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Search of human proteins with 21322252
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21322252 androgen receptor isoform 1 [Homo sapiens]
(920 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 1890 0.0
gi|58535455 androgen receptor isoform 2 [Homo sapiens] 785 0.0
gi|110611914 progesterone receptor [Homo sapiens] 449 e-126
gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho... 394 e-109
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof... 391 e-108
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof... 391 e-108
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof... 391 e-108
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof... 391 e-108
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo... 391 e-108
gi|66528677 nuclear receptor subfamily 3, group C, member 1 isof... 389 e-108
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof... 354 2e-97
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 162 1e-39
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 162 1e-39
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 162 1e-39
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 162 1e-39
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens] 158 3e-38
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens] 158 3e-38
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens] 158 3e-38
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 147 4e-35
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 146 8e-35
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 146 8e-35
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 146 8e-35
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 146 8e-35
gi|238550159 estrogen-related receptor beta [Homo sapiens] 144 4e-34
gi|11415052 retinoid X receptor, beta [Homo sapiens] 117 4e-26
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 117 6e-26
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 116 8e-26
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 116 1e-25
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 114 5e-25
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 112 2e-24
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 1890 bits (4896), Expect = 0.0
Identities = 920/920 (100%), Positives = 920/920 (100%)
Query: 1 MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ 60
MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ
Sbjct: 1 MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ 60
Query: 61 QQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQ 120
QQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQ
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQ 120
Query: 121 SALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSAD 180
SALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSAD
Sbjct: 121 SALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSAD 180
Query: 181 LKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELC 240
LKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELC
Sbjct: 181 LKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELC 240
Query: 241 KAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAG 300
KAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAG
Sbjct: 241 KAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAG 300
Query: 301 KSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQ 360
KSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQ
Sbjct: 301 KSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQ 360
Query: 361 SRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAA 420
SRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAA
Sbjct: 361 SRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAA 420
Query: 421 GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAP 480
GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAP
Sbjct: 421 GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAP 480
Query: 481 YGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRL 540
YGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRL
Sbjct: 481 YGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRL 540
Query: 541 ETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRN 600
ETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRN
Sbjct: 541 ETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRN 600
Query: 601 DCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKL 660
DCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKL
Sbjct: 601 DCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKL 660
Query: 661 TVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA 720
TVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA
Sbjct: 661 TVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA 720
Query: 721 KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSR 780
KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSR
Sbjct: 721 KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSR 780
Query: 781 MYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELD 840
MYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELD
Sbjct: 781 MYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELD 840
Query: 841 RIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEII 900
RIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEII
Sbjct: 841 RIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEII 900
Query: 901 SVQVPKILSGKVKPIYFHTQ 920
SVQVPKILSGKVKPIYFHTQ
Sbjct: 901 SVQVPKILSGKVKPIYFHTQ 920
>gi|58535455 androgen receptor isoform 2 [Homo sapiens]
