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Search of human proteins with 212549738
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|212549738 anaphase-promoting complex subunit 7 isoform b
[Homo sapiens]
(537 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|212549738 anaphase-promoting complex subunit 7 isoform b [Hom... 1051 0.0
gi|212549736 anaphase-promoting complex subunit 7 isoform a [Hom... 1049 0.0
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 55 2e-07
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 55 2e-07
gi|83415184 transmembrane and tetratricopeptide repeat containin... 53 6e-07
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 52 2e-06
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 52 2e-06
gi|118402596 cell division cycle protein 23 [Homo sapiens] 46 1e-04
gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens] 45 2e-04
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 45 2e-04
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 43 6e-04
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 42 0.001
gi|224809432 transmembrane and tetratricopeptide repeat containi... 37 0.046
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 36 0.10
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 36 0.10
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 35 0.17
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 35 0.17
gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens] 35 0.17
gi|70980549 programmed cell death 11 [Homo sapiens] 35 0.23
gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens] 35 0.23
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens] 34 0.29
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens] 34 0.29
gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens] 34 0.29
gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens] 34 0.29
gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens] 34 0.29
gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens] 34 0.29
gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens] 34 0.29
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 34 0.29
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 34 0.29
gi|118766328 transmembrane and tetratricopeptide repeat containi... 34 0.39
>gi|212549738 anaphase-promoting complex subunit 7 isoform b [Homo
sapiens]
Length = 537
Score = 1051 bits (2718), Expect = 0.0
Identities = 537/537 (100%), Positives = 537/537 (100%)
Query: 1 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL 60
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL
Sbjct: 1 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL 60
Query: 61 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST 120
LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST
Sbjct: 61 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST 120
Query: 121 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK 180
GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK
Sbjct: 121 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK 180
Query: 181 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI 240
KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI
Sbjct: 181 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI 240
Query: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML 300
KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML
Sbjct: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML 300
Query: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY 360
DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY
Sbjct: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY 360
Query: 361 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS 420
LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS
Sbjct: 361 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS 420
Query: 421 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480
NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV
Sbjct: 421 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480
Query: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALR 537
KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALR
Sbjct: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALR 537
>gi|212549736 anaphase-promoting complex subunit 7 isoform a [Homo
sapiens]
Length = 599
Score = 1049 bits (2713), Expect = 0.0
Identities = 536/536 (100%), Positives = 536/536 (100%)
