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Search of human proteins with 207113164
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform
f [Homo sapiens]
(1412 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 2705 0.0
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 2699 0.0
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 2535 0.0
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 2452 0.0
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 2446 0.0
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 1510 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 149 1e-35
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 141 5e-33
gi|150170670 piccolo isoform 2 [Homo sapiens] 125 2e-28
gi|150378539 piccolo isoform 1 [Homo sapiens] 125 2e-28
gi|91982772 mucin 17 [Homo sapiens] 118 4e-26
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 115 4e-25
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 115 4e-25
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 113 1e-24
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 110 7e-24
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 110 7e-24
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 105 2e-22
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 105 2e-22
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 101 6e-21
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 101 6e-21
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 100 8e-21
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ... 100 8e-21
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 100 1e-20
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 100 1e-20
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 100 1e-20
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 99 4e-20
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 97 1e-19
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 97 1e-19
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 97 1e-19
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 97 1e-19
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 2705 bits (7012), Expect = 0.0
Identities = 1412/1412 (100%), Positives = 1412/1412 (100%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATP 240
Query: 241 APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 300
APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP
Sbjct: 241 APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 300
Query: 301 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR
Sbjct: 301 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
Query: 361 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420
AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV
Sbjct: 361 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420
Query: 421 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 480
KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD
Sbjct: 421 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 480
Query: 481 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS 540
GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS
Sbjct: 481 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS 540
Query: 541 ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 600
ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG
Sbjct: 541 ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 600
Query: 601 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 660
SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ
Sbjct: 601 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 660
Query: 661 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 720
GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA
Sbjct: 661 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 720
Query: 721 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780
RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA
Sbjct: 721 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780
Query: 781 AQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 840
AQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG
Sbjct: 781 AQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 840
Query: 841 KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900
KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ
Sbjct: 841 KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900
Query: 901 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM 960
AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM
Sbjct: 901 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM 960
Query: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1020
AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS
Sbjct: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1020
Query: 1021 SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE 1080
SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE
Sbjct: 1021 SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE 1080
Query: 1081 EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1140
EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS
Sbjct: 1081 EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1140
Query: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1200
QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK
Sbjct: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1200
Query: 1201 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1260
PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE
Sbjct: 1201 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1260
Query: 1261 SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKAS 1320
SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKAS
Sbjct: 1261 SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKAS 1320
Query: 1321 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1380
GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE
Sbjct: 1321 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1380
Query: 1381 KKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
KKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1381 KKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 2699 bits (6996), Expect = 0.0
Identities = 1411/1412 (99%), Positives = 1411/1412 (99%), Gaps = 1/1412 (0%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATP 240
Query: 241 APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 300
APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP
Sbjct: 241 APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 300
Query: 301 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR
Sbjct: 301 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
Query: 361 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420
AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV
Sbjct: 361 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420
Query: 421 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 480
KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD
Sbjct: 421 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 480
Query: 481 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS 540
GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS
Sbjct: 481 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS 540
Query: 541 ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 600
ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG
Sbjct: 541 ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 600
Query: 601 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 660
SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ
Sbjct: 601 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 660
Query: 661 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 720
GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA
Sbjct: 661 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 720
Query: 721 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780
RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA
Sbjct: 721 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780
Query: 781 AQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 840
AQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG
Sbjct: 781 AQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 840
Query: 841 KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900
KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ
Sbjct: 841 KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900
Query: 901 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM 960
AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM
Sbjct: 901 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM 960
Query: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1020
AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS
Sbjct: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1020
Query: 1021 SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE 1080
SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE
Sbjct: 1021 SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE 1080
Query: 1081 EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1140
EDGEGPQGAKSAHTL GPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS
Sbjct: 1081 EDGEGPQGAKSAHTL-GPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1139
Query: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1200
QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK
Sbjct: 1140 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1199
Query: 1201 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1260
PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE
Sbjct: 1200 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1259
Query: 1261 SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKAS 1320
SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKAS
Sbjct: 1260 SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKAS 1319
Query: 1321 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1380
GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE
Sbjct: 1320 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1379
Query: 1381 KKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
KKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1380 KKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1411
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 2535 bits (6571), Expect = 0.0
Identities = 1356/1489 (91%), Positives = 1376/1489 (92%), Gaps = 78/1489 (5%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGK---------TGNSMPHPATGKTVAN--------------------- 150
MKEKAKAETEKAGK TG ++ + +GK+
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 151 ---------LLSGKSPRKSAEPSANTTLVSETEEEGSV---------------PAFGAAA 186
++S S+E +++++ ++ E + SV PA AA
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 187 KPGMVS-------------------AGQADSSSEDTSSSSDE----TDVEVKASEKILQV 223
PG V + SSE+ S S +E T +VKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 224 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 343
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 344 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 404 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 463
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 464 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
Query: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1140
Query: 1064 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1123
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL GPTPSRTETLVEETAAESSEDDVVAPS
Sbjct: 1141 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL-GPTPSRTETLVEETAAESSEDDVVAPS 1199
Query: 1124 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1183
QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK
Sbjct: 1200 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1259
Query: 1184 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1243
TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL
Sbjct: 1260 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1319
Query: 1244 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1303
TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP
Sbjct: 1320 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1379
Query: 1304 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1363
EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK
Sbjct: 1380 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1439
Query: 1364 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1440 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 2452 bits (6355), Expect = 0.0
Identities = 1319/1489 (88%), Positives = 1339/1489 (89%), Gaps = 115/1489 (7%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGK---------TGNSMPHPATGKTVAN--------------------- 150
MKEKAKAETEKAGK TG ++ + +GK+
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 151 ---------LLSGKSPRKSAEPSANTTLVSETEEEGSV---------------PAFGAAA 186
++S S+E +++++ ++ E + SV PA AA
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 187 KPGMVS-------------------AGQADSSSEDTSSSSDE----TDVEVKASEKILQV 223
PG V + SSE+ S S +E T +VKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 224 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 343
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 344 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 404 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 463
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 464 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ------------------- 1061
Query: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1062 -------------------VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
Query: 1064 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1123
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS
Sbjct: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1162
Query: 1124 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1183
QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK
Sbjct: 1163 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1222
Query: 1184 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1243
TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL
Sbjct: 1223 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1282
Query: 1244 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1303
TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP
Sbjct: 1283 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1342
Query: 1304 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1363
EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK
Sbjct: 1343 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1402
Query: 1364 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1403 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1451
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 2446 bits (6339), Expect = 0.0
Identities = 1318/1489 (88%), Positives = 1338/1489 (89%), Gaps = 116/1489 (7%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGK---------TGNSMPHPATGKTVAN--------------------- 150
MKEKAKAETEKAGK TG ++ + +GK+
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 151 ---------LLSGKSPRKSAEPSANTTLVSETEEEGSV---------------PAFGAAA 186
++S S+E +++++ ++ E + SV PA AA
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 187 KPGMVS-------------------AGQADSSSEDTSSSSDE----TDVEVKASEKILQV 223
PG V + SSE+ S S +E T +VKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 224 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 343
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 344 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 404 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 463
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 464 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ------------------- 1061
Query: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1062 -------------------VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
Query: 1064 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1123
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL GPTPSRTETLVEETAAESSEDDVVAPS
Sbjct: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL-GPTPSRTETLVEETAAESSEDDVVAPS 1161
Query: 1124 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1183
QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK
Sbjct: 1162 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1221
Query: 1184 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1243
TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL
Sbjct: 1222 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1281
Query: 1244 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1303
TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP
Sbjct: 1282 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1341
Query: 1304 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1363
EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK
Sbjct: 1342 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1401
Query: 1364 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1402 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1450
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 1510 bits (3910), Expect = 0.0
Identities = 821/953 (86%), Positives = 841/953 (88%), Gaps = 77/953 (8%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGK---------TGNSMPHPATGKTVAN--------------------- 150
MKEKAKAETEKAGK TG ++ + +GK+
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 151 ---------LLSGKSPRKSAEPSANTTLVSETEEEGSV---------------PAFGAAA 186
++S S+E +++++ ++ E + SV PA AA
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 187 KPGMVS-------------------AGQADSSSEDTSSSSDE----TDVEVKASEKILQV 223
PG V + SSE+ S S +E T +VKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 224 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 343
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 344 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 404 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 463
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 464 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 876
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Score = 254 bits (648), Expect = 5e-67
Identities = 282/927 (30%), Positives = 367/927 (39%), Gaps = 179/927 (19%)
Query: 380 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 439
RK AA + D S+SE S+ + EA A A + + V A
Sbjct: 63 RKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMK 122
Query: 440 LGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNIL 499
A GK G + P GK + S + T V+ +E+
Sbjct: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG----- 177
Query: 500 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 559
S PA G K G V A + +SE + SSD D E KP++
Sbjct: 178 -----SVPAFGAAAKPG----MVSAGQADSSSEDTSSSSDETDVE----------GKPSV 218
Query: 560 KIPQTKACPKKTNTTASAKVAPV--RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 617
K Q KA T + + K AP +VG P+ G A PA + ++P E+S
Sbjct: 219 KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA-------KKPEEESE 271
Query: 618 SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 677
SSEE SE E+ A T Q K+ K LQV+AAS P KG+ G+G P PGK G +Q
Sbjct: 272 SSEEG-SESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 330
Query: 678 KAEK-QEDSESSEEES-DSEE---AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 732
KA K +EDSESS EES DSEE AA + Q K S K +Q A A A+ KG AP
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 733 GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP-EEDS 791
P K P V A+AQ G EEDS
Sbjct: 391 --------------PGKTGPAV--------------------------AKAQAGKREEDS 410
Query: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA-- 849
SS EESDSEEEA AQ KPSGK Q+RAA APAKESPRKGAAP PP KTGP+AAQ
Sbjct: 411 QSSSEESDSEEEAP--AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 468
Query: 850 GKQD-DSGSSSEESDSDGEAPAAVTSAQV--------IKPPLIF-VDPNRSPAGPAATPA 899
GKQ+ DS SSSEESDSD EA AA+ +AQV +KP + P AGP P
Sbjct: 469 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP-PG 527
Query: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP--- 956
+ A+ + E + SSS ES D + P ++ + A P +P
Sbjct: 528 KVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG 587
Query: 957 --------------KASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKV 1002
+ M + SS+ESS +D ++ T K +P T+A K
Sbjct: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
Query: 1003 LAQKASEAQPPV-----------ARTQPSSGVDSAVGTLPATSPQSTSV----------- 1040
AS PV T P+ + G + S+S
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707
Query: 1041 ------QAKGTNKLRKPKLPEV-----------------------QQATKAPESSDDSED 1071
QAK K + K V Q + E S+ SE+
Sbjct: 708 LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEE 767
Query: 1072 SSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS-QSLLSGY 1130
SDS + + K P +R + +A A + Q S
Sbjct: 768 ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 827
Query: 1131 MTPGLTPANSQASKATPKLDSSPSVSSTLAA---------KDDPDGKQEAKPQQAAGMLS 1181
P P NS P S PSV +A +D ++E+ ++ A L+
Sbjct: 828 KPPVRNPQNSTVLARGPA--SVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLA 885
Query: 1182 P-KTGGK--EAASGTTPQKSRKPKKGA 1205
K GK + + P K P+KGA
Sbjct: 886 QVKPSGKTHQIRAALAPAK-ESPRKGA 911
Score = 197 bits (501), Expect = 6e-50
Identities = 174/457 (38%), Positives = 222/457 (48%), Gaps = 88/457 (19%)
Query: 80 DPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSM 139
D S+SE S + + E TA A P + ++L A SS AK +KAG
Sbjct: 544 DSESSSEESSDSSDGEVPTAVA-PAQEKSLGNILQAKPTSS---PAKGPPQKAGP----- 594
Query: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
VA + + P ++E S ++ +++EE P ++A QA +
Sbjct: 595 --------VAVQVKAEKPMDNSESSEESSDSADSEEA-----------PAAMTAAQAKPA 635
Query: 200 SEDTSSSSDETDVEVKASEKILQVRAAS-APAKGTPGKGATPAPPGKAGAVASQTKAGKP 258
+ + + AS K+ VR + AP K G +P G + AVA T+ +P
Sbjct: 636 LKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA----GTATSPAGSSPAVAGGTQ--RP 689
Query: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318
EDS SSSEES EE+T A + QAK+ GK QV AAS P K S +G AP PGKTG
Sbjct: 690 AEDS-SSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTG 748
Query: 319 PAVAKAQAGKREEDSQSSSEESDSEEEA--PAQAKPSGKAPQVRAASAPAKESPRKGAAP 376
P V + +A K +EDS+SS EESDSEE A PAQ K S K Q +A A A+ KG
Sbjct: 749 PTVTQVKAEK-QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTIS 807
Query: 377 AP--------------PRKT---------------GPA-----------AAQVQVGKQEE 396
AP P K GPA AAQ Q G EE
Sbjct: 808 APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP-EE 866
Query: 397 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 456
DS SS EESDS+ EA AQVKP GK+ Q++ A KGA P PPGK GP+
Sbjct: 867 DSGSSEEESDSEEEA---ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPS- 922
Query: 457 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK 493
+AQ GK ++DS SSSEES SDGE P AV AQ++
Sbjct: 923 -AAQAGK-QDDSGSSSEES--DSDGEAPAAVTSAQDQ 955
Score = 94.4 bits (233), Expect = 7e-19
Identities = 80/215 (37%), Positives = 109/215 (50%), Gaps = 30/215 (13%)
Query: 86 ESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATG 145
+S EEE+++E A A+P A +SV + KA +A ++ P
Sbjct: 761 DSESSEEESDSEEAAASP--AQVKTSV------KKTQAKANPAAARAPSAKGTISAPGKV 812
Query: 146 KTVANLLSGKSPRKSAEP---SANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
T A +SP K P N+T+++ SVP+ G A + +A QA + E+
Sbjct: 813 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGP--ASVPSVGKA----VATAAQAQTGPEE 866
Query: 203 TSSSSDE---------TDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 253
S SS+E T +VK S K Q+RAA APAK +P KGA P PPGK G A+Q
Sbjct: 867 DSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ- 925
Query: 254 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKAS 288
AGK ++DS SSSEES DS+ E PAA Q + S
Sbjct: 926 -AGK-QDDSGSSSEES-DSDGEAPAAVTSAQDQES 957
Score = 68.2 bits (165), Expect = 5e-11
Identities = 153/750 (20%), Positives = 257/750 (34%), Gaps = 175/750 (23%)
Query: 673 TVTQVKAEKQEDSESSEEESDSEEAA--ASPAQVKTSVKKTQAKANPAAARAPSAKGTIS 730
T+ + Q+ SE + E+AA A +V + +++ A A +AK T
Sbjct: 45 TLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKAT-- 102
Query: 731 APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEED 790
P NS+VL A +PS ++ A+A+T
Sbjct: 103 ----------------------PRLASTNSSVLG---ADLPS---SMKEKAKAETEKAGK 134
Query: 791 SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 850
+G+S + + L K K+ + A E+ +G+ P P AG
Sbjct: 135 TGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG 194
Query: 851 KQD----DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAST 906
+ D D+ SSS+E+D +G+ P+ PAQ +A+S
Sbjct: 195 QADSSSEDTSSSSDETDVEGK--------------------------PSVKPAQVKASSV 228
Query: 907 PRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSS 966
K ES AR ++ PA PG + VT + P
Sbjct: 229 STK----ESPARKAA---------PA-----PG-KVGDVTPQVKGGALPPAKRAKKPEEE 269
Query: 967 KESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSA 1026
ESS ++E PA S+ +A+ K+L +A+ A P+ G
Sbjct: 270 SESSEEGSESEEEAPAGTRSQ--------VKASEKILQVRAASA--------PAKGTPG- 312
Query: 1027 VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP 1086
KG K V TKA + +DSE SS+ SS SEE+
Sbjct: 313 ----------------KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE---- 352
Query: 1087 QGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA-NSQASKA 1145
TP+ L + + ++S+ V + + G PA + A
Sbjct: 353 ------------TPAAKALLQAKASGKTSQ---VGAASAPAKESPRKGAAPAPPGKTGPA 397
Query: 1146 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGA 1205
K + + ++ ++ D ++EA Q +P+ A + +P+K P
Sbjct: 398 VAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP---- 453
Query: 1206 GNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKG 1265
P A Q V K ++E + +S R+
Sbjct: 454 -------------------APPRKTGPAAAQVQVGK------QEEDSRSSSEESDSDREA 488
Query: 1266 WESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEAS--VSPEKT--STTSKGKAKRDKASG 1321
+ + +P ++P+ K +G G G+ + V P K +T S K ++ S
Sbjct: 489 LAA--MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSE 546
Query: 1322 DVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR-KKDKEKKE 1380
E+ S G P +E K +G + Q+ P S K K + K
Sbjct: 547 SSSEESSDSSDGEVPTAVAPAQE--KSLGNIL---QAKPTSSPAKGPPQKAGPVAVQVKA 601
Query: 1381 KKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1410