Length = 388
Score = 785 bits (2028), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 540 LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR 599
LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR
Sbjct: 8 LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR 67
Query: 600 NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK 659
NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK
Sbjct: 68 NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK 127
Query: 660 LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW 719
LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW
Sbjct: 128 LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW 187
Query: 720 AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS 779
AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS
Sbjct: 188 AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS 247
Query: 780 RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL 839
RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL
Sbjct: 248 RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL 307
Query: 840 DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI 899
DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI
Sbjct: 308 DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI 367
Query: 900 ISVQVPKILSGKVKPIYFHTQ 920
ISVQVPKILSGKVKPIYFHTQ
Sbjct: 368 ISVQVPKILSGKVKPIYFHTQ 388
>gi|110611914 progesterone receptor [Homo sapiens]
Length = 933
Score = 449 bits (1155), Expect = e-126
Identities = 335/951 (35%), Positives = 458/951 (48%), Gaps = 146/951 (15%)
Query: 46 SAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPT 105
SA P LL + Q Q ++ Q QQ E + + + +G GS + +
Sbjct: 49 SAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDS 108
Query: 106 GYL--VLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKG--LPQQLPAPPDEDDSAAP 161
G L VLD PS P + P P A S +LP ED AAP
Sbjct: 109 GLLDSVLDTLLAPSGPGQSQ---------PSPPACEVTSSWCLFGPELP----EDPPAAP 155
Query: 162 STLSLLGPTFP------GLSSCSADLKDILSE--ASTMQLL---------------QQQQ 198
+T +L P G SS +A +L + QLL Q
Sbjct: 156 ATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQ 215
Query: 199 QEAVSEGSSSGRAREASGAPT-SSKDNYLGGTSTISDNAKELCKAVSVSMGLG------- 250
AV G E S P K LGG + A A + + L
Sbjct: 216 AAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRF 275
Query: 251 -------VEALEHLSPGEQLRG----DCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSA 299
VE ++PG D ++ P+L + A+ L E + D A
Sbjct: 276 SAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDES--YDGGA 333
Query: 300 GKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLE------LPSTLSLYKSGAL 353
G ++ S T G+ C+ A P L + +
Sbjct: 334 GAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEG 393
Query: 354 DEAAAYQSRDYY----------NFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAA 403
EA+A R Y +FPL GPPPP PP A
Sbjct: 394 AEASARSPRSYLVAGANPAAFPDFPL---GPPPPLPP---------------------RA 429
Query: 404 AQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHT---LFTAE-----EGQLYGP-CGGGG 454
R G+ A A P S S S+A+SS L+ AE +G P C G
Sbjct: 430 TPSRPGEAAV-----TAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPG 484
Query: 455 GGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSR-VP 513
G G AGA AP Y P GL G P + Y ++ +P
Sbjct: 485 ASGCLLPRDGLPSTSASAAAAGA-APALY--PALGLNG------LPQLGYQAAVLKEGLP 535
Query: 514 YPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYG 573
P P+++ +R ++ + PQK CLICGDEASGCHYG
Sbjct: 536 QVYP--------PYLNY-------LRPDSEASQSPQYSFESLPQKICLICGDEASGCHYG 580
Query: 574 ALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLK 633
LTCGSCKVFFKRA EG+ YLCA RNDC +DK RRKNCP+CRLRKC +AGM LG RK K
Sbjct: 581 VLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFK 640
Query: 634 KLGNLKLQEEGEASSTTSP------TEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVC 687
K +++ +A + P ++ +Q+ T S + + P +N+L +IEP V+
Sbjct: 641 KFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIY 700
Query: 688 AGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMV 747
AGHDN +PD+ ++LL+SLN+LGERQL+ VVKW+K+LPGFRNLH+DDQ+ +IQYSWM LMV
Sbjct: 701 AGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMV 760
Query: 748 FAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLC 807
F +GWRS+ +V+ +MLYFAPDL+ NE RM +S YS C+ M + QEF LQ++ +EFLC
Sbjct: 761 FGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLC 820
Query: 808 MKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSV 867
MK LLL + IP++GL++Q F+E+R +YI+EL + I ++K S S+RFYQLTKLLD++
Sbjct: 821 MKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNL 880
Query: 868 QPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFH 918
+ ++LH + + I+S +SV+FPEMM+E+I+ Q+PKIL+G VKP+ FH
Sbjct: 881 HDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFH 931
>gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo
sapiens]
Length = 984
Score = 394 bits (1011), Expect = e-109
Identities = 203/388 (52%), Positives = 256/388 (65%), Gaps = 29/388 (7%)
Query: 556 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 615
P K CL+CGDEASGCHYG +TCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+C
Sbjct: 599 PSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 658
Query: 616 RLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTT---------SPTEETT--------- 657
RL+KC +AGM LGARK KKLG LK E + SP E TT
Sbjct: 659 RLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPS 718
Query: 658 -------QKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGE 710
Q T+S P + VLE IEP +V AG+D+++PD+ LLS+LN L
