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Search of human proteins with 209364623
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 891 0.0
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 877 0.0
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 664 0.0
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 426 e-119
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 139 7e-33
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 139 7e-33
gi|23510413 sorting nexin 26 [Homo sapiens] 136 3e-32
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 135 7e-32
gi|156119615 myosin IXA [Homo sapiens] 134 2e-31
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 134 2e-31
gi|188497642 ARHGAP15 [Homo sapiens] 132 6e-31
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 129 4e-30
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 129 4e-30
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 129 4e-30
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 128 9e-30
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 128 9e-30
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 127 3e-29
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 127 3e-29
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 127 3e-29
gi|229094128 active breakpoint cluster region-related protein i... 126 3e-29
gi|38679957 active breakpoint cluster region-related protein is... 126 3e-29
gi|38679954 active breakpoint cluster region-related protein is... 126 3e-29
gi|208022687 GTPase regulator associated with the focal adhesion... 126 3e-29
gi|7662208 GTPase regulator associated with the focal adhesion k... 126 3e-29
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 126 4e-29
gi|91208437 GEM interacting protein [Homo sapiens] 126 4e-29
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 125 7e-29
gi|186910302 Rac GTPase activating protein 1 [Homo sapiens] 122 8e-28
gi|186910300 Rac GTPase activating protein 1 [Homo sapiens] 122 8e-28
gi|21361397 Rac GTPase activating protein 1 [Homo sapiens] 122 8e-28
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 891 bits (2303), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD 60
MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD
Sbjct: 1 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD 60
Query: 61 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG 120
QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG
Sbjct: 61 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG 120
Query: 121 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS 180
LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS
Sbjct: 121 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS 180
Query: 181 EKRVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVY 240
EKRVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVY
Sbjct: 181 EKRVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVY 240
Query: 241 SCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKA 300
SCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKA
Sbjct: 241 SCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKA 300
Query: 301 DISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLL 360
DISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLL
Sbjct: 301 DISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLL 360
Query: 361 PPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRL 420
PPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRL
Sbjct: 361 PPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRL 420
Query: 421 VVELLIKNEDILF 433
VVELLIKNEDILF
Sbjct: 421 VVELLIKNEDILF 433
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 877 bits (2266), Expect = 0.0
Identities = 433/459 (94%), Positives = 433/459 (94%), Gaps = 26/459 (5%)
Query: 1 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD 60
MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD
Sbjct: 1 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD 60
Query: 61 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG 120
QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG
Sbjct: 61 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG 120
Query: 121 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS 180
LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS
Sbjct: 121 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS 180
Query: 181 EKR--------------------------VHTFRGPHWCEYCANFMWGLIAQGVKCADCG 214
