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Search of human proteins with 21389501
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389501 coiled-coil domain containing 52 [Homo sapiens]
(855 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389501 coiled-coil domain containing 52 [Homo sapiens] 1682 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 45 3e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 41 0.004
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 41 0.004
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 41 0.004
gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [... 41 0.004
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 41 0.004
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 41 0.005
gi|112420968 coiled-coil domain containing 158 [Homo sapiens] 41 0.005
gi|55770834 centromere protein F [Homo sapiens] 40 0.007
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 40 0.009
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 40 0.009
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 40 0.009
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 40 0.009
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 40 0.009
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 40 0.009
gi|114842396 ankyrin-repeat and fibronectin type III domain cont... 39 0.027
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 38 0.035
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 38 0.046
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 38 0.046
gi|130980075 centromere protein J [Homo sapiens] 38 0.046
gi|16262452 cingulin [Homo sapiens] 38 0.046
gi|203096856 kinesin family member 7 [Homo sapiens] 38 0.046
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 37 0.060
gi|155969714 nuclear protein, ataxia-telangiectasia locus [Homo... 37 0.10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 37 0.10
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 37 0.10
gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens] 36 0.13
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 36 0.17
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 36 0.17
>gi|21389501 coiled-coil domain containing 52 [Homo sapiens]
Length = 855
Score = 1682 bits (4356), Expect = 0.0
Identities = 855/855 (100%), Positives = 855/855 (100%)
Query: 1 MSFVRVNRCGPRVGVRKTPKVKKKKTSVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKN 60
MSFVRVNRCGPRVGVRKTPKVKKKKTSVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKN
Sbjct: 1 MSFVRVNRCGPRVGVRKTPKVKKKKTSVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKN 60
Query: 61 RALVHWELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAK 120
RALVHWELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAK
Sbjct: 61 RALVHWELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAK 120
Query: 121 ELFPRRRTGFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQ 180
ELFPRRRTGFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQ
Sbjct: 121 ELFPRRRTGFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQ 180
Query: 181 SGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTP 240
SGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTP
Sbjct: 181 SGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTP 240
Query: 241 SSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRK 300
SSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRK
Sbjct: 241 SSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRK 300
Query: 301 PNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQ 360
PNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQ
Sbjct: 301 PNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQ 360
Query: 361 SSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILR 420
SSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILR
Sbjct: 361 SSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILR 420
Query: 421 LREENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGATGRRVMDSPER 480
LREENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGATGRRVMDSPER
Sbjct: 421 LREENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGATGRRVMDSPER 480
Query: 481 PVVNANVSVPLMFREEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPAVLLTPPR 540
PVVNANVSVPLMFREEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPAVLLTPPR
Sbjct: 481 PVVNANVSVPLMFREEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPAVLLTPPR 540
Query: 541 QKSNLKFSPLQDVLRRTVQTRPAPRLPPTVEIIEKEQNWEEKTLPIDTDIQNSSEENRLF 600
QKSNLKFSPLQDVLRRTVQTRPAPRLPPTVEIIEKEQNWEEKTLPIDTDIQNSSEENRLF
Sbjct: 541 QKSNLKFSPLQDVLRRTVQTRPAPRLPPTVEIIEKEQNWEEKTLPIDTDIQNSSEENRLF 600
Query: 601 TQRWRVSHMGEDLENKTQAPFVNLSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTNE 660
TQRWRVSHMGEDLENKTQAPFVNLSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTNE
Sbjct: 601 TQRWRVSHMGEDLENKTQAPFVNLSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTNE 660
Query: 661 SLIQRKDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTSTFPVAQ 720
SLIQRKDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTSTFPVAQ
Sbjct: 661 SLIQRKDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTSTFPVAQ 720
Query: 721 SLTPGSMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSPPMSPVQLPLRAWTEGAKRT 780
SLTPGSMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSPPMSPVQLPLRAWTEGAKRT
Sbjct: 721 SLTPGSMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSPPMSPVQLPLRAWTEGAKRT 780
Query: 781 IEVSIPGAEAPESSKCSTVSPVSGINTRRSSGATGNSCSPLNATSGSGRFTPLNPRAKIE 840
IEVSIPGAEAPESSKCSTVSPVSGINTRRSSGATGNSCSPLNATSGSGRFTPLNPRAKIE
Sbjct: 781 IEVSIPGAEAPESSKCSTVSPVSGINTRRSSGATGNSCSPLNATSGSGRFTPLNPRAKIE 840
Query: 841 KQNEEGWFALSTHVS 855
KQNEEGWFALSTHVS
Sbjct: 841 KQNEEGWFALSTHVS 855
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 45.1 bits (105), Expect = 3e-04
Identities = 77/417 (18%), Positives = 151/417 (36%), Gaps = 46/417 (11%)
Query: 20 KVKKKKTSVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQEKALKRKWRK 79
K+ K+K S+++ T+ DL V L++ + + + L QEK L+ +
Sbjct: 995 KLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLER 1054
Query: 80 QKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNVTVAPDS 139
K + K + ++ +D+ Q+++ L+K + +
Sbjct: 1055 AKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEF-----------------------EL 1091
Query: 140 SQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQSGESENENELDNSLNSQSN 199
SQ ++ + + F + + E QA + E E E+ L + Q
Sbjct: 1092 SQLQAKIDDEQVHSLQFQKKIKELQA----------RIEELEEEIEAEHTLRAKIEKQ-R 1140
Query: 200 TNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSALSSGEQRAALN--ATN 257
++ R L++++E E I+ +++ + + A L AT
Sbjct: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEF-------QKMRRDLEEATLQHEATA 1193
Query: 258 AVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKNISSGS 317
A R + E E +D+ V L K + + N+ ALSK K NI
Sbjct: 1194 ATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTC 1253
Query: 318 TTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLC 377
T D + + + +IH++ + + G ++ + L L S
Sbjct: 1254 RTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLIS---QLTKSKQ 1310
Query: 378 RLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILRLREENAATQARLQQ 434
L + L+E + Q+ +E + + + L R D L + +E A Q L +
Sbjct: 1311 ALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSK 1367
Score = 33.1 bits (74), Expect = 1.1
Identities = 64/332 (19%), Positives = 133/332 (40%), Gaps = 58/332 (17%)
Query: 162 EPQALNDVDGEEEGTVNSQSGESENENELDNSLNSQSNTNTDRFLQQLTE---------- 211
+ Q ++D++ ++ + +Q+GE + E SL SQ + QQL E
Sbjct: 1270 QTQLIHDLN-MQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETK 1328
Query: 212 -------------ENFELISKLWTDIQQ-KIATQSQITPPGTPSSALSSGEQRAALNATN 257
+ +L+ + + + Q+ K Q ++ + + + + A+ T
Sbjct: 1329 AKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTE 1388
Query: 258 ----AVKRLQTRLQP-EESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHA----LSK 308
A K+L RLQ EE+TET +S R Q ++ + ++ H L K
Sbjct: 1389 ELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDK 1448
Query: 309 PKKNI-------------SSGSTTSADLPNRT-NSNLDVLKHMIHEVEHEMEEYERWTGR 354
++N S +A +R+ ++ L +++ EV ++E R
Sbjct: 1449 KQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR---- 1504
Query: 355 EVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDAL 414
E K LQ L + + L+E+E + + + L+ L + ++