Sbjct: 719 VNTALVPQLSTISRA----LTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAG 774
Query: 711 RQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLV 770
+Q++ VVKWAK LPGF+NL ++DQ+ +IQYSWM L FA+ WRS+ + NS+ LYFAPDLV
Sbjct: 775 KQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLV 834
Query: 771 FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDE 830
FNE +MH+S MY C M +S +F LQ+T +E+ MK LLL S IP DGLK+Q F+E
Sbjct: 835 FNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEE 894
Query: 831 LRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSV 890
+R NYIKEL +++ N +RFYQLTKLLDS+ + +L +F F +SH + V
Sbjct: 895 MRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKV 954
Query: 891 DFPEMMAEIISVQVPKILSGKVKPIYFH 918
+FP M+ EIIS Q+PK+ SG KP+YFH
Sbjct: 955 EFPAMLVEIISDQLPKVESGNAKPLYFH 982
>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-108
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 555 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 614
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 615 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 671
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 672 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 731
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 732 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 791
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 792 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 851
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 852 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 911
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 912 VKPIYFH 918
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-108
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 555 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 614
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 615 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 671
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 672 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 731
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 732 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 791
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 792 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 851
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 852 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 911
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 912 VKPIYFH 918
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-108
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 555 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 614
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 615 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 671
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 672 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 731
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 732 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 791
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 792 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 851
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 852 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 911
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 912 VKPIYFH 918
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-108
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 555 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 614
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 615 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 671
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 672 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 731
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 732 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 791
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 792 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 851
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 852 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 911
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 912 VKPIYFH 918
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-108
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 555 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 614
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 615 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 671
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 672 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 731
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 732 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 791
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 792 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 851
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 852 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 911
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 912 VKPIYFH 918
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|66528677 nuclear receptor subfamily 3, group C, member 1 isoform
gamma [Homo sapiens]
Length = 778
Score = 389 bits (999), Expect = e-108
Identities = 193/368 (52%), Positives = 255/368 (69%), Gaps = 11/368 (2%)
Query: 555 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQ-KYLCASRNDCTIDKFRRKNCP 613
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+Q YLCA RNDC IDK RRKNCP
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRNDCIIDKIRRKNCP 475
Query: 614 SCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYEC 670
+CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 ACRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQL 529
Query: 671 QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLH 730
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH
Sbjct: 530 TPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLH 589
Query: 731 VDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRH 790
+DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M +
Sbjct: 590 LDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLY 649
Query: 791 LSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNP 850
+S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N
Sbjct: 650 VSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNS 709
Query: 851 TSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSG 910
+ +RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 SQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNG 768
Query: 911 KVKPIYFH 918
+K + FH
Sbjct: 769 NIKKLLFH 776
>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
beta [Homo sapiens]
Length = 742
Score = 354 bits (908), Expect = 2e-97
Identities = 173/316 (54%), Positives = 224/316 (70%), Gaps = 9/316 (2%)
Query: 555 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 614
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 615 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 671
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 672 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 731
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 732 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 791
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 792 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 851
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 852 SCSRRFYQLTKLLDSV 867
+RFYQLTKLLDS+
Sbjct: 710 QNWQRFYQLTKLLDSM 725
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 162 bits (411), Expect = 1e-39
Identities = 128/465 (27%), Positives = 209/465 (44%), Gaps = 64/465 (13%)
Query: 441 AEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGG-EAGAVAPYGYTRPPQGLAGQESDFTA 499
A Q+YG G G G G G GG + + +P PP L S F
Sbjct: 67 AANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQL----SPFLQ 122
Query: 500 PDVWYPGGMVSRVPY-----PSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPID--- 551
P +VPY PS V+ E GP ++ P D R + R+ + +
Sbjct: 123 PHG-------QQVPYYLENEPSGYTVR-EAGP--PAFYRPNSDNRRQGGRERLASTNDKG 172
Query: 552 ----YYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKF 607
+ C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK
Sbjct: 173 SMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKN 232
Query: 608 RRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS------- 651
RRK+C +CRLRKCYE GM G + + G L+ + GE S
Sbjct: 233 RRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLW 292
Query: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
P+ ++ + + ++ L EP ++ + +D +P S A+++ L L +R
Sbjct: 293 PSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR 352
Query: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
+LVH++ WAK +PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+
Sbjct: 353 ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLL 410
Query: 772 NEYRMHKSRMYSQCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPV 819
+ R +CV + S F + + +EF+C+K+++L +
Sbjct: 411 D-------RNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLS 463
Query: 820 DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 864
LK+ + D + K D +I K + ++ +L +LL
Sbjct: 464 STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 162 bits (411), Expect = 1e-39
Identities = 128/465 (27%), Positives = 209/465 (44%), Gaps = 64/465 (13%)
Query: 441 AEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGG-EAGAVAPYGYTRPPQGLAGQESDFTA 499
A Q+YG G G G G G GG + + +P PP L S F
Sbjct: 67 AANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQL----SPFLQ 122
Query: 500 PDVWYPGGMVSRVPY-----PSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPID--- 551
P +VPY PS V+ E GP ++ P D R + R+ + +
Sbjct: 123 PHG-------QQVPYYLENEPSGYTVR-EAGP--PAFYRPNSDNRRQGGRERLASTNDKG 172
Query: 552 ----YYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKF 607
+ C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK
Sbjct: 173 SMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKN 232
Query: 608 RRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS------- 651
RRK+C +CRLRKCYE GM G + + G L+ + GE S
Sbjct: 233 RRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLW 292
Query: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
P+ ++ + + ++ L EP ++ + +D +P S A+++ L L +R
Sbjct: 293 PSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR 352
Query: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
+LVH++ WAK +PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+
Sbjct: 353 ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLL 410
Query: 772 NEYRMHKSRMYSQCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPV 819
+ R +CV + S F + + +EF+C+K+++L +
Sbjct: 411 D-------RNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLS 463
Query: 820 DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 864
LK+ + D + K D +I K + ++ +L +LL
Sbjct: 464 STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 162 bits (411), Expect = 1e-39
Identities = 128/465 (27%), Positives = 209/465 (44%), Gaps = 64/465 (13%)
Query: 441 AEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGG-EAGAVAPYGYTRPPQGLAGQESDFTA 499
A Q+YG G G G G G GG + + +P PP L S F