+K S+++S + ++ TA Q
Sbjct: 602 EKPMDNSESSEESSDSADSEEAPAAMTAAQ 631
Score = 41.6 bits (96), Expect = 0.005
Identities = 46/193 (23%), Positives = 81/193 (41%), Gaps = 24/193 (12%)
Query: 1232 EAQVQASVVKV-----LTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1286
+A +QA +V +E E+E + +T K + R + L D P++ ++K
Sbjct: 68 DAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLA-STNSSVLGADLPSSMKEKAK 126
Query: 1287 KKKKLGAGEGGEASVSPEKTSTTSK---GKAKRDKASGD-----VKEKKGKGSLGSQGAK 1338
+ + AG+ G + P T + GK+ R A V E + +GS+ + GA
Sbjct: 127 AETEK-AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 1339 DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1398
+P G V G Q++ S+ SD+ + + K + K +S ESP++
Sbjct: 186 AKP--------GMVSAG-QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 1399 KKKKKKKKTAEQT 1411
K K + T
Sbjct: 237 KAAPAPGKVGDVT 249
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 149 bits (377), Expect = 1e-35
Identities = 286/1305 (21%), Positives = 425/1305 (32%), Gaps = 223/1305 (17%)
Query: 98 TAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSP 157
TAK T +T S L + + K E G P N SP
Sbjct: 662 TAKGTSTYTTTASPFLEGTVSLAPKNHPVKE-------GTLTTLPLVPTASENCPVAPSP 714
Query: 158 RKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV--------SAGQADSSSEDTSSSSDE 209
+ + P A L E + P+ A P ++ A +S +++
Sbjct: 715 QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED 774
Query: 210 TDVEVKASEKILQVRAASAPAK-GTPGKGATPAPPGKAGAVASQTKAGK------PEE-- 260
+ AS K A +P+ G T PP K G+ T G P E
Sbjct: 775 SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS 834
Query: 261 ---DSESSSEESSDSEEET-----PAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
++ S + S DS T P+ K A S G + P KE+P
Sbjct: 835 FLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV-TLPPKETPTPSVVNL 893
Query: 313 PPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA--KESP 370
P K GPA + + ++APA + S + RA AP SP
Sbjct: 894 PFPKEGPA-------------------TPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934
Query: 371 RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG----KS 426
AP PP T P S + S + A A P G S
Sbjct: 935 SPKGAPTPPAATPP-------------SPKGGPATPSPKWAPTPPAATPPSPKGGPATPS 981
Query: 427 PQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTA 486
P+ P P KG GP P G TP A + S +++ +S T
Sbjct: 982 PKGAPTPPAATPPSPKG-GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 487 VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK-AEKPMDNSESSEESSDSADSEE 545
+P + + + PT+ A P K GP +K A P + S + + S +
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
Query: 546 A---PAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSS 602
P A T K L P K P TT +A + G P G T+PA +
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAP----TTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
Query: 603 PAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 662
P+ GG P + + + + G G A KG A+ P G T
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKG-----GLATPSPKGAPTTPAATPPSPKGGLAT 1211
Query: 663 -----APVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA-QVKTSVKKTQAKAN 716
AP P T P + K + S + + + AA P+ + + +
Sbjct: 1212 PSPKGAPTTPAATPP------SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
Query: 717 PAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKA 776
P AA PS KG ++ P +P+ V PP +P+ GPA+ P G
Sbjct: 1266 PPAATPPSLKGGLATP-------PHKGAPNPAVVTPP--SPKG------GPATSPPKGAP 1310
Query: 777 VATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAP 836
AA P GS P K +P A
Sbjct: 1311 TPPAAT----PPSPKGS---------------------------PGTPPPKGAPTPPAV- 1338
Query: 837 TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 896
TPP G A G + S +G P A T + P + P R PA P+
Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398
Query: 897 ---TPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPR 953
+ A +P+KA A+ T +++ S+ + PA +TP V++ A
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA---VTP------VSLKKAPAT 1449
Query: 954 IAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPP 1013
APK GPAT SK +P +T + K A
Sbjct: 1450 SAPKG---------------------GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488
Query: 1014 VARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1073
+ P++ TLPA P S + R P P +K ++
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPAT------- 1541
Query: 1074 DSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL--VEETAAESSEDDVVAPSQSLLSGYM 1131
P+ A + P+P +T + +E A S + +P
Sbjct: 1542 ----------LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP--------- 1582
Query: 1132 TPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAAS 1191
P +TP+ + + + +L P+V+S + K+ P P G +P G +
Sbjct: 1583 -PAVTPSTYKGAPSPKELLIPPAVTSP-SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640
Query: 1192 GTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP---WPLNEAQVQASVVKVLTELLE 1248
TP K +P + T + + + Q G P P +V + T ++
Sbjct: 1641 PVTPSSL---KDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
Query: 1249 QERKKVVDTTKESSR--------KGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEAS 1300
+K T K S+ K LS PA P K K +G +AS
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK--TAKGKDAS 1755
Query: 1301 VSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEEL 1345
SP+ + KA + ++ K S A P L
Sbjct: 1756 HSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
Score = 84.7 bits (208), Expect = 6e-16
Identities = 171/756 (22%), Positives = 274/756 (36%), Gaps = 101/756 (13%)
Query: 100 KATPRLASTNSSVLGADLPSSMKE----KAKAETEKAG--------KTGNSMPHPATGKT 147
K TP L +T S G S KE A + K G K G ++P P T
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
Query: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAA--KPGMVSA---GQADSSSED 202
++ + A P + ++ + + PA + K SA G A SS+
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
Query: 203 TSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDS 262
+ T K QV +S+P K ATPAP G A A P
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAP----ATPAPMG-----APTLPAVIPSSPK 1514
Query: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVA 322
E + SS + P A L S KT PA +P++ A PP T P+
Sbjct: 1515 EVPATPSSRRDPIAPTATLL-----SKKT--------PATLAPKE--ALIPPAMTVPSPK 1559
Query: 323 KAQA--GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPR 380
K A +E + SS+E+ S +P+ PA SP AP PP
Sbjct: 1560 KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK-ELLIPPAVTSPSPKEAPTPPA 1618
Query: 381 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 440
T P+ + + + +S + S L SP + T MG
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSS--------------LKDSPTSPASVTCKMGAT 1664
Query: 441 GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ 500
A P K GP +E + + ES+ PT P +KS
Sbjct: 1665 VPQASKGLPAKKGPTA-------LKEVLVAPAPESTPIITA--PTRKGPQTKKSSATSPP 1715
Query: 501 AKPTSSP---AKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAP------AAMT 551
P S +KGP P + + +K + +++S S AP +T
Sbjct: 1716 ICPDPSAKNGSKGPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774
Query: 552 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA----GSSPAVAG 607
AA + L P++ + + S +AP V T P++ +SP S +A
Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
Query: 608 GTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPV-KGSLGQGTAPVL 666
+ E + V + KS G + +A PV K + G GT
Sbjct: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGT---- 1890
Query: 667 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK 726
++ + + E+Q+ ++++ ++ ++ AAA+ + K Q+++ A +A S
Sbjct: 1891 --ESDSDESVPELEEQDSTQATTQQ--AQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKL 1946
Query: 727 GTISAPGKVVTAAAQAKQRSPSKVKPPV-RNPQNSTVLARGPASVPSVGKAVATAAQAQT 785
G G ++K KP V ++P + T + G A + + + AA +
Sbjct: 1947 GLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKF 2006
Query: 786 GPEEDSGSS----------EEESDSEEEAETLAQVK 811
+ ++ S+ +EES+ EE ET +VK
Sbjct: 2007 KVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVK 2042
Score = 46.6 bits (109), Expect = 2e-04
Identities = 200/920 (21%), Positives = 299/920 (32%), Gaps = 146/920 (15%)
Query: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 435
P +T PA Q Q E + + S AL P +PQ P S
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495
A P P +TP E +SS + +P AP L
Sbjct: 62 NQ------ASPFPSPSTIASTPL----------EVPFPQSSSGT--ALPLGTAPEAPTFL 103
Query: 496 GNILQ----------AKPTSSPA-KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE 544
N++ A P +P KG P + P+A+ A + S S+ +
Sbjct: 104 PNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS-----SAFPPNLL 158
Query: 545 EAPAAMTAAQAKPALKI--PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSS 602
+P ++ A++ + + P + PK ++V P GT +P P S
Sbjct: 159 TSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP--------PCIVS 210
Query: 603 PAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV----KAASVPVKGSL 658
A S T LA+ Q K + S+ +KG +
Sbjct: 211 TVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPV 270
Query: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ--AKAN 716
A L ++ P VT ++K + + S + +P ++S Q +
Sbjct: 271 SPPAALSLSTQSLPVVTS--SQKTAGPNTPPDFPISLGSHLAPLH-QSSFGSVQLLGQTG 327
Query: 717 PAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV--RNPQNSTVLARGPASVPSVG 774
P+A P+ K TIS T A+ QRS V PP+ RN +A P PSV
Sbjct: 328 PSALSDPTVK-TISVDHSS-TGASYPSQRS---VIPPLPSRNEVVPATVAAFPVVAPSVD 382
Query: 775 KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 834
K +T + P SGS + T +K S +A + P
Sbjct: 383 KGPSTISSITCSP---SGSLNVATSFSLSPTTSLILKSSPNATYHYPLVA---QMPVSSV 436
Query: 835 APTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP--NRSPA 892
TP T P A AP P + P N P
Sbjct: 437 GTTPLVVTNPCTIAA------------------APTTTFEVATCVSPPMSSGPISNIEPT 478
Query: 893 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDV--IPATQCLTPGIRTNVVTMPTA 950
PAA A P A+ S + ED+ +P++ + + ++ T+P
Sbjct: 479 SPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVP-- 536
Query: 951 HPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEA 1010
AS+ GA S + ++ +KK+P LPL QAA K S +
Sbjct: 537 -------ASLEGAPFSPAQAGLT------------TKKDPTVLPLVQAAPKNSPSFQSTS 577
Query: 1011 QPPVARTQPSSGV--DSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD 1068
P P + + S LP P S+ G N S
Sbjct: 578 SSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVN-------------------SSA 618
Query: 1069 SEDSSDSSSGSEEDGEGPQGAKSAHTLVG-PTPSRTETLVEETAAESSEDDVVAPSQSLL 1127
S +DS +G + G + + T+ P S V T A+ + S L
Sbjct: 619 SVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLE 678
Query: 1128 SGYMTPGLTPANSQASKAT-PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGG 1186
T L P N + T L P+ S P Q A +L+P+
Sbjct: 679 G---TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSP---QNTCAPLATLVLAPEI-P 731
Query: 1187 KEAASGTTPQKSRKP--KKGAGNPQASTLA-LQSNITQCLLGQPWPLNEAQVQASVVKVL 1243
K S + P P KK G S LA + S+ +C P + A AS L
Sbjct: 732 KSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKEC----PTEDSGASATASSKGTL 787
Query: 1244 TELLEQERKKVVDTTKESSR 1263
T L + V + ++ R
Sbjct: 788 TYLADSPSPLGVSVSPQTKR 807
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 141 bits (355), Expect = 5e-33
Identities = 192/737 (26%), Positives = 279/737 (37%), Gaps = 124/737 (16%)
Query: 1 MAEARKRR----ELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQT 56
MA+A RR +L PL+ L A + + +G A +LLDIY+ W ++
Sbjct: 1 MADAGIRRVVPSDLYPLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLKS 60
Query: 57 SEL-GRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGA 115
+++ RK +A A +AKK S + +SSEEEEE + AK A G
Sbjct: 61 AKVPERKLQANGPVAKKAKKKASSS--DSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGK 118
Query: 116 DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
+ + + E+ + P + K+P K A+ S + + S +E
Sbjct: 119 AAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDE 178
Query: 176 ----------------EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEK 219
+ P A A P ++ G+A SSS +SSSS D E
Sbjct: 179 PPKNQKPKITPVTVKAQTKAPPKPARAAP-KIANGKAASSSSSSSSSSSSDDSE------ 231
Query: 220 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 279
+ +AA+ P K P K P KA A P S SS + SSD EEE
Sbjct: 232 --EEKAAATPKKTVPKKQVVAKAPVKA--------ATTPTRKSSSSEDSSSDEEEE---Q 278
Query: 280 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEE 339
K ++ K G S V SAP P+K PP K AV K Q + EDS S+
Sbjct: 279 KKPMKNK-PGPYSSVPPPSAP---PPKKSLGTQPPKK---AVEKQQPVESSEDSSDESDS 331
Query: 340 SDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSR 399
S EE+ P P K K PP K+ +S
Sbjct: 332 SSEEEKKP-----------------PTKAVVSKATTKPPP------------AKKAAESS 362
Query: 400 SSSEESDSDREALAAMNAAQVKPLG--KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 457
S S +SDS + + A KP G K+ KPA T + A P P G
Sbjct: 363 SDSSDSDSSED-----DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 458 SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGP 517
+ + DS SS EESS S + + VA + K+ S PAK PQ +
Sbjct: 418 TRKA-----DSSSSEEESSSSEEEKTKKMVATTKPKATAK----AALSLPAKQAPQGS-- 466
Query: 518 VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTNT 573
SS+ S S++ EE + +A + KP P A KK
Sbjct: 467 ------------RDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKA 514
Query: 574 TASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES-DSEEEKTGLA 632
+S + + K SP +P G + A++ +++ S + EEEK A
Sbjct: 515 ESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAA 574
Query: 633 VTVGQAKSVGKGLQ---VKAASVPVKGSLGQGTAPVLPGK-------TGPTVTQVKAEKQ 682
V V ++ S+ K Q K A P + T P + + P + E +
Sbjct: 575 VVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIE 634
Query: 683 EDSESSEEESDSEEAAA 699
DS ++ D++ AA
Sbjct: 635 VDSRVADNSFDAKRGAA 651
Score = 140 bits (353), Expect = 9e-33
Identities = 202/765 (26%), Positives = 282/765 (36%), Gaps = 193/765 (25%)
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASA 228
L S E + A G AK A SSS+ SS +E +V+ ++K A+
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKA----SSSDSEDSSEEEEEVQGPPAKK------AAV 107
Query: 229 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKAS 288
PAK PPGKA A AS++ SSSEESSD ++E K +Q
Sbjct: 108 PAK------RVGLPPGKAAAKASES----------SSSEESSDDDDEEDQKKQPVQKGVK 151
Query: 289 GKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 348
P+ AA APP K S S +S SE+E P
Sbjct: 152 ----------------PQAKAAKAPPKKA--------------KSSDSDSDSSSEDEPPK 181
Query: 349 QAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 408
KP V+A + ++P K A AP G AA+ S SSS++S+ +
Sbjct: 182 NQKPKITPVTVKAQT----KAPPKPARAAPKIANGKAASS----SSSSSSSSSSDDSEEE 233
Query: 409 REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 468
+ A K + VK A+T P K + S+ EE+
Sbjct: 234 KAAATPKKTVPKKQVVAKAPVKAATT-------------PTRKSSSSEDSSSD---EEEE 277
Query: 469 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPM 528
+ ++ VP AP +KSLG PP+KA V+ ++P+
Sbjct: 278 QKKPMKNKPGPYSSVPPPSAPPPKKSLGT------------QPPKKA------VEKQQPV 319
Query: 529 DNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA 588
++SE S + SDS+ EE K P TKA K T K P +
Sbjct: 320 ESSEDSSDESDSSSEEE--------------KKPPTKAVVSKATT----KPPPAK----- 356
Query: 589 PRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVK 648
+ AE SS S +SDS E+ + G K+ V
Sbjct: 357 ----------------------KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVT 394
Query: 649 AASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSV 708
S VK + AP P G + KA DS SSEEES S E + V T+
Sbjct: 395 TKSPAVKPA----AAPKQPVGGGQKLLTRKA----DSSSSEEESSSSEEEKTKKMVATTK 446
Query: 709 KKTQAKA--NPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARG 766
K AKA + A +AP S+ ++ + ++ S S VK + PQ
Sbjct: 447 PKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVK---KKPQK------- 496
Query: 767 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPA 826
+ G A + A A+ G E S SS + SEEE E L
Sbjct: 497 ----VAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL-----------------KG 535
Query: 827 KESPRKGAAPTPPGKTGPSA--AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIF 884
K SPR P P G SA AQ GK + +SEE + + + A V S
Sbjct: 536 KGSPR----PQAPKANGTSALTAQNGK---AAKNSEEEEEEKKKAAVVVSKSGSLKKRKQ 588
Query: 885 VDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDV 929
+ + P A + Q +T K + E A S +E++
Sbjct: 589 NEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEI 633
Score = 124 bits (311), Expect = 6e-28
Identities = 163/630 (25%), Positives = 244/630 (38%), Gaps = 122/630 (19%)
Query: 788 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA 847
++ + SS+ E SEEE E Q P+ K A PAK PPGK
Sbjct: 79 KKKASSSDSEDSSEEEEEV--QGPPAKK------AAVPAKR------VGLPPGKA----- 119
Query: 848 QAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 907
A K +S SS E SD D E D + P P A + P
Sbjct: 120 -AAKASESSSSEESSDDDDEE-----------------DQKKQPVQKGVKPQAKAAKAPP 161
Query: 908 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPT-AHPRIAPKASMAGASSS 966
+KA++S+S + SSS + ++ P +T +T P A P+IA + + +SSS
Sbjct: 162 KKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSS 221
Query: 967 KESSRISDGKKQEGPATQ---VSKKNP-ASLPLTQAALKVLAQKASEAQPPVARTQPSSG 1022
SS D ++++ AT V KK A P+ A +SE +
Sbjct: 222 SSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKP 281
Query: 1023 VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEED 1082
+ + G + P S K K E QQ ESS+DS D SDSSS EE+
Sbjct: 282 MKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPV---ESSEDSSDESDSSS--EEE 336
Query: 1083 GEGPQGAKSAHTLVGPTPSR--TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1140
+ P A + P P++ E+ + + ++SSEDD APS+ G T +S
Sbjct: 337 KKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE-APSKPA-------GTTKNSS 388
Query: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1200
T K SP+V A K G Q+ ++A + E S ++ ++ K
Sbjct: 389 NKPAVTTK---SPAVKPAAAPKQPVGGGQKLLTRKA------DSSSSEEESSSSEEEKTK 439
Query: 1201 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1260
P+A+ A L K+ +++
Sbjct: 440 KMVATTKPKATAKAA-------------------------------LSLPAKQAPQGSRD 468
Query: 1261 SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKAS 1320
SS S S ++ +T +S KKK GG A P K ++ KGKA+ +S
Sbjct: 469 SSSDSDSS-----SSEEEEEKTSKSAVKKKPQKVAGGAA---PSKPASAKKGKAESSNSS 520
Query: 1321 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEG-GDQSNPKSKKEKKKSDKRKKDKEKK 1379
S E EEE KG G+ ++N S + K +E++
Sbjct: 521 -------------SSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEE 567
Query: 1380 EKKKKAKKASTKDSESPSQKKKKKKKKTAE 1409
E+K KKA+ S+S S KK+K+ + E
Sbjct: 568 EEK---KKAAVVVSKSGSLKKRKQNEAAKE 594
Score = 118 bits (295), Expect = 5e-26
Identities = 150/612 (24%), Positives = 235/612 (38%), Gaps = 97/612 (15%)
Query: 823 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 882
L AK RK A P K A + +DS EE AAV + +V PP
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG 117
Query: 883 IFV-------------------DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE 923
D + P P A + P+KA++S+S + SSS +
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED 177
Query: 924 SEDEDVIPATQCLTPGIRTNVVTMPT-AHPRIAPKASMAGASSSKESSRISDGKKQEGPA 982
++ P +T +T P A P+IA + + +SSS SS D ++++ A
Sbjct: 178 EPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAA 237
Query: 983 T---QVSKKN-PASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQST 1038
T V KK A P+ A +SE + + + G + P S
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSA 297
Query: 1039 SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGP 1098
K K E QQ ESS+DS D SDSS SEE+ + P A + P
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPV---ESSEDSSDESDSS--SEEEKKPPTKAVVSKATTKP 352
Query: 1099 TPSR--TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVS 1156
P++ E+ + + ++SSEDD APS+ G T +S T K SP+V
Sbjct: 353 PPAKKAAESSSDSSDSDSSEDD-EAPSK-------PAGTTKNSSNKPAVTTK---SPAVK 401
Query: 1157 STLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQ 1216
A K G Q+ ++A + E S ++ ++ K P+A+ A
Sbjct: 402 PAAAPKQPVGGGQKLLTRKA------DSSSSEEESSSSEEEKTKKMVATTKPKATAKA-- 453
Query: 1217 SNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGD 1276
L+ +Q + D++ +S E + K S
Sbjct: 454 -------------------------ALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTS-- 486
Query: 1277 QPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEK-KGKGSLGSQ 1335
++ KK +K+ G S +K S + D +S + +EK KGKGS
Sbjct: 487 ----KSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGS---- 538
Query: 1336 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKK-----DKEKKEKKKKAKKAST 1390
P + K GT Q+ +K +++ +++KK K KK+K +A+
Sbjct: 539 -----PRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA- 592
Query: 1391 KDSESPSQKKKK 1402
K++E+P KK K
Sbjct: 593 KEAETPQAKKIK 604
Score = 103 bits (256), Expect = 2e-21
Identities = 166/703 (23%), Positives = 274/703 (38%), Gaps = 125/703 (17%)
Query: 719 AARAPSAKGTISAP--GKVVTAAAQAKQRSPSKVKPPVRNP--QNSTVLARGPASVPSVG 774
+A+ P K + P K A+ + S+ + V+ P + + V A+ P G
Sbjct: 60 SAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPP--G 117
Query: 775 KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 834
KA A A++ S SSEE SD ++E + Q G Q +AA AP K++
Sbjct: 118 KAAAKASE--------SSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK---- 165
Query: 835 APTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA---AVTSAQVIKPPLIFVDPNRSP 891
DS SSSE+ + P AQ PP P
Sbjct: 166 ---------------SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPP--------KP 202
Query: 892 AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP--T 949
A A A +AAS+ S S++ SSSS+ +E+ AT T + V P
Sbjct: 203 ARAAPKIANGKAASS------SSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKA 256
Query: 950 AHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL-AQKAS 1008
A +S +SS +E + K + GP + V P S P + +L +KA
Sbjct: 257 ATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVP---PPSAPPPKKSLGTQPPKKAV 313
Query: 1009 EAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD 1068
E Q PV ++ SS +S + P + +V +K T K P ++A ++ S D
Sbjct: 314 EKQQPVESSEDSSD-ESDSSSEEEKKPPTKAVVSKATT-----KPPPAKKAAESSSDSSD 367
Query: 1069 SEDSSDSSSGSEEDGEGPQGA------------KSAHTLVGPTPSRTETLVEETAAESSE 1116
S+ S D + S+ G + K A P + L + + SSE
Sbjct: 368 SDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSE 427
Query: 1117 DDVVAPSQSLLSGYMTPGLTPANSQASKATP--------KLDSSPSVSSTLAAKDDPDGK 1168
++ + + + A ++A+ + P + SS S SS+ +++ K
Sbjct: 428 EESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSK 487
Query: 1169 Q--EAKPQQAAGMLSP------KTGGKEAASGTTPQKSRKPK----KGAGNPQASTLALQ 1216
+ KPQ+ AG +P K G E+++ ++ S + + KG G+P+ A +
Sbjct: 488 SAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQ--APK 545
Query: 1217 SNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGD 1276
+N T L Q K E E+++K V +K S K KRK +
Sbjct: 546 ANGTSALTAQ---------NGKAAKNSEEEEEEKKKAAVVVSKSGSLK-----KRKQNEA 591
Query: 1277 QPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQG 1336
A TP++KK + + +T K K +AS + + +
Sbjct: 592 AKEAETPQAKK-------------IKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSR 638
Query: 1337 AKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKK 1379
D + + G + G+++N K K KS + +K K+K+
Sbjct: 639 VADNSFDAKRGAAG--DWGERANQVLKFTKGKSFRHEKTKKKR 679
Score = 54.3 bits (129), Expect = 8e-07
Identities = 82/377 (21%), Positives = 143/377 (37%), Gaps = 81/377 (21%)
Query: 1048 LRKPKLPE--------VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL--VG 1097
L+ K+PE V + K SS DSEDSS+ EE+ +GP K+A VG
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEE----EEEVQGPPAKKAAVPAKRVG 113
Query: 1098 PTPSRTETLVEETAA--ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSV 1155
P + E+++ ESS+DD + + G+ P ++A+KA PK S
Sbjct: 114 LPPGKAAAKASESSSSEESSDDD---DEEDQKKQPVQKGVKP-QAKAAKAPPKKAKSSDS 169
Query: 1156 SSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLAL 1215
S +++D+P Q+ K ++P T +A + P+ +R K A AS+
Sbjct: 170 DSDSSSEDEPPKNQKPK-------ITPVT--VKAQTKAPPKPARAAPKIANGKAASS--- 217
Query: 1216 QSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG 1275
++ SS +S + K
Sbjct: 218 ----------------------------------------SSSSSSSSSSDDSEEEK--- 234
Query: 1276 DQPAARTPRSK-KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1334
AA TP+ KK++ A +A+ +P + S++S+ + ++ K G S
Sbjct: 235 ---AAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS 291
Query: 1335 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSE 1394
P + K +GT + E + + D +E+KK KA +
Sbjct: 292 VPPPSAPPPK--KSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 1395 SPSQKKKKKKKKTAEQT 1411
+ KK + +++ +
Sbjct: 350 TKPPPAKKAAESSSDSS 366
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 125 bits (315), Expect = 2e-28
Identities = 297/1442 (20%), Positives = 497/1442 (34%), Gaps = 207/1442 (14%)
Query: 80 DPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSM 139
D IS SE+S+EE T K + G P ++ K ++ G + +
Sbjct: 177 DLISDSEASQEE------TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
Query: 140 PHPATGKTVANLLSGK---SPRKSAEPSANTTLVSETEE-------EGSVPAF------- 182
T K++++ K P + +P T +T+ + S P
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVR 290
Query: 183 GAAAKPGMVSAG----QADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGA 238
G + KP + S Q + + + + ++ Q + P PG
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 239 TPA-PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT------ 291
P PPG A KP S + SS E P KAL Q GKT
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSS----EQPGPKALAQPPGVGKTPAQQPG 406
Query: 292 ------SQVGA----ASAPAKESPRKGAAPA--PPGKTGPAVAKAQ-AGKREEDSQSS-- 336
QVG A P +SP K P P + GP AQ AG + +Q +
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 337 ----SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA-AQVQV 391
S+ + P Q P+ PQ ++ P + P G+ PP++ GPA + Q
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKPSPQQP 524
Query: 392 GKQEEDSRSSSEESDSDREALAAMNAAQ--VKPLGKSPQVKPASTMGMGPLGKGAGPVPP 449
G + S+ S ++ A +AQ KP+ ++ KP + P K PP
Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ----PP 580
Query: 450 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA------------------- 490
+ P T + E E+++ ++ E T V
Sbjct: 581 SQGLPKT-ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLN 639
Query: 491 --QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 548
+++LG L P+S P K PV K + + D+A ++
Sbjct: 640 CQMKRALGGDLAPVPSSPQ---PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSK 696