Sbjct: 1505 ENKNLQEEIS------DLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHE 1558
Query: 415 TAEILRLREENAATQARLQQYMVTTDEQLISL 446
++ILR++ E + ++ L + ++ DE++ L
Sbjct: 1559 ESKILRVQLELSQVKSELDRKVIEKDEEIEQL 1590
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 41.2 bits (95), Expect = 0.004
Identities = 106/578 (18%), Positives = 236/578 (40%), Gaps = 56/578 (9%)
Query: 185 ENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSAL 244
E + L++ L + +D+ L +L +EN +L +KL ++ + +I + L
Sbjct: 358 ETKTMLEDQLEG-TRARSDK-LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTL 415
Query: 245 SSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLH 304
++++ + + L+ + E +E S +GH +N +LL K +
Sbjct: 416 EMAQKQSMDESLHLGWELEQISRTSELSEAPQKS--LGHEVNELTSSRLL---KLEMENQ 470
Query: 305 ALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQSSQG 364
+L+K + + T+ D S + ++ + ++E E +E + LQ+ Q
Sbjct: 471 SLTKTVEELR----TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Query: 365 LTGFTLSLVSSLCRLVRYLKE-SEIQLRKEVETRQQLEQVLGDHRELID-ALTAEILRLR 422
L+ + + L + + L+E SE Q++ + + L Q + R+ + A + +
Sbjct: 527 LSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Query: 423 EENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQA-SESGATGRRVMDS---- 477
+EN +++ T +L + + ++E++ E G + +
Sbjct: 587 KENKILHESIKE----TSSKLSKIEFEKRQI-----KKELEHYKEKGERAEELENELHHL 637
Query: 478 -PERPVVNANVSVPLMFREEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPAVLL 536
E ++ ++ + E++ QE ++ +N L K + F+
Sbjct: 638 EKENELLQKKITNLKITCEKIEALEQENSELER-------ENRKLKKTLDS--FKNLTFQ 688
Query: 537 TPPRQKSNLKFSPLQDVLRRTVQT-RPAPRLPPTVEIIEKEQNWEEKTLPIDTDIQNSSE 595
+K N + LRR V++ + A +++ KE E++ L ++ +S
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF 748
Query: 596 ENRLFTQRWRVSHMGEDLENKTQAPFVNLSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQ 655
+ T+R VS+ G D+EN+ L + L NS+ QQ S E+ + Q
Sbjct: 749 KK---TERLEVSYQGLDIENQ------RLQKTLENSNKKIQQLESELQDLEM----ENQT 795
Query: 656 LRTNESLIQRKDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTST 715
L+ N L + K R+ L +N +++ + + + + + + L +Q D T
Sbjct: 796 LQKN--LEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLE 853
Query: 716 FPVAQSLTPGSMEERIAELNRQSMEARGKLLQLIEQQK 753
++ G++E+ L+++ + ++L E +K
Sbjct: 854 ---ENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Score = 39.3 bits (90), Expect = 0.016
Identities = 90/461 (19%), Positives = 186/461 (40%), Gaps = 28/461 (6%)
Query: 47 EDLVRRHEIHKSKNRALVHWELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQ 106
E L + E+ K+ + E+ + L + ++ + N K+ + E+ + + Q
Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Query: 107 DVLEKSDHLIAAAKELFPRRRTGFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQAL 166
+ + + L ++K L + N ++ ++SQ + +D N+ + + +
Sbjct: 795 TLQKNLEELKISSKRLEQLEKE---NKSLEQETSQ----LEKDKKQLEKENKRLRQQAEI 847
Query: 167 NDVDGEEEGTVNSQSGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQ 226
D EE N + G E EN+ + + R L++L +EN EL+ + DI+
Sbjct: 848 KDTTLEEN---NVKIGNLEKENKTLSKEIGIYKESCVR-LKELEKENKELVKRATIDIKT 903
Query: 227 KIATQSQITPPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSY-VVGHVL 285
+ + + + +++ ++ + L E+ST+ DS Y ++ L
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD--DSRYKLLESKL 961
Query: 286 NSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEM 345
S +K L K ++ L A + N + N + LK E E +
Sbjct: 962 ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL---KTVKKNYEALKQRQDE-ERMV 1017
Query: 346 EEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQ--QLEQV 403
+ +G + K + SQ T L + L + R + +Q K+ Q QLE
Sbjct: 1018 QSSPPISGEDNKWERESQETTRELLKVKDRLIEVER--NNATLQAEKQALKTQLKQLETQ 1075
Query: 404 LGDHRELIDALTAEILRLREENAATQ---ARLQQYMVTTDEQLISLTHAIKNCPVINNRQ 460
+ + I AL + + L+E+N Q A+LQ T + Q SL + +N ++ +
Sbjct: 1076 NNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMN--QNAQLLIQQS 1133
Query: 461 EIQ-ASESGATGRRVMDSPERPVVNANVSVPLMFREEVAEF 500
++ +ES R + S ++ + + L+ + +E+
Sbjct: 1134 SLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEY 1174
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 41.2 bits (95), Expect = 0.004
Identities = 106/578 (18%), Positives = 236/578 (40%), Gaps = 56/578 (9%)
Query: 185 ENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSAL 244
E + L++ L + +D+ L +L +EN +L +KL ++ + +I + L
Sbjct: 358 ETKTMLEDQLEG-TRARSDK-LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTL 415
Query: 245 SSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLH 304
++++ + + L+ + E +E S +GH +N +LL K +
Sbjct: 416 EMAQKQSMDESLHLGWELEQISRTSELSEAPQKS--LGHEVNELTSSRLL---KLEMENQ 470
Query: 305 ALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQSSQG 364
+L+K + + T+ D S + ++ + ++E E +E + LQ+ Q
Sbjct: 471 SLTKTVEELR----TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Query: 365 LTGFTLSLVSSLCRLVRYLKE-SEIQLRKEVETRQQLEQVLGDHRELID-ALTAEILRLR 422
L+ + + L + + L+E SE Q++ + + L Q + R+ + A + +
Sbjct: 527 LSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Query: 423 EENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQA-SESGATGRRVMDS---- 477
+EN +++ T +L + + ++E++ E G + +
Sbjct: 587 KENKILHESIKE----TSSKLSKIEFEKRQI-----KKELEHYKEKGERAEELENELHHL 637
Query: 478 -PERPVVNANVSVPLMFREEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPAVLL 536
E ++ ++ + E++ QE ++ +N L K + F+
Sbjct: 638 EKENELLQKKITNLKITCEKIEALEQENSELER-------ENRKLKKTLDS--FKNLTFQ 688
Query: 537 TPPRQKSNLKFSPLQDVLRRTVQT-RPAPRLPPTVEIIEKEQNWEEKTLPIDTDIQNSSE 595
+K N + LRR V++ + A +++ KE E++ L ++ +S
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF 748
Query: 596 ENRLFTQRWRVSHMGEDLENKTQAPFVNLSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQ 655
+ T+R VS+ G D+EN+ L + L NS+ QQ S E+ + Q
Sbjct: 749 KK---TERLEVSYQGLDIENQ------RLQKTLENSNKKIQQLESELQDLEM----ENQT 795
Query: 656 LRTNESLIQRKDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTST 715
L+ N L + K R+ L +N +++ + + + + + + L +Q D T
Sbjct: 796 LQKN--LEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLE 853
Query: 716 FPVAQSLTPGSMEERIAELNRQSMEARGKLLQLIEQQK 753
++ G++E+ L+++ + ++L E +K
Sbjct: 854 ---ENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Score = 38.1 bits (87), Expect = 0.035
Identities = 88/460 (19%), Positives = 184/460 (40%), Gaps = 27/460 (5%)
Query: 47 EDLVRRHEIHKSKNRALVHWELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQ 106
E L + E+ K+ + E+ + L + ++ + N K+ + E+ + + Q
Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Query: 107 DVLEKSDHLIAAAKELFPRRRTGFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQAL 166
+ + + L ++K L + N ++ ++SQ + +D N+ + + +
Sbjct: 795 TLQKNLEELKISSKRLEQLEKE---NKSLEQETSQ----LEKDKKQLEKENKRLRQQAEI 847
Query: 167 NDVDGEEEGTVNSQSGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQ 226
D EE N + G E EN+ + + R L++L +EN EL+ + DI+
Sbjct: 848 KDTTLEEN---NVKIGNLEKENKTLSKEIGIYKESCVR-LKELEKENKELVKRATIDIKT 903
Query: 227 KIATQSQITPPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLN 286
+ + + + +++ ++ + L E+ST+ D ++ L
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD--DRYKLLESKLE 961
Query: 287 SRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEME 346
S +K L K ++ L A + N + N + LK E E ++
Sbjct: 962 STLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL---KTVKKNYEALKQRQDE-ERMVQ 1017
Query: 347 EYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQ--QLEQVL 404
+G + K + SQ T L + L + R + +Q K+ Q QLE
Sbjct: 1018 SSPPISGEDNKWERESQETTRELLKVKDRLIEVER--NNATLQAEKQALKTQLKQLETQN 1075
Query: 405 GDHRELIDALTAEILRLREENAATQ---ARLQQYMVTTDEQLISLTHAIKNCPVINNRQE 461
+ + I AL + + L+E+N Q A+LQ T + Q SL + +N ++ +
Sbjct: 1076 NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMN--QNAQLLIQQSS 1133
Query: 462 IQ-ASESGATGRRVMDSPERPVVNANVSVPLMFREEVAEF 500
++ +ES R + S ++ + + L+ + +E+
Sbjct: 1134 LENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEY 1173
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 41.2 bits (95), Expect = 0.004
Identities = 88/450 (19%), Positives = 187/450 (41%), Gaps = 53/450 (11%)
Query: 27 SVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQ--EKALKRKWRKQKPET 84
S K++ +L +R + + +E+ K R +H + E+A+ K+ + +
Sbjct: 444 SHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKE 503
Query: 85 LNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNVTVAPDSSQGPI 144
L + RL++ +E D +++DVL ++ + + + L + ++ + Q
Sbjct: 504 KELRQLRLAV-RERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLK 562
