Search of human proteins with 21389491

Search of human proteins with 21389491

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21389491 family with sequence similarity 82, member A1 [Homo
sapiens]
         (573 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21389491 family with sequence similarity 82, member A1 [Homo ...  1167   0.0  
gi|8922532 family with sequence similarity 82, member A2 [Homo s...   208   1e-53
gi|116875831 regulator of microtubule dynamics 1 [Homo sapiens]       122   1e-27
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    35   0.14 
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    33   0.54 
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    33   0.54 
gi|32698714 hypothetical protein LOC284058 [Homo sapiens]              32   1.6  
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    31   2.7  
gi|112821688 G protein-regulated inducer of neurite outgrowth 2 ...    31   2.7  
gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase...    31   3.5  
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            30   4.6  
gi|22538437 cathepsin B preproprotein [Homo sapiens]                   30   6.0  
gi|22538435 cathepsin B preproprotein [Homo sapiens]                   30   6.0  
gi|22538433 cathepsin B preproprotein [Homo sapiens]                   30   6.0  
gi|22538431 cathepsin B preproprotein [Homo sapiens]                   30   6.0  
gi|4503139 cathepsin B preproprotein [Homo sapiens]                    30   6.0  
gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]             30   6.0  
gi|31543297 neutral sphingomyelinase (N-SMase) activation associ...    30   7.8  
gi|221625547 neutral sphingomyelinase (N-SMase) activation assoc...    30   7.8  
gi|21735569 claspin [Homo sapiens]                                     30   7.8  
gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens]     30   7.8  
gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens]     30   7.8  
gi|153945755 zinc finger protein 608 [Homo sapiens]                    30   7.8  

>gi|21389491 family with sequence similarity 82, member A1 [Homo
           sapiens]
          Length = 573

 Score = 1167 bits (3019), Expect = 0.0
 Identities = 573/573 (100%), Positives = 573/573 (100%)

Query: 1   MGKCLSCCKEDQSFQRCSPEDQVSTDAQHRGASSISQPSISLGHKTSYSPVTHKVNAAKA 60
           MGKCLSCCKEDQSFQRCSPEDQVSTDAQHRGASSISQPSISLGHKTSYSPVTHKVNAAKA
Sbjct: 1   MGKCLSCCKEDQSFQRCSPEDQVSTDAQHRGASSISQPSISLGHKTSYSPVTHKVNAAKA 60

Query: 61  SRRLLSVSSPSFSERRYSLFVGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCGSF 120
           SRRLLSVSSPSFSERRYSLFVGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCGSF
Sbjct: 61  SRRLLSVSSPSFSERRYSLFVGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCGSF 120

Query: 121 ISRRRRFSSRKLSIVSYYKSAIFFDPQASGQNVFNLNEIEIFSKTSSNTDAKKHITISAP 180
           ISRRRRFSSRKLSIVSYYKSAIFFDPQASGQNVFNLNEIEIFSKTSSNTDAKKHITISAP
Sbjct: 121 ISRRRRFSSRKLSIVSYYKSAIFFDPQASGQNVFNLNEIEIFSKTSSNTDAKKHITISAP 180

Query: 181 EYNTKNFKNFETNTTSPAFGNTIDTASYQQSTSSFFSLASDISSPDQQNGIANDIQQRGQ 240
           EYNTKNFKNFETNTTSPAFGNTIDTASYQQSTSSFFSLASDISSPDQQNGIANDIQQRGQ
Sbjct: 181 EYNTKNFKNFETNTTSPAFGNTIDTASYQQSTSSFFSLASDISSPDQQNGIANDIQQRGQ 240

Query: 241 LCKDLKDFLHPRPESYSTDHSPIMIPQHPSQSGTFPFLHKAGFSSSYKNSGCFIPPQSEL 300
           LCKDLKDFLHPRPESYSTDHSPIMIPQHPSQSGTFPFLHKAGFSSSYKNSGCFIPPQSEL
Sbjct: 241 LCKDLKDFLHPRPESYSTDHSPIMIPQHPSQSGTFPFLHKAGFSSSYKNSGCFIPPQSEL 300