Query: 549 AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR--VGTQAPRKAGTATSPAGSSPAVA 606
A + P +K P P +A AK P + AP K + S +P
Sbjct: 697 APEPKKPPPLVKQPTLHGSP-----SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751
Query: 607 GGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL 666
++P +++ S T + + +S + + + P+K + +
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE----EKTTPPLKTDSAKPSQSFP 807
Query: 667 PG--KTGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKANPAAA 720
P K P ++ DS+ S E+ P Q K KK Q K +P
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 721 RAPSAKGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA 778
P KG+ + PG TA Q+SP + R N + P S P+
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT------ 921
Query: 779 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT- 837
T + TG G+S S + T Q P H AP K++P PT
Sbjct: 922 TPQETVTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQPPTS 976
Query: 838 --PPGKTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRS 890
PP TG P+ + K++ ++E+ + E V + K P P +
Sbjct: 977 QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKD 1032
Query: 891 PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM--- 947
A P +A + K+ EST +E P + V +
Sbjct: 1033 SKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGF 1092
Query: 948 -PTAH-PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ 1005
PT H I + + S ++ D +K PA K +P +P ++ K
Sbjct: 1093 NPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-PAPSGPKASPMPVPTESSSQKTAVP 1151
Query: 1006 ---KASEAQPPVARTQPSSGVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPEVQQA 1059
K + Q +T+ + V ++ P T+ Q + +KL K K +Q+
Sbjct: 1152 PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211
Query: 1060 TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE--TAAESSED 1117
PE + EE+ + K PTP + L E +A E +
Sbjct: 1212 KPLPE---------EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKH 1262
Query: 1118 DVVAPSQSLLSGYMTPGLTPANSQASKATP-KLDSSPSVS----------STLAAKDDPD 1166
D++ + + + P Q K K++ PS + +T K+ P
Sbjct: 1263 DLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQ 1322
Query: 1167 GKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQ 1226
AKP Q KT ++ S T+ + K +G + S+ + S++ + +
Sbjct: 1323 PPCTAKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPS 1379
Query: 1227 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAA 1280
P +E + + K D+ + S S KL + A+
Sbjct: 1380 LIPTDEKDILKGLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQAS 1425
Query: 1281 RTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDE 1340
K +KK E VSPE+ K ++ + + E++ K S ++E
Sbjct: 1426 TLADEKSEKKTQPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEE 1474
Query: 1341 PEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKK 1400
++ +K Q P SK K+KS+ ++E +++S ++ Q+K
Sbjct: 1475 RKDTFKKD------SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK 1528
Query: 1401 KK 1402
++
Sbjct: 1529 RR 1530
Score = 100 bits (250), Expect = 8e-21
Identities = 309/1435 (21%), Positives = 490/1435 (34%), Gaps = 294/1435 (20%)
Query: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGT 233
E EG AAA G ++G A S S + E D+ + E+ Q+ A + A+G
Sbjct: 8 EGEGLPEGLAAAAAAGGGASG-AGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGL 66
Query: 234 PGKGATPA-----------------PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE- 275
P PA PP ++G + +P S+S + ++ SE++
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGL-SKSRTTDTFRSEQKL 125
Query: 276 ---TPAAKALLQAKA-------------SGKTSQVGAASAPA------------------ 301
+P+ +L ++K+ G S+V A SA +
Sbjct: 126 PGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEAS 185
Query: 302 ------------KESPRKGAAPAPPGKTGP--AVAKAQAGKREEDSQSSSEESDSEE--- 344
KE + PP + P + K Q R+ Q + +S S +
Sbjct: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245
Query: 345 ----EAPAQAKP-----------SGKAPQVRAASAPAKESP----RKGAAPAPPRKTGPA 385
+ P KP K P R AS P + + P+ P + P
Sbjct: 246 KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 386 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP-QVKPASTMGMGPLGKGA 444
Q GK + E+S A + KPL + P VKP + P G
Sbjct: 306 IQQPTPGKPPA-QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP----VQPPGTTK 360
Query: 445 GPVPPGKVGPATPSA-QVGKWEEDSESSSEESSDSSDGEVPT-------AVAPAQEKSLG 496
P P +GPA P A Q G + SE ++ G T A P Q+
Sbjct: 361 PPAQP--LGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418
Query: 497 NILQAKP-------TSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
L +P P K P Q+ GP + + P S + PA
Sbjct: 419 KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAK 478
Query: 550 MTAAQAKPALKIPQTKACPK-KTNTTASAKVAPVRVG--TQAPRKAGTATSPAGSSPAVA 606
Q PA PQ K + S K P + G +P++ G+ P+ +
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 607 GGTQRPAEDSSSSEESDSEEEKTGL-------AVTVGQAKSVGKGLQVKAA--------- 650
Q+P+ S+++S +TG V+ + +GL
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL 598
Query: 651 -SVPVKGSLG-----QGTAPVLPG-KTGPTVTQVK---------------------AEKQ 682
VP K + Q T L G P +T+VK + Q
Sbjct: 599 LHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658
Query: 683 EDSESSEEESDSEEAAASPAQVKTSVKKTQA-----------KANPAAARAPSAKGTISA 731
+++ + S + +SP +TS KK A K P + P+ G+ SA
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 732 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKA---VATAAQAQTGPE 788
K A + +P K +P V + Q+ +A P + K + +++ A T P
Sbjct: 719 KAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP- 776
Query: 789 EDSGSSEEESDSEEEAE---TLAQVKPSGKTHQIRAALAP--AKESPRKGAAPTPPGKTG 843
D SS+ +S +EE+ KPS ++P +K PR + G
Sbjct: 777 -DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835
Query: 844 PSAAQAG-KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ 902
PS+ G KQ D EE +A ++ KP P SP P P Q
Sbjct: 836 PSSESKGQKQVDPVQKKEEPK---KAQTKMSPKPDAKPM-----PKGSPTPPGPRPTAGQ 887
Query: 903 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 962
TP+++ + +R S P +Q TP + K G
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP------------QETVTGKLFGFG 935
Query: 963 ASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSG 1022
AS ++S + Q GP +Q P + Q + +QPP ++ P S
Sbjct: 936 ASIFSQASNLISTAGQPGPHSQSGPGAP------------MKQAPAPSQPPTSQGPPKS- 982
Query: 1023 VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA--TKAPESSDDSEDSSDSSSGSE 1080
G P +S V+ + + P+ +QA K E+ DS S +
Sbjct: 983 ----TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTA 1038
Query: 1081 EDGEGPQGAKSAHTL-VGPTPSRTETLVEETAAESSED--------DVVAPSQSLLSGYM 1131
E PQ A L P P T L + S+D + +L
Sbjct: 1039 E----PQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094
Query: 1132 TPGLTP------ANSQASKATP-------KLDSSPS--VSSTLAAKDDPDGKQEAKPQQA 1176
TP LT N Q +A K+ +PS +S + + ++ A P Q
Sbjct: 1095 TPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQV 1154
Query: 1177 AGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQ 1236
+ + K A +K ++ TL+++ Q E++++
Sbjct: 1155 KLVKKQEQEVKTEAEKVILEKVKE-----------TLSMEKIPPMVTTDQ--KQEESKLE 1201
Query: 1237 ASVVKVLTEL--LEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAG 1294
L E L +E+K + + K S E +K L +P TP KK
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRS----EEKKPLLEEKKP---TPEDKK------- 1247
Query: 1295 EGGEASVSPE-KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVE 1353
+ PE KTS + K K+ + E+K +G + + + E ++ K G
Sbjct: 1248 ------LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQPQTKMEGLPS 1300
Query: 1354 GGDQSNPKSKKEKKKSDKRK-------KDKEKKEKKKKAKKASTKDSESPSQKKK 1401
G QS PK + K+ K + K + + K+K +K K S SQ+ K
Sbjct: 1301 GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355
Score = 93.6 bits (231), Expect = 1e-18
Identities = 212/999 (21%), Positives = 338/999 (33%), Gaps = 181/999 (18%)
Query: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD-- 341
+A G+ G A+A A GA P+ AG + SQ S EE
Sbjct: 4 EASLEGEGLPEGLAAAAAAGGGASGAG-------SPSHTAIPAGMEADLSQLSEEERRQI 56
Query: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 401
+ + AQ P G P AA +P+ ++ + PP+++G G+ + S
Sbjct: 57 AAVMSRAQGLPKGSVPPA-AAESPSMHRKQELDSSHPPKQSGRPP---DPGRPAQPGLSK 112
Query: 402 SEESDSDREALAAMNAAQVKPLGKSPQV----KPASTMGMGPLGKGAGPVPPGKVGPATP 457
S +D+ R ++ K G+SP + S + K + + PG +
Sbjct: 113 SRTTDTFR--------SEQKLPGRSPSTISLKESKSRTDLKEEHKSS--MMPGFLSEVNA 162
Query: 458 ----SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 513
S+ V K+ S E+S + V Q K G I++ P K P+
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG-IIKPPLQQQPPKPIPK 221
Query: 514 KAGPVAVQVKAEKPMDNSESSEE-SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 572
+ GP P+ + + SS + ++ T + + PQT
Sbjct: 222 QQGP------GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ 275
Query: 573 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 632
AS QA G + P+ SP+ Q+P +++ E+ + G A
Sbjct: 276 RDASRPQTK-----QADIVRGESVKPSLPSPSKPP-IQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 633 VTVGQAKSVGKGLQVKAASV--PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEE 690
Q + K L + +V PV+ PG T P + K ++ E
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQP----------PGTTKPPAQPLGPAKPPAQQTGSE 379
Query: 691 ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 750
+ SE+ V KT A+ P A+ P+ + P A Q +SP+K
Sbjct: 380 KPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQQVGTPKP-----LAQQPGLQSPAKA 433
Query: 751 KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS--------SEEESDSEE 802
P + P V GP +P+ + QTGP + ++ ++
Sbjct: 434 PGPTKTP----VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
Query: 803 EAETLAQVKPS----GKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSS 858
+ KP G T PAK SP++ + PP + SA + +Q S
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP---SP 546
Query: 859 SEESDSDGEAPAAVT-SAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTA 917
++ S P + T S + ++PP + + P+ +T E
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
Query: 918 RSSSSESEDEDVIPATQCLTPGIRTN--------------------------VVTMPTAH 951
++ +E + T C G N V + P
Sbjct: 607 FNTCTECQ------TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
Query: 952 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSK----KNPASLPLTQAALKVLAQKA 1007
+ AP + + S S + + KK P +SK K P PL + + A
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP--PLVKQPTLHGSPSA 718
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
QPP A DS P P S Q K KPK P++ + T SS
Sbjct: 719 KAKQPPEA--------DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLL 1127
+ D S S+ ++ EE + D PSQS
Sbjct: 771 SATTKPDIPS-----------------------SKVQSQAEEKTTPPLKTDSAKPSQSF- 806
Query: 1128 SGYMTPGLTPANSQASKATPKLDSS--------PSVSSTLAAKDDPDGKQEAKPQQAAGM 1179
P + SKA P+ S PS S + DP K+E +P++A
Sbjct: 807 ----PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE-EPKKAQTK 861
Query: 1180 LSPKTGGKEAASGT---------------TPQKSRKPKK 1203
+SPK K G+ TPQ+S KP++
Sbjct: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Score = 88.2 bits (217), Expect = 5e-17
Identities = 254/1255 (20%), Positives = 435/1255 (34%), Gaps = 275/1255 (21%)
Query: 62 KRKAEEDAALQAKKTRVSDPISTSESSE----EEEEAEAETAKATPRLASTNSSVLGADL 117
K K +A +K +P SE + +++ + + K T L S++S+ D+
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 118 PSS-MKEKAKAETEKAGKTGNSMPH---PATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
PSS ++ +A+ +T KT ++ P P TG+ V+ S PR P++++ ++S
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR----PASDSKIISH- 833
Query: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGT 233
PG S + + + + K S K A KG+
Sbjct: 834 --------------PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK----PDAKPMPKGS 875
Query: 234 PGKGATPAPPGKAG-AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292
P P P AG V + ++ KP+E S S + + Q +GK
Sbjct: 876 P---TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932
Query: 293 QVGAAS-APAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK 351
GA+ + A P P ++GP QA + S K
Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP-----------K 981
Query: 352 PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 411
+G+AP A S P K+ + AA K P A Q K+ E + DS
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAA----EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037
Query: 412 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-------------PS 458
A L KSP KP ST + G P T P+
Sbjct: 1038 AEPQKAVLPTKLEKSP--KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPT 1095
Query: 459 AQVGKWEE--DSESSSEESSDSSDGEV-PTAVAPAQEKSLGNILQAKPTSSPAKGPPQ-- 513
+ + +E ++ + G++ AP+ K+ + + +S PPQ
Sbjct: 1096 PHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155
Query: 514 --KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP--K 569
K V+ +AEK + E+ ++ E+ P +T Q + K+ + KA +
Sbjct: 1156 LVKKQEQEVKTEAEKVI-----LEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQE 1210
Query: 570 KTNTTASAKVAP----VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAE---DSSSSEES 622
K K+ P +R + P +P T P E D S+
Sbjct: 1211 KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQ 1270
Query: 623 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQ 682
+EE+ G + GK Q K +P GT LP + T +K + Q
Sbjct: 1271 IAEEKLEGRVAP--KTVQEGKQPQTKMEGLP------SGTPQSLPKEDDKTTKTIKEQPQ 1322
Query: 683 EDSESSEEESDSEEAAASPAQVKTSVKKTQA---KANPAAARAPSAKGTISAPGKVVTAA 739
A P QV+ +KT+ K++ ++++ P + +S G
Sbjct: 1323 PP------------CTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGI 1370
Query: 740 AQAKQRSPSKVKPPVRN---------------PQNSTVLARGPASVPSVGKAVATA---- 780
+ + PS + ++ P + + LA+ ++V S+ +A A+
Sbjct: 1371 SSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430
Query: 781 -AQAQTGPEEDSG--------------------SSEEESDSEEEAETL-----AQVKPSG 814
++ +T P E S S EE +S+EE + Q PS
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490
Query: 815 KTHQIRAALAP-----------AKESPRKGAAPTPPGK----TGPSAAQAGKQDDSGSSS 859
K H+ ++ +ES +P P K G S++ KQ+DS S
Sbjct: 1491 KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSG 1550
Query: 860 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 919
EE D I+ +I + + +G S + ++ S
Sbjct: 1551 EEED-------------FIRKQIIEMSADEDASG-----------SEDDEFIRNQLKEIS 1586
Query: 920 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 979
SS+ES+ ++ +T G H R+ K+S S +++ R ++
Sbjct: 1587 SSTESQKKEETKGKGKITAG----------KHRRLTRKSS---TSIDEDAGRRHSWHDED 1633
Query: 980 GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTS 1039
A S + LK K+ E++ V G T+ S +
Sbjct: 1634 DEAFDESPE-----------LKYRETKSQESEELVV---TGGGGLRRFKTIELNSTIADK 1679
Query: 1040 VQAKGTNKL------RKPKLPEVQQATKAPE----------------------SSDDSED 1071
A+ + K +P+L E++ T +PE +S S D
Sbjct: 1680 YSAESSQKKTSLYFDEEPEL-EMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLD 1738
Query: 1072 SSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYM 1131
SS S + GE Q K+ H GP + T +SSE++ + + LL
Sbjct: 1739 EDSDSSPSHKKGESKQQRKARHRPHGP--------LLPTIEDSSEEEELREEEELL---- 1786
Query: 1132 TPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPD----GKQEAKPQQAAGMLSP 1182
+ + +++ SS+ +K D D ++ +P+ LSP
Sbjct: 1787 ---------KEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSP 1832
Score = 49.3 bits (116), Expect = 3e-05
Identities = 153/791 (19%), Positives = 270/791 (34%), Gaps = 124/791 (15%)
Query: 197 DSSSEDTSS-------SSDETDVEVKASEKILQ-----VRAASAPAKGTPGKGATPAPPG 244
+SSS+ T+ E +V+ +A + IL+ + P T + +
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201
Query: 245 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 304
K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEK------------------ 1239
Query: 305 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP----SGKAPQVR 360
P P K AK A + ++ S+ +EE+ + P GK PQ +
Sbjct: 1240 -----KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTK 1294
Query: 361 AASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDR 409
P+ K + P PP P QV+ GK++ + ++ S +
Sbjct: 1295 MEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQ 1352
Query: 410 EALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSE 469
+ KSPQ + + G +P + P + ++D
Sbjct: 1353 QP-------------KSPQGLSDTGYSSDGISSSLGEIP--SLIPTDEKDILKGLKKD-- 1395
Query: 470 SSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMD 529
S S+ESS SS ++ E ++ +IL+A+ ++ + +K P V + K +
Sbjct: 1396 SFSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQE 1450
Query: 530 NSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 589
++S E+ + SEE + + K K + P + ++ + P
Sbjct: 1451 KTQSLSETLEITISEE-EIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREP 1509
Query: 590 RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDSEEEKTGLAVTVGQAKSV 641
+ +S + +SP V +R + SSSS+E S EE+ + A
Sbjct: 1510 YDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADED 1568
Query: 642 GKG-----------LQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDS--ESS 688
G ++ +++ K +G + GK + ED+ S
Sbjct: 1569 ASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHS 1628
Query: 689 EEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAKGTISAPGKVVTAAAQAK 743
+ D E SP K +++ R + + + K ++Q K
Sbjct: 1629 WHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKK 1688
Query: 744 -----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 798
P + + G +S+ + T+ + + +EDS SS
Sbjct: 1689 TSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHK 1748
Query: 799 DSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPPGKTGPSAAQAGKQDDSG 856
E + + A+ +P G L P E S + + +Q
Sbjct: 1749 KGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRK 1801
Query: 857 SSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASEST 916
SSS++S D + A + K P N SP A+ + + A+ + S +
Sbjct: 1802 SSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTEELRQAAEMEELHRSSCS 1857
Query: 917 ARSSSSESEDE 927
S S ES+ E
Sbjct: 1858 EYSPSIESDPE 1868
Score = 49.3 bits (116), Expect = 3e-05
Identities = 86/422 (20%), Positives = 160/422 (37%), Gaps = 60/422 (14%)
Query: 61 RKRKAEEDAALQAKKTRVSDP----ISTSESSEEEEEAEAETAKATPRLASTNSSVLGAD 116
+K E+ L KT + + S+ EE+ E A T + + +
Sbjct: 1239 KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEG- 1297
Query: 117 LPSSMKEKAKAETEKAGKTGNSMPHP---------ATGKTVANLLSGKSPRKSAEPSANT 167
LPS + E +K KT P P GK KS S++ +
Sbjct: 1298 LPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Query: 168 TLVSET--------EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASE- 218
+S+T G +P+ + ++ + DS S+++S SS +++++
Sbjct: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL 1417
Query: 219 KILQVRAAS----APAKGTPGKGATPAPP---GKAGAVASQTKAGKPEEDSESSSEE--- 268
IL+ +A++ K T +P P K +++ + EE+ + S EE
Sbjct: 1418 SILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKD 1477
Query: 269 --SSDSEEETPAAKALLQAKASGKTSQVGAASAP---AKESPRKGAAPAPPGKTGPAVAK 323
DS+++ P++K + S + P +ES +P P K +V
Sbjct: 1478 TFKKDSQQDIPSSKD--HKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGS 1535
Query: 324 AQAGK-REEDSQSSSEESD----------SEEEAPAQAKPSGKAPQVRAASAPAKESPRK 372
+ + + ++EDSQ S EE D ++E+A Q++ S+ + ES +K
Sbjct: 1536 SSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISS-STESQKK 1594
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
+ ++ GK +R SS D D + + + +SP++K
Sbjct: 1595 --------EETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYR 1646
Query: 433 ST 434
T
Sbjct: 1647 ET 1648
Score = 35.0 bits (79), Expect = 0.51
Identities = 91/409 (22%), Positives = 149/409 (36%), Gaps = 47/409 (11%)
Query: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGT---PGKGATPAP 242
A PG++S T S TDV VK EK + R++ A +G G+ T P
Sbjct: 3386 APPGILS----------TVSEIPLTDVVVK-EEKQPKKRSSGAKVRGQYDDMGENMTDDP 3434
Query: 243 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS-QVGAASAPA 301
V S + D E +++ S S + K S TS Q
Sbjct: 3435 RSFKKIVDSGVQT-----DDEDATDRSYVSRRR--------RTKKSVDTSVQTDDEDQDE 3481
Query: 302 KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG--KAPQV 359
+ P + A GK G ++ +A K + S+ SS + E Q +P G + P +
Sbjct: 3482 WDMPTRSRRKARVGKYGDSM--TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSI 3539
Query: 360 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 419
RA E + +AP K G Q E DS + S + S
Sbjct: 3540 RARVDAKVEIIKHISAPEKTYKGGSLGCQT-----EADSDTQSPQYLSATSPPKDKKRPT 3594
Query: 420 VKPLGKSPQVKPASTMGMGPLGKGA-----GPVPPGKVGPATPSAQVGKWEEDSESSSEE 474
+G S ++ ST+ + P + P+ P G A SA V + + S +
Sbjct: 3595 PLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQ 3654
Query: 475 SSDSSD-GEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 530
D +VP A A ++S+ + PT+ + P + K + M +
Sbjct: 3655 KVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQY-TEGYTTKGSQTMTS 3713
Query: 531 SESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV 579
S + ++ + + T Q+ + ++ +TNT A AK+
Sbjct: 3714 SGAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKI 3762
Score = 30.8 bits (68), Expect = 9.6
Identities = 76/436 (17%), Positives = 155/436 (35%), Gaps = 67/436 (15%)
Query: 24 VRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPIS 83
+ ++++ KE+S F+ T + Y +++SE E++ + +K R S S
Sbjct: 1487 IPSSKDHKEKSE---FVDDITTRREPYDSVEESSE-------SENSPVPQRKRRTSVGSS 1536
Query: 84 TSESSEEEE-----EAEAETAKATPRLASTNSSVLGAD----------LPSSMKEKAKAE 128
+S+ ++E+ E E K +++ + D + SS + + K E
Sbjct: 1537 SSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEE 1596
Query: 129 TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTL-----------VSETEEEG 177
T+ GK T K+ ++ R S + S+ EE
Sbjct: 1597 TKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEEL 1656
Query: 178 SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKG 237
V G + + + SS +T + ++ +P + G+G
Sbjct: 1657 VVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEG 1716
Query: 238 ATPAPPGKAGAVASQTKAGKPEEDSESS-SEESSDSEEE-----TPAAKALLQAKASGKT 291
++ S T +EDS+SS S + +S+++ P L + S +
Sbjct: 1717 SSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEE 1776
Query: 292 SQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK 351
++ KE + + + +++ S S + D +E + +
Sbjct: 1777 EELREEEELLKEQEK----------------QREIEQQQRKSSSKKSKKDKDELRAQRRR 1820
Query: 352 PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 411
K P P+ SP + A+P + AA ++ + S S ESD +
Sbjct: 1821 ERPKTP-------PSNLSPIEDASPT--EELRQAAEMEELHRSSCSEYSPSIESDPEGFE 1871
Query: 412 LAAMNAAQVKPLGKSP 427
++ +V+ + K P
Sbjct: 1872 ISPEKIIEVQKVYKLP 1887
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 125 bits (315), Expect = 2e-28
Identities = 297/1442 (20%), Positives = 497/1442 (34%), Gaps = 207/1442 (14%)
Query: 80 DPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSM 139
D IS SE+S+EE T K + G P ++ K ++ G + +
Sbjct: 177 DLISDSEASQEE------TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
Query: 140 PHPATGKTVANLLSGK---SPRKSAEPSANTTLVSETEE-------EGSVPAF------- 182
T K++++ K P + +P T +T+ + S P
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVR 290
Query: 183 GAAAKPGMVSAG----QADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGA 238
G + KP + S Q + + + + ++ Q + P PG
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 239 TPA-PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT------ 291
P PPG A KP S + SS E P KAL Q GKT
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSS----EQPGPKALAQPPGVGKTPAQQPG 406
Query: 292 ------SQVGA----ASAPAKESPRKGAAPA--PPGKTGPAVAKAQ-AGKREEDSQSS-- 336
QVG A P +SP K P P + GP AQ AG + +Q +
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 337 ----SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA-AQVQV 391
S+ + P Q P+ PQ ++ P + P G+ PP++ GPA + Q
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKPSPQQP 524
Query: 392 GKQEEDSRSSSEESDSDREALAAMNAAQ--VKPLGKSPQVKPASTMGMGPLGKGAGPVPP 449
G + S+ S ++ A +AQ KP+ ++ KP + P K PP
Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ----PP 580
Query: 450 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA------------------- 490
+ P T + E E+++ ++ E T V
Sbjct: 581 SQGLPKT-ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLN 639
Query: 491 --QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 548
+++LG L P+S P K PV K + + D+A ++
Sbjct: 640 CQMKRALGGDLAPVPSSPQ---PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSK 696
Query: 549 AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR--VGTQAPRKAGTATSPAGSSPAVA 606
A + P +K P P +A AK P + AP K + S +P
Sbjct: 697 APEPKKPPPLVKQPTLHGSP-----SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751
Query: 607 GGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL 666
++P +++ S T + + +S + + + P+K + +
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE----EKTTPPLKTDSAKPSQSFP 807
Query: 667 PG--KTGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKANPAAA 720
P K P ++ DS+ S E+ P Q K KK Q K +P
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 721 RAPSAKGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA 778
P KG+ + PG TA Q+SP + R N + P S P+
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT------ 921
Query: 779 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT- 837
T + TG G+S S + T Q P H AP K++P PT
Sbjct: 922 TPQETVTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQPPTS 976
Query: 838 --PPGKTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRS 890
PP TG P+ + K++ ++E+ + E V + K P P +
Sbjct: 977 QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKD 1032
Query: 891 PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM--- 947
A P +A + K+ EST +E P + V +
Sbjct: 1033 SKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGF 1092
Query: 948 -PTAH-PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ 1005
PT H I + + S ++ D +K PA K +P +P ++ K
Sbjct: 1093 NPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-PAPSGPKASPMPVPTESSSQKTAVP 1151
Query: 1006 ---KASEAQPPVARTQPSSGVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPEVQQA 1059
K + Q +T+ + V ++ P T+ Q + +KL K K +Q+
Sbjct: 1152 PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211
Query: 1060 TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE--TAAESSED 1117
PE + EE+ + K PTP + L E +A E +
Sbjct: 1212 KPLPE---------EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKH 1262
Query: 1118 DVVAPSQSLLSGYMTPGLTPANSQASKATP-KLDSSPSVS----------STLAAKDDPD 1166
D++ + + + P Q K K++ PS + +T K+ P
Sbjct: 1263 DLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQ 1322
