Guide to the Human Genome
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Search of human proteins with 209977080

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
         (553 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209977080 REST corepressor 3 isoform a [Homo sapiens]             1133   0.0  
gi|8922733 REST corepressor 3 isoform d [Homo sapiens]               1013   0.0  
gi|209977084 REST corepressor 3 isoform c [Homo sapiens]              899   0.0  
gi|209977082 REST corepressor 3 isoform b [Homo sapiens]              740   0.0  
gi|27734799 REST corepressor 2 [Homo sapiens]                         558   e-159
gi|7661892 REST corepressor 1 [Homo sapiens]                          506   e-143
gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens]          124   3e-28
gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens]          124   3e-28
gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo sapi...   124   3e-28
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...   115   1e-25
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...   112   9e-25
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             99   1e-20
gi|14141170 metastasis-associated protein 2 [Homo sapiens]             65   2e-10
gi|94721313 mesoderm induction early response 1, family member 3...    65   2e-10
gi|15812226 transcriptional regulating factor 1 [Homo sapiens]         64   3e-10
gi|210031154 zinc finger protein 541 [Homo sapiens]                    64   3e-10
gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens]    63   8e-10
gi|45267839 mesoderm induction early response 1, family member 2...    62   2e-09
gi|115527080 metastasis associated protein [Homo sapiens]              57   3e-08
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    56   1e-07
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    56   1e-07
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    54   4e-07
gi|153792074 proline rich 12 [Homo sapiens]                            54   4e-07
gi|116284392 mucin 2 precursor [Homo sapiens]                          53   8e-07
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     52   1e-06
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     52   1e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         52   1e-06
gi|160707881 formin 2 [Homo sapiens]                                   52   2e-06
gi|210032580 SET domain containing 1B [Homo sapiens]                   52   2e-06
gi|112807226 hypothetical protein LOC91748 [Homo sapiens]              52   2e-06

>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
          Length = 553

 Score = 1133 bits (2931), Expect = 0.0
 Identities = 553/553 (100%), Positives = 553/553 (100%)

Query: 1   MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60
           MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR
Sbjct: 1   MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60

Query: 61  VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120
           VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL
Sbjct: 61  VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120

Query: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180
           GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS
Sbjct: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180

Query: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240
           LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE
Sbjct: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240

Query: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300
           GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL
Sbjct: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300

Query: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360
           RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV
Sbjct: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360

Query: 361 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE 420
           RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE
Sbjct: 361 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE 420

Query: 421 ETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTL 480
           ETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTL
Sbjct: 421 ETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTL 480

Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 540
           PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS
Sbjct: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 540

Query: 541 LIGIQTDSQSSLH 553
           LIGIQTDSQSSLH
Sbjct: 541 LIGIQTDSQSSLH 553


>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
          Length = 495

 Score = 1013 bits (2620), Expect = 0.0
 Identities = 495/495 (100%), Positives = 495/495 (100%)

Query: 59  MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 118
           MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ
Sbjct: 1   MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 60

Query: 119 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 178
           ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI
Sbjct: 61  ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 120

Query: 179 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 238
           ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK
Sbjct: 121 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 180

Query: 239 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 298
           KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT
Sbjct: 181 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 240

Query: 299 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 358
           ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ
Sbjct: 241 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 300

Query: 359 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 418
           GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL
Sbjct: 301 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 360

Query: 419 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP 478
           GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP
Sbjct: 361 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP 420

Query: 479 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 538
           TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP
Sbjct: 421 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 480

Query: 539 PSLIGIQTDSQSSLH 553
           PSLIGIQTDSQSSLH
Sbjct: 481 PSLIGIQTDSQSSLH 495


>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
          Length = 449

 Score =  899 bits (2322), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60
           MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR
Sbjct: 1   MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60

Query: 61  VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120
           VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL
Sbjct: 61  VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120

Query: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180
           GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS
Sbjct: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180

Query: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240
           LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE
Sbjct: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240

Query: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300
           GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL
Sbjct: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300

Query: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360
           RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV
Sbjct: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360

Query: 361 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE 420
           RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE
Sbjct: 361 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE 420

Query: 421 ETKSASNVPSGKSTDEEEE 439
           ETKSASNVPSGKSTDEEEE
Sbjct: 421 ETKSASNVPSGKSTDEEEE 439


>gi|209977082 REST corepressor 3 isoform b [Homo sapiens]
          Length = 436

 Score =  740 bits (1911), Expect = 0.0
 Identities = 359/364 (98%), Positives = 360/364 (98%)

Query: 1   MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60
           MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR
Sbjct: 1   MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60

Query: 61  VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120
           VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDA+LDEYIAIAKEKHGYNVEQAL
Sbjct: 61  VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDARLDEYIAIAKEKHGYNVEQAL 120

Query: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180
           GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS
Sbjct: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180

Query: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240
           LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE
Sbjct: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240

Query: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300
           GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL
Sbjct: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300

Query: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360
           RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQG 
Sbjct: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGT 360

Query: 361 RKYG 364
              G
Sbjct: 361 DPTG 364



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 22/103 (21%), Positives = 47/103 (45%), Gaps = 2/103 (1%)

Query: 348 WTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQG 407
           WT E+++L  Q    +GK F  I  ++ +KT+  +  ++ ++++  +   ++     +  
Sbjct: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLA 206

Query: 408 TQASNGDASTLGEETKSASNVPSGKSTDEE--EEAQTPQAPRT 448
            + + GD+    EET       S     +E  +E  T Q  +T
Sbjct: 207 NRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQT 249


>gi|27734799 REST corepressor 2 [Homo sapiens]
          Length = 523

 Score =  558 bits (1439), Expect = e-159
 Identities = 311/552 (56%), Positives = 387/552 (70%), Gaps = 48/552 (8%)

Query: 1   MPGMMEK---GPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDV 57
           MP +MEK   G  +L ++R+                +  NGG  +SE +S    +  HD 
Sbjct: 1   MPSVMEKPSAGSGILSRSRAK---------------TVPNGGQPHSEDDSS-EEEHSHDS 44

Query: 58  GMRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNV 116
            +RVG  YQA IPE  P +  +Y++K+  GMLVWSP H + DAKLD+YIA+AKEKHGYN+
Sbjct: 45  MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNI 104

Query: 117 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDK 176
           EQALGML WHKH++EKSLADL NFTPFPDEWTVEDKVLFEQAF FHGK F RIQQMLPDK
Sbjct: 105 EQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDK 164

Query: 177 TIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDP-KK 235
            I SLVKYYYSWKKTRSRTS+MDRQAR+L  R ++ DS D++EE     G  S+ +P   
Sbjct: 165 LIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR---GGVSEGEPDPA 220

Query: 236 EAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNA 295
           + K+E    +P+  ++ G G++E Q  Q+RHH  R++ RPPKGMYL+ E + AVS SP+ 
Sbjct: 221 DPKREPLPSRPL-NARPGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDL 279

Query: 296 ANTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLL 355
           AN  LR LD +LISLKRQVQ+ KQ NS+L+Q +EGGI+  +PPE+N K N+RWTT+EQLL
Sbjct: 280 ANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLL 339

Query: 356 AVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDA 415
           AVQ +R+YGKDF AIA+VIGNKT+ QVK FFV+YRRRFNLEEVLQEWEAEQ        A
Sbjct: 340 AVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPG---A 396

Query: 416 STLGEETKSASNVPSGKSTDEEEEAQ----TPQAPRTLGPSPPAPSSTPTPTAPIATLNQ 471
               EE +  + +P+  + +E++E Q    +   PR++ P+PP P   P PT    +L+Q
Sbjct: 397 PVPMEEARRGAPLPA-PALEEDDEVQITSVSTSVPRSVPPAPPPP---PPPT----SLSQ 448

Query: 472 PPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 531
           PPPLLRP LP AP L RQPPPL QQ RF+QPR   NQPPPPLIRPA +  PR + RP   
Sbjct: 449 PPPLLRPPLPTAPTLLRQPPPL-QQGRFLQPRLAPNQPPPPLIRPALA-APRHSARP--- 503

Query: 532 TVGGQQPPSLIG 543
             G Q PP+LIG
Sbjct: 504 --GPQPPPTLIG 513


>gi|7661892 REST corepressor 1 [Homo sapiens]
          Length = 482

 Score =  506 bits (1302), Expect = e-143
 Identities = 266/425 (62%), Positives = 327/425 (76%), Gaps = 20/425 (4%)

Query: 19  NGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVG-MRVGAEYQARIPEFDPG-- 75
           NG  KS A    +G SS+N    + E  SG SSD+EH  G MRVG +YQA +P+FDP   
Sbjct: 64  NGQNKSLAAAAPNGNSSSNS---WEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKL 120

Query: 76  ATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQALGMLFWHKHNIEKSLA 135
           A +  ++DN GMLVWSP  ++ +AKLDEYIAIAKEKHGYN+EQALGMLFWHKHNIEKSLA
Sbjct: 121 ARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLA 180

Query: 136 DLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRT 195
           DLPNFTPFPDEWTVEDKVLFEQAFSFHGK+FHRIQQMLPDK+IASLVK+YYSWKKTR++T
Sbjct: 181 DLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKT 240

