Guide to the Human Genome
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Search of human proteins with 209915561

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209915561 dynamin 3 isoform b [Homo sapiens]
         (859 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209915561 dynamin 3 isoform b [Homo sapiens]                      1708   0.0  
gi|42544243 dynamin 3 isoform a [Homo sapiens]                       1702   0.0  
gi|56549119 dynamin 2 isoform 3 [Homo sapiens]                       1382   0.0  
gi|56549125 dynamin 2 isoform 4 [Homo sapiens]                       1377   0.0  
gi|56549121 dynamin 2 isoform 1 [Homo sapiens]                       1376   0.0  
gi|56549123 dynamin 2 isoform 2 [Homo sapiens]                       1372   0.0  
gi|59853099 dynamin 1 isoform 1 [Homo sapiens]                       1355   0.0  
gi|56549117 dynamin 1 isoform 2 [Homo sapiens]                       1342   0.0  
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]                  438   e-122
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]                  437   e-122
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]                  437   e-122
gi|222136619 myxovirus resistance protein 1 [Homo sapiens]            230   4e-60
gi|222136617 myxovirus resistance protein 1 [Homo sapiens]            230   4e-60
gi|11342664 myxovirus resistance protein 2 [Homo sapiens]             219   9e-57
gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]         117   5e-26
gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]         117   5e-26
gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]         117   5e-26
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]                 103   7e-22
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]                 103   7e-22
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]                  103   7e-22
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]                 103   7e-22
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]                  103   7e-22
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]                  103   7e-22
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]                  103   7e-22
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]                 103   7e-22
gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens]            92   2e-18
gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo ...    86   1e-16
gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo ...    86   1e-16
gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo ...    86   2e-16
gi|153792074 proline rich 12 [Homo sapiens]                            62   2e-09

>gi|209915561 dynamin 3 isoform b [Homo sapiens]
          Length = 859

 Score = 1708 bits (4423), Expect = 0.0
 Identities = 859/859 (100%), Positives = 859/859 (100%)

Query: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
           SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI
Sbjct: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240

Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
           DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300

Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
           QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
           KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
           KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480

Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
           IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540

Query: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
           LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE
Sbjct: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600

Query: 601 LACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYM 660
           LACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYM
Sbjct: 601 LACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYM 660

Query: 661 SIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLR 720
           SIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLR
Sbjct: 661 SIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLR 720

Query: 721 MYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPT 780
           MYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPT
Sbjct: 721 MYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPT 780

Query: 781 SGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVPSRRP 840
           SGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVPSRRP
Sbjct: 781 SGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVPSRRP 840

Query: 841 PPSPTRPTIIRPLESSLLD 859
           PPSPTRPTIIRPLESSLLD
Sbjct: 841 PPSPTRPTIIRPLESSLLD 859


>gi|42544243 dynamin 3 isoform a [Homo sapiens]
          Length = 863

 Score = 1702 bits (4408), Expect = 0.0
 Identities = 859/863 (99%), Positives = 859/863 (99%), Gaps = 4/863 (0%)

Query: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
           SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI
Sbjct: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240

Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
           DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300

Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
           QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
           KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
           KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480

Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
           IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540

Query: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
           LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE
Sbjct: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600

Query: 601 LACDSQEDVDSWKASLLRAGVYPDKSV----AENDENGQAENFSMDPQLERQVETIRNLV 656
           LACDSQEDVDSWKASLLRAGVYPDKSV    AENDENGQAENFSMDPQLERQVETIRNLV
Sbjct: 601 LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV 660

Query: 657 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 716
           DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD
Sbjct: 661 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 720

Query: 717 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL 776
           EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL
Sbjct: 721 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL 780

Query: 777 ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP 836
           ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP
Sbjct: 781 ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP 840

Query: 837 SRRPPPSPTRPTIIRPLESSLLD 859
           SRRPPPSPTRPTIIRPLESSLLD
Sbjct: 841 SRRPPPSPTRPTIIRPLESSLLD 863


>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
          Length = 866

 Score = 1382 bits (3576), Expect = 0.0
 Identities = 697/870 (80%), Positives = 772/870 (88%), Gaps = 15/870 (1%)

Query: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
           SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
           DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP  R+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
           Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
           +INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPD+AFEAIVKKQ+VKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420

Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
           K P LK VDLVIQELINTV++CT KL+++PRL EETERIV  +IREREG+TKDQ+LLLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
           I+ SYINTNHEDFIGFANAQQRS+Q++KK  + NQVIR+GWLTI+NI +MKGGSK YWFV
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540

Query: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
           LTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD R +E
Sbjct: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600