Query: 1167 GKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQ 1226
AKP Q KT ++ S T+ + K +G + S+ + S++ + +
Sbjct: 1323 PPCTAKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPS 1379
Query: 1227 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAA 1280
P +E + + K D+ + S S KL + A+
Sbjct: 1380 LIPTDEKDILKGLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQAS 1425
Query: 1281 RTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDE 1340
K +KK E VSPE+ K ++ + + E++ K S ++E
Sbjct: 1426 TLADEKSEKKTQPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEE 1474
Query: 1341 PEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKK 1400
++ +K Q P SK K+KS+ ++E +++S ++ Q+K
Sbjct: 1475 RKDTFKKD------SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK 1528
Query: 1401 KK 1402
++
Sbjct: 1529 RR 1530
Score = 100 bits (250), Expect = 8e-21
Identities = 309/1435 (21%), Positives = 490/1435 (34%), Gaps = 294/1435 (20%)
Query: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGT 233
E EG AAA G ++G A S S + E D+ + E+ Q+ A + A+G
Sbjct: 8 EGEGLPEGLAAAAAAGGGASG-AGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGL 66
Query: 234 PGKGATPA-----------------PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE- 275
P PA PP ++G + +P S+S + ++ SE++
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGL-SKSRTTDTFRSEQKL 125
Query: 276 ---TPAAKALLQAKA-------------SGKTSQVGAASAPA------------------ 301
+P+ +L ++K+ G S+V A SA +
Sbjct: 126 PGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEAS 185
Query: 302 ------------KESPRKGAAPAPPGKTGP--AVAKAQAGKREEDSQSSSEESDSEE--- 344
KE + PP + P + K Q R+ Q + +S S +
Sbjct: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245
Query: 345 ----EAPAQAKP-----------SGKAPQVRAASAPAKESP----RKGAAPAPPRKTGPA 385
+ P KP K P R AS P + + P+ P + P
Sbjct: 246 KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 386 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP-QVKPASTMGMGPLGKGA 444
Q GK + E+S A + KPL + P VKP + P G
Sbjct: 306 IQQPTPGKPPA-QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP----VQPPGTTK 360
Query: 445 GPVPPGKVGPATPSA-QVGKWEEDSESSSEESSDSSDGEVPT-------AVAPAQEKSLG 496
P P +GPA P A Q G + SE ++ G T A P Q+
Sbjct: 361 PPAQP--LGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418
Query: 497 NILQAKP-------TSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
L +P P K P Q+ GP + + P S + PA
Sbjct: 419 KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAK 478
Query: 550 MTAAQAKPALKIPQTKACPK-KTNTTASAKVAPVRVG--TQAPRKAGTATSPAGSSPAVA 606
Q PA PQ K + S K P + G +P++ G+ P+ +
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 607 GGTQRPAEDSSSSEESDSEEEKTGL-------AVTVGQAKSVGKGLQVKAA--------- 650
Q+P+ S+++S +TG V+ + +GL
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL 598
Query: 651 -SVPVKGSLG-----QGTAPVLPG-KTGPTVTQVK---------------------AEKQ 682
VP K + Q T L G P +T+VK + Q
Sbjct: 599 LHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658
Query: 683 EDSESSEEESDSEEAAASPAQVKTSVKKTQA-----------KANPAAARAPSAKGTISA 731
+++ + S + +SP +TS KK A K P + P+ G+ SA
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 732 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKA---VATAAQAQTGPE 788
K A + +P K +P V + Q+ +A P + K + +++ A T P
Sbjct: 719 KAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP- 776
Query: 789 EDSGSSEEESDSEEEAE---TLAQVKPSGKTHQIRAALAP--AKESPRKGAAPTPPGKTG 843
D SS+ +S +EE+ KPS ++P +K PR + G
Sbjct: 777 -DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835
Query: 844 PSAAQAG-KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ 902
PS+ G KQ D EE +A ++ KP P SP P P Q
Sbjct: 836 PSSESKGQKQVDPVQKKEEPK---KAQTKMSPKPDAKPM-----PKGSPTPPGPRPTAGQ 887
Query: 903 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 962
TP+++ + +R S P +Q TP + K G
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP------------QETVTGKLFGFG 935
Query: 963 ASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSG 1022
AS ++S + Q GP +Q P + Q + +QPP ++ P S
Sbjct: 936 ASIFSQASNLISTAGQPGPHSQSGPGAP------------MKQAPAPSQPPTSQGPPKS- 982
Query: 1023 VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA--TKAPESSDDSEDSSDSSSGSE 1080
G P +S V+ + + P+ +QA K E+ DS S +
Sbjct: 983 ----TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTA 1038
Query: 1081 EDGEGPQGAKSAHTL-VGPTPSRTETLVEETAAESSED--------DVVAPSQSLLSGYM 1131
E PQ A L P P T L + S+D + +L
Sbjct: 1039 E----PQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094
Query: 1132 TPGLTP------ANSQASKATP-------KLDSSPS--VSSTLAAKDDPDGKQEAKPQQA 1176
TP LT N Q +A K+ +PS +S + + ++ A P Q
Sbjct: 1095 TPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQV 1154
Query: 1177 AGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQ 1236
+ + K A +K ++ TL+++ Q E++++
Sbjct: 1155 KLVKKQEQEVKTEAEKVILEKVKE-----------TLSMEKIPPMVTTDQ--KQEESKLE 1201
Query: 1237 ASVVKVLTEL--LEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAG 1294
L E L +E+K + + K S E +K L +P TP KK
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRS----EEKKPLLEEKKP---TPEDKK------- 1247
Query: 1295 EGGEASVSPE-KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVE 1353
+ PE KTS + K K+ + E+K +G + + + E ++ K G
Sbjct: 1248 ------LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQPQTKMEGLPS 1300
Query: 1354 GGDQSNPKSKKEKKKSDKRK-------KDKEKKEKKKKAKKASTKDSESPSQKKK 1401
G QS PK + K+ K + K + + K+K +K K S SQ+ K
Sbjct: 1301 GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355
Score = 93.6 bits (231), Expect = 1e-18
Identities = 212/999 (21%), Positives = 338/999 (33%), Gaps = 181/999 (18%)
Query: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD-- 341
+A G+ G A+A A GA P+ AG + SQ S EE
Sbjct: 4 EASLEGEGLPEGLAAAAAAGGGASGAG-------SPSHTAIPAGMEADLSQLSEEERRQI 56
Query: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 401
+ + AQ P G P AA +P+ ++ + PP+++G G+ + S
Sbjct: 57 AAVMSRAQGLPKGSVPPA-AAESPSMHRKQELDSSHPPKQSGRPP---DPGRPAQPGLSK 112
Query: 402 SEESDSDREALAAMNAAQVKPLGKSPQV----KPASTMGMGPLGKGAGPVPPGKVGPATP 457
S +D+ R ++ K G+SP + S + K + + PG +
Sbjct: 113 SRTTDTFR--------SEQKLPGRSPSTISLKESKSRTDLKEEHKSS--MMPGFLSEVNA 162
Query: 458 ----SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 513
S+ V K+ S E+S + V Q K G I++ P K P+
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG-IIKPPLQQQPPKPIPK 221
Query: 514 KAGPVAVQVKAEKPMDNSESSEE-SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 572
+ GP P+ + + SS + ++ T + + PQT
Sbjct: 222 QQGP------GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ 275
Query: 573 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 632
AS QA G + P+ SP+ Q+P +++ E+ + G A
Sbjct: 276 RDASRPQTK-----QADIVRGESVKPSLPSPSKPP-IQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 633 VTVGQAKSVGKGLQVKAASV--PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEE 690
Q + K L + +V PV+ PG T P + K ++ E
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQP----------PGTTKPPAQPLGPAKPPAQQTGSE 379
Query: 691 ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 750
+ SE+ V KT A+ P A+ P+ + P A Q +SP+K
Sbjct: 380 KPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQQVGTPKP-----LAQQPGLQSPAKA 433
Query: 751 KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS--------SEEESDSEE 802
P + P V GP +P+ + QTGP + ++ ++
Sbjct: 434 PGPTKTP----VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
Query: 803 EAETLAQVKPS----GKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSS 858
+ KP G T PAK SP++ + PP + SA + +Q S
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP---SP 546
Query: 859 SEESDSDGEAPAAVT-SAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTA 917
++ S P + T S + ++PP + + P+ +T E
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
Query: 918 RSSSSESEDEDVIPATQCLTPGIRTN--------------------------VVTMPTAH 951
++ +E + T C G N V + P
Sbjct: 607 FNTCTECQ------TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
Query: 952 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSK----KNPASLPLTQAALKVLAQKA 1007
+ AP + + S S + + KK P +SK K P PL + + A
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP--PLVKQPTLHGSPSA 718
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
QPP A DS P P S Q K KPK P++ + T SS
Sbjct: 719 KAKQPPEA--------DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLL 1127
+ D S S+ ++ EE + D PSQS
Sbjct: 771 SATTKPDIPS-----------------------SKVQSQAEEKTTPPLKTDSAKPSQSF- 806
Query: 1128 SGYMTPGLTPANSQASKATPKLDSS--------PSVSSTLAAKDDPDGKQEAKPQQAAGM 1179
P + SKA P+ S PS S + DP K+E +P++A
Sbjct: 807 ----PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE-EPKKAQTK 861
Query: 1180 LSPKTGGKEAASGT---------------TPQKSRKPKK 1203
+SPK K G+ TPQ+S KP++
Sbjct: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Score = 88.2 bits (217), Expect = 5e-17
Identities = 254/1255 (20%), Positives = 435/1255 (34%), Gaps = 275/1255 (21%)
Query: 62 KRKAEEDAALQAKKTRVSDPISTSESSE----EEEEAEAETAKATPRLASTNSSVLGADL 117
K K +A +K +P SE + +++ + + K T L S++S+ D+
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 118 PSS-MKEKAKAETEKAGKTGNSMPH---PATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
PSS ++ +A+ +T KT ++ P P TG+ V+ S PR P++++ ++S
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR----PASDSKIISH- 833
Query: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGT 233
PG S + + + + K S K A KG+
Sbjct: 834 --------------PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK----PDAKPMPKGS 875
Query: 234 PGKGATPAPPGKAG-AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292
P P P AG V + ++ KP+E S S + + Q +GK
Sbjct: 876 P---TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932
Query: 293 QVGAAS-APAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK 351
GA+ + A P P ++GP QA + S K
Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP-----------K 981
Query: 352 PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 411
+G+AP A S P K+ + AA K P A Q K+ E + DS
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAA----EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037
Query: 412 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-------------PS 458
A L KSP KP ST + G P T P+
Sbjct: 1038 AEPQKAVLPTKLEKSP--KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPT 1095
Query: 459 AQVGKWEE--DSESSSEESSDSSDGEV-PTAVAPAQEKSLGNILQAKPTSSPAKGPPQ-- 513
+ + +E ++ + G++ AP+ K+ + + +S PPQ
Sbjct: 1096 PHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155
Query: 514 --KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP--K 569
K V+ +AEK + E+ ++ E+ P +T Q + K+ + KA +
Sbjct: 1156 LVKKQEQEVKTEAEKVI-----LEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQE 1210
Query: 570 KTNTTASAKVAP----VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAE---DSSSSEES 622
K K+ P +R + P +P T P E D S+
Sbjct: 1211 KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQ 1270
Query: 623 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQ 682
+EE+ G + GK Q K +P GT LP + T +K + Q
Sbjct: 1271 IAEEKLEGRVAP--KTVQEGKQPQTKMEGLP------SGTPQSLPKEDDKTTKTIKEQPQ 1322
Query: 683 EDSESSEEESDSEEAAASPAQVKTSVKKTQA---KANPAAARAPSAKGTISAPGKVVTAA 739
A P QV+ +KT+ K++ ++++ P + +S G
Sbjct: 1323 PP------------CTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGI 1370
Query: 740 AQAKQRSPSKVKPPVRN---------------PQNSTVLARGPASVPSVGKAVATA---- 780
+ + PS + ++ P + + LA+ ++V S+ +A A+
Sbjct: 1371 SSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430
Query: 781 -AQAQTGPEEDSG--------------------SSEEESDSEEEAETL-----AQVKPSG 814
++ +T P E S S EE +S+EE + Q PS
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490
Query: 815 KTHQIRAALAP-----------AKESPRKGAAPTPPGK----TGPSAAQAGKQDDSGSSS 859
K H+ ++ +ES +P P K G S++ KQ+DS S
Sbjct: 1491 KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSG 1550
Query: 860 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 919
EE D I+ +I + + +G S + ++ S
Sbjct: 1551 EEED-------------FIRKQIIEMSADEDASG-----------SEDDEFIRNQLKEIS 1586
Query: 920 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 979
SS+ES+ ++ +T G H R+ K+S S +++ R ++
Sbjct: 1587 SSTESQKKEETKGKGKITAG----------KHRRLTRKSS---TSIDEDAGRRHSWHDED 1633
Query: 980 GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTS 1039
A S + LK K+ E++ V G T+ S +
Sbjct: 1634 DEAFDESPE-----------LKYRETKSQESEELVV---TGGGGLRRFKTIELNSTIADK 1679
Query: 1040 VQAKGTNKL------RKPKLPEVQQATKAPE----------------------SSDDSED 1071
A+ + K +P+L E++ T +PE +S S D
Sbjct: 1680 YSAESSQKKTSLYFDEEPEL-EMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLD 1738
Query: 1072 SSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYM 1131
SS S + GE Q K+ H GP + T +SSE++ + + LL
Sbjct: 1739 EDSDSSPSHKKGESKQQRKARHRPHGP--------LLPTIEDSSEEEELREEEELL---- 1786
Query: 1132 TPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPD----GKQEAKPQQAAGMLSP 1182
+ + +++ SS+ +K D D ++ +P+ LSP
Sbjct: 1787 ---------KEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSP 1832
Score = 49.3 bits (116), Expect = 3e-05
Identities = 153/791 (19%), Positives = 270/791 (34%), Gaps = 124/791 (15%)
Query: 197 DSSSEDTSS-------SSDETDVEVKASEKILQ-----VRAASAPAKGTPGKGATPAPPG 244
+SSS+ T+ E +V+ +A + IL+ + P T + +
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201
Query: 245 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES 304
K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEK------------------ 1239
Query: 305 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP----SGKAPQVR 360
P P K AK A + ++ S+ +EE+ + P GK PQ +
Sbjct: 1240 -----KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTK 1294
Query: 361 AASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDR 409
P+ K + P PP P QV+ GK++ + ++ S +
Sbjct: 1295 MEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQ 1352
Query: 410 EALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSE 469
+ KSPQ + + G +P + P + ++D
Sbjct: 1353 QP-------------KSPQGLSDTGYSSDGISSSLGEIP--SLIPTDEKDILKGLKKD-- 1395
Query: 470 SSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMD 529
S S+ESS SS ++ E ++ +IL+A+ ++ + +K P V + K +
Sbjct: 1396 SFSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQE 1450
Query: 530 NSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 589
++S E+ + SEE + + K K + P + ++ + P
Sbjct: 1451 KTQSLSETLEITISEE-EIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREP 1509
Query: 590 RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDSEEEKTGLAVTVGQAKSV 641
+ +S + +SP V +R + SSSS+E S EE+ + A
Sbjct: 1510 YDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADED 1568
Query: 642 GKG-----------LQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDS--ESS 688
G ++ +++ K +G + GK + ED+ S
Sbjct: 1569 ASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHS 1628
Query: 689 EEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAKGTISAPGKVVTAAAQAK 743
+ D E SP K +++ R + + + K ++Q K
Sbjct: 1629 WHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKK 1688
Query: 744 -----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 798
P + + G +S+ + T+ + + +EDS SS
Sbjct: 1689 TSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHK 1748
Query: 799 DSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPPGKTGPSAAQAGKQDDSG 856
E + + A+ +P G L P E S + + +Q
Sbjct: 1749 KGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRK 1801
Query: 857 SSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASEST 916
SSS++S D + A + K P N SP A+ + + A+ + S +
Sbjct: 1802 SSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTEELRQAAEMEELHRSSCS 1857
Query: 917 ARSSSSESEDE 927
S S ES+ E
Sbjct: 1858 EYSPSIESDPE 1868
Score = 49.3 bits (116), Expect = 3e-05
Identities = 86/422 (20%), Positives = 160/422 (37%), Gaps = 60/422 (14%)
Query: 61 RKRKAEEDAALQAKKTRVSDP----ISTSESSEEEEEAEAETAKATPRLASTNSSVLGAD 116
+K E+ L KT + + S+ EE+ E A T + + +
Sbjct: 1239 KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEG- 1297
Query: 117 LPSSMKEKAKAETEKAGKTGNSMPHP---------ATGKTVANLLSGKSPRKSAEPSANT 167
LPS + E +K KT P P GK KS S++ +
Sbjct: 1298 LPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Query: 168 TLVSET--------EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASE- 218
+S+T G +P+ + ++ + DS S+++S SS +++++
Sbjct: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL 1417
Query: 219 KILQVRAAS----APAKGTPGKGATPAPP---GKAGAVASQTKAGKPEEDSESSSEE--- 268
IL+ +A++ K T +P P K +++ + EE+ + S EE
Sbjct: 1418 SILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKD 1477
Query: 269 --SSDSEEETPAAKALLQAKASGKTSQVGAASAP---AKESPRKGAAPAPPGKTGPAVAK 323
DS+++ P++K + S + P +ES +P P K +V
Sbjct: 1478 TFKKDSQQDIPSSKD--HKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGS 1535
Query: 324 AQAGK-REEDSQSSSEESD----------SEEEAPAQAKPSGKAPQVRAASAPAKESPRK 372
+ + + ++EDSQ S EE D ++E+A Q++ S+ + ES +K
Sbjct: 1536 SSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISS-STESQKK 1594
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
+ ++ GK +R SS D D + + + +SP++K
Sbjct: 1595 --------EETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYR 1646
Query: 433 ST 434
T
Sbjct: 1647 ET 1648
Score = 35.0 bits (79), Expect = 0.51
Identities = 91/409 (22%), Positives = 149/409 (36%), Gaps = 47/409 (11%)
Query: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGT---PGKGATPAP 242
A PG++S T S TDV VK EK + R++ A +G G+ T P
Sbjct: 3386 APPGILS----------TVSEIPLTDVVVK-EEKQPKKRSSGAKVRGQYDDMGENMTDDP 3434
Query: 243 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS-QVGAASAPA 301
V S + D E +++ S S + K S TS Q
Sbjct: 3435 RSFKKIVDSGVQT-----DDEDATDRSYVSRRR--------RTKKSVDTSVQTDDEDQDE 3481
Query: 302 KESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG--KAPQV 359
+ P + A GK G ++ +A K + S+ SS + E Q +P G + P +
Sbjct: 3482 WDMPTRSRRKARVGKYGDSM--TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSI 3539
Query: 360 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 419
RA E + +AP K G Q E DS + S + S
Sbjct: 3540 RARVDAKVEIIKHISAPEKTYKGGSLGCQT-----EADSDTQSPQYLSATSPPKDKKRPT 3594
Query: 420 VKPLGKSPQVKPASTMGMGPLGKGA-----GPVPPGKVGPATPSAQVGKWEEDSESSSEE 474
+G S ++ ST+ + P + P+ P G A SA V + + S +
Sbjct: 3595 PLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQ 3654
Query: 475 SSDSSD-GEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 530
D +VP A A ++S+ + PT+ + P + K + M +
Sbjct: 3655 KVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQY-TEGYTTKGSQTMTS 3713
Query: 531 SESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV 579
S + ++ + + T Q+ + ++ +TNT A AK+
Sbjct: 3714 SGAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKI 3762
Score = 30.8 bits (68), Expect = 9.6
Identities = 76/436 (17%), Positives = 155/436 (35%), Gaps = 67/436 (15%)
Query: 24 VRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPIS 83
+ ++++ KE+S F+ T + Y +++SE E++ + +K R S S
Sbjct: 1487 IPSSKDHKEKSE---FVDDITTRREPYDSVEESSE-------SENSPVPQRKRRTSVGSS 1536
Query: 84 TSESSEEEE-----EAEAETAKATPRLASTNSSVLGAD----------LPSSMKEKAKAE 128
+S+ ++E+ E E K +++ + D + SS + + K E
Sbjct: 1537 SSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEE 1596
Query: 129 TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTL-----------VSETEEEG 177
T+ GK T K+ ++ R S + S+ EE
Sbjct: 1597 TKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEEL 1656
Query: 178 SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKG 237
V G + + + SS +T + ++ +P + G+G
Sbjct: 1657 VVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEG 1716
Query: 238 ATPAPPGKAGAVASQTKAGKPEEDSESS-SEESSDSEEE-----TPAAKALLQAKASGKT 291
++ S T +EDS+SS S + +S+++ P L + S +
Sbjct: 1717 SSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEE 1776
Query: 292 SQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK 351
++ KE + + + +++ S S + D +E + +
Sbjct: 1777 EELREEEELLKEQEK----------------QREIEQQQRKSSSKKSKKDKDELRAQRRR 1820
Query: 352 PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 411
K P P+ SP + A+P + AA ++ + S S ESD +
Sbjct: 1821 ERPKTP-------PSNLSPIEDASPT--EELRQAAEMEELHRSSCSEYSPSIESDPEGFE 1871
Query: 412 LAAMNAAQVKPLGKSP 427
++ +V+ + K P
Sbjct: 1872 ISPEKIIEVQKVYKLP 1887
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 118 bits (296), Expect = 4e-26
Identities = 263/1233 (21%), Positives = 428/1233 (34%), Gaps = 191/1233 (15%)
Query: 65 AEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLG--ADLPSSMK 122
+ E L A S P++TS E + TA+ T ST S P S
Sbjct: 938 SSEARTLSATPVDTSTPVTTST----EATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHT 993
Query: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAF 182
A +E T P T T A+ SP +AE T++ + T EGS P
Sbjct: 994 LVANSEASTLSTTPVDSNTPLTTSTEAS-----SPPPTAE---GTSMPTSTPSEGSTPLT 1045
Query: 183 GAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP 242
MV++ + + S + +S +AS S P T +G+TP
Sbjct: 1046 RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTS-TYSEGSTP-- 1102
Query: 243 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK 302
+ S + + SE+S+ ++ + P + +AS + S P
Sbjct: 1103 ------LTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTS---TEASSSPTTAEGTSIPTS 1153
Query: 303 ESPRKGAAP--APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
P +G P + P T V+ E + S+ DS+ + + S P
Sbjct: 1154 P-PSEGTTPLASMPVSTTLVVSS-------EANTLSTTPVDSKTQVATSTEASSPPPTAE 1205
Query: 361 AASAPAKESPRKGAAPA---PPRKTGPAAAQVQVGKQEEDSRS-----SSEESDSDREAL 412
S P +P + + P P R T A+++ S S+E S S A
Sbjct: 1206 VTSMPTS-TPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAE 1264
Query: 413 AAMNAAQVKPLGKS--PQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSES 470
G + + ++T+ P P GP S +V +E
Sbjct: 1265 GTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEG 1324
Query: 471 SSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 530
+S +S S+G P P + + A+ + + P+DN
Sbjct: 1325 TSMPTSTYSEGRTPLTSIPVNTTLVASS--------------------AISILSTTPVDN 1364
Query: 531 SESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR 590
S S+++ S + + P+ + P T S++ + +
Sbjct: 1365 STPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTS 1424
Query: 591 KAGTATSPAGSSPAVAGG----TQRPAEDSS-------SSEESDSEEEKTGLAVTVGQAK 639
GT ++ A SSP A G T P+E + S+ + E T V
Sbjct: 1425 TPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNS 1484
Query: 640 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 699
V V ++ P +G+ A P + +T + S ++ S+ +
Sbjct: 1485 PVVTSTAVSSSPTPAEGT---SIAISTPSEGSTALTSIPV-----STTTVASSEINSLST 1536
Query: 700 SPAQVKTSVKK-TQAKANPAAARAPSAKGTISAPGK------------VVTAAAQAKQRS 746
+PA T V +QA ++P A S + + + G VV++ A +
Sbjct: 1537 TPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTT 1596
Query: 747 P--SKVKPPVRNPQNSTVLARGPA---SVPSVGKAVATAAQAQTGP---EEDSGSSEEES 798
P SK + +S+ A G + S PS G + T+ T P E S S
Sbjct: 1597 PIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPV 1656
Query: 799 DSEEEAETLAQVKPS----------------GKT--HQIRAALAPAKESPRKGAAPTP-- 838
DS T +V S G+T I P S + TP
Sbjct: 1657 DSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVD 1716
Query: 839 ---PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 895
P T A + + S + S+G P +TS V P++ + + A P
Sbjct: 1717 NSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTP--LTSIPVSTTPVLSSEASTLSATPI 1774
Query: 896 ATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 955
T STP + ST +SS + + IP T L+ G+ T + + P +H +A
Sbjct: 1775 DT-------STP----VTTSTEATSSPTTAEGTSIP-TSTLSEGM-TPLTSTPVSHTLVA 1821
Query: 956 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1015
+ E+S +S T V +P ++ A+ S +A
Sbjct: 1822 ----------NSEASTLS--------TTPVDSNSPVVTSTAVSSSPTPAEGTS-----IA 1858
Query: 1016 RTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL-RKPKLPEVQQATKAP-ESSDDSEDSS 1073
+ PS G +A+ ++P + +T+V + TN L P + T A SS + D S
Sbjct: 1859 TSTPSEG-STALTSIPVS---TTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGS 1914
Query: 1074 DSSSGSEEDGEGP---------QGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQ 1124
+ + +G P A S + T + T T V T +++S A
Sbjct: 1915 SMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPV-TTYSQASSSPTTADGT 1973
Query: 1125 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1184
S+ + + G TP S T + S S ST P G SP T
Sbjct: 1974 SMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLST-----TPVDTSTPATTSTEGSSSPTT 2028
Query: 1185 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1217
G + +TP + P AG P ++TL + S
Sbjct: 2029 AGGTSIQTSTPSERTTPL--AGMPVSTTLVVSS 2059
Score = 106 bits (265), Expect = 1e-22
Identities = 240/1209 (19%), Positives = 417/1209 (34%), Gaps = 132/1209 (10%)
Query: 76 TRVSDPI-STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK 134
T S P+ ST S+ +E T TP T++ V + PSS+ A+A T
Sbjct: 330 TEGSTPLTSTPASTMPVATSEMSTLSITP--VDTSTLVTTSTEPSSLPTTAEA-TSMLTS 386
Query: 135 TGNSMPHPATGKTVANLL--SGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
T + P T V+ +L S ++ S P + T V+ E S P
Sbjct: 387 TLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSP------------ 434
Query: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
+++EDTS + T + S + + ++ P + + P V +
Sbjct: 435 -----TTAEDTSIA---TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTS 486
Query: 253 TKAGKPEEDSE-SSSEESSDSEEETP------AAKALLQAKASG-KTSQVGAASAPAKES 304
T+A +E +S S+ SE TP + + ++AS T+ V ++ S
Sbjct: 487 TEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSS 546
Query: 305 PRKGAAPAPPGKTGPAVAKAQAGK-------------REEDSQSSSEESDSEEEAPAQAK 351
++ P G + P ++ E S +S+ +DS ++
Sbjct: 547 EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSE 606
Query: 352 PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 411
S + S P +G + A + S+ + EA
Sbjct: 607 ASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEA 666
Query: 412 LAAMNAAQVKPLGKSPQVKPASTMGMGPL---------GKGAGPVPPGKVGPATPSAQVG 462
++ A+ + S + ++ + P+ P P T S +
Sbjct: 667 TSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS 726
Query: 463 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 522
++ +S +S S+G P P + +L + S+ + P + +
Sbjct: 727 SSPTTADGASMPTSTPSEGSTPLTSMPVSK----TLLTSSEASTLSTTPLDTSTHITTST 782
Query: 523 KAEKPMDNSESSEESSDSADSEEAP---------AAMTAAQAKPALKIPQTKACPKKTNT 573
+A +E + S SE +P +T+ +A P P T+T
Sbjct: 783 EASCSPTTTEGT-SMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTST 841
Query: 574 TASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAV 633
S+ P GT P T+T G +P + +S+ + T V