Query: 196 SLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLG 255
           S+MDR ARK   +  + +S+D++EE +  +  D + D  KE+KKE    + V   K    
Sbjct: 241 SVMDRHARK--QKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVK---- 294

Query: 256 RREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQ 315
            +E  S Q ++   R+K +PPKGM+L+QEDV AVS +  AA T+LRQLDMEL+S+KRQ+Q
Sbjct: 295 -KEKHSTQAKN---RAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQ 350

Query: 316 NAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIG 375
           N KQ NSALK+K++GGIE ++ PE  QK NARWTTEEQLLAVQ +RKYG+DFQAI+DVIG
Sbjct: 351 NIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIG 410

Query: 376 NKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKSTD 435
           NK+V QVKNFFVNYRRRFN++EVLQEWEAE G + +NG ++   +  KS  N  S K  +
Sbjct: 411 NKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQ--KPVKSPDN--SIKMPE 466

Query: 436 EEEEA 440
           EE+EA
Sbjct: 467 EEDEA 471


>gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens]
          Length = 266

 Score =  124 bits (310), Expect = 3e-28
 Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%)

Query: 59  MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 117
           +RVG  YQA IPE  P +  +Y++K   G+LVWSP H + DAKLD+YI +A EKHGYN+E
Sbjct: 2   VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61

Query: 118 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 177
           Q LG+    +  +   L  LP        W                     IQQ LPDK 
Sbjct: 62  QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94

Query: 178 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 236
           I+SLVKY+YSWKKT SRTS+ DRQAR+L    ++ DSD+  E    +   + D   PK+E
Sbjct: 95  ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%)

Query: 366 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 425
           DF AIA+VIGNKT+ QVK FFV+Y   FNLEEVLQEWEAEQ    + G    + E  + A
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226

Query: 426 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 464
             +    + +E+ E Q      ++  S PP  +  P PT+
Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264


>gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens]
          Length = 266

 Score =  124 bits (310), Expect = 3e-28
 Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%)

Query: 59  MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 117
           +RVG  YQA IPE  P +  +Y++K   G+LVWSP H + DAKLD+YI +A EKHGYN+E
Sbjct: 2   VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61

Query: 118 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 177
           Q LG+    +  +   L  LP        W                     IQQ LPDK 
Sbjct: 62  QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94

Query: 178 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 236
           I+SLVKY+YSWKKT SRTS+ DRQAR+L    ++ DSD+  E    +   + D   PK+E
Sbjct: 95  ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%)

Query: 366 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 425
           DF AIA+VIGNKT+ QVK FFV+Y   FNLEEVLQEWEAEQ    + G    + E  + A
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226

Query: 426 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 464
             +    + +E+ E Q      ++  S PP  +  P PT+
Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264


>gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo
           sapiens]
          Length = 266

 Score =  124 bits (310), Expect = 3e-28
 Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%)

Query: 59  MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 117
           +RVG  YQA IPE  P +  +Y++K   G+LVWSP H + DAKLD+YI +A EKHGYN+E
Sbjct: 2   VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61

Query: 118 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 177
           Q LG+    +  +   L  LP        W                     IQQ LPDK 
Sbjct: 62  QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94

Query: 178 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 236
           I+SLVKY+YSWKKT SRTS+ DRQAR+L    ++ DSD+  E    +   + D   PK+E
Sbjct: 95  ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%)

Query: 366 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 425
           DF AIA+VIGNKT+ QVK FFV+Y   FNLEEVLQEWEAEQ    + G    + E  + A
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226

Query: 426 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 464
             +    + +E+ E Q      ++  S PP  +  P PT+
Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score =  115 bits (287), Expect = 1e-25
 Identities = 107/410 (26%), Positives = 167/410 (40%), Gaps = 39/410 (9%)

Query: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 203
           W+ ++K  F + F  H K+F  I   L  KT+A  V YYY  KK  +  SL+ R  R   
Sbjct: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491

Query: 204 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSLQ 263
           K   +  Q       ++  PM  +  +   +KE +KE   E+          + E ++  
Sbjct: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEE---------KPEVEN-- 540

Query: 264 HRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNSA 323
            +    + K     G    +++ VA S     AN+  R+       + R + N      A
Sbjct: 541 DKEDLLKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANSEEA 595

Query: 324 LKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVK 383
           +  +    +   +  ES+     RWT EE   A +G+ ++G+++ AIA ++G+KTV Q K
Sbjct: 596 ITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCK 650

Query: 384 NFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------PSGK 432
           NF+ NY++R NL+E+LQ+     E E+  +     A     E  +   V        SG 
Sbjct: 651 NFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGV 710

Query: 433 STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP 492
           S +EEE  +  +A         +  S  T  A     N P P         P     PPP
Sbjct: 711 SGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPP 770

Query: 493 LQQQARFIQPRP---TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539
               A   +P P       P PP   P+ S PP + P+          PP
Sbjct: 771 EDIPAP-TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPP 819



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 89/439 (20%), Positives = 152/439 (34%), Gaps = 108/439 (24%)

Query: 147  WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLA 206
            WT E+    ++    HG+++  I +M+  KT++    +Y+++KK ++   ++ +   K+ 
Sbjct: 615  WTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKME 674

Query: 207  NRHN--------------------------------QGDSDDDVEETHPMDGNDSDYD-- 232
               N                                 G+ ++ VEE      N SD +  
Sbjct: 675  KERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESI 734

Query: 233  --PKKEAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVS 290
              P  EA K+     P   + +G                     PP G      + +   
Sbjct: 735  PSPHTEAAKDTGQNGPKPPATLGADG------------------PPPGPPTPPPEDIPAP 776

Query: 291  CSPNAANTILRQLDMELISLKRQV------QNAKQVNSALKQKMEGGIEEFKPPESNQKI 344
              P  A+                       +  K+  +A    +E G EE KPP + +  
Sbjct: 777  TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG-EEQKPPAAEELA 835

Query: 345  NARWTTEEQLL------AVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEV 398
                  EE +       A +G  K GKD +A                          E  
Sbjct: 836  VDTGKAEEPVKSECTEEAEEGPAK-GKDAEAA---------------------EATAEGA 873

Query: 399  LQEWEAEQGT-QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPS 457
            L+  + E G+ +A+   +S   +++ S++      S DE +EA+     R L P P    
Sbjct: 874  LKAEKKEGGSGRATTAKSSGAPQDSDSSATC----SADEVDEAEGGDKNRLLSPRP---- 925

Query: 458  STPTPTA-PIATLNQPPPL----LRPTLPAAPALH--RQPPPLQQQARFIQPRPTLNQPP 510
            S  TPT  P A  +   PL    L+    A P +   +   P ++ A   +P P    PP
Sbjct: 926  SLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPA-PPP 984

Query: 511  PPLIRPANSMP--PRLNPR 527
            P  ++P +  P  P  +PR
Sbjct: 985  PQNLQPESDAPQQPGSSPR 1003



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 6/118 (5%)

Query: 406  QGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPSSTP 460
            Q  Q  +      G   +  S  P+  +  E E+     A   +A +  G  P   S  P
Sbjct: 986  QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLP 1045

Query: 461  TPTAPIATLNQPPPLLRPT-LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPA 517
             P  P   +   P    P+    AP  H  P  L   AR + PRP     PPPLI  A
Sbjct: 1046 FPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1103


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score =  112 bits (280), Expect = 9e-25
 Identities = 105/410 (25%), Positives = 167/410 (40%), Gaps = 49/410 (11%)

Query: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 203
           W+ ++K  F + F  H K+F  I   L  KT+A  V YYY  KK  +  SL+ R  R   
Sbjct: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491

Query: 204 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSLQ 263
           K   +  Q       ++  PM  +  +   +KE +KE   E+          + E ++  
Sbjct: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEE---------KPEVEN-- 540

Query: 264 HRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNSA 323
            +    + K     G    +++ VA S     AN+  R+       + R + N      A
Sbjct: 541 DKEDLLKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANSEEA 595

Query: 324 LKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVK 383
           +  +    +   +  ES+     RWT EE   A +G+ ++G+++ AIA ++G+KTV Q K
Sbjct: 596 ITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCK 650

Query: 384 NFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------PSGK 432
           NF+ NY++R NL+E+LQ+     E E+  +     A     E  +   V        SG 
Sbjct: 651 NFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGV 710

Query: 433 STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP 492
           S +EEE  +  +A    G   P    +   T   ++  +  P   P   AA    +  P 
Sbjct: 711 SGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIP--SPHTEAAKDTGQNGP- 767

Query: 493 LQQQARFIQPRPTL---NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539
                   +P  TL     PP P   P   +P    P P     G   PP
Sbjct: 768 --------KPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP 809



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 6/118 (5%)

Query: 406  QGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPSSTP 460
            Q  Q  +      G   +  S  P+  +  E E+     A   +A +  G  P   S  P
Sbjct: 1002 QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLP 1061

Query: 461  TPTAPIATLNQPPPLLRPT-LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPA 517
             P  P   +   P    P+    AP  H  P  L   AR + PRP     PPPLI  A
Sbjct: 1062 FPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1119



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 13/138 (9%)