Query: 601 LACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYM 660
           LACDSQEDVDSWKAS LRAGVYP+K  AEN++  Q   FSMDPQLERQVETIRNLVDSY+
Sbjct: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660

Query: 661 SIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLR 720
           +IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD+MLR
Sbjct: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720

Query: 721 MYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-PLARP 779
           MY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q +      SPT QRRP  S  P  RP
Sbjct: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHPPGRP 777

Query: 780 TSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTR--- 830
            + RGP P    IP P        APP+P RPGP   F ++SD F APPQ+PSRP R   
Sbjct: 778 PAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPVRIPP 836

Query: 831 -APPSVPSRRPPPSPTRPTIIRPLESSLLD 859
             PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 837 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866


>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
          Length = 866

 Score = 1377 bits (3565), Expect = 0.0
 Identities = 695/870 (79%), Positives = 769/870 (88%), Gaps = 15/870 (1%)

Query: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
           SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
           DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP  R+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
           Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
           +INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
           K PSLK VDLV+ EL   +KKC +KL+++PRL EETERIV  +IREREG+TKDQ+LLLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
           I+ SYINTNHEDFIGFANAQQRS+Q++KK  + NQVIR+GWLTI+NI +MKGGSK YWFV
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540

Query: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
           LTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD R +E
Sbjct: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600

Query: 601 LACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYM 660
           LACDSQEDVDSWKAS LRAGVYP+K  AEN++  Q   FSMDPQLERQVETIRNLVDSY+
Sbjct: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660

Query: 661 SIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLR 720
           +IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD+MLR
Sbjct: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720

Query: 721 MYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-PLARP 779
           MY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q +      SPT QRRP  S  P  RP
Sbjct: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHPPGRP 777

Query: 780 TSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTR--- 830
            + RGP P    IP P        APP+P RPGP   F ++SD F APPQ+PSRP R   
Sbjct: 778 PAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPVRIPP 836

Query: 831 -APPSVPSRRPPPSPTRPTIIRPLESSLLD 859
             PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 837 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866


>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
          Length = 870

 Score = 1376 bits (3561), Expect = 0.0
 Identities = 697/874 (79%), Positives = 772/874 (88%), Gaps = 19/874 (2%)

Query: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
           SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
           DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP  R+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
           Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
           +INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPD+AFEAIVKKQ+VKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420

Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
           K P LK VDLVIQELINTV++CT KL+++PRL EETERIV  +IREREG+TKDQ+LLLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536
           I+ SYINTNHEDFIGFANAQQRS+Q++KK  + NQ    VIR+GWLTI+NI +MKGGSK 
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540

Query: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596
           YWFVLTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD 
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600

Query: 597 RFLELACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLV 656
           R +ELACDSQEDVDSWKAS LRAGVYP+K  AEN++  Q   FSMDPQLERQVETIRNLV
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 660

Query: 657 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 716
           DSY++IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD
Sbjct: 661 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 720

Query: 717 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-P 775
           +MLRMY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q +      SPT QRRP  S  P
Sbjct: 721 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHP 777

Query: 776 LARPTSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPT 829
             RP + RGP P    IP P        APP+P RPGP   F ++SD F APPQ+PSRP 
Sbjct: 778 PGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPV 836

Query: 830 R----APPSVPSRRPPPSPTRPTIIRPLESSLLD 859
           R     PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 837 RIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 870


>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
          Length = 870

 Score = 1372 bits (3550), Expect = 0.0
 Identities = 695/874 (79%), Positives = 769/874 (87%), Gaps = 19/874 (2%)

Query: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
           SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
           DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP  R+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
           Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
           +INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
           K PSLK VDLV+ EL   +KKC +KL+++PRL EETERIV  +IREREG+TKDQ+LLLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536
           I+ SYINTNHEDFIGFANAQQRS+Q++KK  + NQ    VIR+GWLTI+NI +MKGGSK 
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540

Query: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596
           YWFVLTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD 
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600

Query: 597 RFLELACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLV 656
           R +ELACDSQEDVDSWKAS LRAGVYP+K  AEN++  Q   FSMDPQLERQVETIRNLV
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 660

Query: 657 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 716
           DSY++IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD
Sbjct: 661 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 720

Query: 717 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-P 775
           +MLRMY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q +      SPT QRRP  S  P
Sbjct: 721 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHP 777

Query: 776 LARPTSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPT 829
             RP + RGP P    IP P        APP+P RPGP   F ++SD F APPQ+PSRP 
Sbjct: 778 PGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPV 836

Query: 830 R----APPSVPSRRPPPSPTRPTIIRPLESSLLD 859
           R     PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 837 RIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 870