Sbjct: 842 EVSSSPTPAE-GTSMP----TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPV 896
Query: 634 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV--LPGKTGPTV-TQVKAEKQEDSESSEE 690
T ++ + S+P + G+G+ P+ +P T P V ++ + ++S
Sbjct: 897 T-NSTEARSSPTTSEGTSMPT-STPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTP 954
Query: 691 ESDSEEAAASPAQVK-TSVKKTQAKANPAAARAPSAKGTISAPGKVVT-AAAQAKQRSPS 748
+ S EA +SP + TS+ + + T+ A + T + +P
Sbjct: 955 VTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPL 1014
Query: 749 KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQT---GPEEDSGSSEEESDSEEEAE 805
+P + P S PS G T T E S S +D+
Sbjct: 1015 TTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVT 1074
Query: 806 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESD-- 863
T +Q S T A + + TP S + S S+ D
Sbjct: 1075 TYSQASSSSTT-----ADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTS 1129
Query: 864 ----SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 919
+ EA ++ T+A+ P SP TP + ST +SE+ S
Sbjct: 1130 IPVTTSTEASSSPTTAEGTSIP-------TSPPSEGTTPLASMPVSTTLVV-SSEANTLS 1181
Query: 920 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP--RIAPKASMAGASSSKESSRISDGKK 977
++ V +T+ +P V +MPT+ P R P SM + SS S
Sbjct: 1182 TTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEAS---- 1237
Query: 978 QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQP-PVARTQPSSGVDSA--VGTLPATS 1034
T + S P+T +A + +E P + T S + ++ V T TS
Sbjct: 1238 -----TLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTS 1292
Query: 1035 PQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG----AK 1090
P+++++ + + P + + ++ + S +S S G P A
Sbjct: 1293 PEASTLLTTPVD-TKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVAS 1351
Query: 1091 SAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLD 1150
SA +++ TP T V T+ E+ + S+ + + G TP S TP +
Sbjct: 1352 SAISILSTTPVDNSTPV-TTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVS 1410
Query: 1151 SSPSVSSTLAAKDDPDGKQEAK----PQQAAGMLSPKTGGKEAASGTTPQKS-RKPKKGA 1205
S S S G A+ P A G+ P + E G TP KS
Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSE---GKTPLKSIPVSNTPV 1467
Query: 1206 GNPQASTLA 1214
N +ASTL+
Sbjct: 1468 ANSEASTLS 1476
Score = 102 bits (254), Expect = 3e-21
Identities = 215/1139 (18%), Positives = 377/1139 (33%), Gaps = 141/1139 (12%)
Query: 70 ALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAET 129
A + T I+TS SE + TP +S S++ + S + E
Sbjct: 430 ASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEA 489
Query: 130 EKAGKTG--NSMPH--PATGKTVANLLSGKS-PRKSAEPSA------------------- 165
+ T NSMP P+ G T +S + P S+E S
Sbjct: 490 SSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEAS 549
Query: 166 -------NTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASE 218
T++ + T EGS P +V + +A ++S + S+ +AS
Sbjct: 550 SSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASS 609
Query: 219 KILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA----------GKPEEDSESSSEE 268
S P +G T + + + ++A P S ++
Sbjct: 610 SSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSS 669
Query: 269 SSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK 328
S+ +E + + + V + E+ P +A +
Sbjct: 670 STTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSP 729
Query: 329 REEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQ 388
D S + SE P + P K + E+ P + +
Sbjct: 730 TTADGASMPTSTPSEGSTPLTSMPVSK------TLLTSSEASTLSTTPLDTSTHITTSTE 783
Query: 389 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 448
+ S + S+ L + P+ SP+ AST+ P+ +
Sbjct: 784 ASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPV-TSPE---ASTLSTTPVDSNS---- 835
Query: 449 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 508
P T S +V +E +S +S S+G P P + + +++P
Sbjct: 836 -----PVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTP- 889
Query: 509 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 568
V P+ NS + S +++ P + + P +P + P
Sbjct: 890 -------------VDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDS-TTP 935
Query: 569 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEK 628
++ + PV T T ++ A SSP A GT P S +
Sbjct: 936 VVSSEARTLSATPVDTSTPV-----TTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPV 990
Query: 629 TGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE----KQED 684
+ V +A ++ V + + + P G + PT T + +
Sbjct: 991 SHTLVANSEASTLST-TPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPV 1049
Query: 685 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 744
S + S++ + +PA T V + A++ + +A GT S P + +
Sbjct: 1050 STTMVASSETSTLSTTPADTSTPV----TTYSQASSSSTTADGT-SMPTSTYSEGSTPLT 1104
Query: 745 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 804
P + V + ++ S+P V T+ +A + P G+S S E
Sbjct: 1105 SVPVSTRLVVSSEASTLSTTPVDTSIP-----VTTSTEASSSPTTAEGTSIPTSPPSEGT 1159
Query: 805 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS-SSEESD 863
LA + + L + E+ P ++ +A + +S +
Sbjct: 1160 TPLASM-------PVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTS 1212
Query: 864 SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ-AQAASTPRKARASESTARSSSS 922
+ GE +TS V P+ + + P T +A T +E T+ +S+
Sbjct: 1213 TPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTST 1272
Query: 923 ESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG-ASSSKESSRISDGKKQEGP 981
SE ++ + + T +VT P A + G +S E S S EG
Sbjct: 1273 TSEGSTLLTSIP-----VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVS--SSPTPAEGT 1325
Query: 982 ATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA--TSPQSTS 1039
+ S + PLT PV T +S S + T P ++P +TS
Sbjct: 1326 SMPTSTYSEGRTPLTSI--------------PVNTTLVASSAISILSTTPVDNSTPVTTS 1371
Query: 1040 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPT 1099
+A + P + T P +S+ SE ++ + S P + A TL T
Sbjct: 1372 TEACSS--------PTTSEGTSMP-NSNPSEGTTPLT--SIPVSTTPVVSSEASTL-SAT 1419
Query: 1100 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSST 1158
P T T T+AE++ A S+ + + G TP S TP +S S ST
Sbjct: 1420 PVDTST-PGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLST 1477
Score = 96.3 bits (238), Expect = 2e-19
Identities = 249/1205 (20%), Positives = 419/1205 (34%), Gaps = 169/1205 (14%)
Query: 81 PISTSESSEEEEEAEAETAKATPR---LASTNSSVLGADLPSSMKEKAKAETEKAGKTGN 137
P ST ++S + +TP ++ST + V A LPS +A T K
Sbjct: 130 PSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSF-----EAYTSLTYKVDM 184
Query: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
S P L + S +TT+ T EGS P A V++ +A
Sbjct: 185 STP----------LTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAI 234
Query: 198 SSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATP----------------- 240
+ S + +AS S + P G+TP
Sbjct: 235 TLLTTPVEISTPVTISAQASSSPTTAEGPSL-SNSAPSGGSTPLTRMPLSVMLVVSSEAS 293
Query: 241 ----APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGA 296
P V + T+A +E +S +S E + + + TS++
Sbjct: 294 TLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMST 353
Query: 297 ASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS--------------SEESDS 342
S ++ P P A+A + S+ S S E+ +
Sbjct: 354 LSITPVDTSTLVTTSTEPSSL-PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEAST 412
Query: 343 EEEAPAQAK-------PSGKAPQVRAASAPAKESPRKGAAP--APPRKTGPAAAQVQVGK 393
P +K + +P ++ A +P +G+ P + P T P A+
Sbjct: 413 TSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVAS------ 466
Query: 394 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 453
E S S+ DS + + A+ P + + P ST G
Sbjct: 467 -SEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSM-PTSTPSEG--------------- 509
Query: 454 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 513
+TP + SS + ++ + T V + E S + + TS P P +
Sbjct: 510 -STPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEAS-SSSTTPEGTSIPTSTPSE 567
Query: 514 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT 573
+ P+ + + + +SE+S S+ ADS T+++A + + + P T +
Sbjct: 568 GSTPLTNMPVSTRLVVSSEASTTSTTPADSN--TFVTTSSEASSSSTTAEGTSMPTSTYS 625
Query: 574 TASAKVAPVRVGTQ--APRKAGT-ATSPAGSSPAVAGGTQRPAEDSSSSEESDS------ 624
+ + V T A +A T +T+P S+ V T+ A SS++ E S
Sbjct: 626 ERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTE--ATSSSTTAEGTSMPTSTY 683
Query: 625 EEEKTGL------AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP-VLPGKTGPTVTQV 677
E T L V +++ S PV S ++P G + PT T
Sbjct: 684 TEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPS 743
Query: 678 KAEKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKV 735
+ S S + SE + S + TS T + A+ +P+ S P
Sbjct: 744 EGSTPLTSMPVSKTLLTSSEASTLSTTPLDTS---THITTSTEASCSPTTTEGTSMPIST 800
Query: 736 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE 795
+ + P + PV +P+ ST L+ P S V T+ + + P G+S
Sbjct: 801 PSEGSPLLTSIPVSI-TPVTSPEAST-LSTTPVDSNS---PVTTSTEVSSSPTPAEGTSM 855
Query: 796 EESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS 855
S E L + P T +A++ +P + P T + A++
Sbjct: 856 PTSTYSEGRTPLTSM-PVSTTLVATSAISTLSTTPVDTSTPV----TNSTEARSSPTTSE 910
Query: 856 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 915
G+S S + GE +TS P++ + A P T + +T +A +S +
Sbjct: 911 GTSMPTS-TPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDT---STPVTTSTEATSSPT 966
Query: 916 TARSSS--SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 973
TA +S + + E P T TP T V + P S ++S E+S S
Sbjct: 967 TAEGTSIPTSTPSEGTTPLTS--TPVSHTLVANSEASTLSTTPVDSNTPLTTSTEAS--S 1022
Query: 974 DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASE-----------AQPPVARTQPSSG 1022
EG + S + S PLT+ + +SE + P +Q SS
Sbjct: 1023 PPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSS 1082
Query: 1023 VDSAVGTLPATSPQSTSVQAKGTNKLRK-PKLPEVQQATKAPESSDDSEDSSDSSSGSEE 1081
+A GT TS ++G+ L P + +++A S D+S + S E
Sbjct: 1083 STTADGT-----SMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTE 1137
Query: 1082 DGEGPQGAKSAHTLVGPTPSRTETL----VEETAAESSEDDVVAPSQSLLSGYMTPGLTP 1137
P A+ P T L V T SSE + T TP
Sbjct: 1138 ASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEAN-------------TLSTTP 1184
Query: 1138 ANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAAS-GTTPQ 1196
+S+ AT SSP ++ + + + + P + + EA++ T+P
Sbjct: 1185 VDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPV 1244
Query: 1197 KSRKP 1201
+ P
Sbjct: 1245 DTSTP 1249
Score = 96.3 bits (238), Expect = 2e-19
Identities = 232/1172 (19%), Positives = 404/1172 (34%), Gaps = 119/1172 (10%)
Query: 81 PISTSESSE-EEEEAEAETAKATPRLASTNSSVL-GADLPSSMKEKAKAETEK--AGKTG 136
P+++SE+S A+ T T AS++ + G +P S + T
Sbjct: 2998 PVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTP 3057
Query: 137 NSMPHPATGKTV-----ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
++P +T T + +++ S P+ T++ T EGS P G V
Sbjct: 3058 VAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPV 3117
Query: 192 SAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 251
++ + S +S +A S P TP +G+TP +
Sbjct: 3118 TSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTS-TPSEGSTPLT-----YMPV 3171
Query: 252 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 311
T EDS S+ S T + +A A G S P +P +G P
Sbjct: 3172 STMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG-------TSIPTS-TPSEGMTP 3223
Query: 312 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPR 371
T V+ E S S+ DS + S P S P +P
Sbjct: 3224 L----TSVPVSNTPVASSEA-SILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTS-TPS 3277
Query: 372 KGAAP--APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
+G+ P + P T A+ E S S+ +D+ A+ P+ +
Sbjct: 3278 EGSTPLTSMPVSTTTVASS-------ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM 3330
Query: 430 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
P ST G +TP + SS + ++ + T V
Sbjct: 3331 -PTSTYSEG----------------STPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTT 3373
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
+ E SL A+ TS P P + P+A + P+ +SE + S+ DS
Sbjct: 3374 STEASLSPTT-AEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTT 3432
Query: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
T A + P I + + P T + S ++ + + T A+S A + T
Sbjct: 3433 STEASSSPT--IAEGTSLPTSTTSEGSTPLSIMPLSTTP-----VASSEASTLSTTPVDT 3485
Query: 610 QRPAEDSSSSEESDSEEEKTGLAV-TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG 668
P SS + S + E T + T G+ + + V V + T PV
Sbjct: 3486 STPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSN 3545
Query: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
+ +Q + ++ S E ++S T++ + + A PS
Sbjct: 3546 TFVTSSSQASSSPATLQVTTMRMSTPSEGSSS----LTTMLLSSTYVTSSEASTPSTPSV 3601
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-STVLARGPASVPSVGKAVATAAQAQTGP 787
+ + + + P + P+ P ST L P S SV ++ A A T P
Sbjct: 3602 DRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSV--TISEAGTASTLP 3659
Query: 788 EEDS-----GSSEEESDSEEEAETLAQVKPS-GKTHQIRAALAPAKESPRKGAAPTPPGK 841
+ S + S E T+ PS G T ++ + + +G+ + P
Sbjct: 3660 VDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSV 3719
Query: 842 TGPSAAQAGKQDDSGSSSEESDSDG-----EAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 896
+ + S S++ +S + E T+ V P+ + +P+ P+
Sbjct: 3720 VTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSV 3779
Query: 897 TPAQA-----QAASTPRKARASESTARSSSSESED---EDVIPATQCLTPGIRTNVVTMP 948
+ + + +S+P + + S++SE +I ++P + + T P
Sbjct: 3780 YTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPP 3839
Query: 949 --TAHPRI-APKASMAGASSSKESSRISDGKKQEGPATQ--VSKKNPASLPLTQAALKVL 1003
T+ P + + KA + + RIS ++ P T VS P S P A
Sbjct: 3840 GDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIA---- 3895
Query: 1004 AQKASEAQPPV--ARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATK 1061
+ PP+ + T S ++ T+P + S SV +G+ +P +
Sbjct: 3896 ------STPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSS 3949
Query: 1062 APESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDV-V 1120
+ + + + + + P + S+ T T T TAA + +
Sbjct: 3950 TADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMST 4009
Query: 1121 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
APS TP T S +T S+P S+++ + + ++P
Sbjct: 4010 APS--------TPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHT 4061
Query: 1181 SPKTGGKEAASGTTPQKSRKPKKGAGNPQAST 1212
P T A S T P S NP+A T
Sbjct: 4062 IPPT-FPPAHSSTPPTTS--ASSTTVNPEAVT 4090
Score = 95.9 bits (237), Expect = 2e-19
Identities = 265/1413 (18%), Positives = 456/1413 (32%), Gaps = 243/1413 (17%)
Query: 81 PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMP 140
P++T + T+ TP + ++ + L +++ ++A T S P
Sbjct: 1956 PVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTP 2015
Query: 141 HPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSS 200
AT T + S + T++ + T E + P G +V + + ++ S
Sbjct: 2016 --ATTSTEGS--------SSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLS 2065
Query: 201 EDTSSSSDETDVEVKASEKILQVRAA---SAPAKGTPGKGATPAPPGKAGAVASQTKAGK 257
S + +AS ++ SAP++G+P + P S T
Sbjct: 2066 TTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPL---------STTPVAS 2116
Query: 258 PEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS---APAKESPRKGAAPA-- 312
PE + S++ S+S T + G + Q S P P A
Sbjct: 2117 PEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASS 2176
Query: 313 --------PPGKTGPAVAKAQAGKREEDSQSSS--EESDSEEEAPAQAKPSGKAPQVRA- 361
P + P +A S+ +S + SE P + P P V +
Sbjct: 2177 AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSE 2236
Query: 362 ----------ASAPAKESPRKGAAPAPPRKTGPAAAQVQVG--------------KQEED 397
S P S ++P T + + G E
Sbjct: 2237 ASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEV 2296
Query: 398 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV---------- 447
S S+ DS+ + A+ P + + P ST G PV
Sbjct: 2297 STLSTTPVDSNTPFTTSTEASSPPPTAEGTSM-PTSTSSEGNTPLTRMPVSTTMVASFET 2355
Query: 448 ------PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP------------ 489
P P T +Q G ++ +S +S S+G P P
Sbjct: 2356 STLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAS 2415
Query: 490 --------------AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 535
++ + A+ TS P P + P+A + P+ +SE+
Sbjct: 2416 THSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGT 2475
Query: 536 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT---QAPRKA 592
S+ D+ T A + P + P T + S + + V T +P +
Sbjct: 2476 LSTTPVDTSTPMTTSTEASSSPT--TAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAS 2533
Query: 593 GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASV 652
+T+P S+ V +S+E S S G ++ L+ S
Sbjct: 2534 TLSTTPVDSNSPVV----------TSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVST 2583
Query: 653 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ 712
S T P T VT E S S D+ ++P++V TS+
Sbjct: 2584 KPLASSEASTLSTTPVDTSIPVT----TSTETSSSPTTAKDTSMPISTPSEVSTSLTSIL 2639
Query: 713 AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK---PPVRNP-----------Q 758
P A+ S T + + + SP+ + P P
Sbjct: 2640 VSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILV 2699
Query: 759 NSTVLARGPASVPS-----VGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPS 813
++T+LA AS S V T+A+A + P G+S S + + L + S
Sbjct: 2700 STTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVS 2759
Query: 814 G-----------KTHQIRAALAPAKESPRKGAAPT----------------------PPG 840
T + ++ P S ++PT P
Sbjct: 2760 TLPVASSEASTVSTTAVDTSI-PVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818
Query: 841 KTGPSAAQAGKQDDSG-SSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRS-------PA 892
T ++++AG + +S + +A ++ T+A+ I P+ +
Sbjct: 2819 HTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST 2878
Query: 893 GPAATPAQAQAASTP-----RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 947
P A+ + ++TP ++E ++ +++E + ++ TP V T+
Sbjct: 2879 TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTV 2938
Query: 948 PTAHPRIA-----PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKV 1002
P A + P + ++S E+S S EG + +S PLT ++
Sbjct: 2939 PVAGSEASTLSTTPVDTRTPVTTSAEAS--SSPTTAEGTSMPISTPGERRTPLTSMSVST 2996
Query: 1003 LAQKASEAQ-----------PPVARTQPSSGVDSAVGT-LPATSPQSTSVQAKGTNKLRK 1050
+ +SEA P T+ SS +A GT +P ++P S
Sbjct: 2997 MPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTT 3056
Query: 1051 P-KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT-----LVG-PTPSRT 1103
P +PE + P S+ +S S S EG S ++ L G P +
Sbjct: 3057 PVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTP 3116
Query: 1104 ETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSV---SSTLA 1160
T + ++ D P + + +P + S + +TP S+P ST+
Sbjct: 3117 VTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPT-STPSEGSTPLTYMPVSTML 3175
Query: 1161 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1220
D A P + +P T EA S TT + + P P L S
Sbjct: 3176 VVSSEDSTLSATPVDTS---TPVTTSTEATSSTTAEGTSIP---TSTPSEGMTPLTS--- 3226
Query: 1221 QCLLGQPWPLNEAQVQASVVKVL-TELLEQERKKVVDTTKESSRKGWESRKRKLS----G 1275
P++ V +S +L T ++ T SS E S G
Sbjct: 3227 -------VPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEG 3279
Query: 1276 DQPAARTPRSKKKKKLGAGEGGEASVSPEKTST 1308
P P S + + E S +P TST
Sbjct: 3280 STPLTSMPVS--TTTVASSETSTLSTTPADTST 3310
Score = 95.5 bits (236), Expect = 3e-19
Identities = 263/1218 (21%), Positives = 420/1218 (34%), Gaps = 187/1218 (15%)
Query: 67 EDAALQAKKTRVSDPISTS-ESSEEEEEAEAETAK-ATPRLASTN-SSVLGADLPSSMKE 123
E + L S P++TS E+S AE + + +TP ST +S+L + LP + E
Sbjct: 2708 EASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSE 2767
Query: 124 KAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEE-GSVPAF 182
+ T T P T T A+ SP + S T+ SET S+P
Sbjct: 2768 ASTVST-----TAVDTSIPVTTSTEAS----SSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818
Query: 183 G---AAAKPGMVSAGQADSSSEDTSS---SSDETDVE---------VKASEKILQVRAAS 227
A+++ G +S D+S+ T+S SS T E + S + + ++
Sbjct: 2819 HTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST 2878
Query: 228 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE-SSDSEEETPAAKALLQ-- 284
P + + P + V + T+ +E +S S+ SE TP L+
Sbjct: 2879 TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTV 2938
Query: 285 --AKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEES-- 340
A + T + A+ +P G ++ + G+R S S +
Sbjct: 2939 PVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMP 2998
Query: 341 -DSEEEAPAQAKPSGKAPQV----RAASAPAK--------ESPRKGAAPAP--PRKTGPA 385
S E + P+ + V A+S+P +P +G+ P P T P
Sbjct: 2999 VASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPV 3058
Query: 386 AAQVQ--VGKQEEDSRS----SSEESDSDREALAAMNAAQVKPLGKSPQVK-PASTMGMG 438
A + DS S S+E S S A G +P P ST
Sbjct: 3059 AIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTT--- 3115
Query: 439 PLGKGA----GPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE-- 492
P+ A P P T S + SE +S +S S+G P P
Sbjct: 3116 PVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTML 3175
Query: 493 --KSLGNILQAKP---------------------TSSPAKGPPQKAGPVAVQVKAEKPMD 529
S + L A P TS P P + P+ + P+
Sbjct: 3176 VVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVA 3235
Query: 530 NSESSEESSDSADSEEAPAAMTAAQAKPAL--------KIPQTKACPKKTNTTASAKVAP 581
+SE+S S+ DS T A + P P + P + ++ VA
Sbjct: 3236 SSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVAS 3295
Query: 582 VRVGTQAPRKAGTAT-----SPAGSSPAVAGGTQRPAEDSS-----------------SS 619
T + A T+T S A SSP +A GT P S SS
Sbjct: 3296 SETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSS 3355
Query: 620 EES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV--LPGKTGPTV- 674
E S + T VT S+ + S+P S +GT P+ +P T P V
Sbjct: 3356 EASTLSTTPVDTSTPVTTSTEASLSP-TTAEGTSIPT-SSPSEGTTPLASMPVSTTPVVS 3413
Query: 675 TQVKAEKQEDSESSEEESDSEEAAASP--AQVKTSVKKTQAKANPAAARAPSAKGTISAP 732
++V +S+ + S EA++SP A+ + T ++ + + P + +++
Sbjct: 3414 SEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASS 3473
Query: 733 GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP---EE 789
+ +P P + + + P S G T T P E
Sbjct: 3474 EASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSE 3533
Query: 790 DSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA 849
S S DS + +Q S T Q+ +P +G++ S+
Sbjct: 3534 ASTLSTTPVDSNTFVTSSSQASSSPATLQVTTM---RMSTPSEGSSSLTTMLL--SSTYV 3588
Query: 850 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
+ S S+ D + S PP + P +P+ +TP ST
Sbjct: 3589 TSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPS-EVSTPLTIMPVST-TS 3646
Query: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP--TAHPRIAPKASMAGASSSK 967
SE+ S+ VI +TQ + + TMP T P +M +++
Sbjct: 3647 VTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRV 3706
Query: 968 ESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAV 1027
S S+G P+ S P+T + +A + + T S + +
Sbjct: 3707 TS---SEGSTLSTPSV------VTSTPVTTST------EAISSSATLDSTTMSVSMPMEI 3751
Query: 1028 GTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDS---SDSSSGSEEDGE 1084
TL T ST+ T+ PESS S S S S + + E
Sbjct: 3752 STLGTTILVSTT------------------PVTRFPESSTPSIPSVYTSMSMTTASEGSS 3793
Query: 1085 GPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1144
P + T+ T S TL+ T S V++PS++ S TP
Sbjct: 3794 SPTTLEGTTTMPMSTTSERSTLL--TTVLISPISVMSPSEA--STLSTP-------PGDT 3842
Query: 1145 ATPKLDSSPSVSSTLAAK 1162
+TP L S+ + S ++ A+
Sbjct: 3843 STPLLTSTKAGSFSIPAE 3860
Score = 90.1 bits (222), Expect = 1e-17
Identities = 241/1140 (21%), Positives = 400/1140 (35%), Gaps = 219/1140 (19%)
Query: 65 AEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLG--ADLPSSMK 122
+ ED+ L A S P++TS E + TA+ T ST S + +P S
Sbjct: 3178 SSEDSTLSATPVDTSTPVTTS-----TEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT 3232
Query: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSA-NTTLVSETEEEGSVPA 181
A +E T P T T A+ S+ P+A T++ + T EGS P
Sbjct: 3233 PVASSEASILSTTPVDSNTPLTTSTEAS---------SSPPTAEGTSMPTSTPSEGSTPL 3283
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPA 241
V++ + + S + +S +AS S P T +G+TP
Sbjct: 3284 TSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPT-STYSEGSTP- 3341
Query: 242 PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPA 301
+ + + + P SE+S+ ++ + TP + +AS + S P
Sbjct: 3342 -------LTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS---TEASLSPTTAEGTSIPT 3391
Query: 302 KESPRKGAAP--APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 359
SP +G P + P T P V+ E + S+ DS + S +P +
Sbjct: 3392 -SSPSEGTTPLASMPVSTTPVVS-------SEVNTLSTTPVDSNTLVTTSTEAS-SSPTI 3442
Query: 360 RAASAPAKESPRKGAAPAP--PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 417
++ + +G+ P P T P A+ E S S+ D+ +
Sbjct: 3443 AEGTSLPTSTTSEGSTPLSIMPLSTTPVAS-------SEASTLSTTPVDTSTPVTTS--- 3492
Query: 418 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSD 477
P SP ++M G+G+ P+ V TP A SE+S+ ++
Sbjct: 3493 ---SPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS-TTPVA-------SSEASTLSTTP 3541
Query: 478 SSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEES 537
T+ + A + S+P++G + + + + + +SE+S S
Sbjct: 3542 VDSNTFVTSSSQASSSPATLQVTTMRMSTPSEG----SSSLTTMLLSSTYVTSSEASTPS 3597
Query: 538 SDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATS 597
+ S D T + + P P+ P T + S + + V T S
Sbjct: 3598 TPSVDRSTPVTTSTQSNSTPT--PPEVITLPMSTPSEVSTPLTIMPVST-----TSVTIS 3650
Query: 598 PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS 657
AG++ + T P S+ S E T + + P +GS
Sbjct: 3651 EAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIW-----------------TPSEGS 3693
Query: 658 LGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANP 717
T PV + T+V + SE S ++P+ V ++ T +A
Sbjct: 3694 TPLTTMPV-------STTRVTS-----SEGS--------TLSTPSVVTSTPVTTSTEAIS 3733
Query: 718 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV--GK 775
++A S ++S P ++ T P R P++ST S+PSV
Sbjct: 3734 SSATLDSTTMSVSMPMEISTLGTTIL----VSTTPVTRFPESST------PSIPSVYTSM 3783
Query: 776 AVATAAQAQTGPEEDSGSSEEESDSEEEAETL---AQVKPSGKTHQIRAALAPAKESPRK 832
++ TA++ + P G++ + E TL + P + ++P++ S
Sbjct: 3784 SMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPI-------SVMSPSEAS--- 3833
Query: 833 GAAPTPPGKTGPSAAQAGKQDDSGSSSEES------DSDGEAP----------------A 870
TPPG T + K +E + S+ P A
Sbjct: 3834 -TLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGA 3892
Query: 871 AVTSAQVIKPPLIF---VDPNRSPAGPAATPAQAQA---ASTPRKARASESTARSSSSES 924
++ S + F D +P P AT STP ST +SS+
Sbjct: 3893 SIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSST-- 3950
Query: 925 EDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ 984
DV PAT T + T V+T + + + SSS ++ S K+ PA
