Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 209969819

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209969819 hypothetical protein LOC253143 [Homo sapiens]
         (2151 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209969819 hypothetical protein LOC253143 [Homo sapiens]           4318   0.0  
gi|13128980 proline rich 14 [Homo sapiens]                            146   2e-34
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     46   3e-04
gi|83367077 mucin 16 [Homo sapiens]                                    44   0.002
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]        40   0.019
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo...    40   0.019
gi|21735569 claspin [Homo sapiens]                                     40   0.025
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo...    39   0.042
gi|4506885 semenogelin II precursor [Homo sapiens]                     39   0.042
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    39   0.055
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa...    39   0.055
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa...    39   0.055
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        38   0.094
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           38   0.094
gi|120953264 folliculin interacting protein 1 isoform 2 [Homo sa...    37   0.16 
gi|120953291 folliculin interacting protein 1 isoform 1 [Homo sa...    37   0.16 
gi|4759344 centromere/kinetochore protein zw10 [Homo sapiens]          37   0.16 
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    37   0.21 
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    37   0.21 
gi|209862789 microtubule associated monoxygenase, calponin and L...    37   0.21 
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             37   0.27 
gi|148612831 kinesin family member 18A [Homo sapiens]                  37   0.27 
gi|139948432 adlican [Homo sapiens]                                    36   0.36 
gi|110349719 titin isoform N2-A [Homo sapiens]                         35   0.61 
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]              35   0.61 
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]             35   0.61 
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]             35   0.61 
gi|110349797 homer 2 isoform 4 [Homo sapiens]                          35   0.61 
gi|109637791 transcription factor-like nuclear regulator [Homo s...    35   0.61 
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom...    35   0.79 

>gi|209969819 hypothetical protein LOC253143 [Homo sapiens]
          Length = 2151

 Score = 4318 bits (11198), Expect = 0.0
 Identities = 2151/2151 (100%), Positives = 2151/2151 (100%)

Query: 1    MLSSGVETQPVPLDSSMSAVVQELYSELPVSVSRELHADPEPSVIPDVKPGASSSLLSQN 60
            MLSSGVETQPVPLDSSMSAVVQELYSELPVSVSRELHADPEPSVIPDVKPGASSSLLSQN
Sbjct: 1    MLSSGVETQPVPLDSSMSAVVQELYSELPVSVSRELHADPEPSVIPDVKPGASSSLLSQN 60

Query: 61   RALPLELQRTHVESCCEETYETLDHGSEPGRCGLVDSTAGGSVASGILDRAKRSESMEPK 120
            RALPLELQRTHVESCCEETYETLDHGSEPGRCGLVDSTAGGSVASGILDRAKRSESMEPK
Sbjct: 61   RALPLELQRTHVESCCEETYETLDHGSEPGRCGLVDSTAGGSVASGILDRAKRSESMEPK 120

Query: 121  VFRDPGGQAGIIREPSEGAKEDPHQHSTAAEEKTSPSQEDLLMQSSKELSHVDLPEDFLR 180
            VFRDPGGQAGIIREPSEGAKEDPHQHSTAAEEKTSPSQEDLLMQSSKELSHVDLPEDFLR
Sbjct: 121  VFRDPGGQAGIIREPSEGAKEDPHQHSTAAEEKTSPSQEDLLMQSSKELSHVDLPEDFLR 180

Query: 181  SKEGNVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNGNVSKDLSAGCGEFQEVDKIMTS 240
            SKEGNVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNGNVSKDLSAGCGEFQEVDKIMTS
Sbjct: 181  SKEGNVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNGNVSKDLSAGCGEFQEVDKIMTS 240

Query: 241  DEVSETSTLVTPEPLTFVDPVLTEATPKEKECEELKSCPWLSLPGNSAISNVDNGKEELC 300
            DEVSETSTLVTPEPLTFVDPVLTEATPKEKECEELKSCPWLSLPGNSAISNVDNGKEELC
Sbjct: 241  DEVSETSTLVTPEPLTFVDPVLTEATPKEKECEELKSCPWLSLPGNSAISNVDNGKEELC 300

Query: 301  KPNLVCEADDNHQQLHGHHNEQPSSTHDSPTATSPLKENSEVSCFTSDLSGPESRTISLE 360
            KPNLVCEADDNHQQLHGHHNEQPSSTHDSPTATSPLKENSEVSCFTSDLSGPESRTISLE
Sbjct: 301  KPNLVCEADDNHQQLHGHHNEQPSSTHDSPTATSPLKENSEVSCFTSDLSGPESRTISLE 360

Query: 361  NCGFEGGGLLKRSAEKTDSSYFYRGDDQGKNLASREENEERLLIPRSERGGPFLFNAREP 420
            NCGFEGGGLLKRSAEKTDSSYFYRGDDQGKNLASREENEERLLIPRSERGGPFLFNAREP
Sbjct: 361  NCGFEGGGLLKRSAEKTDSSYFYRGDDQGKNLASREENEERLLIPRSERGGPFLFNAREP 420

Query: 421  EKEISGRCSGEKEPVVSPKENIHNNCIQDSLHTGNSSSLMPNSFTEATEVMLNKNDLKIT 480
            EKEISGRCSGEKEPVVSPKENIHNNCIQDSLHTGNSSSLMPNSFTEATEVMLNKNDLKIT
Sbjct: 421  EKEISGRCSGEKEPVVSPKENIHNNCIQDSLHTGNSSSLMPNSFTEATEVMLNKNDLKIT 480

Query: 481  VHVQGNLTNPEDHKETFTNMSHPGGHSEESSFSSLMQIEEAGQTTPVEPNILSKSFYTKD 540
            VHVQGNLTNPEDHKETFTNMSHPGGHSEESSFSSLMQIEEAGQTTPVEPNILSKSFYTKD
Sbjct: 481  VHVQGNLTNPEDHKETFTNMSHPGGHSEESSFSSLMQIEEAGQTTPVEPNILSKSFYTKD 540

Query: 541  CNSLVSIQRNLEGNTQLNEASCNDFLFERKSIVSLMPEDQISPVSEVLKPKQGTALLLPS 600
            CNSLVSIQRNLEGNTQLNEASCNDFLFERKSIVSLMPEDQISPVSEVLKPKQGTALLLPS
Sbjct: 541  CNSLVSIQRNLEGNTQLNEASCNDFLFERKSIVSLMPEDQISPVSEVLKPKQGTALLLPS 600

Query: 601  PEFDYRPESEKVIQTSHDDIPLLDEQSIACEMNELSCTNELVVNKVESECVLNQQVSLNS 660
            PEFDYRPESEKVIQTSHDDIPLLDEQSIACEMNELSCTNELVVNKVESECVLNQQVSLNS
Sbjct: 601  PEFDYRPESEKVIQTSHDDIPLLDEQSIACEMNELSCTNELVVNKVESECVLNQQVSLNS 660

Query: 661  QEHANLPTDSLLHLNKEMPLATGRDAHQSHHPPLEGRADVIADIQTIPIQTKIKDISPPG 720
            QEHANLPTDSLLHLNKEMPLATGRDAHQSHHPPLEGRADVIADIQTIPIQTKIKDISPPG
Sbjct: 661  QEHANLPTDSLLHLNKEMPLATGRDAHQSHHPPLEGRADVIADIQTIPIQTKIKDISPPG 720

Query: 721  NQTCGASSNCPTLNIKPVSLERKKEMADSGTKALHSRLRSNKREAAGFPQVVSVIECHSV 780
            NQTCGASSNCPTLNIKPVSLERKKEMADSGTKALHSRLRSNKREAAGFPQVVSVIECHSV
Sbjct: 721  NQTCGASSNCPTLNIKPVSLERKKEMADSGTKALHSRLRSNKREAAGFPQVVSVIECHSV 780

Query: 781  QSQDISSCHRVRKNVSQENMCSASAAFKSSKISLQVDNSLITKYENAFQHRDHCCQGTGH 840
            QSQDISSCHRVRKNVSQENMCSASAAFKSSKISLQVDNSLITKYENAFQHRDHCCQGTGH
Sbjct: 781  QSQDISSCHRVRKNVSQENMCSASAAFKSSKISLQVDNSLITKYENAFQHRDHCCQGTGH 840

Query: 841  SVEKSSCKVSYTSQERELDGKETNGSLPGDKIRNKMVAGLLNSGISNKTIHTSSSIKLSE 900
            SVEKSSCKVSYTSQERELDGKETNGSLPGDKIRNKMVAGLLNSGISNKTIHTSSSIKLSE
Sbjct: 841  SVEKSSCKVSYTSQERELDGKETNGSLPGDKIRNKMVAGLLNSGISNKTIHTSSSIKLSE 900

Query: 901  EGLEGKEQDVSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSSFKNVKSVE 960
            EGLEGKEQDVSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSSFKNVKSVE
Sbjct: 901  EGLEGKEQDVSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSSFKNVKSVE 960

Query: 961  TLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVNHNQKDLLVSSG 1020
            TLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVNHNQKDLLVSSG
Sbjct: 961  TLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVNHNQKDLLVSSG 1020

Query: 1021 SNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIVYTDCSNKLAEGVLDVKASNLLDCG 1080
            SNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIVYTDCSNKLAEGVLDVKASNLLDCG
Sbjct: 1021 SNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIVYTDCSNKLAEGVLDVKASNLLDCG 1080