>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
          Length = 864

 Score = 1355 bits (3507), Expect = 0.0
 Identities = 693/869 (79%), Positives = 763/869 (87%), Gaps = 26/869 (2%)

Query: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR ME+LIPLVNRLQDAFSA+GQ+  L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
           SGIVTRRPLVLQLV +  EYAEFLHCKGKKFTDF+EVRLEIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QIR+M+MQF+T+ENCLILAV+PAN+D
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
           DIDGKKDI AA+ AERKFFLSHP+YRH+ADRMGTP+LQKVLNQQLTNHIRDTLP  RNKL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300

Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
           Q QLLSIE EVE YKNF+P+DP RKTKALLQMVQQFAVDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360

Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
           +INRIFHERFPFE+VKMEF+EKELRREISYAIKNIHGIRTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420

Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
           + P LK VD+VI ELI+TV++CTKKL  +PRL EE ERIV  HIREREG+TK+QV+LLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480

Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536
           I+++Y+NTNHEDFIGFANAQQRS+Q++KK T GNQ    VIRKGWLTI+NIGIMKGGSK 
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540

Query: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596
           YWFVLTAE+LSWYKDDEEKEKKYML +DNLK+RDVEK FMSSKHIFALFNTEQRNVYKDY
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600

Query: 597 RFLELACDSQEDVDSWKASLLRAGVYPDK-----SVAENDENGQAENF--SMDPQLERQV 649
           R LELAC++QE+VDSWKAS LRAGVYP++       +E +ENG +++F  SMDPQLERQV
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENG-SDSFMHSMDPQLERQV 659

Query: 650 ETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESA 709
           ETIRNLVDSYM+I+NK +RDL+PKTIMHLMINN K+FI SELLA LYS  DQNTLMEESA
Sbjct: 660 ETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESA 719

Query: 710 EQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ-----HSRRSPPPSP 764
           EQAQRRDEMLRMY ALKEAL IIGDI+T TVSTP PPPVDDSW+Q       RRSP  SP
Sbjct: 720 EQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSP 779

Query: 765 TTQRRPTLSAPLARPTSGRGPAPAIPSPGPH-SGAPPVPFRPGPLPPFPSSSDSFGAPPQ 823
           T QRR   + P ARP S RGPAP  P  G    GAPPVP RPG      +S D FG PPQ
Sbjct: 780 TPQRRAP-AVPPARPGS-RGPAPGPPPAGSALGGAPPVPSRPG------ASPDPFGPPPQ 831

Query: 824 VPSRPTRAPPSVPSRRPPPSPTRPTIIRP 852
           VPSRP RAPP VPSR    SP+RP   RP
Sbjct: 832 VPSRPNRAPPGVPSRSGQASPSRPESPRP 860


>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
          Length = 851

 Score = 1342 bits (3473), Expect = 0.0
 Identities = 685/853 (80%), Positives = 754/853 (88%), Gaps = 26/853 (3%)

Query: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR ME+LIPLVNRLQDAFSA+GQ+  L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
           SGIVTRRPLVLQLV +  EYAEFLHCKGKKFTDF+EVRLEIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QIR+M+MQF+T+ENCLILAV+PAN+D
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
           DIDGKKDI AA+ AERKFFLSHP+YRH+ADRMGTP+LQKVLNQQLTNHIRDTLP  RNKL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300

Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
           Q QLLSIE EVE YKNF+P+DP RKTKALLQMVQQFAVDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360

Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
           +INRIFHERFPFE+VKMEF+EKELRREISYAIKNIHGIRTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420

Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
           + P LK VD+VI ELI+TV++CTKKL  +PRL EE ERIV  HIREREG+TK+QV+LLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480

Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536
           I+++Y+NTNHEDFIGFANAQQRS+Q++KK T GNQ    VIRKGWLTI+NIGIMKGGSK 
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540

Query: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596
           YWFVLTAE+LSWYKDDEEKEKKYML +DNLK+RDVEK FMSSKHIFALFNTEQRNVYKDY
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600

Query: 597 RFLELACDSQEDVDSWKASLLRAGVYPDK-----SVAENDENGQAENF--SMDPQLERQV 649
           R LELAC++QE+VDSWKAS LRAGVYP++       +E +ENG +++F  SMDPQLERQV
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENG-SDSFMHSMDPQLERQV 659

Query: 650 ETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESA 709
           ETIRNLVDSYM+I+NK +RDL+PKTIMHLMINN K+FI SELLA LYS  DQNTLMEESA
Sbjct: 660 ETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESA 719