Query: 145 VVNQDPITQ-SIFNESVIEP--QALNDVDGEEEGTVNSQ-----SGESENENELDNSLNS 196
+ ++ ES+I+ +L+D + E E + G+SE EL L
Sbjct: 563 EEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQR 622
Query: 197 QSNTNTDRFLQQLTEENFELISKLWTDIQ---QKIATQSQITPPGTPSSALSSGEQRAAL 253
+ +R LQ L + + + + +IQ Q ++T+ Q + Q AA
Sbjct: 623 K-----ERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQES-------------QAAAE 664
Query: 254 NATNAVKRLQTRLQP-EESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKN 312
A+ + LQ + DS + N + + + ++ + ++ P ++
Sbjct: 665 KLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRD 724
Query: 313 ISSGSTTSAD--LPNRTNSNLDVLKHMIHEVEHEMEEYE------RWTGREVKGLQSSQG 364
S+ T D +P T +LD + + E+ + EE E R + E+ LQS
Sbjct: 725 DSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMA 784
Query: 365 LTGFTLSL----VSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILR 420
+ L + + SL R IQ+++++ Q++ V + ++ LT E+L
Sbjct: 785 VQEEELQVQAADMESLTR--------NIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLL 836
Query: 421 LREENAATQARLQQYMVTTDEQLISLTHAI 450
LRE+ A+ +++ Q+ +QL+ + +
Sbjct: 837 LREKVASVESQGQEISGNRRQQLLLMLEGL 866
>gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [Homo
sapiens]
Length = 1132
Score = 41.2 bits (95), Expect = 0.004
Identities = 88/450 (19%), Positives = 187/450 (41%), Gaps = 53/450 (11%)
Query: 27 SVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQ--EKALKRKWRKQKPET 84
S K++ +L +R + + +E+ K R +H + E+A+ K+ + +
Sbjct: 607 SHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKE 666
Query: 85 LNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNVTVAPDSSQGPI 144
L + RL++ +E D +++DVL ++ + + + L + ++ + Q
Sbjct: 667 KELRQLRLAV-RERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLK 725
Query: 145 VVNQDPITQ-SIFNESVIEP--QALNDVDGEEEGTVNSQ-----SGESENENELDNSLNS 196
+ ++ ES+I+ +L+D + E E + G+SE EL L
Sbjct: 726 EEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQR 785
Query: 197 QSNTNTDRFLQQLTEENFELISKLWTDIQ---QKIATQSQITPPGTPSSALSSGEQRAAL 253
+ +R LQ L + + + + +IQ Q ++T+ Q + Q AA
Sbjct: 786 K-----ERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQES-------------QAAAE 827
Query: 254 NATNAVKRLQTRLQP-EESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKN 312
A+ + LQ + DS + N + + + ++ + ++ P ++
Sbjct: 828 KLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRD 887
Query: 313 ISSGSTTSAD--LPNRTNSNLDVLKHMIHEVEHEMEEYE------RWTGREVKGLQSSQG 364
S+ T D +P T +LD + + E+ + EE E R + E+ LQS
Sbjct: 888 DSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMA 947
Query: 365 LTGFTLSL----VSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILR 420
+ L + + SL R IQ+++++ Q++ V + ++ LT E+L
Sbjct: 948 VQEEELQVQAADMESLTR--------NIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLL 999
Query: 421 LREENAATQARLQQYMVTTDEQLISLTHAI 450
LRE+ A+ +++ Q+ +QL+ + +
Sbjct: 1000 LREKVASVESQGQEISGNRRQQLLLMLEGL 1029
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 41.2 bits (95), Expect = 0.004
Identities = 88/450 (19%), Positives = 187/450 (41%), Gaps = 53/450 (11%)
Query: 27 SVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQ--EKALKRKWRKQKPET 84
S K++ +L +R + + +E+ K R +H + E+A+ K+ + +
Sbjct: 444 SHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKE 503
Query: 85 LNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNVTVAPDSSQGPI 144
L + RL++ +E D +++DVL ++ + + + L + ++ + Q
Sbjct: 504 KELRQLRLAV-RERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLK 562
Query: 145 VVNQDPITQ-SIFNESVIEP--QALNDVDGEEEGTVNSQ-----SGESENENELDNSLNS 196
+ ++ ES+I+ +L+D + E E + G+SE EL L
Sbjct: 563 EEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQR 622
Query: 197 QSNTNTDRFLQQLTEENFELISKLWTDIQ---QKIATQSQITPPGTPSSALSSGEQRAAL 253
+ +R LQ L + + + + +IQ Q ++T+ Q + Q AA
Sbjct: 623 K-----ERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQES-------------QAAAE 664
Query: 254 NATNAVKRLQTRLQP-EESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKN 312
A+ + LQ + DS + N + + + ++ + ++ P ++
Sbjct: 665 KLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRD 724
Query: 313 ISSGSTTSAD--LPNRTNSNLDVLKHMIHEVEHEMEEYE------RWTGREVKGLQSSQG 364
S+ T D +P T +LD + + E+ + EE E R + E+ LQS
Sbjct: 725 DSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMA 784
Query: 365 LTGFTLSL----VSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILR 420
+ L + + SL R IQ+++++ Q++ V + ++ LT E+L
Sbjct: 785 VQEEELQVQAADMESLTR--------NIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLL 836
Query: 421 LREENAATQARLQQYMVTTDEQLISLTHAI 450
LRE+ A+ +++ Q+ +QL+ + +
Sbjct: 837 LREKVASVESQGQEISGNRRQQLLLMLEGL 866
Score = 31.6 bits (70), Expect = 3.3
Identities = 60/280 (21%), Positives = 115/280 (41%), Gaps = 37/280 (13%)
Query: 160 VIEPQALN-----DVDGEEEGTVNSQSGESENENELDNSLNS----QSNTNTDRFLQQLT 210
++EP L DV ++G+V+ + +L++ + + R L+Q
Sbjct: 1799 ILEPGYLGSSGKWDVMRPQKGSVSGDLSSGSSVYQLNSKPTGADLLEEHLGEIRNLRQRL 1858
Query: 211 EENFELISKLWTDIQQKIATQSQITPPGTPSSALSSG-EQRAALNATNAV-----KRLQT 264
EE+ + +L ++ ++ + ++ G+ S+ S G E L N V +RLQ
Sbjct: 1859 EESICINDRLREQLEHRLTSTAR--GRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQA 1916
Query: 265 RLQPEESTETLDSSYVVGHVLNSRKQKQLLNK------VKRKPNLHALSKPKKNISSGST 318
+L + ++ + +L+SR Q L K V+R+ L L + ++ +
Sbjct: 1917 QLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFRE 1976
Query: 319 TSADLP---NRTNSNLDVLKHMIHE-------VEHEMEEYERWTGREVKGLQSSQGLTGF 368
L +R L +L+ E ++ E++ YE G KGL++
Sbjct: 1977 ERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKAYSLDACH 2036
Query: 369 TLSLVSSLCRLVRYLKESEIQLRKEVE----TRQQLEQVL 404
+ L S L LV ++ QL + ++ R QL+Q L
Sbjct: 2037 QIPLSSDLSHLVAEVRALRGQLEQSIQGNNCLRLQLQQQL 2076
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 40.8 bits (94), Expect = 0.005
Identities = 66/299 (22%), Positives = 135/299 (45%), Gaps = 41/299 (13%)
Query: 185 ENENELDNSLNSQSNTNTDRF-LQQLTEENFELISKLWTDIQQKIATQSQITPP-GTPSS 242
E+++EL++S + +T+ F L+ EE+ E + + + S +T G+
Sbjct: 1462 ESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGK 1521
Query: 243 ALSSGEQ-RAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQ-KQLLNKVKRK 300
+ E+ R L A ++++ + EE+ +L+ + G +L ++ + Q+ +++RK
Sbjct: 1522 TIHELEKVRKQLEA----EKMELQSALEEAEASLE--HEEGKILRAQLEFNQIKAEIERK 1575
Query: 301 --PNLHALSKPKKN---ISSGSTTSADLPNRT-NSNLDVLKHM---IHEVEHEMEEYERW 351
+ + K+N + TS D R+ N L V K M ++E+E ++ R
Sbjct: 1576 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRM 1635
Query: 352 TGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELI 411
K ++S Q L LK+++IQL V L++ +
Sbjct: 1636 AAEAQKQVKSLQSL-----------------LKDTQIQLDDAVRANDDLKENIAIVERRN 1678
Query: 412 DALTAEILRLR---EENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASES 467
+ L AE+ LR E+ ++ +Q ++ T E+ + L H+ +N +IN ++++ A S
Sbjct: 1679 NLLQAELEELRAVVEQTERSRKLAEQELIETSER-VQLLHS-QNTSLINQKKKMDADLS 1735
>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
Length = 1113
Score = 40.8 bits (94), Expect = 0.005
Identities = 85/448 (18%), Positives = 174/448 (38%), Gaps = 56/448 (12%)
Query: 28 VKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQEKALKRKW-----RKQKP 82
V +E+ + V DL +L + + + ++ + +LQE ++R R++
Sbjct: 79 VLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQ 138
Query: 83 ETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRR---TGFPNVTVAPDS 139
+L + + + E+ + + +D+L+ S+ I +++ ++ V +
Sbjct: 139 SQEDLRNQLQNTVHELEAAKCLKEDMLKDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEE 198
Query: 140 SQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQSGESENENELDNSLNSQSN 199
+ G + D ++ F A++ + E + ++ G + +L S+S
Sbjct: 199 ASGKKICEHDSMSTLHFRSL---GSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQ 255
Query: 200 TNTDRFLQQLTEENFELISKLWTDI-----------QQKIATQSQITPPGTPSSALSSGE 248
+ LQQ + +LIS+ +I Q + QSQ+ + +S
Sbjct: 256 NKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMY 315
Query: 249 QRAALNATNAVKRLQTRLQP-----EESTETLDSSYVVGHV------------------L 285
R + + V +L++ L+ E+ TE L+ V+ + L
Sbjct: 316 MRQLSDLESTVSQLRSELREAKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNL 375
Query: 286 NSRKQKQLLNKVKRKPNLHALSKPKKNI---SSGSTTSADLPNRT--NSNLDV------L 334
+ + QK L + KR+ L + K + +G++ + D R N N++V L
Sbjct: 376 DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLEALL 435
Query: 335 KHMIHEVEHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEV 394
K + E + +ME + + L+ LT S L ++V L ++ L
