Guide to the Human Genome
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Search of human proteins with 21237808

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21237808 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform b [Homo sapiens]
         (1130 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21237808 SWI/SNF-related matrix-associated actin-dependent re...  2298   0.0  
gi|194363725 SWI/SNF-related matrix-associated actin-dependent r...  2285   0.0  
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...  2172   0.0  
gi|188536047 SWI/SNF-related matrix-associated actin-dependent r...  1337   0.0  
gi|33356148 formin-like 1 [Homo sapiens]                               78   5e-14
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    76   2e-13
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 76   2e-13
gi|57863314 vacuolar protein sorting 37C [Homo sapiens]                73   2e-12
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             70   9e-12
gi|160707881 formin 2 [Homo sapiens]                                   70   9e-12
gi|150170670 piccolo isoform 2 [Homo sapiens]                          70   1e-11
gi|150378539 piccolo isoform 1 [Homo sapiens]                          70   1e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    69   2e-11
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    69   2e-11
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]            69   3e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    69   3e-11
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        69   3e-11
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        69   3e-11
gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]          68   4e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    68   4e-11
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     67   1e-10
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     67   1e-10
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    67   1e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    66   2e-10
gi|146134388 YLP motif containing 1 [Homo sapiens]                     66   2e-10
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     66   2e-10
gi|4557317 annexin A11 [Homo sapiens]                                  65   4e-10
gi|22165433 annexin A11 [Homo sapiens]                                 65   4e-10
gi|22165431 annexin A11 [Homo sapiens]                                 65   4e-10
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    65   5e-10

>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform b [Homo sapiens]
          Length = 1130

 Score = 2298 bits (5954), Expect = 0.0
 Identities = 1130/1130 (100%), Positives = 1130/1130 (100%)

Query: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60
            MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
Sbjct: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60

Query: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120
            EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
Sbjct: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120

Query: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180
            VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
Sbjct: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180

Query: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240
            VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
Sbjct: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240

Query: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300
            WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
Sbjct: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300

Query: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
            RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
Sbjct: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360

Query: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
            VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
Sbjct: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420

Query: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
            THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480

Query: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
            LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
Sbjct: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540

Query: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
            LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP
Sbjct: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600

Query: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
            TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660

Query: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
            RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720

Query: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
            SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
Sbjct: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780

Query: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
            RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
Sbjct: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840

Query: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900
            SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
Sbjct: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900

Query: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
Sbjct: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020
            DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
Sbjct: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
Sbjct: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
            PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ
Sbjct: 1081 PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130


>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform c [Homo sapiens]
          Length = 1152

 Score = 2285 bits (5921), Expect = 0.0
 Identities = 1130/1152 (98%), Positives = 1130/1152 (98%), Gaps = 22/1152 (1%)

Query: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60
            MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
Sbjct: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60

Query: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120
            EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
Sbjct: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120

Query: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180
            VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
Sbjct: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180

Query: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240
            VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
Sbjct: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240

Query: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300
            WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
Sbjct: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300

Query: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
            RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
Sbjct: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360

Query: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
            VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
Sbjct: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420

Query: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
            THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480

Query: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
            LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
Sbjct: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540

Query: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
            LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP
Sbjct: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600

Query: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
            TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660

Query: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
            RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720

Query: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
            SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
Sbjct: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780

Query: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
            RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
Sbjct: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840

Query: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900
            SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
Sbjct: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900

Query: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
Sbjct: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020
            DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
Sbjct: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
Sbjct: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVA----------------------DPGTPLPPDPTAP 1118
            PFPNQQTPPSMMPGAVPGSGHPGVA                      DPGTPLPPDPTAP
Sbjct: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP 1140

Query: 1119 SPGTVTPVPPPQ 1130
            SPGTVTPVPPPQ
Sbjct: 1141 SPGTVTPVPPPQ 1152


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 2172 bits (5629), Expect = 0.0
 Identities = 1082/1126 (96%), Positives = 1082/1126 (96%), Gaps = 38/1126 (3%)

Query: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60
            MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
Sbjct: 1    MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ 60

Query: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120
            EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
Sbjct: 61   EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN 120

Query: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180
            VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
Sbjct: 121  VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP 180

Query: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240
            VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
Sbjct: 181  VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK 240

Query: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300
            WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
Sbjct: 241  WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK 300

Query: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
            RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
Sbjct: 301  RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360

Query: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
            VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
Sbjct: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420

Query: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
            THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480

Query: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
            LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
Sbjct: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540

Query: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
            LVPLQPKTPQ                               QTSASQQMLNFPDKGKEKP
Sbjct: 541  LVPLQPKTPQ-------------------------------QTSASQQMLNFPDKGKEKP 569

Query: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
            TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 570  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 629

Query: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
            RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 630  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 689

Query: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
            SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
Sbjct: 690  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 749

Query: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
            RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
Sbjct: 750  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 809

Query: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 900
            SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
Sbjct: 810  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA 869

Query: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
Sbjct: 870  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 929

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 1020
            DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
Sbjct: 930  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA 989

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
Sbjct: 990  PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1049

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVADP-------GTPLPPDPTAPS 1119
            PFPNQQTPPSMMPGAVPGSGHPGVA         G P PP P APS
Sbjct: 1050 PFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPPPPPPAPS 1095


>gi|188536047 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c1 [Homo sapiens]
          Length = 1105

 Score = 1337 bits (3459), Expect = 0.0
 Identities = 700/1137 (61%), Positives = 845/1137 (74%), Gaps = 85/1137 (7%)

Query: 4    RKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEV 63
            R+KDGGP  K++E+ +TV+Q D+VR+WLGK+YKKY+ A+ PTNK+L+ LVVQLLQFQE+ 
Sbjct: 32   RRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDA 91

Query: 64   FGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEM 123
            FGKHV+N   TKLP KCF+DFKAGG+LCHIL AAYK+K++QGWRR+D QNPSRMDRNVEM
Sbjct: 92   FGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEM 151

Query: 124  FMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYPVPG 183
            FM IEK+LVQNNCL+RPNI+L P+I+ KL  KLKDIIKRHQGT T++K+ ASH +YP   
Sbjct: 152  FMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSS 211

Query: 184  NLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWIL 243
            + ++EEW+RPVM+++KQVL+HWG+YPDSYDTW+ +++++A +ED P PEKP KVH KWIL
Sbjct: 212  SQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWIL 271

Query: 244  DTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGG-NYKKRKRS 302
            DTD FNEWMNEEDYEV++++ PVS R++IS K   + V SP+  RRD+K   N +KRK S
Sbjct: 272  DTDIFNEWMNEEDYEVDENRKPVSFRQRISTKN-EEPVRSPE--RRDRKASANARKRKHS 328

Query: 303  PSPSP-TP-EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
            PSP P TP E++KK+ KKG ++ Y K +    E+EQEDLTKDM++P+PVPN+EEV LPK 
Sbjct: 329  PSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKN 388

Query: 361  VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
            VN KKDSE+ PVKGGT+ DLDEQ++E++   GK++++ +   KG+Q+++ DL EDNVTEQ
Sbjct: 389  VNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPA---KGDQSRSVDLGEDNVTEQ 445

Query: 421  THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
            T+HIIIPSYA+WFDYN +H IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 446  TNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 505

Query: 481  LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
            LTSTACRRNL GDVCA+MRVHAFLEQWGL+NYQVD ESRP  MGPPPT HF+VLADTPSG
Sbjct: 506  LTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSG 565

Query: 541  LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
            LVPL  ++PQ                    VP            A+QQMLNFP+K KEKP
Sbjct: 566  LVPLHLRSPQ--------------------VP------------AAQQMLNFPEKNKEKP 593

Query: 601  TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
             D+QNFGLRTD+Y+KK + +KSK A SA REWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 594  VDLQNFGLRTDIYSKKTL-AKSKGA-SAGREWTEQETLLLLEALEMYKDDWNKVSEHVGS 651

Query: 661  RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
            RTQDECILHFLRLPIEDPYLE+S+ASLGPLAYQP+PFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 652  RTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVA 711

Query: 721  SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
            SAAAK+ALEEFS+++EEVP  LVEAHV+KV+EAA+ +GK DP +GLESS IAGT  DEPE
Sbjct: 712  SAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPE 771

Query: 781  RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
            ++E  G +E ++E     ++ E  E +     +E E  E          +K ++G++EK 
Sbjct: 772  KLE--GAEEEKMEADPDGQQPEKAENK-----VENETDEG---------DKAQDGENEKN 815

Query: 841  SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGER-----KTKVERDIGEGNLSTAAAA 895
            SEK   D  V  + + E KE +E   KE+ ++  ER     K KVE +I EGN++TAAAA
Sbjct: 816  SEKEQ-DSEVSEDTKSEEKETEEN--KELTDTCKERESDTGKKKVEHEISEGNVATAAAA 872

Query: 896  ALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQR 955
            ALA+AA KAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRE+EALE QR
Sbjct: 873  ALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQR 932

Query: 956  QQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVH 1015
            QQLL +RQ FHMEQLKYAE+RARQQ  QQ H Q  Q       G   + P GAAG P + 
Sbjct: 933  QQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQ-HSGGPGLAPLGAAGHPGMM 991

Query: 1016 GLAVAPASVV---------PAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGA 1066
                 P   +         P   G    PGS+ P + +             P+G+   G 
Sbjct: 992  PHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGS---GP 1048

Query: 1067 VPPGVPPP-----GPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAP 1118
             PPG+PP      GP  P   PN   PP       P     GV  P  P PP   AP
Sbjct: 1049 TPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPASAAP 1105


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 73/237 (30%), Positives = 95/237 (40%), Gaps = 45/237 (18%)

Query: 920  ALLVETQMKKLEIKLRHFEELET----IMDREREALEYQRQQLLADRQAFHMEQLKYAEM 975
            ALL +T+ K     L H EEL+     + +R R+A      ++    +     + +   +
Sbjct: 386  ALLEDTETKNAV--LEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETL 443

Query: 976  RARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAA----------------GPPAVHGLAV 1019
            R R      M   ++ P P   P + P  P+                   GP     + +
Sbjct: 444  RERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEI 503

Query: 1020 APASVVPAPAGSGAP-PGSLGPSEQIGQAGSTAGPQQQ-QPAGAPQPGAVPPGVPPPGPH 1077
             P +V   P+G  AP PG             T  P     PA  P PGA PP  PPP P 
Sbjct: 504  LPVAVA-TPSGGDAPTPGV-----------PTGSPSPDLAPAAEPAPGAAPP-PPPPLPG 550

Query: 1078 GPSPFPNQQTPPSMMPGA--VPGSGHPGVADP---GTPLPPDPTAPSPGTVTPVPPP 1129
             PSP   Q+ PPS  P A  +PGS  P  A P     P PP P  P PGT  PVPPP
Sbjct: 551  LPSP---QEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPP 604



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 35/106 (33%), Positives = 40/106 (37%), Gaps = 15/106 (14%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            P P L P ++P P      PP + GL     +   AP  +   PGS  P           
Sbjct: 526  PSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPP---------- 575

Query: 1052 GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097
             P    P   P P   PP  PPPG  GP P P    PP   PG  P
Sbjct: 576  -PAPPLPGDLPPPPPPPP--PPPGTDGPVPPPPPPPPPP--PGGPP 616



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 37/110 (33%), Positives = 46/110 (41%), Gaps = 13/110 (11%)

Query: 999  GSQPIP--PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQ 1056
            G  P P  PTG+  P       +APA+  PAP  +  PP  L       +A  +A PQ  
Sbjct: 514  GDAPTPGVPTGSPSPD------LAPAAE-PAPGAAPPPPPPLPGLPSPQEAPPSAPPQAP 566

Query: 1057 QPAGAPQPGAVPPGV----PPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102
               G+P+P   PP      PPP P  P P  +   PP   P   P  G P
Sbjct: 567  PLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPP 616



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 9/64 (14%)

Query: 991  QPPPALP-PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            +PPPA P PG  P PP     PP   G       V P P     PPG  GP + +G+  S
Sbjct: 573  EPPPAPPLPGDLPPPPPPPPPPPGTDG------PVPPPPPPPPPPPG--GPPDALGRRDS 624

Query: 1050 TAGP 1053
              GP
Sbjct: 625  ELGP 628


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
            tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 57/164 (34%), Positives = 62/164 (37%), Gaps = 31/164 (18%)

Query: 986  HQQQQQPPPALPPGSQPIP------------------PTGAAGPPAVHGLAVAPASVVPA 1027
            HQQQQQPPP  PP  QP P                  P  ++ P    G   AP      
Sbjct: 66   HQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAP 125

Query: 1028 PAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGP--HGPSPFPNQ 1085
            PA S APP +  P       GS  GP    P   P   + PPG PPP P   G    P Q
Sbjct: 126  PASSSAPPAT--PPTSGAPPGSGPGP---TPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ 180

Query: 1086 QTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPP 1129
               P   P AVPG G      PG    P P  P  G +   P P
Sbjct: 181  AGGPPPPPAAVPGPG------PGPKQGPGPGGPKGGKMPGGPKP 218



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 51/153 (33%), Positives = 59/153 (38%), Gaps = 32/153 (20%)

Query: 984  QMHQQQQQPPP---------ALPPGSQP----IPPTGAAGPPAVHGLAVAPA------SV 1024
            Q HQQQQ PPP         A  PG  P     PP  ++ PPA    + AP       + 
Sbjct: 92   QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTP 151

Query: 1025 VPAPAGSGAPPGS---LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG------ 1075
             P PA + APPG+     PS  +      AG     PA  P PG  P   P PG      
Sbjct: 152  TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGK 211

Query: 1076 -PHGPSPFPNQQTPPSMMPGAVPGSGHPGVADP 1107
             P GP P      P    PG  P   H G  +P
Sbjct: 212  MPGGPKPGGG---PGLSTPGGHPKPPHRGGGEP 241



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 44/134 (32%), Positives = 49/134 (36%), Gaps = 27/134 (20%)

Query: 1011 PPAVHGLAVAPASVVPAPAGSGA-PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP 1069
            PP   GL      + P P  SG  PP    P  Q          QQQ P   P P   PP
Sbjct: 34   PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQ---------QQQQPPPQQPPPQQPPP 84

Query: 1070 GVPPPGPHGPSPFPNQQTPP----------SMMPGAVPGSGH-PGVADPGTPLPPDPTAP 1118
              PPP P    P   QQ PP          +  PG  PG G  P  +    P  P  +  
Sbjct: 85   HQPPPHPQ---PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141

Query: 1119 SPGT---VTPVPPP 1129
             PG+    TP PPP
Sbjct: 142  PPGSGPGPTPTPPP 155



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 38/120 (31%), Positives = 44/120 (36%), Gaps = 15/120 (12%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPA-GSGAPPGSLGPS--EQIGQAG 1048
            PPP  P    P  P  A GPP        P + VP P  G    PG  GP   +  G   
Sbjct: 165  PPPTPPSSGVPTTPPQAGGPPP-------PPAAVPGPGPGPKQGPGPGGPKGGKMPGGPK 217

Query: 1049 STAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQ--QTPPSMMPGAVPGSGHPGVAD 1106
               GP    P G P+P     G P  G     P+  Q  Q PP   PG   G     ++D
Sbjct: 218  PGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPP---PGGPGGRSEEKISD 274



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 30/97 (30%), Positives = 35/97 (36%), Gaps = 12/97 (12%)

Query: 1033 APPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMM 1092
            +PP  +G ++  G  G   GP Q  P          P +PPP PH     P  Q PP   
Sbjct: 33   SPPPGMGLNQNRGPMGP--GPGQSGPK---------PPIPPPPPHQQQQQPPPQQPPPQQ 81

Query: 1093 PGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPP 1129
            P       HP       P PP P   S   V   P P
Sbjct: 82   PPPHQPPPHPQPHQQQQP-PPPPQDSSKPVVAQGPGP 117


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 82/307 (26%), Positives = 121/307 (39%), Gaps = 36/307 (11%)

Query: 828  DEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEG 887
            D++K  +   + +++KSDG+            +G E V ++     GER    E+  G  
Sbjct: 263  DQDKHDDSTDDSDTDKSDGE-----------SDGDEFVHRD----NGERDNNEEKKSG-- 305

Query: 888  NLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRE 947
             LS   A     +  K K++     +++  L A+++    +++  + R  EE     D +
Sbjct: 306  -LSVRFADMPGKSRKKKKNM-----KELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDED 359

Query: 948  -REALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPP--GSQPIP 1004
              +  E ++Q     ++  H +    A  + +         Q Q PP   PP  G  P P
Sbjct: 360  DSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAP 419