Query: 1081 ARQEKLAFQEDSRSTLSRRELDAAHTGTTGQDSDFPVTAASTVDFLKIKKSCEENVCRSL 1140
            ARQEKLAFQEDSRSTLSRRELDAAHTGTTGQDSDFPVTAASTVDFLKIKKSCEENVCRSL
Sbjct: 1081 ARQEKLAFQEDSRSTLSRRELDAAHTGTTGQDSDFPVTAASTVDFLKIKKSCEENVCRSL 1140

Query: 1141 KDCEMEKCPDSCAHEMESVADHEPNKRILGRVNLSLNDSHYGQQDKGTSLRETQEMTEGS 1200
            KDCEMEKCPDSCAHEMESVADHEPNKRILGRVNLSLNDSHYGQQDKGTSLRETQEMTEGS
Sbjct: 1141 KDCEMEKCPDSCAHEMESVADHEPNKRILGRVNLSLNDSHYGQQDKGTSLRETQEMTEGS 1200

Query: 1201 RLEPNSEFGKESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSETNVNSEETDLKN 1260
            RLEPNSEFGKESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSETNVNSEETDLKN
Sbjct: 1201 RLEPNSEFGKESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSETNVNSEETDLKN 1260

Query: 1261 LCKPKDGEMLCENVKDCTVLPEMKEIVSRDWSNSSDRDSVCTCVEKNACKACHPHENSSD 1320
            LCKPKDGEMLCENVKDCTVLPEMKEIVSRDWSNSSDRDSVCTCVEKNACKACHPHENSSD
Sbjct: 1261 LCKPKDGEMLCENVKDCTVLPEMKEIVSRDWSNSSDRDSVCTCVEKNACKACHPHENSSD 1320

Query: 1321 RHLPLTVKTDIKVKGEETEEHQRGRLGYLTVGEQSEELVTRETGDGDPVSNISQTHFKCR 1380
            RHLPLTVKTDIKVKGEETEEHQRGRLGYLTVGEQSEELVTRETGDGDPVSNISQTHFKCR
Sbjct: 1321 RHLPLTVKTDIKVKGEETEEHQRGRLGYLTVGEQSEELVTRETGDGDPVSNISQTHFKCR 1380

Query: 1381 GILNHAEKQQSPEVLDYMLQKEEKYIRQQKAHTISQQCISSSLLLDDAQNQNQPKADKDE 1440
            GILNHAEKQQSPEVLDYMLQKEEKYIRQQKAHTISQQCISSSLLLDDAQNQNQPKADKDE
Sbjct: 1381 GILNHAEKQQSPEVLDYMLQKEEKYIRQQKAHTISQQCISSSLLLDDAQNQNQPKADKDE 1440

Query: 1441 STMINEITLAKLAKDSIVAQTQKLEDQKEERLHHPLRKDTESCTSPCLLGAPRKAQDPSS 1500
            STMINEITLAKLAKDSIVAQTQKLEDQKEERLHHPLRKDTESCTSPCLLGAPRKAQDPSS
Sbjct: 1441 STMINEITLAKLAKDSIVAQTQKLEDQKEERLHHPLRKDTESCTSPCLLGAPRKAQDPSS 1500

Query: 1501 AGCDQIHGAFAKKGVLPLKKQPHRTCKKVSYQEQIIVGRKIGKIRSSAFLKSSSNPIPTK 1560
            AGCDQIHGAFAKKGVLPLKKQPHRTCKKVSYQEQIIVGRKIGKIRSSAFLKSSSNPIPTK
Sbjct: 1501 AGCDQIHGAFAKKGVLPLKKQPHRTCKKVSYQEQIIVGRKIGKIRSSAFLKSSSNPIPTK 1560

Query: 1561 AHRLLSLCTLSAPTRLEPETAPTKSLVSHIPKQMSTPCHPLRSLNFRKTTKESALLNKLS 1620
            AHRLLSLCTLSAPTRLEPETAPTKSLVSHIPKQMSTPCHPLRSLNFRKTTKESALLNKLS
Sbjct: 1561 AHRLLSLCTLSAPTRLEPETAPTKSLVSHIPKQMSTPCHPLRSLNFRKTTKESALLNKLS 1620

Query: 1621 ILASKLAPAMKTQKLRYRRCSSELLPMAKSYKRLRYKRLLDGFSSSTEQLNPYLAASGWD 1680
            ILASKLAPAMKTQKLRYRRCSSELLPMAKSYKRLRYKRLLDGFSSSTEQLNPYLAASGWD
Sbjct: 1621 ILASKLAPAMKTQKLRYRRCSSELLPMAKSYKRLRYKRLLDGFSSSTEQLNPYLAASGWD 1680

Query: 1681 KRPNSKPMALYSLESIKMTFIDLSNKMPSLLFGSEIFPVSFHVKSSSSDCTTESSRTFPE 1740
            KRPNSKPMALYSLESIKMTFIDLSNKMPSLLFGSEIFPVSFHVKSSSSDCTTESSRTFPE
Sbjct: 1681 KRPNSKPMALYSLESIKMTFIDLSNKMPSLLFGSEIFPVSFHVKSSSSDCTTESSRTFPE 1740

Query: 1741 HCAPARLALGEALQCPSQPPKWTFSFFLSHGCPGMATFREDTGVHSQTHTQAPPQPPAPL 1800
            HCAPARLALGEALQCPSQPPKWTFSFFLSHGCPGMATFREDTGVHSQTHTQAPPQPPAPL
Sbjct: 1741 HCAPARLALGEALQCPSQPPKWTFSFFLSHGCPGMATFREDTGVHSQTHTQAPPQPPAPL 1800

Query: 1801 QDYGGTAIVQTRADCSVLGLHTLLALCSPGCYRIWTKKRSFSSHMPTMQRLFMTQFTQGL 1860
            QDYGGTAIVQTRADCSVLGLHTLLALCSPGCYRIWTKKRSFSSHMPTMQRLFMTQFTQGL
Sbjct: 1801 QDYGGTAIVQTRADCSVLGLHTLLALCSPGCYRIWTKKRSFSSHMPTMQRLFMTQFTQGL 1860

Query: 1861 KGLRSPASIADKVFCSLPYSVGRVLSIWSQHGPSVCSFEISSLHSPHCKRQPSLGTTSSH 1920
            KGLRSPASIADKVFCSLPYSVGRVLSIWSQHGPSVCSFEISSLHSPHCKRQPSLGTTSSH
Sbjct: 1861 KGLRSPASIADKVFCSLPYSVGRVLSIWSQHGPSVCSFEISSLHSPHCKRQPSLGTTSSH 1920

Query: 1921 TMLPYVPLPGMEATYNTSGSQTRLEPPFPALVPKSCLVAESAVSKLLLSASEFQVRGLDE 1980
            TMLPYVPLPGMEATYNTSGSQTRLEPPFPALVPKSCLVAESAVSKLLLSASEFQVRGLDE
Sbjct: 1921 TMLPYVPLPGMEATYNTSGSQTRLEPPFPALVPKSCLVAESAVSKLLLSASEFQVRGLDE 1980

Query: 1981 LDGVKAACPCPQSSPPEQKEAEPEKRPKKVSQIRIRKTIPRPDPNLTPMGLPRPKRLKKK 2040
            LDGVKAACPCPQSSPPEQKEAEPEKRPKKVSQIRIRKTIPRPDPNLTPMGLPRPKRLKKK
Sbjct: 1981 LDGVKAACPCPQSSPPEQKEAEPEKRPKKVSQIRIRKTIPRPDPNLTPMGLPRPKRLKKK 2040

Query: 2041 EFSLEEIYTNKNYKSPPANRCLETIFEEPKERNGTLISISQQKRKRVLEFQDFTVPRKRR 2100
            EFSLEEIYTNKNYKSPPANRCLETIFEEPKERNGTLISISQQKRKRVLEFQDFTVPRKRR
Sbjct: 2041 EFSLEEIYTNKNYKSPPANRCLETIFEEPKERNGTLISISQQKRKRVLEFQDFTVPRKRR 2100

Query: 2101 ARGKVKVAGSFTRAQKAAVQSRELDALLIQKLMELETFFAKEEEQEQSSGC 2151
            ARGKVKVAGSFTRAQKAAVQSRELDALLIQKLMELETFFAKEEEQEQSSGC
Sbjct: 2101 ARGKVKVAGSFTRAQKAAVQSRELDALLIQKLMELETFFAKEEEQEQSSGC 2151


>gi|13128980 proline rich 14 [Homo sapiens]
          Length = 585

 Score =  146 bits (369), Expect = 2e-34
 Identities = 107/265 (40%), Positives = 130/265 (49%), Gaps = 43/265 (16%)

Query: 1892 GPSVCSFEISSLHSPHCKRQPSLGTTSSHTMLPYVPLPGMEATYNTSGSQTRLEPPFPAL 1951
            GP  C++       P    QPS      HT+                G   R  PP    
Sbjct: 341  GPGTCTW-------PPAPPQPSRPRPRRHTV--------------GGGEMARAPPP---- 375