Query: 401  EWEAEQGTQASNGDASTLGEETKSASNVPSGK------STDEEEEAQTPQAPRTLGPSPP 454
            E  AE   +A   +  +    T  +S  P         S DE +EA+     R L P P 
Sbjct: 884  EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPS 943

Query: 455  APSSTPTPTAPIATLNQPPPLLRPTLPAA---PALHRQPPPLQQQARFIQPRPTLNQPPP 511
              + T  P A  A+  +P  L +    AA   P + +   P ++ A   +P P    PPP
Sbjct: 944  LLTPTGDPRAN-ASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA-PPPP 1001

Query: 512  PLIRPANSMP--PRLNPR 527
              ++P +  P  P  +PR
Sbjct: 1002 QNLQPESDAPQQPGSSPR 1019



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 12/83 (14%)

Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLL----- 476
           T  A   P G  T   E+   P  P     +  AP+  P P +P A    PPP++     
Sbjct: 772 TLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA----PPPVVPKEEK 827

Query: 477 RPTLPAAPAL---HRQPPPLQQQ 496
                AAP +     Q PP  ++
Sbjct: 828 EEETAAAPPVEEGEEQKPPAAEE 850


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 87/353 (24%), Positives = 151/353 (42%), Gaps = 31/353 (8%)

Query: 143 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQA 202
           F + WT  +K +F+  F  H K+F  I   L  K++   V YYY  KK  +  +L+ R  
Sbjct: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495

Query: 203 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 262
            K   R+ Q       E+    + + ++   KKE +K+   E+  +              
Sbjct: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEK-------------- 541

Query: 263 QHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNS 322
           +    + + K +       T+E   A       AN+  R+      S+  +   A    +
Sbjct: 542 EDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAA 601

Query: 323 ALKQKMEGGIEEFKPPESNQKIN-ARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQ 381
           A  ++    +     P S + +  +RWT EE  +A +G+ ++G+++ AIA ++G K+  Q
Sbjct: 602 AATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQ 661

Query: 382 VKNFFVNYRRRFNLEEVLQEWE--------AEQGTQASNGDASTLG---EETKSASNVPS 430
            KNF+ NY+RR NL+ +LQ+ +         E+        AST+    +E   ASN   
Sbjct: 662 CKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEE 721

Query: 431 GKSTDEEEEAQ----TPQAPRTLGPSPPAPSSTP-TPTAPIATLNQPPPLLRP 478
                E E  +    +P+   + G + PA    P T TAP  + +   P  +P
Sbjct: 722 NPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKP 774


>gi|14141170 metastasis-associated protein 2 [Homo sapiens]
          Length = 668

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 44/167 (26%), Positives = 81/167 (48%), Gaps = 34/167 (20%)

Query: 59  MRVGAEYQARIPE-FDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKE------- 110
           +RVG +YQA IP+    G +   ++    M VW P + + D ++D+++ +A+        
Sbjct: 147 IRVGCKYQAEIPDRLVEGESDNRNQQKMEMKVWDPDNPLTDRQIDQFLVVARAVGTFARA 206

Query: 111 -------------------KHGYNVEQALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145
                                   +  A+  L  + +++ K+++ L P   P       +
Sbjct: 207 LDCSSSIRQPSLHMSAAAASRDITLFHAMDTLQRNGYDLAKAMSTLVPQGGPVLCRDEME 266

Query: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191
           EW+  + +LFE+A   +GK F+ I+Q  LP K++AS+V++YY WK T
Sbjct: 267 EWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTT 313



 Score = 29.6 bits (65), Expect = 7.5
 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 3/61 (4%)

Query: 348 WTTEEQLLAVQGVRKYGKDFQAI-ADVIGNKTVGQVKNFFVNYRR--RFNLEEVLQEWEA 404
           W+  E +L  + + KYGKDF  I  D +  K++  +  F+  ++   R+  ++ L+  EA
Sbjct: 268 WSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEA 327

Query: 405 E 405
           +
Sbjct: 328 D 328


>gi|94721313 mesoderm induction early response 1, family member 3
           [Homo sapiens]
          Length = 549

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 33/210 (15%)

Query: 44  EPESGCSSDDEHDVGMRVGAEYQARIP----EFDPGATKYTDKDNGGMLVWSPYHSIPDA 99
           E +SG S +D     M +G +YQA IP    E+D     Y ++D    L+W P   + ++
Sbjct: 162 ETDSGNSPEDLRKEIM-IGLQYQAEIPPYLGEYDGNEKVYENEDQ---LLWCP-DVVLES 216

Query: 100 KLDEYIA--------------IAKEKHGYNVEQALGMLFWHKHNIEKSLADL---PNFTP 142
           K+ EY+               I+   H  + EQAL  L    HNI++++         + 
Sbjct: 217 KVKEYLVETSLRTGSEKIMDRISAGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQ 276

Query: 143 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKTRSRTSLMDRQ 201
               WT E+   FE A    GK FH IQ+  +  +T+A  V +YY WKK+  R     +Q
Sbjct: 277 GMTAWTEEECRSFEHALMLFGKDFHLIQKNKVRTRTVAECVAFYYMWKKS-ERYDYFAQQ 335

Query: 202 ARKLANRHNQGDSDDD-----VEETHPMDG 226
            R    R+N      D     V+ET  + G
Sbjct: 336 TRFGKKRYNHHPGVTDYMDRLVDETEALGG 365


>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
          Length = 1200

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 28/210 (13%)

Query: 59  MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYI--------AIAKE 110
           + +G  +QA IPE    +    D      LVW P+  + +  L + +        + A  
Sbjct: 781 INIGLRFQAEIPELQDISALAQDTHKA-TLVWKPWPELENHDLQQRVENLLNLCCSSALP 839

Query: 111 KHGYNVEQALGMLFWHKHNIEKSLADLPNFTPF--------------PDEWTVEDKVLFE 156
             G N E AL  LF  K ++  +L  L    P                D+WT  ++ LF 
Sbjct: 840 GGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFN 899

Query: 157 QAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDD 216
           +A + + K F  +Q+M+  KT+A  V+YYY+WKK      L  +   +LA   +   + +
Sbjct: 900 KALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKI---MRLGRKHRTRLAEIIDDCVTSE 956

Query: 217 DVEETHPMDGNDSDYDPKKEAKKEGNTEQP 246
           + EE    +  D + D  +++ KE  +E P
Sbjct: 957 EEEELEEEEEEDPEED--RKSTKEEESEVP 984



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 5/152 (3%)

Query: 347  RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406
            +WT+ E+ L  + +  Y KDF  +  ++ +KTV Q   ++  +++   L    +   AE 
Sbjct: 889  KWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI 948

Query: 407  GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPI 466
                   +     EE +        KST +EEE++ P++P      PP P   PT   P+
Sbjct: 949  IDDCVTSEEEEELEEEEEEDPEEDRKST-KEEESEVPKSPE----PPPVPVLAPTEGPPL 1003

Query: 467  ATLNQPPPLLRPTLPAAPALHRQPPPLQQQAR 498
              L QP       +P   A+      L   AR
Sbjct: 1004 QALGQPSGSFICEMPNCGAVFSSRQALNGHAR 1035



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 32/137 (23%), Positives = 45/137 (32%), Gaps = 40/137 (29%)

Query: 435 DEEEEAQTPQAPRTLGPSPPAPSSTPTP------TAPIATLNQPPPLLRP---------T 479
           +E E+   PQ    L P PP P     P      T  +  ++ P  LL P         +
Sbjct: 546 EEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNS 605

Query: 480 LPAAPALHRQP----------------------PPLQQQARFIQPRPTLNQPPPPLIRPA 517
             AAP+   +P                      P  ++  + +Q +      P PL  P 
Sbjct: 606 TVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPP 665

Query: 518 NSMPPRLNPRPVLSTVG 534
              PP  NP P  S  G
Sbjct: 666 ---PPSYNPNPAASYSG 679


>gi|210031154 zinc finger protein 541 [Homo sapiens]
          Length = 1365

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 48/155 (30%), Positives = 72/155 (46%), Gaps = 24/155 (15%)

Query: 59   MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPY-----HSIPDAKLDEYIAIAKEK-- 111
            + +G+ +QA IPE    +   TD ++   LVW P+      S    ++ E   +A     
Sbjct: 1074 INIGSRFQAEIPELQERSLAGTD-EHVASLVWKPWGDMMISSETQDRVTELCNVACSSVM 1132

Query: 112  --HGYNVEQALGMLFWHKHNIEKSLADLPNFTPFP--------------DEWTVEDKVLF 155
               G N+E AL  L   + N++ +L  L    P                D WT  +K LF
Sbjct: 1133 PGGGTNLELALHCLHEAQGNVQVALETLLLRGPHKPRTHLLADYRYTGSDVWTPIEKRLF 1192

Query: 156  EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 190
            ++AF  H K F+ I +M+  KT+A  V+YYY WKK
Sbjct: 1193 KKAFYAHKKDFYLIHKMIQTKTVAQCVEYYYIWKK 1227


>gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens]
          Length = 515

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 34/167 (20%)