Query: 1005 PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQP 1064
            P    GPP   GL   P    P        PG  GP  ++   G   G     P G P P
Sbjct: 420  PLRPPGPPT--GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPP-P 476

Query: 1065 GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPD--PTAPSPGT 1122
            G +PPG PP GP    P P    PP + P   PG   P +  P  P PP   P AP P  
Sbjct: 477  G-LPPGPPPRGPPPRLPPP---APPGIPPPR-PGMMRPPLVPPLGPAPPGLFPPAPLPNP 531

Query: 1123 VTPVPPP 1129
                 PP
Sbjct: 532  GVLSAPP 538



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 85/313 (27%), Positives = 125/313 (39%), Gaps = 63/313 (20%)

Query: 830  EKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNL 889
            ++G + D    SE  DG P    + + +      +  K   ES+G+    V RD GE + 
Sbjct: 242  QRGHDDDVSSTSE-DDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEF--VHRDNGERDN 298

Query: 890  STAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRERE 949
            +    + L+   V+   +     +K K++  L   T ++ + +++   E    I +  RE
Sbjct: 299  NEEKKSGLS---VRFADMPGKSRKKKKNMKEL---TPLQAMMLRMAGQE----IPEEGRE 348

Query: 950  ALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQ--------QQQQPPPALPPGSQ 1001
              E+       D           AE ++++QH ++ H         QQQ PP ++PP   
Sbjct: 349  VEEFSEDDDEDDSDDSE------AEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402

Query: 1002 PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA 1061
              PP    GPP + G   AP    P P  +G PPG                     P GA
Sbjct: 403  QAPPM--PGPPPL-GPPPAPPLRPPGPP-TGLPPGP--------------------PPGA 438

Query: 1062 PQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPG 1121
            P P   PPG+P  G  GP P   +  PP   PG  PG   P    PG P  P P  P P 
Sbjct: 439  P-PFLRPPGMP--GLRGPLP---RLLPPGPPPGRPPGP--PPGPPPGLPPGPPPRGPPPR 490

Query: 1122 TVTP----VPPPQ 1130
               P    +PPP+
Sbjct: 491  LPPPAPPGIPPPR 503



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 37/162 (22%), Positives = 59/162 (36%), Gaps = 29/162 (17%)

Query: 922  LVETQMKKLEIKLRH-FEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRAR-Q 979
            L E  +K    KLR  FE +  + ++E   +  + ++L          +++Y + RA+  
Sbjct: 73   LNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKL----------EVEYEQKRAQLS 122

Query: 980  QHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG 1039
            Q+F  +   Q     ++P    P  P+                 +   P     PP  L 
Sbjct: 123  QYFDAVKNAQHVEVESIPLPDMPHAPSNIL--------------IQDIPLPGAQPPSILK 168

Query: 1040 PSEQIGQAGSTAGPQQQQPAGAPQ--PGAVPPGVPPPGPHGP 1079
             +   G              G P+  PG  PPG PPPGP  P
Sbjct: 169  KTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG-PPPGPPPP 209



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 15/85 (17%)

Query: 790 ARVEGQATDEKKEPKEP--------REGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES 841
           A + G++  +KK  KE         R  G  I EE +E    +   DE+   + ++EK+S
Sbjct: 311 ADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQS 370

Query: 842 EK-------SDGDPIVDPEKEKEPK 859
           +K       SDG      +++  P+
Sbjct: 371 QKQHKEESHSDGTSTASSQQQAPPQ 395


>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
          Length = 355

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 56/158 (35%), Positives = 68/158 (43%), Gaps = 16/158 (10%)

Query: 987  QQQQQPPPALPPGSQPIPPTGA--AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQI 1044
            ++Q QPP A+PP   P  P+ +   GP A   L  AP  VV  P+    P G   P+ Q+
Sbjct: 191  EEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQL 250

Query: 1045 G---QAGSTAGPQQQQPAGAPQP----GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097
            G    AG +  PQ+  P     P    GA  PG P  G   PSP   QQ+P     G  P
Sbjct: 251  GPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPP 310

Query: 1098 G------SGHPGVADPGTPL-PPDPTAPSPGTVTPVPP 1128
                      PG   P  PL PP P  P+P    P PP
Sbjct: 311  YPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPP 348



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 42/137 (30%), Positives = 49/137 (35%), Gaps = 31/137 (22%)

Query: 992  PPPALPPGSQP---------IPPTGAAGPPAVHGLAVAPA-SVVPAPAGSGAPPGSLGPS 1041
            PP   P  SQP           P    GP    G + +P  S+ P P   G P G+ GP 
Sbjct: 224  PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283

Query: 1042 EQI--GQAGSTAGPQQQ-------------QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ 1086
              +  G+A S   PQQ              QP     PG   P VP   P+ P P P   
Sbjct: 284  YPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYG 343

Query: 1087 TPPSMMPGAVPGSGHPG 1103
             PP       PG   PG
Sbjct: 344  FPPP------PGPAWPG 354



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 25/78 (32%), Positives = 29/78 (37%), Gaps = 9/78 (11%)

Query: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ-TPPSMMPGAVPGSGHPGVADPGTPL 1111
            P+  Q      P   PP    P P G  P   +Q  PP  MP       +P    P   L
Sbjct: 160  PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMP------PYPLPYSPSPSL 213

Query: 1112 PPDPTAPSPGTVTPVPPP 1129
            P  PTA   G + P P P
Sbjct: 214  PVGPTA--HGALPPAPFP 229



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 39/137 (28%), Positives = 48/137 (35%), Gaps = 36/137 (26%)

Query: 1029 AGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP----PGVP-PPGPHG---PS 1080
            AG   PP    P   + Q       +Q QP  A  P  +P    P +P  P  HG   P+
Sbjct: 167  AGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPA 226

Query: 1081 PFPNQQTP-----------PSMMPGAVPGSGH---------PGVADPGTPL----PPDP- 1115
            PFP    P           P+   G    +G+         P    PGTP+    P  P 
Sbjct: 227  PFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPL 286

Query: 1116 ---TAPSPGTVTPVPPP 1129
                APSPG     P P
Sbjct: 287  RGGRAPSPGYPQQSPYP 303


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 58/165 (35%), Positives = 71/165 (43%), Gaps = 25/165 (15%)

Query: 983  QQMHQQQQQPPPALP---PGSQPIPP-----TGAAGPPAVHGLAVAPASVVPAPAGSGAP 1034
            Q+M +Q+  PPP  P       P PP      G +GP     L +AP    P P G   P
Sbjct: 305  QEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP--PTPRGP-PP 361

Query: 1035 PGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGP----HGPSPFPNQQTPPS 1090
            PG  GP      A   +GP    P GA  P   PP  PPP P    +GP+P P    PP+
Sbjct: 362  PGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPP---LPPA 418

Query: 1091 MMP--GAVPGSGHPGVAD---PGTPLPPDPTAPSPGTVTPVPPPQ 1130
            ++P  G  PG G   + D    G  L   P AP    +   PPPQ
Sbjct: 419  LVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQ--PPPQ 461



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 34/90 (37%), Positives = 40/90 (44%), Gaps = 21/90 (23%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPA--PAGSGAPPGSLGP-SEQIGQAG 1048
            PPP  PP   P PP+   GP        AP  + PA  PAG  AP G  G   +QI Q  
Sbjct: 394  PPP--PPPPPP-PPSSGNGP--------APPPLPPALVPAGGLAPGGGRGALLDQIRQ-- 440

Query: 1049 STAGPQQQQPAGAPQPGAVPPGVPPPGPHG 1078
               G Q  +  GAP+  A+ P  PP    G
Sbjct: 441  ---GIQLNKTPGAPESSALQP--PPQSSEG 465


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 56/163 (34%), Positives = 65/163 (39%), Gaps = 30/163 (18%)

Query: 992  PPPALP-PGSQPIPPTGAAG---PPAVHGLAVAPASVVPAPA--------GSGAPPGSLG 1039
            PPP LP  G  P+PP   AG   PP + G A+ P   +P           G+G PP    
Sbjct: 922  PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981

Query: 1040 PSEQIGQAGSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQT 1087
            P   I       G     P   P  G  PP      G+PPP P        P P P    
Sbjct: 982  PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041

Query: 1088 PPSMMPGAVPGSGHPGVAD-PGTPLPPDPTAPSPGTVTPVPPP 1129
            PP   P  +PG+G P     PG  +PP P  P PG   P PPP
Sbjct: 1042 PP---PPPLPGAGIPPPPPLPGAGIPPPP--PLPGAGIPPPPP 1079



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 51/156 (32%), Positives = 61/156 (39%), Gaps = 23/156 (14%)

Query: 992  PPPALP----PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP    P   P+P  G   PP + G  + P   +P   G+G PP    P   I   
Sbjct: 999  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPP 1055

Query: 1048 GSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQTPPSMMPGA 1095
                G     P   P  G  PP      G+PPP P        P P P    PP   P  
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP---PPP 1112

Query: 1096 VPGSGHPGVAD-PGTPLPPDPTAPSPGTVTPVPPPQ 1130
            +PG+G P     PG  +PP P  P  G   P P P+
Sbjct: 1113 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPR 1148



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 54/155 (34%), Positives = 63/155 (40%), Gaps = 25/155 (16%)

Query: 992  PPPALPPGS-QPIPPTGAAG---PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP  +  P PP   AG   PP + G  + P   +P   G+G PP    P   I   
Sbjct: 944  PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPP 1000

Query: 1048 GSTAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQTPPSMMPGA 1095
                G     P   P  G  PP      G+PPP P        P P P    PP   P  
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPP 1057

Query: 1096 VPGSGHPGVAD-PGTPLPPDPTAPSPGTVTPVPPP 1129
            +PG+G P     PG  +PP P  P PG   P PPP
Sbjct: 1058 LPGAGIPPPPPLPGAGIPPPP--PLPGAGIPPPPP 1090



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 53/154 (34%), Positives = 61/154 (39%), Gaps = 24/154 (15%)

Query: 992  PPPALPPGSQPIPPTGAAG---PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG 1048
            PPP    G  P PP   AG   PP + G  + P   +P   G+G PP    P   I    
Sbjct: 967  PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPPP 1023

Query: 1049 STAGPQQQQPAGAPQPGAVPP------GVPPPGP------HGPSPFPNQQTPPSMMPGAV 1096
               G     P   P  G  PP      G+PPP P        P P P    PP   P  +
Sbjct: 1024 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPPL 1080

Query: 1097 PGSGHPGVAD-PGTPLPPDPTAPSPGTVTPVPPP 1129
            PG+G P     PG  +PP P  P PG   P PPP
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPP--PLPGVGIPPPPP 1112



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 58/163 (35%), Positives = 67/163 (41%), Gaps = 30/163 (18%)

Query: 992  PPPALP-PGSQPIPPTGAAG---PPAVHGLAVAP------ASVVPAP--AGSGAPPGSLG 1039
            PPP LP  G  P PP   AG   PP + G  + P      A + P P   G+G PP    
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091

Query: 1040 PSEQIGQAGSTAG-----PQQQQPAGAPQPGAVP-PGVPPPGP------HGPSPFPNQQT 1087
            P   I       G     P     AG P P  +P  G+PPP P        P P P    
Sbjct: 1092 PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGI 1151

Query: 1088 PPSMMPGAVPGSGHPGVAD-PGTPLPPDPTAPSPGTVTPVPPP 1129
            PP   P  +PG+G P     PG  +PP P  P PG   P PPP
Sbjct: 1152 PP---PPPLPGAGIPPPPPLPGAGIPPPP--PLPGVGIPPPPP 1189



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 57/165 (34%), Positives = 67/165 (40%), Gaps = 34/165 (20%)

Query: 992  PPPALP-PGSQPIPPTGAAG--------------PPAVHGLAVAPASVVPAPAGSGAPP- 1035
            PPP LP  G  P PP   AG              PP + G A+ P   +P  AG   PP 
Sbjct: 911  PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG-AGIPLPPP 969

Query: 1036 ---GSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP-PGVPPPGP------HGPSPFPNQ 1085
                 + P   +  AG    P     AG P P  +P  G+PPP P        P P P  
Sbjct: 970  LPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1028

Query: 1086 QTPPSMMPGAVPGSGHPGVAD-PGTPLPPDPTAPSPGTVTPVPPP 1129
              PP   P  +PG+G P     PG  +PP P  P PG   P PPP
Sbjct: 1029 GIPP---PPPLPGAGIPPPPPLPGAGIPPPP--PLPGAGIPPPPP 1068



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 51/150 (34%), Positives = 60/150 (40%), Gaps = 35/150 (23%)

Query: 992  PPPALP-PGSQPIPPTGAAG---PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP  G  P PP   AG   PP + G  + P   +P     G PP            
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPR---VGIPP------------ 1153

Query: 1048 GSTAGPQQQQPAGAPQPGAVP-PGVPPPGP------HGPSPFPNQQTPPSMMPGAVPGSG 1100
                 P     AG P P  +P  G+PPP P        P P P    PP   P  +PG+G
Sbjct: 1154 -----PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP---PPPLPGAG 1205

Query: 1101 HPGVAD-PGTPLPPDPTAPSPGTVTPVPPP 1129
             P     PG  +PP P  P P   T +PPP
Sbjct: 1206 IPPPPPLPGMGIPPAPAPPLPPPGTGIPPP 1235



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 43/136 (31%), Positives = 56/136 (41%), Gaps = 30/136 (22%)

Query: 992  PPPALP----PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP    P   P+P  G   PP + G  + P   +P   G+G PP            
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP---GAGIPP------------ 1175

Query: 1048 GSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQTPPSMMPG-AVPGSGHPGVA 1105
                 P      G P P  +P  G+PPP P   +  P    PP  +PG  +P +  P + 
Sbjct: 1176 -----PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIP----PPPPLPGMGIPPAPAPPLP 1226

Query: 1106 DPGTPLPPDPTAPSPG 1121
             PGT +PP P  P  G
Sbjct: 1227 PPGTGIPPPPLLPVSG 1242



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 48/142 (33%), Positives = 57/142 (40%), Gaps = 21/142 (14%)

Query: 992  PPPALPP-GSQPIPPTGAAG---PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PPP LP  G  P PP   AG   PP + G  + P   +P   G G PP    P   I   
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GVGIPPPPPLPGVGI--- 1195

Query: 1048 GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADP 1107
                 P     AG P P  +P    PP P  P P P    PP   P  +P SG P +   
Sbjct: 1196 ---PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP---PPLLPVSGPPLLPQV 1249

Query: 1108 GTPLPPDPTAPSPGTVTPVPPP 1129
            G+      T P+P     +PPP
Sbjct: 1250 GS-----STLPTPQVCGFLPPP 1266



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 86/361 (23%), Positives = 128/361 (35%), Gaps = 101/361 (27%)

Query: 844  SDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVK 903
            S G P   P++E   ++ + E    V E+  +R   V++++ +               +K
Sbjct: 624  SMGPPSKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVD---------------MK 668

Query: 904  AKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQ 963
            ++  A V ++  +++  L   T++ +LE   R +  L+T +    + LE     + A   
Sbjct: 669  SEGQATVIQQLEQTIEDL--RTKIAELE---RQYPALDTEVASGHQGLE---NGVTASGD 720

Query: 964  AFHMEQLKYAEMRARQQHFQQMHQQQQQPPP-----ALPP-----GSQPIPPTGAAGPPA 1013
               +E L+  E   R     +    Q  P        LPP     G  P PP   +GP  
Sbjct: 721  VC-LEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQT 779

Query: 1014 VH----GLAVAPASV--------------VPAP-------AGSG----APPGSLGPSEQI 1044
                   L V+P  +               P P       AG G     PP S+    Q 
Sbjct: 780  KFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQT 839

Query: 1045 GQAGSTAG--------------PQQQQPAGAPQPGAVPPGVPP---------PGPHGPSP 1081
                S +               P  +  +  P  G VPP  PP         P    P P
Sbjct: 840  SHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQP 899

Query: 1082 FPNQQT-----PPSMMPGA-------VPGSG-HPGVADPGTPLPPDPTAPSPGTVTPVPP 1128
             P Q T     PP  +PGA       +PG+G  P    PG  +PP P  P PG   P PP
Sbjct: 900  PPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPP--PLPGAAIPPPP 957

Query: 1129 P 1129
            P
Sbjct: 958  P 958



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 52/170 (30%), Positives = 65/170 (38%), Gaps = 38/170 (22%)