Query: 301 TSGLFEDEDFAVLFQDEDRSSPIEIPKIRYITANTDTEEQSFPVPKAFNTRVEELNLDVL 360
           TSGLFEDEDFAVLFQDEDRSSPIEIPKIRYITANTDTEEQSFPVPKAFNTRVEELNLDVL
Sbjct: 301 TSGLFEDEDFAVLFQDEDRSSPIEIPKIRYITANTDTEEQSFPVPKAFNTRVEELNLDVL 360

Query: 361 LQKVDHLRMSESGKSESFELLRDHKEKFRDEIEFMWRFARAYGDMYELSTNTQEKKHYAN 420
           LQKVDHLRMSESGKSESFELLRDHKEKFRDEIEFMWRFARAYGDMYELSTNTQEKKHYAN
Sbjct: 361 LQKVDHLRMSESGKSESFELLRDHKEKFRDEIEFMWRFARAYGDMYELSTNTQEKKHYAN 420

Query: 421 IGKTLSERAINRAPMNGHCHLWYAVLCGYVSEFEGLQNKINYGHLFKEHLDIAIKLLPEE 480
           IGKTLSERAINRAPMNGHCHLWYAVLCGYVSEFEGLQNKINYGHLFKEHLDIAIKLLPEE
Sbjct: 421 IGKTLSERAINRAPMNGHCHLWYAVLCGYVSEFEGLQNKINYGHLFKEHLDIAIKLLPEE 480

Query: 481 PFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPNYM 540
           PFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPNYM
Sbjct: 481 PFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPNYM 540

Query: 541 YLAKCYTDLEENQNALKFCNLALLLPTVTKEEL 573
           YLAKCYTDLEENQNALKFCNLALLLPTVTKEEL
Sbjct: 541 YLAKCYTDLEENQNALKFCNLALLLPTVTKEEL 573


>gi|8922532 family with sequence similarity 82, member A2 [Homo
           sapiens]
          Length = 470

 Score =  208 bits (529), Expect = 1e-53
 Identities = 107/215 (49%), Positives = 140/215 (65%), Gaps = 1/215 (0%)

Query: 360 LLQKVDHL-RMSESGKSESFELLRDHKEKFRDEIEFMWRFARAYGDMYELSTNTQEKKHY 418
           LLQ+ D L R  E GK E F+LL ++K  +    +F+WR ARAY DM EL+    EKK Y
Sbjct: 241 LLQQADELHRGDEQGKREGFQLLLNNKLVYGSRQDFLWRLARAYSDMCELTEEVSEKKSY 300

Query: 419 ANIGKTLSERAINRAPMNGHCHLWYAVLCGYVSEFEGLQNKINYGHLFKEHLDIAIKLLP 478
           A  GK  +E A+ +   +  CHLWYAVLCG ++E E +Q +I  G  FKEH+D AI L P
Sbjct: 301 ALDGKEEAEAALEKGDESADCHLWYAVLCGQLAEHESIQRRIQSGFSFKEHVDKAIALQP 360

Query: 479 EEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPN 538
           E P  ++L GR+CY VS LSW+EKK A  L     S+TV++AL +FLKAEEL PG+S   
Sbjct: 361 ENPMAHFLLGRWCYQVSHLSWLEKKTATALLESPLSATVEDALQSFLKAEELQPGFSKAG 420

Query: 539 YMYLAKCYTDLEENQNALKFCNLALLLPTVTKEEL 573
            +Y++KCY +L +N  A  +  LAL LP VTKE+L
Sbjct: 421 RVYISKCYRELGKNSEARWWMKLALELPDVTKEDL 455


>gi|116875831 regulator of microtubule dynamics 1 [Homo sapiens]
          Length = 314