Query: 1952 VPKSCLVAE-------SAVSKLLLSASEFQVRGLDE-----LDGVKAACPCPQSSPPEQK 1999
             P+ CL  E        A   L  S S        E     L   K   P    +  +Q 
Sbjct: 376  -PRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEP---RASKDQV 431

Query: 2000 EAEPE-KRPKKVSQIRIRKTIPRPDPNLTPMGLPRPKRLKKKEFSLEEIYTNKNYKSPPA 2058
             +EPE K   KVS+ RIR+T  RP  NLTPMGLPRP RL KKEFSLEEIYTNKNY+SP  
Sbjct: 432  LSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEEIYTNKNYQSPTT 491

Query: 2059 NRCLETIFEEPKERNGTLISISQQKRKRVLEFQDFTVPRKRRARGKVKVAGSFTRAQKAA 2118
             R  ETIFEEP+ERNGTLI  S +K +R +EF+D ++PR RR    V+ AG  T     A
Sbjct: 492  RRTFETIFEEPRERNGTLIFTSSRKLRRAVEFRDSSLPRSRRPSRGVRAAGGRTVPPNVA 551

Query: 2119 VQSRELDALLIQKLMELETFFAKEE 2143
              S ++  LL Q+L EL+    +EE
Sbjct: 552  -PSPDVGPLLQQRLEELDALLLEEE 575


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 118/616 (19%), Positives = 229/616 (37%), Gaps = 97/616 (15%)

Query: 131 IIREPSEGAK------EDPHQHSTAAEEKTSPSQEDLLMQSSKELSHVDLPEDFLRSKEG 184
           I+R  +E  K      E+ H+ S    ++ S S  + L Q   E+SH+   +  L+ +  
Sbjct: 63  ILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQKEVEISHLKARQIALQDQLL 122

Query: 185 NVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNGNVSKDLSAGCGEFQEVDKIMTSDEVS 244
            +Q  A+++   A V     + +       H +     D+  G       D I +  E++
Sbjct: 123 KLQSAAQSVPSGAGVPATTASSSFAYGISHHPSAFHDDDMDFG-------DIISSQQEIN 175

Query: 245 ETSTLVTPEPLTFVDPVLTEATPKEKECEELKSCPWLSLPGNSAISNVDNGKE-ELCK-P 302
             S                E +  E E        W  +   S     DN  + E+CK  
Sbjct: 176 RLSN---------------EVSRLESEVGH-----WRHIAQTSKAQGTDNSDQSEICKLQ 215

Query: 303 NLVCEADDNHQQLHGHHNEQPSSTHDSPTATSPLKENSEVSC-FTSDLSGPESRTISLEN 361
           N++ E   N  Q    H  + S   ++       ++ +E+S     +LS  E R   LEN
Sbjct: 216 NIIKELKQNRSQEIDDHQHEMSVLQNAHQ-----QKLTEISRRHREELSDYEERIEELEN 270

Query: 362 CGFEGGGLLKRSAEKTDSSYFYRGDD--QGKNLASREENEERLLIPRSERGGPFLFNARE 419
              +GG        +TD S  Y      Q   +   E  ++   +    +      ++ E
Sbjct: 271 LLQQGGS----GVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAE 326

Query: 420 PEKEISGRCSGEKEPVVSPKENIHNNCIQDSLHTGN---SSSLMPNSFTEATEVMLNKND 476
            +++I  R   E+E +   K  I   C    L       S+    ++ TE   ++     
Sbjct: 327 NDRDILRR---EQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSAS 383

Query: 477 LKITVHVQGNLTNPEDHKETFTNMSHPGGHSE------------ESSFSSLMQIEEAGQT 524
           ++    +Q  L++ E+     ++++     +E            E   S L Q +E  Q 
Sbjct: 384 VEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQM 443

Query: 525 TPVEPNI---LSKSFYTKDCNSLVSIQRNLEGNTQLNEASCNDFLFERKSIVSLMPE--- 578
           + ++ N    + KS  T+D  SL S   +L  N +  E   N  + E++++++ + E   
Sbjct: 444 SLLKLNNEYEVIKSTATRDI-SLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDR 502

Query: 579 -------DQISPVSEVLKPKQGTALLLPSPEFDYRPESEKVIQTSHDDIPLLDEQSIACE 631
                    I    ++ K +     ++   + D   E ++V Q   D + +  E  +  E
Sbjct: 503 QNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKE 562

Query: 632 --------MNELSCTNELVVNKVES----------ECVLNQQVSLNSQEHANLPTDSLLH 673
                   +N+L  T + + +KVE+            V  Q+ +L  +EH     + L  
Sbjct: 563 KLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSR 622

Query: 674 LNKEMPLATGRDAHQS 689
           +  E+  +  +D++ +
Sbjct: 623 IRNELMQSLNQDSNSN 638


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 4/153 (2%)

Query: 8     TQPVPLDSSMSAVVQELYSELPVSVSRELHADPEPSVIPDVKPGASSSLLSQNRALPLEL 67
             T+  P D+++S + + L S  PV  S       + S IP +    SSS         L  
Sbjct: 10308 TESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGT 10367

Query: 68    QRTHVESCCEETYETLDHGSEPGRCG---LVDSTAGGSVASGILDRAKRSESMEPKVFRD 124
             + +  E        TLD  S+PGR     ++D+    SV  G +  A +  S+  ++ R 
Sbjct: 10368 ESSTTEGRL-VMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRT 10426

Query: 125   PGGQAGIIREPSEGAKEDPHQHSTAAEEKTSPS 157
              G    I + P+E A     +     +  TSP+
Sbjct: 10427 DGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPA 10459



 Score = 32.7 bits (73), Expect = 3.9
 Identities = 76/373 (20%), Positives = 142/373 (38%), Gaps = 51/373 (13%)

Query: 3    SSGVETQPVPLDSSMSAVVQELYSELPVSVSRELHADPEPSVIPDVKPG------ASSSL 56
            SS +ET  V  + S+ A  +   +E+  S    +    E +++P++          +S +
Sbjct: 7258 SSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPI 7317

Query: 57   LSQNRALPLELQRTHVESCCEETYETLDHGSEPGRC--------GLVDSTAGGSVASGIL 108
            L+++  + ++ Q +   S  E T+ TLD  + P            L  S     V+ G  
Sbjct: 7318 LAESSEMTIKTQTSPPGSTSESTF-TLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAG 7376

Query: 109  DRAKRSESMEPKVFRDPGGQAGI--IREPSEGAKEDPHQHSTAAEEKTSPSQEDLLMQSS 166
            D   R  S+  +    P  Q  +  +  PS  +   P     A+   +S S   LL    
Sbjct: 7377 D-VPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLP-----ASSHSSSASVTSLLTPGQ 7430

Query: 167  KELSHV-DLPEDFLRSKEGNVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNGNVSKDLS 225
             + + V D   +   S   ++  T+  +L ++EV       T T+      N  V+K  +
Sbjct: 7431 VKTTEVLDASAEPETSSPPSLSSTSVEILATSEVT------TDTEKIHPFSNTAVTKVGT 7484

Query: 226  AGCGEFQEVDKIMTSDEVSETSTLVTPEPLTFVDPVLTEATPKEKECEELKSCPWLSLPG 285
            +  G       +  S+    TS + T   +   D  ++  TP      +++S P  SL  
Sbjct: 7485 SSSGHESPSSVLPDSETTKATSAMGTISIMG--DTSVSTLTPALSNTRKIQSEPASSL-- 7540

Query: 286  NSAISNVDNGKEELCKPNLVCEADDNHQQLHGHHNEQPSSTHDSPTATSPLKENSEVSCF 345
             + +      +E     +L  EA+    ++             S  AT+ +     +S  
Sbjct: 7541 TTRLRETSTSEE----TSLATEANTVLSKV-------------STGATTEVSRTEAISFS 7583

Query: 346  TSDLSGPESRTIS 358
             + +SGPE  T+S
Sbjct: 7584 RTSMSGPEQSTMS 7596


>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
          Length = 917

 Score = 40.4 bits (93), Expect = 0.019
 Identities = 62/265 (23%), Positives = 108/265 (40%), Gaps = 34/265 (12%)

Query: 1225 HDESSVSLRSLKSIEIMPSQENSE----TNVNSEETDLKNLCKPKD--GEMLCENVKDCT 1278
            H       +  K IEI+  +EN+E    T   +EET  K + +       ++ EN    +
Sbjct: 580  HQNQETENKYFKDIEII--KENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637

Query: 1279 VLPEMKEIVSRDWSNSSDRDSVCTCVEKNACKAC-----HPHENSSDRHLPLTVKTDIKV 1333
             L + K+ +SR          + T +E   C+       H    SS R L L  ++ +  
Sbjct: 638  ELQKEKQSMSR----------LETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNE 687

Query: 1334 ---KGEETEEHQRGRLGYLTVGEQSEELVTRETGDGDPVSNISQTHFK-CRGILNHAEKQ 1389
                 E+T  H +     L+  E +   +  E             H +  +G+L+  +++
Sbjct: 688  WCHLQEDTNSHIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRR 747

Query: 1390 QSPEVLDYMLQKE----EKYIR-QQKAHTISQQCISSSLLLDDAQNQNQPKADKDESTMI 1444
               E +++M Q +    EKY+R QQ       Q  S +LL     N  + KAD  E T+I
Sbjct: 748  L--EDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTII 805