EKR VHTFRGPHWCEYCANFMWGLIAQGVKCADCG
Sbjct: 181 EKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCG 240
Query: 215 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE 274
LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE
Sbjct: 241 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE 300
Query: 275 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY 334
GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY
Sbjct: 301 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY 360
Query: 335 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI 394
PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI
Sbjct: 361 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI 420
Query: 395 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
Sbjct: 421 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 664 bits (1713), Expect = 0.0
Identities = 321/452 (71%), Positives = 371/452 (82%), Gaps = 25/452 (5%)
Query: 7 DTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVA 66
D +EY+PP+WKSYLYQLQQEAP P+RI C EVENRPKYYGREFHG+ISRE AD+LL
Sbjct: 17 DAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGV 76
Query: 67 EGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYI 126
EG+Y++RESQRQPG YTLALRFG+QT N+RL++DGKHFVGEKRFESIHDLVTDGLITLYI
Sbjct: 77 EGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYI 136
Query: 127 ETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKE------THDERDSTGQDGVS 180
ETKAAEYI+KMT NPIYEH+GY TL RE ++ E TH+E + +
Sbjct: 137 ETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSL 196
Query: 181 EKR-------------------VHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQC 221
+R VHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLNVHKQC
Sbjct: 197 VRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQC 256
Query: 222 SKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSG 281
SK VPNDC+PDLK +KKVY CDLTTLVKAH T+RPMVVD+CIREIE+RGL SEGLYRVSG
Sbjct: 257 SKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSG 316
Query: 282 FSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESA 341
F++ IEDVKMAFDRDGEKADIS N+Y DINIITGALKLYFRDLPIP+ITYD Y KFI++A
Sbjct: 317 FTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAA 376
Query: 342 KIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLM 401
KI + DE+LE +HE L LLPPAH ETLRYLM HLK+VT++EK+N MNAENLGIVFGPTLM
Sbjct: 377 KISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLM 436
Query: 402 RSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
R PE + L+D+RYQ+L+V++LI+NED+LF
Sbjct: 437 RPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 426 bits (1096), Expect = e-119
Identities = 197/251 (78%), Positives = 227/251 (90%)
Query: 183 RVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSC 242
+VHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLNVHKQCSK VPNDC+PDLK +KKVY C
Sbjct: 82 KVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCC 141
Query: 243 DLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADI 302
DLTTLVKAH T+RPMVVD+CIREIE+RGL SEGLYRVSGF++ IEDVKMAFDRDGEKADI
Sbjct: 142 DLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADI 201
Query: 303 SVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPP 362
S N+Y DINIITGALKLYFRDLPIP+ITYD Y KFI++AKI + DE+LE +HE L LLPP
Sbjct: 202 SANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPP 261
Query: 363 AHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVV 422
AH ETLRYLM HLK+VT++EK+N MNAENLGIVFGPTLMR PE + L+D+RYQ+L+V
Sbjct: 262 AHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIV 321
Query: 423 ELLIKNEDILF 433
++LI+NED+LF
Sbjct: 322 QILIENEDVLF 332
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 139 bits (349), Expect = 7e-33
Identities = 71/190 (37%), Positives = 119/190 (62%), Gaps = 2/190 (1%)
Query: 238 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 297
+V+ C L L + ++ P V CIR +E+RGL+ +GLYR+SG I+ ++ D D
Sbjct: 325 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 383
Query: 298 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
E+ D+ +ED+++ITGALKL+FR+LP PL + + +FI + K+ D + + + +
Sbjct: 384 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 443
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 417
+ LP + +TLR L HL RV H ++N M+ +++ IVFGPTL+R PE++ + + +
Sbjct: 444 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLR-PEVEETSMPMTMVF 502
Query: 418 QRLVVELLIK 427
Q VVEL+++
Sbjct: 503 QNQVVELILQ 512