Query: 1 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL 60
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL
Sbjct: 1 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL 60
Query: 61 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST 120
LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST
Sbjct: 61 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST 120
Query: 121 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK 180
GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK
Sbjct: 121 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK 180
Query: 181 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI 240
KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI
Sbjct: 181 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI 240
Query: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML 300
KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML
Sbjct: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML 300
Query: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY 360
DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY
Sbjct: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY 360
Query: 361 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS 420
LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS
Sbjct: 361 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS 420
Query: 421 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480
NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV
Sbjct: 421 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480
Query: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIAL 536
KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIAL
Sbjct: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIAL 536
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/226 (22%), Positives = 92/226 (40%), Gaps = 5/226 (2%)
Query: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332
+L + YF + + F + + ++ Y ++GM++Y L + + L L
Sbjct: 507 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 566
Query: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392
++ E W +G + + A+ +AIQ++ N A L G + +A
Sbjct: 567 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 626
Query: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCL 452
+ FR AIR+ P + + GL Y A + + K L N Q+ LL + +
Sbjct: 627 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGV 683
Query: 453 EDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 496
+ EKA L+KA+ P +A +L +KY+ +
Sbjct: 684 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSAL 729
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/226 (22%), Positives = 92/226 (40%), Gaps = 5/226 (2%)
Query: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332
+L + YF + + F + + ++ Y ++GM++Y L + + L L
Sbjct: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560
Query: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392
++ E W +G + + A+ +AIQ++ N A L G + +A
Sbjct: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620
Query: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCL 452
+ FR AIR+ P + + GL Y A + + K L N Q+ LL + +
Sbjct: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGV 677
Query: 453 EDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 496
+ EKA L+KA+ P +A +L +KY+ +
Sbjct: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSAL 723
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 53.1 bits (126), Expect = 6e-07
Identities = 75/341 (21%), Positives = 128/341 (37%), Gaps = 49/341 (14%)
Query: 161 GIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVA 220
G+ + K++ AN K G+ + ++ Y+ L+ P A+ L +L+ AE
Sbjct: 367 GVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTAEAK 426
Query: 221 SMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSL----EKK----SLLRDNVD 272
+Q P ++RA+ + +L EKK +LL+D++
Sbjct: 427 MYYQRALQLHPQ------------------HNRALFNLGNLLKSQEKKEEAITLLKDSIK 468
Query: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGM-------DVYGYLLAREGRLEDVE 325
AD Y +F++A+ + IK + YG L G E
Sbjct: 469 YGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAV 528
Query: 326 NLGCRLFNISDQHAEPWVVSGC-------HSFYSKRYSRALYLGAKAIQLNSNSVQALLL 378
+ +S H V G +S + Y RAL + KA + L
Sbjct: 529 AHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKA--------EILSP 580
Query: 379 KGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLG 438
GA N GR +EA+ ++EA L P + + L + +EA M N++