Query: 1445 NEITLAKLAKDSIVAQTQKLEDQKE 1469
            N     +   + + A+ +KLE+  +
Sbjct: 806  NIQVKCEDTVEKLQAECRKLEENNK 830


>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
            sapiens]
          Length = 917

 Score = 40.4 bits (93), Expect = 0.019
 Identities = 62/265 (23%), Positives = 108/265 (40%), Gaps = 34/265 (12%)

Query: 1225 HDESSVSLRSLKSIEIMPSQENSE----TNVNSEETDLKNLCKPKD--GEMLCENVKDCT 1278
            H       +  K IEI+  +EN+E    T   +EET  K + +       ++ EN    +
Sbjct: 580  HQNQETENKYFKDIEII--KENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637

Query: 1279 VLPEMKEIVSRDWSNSSDRDSVCTCVEKNACKAC-----HPHENSSDRHLPLTVKTDIKV 1333
             L + K+ +SR          + T +E   C+       H    SS R L L  ++ +  
Sbjct: 638  ELQKEKQSMSR----------LETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNE 687

Query: 1334 ---KGEETEEHQRGRLGYLTVGEQSEELVTRETGDGDPVSNISQTHFK-CRGILNHAEKQ 1389
                 E+T  H +     L+  E +   +  E             H +  +G+L+  +++
Sbjct: 688  WCHLQEDTNSHIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRR 747

Query: 1390 QSPEVLDYMLQKE----EKYIR-QQKAHTISQQCISSSLLLDDAQNQNQPKADKDESTMI 1444
               E +++M Q +    EKY+R QQ       Q  S +LL     N  + KAD  E T+I
Sbjct: 748  L--EDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTII 805

Query: 1445 NEITLAKLAKDSIVAQTQKLEDQKE 1469
            N     +   + + A+ +KLE+  +
Sbjct: 806  NIQVKCEDTVEKLQAECRKLEENNK 830


>gi|21735569 claspin [Homo sapiens]
          Length = 1339

 Score = 40.0 bits (92), Expect = 0.025
 Identities = 38/136 (27%), Positives = 64/136 (47%), Gaps = 15/136 (11%)

Query: 110 RAKRSESMEPKVFRDPGGQAGIIREPSEGAKEDPHQHSTAAEEKTSPSQEDLLMQSSKEL 169
           +AK  E+M+ + F +   +  + +  +E   E+  +     EE T  S+ED   +  KE 
Sbjct: 598 KAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEE---EEMTDESEEDGEEKVEKEE 654

Query: 170 SHVDLPEDFLRSKE----GNVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNGNVSKDLS 225
              +L E+  + +E    GN Q TAE LL S E++      TK +     +N + S ++ 
Sbjct: 655 KEEELEEEEEKEEEEEEEGN-QETAEFLLSSEEIE------TKDEKEMDKENNDGSSEIG 707

Query: 226 AGCGEFQEVDKIMTSD 241
              G F  V K ++SD
Sbjct: 708 KAVG-FLSVPKSLSSD 722


>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
            sapiens]
          Length = 917

 Score = 39.3 bits (90), Expect = 0.042
 Identities = 60/264 (22%), Positives = 108/264 (40%), Gaps = 32/264 (12%)

Query: 1225 HDESSVSLRSLKSIEIMPSQENSETNVNSEETDLKNLCKPKDGEMLCENV----KDCTVL 1280
            H       +  K IEI+  +EN+E        DL+   K ++ E L + +    K+  VL
Sbjct: 580  HQNQETENKYFKDIEII--KENNE--------DLEKTLK-RNEEALTKTITRYSKELNVL 628

Query: 1281 PEMKEIVSRDWSNSSDRDS-VCTCVEKNACKAC-----HPHENSSDRHLPLTVKTDIKV- 1333
             +   +++ +        S + T +E   C+       H    SS R L L  ++ +   
Sbjct: 629  MDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEW 688

Query: 1334 --KGEETEEHQRGRLGYLTVGEQSEELVTRETGDGDPVSNISQTHFK-CRGILNHAEKQQ 1390
                E+T  H +     L+  E +   +  E             H +  +G+L+  +++ 
Sbjct: 689  CHLQEDTNSHIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRL 748

Query: 1391 SPEVLDYMLQKE----EKYIR-QQKAHTISQQCISSSLLLDDAQNQNQPKADKDESTMIN 1445
              E +++M Q +    EKY+R QQ       Q  S +LL     N  + KAD  E T+IN
Sbjct: 749  --EDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIIN 806

Query: 1446 EITLAKLAKDSIVAQTQKLEDQKE 1469
                 +   + + A+ +KLE+  +
Sbjct: 807  IQVKCEDTVEKLQAECRKLEENNK 830


>gi|4506885 semenogelin II precursor [Homo sapiens]
          Length = 582

 Score = 39.3 bits (90), Expect = 0.042
 Identities = 69/330 (20%), Positives = 129/330 (39%), Gaps = 63/330 (19%)

Query: 373 SAEKTDSSYFYRGDDQGKNLASREENEERLLIPRSERGGPFLFNAREPEKEISGRCSGEK 432
           S E+  +S   +G  QG + +S     E L++ + +R           E + S +  G  
Sbjct: 172 SKEQASASGAQKGRTQGGSQSSYVLQTEELVVNKQQR-----------ETKNSHQNKGHY 220

Query: 433 EPVVSPKENIHNNCIQDSLHTGNSSSLM---PNSFTEATEVML-NKNDLKITVHVQGNLT 488
           + VV  +E  H++ +Q SLH  +   L     + FT   E+++ NKN      H   NL+
Sbjct: 221 QNVVDVREE-HSSKLQTSLHPAHQDRLQHGPKDIFTTQDELLVYNKNQ-----HQTKNLS 274

Query: 489 NPEDHKETFTNMSHPGGHSEESSF-----SSLMQIEEAGQTTPVEPNILSKS-----FYT 538
             ++H      +S+P   +EE        S    + +   +   E  I  KS      ++
Sbjct: 275 QDQEHGRKAHKISYPSSRTEERQLHHGEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHS 334

Query: 539 KD-----CNSLVSIQRNLEGNTQLNEASCNDFLFER---KSIVSLMPEDQISPVSEVLKP 590
           +D       + +S Q     +T+    +C +   ++   K  +S+  E+QI   S+    
Sbjct: 335 QDQEHGHKENKISYQ---SSSTEERHLNCGEKGIQKGVSKGSISIQTEEQIHGKSQ---- 387

Query: 591 KQGTALLLPSPEFDYRPESEKVIQTSHDDIPLLDEQSIACEMNELSCTNELV---VNKVE 647
                + +PS   +Y  +  K+             QS + E   L+   + V   V+K  
Sbjct: 388 ---NQVRIPSQAQEYGHKENKI-----------SYQSSSTEERRLNSGEKDVQKGVSKGS 433

Query: 648 SECVLNQQVSLNSQEHANLPTDSLLHLNKE 677
                 +++   SQ    +P+    H +KE
Sbjct: 434 ISIQTEEKIHGKSQNQVTIPSQDQEHGHKE 463


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 38.9 bits (89), Expect = 0.055
 Identities = 69/372 (18%), Positives = 124/372 (33%), Gaps = 32/372 (8%)

Query: 951  SSFKNVKSVETLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVNH 1010
            S   N          +D      S+ ++ D  KSE  S+     SD +   ++ +   + 
Sbjct: 596  SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS----DSDSKSDSSDSNSSDSS 651

Query: 1011 NQKDLLVSSGSNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIVYTDCSNKLAEGVLD 1070
            +  D   SS S+NS         +   +    S   +S++       +D SN  +E    
Sbjct: 652  DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS------SDSSNS-SESSDS 704

Query: 1071 VKASNLLDCGARQEKLAFQEDSRSTLSRRELDAAHTGTTGQDSDFPVTAASTVDFLKIKK 1130
              +S+     +     +   DS S+ S    D++++  +   SD   ++ S+        
Sbjct: 705  SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764

Query: 1131 SCEENVCRSLKDCEMEKCPDSCAHEMESVADHEPNKRILGRVNLSLNDSHYGQQDKGTSL 1190
            S   +   S    +     DS      S +    N       + S + S     D   S 
Sbjct: 765  SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824

Query: 1191 --RETQEMTEGSRLEPNSEFGKESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSE 1248
                + + ++ S    +S+    S    S   + S    SS S  S  S     S ++S+
Sbjct: 825  DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884

Query: 1249 TNVNSEETDLKNLCKPKDGEMLCENVKDCTVLPEMKEIVSRDWSNSSDRDSVCTCVEKNA 1308
            +N +S  +D  +     D +                   S D SNSSD        + + 
Sbjct: 885  SNESSNSSDSSDSSNSSDSD-------------------SSDSSNSSDSSDSSNSSDSSE 925

Query: 1309 CKACHPHENSSD 1320
                  + NSSD
Sbjct: 926  SSNSSDNSNSSD 937



 Score = 38.9 bits (89), Expect = 0.055
 Identities = 94/546 (17%), Positives = 177/546 (32%), Gaps = 14/546 (2%)