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 139 bits (349), Expect = 7e-33
Identities = 71/190 (37%), Positives = 119/190 (62%), Gaps = 2/190 (1%)
Query: 238 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 297
+V+ C L L + ++ P V CIR +E+RGL+ +GLYR+SG I+ ++ D D
Sbjct: 352 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 410
Query: 298 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
E+ D+ +ED+++ITGALKL+FR+LP PL + + +FI + K+ D + + + +
Sbjct: 411 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 470
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 417
+ LP + +TLR L HL RV H ++N M+ +++ IVFGPTL+R PE++ + + +
Sbjct: 471 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLR-PEVEETSMPMTMVF 529
Query: 418 QRLVVELLIK 427
Q VVEL+++
Sbjct: 530 QNQVVELILQ 539
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 136 bits (343), Expect = 3e-32
Identities = 74/202 (36%), Positives = 116/202 (57%), Gaps = 6/202 (2%)
Query: 237 KKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRD 296
++V+ CDL + P V+ C IE+ G+ +G+YR+SG S I+ ++ FD +
Sbjct: 310 QRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGV-VDGIYRLSGVSSNIQRLRHEFDSE 368
Query: 297 GEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEA 356
+DI+ ++ KLYFR+LP PL+TY Y KF E+ + +E+L +H+
Sbjct: 369 RIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDV 428
Query: 357 LKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAM-----AA 411
++ LPP H TL YL+ HL R+ H M+A NL IV+ P L+RS EL+++ AA
Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488
Query: 412 LNDIRYQRLVVELLIKNEDILF 433
++R Q +VVE L+ + D+LF
Sbjct: 489 FREVRVQSVVVEFLLTHVDVLF 510
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 135 bits (340), Expect = 7e-32
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 3/178 (1%)
Query: 258 VVDMCIREIESRGLNSEGLYRVSGFSDLIEDV-KMAFD-RDGEKADISVNMYEDINIITG 315
++ CI +E+RG+N +GLYRV G S ++ + M D + + D+ + ++ IT
Sbjct: 398 IIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITS 457
Query: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375
ALK Y R LP PL+TY+ + FI AK P+ ++ +H + LP + E L L+ HL
Sbjct: 458 ALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHL 517
Query: 376 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
V+ H K+NLM NLG+VFGPTLMR P+ + +AAL D+++Q +VVE+LI+N + +F
Sbjct: 518 TNVSNHSKQNLMTVANLGVVFGPTLMR-PQEETVAALMDLKFQNIVVEILIENHEKIF 574
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 134 bits (336), Expect = 2e-31
Identities = 85/273 (31%), Positives = 139/273 (50%), Gaps = 15/273 (5%)
Query: 163 VLKETHDERDSTGQDGVSEKRVHTFRG-----PHWCEYCANFMWGLIAQGVKCADCGLNV 217
V K +R D V E H F+ P +CEYC++ +W ++ + C C
Sbjct: 1978 VPKTERKKRRKKETDLVEEHNGHIFKATQYSIPTYCEYCSSLIW-IMDRASVCKLCKYAC 2036
Query: 218 HKQCSKMVPNDC--KPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEG 275
HK+C C K D + + + +L+ L T P+VV+ I IE GL +EG
Sbjct: 2037 HKKCCLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTV-PLVVEKLINYIEMHGLYTEG 2095
Query: 276 LYRVSGFSDLIEDVKMAFDRDGEKADISVNMYE-DINIITGALKLYFRDLPIPLITYDAY 334
+YR SG ++ I++++ D D E SVN+ + +I++I K + RDLP PL+T++ Y
Sbjct: 2096 IYRKSGSTNKIKELRQGLDTDAE----SVNLDDYNIHVIASVFKQWLRDLPNPLMTFELY 2151
Query: 335 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI 394
+F+ + + + E + ++ + L H TL L+ HL R+ L E N M+A L I
Sbjct: 2152 EEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAI 2211
Query: 395 VFGPTLMRSPE-LDAMAALNDIRYQRLVVELLI 426
VF P ++R P+ D + ++ DI VEL++
Sbjct: 2212 VFAPCILRCPDTTDPLQSVQDISKTTTCVELIV 2244
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 134 bits (336), Expect = 2e-31
Identities = 73/185 (39%), Positives = 110/185 (59%), Gaps = 1/185 (0%)
Query: 250 AHTTKR-PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYE 308
AHT + P++VD+C + +E RGL G+YRV G + I ++ ++ DI + +
Sbjct: 1155 AHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWR 1214
Query: 309 DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETL 368
D+N+I+ LK +FR LP PL T D Y FIE+ + DP ++L+TL + LP H ETL
Sbjct: 1215 DLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETL 1274
Query: 369 RYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKN 428
++L AHLK V + ++N M NL IVFGPTL+R+ E + + + Q +VE LI++
Sbjct: 1275 KFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQH 1334
Query: 429 EDILF 433
D F
Sbjct: 1335 HDWFF 1339
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 132 bits (332), Expect = 6e-31
Identities = 64/196 (32%), Positives = 119/196 (60%), Gaps = 2/196 (1%)