Sbjct: 581 LGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEET 640
Query: 439 ANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAV 479
+ LL+ + + +KA +DKAL +P K +
Sbjct: 641 GCLECYRLLSAIYSKQE-NHDKALDAIDKALQLKPKDPKVI 680
Score = 36.2 bits (82), Expect = 0.078
Identities = 41/175 (23%), Positives = 66/175 (37%), Gaps = 7/175 (4%)
Query: 364 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSI 423
+A+QL+ +AL G L++ + +EAI +++I+ P D Y L
Sbjct: 431 RALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERF 490
Query: 424 REAMVMANNVYKTLGANAQTLTLLAT---VCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480
+E A +Y+T N + L V L D EKA +A+ P + A+V
Sbjct: 491 KE----AEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMV 546
Query: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIA 535
L + + AL + LG Y+EA+ Y A
Sbjct: 547 NLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEA 601
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 51.6 bits (122), Expect = 2e-06
Identities = 75/370 (20%), Positives = 136/370 (36%), Gaps = 23/370 (6%)
Query: 175 LANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMT---MNVIQTVP 231
L N+YK+ GQ + ++ Y+ LR P +D + L + V ++ ++ +Q P
Sbjct: 85 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNP 144
Query: 232 NL----DWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDN 287
+L L +KA + + C L+ + +L ++ G+
Sbjct: 145 DLYCVRSDLGNLLKALGRLEE-------AKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 197
Query: 288 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGC 347
++ FE+A LDP + G +L + R ++S HA C
Sbjct: 198 WLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLAC 257
Query: 348 HSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRL 407
+ A+ +AI+L + A AL+ G V EA + A+RL P
Sbjct: 258 VYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 317
Query: 408 DCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDK 467
D L +I EA+ + + A + LA+V + QE A +
Sbjct: 318 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE-ALMHYKE 376
Query: 468 ALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNAL--------ANQSDCVLHRILGDFL 519
A+ P + A L Q + + A+ A+ + +H+ G+
Sbjct: 377 AIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIP 436
Query: 520 VAVNEYQEAM 529
A+ Y+ A+
Sbjct: 437 EAIASYRTAL 446
Score = 42.7 bits (99), Expect = 8e-04
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 343 VVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRL 402
++S H F +R R+ + AI+ N +A G + G++QEAI H+R A+RL
Sbjct: 50 LLSSIH-FQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRL 108
Query: 403 APCRLDCYEGLIECYLASNSIREAM 427
P +D Y L +A+ + A+
Sbjct: 109 KPDFIDGYINLAAALVAAGDMEGAV 133
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/147 (23%), Positives = 62/147 (42%)
Query: 270 NVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGC 329
+ D L +LA++ G+ + +V + +A + P +L ++G+L++
Sbjct: 316 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 375
Query: 330 RLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRV 389
IS A+ + G + AL +AIQ+N A + ++ G +
Sbjct: 376 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 435
Query: 390 QEAIIHFREAIRLAPCRLDCYEGLIEC 416
EAI +R A++L P D Y L C
Sbjct: 436 PEAIASYRTALKLKPDFPDAYCNLAHC 462
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 51.6 bits (122), Expect = 2e-06
Identities = 75/370 (20%), Positives = 136/370 (36%), Gaps = 23/370 (6%)
Query: 175 LANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMT---MNVIQTVP 231
L N+YK+ GQ + ++ Y+ LR P +D + L + V ++ ++ +Q P
Sbjct: 95 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNP 154
Query: 232 NL----DWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDN 287
+L L +KA + + C L+ + +L ++ G+
Sbjct: 155 DLYCVRSDLGNLLKALGRLEE-------AKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 207
Query: 288 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGC 347
++ FE+A LDP + G +L + R ++S HA C
Sbjct: 208 WLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLAC 267
Query: 348 HSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRL 407
+ A+ +AI+L + A AL+ G V EA + A+RL P
Sbjct: 268 VYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 327
Query: 408 DCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDK 467
D L +I EA+ + + A + LA+V + QE A +
Sbjct: 328 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE-ALMHYKE 386
Query: 468 ALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNAL--------ANQSDCVLHRILGDFL 519