Query: 989  QQQPPPAL-------PPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041
            Q  PPP+L        PGSQP P + +      H  +V+  S         +PP    P 
Sbjct: 809  QPPPPPSLLWSAGQGQPGSQP-PHSISTEFQTSHEHSVS--SAFKNSCNIPSPP----PL 861

Query: 1042 EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVP------PPG-------PHGPSPFPNQQ-T 1087
                 + S  G     P   P PG   P +P      PP        P  P P P     
Sbjct: 862  PCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIP 921

Query: 1088 PPSMMPGA-------VPGSGHPGVAD-PGTPLPPDPTAPSPGTVTPVPPP 1129
            PP  +PGA       +PG+G P     PG  +PP P  P PG   P+PPP
Sbjct: 922  PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPP--PLPGAGIPLPPP 969



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 17/162 (10%)

Query: 954  QRQQLLAD-RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPP 1012
            +++ LL+D +QA  ++Q        +QQ   Q+  QQQQ    L    +P  P  A  P 
Sbjct: 191  EQEDLLSDIQQAIRLQQ--------QQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQ 242

Query: 1013 AVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG---STAGPQQQQPAGAPQPGAVPP 1069
                L +    + P+  G+G  PGS    + +        +   + ++P   P PG +P 
Sbjct: 243  PGAFLGLDRFLLGPS-GGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPV 301

Query: 1070 GVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPL 1111
                  P  P+  P  +  PS      P +G PG    G P+
Sbjct: 302  S---EAPSLPAAQPAAKDSPSSTAFPFPEAG-PGEEAAGAPV 339


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 60/174 (34%), Positives = 71/174 (40%), Gaps = 38/174 (21%)

Query: 990  QQP----PPALPPGSQ--PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPG------- 1036
            QQP    PP  PPG+   P  P G A PPA    +  P+S  P P     PPG       
Sbjct: 344  QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403

Query: 1037 ----SLGPSEQIGQAGSTAG-PQQQQPAGAPQPGAVPPGVPPPGP-----HGPSPFPNQQ 1086
                +  P++Q+G     A  P  Q PA AP P   P   P PG       GP     QQ
Sbjct: 404  QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463

Query: 1087 T----PPSMMPGAV------PGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
            T    PPS +PG        PG   P    PG+  PP   +  PG+    PPPQ
Sbjct: 464  TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP---SQQPGSTK--PPPQ 512



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 46/144 (31%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 990  QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASV---VPAPAGSGAPPGSLGPSEQIGQ 1046
            QQP PA PP  Q   P   A  P +   A AP      V  P     P    GP +   Q
Sbjct: 403  QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 1047 AGSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVA 1105
                  P  Q P  A  P   P P  PPP   G +  P+QQ   +  P   PG   P   
Sbjct: 463  QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522

Query: 1106 DPGTPLPP--DPTAPSPGTVTPVP 1127
             PG+  PP   P +  P    P P
Sbjct: 523  QPGSTKPPSQQPGSAKPSAQQPSP 546



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 60/193 (31%), Positives = 71/193 (36%), Gaps = 46/193 (23%)

Query: 983  QQMHQQQQQPPPALPP--GSQPIPPTGAAGPPA--------------VHGLAVAPASVVP 1026
            QQ  + + QPP    P  G    P T  A  P               V G +V P+   P
Sbjct: 242  QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301

Query: 1027 APAGSGAPPGSLGPSEQIGQAGSTAGPQQQ--QPAG-----APQPGAVPPGVPPPG---- 1075
            +      P     P++Q G   S  GP +   QP+G     A QPG V P V PPG    
Sbjct: 302  SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361

Query: 1076 ---PHGPSPFPNQQT----PPSMMPGAV-----PGSGHPGVADPGTPLP-------PDPT 1116
               P GP+  P QQT    P S  PG       PG G      PG   P       P P 
Sbjct: 362  PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421

Query: 1117 APSPGTVTPVPPP 1129
            A  PG  +P   P
Sbjct: 422  AQQPGLQSPAKAP 434



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 49/139 (35%), Positives = 54/139 (38%), Gaps = 30/139 (21%)

Query: 990  QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            QQP PA PP  QP    G+A PP+       P S  P P      PG   PS Q  Q GS
Sbjct: 482  QQPGPAKPPPQQP----GSAKPPSQQ-----PGSTKPPP----QQPGPAKPSPQ--QPGS 526

Query: 1050 TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGT 1109
            T  P Q       QPG+  P    P P  PS         S  P +  GSG P    P T
Sbjct: 527  TKPPSQ-------QPGSAKPSAQQPSPAKPS------AQQSTKPVSQTGSGKP--LQPPT 571

Query: 1110 PLPPDPTAPSPGTVTPVPP 1128
              P     PS G    + P
Sbjct: 572  VSPSAKQPPSQGLPKTICP 590



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 17/120 (14%)

Query: 984  QMHQQQQQPPPALPPGSQP---IPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040
            Q   +++  PP     ++P    PPTG    P         +  +P PA         GP
Sbjct: 784  QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-------DSKAIPRPASDSKIISHPGP 836

Query: 1041 S------EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP-PSMMP 1093
            S      +Q+        P++ Q   +P+P A P     P P GP P   Q  P P   P
Sbjct: 837  SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 30/109 (27%), Positives = 38/109 (34%), Gaps = 22/109 (20%)

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            P+SV+  P             E  GQ      P  Q P+G+P   ++P   P P     S
Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEK----PASQLPSGSPSVSSLP-AKPRPFFRSSS 2398

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPP 1129
               + Q PP                 P  P PP P  P P    P+PPP
Sbjct: 2399 LDISAQPPP-----------------PPPPPPPPPPPPPPPPPPPLPPP 2430



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 7/74 (9%)

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PAS +P    SG+P  S  P++      S++     QP   P P   PP  PPP P  P 
Sbjct: 2372 PASQLP----SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP--PPPPPPPPP 2425

Query: 1081 PFPNQQTP-PSMMP 1093
            P P   +P P+++P
Sbjct: 2426 PLPPPTSPKPTILP 2439



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 33/139 (23%), Positives = 48/139 (34%), Gaps = 18/139 (12%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAG 1048
            QPPP  PP   P PP     PP +        +++P    + A P +      + +    
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE 2463

Query: 1049 STAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPG 1108
            +TA  +             PP VPP               PS +P  +  +  P  + P 
Sbjct: 2464 TTAVLRSNGLPVTRICTTAPPPVPP--------------KPSSIPSGLVFTHRPEPSKP- 2508

Query: 1109 TPLPPDPTAPSPGTVTPVP 1127
             P+ P P  P   T T  P
Sbjct: 2509 -PIAPKPVIPQLPTTTQKP 2526



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 35/163 (21%), Positives = 63/163 (38%), Gaps = 22/163 (13%)

Query: 717  PRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAG--- 773
            P   S       E+   + E +   + E  +++ +E  K T K D    + SS       
Sbjct: 1438 PHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS 1497

Query: 774  ------TTSDEP-ERIEESGNDE----------ARVEGQATDEKKEPKEPREGGGAIEEE 816
                  TT  EP + +EES   E            V   ++DE K+  E  +G G  E+ 
Sbjct: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ--EDSQGSGEEEDF 1555

Query: 817  AKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPK 859
             +++  E    ++  G E D    ++  +     + +K++E K
Sbjct: 1556 IRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK 1598



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 18/114 (15%)

Query: 1017 LAVAPASVVP----APAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVP 1072
            LA  P+S  P    AP  + +      P  Q       A P+Q   + AP+P   PP V 
Sbjct: 650  LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL-SKAPEPKKPPPLVK 708

Query: 1073 PPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPV 1126
             P  HG SP    + PP     + P              P +P+ PS     PV
Sbjct: 709  QPTLHG-SPSAKAKQPPEADSLSKPAP------------PKEPSVPSEQDKAPV 749


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 60/174 (34%), Positives = 71/174 (40%), Gaps = 38/174 (21%)

Query: 990  QQP----PPALPPGSQ--PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPG------- 1036
            QQP    PP  PPG+   P  P G A PPA    +  P+S  P P     PPG       
Sbjct: 344  QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403

Query: 1037 ----SLGPSEQIGQAGSTAG-PQQQQPAGAPQPGAVPPGVPPPGP-----HGPSPFPNQQ 1086
                +  P++Q+G     A  P  Q PA AP P   P   P PG       GP     QQ
Sbjct: 404  QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463

Query: 1087 T----PPSMMPGAV------PGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
            T    PPS +PG        PG   P    PG+  PP   +  PG+    PPPQ
Sbjct: 464  TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP---SQQPGSTK--PPPQ 512



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 46/144 (31%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 990  QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASV---VPAPAGSGAPPGSLGPSEQIGQ 1046
            QQP PA PP  Q   P   A  P +   A AP      V  P     P    GP +   Q
Sbjct: 403  QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 1047 AGSTAGPQQQQPAGAPQPGAVP-PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVA 1105
                  P  Q P  A  P   P P  PPP   G +  P+QQ   +  P   PG   P   
Sbjct: 463  QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522

Query: 1106 DPGTPLPP--DPTAPSPGTVTPVP 1127
             PG+  PP   P +  P    P P
Sbjct: 523  QPGSTKPPSQQPGSAKPSAQQPSP 546



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 60/193 (31%), Positives = 71/193 (36%), Gaps = 46/193 (23%)

Query: 983  QQMHQQQQQPPPALPP--GSQPIPPTGAAGPPA--------------VHGLAVAPASVVP 1026
            QQ  + + QPP    P  G    P T  A  P               V G +V P+   P
Sbjct: 242  QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301

Query: 1027 APAGSGAPPGSLGPSEQIGQAGSTAGPQQQ--QPAG-----APQPGAVPPGVPPPG---- 1075
            +      P     P++Q G   S  GP +   QP+G     A QPG V P V PPG    
Sbjct: 302  SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361

Query: 1076 ---PHGPSPFPNQQT----PPSMMPGAV-----PGSGHPGVADPGTPLP-------PDPT 1116
               P GP+  P QQT    P S  PG       PG G      PG   P       P P 
Sbjct: 362  PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421

Query: 1117 APSPGTVTPVPPP 1129
            A  PG  +P   P
Sbjct: 422  AQQPGLQSPAKAP 434



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 49/139 (35%), Positives = 54/139 (38%), Gaps = 30/139 (21%)

Query: 990  QQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            QQP PA PP  QP    G+A PP+       P S  P P      PG   PS Q  Q GS
Sbjct: 482  QQPGPAKPPPQQP----GSAKPPSQQ-----PGSTKPPP----QQPGPAKPSPQ--QPGS 526

Query: 1050 TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGT 1109
            T  P Q       QPG+  P    P P  PS         S  P +  GSG P    P T
Sbjct: 527  TKPPSQ-------QPGSAKPSAQQPSPAKPS------AQQSTKPVSQTGSGKP--LQPPT 571

Query: 1110 PLPPDPTAPSPGTVTPVPP 1128
              P     PS G    + P
Sbjct: 572  VSPSAKQPPSQGLPKTICP 590



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 17/120 (14%)

Query: 984  QMHQQQQQPPPALPPGSQP---IPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP 1040
            Q   +++  PP     ++P    PPTG    P         +  +P PA         GP
Sbjct: 784  QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-------DSKAIPRPASDSKIISHPGP 836

Query: 1041 S------EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP-PSMMP 1093
            S      +Q+        P++ Q   +P+P A P     P P GP P   Q  P P   P
Sbjct: 837  SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 30/109 (27%), Positives = 38/109 (34%), Gaps = 22/109 (20%)

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            P+SV+  P             E  GQ      P  Q P+G+P   ++P   P P     S
Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEK----PASQLPSGSPSVSSLP-AKPRPFFRSSS 2398

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPP 1129
               + Q PP                 P  P PP P  P P    P+PPP
Sbjct: 2399 LDISAQPPP-----------------PPPPPPPPPPPPPPPPPPPLPPP 2430



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 7/74 (9%)

Query: 1021 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS 1080
            PAS +P    SG+P  S  P++      S++     QP   P P   PP  PPP P  P 
Sbjct: 2372 PASQLP----SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP--PPPPPPPPP 2425

Query: 1081 PFPNQQTP-PSMMP 1093
            P P   +P P+++P
Sbjct: 2426 PLPPPTSPKPTILP 2439



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 33/139 (23%), Positives = 48/139 (34%), Gaps = 18/139 (12%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAG 1048
            QPPP  PP   P PP     PP +        +++P    + A P +      + +    
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE 2463

Query: 1049 STAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPG 1108
            +TA  +             PP VPP               PS +P  +  +  P  + P 
Sbjct: 2464 TTAVLRSNGLPVTRICTTAPPPVPP--------------KPSSIPSGLVFTHRPEPSKP- 2508

Query: 1109 TPLPPDPTAPSPGTVTPVP 1127
             P+ P P  P   T T  P
Sbjct: 2509 -PIAPKPVIPQLPTTTQKP 2526



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 35/163 (21%), Positives = 63/163 (38%), Gaps = 22/163 (13%)

Query: 717  PRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAG--- 773
            P   S       E+   + E +   + E  +++ +E  K T K D    + SS       
Sbjct: 1438 PHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS 1497

Query: 774  ------TTSDEP-ERIEESGNDE----------ARVEGQATDEKKEPKEPREGGGAIEEE 816
                  TT  EP + +EES   E            V   ++DE K+  E  +G G  E+ 
Sbjct: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ--EDSQGSGEEEDF 1555

Query: 817  AKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPK 859
             +++  E    ++  G E D    ++  +     + +K++E K
Sbjct: 1556 IRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETK 1598



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 18/114 (15%)

Query: 1017 LAVAPASVVP----APAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVP 1072
            LA  P+S  P    AP  + +      P  Q       A P+Q   + AP+P   PP V 
Sbjct: 650  LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL-SKAPEPKKPPPLVK 708

Query: 1073 PPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPV 1126
             P  HG SP    + PP     + P              P +P+ PS     PV
Sbjct: 709  QPTLHG-SPSAKAKQPPEADSLSKPAP------------PKEPSVPSEQDKAPV 749


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
            subunit [Homo sapiens]
          Length = 551

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 52/156 (33%), Positives = 60/156 (38%), Gaps = 19/156 (12%)

Query: 992  PPPALPPG-SQPIPPTGAAGPPAVHGLAVAPASVVPAPA------GSGAPPGSLGPSEQI 1044
            PPP  P G + P PP G  GPP   G    P  V+P P       G   PP  L P +  
Sbjct: 226  PPPPFPAGQTPPRPPLGPPGPPGPPG-PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF 284

Query: 1045 GQ---AGSTAGPQQQQPAGAPQPGAVPP--------GVPPPGPHGPSPFPNQQTPPSMMP 1093
            GQ        GP    P   P PG  PP        G  PP P GP   P    PP  +P
Sbjct: 285  GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLP 344

Query: 1094 GAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPP 1129
            G  PG+  P         PP   +  P + +  PPP
Sbjct: 345  GPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 53/152 (34%), Positives = 60/152 (39%), Gaps = 19/152 (12%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            P A+P G +   P G  GPP        P      P G   PPG   P + +      AG
Sbjct: 208  PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL--PPPLAG 265

Query: 1053 PQQQ------------QPAGAPQPGAVPPGVPPPGP-HG--PSPFPNQQTPPSMMPGAVP 1097
            P  +            QP G P  G +PPG PPP P +G  P P P QQ PP   PG  P
Sbjct: 266  PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPP-PPGPFP 324

Query: 1098 GSGHPGVADPGTPLPPDPTAPSPGTVTPVPPP 1129
                PG   P   L P P  P P    P P P
Sbjct: 325  -PRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 50/137 (36%), Positives = 56/137 (40%), Gaps = 20/137 (14%)

Query: 1007 GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA--PQP 1064
            G AGPP     A  P        G G  PG++   ++        GP    PAG   P+P
Sbjct: 184  GKAGPPGGSSRAAFPQG----GRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239

Query: 1065 GAVPPGVPPPGPHGPSPFPNQQTPPSMM---------PGAVPGSGHPGVADPGTPLPPDP 1115
               PPG  PPGP GP P P Q  PP +          P  V   G P    P  PLPP P
Sbjct: 240  PLGPPG--PPGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296

Query: 1116 TAPSPGTVTP--VPPPQ 1130
              P PG   P   PPPQ
Sbjct: 297  PPPVPGYGPPPGPPPPQ 313



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 43/126 (34%), Positives = 47/126 (37%), Gaps = 33/126 (26%)

Query: 992  PPPALPP-GSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            PPP +P  G  P PP    GPP        P    P P G   PP +L P          
Sbjct: 296  PPPPVPGYGPPPGPPPPQQGPPP------PPGPFPPRPPGPLGPPLTLAP---------- 339

Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPH-GPSPFPNQQTPPSMMPGAVPGSGHPGVADP-G 1108
                   P   P P   PPG PPP PH  P+ FP    PP+        S  P   DP G
Sbjct: 340  -------PPHLPGP---PPGAPPPAPHVNPAFFP----PPTNSGMPTSDSRGPPPTDPYG 385

Query: 1109 TPLPPD 1114
             P P D
Sbjct: 386  RPPPYD 391



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 40/130 (30%), Positives = 45/130 (34%), Gaps = 17/130 (13%)

Query: 992  PPPALPPGSQ----PIPPTGAAGPPAVHGLAVAPASVVPA-----PAGS--GAPPGSLGP 1040
            PPP L PG      P+ P     PP V G    P    P      P G     PPG LGP
Sbjct: 274  PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP 333

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPG--AVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPG 1098
               +       GP    P GAP P     P   PPP   G     ++  PP+   G  P 
Sbjct: 334  PLTLAPPPHLPGP----PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389

Query: 1099 SGHPGVADPG 1108
                    PG
Sbjct: 390  YDRGDYGPPG 399



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 32/92 (34%), Positives = 36/92 (39%), Gaps = 19/92 (20%)

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG 1100
            S +  Q+G  +G  +  P G     A P G       G   F          PGAVPG  
Sbjct: 171  SRKTTQSGQMSGEGKAGPPGGSSRAAFPQG-----GRGRGRF----------PGAVPGGD 215

Query: 1101 H-PGVADPGTPLPPDP---TAPSPGTVTPVPP 1128
              PG A PG P PP P   T P P    P PP
Sbjct: 216  RFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPP 247


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
          Length = 2524

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 78/357 (21%), Positives = 136/357 (38%), Gaps = 34/357 (9%)

Query: 786  GNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSD 845
            G  + + + Q   ++++ ++P       E++ KEK  EA K++E+   E D E   ++  
Sbjct: 491  GKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKT 550

Query: 846  GDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAK 905
             D   +   EKE    +    ++   S+G RK ++ R     +++  A +  A    ++ 
Sbjct: 551  DDTSGEDNDEKEAVASKG---RKTANSQGRRKGRITR-----SMANEANSEEAITPQQSA 602

Query: 906  HLAAVEERKIKSLVALLVETQMKKLEIKLRHFEEL------ETIMDREREALEYQRQQLL 959
             LA++E  +        +ET  K L    R++  +      +T+   +     Y+++Q L
Sbjct: 603  ELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNL 662

Query: 960  AD-RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLA 1018
             +  Q   ++  K    R +++       ++   PP +                 V    
Sbjct: 663  DEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAE 722

Query: 1019 VAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV-----PP 1073
               AS    P G  + P ++  S       S   P  +      Q G  PP       PP
Sbjct: 723  ALHASGNEVPRGECSGPATVNNS---SDTESIPSPHTEAAKDTGQNGPKPPATLGADGPP 779

Query: 1074 PGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
            PGP  P+P      PP  +P   P    P     G P PP P  PSP    PV P +
Sbjct: 780  PGP--PTP------PPEDIP--APTEPTPASEATGAPTPP-PAPPSPSAPPPVVPKE 825



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 130/633 (20%), Positives = 216/633 (34%), Gaps = 76/633 (12%)

Query: 545  QPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL----------------QTSASQQ 588
            Q   P+  Q + D K   K  E ++  PE    K +L                +  AS+ 
Sbjct: 509  QQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKG 568

Query: 589  MLNFPDKGKEK---PTDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALE 645
                  +G+ K      M N     +  T +     +    + +  WTE+E     + L 
Sbjct: 569  RKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLL 628

Query: 646  MYKDDWNKVSEHVGSRTQDEC---ILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGN 702
             +  +W+ ++  VGS+T  +C     ++ +    D  L+  +  +           ++  
Sbjct: 629  EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA 688

Query: 703  PVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKAD- 761
                  AF   V D  + ++      EE  +  E +  +  E    +    A V   +D 
Sbjct: 689  AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDT 748

Query: 762  ---PAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEP---REGGGAIEE 815
               P+   E++   G    +P     +            ++   P EP    E  GA   
Sbjct: 749  ESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTP 808

Query: 816  EAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGE 875
                 +  AP     K      EKE E +   P+ + E++K P    EE+  +  ++E  
Sbjct: 809  PPAPPSPSAPPPVVPK-----EEKEEETAAAPPVEEGEEQKPP--AAEELAVDTGKAEEP 861

Query: 876  RKTKVERDIGEG---NLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEI 932
             K++   +  EG        AA A A  A+KA+       R   +  +   +        
Sbjct: 862  VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATC 921

Query: 933  KLRHFEELETIMDREREALEYQRQQLLAD-----RQAFHMEQLKYAEMRARQQHFQQMHQ 987
                 +E E     ++  L   R  LL         A   + L   +++ R      +  
Sbjct: 922  SADEVDEAE---GGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVT 978

Query: 988  QQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            +  +PP      ++P PP   A PP  +   + P S  P   GS     S  P+      
Sbjct: 979  KVHEPPREDAAPTKPAPP---APPPPQN---LQPESDAPQQPGSSPRGKSRSPA------ 1026

Query: 1048 GSTAGPQQQQPAGAPQPGAVP---PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
               A  + ++P   P   A     PG PP    G  PFP    PP  +  A P +  P  
Sbjct: 1027 -PPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSG-LPFP---VPPREVIKASPHAPDPSA 1081

Query: 1105 ---ADPGTPLP------PDPTAPSPGTVTPVPP 1128
               A PG PLP        P  P P T++  PP
Sbjct: 1082 FSYAPPGHPLPLGLHDTARPVLPRPPTISNPPP 1114



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/102 (25%), Positives = 37/102 (36%), Gaps = 3/102 (2%)

Query: 305 PSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTK 364
           PSP  EA K   + GP  P T    G          +D+  P+      E T   T    
Sbjct: 752 PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPA 811

Query: 365 KDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQ 406
             S SAP     +   +E+E+E+      +E E       E+
Sbjct: 812 PPSPSAP---PPVVPKEEKEEETAAAPPVEEGEEQKPPAAEE 850


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 57/152 (37%), Positives = 65/152 (42%), Gaps = 23/152 (15%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP----GSLG--PSEQIGQ 1046
            PP    G+ P+PPTG +G P V     + A  VP    SGAPP    G  G  P    G 
Sbjct: 586  PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 645

Query: 1047 AGSTAGPQQQQPAGAPQP----GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGA--VPGSG 1100
            +G+   P        P P       PP VPP G  GP P      PP+   GA  VP +G
Sbjct: 646  SGAPPVPPTGDSGAPPVPPTGDSGAPP-VPPTGDAGPPP-----VPPTGDSGAPPVPPTG 699

Query: 1101 HPGVADPGTPLPPDPTAPSPGT----VTPVPP 1128
              G A P TP     TAP P T      PVPP
Sbjct: 700  DSG-APPVTPTGDSETAPVPPTGDSGAPPVPP 730



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 45/147 (30%), Positives = 53/147 (36%), Gaps = 13/147 (8%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP----GSLG--PSEQIGQ 1046
            P      + P+PPTG +    V     +  + VP    SGAPP    G  G  P    G 
Sbjct: 553  PTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 612

Query: 1047 AGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP-----GSGH 1101
            +G+   P        P P     G PP  P G S  P    PP+   GA P      SG 
Sbjct: 613  SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP--PVPPTGDSGAPPVPPTGDSGA 670

Query: 1102 PGVADPGTPLPPDPTAPSPGTVTPVPP 1128
            P V   G   PP           PVPP
Sbjct: 671  PPVPPTGDAGPPPVPPTGDSGAPPVPP 697



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 14/105 (13%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            PP    G+ P+PPTG AGPP V     + A  VP    SGAPP             +  G
Sbjct: 663  PPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPP------------VTPTG 710

Query: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHGPSPF-PNQQTPPSMMPGAV 1096
              +  P         PP VPP G    +P  P   +  + MP  +
Sbjct: 711  DSETAPVPPTGDSGAPP-VPPTGDSEAAPVPPTDDSKEAQMPAVI 754


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 104/457 (22%), Positives = 168/457 (36%), Gaps = 68/457 (14%)

Query: 731  FSKMKEEVPTALVEAHVRKVEEAAKVTG---KADPAFGLESSGIAGTTSDEPERIEE--- 784
            F+KM +E    +V      V    KV      +D +    S   + T   E ER +    
Sbjct: 454  FAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAE 513

Query: 785  ---------------SGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDE 829
                           S   + + + +  D+K++ KE  +    +EE  K K  E P K  
Sbjct: 514  LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKT 573

Query: 830  EKGKEGDS-----EKESEKSDGDPIVDPEKEKEPK----EGQEEVLKEVVESEGERKTKV 880
            +K    +S     E    KS   P  + E+E + K    E + ++  ++ +  GE+  +V
Sbjct: 574  KKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRV 633

Query: 881  ERDIG--EGNLSTAAAAALAAAAVKAKHLAAVE-ERKIKSLVALLVETQMKKLEI----- 932
               I   E +L  +    +       K     E ER + S +    + Q +K+++     
Sbjct: 634  VHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSS 693

Query: 933  KLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQP 992
            K++ F   E+    E  + + +     ++ +     + K    R +++H    HQQ QQ 
Sbjct: 694  KMKGFSSSESESSSESSSSDSED----SETEMAPKSKKKGHPGREQKKHHHHHHQQMQQA 749

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVP--------APAGSGAPPGSLGPSEQI 1044
            P  +P   QP PP     PP        P    P        APA   +PP  +     +
Sbjct: 750  PAPVP--QQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807

Query: 1045 ------GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ---TPPSMMPGA 1095
                  G      G   Q     PQP  +PP +P P  H   P  NQ    +PP++    
Sbjct: 808  LEPQLPGSVFDPIGHFTQPILHLPQP-ELPPHLPQPPEHSTPPHLNQHAVVSPPALHNAL 866

Query: 1096 VPGSGHPGVADPGTPLPPDPTAP---SPG-TVTPVPP 1128
                  P  ++    LPP P  P   SP  T TP+ P
Sbjct: 867  PQQPSRP--SNRAAALPPKPARPPAVSPALTQTPLLP 901



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 91/418 (21%), Positives = 156/418 (37%), Gaps = 59/418 (14%)

Query: 735  KEEVPTALVEAHVRKVEEA-----AKVTGKAD-PAFGLESSGIAGTTSD-EPERIEESGN 787
            K   P   V A  RK+++      AK+  + + P   + S  +   T    P    +S +
Sbjct: 431  KYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS 490

Query: 788  DEARVEGQATDEKKEPKEPREGGGAIEEEAK---EKTSEAPKKDEEKGKEGDSEKESEKS 844
            D +     +TD+ +E +  R     ++E+ K   E+ +   +  + K K+ + +K+ +K 
Sbjct: 491  DSSSDSDSSTDDSEEERAQRLA--ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKK 548

Query: 845  DGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKA 904
                    EK K  KE  EE  K   +    +KTK      + N S +  +    A +K+
Sbjct: 549  --------EKHKR-KEEVEENKKSKAKEPPPKKTK------KNNSSNSNVSKKEPAPMKS 593

Query: 905  KHLAAVE-ERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQ 963
            K     E E + K       E +   L+I     E+L  ++    ++ E   +    D  
Sbjct: 594  KPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVV-HIIQSREPSLKNSNPDEI 652

Query: 964  AFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPAS 1023
                E LK + +R  +++     +++++P        Q       AG   + G + + + 
Sbjct: 653  EIDFETLKPSTLRELERYVTSCLRKKRKP--------QAEKVDVIAGSSKMKGFSSSESE 704

Query: 1024 VVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQ-----------QQQPAGAPQPGAVPPGVP 1072
                 + S +       + +  + G     Q           QQ PA  PQ    PP  P
Sbjct: 705  SSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQP 764

Query: 1073 PPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
            PP P    P   QQ PP   P ++P    P +       PP    P   T  PV  PQ
Sbjct: 765  PPPP---PPQQQQQPPPPPPPPSMPQQAAPAMKSS----PP----PFIATQVPVLEPQ 811



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 48/176 (27%), Positives = 56/176 (31%), Gaps = 28/176 (15%)

Query: 981  HFQQ--MHQQQQQPPPALP-PGSQPIPPT----GAAGPPAVHGLAVAPASVVPAPAGSGA 1033
            HF Q  +H  Q + PP LP P     PP         PPA+H  A+      P+   +  
Sbjct: 822  HFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHN-ALPQQPSRPSNRAAAL 880

Query: 1034 PPGSLGP---SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVP-----------------P 1073
            PP    P   S  + Q      P   QP         PP  P                 P
Sbjct: 881  PPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQP 940

Query: 1074 PGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPP 1129
            P P  PS     Q PP + P   P         P  P PP P  P      P P P
Sbjct: 941  PTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP 996



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 44/159 (27%), Positives = 52/159 (32%), Gaps = 28/159 (17%)

Query: 992  PPPALPPGSQP-------IPPTGAAGPPAVHGLAVAPASVVPAPAGSGA----------- 1033
            P PA PP   P       +P    A PP V    +      PAP  +             
Sbjct: 882  PKPARPPAVSPALTQTPLLPQPPMAQPPQV----LLEDEEPPAPPLTSMQMQLYLQQLQK 937

Query: 1034 --PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSM 1091
              PP  L PS ++        P    P+   Q    PP  PPP P  P   P QQ  P  
Sbjct: 938  VQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPP---PQQQHQPPP 994

Query: 1092 MPGAV-PGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPP 1129
             P  + P      +  P  P    P  P PG   P P P
Sbjct: 995  RPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 48/196 (24%), Positives = 73/196 (37%), Gaps = 38/196 (19%)

Query: 955  RQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGA------ 1008
            +QQ     +  H++ ++++       H QQ    Q Q PP  PPG QP PP  A      
Sbjct: 987  QQQHQPPPRPVHLQPMQFST------HIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVI 1040

Query: 1009 ----------AGPPAVHGLAVAPAS-VVPAPAGS--------GAPPGSLGPSEQIGQAGS 1049
                      + P +   L  AP+  ++ +P  S          P  ++ P +Q  +A S
Sbjct: 1041 QHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAAS 1100

Query: 1050 TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS--PFPNQQTPPSMMPGAVPGSGHPGVADP 1107
               P   QP    +   +   +    P  PS  P P +       P  +P        D 
Sbjct: 1101 VVQP---QPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDV 1157

Query: 1108 GTPL--PPDPTAPSPG 1121
            G P+  PP+  AP PG
Sbjct: 1158 GRPVIRPPEQNAPPPG 1173



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 43/146 (29%), Positives = 51/146 (34%), Gaps = 31/146 (21%)

Query: 1016 GLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQ--------QQPAGA---PQP 1064
            G A    S VP    +  PP +  P        +T  P          Q P      PQP
Sbjct: 187  GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246

Query: 1065 GAVPPGVP--PPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV---ADPGTP--------- 1110
               PP VP  P  P  P+P P Q  PP +     P     GV   AD  TP         
Sbjct: 247  LQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP 306

Query: 1111 --LPPDPTAPSPG----TVTPVPPPQ 1130
              LPP+P     G    +  PV PP+
Sbjct: 307  PSLPPEPKTTKLGQRRESSRPVKPPK 332



 Score = 38.5 bits (88), Expect = 0.036
 Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 18/151 (11%)

Query: 846  GDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAA-----LAAA 900
            G P++ P ++  P  G  +  K+  + E +     ++D+   N+ + A+         ++
Sbjct: 1158 GRPVIRPPEQNAPPPGAPD--KDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSS 1215

Query: 901  AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
              K+   +  + R+     A   E + K L+ +  H E       +E+E L  +R +   
Sbjct: 1216 TAKSSSDSFEQFRR----AAREKEEREKALKAQAEHAE-------KEKERLRQERMRSRE 1264

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQ 991
            D  A    +  + E R RQ+  QQ  Q+QQQ
Sbjct: 1265 DEDALEQARRAHEEARRRQEQQQQQRQEQQQ 1295



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 41/147 (27%), Positives = 46/147 (31%), Gaps = 27/147 (18%)

Query: 984  QMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQ 1043
            Q   QQQ PPP  PP  QP P      PP                      P  L P + 
Sbjct: 967  QQQLQQQPPPPP-PPQPQPPPQQQHQPPPR---------------------PVHLQPMQF 1004

