BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|209977080 REST corepressor 3 isoform a [Homo sapiens] (553 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|209977080 REST corepressor 3 isoform a [Homo sapiens] 1133 0.0 gi|8922733 REST corepressor 3 isoform d [Homo sapiens] 1013 0.0 gi|209977084 REST corepressor 3 isoform c [Homo sapiens] 899 0.0 gi|209977082 REST corepressor 3 isoform b [Homo sapiens] 740 0.0 gi|27734799 REST corepressor 2 [Homo sapiens] 558 e-159 gi|7661892 REST corepressor 1 [Homo sapiens] 506 e-143 gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens] 124 3e-28 gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens] 124 3e-28 gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo sapi... 124 3e-28 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 115 1e-25 gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 112 9e-25 gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 99 1e-20 gi|14141170 metastasis-associated protein 2 [Homo sapiens] 65 2e-10 gi|94721313 mesoderm induction early response 1, family member 3... 65 2e-10 gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 64 3e-10 gi|210031154 zinc finger protein 541 [Homo sapiens] 64 3e-10 gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens] 63 8e-10 gi|45267839 mesoderm induction early response 1, family member 2... 62 2e-09 gi|115527080 metastasis associated protein [Homo sapiens] 57 3e-08 gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 56 1e-07 gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 56 1e-07 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 54 4e-07 gi|153792074 proline rich 12 [Homo sapiens] 54 4e-07 gi|116284392 mucin 2 precursor [Homo sapiens] 53 8e-07 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 52 1e-06 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 52 1e-06 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 52 1e-06 gi|160707881 formin 2 [Homo sapiens] 52 2e-06 gi|210032580 SET domain containing 1B [Homo sapiens] 52 2e-06 gi|112807226 hypothetical protein LOC91748 [Homo sapiens] 52 2e-06 >gi|209977080 REST corepressor 3 isoform a [Homo sapiens] Length = 553 Score = 1133 bits (2931), Expect = 0.0 Identities = 553/553 (100%), Positives = 553/553 (100%) Query: 1 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR Sbjct: 1 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60 Query: 61 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL Sbjct: 61 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120 Query: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS Sbjct: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180 Query: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE Sbjct: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240 Query: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL Sbjct: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300 Query: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV Sbjct: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360 Query: 361 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE 420 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE Sbjct: 361 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE 420 Query: 421 ETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTL 480 ETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTL Sbjct: 421 ETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTL 480 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 540 PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS Sbjct: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 540 Query: 541 LIGIQTDSQSSLH 553 LIGIQTDSQSSLH Sbjct: 541 LIGIQTDSQSSLH 553 >gi|8922733 REST corepressor 3 isoform d [Homo sapiens] Length = 495 Score = 1013 bits (2620), Expect = 0.0 Identities = 495/495 (100%), Positives = 495/495 (100%) Query: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 118 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ Sbjct: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 60 Query: 119 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 178 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI Sbjct: 61 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 120 Query: 179 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 238 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK Sbjct: 121 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 180 Query: 239 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 298 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT Sbjct: 181 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 240 Query: 299 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 358 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ Sbjct: 241 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 300 Query: 359 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 418 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL Sbjct: 301 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 360 Query: 419 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP 478 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP Sbjct: 361 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP 420 Query: 479 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 538 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP Sbjct: 421 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 480 Query: 539 PSLIGIQTDSQSSLH 553 PSLIGIQTDSQSSLH Sbjct: 481 PSLIGIQTDSQSSLH 495 >gi|209977084 REST corepressor 3 isoform c [Homo sapiens] Length = 449 Score = 899 bits (2322), Expect = 0.0 Identities = 439/439 (100%), Positives = 439/439 (100%) Query: 1 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR Sbjct: 1 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60 Query: 61 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL Sbjct: 61 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120 Query: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS Sbjct: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180 Query: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE Sbjct: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240 Query: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL Sbjct: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300 Query: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV Sbjct: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360 Query: 361 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE 420 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE Sbjct: 361 RKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGE 420 Query: 421 ETKSASNVPSGKSTDEEEE 439 ETKSASNVPSGKSTDEEEE Sbjct: 421 ETKSASNVPSGKSTDEEEE 439 >gi|209977082 REST corepressor 3 isoform b [Homo sapiens] Length = 436 Score = 740 bits (1911), Expect = 0.0 Identities = 359/364 (98%), Positives = 360/364 (98%) Query: 1 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR Sbjct: 1 MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMR 60 Query: 61 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQAL 120 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDA+LDEYIAIAKEKHGYNVEQAL Sbjct: 61 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDARLDEYIAIAKEKHGYNVEQAL 120 Query: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS Sbjct: 121 GMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIAS 180 Query: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE Sbjct: 181 LVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKE 240 Query: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL Sbjct: 241 GNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTIL 300 Query: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGV 360 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQG Sbjct: 301 RQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGT 360 Query: 361 RKYG 364 G Sbjct: 361 DPTG 364 Score = 38.1 bits (87), Expect = 0.021 Identities = 22/103 (21%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Query: 348 WTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQG 407 WT E+++L Q +GK F I ++ +KT+ + ++ ++++ + ++ + Sbjct: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLA 206 Query: 408 TQASNGDASTLGEETKSASNVPSGKSTDEE--EEAQTPQAPRT 448 + + GD+ EET S +E +E T Q +T Sbjct: 207 NRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQT 249 >gi|27734799 REST corepressor 2 [Homo sapiens] Length = 523 Score = 558 bits (1439), Expect = e-159 Identities = 311/552 (56%), Positives = 387/552 (70%), Gaps = 48/552 (8%) Query: 1 MPGMMEK---GPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDV 57 MP +MEK G +L ++R+ + NGG +SE +S + HD Sbjct: 1 MPSVMEKPSAGSGILSRSRAK---------------TVPNGGQPHSEDDSS-EEEHSHDS 44 Query: 58 GMRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNV 116 +RVG YQA IPE P + +Y++K+ GMLVWSP H + DAKLD+YIA+AKEKHGYN+ Sbjct: 45 MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNI 104 Query: 117 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDK 176 EQALGML WHKH++EKSLADL NFTPFPDEWTVEDKVLFEQAF FHGK F RIQQMLPDK Sbjct: 105 EQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDK 164 Query: 177 TIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDP-KK 235 I SLVKYYYSWKKTRSRTS+MDRQAR+L R ++ DS D++EE G S+ +P Sbjct: 165 LIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR---GGVSEGEPDPA 220 Query: 236 EAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNA 295 + K+E +P+ ++ G G++E Q Q+RHH R++ RPPKGMYL+ E + AVS SP+ Sbjct: 221 DPKREPLPSRPL-NARPGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDL 279 Query: 296 ANTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLL 355 AN LR LD +LISLKRQVQ+ KQ NS+L+Q +EGGI+ +PPE+N K N+RWTT+EQLL Sbjct: 280 ANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLL 339 Query: 356 AVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDA 415 AVQ +R+YGKDF AIA+VIGNKT+ QVK FFV+YRRRFNLEEVLQEWEAEQ A Sbjct: 340 AVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPG---A 396 Query: 416 STLGEETKSASNVPSGKSTDEEEEAQ----TPQAPRTLGPSPPAPSSTPTPTAPIATLNQ 471 EE + + +P+ + +E++E Q + PR++ P+PP P P PT +L+Q Sbjct: 397 PVPMEEARRGAPLPA-PALEEDDEVQITSVSTSVPRSVPPAPPPP---PPPT----SLSQ 448 Query: 472 PPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 531 PPPLLRP LP AP L RQPPPL QQ RF+QPR NQPPPPLIRPA + PR + RP Sbjct: 449 PPPLLRPPLPTAPTLLRQPPPL-QQGRFLQPRLAPNQPPPPLIRPALA-APRHSARP--- 503 Query: 532 TVGGQQPPSLIG 543 G Q PP+LIG Sbjct: 504 --GPQPPPTLIG 513 >gi|7661892 REST corepressor 1 [Homo sapiens] Length = 482 Score = 506 bits (1302), Expect = e-143 Identities = 266/425 (62%), Positives = 327/425 (76%), Gaps = 20/425 (4%) Query: 19 NGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVG-MRVGAEYQARIPEFDPG-- 75 NG KS A +G SS+N + E SG SSD+EH G MRVG +YQA +P+FDP Sbjct: 64 NGQNKSLAAAAPNGNSSSNS---WEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKL 120 Query: 76 ATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQALGMLFWHKHNIEKSLA 135 A + ++DN GMLVWSP ++ +AKLDEYIAIAKEKHGYN+EQALGMLFWHKHNIEKSLA Sbjct: 121 ARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLA 180 Query: 136 DLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRT 195 DLPNFTPFPDEWTVEDKVLFEQAFSFHGK+FHRIQQMLPDK+IASLVK+YYSWKKTR++T Sbjct: 181 DLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKT 240 Query: 196 SLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLG 255 S+MDR ARK + + +S+D++EE + + D + D KE+KKE + V K Sbjct: 241 SVMDRHARK--QKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVK---- 294 Query: 256 RREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQ 315 +E S Q ++ R+K +PPKGM+L+QEDV AVS + AA T+LRQLDMEL+S+KRQ+Q Sbjct: 295 -KEKHSTQAKN---RAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQ 350 Query: 316 NAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIG 375 N KQ NSALK+K++GGIE ++ PE QK NARWTTEEQLLAVQ +RKYG+DFQAI+DVIG Sbjct: 351 NIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIG 410 Query: 376 NKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKSTD 435 NK+V QVKNFFVNYRRRFN++EVLQEWEAE G + +NG ++ + KS N S K + Sbjct: 411 NKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQ--KPVKSPDN--SIKMPE 466 Query: 436 EEEEA 440 EE+EA Sbjct: 467 EEDEA 471 >gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens] Length = 266 Score = 124 bits (310), Expect = 3e-28 Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%) Query: 59 MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 117 +RVG YQA IPE P + +Y++K G+LVWSP H + DAKLD+YI +A EKHGYN+E Sbjct: 2 VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61 Query: 118 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 177 Q LG+ + + L LP W IQQ LPDK Sbjct: 62 QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94 Query: 178 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 236 I+SLVKY+YSWKKT SRTS+ DRQAR+L ++ DSD+ E + + D PK+E Sbjct: 95 ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154 Score = 72.8 bits (177), Expect = 8e-13 Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%) Query: 366 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 425 DF AIA+VIGNKT+ QVK FFV+Y FNLEEVLQEWEAEQ + G + E + A Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226 Query: 426 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 464 + + +E+ E Q ++ S PP + P PT+ Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264 >gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens] Length = 266 Score = 124 bits (310), Expect = 3e-28 Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%) Query: 59 MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 117 +RVG YQA IPE P + +Y++K G+LVWSP H + DAKLD+YI +A EKHGYN+E Sbjct: 2 VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61 Query: 118 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 177 Q LG+ + + L LP W IQQ LPDK Sbjct: 62 QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94 Query: 178 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 236 I+SLVKY+YSWKKT SRTS+ DRQAR+L ++ DSD+ E + + D PK+E Sbjct: 95 ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154 Score = 72.8 bits (177), Expect = 8e-13 Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%) Query: 366 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 425 DF AIA+VIGNKT+ QVK FFV+Y FNLEEVLQEWEAEQ + G + E + A Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226 Query: 426 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 464 + + +E+ E Q ++ S PP + P PT+ Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264 >gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo sapiens] Length = 266 Score = 124 bits (310), Expect = 3e-28 Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%) Query: 59 MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 117 +RVG YQA IPE P + +Y++K G+LVWSP H + DAKLD+YI +A EKHGYN+E Sbjct: 2 VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61 Query: 118 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 177 Q LG+ + + L LP W IQQ LPDK Sbjct: 62 QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94 Query: 178 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 236 I+SLVKY+YSWKKT SRTS+ DRQAR+L ++ DSD+ E + + D PK+E Sbjct: 95 ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154 Score = 72.8 bits (177), Expect = 8e-13 Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%) Query: 366 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 425 DF AIA+VIGNKT+ QVK FFV+Y FNLEEVLQEWEAEQ + G + E + A Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226 Query: 426 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 464 + + +E+ E Q ++ S PP + P PT+ Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 115 bits (287), Expect = 1e-25 Identities = 107/410 (26%), Positives = 167/410 (40%), Gaps = 39/410 (9%) Query: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 203 W+ ++K F + F H K+F I L KT+A V YYY KK + SL+ R R Sbjct: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491 Query: 204 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSLQ 263 K + Q ++ PM + + +KE +KE E+ + E ++ Sbjct: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEE---------KPEVEN-- 540 Query: 264 HRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNSA 323 + + K G +++ VA S AN+ R+ + R + N A Sbjct: 541 DKEDLLKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANSEEA 595 Query: 324 LKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVK 383 + + + + ES+ RWT EE A +G+ ++G+++ AIA ++G+KTV Q K Sbjct: 596 ITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCK 650 Query: 384 NFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------PSGK 432 NF+ NY++R NL+E+LQ+ E E+ + A E + V SG Sbjct: 651 NFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGV 710 Query: 433 STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP 492 S +EEE + +A + S T A N P P P PPP Sbjct: 711 SGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPP 770 Query: 493 LQQQARFIQPRP---TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539 A +P P P PP P+ S PP + P+ PP Sbjct: 771 EDIPAP-TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPP 819 Score = 42.4 bits (98), Expect = 0.001 Identities = 89/439 (20%), Positives = 152/439 (34%), Gaps = 108/439 (24%) Query: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLA 206 WT E+ ++ HG+++ I +M+ KT++ +Y+++KK ++ ++ + K+ Sbjct: 615 WTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKME 674 Query: 207 NRHN--------------------------------QGDSDDDVEETHPMDGNDSDYD-- 232 N G+ ++ VEE N SD + Sbjct: 675 KERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESI 734 Query: 233 --PKKEAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVS 290 P EA K+ P + +G PP G + + Sbjct: 735 PSPHTEAAKDTGQNGPKPPATLGADG------------------PPPGPPTPPPEDIPAP 776 Query: 291 CSPNAANTILRQLDMELISLKRQV------QNAKQVNSALKQKMEGGIEEFKPPESNQKI 344 P A+ + K+ +A +E G EE KPP + + Sbjct: 777 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG-EEQKPPAAEELA 835 Query: 345 NARWTTEEQLL------AVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEV 398 EE + A +G K GKD +A E Sbjct: 836 VDTGKAEEPVKSECTEEAEEGPAK-GKDAEAA---------------------EATAEGA 873 Query: 399 LQEWEAEQGT-QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPS 457 L+ + E G+ +A+ +S +++ S++ S DE +EA+ R L P P Sbjct: 874 LKAEKKEGGSGRATTAKSSGAPQDSDSSATC----SADEVDEAEGGDKNRLLSPRP---- 925 Query: 458 STPTPTA-PIATLNQPPPL----LRPTLPAAPALH--RQPPPLQQQARFIQPRPTLNQPP 510 S TPT P A + PL L+ A P + + P ++ A +P P PP Sbjct: 926 SLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPA-PPP 984 Query: 511 PPLIRPANSMP--PRLNPR 527 P ++P + P P +PR Sbjct: 985 PQNLQPESDAPQQPGSSPR 1003 Score = 38.1 bits (87), Expect = 0.021 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 6/118 (5%) Query: 406 QGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPSSTP 460 Q Q + G + S P+ + E E+ A +A + G P S P Sbjct: 986 QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLP 1045 Query: 461 TPTAPIATLNQPPPLLRPT-LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPA 517 P P + P P+ AP H P L AR + PRP PPPLI A Sbjct: 1046 FPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1103 >gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens] Length = 2524 Score = 112 bits (280), Expect = 9e-25 Identities = 105/410 (25%), Positives = 167/410 (40%), Gaps = 49/410 (11%) Query: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 203 W+ ++K F + F H K+F I L KT+A V YYY KK + SL+ R R Sbjct: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491 Query: 204 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSLQ 263 K + Q ++ PM + + +KE +KE E+ + E ++ Sbjct: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEE---------KPEVEN-- 540 Query: 264 HRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNSA 323 + + K G +++ VA S AN+ R+ + R + N A Sbjct: 541 DKEDLLKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANSEEA 595 Query: 324 LKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVK 383 + + + + ES+ RWT EE A +G+ ++G+++ AIA ++G+KTV Q K Sbjct: 596 ITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCK 650 Query: 384 NFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------PSGK 432 NF+ NY++R NL+E+LQ+ E E+ + A E + V SG Sbjct: 651 NFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGV 710 Query: 433 STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP 492 S +EEE + +A G P + T ++ + P P AA + P Sbjct: 711 SGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIP--SPHTEAAKDTGQNGP- 767 Query: 493 LQQQARFIQPRPTL---NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539 +P TL PP P P +P P P G PP Sbjct: 768 --------KPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP 809 Score = 38.1 bits (87), Expect = 0.021 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 6/118 (5%) Query: 406 QGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPSSTP 460 Q Q + G + S P+ + E E+ A +A + G P S P Sbjct: 1002 QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLP 1061 Query: 461 TPTAPIATLNQPPPLLRPT-LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPA 517 P P + P P+ AP H P L AR + PRP PPPLI A Sbjct: 1062 FPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1119 Score = 32.7 bits (73), Expect = 0.89 Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 13/138 (9%) Query: 401 EWEAEQGTQASNGDASTLGEETKSASNVPSGK------STDEEEEAQTPQAPRTLGPSPP 454 E AE +A + + T +S P S DE +EA+ R L P P Sbjct: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPS 943 Query: 455 APSSTPTPTAPIATLNQPPPLLRPTLPAA---PALHRQPPPLQQQARFIQPRPTLNQPPP 511 + T P A A+ +P L + AA P + + P ++ A +P P PPP Sbjct: 944 LLTPTGDPRAN-ASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA-PPPP 1001 Query: 512 PLIRPANSMP--PRLNPR 527 ++P + P P +PR Sbjct: 1002 QNLQPESDAPQQPGSSPR 1019 Score = 31.6 bits (70), Expect = 2.0 Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 12/83 (14%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLL----- 476 T A P G T E+ P P + AP+ P P +P A PPP++ Sbjct: 772 TLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA----PPPVVPKEEK 827 Query: 477 RPTLPAAPAL---HRQPPPLQQQ 496 AAP + Q PP ++ Sbjct: 828 EEETAAAPPVEEGEEQKPPAAEE 850 >gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] Length = 2440 Score = 99.0 bits (245), Expect = 1e-20 Identities = 87/353 (24%), Positives = 151/353 (42%), Gaps = 31/353 (8%) Query: 143 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQA 202 F + WT +K +F+ F H K+F I L K++ V YYY KK + +L+ R Sbjct: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495 Query: 203 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 262 K R+ Q E+ + + ++ KKE +K+ E+ + Sbjct: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEK-------------- 541 Query: 263 QHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNS 322 + + + K + T+E A AN+ R+ S+ + A + Sbjct: 542 EDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAA 601 Query: 323 ALKQKMEGGIEEFKPPESNQKIN-ARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQ 381 A ++ + P S + + +RWT EE +A +G+ ++G+++ AIA ++G K+ Q Sbjct: 602 AATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQ 661 Query: 382 VKNFFVNYRRRFNLEEVLQEWE--------AEQGTQASNGDASTLG---EETKSASNVPS 430 KNF+ NY+RR NL+ +LQ+ + E+ AST+ +E ASN Sbjct: 662 CKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEE 721 Query: 431 GKSTDEEEEAQ----TPQAPRTLGPSPPAPSSTP-TPTAPIATLNQPPPLLRP 478 E E + +P+ + G + PA P T TAP + + P +P Sbjct: 722 NPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKP 774 >gi|14141170 metastasis-associated protein 2 [Homo sapiens] Length = 668 Score = 64.7 bits (156), Expect = 2e-10 Identities = 44/167 (26%), Positives = 81/167 (48%), Gaps = 34/167 (20%) Query: 59 MRVGAEYQARIPE-FDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKE------- 110 +RVG +YQA IP+ G + ++ M VW P + + D ++D+++ +A+ Sbjct: 147 IRVGCKYQAEIPDRLVEGESDNRNQQKMEMKVWDPDNPLTDRQIDQFLVVARAVGTFARA 206 Query: 111 -------------------KHGYNVEQALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145 + A+ L + +++ K+++ L P P + Sbjct: 207 LDCSSSIRQPSLHMSAAAASRDITLFHAMDTLQRNGYDLAKAMSTLVPQGGPVLCRDEME 266 Query: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191 EW+ + +LFE+A +GK F+ I+Q LP K++AS+V++YY WK T Sbjct: 267 EWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTT 313 Score = 29.6 bits (65), Expect = 7.5 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 3/61 (4%) Query: 348 WTTEEQLLAVQGVRKYGKDFQAI-ADVIGNKTVGQVKNFFVNYRR--RFNLEEVLQEWEA 404 W+ E +L + + KYGKDF I D + K++ + F+ ++ R+ ++ L+ EA Sbjct: 268 WSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEA 327 Query: 405 E 405 + Sbjct: 328 D 328 >gi|94721313 mesoderm induction early response 1, family member 3 [Homo sapiens] Length = 549 Score = 64.7 bits (156), Expect = 2e-10 Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 33/210 (15%) Query: 44 EPESGCSSDDEHDVGMRVGAEYQARIP----EFDPGATKYTDKDNGGMLVWSPYHSIPDA 99 E +SG S +D M +G +YQA IP E+D Y ++D L+W P + ++ Sbjct: 162 ETDSGNSPEDLRKEIM-IGLQYQAEIPPYLGEYDGNEKVYENEDQ---LLWCP-DVVLES 216 Query: 100 KLDEYIA--------------IAKEKHGYNVEQALGMLFWHKHNIEKSLADL---PNFTP 142 K+ EY+ I+ H + EQAL L HNI++++ + Sbjct: 217 KVKEYLVETSLRTGSEKIMDRISAGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQ 276 Query: 143 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKTRSRTSLMDRQ 201 WT E+ FE A GK FH IQ+ + +T+A V +YY WKK+ R +Q Sbjct: 277 GMTAWTEEECRSFEHALMLFGKDFHLIQKNKVRTRTVAECVAFYYMWKKS-ERYDYFAQQ 335 Query: 202 ARKLANRHNQGDSDDD-----VEETHPMDG 226 R R+N D V+ET + G Sbjct: 336 TRFGKKRYNHHPGVTDYMDRLVDETEALGG 365 >gi|15812226 transcriptional regulating factor 1 [Homo sapiens] Length = 1200 Score = 64.3 bits (155), Expect = 3e-10 Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 28/210 (13%) Query: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYI--------AIAKE 110 + +G +QA IPE + D LVW P+ + + L + + + A Sbjct: 781 INIGLRFQAEIPELQDISALAQDTHKA-TLVWKPWPELENHDLQQRVENLLNLCCSSALP 839 Query: 111 KHGYNVEQALGMLFWHKHNIEKSLADLPNFTPF--------------PDEWTVEDKVLFE 156 G N E AL LF K ++ +L L P D+WT ++ LF Sbjct: 840 GGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFN 899 Query: 157 QAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDD 216 +A + + K F +Q+M+ KT+A V+YYY+WKK L + +LA + + + Sbjct: 900 KALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKI---MRLGRKHRTRLAEIIDDCVTSE 956 Query: 217 DVEETHPMDGNDSDYDPKKEAKKEGNTEQP 246 + EE + D + D +++ KE +E P Sbjct: 957 EEEELEEEEEEDPEED--RKSTKEEESEVP 984 Score = 52.4 bits (124), Expect = 1e-06 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 5/152 (3%) Query: 347 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406 +WT+ E+ L + + Y KDF + ++ +KTV Q ++ +++ L + AE Sbjct: 889 KWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI 948 Query: 407 GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPI 466 + EE + KST +EEE++ P++P PP P PT P+ Sbjct: 949 IDDCVTSEEEEELEEEEEEDPEEDRKST-KEEESEVPKSPE----PPPVPVLAPTEGPPL 1003 Query: 467 ATLNQPPPLLRPTLPAAPALHRQPPPLQQQAR 498 L QP +P A+ L AR Sbjct: 1004 QALGQPSGSFICEMPNCGAVFSSRQALNGHAR 1035 Score = 31.2 bits (69), Expect = 2.6 Identities = 32/137 (23%), Positives = 45/137 (32%), Gaps = 40/137 (29%) Query: 435 DEEEEAQTPQAPRTLGPSPPAPSSTPTP------TAPIATLNQPPPLLRP---------T 479 +E E+ PQ L P PP P P T + ++ P LL P + Sbjct: 546 EEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNS 605 