A+ P + A L Q + + A+ A+ + +H+ G+
Sbjct: 387 AIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIP 446
Query: 520 VAVNEYQEAM 529
A+ Y+ A+
Sbjct: 447 EAIASYRTAL 456
Score = 42.7 bits (99), Expect = 8e-04
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 343 VVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRL 402
++S H F +R R+ + AI+ N +A G + G++QEAI H+R A+RL
Sbjct: 60 LLSSIH-FQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRL 118
Query: 403 APCRLDCYEGLIECYLASNSIREAM 427
P +D Y L +A+ + A+
Sbjct: 119 KPDFIDGYINLAAALVAAGDMEGAV 143
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/147 (23%), Positives = 62/147 (42%)
Query: 270 NVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGC 329
+ D L +LA++ G+ + +V + +A + P +L ++G+L++
Sbjct: 326 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 385
Query: 330 RLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRV 389
IS A+ + G + AL +AIQ+N A + ++ G +
Sbjct: 386 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 445
Query: 390 QEAIIHFREAIRLAPCRLDCYEGLIEC 416
EAI +R A++L P D Y L C
Sbjct: 446 PEAIASYRTALKLKPDFPDAYCNLAHC 472
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 10/201 (4%)
Query: 225 NVIQTVPNLDWLSV---WIKAYAFVHTGDNSRAISTICSLEKKSLLRD-----NVDLLGS 276
N+I L +LS+ W+K + H + I +L+K L D + ++
Sbjct: 211 NLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEE--ALQKYQNLIDVGFSKSSYIVSQ 268
Query: 277 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISD 336
+A Y D ++ F + + DPY I+ MD + LL ++ L L I
Sbjct: 269 IAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDK 328
Query: 337 QHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHF 396
E V G + ++ +A +A++LN + A L G M AI +
Sbjct: 329 YRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAY 388
Query: 397 REAIRLAPCRLDCYEGLIECY 417
R AI + + GL + Y
Sbjct: 389 RHAIEVNKRDYRAWYGLGQTY 409
>gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens]
Length = 1316
Score = 45.1 bits (105), Expect = 2e-04
Identities = 41/171 (23%), Positives = 77/171 (45%), Gaps = 16/171 (9%)
Query: 313 YLLAREGRLED----VENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAK---- 364
Y + REG +E +ENLG L + Q+A+ + +S+ R+ + K
Sbjct: 255 YYVCREGDIEKASTKLENLGNTLDAMEPQNAQ--LFYNITLAFSRTCGRSQLILQKIQTL 312
Query: 365 ---AIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASN 421
A LN + G + GRV+EA+ ++ A+ L + G I+C L
Sbjct: 313 LERAFSLNPQQSEFATELGYQMILQGRVKEALKWYKTAMTLDETSVSALVGFIQCQLIEG 372
Query: 422 SIREA---MVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKAL 469
+++A + N + +++G +A+ + L A + ++ QE+ LL+ L
Sbjct: 373 QLQDADQQLEFLNEIQQSIGKSAELIYLHAVLAMKKNKRQEEVINLLNDVL 423
Score = 32.7 bits (73), Expect = 0.86
Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 133 PSEIEVKYKMAECYTMLKQDKDA-IAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTS 191
P IE + KMA+ Y ++DK I I R P+ ++L + Y + ++ +
Sbjct: 685 PYFIEAREKMADIYLKHRKDKMLYITCFREIAERMANPRSFLLLGDAYMNILEPEEAIVA 744
Query: 192 YKEVLRQCP 200
Y++ L Q P
Sbjct: 745 YEQALNQNP 753
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 44.7 bits (104), Expect = 2e-04
Identities = 52/211 (24%), Positives = 99/211 (46%), Gaps = 21/211 (9%)
Query: 242 AYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLAD---LYFRAG--DNKNSVLK-FE 295
AY + +G AI ++L++ DL+ ++ Y + G D KN+ L FE
Sbjct: 150 AYVLIGSGLYDEAIRHF-----STMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFE 204
Query: 296 QAQM--LDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSK 353
+++ L+P + + +L+ GR+ + N + + A + G F S+
Sbjct: 205 LSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISE 263
Query: 354 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGL 413
Y+ A ++++LN N A+L KG + G ++EAI F+EA++ +D Y+ L
Sbjct: 264 DYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSL 323
Query: 414 IECY-------LASNSIREAMVMANNVYKTL 437
+ Y A+ S ++A+++ N +TL
Sbjct: 324 GQAYRELGNFEAATESFQKALLLNQNHVQTL 354
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/114 (29%), Positives = 49/114 (42%), Gaps = 27/114 (23%)
Query: 364 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSI 423
KA+ LN N VQ L L+G L + G +QEA+ +F+ ++L P C ++A
Sbjct: 342 KALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQF 401
Query: 424 REAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIK 477
E G AQT V L DP+ +KA P+Y+K
Sbjct: 402 YE------------GIKAQT-----KVMLNDPLPGQKAS----------PEYLK 428