Query: 1044 IGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPG 1103
                     PQ QQP   P PG  P   PPP P  P         P         +GH  
Sbjct: 1005 STHIQQPPPPQGQQPP-HPPPGQQP---PPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLR 1060

Query: 1104 VADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
             A P   +   P      ++T   PPQ
Sbjct: 1061 EA-PSPLMIHSPQMSQFQSLTHQSPPQ 1086



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 28/123 (22%), Positives = 48/123 (39%), Gaps = 10/123 (8%)

Query: 282 NSPDSDRRDKKGGNYKKRKRSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTK 341
           N P    +DKK    +K KR        E KK  AK+ P     K+   +    +++   
Sbjct: 534 NKPKKKEKDKKEKKKEKHKRK---EEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAP 590

Query: 342 DMDEPSPVPNVEEVTLPKTVNTKK------DSESAP-VKGGTMTDLDEQEDESMETTGKD 394
              +P P    EE    K ++ ++      D    P  K G +  + +  + S++ +  D
Sbjct: 591 MKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPD 650

Query: 395 EDE 397
           E E
Sbjct: 651 EIE 653


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 55/166 (33%), Positives = 62/166 (37%), Gaps = 30/166 (18%)

Query: 989  QQQPPPALPPGSQPIPPT----GAAGPPAVHGLA--VAPASVVPAPAGSGAP--PGSLGP 1040
            Q  P P   PG Q  P      G  GPP + GL   + P          G P  PG LGP
Sbjct: 422  QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSM--------- 1091
                G+ G       Q P G P  G     + PPG  GP   P    PP           
Sbjct: 482  K---GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVA 538

Query: 1092 -------MPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
                    PGA+   G PG+  PG P PP P  P P  + P PPPQ
Sbjct: 539  GLHGPPGKPGALGPQGQPGL--PGPPGPPGPPGP-PAVMPPTPPPQ 581



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 44/142 (30%), Positives = 53/142 (37%), Gaps = 26/142 (18%)

Query: 991  QPPPALPPGSQPIP-PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            QP P    G + +P P G  GP    G  +  A  V  P G   PPG +G    +G+ G 
Sbjct: 218  QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG-LPGVGKPGV 276

Query: 1050 TAGPQQQQPAGAP----QPGAV----------PPGVPPPGPHGPSPFPNQQTPPSMM--- 1092
            T  P  Q P G P    +PG            PPG+P  G  G    P Q   P      
Sbjct: 277  TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQ 336

Query: 1093 -------PGAVPGSGHPGVADP 1107
                   P  +PG G PG   P
Sbjct: 337  GLPGLPGPPGLPGIGKPGFPGP 358



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 50/161 (31%), Positives = 59/161 (36%), Gaps = 23/161 (14%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG---PSEQIGQA 1047
            +P P  PPG   +P  G  G     G    P    P   G    PG++G      +IGQ 
Sbjct: 125  EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184

Query: 1048 GSTAGPQQQQPAGAPQPGAVP-------PGVP----PPGPHGPSPFPNQQ-------TPP 1089
            G         P G P P  +P       PG+P    P G  GP   P  Q          
Sbjct: 185  GEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244

Query: 1090 SMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
              MPGA    G PG+  P  P+   P    PG VT  P PQ
Sbjct: 245  FGMPGAPGVKGPPGMHGPPGPVGL-PGVGKPG-VTGFPGPQ 283



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 48/147 (32%), Positives = 51/147 (34%), Gaps = 43/147 (29%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            P P  PPG   +P  G  G P + G         P P G   P G  GP    G  G   
Sbjct: 193  PGPQGPPGPHGLPGIGKPGGPGLPGQ--------PGPKGDRGPKGLPGPQGLRGPKGDK- 243

Query: 1052 GPQQQQPAGAPQPGAVPPGVP-PPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV------ 1104
                    G   PGA  PGV  PPG HGP             P  +PG G PGV      
Sbjct: 244  --------GFGMPGA--PGVKGPPGMHGPPG-----------PVGLPGVGKPGVTGFPGP 282

Query: 1105 ----ADPGTPLPPDPTAP--SPGTVTP 1125
                  PG P  P P  P   PG   P
Sbjct: 283  QGPLGKPGAPGEPGPQGPIGVPGVQGP 309



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 51/148 (34%), Positives = 56/148 (37%), Gaps = 14/148 (9%)

Query: 988  QQQQPPPALPP---GSQPIPPTGAAGP---PAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041
            Q  Q PP +P     S PI P G  GP   P + G    P    P  AG   PPG  G  
Sbjct: 491  QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGAL 550

Query: 1042 EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPP-GPHGPS-PFPNQQTPPSMMPGAVPG- 1098
               GQ G    P    P G P P AV P  PPP G + P          P    GA  G 
Sbjct: 551  GPQGQPGLPGPPG---PPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGK 607

Query: 1099 SGHPGVADPGTPLPPDPTAPSPGTVTPV 1126
            +G P    P      + TAP P    PV
Sbjct: 608  NGGPAYEMPA--FTAELTAPFPPVGAPV 633



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 42/139 (30%), Positives = 48/139 (34%), Gaps = 19/139 (13%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGP 1053
            P  P G       G  GPP + G+            G G  PG+LGP    G+ G    P
Sbjct: 327  PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPR---GEKGPIGAP 383

Query: 1054 QQQQPAGAPQPGAVPPGVPP------PGPHGPSPFPNQQTPPSMMPGAVPG-SGHPG--- 1103
                P G P    +P  + P      PGP G       Q PP   P   PG  G PG   
Sbjct: 384  GIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPG--PKGEPGLQGFPGKPG 441

Query: 1104 ----VADPGTPLPPDPTAP 1118
                V  PG    P P  P
Sbjct: 442  FLGEVGPPGMRGLPGPIGP 460



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 50/176 (28%), Positives = 60/176 (34%), Gaps = 39/176 (22%)

Query: 991  QPPPALPPGSQPIPPTGAAGPP---AVHGLAVAPASVVPAPAGSGAP--PGSLGPSEQIG 1045
            Q PP +PP      P G   P    A  GLA+    +     G   P  P  +   +   
Sbjct: 39   QIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGK-EMPHLQYGKEYPHLPQYMKEIQPAP 97

Query: 1046 QAGSTAGPQ------------QQQPAGAPQPGAVP--PGVPP------PGPHGPSPFPNQ 1085
            + G  A P+            +Q P G P P   P  PG+P        G  GP  +P  
Sbjct: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157

Query: 1086 QTP--PSM--------MPGAVPGSGHPGVADP-GTPLPPDPTAPS--PGTVTPVPP 1128
              P  P M        MPGA    G  G   P G P P  P  P   PG   P  P
Sbjct: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP 213


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 55/166 (33%), Positives = 62/166 (37%), Gaps = 30/166 (18%)

Query: 989  QQQPPPALPPGSQPIPPT----GAAGPPAVHGLA--VAPASVVPAPAGSGAP--PGSLGP 1040
            Q  P P   PG Q  P      G  GPP + GL   + P          G P  PG LGP
Sbjct: 422  QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSM--------- 1091
                G+ G       Q P G P  G     + PPG  GP   P    PP           
Sbjct: 482  K---GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVA 538

Query: 1092 -------MPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
                    PGA+   G PG+  PG P PP P  P P  + P PPPQ
Sbjct: 539  GLHGPPGKPGALGPQGQPGL--PGPPGPPGPPGP-PAVMPPTPPPQ 581



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 44/142 (30%), Positives = 53/142 (37%), Gaps = 26/142 (18%)

Query: 991  QPPPALPPGSQPIP-PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS 1049
            QP P    G + +P P G  GP    G  +  A  V  P G   PPG +G    +G+ G 
Sbjct: 218  QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG-LPGVGKPGV 276

Query: 1050 TAGPQQQQPAGAP----QPGAV----------PPGVPPPGPHGPSPFPNQQTPPSMM--- 1092
            T  P  Q P G P    +PG            PPG+P  G  G    P Q   P      
Sbjct: 277  TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQ 336

Query: 1093 -------PGAVPGSGHPGVADP 1107
                   P  +PG G PG   P
Sbjct: 337  GLPGLPGPPGLPGIGKPGFPGP 358



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 50/161 (31%), Positives = 59/161 (36%), Gaps = 23/161 (14%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG---PSEQIGQA 1047
            +P P  PPG   +P  G  G     G    P    P   G    PG++G      +IGQ 
Sbjct: 125  EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184

Query: 1048 GSTAGPQQQQPAGAPQPGAVP-------PGVP----PPGPHGPSPFPNQQ-------TPP 1089
            G         P G P P  +P       PG+P    P G  GP   P  Q          
Sbjct: 185  GEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244

Query: 1090 SMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
              MPGA    G PG+  P  P+   P    PG VT  P PQ
Sbjct: 245  FGMPGAPGVKGPPGMHGPPGPVGL-PGVGKPG-VTGFPGPQ 283



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 48/147 (32%), Positives = 51/147 (34%), Gaps = 43/147 (29%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            P P  PPG   +P  G  G P + G         P P G   P G  GP    G  G   
Sbjct: 193  PGPQGPPGPHGLPGIGKPGGPGLPGQ--------PGPKGDRGPKGLPGPQGLRGPKGDK- 243

Query: 1052 GPQQQQPAGAPQPGAVPPGVP-PPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV------ 1104
                    G   PGA  PGV  PPG HGP             P  +PG G PGV      
Sbjct: 244  --------GFGMPGA--PGVKGPPGMHGPPG-----------PVGLPGVGKPGVTGFPGP 282

Query: 1105 ----ADPGTPLPPDPTAP--SPGTVTP 1125
                  PG P  P P  P   PG   P
Sbjct: 283  QGPLGKPGAPGEPGPQGPIGVPGVQGP 309



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 51/148 (34%), Positives = 56/148 (37%), Gaps = 14/148 (9%)

Query: 988  QQQQPPPALPP---GSQPIPPTGAAGP---PAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041
            Q  Q PP +P     S PI P G  GP   P + G    P    P  AG   PPG  G  
Sbjct: 491  QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGAL 550

Query: 1042 EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPP-GPHGPS-PFPNQQTPPSMMPGAVPG- 1098
               GQ G    P    P G P P AV P  PPP G + P          P    GA  G 
Sbjct: 551  GPQGQPGLPGPPG---PPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGK 607

Query: 1099 SGHPGVADPGTPLPPDPTAPSPGTVTPV 1126
            +G P    P      + TAP P    PV
Sbjct: 608  NGGPAYEMPA--FTAELTAPFPPVGAPV 633



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 42/139 (30%), Positives = 48/139 (34%), Gaps = 19/139 (13%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGP 1053
            P  P G       G  GPP + G+            G G  PG+LGP    G+ G    P
Sbjct: 327  PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPR---GEKGPIGAP 383

Query: 1054 QQQQPAGAPQPGAVPPGVPP------PGPHGPSPFPNQQTPPSMMPGAVPG-SGHPG--- 1103
                P G P    +P  + P      PGP G       Q PP   P   PG  G PG   
Sbjct: 384  GIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPG--PKGEPGLQGFPGKPG 441

Query: 1104 ----VADPGTPLPPDPTAP 1118
                V  PG    P P  P
Sbjct: 442  FLGEVGPPGMRGLPGPIGP 460



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 50/176 (28%), Positives = 60/176 (34%), Gaps = 39/176 (22%)

Query: 991  QPPPALPPGSQPIPPTGAAGPP---AVHGLAVAPASVVPAPAGSGAP--PGSLGPSEQIG 1045
            Q PP +PP      P G   P    A  GLA+    +     G   P  P  +   +   
Sbjct: 39   QIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGK-EMPHLQYGKEYPHLPQYMKEIQPAP 97

Query: 1046 QAGSTAGPQ------------QQQPAGAPQPGAVP--PGVPP------PGPHGPSPFPNQ 1085
            + G  A P+            +Q P G P P   P  PG+P        G  GP  +P  
Sbjct: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157

Query: 1086 QTP--PSM--------MPGAVPGSGHPGVADP-GTPLPPDPTAPS--PGTVTPVPP 1128
              P  P M        MPGA    G  G   P G P P  P  P   PG   P  P
Sbjct: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP 213


>gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]
          Length = 828

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 55/208 (26%), Positives = 91/208 (43%), Gaps = 37/208 (17%)

Query: 324 YTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQ 383
           ++KS RG  + E++D T    E         +TL     +  D +S         +L++Q
Sbjct: 272 FSKSSRGCLQNEKQDETLSSSE---------ITLWTEKQSNGDKKSI--------ELNDQ 314

Query: 384 EDESMETTGKDEDENSTGNKGEQTKNPD--------------LHEDNVTEQTHH---III 426
           +   +       D         Q  +P+               H   + E++H    +  
Sbjct: 315 KFNELIKNCNKHDGRGIIVDARQLPSPEPCEIQKNLNDNEMLFHSCQMVEESHEEEELKP 374

Query: 427 PSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTAC 486
           P      D N +   E++A+PEFF G+ ++KTPE YL  RN+++D + +   +YL  T+ 
Sbjct: 375 PEQEIEIDRNIIQEEEKQAIPEFFEGR-QAKTPERYLKIRNYILDQWEICKPKYLNKTSV 433

Query: 487 RRNL--AGDVCAIMRVHAFLEQWGLINY 512
           R  L   GDV  I R+H +LE  G IN+
Sbjct: 434 RPGLKNCGDVNCIGRIHTYLELIGAINF 461



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 14/37 (37%), Positives = 22/37 (59%)

Query: 626 ASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSRT 662
           AS + +WT +E  L  + L  +   W K+S+ +GSRT
Sbjct: 115 ASYSVKWTIEEKELFEQGLAKFGRRWTKISKLIGSRT 151


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 50/144 (34%), Positives = 59/144 (40%), Gaps = 21/144 (14%)

Query: 992  PPPALPPGSQPIP----PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PP A PP  +  P    P  A  PPA    +       P+P G+  PP +  PS +    
Sbjct: 942  PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK---- 997

Query: 1048 GSTAGPQQQQPAGAPQPGAVPPGVPPPGPHG---PSPFP-NQQTPPSMMPGAVPGSGHPG 1103
                GP    P GAP     PP V PP P G    +PFP    TPP+  P +  GS    
Sbjct: 998  ---GGPATPSPKGAP----TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT 1050

Query: 1104 VADPGTPLPPDPTAPSP--GTVTP 1125
                G P  P  T PSP  G  TP
Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATP 1074



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 57/169 (33%), Positives = 65/169 (38%), Gaps = 41/169 (24%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGS--------GAP--PGSLGPSE 1042
            PPA+ P   P P    A  P   G +  PA+  P+P GS        GAP  P +  PS 
Sbjct: 1011 PPAVTP---PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067

Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS----PFPNQQTPPS-------- 1090
            +        GP      GAP P A  P  P  GP  PS    P P   TPPS        
Sbjct: 1068 K-------GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120

Query: 1091 ------MMPGAVPGSGHPGVADP---GTPLPPDPTAPSPGTVTPVPPPQ 1130
                    P A P S   G+A P   G P  P  T PSP      PPP+
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 54/171 (31%), Positives = 66/171 (38%), Gaps = 39/171 (22%)

Query: 992  PPPALP--PGSQPIPPTGAAGPPAVHGLAVAPASV---------VPAPAGSGAPPGSLGP 1040
            PP   P  P + P  P G    P+  G    PA+           P+P G+   P +  P
Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226

Query: 1041 SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGP----SPFPNQQTPPSMMPG-A 1095
            S +    G  A P    P GAP   A  P  P  GP  P    +P P   TPPS+  G A
Sbjct: 1227 SPK----GGLATP---SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279

Query: 1096 VP---GSGHPGVADP-------------GTPLPPDPTAPSPGTVTPVPPPQ 1130
             P   G+ +P V  P             G P PP  T PSP      PPP+
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 50/149 (33%), Positives = 59/149 (39%), Gaps = 27/149 (18%)

Query: 992  PPPALPPGSQPIP----PTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047
            PP A PP  +  P    P GA  PPA    +       P+P G+  PP    PS +    
Sbjct: 965  PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK---- 1020

Query: 1048 GSTAGPQQQQPAGAPQP--GAVPPGVPPPGPHG-----PSPFPNQQTPPSMMPGAVPGSG 1100
            GS        PA  P P   + PP   PP P G     P P     TP + +P    G  
Sbjct: 1021 GS--------PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA 1072

Query: 1101 HPGVADPGTPLPPDPTAPSP--GTVTPVP 1127
             P +   G P PP  T PSP  G  TP P
Sbjct: 1073 TPSL--KGAPTPPAATPPSPKGGPATPSP 1099