 Score =  122 bits (305), Expect = 1e-27
 Identities = 71/218 (32%), Positives = 126/218 (57%), Gaps = 6/218 (2%)

Query: 357 LDVLLQKVDHLRMSESGKSES-FELLRDHKEKFRDEIEFMWRFARAYGDMYELS-TNTQE 414
           ++ +L++ D+L   ESG++E  ++LL  +KE   ++ E +WR ARA  D+ +LS T+ +E
Sbjct: 83  VEEILEQADYLY--ESGETEKLYQLLTQYKES--EDAELLWRLARASRDVAQLSRTSEEE 138

Query: 415 KKHYANIGKTLSERAINRAPMNGHCHLWYAVLCGYVSEFEGLQNKINYGHLFKEHLDIAI 474
           KK         ++RA+ +   +   H WYA+    V ++EG++ KI   ++ KEH + AI
Sbjct: 139 KKLLVYEALEYAKRALEKNESSFASHKWYAICLSDVGDYEGIKAKIANAYIIKEHFEKAI 198

Query: 475 KLLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGY 534
           +L P++    +L G +CYT +++ W ++++A  LF   PSST ++AL  F +AE++ P +
Sbjct: 199 ELNPKDATSIHLMGIWCYTFAEMPWYQRRIAKMLFATPPSSTYEKALGYFHRAEQVDPNF 258

Query: 535 SNPNYMYLAKCYTDLEENQNALKFCNLALLLPTVTKEE 572
            + N + L K Y  L   + A  +   A   P  T+E+
Sbjct: 259 YSKNLLLLGKTYLKLHNKKLAAFWLMKAKDYPAHTEED 296


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 59/280 (21%), Positives = 100/280 (35%)

Query: 11   DQSFQRCSPEDQVSTDAQHRGASSISQPSISLGHKTSYSPVTHKVNAAKASRRLLSVSSP 70
            D S    S +   S+D+ +   SS S  S      ++ S      N++ +S    S  S 
Sbjct: 745  DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804

Query: 71   SFSERRYSLFVGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCGSFISRRRRFSSR 130
            + S+   S        + S     S  + DS   +  +D   SSD   S  S R   S+ 
Sbjct: 805  NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864

Query: 131  KLSIVSYYKSAIFFDPQASGQNVFNLNEIEIFSKTSSNTDAKKHITISAPEYNTKNFKNF 190
              S  S   S       +S  N  + +     S  SS++D+      S    ++ +  + 
Sbjct: 865  SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924

Query: 191  ETNTTSPAFGNTIDTASYQQSTSSFFSLASDISSPDQQNGIANDIQQRGQLCKDLKDFLH 250
            E++ +S    ++  + S   S SS  S +SD S+    +  ++          D  +   
Sbjct: 925  ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984

Query: 251  PRPESYSTDHSPIMIPQHPSQSGTFPFLHKAGFSSSYKNS 290
                S S+D S      + S S        +  SS   NS
Sbjct: 985  SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 33.5 bits (75), Expect = 0.54
 Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 19/139 (13%)

Query: 10  EDQSFQRCSPEDQVST------DAQHRGASSISQPSISLGHKTSYSPVTHKVNAAKASRR 63
           EDQ     S ED   T      +++   A S S  S++   ++  SP     ++++   +
Sbjct: 376 EDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDEN-SSSQEGLQ 434

Query: 64  LLSVSSPSFSERRYSLFVGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCGSFISR 123
             S S+ S SE  +S      + + S     SR    S+ED+  T+ KSSS+  G    +
Sbjct: 435 SHSSSAESQSEESHS------EEDDSDSQDSSR----SKEDSNSTESKSSSEEDGQL--K 482

Query: 124 RRRFSSRKLSIVSYYKSAI 142
                SRKL++ +Y+   I
Sbjct: 483 NIEIESRKLTVDAYHNKPI 501


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 33.5 bits (75), Expect = 0.54
 Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 19/139 (13%)