Score = 29.3 bits (64), Expect = 9.5
Identities = 21/85 (24%), Positives = 36/85 (42%)
Query: 452 LEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVL 511
L D E A L + +T PD + ++AE+LS + + + L A+ Q L
Sbjct: 192 LHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARL 251
Query: 512 HRILGDFLVAVNEYQEAMDQYSIAL 536
+R G +Y A + + +L
Sbjct: 252 YRHRGTLYFISEDYATAHEDFQQSL 276
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 7/95 (7%)
Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDC 409
F S+ Y+ A ++++LN N A+L KG + G ++EAI F+EA++ +D
Sbjct: 207 FISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDA 266
Query: 410 YEGLIECY-------LASNSIREAMVMANNVYKTL 437
Y+ L + Y A+ S ++A+++ N +TL
Sbjct: 267 YKSLGQAYRELGNFEAATESFQKALLLNQNHVQTL 301
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/114 (29%), Positives = 49/114 (42%), Gaps = 27/114 (23%)
Query: 364 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSI 423
KA+ LN N VQ L L+G L + G +QEA+ +F+ ++L P C ++A
Sbjct: 289 KALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQF 348
Query: 424 REAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIK 477
E G AQT V L DP+ +KA P+Y+K
Sbjct: 349 YE------------GIKAQT-----KVMLNDPLPGQKAS----------PEYLK 375
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 10/160 (6%)
Query: 386 MGRVQEAIIHFREAIRLAP-----CRLDCYEGLIECYLASNS--IREAMVMANNVYKTLG 438
+ +V+EA+ F E IRL P C+ + Y +NS I+ AM V K
Sbjct: 414 LDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFP 473
Query: 439 ANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAEL-LSREQKYEDGIA 497
A+ L A L D KA + DK + PD V K L L +Q + G+
Sbjct: 474 RCAEGYALYAQ-ALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLE 532
Query: 498 LLRNALANQSDC-VLHRILGDFLVAVNEYQEAMDQYSIAL 536
L+ A+ + C + +G V ++A+D ++ A+
Sbjct: 533 LISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAI 572
>gi|224809432 transmembrane and tetratricopeptide repeat containing
3 [Homo sapiens]
Length = 914
Score = 37.0 bits (84), Expect = 0.046
Identities = 38/187 (20%), Positives = 81/187 (43%), Gaps = 15/187 (8%)
Query: 365 AIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGL----------- 413
A+++N N+ + G AL N + A+ +F +A + P + + +
Sbjct: 438 ALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAHMNVGRTYKNLNRTK 497
Query: 414 --IECYLASNSIREAMVMANNVYKTLGANAQTLTL-LATVCLEDPVTQEKAKTLLDKALT 470
E Y+ + S+ ++ + N + + LA + + E+A L +A++
Sbjct: 498 EAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANESRLEEADQLYRQAIS 557
Query: 471 QRPDYIKAVVKKAELLSREQK-YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAM 529
RPD+ +A + + ELL + K + A L+ ++++ L L + + E EA+
Sbjct: 558 MRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEAL 617
Query: 530 DQYSIAL 536
++ AL
Sbjct: 618 KNFNRAL 624
Score = 33.9 bits (76), Expect = 0.39
Identities = 40/201 (19%), Positives = 75/201 (37%), Gaps = 4/201 (1%)
Query: 294 FEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSK 353
+ QA + P + G LL + + + + + +A+ W K
Sbjct: 552 YRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELK 611
Query: 354 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQ---EAIIHFREAIRLAPCRLDCY 410
+ AL +A++LN AL ++ G V+ EA I P + Y
Sbjct: 612 EPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLDANGY 671
Query: 411 EGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALT 470
L + EA + K L A+ ++ + + KA +L++ L
Sbjct: 672 FNLGMLAMDDKKDNEAEIWMKKAIK-LQADFRSALFNLALLYSQTAKELKALPILEELLR 730
Query: 471 QRPDYIKAVVKKAELLSREQK 491
PD+IK ++ K ++L ++K
Sbjct: 731 YYPDHIKGLILKGDILMNQKK 751
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 35.8 bits (81), Expect = 0.10
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 23/162 (14%)
Query: 354 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGL 413
RY A + + ++++S + AL ++G L +++A+ F +A+R+AP D +
Sbjct: 135 RYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAP---DHEKAC 191
Query: 414 IECYLASNSIREAMVMANNVYK-------------TLGANAQTLTLLATVCLEDPVTQEK 460
I C A +++ N +K LG + + A + K
Sbjct: 192 IACRNA-KALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSK 250
Query: 461 AKTLLD------KALTQRPDYIKAVVKKAELLSREQKYEDGI 496
+ L D A+ YIKA +++A+ ++YE+ +
Sbjct: 251 LRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAV 292
Score = 29.3 bits (64), Expect = 9.5
Identities = 20/95 (21%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 346 GCHSFYSKRYSRALYLGAKAIQLNSNSVQA----LLLKGAALRNMGRVQEAIIHFREAIR 401