Query: 710 EQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ-----HSRRSPPPSP 764
           EQAQRRDEMLRMY ALKEAL IIGDI+T TVSTP PPPVDDSW+Q       RRSP  SP
Sbjct: 720 EQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSP 779

Query: 765 TTQRRPTLSAPLARPTSGRGPAPAIPSPGPH-SGAPPVPFRPGPLPPFPSSSDSFGAPPQ 823
           T QRR   + P ARP S RGPAP  P  G    GAPPVP RPG      +S D FG PPQ
Sbjct: 780 TPQRRAP-AVPPARPGS-RGPAPGPPPAGSALGGAPPVPSRPG------ASPDPFGPPPQ 831

Query: 824 VPSRPTRAPPSVP 836
           VPSRP RAPP VP
Sbjct: 832 VPSRPNRAPPGVP 844


>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
          Length = 699

 Score =  438 bits (1126), Expect = e-122
 Identities = 243/548 (44%), Positives = 356/548 (64%), Gaps = 31/548 (5%)

Query: 6   MEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++N+LQD F+ +G   +++LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGAD-IIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLVLQLV----------------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVT 109
           RRPL+LQLV                    E+ +FLH K K +TDFDE+R EIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENC 169
           G NKG+S  PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QIRE+I++FI+  N 
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAVT ANTD+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHI 289
           G +GVVNRSQ DI+ KK +  ++  E  F      Y  +A+R GT +L + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGD 349
           RD LP  + ++   +L+ +++       +P D   K+  LLQ++ +FA ++   IEG+  
Sbjct: 298 RDCLPELKTRI--NVLAAQYQSLLNSYGEPVDD--KSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAF 409
            ++T EL GGA+I  IFHE F   +  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 EAIVKKQIVKLKGPSLKSVDLVIQELINTVKKC----TKKLANFPRLCEETERIVANHIR 465
           E +VK+QI +L+ PSL+ V+LV +E+   ++ C    T++L  FP+L +    +V   +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTIS 525
           +R   T + V  L+ I+++YINT H DF         + +  ++    N++ R+    +S
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRR----NRLARELPSAVS 529

Query: 526 NIGIMKGG 533
              +  GG
Sbjct: 530 RDKVASGG 537



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 40/90 (44%), Positives = 57/90 (63%)

Query: 646 ERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLM 705
           +R  E I  L+ SY  I+ K I+D +PK +MH ++N+VKD + SEL+ QLY S   + L+
Sbjct: 604 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 663

Query: 706 EESAEQAQRRDEMLRMYQALKEALGIIGDI 735
            ES + AQRR E   M +AL+ A  II +I
Sbjct: 664 TESEDMAQRRKEAADMLKALQGASQIIAEI 693


>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
          Length = 736

 Score =  437 bits (1125), Expect = e-122
 Identities = 238/531 (44%), Positives = 349/531 (65%), Gaps = 27/531 (5%)

Query: 6   MEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++N+LQD F+ +G   +++LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGAD-IIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLVLQLV----------------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVT 109
           RRPL+LQLV                    E+ +FLH K K +TDFDE+R EIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENC 169
           G NKG+S  PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QIRE+I++FI+  N 
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAVT ANTD+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHI 289
           G +GVVNRSQ DI+ KK +  ++  E  F      Y  +A+R GT +L + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGD 349
           RD LP  + ++   +L+ +++       +P D   K+  LLQ++ +FA ++   IEG+  
Sbjct: 298 RDCLPELKTRI--NVLAAQYQSLLNSYGEPVDD--KSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAF 409
            ++T EL GGA+I  IFHE F   +  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 EAIVKKQIVKLKGPSLKSVDLVIQELINTVKKC----TKKLANFPRLCEETERIVANHIR 465
           E +VK+QI +L+ PSL+ V+LV +E+   ++ C    T++L  FP+L +    +V   +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQV 516
           +R   T + V  L+ I+++YINT H DF         + +  ++  +  ++
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLAREL 524



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 40/90 (44%), Positives = 57/90 (63%)

Query: 646 ERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLM 705
           +R  E I  L+ SY  I+ K I+D +PK +MH ++N+VKD + SEL+ QLY S   + L+
Sbjct: 641 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 700

Query: 706 EESAEQAQRRDEMLRMYQALKEALGIIGDI 735
            ES + AQRR E   M +AL+ A  II +I
Sbjct: 701 TESEDMAQRRKEAADMLKALQGASQIIAEI 730


>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
          Length = 710

 Score =  437 bits (1125), Expect = e-122
 Identities = 238/531 (44%), Positives = 349/531 (65%), Gaps = 27/531 (5%)