Query: 480 LPAAPALHRQP----------------------PPLQQQARFIQPRPTLNQPPPPLIRPA 517 AAP+ +P P ++ + +Q + P PL P Sbjct: 606 TVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPP 665 Query: 518 NSMPPRLNPRPVLSTVG 534 PP NP P S G Sbjct: 666 ---PPSYNPNPAASYSG 679 >gi|210031154 zinc finger protein 541 [Homo sapiens] Length = 1365 Score = 64.3 bits (155), Expect = 3e-10 Identities = 48/155 (30%), Positives = 72/155 (46%), Gaps = 24/155 (15%) Query: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPY-----HSIPDAKLDEYIAIAKEK-- 111 + +G+ +QA IPE + TD ++ LVW P+ S ++ E +A Sbjct: 1074 INIGSRFQAEIPELQERSLAGTD-EHVASLVWKPWGDMMISSETQDRVTELCNVACSSVM 1132 Query: 112 --HGYNVEQALGMLFWHKHNIEKSLADLPNFTPFP--------------DEWTVEDKVLF 155 G N+E AL L + N++ +L L P D WT +K LF Sbjct: 1133 PGGGTNLELALHCLHEAQGNVQVALETLLLRGPHKPRTHLLADYRYTGSDVWTPIEKRLF 1192 Query: 156 EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 190 ++AF H K F+ I +M+ KT+A V+YYY WKK Sbjct: 1193 KKAFYAHKKDFYLIHKMIQTKTVAQCVEYYYIWKK 1227 >gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens] Length = 515 Score = 62.8 bits (151), Expect = 8e-10 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 34/167 (20%) Query: 59 MRVGAEYQARIPEFD-PGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 114 +RVG YQA IPE G + ++ + VW P + D ++D+++ +A+ + Sbjct: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209 Query: 115 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145 +V Q A+ L+ H +++ +++ L P P + Sbjct: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269 Query: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191 EW+ + LFE+A +GK F+ I+Q LP K++ S+++YYY WK T Sbjct: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316 >gi|45267839 mesoderm induction early response 1, family member 2 [Homo sapiens] Length = 545 Score = 61.6 bits (148), Expect = 2e-09 Identities = 59/214 (27%), Positives = 93/214 (43%), Gaps = 32/214 (14%) Query: 44 EPESGCSSDDEHDV--------GMRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHS 95 EP S SSD E D + VG ++QA + +N L+W P Sbjct: 174 EPGSSASSDTEEDSLPANKCKKEIMVGPQFQADLSNLHLNRHCEKIYENEDQLLWDP-SV 232 Query: 96 IPDAKLDEYIAIAKEKHGYNV--------------EQALGMLFWHKHNIEKSLADLP-NF 140 +P+ +++E++ A ++ + + EQAL L N+E++L L N Sbjct: 233 LPEREVEEFLYRAVKRRWHEMAGPQLPEGEAVKDSEQALYELVKCNFNVEEALRRLRFNV 292 Query: 141 TPFPD---EWTVEDKVLFEQAFSFHGKSFHRIQ-QMLPDKTIASLVKYYYSWKKTRSRTS 196 D W+ E+ FE F HGK+FH IQ + +++ V+YYY WKK+ R Sbjct: 293 KVIRDGLCAWSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKS-ERYD 351 Query: 197 LMDRQARKLANRHNQGDSDDDVEETHPMDGNDSD 230 +Q R L R D ++ +DG+D D Sbjct: 352 YFAQQTR-LGRRKYVPSGTTDADQ--DLDGSDPD 382 Score = 40.4 bits (93), Expect = 0.004 Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 22/183 (12%) Query: 348 WTTEEQLLAVQGVRKYGKDFQAI-ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406 W+ EE G R +GK+F I A+ + ++VG+ ++ +++ + Q+ Sbjct: 302 WSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQ----- 356 Query: 407 GTQASNGDASTLGEETKSASNVPSGKS-TDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAP 465 + LG VPSG + D++ + P P P P + T T P Sbjct: 357 ---------TRLGRR----KYVPSGTTDADQDLDGSDPDGPGR--PRPEQDTLTGMRTDP 401 Query: 466 IATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLN 525 ++ L P + + +P P Q P L+ PP L PA+ P Sbjct: 402 LSVDGTAGGLDEPGVASDGLPSSEPGPCSFQQLDESPAVPLSHRPPALADPASYQPAVTA 461 Query: 526 PRP 528 P P Sbjct: 462 PEP 464 >gi|115527080 metastasis associated protein [Homo sapiens] Length = 715 Score = 57.4 bits (137), Expect = 3e-08 Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 34/167 (20%) Query: 59 MRVGAEYQARIPEF-DPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 114 +RVG YQA I + G D+ VW ++ + D ++D+++ +A+ + Sbjct: 167 IRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARA 226 Query: 115 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 145 +V Q A+ L + ++I K+++ L P P + Sbjct: 227 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEME 286 Query: 146 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 191 EW+ + LFE+A +GK F IQQ LP K++ S+++YYY WK T Sbjct: 287 EWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTT 333 >gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2 [Homo sapiens] Length = 1481 Score = 55.8 bits (133), Expect = 1e-07 Identities = 64/247 (25%), Positives = 97/247 (39%), Gaps = 42/247 (17%) Query: 308 ISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVR--KYGK 365 +S K++ + A + + K G F P + N + A+ + E + V+ K Sbjct: 399 LSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAP 458 Query: 366 DFQAI------ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG 419 D + + +V + G+VK N E+ L + QGT+ S A L Sbjct: 459 DTELVNVTHLNTEVKNSSDTGKVK-------LDENSEKHLVKDLKAQGTRDSKPIA--LK 509 Query: 420 EETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPT 479 EE + + K T+ E+ P P P PP P++TP P Q PPL P Sbjct: 510 EE------IVTPKETETSEKETPPPLPTIASPPPPLPTTTPPP--------QTPPL--PP 553 Query: 480 LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539 LP PAL +QPP Q F Q + PP S +S+ QPP Sbjct: 554 LPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTS---------AVSSQANSQPP 604 Query: 540 SLIGIQT 546 + ++T Sbjct: 605 VQVSVKT 611 Score = 35.4 bits (80), Expect = 0.14 Identities = 39/161 (24%), Positives = 56/161 (34%), Gaps = 21/161 (13%) Query: 379 VGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG--EETKSASN----VPSGK 432 + Q+ N N + LE + Q A + D+ T+ E K A + +PS + Sbjct: 1134 MAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAE 1193 Query: 433 STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPP------PLLRPTLPAAPAL 486 T E + L T P + N P PT+P A Sbjct: 1194 QTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAA 1253 Query: 487 HRQPPPLQQQARFIQPRPTLNQPPPPLIR-PANSMPPRLNP 526 ++PP P P PPPPL+ +S P LNP Sbjct: 1254 EKRPPE--------PPGPPPPPPPPPLVEGDLSSAPQELNP 1286 >gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1 [Homo sapiens] Length = 1490 Score = 55.8 bits (133), Expect = 1e-07 Identities = 64/247 (25%), Positives = 97/247 (39%), Gaps = 42/247 (17%) Query: 308 ISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVR--KYGK 365 +S K++ + A + + K G F P + N + A+ + E + V+ K Sbjct: 399 LSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAP 458 Query: 366 DFQAI------ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG 419 D + + +V + G+VK N E+ L + QGT+ S A L Sbjct: 459 DTELVNVTHLNTEVKNSSDTGKVK-------LDENSEKHLVKDLKAQGTRDSKPIA--LK 509 Query: 420 EETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPT 479 EE + + K T+ E+ P P P PP P++TP P Q PPL P Sbjct: 510 EE------IVTPKETETSEKETPPPLPTIASPPPPLPTTTPPP--------QTPPL--PP 553 Query: 480 LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539 LP PAL +QPP Q F Q + PP S +S+ QPP Sbjct: 554 LPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTS---------AVSSQANSQPP 604 Query: 540 SLIGIQT 546 + ++T Sbjct: 605 VQVSVKT 611 Score = 30.8 bits (68), Expect = 3.4 Identities = 26/78 (33%), Positives = 28/78 (35%), Gaps = 24/78 (30%) Query: 453 PPAPSSTPTPTAPIATLNQP---PPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQP 509 P P TPT A P PP RP P P PPP P Sbjct: 1238 PQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGP-----PPP---------------PP 1277 Query: 510 PPPLIR-PANSMPPRLNP 526 PPPL+ +S P LNP Sbjct: 1278 PPPLVEGDLSSAPQELNP 1295 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 53.9 bits (128), Expect = 4e-07 Identities = 51/167 (30%), Positives = 70/167 (41%), Gaps = 34/167 (20%) Query: 403 EAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPS 457 E+E +++S+ D+ E S ++++ Q QAP + PP P Sbjct: 702 ESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPP 761 Query: 458 STPTPTAPIATLNQ-PPPLLRPTLP--AAPALHRQPPP--------LQQQ---------A 497 P P P Q PPP P++P AAPA+ PPP L+ Q Sbjct: 762 QQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIG 821 Query: 498 RFIQPRPTLNQP--PPPLIR-PANSMPPRLNPRPVLSTVGGQQPPSL 541 F QP L QP PP L + P +S PP LN V+S PP+L Sbjct: 822 HFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVS------PPAL 862 Score = 43.9 bits (102), Expect = 4e-04 Identities = 34/109 (31%), Positives = 40/109 (36%), Gaps = 19/109 (17%) Query: 438 EEAQTPQAPRTLGPS-------PPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP 490 ++ Q Q P L PS PP P P+ QPPP P P QP Sbjct: 933 QQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQP 992 Query: 491 PPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539 PP + +Q + QPPP P PP P GQQPP Sbjct: 993 PPRPVHLQPMQFSTHIQQPPP----PQGQQPPHPPP--------GQQPP 1029 Score = 40.4 bits (93), Expect = 0.004 Identities = 42/159 (26%), Positives = 61/159 (38%), Gaps = 26/159 (16%) Query: 405 EQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTL--GPSPPAPSST--- 459 +Q ++ SN A+ + + + P+ T + Q P+ L PPAP T Sbjct: 868 QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927 Query: 460 -------------PTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTL 506 PTP P + PP P LP P P +QQQ + P P Sbjct: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPP---PPLPPPPH-----PSVQQQLQQQPPPPPP 979 Query: 507 NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGIQ 545 QP PP + P ++ +P+ + QQPP G Q Sbjct: 980 PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQ 1018 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 1/85 (1%) Query: 443 PQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQP 502 P + L PP P P P P +QPPP P + H Q PP Q + P Sbjct: 964 PSVQQQLQQQPPPPPP-PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHP 1022 Query: 503 RPTLNQPPPPLIRPANSMPPRLNPR 527 P PPP +P + +PR Sbjct: 1023 PPGQQPPPPQPAKPQQVIQHHHSPR 1047 Score = 38.9 bits (89), Expect = 0.012 Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 30/149 (20%) Query: 419 GEETKSASNVPSGKST-DEEEEAQTPQAPRTLGPSPPAPSSTPTP----------TAPIA 467 G K G ST +A TP +T P+PP +TP P P+ Sbjct: 180 GRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVM 239 Query: 468 TLNQPPPLLRPTLPAAPALHRQPP-----PLQQQARFIQPRP-----------TLNQPPP 511 T+ P PL P P P + PP P+Q I P + P Sbjct: 240 TVVPPQPLQTP--PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297 Query: 512 PLIRPANSMPPRLNPRPVLSTVGGQQPPS 540 I P + PP L P P + +G ++ S Sbjct: 298 TTIDPIHE-PPSLPPEPKTTKLGQRRESS 325 Score = 35.4 bits (80), Expect = 0.14 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 18/96 (18%) Query: 451 PSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALH----RQPPPLQQQARFIQPRPTL 506 P P P P P + PP L + + + PALH +QP +A + P+P Sbjct: 831 PQPELPPHLPQPPEH----STPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA- 885 Query: 507 NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 542 PP + PA + P L P+P ++ QPP ++ Sbjct: 886 ---RPPAVSPALTQTPLL-PQPPMA-----QPPQVL 912 Score = 30.8 bits (68), Expect = 3.4 Identities = 27/109 (24%), Positives = 37/109 (33%), Gaps = 2/109 (1%) Query: 436 EEEEAQTPQAP-RTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQ 494 EE E QA R G + T P T PP + P P + P P Sbjct: 167 EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP 226 Query: 495 QQAR-FIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 542 I P + PP ++ +PP+ P P + Q P +I Sbjct: 227 AVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPII 275 Score = 30.4 bits (67), Expect = 4.4 Identities = 32/118 (27%), Positives = 39/118 (33%), Gaps = 40/118 (33%) Query: 453 PPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP----------------PPLQ-- 494 P PS A + PP + P L P L + P PPL Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSM 926 Query: 495 ------QQARFIQPRPTL-------NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539 QQ + +QP L +QPPPPL P P P + QQPP Sbjct: 927 QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPP---------PHPSVQQQLQQQPP 975 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 53.9 bits (128), Expect = 4e-07 Identities = 53/170 (31%), Positives = 69/170 (40%), Gaps = 30/170 (17%) Query: 393 FNLEEVLQEWEAEQGTQASNGDASTLGEETK-SASNVPSGKSTDEEEEAQTPQAPRTLGP 451 F L L+ E+E L EE K + +PS S +E+ A+ ++ Sbjct: 1341 FGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400 Query: 452 S----------PPAPSSTPT--PTAPIATLNQPPPLLRPTLPAA--------PALHRQPP 491 + P +STP P AP A + PPPL P LP+A P L +PP Sbjct: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPL--PGLPSANSNGTPEPPLLEEKPP 1458 Query: 492 PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSL 541 P A QP+P PPPP +PA PP L V T PP L Sbjct: 1459 PTPPPAPTPQPQP---PPPPPPPQPALPSPPPL----VAPTPSSPPPPPL 1501 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/86 (37%), Positives = 37/86 (43%), Gaps = 12/86 (13%) Query: 436 EEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495 EE+ TP T P PP P P P P PPPL+ PT P++P PPPL Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPALP-----SPPPLVAPT-PSSPP----PPPLPP 1503 Query: 496 QARFIQPRPTLNQPPPPLIRPANSMP 521 P P PPPP P + P Sbjct: 1504 PPPPAMPSPP--PPPPPAAAPLAAPP 1527 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/81 (38%), Positives = 35/81 (43%), Gaps = 11/81 (13%) Query: 442 TPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQ 501 TP+ P PP P PTP QPPP P PA P+ PPPL Sbjct: 1447 TPEPPLLEEKPPPTPPPAPTPQP------QPPPPPPPPQPALPS----PPPLVAPTPSSP 1496 Query: 502 PRPTLNQPPPPLIRPANSMPP 522 P P L PPPP + P+ PP Sbjct: 1497 PPPPLPPPPPPAM-PSPPPPP 1516 Score = 45.4 bits (106), Expect = 1e-04 Identities = 40/153 (26%), Positives = 55/153 (35%), Gaps = 17/153 (11%) Query: 394 NLEEVLQEWEAEQGTQASNGDAS-TLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPS 452 NLE + E+ + A N D ++ + + P D P AP P Sbjct: 1373 NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG 1432 Query: 453 PP------APSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTL 506 PP + +S TP P+ L + PP P P PPP P+P L Sbjct: 1433 PPPLPGLPSANSNGTPEPPL--LEEKPPPTPPPAPTPQPQPPPPPP--------PPQPAL 1482 Query: 507 NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539 PPP + +S PP P P + PP Sbjct: 1483 PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP 1515 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 6/84 (7%) Query: 429 PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHR 488 P T + + P P+ PSPP P PTP++P PPPL P PA P+ Sbjct: 1461 PPPAPTPQPQPPPPPPPPQPALPSPP-PLVAPTPSSP-----PPPPLPPPPPPAMPSPPP 1514 Query: 489 QPPPLQQQARFIQPRPTLNQPPPP 512 PPP P P P Sbjct: 1515 PPPPAAAPLAAPPEEPAAPSPEDP 1538 Score = 34.3 bits (77), Expect = 0.31 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 18/112 (16%) Query: 439 EAQTPQAPRTLGPSPP---------APSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQ 489 EA P P L P PP APS P+P+A ++ P R P P Sbjct: 784 EAGGPDLPLVLPPPPPQLLPSVLSHAPS--PSPSASKVGVHLLEPATRDGAPQPPPPPPP 841 Query: 490 PP---PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 538 PP PLQ +A ++ P P +RP S+ P P + +G +P Sbjct: 842 PPPPMPLQLEAH-LRSHGLEPAAPSPRLRPEESLDP---PGAMQELLGALEP 889 Score = 32.0 bits (71), Expect = 1.5 Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 9/101 (8%) Query: 429 PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP--TAPIATLNQPPPLLRPTLPAAPAL 486 P G +A P P P PPAP+S P T+PI +P LL+ + + L Sbjct: 1026 PLGLIQSGPHQAAPPPPPPP--PPPPAPASEPKGGLTSPIFCSTKPKKLLKTS--SFHLL 1081 Query: 487 HRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPR 527 R+ PP Q + PA+ RLNPR Sbjct: 1082 RRRDPPFQTPKKLYAQEYEFEADEDKADVPADI---RLNPR 1119 Score = 30.0 bits (66), Expect = 5.8 Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 12/125 (9%) Query: 432 KSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPP 491 K+T E+ QTP+ T P PPAP P+ P+ + + R P Sbjct: 1708 KTTSEKPPEQTPE---TAMPEPPAPEK-PSLLRPVEKEKEKEKVTRGERPLRGERATSGR 1763 Query: 492 PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQ-----PPSLIGIQT 546 + + +P ++ P + PP + L GG PP G + Sbjct: 1764 QTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPP---GSSS 1820 Query: 547 DSQSS 551 DS+SS Sbjct: 1821 DSESS 1825 Score = 29.3 bits (64), Expect = 9.8 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 3/50 (6%) Query: 439 EAQTP-QAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP--TLPAAPA 485 +A+ P A + P P AP+ P P P T ++ PP P +P PA Sbjct: 1679 QAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPA 1728 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 52.8 bits (125), Expect = 8e-07 Identities = 42/151 (27%), Positives = 57/151 (37%), Gaps = 19/151 (12%) Query: 402 WEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPP-----AP 456 W ++ + +T S + +P +T T P T PSPP P Sbjct: 1390 WPMDKCITTPSPPTTTPSPPPTSTTTLPP-TTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448 Query: 457 SSTPTPTAPIATLNQPPPLLRP----TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPP- 511 T TP+ PI+T PPP P T P+ P PP P PT PP Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT----PPPTTTPSPPT 1504 Query: 512 --PLIRPAN--SMPPRLNPRPVLSTVGGQQP 538 P+ PA+ ++PP P P +T P Sbjct: 1505 TTPITPPASTTTLPPTTTPSPPTTTTTTPPP 1535 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 16/114 (14%) Query: 433 STDEEEEAQTPQAPRTLGPSPP-----APSSTPTPTAPIATLNQPPPLLRPTLPAA---- 483 ST TP P T +PP +P +T TP+ P T PPP P+ P Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611 Query: 484 --PALHRQPP---PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLST 532 P PP P+ PT PPP + PP P P +T Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP--TTTTTPPPTTTPSPPTTT 1663 Score = 43.1 bits (100), Expect = 7e-04 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 17/132 (12%) Query: 424 SASNVPSGKSTDEEEEAQTPQAPRTLGPSPPA-----PSSTPTP-----TAPIATLNQPP 473 + + P +T + T P T PSPP P++TP+P T P T P Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502 Query: 474 PLLRPTLPAAPALHRQP--PPLQQQARFIQPRPTLNQPPP---PLIRPAN--SMPPRLNP 526 P P P A P P P PT PP P+ P + ++PP P Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562 Query: 527 RPVLSTVGGQQP 538 P +T P Sbjct: 1563 SPPPTTTTTPPP 1574 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 16/109 (14%) Query: 440 AQTPQAPRTLGPSPPAPSST-PTPT---APIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495 A T P T PSPP ++T P PT +P T PP TLP P PPP Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTT 1569 Query: 496 QARFIQPRPTLNQPPPPLIRPA------NSMPPRLNPRPVLSTVGGQQP 538 P PT PP P+ + PP P P +T P Sbjct: 1570 TT----PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614 Score = 42.4 bits (98), Expect = 0.001 