G +F Y A L +A+ ++ N+++ +G + ++ +AI A++
Sbjct: 207 GNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVK 266
Query: 402 LAPCRLDCYEGLIECYLASNSIREAMVMANNVYKT 436
L + Y +CY+ + EA+ VY+T
Sbjct: 267 LDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQT 301
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 35.8 bits (81), Expect = 0.10
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 23/162 (14%)
Query: 354 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGL 413
RY A + + ++++S + AL ++G L +++A+ F +A+R+AP D +
Sbjct: 191 RYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAP---DHEKAC 247
Query: 414 IECYLASNSIREAMVMANNVYK-------------TLGANAQTLTLLATVCLEDPVTQEK 460
I C A +++ N +K LG + + A + K
Sbjct: 248 IACRNA-KALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSK 306
Query: 461 AKTLLD------KALTQRPDYIKAVVKKAELLSREQKYEDGI 496
+ L D A+ YIKA +++A+ ++YE+ +
Sbjct: 307 LRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAV 348
Score = 29.3 bits (64), Expect = 9.5
Identities = 20/95 (21%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 346 GCHSFYSKRYSRALYLGAKAIQLNSNSVQA----LLLKGAALRNMGRVQEAIIHFREAIR 401
G +F Y A L +A+ ++ N+++ +G + ++ +AI A++
Sbjct: 263 GNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVK 322
Query: 402 LAPCRLDCYEGLIECYLASNSIREAMVMANNVYKT 436
L + Y +CY+ + EA+ VY+T
Sbjct: 323 LDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQT 357
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 35.0 bits (79), Expect = 0.17
Identities = 54/243 (22%), Positives = 97/243 (39%), Gaps = 26/243 (10%)
Query: 179 YKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSV 238
+KK + PS KE Q + D + L S ++ T I + + + V
Sbjct: 128 FKKVLKSNPSENEEKEAQSQL-IKSDEMQRLRSQALNAFGSGDYTA-AIAFLDKILEVCV 185
Query: 239 W------IKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVL 292
W ++A F+ G+ +AIS + + K L DN + ++ LY++ GD++ S+
Sbjct: 186 WDAELRELRAECFIKEGEPRKAISDLKAASK--LKNDNTEAFYKISTLYYQLGDHELSLS 243
Query: 293 KFEQAQMLDPYLIKGMDVYGYL------------LAREGRLEDVENLGCRLFNISDQHAE 340
+ + LD + Y + L R+GR D + + AE
Sbjct: 244 EVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAE 303
Query: 341 PWVVSG---CHSF-YSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHF 396
V S CH F ++ A+ + ++ +Q+ ++V AL + A EAI +
Sbjct: 304 YTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDY 363
Query: 397 REA 399
A
Sbjct: 364 ETA 366
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 35.0 bits (79), Expect = 0.17
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 10/121 (8%)
Query: 351 YSKR--YSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLD 408
Y+K+ Y +A G K + L + + K AAL + R +EA + E ++
Sbjct: 48 YAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQ 107
Query: 409 CYEGL--IECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLD 466
EGL +E LA M N+Y+ L ++ +T TLL+ DP +E + L +
Sbjct: 108 LKEGLQNMEARLAERKFMNPFNMP-NLYQKLESDPRTRTLLS-----DPTYRELIEQLRN 161
Query: 467 K 467
K
Sbjct: 162 K 162
>gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens]
Length = 977
Score = 35.0 bits (79), Expect = 0.17
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 9/95 (9%)
Query: 306 KGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVV--------SGCHSFYSKRYSR 357
+G D++ ++ ++ +E L + SDQ A P + + C+ F Y +
Sbjct: 42 EGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACY-FTMGLYEK 100
Query: 358 ALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392
AL KA+ L+S S++AL K AL +GR +EA
Sbjct: 101 ALEDSEKALGLDSESIRALFRKARALNELGRHKEA 135
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 34.7 bits (78), Expect = 0.23
Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
Query: 237 SVWIKAYAFVHTGDNSRAISTICSLEKKSL-LRDNVDLLGSLADLYFRAGDNKNSVLKFE 295
+VWIK AF+ + A + + L +++VD++ A L F+ GD + + FE
Sbjct: 1726 AVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFE 1785
Query: 296 QAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNIS 335
P VY + + G +DV ++ R+ ++S
Sbjct: 1786 NTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLS 1825
>gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens]
Length = 858
Score = 34.7 bits (78), Expect = 0.23
Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 459 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDC-VLHRILGD 517
E+AK L +ALT PD ++ + +LSR +LR+A+ QS C + LG+
Sbjct: 762 EEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGE 821