Query: 238 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 297
+++ L + + + P V CI +E RGL+ +G+YRVSG I+ ++ +++
Sbjct: 277 QIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQE- 335
Query: 298 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
EK ++ + +EDI+++TGALK++FR+LP PL Y + +F+E+ K D + ++E + +
Sbjct: 336 EKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLV 395
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 417
+ LPP + +T++ L HL ++ +NLM+ ++LGIVFGPTL+R+ A++ + Y
Sbjct: 396 QKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMV-Y 454
Query: 418 QRLVVELLIKNEDILF 433
Q + EL++ +F
Sbjct: 455 QNQIAELMLSEYSKIF 470
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 129 bits (325), Expect = 4e-30
Identities = 71/208 (34%), Positives = 118/208 (56%), Gaps = 1/208 (0%)
Query: 227 NDCKPDLKHVKKVYSCDLTTLVKAHTTKR-PMVVDMCIREIESRGLNSEGLYRVSGFSDL 285
N K + K + + L A +R P++V C R +E+RGL S G+YRV G + +
Sbjct: 796 NIIKKNKKAAPRAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAV 855
Query: 286 IEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMD 345
+ ++ +R ++ ++D+N+I+ LK +FR LP PL T D Y FIE+ +I D
Sbjct: 856 VSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIED 915
Query: 346 PDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPE 405
E++ TL + ++ LP + ETL++L+ HLK + H ++N M NL +VFGPTL+R+ E
Sbjct: 916 ARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSE 975
Query: 406 LDAMAALNDIRYQRLVVELLIKNEDILF 433
+ + + + +VE LI++ D F
Sbjct: 976 DNMTDMVTHMPDRYKIVETLIQHSDWFF 1003
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 129 bits (325), Expect = 4e-30
Identities = 73/176 (41%), Positives = 100/176 (56%), Gaps = 3/176 (1%)
Query: 239 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 298
V+ + + K +K P +V C+ EIE RG+ G+YRVSG + I+ +K AFD + +
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1066
Query: 299 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
D+SV M E D+N I G LKLYFR+LP PL T + YP F E + DP + + L
Sbjct: 1067 --DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLL 1124
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALN 413
LP A+ T +L+ HLKRV E N M+ NL VFGPTL+R E ++ N
Sbjct: 1125 LSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPAN 1180
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 129 bits (325), Expect = 4e-30
Identities = 73/176 (41%), Positives = 100/176 (56%), Gaps = 3/176 (1%)
Query: 239 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 298
V+ + + K +K P +V C+ EIE RG+ G+YRVSG + I+ +K AFD + +
Sbjct: 1051 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1110
Query: 299 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
D+SV M E D+N I G LKLYFR+LP PL T + YP F E + DP + + L
Sbjct: 1111 --DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLL 1168
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALN 413
LP A+ T +L+ HLKRV E N M+ NL VFGPTL+R E ++ N
Sbjct: 1169 LSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPAN 1224
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 128 bits (322), Expect = 9e-30
Identities = 71/178 (39%), Positives = 104/178 (58%), Gaps = 3/178 (1%)
Query: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S+ + +N + G
Sbjct: 1275 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1332
Query: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375
ALK +F DLP PLI Y +P+ +E+AKI D E+L L E +K P + + RY++ HL
Sbjct: 1333 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1392
Query: 376 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
RV+ K NLM A+NL I F PTLMR P+ + L+ + + VVE I+ F
Sbjct: 1393 NRVSQQHKINLMTADNLSICFWPTLMR-PDFENREFLSTTKIHQSVVETFIQQCQFFF 1449
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 128 bits (322), Expect = 9e-30
Identities = 71/178 (39%), Positives = 104/178 (58%), Gaps = 3/178 (1%)
Query: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S+ + +N + G
Sbjct: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331
Query: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375
ALK +F DLP PLI Y +P+ +E+AKI D E+L L E +K P + + RY++ HL
Sbjct: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
Query: 376 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
RV+ K NLM A+NL I F PTLMR P+ + L+ + + VVE I+ F
Sbjct: 1392 NRVSQQHKINLMTADNLSICFWPTLMR-PDFENREFLSTTKIHQSVVETFIQQCQFFF 1448
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 127 bits (318), Expect = 3e-29