Sbjct: 67 AANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQL----SPFLQ 122
Query: 500 PDVWYPGGMVSRVPY-----PSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPID--- 551
P +VPY PS V+ E GP ++ P D R + R+ + +
Sbjct: 123 PHG-------QQVPYYLENEPSGYTVR-EAGP--PAFYRPNSDNRRQGGRERLASTNDKG 172
Query: 552 ----YYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKF 607
+ C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK
Sbjct: 173 SMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKN 232
Query: 608 RRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS------- 651
RRK+C +CRLRKCYE GM G + + G L+ + GE S
Sbjct: 233 RRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLW 292
Query: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
P+ ++ + + ++ L EP ++ + +D +P S A+++ L L +R
Sbjct: 293 PSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR 352
Query: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
+LVH++ WAK +PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+
Sbjct: 353 ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLL 410
Query: 772 NEYRMHKSRMYSQCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPV 819
+ R +CV + S F + + +EF+C+K+++L +
Sbjct: 411 D-------RNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLS 463
Query: 820 DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 864
LK+ + D + K D +I K + ++ +L +LL
Sbjct: 464 STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 162 bits (411), Expect = 1e-39
Identities = 128/465 (27%), Positives = 209/465 (44%), Gaps = 64/465 (13%)
Query: 441 AEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGG-EAGAVAPYGYTRPPQGLAGQESDFTA 499
A Q+YG G G G G G GG + + +P PP L S F
Sbjct: 67 AANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQL----SPFLQ 122
Query: 500 PDVWYPGGMVSRVPY-----PSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPID--- 551
P +VPY PS V+ E GP ++ P D R + R+ + +
Sbjct: 123 PHG-------QQVPYYLENEPSGYTVR-EAGP--PAFYRPNSDNRRQGGRERLASTNDKG 172
Query: 552 ----YYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKF 607
+ C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK
Sbjct: 173 SMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKN 232
Query: 608 RRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS------- 651
RRK+C +CRLRKCYE GM G + + G L+ + GE S
Sbjct: 233 RRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLW 292
Query: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
P+ ++ + + ++ L EP ++ + +D +P S A+++ L L +R
Sbjct: 293 PSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR 352
Query: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
+LVH++ WAK +PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+
Sbjct: 353 ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLL 410
Query: 772 NEYRMHKSRMYSQCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPV 819
+ R +CV + S F + + +EF+C+K+++L +
Sbjct: 411 D-------RNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLS 463
Query: 820 DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 864
LK+ + D + K D +I K + ++ +L +LL
Sbjct: 464 STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 158 bits (399), Expect = 3e-38
Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 560 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 619
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 620 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 673
CYE GM + ++ G ++ + A + + ++ ++ + +
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
Query: 674 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 733
L +LEA P V+ + + P + A+++ SL +L +++LVH++ WAK +PGF L + D
Sbjct: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
Query: 734 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 787
Q+ +++ WM +++ + WRS + L FAPDLV + R +CV
Sbjct: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
Query: 788 --MRHLSQEFGWLQITPQEFLCMKALLLFS 815
+ + F L++ +E+LC+KA++L +
Sbjct: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 158 bits (399), Expect = 3e-38
Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 560 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 619
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 620 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 673
CYE GM + ++ G ++ + A + + ++ ++ + +
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
Query: 674 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 733
L +LEA P V+ + + P + A+++ SL +L +++LVH++ WAK +PGF L + D
Sbjct: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
Query: 734 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 787
Q+ +++ WM +++ + WRS + L FAPDLV + R +CV
Sbjct: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
Query: 788 --MRHLSQEFGWLQITPQEFLCMKALLLFS 815
+ + F L++ +E+LC+KA++L +
Sbjct: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
Length = 530
Score = 158 bits (399), Expect = 3e-38
Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 560 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 619
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 620 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 673
CYE GM + ++ G ++ + A + + ++ ++ + +
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
Query: 674 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 733
L +LEA P V+ + + P + A+++ SL +L +++LVH++ WAK +PGF L + D
Sbjct: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
Query: 734 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 787
Q+ +++ WM +++ + WRS + L FAPDLV + R +CV
Sbjct: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