Sbjct: 436 KALKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSE 495
Query: 395 ETRQQLEQVLGDHRELIDALTAEILRLR 422
T L L + I+A AEI +LR
Sbjct: 496 RTISDLTTSLQEKERAIEATNAEITKLR 523
Score = 33.1 bits (74), Expect = 1.1
Identities = 42/209 (20%), Positives = 88/209 (42%), Gaps = 11/209 (5%)
Query: 374 SSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELI--------DALTAEILRLREEN 425
S R V+ +K+ QL EV+T + L + E++ + + +L+ +
Sbjct: 642 SERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQL 701
Query: 426 AATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGATGRRVMDSPERPVVNA 485
+ Q+ L+Q T S HA+K + + + + A ++ E + NA
Sbjct: 702 KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFL-EEAMTNA 760
Query: 486 NVSVPLMFREEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPAVLLTPPRQKSNL 545
N + +EE ++ QE L ++ + + ++ + E + K++L
Sbjct: 761 NKEKHFL-KEEKSKLSQE-LSTVATEKNKMAGELEVLRSQERRLKEKVTNMEVALDKASL 818
Query: 546 KFSPLQDVLRRTVQTRPAPRLPPTVEIIE 574
+F+ QD+++R Q +L T++I E
Sbjct: 819 QFAECQDIIQRQEQESVRLKLQHTLDIKE 847
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.4 bits (93), Expect = 0.007
Identities = 57/270 (21%), Positives = 112/270 (41%), Gaps = 47/270 (17%)
Query: 185 ENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSAL 244
E + + + + +S T + QL E N E ++ L D + AT+ + PP L
Sbjct: 2241 EEKEQAEIQIKEESKTAVEMLQNQLKELN-EAVAALCGDQEIMKATEQSLDPPIEEEHQL 2299
Query: 245 SSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLH 304
N++++L+ RL+ +E +KQ +L ++K +
Sbjct: 2300 R-----------NSIEKLRARLEADE-----------------KKQLCVLQQLKESEHHA 2331
Query: 305 ALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQSSQG 364
L K + A RTN +H E E+ E E + ++G+ +Q
Sbjct: 2332 DLLKGRVENLERELEIA----RTNQ-----EHAALEAENSKGEVETLKAK-IEGM--TQS 2379
Query: 365 LTGFTLSLVSSLCRLVRYLKESEI-QLRKEVETRQQLEQVLGDHRELIDALTAEILRLRE 423
L G L +V+ +R KE+ +L+KE E +LE + ++ E ++++E
Sbjct: 2380 LRGLELDVVT-----IRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Query: 424 ENAATQARLQQYMVTTDEQLISLTHAIKNC 453
+++ LQ + +E++ +L + + C
Sbjct: 2435 KSSTAMEMLQTQLKELNERVAALHNDQEAC 2464
Score = 33.5 bits (75), Expect = 0.86
Identities = 46/247 (18%), Positives = 107/247 (43%), Gaps = 21/247 (8%)
Query: 189 ELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSALSSGE 248
EL+N + +Q N + +++ L + + A ++ + G + LSS +
Sbjct: 2053 ELENQI-AQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQ 2111
Query: 249 QRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSK 308
+ +++L+ R++ +E + H+ K+++ N + + +
Sbjct: 2112 EEVH-QLRRGIEKLRVRIEADEKKQL--------HIAEKLKERERENDSLKDKVENLERE 2162
Query: 309 PKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYER-----WTGRE--VKGLQS 361
+ + + D N + + ++ LK I E+ ++ +E + +E K +Q
Sbjct: 2163 LQMSEENQELVILDAEN-SKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQE 2221
Query: 362 SQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETR-QQLEQVLGDHRELIDALTA--EI 418
QG L+SS L+ +++EIQ+++E +T + L+ L + E + AL EI
Sbjct: 2222 KQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEI 2281
Query: 419 LRLREEN 425
++ E++
Sbjct: 2282 MKATEQS 2288
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 40.0 bits (92), Expect = 0.009
Identities = 81/414 (19%), Positives = 166/414 (40%), Gaps = 61/414 (14%)
Query: 67 ELQEKALKRKWRKQKPETLN---LEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELF 123
E++E+ K K +KPE + L R ++ K ++ +L + AA +E
Sbjct: 1694 EVEEQTFKEKELDRKPEDVPPEILSNERYALQKA----NNRLLKILLEVVKTTAAVEETI 1749
Query: 124 PRRRTGFPNVTVAPDSSQGPIVVNQ-DPITQSIFNE--SVIEPQALNDVDGEE--EGTVN 178
R G + + SS I ++ + +S +E + + +++ G + +N
Sbjct: 1750 GRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDIN 1809
Query: 179 SQSGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPG 238
S +E EL L T+ + EN EL+ + + +Q + +
Sbjct: 1810 MWSKVTEEGTELSQRLVRSGFAGTE-----IDPENEELMLNISSRLQAAVEKLLEAI--- 1861
Query: 239 TPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLN--SRKQKQLLNK 296
S SS + A + T ++ ++ Q +E+TE+L + L+ SR ++QL +
Sbjct: 1862 ---SETSSQLEHAKVTQTELMR--ESFRQKQEATESLKCQEELRERLHEESRAREQLAVE 1916
Query: 297 VKRKPN-LHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHE---MEEYERWT 352
+ + + + K D+ +R L + + E+E E ++E
Sbjct: 1917 LSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELL 1976
Query: 353 GREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELID 412
R+ + +++ G L L+E+E +++++E + Q E+V D ++ +
Sbjct: 1977 SRQKEAMKAEAGPVEQQL------------LQETEKLMKEKLEVQCQAEKVRDDLQKQVK 2024
Query: 413 AL------------------TAEILRLREENAATQARLQQYMVTTDEQLISLTH 448
AL E++ LR++N A + +L++ DEQ I H
Sbjct: 2025 ALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREH 2078
Score = 33.5 bits (75), Expect = 0.86
Identities = 61/287 (21%), Positives = 109/287 (37%), Gaps = 30/287 (10%)
Query: 79 KQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNVTVAPD 138
K K E L K KEIL D+ E D ++ ++E+F + +T ++ +
Sbjct: 1509 KFKEEFKPLSKELGEHGKEILLSNSDPHDIPESKDCVLTISEEMFSKDKTFIVRQSIHDE 1568
Query: 139 SSQGPIVVNQDPITQSIFNESVIE---PQALNDVDGEEEGTV---NSQSGESENENELDN 192
S V + D Q + NE +E + + ++ T + + E + E
Sbjct: 1569 IS----VSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQMERQREDQE 1624
Query: 193 SLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPG---------TPSSA 243
L + + Q+ + +N L+S+ + +++ Q++ G S+
Sbjct: 1625 QLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRNSSTQ 1684
Query: 244 LSSGEQRAALNATNAVKRLQTRLQPEE-STETLDSSYVVGHVLNSRKQKQLLNKVKRKPN 302
+G + K + +PE+ E L + N+R K LL VK
Sbjct: 1685 TQNGNENQGEVEEQTFKEKELDRKPEDVPPEILSNERYALQKANNRLLKILLEVVKTTAA 1744
Query: 303 L------HALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEH 343
+ H L + SS S +SA L R+ + V K +HE EH
Sbjct: 1745 VEETIGRHVLGILDR--SSKSQSSASLIWRSEAEASV-KSCVHE-EH 1787
Score = 32.0 bits (71), Expect = 2.5
Identities = 69/336 (20%), Positives = 141/336 (41%), Gaps = 27/336 (8%)
Query: 20 KVKKKKTSVKQEWDNTVT---DLTVHRATPEDLVRRHEIHKSKNRALVHWELQEKALKRK 76
++ +K +++ E DN +T L + + +DL + KS+ L ELQ++ +
Sbjct: 673 EMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILR 732
Query: 77 WRKQKPETLNLEKRRLSIMKEILSDQYQMQ--DVLEKSDHLIAAAKELFPRRRTGFPNVT 134
+++ TL E + L + E+L Q + + D+ EK L A L ++T +
Sbjct: 733 QEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLK 792
Query: 135 VAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQSGESENENELDNSL 194
+ SQ ++ D I +S +SV E + ++ EE + Q + E E +
Sbjct: 793 IHTPVSQEERLIFLDSI-KSKSKDSVWEKEI--EILIEENEDLKQQCIQLNEEIEKQRNT 849
Query: 195 NSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSALSSGEQRAALN 254
S + N + Q+L EE + + K+ D++ + Q + AL+ +N
Sbjct: 850 FSFAEKNFEVNYQELQEE-YACLLKVKDDLED--SKNKQELEYKSKLKALNEELHLQRIN 906
Query: 255 ATNAVKRLQTRLQPEEST---ETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKK 311
T ++++ + E+ T ETL+ VV + +L+ K L + K
Sbjct: 907 PTTV--KMKSSVFDEDKTFVAETLEMGEVV-----EKDTTELMEK------LEVTKREKL 953
Query: 312 NISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEE 347
+S + ++ + + + L + ++ E E+
Sbjct: 954 ELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQ 989
Score = 30.0 bits (66), Expect = 9.5
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 6/128 (4%)
Query: 289 KQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEY 348
+QKQLLN+ ++K + + +S + +L S ++ M ++ E E +
Sbjct: 3265 QQKQLLNESQQKIESQRMLYDAQ-LSEEQGRNLELQVLLESEKVRIREMSSTLDRERELH 3323
Query: 349 ERW-----TGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQV 403
+ TG+ L S L L R+V L E+E ++TRQQ+E+
Sbjct: 3324 AQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKD 3383
Query: 404 LGDHRELI 411
HR+ +
Sbjct: 3384 RQVHRKTL 3391
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 40.0 bits (92), Expect = 0.009
Identities = 81/414 (19%), Positives = 166/414 (40%), Gaps = 61/414 (14%)
Query: 67 ELQEKALKRKWRKQKPETLN---LEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELF 123
E++E+ K K +KPE + L R ++ K ++ +L + AA +E
Sbjct: 1694 EVEEQTFKEKELDRKPEDVPPEILSNERYALQKA----NNRLLKILLEVVKTTAAVEETI 1749
Query: 124 PRRRTGFPNVTVAPDSSQGPIVVNQ-DPITQSIFNE--SVIEPQALNDVDGEE--EGTVN 178
R G + + SS I ++ + +S +E + + +++ G + +N
Sbjct: 1750 GRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDIN 1809
Query: 179 SQSGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPG 238
S +E EL L T+ + EN EL+ + + +Q + +
Sbjct: 1810 MWSKVTEEGTELSQRLVRSGFAGTE-----IDPENEELMLNISSRLQAAVEKLLEAI--- 1861
Query: 239 TPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLN--SRKQKQLLNK 296
