Search of human proteins with 21071037

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21071037 BCL-6 interacting corepressor isoform a [Homo
sapiens]
         (1721 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]  3495   0.0  
gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]   3495   0.0  
gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]  3477   0.0  
gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]  3446   0.0  
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                   323   7e-88
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    97   1e-19
gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens]             87   1e-16
gi|239754054 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]        85   7e-16
gi|239748581 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]        85   7e-16
gi|239742600 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]        85   7e-16
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         75   5e-13
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         75   5e-13
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    71   8e-12
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...    70   2e-11
gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]        69   3e-11
gi|14150169 acyl-coenzyme A binding domain containing 6 [Homo sa...    69   5e-11
gi|188219549 ankyrin repeat domain 32 [Homo sapiens]                   68   9e-11
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         67   1e-10
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         67   2e-10
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         67   2e-10
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         67   2e-10
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         67   2e-10
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         67   2e-10
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         67   2e-10
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    67   2e-10
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]                        65   6e-10
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         65   6e-10
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         65   6e-10
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]                         65   6e-10
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]                         65   6e-10

>gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]
          Length = 1721

 Score = 3495 bits (9062), Expect = 0.0
 Identities = 1721/1721 (100%), Positives = 1721/1721 (100%)

Query: 1    MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
            MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST
Sbjct: 1    MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60

Query: 61   AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
            AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP
Sbjct: 61   AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120

Query: 121  EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
            EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN
Sbjct: 121  EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180

Query: 181  INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
            INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN
Sbjct: 181  INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240

Query: 241  GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
            GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD
Sbjct: 241  GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300

Query: 301  SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
            SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH
Sbjct: 301  SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360

Query: 361  YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
            YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD
Sbjct: 361  YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420

Query: 421  GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
            GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS
Sbjct: 421  GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480

Query: 481  EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
            EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR
Sbjct: 481  EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540

Query: 541  SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
            SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ
Sbjct: 541  SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600

Query: 601  PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
            PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY
Sbjct: 601  PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660

Query: 661  PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
            PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL
Sbjct: 661  PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720

Query: 721  GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
            GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP
Sbjct: 721  GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780

Query: 781  TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
            TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP
Sbjct: 781  TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840

Query: 841  SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
            SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF
Sbjct: 841  SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900

Query: 901  LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
            LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS
Sbjct: 901  LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960

Query: 961  KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
            KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM
Sbjct: 961  KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020

Query: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
            MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC
Sbjct: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080

Query: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
            EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG
Sbjct: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140

Query: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200
            DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR
Sbjct: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200

Query: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260
            KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK
Sbjct: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260

Query: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320
            SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS
Sbjct: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320

Query: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380
            EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ
Sbjct: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380

Query: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440
            EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG
Sbjct: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440

Query: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500
            YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL
Sbjct: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500

Query: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560
            HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA
Sbjct: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560

Query: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620
            SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV
Sbjct: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620

Query: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680
            SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE
Sbjct: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680

Query: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721
            AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW
Sbjct: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721


>gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]
          Length = 1721

 Score = 3495 bits (9062), Expect = 0.0
 Identities = 1721/1721 (100%), Positives = 1721/1721 (100%)

Query: 1    MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
            MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST
Sbjct: 1    MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60

Query: 61   AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
            AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP
Sbjct: 61   AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120

Query: 121  EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
            EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN
Sbjct: 121  EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180

Query: 181  INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
            INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN
Sbjct: 181  INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240

Query: 241  GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
            GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD
Sbjct: 241  GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300

Query: 301  SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
            SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH
Sbjct: 301  SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360

Query: 361  YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
            YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD
Sbjct: 361  YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420

Query: 421  GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
            GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS
Sbjct: 421  GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480

Query: 481  EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
            EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR
Sbjct: 481  EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540

Query: 541  SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
            SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ
Sbjct: 541  SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600

Query: 601  PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
            PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY
Sbjct: 601  PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660

Query: 661  PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
            PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL
Sbjct: 661  PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720

Query: 721  GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
            GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP
Sbjct: 721  GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780

Query: 781  TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
            TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP
Sbjct: 781  TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840

Query: 841  SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
            SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF
Sbjct: 841  SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900

Query: 901  LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
            LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS
Sbjct: 901  LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960

Query: 961  KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
            KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM
Sbjct: 961  KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020

Query: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
            MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC
Sbjct: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080

Query: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
            EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG
Sbjct: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140

Query: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200
            DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR
Sbjct: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200

Query: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260
            KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK
Sbjct: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260

Query: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320
            SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS
Sbjct: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320

Query: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380
            EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ
Sbjct: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380

Query: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440
            EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG
Sbjct: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440

Query: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500
            YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL
Sbjct: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500

Query: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560
            HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA
Sbjct: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560

Query: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620
            SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV
Sbjct: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620

Query: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680
            SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE
Sbjct: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680

Query: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721
            AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW
Sbjct: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721


>gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]
          Length = 1755

 Score = 3477 bits (9017), Expect = 0.0
 Identities = 1721/1755 (98%), Positives = 1721/1755 (98%), Gaps = 34/1755 (1%)

Query: 1    MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
            MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST
Sbjct: 1    MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60

Query: 61   AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
            AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP
Sbjct: 61   AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120

Query: 121  EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
            EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN
Sbjct: 121  EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180

Query: 181  INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
            INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN
Sbjct: 181  INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240

Query: 241  GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
            GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD
Sbjct: 241  GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300

Query: 301  SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
            SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH
Sbjct: 301  SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360

Query: 361  YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
            YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD
Sbjct: 361  YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420

Query: 421  GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
            GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS
Sbjct: 421  GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480

Query: 481  EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
            EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR
Sbjct: 481  EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540

Query: 541  SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
            SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ
Sbjct: 541  SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600

Query: 601  PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
            PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY
Sbjct: 601  PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660

Query: 661  PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
            PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL
Sbjct: 661  PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720

Query: 721  GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
            GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP
Sbjct: 721  GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780

Query: 781  TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
            TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP
Sbjct: 781  TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840

Query: 841  SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
            SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF
Sbjct: 841  SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900

Query: 901  LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
            LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS
Sbjct: 901  LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960

Query: 961  KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
            KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM
Sbjct: 961  KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020

Query: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
            MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC
Sbjct: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080

Query: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
            EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG
Sbjct: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140

Query: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSK--------------------------------- 1167
            DSSHTETTAEEVPEDPLLKAKRRRVSK                                 
Sbjct: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKDDWPEREMTNSSSNHLEDPHYSELTNLKVCIEL 1200

Query: 1168 -GLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRK 1226
             GLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRK
Sbjct: 1201 TGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRK 1260

Query: 1227 RAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAK 1286
            RAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAK
Sbjct: 1261 RAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAK 1320

Query: 1287 QQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLT 1346
            QQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLT
Sbjct: 1321 QQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLT 1380

Query: 1347 GEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSP 1406
            GEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSP
Sbjct: 1381 GEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSP 1440

Query: 1407 QETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA 1466
            QETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA
Sbjct: 1441 QETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA 1500

Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
            LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT
Sbjct: 1501 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1560

Query: 1527 YSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANP 1586
            YSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANP
Sbjct: 1561 YSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANP 1620

Query: 1587 PGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIF 1646
            PGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIF
Sbjct: 1621 PGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIF 1680

Query: 1647 RCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSS 1706
            RCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSS
Sbjct: 1681 RCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSS 1740

Query: 1707 VEWLHPSDLASDNYW 1721
            VEWLHPSDLASDNYW
Sbjct: 1741 VEWLHPSDLASDNYW 1755


>gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]
          Length = 1703

 Score = 3446 bits (8936), Expect = 0.0
 Identities = 1703/1721 (98%), Positives = 1703/1721 (98%), Gaps = 18/1721 (1%)

Query: 1    MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
            MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST
Sbjct: 1    MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60

Query: 61   AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
            AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP
Sbjct: 61   AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120

Query: 121  EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
            EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN
Sbjct: 121  EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180

Query: 181  INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
            INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN
Sbjct: 181  INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240

Query: 241  GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
            GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD
Sbjct: 241  GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300

Query: 301  SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
            SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH
Sbjct: 301  SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360

Query: 361  YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
            YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD
Sbjct: 361  YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420

Query: 421  GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
            GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS
Sbjct: 421  GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480

Query: 481  EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
            EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR
Sbjct: 481  EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540

Query: 541  SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
            SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ
Sbjct: 541  SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600

Query: 601  PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
            PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY
Sbjct: 601  PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660

Query: 661  PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
            PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL
Sbjct: 661  PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720

Query: 721  GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
            GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP
Sbjct: 721  GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780

Query: 781  TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
            TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP
Sbjct: 781  TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840

Query: 841  SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
            SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF
Sbjct: 841  SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900

Query: 901  LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
            LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS
Sbjct: 901  LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960

Query: 961  KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
            KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQ                  RAM
Sbjct: 961  KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQ------------------RAM 1002

Query: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
            MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC
Sbjct: 1003 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1062

Query: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
            EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG
Sbjct: 1063 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1122

Query: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200
            DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR
Sbjct: 1123 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1182

Query: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260
            KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK
Sbjct: 1183 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1242

Query: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320
            SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS
Sbjct: 1243 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1302

Query: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380
            EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ
Sbjct: 1303 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1362

Query: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440
            EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG
Sbjct: 1363 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1422

Query: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500
            YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL
Sbjct: 1423 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1482

Query: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560
            HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA
Sbjct: 1483 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1542

Query: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620
            SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV
Sbjct: 1543 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1602

Query: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680
            SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE
Sbjct: 1603 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1662

Query: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721
            AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW
Sbjct: 1663 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1703


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score =  323 bits (829), Expect = 7e-88
 Identities = 209/546 (38%), Positives = 298/546 (54%), Gaps = 46/546 (8%)

Query: 1196 GRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGN-RSWSEESLKPSDNEQGLPVFS 1254
            G + + +  + T+PE+   G      + G    +AK + R +    L      Q   + S
Sbjct: 1175 GVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICS 1234

Query: 1255 GSPPMKSLSSTSAGGKKQAQPSCAP--ASRPPAKQQKIKENQKTDVLCADEEED------ 1306
                M    + S  G ++  P+      +  PAK++K+++ Q+     +   +D      
Sbjct: 1235 SFAGM----ADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQ 1290

Query: 1307 --------------CQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVE 1352
                           +AA  +    +  E+   + L K K    Q+SR+    TGEY  E
Sbjct: 1291 GRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQ--TGEYLTE 1348