Query: 788 --MRHLSQEFGWLQITPQEFLCMKALLLFS 815
+ + F L++ +E+LC+KA++L +
Sbjct: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 147 bits (371), Expect = 4e-35
Identities = 86/262 (32%), Positives = 135/262 (51%), Gaps = 6/262 (2%)
Query: 556 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 615
P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N+C I K RRK C +C
Sbjct: 75 PKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQAC 134
Query: 616 RLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPI 673
R KC GM +L ++ G K + E P L V+ P+
Sbjct: 135 RFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPV 194
Query: 674 --FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 731
++ L +EP + A D PD +++L +L +R++V + WAK++PGF +L +
Sbjct: 195 NALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSL 254
Query: 732 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 791
DQM+V+Q WM ++V + RS + L FA DLV +E + + + L
Sbjct: 255 SDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQL 312
Query: 792 SQEFGWLQITPQEFLCMKALLL 813
+ L++ +E++ +KAL L
Sbjct: 313 VRRLQALRLEREEYVLLKALAL 334
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 146 bits (369), Expect = 8e-35
Identities = 98/342 (28%), Positives = 166/342 (48%), Gaps = 40/342 (11%)
Query: 487 PQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGP----YGDMRLET 542
P G + +++ + G+ S YPS + SGP Y D
Sbjct: 35 PGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGG---------SGPVRKLYDDCSSTI 85
Query: 543 ARDHVLPIDYYFP--PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRN 600
D +Y P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N
Sbjct: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
Query: 601 DCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASST-------TS 651
+C I K RRK+C +CR KC + GM +L ++ G K + +A ++
Sbjct: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
Query: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
P ++ K+ VSH L EP + A D PDS L++L +L +R
Sbjct: 206 PAKKPYNKI-VSH-------------LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADR 251
Query: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
+LV ++ WAK +PGF L + DQM+++Q +WM +++ + +RS + + L +A D +
Sbjct: 252 ELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIM 309
Query: 772 NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLL 813
+E + + + + L +++ +++ +EF+ +KA+ L
Sbjct: 310 DEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIAL 351
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 146 bits (369), Expect = 8e-35
Identities = 98/342 (28%), Positives = 166/342 (48%), Gaps = 40/342 (11%)
Query: 487 PQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGP----YGDMRLET 542
P G + +++ + G+ S YPS + SGP Y D
Sbjct: 35 PGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGG---------SGPVRKLYDDCSSTI 85
Query: 543 ARDHVLPIDYYFP--PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRN 600
D +Y P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N
Sbjct: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
Query: 601 DCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASST-------TS 651
+C I K RRK+C +CR KC + GM +L ++ G K + +A ++
Sbjct: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
Query: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
P ++ K+ VSH L EP + A D PDS L++L +L +R
Sbjct: 206 PAKKPYNKI-VSH-------------LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADR 251
Query: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
+LV ++ WAK +PGF L + DQM+++Q +WM +++ + +RS + + L +A D +
Sbjct: 252 ELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIM 309
Query: 772 NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLL 813
+E + + + + L +++ +++ +EF+ +KA+ L
Sbjct: 310 DEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIAL 351
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 146 bits (369), Expect = 8e-35
Identities = 98/342 (28%), Positives = 166/342 (48%), Gaps = 40/342 (11%)
Query: 487 PQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGP----YGDMRLET 542
P G + +++ + G+ S YPS + SGP Y D
Sbjct: 58 PGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGG---------SGPVRKLYDDCSSTI 108
Query: 543 ARDHVLPIDYYFP--PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRN 600
D +Y P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N
Sbjct: 109 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 168
Query: 601 DCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASST-------TS 651
+C I K RRK+C +CR KC + GM +L ++ G K + +A ++
Sbjct: 169 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 228
Query: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
P ++ K+ VSH L EP + A D PDS L++L +L +R
Sbjct: 229 PAKKPYNKI-VSH-------------LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADR 274
Query: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
+LV ++ WAK +PGF L + DQM+++Q +WM +++ + +RS + + L +A D +
Sbjct: 275 ELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIM 332
Query: 772 NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLL 813
+E + + + + L +++ +++ +EF+ +KA+ L
Sbjct: 333 DEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIAL 374
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 146 bits (369), Expect = 8e-35
Identities = 98/342 (28%), Positives = 166/342 (48%), Gaps = 40/342 (11%)
Query: 487 PQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGP----YGDMRLET 542
P G + +++ + G+ S YPS + SGP Y D
Sbjct: 35 PGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGG---------SGPVRKLYDDCSSTI 85