Sbjct: 3951 --ADVFPAT---TGAVSTPVIT--------STELNTPSTSSSSTTTSFSTTKEFTTPAM- 3996
Query: 985 VSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKG 1044
+ PLT + P RT S G ++ TL ATS TS
Sbjct: 3997 -----TTAAPLTYVTM--------STAPSTPRT-TSRGCTTSASTLSATSTPHTS----- 4037
Query: 1045 TNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTE 1104
T+ +P P SS+ S S+ +S P AH+ PT S +
Sbjct: 4038 TSVTTRPVTP----------SSESSRPSTITSHTI------PPTFPPAHSSTPPTTSASS 4081
Query: 1105 TLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1164
T V A + +++ +T P N+ K+ P S+P+V T D
Sbjct: 4082 TTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNT-TIKSNP--TSTPTVPRTTTCFGD 4138
Score = 75.9 bits (185), Expect = 3e-13
Identities = 185/905 (20%), Positives = 315/905 (34%), Gaps = 128/905 (14%)
Query: 467 DSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK 526
+S ++SE +SDS T + P+ + + + T P P +++ + +
Sbjct: 114 ESRTTSESTSDS------TTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTA 167
Query: 527 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASA--------- 577
P+ + E+ + D T A + P P++ PK TN+ S
Sbjct: 168 PLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTT--PESTTIPKSTNSEGSTPLTSMPAST 225
Query: 578 -KVA----------------PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 620
KVA PV + QA TA P+ S+ A +GG+ P S
Sbjct: 226 MKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGS-TPLTRMPLSV 284
Query: 621 ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP-VLPGKTGPTVTQVKA 679
E + L+ T A ++PV S ++P G + PT T +
Sbjct: 285 MLVVSSEASTLSTTPA------------ATNIPVITSTEASSSPTTAEGTSIPTSTYTEG 332
Query: 680 EKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 737
S S+ + SE + S V TS T + PS+ T + ++T
Sbjct: 333 STPLTSTPASTMPVATSEMSTLSITPVDTSTLVT-------TSTEPSSLPTTAEATSMLT 385
Query: 738 AAAQAKQRSPSKVKPPVRNPQNSTVL-----ARGPASVPSVGKA-VATAAQAQTGPEEDS 791
+ S+ P+ N ST+L A +++P K V TA++A + P
Sbjct: 386 STL-------SEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAE 438
Query: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGK-----TGPSA 846
+S S E + L + S P S + TP T A
Sbjct: 439 DTSIATSTPSEGSTPLTSMPVS---------TTPVASSEASNLSTTPVDSKTQVTTSTEA 489
Query: 847 AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAST 906
+ + + S + S+G P +TS V P+ + + P T + +T
Sbjct: 490 SSSPPTAEVNSMPTSTPSEGSTP--LTSMSVSTMPVASSEASTLSTTPVDT---STPVTT 544
Query: 907 PRKARASESTARSSS--SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 964
+A +S +T +S + + E P T P VV+ + P S +
Sbjct: 545 SSEASSSSTTPEGTSIPTSTPSEGSTPLTN--MPVSTRLVVSSEASTTSTTPADSNTFVT 602
Query: 965 SSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVD 1024
+S E+S S EG + S + +T ++ +SEA T ++ VD
Sbjct: 603 TSSEAS--SSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEAS-----TLSTTPVD 655
Query: 1025 SAVGTLPATSPQSTSVQAKGTNK------------LRKPKLPEVQQATKAPESSDDSEDS 1072
S +T S+S A+GT+ P + +++A S D+
Sbjct: 656 SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDT 715
Query: 1073 SDSSSGSEEDGEGPQGAKSAHTLVGPTPSR-----TETLVEETAAESSEDDVVAPSQSLL 1127
S + S E P A A ++ TPS T V +T SSE ++ +
Sbjct: 716 STPVTTSTEASSSPTTADGA-SMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDT 774
Query: 1128 SGYMTPGLTPANS-QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGG 1186
S ++T + S ++ T S+PS S L P+ + +P
Sbjct: 775 STHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSN 834
Query: 1187 KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTEL 1246
+ T S P +G P ++ ++ +T P++ V S + L+
Sbjct: 835 SPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTS------MPVSTTLVATSAISTLSTT 888
Query: 1247 LEQERKKVVDTTKESS---RKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1303
V ++T+ S S G+ T + + E S +P
Sbjct: 889 PVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATP 948
Query: 1304 EKTST 1308
TST
Sbjct: 949 VDTST 953
Score = 75.5 bits (184), Expect = 3e-13
Identities = 171/846 (20%), Positives = 290/846 (34%), Gaps = 113/846 (13%)
Query: 454 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 513
P T S Q ES++ S +S+G P PA + + ++P +
Sbjct: 187 PLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPV----E 242
Query: 514 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA--------MTAAQAKPALKIPQTK 565
+ PV + +A +E S+ + P + +++A P
Sbjct: 243 ISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAAT 302
Query: 566 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVA-GGTQRPAEDSSSSEESDS 624
P T+T AS+ GT P T+T GS+P + + P S S S +
Sbjct: 303 NIPVITSTEASSSPTTAE-GTSIP----TSTYTEGSTPLTSTPASTMPVATSEMSTLSIT 357
Query: 625 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 684
+ + L T + S+ + A+ + +L +G+ P+ T V+ + E
Sbjct: 358 PVDTSTLVTTSTEPSSLPTTAE---ATSMLTSTLSEGSTPL----TNMPVSTILVASSEA 410
Query: 685 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 744
S +S DS+ + ++ +S T A+ A PS T V T + +
Sbjct: 411 STTSTIPVDSKTFVTTASEASSS--PTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSE 468
Query: 745 RSPSKVKPPVRNPQNSTVLARG-----------PASVPSVGKAVATAAQAQTGP---EED 790
S P Q +T P S PS G T+ T P E
Sbjct: 469 ASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEA 528
Query: 791 SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAP-------------- 836
S S D+ T ++ S T + + +P +G+ P
Sbjct: 529 STLSTTPVDTSTPVTTSSEASSSSTTPE---GTSIPTSTPSEGSTPLTNMPVSTRLVVSS 585
Query: 837 -TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEA-PAAVTSAQVIKPPLIFVDPNRSPAGP 894
T P+ + S +SS + ++G + P + S + + V +
Sbjct: 586 EASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSE 645
Query: 895 AATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTP----GIRTNVVTMPTA 950
A+T + S ++E+T+ S+++E T+ TP + T +V A
Sbjct: 646 ASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEA 705
Query: 951 HP-RIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASE 1009
P + ++S E+S S +G + S + S PLT + +SE
Sbjct: 706 STLSTTPVDTSTPVTTSTEAS--SSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSE 763
Query: 1010 AQPPVARTQPSSGVDSAVGTLPATSPQST-------SVQAKGTNKLRKPKL-------PE 1055
A ++ T + T + SP +T S ++G+ L + PE
Sbjct: 764 AS-TLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPE 822
Query: 1056 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQ----------------------GAKSAH 1093
+ P S+ +S S S EG A SA
Sbjct: 823 ASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAI 882
Query: 1094 TLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDS-S 1152
+ + TP T T V + E+ + S+ + G TP S TP + S +
Sbjct: 883 STLSTTPVDTSTPV-TNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEA 941
Query: 1153 PSVSSTLAAKDDP---DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG-AGNP 1208
++S+T P + + P A G P + E GTTP S N
Sbjct: 942 RTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSE---GTTPLTSTPVSHTLVANS 998
Query: 1209 QASTLA 1214
+ASTL+
Sbjct: 999 EASTLS 1004
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 115 bits (287), Expect = 4e-25
Identities = 205/1057 (19%), Positives = 354/1057 (33%), Gaps = 131/1057 (12%)
Query: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLG 114
QT + KR + + KK S+ I+ S E +E+ + ++ S++SS
Sbjct: 86 QTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSS-------SSSSSSTI 138
Query: 115 ADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETE 174
+ SS A E +K K ++ K R +P+ +V E
Sbjct: 139 RKIKSSKNSAANRELQKKLKVKDN----------------KKNRTKKKPTPKPPVVDE-- 180
Query: 175 EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTP 234
A G+ + G ++ DTS++ +V S KI + + P P
Sbjct: 181 -----------AGSGLDN-GDFKVTTPDTSTTQHN---KVSTSPKITTAKPIN-PRPSLP 224
Query: 235 GKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL-----LQAKASG 289
T + ++ + +E + ++ + S+D +E+T +AK AK
Sbjct: 225 PNSDTSK---ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 281
Query: 290 KTSQVGAASAPAKESPRKGAA---PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 346
TS+V A P E+ KG A P P T P + K + S + +E A
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 347 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSRSSS 402
P K + P+ A + + +P PAP PA + K+ +
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 403 EESDSDREALAAMNAAQVKPLGKSP---QVKPASTMGMGP---LGKGAGPVPPGKVGPAT 456
+ +E K P +PA T P K P P + P T
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461
Query: 457 PSAQV-GKWEEDSESSSEESSDSSDGEVPTAV---APAQEKSLGNI-LQAKPTSS--PAK 509
P +E S ++ +E + ++ PT AP KS + PT++ PA
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521
Query: 510 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 569
P++ P + A + + + + PA T + P PK
Sbjct: 522 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 581
Query: 570 KTNTTASAKVAPVRVGTQAPR----------KAGTATSPAGSSP----AVAGGTQRPAED 615
K T K+AP AP + T T+P +P A A T +
Sbjct: 582 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 641
Query: 616 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 675
++ E + + ++ A + KG P AP P K P
Sbjct: 642 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---------APTTPKKPAPKEL 692
Query: 676 QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKV 735
K+ S + ++ + + +P K T + P + +A T+ P
Sbjct: 693 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAPTTLKEPAPT 751
Query: 736 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE 795
K+ +P+ K P + + P+ K A + P + E
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT----TPE 807
Query: 796 EESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS 855
+ E T K H+ +P + +P A PTP
Sbjct: 808 TPPPTTSEVSTPTTTKEPTTIHK-----SPDESTPELSAEPTP----------------- 845
Query: 856 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS---TPRKARA 912
+ E S + P T A KP + +++ T + A+ T A
Sbjct: 846 -KALENSPKEPGVPTTKTPA-ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 903
Query: 913 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA--GASSSKESS 970
+E T S + + + TQ TP + T+ T +APK + ++++ +
Sbjct: 904 TEKTTESKITATTTQVTSTTTQDTTP---FKITTLKTT--TLAPKVTTTKKTITTTEIMN 958
Query: 971 RISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTL 1030
+ + K + AT P T+A K + K + P V + + + T+
Sbjct: 959 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTM 1018
Query: 1031 PATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
P +P S +A R + P + P+S D
Sbjct: 1019 PELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSED 1055
Score = 100 bits (250), Expect = 8e-21
Identities = 215/1013 (21%), Positives = 352/1013 (34%), Gaps = 120/1013 (11%)
Query: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA------AAQVQVGKQE 395
+E P S KAP AS K + ++ P +KT + V + +
Sbjct: 64 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ 123
Query: 396 EDSRSSSEESDSD--REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 453
E S SSS S S R+ ++ N+A + L K +VK K P
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK--------KNRTKKKPTPKP 175
Query: 454 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 513
P A G D + ++ ++S + +V T+ K + P S +K
Sbjct: 176 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 235
Query: 514 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK---PALKIPQTKACPKK 570
E N ++S + + S + ++ AK P K+ K PK
Sbjct: 236 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV-LAKPTPKA 294
Query: 571 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP-AVAGGTQRPAEDSSSSEESDSEEEKT 629
TT + + T K +T+P +P + P E + ++ +S K
Sbjct: 295 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 354
Query: 630 GLAVTVGQ-----AKSVGKGLQVKAASVPVKG--SLGQGTAPVLPGKTGPTVTQVKA--E 680
T + K + A K + + AP P K PT + A
Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414
Query: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 740
+E + ++ +E +P K K P + P A T P T
Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP-APTTPKEPAPTTT--- 470
Query: 741 QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--- 797
K+ SP+ K P S A + A T A T P+E S ++ +E
Sbjct: 471 --KEPSPTTPKEPAPTTTKS-------APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521
Query: 798 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--RKGAAPTPPGKTGP-----SAAQAG 850
+ +E A T + KP+ T + A P + +P K APT P + P +A
Sbjct: 522 TTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580
Query: 851 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN-RSPAGPAATPAQAQAASTPRK 909
K+ + + + + E PA T ++ P +P +P PA T +A A +TP++
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638
Query: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM----PTAHPRIAPKASMAGASS 965
+ + ++ E P T T T+ PT + APK +A ++
Sbjct: 639 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTT 697
Query: 966 SKESSRISDGKKQEGP--ATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGV 1023
+ +S D P + K PA + A A A T P
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 757
Query: 1024 DSAVGTLPATSPQSTSVQ--AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEE 1081
+ P ST+ A T K P P+ + A P+ + + + SE
Sbjct: 758 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK-EPAPTTPKKPAPTTPETPPPTTSE- 815
Query: 1082 DGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTP-GLTPANS 1140
+ PT ++ T + ++ ES+ + LS TP L +
Sbjct: 816 -------------VSTPTTTKEPTTIHKSPDESTPE---------LSAEPTPKALENSPK 853
Query: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1200
+ T K ++ T AKD +++ + +PK KE A TT +K+ +
Sbjct: 854 EPGVPTTKTPAATKPEMTTTAKDKTT-ERDLRTTPETTTAAPKM-TKETA--TTTEKTTE 909
Query: 1201 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1260
K A Q ++ Q P+ + + KV T KK + TT E
Sbjct: 910 SKITATTTQVTSTTTQDT-------TPFKITTLKTTTLAPKVTT------TKKTI-TTTE 955
Query: 1261 SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1313
K E+ K K A TP+ +K K +P+K ++T K K
Sbjct: 956 IMNKPEETAKPKDRATNSKATTPKPQKPTK-----------APKKPTSTKKPK 997
Score = 97.4 bits (241), Expect = 8e-20
Identities = 196/1029 (19%), Positives = 341/1029 (33%), Gaps = 120/1029 (11%)
Query: 234 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQ 293
P P P G + + S TK P+ ++ +++ +SEE T ++S +S
Sbjct: 73 PSSKKAPPPSGASQTIKSTTKRS-PKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 131
Query: 294 VGAASAPAK-------------------ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 334
++S K + +K P P V +A +G D +
Sbjct: 132 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 191
Query: 335 SSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 391
++ ++ + + P + K R + P ++ ++ + T
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 251
Query: 392 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK---SPQVKPASTMGMGPLGKGAGPVP 448
KQ S + +++ +A + P K P K +T KG
Sbjct: 252 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT------KGPALTT 305
Query: 449 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI-LQAKPTSSP 507
P + P TP ++ ++ +S+ ++ P AP KS + PT++
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTT----PKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 508 AKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA-DSEEAPAAMTAAQAKPALKIPQTKA 566
P P K P + + A + + PA T + P T
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 421
Query: 567 CPKK--TNTTASAKVAPVRVGTQAPRKAGTAT--SPAGSSPAVAGGTQRPAEDSSSSEES 622
PK+ T A P AP+K T PA ++P T ++ +E
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481
Query: 623 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS--LGQGTAPVLPGKTGPTVTQVKAE 680
K+ T A + K A + P + S + AP P + PT + A
Sbjct: 482 APTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA- 536
Query: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 740
+ E A +P + + K A P + K T K +T
Sbjct: 537 ---------PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 741 QAKQRSPSKVKPPVRNPQN--STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 798
K + KP P+ T + P A A P+E + ++ +E
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647
Query: 799 DSEEEAETLAQVKPSGKTHQIRAALAPAKESPR--KGAAPTPPGKTGPS--AAQAGKQDD 854
E P+ T + A P +P K APT P K P A K+
Sbjct: 648 APTTPKE------PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701
Query: 855 SGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP-NRSPAGPAATPAQAQAASTPRKARAS 913
S + + + + + A T + P +P +P G A T + A +TP+K
Sbjct: 702 STTCDKPAPTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 759
Query: 914 E---STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE-- 968
E +T + +S + D+ P T T PT AP A ++ E
Sbjct: 760 ELAPTTTKGPTSTTSDK----------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 809
Query: 969 ---SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDS 1025
+S +S + P T + K S P A A + S +P V T+
Sbjct: 810 PPTTSEVSTPTTTKEPTT-IHKSPDESTPELSAEPTPKALENSPKEPGVPTTK------- 861
Query: 1026 AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEG 1085
T AT P+ T+ T + PE T AP+ + ++ +++ ++ S+
Sbjct: 862 ---TPAATKPEMTTTAKDKTTERDLRTTPET--TTAAPKMTKETATTTEKTTESKITATT 916
Query: 1086 PQGAKSA-------------HTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMT 1132
Q + T + P + T+ + T + ++ P + T
Sbjct: 917 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 976
Query: 1133 PGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASG 1192
TP + +KA K S+ + + K L+P + EA
Sbjct: 977 ---TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1033
Query: 1193 TTPQKSRKP 1201
TT + ++ P
Sbjct: 1034 TTTRPNQTP 1042
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 115 bits (287), Expect = 4e-25
Identities = 205/1057 (19%), Positives = 354/1057 (33%), Gaps = 131/1057 (12%)
Query: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLG 114
QT + KR + + KK S+ I+ S E +E+ + ++ S++SS
Sbjct: 127 QTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSS-------SSSSSSTI 179
Query: 115 ADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETE 174
+ SS A E +K K ++ K R +P+ +V E
Sbjct: 180 RKIKSSKNSAANRELQKKLKVKDN----------------KKNRTKKKPTPKPPVVDE-- 221
Query: 175 EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTP 234
A G+ + G ++ DTS++ +V S KI + + P P
Sbjct: 222 -----------AGSGLDN-GDFKVTTPDTSTTQHN---KVSTSPKITTAKPIN-PRPSLP 265
Query: 235 GKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL-----LQAKASG 289
T + ++ + +E + ++ + S+D +E+T +AK AK
Sbjct: 266 PNSDTSK---ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 322
Query: 290 KTSQVGAASAPAKESPRKGAA---PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 346
TS+V A P E+ KG A P P T P + K + S + +E A
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 347 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSRSSS 402
P K + P+ A + + +P PAP PA + K+ +
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 403 EESDSDREALAAMNAAQVKPLGKSP---QVKPASTMGMGP---LGKGAGPVPPGKVGPAT 456
+ +E K P +PA T P K P P + P T
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502
Query: 457 PSAQV-GKWEEDSESSSEESSDSSDGEVPTAV---APAQEKSLGNI-LQAKPTSS--PAK 509
P +E S ++ +E + ++ PT AP KS + PT++ PA
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 510 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 569
P++ P + A + + + + PA T + P PK
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 622
Query: 570 KTNTTASAKVAPVRVGTQAPR----------KAGTATSPAGSSP----AVAGGTQRPAED 615
K T K+AP AP + T T+P +P A A T +
Sbjct: 623 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 682
Query: 616 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 675
++ E + + ++ A + KG P AP P K P
Sbjct: 683 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---------APTTPKKPAPKEL 733
Query: 676 QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKV 735
K+ S + ++ + + +P K T + P + +A T+ P
Sbjct: 734 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAPTTLKEPAPT 792
Query: 736 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE 795
K+ +P+ K P + + P+ K A + P + E
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT----TPE 848
Query: 796 EESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS 855
+ E T K H+ +P + +P A PTP
Sbjct: 849 TPPPTTSEVSTPTTTKEPTTIHK-----SPDESTPELSAEPTP----------------- 886
Query: 856 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS---TPRKARA 912
+ E S + P T A KP + +++ T + A+ T A
Sbjct: 887 -KALENSPKEPGVPTTKTPA-ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 944
Query: 913 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA--GASSSKESS 970
+E T S + + + TQ TP + T+ T +APK + ++++ +
Sbjct: 945 TEKTTESKITATTTQVTSTTTQDTTP---FKITTLKTT--TLAPKVTTTKKTITTTEIMN 999
Query: 971 RISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTL 1030
+ + K + AT P T+A K + K + P V + + + T+
Sbjct: 1000 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTM 1059
Query: 1031 PATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
P +P S +A R + P + P+S D
Sbjct: 1060 PELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSED 1096
Score = 100 bits (250), Expect = 8e-21
Identities = 215/1013 (21%), Positives = 352/1013 (34%), Gaps = 120/1013 (11%)
Query: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA------AAQVQVGKQE 395
+E P S KAP AS K + ++ P +KT + V + +
Sbjct: 105 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ 164
Query: 396 EDSRSSSEESDSD--REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 453
E S SSS S S R+ ++ N+A + L K +VK K P
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK--------KNRTKKKPTPKP 216
Query: 454 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 513
P A G D + ++ ++S + +V T+ K + P S +K
Sbjct: 217 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 276
Query: 514 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK---PALKIPQTKACPKK 570
E N ++S + + S + ++ AK P K+ K PK
Sbjct: 277 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV-LAKPTPKA 335
Query: 571 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP-AVAGGTQRPAEDSSSSEESDSEEEKT 629
TT + + T K +T+P +P + P E + ++ +S K
Sbjct: 336 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 395
Query: 630 GLAVTVGQ-----AKSVGKGLQVKAASVPVKG--SLGQGTAPVLPGKTGPTVTQVKA--E 680
T + K + A K + + AP P K PT + A
Sbjct: 396 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455
Query: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 740
+E + ++ +E +P K K P + P A T P T
Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP-APTTPKEPAPTTT--- 511
Query: 741 QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--- 797
K+ SP+ K P S A + A T A T P+E S ++ +E
Sbjct: 512 --KEPSPTTPKEPAPTTTKS-------APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 798 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--RKGAAPTPPGKTGP-----SAAQAG 850
+ +E A T + KP+ T + A P + +P K APT P + P +A
Sbjct: 563 TTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621
Query: 851 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN-RSPAGPAATPAQAQAASTPRK 909
K+ + + + + E PA T ++ P +P +P PA T +A A +TP++
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679
Query: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM----PTAHPRIAPKASMAGASS 965
+ + ++ E P T T T+ PT + APK +A ++
Sbjct: 680 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTT 738
Query: 966 SKESSRISDGKKQEGP--ATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGV 1023
+ +S D P + K PA + A A A T P
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 798
Query: 1024 DSAVGTLPATSPQSTSVQ--AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEE 1081
+ P ST+ A T K P P+ + A P+ + + + SE
Sbjct: 799 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK-EPAPTTPKKPAPTTPETPPPTTSE- 856
Query: 1082 DGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTP-GLTPANS 1140
+ PT ++ T + ++ ES+ + LS TP L +
Sbjct: 857 -------------VSTPTTTKEPTTIHKSPDESTPE---------LSAEPTPKALENSPK 894
Query: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1200
+ T K ++ T AKD +++ + +PK KE A TT +K+ +
Sbjct: 895 EPGVPTTKTPAATKPEMTTTAKDKTT-ERDLRTTPETTTAAPKM-TKETA--TTTEKTTE 950
Query: 1201 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1260
K A Q ++ Q P+ + + KV T KK + TT E
Sbjct: 951 SKITATTTQVTSTTTQDT-------TPFKITTLKTTTLAPKVTT------TKKTI-TTTE 996
Query: 1261 SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1313
K E+ K K A TP+ +K K +P+K ++T K K
Sbjct: 997 IMNKPEETAKPKDRATNSKATTPKPQKPTK-----------APKKPTSTKKPK 1038
Score = 97.4 bits (241), Expect = 8e-20
Identities = 196/1029 (19%), Positives = 341/1029 (33%), Gaps = 120/1029 (11%)
Query: 234 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQ 293
P P P G + + S TK P+ ++ +++ +SEE T ++S +S
Sbjct: 114 PSSKKAPPPSGASQTIKSTTKRS-PKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 172
Query: 294 VGAASAPAK-------------------ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 334
++S K + +K P P V +A +G D +
Sbjct: 173 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 232
Query: 335 SSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 391
++ ++ + + P + K R + P ++ ++ + T
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 292
Query: 392 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK---SPQVKPASTMGMGPLGKGAGPVP 448
KQ S + +++ +A + P K P K +T KG
Sbjct: 293 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT------KGPALTT 346
Query: 449 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI-LQAKPTSSP 507
P + P TP ++ ++ +S+ ++ P AP KS + PT++
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTT----PKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 508 AKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA-DSEEAPAAMTAAQAKPALKIPQTKA 566
P P K P + + A + + PA T + P T
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 462
Query: 567 CPKK--TNTTASAKVAPVRVGTQAPRKAGTAT--SPAGSSPAVAGGTQRPAEDSSSSEES 622
PK+ T A P AP+K T PA ++P T ++ +E
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522
Query: 623 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS--LGQGTAPVLPGKTGPTVTQVKAE 680
K+ T A + K A + P + S + AP P + PT + A
Sbjct: 523 APTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA- 577
Query: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 740
+ E A +P + + K A P + K T K +T
Sbjct: 578 ---------PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 741 QAKQRSPSKVKPPVRNPQN--STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 798
K + KP P+ T + P A A P+E + ++ +E
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688
Query: 799 DSEEEAETLAQVKPSGKTHQIRAALAPAKESPR--KGAAPTPPGKTGPS--AAQAGKQDD 854
E P+ T + A P +P K APT P K P A K+
Sbjct: 689 APTTPKE------PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742
Query: 855 SGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP-NRSPAGPAATPAQAQAASTPRKARAS 913