Identities = 101/358 (28%), Positives = 169/358 (47%), Gaps = 30/358 (8%)
Query: 87 RFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHV 146
+F S + +GK VG K + +V L T + K + + + + E
Sbjct: 1542 KFRSNIKTMYSVPNGKIHVGYKDLMENYQIVVSNLATERGQ-KDTNLVLNLFQSLLDEFT 1600
Query: 147 -GYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRVHTFRG-----PHWCEYCANFM 200
GYT + EP K+ K+ ER V E H F P CE C +++
Sbjct: 1601 RGYTKNDFEPV-KQSKAQKKKRKQER------AVQEHNGHVFASYQVSIPQSCEQCLSYI 1653
Query: 201 WGLIAQGVKCADCGLNVHKQCSKMVPNDC--------KPDLKHVKKVYSCDLTTLVKAHT 252
W L+ + + C+ C + HK+C + + C +P ++ D T KA
Sbjct: 1654 W-LMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCVDSLTSDKASV 1712
Query: 253 TKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINI 312
P+V++ + +E GL +EGLYR SG ++ +++ A D A + + + I+
Sbjct: 1713 ---PIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFP-IHA 1766
Query: 313 ITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLM 372
ITG LK + R+LP PL+T+ Y F+ + ++ + EQL ++ L+ LP A+ +L L+
Sbjct: 1767 ITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLI 1826
Query: 373 AHLKRVTLHEKENLMNAENLGIVFGPTLMRSPE-LDAMAALNDIRYQRLVVELLIKNE 429
HL +V L E N M+ L I+F P L+R P+ D + ++ D+ VE+LIK +
Sbjct: 1827 FHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQ 1884
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 127 bits (318), Expect = 3e-29
Identities = 101/358 (28%), Positives = 169/358 (47%), Gaps = 30/358 (8%)
Query: 87 RFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHV 146
+F S + +GK VG K + +V L T + K + + + + E
Sbjct: 1542 KFRSNIKTMYSVPNGKIHVGYKDLMENYQIVVSNLATERGQ-KDTNLVLNLFQSLLDEFT 1600
Query: 147 -GYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRVHTFRG-----PHWCEYCANFM 200
GYT + EP K+ K+ ER V E H F P CE C +++
Sbjct: 1601 RGYTKNDFEPV-KQSKAQKKKRKQER------AVQEHNGHVFASYQVSIPQSCEQCLSYI 1653
Query: 201 WGLIAQGVKCADCGLNVHKQCSKMVPNDC--------KPDLKHVKKVYSCDLTTLVKAHT 252
W L+ + + C+ C + HK+C + + C +P ++ D T KA
Sbjct: 1654 W-LMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCVDSLTSDKASV 1712
Query: 253 TKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINI 312
P+V++ + +E GL +EGLYR SG ++ +++ A D A + + + I+
Sbjct: 1713 ---PIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFP-IHA 1766
Query: 313 ITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLM 372
ITG LK + R+LP PL+T+ Y F+ + ++ + EQL ++ L+ LP A+ +L L+
Sbjct: 1767 ITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLI 1826
Query: 373 AHLKRVTLHEKENLMNAENLGIVFGPTLMRSPE-LDAMAALNDIRYQRLVVELLIKNE 429
HL +V L E N M+ L I+F P L+R P+ D + ++ D+ VE+LIK +
Sbjct: 1827 FHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQ 1884
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 127 bits (318), Expect = 3e-29
Identities = 65/196 (33%), Positives = 122/196 (62%), Gaps = 3/196 (1%)
Query: 238 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 297
+V+ +L L + P V +CI +E GL+ +G+YRVSG +I+ ++ A + D
Sbjct: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710
Query: 298 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
EK D++ + +EDI++ITGALK++FR+LP PL T++ + F+ + K +P +++ + + +
Sbjct: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 417
+ LP + +T++ L HL+RV + ++N M +++ IVFGPTL++ + A++ + Y
Sbjct: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828
Query: 418 QRLVVELLIKNEDILF 433
Q +VEL++ +F
Sbjct: 829 QNQIVELILLELSSIF 844
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 126 bits (317), Expect = 3e-29
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)
Query: 239 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 298
V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + +
Sbjct: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
Query: 299 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L
Sbjct: 658 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 715
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 412
+ LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L
Sbjct: 716 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 770
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 126 bits (317), Expect = 3e-29
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)
Query: 239 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 298
V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + +
Sbjct: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
Query: 299 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L