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 51/158 (32%), Positives = 63/158 (39%), Gaps = 27/158 (17%)

Query: 996  LPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGS-------GAP--PGSLGPSEQIGQ 1046
            +PP + P  P G    P   G    PA+  P+P G        GAP  P +  PS + G 
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163

Query: 1047 A-----GSTAGPQQQQPA-----GAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSMMPG 1094
            A     G+   P    P+       P P   P  P   PP P G    P+ +  P+  P 
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT-PA 1222

Query: 1095 AVPGSGHPGVADP---GTPLPPDPTAPSP--GTVTPVP 1127
            A P S   G+A P   G P  P  T PSP  G  TP P
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 49/152 (32%), Positives = 59/152 (38%), Gaps = 19/152 (12%)

Query: 986  HQQQQQPPPALPP----GSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS 1041
            H+     P A PP    G    PP GA   PA    +       P P G+   P +  PS
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 1042 EQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGH 1101
             +    G  A P    P GAP      P   PP P G    P+ +  P+  P A P S  
Sbjct: 1182 PK----GGLATP---SPKGAP----TTPAATPPSPKGGLATPSPKGAPT-TPAATPPSPK 1229

Query: 1102 PGVADP---GTPLPPDPTAPSPGTVTPVPPPQ 1130
             G+A P   G P  P  T PSP      PPP+
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 53/152 (34%), Positives = 62/152 (40%), Gaps = 15/152 (9%)

Query: 992  PPPALPPGSQ---PIPPTGAAGP-----PAVHGLAVAP--ASVVPAPAGSGAPPGSLG-P 1040
            PP   P  S    P P  G A P     PA+   + +P  A   PAP G  A P   G P
Sbjct: 881  PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940

Query: 1041 SEQIGQAGS-TAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1099
            +       S   GP    P  AP P A  P  P  GP  PSP     TPP+  P + P  
Sbjct: 941  TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP-KGAPTPPAATPPS-PKG 998

Query: 1100 GHPGVADPGTPLPPDPTAPSP-GTVTPVPPPQ 1130
            G    +  G P PP  T PSP G+    P P+
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 52/164 (31%), Positives = 61/164 (37%), Gaps = 26/164 (15%)

Query: 988  QQQQPPPALPPGSQPIPPTGAAGPPAVHGLA----VAPASVVPAPAGSGAPPGSLGP--- 1040
            Q  +  PA      P  P GA  P AV  L+      P    P P+    P    GP   
Sbjct: 844  QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903

Query: 1041 -----------SEQIGQAGSTAGPQ----QQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQ 1085
                       S    +A +T  P+       P GAP P A  P  P  GP  PSP    
Sbjct: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP-KWA 962

Query: 1086 QTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSP--GTVTPVP 1127
             TPP+  P + P  G    +  G P PP  T PSP  G  TP P
Sbjct: 963  PTPPAATPPS-PKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 48/153 (31%), Positives = 54/153 (35%), Gaps = 16/153 (10%)

Query: 993  PPALPPGSQPIPPTGAAGPPAV------HGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQ 1046
            PP+   G    PP GA  PPA        GLA  P    P PA    P    GP+    +
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307

Query: 1047 AGST----AGPQQQQPAGAPQP--GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSG 1100
               T      P  +   G P P     PP V PP P G    P   TP S      P S 
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP-ATTPSSKGGPTTPSSK 1366

Query: 1101 H---PGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
                P  A P     P  T PSP     +P P+
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 48/146 (32%), Positives = 55/146 (37%), Gaps = 24/146 (16%)

Query: 1004 PPT--GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA 1061
            PPT  G+AGP    G   +P S V A   S  P  SL          +T  P    P GA
Sbjct: 808  PPTKKGSAGPDTPIGNLSSPVSPVEA---SFLPENSLSFQGSKDSPATTHSPTPPSPKGA 864

Query: 1062 PQPGAV----PPGVPPPGPHGPS------PFPNQ--------QTPPSMMPGAVPGSGHPG 1103
            P P AV    P GV  P    P+      PFP +        Q P   M  + P      
Sbjct: 865  PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARAT 924

Query: 1104 VADPGTPLPPDPT-APSPGTVTPVPP 1128
             A  G P  P P  AP+P   TP  P
Sbjct: 925  PAPKGIPASPSPKGAPTPPAATPPSP 950



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 48/170 (28%), Positives = 62/170 (36%), Gaps = 34/170 (20%)

Query: 992  PPPALPPGSQPIP----PTGAAGPPAV-----HGLAVAPASVVPAPAGSGAPPGSLGPSE 1042
            PP A PP  +  P    P GA  PPAV      G    PA+   +  G   P    GP+ 
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371

Query: 1043 QIGQAGSTAGPQQQQPA-----------GAPQPGAVPPGVPPPGPHGP-------SPFPN 1084
                     GP    P+           G P   AV P  P   P  P       +P   
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKG 1431

Query: 1085 QQTPPSMMPGAVPGSGHPGVADP-GTPLPP----DPTAPSPGTVTPVPPP 1129
              TPP++ P ++  +  P  + P G P  P    DPT P+    +P  PP
Sbjct: 1432 DLTPPAVTPVSLKKA--PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 48/146 (32%), Positives = 60/146 (41%), Gaps = 35/146 (23%)

Query: 994  PALP-PGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            PA P P   P PP  AA PP+  G    PA+  P+P  +  PP +  PS +        G
Sbjct: 931  PASPSPKGAPTPP--AATPPSPKG---GPAT--PSPKWAPTPPAATPPSPK-------GG 976

Query: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHGPSP-----FPNQQ---TPPSMMPGAVPGSGHPGV 1104
            P    P GAP P         P    PSP      P+ +   TPP++ P +  GS     
Sbjct: 977  PATPSPKGAPTP---------PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP 1027

Query: 1105 ADPGTPLPPDPTAPSP---GTVTPVP 1127
               G   PP  T PSP      TP+P
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLP 1053



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 37/141 (26%), Positives = 50/141 (35%), Gaps = 14/141 (9%)

Query: 1004 PPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLG-----------PSEQIG--QAGST 1050
            P  G   PPAV  +++  A    AP G  A P S G           P E     Q  ++
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487

Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTP 1110
            + P++     AP      P V P  P      P+ +  P      +     P    P   
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547

Query: 1111 L-PPDPTAPSPGTVTPVPPPQ 1130
            L PP  T PSP     +P P+
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPK 1568



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 43/146 (29%), Positives = 55/146 (37%), Gaps = 19/146 (13%)

Query: 994  PALPPGSQ-PIPPTGAA------GPPAVHGLAVAPASVVPAPAGSGAPP----GSLGPSE 1042
            PA P   + PI PT            A     + PA  VP+P  + A P        PS 
Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS 1576

Query: 1043 QIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHP 1102
            +   +     P   + A +P+   +PP V  P P   +P P   TPPS      P  G  
Sbjct: 1577 KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK-EAPTPPAVTPPS------PEKGPA 1629

Query: 1103 GVADPGTPLPPDPTAPSPGTVTPVPP 1128
              A  GTP  P P  PS    +P  P
Sbjct: 1630 TPAPKGTPTSP-PVTPSSLKDSPTSP 1654



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 43/169 (25%), Positives = 57/169 (33%), Gaps = 35/169 (20%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSL--GPSEQIGQAGSTA 1051
            P LP  + P P    A        +   A   PAP G+   P  +   P E      S  
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524

Query: 1052 GP--------QQQQPAG-APQPGAVPPGVPPPGPHGPSPFPNQQ------------TPPS 1090
             P         ++ PA  AP+   +PP +  P P      P  +            +PP+
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584

Query: 1091 MMPGAVPGSGHP-------GVADPG---TPLPPDPTAPSP--GTVTPVP 1127
            + P    G+  P        V  P     P PP  T PSP  G  TP P
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 36/136 (26%), Positives = 46/136 (33%), Gaps = 21/136 (15%)

Query: 994  PALPPGSQP--IPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            P+    S P  + P+   G P+   L + PA   P+P  +  PP    PS +        
Sbjct: 1574 PSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE-------K 1626

Query: 1052 GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPL 1111
            GP    P G P    V P      P  P+      +    M   VP       A  G P 
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPA------SVTCKMGATVP------QASKGLPA 1674

Query: 1112 PPDPTAPSPGTVTPVP 1127
               PTA     V P P
Sbjct: 1675 KKGPTALKEVLVAPAP 1690



 Score = 37.7 bits (86), Expect = 0.062
 Identities = 44/177 (24%), Positives = 63/177 (35%), Gaps = 42/177 (23%)

Query: 994  PALPPGSQPIP----PTGAAGPPAVHGLAVAPASVVPAPA--GSGAPPGSL---GPSEQI 1044
            P +P  S+  P    P     P A   LA      VP+P+   +G PPG+    G S   
Sbjct: 699  PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758

Query: 1045 GQAGSTAGPQQ------QQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPG 1098
              A   + P++         A A   G +      P P G S  P  + PP+    A P 
Sbjct: 759  ALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818

Query: 1099 SGHPGVADPGTPL--------------------------PPDPT-APSPGTVTPVPP 1128
            +    ++ P +P+                          PP P  AP+P  VTP+ P
Sbjct: 819  TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSP 875


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 71/265 (26%), Positives = 107/265 (40%), Gaps = 47/265 (17%)

Query: 903  KAKHLAAVEERKIKSLVALLVETQ--MKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            K++  AA  E+K+ S +    E Q  MKK+E     FE+    +  E++AL  ++QQ+  
Sbjct: 467  KSEAKAAELEKKLDSELTARHELQVEMKKME---SDFEQKLQDLQGEKDALHSEKQQIAT 523

Query: 961  DRQAFHMEQLKYA--------EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPT----GA 1008
            ++Q    E  +          E+   ++    +       PP++P  + P+PP     G 
Sbjct: 524  EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA-PVPPAPPLPGD 582

Query: 1009 AG----PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA------------- 1051
            +G    PP   G +  P    P P      PG +  S      G TA             
Sbjct: 583  SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 642

Query: 1052 --GPQQQQPAGAPQPGAVPPG--VPPPGP-HGPSPFPNQQTPPSMMPGA--VPGSGHPGV 1104
               P   +  G P P ++P G  +PPP P  G +  P    PP  +PG+  +P    P  
Sbjct: 643  PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP---PPPPPLPGSAGIPPPPPPLP 699

Query: 1105 ADPGTPLPPDPTAPSPGTVTPVPPP 1129
             + G P PP P    PG   P PPP
Sbjct: 700  GEAGMPPPPPPLPGGPG--IPPPPP 722



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 52/145 (35%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 992  PPPALPPG----SQPIPPTGAA--GPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQI 1044
            PPP LP G    S P  P G A   PP + G A  P    P P G G P P SL     I
Sbjct: 608  PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPP-PLPEGVGIPSPSSLPGGTAI 666

Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
                   G  +  P   P PG+     PPP   G +  P    P    PG  P    PG 
Sbjct: 667  PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG- 725

Query: 1105 ADPGTPLPPDPTAPSPGTVTPVPPP 1129
              PG P PP      PG   P PPP
Sbjct: 726  -GPGIPPPP------PGMGMPPPPP 743



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 62/238 (26%), Positives = 92/238 (38%), Gaps = 44/238 (18%)

Query: 910  VEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQ 969
            +++ K++   A   E + KKL+ +L    EL+  M +     E + Q L  ++ A H E+
Sbjct: 460  IDKTKVEKSEAKAAELE-KKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEK 518

Query: 970  LKYA-EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAG---PPAVHGLA-VAPASV 1024
             + A E +  +    Q+  +  +    L    + +    AA    PP+V   A V PA  
Sbjct: 519  QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPP 578

Query: 1025 VPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPG---AVPPGVPPPGPHGPSP 1081
            +P  +G+  PP                          P PG     PP  PPP P  P P
Sbjct: 579  LPGDSGTIIPP-------------------------PPAPGDSTTPPPPPPPPPPPPPLP 613

Query: 1082 FPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPT-----APSP-----GTVTPVPPP 1129
                 + P  +PG    S  P ++   T  PP P       PSP     GT  P PPP
Sbjct: 614  GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 671



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 2/37 (5%)

Query: 992  PPPALP--PGSQPIPPTGAAGPPAVHGLAVAPASVVP 1026
            PPP  P  PG  P PP     PP   G  V  A V+P
Sbjct: 719  PPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 755


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 71/265 (26%), Positives = 107/265 (40%), Gaps = 47/265 (17%)

Query: 903  KAKHLAAVEERKIKSLVALLVETQ--MKKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
            K++  AA  E+K+ S +    E Q  MKK+E     FE+    +  E++AL  ++QQ+  
Sbjct: 476  KSEAKAAELEKKLDSELTARHELQVEMKKME---SDFEQKLQDLQGEKDALHSEKQQIAT 532

Query: 961  DRQAFHMEQLKYA--------EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPT----GA 1008
            ++Q    E  +          E+   ++    +       PP++P  + P+PP     G 
Sbjct: 533  EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA-PVPPAPPLPGD 591

Query: 1009 AG----PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA------------- 1051
            +G    PP   G +  P    P P      PG +  S      G TA             
Sbjct: 592  SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 651

Query: 1052 --GPQQQQPAGAPQPGAVPPG--VPPPGP-HGPSPFPNQQTPPSMMPGA--VPGSGHPGV 1104
               P   +  G P P ++P G  +PPP P  G +  P    PP  +PG+  +P    P  
Sbjct: 652  PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP---PPPPPLPGSAGIPPPPPPLP 708

Query: 1105 ADPGTPLPPDPTAPSPGTVTPVPPP 1129
             + G P PP P    PG   P PPP
Sbjct: 709  GEAGMPPPPPPLPGGPG--IPPPPP 731



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 52/145 (35%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 992  PPPALPPG----SQPIPPTGAA--GPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQI 1044
            PPP LP G    S P  P G A   PP + G A  P    P P G G P P SL     I
Sbjct: 617  PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPP-PLPEGVGIPSPSSLPGGTAI 675

Query: 1045 GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGV 1104
                   G  +  P   P PG+     PPP   G +  P    P    PG  P    PG 
Sbjct: 676  PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG- 734

Query: 1105 ADPGTPLPPDPTAPSPGTVTPVPPP 1129
              PG P PP      PG   P PPP
Sbjct: 735  -GPGIPPPP------PGMGMPPPPP 752



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 62/238 (26%), Positives = 92/238 (38%), Gaps = 44/238 (18%)

Query: 910  VEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQ 969
            +++ K++   A   E + KKL+ +L    EL+  M +     E + Q L  ++ A H E+
Sbjct: 469  IDKTKVEKSEAKAAELE-KKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEK 527

Query: 970  LKYA-EMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAG---PPAVHGLA-VAPASV 1024
             + A E +  +    Q+  +  +    L    + +    AA    PP+V   A V PA  
Sbjct: 528  QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPP 587

Query: 1025 VPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPG---AVPPGVPPPGPHGPSP 1081
            +P  +G+  PP                          P PG     PP  PPP P  P P
Sbjct: 588  LPGDSGTIIPP-------------------------PPAPGDSTTPPPPPPPPPPPPPLP 622

Query: 1082 FPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPT-----APSP-----GTVTPVPPP 1129
                 + P  +PG    S  P ++   T  PP P       PSP     GT  P PPP
Sbjct: 623  GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 2/37 (5%)

Query: 992  PPPALP--PGSQPIPPTGAAGPPAVHGLAVAPASVVP 1026
            PPP  P  PG  P PP     PP   G  V  A V+P
Sbjct: 728  PPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
            sapiens]
          Length = 406

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 84/357 (23%), Positives = 125/357 (35%), Gaps = 33/357 (9%)

Query: 795  QATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEK 854
            +  DEK         GG  EE  + K     + +   G EG    + +  +G    +PE+
Sbjct: 25   EVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQ 84

Query: 855  EKE------PKEGQEE--VLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKH 906
            ++E      P++ QEE  +L+   E E   +T VE         TA          K + 
Sbjct: 85   QQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPER--KRRR 142

Query: 907  LAAVEERKIKSLVALLVETQM------KKLEIKLRHFEELETIMDREREALEYQRQQLLA 960
              A  + +++ L     E+Q       ++L  +L   E+   +  + R A   + Q++L 
Sbjct: 143  RTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLM 202

Query: 961  DRQAFHMEQLKYAEMRARQQHFQQ--------MHQQQQQP-PPALPPGSQPIPPTGAAGP 1011
             R     +     +M     ++          +H   Q P PP LP    P  P     P
Sbjct: 203  LRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMP 262