Query: 59  MRVGAEYQARIPEFD-PGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 114
           +RVG  YQA IPE    G +   ++    + VW P   + D ++D+++ +A+    +   
Sbjct: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209

Query: 115 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145
                +V Q                  A+  L+ H +++  +++ L P   P       +
Sbjct: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269

Query: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191
           EW+  +  LFE+A   +GK F+ I+Q  LP K++ S+++YYY WK T
Sbjct: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316


>gi|45267839 mesoderm induction early response 1, family member 2
           [Homo sapiens]
          Length = 545

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 59/214 (27%), Positives = 93/214 (43%), Gaps = 32/214 (14%)

Query: 44  EPESGCSSDDEHDV--------GMRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHS 95
           EP S  SSD E D          + VG ++QA +             +N   L+W P   
Sbjct: 174 EPGSSASSDTEEDSLPANKCKKEIMVGPQFQADLSNLHLNRHCEKIYENEDQLLWDP-SV 232

Query: 96  IPDAKLDEYIAIAKEKHGYNV--------------EQALGMLFWHKHNIEKSLADLP-NF 140
           +P+ +++E++  A ++  + +              EQAL  L     N+E++L  L  N 
Sbjct: 233 LPEREVEEFLYRAVKRRWHEMAGPQLPEGEAVKDSEQALYELVKCNFNVEEALRRLRFNV 292

Query: 141 TPFPD---EWTVEDKVLFEQAFSFHGKSFHRIQ-QMLPDKTIASLVKYYYSWKKTRSRTS 196
               D    W+ E+   FE  F  HGK+FH IQ   +  +++   V+YYY WKK+  R  
Sbjct: 293 KVIRDGLCAWSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKS-ERYD 351

Query: 197 LMDRQARKLANRHNQGDSDDDVEETHPMDGNDSD 230
              +Q R L  R        D ++   +DG+D D
Sbjct: 352 YFAQQTR-LGRRKYVPSGTTDADQ--DLDGSDPD 382



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 22/183 (12%)

Query: 348 WTTEEQLLAVQGVRKYGKDFQAI-ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406
           W+ EE      G R +GK+F  I A+ +  ++VG+   ++  +++    +   Q+     
Sbjct: 302 WSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQ----- 356

Query: 407 GTQASNGDASTLGEETKSASNVPSGKS-TDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAP 465
                    + LG        VPSG +  D++ +   P  P    P P   + T   T P
Sbjct: 357 ---------TRLGRR----KYVPSGTTDADQDLDGSDPDGPGR--PRPEQDTLTGMRTDP 401

Query: 466 IATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLN 525
           ++       L  P + +      +P P   Q     P   L+  PP L  PA+  P    
Sbjct: 402 LSVDGTAGGLDEPGVASDGLPSSEPGPCSFQQLDESPAVPLSHRPPALADPASYQPAVTA 461

Query: 526 PRP 528
           P P
Sbjct: 462 PEP 464


>gi|115527080 metastasis associated protein [Homo sapiens]
          Length = 715

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 34/167 (20%)

Query: 59  MRVGAEYQARIPEF-DPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 114
           +RVG  YQA I +    G     D+      VW  ++ + D ++D+++ +A+    +   
Sbjct: 167 IRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARA 226

Query: 115 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145
                +V Q                  A+  L  + ++I K+++ L P   P       +
Sbjct: 227 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEME 286

Query: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191
           EW+  +  LFE+A   +GK F  IQQ  LP K++ S+++YYY WK T
Sbjct: 287 EWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTT 333


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 64/247 (25%), Positives = 97/247 (39%), Gaps = 42/247 (17%)

Query: 308 ISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVR--KYGK 365
           +S K++ + A    + +  K   G   F P + N  + A+ +  E     + V+  K   
Sbjct: 399 LSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAP 458

Query: 366 DFQAI------ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG 419
           D + +       +V  +   G+VK          N E+ L +    QGT+ S   A  L 
Sbjct: 459 DTELVNVTHLNTEVKNSSDTGKVK-------LDENSEKHLVKDLKAQGTRDSKPIA--LK 509

Query: 420 EETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPT 479
           EE      + + K T+  E+   P  P    P PP P++TP P        Q PPL  P 
Sbjct: 510 EE------IVTPKETETSEKETPPPLPTIASPPPPLPTTTPPP--------QTPPL--PP 553

Query: 480 LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539
           LP  PAL +QPP    Q  F Q   +     PP      S          +S+    QPP
Sbjct: 554 LPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTS---------AVSSQANSQPP 604

Query: 540 SLIGIQT 546
             + ++T
Sbjct: 605 VQVSVKT 611



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 39/161 (24%), Positives = 56/161 (34%), Gaps = 21/161 (13%)

Query: 379  VGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG--EETKSASN----VPSGK 432
            + Q+ N   N   +  LE + Q   A     +   D+ T+   E  K A +    +PS +
Sbjct: 1134 MAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAE 1193

Query: 433  STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPP------PLLRPTLPAAPAL 486
             T  E  +        L         T  P   +   N         P   PT+P   A 
Sbjct: 1194 QTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAA 1253

Query: 487  HRQPPPLQQQARFIQPRPTLNQPPPPLIR-PANSMPPRLNP 526
             ++PP          P P    PPPPL+    +S P  LNP
Sbjct: 1254 EKRPPE--------PPGPPPPPPPPPLVEGDLSSAPQELNP 1286


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 64/247 (25%), Positives = 97/247 (39%), Gaps = 42/247 (17%)

Query: 308 ISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVR--KYGK 365
           +S K++ + A    + +  K   G   F P + N  + A+ +  E     + V+  K   
Sbjct: 399 LSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAP 458

Query: 366 DFQAI------ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG 419
           D + +       +V  +   G+VK          N E+ L +    QGT+ S   A  L 
Sbjct: 459 DTELVNVTHLNTEVKNSSDTGKVK-------LDENSEKHLVKDLKAQGTRDSKPIA--LK 509

Query: 420 EETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPT 479
           EE      + + K T+  E+   P  P    P PP P++TP P        Q PPL  P 
Sbjct: 510 EE------IVTPKETETSEKETPPPLPTIASPPPPLPTTTPPP--------QTPPL--PP 553

Query: 480 LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539
           LP  PAL +QPP    Q  F Q   +     PP      S          +S+    QPP
Sbjct: 554 LPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTS---------AVSSQANSQPP 604

Query: 540 SLIGIQT 546
             + ++T
Sbjct: 605 VQVSVKT 611



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 26/78 (33%), Positives = 28/78 (35%), Gaps = 24/78 (30%)

Query: 453  PPAPSSTPTPTAPIATLNQP---PPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQP 509
            P  P  TPT     A    P   PP  RP  P  P     PPP                P
Sbjct: 1238 PQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGP-----PPP---------------PP 1277

Query: 510  PPPLIR-PANSMPPRLNP 526
            PPPL+    +S P  LNP
Sbjct: 1278 PPPLVEGDLSSAPQELNP 1295


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 51/167 (30%), Positives = 70/167 (41%), Gaps = 34/167 (20%)

Query: 403 EAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPS 457
           E+E  +++S+ D+     E    S        ++++       Q  QAP  +   PP P 
Sbjct: 702 ESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPP 761

Query: 458 STPTPTAPIATLNQ-PPPLLRPTLP--AAPALHRQPPP--------LQQQ---------A 497
             P P  P     Q PPP   P++P  AAPA+   PPP        L+ Q          
Sbjct: 762 QQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIG 821

Query: 498 RFIQPRPTLNQP--PPPLIR-PANSMPPRLNPRPVLSTVGGQQPPSL 541
            F QP   L QP  PP L + P +S PP LN   V+S      PP+L
Sbjct: 822 HFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVS------PPAL 862



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 34/109 (31%), Positives = 40/109 (36%), Gaps = 19/109 (17%)

Query: 438  EEAQTPQAPRTLGPS-------PPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP 490
            ++ Q  Q P  L PS       PP     P P+       QPPP   P     P    QP
Sbjct: 933  QQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQP 992

Query: 491  PPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539
            PP     + +Q    + QPPP    P    PP   P        GQQPP
Sbjct: 993  PPRPVHLQPMQFSTHIQQPPP----PQGQQPPHPPP--------GQQPP 1029



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 42/159 (26%), Positives = 61/159 (38%), Gaps = 26/159 (16%)

Query: 405  EQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTL--GPSPPAPSST--- 459
            +Q ++ SN  A+   +  +  +  P+   T    +    Q P+ L     PPAP  T   
Sbjct: 868  QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927

Query: 460  -------------PTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTL 506
                         PTP  P   +   PP   P LP  P      P +QQQ +   P P  
Sbjct: 928  MQLYLQQLQKVQPPTPLLPSVKVQSQPP---PPLPPPPH-----PSVQQQLQQQPPPPPP 979

Query: 507  NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGIQ 545
             QP PP  +     P  ++ +P+  +   QQPP   G Q
Sbjct: 980  PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQ 1018



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 1/85 (1%)

Query: 443  PQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQP 502
            P   + L   PP P   P P  P    +QPPP      P   + H Q PP  Q  +   P
Sbjct: 964  PSVQQQLQQQPPPPPP-PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHP 1022