Sbjct: 704 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 761
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 412
+ LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L
Sbjct: 762 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 816
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 126 bits (317), Expect = 3e-29
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)
Query: 239 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 298
V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + +
Sbjct: 607 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 666
Query: 299 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L
Sbjct: 667 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 724
Query: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 412
+ LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L
Sbjct: 725 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 779
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 126 bits (317), Expect = 3e-29
Identities = 63/178 (35%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
Query: 258 VVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAF--DRDGEKADISVNMYEDINIITG 315
++ CI +E+RG+N +GLYR+ G + ++ + + + + + +I IT
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
Query: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375
ALK Y R LP PL+ Y FI++AK+ + + ++ +H + LP + + L+ LM HL
Sbjct: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
Query: 376 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
V + K+NLM NLG+VFGPTL+R P+ + +AA+ DI++Q +V+E+LI+N + +F
Sbjct: 512 ANVANNHKQNLMTVANLGVVFGPTLLR-PQEETVAAIMDIKFQNIVIEILIENHEKIF 568
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 126 bits (317), Expect = 3e-29
Identities = 63/178 (35%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
Query: 258 VVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAF--DRDGEKADISVNMYEDINIITG 315
++ CI +E+RG+N +GLYR+ G + ++ + + + + + +I IT
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
Query: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375
ALK Y R LP PL+ Y FI++AK+ + + ++ +H + LP + + L+ LM HL
Sbjct: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
Query: 376 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
V + K+NLM NLG+VFGPTL+R P+ + +AA+ DI++Q +V+E+LI+N + +F
Sbjct: 512 ANVANNHKQNLMTVANLGVVFGPTLLR-PQEETVAAIMDIKFQNIVIEILIENHEKIF 568
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 126 bits (316), Expect = 4e-29
Identities = 71/194 (36%), Positives = 113/194 (58%), Gaps = 4/194 (2%)
Query: 240 YSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEK 299
+ LTT+V P+ ++ CI IE+ GL++EG+YRVSG +E ++ FD+D
Sbjct: 1247 FGVPLTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HN 1304
Query: 300 ADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKL 359
D++ + +N + GA+K +F +LP PL+ Y+ +E+ KI D +++L L E LK
Sbjct: 1305 LDLAEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKK 1363
Query: 360 LPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQR 419
P + E +Y+++HL +V+ + K NLM +ENL I F PTLMR P+ M AL R +
Sbjct: 1364 FPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQ 1422
Query: 420 LVVELLIKNEDILF 433
++EL I+ F
Sbjct: 1423 TIIELFIQQCPFFF 1436
>gi|91208437 GEM interacting protein [Homo sapiens]
Length = 970
Score = 126 bits (316), Expect = 4e-29
Identities = 89/270 (32%), Positives = 132/270 (48%), Gaps = 26/270 (9%)
Query: 183 RVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDC-KPDLKHVKKVYS 241
++ RGP C C FM G +C +C L HK+C + + C L ++
Sbjct: 495 QLRRLRGPAKCRECEAFM----VSGTECEECFLTCHKRCLETLLILCGHRRLPARTPLFG 550
Query: 242 CDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKAD 301
D L + + P VV C EIE R L+ +G+YRVSG +E + AF+ +
Sbjct: 551 VDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVE 610
Query: 302 ISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPD------------EQ 349
+S N D++ + LK + ++L P+I + Y FI AK + D E
Sbjct: 611 LSGNSPHDVSSV---LKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEV 667
Query: 350 LETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAM 409
+ +L L LP ++ TLR+L+AHL RV EN M+A NLGIVFGPTL+R P+
Sbjct: 668 IRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRA 727
Query: 410 AA------LNDIRYQRLVVELLIKNEDILF 433
A+ L D +Q +VE LI + + +F
Sbjct: 728 ASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 125 bits (314), Expect = 7e-29
Identities = 69/206 (33%), Positives = 116/206 (56%), Gaps = 8/206 (3%)