S + + + + + A T + P +P +P G A T + A +TP+K
Sbjct: 743 STTCDKPAPTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 800
Query: 914 E---STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE-- 968
E +T + +S + D+ P T T PT AP A ++ E
Sbjct: 801 ELAPTTTKGPTSTTSDK----------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 850
Query: 969 ---SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDS 1025
+S +S + P T + K S P A A + S +P V T+
Sbjct: 851 PPTTSEVSTPTTTKEPTT-IHKSPDESTPELSAEPTPKALENSPKEPGVPTTK------- 902
Query: 1026 AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEG 1085
T AT P+ T+ T + PE T AP+ + ++ +++ ++ S+
Sbjct: 903 ---TPAATKPEMTTTAKDKTTERDLRTTPET--TTAAPKMTKETATTTEKTTESKITATT 957
Query: 1086 PQGAKSA-------------HTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMT 1132
Q + T + P + T+ + T + ++ P + T
Sbjct: 958 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 1017
Query: 1133 PGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASG 1192
TP + +KA K S+ + + K L+P + EA
Sbjct: 1018 ---TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1074
Query: 1193 TTPQKSRKP 1201
TT + ++ P
Sbjct: 1075 TTTRPNQTP 1083
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 113 bits (283), Expect = 1e-24
Identities = 144/638 (22%), Positives = 240/638 (37%), Gaps = 112/638 (17%)
Query: 465 EEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA 524
EE+ E+ EE + GE +E++ G + K + P+K V+ +A
Sbjct: 473 EEEKEAKEEEGKEEEGGE--------EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA 524
Query: 525 EKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRV 584
+ P + +E + S ++P + + A P+ K+ P+K + A+V
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS-PEKEEAKSPAEV----- 578
Query: 585 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 644
++P KA + SPA A ++ S EE+ S E
Sbjct: 579 --KSPEKAKSPAKEEAKSPAEAKSPEKAK--SPVKEEAKSPAE----------------- 617
Query: 645 LQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE-EESDSEEAAASPAQ 703
A PVK + A V + + T+ +A+ E ++S E EE+ S E A SP
Sbjct: 618 -----AKSPVKEE-AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP-- 669
Query: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
VK K + +P A A S + S + + +SP K K PV+ S
Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSP--------VKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
A+ P K A + P ++ S E++ S E+A+TL P KT A
Sbjct: 722 AKSPV------KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775
Query: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
+PA + P K +P P A++ ++D+ + +E E
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV--------------- 820
Query: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
+SP P + + P+KA ++ A + E +D A + P
Sbjct: 821 -----KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAP----- 870
Query: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
P++ K A KES + KK+E + KK P A ++V
Sbjct: 871 -------KPKVEEKKEPA-VEKPKESK--VEAKKEE---AEDKKKVPTPEKEAPAKVEVK 917
Query: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPA-TSPQSTSVQAKGTNKLRKPKLPEVQQATKA 1062
+ + VA+ +P D A P+ + + + K K K K PE + T+A
Sbjct: 918 EDAKPKEKTEVAKKEP----DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEA 973
Query: 1063 PESSDD-----------SEDSSDSSSGSEEDGEGPQGA 1089
DD +E + SSS ++D + P+ A
Sbjct: 974 KAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011
Score = 110 bits (276), Expect = 7e-24
Identities = 161/628 (25%), Positives = 255/628 (40%), Gaps = 104/628 (16%)
Query: 49 IYTHWQQTSELGRK--RKAEEDAAL---QAKKTRVSDPISTSESSE------------EE 91
+ TH + SE K K+E++ + Q ++T+V++ ++ E E EE
Sbjct: 432 VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491
Query: 92 EEAEA--ETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVA 149
EEAE E K+ P + + + S +KE+AK+ E PA K+
Sbjct: 492 EEAEGGEEETKSPPAEEAASPE---KEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548
Query: 150 NLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSA-GQADSSSEDTSSSSD 208
S + P A + E + V + A P A A++ S + + S
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608
Query: 209 ETDVEVKASEKILQVRAASAPAK-GTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 267
+ + + A K A +PA+ +P K +P S KA PE++ S E
Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE----EAKSPEKAKSPEKEEAKSPE 664
Query: 268 ESSD---SEEETPAAKALLQAKASGKTSQVGAASAPAKE---SPRKGAAPAPPGKTGPAV 321
++ +E ++P KA KA K+ + A +P KE SP K +P P
Sbjct: 665 KAKSPVKAEAKSP-EKAKSPVKAEAKSPE--KAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 322 AKA----QAGKREEDSQSSSEESDSEEEA--PAQAK------PSGKAPQVRAASAPAKES 369
AK+ +A E+ EE+ S E+A P +AK P K P A +PA +
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781
Query: 370 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
P K +P P A+ + +ED+++ +E E + VK K +V
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPL---KEDAKAPEKEIPKKEEV-----KSPVKEEEKPQEV 833
Query: 430 KPASTMGMGPLGKGAGPVPPGKV----GPATPSAQVGKWEEDSESSSEES--SDSSDGEV 483
K PP K PATP K EE +S EE+ ++ +V
Sbjct: 834 KVKE--------------PPKKAEEEKAPATP-----KTEEKKDSKKEEAPKKEAPKPKV 874
Query: 484 PTAVAPAQEKSLGNILQAKPTSSPAK---GPPQKAGPVAVQVKAE-KPMDNSESSEESSD 539
PA EK + ++AK + K P+K P V+VK + KP + +E +++ D
Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 540 SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT-TASAKVAPVRVGTQAPRKAGTAT-S 597
A ++E +KPA K +A P+K +T AK + T+A K T S
Sbjct: 935 DAKAKE--------PSKPAEK---KEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983
Query: 598 PAGSSPAVAGGTQRPAEDSSSSEESDSE 625
S P AE SSS+++ DS+
Sbjct: 984 KEPSKPKA-----EKAEKSSSTDQKDSK 1006
Score = 107 bits (267), Expect = 8e-23
Identities = 150/693 (21%), Positives = 258/693 (37%), Gaps = 106/693 (15%)
Query: 163 PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQ 222
PS +T + ++EE+ + + K ++ Q + + + T ++E + E K E +
Sbjct: 430 PSVSTHIKVKSEEK--IKVVEKSEKETVIVEEQTEET-QVTEEVTEEEEKEAKEEEGKEE 486
Query: 223 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 282
A+G G+ T +PP + A + +E+++S +E S +EE + +
Sbjct: 487 EGGEEEEAEG--GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV 544
Query: 283 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDS 342
+ + ++ A S P +SP K A +P P AK+ A ++ S E+ S
Sbjct: 545 KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA----KEEAKSPAEAKS 600
Query: 343 EEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 402
E+A + K K+P A +P KE + A P K + + + E+
Sbjct: 601 PEKAKSPVKEEAKSP--AEAKSPVKEEAKSPAEVKSPEK-AKSPTKEEAKSPEKAKSPEK 657
Query: 403 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 462
EE+ S +A + VK KSP+ K PV P
Sbjct: 658 EEAKSPEKA-----KSPVKAEAKSPE-------------KAKSPVKAEAKSP-------- 691
Query: 463 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 522
E ++S +E + S + A +P +E++ P AK P + PV +
Sbjct: 692 ---EKAKSPVKEEAKSPE----KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 523 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 582
K+ + + E ++ + + PA A PA K P+ AK +PV
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEA--RSPADKFPE------------KAK-SPV 789
Query: 583 RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG 642
+ ++P KA SP ED+ + E+ ++E+ V K
Sbjct: 790 KEEVKSPEKA--------KSPL--------KEDAKAPEKEIPKKEEVKSPV-----KEEE 828
Query: 643 KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPA 702
K +VK P K + A P + K K+E++ E E PA
Sbjct: 829 KPQEVKVKEPPKKAEEEKAPAT-------PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Query: 703 QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV 762
K K +AK A K + P K A + K+ + K K V +
Sbjct: 882 VEKPKESKVEAKKEEA-----EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936
Query: 763 LARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAA 822
A+ P+ A + + PE+ E+ EE+ +T A+ K KT +
Sbjct: 937 KAKEPSK---------PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPS 987
Query: 823 LAPAKESPRKGAA----PTPPGKTGPSAAQAGK 851
A+++ + + PP K A GK
Sbjct: 988 KPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 101 bits (252), Expect = 4e-21
Identities = 137/673 (20%), Positives = 252/673 (37%), Gaps = 95/673 (14%)
Query: 734 KVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA----AQAQTGPEE 789
K+ + + K +S K+K V + TV+ V + V A+ + G EE
Sbjct: 428 KIPSVSTHIKVKSEEKIKV-VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 790 DSGSSEEESDSEEE-----AETLAQVKPSGKTHQIRAALAPAK-ESPRKGAAPTPPGKTG 843
+ G EE EEE AE A + K+ A +PA+ +SP K A +P
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 844 PSAAQAGKQDDSGSSSEESDSDGE---APAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900
P A++ ++++ S E + E +PA V S + K P A +PA+
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA---------KEEAKSPAE 597
Query: 901 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM 960
A++ + E+ + + + E+ + +P PT +P+ +
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP----EKAKSPTKEEAKSPEKA- 652
Query: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1020
S E +K + P + K+P ++ +K A+ +A+ PV S
Sbjct: 653 ----KSPEKEEAKSPEKAKSPV-KAEAKSPEK---AKSPVKAEAKSPEKAKSPVKEEAKS 704
Query: 1021 SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE 1080
P + +AK K + P V++ K PE + S +
Sbjct: 705 ----------PEKAKSPVKEEAKSPEKAKSP----VKEEAKTPEKA---------KSPVK 741
Query: 1081 EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1140
E+ + P+ AKS P ++T + A ++++ +P+ +P S
Sbjct: 742 EEAKSPEKAKS------PEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS 795
Query: 1141 QASKATPKLDSSPSVSSTLAAKDDPDG--KQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1198
+P + + + + K++ K+E KPQ+ PK +E A T +
Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855
Query: 1199 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1258
+K K P+ P P E + + +V K +E ++++ D
Sbjct: 856 KKDSKKEEAPKKEA--------------PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901
Query: 1259 KESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDK 1318
K + + K ++ D + K+K ++ E +A K A K
Sbjct: 902 KVPTPEKEAPAKVEVKEDA------KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKK 955
Query: 1319 ASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEK 1378
+ + K KK + ++ E ++ L K + S PK++K +K S +KD +
Sbjct: 956 DTKEEKAKKPEEKPKTEAKAKEDDKTLSK--------EPSKPKAEKAEKSSSTDQKDSKP 1007
Query: 1379 KEKKKKAKKASTK 1391
EK + K A K
Sbjct: 1008 PEKATEDKAAKGK 1020
Score = 92.8 bits (229), Expect = 2e-18
Identities = 130/573 (22%), Positives = 224/573 (39%), Gaps = 87/573 (15%)
Query: 674 VTQVKAEKQEDSESSEEESDSE---------------EAAASPAQVKTSVKKTQAKANPA 718
VT+ + ++ ++ E EEE E E AASP + S K +AK +PA
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAK-SPA 528
Query: 719 AARAPSAKGTISAPGKVVT-AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 777
A++P K +P +V + A++ + +K P ++P+ A+ PA V S KA
Sbjct: 529 EAKSPE-KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE--AKSPAEVKSPEKAK 585
Query: 778 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK-ESPRKGAAP 836
+ A + P E + +S +EEA++ A+ K K A +PA+ +SP K +P
Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK----EEAKSPAEVKSPEKAKSP 641
Query: 837 TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 896
T P A++ +++++ S E++ S +A A +SP A
Sbjct: 642 TKEEAKSPEKAKSPEKEEA-KSPEKAKSPVKAEA------------------KSPE-KAK 681
Query: 897 TPAQAQAASTPRKARA--SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI 954
+P +A+A S P KA++ E ++S ++ + + ++ T A +
Sbjct: 682 SPVKAEAKS-PEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740
Query: 955 APKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPV 1014
+A + S E ++ D K P + K A P + K + E + P
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVK---SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797
Query: 1015 ARTQP-SSGVDSAVGTLP----ATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDS 1069
P + +P SP + + PK E ++A P+ +++
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK-TEEK 856
Query: 1070 EDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG 1129
+DS + +E + K + P S+ E EE +ED P
Sbjct: 857 KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE-----AEDKKKVP------- 904
Query: 1130 YMTPGLTPANSQASKATPKLDSSPSVSSTLAAK--DDPDGKQEAKPQQAAGMLSPKTGGK 1187
TP +K K D+ P + +A K DD K+ +KP + K
Sbjct: 905 ------TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK----------K 948
Query: 1188 EAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1220
EAA K K KK P+ A + + T
Sbjct: 949 EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Score = 78.6 bits (192), Expect = 4e-14
Identities = 110/522 (21%), Positives = 204/522 (39%), Gaps = 72/522 (13%)
Query: 946 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ 1005
++P P+I P S S+E ++ + ++E + + TQ +V +
Sbjct: 421 SLPEGLPKI-PSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEE------TQVTEEVTEE 473
Query: 1006 KASEAQPPVARTQPSSGVDSAVG------TLPATSPQSTSVQAKGTNKLR-----KPKLP 1054
+ EA+ + + + A G + PA S +AK K + K P
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Query: 1055 EVQQA-----TKAPESS-----DDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTE 1104
E ++A K+PE + ++++ ++ S +E+ + P KS P +
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 1105 TLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1164
+ E + E ++ V ++S +P A S A +P+ SP+ K++
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEA-KSPVKEEAKSPAEVKSPEKAKSPT-------KEE 645
Query: 1165 PDGKQEAKPQQAAGMLSP-KTGGKEAASGTTPQKSRKPKKG-AGNPQASTLALQSNITQC 1222
++AK + SP K A +P+K++ P K A +P+ + ++
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Query: 1223 LLGQPWPLNEA---QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPA 1279
+ EA + S VK + E+ + V + K + + + L P
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765
Query: 1280 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAK------------------------ 1315
A+TP +K++ + A + E + SP K S KAK
Sbjct: 766 AKTP-AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 1316 -RDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKK 1374
++ +VK K+ + A P+ E +K E + PK K E+KK +K
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 1375 DKE-----KKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1411
KE KKE+ + KK T + E+P++ + K+ K E+T
Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT 926
Score = 45.4 bits (106), Expect = 4e-04
Identities = 44/191 (23%), Positives = 84/191 (43%), Gaps = 13/191 (6%)
Query: 1227 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1286
P+ L E + V ++ +E+ KVV+ +++ + E + ++ +
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 1287 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--KGSLGSQGAKDEPEEE 1344
K+++ EGGE + T A ++A+ KE K K S PE+E
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPA--EEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 1345 LQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKK--------KKAKKASTKDSESP 1396
K V+ +++ + KE+ KS K EK+E K +KAK + ++++SP
Sbjct: 537 EAKSPAEVKSPEKAKSPA-KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 1397 SQKKKKKKKKT 1407
++ K +K K+
Sbjct: 596 AEAKSPEKAKS 606
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 110 bits (276), Expect = 7e-24
Identities = 178/920 (19%), Positives = 303/920 (32%), Gaps = 96/920 (10%)
Query: 201 EDTSSSSDETDVEVKASE-KILQVRAASAPAKGTPGKGATPAPP--------GKAGAVAS 251
++ S D D +V + Q S K T K P P + +
Sbjct: 86 DEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVN 145
Query: 252 QTKAGKPEEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGAASAPAKESPR 306
+ + +E + ++ + S+D +E+T +AK AK TS+V A P E+
Sbjct: 146 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT 205
Query: 307 KGAA---PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 363
KG A P P T P + K + S + +E AP K + P+ A +
Sbjct: 206 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 265
Query: 364 APAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSRSSSEESDSDREALAAMNAAQ 419
+ +P PAP PA + K+ + + +E
Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325
Query: 420 VKPLGKSP---QVKPASTMGMGP---LGKGAGPVPPGKVGPATPSAQV-GKWEEDSESSS 472
K P +PA T P K P P + P TP +E S ++
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385
Query: 473 EESSDSSDGEVPTAV---APAQEKSLGNI-LQAKPTSS--PAKGPPQKAGPVAVQVKAEK 526
+E + ++ PT AP KS + PT++ PA P++ P + A
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445
Query: 527 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT 586
+ + + + PA T + P PKK T K+AP
Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505
Query: 587 QAPR----------KAGTATSPAGSSP----AVAGGTQRPAEDSSSSEESDSEEEKTGLA 632
AP + T T+P +P A A T + ++ E + + ++
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565
Query: 633 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEES 692
A + KG P AP P K P K+ S + ++ +
Sbjct: 566 TPKETAPTTPKGTAPTTLKEP---------APTTPKKPAPKELAPTTTKEPTSTTCDKPA 616
Query: 693 DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 752
+ +P K T + P + +A T+ P K+ +P+ K
Sbjct: 617 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKG 675
Query: 753 PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP 812
P + + P+ K A + P + E + E T K
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT----TPETPPPTTSEVSTPTTTKE 731
Query: 813 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAV 872
H+ +P + +P A PTP + E S + P
Sbjct: 732 PTTIHK-----SPDESTPELSAEPTP------------------KALENSPKEPGVPTTK 768
Query: 873 TSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS---TPRKARASESTARSSSSESEDEDV 929
T A KP + +++ T + A+ T A +E T S + + +
Sbjct: 769 TPA-ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 827
Query: 930 IPATQCLTPGIRTNVVTMPTAHPRIAPKASMA--GASSSKESSRISDGKKQEGPATQVSK 987
TQ TP + T+ T +APK + ++++ ++ + K + AT
Sbjct: 828 STTTQDTTP---FKITTLKTT--TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 882
Query: 988 KNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNK 1047
P T+A K + K + P V + + + T+P +P S +A
Sbjct: 883 TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 942
Query: 1048 LRKPKLPEVQQATKAPESSD 1067
R + P + P+S D
Sbjct: 943 TRPNQTPNSKLVEVNPKSED 962
Score = 103 bits (256), Expect = 2e-21
Identities = 160/769 (20%), Positives = 266/769 (34%), Gaps = 67/769 (8%)
Query: 76 TRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKT 135
T +P ST+ +E T K+ P + P++ KE A T++ T
Sbjct: 219 TTPKEPASTTP-----KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 136 GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQ 195
P P T K A + +P EP A TT PA +P + +
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 332
Query: 196 ADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA 255
++++ + ++ + A PA TP + A P A +
Sbjct: 333 PAPTTKEPAPTTPKEPAPT----------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 382
Query: 256 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
P+E + ++++ + + +E PA A + K PA +P K AP P
Sbjct: 383 TTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTP-KEPAPTTPK 440
Query: 316 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK-PSGKAPQVRAASAPAKESPR--K 372
K P K A ++ ++ +++ AP K P+ P+ A + P K +P +
Sbjct: 441 KPAPTTPKEPAPTTPKEPAPTT----TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 496
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
AP P K P + E+ ++ E + AA +P +P+ +PA
Sbjct: 497 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK-EPA 555
Query: 433 STMGMGP-----------LGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG 481
T P KG P + P TP K E ++ E +S + D
Sbjct: 556 PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDK 614
Query: 482 EVPT---AVAPAQEKSLGNILQAKPTSSPAKG--PPQKAGPVAVQVKAEKPMDNSESSEE 536
PT AP K +P + KG P P K P + + ++ +
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 674
Query: 537 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV--RVGTQAPRKAGT 594
S S++ PA T + P PKK T P V T K T
Sbjct: 675 GPTSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 733
Query: 595 A--TSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA-----VTVGQAKSVGKGLQV 647
SP S+P ++ P +S +E KT A T + K+ + L+
Sbjct: 734 TIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792
Query: 648 KAASVPVKGSLGQGTA----PVLPGKTGPTVTQVKAEKQEDSESSEEES-DSEEAAASPA 702
+ + + TA K T TQV + +D+ + + + A
Sbjct: 793 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852
Query: 703 QVKTSVKKTQAKANPAAA-----RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNP 757
K ++ T+ P RA ++K T P K A + K P VR P
Sbjct: 853 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 912
Query: 758 QNSTVLARGPASVPSV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 803
+ + + +++P + + Q T P + S E + + E
Sbjct: 913 KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 961
Score = 95.9 bits (237), Expect = 2e-19
Identities = 183/948 (19%), Positives = 324/948 (34%), Gaps = 91/948 (9%)
Query: 65 AEEDAALQAKKTRVSDPISTSESSEEEEEAEAET--AKATPRLASTNSSVLGADLPSSMK 122
++E + K+T V +T+ + + + + +T AK T + T++ L K
Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196
Query: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAF 182
KAET G + P +P EP++ T S P
Sbjct: 197 PTPKAETTTKGPALTTPKEP-------------TPTTPKEPASTTPKEPTPTTIKSAPT- 242
Query: 183 GAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP 242
+P + A ++ ++ + ++ + E AP T K A P
Sbjct: 243 -TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP---TTTKSAPTTP 298
Query: 243 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK 302
A + P+E + ++ +E + + + PA A + K A PA
Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 303 ESPRKGAAPAPPGKTGPAVAKAQA---GKREEDSQSSSEESDSEEEAPAQAK---PSGKA 356
+P K AP P + P K + K + + S + ++E AP K + K
Sbjct: 359 TTP-KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417
Query: 357 PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMN 416
P PA +P K AP P+K P + ++ ++ +
Sbjct: 418 PSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK------------ 464
Query: 417 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 476
KP +P+ +PA T K P P K+ P TP E ++ E
Sbjct: 465 ----KPAPTTPK-EPAPT-----TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 514
Query: 477 DSSDGEVPTAVAPAQEKSLGNILQAKPT-SSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 535
+ E PT P + A T PA P++ P + A + +
Sbjct: 515 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 574
Query: 536 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 595
+ + + PA T + P P T P T A P P K
Sbjct: 575 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPAP 633
Query: 596 TSPAGSSPAVAGGTQRPA--EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVP 653
T+P +P GT E + ++ + + +E A + KG + P
Sbjct: 634 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---------LAPTTTKGPTSTTSDKP 684
Query: 654 VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQA 713
+ + TAP P + PT + A + + + SE + + + T++ K+
Sbjct: 685 AP-TTPKETAPTTPKEPAPTTPKKPA---PTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 740
Query: 714 KANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV 773
++ P + P+ K ++P + ++P+ KP + R + P
Sbjct: 741 ESTPELSAEPTPKALENSPKE----PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 796
Query: 774 GKAV-ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRK 832
A + T E+ + S + ++ + T P T LAP + +K
Sbjct: 797 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKK 856
Query: 833 GAAPTP-PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 891
T K +A + +S +++ + +AP TS + K P +P
Sbjct: 857 TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 916
Query: 892 A-----------GPAATPAQAQAASTPRKARASESTARSSSSESED----EDVIPATQCL 936
P + A+A +T R + S + +SED E P L
Sbjct: 917 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP-HMLL 975
Query: 937 TPGIRTNVVTMPTAH-PRIAPKASMAGASSSKESSRISDGKKQEGPAT 983
P + VT + PR+ + + S E++ I +GK +G T
Sbjct: 976 RPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETN-ICNGKPVDGLTT 1022
Score = 42.4 bits (98), Expect = 0.003
Identities = 80/454 (17%), Positives = 140/454 (30%), Gaps = 33/454 (7%)
Query: 970 SRISDGKK---QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSA 1026
+ + D KK ++ P + + A L KV S Q T P
Sbjct: 64 AEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP 123
Query: 1027 VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE--EDGE 1084
+ P+ P S + + ++ + + T ++S D ++ + S+ ++ E
Sbjct: 124 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 183
Query: 1085 GPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1144
A ++ L PTP T E P + + P TP +++
Sbjct: 184 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAP 241
Query: 1145 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1204
TPK + + S +P +P T KE A TT PK+
Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 1205 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE----RKKVVDTTKE 1260
A +P P + + K T +E K+ TT +
Sbjct: 302 APTTPK---------------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346
Query: 1261 SSRKGWESRKRKLSGDQPAARTPR----SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKR 1316
+ + +PA TP+ + K+ A + + TT+K A
Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406
Query: 1317 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1376
S K+ + + A P+E T + + PK +
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT---TPKKPAPTTPKEPAPTTPKEPAPTTT 463
Query: 1377 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1410
+K + A T E+ KK T E+
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 497
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 110 bits (276), Expect = 7e-24
Identities = 178/920 (19%), Positives = 303/920 (32%), Gaps = 96/920 (10%)
Query: 201 EDTSSSSDETDVEVKASE-KILQVRAASAPAKGTPGKGATPAPP--------GKAGAVAS 251
++ S D D +V + Q S K T K P P + +
Sbjct: 127 DEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVN 186
Query: 252 QTKAGKPEEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGAASAPAKESPR 306
+ + +E + ++ + S+D +E+T +AK AK TS+V A P E+
Sbjct: 187 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT 246
Query: 307 KGAA---PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 363
KG A P P T P + K + S + +E AP K + P+ A +
Sbjct: 247 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 306
Query: 364 APAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSRSSSEESDSDREALAAMNAAQ 419
+ +P PAP PA + K+ + + +E
Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366