Query: 503  RPTLNQPPPPLIRPANSMPPRLNPR 527
             P    PPP   +P   +    +PR
Sbjct: 1023 PPGQQPPPPQPAKPQQVIQHHHSPR 1047



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 30/149 (20%)

Query: 419 GEETKSASNVPSGKST-DEEEEAQTPQAPRTLGPSPPAPSSTPTP----------TAPIA 467
           G   K       G ST     +A TP   +T  P+PP   +TP P            P+ 
Sbjct: 180 GRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVM 239

Query: 468 TLNQPPPLLRPTLPAAPALHRQPP-----PLQQQARFIQPRP-----------TLNQPPP 511
           T+  P PL  P  P  P   + PP     P+Q     I   P             +   P
Sbjct: 240 TVVPPQPLQTP--PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297

Query: 512 PLIRPANSMPPRLNPRPVLSTVGGQQPPS 540
             I P +  PP L P P  + +G ++  S
Sbjct: 298 TTIDPIHE-PPSLPPEPKTTKLGQRRESS 325



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 18/96 (18%)

Query: 451 PSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALH----RQPPPLQQQARFIQPRPTL 506
           P P  P   P P       + PP L +  + + PALH    +QP     +A  + P+P  
Sbjct: 831 PQPELPPHLPQPPEH----STPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA- 885

Query: 507 NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 542
               PP + PA +  P L P+P ++     QPP ++
Sbjct: 886 ---RPPAVSPALTQTPLL-PQPPMA-----QPPQVL 912



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 27/109 (24%), Positives = 37/109 (33%), Gaps = 2/109 (1%)

Query: 436 EEEEAQTPQAP-RTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQ 494
           EE E    QA  R  G      +     T P  T    PP  +   P  P +   P P  
Sbjct: 167 EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP 226

Query: 495 QQAR-FIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 542
                 I   P +   PP  ++    +PP+  P P  +    Q  P +I
Sbjct: 227 AVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPII 275



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 32/118 (27%), Positives = 39/118 (33%), Gaps = 40/118 (33%)

Query: 453 PPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP----------------PPLQ-- 494
           P  PS      A +      PP + P L   P L + P                PPL   
Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSM 926

Query: 495 ------QQARFIQPRPTL-------NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539
                 QQ + +QP   L       +QPPPPL  P         P P +     QQPP
Sbjct: 927 QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPP---------PHPSVQQQLQQQPP 975


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 53/170 (31%), Positives = 69/170 (40%), Gaps = 30/170 (17%)

Query: 393  FNLEEVLQEWEAEQGTQASNGDASTLGEETK-SASNVPSGKSTDEEEEAQTPQAPRTLGP 451
            F L   L+  E+E            L EE K +   +PS  S +E+  A+      ++  
Sbjct: 1341 FGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400

Query: 452  S----------PPAPSSTPT--PTAPIATLNQPPPLLRPTLPAA--------PALHRQPP 491
            +           P  +STP   P AP A +  PPPL  P LP+A        P L  +PP
Sbjct: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPL--PGLPSANSNGTPEPPLLEEKPP 1458

Query: 492  PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSL 541
            P    A   QP+P    PPPP  +PA   PP L    V  T     PP L
Sbjct: 1459 PTPPPAPTPQPQP---PPPPPPPQPALPSPPPL----VAPTPSSPPPPPL 1501



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/86 (37%), Positives = 37/86 (43%), Gaps = 12/86 (13%)

Query: 436  EEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495
            EE+   TP    T  P PP P   P P  P      PPPL+ PT P++P     PPPL  
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPALP-----SPPPLVAPT-PSSPP----PPPLPP 1503

Query: 496  QARFIQPRPTLNQPPPPLIRPANSMP 521
                  P P    PPPP   P  + P
Sbjct: 1504 PPPPAMPSPP--PPPPPAAAPLAAPP 1527



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 31/81 (38%), Positives = 35/81 (43%), Gaps = 11/81 (13%)

Query: 442  TPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQ 501
            TP+ P      PP P   PTP        QPPP   P  PA P+    PPPL        
Sbjct: 1447 TPEPPLLEEKPPPTPPPAPTPQP------QPPPPPPPPQPALPS----PPPLVAPTPSSP 1496

Query: 502  PRPTLNQPPPPLIRPANSMPP 522
            P P L  PPPP + P+   PP
Sbjct: 1497 PPPPLPPPPPPAM-PSPPPPP 1516



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 40/153 (26%), Positives = 55/153 (35%), Gaps = 17/153 (11%)

Query: 394  NLEEVLQEWEAEQGTQASNGDAS-TLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPS 452
            NLE +      E+ + A N D   ++     +  + P     D       P AP    P 
Sbjct: 1373 NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG 1432

Query: 453  PP------APSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTL 506
            PP      + +S  TP  P+  L + PP   P  P        PPP         P+P L
Sbjct: 1433 PPPLPGLPSANSNGTPEPPL--LEEKPPPTPPPAPTPQPQPPPPPP--------PPQPAL 1482

Query: 507  NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539
              PPP +    +S PP   P P    +    PP
Sbjct: 1483 PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP 1515



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 6/84 (7%)

Query: 429  PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHR 488
            P    T + +    P  P+   PSPP P   PTP++P      PPPL  P  PA P+   
Sbjct: 1461 PPPAPTPQPQPPPPPPPPQPALPSPP-PLVAPTPSSP-----PPPPLPPPPPPAMPSPPP 1514

Query: 489  QPPPLQQQARFIQPRPTLNQPPPP 512
             PPP           P    P  P
Sbjct: 1515 PPPPAAAPLAAPPEEPAAPSPEDP 1538



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 18/112 (16%)

Query: 439 EAQTPQAPRTLGPSPP---------APSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQ 489
           EA  P  P  L P PP         APS  P+P+A    ++   P  R   P  P     
Sbjct: 784 EAGGPDLPLVLPPPPPQLLPSVLSHAPS--PSPSASKVGVHLLEPATRDGAPQPPPPPPP 841

Query: 490 PP---PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 538
           PP   PLQ +A  ++        P P +RP  S+ P   P  +   +G  +P
Sbjct: 842 PPPPMPLQLEAH-LRSHGLEPAAPSPRLRPEESLDP---PGAMQELLGALEP 889



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 9/101 (8%)

Query: 429  PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP--TAPIATLNQPPPLLRPTLPAAPAL 486
            P G       +A  P  P    P PPAP+S P    T+PI    +P  LL+ +  +   L
Sbjct: 1026 PLGLIQSGPHQAAPPPPPPP--PPPPAPASEPKGGLTSPIFCSTKPKKLLKTS--SFHLL 1081

Query: 487  HRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPR 527
             R+ PP Q   +                 PA+    RLNPR
Sbjct: 1082 RRRDPPFQTPKKLYAQEYEFEADEDKADVPADI---RLNPR 1119



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 12/125 (9%)

Query: 432  KSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPP 491
            K+T E+   QTP+   T  P PPAP   P+   P+    +   + R   P          
Sbjct: 1708 KTTSEKPPEQTPE---TAMPEPPAPEK-PSLLRPVEKEKEKEKVTRGERPLRGERATSGR 1763

Query: 492  PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQ-----PPSLIGIQT 546
              + +      +P  ++ P        + PP    +  L   GG       PP   G  +
Sbjct: 1764 QTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPP---GSSS 1820

Query: 547  DSQSS 551
            DS+SS
Sbjct: 1821 DSESS 1825



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 439  EAQTP-QAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP--TLPAAPA 485
            +A+ P  A  +  P P AP+  P P  P  T ++ PP   P   +P  PA
Sbjct: 1679 QAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPA 1728


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 42/151 (27%), Positives = 57/151 (37%), Gaps = 19/151 (12%)

Query: 402  WEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPP-----AP 456
            W  ++     +   +T      S + +P   +T       T   P T  PSPP      P
Sbjct: 1390 WPMDKCITTPSPPTTTPSPPPTSTTTLPP-TTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448

Query: 457  SSTPTPTAPIATLNQPPPLLRP----TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPP- 511
              T TP+ PI+T   PPP   P    T P+ P     PP          P PT    PP 
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT----PPPTTTPSPPT 1504

Query: 512  --PLIRPAN--SMPPRLNPRPVLSTVGGQQP 538
              P+  PA+  ++PP   P P  +T     P
Sbjct: 1505 TTPITPPASTTTLPPTTTPSPPTTTTTTPPP 1535



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 16/114 (14%)

Query: 433  STDEEEEAQTPQAPRTLGPSPP-----APSSTPTPTAPIATLNQPPPLLRPTLPAA---- 483
            ST       TP  P T   +PP     +P +T TP+ P  T   PPP   P+ P      
Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611

Query: 484  --PALHRQPP---PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLST 532
              P     PP   P+          PT    PPP      + PP   P P  +T
Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP--TTTTTPPPTTTPSPPTTT 1663



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 17/132 (12%)

Query: 424  SASNVPSGKSTDEEEEAQTPQAPRTLGPSPPA-----PSSTPTP-----TAPIATLNQPP 473
            + +  P   +T     + T   P T  PSPP      P++TP+P     T P  T    P
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502