Query: 1353 NAD-----GKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQ 1407
              D     G+  ++  RK+   SS       +          Q +  S +  LP +    
Sbjct: 1349 QEDEQRRKGRADLKA-RKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEP 1407

Query: 1408 ETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCAL 1467
               ++   P   R+      A  T+ + A     ++VVLYCL+    DVNHRDNAGY AL
Sbjct: 1408 ACLENSEKPSGKRKCKTKHMA--TVSEEA-----KDVVLYCLQKDSEDVNHRDNAGYTAL 1460

Query: 1468 HEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATY 1527
            HEAC+RGW +I+  LLE+GA+VNCSAQDGTRP+HDAV ND+LE + LLLSYGADPTLATY
Sbjct: 1461 HEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATY 1520

Query: 1528 SGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPP 1587
            SG+T MK+  S+ M++FL+D+L+DLQGR + D   +WDFY SSV E  D    D+L NPP
Sbjct: 1521 SGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPP 1580

Query: 1588 GPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFR 1647
            G  DQ+ DD    D F FE S+ PLLPCYN+QVSV++GP NW L SDVLK+LK+SSRIF+
Sbjct: 1581 GSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQ 1640

Query: 1648 CNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFN----PESKELLDLVEFTNEIQTLL 1703
              FP+ EI T+ +AEFYRQV++S L + ++     +    P S E ++LV +  ++  LL
Sbjct: 1641 ARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLL 1700

Query: 1704 GSSVEW 1709
            GS VE+
Sbjct: 1701 GSEVEF 1706



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 149/707 (21%), Positives = 244/707 (34%), Gaps = 130/707 (18%)

Query: 1   MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
           M+S  PLY  VH+W +S+R+RMCG +E+R+  ++D +++                 D   
Sbjct: 1   MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTG---------------DCQH 45

Query: 61  AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSE-KGREAATSTLGGLGFSSERN 119
               +   + S  +  L              +  G GS  +G +   S    LG  SE  
Sbjct: 46  FGSQEFCVSSSFSKVEL--------------TAVGSGSNARGADPDGSATEKLGHKSED- 90

Query: 120 PEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPL 179
                KP+ P+     A +     GF     +P              GL  PASD     
Sbjct: 91  -----KPDDPQPKMDYAGNVAEAEGFLVPLSSPGD------------GLKLPASDSAEAS 133

Query: 180 NING-ASYLRLPWVNPYMEGATPAIYPFLDS------PNKYSLNMYKALLPQQS-----Y 227
           N     S+  L          +PA    LDS       N + L      +P +       
Sbjct: 134 NSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVT 193

Query: 228 SLAQPLYSPVCTNGERFLYLP--------PPHYVGPHIPSSLASPMRLST--PSASPAIP 277
           +   PL +P+C        +P         P  V   +P S   P++++T  P+ SP + 
Sbjct: 194 TNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLA 253

Query: 278 PLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSP 337
           P+   A         +S  NP+   A   +        P +  V    P    L +P S 
Sbjct: 254 PVPALAPAPPSVPTLISDSNPLSVSA--SVLVPVPASAPPSGPVPLSAPAPAPLSVPVSA 311

Query: 338 RPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAP 397
            P   +  P  P+A T          ++  P+          S   P    S+G  P  P
Sbjct: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP-PSTP 370

Query: 398 EGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKV--VDVDASKA 455
                  P P  A   A        +P  +   T     T  P+  S  +  V   A++A
Sbjct: 371 TLIPAFAPTPVPAPTPAPIFT---PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQA 427

Query: 456 DHMKKM-----APTVLVHSR-------AGSGLVLSGSEIP-----KETLSPP------GN 492
             M+K+       TVL  S+          G  LS + +P       TL+ P       +
Sbjct: 428 PAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQD 487

Query: 493 GC--AIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGT 550
            C   +  S  + + P ++ V  P  ++    K +SL+   L    P   +++ P   G 
Sbjct: 488 RCLPGVLASPELRSYPYAFSVARPLTSD---SKLVSLEVNRLPCTSPSGSTTTQPAPDGV 544

Query: 551 DAVITNVSGSVSSA---GRPASASPAPNANA----------------DGTKTSRSSVETT 591
              + + S   +SA     P    PAP+ ++                +GT  + S +++ 
Sbjct: 545 PGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSP 604

Query: 592 PSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSI 638
           P + + +  PP   ++     SSK  +   P P    N+   PP  +
Sbjct: 605 PQLEREMASPPEC-SEMPLDLSSKSNRQKLPLP----NQRKTPPMPV 646



 Score = 47.8 bits (112), Expect = 9e-05
 Identities = 126/565 (22%), Positives = 191/565 (33%), Gaps = 103/565 (18%)

Query: 196 MEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPL---YSP--VCTNGERFLYLPPP 250
           M  ATPA  P   +P   S ++ +   P       Q +   + P  V T  +  +Y+PPP
Sbjct: 397 MPAATPAAIP-TSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455

Query: 251 HYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNS 310
               P   ++L + + +S+    P +P   +  D+ LP  +  SP    +  +YP+  + 
Sbjct: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPS--YLQDRCLPGVL-ASP----ELRSYPYAFSV 508

Query: 311 KQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAAD------TYSEFHKHYARI 364
            +P    +K V        +L +   P  SP     TQPA D        +      A++
Sbjct: 509 ARPLTSDSKLV--------SLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV 560

Query: 365 STSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSP 424
             +P   L  P  + +   PA      K P   E       V     K+  Q  ++ +SP
Sbjct: 561 LPTPQPLLPAPSGSSAPPHPA------KMPSGTEQQTEGTSVTFSPLKSPPQLEREMASP 614

Query: 425 PLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSG--SEI 482
           P         + ++ PLDLSSK         +  K     VL      S  +LS   S  
Sbjct: 615 P---------ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRS 665

Query: 483 PKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNG-KSMSLKNKALDWAIPQQRS 541
            + T +  GN      +  + +  S +V+    P    NG  S  +KN            
Sbjct: 666 QRTTQAAGGN-----VTSCLGSTSSPFVI---FPEIVRNGDPSTWVKN------------ 705

Query: 542 SSCPRMGGTDAVITNVSGSVSSAGRPASASPAPN--ANADGTKTSRSSVETTPSVIQHVG 599
                   + A+I+ + G+      P  AS   N   N    +  R   +  P  I   G
Sbjct: 706 --------STALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQG 757

Query: 600 QPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLP 659
           +P  T A      S  GA+   P    +     + P        E     P   P +  P
Sbjct: 758 EPKGTGATCGKKGSQAGAE-GQPSTVKRYTPARIAPGLPGCQTKELSLWKPTG-PANIYP 815

Query: 660 YPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLP---------------- 703
             +  G   S   L      Y    LL  G    G L P  G P                
Sbjct: 816 RCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSL 875

Query: 704 ------YGLPTGRP----EFVTYQD 718
                 +GLP G+P     FV  QD
Sbjct: 876 SSSEAVHGLPEGQPRPGGSFVPEQD 900


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 84/278 (30%), Positives = 122/278 (43%), Gaps = 41/278 (14%)

Query: 1303 EEEDCQAASLLQKYTDNSEK--------PSGKRLCKTKHLIPQESRRGLPLTGEYYVENA 1354
            +EE   ++ +++K T   +K        P  +R    K +  + S+R LP T     E  
Sbjct: 12   QEELPLSSDMVEKQTGKKDKDKVSLTKTPKLERGDGGKEVRERASKRKLPFTAGANGEQK 71

Query: 1355 DG---KVTVRRFRKRPEP----------------SSDYDLSPAKQEPKPFDRLQQLLPAS 1395
            D    K    R R + EP                 + Y LS  +Q       L   + A 
Sbjct: 72   DSDTEKQGPERKRIKKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVA-----LLMQMTAE 126

Query: 1396 QSTQLPCSSSPQETTQSR------PMPPEARRLIVNKN--AGETLLQRAARLGYEEVVLY 1447
            +S   P  ++P+  +QS       P      +  VNK    GET L RAA  G    +  
Sbjct: 127  ESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKE 186

Query: 1448 CLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVEND 1507
             +     DVN +D AG+ ALHEAC RG+ ++ + LL  GA+VN    D   PLHDA  N 
Sbjct: 187  LISEG-ADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNG 245

Query: 1508 HLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
            H ++V+LLL YG +P  +   G T +K+ +S  M   L
Sbjct: 246  HYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLL 283


>gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens]
          Length = 777

 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 106/416 (25%), Positives = 160/416 (38%), Gaps = 47/416 (11%)

Query: 1135 KRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGK 1194
            K+  S      E  +   P D   +AK+     G   KK+  L  + ++W  +    DG+
Sbjct: 170  KKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKT-LAEINQKWNLEAEKEDGE 228

Query: 1195 ---PGRQSRKEVTQATQPEAI--PQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQG 1249
                    +K V+  +QP  I  PQ     +        E++   S +E SL  ++  + 
Sbjct: 229  FDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIE- 287

Query: 1250 LPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQA 1309
                  SP  KS +      K       +  S P     K   + +   L +   + C+ 
Sbjct: 288  ------SPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNR---LSSPISKRCRT 338

Query: 1310 ASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEP 1369
            + L           SG  +   K  +P E+   +PL       +   KV     RK    
Sbjct: 339  SIL---------STSGDFV---KQTVPSEN---IPLPECSSPPSCKRKVGGTSGRKNSNM 383

Query: 1370 SSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAG 1429
            S               D    L P +  + L  SS  +  +    M       +   + G
Sbjct: 384  S---------------DEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNMAVKRNHRG 428

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            ETLL  A+  G    V Y L+N   D N +D+AG+  LHEAC  G L +V  LL++ A V
Sbjct: 429  ETLLHIASIKGDIPSVEYLLQNG-SDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALV 487

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
            N +      PLHDA +N H++IV+LLLSYGA        G   +  T  E M+  L
Sbjct: 488  NTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLL 543


>gi|239754054 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
          Length = 1873

 Score = 84.7 bits (208), Expect = 7e-16
 Identities = 53/144 (36%), Positives = 76/144 (52%), Gaps = 2/144 (1%)

Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
            +A R+      GE+ L  A R G   +V   +E+   DVN  DNAG+  LHEA   G ++
Sbjct: 1144 KAGRINKRNARGESQLHLAVRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSID 1202

Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTH 1537
            I+  LL+ GA VNC   DG  PLHDAV N+HL+   +LL  GA+P       ++ +    
Sbjct: 1203 IIVELLKAGAKVNCENIDGILPLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEAD 1262