Query: 543 ARDHVLPIDYYFP--PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRN 600
D +Y P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N
Sbjct: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
Query: 601 DCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASST-------TS 651
+C I K RRK+C +CR KC + GM +L ++ G K + +A ++
Sbjct: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
Query: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
P ++ K+ VSH L EP + A D PDS L++L +L +R
Sbjct: 206 PAKKPYNKI-VSH-------------LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADR 251
Query: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
+LV ++ WAK +PGF L + DQM+++Q +WM +++ + +RS + + L +A D +
Sbjct: 252 ELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIM 309
Query: 772 NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLL 813
+E + + + + L +++ +++ +EF+ +KA+ L
Sbjct: 310 DEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIAL 351
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 144 bits (363), Expect = 4e-34
Identities = 86/285 (30%), Positives = 143/285 (50%), Gaps = 17/285 (5%)
Query: 535 YGDMRLETARDHVLPIDYYFP--PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQ 592
Y D D + +Y P++ CL+CGD ASG HYG +C +CK FFKR +G
Sbjct: 76 YEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNI 135
Query: 593 KYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKL----GNLKLQEEGEASS 648
+Y C + N+C I K RRK+C +CR KC + GM +L ++ K + + E+S
Sbjct: 136 EYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSP 195
Query: 649 TTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNEL 708
S K ++ I Y L EP + A P+ L++L +L
Sbjct: 196 YLSLQISPPAKKPLTKIVSY---------LLVAEPDKLYAMPPPGMPEGDIKALTTLCDL 246
Query: 709 GERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPD 768
+R+LV ++ WAK +PGF +L + DQM+++Q +WM +++ + +RS + L +A D
Sbjct: 247 ADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK--LVYAED 304
Query: 769 LVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLL 813
+ +E + + + L + + L++ +EF+ +KAL L
Sbjct: 305 YIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALAL 349
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 117 bits (294), Expect = 4e-26
Identities = 119/468 (25%), Positives = 193/468 (41%), Gaps = 61/468 (13%)
Query: 456 GGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQE-SDFTAPDVWYPGGMVSRVPY 514
G G G G G ++ + P PP G TAP + GG + P
Sbjct: 66 GEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSL---GGSGAPPPP 122
Query: 515 PSPT--------CVKSEMG------PWMDSYSGPYGDMRL--------------ETARDH 546
P P + S MG P +SGP ++ E +
Sbjct: 123 PMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPP 182
Query: 547 VLPI-DYYFPP--------QKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCA 597
VL + + PP ++ C ICGD +SG HYG +C CK FFKR Y C
Sbjct: 183 VLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCR 242
Query: 598 SRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETT 657
DCT+DK +R C CR +KC GM A + ++ +GE + +P E
Sbjct: 243 DNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAG-GAPEEMPV 301
Query: 658 QKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVV 717
++ + L V + + GV G S ++++ + ++QL +V
Sbjct: 302 DRILEAE----------LAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLV 351
Query: 718 KWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMH 777
+WAK +P F +L +DDQ+ +++ W L++ + RS +V +L A L + H
Sbjct: 352 EWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSI-DVRDGIL-LATGLHVHRNSAH 409
Query: 778 KSRMYSQCVR-MRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYI 836
+ + + R + L + +++ E C++A++LF+ GL N + LR
Sbjct: 410 SAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFN-PDAKGLSNPSEVEVLREKVY 468
Query: 837 KELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAREL--HQFTFDLL 882
L+ CK+K P RF +L L +++ I + H F F L+
Sbjct: 469 ASLETY--CKQKYPEQ-QGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 513
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 117 bits (292), Expect = 6e-26
Identities = 79/264 (29%), Positives = 123/264 (46%), Gaps = 9/264 (3%)
Query: 557 QKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCR 616
Q C++CGD++SG HYG TC CK FFKR+ Y C S DC ID+ R C CR
Sbjct: 53 QVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCR 112
Query: 617 LRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPI--F 674
L+KC+ GM ++ + G + G ++++ + S + + QP+
Sbjct: 113 LKKCFRVGM---RKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSEL 169
Query: 675 LNVLEAIEPGVVCAGHDNNQPDSFAALLSSLN--ELGERQLVHVVKWAKALPGFRNLHVD 732
+ L EP AG + A+L N EL R L V+WA+ P F L V
Sbjct: 170 IAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVA 229
Query: 733 DQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR-MRHL 791
DQ+A+++ SW L V ++ +++ L A L ++ + VR +
Sbjct: 230 DQVALLRLSWSELFVLNAA-QAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQ 288
Query: 792 SQEFGWLQITPQEFLCMKALLLFS 815
+ G LQ+ E+ C+KA+ LF+
Sbjct: 289 VDKLGRLQVDSAEYGCLKAIALFT 312
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 116 bits (291), Expect = 8e-26
Identities = 96/328 (29%), Positives = 149/328 (45%), Gaps = 25/328 (7%)
Query: 560 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 619
C ICGD +SG HYG +C CK FFKR Y C DC IDK +R C CR +K
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 620 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLE 679
C GM A + ++ K + E E ST+S E+ + V I L
Sbjct: 195 CLAMGMKREAVQEERQRG-KDRNENEVESTSSANED----MPVERI---------LEAEL 240
Query: 680 AIEPGVVCAGHDNN--QPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAV 737