Query: 779  SVQSQDISSCHRVRKNVSQENMCSASAAFKSSKISLQVDNSLITKYENAFQHRDHCCQGT 838
            S  S D  S      + S  +   +S +  SS  S   D+S  +   N+    D      
Sbjct: 704  SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD------ 757

Query: 839  GHSVEKSSCKVSYTSQERELDGKETNGSLPGDKIRNKMVAGLLNSGISNKTIHTSSSIKL 898
              S + S+   S  S +       +N S   D   +   +   NS  S+ +  +S S   
Sbjct: 758  --SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815

Query: 899  SEEGLEGKEQDVSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSSFKNVKS 958
            S+          +        N SD +    +   +        D S +   S   +  +
Sbjct: 816  SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875

Query: 959  VETLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVNHNQKDLLVS 1018
                   +D      S+ +      S+  S+    SSD  ++        + N  D   S
Sbjct: 876  SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS 935

Query: 1019 SGSNNSLPCG----SPKKCNLKGAFVKMSGCDESTEGMVDIVYTDCSNKLAEGVLDVKAS 1074
            S S+NS        S    +   +    +  D S     D   +  S+  ++      +S
Sbjct: 936  SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995

Query: 1075 NLLDCGARQEKLAFQEDSRSTLSRRELDAAHTGTTGQDSDFPVTAASTVDFLKIKKSCEE 1134
            +  D     +     + S S+ S    +++ +  +   SD   ++ S+        S   
Sbjct: 996  DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055

Query: 1135 NVCRSLKDCEMEKCPDSCAHEMESVADHEPNKRILGRVNLSLNDSHYGQQDKGTSLRETQ 1194
            N   S    +     DS      S +    +       + S + S        +   ++ 
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115

Query: 1195 EMTEGSRLEPNSEFGKESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSETNVNSE 1254
            + ++ S    +S+    S    SS  S S   +SS S  S  S +   S ++S+++ +S+
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDS--SDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173

Query: 1255 ETDLKNLCKPKDGEMLCENVKDCTVLPEMKEIVSRDWSNSSDRDSVCTCVEKNACKACHP 1314
             +D  N     D     ++              S D S+SSD        + +     + 
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233

Query: 1315 HENSSD 1320
              +SSD
Sbjct: 1234 SSDSSD 1239


>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
            sapiens]
          Length = 1782

 Score = 38.9 bits (89), Expect = 0.055
 Identities = 94/436 (21%), Positives = 167/436 (38%), Gaps = 59/436 (13%)

Query: 900  EEGLEGKEQDVSKETV--FCKYNISDHAIQELNQ-TVNIP---GPEKVLDQSPTVMFSSF 953
            E+ LE  +++VS ETV    K   +  A Q  ++ T ++P   G E  +D   TV     
Sbjct: 1240 EDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKV 1299

Query: 954  KNV----KSVETLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVN 1009
              V    +  E  + K D+ L+ QS+   P          +EM+   +RE        VN
Sbjct: 1300 TEVALKGEGTEEAECKKDDALELQSHAKSPPS-----PVEREMVVQVEREKTEAEPTHVN 1354

Query: 1010 HNQKD----LLVSSGSNNSL------PC--GSPKKCNLKGAFVKMSGCDESTEGMVDIVY 1057
              + +    + VS   +  L      P   G+ +  +L+G+     G +E+    + +  
Sbjct: 1355 EEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQS 1414

Query: 1058 TDCSNKLAEGVLDVKA----SNLLDCGARQEK----LAFQEDSRSTLSRRELDAAHTGT- 1108
            ++ S  L     + K     +N+L+ G   E     L  +E S     + E  AAH G  
Sbjct: 1415 SEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEKSSE---KNEDFAAHPGED 1471

Query: 1109 ---TGQD----SDFPVTAASTVDFLKIKKSCEENVCRSLKDCEMEKCPDSCAHEMESVA- 1160
               TG D    S   + +A+T   L      E+      K  E+++   +C     SVA 
Sbjct: 1472 AVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDE-QVACQEVKVSVAI 1530

Query: 1161 -DHEPNKRILGRVNLSLN----------DSHYGQQDKGTSLRETQEMTEGSRLEPNSEFG 1209
             D EP   IL     S            D     ++  T +  ++  T+   ++ +S+  
Sbjct: 1531 EDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDA 1590

Query: 1210 KESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSETNVNSEETDLKNLCKPKDGEM 1269
             + T     +   S  DE+ ++    +S      Q +S+ + +  E   K +    +G  
Sbjct: 1591 GQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGST 1650

Query: 1270 LCENVKDCTVLPEMKE 1285
            + +   +  VLP  +E
Sbjct: 1651 VNDQQLEEVVLPSEEE 1666


>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
            sapiens]
          Length = 1684

 Score = 38.9 bits (89), Expect = 0.055
 Identities = 94/436 (21%), Positives = 167/436 (38%), Gaps = 59/436 (13%)

Query: 900  EEGLEGKEQDVSKETV--FCKYNISDHAIQELNQ-TVNIP---GPEKVLDQSPTVMFSSF 953
            E+ LE  +++VS ETV    K   +  A Q  ++ T ++P   G E  +D   TV     
Sbjct: 1142 EDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKV 1201

Query: 954  KNV----KSVETLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVN 1009
              V    +  E  + K D+ L+ QS+   P          +EM+   +RE        VN
Sbjct: 1202 TEVALKGEGTEEAECKKDDALELQSHAKSPPS-----PVEREMVVQVEREKTEAEPTHVN 1256

Query: 1010 HNQKD----LLVSSGSNNSL------PC--GSPKKCNLKGAFVKMSGCDESTEGMVDIVY 1057
              + +    + VS   +  L      P   G+ +  +L+G+     G +E+    + +  
Sbjct: 1257 EEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQS 1316

Query: 1058 TDCSNKLAEGVLDVKA----SNLLDCGARQEK----LAFQEDSRSTLSRRELDAAHTGT- 1108
            ++ S  L     + K     +N+L+ G   E     L  +E S     + E  AAH G  
Sbjct: 1317 SEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEKSSE---KNEDFAAHPGED 1373

Query: 1109 ---TGQD----SDFPVTAASTVDFLKIKKSCEENVCRSLKDCEMEKCPDSCAHEMESVA- 1160
               TG D    S   + +A+T   L      E+      K  E+++   +C     SVA 
Sbjct: 1374 AVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDE-QVACQEVKVSVAI 1432

Query: 1161 -DHEPNKRILGRVNLSLN----------DSHYGQQDKGTSLRETQEMTEGSRLEPNSEFG 1209
             D EP   IL     S            D     ++  T +  ++  T+   ++ +S+  
Sbjct: 1433 EDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDA 1492

Query: 1210 KESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSETNVNSEETDLKNLCKPKDGEM 1269
             + T     +   S  DE+ ++    +S      Q +S+ + +  E   K +    +G  
Sbjct: 1493 GQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGST 1552

Query: 1270 LCENVKDCTVLPEMKE 1285
            + +   +  VLP  +E
Sbjct: 1553 VNDQQLEEVVLPSEEE 1568


>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 1524

 Score = 38.1 bits (87), Expect = 0.094
 Identities = 61/260 (23%), Positives = 96/260 (36%), Gaps = 48/260 (18%)

Query: 182 KEGNVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNGNVSKD----LSAGCGEFQEVDKI 237
           K G V    +  LK+   +   V+   T+  +G K+G VS      L+A   E   V  I
Sbjct: 430 KSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSI 489

Query: 238 MTSDEVSETSTLVTPEPLTFVDPVLTEATPKEKECEELKSCPWLSLPGNSAISNVDNGKE 297
              ++  E S  V+        P L +AT  EK+                + SN+  GK+
Sbjct: 490 ARENKDGEKSRTVSSRK----KPAL-KATSDEKD----------------SFSNITRGKK 528

Query: 298 ELCKPNLVCEADDNHQQLHGHHNEQPSSTHDSPTATSPLKENSEVSCFTSDLSGPESRTI 357
           +                  G  + + SS        +  +E+S +     +  G +SRT+
Sbjct: 529 D------------------GEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTV 570

Query: 358 SLENCGFEGGGLLKRSAEKTDSSYFYRGDDQGKNLASREENEERLLIPRSERGGPFLFNA 417
           S E    +  GL   SAEK       RG   G+        ++  L   S+    F    
Sbjct: 571 SSE----KPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNIT 626

Query: 418 RE-PEKEISGRCSGEKEPVV 436
           RE  + EIS + S +K P +
Sbjct: 627 REKKDGEISRKVSSQKPPAL 646


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 38.1 bits (87), Expect = 0.094
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 7/58 (12%)

Query: 1991 PQSSPPEQKEAEPEKRPKKVSQIRIRKTIPRPDPNLTPMGLPRPKRLKKKEFSLEEIY 2048
            P  SP  + E EPE  P+ V        +P P+P   P  LP P  L + EF  E ++
Sbjct: 99   PVGSPEPESEPEPEPEPEPVP-------VPPPEPQPEPQPLPDPAPLPELEFESERVH 149


>gi|120953264 folliculin interacting protein 1 isoform 2 [Homo
            sapiens]
          Length = 1138

 Score = 37.4 bits (85), Expect = 0.16
 Identities = 88/454 (19%), Positives = 163/454 (35%), Gaps = 88/454 (19%)