Query: 474  PLLRPTLPAAPALHRQP--PPLQQQARFIQPRPTLNQPPP---PLIRPAN--SMPPRLNP 526
            P   P  P A      P   P         P PT    PP   P+  P +  ++PP   P
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562

Query: 527  RPVLSTVGGQQP 538
             P  +T     P
Sbjct: 1563 SPPPTTTTTPPP 1574



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 16/109 (14%)

Query: 440  AQTPQAPRTLGPSPPAPSST-PTPT---APIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495
            A T   P T  PSPP  ++T P PT   +P  T    PP    TLP  P     PPP   
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTT 1569

Query: 496  QARFIQPRPTLNQPPPPLIRPA------NSMPPRLNPRPVLSTVGGQQP 538
                  P PT    PP    P+       + PP   P P  +T     P
Sbjct: 1570 TT----PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 34/116 (29%), Positives = 41/116 (35%), Gaps = 17/116 (14%)

Query: 433  STDEEEEAQTPQAPRTLGPSPP-----APSSTPTPTAPIATLNQPPPLLRP-----TLPA 482
            ST       TP  P T   +PP     +P +T TP+ PI T   PPP   P     T P+
Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690

Query: 483  APALHRQPP-----PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTV 533
             P      P     P         P  T    PPP      S  P   P P  +T+
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS--PTTTPSPPTTTM 1744



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 34/110 (30%), Positives = 38/110 (34%), Gaps = 12/110 (10%)

Query: 429  PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHR 488
            P   +T       T   P T  PSPP    T T T P  T    PP   P  P  P    
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPP----TTTTTTPPPTTTPSPPTTTPITP--PTSTT 1633

Query: 489  QPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 538
              PP    +    P PT    PPP   P  S P    P P ++T     P
Sbjct: 1634 TLPPTTTPS----PPPTTTTTPPPTTTP--SPPTTTTPSPPITTTTTPPP 1677



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 14/115 (12%)

Query: 426  SNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPA 485
            +  P   +T       T   P T  PSPP    T TP  P  +    PP   P+ P  P 
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPP----TTTPITPPTSTTTLPPTTTPSPP--PT 1646

Query: 486  LHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 540
                PPP         P P     P P I    + PP   P   ++T     PP+
Sbjct: 1647 TTTTPPPT------TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT--PSPPT 1693



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 42/180 (23%), Positives = 56/180 (31%), Gaps = 17/180 (9%)

Query: 385  FFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQ 444
            F +NY       E + +      T   N    T    T + +  P+   T  +    TP 
Sbjct: 1865 FCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1924

Query: 445  APRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPR 503
               T     P P+ T TP T PI T     P   PT    P      P          P 
Sbjct: 1925 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPT 1981

Query: 504  PTLNQPP-----------PPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGIQTDSQSSL 552
            PT  Q P            P   P  +  P   P    +TV     P+  G QT + + +
Sbjct: 1982 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPTGTQTPTTTPI 2039



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 32/109 (29%), Positives = 41/109 (37%), Gaps = 11/109 (10%)

Query: 442  TPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP---LQQQAR 498
            TP   +T   +P   ++T TPT         PP    T P A      PPP     Q +R
Sbjct: 4166 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR 4225

Query: 499  F----IQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGG---QQPPS 540
                 +    TL    PP I   ++ PP   P    +T GG     PPS
Sbjct: 4226 STSSPLTESTTLLSTLPPAIEMTSTAPPS-TPTAPTTTSGGHTLSPPPS 4273



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 446  PRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495
            P T  P+P    STPTP+ P +T ++P P  +P  P  P      PP Q+
Sbjct: 4377 PSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKP--PECPDF---DPPRQE 4421



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 25/91 (27%), Positives = 32/91 (35%), Gaps = 8/91 (8%)

Query: 443  PQAPRTLGPSP-PAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQ 501
            P +  TL P+  P+P  T T T P  T   PP    P+ P        PPP    +    
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT--TTPPPTTTPS---- 1682

Query: 502  PRPTLNQPPPPLIRPANSMPPRLNPRPVLST 532
              P    P PP        P      P+ +T
Sbjct: 1683 -SPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 32/131 (24%), Positives = 46/131 (35%), Gaps = 8/131 (6%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTP-TPTAPIATLNQPPPLLRPTL 480
            T + +  P+G  T       T         +PP  SSTP T  +  + L +   LL    
Sbjct: 4183 TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 540
            PA       PP             TL+ PP        + PP    R   +T G    P+
Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPP-----STTTSPPGTPTRG--TTTGSSSAPT 4295

Query: 541  LIGIQTDSQSS 551
               +QT + S+
Sbjct: 4296 PSTVQTTTTSA 4306



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2017 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2076

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2077 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 2134 TTTV--TPTPTPTGTQTPTTTPI 2154



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2132 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2191

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2192 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 2249 TTTV--TPTPTPTGTQTPTTTPI 2269



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2247 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2306

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2307 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2363

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 2364 TTTV--TPTPTPTGTQTPTTTPI 2384



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2422 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 2479 TTTV--TPTPTPTGTQTPTTTPI 2499



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2536

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2537 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 2594 TTTV--TPTPTPTGTQTPTTTPI 2614



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2651

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2652 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 2709 TTTV--TPTPTPTGTQTPTTTPI 2729



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2767 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 2824 TTTV--TPTPTPTGTQTPTTTPI 2844



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2822 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2881

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2882 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 2939 TTTV--TPTPTPTGTQTPTTTPI 2959



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 2937 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2996

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 2997 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3054 TTTV--TPTPTPTGTQTPTTTPI 3074



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3111

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 3112 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3169 TTTV--TPTPTPTGTQTPTTTPI 3189



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3167 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3226

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 3227 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3284 TTTV--TPTPTPTGTQTPTTTPI 3304



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3341

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 3342 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3399 TTTV--TPTPTPTGTQTPTTTPI 3419



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3456

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 3457 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3514 TTTV--TPTPTPTGTQTPTTTPI 3534



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3512 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3571

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 3572 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3629 TTTV--TPTPTPTGTQTPTTTPI 3649



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3627 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3686

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 3687 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3744 TTTV--TPTPTPTGTQTPTTTPI 3764



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3742 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3801

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 3802 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3859 TTTV--TPTPTPTGTQTPTTTPI 3879



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3916

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 3917 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 3974 TTTV--TPTPTPTGTQTPTTTPI 3994



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 3972 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4031

Query: 481  PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529
               P      P          P PT  Q P            P   P  +  P   P   
Sbjct: 4032 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4088

Query: 530  LSTVGGQQPPSLIGIQTDSQSSL 552
             +TV     P+  G QT + + +
Sbjct: 4089 TTTV--TPTPTPTGTQTPTTTPI 4109



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 33/142 (23%), Positives = 42/142 (29%), Gaps = 12/142 (8%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480
            T + +  P+   T  +    TP    T     P P+ T TP T PI T     P   PT 
Sbjct: 4087 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4146

Query: 481  PAAP---------ALHRQPPPLQQQARFIQPRPTLN--QPPPPLIRPANSMPPRLNPRPV 529
               P          +   P P   Q     P  T     P P         P   +  P+
Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI 4206

Query: 530  LSTVGGQQPPSLIGIQTDSQSS 551
                    PP     QT   +S
Sbjct: 4207 AELTTSNPPPESSTPQTSRSTS 4228



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 23/73 (31%), Positives = 27/73 (36%), Gaps = 7/73 (9%)

Query: 409  QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAP------RTLGPSPPAPSSTP-T 461
            Q S   +S L E T   S +P            TP AP       TL P P   +S P T
Sbjct: 4222 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT 4281

Query: 462  PTAPIATLNQPPP 474
            PT    T +   P
Sbjct: 4282 PTRGTTTGSSSAP 4294



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 28/100 (28%), Positives = 32/100 (32%), Gaps = 25/100 (25%)

Query: 422  TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLP 481
            T S +  PS   T       TP +  T  P PP   +TP+PT    T   PP     TLP
Sbjct: 1698 TPSPTTTPSSPITT----TTTPSSTTTPSP-PPTTMTTPSPT----TTPSPPTTTMTTLP 1748

Query: 482  AAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMP 521
                                  P    P PP I P    P
Sbjct: 1749 PTTT----------------SSPLTTTPLPPSITPPTFSP 1772


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 75/303 (24%), Positives = 110/303 (36%), Gaps = 65/303 (21%)

Query: 276 PKGMYLTQEDVVAVSCSPNAANTIL--RQLDMELISLKRQVQNAKQVNSALKQKMEGGIE 333
           P+   L +E +  +    N A+     R L +E+  L  Q+ +  +V  +          
Sbjct: 419 PQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKS---------- 468

Query: 334 EFKPPESNQKINARWTTEEQLLAVQGVRKYGKDF-QAIADVIGNKTVGQVKNFFVNYRRR 392
           E K  E  +K+++  T   +L     ++K   DF Q + D+ G K           +  +
Sbjct: 469 EAKAAELEKKLDSELTARHELQVE--MKKMESDFEQKLQDLQGEKDA--------LHSEK 518

Query: 393 FNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKST-------DEEEEAQTPQA 445
             +    Q+ EAE       G+ + L +E + A    +  S             A  P A
Sbjct: 519 QQIATEKQDLEAE--VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 576