Query: 10  EDQSFQRCSPEDQVST------DAQHRGASSISQPSISLGHKTSYSPVTHKVNAAKASRR 63
           EDQ     S ED   T      +++   A S S  S++   ++  SP     ++++   +
Sbjct: 360 EDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDEN-SSSQEGLQ 418

Query: 64  LLSVSSPSFSERRYSLFVGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCGSFISR 123
             S S+ S SE  +S      + + S     SR    S+ED+  T+ KSSS+  G    +
Sbjct: 419 SHSSSAESQSEESHS------EEDDSDSQDSSR----SKEDSNSTESKSSSEEDGQL--K 466

Query: 124 RRRFSSRKLSIVSYYKSAI 142
                SRKL++ +Y+   I
Sbjct: 467 NIEIESRKLTVDAYHNKPI 485


>gi|32698714 hypothetical protein LOC284058 [Homo sapiens]
          Length = 1105

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 41/155 (26%), Positives = 59/155 (38%), Gaps = 32/155 (20%)

Query: 249 LHPRPESYSTDHSPIMIPQHPSQSGTFPFLHKAGFSSSYKNSGCFIPPQSELTSGLFEDE 308
           L+P P  +  +HS + +  H S+       H    SSS   +    PP S L   L    
Sbjct: 772 LNPPPPVHDPNHSKMRLRDHSSERSEV-LKHHTDMSSSSYLAATHHPPHSPLVRQLSTSS 830

Query: 309 DFAVLFQDEDRSSPIEIPKIRYITANTDTE-------EQSF-------PVPKAFNTRVEE 354
           D           SP        +TA+T  +       E SF       P+  A  TRVE+
Sbjct: 831 D-----------SPAPASSSSQVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEK 879

Query: 355 LNLDVLL----QKVD--HLRMSESGKSESFELLRD 383
           L    +L    ++VD   L+ S   ++E  E L D
Sbjct: 880 LQYKEILTPSWREVDLQSLKGSPDEENEEIEDLSD 914


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 15/55 (27%), Positives = 27/55 (49%)

Query: 361 LQKVDHLRMSESGKSESFELLRDHKEKFRDEIEFMWRFARAYGDMYELSTNTQEK 415
           +Q+ + +R  E    E  E +R+ KEK R++ E +W       +  E+    +EK
Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614


>gi|112821688 G protein-regulated inducer of neurite outgrowth 2
           [Homo sapiens]
          Length = 458

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 18  SPEDQVSTDAQHRGASSISQPSISLGHKTSYS 49
           +PED+ S  A   GAS +S P + LG  T++S
Sbjct: 177 APEDETSNSAWMLGASQLSVPPLDLGDTTAHS 208


>gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase 2
           [Homo sapiens]
          Length = 883

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 37/144 (25%), Positives = 57/144 (39%), Gaps = 18/144 (12%)

Query: 215 FFSLASDISSPDQQNGIAN----DIQQRGQLCKDLKDFLHPRPESYSTDHSPIMIPQHPS 270
           +F L     SP  QN   +    DI  + + C  L  FL   P+   T      +  HP+
Sbjct: 569 YFELFPQERSPLWQNPCDDKRHKDIWSKEKTCDRLPKFLIVGPQKTGTTAIHFFLSLHPA 628

Query: 271 QSGTFP----FLHKAGFSSSYKNSGC-----FIP-PQSELTSGLFEDEDFAVLFQDE--D 318
            + +FP    F     F+S   + G      F P P +  T  LFE    A  F  E   
Sbjct: 629 VTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFFPVPSNASTDFLFEKS--ATYFDSEVVP 686

Query: 319 RSSPIEIPKIRYITANTDTEEQSF 342
           R     +P+ + IT  T+  ++++
Sbjct: 687 RRGAALLPRAKIITVLTNPADRAY 710


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 42/200 (21%), Positives = 75/200 (37%), Gaps = 19/200 (9%)