Query: 1538 SELMEKFLTDY-LNDLQGRNDDDA 1560
             E M++ L  Y   +   R++ DA
Sbjct: 1263 DEKMKELLRSYGAIETVNRDESDA 1286



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 1/121 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            GE L+ +AA     ++V +C++ K  +VN    AG+ ALHEA   G+      LL+ GAD
Sbjct: 489  GENLVYKAALHDDADLVHHCIK-KGGNVNQPSYAGWTALHEASVGGFYRTASELLKGGAD 547

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
            VN        PLHDAV N H ++  LLL  GADP      G+  +       M++ L  Y
Sbjct: 548  VNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDLCMKRLLERY 607

Query: 1549 L 1549
            +
Sbjct: 608  I 608


>gi|239748581 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
          Length = 1873

 Score = 84.7 bits (208), Expect = 7e-16
 Identities = 53/144 (36%), Positives = 76/144 (52%), Gaps = 2/144 (1%)

Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
            +A R+      GE+ L  A R G   +V   +E+   DVN  DNAG+  LHEA   G ++
Sbjct: 1144 KAGRINKRNARGESQLHLAVRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSID 1202

Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTH 1537
            I+  LL+ GA VNC   DG  PLHDAV N+HL+   +LL  GA+P       ++ +    
Sbjct: 1203 IIVELLKAGAKVNCENIDGILPLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEAD 1262

Query: 1538 SELMEKFLTDY-LNDLQGRNDDDA 1560
             E M++ L  Y   +   R++ DA
Sbjct: 1263 DEKMKELLRSYGAIETVNRDESDA 1286



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 1/121 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            GE L+ +AA     ++V +C++ K  +VN    AG+ ALHEA   G+      LL+ GAD
Sbjct: 489  GENLVYKAALHDDADLVHHCIK-KGGNVNQPSYAGWTALHEASVGGFYRTASELLKGGAD 547

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
            VN        PLHDAV N H ++  LLL  GADP      G+  +       M++ L  Y
Sbjct: 548  VNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDLCMKRLLERY 607

Query: 1549 L 1549
            +
Sbjct: 608  I 608


>gi|239742600 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
          Length = 1873

 Score = 84.7 bits (208), Expect = 7e-16
 Identities = 53/144 (36%), Positives = 76/144 (52%), Gaps = 2/144 (1%)

Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
            +A R+      GE+ L  A R G   +V   +E+   DVN  DNAG+  LHEA   G ++
Sbjct: 1144 KAGRINKRNARGESQLHLAVRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSID 1202

Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTH 1537
            I+  LL+ GA VNC   DG  PLHDAV N+HL+   +LL  GA+P       ++ +    
Sbjct: 1203 IIVELLKAGAKVNCENIDGILPLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEAD 1262

Query: 1538 SELMEKFLTDY-LNDLQGRNDDDA 1560
             E M++ L  Y   +   R++ DA
Sbjct: 1263 DEKMKELLRSYGAIETVNRDESDA 1286



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 1/121 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            GE L+ +AA     ++V +C++ K  +VN    AG+ ALHEA   G+      LL+ GAD
Sbjct: 489  GENLVYKAALHDDADLVHHCIK-KGGNVNQPSYAGWTALHEASVGGFYRTASELLKGGAD 547

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
            VN        PLHDAV N H ++  LLL  GADP      G+  +       M++ L  Y
Sbjct: 548  VNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDLCMKRLLERY 607

Query: 1549 L 1549
            +
Sbjct: 608  I 608


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 62/196 (31%), Positives = 94/196 (47%), Gaps = 15/196 (7%)

Query: 1373 YDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEA---RRLIVNKN-- 1427
            Y LS  KQ       L   + A  ++     + P +TT ++   P +   ++  VNK   
Sbjct: 106  YPLSERKQMA-----LLMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNE 160

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
             GET L  AA  G  + V   +     +VN +D AG+  LHEAC  G+ ++ + L+  GA
Sbjct: 161  RGETPLHMAAIRGDVKQVKELISLG-ANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGA 219

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTD 1547
            DVN    D   PLHD+  + H +IV+LLL +G +P  A   G   + +  +E +E  L  
Sbjct: 220  DVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 279

Query: 1548 YLNDLQGRNDDDASGT 1563
             +      +DDD S T
Sbjct: 280  EV----PLSDDDESYT 291



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 63/319 (19%), Positives = 112/319 (35%), Gaps = 23/319 (7%)

Query: 1027 EMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNES-ERCEYSVG 1085
            ++KE     P  KDSE      +  E   G    + K + +E+      ES E+ E    
Sbjct: 746  DLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVE-KEIDIEKQEKHIKESKEKPEKRSQ 804

Query: 1086 NKHRDPFEAPEDKDLPVEKYFVERQPVSEPPAD--QVASDMPHSPTLRVDRKRKVSGDSS 1143
             K +D  E  E K    EK         +   D  +    +     L      K   +  
Sbjct: 805  IKEKD-IEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGE 863

Query: 1144 HTETTAEEVPEDPLLKAKRR--RVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRK 1201
             ++ TA     D   K++ +  R      P+K+RHL   +E+   +           S+ 
Sbjct: 864  KSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKS 923

Query: 1202 EVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKS 1261
            E           +G N  +++   K+ +++   S +  + K    E+   +  G+     
Sbjct: 924  E-----------KGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHE 972

Query: 1262 LSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSE 1321
                S   K + +P   P  +   K+ K  +  K      D+ +D    + L K    ++
Sbjct: 973  -KPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKE----RDKHKDKIQINSLLKLKSEAD 1027

Query: 1322 KPSGKRLCKTKHLIPQESR 1340
            KP  K    +K   P+E R
Sbjct: 1028 KPKPKSSPASKDTRPKEKR 1046


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 62/196 (31%), Positives = 94/196 (47%), Gaps = 15/196 (7%)

Query: 1373 YDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEA---RRLIVNKN-- 1427
            Y LS  KQ       L   + A  ++     + P +TT ++   P +   ++  VNK   
Sbjct: 129  YPLSERKQMA-----LLMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNE 183

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
             GET L  AA  G  + V   +     +VN +D AG+  LHEAC  G+ ++ + L+  GA
Sbjct: 184  RGETPLHMAAIRGDVKQVKELISLG-ANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGA 242

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTD 1547
            DVN    D   PLHD+  + H +IV+LLL +G +P  A   G   + +  +E +E  L  
Sbjct: 243  DVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 302

Query: 1548 YLNDLQGRNDDDASGT 1563
             +      +DDD S T
Sbjct: 303  EV----PLSDDDESYT 314



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 63/319 (19%), Positives = 112/319 (35%), Gaps = 23/319 (7%)

Query: 1027 EMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNES-ERCEYSVG 1085
            ++KE     P  KDSE      +  E   G    + K + +E+      ES E+ E    
Sbjct: 769  DLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVE-KEIDIEKQEKHIKESKEKPEKRSQ 827

Query: 1086 NKHRDPFEAPEDKDLPVEKYFVERQPVSEPPAD--QVASDMPHSPTLRVDRKRKVSGDSS 1143
             K +D  E  E K    EK         +   D  +    +     L      K   +  
Sbjct: 828  IKEKD-IEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGE 886

Query: 1144 HTETTAEEVPEDPLLKAKRR--RVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRK 1201
             ++ TA     D   K++ +  R      P+K+RHL   +E+   +           S+ 
Sbjct: 887  KSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKS 946

Query: 1202 EVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKS 1261
            E           +G N  +++   K+ +++   S +  + K    E+   +  G+     
Sbjct: 947  E-----------KGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHE 995

Query: 1262 LSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSE 1321
                S   K + +P   P  +   K+ K  +  K      D+ +D    + L K    ++
Sbjct: 996  -KPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKE----RDKHKDKIQINSLLKLKSEAD 1050

Query: 1322 KPSGKRLCKTKHLIPQESR 1340
            KP  K    +K   P+E R
Sbjct: 1051 KPKPKSSPASKDTRPKEKR 1069


>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
            polymerase 2 [Homo sapiens]
          Length = 1166

 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 48/159 (30%), Positives = 72/159 (45%), Gaps = 2/159 (1%)

Query: 1393 PASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENK 1452
            PA++     C +   E  + R + PE            T L  AA  G ++VV Y L+N 
Sbjct: 23   PAARELFEACRNGDVERVK-RLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNG 81

Query: 1453 ICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIV 1512
              +V  RD+ G   LH AC+ G   +V  LL +GAD N        PLH+A     +++ 
Sbjct: 82   -ANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 140

Query: 1513 RLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLND 1551
             +LL +GA+PT+    GRT + +           +Y  D
Sbjct: 141  IVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKD 179



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA     EV  Y L++   DVN +D  G   LH A + G +++   L++Y A VN
Sbjct: 681  TPLHLAAGYNNLEVAEYLLQHG-ADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVN 739

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLT 1546
             + +    PLH+A +    ++  LLL++GADPTL    G+T + +  ++ +   LT
Sbjct: 740  ATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLT 795



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 38/101 (37%), Positives = 51/101 (50%), Gaps = 1/101 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA      VV Y L++   DV+ +D  G   LH AC+ G   +   L+++GA VN
Sbjct: 528  TPLHFAAGYNRVSVVEYLLQHG-ADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVN 586

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
             +      PLH+A      EI +LLL +GADPT     G T
Sbjct: 587  VADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNT 627



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 1/107 (0%)

Query: 1440 GYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTR 1498
            GY  V ++  L     DV+ +D      LH AC+ G   +   L+++GA VN        
Sbjct: 220  GYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFT 279

Query: 1499 PLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
            PLH+A   + +E+  LLLSYGADPTL     ++ + +  +  +++ L
Sbjct: 280  PLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERL 326



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 35/115 (30%), Positives = 54/115 (46%), Gaps = 2/115 (1%)

Query: 1430 ETLLQRAARLGYEEVVLYC--LENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
            ET L  AA   Y +    C  L  K  ++N +       LH A  +   ++V  ++++ A
Sbjct: 365  ETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEA 424

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELME 1542
             VN     G   LH A    HL+  RLLLSYG DP + +  G T ++M +  + +
Sbjct: 425  KVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQ 479



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 1/104 (0%)

Query: 1417 PEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWL 1476
            P A+ ++  +   + LL+ +AR G EE ++  L     + +  D      LH A     +
Sbjct: 166  PSAKAVLTGEYKKDELLE-SARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 224

Query: 1477 NIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGA 1520
             IV+ LL++GADV+   +    PLH+A    H E+  LL+ +GA
Sbjct: 225  KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGA 268