Query: 6   MEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++N+LQD F+ +G   +++LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGAD-IIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLVLQLV----------------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVT 109
           RRPL+LQLV                    E+ +FLH K K +TDFDE+R EIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENC 169
           G NKG+S  PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QIRE+I++FI+  N 
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAVT ANTD+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHI 289
           G +GVVNRSQ DI+ KK +  ++  E  F      Y  +A+R GT +L + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGD 349
           RD LP  + ++   +L+ +++       +P D   K+  LLQ++ +FA ++   IEG+  
Sbjct: 298 RDCLPELKTRI--NVLAAQYQSLLNSYGEPVDD--KSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAF 409
            ++T EL GGA+I  IFHE F   +  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 EAIVKKQIVKLKGPSLKSVDLVIQELINTVKKC----TKKLANFPRLCEETERIVANHIR 465
           E +VK+QI +L+ PSL+ V+LV +E+   ++ C    T++L  FP+L +    +V   +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQV 516
           +R   T + V  L+ I+++YINT H DF         + +  ++  +  ++
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLAREL 524



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 40/90 (44%), Positives = 57/90 (63%)

Query: 646 ERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLM 705
           +R  E I  L+ SY  I+ K I+D +PK +MH ++N+VKD + SEL+ QLY S   + L+
Sbjct: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674

Query: 706 EESAEQAQRRDEMLRMYQALKEALGIIGDI 735
            ES + AQRR E   M +AL+ A  II +I
Sbjct: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704


>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
          Length = 662

 Score =  230 bits (587), Expect = 4e-60
 Identities = 161/439 (36%), Positives = 240/439 (54%), Gaps = 23/439 (5%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTR 66
           E++ P ++ L D+  ALG    L LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR
Sbjct: 47  EKVRPCID-LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSG-VALPRGSGIVTR 104

Query: 67  RPLVLQLV--------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSI 118
            PLVL+L           K  Y ++      + +D  EV  EI    + + G   GIS  
Sbjct: 105 CPLVLKLKKLVNEDKWRGKVSYQDY----EIEISDASEVEKEINKAQNAIAGEGMGISHE 160

Query: 119 PINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPAN 178
            I L + S  V +LTLIDLPGIT+V VG+QP DI Y+I+ +I ++I R+  + L V P+N
Sbjct: 161 LITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSN 220

Query: 179 TDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYVGVVN 236
            D+A ++AL +A+EVDP+G RTIG++TK DL+D+GT+ +  DV+ N +  L++GY+ V  
Sbjct: 221 VDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKC 280

Query: 237 RSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIAD--RMGTPHLQKVLNQQLTNHIRDTLP 294
           R Q++I  +  +  A+  E+ FF +HP +R + +  +   P L + L  +L  HI  +LP
Sbjct: 281 RGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLP 340

Query: 295 NFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTL 354
              N+++     I  E++ Y    PED   K   L+  V  F  D    ++G  + V   
Sbjct: 341 LLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEE 399

Query: 355 ELSGGAKINRIFHERFPFEIVKMEFNE--KELRREISYAIKNIHGIRTGLFTPDMAFEAI 412
           ++    ++   FH+     I++  F E  K L R+I        G     F     FE I
Sbjct: 400 DIRLFTRLRHEFHKW--STIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETI 457

Query: 413 VKKQIVKLKGPSLKSVDLV 431
           VK+QI  L+ P++  +  V
Sbjct: 458 VKQQIKALEEPAVDMLHTV 476


>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
          Length = 662

 Score =  230 bits (587), Expect = 4e-60
 Identities = 161/439 (36%), Positives = 240/439 (54%), Gaps = 23/439 (5%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTR 66
           E++ P ++ L D+  ALG    L LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR
Sbjct: 47  EKVRPCID-LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSG-VALPRGSGIVTR 104

Query: 67  RPLVLQLV--------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSI 118
            PLVL+L           K  Y ++      + +D  EV  EI    + + G   GIS  
Sbjct: 105 CPLVLKLKKLVNEDKWRGKVSYQDY----EIEISDASEVEKEINKAQNAIAGEGMGISHE 160

Query: 119 PINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPAN 178
            I L + S  V +LTLIDLPGIT+V VG+QP DI Y+I+ +I ++I R+  + L V P+N
Sbjct: 161 LITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSN 220

Query: 179 TDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYVGVVN 236
            D+A ++AL +A+EVDP+G RTIG++TK DL+D+GT+ +  DV+ N +  L++GY+ V  
Sbjct: 221 VDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKC 280