Query: 1012 PAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGV 1071
            P      + P  + P P GS   P   GP            P    P  AP P   P   
Sbjct: 263  PRPPIAPMPP--MAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAP 320

Query: 1072 PPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPP 1128
             PPGP      P  + PP      VP         PG P+ P P  P    + P PP
Sbjct: 321  VPPGP------PMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPP 371


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 53/166 (31%), Positives = 62/166 (37%), Gaps = 35/166 (21%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAV----APASVVPAP------------------ 1028
            Q PP+ PP S P+ P     P A + LAV    AP S  P+P                  
Sbjct: 631  QAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 689

Query: 1029 -AGSGAPPGSLGPSEQI---GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPN 1084
               S APP    P  Q+     A     P    P  AP P A PP   PP P    P   
Sbjct: 690  TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749

Query: 1085 QQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
              TPP  +P        P +A P   +PP P A  P +    PPPQ
Sbjct: 750  SATPPPRVP--------PLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 46/140 (32%), Positives = 57/140 (40%), Gaps = 14/140 (10%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            Q PP+ PP S P+ P+    P A   LA  P  V P+P  S  PP S           S 
Sbjct: 705  QVPPS-PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS--PPMS----------PSA 751

Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTP 1110
              P +  P  A  P  VPP  P   P  P   P  Q PP++    +     P  + PG  
Sbjct: 752  TPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG-Q 810

Query: 1111 LPPDPTAPSPGTVTPVPPPQ 1130
             P  P+A  P +    PPPQ
Sbjct: 811  APFSPSASLPMSPLATPPPQ 830



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 49/141 (34%), Positives = 57/141 (40%), Gaps = 19/141 (13%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            Q PP+ PP S P+ P+ A  PP V  L  AP   VP      +PP SL P   + +    
Sbjct: 736  QVPPS-PPASPPMSPS-ATPPPRVPPLLAAPPLQVPP-----SPPASL-PMSPLAKPPPQ 787

Query: 1051 AGPQQQQP--AGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPG 1108
            A P    P     P P A  PG  P  P    P     TPP   P        P +A P 
Sbjct: 788  APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--------PVLAAPL 839

Query: 1109 TPLPPDPTAPSPGTVTPVPPP 1129
              +PP P A SP    P  PP
Sbjct: 840  LQVPPSPPA-SPTLQAPRRPP 859



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 41/137 (29%), Positives = 53/137 (38%), Gaps = 8/137 (5%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            Q PP+ PP S P+ P     P A   LA  P   +P+P  S        PS  +  +   
Sbjct: 767  QVPPS-PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825

Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTP 1110
              P Q  P  A     VPP  PP  P   +P    + PP+  PG       P +     P
Sbjct: 826  TPPPQAPPVLAAPLLQVPPS-PPASPTLQAP----RRPPT--PGPDTSVSGPRLTLALAP 878

Query: 1111 LPPDPTAPSPGTVTPVP 1127
             PP P + SP +    P
Sbjct: 879  GPPPPPSRSPSSTLSGP 895



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 48/175 (27%), Positives = 58/175 (33%), Gaps = 43/175 (24%)

Query: 991  QPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1050
            + PP   P     PP+    PP        P+S+   P    APP    P  Q G     
Sbjct: 559  ETPPCPAPCPLQAPPSPLTTPPPE-----TPSSIATPPPQ--APPALASPPLQ-GLPSPP 610

Query: 1051 AGPQQQQPAGAPQPGAVPPGVPPP----------------------------GPHGPSPF 1082
              P    P  AP   A+PP   PP                             P  P P 
Sbjct: 611  LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670

Query: 1083 PNQQTP------PSMMPGAVPGS-GHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
            P  Q P      P + P A P S   P +A P   +PP P A  P + +  PPPQ
Sbjct: 671  PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 37/136 (27%), Positives = 46/136 (33%), Gaps = 1/136 (0%)

Query: 995  ALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQ 1054
            +L P S   PP     PP  +  ++AP  +  A A    P     P        +   P 
Sbjct: 517  SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL 576

Query: 1055 QQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPD 1114
               P   P   A PP   PP    P P     +PP       P    P +A P    PP 
Sbjct: 577  TTPPPETPSSIATPPPQAPPALASP-PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635

Query: 1115 PTAPSPGTVTPVPPPQ 1130
            P A  P +    P PQ
Sbjct: 636  PPASPPLSPLATPSPQ 651



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 41/133 (30%), Positives = 52/133 (39%), Gaps = 11/133 (8%)

Query: 1005 PTGAAGP--PAVHGL-AVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA 1061
            P   A P  P   GL A+ P  V P P    AP  +LGP      A  +    + +P   
Sbjct: 263  PRAPAHPSQPKPKGLQALRPPQVTP-PRKDAAP--ALGPLSSSPLATPSPSGTKARPVPP 319

Query: 1062 PQPGAVP-PGVPPPGPHGPSPFP----NQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPT 1116
            P   A P P   PP P   +P P    +   PPS+     P +  P  A P    PP   
Sbjct: 320  PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379

Query: 1117 APSPGTVTPVPPP 1129
             PS  T+ P+  P
Sbjct: 380  PPSLQTIPPIQVP 392



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/151 (28%), Positives = 55/151 (36%), Gaps = 17/151 (11%)

Query: 995  ALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPP----GSLGPSE-QIGQAGS 1049
            +L   S   P +    PP     ++AP S+   PA    PP     SL P   Q   A  
Sbjct: 494  SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553

Query: 1050 TAGPQQQQPAGAPQPGAVPPG---VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAD 1106
            T    +  P  AP P   PP     PPP        P  Q PP++    + G   P ++ 
Sbjct: 554  TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613

Query: 1107 PGTP---------LPPDPTAPSPGTVTPVPP 1128
              TP         LPP    PSP    P+ P
Sbjct: 614  LATPPPQAPPXLALPPLQAPPSPPASPPLSP 644



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 41/150 (27%), Positives = 59/150 (39%), Gaps = 21/150 (14%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGS-TAG 1052
            P  PP   P P T  +GP     LA+AP    P P  S +P  +L   +  G + S T+ 
Sbjct: 855  PRRPP--TPGPDTSVSGPRLT--LALAPG---PPPPPSRSPSSTLSGPDLAGHSSSATST 907

Query: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHG---PSPFPNQQTPPSMMPGAV------PGSGHPG 1103
            P++ +   +   G      PP        P+ +     PP    GA       P +  PG
Sbjct: 908  PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 967

Query: 1104 VADPGTPL----PPDPTAPSPGTVTPVPPP 1129
             AD    +     P+   P+PG + P P P
Sbjct: 968  SADGLCTIYETEGPESATPAPGALDPGPSP 997



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 35/121 (28%), Positives = 47/121 (38%), Gaps = 4/121 (3%)

Query: 1009 AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPS--EQIGQAGSTAGPQQQQPAGAPQPGA 1066
            AG  A    A AP  + P P GS  PP  + P+    +G AG+       + AG      
Sbjct: 10   AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 1067 VPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPV 1126
            +P   P  GP   S   + + P S  P +  G   P  A   +P P      + GT  P 
Sbjct: 70   IPESAPRAGP-TRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRASGTTRPG 127

Query: 1127 P 1127
            P
Sbjct: 128  P 128



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 37/123 (30%), Positives = 43/123 (34%), Gaps = 29/123 (23%)

Query: 1000 SQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPA 1059
            ++P+PP   A  P    L  +P    P P    APP    P            P  Q   
Sbjct: 314  ARPVPPPDNAATPLPATLPPSPPLATPLPL---APPSPSAP------------PSLQT-- 356

Query: 1060 GAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMM---PGAVPGSGHPGVADPGTPLPPDPT 1116
              P P A PP   PP        P  Q PPS+    P  VP S    +  P    PP P 
Sbjct: 357  -LPSPPATPPSQAPPS----MTTPPMQAPPSLQTIPPIQVPHS----LTSPSLQAPPSPL 407

Query: 1117 APS 1119
            A S
Sbjct: 408  ALS 410



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 33/107 (30%), Positives = 41/107 (38%), Gaps = 8/107 (7%)

Query: 997  PPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQ 1056
            PPGS   PP     P A+  L  A A V   P    A  G +G    I ++   AGP + 
Sbjct: 29   PPGSPRPPP--PVTPAALRVLGAAGA-VGRKPLAERA--GGIG-GATIPESAPRAGPTRS 82

Query: 1057 QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPG 1103
                +  P + PP     G   P P  N    P   PG   G+  PG
Sbjct: 83   AGTSSRNPASRPP-ASGRGERAP-PAKNTSPGPVSSPGRASGTTRPG 127


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 85/347 (24%), Positives = 131/347 (37%), Gaps = 55/347 (15%)

Query: 820  KTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTK 879
            K +  P K+E          ES  S+  P+  P +E  P    EE   E  E +   K +
Sbjct: 324  KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLK-Q 382

Query: 880  VERDIGEGNLSTAAAAALAAAAVKAKHLAAVEE-RKIKSLVALLVETQMKKLEIKLRHFE 938
            ++                    +  KH    +  ++ + ++      Q   ++++LRH+E
Sbjct: 383  LQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYE 442

Query: 939  ELETIMDREREALEYQRQQLLADRQAF---HMEQLKYAE---------MRARQQH----- 981
              +       +  E++R+  L + Q     H +QL+  E         M+A Q +     
Sbjct: 443  MQQQQFQHLYQ--EWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKV 500

Query: 982  --FQQMHQQ----QQQPPPALPPGSQPIP-PTGAAGPPAVHGLAVAPASVVPAPAGSGAP 1034
              FQ M  Q       PPP +P    P P PT    PP V   ++ P  + PA   +  P
Sbjct: 501  NSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTM---PPPVLPPSLPPPVMPPALPATVPP 557

Query: 1035 PG-----------SLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFP 1083
            PG           +  P   +  + S+AGP    P  +      PP +PPP     +P P
Sbjct: 558  PGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPP 617

Query: 1084 NQQTPPSMMPGAVPGSGHPGVADPGTP--LPPDPTAPSPGTVTPVPP 1128
                PP  +  A P    PG+  PG P  +PP  TA       PVPP
Sbjct: 618  VMPLPP--LSSATP---PPGIPPPGVPQGIPPQLTA------APVPP 653



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 52/167 (31%), Positives = 62/167 (37%), Gaps = 36/167 (21%)

Query: 977  ARQQHFQQMHQQQQQ---------PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPA 1027
            A+ Q  QQMHQ+Q Q         PPP  PP   P+ P G  G               P 
Sbjct: 59   AQLQQLQQMHQKQMQCVLQPHHLPPPPLPPP---PVMPGGGYG------------DWQPP 103

Query: 1028 PAGSGAPPG-SLGPSEQIGQAGSTAGPQQQQPAG-APQPGAVPPGVP--PPGPHGP---S 1080
            P     PPG +L   +Q          Q+  P G  P     PP  P  PPG + P   S
Sbjct: 104  PPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQS 163

Query: 1081 PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVP 1127
              P  Q PPS  P   P S  P +  P     P  + PS   + P P
Sbjct: 164  YMPPPQPPPSYYP---PTSSQPYL--PPAQPSPSQSPPSQSYLAPTP 205



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 48/157 (30%), Positives = 61/157 (38%), Gaps = 24/157 (15%)

Query: 978  RQQHFQQMHQQQQQPPPAL-------PPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAG 1030
            +QQ+  QM   Q+  PP L       PP S P+PP G+  PP+   +        P P  
Sbjct: 120  QQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPP-GSYMPPSQSYMP------PPQPPP 172

Query: 1031 SGAPPGSLGPSEQIGQ-AGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP 1089
            S  PP S  P     Q + S + P Q   A  P   +          H  S  P+ Q  P
Sbjct: 173  SYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP 232

Query: 1090 SMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPV 1126
            S      P  GH   +      PP P+AP PG  T V
Sbjct: 233  SR-----PSQGH---SKSQLLAPPPPSAP-PGNKTTV 260



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 46/155 (29%), Positives = 60/155 (38%), Gaps = 24/155 (15%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGL-----AVAPASVVPAPAGSGAPPG-SLGPSEQIG 1045
            PPP LPP     P   +  PP V  L     A  P  + P     G PP  +  P     
Sbjct: 601  PPPVLPP-----PSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPAS 655

Query: 1046 QAGSTAGPQQQQPAGAPQP---GAVPPGV--PPPGPHGPSPFPNQQTP--PSMMP----G 1094
             + S+  P++ +PA  P P   G+ PP    PP    GPS   N + P   S +P     
Sbjct: 656  SSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFS 715

Query: 1095 AVPGSGHPGVADPGTPLPPDPTAP-SPGTVTPVPP 1128
            +  G G    A P  P+      P   G + P PP
Sbjct: 716  SDQGLGESSAA-PSQPITAVKDMPVRSGGLLPDPP 749



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 46/165 (27%), Positives = 57/165 (34%), Gaps = 36/165 (21%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
            PPP +PP      P   A P A  G   + ++   AP+ SG          Q+ Q     
Sbjct: 15   PPPPVPP------PPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68

Query: 1052 GPQQQ---QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPG---------- 1098
              Q Q   QP   P P   PP V P G +G      Q  PP M P   P           
Sbjct: 69   QKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDW----QPPPPPMPPPPGPALSYQKQQQYK 124

Query: 1099 --------SGHPGVADPGTPLPPDPTAPSPGTVTP-----VPPPQ 1130
                     G PG+       PP+     PG+  P     +PPPQ
Sbjct: 125  HQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQ 169



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 26/68 (38%), Positives = 30/68 (44%), Gaps = 8/68 (11%)

Query: 1062 PQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPG 1121
            P P      +PPP P  P P      PP +MP A+P +    V  PG P P  P    P 
Sbjct: 517  PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPAT----VPPPGMPPPVMP----PS 568

Query: 1122 TVTPVPPP 1129
              T VPPP
Sbjct: 569  LPTSVPPP 576



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 9/63 (14%)

Query: 1069 PGV-PPPGPHGPSPFPNQQTPPSMM-PGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPV 1126
            PG+ PPPG + P P P  + P S++ P A P      V  P  P+PP P  P      P+
Sbjct: 1503 PGMYPPPGSYRPPP-PMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP------PL 1555

Query: 1127 PPP 1129
            PPP
Sbjct: 1556 PPP 1558



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 48/185 (25%), Positives = 71/185 (38%), Gaps = 24/185 (12%)

Query: 958  LLADRQAFHMEQLKYAE----MRARQQHFQQMHQQQQQPPPA--LPPGSQPIPPTGAAGP 1011
            +L+ RQ  H   LK A+    +R +++  Q+M     +P  A  LPP    +  T +   
Sbjct: 1447 VLSQRQ--HEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRP- 1503

Query: 1012 PAVHGLAVAPASVVPAPAGSGAPPGSL-GPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPG 1070
                G+   P S  P P   G PPGS+  PS        ++ P  + P   P P   PP 
Sbjct: 1504 ----GMYPPPGSYRPPPP-MGKPPGSIVRPS---APPARSSVPVTRPPVPIPPPPPPPPL 1555

Query: 1071 VPPPGPHGP--SPFPNQQTPPSMMPGAVPGSGHPGV----ADPGTPLPPDPTAPSPGTVT 1124
             PPP    P  S    ++       G    +   G+          +P  P  P P   +
Sbjct: 1556 PPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHS 1615

Query: 1125 PVPPP 1129
             +PPP
Sbjct: 1616 SIPPP 1620



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 44/201 (21%), Positives = 74/201 (36%), Gaps = 40/201 (19%)

Query: 931  EIKLRHFEELETIMDREREALEYQRQQLLADRQAFHM--EQLKYAEMRARQQHFQQMHQQ 988
            EI L+  +EL+ + + ++E L+  +      + A H+  ++ +     +R   +      
Sbjct: 1454 EIILKAAQELKMLRE-QKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSY 1512

Query: 989  QQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAG 1048
            +  PP   PPGS   P    + PPA   +   P +  P P     PP  L P   + +  
Sbjct: 1513 RPPPPMGKPPGSIVRP----SAPPARSSV---PVTRPPVPIPPPPPPPPLPPPPPVIKPQ 1565

Query: 1049 STAGPQQQ------------------------QPAGAPQPGAVPP-----GVPPPGPHGP 1079
            ++A  Q++                        + A  P    +PP      +PPPGP  P
Sbjct: 1566 TSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP-VP 1624

Query: 1080 SPFPNQQTPPSMMPGAVPGSG 1100
               P    PP +      G G
Sbjct: 1625 MGMPPMSKPPPVQQTVDYGHG 1645



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 47/198 (23%), Positives = 65/198 (32%), Gaps = 55/198 (27%)