Query: 894  SSIKLSEEGLEGKEQD-VSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSS 952
            S ++L+   + GK QD V +   F  Y I    +QE +   N  G ++ +    TV+ ++
Sbjct: 487  SPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLEN--GEDEAIVMPGTVITTT 544

Query: 953  FKNVKSVE------TLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHG 1006
             +  +  E      T+ +    +L  +S + R   C  +   +  +L  +      +   
Sbjct: 545  LEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCK-YCSHPLLGQNVENISQQERE 603

Query: 1007 EVNHNQKDLLVSSGSNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIV-YTD----CS 1061
            ++ ++ K+LL           G   +C +    +  S C E  E  VD+  Y D    C 
Sbjct: 604  DIQNSSKELL-----------GISDECQM----ISPSDCQE--ENAVDVKQYRDKLRTCF 646

Query: 1062 NKLAEGVLDVKASNLLDCGARQEKLAFQEDSRSTLSRRELDA-AHTGTTGQDSDFPVTAA 1120
            +   E V+   +  +  C   +  L   E++    S + LD+ +HTG   + +   V   
Sbjct: 647  DAKLETVVCTGSVPVDKCALSESGLESTEETWQ--SEKLLDSDSHTGKAMRSTGMVVEKK 704

Query: 1121 STVDFLKIKKSCEENVCRSLKDCEMEKCPDSCAH-EMESVADH------EPNKRILGRVN 1173
                 +    SCE    +          PDS      ++V D       +P K   G ++
Sbjct: 705  PPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAID 764

Query: 1174 LSLNDSHYGQQDKGTSLRETQEMTEGSRLEPNSEFGKESTFGISSKESMSCHDE----SS 1229
                     +   G S  +TQ M      E          +  S  ESMS  DE     S
Sbjct: 765  QHQETKQTTKDQSGES--DTQNMVSEEPCEL-------PCWNHSDPESMSLFDEYFNDDS 815

Query: 1230 VSLRSLKSIEIMPSQENSETNVNSEETDLKNLCKPKDGEMLCENVKDCTVLPEMKEIVSR 1289
            +  R++  +    S ++ +           + C  +  ++LC                  
Sbjct: 816  IETRTIDDVPFKTSTDSKD-----------HCCMLEFSKILCTK---------------- 848

Query: 1290 DWSNSSDRDSVCTCVE---KNACKACHPHENSSD 1320
               N+   +  C C+E   +++CK C P ++  D
Sbjct: 849  ---NNKQNNEFCKCIETVPQDSCKTCFPQQDQRD 879


>gi|120953291 folliculin interacting protein 1 isoform 1 [Homo
            sapiens]
          Length = 1166

 Score = 37.4 bits (85), Expect = 0.16
 Identities = 88/454 (19%), Positives = 163/454 (35%), Gaps = 88/454 (19%)

Query: 894  SSIKLSEEGLEGKEQD-VSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSS 952
            S ++L+   + GK QD V +   F  Y I    +QE +   N  G ++ +    TV+ ++
Sbjct: 515  SPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLEN--GEDEAIVMPGTVITTT 572

Query: 953  FKNVKSVE------TLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHG 1006
             +  +  E      T+ +    +L  +S + R   C  +   +  +L  +      +   
Sbjct: 573  LEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCK-YCSHPLLGQNVENISQQERE 631

Query: 1007 EVNHNQKDLLVSSGSNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIV-YTD----CS 1061
            ++ ++ K+LL           G   +C +    +  S C E  E  VD+  Y D    C 
Sbjct: 632  DIQNSSKELL-----------GISDECQM----ISPSDCQE--ENAVDVKQYRDKLRTCF 674

Query: 1062 NKLAEGVLDVKASNLLDCGARQEKLAFQEDSRSTLSRRELDA-AHTGTTGQDSDFPVTAA 1120
            +   E V+   +  +  C   +  L   E++    S + LD+ +HTG   + +   V   
Sbjct: 675  DAKLETVVCTGSVPVDKCALSESGLESTEETWQ--SEKLLDSDSHTGKAMRSTGMVVEKK 732

Query: 1121 STVDFLKIKKSCEENVCRSLKDCEMEKCPDSCAH-EMESVADH------EPNKRILGRVN 1173
                 +    SCE    +          PDS      ++V D       +P K   G ++
Sbjct: 733  PPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAID 792

Query: 1174 LSLNDSHYGQQDKGTSLRETQEMTEGSRLEPNSEFGKESTFGISSKESMSCHDE----SS 1229
                     +   G S  +TQ M      E          +  S  ESMS  DE     S
Sbjct: 793  QHQETKQTTKDQSGES--DTQNMVSEEPCEL-------PCWNHSDPESMSLFDEYFNDDS 843

Query: 1230 VSLRSLKSIEIMPSQENSETNVNSEETDLKNLCKPKDGEMLCENVKDCTVLPEMKEIVSR 1289
            +  R++  +    S ++ +           + C  +  ++LC                  
Sbjct: 844  IETRTIDDVPFKTSTDSKD-----------HCCMLEFSKILCTK---------------- 876

Query: 1290 DWSNSSDRDSVCTCVE---KNACKACHPHENSSD 1320
               N+   +  C C+E   +++CK C P ++  D
Sbjct: 877  ---NNKQNNEFCKCIETVPQDSCKTCFPQQDQRD 907


>gi|4759344 centromere/kinetochore protein zw10 [Homo sapiens]
          Length = 779

 Score = 37.4 bits (85), Expect = 0.16
 Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 11/125 (8%)

Query: 506 HSEESSFSSLMQIEEAGQTTPVEPNILSKSFYTK-DCNSLVSIQRNLEGNTQLNEASCND 564
           +S  ++ S L Q EE  Q+T    N L +  + K D   L+   RN+  N+      C D
Sbjct: 349 YSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNI--NSHFANKKCQD 406

Query: 565 FLFERKSIVSLMPED--QISPVSEVLKPKQGTALLLPSPEFDYRPESEKVIQTSHDDIPL 622
            +   +++++    +  +I P S++  P+      LP+P+ D + E +KV  T + ++  
Sbjct: 407 VIVAARNLMTSEIHNTVKIIPDSKINVPE------LPTPDEDNKLEVQKVSNTQYHEVMN 460

Query: 623 LDEQS 627
           L+ ++
Sbjct: 461 LEPEN 465


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 37.0 bits (84), Expect = 0.21
 Identities = 177/904 (19%), Positives = 316/904 (34%), Gaps = 140/904 (15%)

Query: 41   EPSVIPDVKPGASSSLLSQNRALPLELQRTHVESCCEETYETLDHGSEPGRCGLVDSTA- 99
            EP+ + + K  +   L S++ A P+  +    ES   ++    D           D T  
Sbjct: 928  EPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKR 987

Query: 100  --GGSVASGILDRAKRSESMEPKVF----RDPGGQAGIIREPSEGAKEDPHQHSTAAE-- 151
               GS  S   +  K ++  + KV     R P  +  I +   E  K D  + S++++  
Sbjct: 988  KNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKD 1047

Query: 152  EKTSPSQEDLLMQSSKELSHVDLPEDFLRSKEGNVQITAETLLKSAEVQGMKVNGTKTDN 211
            EK + +      +S+KE       ++    K+ +  + +E L    E         K  +
Sbjct: 1048 EKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLD 1107

Query: 212  NEGHKNGNVSKDLSAGCGEFQEVDKIMTSDEVSETSTLVTPEPLTFVDPVLTEATPKEKE 271
            N+G K    +++      +F+     ++  EV+E   +V P P   ++P  TE   +  E
Sbjct: 1108 NKGEKRKRKTEEKGVD-KDFESSSMKISKLEVTE---IVKPSPKRKMEPD-TEKMDRTPE 1162

Query: 272  CEELKSCPWLSLPGNSAISNVDNGKEELCKPNLVCEADDNHQQLHGHHNEQPSSTHDSPT 331
             +++     LS P      N + GK+     N+              + ++PS   +S +
Sbjct: 1163 KDKIS----LSAPAKKIKLNRETGKKIGSTENI-------------SNTKEPSEKLESTS 1205

Query: 332  A-TSPLKENSEVSCFTSDLSGPESRTISLENCGFEGGGLLKRSAEKTDSSYF-------Y 383
            +     K   +V    +   G  S  +   +    GG  +++S EKTD+          Y
Sbjct: 1206 SKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEY 1265

Query: 384  RGDDQG-----------------KNLASREENEERLLIPRSERGGP--FLFN-------- 416
              D+                   K+    EE + +   P S  G P   + N        
Sbjct: 1266 NNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNI 1325

Query: 417  AREPEKEISGRCSGEKEPVVSPKENIHNNCIQDSLHTGNSSSLMPNSFTEATE--VMLNK 474
             + PEKE     S   E +    +++ +  IQ  + +  +S+      T+  +  V+  +
Sbjct: 1326 VKYPEKE-----SEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKE 1380

Query: 475  NDLKITVHVQGNLTNPEDHKETFTNMSHPGGHSEESSFSSLMQIEEAGQTTPVEPNILSK 534
            N  K     Q    +  D      N       S+E+  S       A       PN   K
Sbjct: 1381 NPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK 1440