Query: 446 PR------TLGPSPPAPSSTPTPTAPIATLNQPPPL-------LRPTLPAAPALHRQPPP 492
           P       T+ P PPAP  + TP  P      PPPL         P+LP   A+   PPP
Sbjct: 577 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI-SPPPP 635

Query: 493 LQQQARFIQPRP----------------TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQ 536
           L   A    P P                T   PPPPL   A   PP   P P+  + G  
Sbjct: 636 LSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP---PPPLPGSAGIP 692

Query: 537 QPP 539
            PP
Sbjct: 693 PPP 695



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 21/112 (18%)

Query: 443 PQAPRTLGPSPPAPSSTPTPTA-------PIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495
           P  P   G   P+PSS P  TA       P +    PPP   P LP +  +   PPPL  
Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP---PPLPGSAGIPPPPPPLPG 700

Query: 496 QARFIQPRPTL----NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543
           +A    P P L      PPPP       +PP   P P +    G  PP   G
Sbjct: 701 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGM----GMPPPPPFG 745


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 75/303 (24%), Positives = 110/303 (36%), Gaps = 65/303 (21%)

Query: 276 PKGMYLTQEDVVAVSCSPNAANTIL--RQLDMELISLKRQVQNAKQVNSALKQKMEGGIE 333
           P+   L +E +  +    N A+     R L +E+  L  Q+ +  +V  +          
Sbjct: 428 PQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKS---------- 477

Query: 334 EFKPPESNQKINARWTTEEQLLAVQGVRKYGKDF-QAIADVIGNKTVGQVKNFFVNYRRR 392
           E K  E  +K+++  T   +L     ++K   DF Q + D+ G K           +  +
Sbjct: 478 EAKAAELEKKLDSELTARHELQVE--MKKMESDFEQKLQDLQGEKDA--------LHSEK 527

Query: 393 FNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKST-------DEEEEAQTPQA 445
             +    Q+ EAE       G+ + L +E + A    +  S             A  P A
Sbjct: 528 QQIATEKQDLEAE--VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 585

Query: 446 PR------TLGPSPPAPSSTPTPTAPIATLNQPPPL-------LRPTLPAAPALHRQPPP 492
           P       T+ P PPAP  + TP  P      PPPL         P+LP   A+   PPP
Sbjct: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI-SPPPP 644

Query: 493 LQQQARFIQPRP----------------TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQ 536
           L   A    P P                T   PPPPL   A   PP   P P+  + G  
Sbjct: 645 LSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP---PPPLPGSAGIP 701

Query: 537 QPP 539
            PP
Sbjct: 702 PPP 704



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 21/112 (18%)

Query: 443 PQAPRTLGPSPPAPSSTPTPTA-------PIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495
           P  P   G   P+PSS P  TA       P +    PPP   P LP +  +   PPPL  
Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP---PPLPGSAGIPPPPPPLPG 709

Query: 496 QARFIQPRPTL----NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543
           +A    P P L      PPPP       +PP   P P +    G  PP   G
Sbjct: 710 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGM----GMPPPPPFG 754


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 45/157 (28%), Positives = 65/157 (41%), Gaps = 19/157 (12%)

Query: 401 EWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSS-- 458
           E E  + +   NG+       + S S  PS +   +E    +P+  R   PSPP      
Sbjct: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET---SPRGRRRRSPSPPPTRRRR 559

Query: 459 TPTPTAPIATLNQPPPLLRPTLPAAPALHRQP------PPLQQQARFIQP--RPTLNQPP 510
           +P+P  P      P P  R   P+ P   R P      PP+Q++     P  R T + PP
Sbjct: 560 SPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619

Query: 511 PPLIRPANSMPPRLN------PRPVLSTVGGQQPPSL 541
           PP  R + S PP+        P+   S V  ++ PSL
Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 11/127 (8%)

Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPP----APSS-----TPTP-TAPIATLNQ 471
           ++S     S +       +  P+AP+T    PP    A SS     +P+P T PI  +++
Sbjct: 667 SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726

Query: 472 PPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 531
            P   +    A+P+          ++    P P   +PP P   P  S  P  N  P + 
Sbjct: 727 TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP-PSPVQSQSPSTNWSPAVP 785

Query: 532 TVGGQQP 538
               + P
Sbjct: 786 VKKAKSP 792



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 26/113 (23%), Positives = 38/113 (33%), Gaps = 5/113 (4%)

Query: 442 TPQAPRTLGPSPPAPS-STPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFI 500
           +P   R   PSPP    +   P  P    +  PP  R    + P   R  P  ++++  +
Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656

Query: 501 QPRPTLNQPPPPLIRPANSMPPRL----NPRPVLSTVGGQQPPSLIGIQTDSQ 549
             +      P    R A S  P      +PRP         PP   G  +  Q
Sbjct: 657 SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQ 709



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 27/110 (24%), Positives = 41/110 (37%), Gaps = 20/110 (18%)

Query: 443 PQAPRTLGPSPPAPS-STPTPTAPIATLNQPPPLLRPT------LPAAPALHRQ------ 489
           P   RT  P PP    ++P+P       + PPP  R +       P+  + HR+      
Sbjct: 609 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR 668

Query: 490 -------PPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLST 532
                  P P ++ +   +PR       PP +R   S  P+    P  ST
Sbjct: 669 STREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 15/103 (14%)

Query: 439 EAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQAR 498
           EA++PQ  +   PSP        P AP  T + PPP+ R    ++P   + P P  +  R
Sbjct: 672 EARSPQPNKRHSPSP-------RPRAP-QTSSSPPPVRRGA-SSSPQRRQSPSPSTRPIR 722

Query: 499 FIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS-TVGGQQPPS 540
            +        P P  I+ A S  P+   R   S +V G   P+
Sbjct: 723 RVS-----RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 48/161 (29%), Positives = 60/161 (37%), Gaps = 25/161 (15%)

Query: 402 WEAEQG-----------TQASNGDASTLGEETKSASNVPSGKSTD-EEEEAQTPQAPRTL 449
           W A QG           T+       ++    K++ N+PS       E  +  P      
Sbjct: 818 WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVP 877

Query: 450 GPSPPAPSSTPTPTAPIATLNQPPPL-----LRPTLPAAPALHRQPPPLQQQARF--IQP 502
            P PP P  T  PT P   + QPPPL     L P  P  P     PPP    A    + P
Sbjct: 878 PPPPPLPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936

Query: 503 RPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543
            P    PPPP + P  ++P    P P L   G   PP L G
Sbjct: 937 LPGAGIPPPPPL-PGAAIP----PPPPLPGAGIPLPPPLPG 972



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 39/101 (38%), Positives = 43/101 (42%), Gaps = 14/101 (13%)

Query: 451  PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 506
            P PP P +   P P  P A +  PPPL    +P  P L R   PPP       I P P L
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168

Query: 507  N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543
                  PPPPL  P   +P    P P L  VG   PP L G
Sbjct: 1169 PGAGIPPPPPL--PGVGIP----PPPPLPGVGIPPPPPLPG 1203



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 38/102 (37%), Positives = 43/102 (42%), Gaps = 14/102 (13%)

Query: 451  PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 506
            P PP P +   P P  P A +  PPPL R  +P  P L     PPP       I P P L
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179

Query: 507  N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGI 544
                  PPPPL  P   +P    P P L   G   PP L G+
Sbjct: 1180 PGVGIPPPPPL--PGVGIP----PPPPLPGAGIPPPPPLPGM 1215



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 38/108 (35%), Positives = 43/108 (39%), Gaps = 17/108 (15%)

Query: 451  PSPPAPSST--PTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 506
            P PP P +   P P  P A +  PPPL    +P  P L     PPP       I P P L
Sbjct: 944  PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003

Query: 507  N----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 543
                  PPPPL  P   +PP        + P P L   G   PP L G
Sbjct: 1004 PGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 39/114 (34%), Positives = 43/114 (37%), Gaps = 15/114 (13%)

Query: 443  PQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFI 500
            P A   L P  P     P P  P A +  PPPL    +P  P L     PPP       I
Sbjct: 960  PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019

Query: 501  QPRPTLN----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 543
             P P L      PPPPL  P   +PP        + P P L   G   PP L G
Sbjct: 1020 PPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 37/101 (36%), Positives = 41/101 (40%), Gaps = 14/101 (13%)

Query: 451  PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 506
            P PP P +   P P  P A +  PPPL    +P  P L     PPP       I P P L
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102

Query: 507  N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543
                  PPPPL  P   +P    P P L   G   PP L G
Sbjct: 1103 PGVGIPPPPPL--PGAGIP----PPPPLPGAGIPPPPPLPG 1137



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/110 (35%), Positives = 42/110 (38%), Gaps = 19/110 (17%)

Query: 451  PSPPAPSS-----TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPR 503
            P PP P +      P P A I     PPPL    +P  P L     PPP       I P 
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIP---PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1132

Query: 504  PTLN----QPPPPLIRPANSMPPRL-----NPRPVLSTVGGQQPPSLIGI 544
            P L      PPPPL R     PP L      P P L   G   PP L G+
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1182