Identities = 34/116 (29%), Positives = 41/116 (35%), Gaps = 17/116 (14%) Query: 433 STDEEEEAQTPQAPRTLGPSPP-----APSSTPTPTAPIATLNQPPPLLRP-----TLPA 482 ST TP P T +PP +P +T TP+ PI T PPP P T P+ Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690 Query: 483 APALHRQPP-----PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTV 533 P P P P T PPP S P P P +T+ Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS--PTTTPSPPTTTM 1744 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/110 (30%), Positives = 38/110 (34%), Gaps = 12/110 (10%) Query: 429 PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHR 488 P +T T P T PSPP T T T P T PP P P P Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPP----TTTTTTPPPTTTPSPPTTTPITP--PTSTT 1633 Query: 489 QPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 538 PP + P PT PPP P S P P P ++T P Sbjct: 1634 TLPPTTTPS----PPPTTTTTPPPTTTP--SPPTTTTPSPPITTTTTPPP 1677 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 14/115 (12%) Query: 426 SNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPA 485 + P +T T P T PSPP T TP P + PP P+ P P Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPP----TTTPITPPTSTTTLPPTTTPSPP--PT 1646 Query: 486 LHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 540 PPP P P P P I + PP P ++T PP+ Sbjct: 1647 TTTTPPPT------TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT--PSPPT 1693 Score = 35.0 bits (79), Expect = 0.18 Identities = 42/180 (23%), Positives = 56/180 (31%), Gaps = 17/180 (9%) Query: 385 FFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQ 444 F +NY E + + T N T T + + P+ T + TP Sbjct: 1865 FCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1924 Query: 445 APRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPR 503 T P P+ T TP T PI T P PT P P P Sbjct: 1925 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPT 1981 Query: 504 PTLNQPP-----------PPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGIQTDSQSSL 552 PT Q P P P + P P +TV P+ G QT + + + Sbjct: 1982 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPTGTQTPTTTPI 2039 Score = 34.3 bits (77), Expect = 0.31 Identities = 32/109 (29%), Positives = 41/109 (37%), Gaps = 11/109 (10%) Query: 442 TPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP---LQQQAR 498 TP +T +P ++T TPT PP T P A PPP Q +R Sbjct: 4166 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR 4225 Query: 499 F----IQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGG---QQPPS 540 + TL PP I ++ PP P +T GG PPS Sbjct: 4226 STSSPLTESTTLLSTLPPAIEMTSTAPPS-TPTAPTTTSGGHTLSPPPS 4273 Score = 34.3 bits (77), Expect = 0.31 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 5/50 (10%) Query: 446 PRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495 P T P+P STPTP+ P +T ++P P +P P P PP Q+ Sbjct: 4377 PSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKP--PECPDF---DPPRQE 4421 Score = 33.9 bits (76), Expect = 0.40 Identities = 25/91 (27%), Positives = 32/91 (35%), Gaps = 8/91 (8%) Query: 443 PQAPRTLGPSP-PAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQ 501 P + TL P+ P+P T T T P T PP P+ P PPP + Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT--TTPPPTTTPS---- 1682 Query: 502 PRPTLNQPPPPLIRPANSMPPRLNPRPVLST 532 P P PP P P+ +T Sbjct: 1683 -SPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712 Score = 33.1 bits (74), Expect = 0.68 Identities = 32/131 (24%), Positives = 46/131 (35%), Gaps = 8/131 (6%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTP-TPTAPIATLNQPPPLLRPTL 480 T + + P+G T T +PP SSTP T + + L + LL Sbjct: 4183 TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 540 PA PP TL+ PP + PP R +T G P+ Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPP-----STTTSPPGTPTRG--TTTGSSSAPT 4295 Query: 541 LIGIQTDSQSS 551 +QT + S+ Sbjct: 4296 PSTVQTTTTSA 4306 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2017 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2076 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2077 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 2134 TTTV--TPTPTPTGTQTPTTTPI 2154 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2132 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2191 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2192 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 2249 TTTV--TPTPTPTGTQTPTTTPI 2269 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2247 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2306 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2307 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2363 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 2364 TTTV--TPTPTPTGTQTPTTTPI 2384 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2422 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 2479 TTTV--TPTPTPTGTQTPTTTPI 2499 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2536 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2537 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 2594 TTTV--TPTPTPTGTQTPTTTPI 2614 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2651 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2652 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 2709 TTTV--TPTPTPTGTQTPTTTPI 2729 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2767 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 2824 TTTV--TPTPTPTGTQTPTTTPI 2844 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2822 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2881 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2882 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 2939 TTTV--TPTPTPTGTQTPTTTPI 2959 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 2937 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2996 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 2997 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3054 TTTV--TPTPTPTGTQTPTTTPI 3074 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3111 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 3112 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3169 TTTV--TPTPTPTGTQTPTTTPI 3189 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3167 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3226 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 3227 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3284 TTTV--TPTPTPTGTQTPTTTPI 3304 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3341 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 3342 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3399 TTTV--TPTPTPTGTQTPTTTPI 3419 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3456 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 3457 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3514 TTTV--TPTPTPTGTQTPTTTPI 3534 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3512 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3571 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 3572 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3629 TTTV--TPTPTPTGTQTPTTTPI 3649 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3627 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3686 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 3687 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3744 TTTV--TPTPTPTGTQTPTTTPI 3764 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3742 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3801 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 3802 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3859 TTTV--TPTPTPTGTQTPTTTPI 3879 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3916 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 3917 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 3974 TTTV--TPTPTPTGTQTPTTTPI 3994 Score = 32.0 bits (71), Expect = 1.5 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 3972 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4031 Query: 481 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 529 P P P PT Q P P P + P P Sbjct: 4032 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4088 Query: 530 LSTVGGQQPPSLIGIQTDSQSSL 552 +TV P+ G QT + + + Sbjct: 4089 TTTV--TPTPTPTGTQTPTTTPI 4109 Score = 32.0 bits (71), Expect = 1.5 Identities = 33/142 (23%), Positives = 42/142 (29%), Gaps = 12/142 (8%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 480 T + + P+ T + TP T P P+ T TP T PI T P PT Sbjct: 4087 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4146 Query: 481 PAAP---------ALHRQPPPLQQQARFIQPRPTLN--QPPPPLIRPANSMPPRLNPRPV 529 P + P P Q P T P P P + P+ Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI 4206 Query: 530 LSTVGGQQPPSLIGIQTDSQSS 551 PP QT +S Sbjct: 4207 AELTTSNPPPESSTPQTSRSTS 4228 Score = 30.0 bits (66), Expect = 5.8 Identities = 23/73 (31%), Positives = 27/73 (36%), Gaps = 7/73 (9%) Query: 409 QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAP------RTLGPSPPAPSSTP-T 461 Q S +S L E T S +P TP AP TL P P +S P T Sbjct: 4222 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT 4281 Query: 462 PTAPIATLNQPPP 474 PT T + P Sbjct: 4282 