S SS + A + T ++ ++ Q +E+TE+L + L+ SR ++QL +
Sbjct: 1862 ---SETSSQLEHAKVTQTELMR--ESFRQKQEATESLKCQEELRERLHEESRAREQLAVE 1916
Query: 297 VKRKPN-LHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHE---MEEYERWT 352
+ + + + K D+ +R L + + E+E E ++E
Sbjct: 1917 LSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELL 1976
Query: 353 GREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELID 412
R+ + +++ G L L+E+E +++++E + Q E+V D ++ +
Sbjct: 1977 SRQKEAMKAEAGPVEQQL------------LQETEKLMKEKLEVQCQAEKVRDDLQKQVK 2024
Query: 413 AL------------------TAEILRLREENAATQARLQQYMVTTDEQLISLTH 448
AL E++ LR++N A + +L++ DEQ I H
Sbjct: 2025 ALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREH 2078
Score = 33.5 bits (75), Expect = 0.86
Identities = 61/287 (21%), Positives = 109/287 (37%), Gaps = 30/287 (10%)
Query: 79 KQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNVTVAPD 138
K K E L K KEIL D+ E D ++ ++E+F + +T ++ +
Sbjct: 1509 KFKEEFKPLSKELGEHGKEILLSNSDPHDIPESKDCVLTISEEMFSKDKTFIVRQSIHDE 1568
Query: 139 SSQGPIVVNQDPITQSIFNESVIE---PQALNDVDGEEEGTV---NSQSGESENENELDN 192
S V + D Q + NE +E + + ++ T + + E + E
Sbjct: 1569 IS----VSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQMERQREDQE 1624
Query: 193 SLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPG---------TPSSA 243
L + + Q+ + +N L+S+ + +++ Q++ G S+
Sbjct: 1625 QLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRNSSTQ 1684
Query: 244 LSSGEQRAALNATNAVKRLQTRLQPEE-STETLDSSYVVGHVLNSRKQKQLLNKVKRKPN 302
+G + K + +PE+ E L + N+R K LL VK
Sbjct: 1685 TQNGNENQGEVEEQTFKEKELDRKPEDVPPEILSNERYALQKANNRLLKILLEVVKTTAA 1744
Query: 303 L------HALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEH 343
+ H L + SS S +SA L R+ + V K +HE EH
Sbjct: 1745 VEETIGRHVLGILDR--SSKSQSSASLIWRSEAEASV-KSCVHE-EH 1787
Score = 32.0 bits (71), Expect = 2.5
Identities = 69/336 (20%), Positives = 141/336 (41%), Gaps = 27/336 (8%)
Query: 20 KVKKKKTSVKQEWDNTVT---DLTVHRATPEDLVRRHEIHKSKNRALVHWELQEKALKRK 76
++ +K +++ E DN +T L + + +DL + KS+ L ELQ++ +
Sbjct: 673 EMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILR 732
Query: 77 WRKQKPETLNLEKRRLSIMKEILSDQYQMQ--DVLEKSDHLIAAAKELFPRRRTGFPNVT 134
+++ TL E + L + E+L Q + + D+ EK L A L ++T +
Sbjct: 733 QEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLK 792
Query: 135 VAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQSGESENENELDNSL 194
+ SQ ++ D I +S +SV E + ++ EE + Q + E E +
Sbjct: 793 IHTPVSQEERLIFLDSI-KSKSKDSVWEKEI--EILIEENEDLKQQCIQLNEEIEKQRNT 849
Query: 195 NSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSALSSGEQRAALN 254
S + N + Q+L EE + + K+ D++ + Q + AL+ +N
Sbjct: 850 FSFAEKNFEVNYQELQEE-YACLLKVKDDLED--SKNKQELEYKSKLKALNEELHLQRIN 906
Query: 255 ATNAVKRLQTRLQPEEST---ETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKK 311
T ++++ + E+ T ETL+ VV + +L+ K L + K
Sbjct: 907 PTTV--KMKSSVFDEDKTFVAETLEMGEVV-----EKDTTELMEK------LEVTKREKL 953
Query: 312 NISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEE 347
+S + ++ + + + L + ++ E E+
Sbjct: 954 ELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQ 989
Score = 30.0 bits (66), Expect = 9.5
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 6/128 (4%)
Query: 289 KQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEY 348
+QKQLLN+ ++K + + +S + +L S ++ M ++ E E +
Sbjct: 3257 QQKQLLNESQQKIESQRMLYDAQ-LSEEQGRNLELQVLLESEKVRIREMSSTLDRERELH 3315
Query: 349 ERW-----TGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQV 403
+ TG+ L S L L R+V L E+E ++TRQQ+E+
Sbjct: 3316 AQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKD 3375
Query: 404 LGDHRELI 411
HR+ +
Sbjct: 3376 RQVHRKTL 3383
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 40.0 bits (92), Expect = 0.009
Identities = 57/294 (19%), Positives = 111/294 (37%), Gaps = 45/294 (15%)
Query: 168 DVDGEEEGTVNSQSGESENENELDNSLNSQSN-TNTDRFLQQLTEENFELISKLWTDIQQ 226
++ +E+ ++ + + ENEL S T LQ+ + EL ++ +++
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA-EEMRV 911
Query: 227 KIATQSQITPP--GTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHV 284
++A + Q + L E R K Q L EE E +++
Sbjct: 912 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA------ 965
Query: 285 LNSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHE 344
+QK L KV + + K + D N+ + +L+ I ++
Sbjct: 966 ----RQKLQLEKVTAEAKI-------KKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 345 MEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQV- 403
+ E E K + + + E E++L+KE ++RQ+LE++
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESM-----------------ISELEVRLKKEEKSRQELEKLK 1057
Query: 404 ------LGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQLISLTHAIK 451
D E I L A+I L+ + A + LQ + D+++ +A+K
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1111
Score = 35.0 bits (79), Expect = 0.30
Identities = 94/462 (20%), Positives = 172/462 (37%), Gaps = 71/462 (15%)
Query: 25 KTSVKQEWDNTVT----------DLTVHRATPEDLVRRHEIHKSKNR-----ALVHWELQ 69
KT ++ D+T T ++TV + ++ R HE + R A+ Q
Sbjct: 1152 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1211
Query: 70 EKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTG 129
+ KR LEK + E+ Q+V K L A +EL +
Sbjct: 1212 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK---- 1267
Query: 130 FPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEE---EGTVNSQSGESEN 186
D + +N + NE LN+ +G+ V S S + ++
Sbjct: 1268 ------CSDGERARAELNDK--VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319
Query: 187 ENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSS---- 242
EL ++ N L+QL EE L +L +++ K + I+ S
Sbjct: 1320 TQELLQE-ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 243 ----------ALSSGEQRAALNATNAVKRLQTR---LQPEESTETLDSSYVVGHVLNSRK 289
AL G++R N ++ + + E T+ + V++
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 290 QKQLLNKVKRKP-NLHALSKPKKNISS-----GSTTSADLPNRTNSNLDVLKHMIH--EV 341
Q+QL++ +++K L +KNISS A+ + L + + + E
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 342 EHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEV-ETRQQL 400
+ E+E + E++ L SS+ G + V L++S+ L ++ E + QL
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVG----------KNVHELEKSKRALETQMEEMKTQL 1548
Query: 401 EQVLGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQ 442
E++ + + DA LRL A + + ++ + DEQ
Sbjct: 1549 EELEDELQATEDAK----LRLEVNMQALKGQFERDLQARDEQ 1586
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 40.0 bits (92), Expect = 0.009
Identities = 57/294 (19%), Positives = 111/294 (37%), Gaps = 45/294 (15%)
Query: 168 DVDGEEEGTVNSQSGESENENELDNSLNSQSN-TNTDRFLQQLTEENFELISKLWTDIQQ 226
++ +E+ ++ + + ENEL S T LQ+ + EL ++ +++
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA-EEMRV 918
Query: 227 KIATQSQITPP--GTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHV 284
++A + Q + L E R K Q L EE E +++
Sbjct: 919 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA------ 972
Query: 285 LNSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHE 344
+QK L KV + + K + D N+ + +L+ I ++
Sbjct: 973 ----RQKLQLEKVTAEAKI-------KKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1021
Query: 345 MEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQV- 403
+ E E K + + + E E++L+KE ++RQ+LE++
Sbjct: 1022 LAEEEEKAKNLTKLKNKHESM-----------------ISELEVRLKKEEKSRQELEKLK 1064
Query: 404 ------LGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQLISLTHAIK 451
D E I L A+I L+ + A + LQ + D+++ +A+K
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1118
Score = 35.0 bits (79), Expect = 0.30
Identities = 94/462 (20%), Positives = 172/462 (37%), Gaps = 71/462 (15%)
Query: 25 KTSVKQEWDNTVT----------DLTVHRATPEDLVRRHEIHKSKNR-----ALVHWELQ 69
KT ++ D+T T ++TV + ++ R HE + R A+ Q
Sbjct: 1159 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1218
Query: 70 EKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTG 129
+ KR LEK + E+ Q+V K L A +EL +
Sbjct: 1219 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK---- 1274
Query: 130 FPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEE---EGTVNSQSGESEN 186
D + +N + NE LN+ +G+ V S S + ++
Sbjct: 1275 ------CSDGERARAELNDK--VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1326
Query: 187 ENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSS---- 242
EL ++ N L+QL EE L +L +++ K + I+ S
Sbjct: 1327 TQELLQE-ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 243 ----------ALSSGEQRAALNATNAVKRLQTR---LQPEESTETLDSSYVVGHVLNSRK 289