Query: 518 FLVAVNEYQEAMDQYSIAL 536
L A + + A+D + AL
Sbjct: 822 VLQAQGQNEAAVDCFLTAL 840
>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
Length = 1567
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 304 LIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRAL 359
L+K D++ LLA+ G+ DV R+ ++D A PW +S C +F + SR L
Sbjct: 601 LVKSRDMHWSLLAQRGQ-RDVSLSSLRMLIVADG-ANPWSISSCDAFLNVFQSRGL 654
>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
Length = 1571
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 304 LIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRAL 359
L+K D++ LLA+ G+ DV R+ ++D A PW +S C +F + SR L
Sbjct: 605 LVKSRDMHWSLLAQRGQ-RDVSLSSLRMLIVADG-ANPWSISSCDAFLNVFQSRGL 658
>gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]
Length = 798
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 304 LIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRAL 359
L+K D++ LLA+ G+ DV R+ ++D A PW +S C +F + SR L
Sbjct: 562 LVKSRDMHWSLLAQRGQ-RDVSLSSLRMLIVADG-ANPWSISSCDAFLNVFQSRGL 615
>gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]
Length = 1110
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 304 LIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRAL 359
L+K D++ LLA+ G+ DV R+ ++D A PW +S C +F + SR L
Sbjct: 541 LVKSRDMHWSLLAQRGQ-RDVSLSSLRMLIVADG-ANPWSISSCDAFLNVFQSRGL 594
>gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]
Length = 812
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 304 LIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRAL 359
L+K D++ LLA+ G+ DV R+ ++D A PW +S C +F + SR L
Sbjct: 605 LVKSRDMHWSLLAQRGQ-RDVSLSSLRMLIVADG-ANPWSISSCDAFLNVFQSRGL 658
>gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]
Length = 841
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 304 LIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRAL 359
L+K D++ LLA+ G+ DV R+ ++D A PW +S C +F + SR L
Sbjct: 605 LVKSRDMHWSLLAQRGQ-RDVSLSSLRMLIVADG-ANPWSISSCDAFLNVFQSRGL 658
>gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]
Length = 889
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 304 LIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRAL 359
L+K D++ LLA+ G+ DV R+ ++D A PW +S C +F + SR L
Sbjct: 605 LVKSRDMHWSLLAQRGQ-RDVSLSSLRMLIVADG-ANPWSISSCDAFLNVFQSRGL 658
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 34.3 bits (77), Expect = 0.29
Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 345 SGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 404
+ CH + Y +A +KAI+ + V+AL + AL +GR+ +A++ + + L P
Sbjct: 50 AACH-LKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEP 108
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 34.3 bits (77), Expect = 0.29
Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 345 SGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 404
+ CH + Y +A +KAI+ + V+AL + AL +GR+ +A++ + + L P
Sbjct: 65 AACH-LKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEP 123
>gi|118766328 transmembrane and tetratricopeptide repeat containing
4 isoform 2 [Homo sapiens]
Length = 741
Score = 33.9 bits (76), Expect = 0.39
Identities = 43/222 (19%), Positives = 86/222 (38%), Gaps = 9/222 (4%)
Query: 253 RAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYG 312
R+ ++C L K + ++ +LAD G+ ++ + +A L+P + M+ G
Sbjct: 472 RSALSVCPLNAKV----HYNIGKNLAD----KGNQTAAIRYYREAVRLNPKYVHAMNNLG 523
Query: 313 YLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNS 372
+L L++ E L I A W+ G KR+ A AI+
Sbjct: 524 NILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKY 583
Query: 373 VQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANN 432
G ++ R +A+ +R A L P + +I + ++ +A +
Sbjct: 584 PDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGRE 643
Query: 433 VYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPD 474
+ + + + LA V L ++++ L KA+ P+
Sbjct: 644 ALELIPNDHSLMFSLANV-LGKSQKYKESEALFLKAIKANPN 684
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,682,762
Number of Sequences: 37866
Number of extensions: 689412
Number of successful extensions: 2122
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 1973
Number of HSP's gapped (non-prelim): 148
length of query: 537
length of database: 18,247,518
effective HSP length: 107
effective length of query: 430
effective length of database: 14,195,856
effective search space: 6104218080
effective search space used: 6104218080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.