGLVCAETLRQEGFSDRIVLCTLD 228
           + IVG G+ G+ CA ++  +G SD +VL  +D
Sbjct: 23  ISIVGTGSVGVACAISILLKGLSDELVLVDVD 54


>gi|23821023 interleukin 4 induced 1 isoform 1 precursor [Homo
           sapiens]
          Length = 567

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 13/37 (35%), Positives = 23/37 (62%)

Query: 328 RLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELE 364
           R  + + V+VVGAG  G+  A  L++  H V+++E +
Sbjct: 55  RTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD 91


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,173,825
Number of Sequences: 37866
Number of extensions: 1046805
Number of successful extensions: 2555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2500
Number of HSP's gapped (non-prelim): 52
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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