AL G++R N ++ + + E T+ + V++
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Query: 290 QKQLLNKVKRKP-NLHALSKPKKNISS-----GSTTSADLPNRTNSNLDVLKHMIH--EV 341
Q+QL++ +++K L +KNISS A+ + L + + + E
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1505
Query: 342 EHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEV-ETRQQL 400
+ E+E + E++ L SS+ G + V L++S+ L ++ E + QL
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVG----------KNVHELEKSKRALETQMEEMKTQL 1555
Query: 401 EQVLGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQ 442
E++ + + DA LRL A + + ++ + DEQ
Sbjct: 1556 EELEDELQATEDAK----LRLEVNMQALKGQFERDLQARDEQ 1593
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 40.0 bits (92), Expect = 0.009
Identities = 57/294 (19%), Positives = 111/294 (37%), Gaps = 45/294 (15%)
Query: 168 DVDGEEEGTVNSQSGESENENELDNSLNSQSN-TNTDRFLQQLTEENFELISKLWTDIQQ 226
++ +E+ ++ + + ENEL S T LQ+ + EL ++ +++
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA-EEMRV 918
Query: 227 KIATQSQITPP--GTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHV 284
++A + Q + L E R K Q L EE E +++
Sbjct: 919 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA------ 972
Query: 285 LNSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHE 344
+QK L KV + + K + D N+ + +L+ I ++
Sbjct: 973 ----RQKLQLEKVTAEAKI-------KKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1021
Query: 345 MEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQV- 403
+ E E K + + + E E++L+KE ++RQ+LE++
Sbjct: 1022 LAEEEEKAKNLTKLKNKHESM-----------------ISELEVRLKKEEKSRQELEKLK 1064
Query: 404 ------LGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQLISLTHAIK 451
D E I L A+I L+ + A + LQ + D+++ +A+K
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1118
Score = 35.0 bits (79), Expect = 0.30
Identities = 94/462 (20%), Positives = 172/462 (37%), Gaps = 71/462 (15%)
Query: 25 KTSVKQEWDNTVT----------DLTVHRATPEDLVRRHEIHKSKNR-----ALVHWELQ 69
KT ++ D+T T ++TV + ++ R HE + R A+ Q
Sbjct: 1159 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1218
Query: 70 EKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTG 129
+ KR LEK + E+ Q+V K L A +EL +
Sbjct: 1219 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK---- 1274
Query: 130 FPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEE---EGTVNSQSGESEN 186
D + +N + NE LN+ +G+ V S S + ++
Sbjct: 1275 ------CSDGERARAELNDK--VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1326
Query: 187 ENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSS---- 242
EL ++ N L+QL EE L +L +++ K + I+ S
Sbjct: 1327 TQELLQE-ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 243 ----------ALSSGEQRAALNATNAVKRLQTR---LQPEESTETLDSSYVVGHVLNSRK 289
AL G++R N ++ + + E T+ + V++
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Query: 290 QKQLLNKVKRKP-NLHALSKPKKNISS-----GSTTSADLPNRTNSNLDVLKHMIH--EV 341
Q+QL++ +++K L +KNISS A+ + L + + + E
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1505
Query: 342 EHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEV-ETRQQL 400
+ E+E + E++ L SS+ G + V L++S+ L ++ E + QL
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVG----------KNVHELEKSKRALETQMEEMKTQL 1555
Query: 401 EQVLGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQ 442
E++ + + DA LRL A + + ++ + DEQ
Sbjct: 1556 EELEDELQATEDAK----LRLEVNMQALKGQFERDLQARDEQ 1593
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 40.0 bits (92), Expect = 0.009
Identities = 57/294 (19%), Positives = 111/294 (37%), Gaps = 45/294 (15%)
Query: 168 DVDGEEEGTVNSQSGESENENELDNSLNSQSN-TNTDRFLQQLTEENFELISKLWTDIQQ 226
++ +E+ ++ + + ENEL S T LQ+ + EL ++ +++
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA-EEMRV 911
Query: 227 KIATQSQITPP--GTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHV 284
++A + Q + L E R K Q L EE E +++
Sbjct: 912 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA------ 965
Query: 285 LNSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHE 344
+QK L KV + + K + D N+ + +L+ I ++
Sbjct: 966 ----RQKLQLEKVTAEAKI-------KKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 345 MEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQV- 403
+ E E K + + + E E++L+KE ++RQ+LE++
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESM-----------------ISELEVRLKKEEKSRQELEKLK 1057
Query: 404 ------LGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQLISLTHAIK 451
D E I L A+I L+ + A + LQ + D+++ +A+K
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1111
Score = 35.0 bits (79), Expect = 0.30
Identities = 94/462 (20%), Positives = 172/462 (37%), Gaps = 71/462 (15%)
Query: 25 KTSVKQEWDNTVT----------DLTVHRATPEDLVRRHEIHKSKNR-----ALVHWELQ 69
KT ++ D+T T ++TV + ++ R HE + R A+ Q
Sbjct: 1152 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1211
Query: 70 EKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTG 129
+ KR LEK + E+ Q+V K L A +EL +
Sbjct: 1212 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK---- 1267
Query: 130 FPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEE---EGTVNSQSGESEN 186
D + +N + NE LN+ +G+ V S S + ++
Sbjct: 1268 ------CSDGERARAELNDK--VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319
Query: 187 ENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSS---- 242
EL ++ N L+QL EE L +L +++ K + I+ S
Sbjct: 1320 TQELLQE-ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 243 ----------ALSSGEQRAALNATNAVKRLQTR---LQPEESTETLDSSYVVGHVLNSRK 289
AL G++R N ++ + + E T+ + V++
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 290 QKQLLNKVKRKP-NLHALSKPKKNISS-----GSTTSADLPNRTNSNLDVLKHMIH--EV 341
Q+QL++ +++K L +KNISS A+ + L + + + E
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 342 EHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEV-ETRQQL 400
+ E+E + E++ L SS+ G + V L++S+ L ++ E + QL
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVG----------KNVHELEKSKRALETQMEEMKTQL 1548
Query: 401 EQVLGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQ 442
E++ + + DA LRL A + + ++ + DEQ
Sbjct: 1549 EELEDELQATEDAK----LRLEVNMQALKGQFERDLQARDEQ 1586
>gi|114842396 ankyrin-repeat and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 763
Score = 38.5 bits (88), Expect = 0.027
Identities = 44/196 (22%), Positives = 76/196 (38%), Gaps = 21/196 (10%)
Query: 608 HMGEDLENKTQAPFVNLSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTNESLIQ--R 665
H N + + NLS+ L SHS+ ++ T ++ L + + NE++ +
Sbjct: 87 HSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVE 146
Query: 666 KDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTSTFPVAQSLTPG 725
+ M + L Q + + +N +GL L+ + MT+ P+A+ L
Sbjct: 147 QQDMDAVQILLYQYTPEELDLNT------PNSEGLTPLD----IAIMTNNVPIARILLRT 196
Query: 726 ---------SMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSPPMSPVQLPLRAWTEG 776
S+E R LN EA+ ++ +L Q + G L QL W
Sbjct: 197 GARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQLKAWEWRYR 256
Query: 777 AKRTIEVSIPGAEAPE 792
R ++ A APE
Sbjct: 257 LYRRMKTGFEHARAPE 272
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 38.1 bits (87), Expect = 0.035
Identities = 49/207 (23%), Positives = 83/207 (40%), Gaps = 25/207 (12%)
Query: 124 PRRRTGFPNVTVAPDSSQGPIVVNQDPITQSIFNE---SVIEPQALNDVDGEEEGTVNSQ 180
P G P+ APD++ P + DP T+ + S I A D +EG +N Q
Sbjct: 25 PEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNGQLSTINGVAEQDELSLQEGDLNGQ 84
Query: 181 SGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTP 240
G + +LNSQ + ++ + + E +SK D +++AT+S + T
Sbjct: 85 KGALNGQ----GALNSQEEEEV--IVTEVGQRDSEDVSK--RDSDKEMATKSAVVHDITD 136
Query: 241 SSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSY-----VVGHVLNSRKQKQLLN 295
+ E + ++ + L+ QP ES + D + VG +K K
Sbjct: 137 DGQEETPEIIEQIPSSES--NLEELTQPTES-QANDIGFKKVFKFVGFKFTVKKDK---- 189
Query: 296 KVKRKPNLHALSKPKKNISSGSTTSAD 322
KP+ L KK+ G+ + D
Sbjct: 190 --TEKPDTVQLLTVKKDEGEGAAGAGD 214
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 37.7 bits (86), Expect = 0.046
Identities = 53/228 (23%), Positives = 95/228 (41%), Gaps = 17/228 (7%)
Query: 236 PPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNS-----RKQ 290
PP + S GEQ+ + T++V R + ++ + +DS L S
Sbjct: 1011 PPVGAAYQDSPGEQKG-IKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENP 1069
Query: 291 KQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYER 350
+ +L+ L + S+P +S T ++ N +N + LK IH++E E+E Y+
Sbjct: 1070 EDVLSPTSVATYLSSKSQPSAKVSVMGTDQSESINTSNET-EYLKQKIHDLETELEGYQN 1128