Query: 237 RSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIAD--RMGTPHLQKVLNQQLTNHIRDTLP 294
           R Q++I  +  +  A+  E+ FF +HP +R + +  +   P L + L  +L  HI  +LP
Sbjct: 281 RGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLP 340

Query: 295 NFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTL 354
              N+++     I  E++ Y    PED   K   L+  V  F  D    ++G  + V   
Sbjct: 341 LLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEE 399

Query: 355 ELSGGAKINRIFHERFPFEIVKMEFNE--KELRREISYAIKNIHGIRTGLFTPDMAFEAI 412
           ++    ++   FH+     I++  F E  K L R+I        G     F     FE I
Sbjct: 400 DIRLFTRLRHEFHKW--STIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETI 457

Query: 413 VKKQIVKLKGPSLKSVDLV 431
           VK+QI  L+ P++  +  V
Sbjct: 458 VKQQIKALEEPAVDMLHTV 476


>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
          Length = 715

 Score =  219 bits (558), Expect = 9e-57
 Identities = 162/465 (34%), Positives = 237/465 (50%), Gaps = 14/465 (3%)

Query: 16  LQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVT 75
           L D+  ALG    L LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR PLVL+L  
Sbjct: 103 LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTRCPLVLKLKK 161

Query: 76  SKAE-YAEFLHCKGKKFT--DFDEVRLEIEAETDRVTGMNKGISSIPINLRVYSPHVLNL 132
              E +A  +  +  +    D  +V  EI    + + G  +GIS   I+L + SP V +L
Sbjct: 162 QPCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDL 221

Query: 133 TLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTDLANSDALKLAKE 192
           T+IDLPGIT+V V +QP DI  QI+ +I ++I R+  + L V P N D+A ++AL +A E
Sbjct: 222 TIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHE 281

Query: 193 VDPQGLRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKA 250
           VDP+G RTIG++TK DLMD GT+    +V+ N   PL++GY+ V  R Q++I  +  +  
Sbjct: 282 VDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSLAE 341

Query: 251 AMLAERKFFLSHPAYRHIADR--MGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIE 308
           A   E  FF +HP +R + +      P L + L  +L  HI+ +LP    +++       
Sbjct: 342 ATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRESHQKAT 401

Query: 309 HEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGAKINRIFHE 368
            E+       P     K   L++ ++ F  D EK +EG  + V   E     KI   F  
Sbjct: 402 EELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEGE-EVVRENETRLYNKIREDFKN 460

Query: 369 RFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSL--- 425
                    +  +  +  E+    K   G     F     FE IV + I +L  P+L   
Sbjct: 461 WVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPALSML 520

Query: 426 -KSVDLVIQELINTVKKCTKKLANFPRLCEET-ERIVANHIRERE 468
            K+++++ Q  IN  KK   +  N  +  + T E I   H  + E
Sbjct: 521 QKAMEIIQQAFINVAKKHFGEFFNLNQTVQSTIEDIKVKHTAKAE 565


>gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 135

 Score =  117 bits (293), Expect = 5e-26
 Identities = 67/119 (56%), Positives = 88/119 (73%), Gaps = 7/119 (5%)

Query: 631 DENGQAENF--SMDPQLERQVETIRNLVDSYMSIINKCIRDLI----PKTIMHLMINNVK 684
           +ENG +++F  SMDPQL  Q+ET ++LVDSY++I+NK + DL+    PKT MHLMINN+ 
Sbjct: 13  EENG-SDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMH 71

Query: 685 DFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTP 743
           +FI SELLA+LYS  D+N LME+S EQA+  +E L M+  L+EA  IIGDI T  VS P
Sbjct: 72  EFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMVSMP 130


>gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 135

 Score =  117 bits (293), Expect = 5e-26
 Identities = 67/119 (56%), Positives = 88/119 (73%), Gaps = 7/119 (5%)

Query: 631 DENGQAENF--SMDPQLERQVETIRNLVDSYMSIINKCIRDLI----PKTIMHLMINNVK 684
           +ENG +++F  SMDPQL  Q+ET ++LVDSY++I+NK + DL+    PKT MHLMINN+ 
Sbjct: 13  EENG-SDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMH 71

Query: 685 DFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTP 743
           +FI SELLA+LYS  D+N LME+S EQA+  +E L M+  L+EA  IIGDI T  VS P
Sbjct: 72  EFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMVSMP 130


>gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 155

 Score =  117 bits (293), Expect = 5e-26
 Identities = 67/119 (56%), Positives = 88/119 (73%), Gaps = 7/119 (5%)