Query: 234 KHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAF 293
K + CDLT +++ P V+ C IE+ G+ +G+YR+SG + I+ ++ F
Sbjct: 13 KGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGI-VDGIYRLSGVTSNIQRLRQEF 71
Query: 294 DRDGEKADISVNMY-EDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLET 352
D + D++ +Y +DI+ + KLYFR+LP PL+TY+ Y KF E+ + QL
Sbjct: 72 GSD-QCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLAR 130
Query: 353 LHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAM--- 409
+ ++ LPP+H TL YL+ HL + + M+A NL +V+ P L+RS E++A
Sbjct: 131 IQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCN 190
Query: 410 --AALNDIRYQRLVVELLIKNEDILF 433
AA +R Q++V+E ++ + D +F
Sbjct: 191 GDAAFLAVRVQQVVIEFILNHVDQIF 216
>gi|186910302 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 122 bits (305), Expect = 8e-28
Identities = 90/271 (33%), Positives = 132/271 (48%), Gaps = 15/271 (5%)
Query: 166 ETHDERDSTGQ-DGVSEKRVHTFRG-----PHWCEYCAN-FMWGLIAQGVKCADCGLNVH 218
E E DS G R+H F P C C +G ++ +KC DC + H
Sbjct: 267 EPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSH 324
Query: 219 KQCSKMVPNDCKPDLKHVK-KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLY 277
+C P C P L K+ L V + P +V C+ EIE RGL GLY
Sbjct: 325 PECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLY 384
Query: 278 RVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKF 337
R+SG ++++K F R K ++ +DI+ I LK + R+L PL+T+ F
Sbjct: 385 RISGCDRTVKELKEKFLR--VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAF 442
Query: 338 IESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFG 397
+E+A+I D D + +++A+ LP A+ +TL +LM HL+RV M+ NL VFG
Sbjct: 443 MEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFG 501
Query: 398 PTLMRS--PELDAMAALNDIRYQRLVVELLI 426
PT++ P D + L DI+ Q VVE L+
Sbjct: 502 PTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
>gi|186910300 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 122 bits (305), Expect = 8e-28
Identities = 90/271 (33%), Positives = 132/271 (48%), Gaps = 15/271 (5%)
Query: 166 ETHDERDSTGQ-DGVSEKRVHTFRG-----PHWCEYCAN-FMWGLIAQGVKCADCGLNVH 218
E E DS G R+H F P C C +G ++ +KC DC + H
Sbjct: 267 EPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSH 324
Query: 219 KQCSKMVPNDCKPDLKHVK-KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLY 277
+C P C P L K+ L V + P +V C+ EIE RGL GLY
Sbjct: 325 PECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLY 384
Query: 278 RVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKF 337
R+SG ++++K F R K ++ +DI+ I LK + R+L PL+T+ F
Sbjct: 385 RISGCDRTVKELKEKFLR--VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAF 442
Query: 338 IESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFG 397
+E+A+I D D + +++A+ LP A+ +TL +LM HL+RV M+ NL VFG
Sbjct: 443 MEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFG 501
Query: 398 PTLMRS--PELDAMAALNDIRYQRLVVELLI 426
PT++ P D + L DI+ Q VVE L+
Sbjct: 502 PTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
>gi|21361397 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 122 bits (305), Expect = 8e-28
Identities = 90/271 (33%), Positives = 132/271 (48%), Gaps = 15/271 (5%)
Query: 166 ETHDERDSTGQ-DGVSEKRVHTFRG-----PHWCEYCAN-FMWGLIAQGVKCADCGLNVH 218
E E DS G R+H F P C C +G ++ +KC DC + H
Sbjct: 267 EPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSH 324
Query: 219 KQCSKMVPNDCKPDLKHVK-KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLY 277
+C P C P L K+ L V + P +V C+ EIE RGL GLY
Sbjct: 325 PECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLY 384
Query: 278 RVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKF 337
R+SG ++++K F R K ++ +DI+ I LK + R+L PL+T+ F
Sbjct: 385 RISGCDRTVKELKEKFLR--VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAF 442
Query: 338 IESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFG 397
+E+A+I D D + +++A+ LP A+ +TL +LM HL+RV M+ NL VFG
Sbjct: 443 MEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFG 501
Query: 398 PTLMRS--PELDAMAALNDIRYQRLVVELLI 426
PT++ P D + L DI+ Q VVE L+
Sbjct: 502 PTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,568,246
Number of Sequences: 37866
Number of extensions: 736494
Number of successful extensions: 3475
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 163
Number of HSP's that attempted gapping in prelim test: 2748
Number of HSP's gapped (non-prelim): 704
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.