Query: 32  ASSISQPSISLGHKTSYSPVTHKVNAAKASRRLLSVSSPSFSERRYSLFVGFQKRNASPY 91
           ++  S P  S    T+ +  T   N    +  + S S+PSFS    S        +++P 
Sbjct: 362 STETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFSS---STIYSTVTSHSTPR 418

Query: 92  WQQSRANFDSEE------DTGFTDIKSSSDHCGSFISRRRRFSSRKLSIVSYYKSAIFFD 145
           +  S    ++         + FT+ K++S    SF S      +   S  S+  S    +
Sbjct: 419 FTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTE 478

Query: 146 PQASGQNVFNLNEIEIFSKTSSNTDAKKHITISAPEYNTKNFKNFETNTTSPAFGNTIDT 205
             +        +    F+ + + T+   H T S     T    N  + T+  +   T +T
Sbjct: 479 TTS--------HSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTET 530

Query: 206 ASYQQSTSSFFSLASDISSP 225
            S+  ST SF S  +   +P
Sbjct: 531 TSH--STPSFSSSITTTETP 548


>gi|22538437 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)

Query: 81  VGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCG 118
           +G+   N +PYW  + +      D GF  I    DHCG
Sbjct: 283 LGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG 320


>gi|22538435 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)

Query: 81  VGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCG 118
           +G+   N +PYW  + +      D GF  I    DHCG
Sbjct: 283 LGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG 320


>gi|22538433 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)

Query: 81  VGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCG 118
           +G+   N +PYW  + +      D GF  I    DHCG
Sbjct: 283 LGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG 320


>gi|22538431 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)

Query: 81  VGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCG 118
           +G+   N +PYW  + +      D GF  I    DHCG
Sbjct: 283 LGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG 320


>gi|4503139 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)

Query: 81  VGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCG 118
           +G+   N +PYW  + +      D GF  I    DHCG
Sbjct: 283 LGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG 320


>gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]
          Length = 880

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 30/136 (22%), Positives = 52/136 (38%), Gaps = 12/136 (8%)

Query: 3   KCLSCCKEDQSFQRCSPEDQVSTDAQHRGASSISQPSISLGHKTSYSPVTHKVNAAKASR 62
           +C S   +  SF +  P   V  + + +   S +QP++++    S  P         + R
Sbjct: 273 RCTSLSHKPGSFLK-PPAPPVQHEVRVQDGPSQTQPTMTISRSQSPPPPVDWKTYTSSDR 331

Query: 63  RLL--SVSSP---------SFSERRYSLFVGFQKRNASPYWQQSRANFDSEEDTGFTDIK 111
           RL   + SSP         + + R  + F+  Q+R+  P W+Q  A          +  K
Sbjct: 332 RLRPPTPSSPRPRRERGAGTGASREMAPFLRCQERSLIPSWRQPTAGDSPPSPQSSSTQK 391

Query: 112 SSSDHCGSFISRRRRF 127
                C S   R  R+
Sbjct: 392 GRDPQCTSSGKREERY 407


>gi|31543297 neutral sphingomyelinase (N-SMase) activation
           associated factor isoform 1 [Homo sapiens]
          Length = 917

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 500 IEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPNYMYLAKCYTD 548
           ++ ++A T F K     + E LH   KAE + P  +NP ++    C TD
Sbjct: 173 LQSRLARTSFDKNRFQNISEKLHMECKAEMVTPLVTNPGHV----CITD 217


>gi|221625547 neutral sphingomyelinase (N-SMase) activation
           associated factor isoform 2 [Homo sapiens]
          Length = 948

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 500 IEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPNYMYLAKCYTD 548
           ++ ++A T F K     + E LH   KAE + P  +NP ++    C TD
Sbjct: 204 LQSRLARTSFDKNRFQNISEKLHMECKAEMVTPLVTNPGHV----CITD 248


>gi|21735569 claspin [Homo sapiens]
          Length = 1339

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 17/146 (11%)