Query: 351 WTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQV-LGDHRE 409
+ + K Q S+ + + L + S+ E T L QV H +
Sbjct: 1129 FIFQLQKHSQCSEAIITVLCGTEGAQDGLSKPKNGSD----GEEMTFSSLHQVRYVKHVK 1184
Query: 410 LIDALTAEILRLRE-ENAATQARLQQYMVTTDE----QLISLTHAIKN 452
++ L E++ R EN Q Q+Y + ++ QL S H ++N
Sbjct: 1185 ILGPLAPEMIDSRVLENLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQN 1232
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 37.7 bits (86), Expect = 0.046
Identities = 53/228 (23%), Positives = 95/228 (41%), Gaps = 17/228 (7%)
Query: 236 PPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNS-----RKQ 290
PP + S GEQ+ + T++V R + ++ + +DS L S
Sbjct: 1011 PPVGAAYQDSPGEQKG-IKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENP 1069
Query: 291 KQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYER 350
+ +L+ L + S+P +S T ++ N +N + LK IH++E E+E Y+
Sbjct: 1070 EDVLSPTSVATYLSSKSQPSAKVSVMGTDQSESINTSNET-EYLKQKIHDLETELEGYQN 1128
Query: 351 WTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQV-LGDHRE 409
+ + K Q S+ + + L + S+ E T L QV H +
Sbjct: 1129 FIFQLQKHSQCSEAIITVLCGTEGAQDGLSKPKNGSD----GEEMTFSSLHQVRYVKHVK 1184
Query: 410 LIDALTAEILRLRE-ENAATQARLQQYMVTTDE----QLISLTHAIKN 452
++ L E++ R EN Q Q+Y + ++ QL S H ++N
Sbjct: 1185 ILGPLAPEMIDSRVLENLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQN 1232
>gi|130980075 centromere protein J [Homo sapiens]
Length = 1338
Score = 37.7 bits (86), Expect = 0.046
Identities = 65/329 (19%), Positives = 126/329 (38%), Gaps = 48/329 (14%)
Query: 129 GFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQSGESENEN 188
G PN + DS + + V P T+ E I + + +++G + +
Sbjct: 696 GVPNSDSSTDSEE-QLDVTIKPSTED--RERGISSREDSPQVCDDKGPFKDTRTQEDKRR 752
Query: 189 ELDNSLNSQSNTNTDRFLQQLTEENFE-------LISKL-------WTDIQQKIATQSQI 234
++D L+ + ++ + ++ + + E +SK+ WTD+++ + +
Sbjct: 753 DVDLDLSDKDYSSDESIMESIKHKVSEPSRSSSLSLSKMDFDDERTWTDLEENLCNHDVV 812
Query: 235 ----TPPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQ 290
+ GTP + + E K ++ ++ P + E L S S
Sbjct: 813 LGNESTYGTPQTCYPNNEIGIL------DKTIKRKIAPVKRGEDLSKSRRSRSPPTSELM 866
Query: 291 KQLLNKVKRKP--NLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEY 348
+ +K KP + H ++ K NIS D P N+ VL+ I E+E E+E++
Sbjct: 867 MKFFPSLKPKPKSDSHLGNELKLNISQ------DQPPGDNARSQVLREKIIELETEIEKF 920
Query: 349 ERWTG--------REVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQL 400
+ RE + + + F L R+ + KE +L+KE + ++
Sbjct: 921 KAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEKY 980
Query: 401 EQVL-----GDHRELIDALTAEILRLREE 424
RE I L +I LRE+
Sbjct: 981 TTAARTFPDKKEREEIQTLKQQIADLRED 1009
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 37.7 bits (86), Expect = 0.046
Identities = 125/655 (19%), Positives = 245/655 (37%), Gaps = 66/655 (10%)
Query: 178 NSQSGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQK---IATQSQI 234
+ Q +S+N + L S+S D LQ E + + Q +
Sbjct: 248 SKQPAQSQNLSPLSGF--SRSRQTQDWVLQSFEEPRRSAQDPTMLQFKSTPDLLRDQQEA 305
Query: 235 TPPG-------TPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNS 287
PPG T L G + + V + ++QP + + V G +
Sbjct: 306 APPGSVDHMKATIYGILREGSSESETSVRRKVSLVLEKMQPLVMVSSGSTKAVAGQGELT 365
Query: 288 RKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTN--SNL-DVLKHMIHEVEHE 344
RK ++L K+ + + K +K S L +T S L ++L+ E +
Sbjct: 366 RKVEELQRKLDEE-----VKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQS 420
Query: 345 MEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVL 404
+E + +G GL + L + L + E+ L+ +ETR+ LE+VL
Sbjct: 421 NKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVL 480
Query: 405 GDHRELID-------ALTAEILRLREENAATQARL----QQYMVTTDEQLISLTHAIKNC 453
+ + + LTA L+EE A+ + QQY T++ S+ A ++
Sbjct: 481 EGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDH 540
Query: 454 PVIN-NRQEIQASESGATGRRVMDSPERPVVNANVSVPLMFREEVAEFPQEELPVKLSQV 512
V+ RQ++ A G R + ++ E S+ +E++ QE L +++ +
Sbjct: 541 AVLEAERQKMSALVRGLQ-RELEETSEE--TGHWQSMFQKNKEDLRATKQELLQLRMEKE 597
Query: 513 PDPPDNMNLAKNFPAHIFEPAVLLTPPRQKSNLKFSPLQDVLRRTVQTRPAPRLPPTVEI 572
+ + + + RQ LK +++LR + + + E+
Sbjct: 598 EMEEELGEKIEVLQRELEQARASAGDTRQVEVLK----KELLRTQEELKELQAERQSQEV 653
Query: 573 IEKEQNWE-EK---TLPIDTDIQNSSEENRLFTQRWRVSHMGEDLENKTQAPFVN----- 623
+ ++ E EK L ++ D EE L Q+ + + +D E ++A V
Sbjct: 654 AGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQK-TLQQLRQDCEEASKAKMVAEAEAT 712
Query: 624 -LSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTNESLIQRKD-IMTRIADLTLQNSA 681
L Q + ++++ +LG QQL+ L+ + + R+ D + A
Sbjct: 713 VLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEA 772
Query: 682 IKAHMNNIIEPRGEQGDGLR------ELNKQESASDMTSTFPVAQSLTPGSMEE----RI 731
K + + E+ L E +E+ + Q+L EE +
Sbjct: 773 EKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREV 832
Query: 732 AELNRQSMEARGKLL-----QLIEQQKLVGLNLSPPMSPVQLPLRAWTEGAKRTI 781
+ +E + +LL +L ++ + +G + + +Q L + E A+R +
Sbjct: 833 LRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREV 887
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 37.7 bits (86), Expect = 0.046
Identities = 107/534 (20%), Positives = 201/534 (37%), Gaps = 94/534 (17%)
Query: 261 RLQTRLQPEES------TETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKNIS 314
+LQ RL+ E E + V + +Q+Q + K+K + + A + +++ S
Sbjct: 837 QLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTE-EIAAFQRKRRSGS 895
Query: 315 SGSTTSADLPNRTNSN-----------------LDVLKHMIHEVEHEMEEYERW----TG 353
+GS S + + L+ L +H+ E + + E TG
Sbjct: 896 NGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTG 955
Query: 354 REVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDA 413
E K L+SSQ L + + S L L + L E QLR+ + Q +Q+ G+ ID+
Sbjct: 956 LESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQ--GSAQSQQQIRGE----IDS 1009
Query: 414 LTAEILRLREENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGATGRR 473
L E L ++ +L+Q + + E+ +L + I+A ++ +
Sbjct: 1010 LRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTL---------FQLDEAIEALDAAIEYKN 1060
Query: 474 VMDSPERPVVNANVSVPLMFREEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPA 533
+ + V+ A+ S L+ + E+ L KLS + L K F+
Sbjct: 1061 EAITCRQRVLRASAS--LLSQCEM------NLMAKLSYLSSSETRALLCK-----YFDKV 1107
Query: 534 VLLTPPRQKSNLKFSPLQDVLRRTVQTRPAPRLPPTVEIIEKEQNWE-EKTLPIDTDIQN 592
V L + + + FS L+ +Q RL +E+ + Q E ++ L + Q
Sbjct: 1108 VTLREEQHQQQIAFSELE------MQLEEQQRLVYWLEVALERQRLEMDRQLTLQ---QK 1158
Query: 593 SSEENRLFTQRWRVSHMGEDLEN-------------KTQAPFVNLSQPLCNSHSNTQQSR 639
E+N + H+GE L + K ++ ++Q L
Sbjct: 1159 EHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAVG 1218
Query: 640 SPTFSEELPVLGDGQQLRTNESLIQRKDIMTRIADLTLQNSAIKAHMNNIIEPR------ 693
E+ + +G+Q NE + + ++ LT + +++
Sbjct: 1219 HSRGGEKRSLCSEGRQAPGNEDELHLAPELLWLSPLTEGAPRTREETRDLVHAPLPLTWK 1278
Query: 694 -----GEQGDGLRELNKQESASDMTS-TFPVAQSLTP---GSMEERIAELNRQS 738
GE+ EL ++E+A + PV ++ P G + + EL R S
Sbjct: 1279 RSSLCGEEQGSPEELRQREAAEPLVGRVLPVGEAGLPWNFGPLSKPRRELRRAS 1332
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 37.4 bits (85), Expect = 0.060
Identities = 60/273 (21%), Positives = 111/273 (40%), Gaps = 21/273 (7%)
Query: 244 LSSGEQRAALN-ATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPN 302
LS +++A L A + +K R++ E S+ + + + K+ QL K +
Sbjct: 466 LSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKER---- 521
Query: 303 LHALSKPKKNISSGSTTSADLPNRTNSN--LDVLKHMIHEVEHEMEEYERWTGREVKGLQ 360
A K KNI +L R NS+ D+LK ++ MEE E+ + +++
Sbjct: 522 -DAAKKEIKNIKE------ELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSN 574
Query: 361 SSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILR 420
+ L + + +L + +KE E +L+ + E+V HRE I L + + R
Sbjct: 575 IIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVER 634
Query: 421 LREENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASES-GATGRRVMDSPE 479
++ Q + + +L A K ++ + SE+ A R M + E
Sbjct: 635 QEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKE 694
Query: 480 RPVVNANVSVPLMFREEVAEFPQEELPVKLSQV 512
+S L +E A QE L +++ +
Sbjct: 695 ------ELSAALEKAQEEARQQQETLAIQVGDL 721
>gi|155969714 nuclear protein, ataxia-telangiectasia locus [Homo
sapiens]
Length = 1427
Score = 36.6 bits (83), Expect = 0.10
Identities = 40/140 (28%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Query: 92 LSIMKEILSDQYQMQDVLEK--SDHLIAAAKELFPRRRTGFPNVTVAPDSSQGPIVVNQD 149
L + EI + +QD+LE+ SD A +LF +T N ++ S P+ N