Query: 984  QMHQQQQQPPPAL-PPGSQ-----PIPPTGAAGPPAVHGLAVAPA--------------- 1022
            Q +    QPPP+  PP S      P  P+ +  PP+   LA  P+               
Sbjct: 162  QSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS 221

Query: 1023 --------------------SVVPAPAGSGAPPGSLGPSEQ--IGQAGSTAGPQQQQPAG 1060
                                S + AP    APPG+    +Q  +         +QQQ A 
Sbjct: 222  QSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAP 281

Query: 1061 APQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVA-DPGTPLPPDPTAPS 1119
             P P  + P       +       QQ     +PG   G   P VA D   P+  + T P+
Sbjct: 282  EPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKG---PVVAKDTPEPVKEEVTVPA 338

Query: 1120 PGTV--------TPVPPP 1129
               V         P+PPP
Sbjct: 339  TSQVPESPSSEEPPLPPP 356


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 74/253 (29%), Positives = 95/253 (37%), Gaps = 47/253 (18%)

Query: 891  TAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLE-----IKLRHFEELETIMD 945
            TAAAA  AAAA  +      +E  + ++ +L        LE     ++ RH  E E    
Sbjct: 12   TAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPE---- 67

Query: 946  REREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPI-- 1003
            R R  LE   QQ    R ++     K +         Q   +    P P   P   P   
Sbjct: 68   RTRAELEKLIQQRAVLRVSY-----KGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAA 122

Query: 1004 -----PPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQP 1058
                 PPT A  PP     A APA    A A +   P S GP++         GP+ Q+ 
Sbjct: 123  AAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP--------GPRAQR- 173

Query: 1059 AGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP-GSGHPGVADPGTPLPPDPTA 1117
                   A P   PPP P           PP++ P A P  +  P VA    PLPP P  
Sbjct: 174  -------AAPLAAPPPAP---------AAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQP 217

Query: 1118 PSPGTVTPVPPPQ 1130
            P+P      PPPQ
Sbjct: 218  PAPPQQQQPPPPQ 230


>gi|4557317 annexin A11 [Homo sapiens]
          Length = 505

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 49/128 (38%), Positives = 55/128 (42%), Gaps = 14/128 (10%)

Query: 1007 GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG-PQQQQPAGAPQPG 1065
            GA  P    G   A    VP P G G PP +  P    G      G P  + P+  P PG
Sbjct: 67   GANMPNLYPGAPGAGYPPVP-PGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPG 125

Query: 1066 AVPPG--VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPG--TPLPPDPTAPSPG 1121
            A  PG  +PPPG   P  +P Q  PP   P      G P V  PG   P+P  P  P  G
Sbjct: 126  APVPGQPMPPPGQQPPGAYPGQ--PPVTYP------GQPPVPLPGQQQPVPSYPGYPGSG 177

Query: 1122 TVTPVPPP 1129
            TVTP  PP
Sbjct: 178  TVTPAVPP 185



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 50/137 (36%), Positives = 56/137 (40%), Gaps = 15/137 (10%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            P A   G  P+PP G   PP+     V P  + P P G+   P S  PS      G+   
Sbjct: 75   PGAPGAGYPPVPPGGFGQPPSAQQ-PVPPYGMYPPPGGN---PPSRMPSYP-PYPGAPVP 129

Query: 1053 PQQQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTP 1110
             Q   P G   PGA P  P V  PG   P P P QQ P    PG  PGSG        TP
Sbjct: 130  GQPMPPPGQQPPGAYPGQPPVTYPG-QPPVPLPGQQQPVPSYPG-YPGSG------TVTP 181

Query: 1111 LPPDPTAPSPGTVTPVP 1127
              P     S GT+T  P
Sbjct: 182  AVPPTQFGSRGTITDAP 198



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 45/142 (31%), Positives = 50/142 (35%), Gaps = 15/142 (10%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQIGQAGSTAG 1052
            P  PP     PP    G P        P S+ P    + A   G        G A + +G
Sbjct: 4    PGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSG 63

Query: 1053 PQQQQPAGAPQPGAVPPGVPP--PGPHGPSPFPNQQTPPSMM---PGAVPGSGHPGVADP 1107
                       PGA   G PP  PG  G  P   Q  PP  M   PG  P S  P     
Sbjct: 64   TFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY--- 120

Query: 1108 GTPLPPDPTAPSPGTVTPVPPP 1129
                PP P AP PG   P+PPP
Sbjct: 121  ----PPYPGAPVPG--QPMPPP 136



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 48/151 (31%), Positives = 56/151 (37%), Gaps = 24/151 (15%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAG--------------SGAPPGS 1037
            PP   PP +    P G A  P    +       V   AG              SG   G+
Sbjct: 9    PPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGA 68

Query: 1038 LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097
              P+   G  G  AG     P G  QP +    VPP G + P P  N   PPS MP   P
Sbjct: 69   NMPNLYPGAPG--AGYPPVPPGGFGQPPSAQQPVPPYGMY-PPPGGN---PPSRMPSYPP 122

Query: 1098 GSGHPGVADPGTPLPPDPTAPSPGTVTPVPP 1128
               +PG   PG P+PP P    PG     PP
Sbjct: 123  ---YPGAPVPGQPMPP-PGQQPPGAYPGQPP 149


>gi|22165433 annexin A11 [Homo sapiens]
          Length = 505

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 49/128 (38%), Positives = 55/128 (42%), Gaps = 14/128 (10%)

Query: 1007 GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG-PQQQQPAGAPQPG 1065
            GA  P    G   A    VP P G G PP +  P    G      G P  + P+  P PG
Sbjct: 67   GANMPNLYPGAPGAGYPPVP-PGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPG 125

Query: 1066 AVPPG--VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPG--TPLPPDPTAPSPG 1121
            A  PG  +PPPG   P  +P Q  PP   P      G P V  PG   P+P  P  P  G
Sbjct: 126  APVPGQPMPPPGQQPPGAYPGQ--PPVTYP------GQPPVPLPGQQQPVPSYPGYPGSG 177

Query: 1122 TVTPVPPP 1129
            TVTP  PP
Sbjct: 178  TVTPAVPP 185



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 50/137 (36%), Positives = 56/137 (40%), Gaps = 15/137 (10%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            P A   G  P+PP G   PP+     V P  + P P G+   P S  PS      G+   
Sbjct: 75   PGAPGAGYPPVPPGGFGQPPSAQQ-PVPPYGMYPPPGGN---PPSRMPSYP-PYPGAPVP 129

Query: 1053 PQQQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTP 1110
             Q   P G   PGA P  P V  PG   P P P QQ P    PG  PGSG        TP
Sbjct: 130  GQPMPPPGQQPPGAYPGQPPVTYPG-QPPVPLPGQQQPVPSYPG-YPGSG------TVTP 181

Query: 1111 LPPDPTAPSPGTVTPVP 1127
              P     S GT+T  P
Sbjct: 182  AVPPTQFGSRGTITDAP 198



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 45/142 (31%), Positives = 50/142 (35%), Gaps = 15/142 (10%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQIGQAGSTAG 1052
            P  PP     PP    G P        P S+ P    + A   G        G A + +G
Sbjct: 4    PGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSG 63

Query: 1053 PQQQQPAGAPQPGAVPPGVPP--PGPHGPSPFPNQQTPPSMM---PGAVPGSGHPGVADP 1107
                       PGA   G PP  PG  G  P   Q  PP  M   PG  P S  P     
Sbjct: 64   TFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY--- 120

Query: 1108 GTPLPPDPTAPSPGTVTPVPPP 1129
                PP P AP PG   P+PPP
Sbjct: 121  ----PPYPGAPVPG--QPMPPP 136



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 48/151 (31%), Positives = 56/151 (37%), Gaps = 24/151 (15%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAG--------------SGAPPGS 1037
            PP   PP +    P G A  P    +       V   AG              SG   G+
Sbjct: 9    PPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGA 68

Query: 1038 LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097
              P+   G  G  AG     P G  QP +    VPP G + P P  N   PPS MP   P
Sbjct: 69   NMPNLYPGAPG--AGYPPVPPGGFGQPPSAQQPVPPYGMY-PPPGGN---PPSRMPSYPP 122

Query: 1098 GSGHPGVADPGTPLPPDPTAPSPGTVTPVPP 1128
               +PG   PG P+PP P    PG     PP
Sbjct: 123  ---YPGAPVPGQPMPP-PGQQPPGAYPGQPP 149


>gi|22165431 annexin A11 [Homo sapiens]
          Length = 505

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 49/128 (38%), Positives = 55/128 (42%), Gaps = 14/128 (10%)

Query: 1007 GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG-PQQQQPAGAPQPG 1065
            GA  P    G   A    VP P G G PP +  P    G      G P  + P+  P PG
Sbjct: 67   GANMPNLYPGAPGAGYPPVP-PGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPG 125

Query: 1066 AVPPG--VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPG--TPLPPDPTAPSPG 1121
            A  PG  +PPPG   P  +P Q  PP   P      G P V  PG   P+P  P  P  G
Sbjct: 126  APVPGQPMPPPGQQPPGAYPGQ--PPVTYP------GQPPVPLPGQQQPVPSYPGYPGSG 177

Query: 1122 TVTPVPPP 1129
            TVTP  PP
Sbjct: 178  TVTPAVPP 185



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 50/137 (36%), Positives = 56/137 (40%), Gaps = 15/137 (10%)

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
            P A   G  P+PP G   PP+     V P  + P P G+   P S  PS      G+   
Sbjct: 75   PGAPGAGYPPVPPGGFGQPPSAQQ-PVPPYGMYPPPGGN---PPSRMPSYP-PYPGAPVP 129

Query: 1053 PQQQQPAGAPQPGAVP--PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTP 1110
             Q   P G   PGA P  P V  PG   P P P QQ P    PG  PGSG        TP
Sbjct: 130  GQPMPPPGQQPPGAYPGQPPVTYPG-QPPVPLPGQQQPVPSYPG-YPGSG------TVTP 181

Query: 1111 LPPDPTAPSPGTVTPVP 1127
              P     S GT+T  P
Sbjct: 182  AVPPTQFGSRGTITDAP 198



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 45/142 (31%), Positives = 50/142 (35%), Gaps = 15/142 (10%)

Query: 994  PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAP-PGSLGPSEQIGQAGSTAG 1052
            P  PP     PP    G P        P S+ P    + A   G        G A + +G
Sbjct: 4    PGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSG 63

Query: 1053 PQQQQPAGAPQPGAVPPGVPP--PGPHGPSPFPNQQTPPSMM---PGAVPGSGHPGVADP 1107
                       PGA   G PP  PG  G  P   Q  PP  M   PG  P S  P     
Sbjct: 64   TFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY--- 120

Query: 1108 GTPLPPDPTAPSPGTVTPVPPP 1129
                PP P AP PG   P+PPP
Sbjct: 121  ----PPYPGAPVPG--QPMPPP 136



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 48/151 (31%), Positives = 56/151 (37%), Gaps = 24/151 (15%)

Query: 992  PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAG--------------SGAPPGS 1037
            PP   PP +    P G A  P    +       V   AG              SG   G+
Sbjct: 9    PPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGA 68

Query: 1038 LGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097
              P+   G  G  AG     P G  QP +    VPP G + P P  N   PPS MP   P
Sbjct: 69   NMPNLYPGAPG--AGYPPVPPGGFGQPPSAQQPVPPYGMY-PPPGGN---PPSRMPSYPP 122

Query: 1098 GSGHPGVADPGTPLPPDPTAPSPGTVTPVPP 1128
               +PG   PG P+PP P    PG     PP
Sbjct: 123  ---YPGAPVPGQPMPP-PGQQPPGAYPGQPP 149


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
          Length = 2462

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 78/352 (22%), Positives = 141/352 (40%), Gaps = 41/352 (11%)

Query: 786  GNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSD 845
            G  + + + Q   ++++ ++P       E++ KEK  EA K++E+   E D E   ++  
Sbjct: 491  GKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKT 550

Query: 846  GDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAK 905
             D   +   EKE    +    ++   S+G RK ++ R     +++  A +  A    ++ 
Sbjct: 551  DDTSGEDNDEKEAVASKG---RKTANSQGRRKGRITR-----SMANEANSEEAITPQQSA 602

Query: 906  HLAAVEERKIKSLVALLVETQMKKLEIKLRHFEEL------ETIMDREREALEYQRQQLL 959
             LA++E  +        +ET  K L    R++  +      +T+   +     Y+++Q L
Sbjct: 603  ELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNL 662

Query: 960  AD-RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLA 1018
             +  Q   ++  K    R +++       ++   PP +    + +  +G +G      + 
Sbjct: 663  DEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVE--DEEMEASGVSGNEE-EMVE 719

Query: 1019 VAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHG 1078
             A A+V  +      P      ++  GQ     GP+     GA  P   PPG P P P  
Sbjct: 720  EAEATVNNSSDTESIPSPHTEAAKDTGQ----NGPKPPATLGADGP---PPGPPTPPPE- 771

Query: 1079 PSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSPGTVTPVPPPQ 1130
              P P + TP S   GA              P PP P  PSP    PV P +
Sbjct: 772  DIPAPTEPTPASEATGA--------------PTPP-PAPPSPSAPPPVVPKE 808



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 135/634 (21%), Positives = 208/634 (32%), Gaps = 94/634 (14%)

Query: 545  QPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL----------------QTSASQQ 588
            Q   P+  Q + D K   K  E ++  PE    K +L                +  AS+ 
Sbjct: 509  QQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKG 568

Query: 589  MLNFPDKGKEK---PTDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALE 645
                  +G+ K      M N     +  T +     +    + +  WTE+E     + L 
Sbjct: 569  RKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLL 628

Query: 646  MYKDDWNKVSEHVGSRTQDEC---ILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGN 702
             +  +W+ ++  VGS+T  +C     ++ +    D  L+  +  +           ++  
Sbjct: 629  EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA 688

Query: 703  PVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVP--TALVEAHVRKVEEAAKVTGKA 760
                  AF   V D  + ++      EE  +  E     ++  E+      EAAK TG+ 
Sbjct: 689  AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQN 748

Query: 761  DP----AFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEE 816
             P      G +     G  +  PE I                   EP    E  GA    
Sbjct: 749  GPKPPATLGADGPP-PGPPTPPPEDIPAP---------------TEPTPASEATGAPTPP 792

Query: 817  AKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGER 876
                +  AP     K      EKE E +   P+ + E++K P    EE+  +  ++E   
Sbjct: 793  PAPPSPSAPPPVVPK-----EEKEEETAAAPPVEEGEEQKPP--AAEELAVDTGKAEEPV 845

Query: 877  KTKVERDIGEG---NLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIK 933
            K++   +  EG        AA A A  A+KA+       R           T  K     
Sbjct: 846  KSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGR----------ATTAKSSGAP 895

Query: 934  LRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMH-QQQQQP 992
                       D   EA    + +LL+ R +         + RA     + +  +Q +Q 
Sbjct: 896  QDSDSSATCSADEVDEAEGGDKNRLLSPRPSL---LTPTGDPRANASPQKPLDLKQLKQR 952

Query: 993  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG 1052
              A+P    PI  T    PP        PA   P P  +  P             G +  
Sbjct: 953  AAAIP----PIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS 1008

Query: 1053 PQQQQPAGAPQPGAVP---------PGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPG 1103
            P       A +P   P         PG PP    G  PFP    PP  +  A P +  P 
Sbjct: 1009 PAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSG-LPFP---VPPREVIKASPHAPDPS 1064

Query: 1104 V---ADPGTPLP------PDPTAPSPGTVTPVPP 1128
                A PG PLP        P  P P T++  PP
Sbjct: 1065 AFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPP 1098



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/102 (25%), Positives = 37/102 (36%), Gaps = 3/102 (2%)

Query: 305 PSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTK 364
           PSP  EA K   + GP  P T    G          +D+  P+      E T   T    
Sbjct: 735 PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPA 794

Query: 365 KDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQ 406
             S SAP     +   +E+E+E+      +E E       E+
Sbjct: 795 PPSPSAP---PPVVPKEEKEEETAAAPPVEEGEEQKPPAAEE 833


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.129    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,264,523
Number of Sequences: 37866
Number of extensions: 3581698
Number of successful extensions: 65284
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 865
Number of HSP's successfully gapped in prelim test: 2589
Number of HSP's that attempted gapping in prelim test: 21014
Number of HSP's gapped (non-prelim): 23242
length of query: 1130
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1017
effective length of database: 13,968,660
effective search space: 14206127220
effective search space used: 14206127220
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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