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 40/143 (27%), Positives = 55/143 (38%), Gaps = 55/143 (38%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD---- 1488
            L  A   G+ EVV   L +   D N RDN  Y  LHEA  +G +++   LL++GA+    
Sbjct: 95   LHNACSFGHAEVVNLLLRHG-ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR 153

Query: 1489 ------------------------------------------------VNCSAQDGTR-- 1498
                                                            VNC A DG +  
Sbjct: 154  NTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKST 213

Query: 1499 PLHDAVENDHLEIVRLLLSYGAD 1521
            PLH A   + ++IV+LLL +GAD
Sbjct: 214  PLHLAAGYNRVKIVQLLLQHGAD 236



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 2/83 (2%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
            L  A   G+ EV    +++    VN  D   +  LHEA A+G   I + LL++GAD    
Sbjct: 563  LHNACSYGHYEVAELLVKHGAV-VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK 621

Query: 1493 AQDGTRPLHDAVENDHLEIVRLL 1515
             +DG  PL D V++   +I  LL
Sbjct: 622  NRDGNTPL-DLVKDGDTDIQDLL 643


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
            sapiens]
          Length = 950

 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 49/131 (37%), Positives = 65/131 (49%), Gaps = 10/131 (7%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENK-----ICDVN----HRDNAGYCALHEACARG 1474
            +N  A + LL  A R G  E V   LE       I D+N     + N G+  LH AC  G
Sbjct: 1    MNTEAEQQLLHHA-RNGNAEEVRQLLETMARNEVIADINCKGRSKSNLGWTPLHLACYFG 59

Query: 1475 WLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMK 1534
               +V+ LL+ GA+VN     G  PLH A      E+V LLL Y AD T+   SG+T  +
Sbjct: 60   HRQVVQDLLKAGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTIVNGSGQTAKE 119

Query: 1535 MTHSELMEKFL 1545
            +TH+E +   L
Sbjct: 120  VTHAEEIRSML 130



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 42/151 (27%), Positives = 57/151 (37%), Gaps = 30/151 (19%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA-----------LHEACA 1472
            V  + G+T L RAA  G +E+V+  LE    D    + +G  A           + EA  
Sbjct: 76   VLNDMGDTPLHRAAFTGRKELVMLLLEYN-ADTTIVNGSGQTAKEVTHAEEIRSMLEAVE 134

Query: 1473 RGWLNIVRHLLEYGA------------------DVNCSAQDGTRPLHDAVENDHLEIVRL 1514
            R     +  LL   A                  DVNCS Q G  PLH A    H +    
Sbjct: 135  RTQQRKLEELLLAAAREGKTTELTALLNRPNPPDVNCSDQLGNTPLHCAAYRAHKQCALK 194

Query: 1515 LLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
            LL  GADP L   + +  + +     M+  L
Sbjct: 195  LLRSGADPNLKNKNDQKPLDLAQGAEMKHIL 225


>gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]
          Length = 1378

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 50/127 (39%), Positives = 65/127 (51%), Gaps = 9/127 (7%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
            GETLL RA   G    V   L  +   +N RD  G+  LHEAC  G L IVR LL++GA 
Sbjct: 529  GETLLHRACIEGQLRRV-QDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAA 587

Query: 1488 --DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
              D      +G  PLHDA+   H E+  LLL  GA  TL T  G     ++  E +++++
Sbjct: 588  VDDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKG-----LSPLETLQQWV 642

Query: 1546 TDYLNDL 1552
              Y  DL
Sbjct: 643  KLYRRDL 649



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 28/64 (43%), Positives = 35/64 (54%)

Query: 1457 NHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLL 1516
            N R++ G   LH AC  G L  V+ L+  G  +N     G  PLH+A    HLEIVR LL
Sbjct: 523  NRRNDMGETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLL 582

Query: 1517 SYGA 1520
             +GA
Sbjct: 583  DHGA 586


>gi|14150169 acyl-coenzyme A binding domain containing 6 [Homo
            sapiens]
          Length = 282

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 40/94 (42%), Positives = 48/94 (51%), Gaps = 11/94 (11%)

Query: 1447 YCLENKI-----------CDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQD 1495
            YC EN I            DVN +D  G   LH AC RG   +V  LL++ AD+NC   +
Sbjct: 165  YCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNE 224

Query: 1496 GTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
            G   LH A   + L+IV LLL  GADPTL    G
Sbjct: 225  GQTALHYASACEFLDIVELLLQSGADPTLRDQDG 258



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 1/76 (1%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
            V    G  LL  A   G++E+V   L+++  D+N +DN G  ALH A A  +L+IV  LL
Sbjct: 187  VKDEEGRALLHWACDRGHKELVTVLLQHR-ADINCQDNEGQTALHYASACEFLDIVELLL 245

Query: 1484 EYGADVNCSAQDGTRP 1499
            + GAD     QDG  P
Sbjct: 246  QSGADPTLRDQDGCLP 261



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 17/57 (29%), Positives = 28/57 (49%)

Query: 1477 NIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
            +I + +     DVN   ++G   LH A +  H E+V +LL + AD       G+T +
Sbjct: 173  HITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTAL 229


>gi|188219549 ankyrin repeat domain 32 [Homo sapiens]
          Length = 1058

 Score = 67.8 bits (164), Expect = 9e-11
 Identities = 39/92 (42%), Positives = 53/92 (57%), Gaps = 1/92 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            GET L RA      E ++  L     D+N +DNAG+  LHEAC  G    V+ +L+   +
Sbjct: 807  GETALHRACINNQVEKLILLLSLPGIDINVKDNAGWTPLHEACNYGNTVCVQEILQRCPE 866

Query: 1489 VNCSAQ-DGTRPLHDAVENDHLEIVRLLLSYG 1519
            V+   Q DG  PLHDA+ N H+EI +LLL +G
Sbjct: 867  VDLLTQVDGVTPLHDALSNGHVEIGKLLLQHG 898


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 47/137 (34%), Positives = 74/137 (54%), Gaps = 9/137 (6%)

Query: 1423 IVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
            I N+N G   L  A++ G+ EVV   L+ +  +V+     G  ALH A   G   +V+ L
Sbjct: 69   ICNQN-GLNALHLASKEGHVEVVSELLQRE-ANVDAATKKGNTALHIASLAGQAEVVKVL 126

Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT----IMKMTHS 1538
            +  GA+VN  +Q+G  PL+ A + +HLE+V+ LL  GA  +LAT  G T     ++  H 
Sbjct: 127  VTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHD 186

Query: 1539 ELMEKFLTDYLNDLQGR 1555
            +++   L    ND +G+
Sbjct: 187  QVVSLLLE---NDTKGK 200



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 37/113 (32%), Positives = 56/113 (49%), Gaps = 7/113 (6%)

Query: 1424 VNKNAGETLLQRAA---RLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVR 1480
            ++  +G T L  AA   R+   EV++    N+   V+ +   GY  LH  C  G + IV 
Sbjct: 692  LSNKSGLTPLHLAAQEDRVNVAEVLV----NQGAHVDAQTKMGYTPLHVGCHYGNIKIVN 747

Query: 1481 HLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
             LL++ A VN   ++G  PLH A +  H  I+ +LL   A P   T +G T +
Sbjct: 748  FLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTAL 800



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 1/105 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA  G+ +V    L+ K  + N +   G+  LH AC +  + ++  LL++GA + 
Sbjct: 369  TALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 427

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
               + G  P+H A    H+ IV  L+ +GA P      G T + M
Sbjct: 428  AVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHM 472



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 4/124 (3%)

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
            +G T +  AA +G+  +V   + +     N  +  G  ALH A   G   +VR+L++ GA
Sbjct: 432  SGLTPIHVAAFMGHVNIVSQLMHHG-ASPNTTNVRGETALHMAARSGQAEVVRYLVQDGA 490

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELME---KF 1544
             V   A+D   PLH +      +IV+ LL  GA P  AT SG T + ++  E  E    F
Sbjct: 491  QVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550

Query: 1545 LTDY 1548
            L D+
Sbjct: 551  LLDH 554



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 9/130 (6%)

Query: 1418 EARRLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHE 1469
            E   L++ K+A        G T L  AA    ++V L  L+          N GY  LH 
Sbjct: 579  EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN-GYTPLHI 637

Query: 1470 ACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
            A  +  ++I   LLEYGAD N   + G   +H A +  H+++V LLL   A+  L+  SG
Sbjct: 638  AAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSG 697

Query: 1530 RTIMKMTHSE 1539
             T + +   E
Sbjct: 698  LTPLHLAAQE 707



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 1/102 (0%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            +T L  +ARLG  ++V   L+      N    +GY  LH +   G  ++   LL++GA +
Sbjct: 500  QTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASL 558

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            + + + G  PLH A +   LE+  LLL   A P  A  SG T
Sbjct: 559  SITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLT 600



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 1/104 (0%)

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
            +G T L  +AR G+E+V  + L++    ++     G+  LH A   G L +   LL+  A
Sbjct: 531  SGYTPLHLSAREGHEDVAAFLLDHG-ASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSA 589

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
              + + + G  PLH A   D+ ++  LLL  GA P  A  +G T
Sbjct: 590  SPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYT 633



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 43/160 (26%), Positives = 78/160 (48%), Gaps = 10/160 (6%)

Query: 1392 LPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLEN 1451
            L  ++  ++     P++  + R    + ++    K+       RAAR G+ E  L  ++N
Sbjct: 8    LKKNRDLEINAEEEPEKKRKHRKRSRDRKK----KSDANASYLRAARAGHLEKALDYIKN 63

Query: 1452 KICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEI 1511
             + D+N  +  G  ALH A   G + +V  LL+  A+V+ + + G   LH A      E+
Sbjct: 64   GV-DINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEV 122

Query: 1512 VRLLLSYGADPTLATYSGRTIMKM----THSELMEKFLTD 1547
            V++L++ GA+    + +G T + M     H E++ KFL D
Sbjct: 123  VKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVV-KFLLD 161



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 1/112 (0%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
            V   +G T L  AA  G   V    L N+   V+         LH A  RG  N+V+ LL
Sbjct: 230  VESKSGFTPLHIAAHYGNINVATLLL-NRAAAVDFTARNDITPLHVASKRGNANMVKLLL 288

Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            + GA ++   +DG  PLH    + H ++V +LL   A     T +G + + M
Sbjct: 289  DRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHM 340



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 1/103 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA+    ++    LE    D N     G  ++H A   G +++V  LL   A+
Sbjct: 631  GYTPLHIAAKKNQMDIATTLLEYG-ADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 689

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            VN S + G  PLH A + D + +  +L++ GA     T  G T
Sbjct: 690  VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYT 732