Query: 535  SFYTKDCNSLVSIQRNLEGNTQLNEASCNDFLFERKSIVSLMPEDQISPVSEVLKPKQGT 594
            + Y  D     S +R  E N         D     K   S     +  P  E   PK+GT
Sbjct: 1441 TDY--DTREYSSSKRRDEKNELTRR---KDSPSRNKDSAS---GQKNKPREERDLPKKGT 1492

Query: 595  A---LLLPSPEFDYRPESEKVI---------QTSHDDIPLLDEQSIACEM--NELSCTNE 640
                    SP  D +P   K             S D  P  D +    E   N+ S  N+
Sbjct: 1493 GDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNK 1552

Query: 641  L--VVNKVESECVLNQQVSLNSQEHANLPTDSLLH---LNKEMPLATGRDAHQSHHPPLE 695
            L  ++N  E++ V  +Q++    +    P   L H   L+ ++   T   A +  +   +
Sbjct: 1553 LLYILNPPETQ-VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESD 1611

Query: 696  GRADVIADIQTIPIQTKIKDISPPGNQTCGASSNCPTLNIKPVSLERKKEMADSGTKALH 755
              ++V            +K+    GN          + ++K   +E+ KE  D+      
Sbjct: 1612 SESNV-----------SVKEEESSGN---------ISKDLKDKIVEKAKESLDT------ 1645

Query: 756  SRLRSNKREAAGFPQVVSVIECHSVQSQDISSCHRVRKNVSQENMCSASAAFK--SSKIS 813
                     AA     +S  + HS  S   S  H    + ++ +  SAS+A    S K  
Sbjct: 1646 ---------AAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKK 1696

Query: 814  LQVDNSLITKYENAFQHRDHCCQGTGHSVEKSSCKVSYTSQERELDGKETNGSLPGDKIR 873
             + +     K++   +H+ H   GT   +EKS        + ++   KE        K++
Sbjct: 1697 KKKEKKKHKKHKKHKKHKKHA--GTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1754

Query: 874  NKMV 877
            +  V
Sbjct: 1755 SVTV 1758


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 37.0 bits (84), Expect = 0.21
 Identities = 177/904 (19%), Positives = 316/904 (34%), Gaps = 140/904 (15%)

Query: 41   EPSVIPDVKPGASSSLLSQNRALPLELQRTHVESCCEETYETLDHGSEPGRCGLVDSTA- 99
            EP+ + + K  +   L S++ A P+  +    ES   ++    D           D T  
Sbjct: 962  EPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKR 1021

Query: 100  --GGSVASGILDRAKRSESMEPKVF----RDPGGQAGIIREPSEGAKEDPHQHSTAAE-- 151
               GS  S   +  K ++  + KV     R P  +  I +   E  K D  + S++++  
Sbjct: 1022 KNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKD 1081

Query: 152  EKTSPSQEDLLMQSSKELSHVDLPEDFLRSKEGNVQITAETLLKSAEVQGMKVNGTKTDN 211
            EK + +      +S+KE       ++    K+ +  + +E L    E         K  +
Sbjct: 1082 EKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLD 1141

Query: 212  NEGHKNGNVSKDLSAGCGEFQEVDKIMTSDEVSETSTLVTPEPLTFVDPVLTEATPKEKE 271
            N+G K    +++      +F+     ++  EV+E   +V P P   ++P  TE   +  E
Sbjct: 1142 NKGEKRKRKTEEKGVD-KDFESSSMKISKLEVTE---IVKPSPKRKMEPD-TEKMDRTPE 1196

Query: 272  CEELKSCPWLSLPGNSAISNVDNGKEELCKPNLVCEADDNHQQLHGHHNEQPSSTHDSPT 331
             +++     LS P      N + GK+     N+              + ++PS   +S +
Sbjct: 1197 KDKIS----LSAPAKKIKLNRETGKKIGSTENI-------------SNTKEPSEKLESTS 1239

Query: 332  A-TSPLKENSEVSCFTSDLSGPESRTISLENCGFEGGGLLKRSAEKTDSSYF-------Y 383
            +     K   +V    +   G  S  +   +    GG  +++S EKTD+          Y
Sbjct: 1240 SKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEY 1299

Query: 384  RGDDQG-----------------KNLASREENEERLLIPRSERGGP--FLFN-------- 416
              D+                   K+    EE + +   P S  G P   + N        
Sbjct: 1300 NNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNI 1359

Query: 417  AREPEKEISGRCSGEKEPVVSPKENIHNNCIQDSLHTGNSSSLMPNSFTEATE--VMLNK 474
             + PEKE     S   E +    +++ +  IQ  + +  +S+      T+  +  V+  +
Sbjct: 1360 VKYPEKE-----SEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKE 1414

Query: 475  NDLKITVHVQGNLTNPEDHKETFTNMSHPGGHSEESSFSSLMQIEEAGQTTPVEPNILSK 534
            N  K     Q    +  D      N       S+E+  S       A       PN   K
Sbjct: 1415 NPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKK 1474

Query: 535  SFYTKDCNSLVSIQRNLEGNTQLNEASCNDFLFERKSIVSLMPEDQISPVSEVLKPKQGT 594
            + Y  D     S +R  E N         D     K   S     +  P  E   PK+GT
Sbjct: 1475 TDY--DTREYSSSKRRDEKNELTRR---KDSPSRNKDSAS---GQKNKPREERDLPKKGT 1526

Query: 595  A---LLLPSPEFDYRPESEKVI---------QTSHDDIPLLDEQSIACEM--NELSCTNE 640
                    SP  D +P   K             S D  P  D +    E   N+ S  N+
Sbjct: 1527 GDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNK 1586

Query: 641  L--VVNKVESECVLNQQVSLNSQEHANLPTDSLLH---LNKEMPLATGRDAHQSHHPPLE 695
            L  ++N  E++ V  +Q++    +    P   L H   L+ ++   T   A +  +   +
Sbjct: 1587 LLYILNPPETQ-VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESD 1645

Query: 696  GRADVIADIQTIPIQTKIKDISPPGNQTCGASSNCPTLNIKPVSLERKKEMADSGTKALH 755
              ++V            +K+    GN          + ++K   +E+ KE  D+      
Sbjct: 1646 SESNV-----------SVKEEESSGN---------ISKDLKDKIVEKAKESLDT------ 1679

Query: 756  SRLRSNKREAAGFPQVVSVIECHSVQSQDISSCHRVRKNVSQENMCSASAAFK--SSKIS 813
                     AA     +S  + HS  S   S  H    + ++ +  SAS+A    S K  
Sbjct: 1680 ---------AAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKK 1730

Query: 814  LQVDNSLITKYENAFQHRDHCCQGTGHSVEKSSCKVSYTSQERELDGKETNGSLPGDKIR 873
             + +     K++   +H+ H   GT   +EKS        + ++   KE        K++
Sbjct: 1731 KKKEKKKHKKHKKHKKHKKHA--GTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1788

Query: 874  NKMV 877
            +  V
Sbjct: 1789 SVTV 1792


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 37.0 bits (84), Expect = 0.21
 Identities = 43/166 (25%), Positives = 66/166 (39%), Gaps = 21/166 (12%)

Query: 1885 LSIWSQHGPSVCSFEISSLHSPHCKRQPSLGTTSSHTMLPYVPLPGMEATYNTSGSQTRL 1944
            L I SQ  PS  +   S   SP  + QP+   TS+    P  PLP      + S ++ RL
Sbjct: 1258 LPICSQPQPSTEATVPSPTQSP-IRFQPAPAKTST----PLAPLP----VQSQSDTKDRL 1308

Query: 1945 EPPFPALVPKSCLVAESAVSKLLLSASEFQ----VRGLDELDGVKAACPCPQSSPPEQKE 2000
              P   L     L     V +  + ++E +    +  +D   G + + P P   P   K 
Sbjct: 1309 GSP---LAVDEALRRSDLVEEFWMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKS 1365

Query: 2001 AEPEKRPKK-----VSQIRIRKTIPRPDPNLTPMGLPRPKRLKKKE 2041
               EK P+      +  + I K +  P P   P+ LP P+    +E
Sbjct: 1366 YSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLSLPTPRSPSDRE 1411


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 36.6 bits (83), Expect = 0.27
 Identities = 26/116 (22%), Positives = 50/116 (43%)

Query: 1983 GVKAACPCPQSSPPEQKEAEPEKRPKKVSQIRIRKTIPRPDPNLTPMGLPRPKRLKKKEF 2042
            G +AA   P   PP ++ +        V+   +  ++P P  N TP+G  +  R ++KE 
Sbjct: 669  GSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKETRKQEKER 728

Query: 2043 SLEEIYTNKNYKSPPANRCLETIFEEPKERNGTLISISQQKRKRVLEFQDFTVPRK 2098
              +E    K  K     R  +    E +E+        +QK+++  + +  ++ RK
Sbjct: 729  QKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRK 784


>gi|148612831 kinesin family member 18A [Homo sapiens]
          Length = 898

 Score = 36.6 bits (83), Expect = 0.27
 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 23/148 (15%)