Sbjct: 299 LGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDYGKTK-NNKNISQSISSQPMESNPS 357
Query: 150 PITQSIFNESVIEPQALNDVDGEEEGTVNSQSGESE--NENELDNSLNSQSNTNTDRFLQ 207
+ N +V + DG QSG+ + D+ LN+ N+N L+
Sbjct: 358 IVLADETNLAVKGSFETEESDG--------QSGQPAFCTSYQNDDPLNALKNSNNHDVLR 409
Query: 208 QLTEENFELISKLWTDIQQK 227
Q +ENF IS T IQ+K
Sbjct: 410 QEDQENFSQIS---TSIQKK 426
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 36.6 bits (83), Expect = 0.10
Identities = 47/233 (20%), Positives = 90/233 (38%), Gaps = 26/233 (11%)
Query: 542 KSNLKFSPLQ-DVLRRTVQTRPAPRLPPTVEIIEKEQNWEEKTLPIDTDIQNSSEENRLF 600
K L+ P+ DVL+ P P+L P E+ KE+N E P+ +++ + L
Sbjct: 232 KQRLRNGPMNVDVLK------PLPQLEPQAEVFTKEENPESDGEPV---VEDGTSVKTLE 282
Query: 601 TQRWRVSHMGEDLENKTQAPFVNLSQ-PLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTN 659
T + RV L+ + + Q L S Q + +EL + D
Sbjct: 283 TLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKT 342
Query: 660 ESLIQRKDIMTRIADLTLQNSAI----KAHMNNIIEPRGEQGDGLR-----------ELN 704
+ + Q +D I L + K M+ +E + E+ LR EL
Sbjct: 343 KLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELR 402
Query: 705 KQESASDMTSTFPVAQSLTPGSMEERIAELNRQSMEARGKLLQLIEQQKLVGL 757
+Q+ S+ + + ++L+ E + M+ + K ++ +++ + L
Sbjct: 403 EQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISL 455
Score = 35.8 bits (81), Expect = 0.17
Identities = 90/438 (20%), Positives = 168/438 (38%), Gaps = 73/438 (16%)
Query: 52 RHEIHKSKNRALVHWELQEKAL---------KRKWRKQKPETLNL-----EKRRLSIMKE 97
R + KS+ A +E EKAL +RK + + E + E+ R+S+ +E
Sbjct: 402 REQKEKSERAA---FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 458
Query: 98 ILSDQYQMQDVLEKSDHLIAA-----------------AKELFPRRRTGFPNVTVAPDSS 140
+ + ++ DV++KS A K+L R R + VA + S
Sbjct: 459 LSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS 518
Query: 141 QGP-IVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQSGESEN--------ENELD 191
Q + ++Q+ Q +E Q + E E + E+E E+ L+
Sbjct: 519 QSEYLKISQEKEQQESLALEELELQK-KAILTESENKLRDLQQEAETYRTRILELESSLE 577
Query: 192 NSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSALSSGEQRA 251
SL N + D + E+N +K T + +K T+ + + + + Q
Sbjct: 578 KSLQENKNQSKDLAVHLEAEKNKH--NKEITVMVEKHKTELE-SLKHQQDALWTEKLQVL 634
Query: 252 ALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKK 311
+++L+ + + E+ T D + + +K L ++ L +LS
Sbjct: 635 KQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELS 694
Query: 312 NISSGSTTSADLPNRTNSNLDVLK----HMIHEVEHEMEEYERWTGREVKGLQSSQGLTG 367
+ ++ L VLK M E+E +M+E + ++V + +
Sbjct: 695 EVLKAR-------HKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEV-- 745
Query: 368 FTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILRLREENAA 427
S+ R + LK+ QL ++ R ++ L +H+ ++ L A+I R E
Sbjct: 746 -------SIQRTEKALKDQINQLELLLKER---DKHLKEHQAHVENLEADIKRSEGELQQ 795
Query: 428 TQARL---QQYMVTTDEQ 442
A+L Q Y T EQ
Sbjct: 796 ASAKLDVFQSYQSATHEQ 813
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 36.6 bits (83), Expect = 0.10
Identities = 56/288 (19%), Positives = 119/288 (41%), Gaps = 47/288 (16%)
Query: 193 SLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSALSSGEQRAA 252
SLN+ + ++ +E F+L K T+ Q++ + + S E A
Sbjct: 350 SLNNDWEKKLHNAVAEMEQEKFDL-QKQHTENIQELLEDTNVRLNKMES------EYMAQ 402
Query: 253 LNATN-AVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKK 311
+TN +K L+ R+Q + G NS Q+Q L ++ K L ++
Sbjct: 403 TQSTNHMIKELEARVQQ-----------LTGEAENSNLQRQKL--IQEKAEL------ER 443
Query: 312 NISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQSSQGLTGFTLS 371
+ ++ R N+ H++++ E M+ + ++ L+ L+ S
Sbjct: 444 CYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKAS 503
Query: 372 -----LVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELI-----DALTAEILRL 421
L ++C+L + L+ESE+Q ++++ ++ Q+ H + I L +E+ +
Sbjct: 504 SMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKG 563
Query: 422 REENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGA 469
+E+ + ++ + +EQL +T Q +QA ++ A
Sbjct: 564 KEDTQKKIHKFEEALKEKEEQLTRVTEV----------QRLQAQQADA 601
>gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens]
Length = 253
Score = 36.2 bits (82), Expect = 0.13
Identities = 52/212 (24%), Positives = 85/212 (40%), Gaps = 30/212 (14%)
Query: 240 PSSALSSG---EQRAALNATNAVKRLQTRLQPEEST-ETLDSSYVVGHVLNSRKQKQLLN 295
P S L G E R K L+T L+ +S E + S Y R+Q L
Sbjct: 61 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKY--------REQMFRLL 112
Query: 296 KVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSN---LDVLKHMIHEVEHEMEEYERWT 352
+K + + K K+ S D+ +R S LD +H++ +H
Sbjct: 113 MASKKDDPGIIMKLKEQHSK-----IDMVHRNKSEGFFLDASRHILEAPQH--------- 158
Query: 353 GREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKE-SEIQLRKEVETRQQLEQVLGDHRELI 411
G E + L+++Q + ++ + ++R E E Q KE E QLEQ RE++
Sbjct: 159 GLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREIL 218
Query: 412 DALTAEILRLREENAATQARLQQYMVTTDEQL 443
L LR+++A+ L + +D L
Sbjct: 219 QITRESFLNLRKDDASESTSLSALVTNSDLSL 250
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 35.8 bits (81), Expect = 0.17
Identities = 66/376 (17%), Positives = 142/376 (37%), Gaps = 52/376 (13%)
Query: 67 ELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRR 126
E++ + +R + + + LE + +SI KE + ++ + + +LE + I+ A + +
Sbjct: 106 EMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEE-ISCASDQVEKY 164
Query: 127 RTGFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDV-------DGEEEGTVNS 179
+ + I+ + QS+ VI + + D+ + E+E VN
Sbjct: 165 KLDIAQLEENLKEKNDEIL----SLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNR 220
Query: 180 QSGESENENELDNSLNS-------------QSNTNTDRFLQQLTEENFELISKLWT---- 222
+EN N +L Q D LQQ E + L KL +
Sbjct: 221 NREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEE 280
Query: 223 ----------DIQQKIATQSQITPPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEEST 272
+++Q + ++ + L + A + +K L+ +L+ +E+
Sbjct: 281 MVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAE 340
Query: 273 -ETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPN------ 325
E +++ +L K ++ ++ ++ A + K +++ L N
Sbjct: 341 LEKSSAAHTQATLLLQEKYDSMVQSLE---DVTAQFESYKALTASEIEDLKLENSSLQEK 397
Query: 326 --RTNSNLDVLKHMIHEVEHEMEEYERWT-GREVKGLQSSQGLTGFTLSLVSSLCRLVRY 382
+ N + ++H I E +EY R + K + T+S + + L
Sbjct: 398 AAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQ 457
Query: 383 LKESEIQLRKEVETRQ 398
LK+ E RK++E +
Sbjct: 458 LKQQEEDFRKQLEDEE 473
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 35.8 bits (81), Expect = 0.17
Identities = 66/376 (17%), Positives = 142/376 (37%), Gaps = 52/376 (13%)
Query: 67 ELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRR 126
E++ + +R + + + LE + +SI KE + ++ + + +LE + I+ A + +
Sbjct: 193 EMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEE-ISCASDQVEKY 251
Query: 127 RTGFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDV-------DGEEEGTVNS 179
+ + I+ + QS+ VI + + D+ + E+E VN
Sbjct: 252 KLDIAQLEENLKEKNDEIL----SLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNR 307
Query: 180 QSGESENENELDNSLNS-------------QSNTNTDRFLQQLTEENFELISKLWT---- 222
+EN N +L Q D LQQ E + L KL +
Sbjct: 308 NREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEE 367
Query: 223 ----------DIQQKIATQSQITPPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEEST 272
+++Q + ++ + L + A + +K L+ +L+ +E+
Sbjct: 368 MVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAE 427
Query: 273 -ETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPN------ 325
E +++ +L K ++ ++ ++ A + K +++ L N
Sbjct: 428 LEKSSAAHTQATLLLQEKYDSMVQSLE---DVTAQFESYKALTASEIEDLKLENSSLQEK 484
Query: 326 --RTNSNLDVLKHMIHEVEHEMEEYERWT-GREVKGLQSSQGLTGFTLSLVSSLCRLVRY 382
+ N + ++H I E +EY R + K + T+S + + L
Sbjct: 485 AAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQ 544
Query: 383 LKESEIQLRKEVETRQ 398
LK+ E RK++E +
Sbjct: 545 LKQQEEDFRKQLEDEE 560
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,786,825
Number of Sequences: 37866
Number of extensions: 1546875
Number of successful extensions: 6154
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 183
Number of HSP's that attempted gapping in prelim test: 5864
Number of HSP's gapped (non-prelim): 521
length of query: 855
length of database: 18,247,518
effective HSP length: 111
effective length of query: 744
effective length of database: 14,044,392
effective search space: 10449027648
effective search space used: 10449027648
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.