A+EP N P S ++++ + ++QL +V+WAK +P F L +DDQ+ +
Sbjct: 241 AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL 300
Query: 738 IQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR-MRHLSQEFG 796
++ W L++ + RS + +L A L + H + + + R + L +
Sbjct: 301 LRAGWNELLIASFSHRSIAVKDGILL--ATGLHVHRNSAHSAGVGAIFDRVLTELVSKMR 358
Query: 797 WLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRR 856
+Q+ E C++A++LF+ GL N + LR L+ CK K P R
Sbjct: 359 DMQMDKTELGCLRAIVLFN-PDSKGLSNPAEVEALREKVYASLEAY--CKHKYPEQ-PGR 414
Query: 857 FYQLTKLLDSVQPIAREL--HQFTFDLL 882
F +L L +++ I + H F F L+
Sbjct: 415 FAKLLLRLPALRSIGLKCLEHLFFFKLI 442
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 116 bits (290), Expect = 1e-25
Identities = 95/328 (28%), Positives = 150/328 (45%), Gaps = 28/328 (8%)
Query: 560 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 619
C ICGD +SG HYG +C CK FFKR Y C DC IDK +R C CR +K
Sbjct: 139 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQK 198
Query: 620 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPI--FLNV 677
C GM A +QEE + S + +E G+E P+ L
Sbjct: 199 CLVMGMKREA----------VQEERQRSRERAESEAECA------TSGHEDMPVERILEA 242
Query: 678 LEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAV 737
A+EP G D N +S ++++ ++QL +V+WAK +P F +L ++DQ+ +
Sbjct: 243 ELAVEPKTESYG-DMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVIL 301
Query: 738 IQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR-MRHLSQEFG 796
++ W L++ + RS + + +L A L + H + + S R + L +
Sbjct: 302 LRAGWNELLIASFSHRSVSVQDGILL--ATGLHVHRSSAHSAGVGSIFDRVLTELVSKMK 359
Query: 797 WLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRR 856
+Q+ E C++A++LF+ GL N + LR L+ K+K P R
Sbjct: 360 DMQMDKSELGCLRAIVLFN-PDAKGLSNPSEVETLREKVYATLEAY--TKQKYPEQ-PGR 415
Query: 857 FYQLTKLLDSVQPIAREL--HQFTFDLL 882
F +L L +++ I + H F F L+
Sbjct: 416 FAKLLLRLPALRSIGLKCLEHLFFFKLI 443
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 114 bits (284), Expect = 5e-25
Identities = 110/440 (25%), Positives = 177/440 (40%), Gaps = 79/440 (17%)
Query: 452 GGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSR 511
GG GG GGGGG GE A G PQ GQ P
Sbjct: 17 GGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQ-TPGQPGAPATP----------- 64
Query: 512 VPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCH 571
G D GP G + ++ H+ C++CGD++SG H
Sbjct: 65 -------------GTAGDKGQGPPGSGQ---SQQHI-----------ECVVCGDKSSGKH 97
Query: 572 YGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARK 631
YG TC CK FFKR+ Y C + +C ID+ R C CRL+KC + GM
Sbjct: 98 YGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGM------ 151
Query: 632 LKKLGNLKLQEEGEASSTTSPTEETTQKLTVSH---IEGYECQPIFLNVLEAIEPGVVCA 688
+ E PT+ + +++ + G+ ++++L EP
Sbjct: 152 ---------RREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSR 202
Query: 689 -GHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMV 747
G QP++ + ++ EL R L V+WA+ +P F +L + DQ+++++ +W L V
Sbjct: 203 YGSQCMQPNNIMG-IENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFV 261
Query: 748 FAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCV--RMRHLS------QEFGWLQ 799
S L+ AP L +H S M + V M H+ ++ L
Sbjct: 262 LNAAQCSMP------LHVAPLLA--AAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALH 313
Query: 800 ITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQ 859
+ E+ C+KA++LF+ GL + + L+ L+ + + N S RF +
Sbjct: 314 VDSAEYSCLKAIVLFT-SDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPS---RFGK 369
Query: 860 LTKLLDSVQPIARELHQFTF 879
L L S++ ++ + + F
Sbjct: 370 LLLRLPSLRTVSSSVIEQLF 389
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 112 bits (279), Expect = 2e-24
Identities = 94/359 (26%), Positives = 149/359 (41%), Gaps = 65/359 (18%)
Query: 469 GGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWM 528
G G +A P PP G AP G P+ T + GP
Sbjct: 17 GSQGSQASQAPPV--PGPPPG---------APHTPQTPGQGGPASTPAQTAAGGQGGP-- 63
Query: 529 DSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAA 588
GP D + + + H+ C++CGD++SG HYG TC CK FFKR+
Sbjct: 64 ---GGPGSDKQQQ--QQHI-----------ECVVCGDKSSGKHYGQFTCEGCKSFFKRSV 107
Query: 589 EGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASS 648
Y C + +C ID+ R C CRL+KC + GM + E
Sbjct: 108 RRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGM---------------RREAVQRG 152
Query: 649 TTSPTEETTQKLTVSHIEGYECQPI---FLNVLEAIEPGVVCA-GHDNNQPDSFAALLSS 704
PT+ T + +++ + C ++++L EP G QP++ + +
Sbjct: 153 RMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMG-IEN 211
Query: 705 LNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLY 764
+ EL R L V+WA+ +P F +L + DQ+A+++ +W L V S L+
Sbjct: 212 ICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMP------LH 265
Query: 765 FAPDLVFNEYRMHKSRMYSQCV--RMRHLS------QEFGWLQITPQEFLCMKALLLFS 815
AP L +H S M + V M H+ ++ L + E+ C+KA++LF+
Sbjct: 266 VAPLLA--AAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFT 322
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,060,545
Number of Sequences: 37866
Number of extensions: 2608575
Number of successful extensions: 77367
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 963
Number of HSP's successfully gapped in prelim test: 624
Number of HSP's that attempted gapping in prelim test: 31582
Number of HSP's gapped (non-prelim): 19081
length of query: 920
length of database: 18,247,518
effective HSP length: 112
effective length of query: 808
effective length of database: 14,006,526
effective search space: 11317273008
effective search space used: 11317273008
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.