Query: 784 DISSCHRVRKNVSQENMCSASAA---FKSSKISLQVDNSLITKYENAFQHRDHCCQGTGH 840
           +++  H  RK   QE++ S        KSSK  L    SL    ++  Q  D     T H
Sbjct: 750 EVAIPHNRRKECGQEDLDSTFTICEDIKSSKCKLPEQESLPNDNKDILQRLDPSSFSTKH 809

Query: 841 SVEKSSCKVSY------TSQERELDGKETNGSLPGDKIRNKMVAGLLNSGISNKTIHTSS 894
           S+   S   SY        ++R+L    +N SL  D          +NSG + +    +S
Sbjct: 810 SMPVPSMVPSYMAMTTAAKRKRKLTSSTSNSSLTAD----------VNSGFAKRVRQDNS 859

Query: 895 SIKLSEEGLEGKEQDVSKETVFCKYNIS 922
               SE+ L+  +  +  +   CK N S
Sbjct: 860 ----SEKHLQENKPTMEHKRNICKINPS 883


>gi|139948432 adlican [Homo sapiens]
          Length = 2828

 Score = 36.2 bits (82), Expect = 0.36
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%)

Query: 465  TEATEVMLNKNDLKITVHVQGNLTNPEDHKETFTNMSHPGGHSEESSFSSLMQIEEAGQT 524
            ++A    L+++ L+ TV +  + T P++H  T   M  P   S  +   SL      GQT
Sbjct: 1453 SQAETTTLDQDHLETTVAILLSETRPQNHTPTAARMKEPASSSPSTILMSL------GQT 1506

Query: 525  TPVEPNILSKSFYTKDCNSLVSIQRNLEGNTQLNEASCND 564
            T  +P + S        +S  ++  N  GN +      N+
Sbjct: 1507 TTTKPALPSPRISQASRDSKENVFLNYVGNPETEATPVNN 1546


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 35.4 bits (80), Expect = 0.61
 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 9/82 (10%)

Query: 1993  SSPPEQKEAEPEKRPKKVSQIRIRKTIPRP---DPNLTPMGLPRPKRLKKKEFSLEEIYT 2049
             ++PP++ E  P K P+   ++   K +P P    P + P  +P   ++   E  + E   
Sbjct: 10596 AAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP 10655

Query: 2050  NKNYKSPPANRCLETIFEEPKE 2071
              K    PP       +FEEP+E
Sbjct: 10656 PKPESPPP------EVFEEPEE 10671


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score = 35.4 bits (80), Expect = 0.61
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 8/75 (10%)

Query: 114 SESMEPKVFRDPGGQAGIIREPSEGAKEDPHQ-----HSTAAEEKTSPSQEDLLMQSSKE 168
           S  +EP+  + PGG +   R+  +G++E+P         +AA +  S S ED+   SS +
Sbjct: 466 SHCVEPEPSQVPGGSS---RDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQ 522

Query: 169 LSHVDLPEDFLRSKE 183
               + PE+ +RS E
Sbjct: 523 AKVDNQPEELVRSAE 537


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score = 35.4 bits (80), Expect = 0.61
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 8/75 (10%)

Query: 114 SESMEPKVFRDPGGQAGIIREPSEGAKEDPHQ-----HSTAAEEKTSPSQEDLLMQSSKE 168
           S  +EP+  + PGG +   R+  +G++E+P         +AA +  S S ED+   SS +
Sbjct: 467 SHCVEPEPSQVPGGSS---RDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQ 523

Query: 169 LSHVDLPEDFLRSKE 183
               + PE+ +RS E
Sbjct: 524 AKVDNQPEELVRSAE 538


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score = 35.4 bits (80), Expect = 0.61
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 8/75 (10%)

Query: 114 SESMEPKVFRDPGGQAGIIREPSEGAKEDPHQ-----HSTAAEEKTSPSQEDLLMQSSKE 168
           S  +EP+  + PGG +   R+  +G++E+P         +AA +  S S ED+   SS +
Sbjct: 466 SHCVEPEPSQVPGGSS---RDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQ 522

Query: 169 LSHVDLPEDFLRSKE 183
               + PE+ +RS E
Sbjct: 523 AKVDNQPEELVRSAE 537


>gi|110349797 homer 2 isoform 4 [Homo sapiens]
          Length = 299

 Score = 35.4 bits (80), Expect = 0.61
 Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 27/170 (15%)

Query: 1191 RETQEMTEGSRL-----EPNSEFGKESTFGISSKESM-------SCHDESSVSLRSLKSI 1238
            RET   T+ S +     E  S  G  +T   S  + +       + + ++ ++    K+ 
Sbjct: 133  RETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKNEINREKEKNT 192

Query: 1239 EIMPSQENSETNVNSEETDLKNLCKPKDGEMLCENVKDCTVLPEMKEIVSRDWSNSSDR- 1297
            ++    E  E  +  +ET+LK+L   K  E++ + + +C  + E  E   RD  N  D+ 
Sbjct: 193  QLKRRIEELEAELREKETELKDL--RKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKV 250

Query: 1298 DSVCTCVEKNACKACHPHENSSDRHLPLTVKTDIKV---KGEETEEHQRG 1344
             S+ T +E++  +          RHL + +K+ ++V   K ++  + +RG
Sbjct: 251  RSLKTDIEESKYR---------QRHLKVELKSFLEVLDGKIDDLHDFRRG 291


>gi|109637791 transcription factor-like nuclear regulator [Homo
           sapiens]
          Length = 2624

 Score = 35.4 bits (80), Expect = 0.61
 Identities = 68/318 (21%), Positives = 114/318 (35%), Gaps = 63/318 (19%)

Query: 110 RAKRSESMEPKVFRDPGGQAGIIREPSEGAKEDPHQHSTAAEEKTSPSQEDL-------L 162
           ++ ++ S++ K    P     + +   EG   DP +  ++    T  SQ+D        L
Sbjct: 384 KSVKNHSLKEKKSTKPRKNVKVKKVACEGVNNDPDESMSSRISDTERSQKDAQTVEEESL 443

Query: 163 MQSSKELSHVDLPEDFLRSK------EGNVQITAETLLKSAEVQGMKVNGTKTDN----- 211
             S ++   V L  D  + K      +G  ++    LL++A VQ     G K  N     
Sbjct: 444 TLSREDAEQVALEVDLNQKKRRRKKQDGANELGVNNLLENATVQAGPSKGEKHKNKCQAI 503

Query: 212 NEGHKNGNVSKDLSAGCGE-------FQEVDKI-----------------MTSDEVSETS 247
               K G  SK+    C +       F   +K+                   + E SE+S
Sbjct: 504 RPELKEGECSKEQMLSCTQNIDGIVGFASTEKVEKRTDPILSLSNQQDATSVATESSESS 563

Query: 248 TLVTPEPLTFVDPVLTEATPKEKECEELKSCPWLSLPGNS-AISNVDN------GKEELC 300
           T   P     +   L E    E  C E ++   + L  NS  I   +N      G+ +  
Sbjct: 564 TSDLPSFEVGI-RALCEVNNAEGSCIEERN---VDLKNNSLEIDQTENVKPMLRGRFQRP 619

Query: 301 KPNLVCEADDNHQQLHGHHNEQPSSTHDSPTATSPLKENSEVSCF------TSDLSGPES 354
           KPNL   A        G    +  ++H   +      E  +++        T++   PE+
Sbjct: 620 KPNL-SRAGKKSVLSQGKTESESKNSHSKTSVEKNHVEKDKMNTLDILRMETTERENPEA 678

Query: 355 RTISL---ENCGFEGGGL 369
            T+S+   +NC  EG  L
Sbjct: 679 ETVSVLGEKNCLQEGSQL 696


>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
           sapiens]
          Length = 1134

 Score = 35.0 bits (79), Expect = 0.79
 Identities = 47/181 (25%), Positives = 66/181 (36%), Gaps = 25/181 (13%)

Query: 431 EKEPVVSPKENIHNNCIQDSLHTGNSSSLMPNSFTEATEVMLNKNDLKITVHVQGNLTNP 490
           E EPV S +EN  N  I   L        + N +   ++  L     K++     N   P
Sbjct: 683 ETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLS-----NAPRP 737

Query: 491 EDHKETFTNMSHPGGHSEESSFSSLMQIEEAGQTTPVEPNILSKSF-YTKDCNSLVSIQR 549
              + + T    P G + +        I  A   T   P+  SKS   T    S V IQ 
Sbjct: 738 LKKRSSITEPEGPNGPNIQKLLYQRTTI--AAMETISVPSYPSKSASVTASSESPVEIQ- 794

Query: 550 NLEGNTQLNEASCNDFLF--ERKSIVSLMPEDQISPVSEVLKPKQGTALLLPSPEFDYRP 607
                        N +L     K +VSL+PE  +SP        + + +  PSP  DY P
Sbjct: 795 -------------NPYLHVEPEKEVVSLVPES-LSPEDVGNASTENSDMPAPSPGLDYEP 840

Query: 608 E 608
           E
Sbjct: 841 E 841


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,092,130
Number of Sequences: 37866
Number of extensions: 4363435
Number of successful extensions: 12197
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 126
Number of HSP's that attempted gapping in prelim test: 11918
Number of HSP's gapped (non-prelim): 432
length of query: 2151
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2033
effective length of database: 13,779,330
effective search space: 28013377890
effective search space used: 28013377890
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press