Query: 631 DENGQAENF--SMDPQLERQVETIRNLVDSYMSIINKCIRDLI----PKTIMHLMINNVK 684
           +ENG +++F  SMDPQL  Q+ET ++LVDSY++I+NK + DL+    PKT MHLMINN+ 
Sbjct: 33  EENG-SDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMH 91

Query: 685 DFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTP 743
           +FI SELLA+LYS  D+N LME+S EQA+  +E L M+  L+EA  IIGDI T  VS P
Sbjct: 92  EFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMVSMP 150


>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
          Length = 1015

 Score =  103 bits (257), Expect = 7e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 317 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 376

Query: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 377 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 436

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 437 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 496

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 497 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 556

Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 557 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 613

Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
           ++    +  +    ++E E   +KN  P
Sbjct: 614 SVEQQADSFKATRFNLETE---WKNNYP 638


>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
          Length = 997

 Score =  103 bits (257), Expect = 7e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358

Query: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538

Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 539 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595

Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
           ++    +  +    ++E E   +KN  P
Sbjct: 596 SVEQQADSFKATRFNLETE---WKNNYP 620


>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
          Length = 979

 Score =  103 bits (257), Expect = 7e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340

Query: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520

Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 521 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577

Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
           ++    +  +    ++E E   +KN  P
Sbjct: 578 SVEQQADSFKATRFNLETE---WKNNYP 602


>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
          Length = 978

 Score =  103 bits (257), Expect = 7e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339

Query: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519

Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 520 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576

Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
           ++    +  +    ++E E   +KN  P
Sbjct: 577 SVEQQADSFKATRFNLETE---WKNNYP 601


>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
          Length = 961

 Score =  103 bits (257), Expect = 7e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322

Query: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502

Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 503 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559

Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
           ++    +  +    ++E E   +KN  P
Sbjct: 560 SVEQQADSFKATRFNLETE---WKNNYP 584


>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
          Length = 942

 Score =  103 bits (257), Expect = 7e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 244 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 303

Query: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 304 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 363

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 364 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 423

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 424 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 483

Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 484 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 540

Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
           ++    +  +    ++E E   +KN  P
Sbjct: 541 SVEQQADSFKATRFNLETE---WKNNYP 565


>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
          Length = 924

 Score =  103 bits (257), Expect = 7e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 226 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 285

Query: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 286 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 345

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 346 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 405

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 406 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 465

Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 466 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 522

Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
           ++    +  +    ++E E   +KN  P
Sbjct: 523 SVEQQADSFKATRFNLETE---WKNNYP 547


>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
          Length = 960

 Score =  103 bits (257), Expect = 7e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 262 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 321

Query: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 322 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 381

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 382 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 441

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 442 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 501

Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 502 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 558

Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
           ++    +  +    ++E E   +KN  P
Sbjct: 559 SVEQQADSFKATRFNLETE---WKNNYP 583


>gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens]
          Length = 105

 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 52/103 (50%), Positives = 65/103 (63%), Gaps = 3/103 (2%)

Query: 695 LYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ 754
           +YS  +QNTLMEE AEQAQ+ DEML M+ ALKEAL IIGDI+  TV+ P PPPVDD+W+Q
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWLQ 60

Query: 755 HSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSG 797
              +S P +   QR P  +AP +     +  A       PH G
Sbjct: 61  --VQSIPDAHRYQRLPP-TAPKSPTRDAQRSALGASGTPPHRG 100


>gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo
           sapiens]
          Length = 63

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 40/59 (67%), Positives = 48/59 (81%)

Query: 695 LYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWI 753
           +YS  +QNTLMEE AEQAQ+ DEML M+ ALKEAL IIGDI+  TV+ P PPPVDD+W+
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59


>gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo
           sapiens]
          Length = 63

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 40/59 (67%), Positives = 48/59 (81%)

Query: 695 LYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWI 753
           +YS  +QNTLMEE AEQAQ+ DEML M+ ALKEAL IIGDI+  TV+ P PPPVDD+W+
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59


>gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo
           sapiens]
          Length = 103

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 50/99 (50%), Positives = 62/99 (62%), Gaps = 12/99 (12%)

Query: 695 LYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ 754
           +YS  +QNTLMEE AEQAQ+ DEML M+ ALKEAL IIGDI+  TV+   PPPVDD+W+Q
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVT--MPPPVDDTWLQ 58

Query: 755 --------HSRRSPPPSPTTQRRPTLSAPLARPTSGRGP 785
                     +R PP +P +  R    + L   TSG  P
Sbjct: 59  VQSIPDAHRYQRLPPTAPKSPTRDAQRSALG--TSGTPP 95


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 34/98 (34%), Positives = 41/98 (41%), Gaps = 11/98 (11%)