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 39/111 (35%), Positives = 43/111 (38%), Gaps = 23/111 (20%)

Query: 451  PSPPAPSS-----TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPR 503
            P PP P +      P P A I     PPPL    +P  P L     PPP       I P 
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1066

Query: 504  PTLN----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 543
            P L      PPPPL  P   +PP        + P P L  VG   PP L G
Sbjct: 1067 PPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG 1115



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 27/71 (38%), Positives = 30/71 (42%), Gaps = 7/71 (9%)

Query: 451  PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQ 508
            P PP P     P P  P A +  PPPL    +P APA     PPL      I P P L  
Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA-----PPLPPPGTGIPPPPLLPV 1240

Query: 509  PPPPLIRPANS 519
              PPL+    S
Sbjct: 1241 SGPPLLPQVGS 1251



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 38/112 (33%), Positives = 43/112 (38%), Gaps = 25/112 (22%)

Query: 443  PQAPRTLGPSPPA------PSSTPTPTAPIATLNQPPPLLR---PTLPAAPALHRQPPPL 493
            P  PR   P PP       P   P P A I     PPPL     P  P  P +   PPP 
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGVGIPPPPPLPGVGIPPPP- 1199

Query: 494  QQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVG-GQQPPSLIGI 544
                    P P    PPPP + P   +PP   P P L   G G  PP L+ +
Sbjct: 1200 --------PLPGAGIPPPPPL-PGMGIPPA--PAPPLPPPGTGIPPPPLLPV 1240



 Score = 37.7 bits (86), Expect = 0.028
 Identities = 44/135 (32%), Positives = 49/135 (36%), Gaps = 38/135 (28%)

Query: 443  PQAPRTLG------PSPPAPSS-----TPTPTA--------PIATLNQPPPLLRPTLPAA 483
            PQ P   G      P PP P +      P P A        P A +  PPPL    +P  
Sbjct: 897  PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956

Query: 484  PALHRQ----PPPLQQQARFIQPRPTLN----QPPPPLIRPANSMPP-------RLNPRP 528
            P L       PPPL      I P P L      PPPPL  P   +PP        + P P
Sbjct: 957  PPLPGAGIPLPPPLPGAG--IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPP 1012

Query: 529  VLSTVGGQQPPSLIG 543
             L   G   PP L G
Sbjct: 1013 PLPGAGIPPPPPLPG 1027



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 12/78 (15%)

Query: 405 EQGTQASNGDA--STLGEE--TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTP 460
           E+G + +  DA   + GEE   +   + P     + EEEAQ        GP  PA +S P
Sbjct: 347 EEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQ--------GPDAPAAASLP 398

Query: 461 TPTAPIATLNQPPPLLRP 478
              AP     +P PL+ P
Sbjct: 399 GSPAPSQRCFKPYPLITP 416


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 39/130 (30%), Positives = 53/130 (40%), Gaps = 10/130 (7%)

Query: 418 LGEETKSASNVPSGKSTDEEE----EAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPP 473
           +G+ T ++  +  G+ +  E+    + + P AP T    P     TP   A  A     P
Sbjct: 618 VGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAP 677

Query: 474 PLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLN-QPPPPLIRPANSMPPRLNPRPVLST 532
            L  P  P  P L   PPP   Q  F  P P     PPPP   PA ++PP     P L  
Sbjct: 678 TLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPP-----PPLPA 732

Query: 533 VGGQQPPSLI 542
             G  PP ++
Sbjct: 733 PPGVPPPPIL 742



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/135 (30%), Positives = 50/135 (37%), Gaps = 22/135 (16%)

Query: 405 EQGTQASNGDASTLGEETKSA--SNVPSGKSTDEEEEAQTPQAPRTLGPS---PPAPSST 459
           ++G Q+S  D     +E  SA  ++    K       A    AP  L P+   PP P   
Sbjct: 629 DEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFP 688

Query: 460 PTPTAPIATLNQP--------PPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPP 511
           P P  P     QP        PP   P  PA PA+   PPPL      + P P L   PP
Sbjct: 689 PLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-VPPPPILPPLPP 747

Query: 512 PLIRPANSMPPRLNP 526
                    PP L P
Sbjct: 748 --------FPPGLFP 754



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 46/189 (24%), Positives = 60/189 (31%), Gaps = 34/189 (17%)

Query: 396  EEVLQEWEAEQG-TQASNGDASTLGEETKSASNVPSGKSTDEEEE--------------A 440
            EE  +E  AE+    A   D    GEE   A   P+  S   EEE              +
Sbjct: 1146 EEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205

Query: 441  QTPQAPRTLGPSPPAPSSTP--------------TPTAPIATLNQPPPLLRPTLPAAPAL 486
               + P  +G   PA S  P              +P  P   +   PPL     P     
Sbjct: 1206 MLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLE 1265

Query: 487  HRQPPPLQQQARFIQPRPTLNQP----PPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 542
                PP+        P P    P    PPP     ++  P + P P L+       P L 
Sbjct: 1266 VEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP-LAEDHPPHTPGLC 1324

Query: 543  GIQTDSQSS 551
            G    SQS+
Sbjct: 1325 GSLAKSQST 1333



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 32/129 (24%), Positives = 44/129 (34%), Gaps = 17/129 (13%)

Query: 429  PSGKSTDEEEEAQTPQAPRTLGPSPPA------PSSTP--TPTAPIATLNQPP-----PL 475
            P+      EE   + +    L P PPA      P  +P   P   +    +PP     PL
Sbjct: 1219 PADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPL 1278

Query: 476  LRPTLPAAPALHRQPPPLQQQARF----IQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 531
              P  P  P     PPP  +        + P P     PP       S+    +   V +
Sbjct: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPA 1338

Query: 532  TVGGQQPPS 540
            T GG+ P S
Sbjct: 1339 TPGGEPPLS 1347



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 33/130 (25%), Positives = 40/130 (30%), Gaps = 19/130 (14%)

Query: 409 QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIAT 468
           +A   D++T       A   P+          QTP A        P P   PT TA    
Sbjct: 369 KAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHF------PPPPEEPTATAAFGA 422

Query: 469 LNQ--------PPPL--LRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPAN 518
            +         PPPL    P     P     PPP    +  +  RPT    P P   P  
Sbjct: 423 RDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGT 482

Query: 519 SMPPRLNPRP 528
              P L   P
Sbjct: 483 ---PTLESSP 489



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 27/114 (23%), Positives = 40/114 (35%), Gaps = 21/114 (18%)

Query: 429  PSGKSTDEEEEAQTPQA------PRTLGPSPPAPSSTPTPTAPIATLNQPP--------P 474
            P  ++TD    +  P+       P T G       S  T T P     +PP         
Sbjct: 1295 PEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLS 1354

Query: 475  LLRPTLPAAPALHRQPPPL-------QQQARFIQPRPTLNQPPPPLIRPANSMP 521
            L  P +P +P  +  P P        +   R     PT ++P  PL+ P   +P
Sbjct: 1355 LSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLP 1408



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 5/92 (5%)

Query: 428  VPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLN---QPPPLLRPTLPAAP 484
            +P+G+  +      +P    T G   P P   P P A  A L    + P  L P LPA P
Sbjct: 1407 LPTGRRDERSGPLASPVLLET-GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPA-P 1464

Query: 485  ALHRQPPPLQQQARFIQPRPTLNQPPPPLIRP 516
                 PP  ++  R  +  P++     PL+RP
Sbjct: 1465 LASCPPPMKRKPGRPRRSPPSMLSLDGPLVRP 1496


>gi|112807226 hypothetical protein LOC91748 [Homo sapiens]
          Length = 1045

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 24/155 (15%)

Query: 59  MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAK-----LDEYIAIAKEK-- 111
           + VG+ +QA IP     A    D      LVW P+  +  ++     +++ +  A     
Sbjct: 723 INVGSRFQAEIPLMRDRALAAADPHKAD-LVWQPWEDLESSREKQRQVEDLLTAACSSIF 781

Query: 112 --HGYNVEQALGMLFWHKHNIEKSLADL-------PNFTPFP-------DEWTVEDKVLF 155
              G N E AL  L   + +I ++L  L       P+  P         D+W + ++ LF
Sbjct: 782 PGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLF 841

Query: 156 EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 190
            +  + + K F  +Q+++  KT+A  V++YY++KK
Sbjct: 842 NKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKK 876



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 23/114 (20%)

Query: 347 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406
           +W   E+ L  +G+  Y KDF  +  +I  KTV Q   F+  Y+++  +           
Sbjct: 832 QWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKI--------GRN 883

Query: 407 GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQ---TPQAPRTLGPSPPAPS 457
           GT  + GD  T  E           KS  EE E     + + PR   P   +PS
Sbjct: 884 GT-LTFGDVDTSDE-----------KSAQEEVEVDIKTSQKFPRVPLPRRESPS 925


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,197,759
Number of Sequences: 37866
Number of extensions: 1575621
Number of successful extensions: 21078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 380
Number of HSP's successfully gapped in prelim test: 1233
Number of HSP's that attempted gapping in prelim test: 11375
Number of HSP's gapped (non-prelim): 6651
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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