PTRGTTTGSSSAP 4294 Score = 29.3 bits (64), Expect = 9.8 Identities = 28/100 (28%), Positives = 32/100 (32%), Gaps = 25/100 (25%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLP 481 T S + PS T TP + T P PP +TP+PT T PP TLP Sbjct: 1698 TPSPTTTPSSPITT----TTTPSSTTTPSP-PPTTMTTPSPT----TTPSPPTTTMTTLP 1748 Query: 482 AAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMP 521 P P PP I P P Sbjct: 1749 PTTT----------------SSPLTTTPLPPSITPPTFSP 1772 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 52.0 bits (123), Expect = 1e-06 Identities = 75/303 (24%), Positives = 110/303 (36%), Gaps = 65/303 (21%) Query: 276 PKGMYLTQEDVVAVSCSPNAANTIL--RQLDMELISLKRQVQNAKQVNSALKQKMEGGIE 333 P+ L +E + + N A+ R L +E+ L Q+ + +V + Sbjct: 419 PQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKS---------- 468 Query: 334 EFKPPESNQKINARWTTEEQLLAVQGVRKYGKDF-QAIADVIGNKTVGQVKNFFVNYRRR 392 E K E +K+++ T +L ++K DF Q + D+ G K + + Sbjct: 469 EAKAAELEKKLDSELTARHELQVE--MKKMESDFEQKLQDLQGEKDA--------LHSEK 518 Query: 393 FNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKST-------DEEEEAQTPQA 445 + Q+ EAE G+ + L +E + A + S A P A Sbjct: 519 QQIATEKQDLEAE--VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 576 Query: 446 PR------TLGPSPPAPSSTPTPTAPIATLNQPPPL-------LRPTLPAAPALHRQPPP 492 P T+ P PPAP + TP P PPPL P+LP A+ PPP Sbjct: 577 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI-SPPPP 635 Query: 493 LQQQARFIQPRP----------------TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQ 536 L A P P T PPPPL A PP P P+ + G Sbjct: 636 LSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP---PPPLPGSAGIP 692 Query: 537 QPP 539 PP Sbjct: 693 PPP 695 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 21/112 (18%) Query: 443 PQAPRTLGPSPPAPSSTPTPTA-------PIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495 P P G P+PSS P TA P + PPP P LP + + PPPL Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP---PPLPGSAGIPPPPPPLPG 700 Query: 496 QARFIQPRPTL----NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543 +A P P L PPPP +PP P P + G PP G Sbjct: 701 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGM----GMPPPPPFG 745 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 52.0 bits (123), Expect = 1e-06 Identities = 75/303 (24%), Positives = 110/303 (36%), Gaps = 65/303 (21%) Query: 276 PKGMYLTQEDVVAVSCSPNAANTIL--RQLDMELISLKRQVQNAKQVNSALKQKMEGGIE 333 P+ L +E + + N A+ R L +E+ L Q+ + +V + Sbjct: 428 PQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKS---------- 477 Query: 334 EFKPPESNQKINARWTTEEQLLAVQGVRKYGKDF-QAIADVIGNKTVGQVKNFFVNYRRR 392 E K E +K+++ T +L ++K DF Q + D+ G K + + Sbjct: 478 EAKAAELEKKLDSELTARHELQVE--MKKMESDFEQKLQDLQGEKDA--------LHSEK 527 Query: 393 FNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKST-------DEEEEAQTPQA 445 + Q+ EAE G+ + L +E + A + S A P A Sbjct: 528 QQIATEKQDLEAE--VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 585 Query: 446 PR------TLGPSPPAPSSTPTPTAPIATLNQPPPL-------LRPTLPAAPALHRQPPP 492 P T+ P PPAP + TP P PPPL P+LP A+ PPP Sbjct: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI-SPPPP 644 Query: 493 LQQQARFIQPRP----------------TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQ 536 L A P P T PPPPL A PP P P+ + G Sbjct: 645 LSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP---PPPLPGSAGIP 701 Query: 537 QPP 539 PP Sbjct: 702 PPP 704 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 21/112 (18%) Query: 443 PQAPRTLGPSPPAPSSTPTPTA-------PIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 495 P P G P+PSS P TA P + PPP P LP + + PPPL Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP---PPLPGSAGIPPPPPPLPG 709 Query: 496 QARFIQPRPTL----NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543 +A P P L PPPP +PP P P + G PP G Sbjct: 710 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGM----GMPPPPPFG 754 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 52.0 bits (123), Expect = 1e-06 Identities = 45/157 (28%), Positives = 65/157 (41%), Gaps = 19/157 (12%) Query: 401 EWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSS-- 458 E E + + NG+ + S S PS + +E +P+ R PSPP Sbjct: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET---SPRGRRRRSPSPPPTRRRR 559 Query: 459 TPTPTAPIATLNQPPPLLRPTLPAAPALHRQP------PPLQQQARFIQP--RPTLNQPP 510 +P+P P P P R P+ P R P PP+Q++ P R T + PP Sbjct: 560 SPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619 Query: 511 PPLIRPANSMPPRLN------PRPVLSTVGGQQPPSL 541 PP R + S PP+ P+ S V ++ PSL Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656 Score = 31.6 bits (70), Expect = 2.0 Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 11/127 (8%) Query: 422 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPP----APSS-----TPTP-TAPIATLNQ 471 ++S S + + P+AP+T PP A SS +P+P T PI +++ Sbjct: 667 SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726 Query: 472 PPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 531 P + A+P+ ++ P P +PP P P S P N P + Sbjct: 727 TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP-PSPVQSQSPSTNWSPAVP 785 Query: 532 TVGGQQP 538 + P Sbjct: 786 VKKAKSP 792 Score = 31.2 bits (69), Expect = 2.6 Identities = 26/113 (23%), Positives = 38/113 (33%), Gaps = 5/113 (4%) Query: 442 TPQAPRTLGPSPPAPS-STPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFI 500 +P R PSPP + P P + PP R + P R P ++++ + Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656 Query: 501 QPRPTLNQPPPPLIRPANSMPPRL----NPRPVLSTVGGQQPPSLIGIQTDSQ 549 + P R A S P +PRP PP G + Q Sbjct: 657 SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQ 709 Score = 31.2 bits (69), Expect = 2.6 Identities = 27/110 (24%), Positives = 41/110 (37%), Gaps = 20/110 (18%) Query: 443 PQAPRTLGPSPPAPS-STPTPTAPIATLNQPPPLLRPT------LPAAPALHRQ------ 489 P RT P PP ++P+P + PPP R + P+ + HR+ Sbjct: 609 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR 668 Query: 490 -------PPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLST 532 P P ++ + +PR PP +R S P+ P ST Sbjct: 669 STREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718 Score = 30.0 bits (66), Expect = 5.8 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 15/103 (14%) Query: 439 EAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQAR 498 EA++PQ + PSP P AP T + PPP+ R ++P + P P + R Sbjct: 672 EARSPQPNKRHSPSP-------RPRAP-QTSSSPPPVRRGA-SSSPQRRQSPSPSTRPIR 722 Query: 499 FIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS-TVGGQQPPS 540 + P P I+ A S P+ R S +V G P+ Sbjct: 723 RVS-----RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 51.6 bits (122), Expect = 2e-06 Identities = 48/161 (29%), Positives = 60/161 (37%), Gaps = 25/161 (15%) Query: 402 WEAEQG-----------TQASNGDASTLGEETKSASNVPSGKSTD-EEEEAQTPQAPRTL 449 W A QG T+ ++ K++ N+PS E + P Sbjct: 818 WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVP 877 Query: 450 GPSPPAPSSTPTPTAPIATLNQPPPL-----LRPTLPAAPALHRQPPPLQQQARF--IQP 502 P PP P T PT P + QPPPL L P P P PPP A + P Sbjct: 878 PPPPPLPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936 Query: 503 RPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543 P PPPP + P ++P P P L G PP L G Sbjct: 937 LPGAGIPPPPPL-PGAAIP----PPPPLPGAGIPLPPPLPG 972 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/101 (38%), Positives = 43/101 (42%), Gaps = 14/101 (13%) Query: 451 PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 506 P PP P + P P P A + PPPL +P P L R PPP I P P L Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168 Query: 507 N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543 PPPPL P +P P P L VG PP L G Sbjct: 1169 PGAGIPPPPPL--PGVGIP----PPPPLPGVGIPPPPPLPG 1203 Score = 46.2 bits (108), Expect = 8e-05 Identities = 38/102 (37%), Positives = 43/102 (42%), Gaps = 14/102 (13%) Query: 451 PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 506 P PP P + P P P A + PPPL R +P P L PPP I P P L Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179 Query: 507 N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGI 544 PPPPL P +P P P L G PP L G+ Sbjct: 1180 PGVGIPPPPPL--PGVGIP----PPPPLPGAGIPPPPPLPGM 1215 Score = 44.7 bits (104), Expect = 2e-04 Identities = 38/108 (35%), Positives = 43/108 (39%), Gaps = 17/108 (15%) Query: 451 PSPPAPSST--PTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 506 P PP P + P P P A + PPPL +P P L PPP I P P L Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003 Query: 507 N----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 543 PPPPL P +PP + P P L G PP L G Sbjct: 1004 PGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049 Score = 43.9 bits (102), Expect = 4e-04 Identities = 39/114 (34%), Positives = 43/114 (37%), Gaps = 15/114 (13%) Query: 443 PQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFI 500 P A L P P P P P A + PPPL +P P L PPP I Sbjct: 960 PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019 Query: 501 QPRPTLN----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 543 P P L PPPPL P +PP + P P L G PP L G Sbjct: 1020 PPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/101 (36%), Positives = 41/101 (40%), Gaps = 14/101 (13%) Query: 451 PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 506 P PP P + P P P A + PPPL +P P L PPP I P P L Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102 Query: 507 N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 543 PPPPL P +P P P L G PP L G Sbjct: 1103 PGVGIPPPPPL--PGAGIP----PPPPLPGAGIPPPPPLPG 1137 Score = 40.8 bits (94), Expect = 0.003 Identities = 39/110 (35%), Positives = 42/110 (38%), Gaps = 19/110 (17%) Query: 451 PSPPAPSS-----TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPR 503 P PP P + P P A I PPPL +P P L PPP I P Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIP---PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1132 Query: 504 PTLN----QPPPPLIRPANSMPPRL-----NPRPVLSTVGGQQPPSLIGI 544 P L PPPPL R PP L P P L G PP L G+ Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1182 Score = 39.7 bits (91), Expect = 0.007 Identities = 39/111 (35%), Positives = 43/111 (38%), Gaps = 23/111 (20%) Query: 451 PSPPAPSS-----TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPR 503 P PP P + P P A I PPPL +P P L PPP I P Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1066 Query: 504 PTLN----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 543 P L PPPPL P +PP + P P L VG PP L G Sbjct: 1067 PPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG 1115 Score = 39.7 bits (91), Expect = 0.007 Identities = 27/71 (38%), Positives = 30/71 (42%), Gaps = 7/71 (9%) Query: 451 PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQ 508 P PP P P P P A + PPPL +P APA PPL I P P L Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA-----PPLPPPGTGIPPPPLLPV 1240 Query: 509 PPPPLIRPANS 519 PPL+ S Sbjct: 1241 SGPPLLPQVGS 1251 Score = 38.1 bits (87), Expect = 0.021 Identities = 38/112 (33%), Positives = 43/112 (38%), Gaps = 25/112 (22%) Query: 443 PQAPRTLGPSPPA------PSSTPTPTAPIATLNQPPPLLR---PTLPAAPALHRQPPPL 493 P PR P PP P P P A I PPPL P P P + PPP Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGVGIPPPPPLPGVGIPPPP- 1199 Query: 494 QQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVG-GQQPPSLIGI 544 P P PPPP + P +PP P P L G G PP L+ + Sbjct: 1200 --------PLPGAGIPPPPPL-PGMGIPPA--PAPPLPPPGTGIPPPPLLPV 1240 Score = 37.7 bits (86), Expect = 0.028 Identities = 44/135 (32%), Positives = 49/135 (36%), Gaps = 38/135 (28%) Query: 443 PQAPRTLG------PSPPAPSS-----TPTPTA--------PIATLNQPPPLLRPTLPAA 483 PQ P G P PP P + P P A P A + PPPL +P Sbjct: 897 PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956 Query: 484 PALHRQ----PPPLQQQARFIQPRPTLN----QPPPPLIRPANSMPP-------RLNPRP 528 P L PPPL I P P L PPPPL P +PP + P P Sbjct: 957 PPLPGAGIPLPPPLPGAG--IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPP 1012 Query: 529 VLSTVGGQQPPSLIG 543 L G PP L G Sbjct: 1013 PLPGAGIPPPPPLPG 1027 Score = 31.2 bits (69), Expect = 2.6 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 12/78 (15%) Query: 405 EQGTQASNGDA--STLGEE--TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTP 460 E+G + + DA + GEE + + P + EEEAQ GP PA +S P Sbjct: 347 EEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQ--------GPDAPAAASLP 398 Query: 461 TPTAPIATLNQPPPLLRP 478 AP +P PL+ P Sbjct: 399 GSPAPSQRCFKPYPLITP 416 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/130 (30%), Positives = 53/130 (40%), Gaps = 10/130 (7%) Query: 418 LGEETKSASNVPSGKSTDEEE----EAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPP 473 +G+ T ++ + G+ + E+ + + P AP T P TP A A P Sbjct: 618 VGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAP 677 Query: 474 PLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLN-QPPPPLIRPANSMPPRLNPRPVLST 532 L P P P L PPP Q F P P PPPP PA ++PP P L Sbjct: 678 TLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPP-----PPLPA 732 Query: 533 VGGQQPPSLI 542 G PP ++ Sbjct: 733 PPGVPPPPIL 742 Score = 40.4 bits (93), Expect = 0.004 Identities = 41/135 (30%), Positives = 50/135 (37%), Gaps = 22/135 (16%) Query: 405 EQGTQASNGDASTLGEETKSA--SNVPSGKSTDEEEEAQTPQAPRTLGPS---PPAPSST 459 ++G Q+S D +E SA ++ K A AP L P+ PP P Sbjct: 629 DEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFP 688 Query: 460 PTPTAPIATLNQP--------PPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPP 511 P P P QP PP P PA PA+ PPPL + P P L PP Sbjct: 689 PLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-VPPPPILPPLPP 747 Query: 512 PLIRPANSMPPRLNP 526 PP L P Sbjct: 748 --------FPPGLFP 754 Score = 34.3 bits (77), Expect = 0.31 Identities = 46/189 (24%), Positives = 60/189 (31%), Gaps = 34/189 (17%) Query: 396 EEVLQEWEAEQG-TQASNGDASTLGEETKSASNVPSGKSTDEEEE--------------A 440 EE +E AE+ A D GEE A P+ S EEE + Sbjct: 1146 EEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205 Query: 441 QTPQAPRTLGPSPPAPSSTP--------------TPTAPIATLNQPPPLLRPTLPAAPAL 486 + P +G PA S P +P P + PPL P Sbjct: 1206 MLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLE 1265 Query: 487 HRQPPPLQQQARFIQPRPTLNQP----PPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 542 PP+ P P P PPP ++ P + P P L+ P L Sbjct: 1266 VEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP-LAEDHPPHTPGLC 1324 Query: 543 GIQTDSQSS 551 G SQS+ Sbjct: 1325 GSLAKSQST 1333 Score = 33.1 bits (74), Expect = 0.68 Identities = 32/129 (24%), Positives = 44/129 (34%), Gaps = 17/129 (13%) Query: 429 PSGKSTDEEEEAQTPQAPRTLGPSPPA------PSSTP--TPTAPIATLNQPP-----PL 475 P+ EE + + L P PPA P +P P + +PP PL Sbjct: 1219 PADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPL 1278 Query: 476 LRPTLPAAPALHRQPPPLQQQARF----IQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 531 P P P PPP + + P P PP S+ + V + Sbjct: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPA 1338 Query: 532 TVGGQQPPS 540 T GG+ P S Sbjct: 1339 TPGGEPPLS 1347 Score = 30.8 bits (68), Expect = 3.4 Identities = 33/130 (25%), Positives = 40/130 (30%), Gaps = 19/130 (14%) Query: 409 QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIAT 468 +A D++T A P+ QTP A P P PT TA Sbjct: 369 KAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHF------PPPPEEPTATAAFGA 422 Query: 469 LNQ--------PPPL--LRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPAN 518 + PPPL P P PPP + + RPT P P P Sbjct: 423 RDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGT 482 Query: 519 SMPPRLNPRP 528 P L P Sbjct: 483 ---PTLESSP 489 Score = 30.8 bits (68), Expect = 3.4 Identities = 27/114 (23%), Positives = 40/114 (35%), Gaps = 21/114 (18%) Query: 429 PSGKSTDEEEEAQTPQA------PRTLGPSPPAPSSTPTPTAPIATLNQPP--------P 474 P ++TD + P+ P T G S T T P +PP Sbjct: 1295 PEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLS 1354 Query: 475 LLRPTLPAAPALHRQPPPL-------QQQARFIQPRPTLNQPPPPLIRPANSMP 521 L P +P +P + P P + R PT ++P PL+ P +P Sbjct: 1355 LSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLP 1408 Score = 30.4 bits (67), Expect = 4.4 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 5/92 (5%) Query: 428 VPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLN---QPPPLLRPTLPAAP 484 +P+G+ + +P T G P P P P A A L + P L P LPA P Sbjct: 1407 LPTGRRDERSGPLASPVLLET-GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPA-P 1464 Query: 485 ALHRQPPPLQQQARFIQPRPTLNQPPPPLIRP 516 PP ++ R + P++ PL+RP Sbjct: 1465 LASCPPPMKRKPGRPRRSPPSMLSLDGPLVRP 1496 >gi|112807226 hypothetical protein LOC91748 [Homo sapiens] Length = 1045 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 24/155 (15%) Query: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAK-----LDEYIAIAKEK-- 111 + VG+ +QA IP A D LVW P+ + ++ +++ + A Sbjct: 723 INVGSRFQAEIPLMRDRALAAADPHKAD-LVWQPWEDLESSREKQRQVEDLLTAACSSIF 781 Query: 112 --HGYNVEQALGMLFWHKHNIEKSLADL-------PNFTPFP-------DEWTVEDKVLF 155 G N E AL L + +I ++L L P+ P D+W + ++ LF Sbjct: 782 PGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLF 841 Query: 156 EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 190 + + + K F +Q+++ KT+A V++YY++KK Sbjct: 842 NKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKK 876 Score = 34.7 bits (78), Expect = 0.23 Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 23/114 (20%) Query: 347 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406 +W E+ L +G+ Y KDF + +I KTV Q F+ Y+++ + Sbjct: 832 QWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKI--------GRN 883 Query: 407 GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQ---TPQAPRTLGPSPPAPS 457 GT + GD T E KS EE E + + PR P +PS Sbjct: 884 GT-LTFGDVDTSDE-----------KSAQEEVEVDIKTSQKFPRVPLPRRESPS 925 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.129 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,197,759 Number of Sequences: 37866 Number of extensions: 1575621 Number of successful extensions: 21078 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 380 Number of HSP's successfully gapped in prelim test: 1233 Number of HSP's that attempted gapping in prelim test: 11375 Number of HSP's gapped (non-prelim): 6651 length of query: 553 length of database: 18,247,518 effective HSP length: 107 effective length of query: 446 effective length of database: 14,195,856 effective search space: 6331351776 effective search space used: 6331351776 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.