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 1/103 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L   AR G+E+VV   L+ +   +  +   G   LH A     LN V+ LL++   
Sbjct: 301  GLTPLHCGARSGHEQVVEMLLD-RAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP 359

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            V+    D    LH A    H ++ ++LL   A+P     +G T
Sbjct: 360  VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFT 402



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 1436 AARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQD 1495
            AA+ G+ ++V   L  +  +VN  + +G   LH A     +N+   L+  GA V+   + 
Sbjct: 671  AAQEGHVDMVSLLL-GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKM 729

Query: 1496 GTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            G  PLH      +++IV  LL + A     T +G T
Sbjct: 730  GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYT 765



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKI-CDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            T L  A++ G   +V   L+     D   RD  G   LH     G   +V  LL+  A +
Sbjct: 270  TPLHVASKRGNANMVKLLLDRGAKIDAKTRD--GLTPLHCGARSGHEQVVEMLLDRAAPI 327

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSY 1518
                ++G  PLH A + DHL  V+LLL +
Sbjct: 328  LSKTKNGLSPLHMATQGDHLNCVQLLLQH 356



 Score = 37.0 bits (84), Expect = 0.17
 Identities = 40/169 (23%), Positives = 67/169 (39%), Gaps = 16/169 (9%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L      G  ++V + L++    VN +   GY  LH+A  +G  +I+  LL+  A 
Sbjct: 730  GYTPLHVGCHYGNIKIVNFLLQHS-AKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 788

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
             N    +G         N  L I R L       TL   +  T+   T +E  +  + + 
Sbjct: 789  PNELTVNG---------NTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPET 839

Query: 1549 LNDLQGRNDDDA--SGTWDFYGSSVCEPDDESGYDVLANPP----GPED 1591
            +N++   +DD+   +   +         D E G D +        GP+D
Sbjct: 840  MNEVLDMSDDEVRKANAPEMLSDGEYISDVEEGEDAMTGDTDKYLGPQD 888



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  A + G+++VV   LEN     + +      ALH A  +        LL+   +
Sbjct: 173  GFTPLAVALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKAAALLLQNDNN 227

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGA 1520
             +  ++ G  PLH A    ++ +  LLL+  A
Sbjct: 228  ADVESKSGFTPLHIAAHYGNINVATLLLNRAA 259



 Score = 31.2 bits (69), Expect = 9.1
 Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 10/122 (8%)

Query: 503  STAPSSWVVPGPSPNEENNGKSMSLKNKAL-DWAIPQQ--RSSSCPRMGGTDAVITNV-- 557
            S   S W V  PSP +   G S +   K++ D A P +  R+ S P          N+  
Sbjct: 1535 SPLKSIWSVSTPSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQV 1594

Query: 558  -SGSVSSAGRPASASPAPNANADGTKTSRSS-VETTPSVIQHVG---QPPATPAKHSSST 612
             SG+++ A     A+P     ++ T +SR+S V T  S+++       PPA+P  + +  
Sbjct: 1595 SSGTLARAPAVTEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMY 1654

Query: 613  SS 614
            SS
Sbjct: 1655 SS 1656


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G + L  AA+  + E +   L++K C     D++G  ALH A A+G L  V+ L E+ + 
Sbjct: 89   GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 147

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            +N    DG  PL  AV+N H EI   LL +GAD      SGRT + +
Sbjct: 148  INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 194



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 32/107 (29%), Positives = 45/107 (42%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            N  +  L +A   G  E V   L  K       D+ G  A H A A+G +  +R ++ +G
Sbjct: 20   NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 79

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
             DV      G   LH A +N H E +R LL           SG+T +
Sbjct: 80   VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 126



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G   L  A + G+ E+  + L++   DVN R+ +G  AL  AC  G  N V  L++ GAD
Sbjct: 155  GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 213

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
            +N     G   LH +  +++  I  LLLS
Sbjct: 214  LNLVDSLGYNALHYSKLSENAGIQSLLLS 242



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            ++G+T L  AA  G  + V    E+K   +N +D  G   L  A   G   I   LL++G
Sbjct: 120  SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 178

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
            ADVN   + G   L  A E      V  L+  GAD  L    G
Sbjct: 179  ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 221



 Score = 32.3 bits (72), Expect = 4.1
 Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 9/101 (8%)

Query: 1450 ENKICDVNHRDNAGYCALHEACARGWLNIVRHLL-EYGADVNCSAQDGTRPLHDAVENDH 1508
            E K  + N  D+     L +A   G    V  LL + GA       +G    H A    H
Sbjct: 13   EKKTNEWNKNDDR----LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGH 68

Query: 1509 LEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
            +E +R+++++G D T    +G + +    K +H E + K L
Sbjct: 69   VECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 109


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G + L  AA+  + E +   L++K C     D++G  ALH A A+G L  V+ L E+ + 
Sbjct: 78   GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 136

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            +N    DG  PL  AV+N H EI   LL +GAD      SGRT + +
Sbjct: 137  INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 183



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 32/107 (29%), Positives = 45/107 (42%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            N  +  L +A   G  E V   L  K       D+ G  A H A A+G +  +R ++ +G
Sbjct: 9    NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 68

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
             DV      G   LH A +N H E +R LL           SG+T +
Sbjct: 69   VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 115



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G   L  A + G+ E+  + L++   DVN R+ +G  AL  AC  G  N V  L++ GAD
Sbjct: 144  GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 202

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
            +N     G   LH +  +++  I  LLLS
Sbjct: 203  LNLVDSLGYNALHYSKLSENAGIQSLLLS 231



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            ++G+T L  AA  G  + V    E+K   +N +D  G   L  A   G   I   LL++G
Sbjct: 109  SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 167

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
            ADVN   + G   L  A E      V  L+  GAD  L    G
Sbjct: 168  ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 210



 Score = 32.3 bits (72), Expect = 4.1
 Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 9/102 (8%)

Query: 1449 LENKICDVNHRDNAGYCALHEACARGWLNIVRHLL-EYGADVNCSAQDGTRPLHDAVEND 1507
            +E K  + N  D+     L +A   G    V  LL + GA       +G    H A    
Sbjct: 1    MEAKTNEWNKNDDR----LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKG 56

Query: 1508 HLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
            H+E +R+++++G D T    +G + +    K +H E + K L
Sbjct: 57   HVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 98


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G + L  AA+  + E +   L++K C     D++G  ALH A A+G L  V+ L E+ + 
Sbjct: 86   GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 144

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            +N    DG  PL  AV+N H EI   LL +GAD      SGRT + +
Sbjct: 145  INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 191



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 32/107 (29%), Positives = 45/107 (42%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            N  +  L +A   G  E V   L  K       D+ G  A H A A+G +  +R ++ +G
Sbjct: 17   NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
             DV      G   LH A +N H E +R LL           SG+T +
Sbjct: 77   VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 123



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G   L  A + G+ E+  + L++   DVN R+ +G  AL  AC  G  N V  L++ GAD
Sbjct: 152  GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 210

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
            +N     G   LH +  +++  I  LLLS
Sbjct: 211  LNLVDSLGYNALHYSKLSENAGIQSLLLS 239



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            ++G+T L  AA  G  + V    E+K   +N +D  G   L  A   G   I   LL++G
Sbjct: 117  SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
            ADVN   + G   L  A E      V  L+  GAD  L    G
Sbjct: 176  ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 1486 GADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELM 1541
            GA       +G    H A    H+E +R+++++G D T    +G + +    K +H E +
Sbjct: 43   GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102

Query: 1542 EKFL 1545
             K L
Sbjct: 103  RKLL 106


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G + L  AA+  + E +   L++K C     D++G  ALH A A+G L  V+ L E+ + 
Sbjct: 86   GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 144

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            +N    DG  PL  AV+N H EI   LL +GAD      SGRT + +
Sbjct: 145  INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 191



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 32/107 (29%), Positives = 45/107 (42%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            N  +  L +A   G  E V   L  K       D+ G  A H A A+G +  +R ++ +G
Sbjct: 17   NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
             DV      G   LH A +N H E +R LL           SG+T +
Sbjct: 77   VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 123



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G   L  A + G+ E+  + L++   DVN R+ +G  AL  AC  G  N V  L++ GAD
Sbjct: 152  GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 210

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
            +N     G   LH +  +++  I  LLLS
Sbjct: 211  LNLVDSLGYNALHYSKLSENAGIQSLLLS 239



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            ++G+T L  AA  G  + V    E+K   +N +D  G   L  A   G   I   LL++G
Sbjct: 117  SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
            ADVN   + G   L  A E      V  L+  GAD  L    G
Sbjct: 176  ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 1486 GADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELM 1541
            GA       +G    H A    H+E +R+++++G D T    +G + +    K +H E +
Sbjct: 43   GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102

Query: 1542 EKFL 1545
             K L
Sbjct: 103  RKLL 106


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G + L  AA+  + E +   L++K C     D++G  ALH A A+G L  V+ L E+ + 
Sbjct: 86   GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 144

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            +N    DG  PL  AV+N H EI   LL +GAD      SGRT + +
Sbjct: 145  INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 191



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 32/107 (29%), Positives = 45/107 (42%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            N  +  L +A   G  E V   L  K       D+ G  A H A A+G +  +R ++ +G
Sbjct: 17   NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
             DV      G   LH A +N H E +R LL           SG+T +
Sbjct: 77   VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 123



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G   L  A + G+ E+  + L++   DVN R+ +G  AL  AC  G  N V  L++ GAD
Sbjct: 152  GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 210

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
            +N     G   LH +  +++  I  LLLS
Sbjct: 211  LNLVDSLGYNALHYSKLSENAGIQSLLLS 239



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            ++G+T L  AA  G  + V    E+K   +N +D  G   L  A   G   I   LL++G
Sbjct: 117  SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
            ADVN   + G   L  A E      V  L+  GAD  L    G
Sbjct: 176  ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 1486 GADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELM 1541
            GA       +G    H A    H+E +R+++++G D T    +G + +    K +H E +
Sbjct: 43   GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102

Query: 1542 EKFL 1545
             K L
Sbjct: 103  RKLL 106


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G + L  AA+  + E +   L++K C     D++G  ALH A A+G L  V+ L E+ + 
Sbjct: 86   GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 144

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            +N    DG  PL  AV+N H EI   LL +GAD      SGRT + +
Sbjct: 145  INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 191



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 32/107 (29%), Positives = 45/107 (42%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            N  +  L +A   G  E V   L  K       D+ G  A H A A+G +  +R ++ +G
Sbjct: 17   NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
             DV      G   LH A +N H E +R LL           SG+T +
Sbjct: 77   VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 123



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G   L  A + G+ E+  + L++   DVN R+ +G  AL  AC  G  N V  L++ GAD
Sbjct: 152  GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 210