Query: 210 QSTSSFFSLASDISSPDQQNGIANDIQQRGQLCKDLKDFLHPRPESYSTDHSPIMIPQHP 269
           Q T+ F   + +I + D++     +     ++ K +  FL   P+S S+D + ++     
Sbjct: 675 QETAEFLLSSEEIETKDEKEMDKENNDGSSEIGKAV-GFLSV-PKSLSSDSTLLLFKDSS 732

Query: 270 SQSGTFPFLHKAGFSSSYKNSGCFIPPQSELTSGLFEDEDFAVLFQDEDRSSPIE----- 324
           S+ G FP   K   S + +NSG       +  S L ED+  ++L ++   +S  E     
Sbjct: 733 SKMGYFPTEEK---SETDENSG-------KQPSKLDEDDSCSLLTKESSHNSSFELIGST 782

Query: 325 IPKIRYITANTDTEEQSFPVPKAFNT 350
           IP  +     T      FP    F +
Sbjct: 783 IPSYQPCNRQTGRGTSFFPTAGGFRS 808


>gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens]
          Length = 573

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 7/78 (8%)

Query: 245 LKDFLHPRPESYSTDHSPIMIPQHPSQSGTFPFLHKAGFSSSYK-------NSGCFIPPQ 297
           L+  + P+P+S   + + I    +  +         +G + S K       +SGC  PP+
Sbjct: 308 LEQAISPKPQSQKKNEADISSSANTQKPALLSSTLSSGKARSKKCKHESGDSSGCIKPPK 367

Query: 298 SELTSGLFEDEDFAVLFQ 315
           S L+  L + ED  ++ Q
Sbjct: 368 SPLSPELIQVEDLTLVSQ 385


>gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens]
          Length = 1017

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 7/78 (8%)

Query: 245 LKDFLHPRPESYSTDHSPIMIPQHPSQSGTFPFLHKAGFSSSYK-------NSGCFIPPQ 297
           L+  + P+P+S   + + I    +  +         +G + S K       +SGC  PP+
Sbjct: 308 LEQAISPKPQSQKKNEADISSSANTQKPALLSSTLSSGKARSKKCKHESGDSSGCIKPPK 367

Query: 298 SELTSGLFEDEDFAVLFQ 315
           S L+  L + ED  ++ Q
Sbjct: 368 SPLSPELIQVEDLTLVSQ 385


>gi|153945755 zinc finger protein 608 [Homo sapiens]
          Length = 1512

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 38/152 (25%), Positives = 60/152 (39%), Gaps = 24/152 (15%)

Query: 194  TTSPAFGNTIDTASYQQSTSSFFSLASDISSP----DQQNGIANDIQQRGQLCKDLKDFL 249
            T+SPA+ +  D A    S S    + S  SSP      ++ +             LK+  
Sbjct: 934  TSSPAYSDISDAADDGGSDSRSEGMRSKASSPSDIISSKDSVVKGHSSTTAQSSQLKESH 993

Query: 250  HPRPESYSTDHSPIMIPQHPSQSGTFPFLHKAGFSSSYKNSGCFIPPQSELTSGLFEDED 309
             P   SY   +SP  +  HP Q G       AG S S    G  I  +SE      ED  
Sbjct: 994  SPYYHSYDPYYSPSYM--HPGQVGA----PAAGNSGS--TQGMKIKKESE------EDA- 1038

Query: 310  FAVLFQDEDRSSPIEIPKIRYITANTDTEEQS 341
                 + +D++  ++  K+ + +A+   + QS
Sbjct: 1039 -----EKKDKAEQLDSKKVDHNSASLQPQHQS 1065


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,136,165
Number of Sequences: 37866
Number of extensions: 1010339
Number of successful extensions: 2729
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2704
Number of HSP's gapped (non-prelim): 35
length of query: 573
length of database: 18,247,518
effective HSP length: 108
effective length of query: 465
effective length of database: 14,157,990
effective search space: 6583465350
effective search space used: 6583465350
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.