Query: 743  PAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVP 802
            P PPP      Q     PPP P     P    PL  PT    P P +P P P       P
Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPALPSPP----PLVAPTPSSPPPPPLPPPPP-------P 1507

Query: 803  FRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVPSRRP 840
              P P PP P ++    APP+ P+ P+   P +P  RP
Sbjct: 1508 AMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 43/152 (28%), Positives = 62/152 (40%), Gaps = 9/152 (5%)

Query: 706  EESAEQAQRRDEMLRMYQALKEALGIIGDISTA---TVSTPAPPPVDDSWIQHSRRSPPP 762
            +E    A+ RD    + +++  A+  + D   A     STP  PP+  +         P 
Sbjct: 1383 DEEDSVAKNRD----LQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPG 1438

Query: 763  SPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPP 822
             P+     T   PL        P PA P+P P    PP P +P    P P  + +  +PP
Sbjct: 1439 LPSANSNGTPEPPLLEEKPPPTPPPA-PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP 1497

Query: 823  QVPSRPTRAPPSVPSRRPPPSPTRPTIIRPLE 854
              P  P   PP++PS  PPP P    +  P E
Sbjct: 1498 P-PPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 11/87 (12%)

Query: 768  RRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSR 827
            R+P    P+    SG+   P   S G  S  PP    P P P  P  + S   P Q P  
Sbjct: 1664 RKPWHRPPVPVRRSGQAKNPV--SAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPE- 1720

Query: 828  PTRAPPSVPSRRPPPSPTRPTIIRPLE 854
             T  P        PP+P +P+++RP+E
Sbjct: 1721 -TAMP-------EPPAPEKPSLLRPVE 1739



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 24/85 (28%), Positives = 28/85 (32%), Gaps = 4/85 (4%)

Query: 760 PPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFG 819
           PPP PT Q        L     G      +P P P      +   P P P    S+   G
Sbjct: 765 PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSP----SASKVG 820

Query: 820 APPQVPSRPTRAPPSVPSRRPPPSP 844
                P+    AP   P   PPP P
Sbjct: 821 VHLLEPATRDGAPQPPPPPPPPPPP 845



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 34/123 (27%), Positives = 46/123 (37%), Gaps = 14/123 (11%)

Query: 733  GDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTL----SAPLARPTSGRGPAPA 788
            GD        P PP  D        R+    P T   P L    + P   P++       
Sbjct: 972  GDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPET---PGLGLDPNKPPELPSTVNAEPLG 1028

Query: 789  IPSPGPHSGAPPVPFRPGPLPPFPSSSDSFG--APPQVPSRPTRAPPS----VPSRRPPP 842
            +   GPH  APP P  P P PP P+S    G  +P    ++P +   +    +  RR PP
Sbjct: 1029 LIQSGPHQAAPPPP-PPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPP 1087

Query: 843  SPT 845
              T
Sbjct: 1088 FQT 1090



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 15/89 (16%)

Query: 770  PTLSAPLARPTSGRGP-APAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRP 828
            P L+ P    T    P APA   PGP    PP+P  P        S++S G P   P   
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGP----PPLPGLP--------SANSNGTPE--PPLL 1453

Query: 829  TRAPPSVPSRRPPPSPTRPTIIRPLESSL 857
               PP  P   P P P  P    P + +L
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPAL 1482



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 31/112 (27%), Positives = 34/112 (30%), Gaps = 34/112 (30%)

Query: 743 PAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSP---------- 792
           P PPP            PPP P     P +   L       G  PA PSP          
Sbjct: 833 PQPPP------------PPPPPP----PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP 876

Query: 793 --------GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP 836
                   G     PP P   G  PP     D  GA      + T+AP  VP
Sbjct: 877 PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVP 928



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 5/63 (7%)

Query: 795 HSGAPPVPFRPGPLP---PFPSSS--DSFGAPPQVPSRPTRAPPSVPSRRPPPSPTRPTI 849
           H+  P   F  G LP    FPSSS   ++  P    SRP   P S+  + PP SP    +
Sbjct: 123 HTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGL 182

Query: 850 IRP 852
           + P
Sbjct: 183 LSP 185


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,537,827
Number of Sequences: 37866
Number of extensions: 1937032
Number of successful extensions: 28999
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 428
Number of HSP's successfully gapped in prelim test: 1504
Number of HSP's that attempted gapping in prelim test: 13645
Number of HSP's gapped (non-prelim): 9463
length of query: 859
length of database: 18,247,518
effective HSP length: 111
effective length of query: 748
effective length of database: 14,044,392
effective search space: 10505205216
effective search space used: 10505205216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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