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
            +N     G   LH +  +++  I  LLLS
Sbjct: 211  LNLVDSLGYNALHYSKLSENAGIQSLLLS 239



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
            ++G+T L  AA  G  + V    E+K   +N +D  G   L  A   G   I   LL++G
Sbjct: 117  SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175

Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
            ADVN   + G   L  A E      V  L+  GAD  L    G
Sbjct: 176  ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 1486 GADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELM 1541
            GA       +G    H A    H+E +R+++++G D T    +G + +    K +H E +
Sbjct: 43   GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102

Query: 1542 EKFL 1545
             K L
Sbjct: 103  RKLL 106


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
            polymerase [Homo sapiens]
          Length = 1327

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 38/108 (35%), Positives = 57/108 (52%), Gaps = 1/108 (0%)

Query: 1440 GYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTR 1498
            GY  V ++  L     DV+ +D  G   LH AC+ G   +   LL++GA VN        
Sbjct: 378  GYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFT 437

Query: 1499 PLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLT 1546
            PLH+A   + +E+  LLLS+GADPTL    G++ + M  +  + + LT
Sbjct: 438  PLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLT 485



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 1/117 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA     EV  Y LE+   DVN +D  G   LH A + G ++I   L++Y   VN
Sbjct: 839  TPLHLAAGYNNLEVAEYLLEHG-ADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVN 897

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTD 1547
             + +    PLH+A +    ++  LLL++GADPT+    G+T + +  ++ +   L D
Sbjct: 898  ATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLID 954



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 6/124 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA      VV Y L +   DV+ +D  G   LH AC+ G   +   L+ +GA VN
Sbjct: 686  TPLHFAAGYNRVSVVEYLLHHG-ADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
             +      PLH+A      EI +LLL +GADPT     G T +     +L+++  TD  +
Sbjct: 745  VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL-----DLVKEGDTDIQD 799

Query: 1551 DLQG 1554
             L+G
Sbjct: 800  LLRG 803



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 1/119 (0%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
            L  AA  G ++VV + L+    +V+ RD+ G   LH AC+ G   +V  LL  GAD N  
Sbjct: 220  LHFAAGFGRKDVVEHLLQMG-ANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNAR 278

Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLND 1551
                  PLH+A     +++  +LL +GADP +    G++ + +           +Y  D
Sbjct: 279  DNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKD 337



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 35/104 (33%), Positives = 54/104 (51%), Gaps = 1/104 (0%)

Query: 1417 PEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWL 1476
            P A+ ++  +   + LL+ AAR G EE ++  L     + +  D      LH A     +
Sbjct: 324  PSAKAVLTGEYKKDELLE-AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 382

Query: 1477 NIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGA 1520
             IV+ LL++GADV+   + G  PLH+A    H E+  LLL +GA
Sbjct: 383  RIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA 426



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 1/99 (1%)

Query: 1449 LENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDH 1508
            L  K  +VN ++      LH A  R   +++  L ++GA +N     G   LH A    H
Sbjct: 544  LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH 603

Query: 1509 LEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTD 1547
            L+  RLLLSYG+DP++ +  G T  +M  +E +++ L++
Sbjct: 604  LQTCRLLLSYGSDPSIISLQGFTAAQM-GNEAVQQILSE 641



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA--LHEACARGWLNIVRHLLEYGADVN 1490
            L  A++ G  E V     ++  +VN RD  G  +  LH A     +++V +LL +GADV+
Sbjct: 654  LLEASKAGDLETVKQLCSSQ--NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVH 711

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLA 1525
               + G  PLH+A    H E+  LL+ +GA   +A
Sbjct: 712  AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVA 746



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 41/143 (28%), Positives = 53/143 (37%), Gaps = 55/143 (38%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD---- 1488
            L  A   G+ EVV   L     D N RDN  Y  LHEA  +G +++   LL++GAD    
Sbjct: 253  LHNACSFGHAEVVSLLLCQG-ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 311

Query: 1489 ------------------------------------------------VNCSAQDGTR-- 1498
                                                            VNC A DG +  
Sbjct: 312  NTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKST 371

Query: 1499 PLHDAVENDHLEIVRLLLSYGAD 1521
            PLH A   + + IV+LLL +GAD
Sbjct: 372  PLHLAAGYNRVRIVQLLLQHGAD 394



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 31/112 (27%), Positives = 42/112 (37%), Gaps = 14/112 (12%)

Query: 1393 PASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGE--------TLLQRAARLGYEEV 1444
            P S  T L C+          P   +   L++ K A          T L  AA   + +V
Sbjct: 519  PQSHETALHCA-----VASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDV 573

Query: 1445 VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDG 1496
             +  L      +N  D  G  ALH A   G L   R LL YG+D +  +  G
Sbjct: 574  -MEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQG 624



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 40/121 (33%), Positives = 45/121 (37%), Gaps = 19/121 (15%)

Query: 559 GSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQPPATPAKHSSSTSSKGAK 618
           GS     RP S  P      DGT     S  +T S I  V   P  PA    STSS    
Sbjct: 70  GSRDPPDRPRSPDPV-----DGT-----SCCSTTSTICTVAAAPVVPAV---STSSAAGV 116

Query: 619 ASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPYPAPEGI-AVSPLSLHGKG 677
           A NP  S     N  P SS   SP  +  S P     S    P   G+ + +PL     G
Sbjct: 117 APNPAGS---GSNNSPSSS--SSPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAG 171

Query: 678 P 678
           P
Sbjct: 172 P 172


>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
          Length = 1897

 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
            L  A++ G+ ++V+  L  +I  +      G  ALH A   G   +VR L+ YGA+VN  
Sbjct: 82   LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 140

Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
            +Q G  PL+ A + +HLE+V+ LL  GA+  +AT  G T + +   +  E  +   +N
Sbjct: 141  SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 198



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
            AG T L  AAR G+ E VL  LE +          G+  LH A   G + +   LLE  A
Sbjct: 535  AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 593

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
              N + ++G  PLH AV +++L+IV+LLL  G  P    ++G T
Sbjct: 594  HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 637



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
            +   +G T L   A+ G+  V    +++ +  V+     GY  LH A   G + +V+ LL
Sbjct: 696  LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 754

Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            ++ ADVN   + G  PLH A +  H +IV LLL  GA P   +  G T
Sbjct: 755  QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 802



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            ET L  AAR G+ EV  Y L+NK   VN +       LH A   G  N+V+ LLE  A+ 
Sbjct: 471  ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 529

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            N +   G  PLH A    H+E V  LL   A     T  G T
Sbjct: 530  NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 571



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA  G +EVV   L N   +VN +   G+  L+ A     L +V+ LLE GA+
Sbjct: 111  GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 169

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
             N + +DG  PL  A++  H  +V  L++YG
Sbjct: 170  QNVATEDGFTPLAVALQQGHENVVAHLINYG 200



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 29/77 (37%), Positives = 39/77 (50%)

Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
            GY  LH A  +  + + R LL+YG   N  +  G  PLH A +  H E+V LLLS  A+ 
Sbjct: 635  GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 694

Query: 1523 TLATYSGRTIMKMTHSE 1539
             L   SG T + +   E
Sbjct: 695  NLGNKSGLTPLHLVAQE 711



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA  G+  V    L+ K    N R   G+  LH AC +  + ++  LL+ GA ++
Sbjct: 373  TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 431

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
               + G  PLH A    HL IV+ LL  GA P ++     T + M     H+E + K+L 
Sbjct: 432  AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 490

Query: 1547 DYLNDLQGRNDDD 1559
                 +  +  DD
Sbjct: 491  QNKAKVNAKAKDD 503



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            +T L  AAR+G+  +V   LEN   + N    AG+  LH A   G +  V  LLE  A  
Sbjct: 504  QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 562

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
             C  + G  PLH A +   + +  LLL   A P  A  +G T + +   H+ L      D
Sbjct: 563  ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 616

Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
             +  L  R     S  W+ Y
Sbjct: 617  IVKLLLPRGGSPHSPAWNGY 636



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)

Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
            V    G T L  AA   YE + V   L N+   VN     G   LH A  RG + +VR L
Sbjct: 234  VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 291

Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            L+ GA +    +D   PLH A  N H+ I  +LL +GA     T +G + + M
Sbjct: 292  LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 344



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 28/73 (38%), Positives = 39/73 (53%)

Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
            LH A   G   + ++LL+  A VN  A+D   PLH A    H  +V+LLL   A+P LAT
Sbjct: 474  LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 533

Query: 1527 YSGRTIMKMTHSE 1539
             +G T + +   E
Sbjct: 534  TAGHTPLHIAARE 546



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)

Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
            +L++N+ A        G T L  A+R G   +++  L ++   +  +       LH A  
Sbjct: 256  QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 314

Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
             G + I   LL++GA +    ++G  P+H A + DHL+ VRLLL Y A+
Sbjct: 315  NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 363



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)

Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
            EA +  + K  G T L  AA+ G   V    LE      N     G   LH A     L+
Sbjct: 559  EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 616

Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
            IV+ LL  G   +  A +G  PLH A + + +E+ R LL YG      +  G T + +  
Sbjct: 617  IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 676

Query: 1537 ---HSELMEKFLTDYLN 1550
               H+E++   L+   N
Sbjct: 677  QEGHAEMVALLLSKQAN 693



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  A+  G  ++V + L+++  DVN +   GY  LH+A  +G  +IV  LL+ GA 
Sbjct: 734  GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 792

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
             N  + DGT PL  A    ++ +  +L
Sbjct: 793  PNEVSSDGTTPLAIAKRLGYISVTDVL 819



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AAR G+  +    L++    +  +   G   +H A     L+ VR LL+Y A+++
Sbjct: 307  TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 365

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
                D   PLH A    H  + ++LL  GA P     +G T +    K  H  +ME  L
Sbjct: 366  DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 424



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA+ G+ E+V   L +K  + N  + +G   LH     G + +   L+++G  
Sbjct: 668  GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 726

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
            V+ + + G  PLH A    ++++V+ LL + AD    T  G + +     +     +T  
Sbjct: 727  VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 786

Query: 1549 LNDLQGRNDDDASGT 1563
            L +    N+  + GT
Sbjct: 787  LKNGASPNEVSSDGT 801



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T   RAAR G  +  L  L N + D+N  +  G   LH A   G + +V  LL     + 
Sbjct: 47   TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 105

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
             + + G   LH A      E+VR L++YGA+    +  G T + M   E
Sbjct: 106  TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 154



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
            G T L  AA+  + EVV + LEN   + N     G+  L  A  +G  N+V HL+ YG  
Sbjct: 144  GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 202

Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
                           D   +A             + G  PLH A   ++L + +LLL+ G
Sbjct: 203  GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 262

Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
            A       +G T   I     + +M + L D    ++ +  D+
Sbjct: 263  ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 305


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
            L  A++ G+ ++V+  L  +I  +      G  ALH A   G   +VR L+ YGA+VN  
Sbjct: 49   LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 107

Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
            +Q G  PL+ A + +HLE+V+ LL  GA+  +AT  G T + +   +  E  +   +N
Sbjct: 108  SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
            AG T L  AAR G+ E VL  LE +          G+  LH A   G + +   LLE  A
Sbjct: 502  AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 560

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
              N + ++G  PLH AV +++L+IV+LLL  G  P    ++G T
Sbjct: 561  HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 604



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
            +   +G T L   A+ G+  V    +++ +  V+     GY  LH A   G + +V+ LL
Sbjct: 663  LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 721

Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            ++ ADVN   + G  PLH A +  H +IV LLL  GA P   +  G T
Sbjct: 722  QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            ET L  AAR G+ EV  Y L+NK   VN +       LH A   G  N+V+ LLE  A+ 
Sbjct: 438  ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            N +   G  PLH A    H+E V  LL   A     T  G T
Sbjct: 497  NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA  G +EVV   L N   +VN +   G+  L+ A     L +V+ LLE GA+
Sbjct: 78   GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
             N + +DG  PL  A++  H  +V  L++YG
Sbjct: 137  QNVATEDGFTPLAVALQQGHENVVAHLINYG 167



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 29/77 (37%), Positives = 39/77 (50%)

Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
            GY  LH A  +  + + R LL+YG   N  +  G  PLH A +  H E+V LLLS  A+ 
Sbjct: 602  GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661

Query: 1523 TLATYSGRTIMKMTHSE 1539
             L   SG T + +   E
Sbjct: 662  NLGNKSGLTPLHLVAQE 678



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA  G+  V    L+ K    N R   G+  LH AC +  + ++  LL+ GA ++
Sbjct: 340  TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
               + G  PLH A    HL IV+ LL  GA P ++     T + M     H+E + K+L 
Sbjct: 399  AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 457

Query: 1547 DYLNDLQGRNDDD 1559
                 +  +  DD
Sbjct: 458  QNKAKVNAKAKDD 470



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            +T L  AAR+G+  +V   LEN   + N    AG+  LH A   G +  V  LLE  A  
Sbjct: 471  QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 529

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
             C  + G  PLH A +   + +  LLL   A P  A  +G T + +   H+ L      D
Sbjct: 530  ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 583

Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
             +  L  R     S  W+ Y
Sbjct: 584  IVKLLLPRGGSPHSPAWNGY 603



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)

Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
            V    G T L  AA   YE + V   L N+   VN     G   LH A  RG + +VR L
Sbjct: 201  VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258

Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            L+ GA +    +D   PLH A  N H+ I  +LL +GA     T +G + + M
Sbjct: 259  LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 28/73 (38%), Positives = 39/73 (53%)

Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
            LH A   G   + ++LL+  A VN  A+D   PLH A    H  +V+LLL   A+P LAT
Sbjct: 441  LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500

Query: 1527 YSGRTIMKMTHSE 1539
             +G T + +   E
Sbjct: 501  TAGHTPLHIAARE 513



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)

Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
            +L++N+ A        G T L  A+R G   +++  L ++   +  +       LH A  
Sbjct: 223  QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 281

Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
             G + I   LL++GA +    ++G  P+H A + DHL+ VRLLL Y A+
Sbjct: 282  NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)

Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
            EA +  + K  G T L  AA+ G   V    LE      N     G   LH A     L+
Sbjct: 526  EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 583

Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
            IV+ LL  G   +  A +G  PLH A + + +E+ R LL YG      +  G T + +  
Sbjct: 584  IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 643

Query: 1537 ---HSELMEKFLTDYLN 1550
               H+E++   L+   N
Sbjct: 644  QEGHAEMVALLLSKQAN 660



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  A+  G  ++V + L+++  DVN +   GY  LH+A  +G  +IV  LL+ GA 
Sbjct: 701  GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
             N  + DGT PL  A    ++ +  +L
Sbjct: 760  PNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AAR G+  +    L++    +  +   G   +H A     L+ VR LL+Y A+++
Sbjct: 274  TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
                D   PLH A    H  + ++LL  GA P     +G T +    K  H  +ME  L
Sbjct: 333  DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA+ G+ E+V   L +K  + N  + +G   LH     G + +   L+++G  
Sbjct: 635  GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
            V+ + + G  PLH A    ++++V+ LL + AD    T  G + +     +     +T  
Sbjct: 694  VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753

Query: 1549 LNDLQGRNDDDASGT 1563
            L +    N+  + GT
Sbjct: 754  LKNGASPNEVSSDGT 768



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T   RAAR G  +  L  L N + D+N  +  G   LH A   G + +V  LL     + 
Sbjct: 14   TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
             + + G   LH A      E+VR L++YGA+    +  G T + M   E
Sbjct: 73   TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
            G T L  AA+  + EVV + LEN   + N     G+  L  A  +G  N+V HL+ YG  
Sbjct: 111  GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 169

Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
                           D   +A             + G  PLH A   ++L + +LLL+ G
Sbjct: 170  GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 229

Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
            A       +G T   I     + +M + L D    ++ +  D+
Sbjct: 230  ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 272


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
            L  A++ G+ ++V+  L  +I  +      G  ALH A   G   +VR L+ YGA+VN  
Sbjct: 49   LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 107

Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
            +Q G  PL+ A + +HLE+V+ LL  GA+  +AT  G T + +   +  E  +   +N
Sbjct: 108  SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
            AG T L  AAR G+ E VL  LE +          G+  LH A   G + +   LLE  A
Sbjct: 502  AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 560

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
              N + ++G  PLH AV +++L+IV+LLL  G  P    ++G T
Sbjct: 561  HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 604



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
            +   +G T L   A+ G+  V    +++ +  V+     GY  LH A   G + +V+ LL
Sbjct: 663  LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 721

Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            ++ ADVN   + G  PLH A +  H +IV LLL  GA P   +  G T
Sbjct: 722  QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            ET L  AAR G+ EV  Y L+NK   VN +       LH A   G  N+V+ LLE  A+ 
Sbjct: 438  ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            N +   G  PLH A    H+E V  LL   A     T  G T
Sbjct: 497  NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA  G +EVV   L N   +VN +   G+  L+ A     L +V+ LLE GA+
Sbjct: 78   GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
             N + +DG  PL  A++  H  +V  L++YG
Sbjct: 137  QNVATEDGFTPLAVALQQGHENVVAHLINYG 167



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 29/77 (37%), Positives = 39/77 (50%)

Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
            GY  LH A  +  + + R LL+YG   N  +  G  PLH A +  H E+V LLLS  A+ 
Sbjct: 602  GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661

Query: 1523 TLATYSGRTIMKMTHSE 1539
             L   SG T + +   E
Sbjct: 662  NLGNKSGLTPLHLVAQE 678



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA  G+  V    L+ K    N R   G+  LH AC +  + ++  LL+ GA ++
Sbjct: 340  TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
               + G  PLH A    HL IV+ LL  GA P ++     T + M     H+E + K+L 
Sbjct: 399  AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 457

Query: 1547 DYLNDLQGRNDDD 1559
                 +  +  DD
Sbjct: 458  QNKAKVNAKAKDD 470



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            +T L  AAR+G+  +V   LEN   + N    AG+  LH A   G +  V  LLE  A  
Sbjct: 471  QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 529

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
             C  + G  PLH A +   + +  LLL   A P  A  +G T + +   H+ L      D
Sbjct: 530  ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 583

Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
             +  L  R     S  W+ Y
Sbjct: 584  IVKLLLPRGGSPHSPAWNGY 603



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)

Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
            V    G T L  AA   YE + V   L N+   VN     G   LH A  RG + +VR L
Sbjct: 201  VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258

Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            L+ GA +    +D   PLH A  N H+ I  +LL +GA     T +G + + M
Sbjct: 259  LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 28/73 (38%), Positives = 39/73 (53%)

Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
            LH A   G   + ++LL+  A VN  A+D   PLH A    H  +V+LLL   A+P LAT
Sbjct: 441  LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500

Query: 1527 YSGRTIMKMTHSE 1539
             +G T + +   E
Sbjct: 501  TAGHTPLHIAARE 513



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)

Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
            +L++N+ A        G T L  A+R G   +++  L ++   +  +       LH A  
Sbjct: 223  QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 281

Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
             G + I   LL++GA +    ++G  P+H A + DHL+ VRLLL Y A+
Sbjct: 282  NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)

Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
            EA +  + K  G T L  AA+ G   V    LE      N     G   LH A     L+
Sbjct: 526  EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 583

Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
            IV+ LL  G   +  A +G  PLH A + + +E+ R LL YG      +  G T + +  
Sbjct: 584  IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 643

Query: 1537 ---HSELMEKFLTDYLN 1550
               H+E++   L+   N
Sbjct: 644  QEGHAEMVALLLSKQAN 660



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  A+  G  ++V + L+++  DVN +   GY  LH+A  +G  +IV  LL+ GA 
Sbjct: 701  GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
             N  + DGT PL  A    ++ +  +L
Sbjct: 760  PNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AAR G+  +    L++    +  +   G   +H A     L+ VR LL+Y A+++
Sbjct: 274  TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
                D   PLH A    H  + ++LL  GA P     +G T +    K  H  +ME  L
Sbjct: 333  DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA+ G+ E+V   L +K  + N  + +G   LH     G + +   L+++G  
Sbjct: 635  GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
            V+ + + G  PLH A    ++++V+ LL + AD    T  G + +     +     +T  
Sbjct: 694  VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753

Query: 1549 LNDLQGRNDDDASGT 1563
            L +    N+  + GT
Sbjct: 754  LKNGASPNEVSSDGT 768



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T   RAAR G  +  L  L N + D+N  +  G   LH A   G + +V  LL     + 
Sbjct: 14   TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
             + + G   LH A      E+VR L++YGA+    +  G T + M   E
Sbjct: 73   TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
            G T L  AA+  + EVV + LEN   + N     G+  L  A  +G  N+V HL+ YG  
Sbjct: 111  GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 169

Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
                           D   +A             + G  PLH A   ++L + +LLL+ G
Sbjct: 170  GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 229

Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
            A       +G T   I     + +M + L D    ++ +  D+
Sbjct: 230  ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 272


>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
          Length = 1719

 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
            L  A++ G+ ++V+  L  +I  +      G  ALH A   G   +VR L+ YGA+VN  
Sbjct: 49   LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 107

Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
            +Q G  PL+ A + +HLE+V+ LL  GA+  +AT  G T + +   +  E  +   +N
Sbjct: 108  SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
            AG T L  AAR G+ E VL  LE +          G+  LH A   G + +   LLE  A
Sbjct: 502  AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 560

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
              N + ++G  PLH AV +++L+IV+LLL  G  P    ++G T
Sbjct: 561  HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 604



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
            +   +G T L   A+ G+  V    +++ +  V+     GY  LH A   G + +V+ LL
Sbjct: 663  LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 721

Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            ++ ADVN   + G  PLH A +  H +IV LLL  GA P   +  G T
Sbjct: 722  QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            ET L  AAR G+ EV  Y L+NK   VN +       LH A   G  N+V+ LLE  A+ 
Sbjct: 438  ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            N +   G  PLH A    H+E V  LL   A     T  G T
Sbjct: 497  NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA  G +EVV   L N   +VN +   G+  L+ A     L +V+ LLE GA+
Sbjct: 78   GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
             N + +DG  PL  A++  H  +V  L++YG
Sbjct: 137  QNVATEDGFTPLAVALQQGHENVVAHLINYG 167



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 29/77 (37%), Positives = 39/77 (50%)

Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
            GY  LH A  +  + + R LL+YG   N  +  G  PLH A +  H E+V LLLS  A+ 
Sbjct: 602  GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661

Query: 1523 TLATYSGRTIMKMTHSE 1539
             L   SG T + +   E
Sbjct: 662  NLGNKSGLTPLHLVAQE 678



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA  G+  V    L+ K    N R   G+  LH AC +  + ++  LL+ GA ++
Sbjct: 340  TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
               + G  PLH A    HL IV+ LL  GA P ++     T + M     H+E + K+L 
Sbjct: 399  AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 457

Query: 1547 DYLNDLQGRNDDD 1559
                 +  +  DD
Sbjct: 458  QNKAKVNAKAKDD 470



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            +T L  AAR+G+  +V   LEN   + N    AG+  LH A   G +  V  LLE  A  
Sbjct: 471  QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 529

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
             C  + G  PLH A +   + +  LLL   A P  A  +G T + +   H+ L      D
Sbjct: 530  ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 583

Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
             +  L  R     S  W+ Y
Sbjct: 584  IVKLLLPRGGSPHSPAWNGY 603



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)

Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
            V    G T L  AA   YE + V   L N+   VN     G   LH A  RG + +VR L
Sbjct: 201  VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258

Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            L+ GA +    +D   PLH A  N H+ I  +LL +GA     T +G + + M
Sbjct: 259  LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 28/73 (38%), Positives = 39/73 (53%)

Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
            LH A   G   + ++LL+  A VN  A+D   PLH A    H  +V+LLL   A+P LAT
Sbjct: 441  LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500

Query: 1527 YSGRTIMKMTHSE 1539
             +G T + +   E
Sbjct: 501  TAGHTPLHIAARE 513



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)

Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
            +L++N+ A        G T L  A+R G   +++  L ++   +  +       LH A  
Sbjct: 223  QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 281

Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
             G + I   LL++GA +    ++G  P+H A + DHL+ VRLLL Y A+
Sbjct: 282  NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)

Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
            EA +  + K  G T L  AA+ G   V    LE      N     G   LH A     L+
Sbjct: 526  EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 583

Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
            IV+ LL  G   +  A +G  PLH A + + +E+ R LL YG      +  G T + +  
Sbjct: 584  IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 643

Query: 1537 ---HSELMEKFLTDYLN 1550
               H+E++   L+   N
Sbjct: 644  QEGHAEMVALLLSKQAN 660



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  A+  G  ++V + L+++  DVN +   GY  LH+A  +G  +IV  LL+ GA 
Sbjct: 701  GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
             N  + DGT PL  A    ++ +  +L
Sbjct: 760  PNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AAR G+  +    L++    +  +   G   +H A     L+ VR LL+Y A+++
Sbjct: 274  TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
                D   PLH A    H  + ++LL  GA P     +G T +    K  H  +ME  L
Sbjct: 333  DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA+ G+ E+V   L +K  + N  + +G   LH     G + +   L+++G  
Sbjct: 635  GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
            V+ + + G  PLH A    ++++V+ LL + AD    T  G + +     +     +T  
Sbjct: 694  VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753

Query: 1549 LNDLQGRNDDDASGT 1563
            L +    N+  + GT
Sbjct: 754  LKNGASPNEVSSDGT 768



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T   RAAR G  +  L  L N + D+N  +  G   LH A   G + +V  LL     + 
Sbjct: 14   TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
             + + G   LH A      E+VR L++YGA+    +  G T + M   E
Sbjct: 73   TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
            G T L  AA+  + EVV + LEN   + N     G+  L  A  +G  N+V HL+ YG  
Sbjct: 111  GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 169

Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
                           D   +A             + G  PLH A   ++L + +LLL+ G
Sbjct: 170  GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 229

Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
            A       +G T   I     + +M + L D    ++ +  D+
Sbjct: 230  ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 272


>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
          Length = 1856

 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)

Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
            L  A++ G+ ++V+  L  +I  +      G  ALH A   G   +VR L+ YGA+VN  
Sbjct: 49   LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 107

Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
            +Q G  PL+ A + +HLE+V+ LL  GA+  +AT  G T + +   +  E  +   +N
Sbjct: 108  SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)

Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
            AG T L  AAR G+ E VL  LE +          G+  LH A   G + +   LLE  A
Sbjct: 502  AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 560

Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
              N + ++G  PLH AV +++L+IV+LLL  G  P    ++G T
Sbjct: 561  HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 604



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)

Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
            +   +G T L   A+ G+  V    +++ +  V+     GY  LH A   G + +V+ LL
Sbjct: 663  LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 721

Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            ++ ADVN   + G  PLH A +  H +IV LLL  GA P   +  G T
Sbjct: 722  QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            ET L  AAR G+ EV  Y L+NK   VN +       LH A   G  N+V+ LLE  A+ 
Sbjct: 438  ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
            N +   G  PLH A    H+E V  LL   A     T  G T
Sbjct: 497  NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA  G +EVV   L N   +VN +   G+  L+ A     L +V+ LLE GA+
Sbjct: 78   GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
             N + +DG  PL  A++  H  +V  L++YG
Sbjct: 137  QNVATEDGFTPLAVALQQGHENVVAHLINYG 167



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 29/77 (37%), Positives = 39/77 (50%)

Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
            GY  LH A  +  + + R LL+YG   N  +  G  PLH A +  H E+V LLLS  A+ 
Sbjct: 602  GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661

Query: 1523 TLATYSGRTIMKMTHSE 1539
             L   SG T + +   E
Sbjct: 662  NLGNKSGLTPLHLVAQE 678



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AA  G+  V    L+ K    N R   G+  LH AC +  + ++  LL+ GA ++
Sbjct: 340  TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
               + G  PLH A    HL IV+ LL  GA P ++     T + M     H+E + K+L 
Sbjct: 399  AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 457

Query: 1547 DYLNDLQGRNDDD 1559
                 +  +  DD
Sbjct: 458  QNKAKVNAKAKDD 470



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)

Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
            +T L  AAR+G+  +V   LEN   + N    AG+  LH A   G +  V  LLE  A  
Sbjct: 471  QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 529

Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
             C  + G  PLH A +   + +  LLL   A P  A  +G T + +   H+ L      D
Sbjct: 530  ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 583

Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
             +  L  R     S  W+ Y
Sbjct: 584  IVKLLLPRGGSPHSPAWNGY 603



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)

Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
            V    G T L  AA   YE + V   L N+   VN     G   LH A  RG + +VR L
Sbjct: 201  VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258

Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
            L+ GA +    +D   PLH A  N H+ I  +LL +GA     T +G + + M
Sbjct: 259  LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 28/73 (38%), Positives = 39/73 (53%)

Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
            LH A   G   + ++LL+  A VN  A+D   PLH A    H  +V+LLL   A+P LAT
Sbjct: 441  LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500

Query: 1527 YSGRTIMKMTHSE 1539
             +G T + +   E
Sbjct: 501  TAGHTPLHIAARE 513



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)

Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
            +L++N+ A        G T L  A+R G   +++  L ++   +  +       LH A  
Sbjct: 223  QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 281

Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
             G + I   LL++GA +    ++G  P+H A + DHL+ VRLLL Y A+
Sbjct: 282  NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)

Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
            EA +  + K  G T L  AA+ G   V    LE      N     G   LH A     L+
Sbjct: 526  EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 583

Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
            IV+ LL  G   +  A +G  PLH A + + +E+ R LL YG      +  G T + +  
Sbjct: 584  IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 643

Query: 1537 ---HSELMEKFLTDYLN 1550
               H+E++   L+   N
Sbjct: 644  QEGHAEMVALLLSKQAN 660



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  A+  G  ++V + L+++  DVN +   GY  LH+A  +G  +IV  LL+ GA 
Sbjct: 701  GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
             N  + DGT PL  A    ++ +  +L
Sbjct: 760  PNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T L  AAR G+  +    L++    +  +   G   +H A     L+ VR LL+Y A+++
Sbjct: 274  TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
                D   PLH A    H  + ++LL  GA P     +G T +    K  H  +ME  L
Sbjct: 333  DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
            G T L  AA+ G+ E+V   L +K  + N  + +G   LH     G + +   L+++G  
Sbjct: 635  GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693

Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
            V+ + + G  PLH A    ++++V+ LL + AD    T  G + +     +     +T  
Sbjct: 694  VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753

Query: 1549 LNDLQGRNDDDASGT 1563
            L +    N+  + GT
Sbjct: 754  LKNGASPNEVSSDGT 768



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
            T   RAAR G  +  L  L N + D+N  +  G   LH A   G + +V  LL     + 
Sbjct: 14   TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72

Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
             + + G   LH A      E+VR L++YGA+    +  G T + M   E
Sbjct: 73   TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)

Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
            G T L  AA+  + EVV + LEN   + N     G+  L  A  +G  N+V HL+ YG  
Sbjct: 111  GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 169

Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
                           D   +A             + G  PLH A   ++L + +LLL+ G
Sbjct: 170  GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 229

Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
            A       +G T   I     + +M + L D    ++ +  D+
Sbjct: 230  ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,051,309
Number of Sequences: 37866
Number of extensions: 4577666
Number of successful extensions: 19742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 324
Number of HSP's successfully gapped in prelim test: 697
Number of HSP's that attempted gapping in prelim test: 15262
Number of HSP's gapped (non-prelim): 4675
length of query: 1721
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1605
effective length of database: 13,855,062
effective search space: 22237374510
effective search space used: 22237374510
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.