Query: 420 VKPLGKSP---QVKPASTMGMGP---LGKGAGPVPPGKVGPATPSAQV-GKWEEDSESSS 472
K P +PA T P K P P + P TP +E S ++
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426
Query: 473 EESSDSSDGEVPTAV---APAQEKSLGNI-LQAKPTSS--PAKGPPQKAGPVAVQVKAEK 526
+E + ++ PT AP KS + PT++ PA P++ P + A
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486
Query: 527 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT 586
+ + + + PA T + P PKK T K+AP
Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546
Query: 587 QAPR----------KAGTATSPAGSSP----AVAGGTQRPAEDSSSSEESDSEEEKTGLA 632
AP + T T+P +P A A T + ++ E + + ++
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606
Query: 633 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEES 692
A + KG P AP P K P K+ S + ++ +
Sbjct: 607 TPKETAPTTPKGTAPTTLKEP---------APTTPKKPAPKELAPTTTKEPTSTTCDKPA 657
Query: 693 DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 752
+ +P K T + P + +A T+ P K+ +P+ K
Sbjct: 658 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKG 716
Query: 753 PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP 812
P + + P+ K A + P + E + E T K
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT----TPETPPPTTSEVSTPTTTKE 772
Query: 813 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAV 872
H+ +P + +P A PTP + E S + P
Sbjct: 773 PTTIHK-----SPDESTPELSAEPTP------------------KALENSPKEPGVPTTK 809
Query: 873 TSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS---TPRKARASESTARSSSSESEDEDV 929
T A KP + +++ T + A+ T A +E T S + + +
Sbjct: 810 TPA-ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 868
Query: 930 IPATQCLTPGIRTNVVTMPTAHPRIAPKASMA--GASSSKESSRISDGKKQEGPATQVSK 987
TQ TP + T+ T +APK + ++++ ++ + K + AT
Sbjct: 869 STTTQDTTP---FKITTLKTT--TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 923
Query: 988 KNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNK 1047
P T+A K + K + P V + + + T+P +P S +A
Sbjct: 924 TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 983
Query: 1048 LRKPKLPEVQQATKAPESSD 1067
R + P + P+S D
Sbjct: 984 TRPNQTPNSKLVEVNPKSED 1003
Score = 103 bits (256), Expect = 2e-21
Identities = 160/769 (20%), Positives = 266/769 (34%), Gaps = 67/769 (8%)
Query: 76 TRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKT 135
T +P ST+ +E T K+ P + P++ KE A T++ T
Sbjct: 260 TTPKEPASTTP-----KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 136 GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQ 195
P P T K A + +P EP A TT PA +P + +
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 373
Query: 196 ADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA 255
++++ + ++ + A PA TP + A P A +
Sbjct: 374 PAPTTKEPAPTTPKEPAPT----------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 423
Query: 256 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
P+E + ++++ + + +E PA A + K PA +P K AP P
Sbjct: 424 TTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTP-KEPAPTTPK 481
Query: 316 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK-PSGKAPQVRAASAPAKESPR--K 372
K P K A ++ ++ +++ AP K P+ P+ A + P K +P +
Sbjct: 482 KPAPTTPKEPAPTTPKEPAPTT----TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 537
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
AP P K P + E+ ++ E + AA +P +P+ +PA
Sbjct: 538 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK-EPA 596
Query: 433 STMGMGP-----------LGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG 481
T P KG P + P TP K E ++ E +S + D
Sbjct: 597 PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDK 655
Query: 482 EVPT---AVAPAQEKSLGNILQAKPTSSPAKG--PPQKAGPVAVQVKAEKPMDNSESSEE 536
PT AP K +P + KG P P K P + + ++ +
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 715
Query: 537 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV--RVGTQAPRKAGT 594
S S++ PA T + P PKK T P V T K T
Sbjct: 716 GPTSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 774
Query: 595 A--TSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA-----VTVGQAKSVGKGLQV 647
SP S+P ++ P +S +E KT A T + K+ + L+
Sbjct: 775 TIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833
Query: 648 KAASVPVKGSLGQGTA----PVLPGKTGPTVTQVKAEKQEDSESSEEES-DSEEAAASPA 702
+ + + TA K T TQV + +D+ + + + A
Sbjct: 834 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893
Query: 703 QVKTSVKKTQAKANPAAA-----RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNP 757
K ++ T+ P RA ++K T P K A + K P VR P
Sbjct: 894 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 953
Query: 758 QNSTVLARGPASVPSV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 803
+ + + +++P + + Q T P + S E + + E
Sbjct: 954 KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1002
Score = 95.9 bits (237), Expect = 2e-19
Identities = 183/948 (19%), Positives = 324/948 (34%), Gaps = 91/948 (9%)
Query: 65 AEEDAALQAKKTRVSDPISTSESSEEEEEAEAET--AKATPRLASTNSSVLGADLPSSMK 122
++E + K+T V +T+ + + + + +T AK T + T++ L K
Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237
Query: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAF 182
KAET G + P +P EP++ T S P
Sbjct: 238 PTPKAETTTKGPALTTPKEP-------------TPTTPKEPASTTPKEPTPTTIKSAPT- 283
Query: 183 GAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP 242
+P + A ++ ++ + ++ + E AP T K A P
Sbjct: 284 -TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP---TTTKSAPTTP 339
Query: 243 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK 302
A + P+E + ++ +E + + + PA A + K A PA
Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 303 ESPRKGAAPAPPGKTGPAVAKAQA---GKREEDSQSSSEESDSEEEAPAQAK---PSGKA 356
+P K AP P + P K + K + + S + ++E AP K + K
Sbjct: 400 TTP-KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458
Query: 357 PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMN 416
P PA +P K AP P+K P + ++ ++ +
Sbjct: 459 PSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK------------ 505
Query: 417 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 476
KP +P+ +PA T K P P K+ P TP E ++ E
Sbjct: 506 ----KPAPTTPK-EPAPT-----TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 555
Query: 477 DSSDGEVPTAVAPAQEKSLGNILQAKPT-SSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 535
+ E PT P + A T PA P++ P + A + +
Sbjct: 556 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 615
Query: 536 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 595
+ + + PA T + P P T P T A P P K
Sbjct: 616 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPAP 674
Query: 596 TSPAGSSPAVAGGTQRPA--EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVP 653
T+P +P GT E + ++ + + +E A + KG + P
Sbjct: 675 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---------LAPTTTKGPTSTTSDKP 725
Query: 654 VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQA 713
+ + TAP P + PT + A + + + SE + + + T++ K+
Sbjct: 726 AP-TTPKETAPTTPKEPAPTTPKKPA---PTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 781
Query: 714 KANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV 773
++ P + P+ K ++P + ++P+ KP + R + P
Sbjct: 782 ESTPELSAEPTPKALENSPKE----PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 837
Query: 774 GKAV-ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRK 832
A + T E+ + S + ++ + T P T LAP + +K
Sbjct: 838 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKK 897
Query: 833 GAAPTP-PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 891
T K +A + +S +++ + +AP TS + K P +P
Sbjct: 898 TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 957
Query: 892 A-----------GPAATPAQAQAASTPRKARASESTARSSSSESED----EDVIPATQCL 936
P + A+A +T R + S + +SED E P L
Sbjct: 958 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP-HMLL 1016
Query: 937 TPGIRTNVVTMPTAH-PRIAPKASMAGASSSKESSRISDGKKQEGPAT 983
P + VT + PR+ + + S E++ I +GK +G T
Sbjct: 1017 RPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETN-ICNGKPVDGLTT 1063
Score = 42.4 bits (98), Expect = 0.003
Identities = 80/454 (17%), Positives = 140/454 (30%), Gaps = 33/454 (7%)
Query: 970 SRISDGKK---QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSA 1026
+ + D KK ++ P + + A L KV S Q T P
Sbjct: 105 AEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP 164
Query: 1027 VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE--EDGE 1084
+ P+ P S + + ++ + + T ++S D ++ + S+ ++ E
Sbjct: 165 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 224
Query: 1085 GPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1144
A ++ L PTP T E P + + P TP +++
Sbjct: 225 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAP 282
Query: 1145 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1204
TPK + + S +P +P T KE A TT PK+
Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 1205 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE----RKKVVDTTKE 1260
A +P P + + K T +E K+ TT +
Sbjct: 343 APTTPK---------------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387
Query: 1261 SSRKGWESRKRKLSGDQPAARTPR----SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKR 1316
+ + +PA TP+ + K+ A + + TT+K A
Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447
Query: 1317 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1376
S K+ + + A P+E T + + PK +
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT---TPKKPAPTTPKEPAPTTPKEPAPTTT 504
Query: 1377 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1410
+K + A T E+ KK T E+
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 538
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 105 bits (263), Expect = 2e-22
Identities = 266/1277 (20%), Positives = 419/1277 (32%), Gaps = 160/1277 (12%)
Query: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
S + SE S + T A S S ++G S + + TE G++
Sbjct: 1626 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI---SSGSTETTALPGST 1682
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA---AKPGMVSAGQ 195
+ K+ S +SP + P++ T+ E S G+ A PG +
Sbjct: 1683 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 1742
Query: 196 ADSSSEDTSSSSDETDVEVK-ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK 254
S + SS TD + S + S +PG T P T
Sbjct: 1743 VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNT------TA 1796
Query: 255 AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPP 314
+G E + S S +PA G T++ G ++ K PAPP
Sbjct: 1797 SGLLEASTPVHSSTGSPHTTLSPA----------GSTTRQGESTTFQSWPSSKDTMPAPP 1846
Query: 315 GKTGPAVAKAQAGKREEDSQ-------SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK 367
T V + S SS+ SEE + P A +PA+
Sbjct: 1847 TTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA----TTPSPAR 1902
Query: 368 ESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP 427
+ + + P + Q + + SEES + + + P S
Sbjct: 1903 STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT--HTISSPPSTTSA 1960
Query: 428 QVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV 487
V+ ++ P P S G+ EE + S S + + T V
Sbjct: 1961 LVEEPTSYHSSPGSTATTHFPDS-------STTSGRSEESTASHSSQDATG------TIV 2007
Query: 488 APAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAP 547
PA +S ++L + T+SP + + + S + S S + +P
Sbjct: 2008 LPA--RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP 2065
Query: 548 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 607
A+ T++ ++ P T+TTA T P + +T+ + SSP
Sbjct: 2066 ASTTSSGVSEESTTSHSR--PGSTHTTAFPD------STTTPGLSRHSTT-SHSSPGSTD 2116
Query: 608 GTQRPAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 662
T PA ++S S S S T A++ G ++ G + T
Sbjct: 2117 TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE-------------STT 2163
Query: 663 APVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA 722
PG T T+ + + S + +V +S + +PA++ +
Sbjct: 2164 FHSSPGSTHTTLFP-------------DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS 2210
Query: 723 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 782
P +G +A + A+ PS PV + ST R P S P+ A+
Sbjct: 2211 PGLQGESTA-FQTHPASTHTTPSPPSTATAPV---EESTTYHRSPGSTPTTH---FPASS 2263
Query: 783 AQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT 842
+G E S D+ + A SG+ + ++P P T
Sbjct: 2264 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE----ITTLPGSTT 2319
Query: 843 GPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ 902
P ++A + SS S + +PA++TS V + + S + P +T +
Sbjct: 2320 TPGLSEAST---TFYSSPRSPTTTLSPASMTSLGVGE------ESTTSRSQPGSTHSTVS 2370
Query: 903 AASTPRKARASESTA-RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA 961
AST + EST SSS S + V P T T +R T T H R A +
Sbjct: 2371 PASTTTPGLSEESTTVYSSSPGSTETTVFPRTP--TTSVRGEEPT--TFHSRPASTHTTL 2426
Query: 962 GASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSS 1021
S S + G PA+L + +S + S
Sbjct: 2427 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARS 2486
Query: 1022 GVDSAVG---------------TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESS 1066
VG TLP SP + S+ K T P+ P+ + SS
Sbjct: 2487 TTSGLVGESTPSRLSPSSTETTTLPG-SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 2545
Query: 1067 DDSEDSSDSSS--GSEE-----DGEGPQGAKSAHTLVGPTPSRTETLV----EETAAESS 1115
SE+SS S S GS D G T +P T+T + T+ S
Sbjct: 2546 GVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQ 2605
Query: 1116 EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQ 1175
E S ++PG T A S ++T S S +TL PD + +
Sbjct: 2606 ESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF----PDSTTSSGIVE 2661
Query: 1176 AAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQV 1235
A+ + TG +P S P + T ++ T P P + A
Sbjct: 2662 ASTRVHSSTGSPRTT--LSPASSTSPGLQGESTTFQTHPASTHTT------PSPPSTA-- 2711
Query: 1236 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR--TPRSKKKKKLGA 1293
+ V+ T SS S K + P A TP S G
Sbjct: 2712 -TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 2770
Query: 1294 GEGGEASVSPEKTSTTS 1310
GE + +SP T T+
Sbjct: 2771 GESTTSRISPGSTEITT 2787
Score = 98.2 bits (243), Expect = 5e-20
Identities = 266/1333 (19%), Positives = 457/1333 (34%), Gaps = 142/1333 (10%)
Query: 68 DAALQAKKTRVSDPI---STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEK 124
D L T S P +TS SS + T S+ ++ S+
Sbjct: 1033 DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 1092
Query: 125 AKAETEKAGKT-GNSMPHPATG--KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPA 181
T +G ++ H +TG +T + S SP E +A T + T S P+
Sbjct: 1093 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 1152
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPA 241
A + ++ S+ T + T I +S A GT A
Sbjct: 1153 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH---SSPDASGTTPSSAHST 1209
Query: 242 PPGKAGAVASQTKAGKPEEDSESSS------EESSDSEEETPAAKALLQAKASGKTSQVG 295
G+ + S+ G E + S E+S + +P + + AS + VG
Sbjct: 1210 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 1269
Query: 296 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEES----------DSEEE 345
S ++ P + P T ++ S+ S+E + EE
Sbjct: 1270 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP 1329
Query: 346 APAQAKPSGKAPQV----RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 401
++P+ + S +ES +PA + PA +E + S
Sbjct: 1330 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 1389
Query: 402 SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK-----VGPAT 456
S S + + A + + ++ P+ST G P K P +
Sbjct: 1390 SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 1449
Query: 457 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG 516
P A + S SEESS S T + + + L +PT+S + +A
Sbjct: 1450 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT 1509
Query: 517 PVAVQVKAEKPMDNSESSEESSDSADSEEAPA-AMTAAQAKPALKIPQTKACPKKTNTTA 575
A S + S ++ P +T+ + + + T T A
Sbjct: 1510 LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA 1569
Query: 576 SAKVAPVRVGTQA----PRKAGTATSPAGSSPAVAGGT----QRPAED-----SSSSEES 622
S+ A ++ + P + T SP G++ A + RP+ S+SS
Sbjct: 1570 SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL 1629
Query: 623 DSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKGSLGQGTAPVLPGKT------GPTVT 675
EE T + + G + G L ++A+ + G T+P+ G T G T T
Sbjct: 1630 GRSEESTTVHSSPG---ATGTALFPTRSATSVLVGE--PTTSPISSGSTETTALPGSTTT 1684
Query: 676 QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKV 735
+EK SS D+ + AS S + T + + P + + G+ + PG
Sbjct: 1685 AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG-- 1742
Query: 736 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP---SVGKAVATAA----------Q 782
V+ + A SP + +P ++T + GP S S G T +
Sbjct: 1743 VSQESTASHSSPGSTDTTL-SPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLE 1801
Query: 783 AQTGPEEDSGS-----SEEESDSEEEAETLAQVKPSGKTHQ-----IRAALAPAKESPRK 832
A T +GS S S + + T Q PS K +A +
Sbjct: 1802 ASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHG 1861
Query: 833 GAAPTPPGKTGPSAAQAGKQDDSGS--SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRS 890
+ TP S+ G+ ++S + SS + + +PA T++ +++ +
Sbjct: 1862 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAY------ 1915
Query: 891 PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 950
++P Q P + AS + S +S S I + P + +V PT+
Sbjct: 1916 ----HSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP----PSTTSALVEEPTS 1967
Query: 951 HPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEA 1010
+ +P ++ A++ S + G+ +E A+ S+ ++ L + + S
Sbjct: 1968 Y-HSSPGST---ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 2023
Query: 1011 QPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSE 1070
P + + ++ + + T P S +ST+ + P+ P + + SS SE
Sbjct: 2024 SPISSGSMETTALPGST-TTPGLSEKSTTFHSS-------PRSPATTLSPASTTSSGVSE 2075
Query: 1071 DSSDSSS--GSEE-----DGEGPQGAKSAHTLVGPTPSRTETLV----EETAAESSEDDV 1119
+S+ S S GS D G T +P T+T + T+ S E
Sbjct: 2076 ESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTT 2135
Query: 1120 VAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGM 1179
S ++PG T A S ++T S S +TL PD + +A+
Sbjct: 2136 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF----PDSTTSSGIVEASTR 2191
Query: 1180 LSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASV 1239
+ TG +P S P + T ++ T P P + A +
Sbjct: 2192 VHSSTGSPRTT--LSPASSTSPGLQGESTAFQTHPASTHTT------PSPPSTA---TAP 2240
Query: 1240 VKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR--TPRSKKKKKLGAGEGG 1297
V+ T SS S K + P A TP S G GE
Sbjct: 2241 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 2300
Query: 1298 EASVSPEKTSTTS 1310
+ +SP T T+
Sbjct: 2301 TSRISPGSTEITT 2313
Score = 95.1 bits (235), Expect = 4e-19
Identities = 269/1330 (20%), Positives = 445/1330 (33%), Gaps = 176/1330 (13%)
Query: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL- 113
+T+ G K+ + ++ P ST+ +E + + ST++++
Sbjct: 298 RTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG-----STDTTLSP 352
Query: 114 GADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLV--S 171
G PSS+ ++ G T + T T + LL +P S+ S +TTL S
Sbjct: 353 GTTTPSSLGPESTTFHSSPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPSS 410
Query: 172 ETEEEGSVPAFGA--------AAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQV 223
T EG F + A G SA S++ +S SS T AS L
Sbjct: 411 STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPT-THFSASSTTLGH 469
Query: 224 RAASAPAKGTPGKGATPAPPGK---AGAVASQTKAGKPEEDSES-----SSEESSDSEEE 275
S P +P AT PP + +G V T + +++ SS S SEE
Sbjct: 470 SEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEES 529
Query: 276 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 335
+ K+S T AA A G+ + + +G+ EE S
Sbjct: 530 ATFHGSTTHTKSS--TPSTTAALAHTSYHSSLGSTETTHFRDSSTI----SGRSEESKAS 583
Query: 336 SSEESDSEEEAPAQAKPSGKAPQVRAA-SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 394
S S + P+G P V S P+ S A P T + G
Sbjct: 584 HS----SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST------TKPGLS 633
Query: 395 EEDSRSSSEESDSDREAL-AAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP------- 446
E+ + S D L A+M ++ V + +P ST G P
Sbjct: 634 EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQEST 693
Query: 447 VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS 506
GP + G S + S G T + P + G + + P S
Sbjct: 694 ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHS 753
Query: 507 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 566
+ P P + S + S D+ AP T+A +P+ + +
Sbjct: 754 STRSPHTTLSPAGSTTR----QGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPS 809
Query: 567 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEE 626
T+ +A + + + ++ T S GS+ + P D++S +S
Sbjct: 810 SIPTTHISARSTTSGL------VEESTTYHSSPGSTQTM----HFPESDTTSGRGEESTT 859
Query: 627 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT---VTQVKAEKQE 683
+ T+ A S L + S PG T T + + + E
Sbjct: 860 SHSSTTHTISSAPSTTSALVEEPTSYHSS-----------PGSTATTHFPDSSTTSGRSE 908
Query: 684 DSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAK 743
+S +S D+ PA+ TSV ++ +P ++ + T + PG T
Sbjct: 909 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS---GSMETTALPGSTTTPG--LS 963
Query: 744 QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEE 803
+RS + P R+P +T L+ PAS S G + EE + S +
Sbjct: 964 ERSTTFHSSP-RSP--ATTLS--PASTTSSGVS-----------EESTTSRSRPGSTHTT 1007
Query: 804 AETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESD 863
A + P H + +P S P +GPS ++ + SS S
Sbjct: 1008 AFPDSTTTPGLSRHSTTSHSSPG--STDTTLLPASTTTSGPS-----QESTTSHSSSGST 1060
Query: 864 SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE 923
+P + T+ + F + P +T ST ST SS+
Sbjct: 1061 DTALSPGSTTALSFGQESTTF------HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 1114
Query: 924 SEDEDVIPATQCLTPGIRTNVVTMPT--AHPRIAPKASMAGASSSKESSRISDGKKQEGP 981
S + PA+ +PG++ T A P + +ES+
Sbjct: 1115 SPRTTLSPASS-TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST----------- 1162
Query: 982 ATQVSKKNPASLPLTQAALKVLAQKASE------AQPPVARTQPSSGVDSAVGTLPATSP 1035
++P S P T SE + P + T PSS + G +T+
Sbjct: 1163 ---TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 1219
Query: 1036 QSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAK----- 1090
+ + + T P + +A+ SS S ++ S + G G +
Sbjct: 1220 RISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 1279
Query: 1091 -SAHTLVGPTPSRTETLVEE-----TAAESSEDDVVAPSQSLLSGYMTPGLT----PANS 1140
S H+ V P + T L EE +++ S + V P + S + T PA++
Sbjct: 1280 GSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 1339
Query: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAA----GMLSPKTGGKEAASGTTPQ 1196
+ T +S + A P Q P G S ++GT
Sbjct: 1340 HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLS 1399
Query: 1197 KSRKPKKG-AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVV 1255
+R G G S L+ S T L G P S+ + T R
Sbjct: 1400 PARSTTSGLVGESTPSRLSPSSTETTTLPGSP-------TTPSLSEKSTTFYTSPRSPDA 1452
Query: 1256 DTTKESSRKGWESRKRKLSGDQPAA-----------RTPRSKKKKKLGAGEGG-EASVSP 1303
+ ++ S + S QP + + S++ + +G EA++SP
Sbjct: 1453 TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSP 1512
Query: 1304 EKTSTTSKGK 1313
T+ +S G+
Sbjct: 1513 GSTTASSLGQ 1522
Score = 91.3 bits (225), Expect = 6e-18
Identities = 254/1250 (20%), Positives = 409/1250 (32%), Gaps = 230/1250 (18%)
Query: 81 PISTSESSEEEEEAEAETAKATPRLASTNSSVL-GADLPSSMKEKAKAETEKAGKTGNSM 139
P ST+ S EE + + R ST+++ G+ + +++ A G T ++
Sbjct: 1707 PASTTSSGVSEESTTSHS-----RPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTL 1761
Query: 140 PHPATGKTVANLLSGKSPRKSAEP-SANTTLVSETEE-----EGSVPAFGAAAKPG--MV 191
+ G T A+ L +S + P S TTL+ + E S P + P +
Sbjct: 1762 ---SPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 1818
Query: 192 SAGQADSSSEDTS-----SSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKA 246
AG E T+ SS D + +++ S + G+P T
Sbjct: 1819 PAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVEL---STTSHGSPSSTPT------T 1869
Query: 247 GAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR 306
AS T G+ EE S + +P A A + A TS + S SP
Sbjct: 1870 HFSASSTTLGRSEE---------STTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPG 1920
Query: 307 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA 366
P + +G+ EE S S + + P+ SA
Sbjct: 1921 STQTMHFPESS------TASGRSEESRTSHSSTTHTISSPPS------------TTSALV 1962
Query: 367 KESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKS 426
+E ++P T + G+ EE + S S + + L A + V LG+S
Sbjct: 1963 EEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL-LGES 2021
Query: 427 PQVKPASTMGMGPLGKGAGPVPPG--------KVGPATPSAQVGKWEEDSESSSEES--S 476
P S+ M PG P +P+ + S SEES S
Sbjct: 2022 T-TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 2080
Query: 477 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 536
S G T P + G L T+S + + P S +S
Sbjct: 2081 HSRPGSTHTTAFPDSTTTPG--LSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 2138
Query: 537 SSDSADSEEAPAAMTAAQ-----------------------------AKPALKIPQTKAC 567
S S D+ +P + TA + + ++ +
Sbjct: 2139 SPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 2198
Query: 568 PKKTNTTASAKVAPVRVGTQA--PRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSE 625
P+ T + AS+ ++ + A A T T+P+ S A A P E+S++ S
Sbjct: 2199 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATA-----PVEESTTYHRSPGS 2253
Query: 626 EEKTGLAV-----------TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKT---- 670
T T+ + G +A G T+ + PG T
Sbjct: 2254 TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 2313
Query: 671 --GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
G T T +E SS + + AS + + T +++ P + + + +
Sbjct: 2314 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS 2373
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
+ PG + + SP + V P+ T RG + +T T
Sbjct: 2374 TTTPG-LSEESTTVYSSSPGSTETTVF-PRTPTTSVRGEEPTTFHSRPASTHTTLFTEDS 2431
Query: 789 EDSGSSEEES--------------------DSEEEAETLAQVKPS---------GKTHQI 819
SG +EE + D EE+ T S T +
Sbjct: 2432 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2491
Query: 820 RAALAPAKESPRKGAAPTPPGK--------------TGPSAAQA----GKQDDSGSSSEE 861
P++ SP T PG T P + A SG S E
Sbjct: 2492 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 2551
Query: 862 SDSDGEAPAAVTSA--QVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 919
S S + + T+A P + S + P +T AST + EST
Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2611
Query: 920 SSSESEDEDVIP-ATQCLTPGIRTNVV------TMPTAHPRIAPKASMAGASSSKESSRI 972
SS S D + P +T L+ G + T T P + + AS+ SS
Sbjct: 2612 SSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2671
Query: 973 SDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA 1032
S P T +S + S L + + +T P+S T P+
Sbjct: 2672 S-------PRTTLSPASSTSPGL-------------QGESTTFQTHPAS-----THTTPS 2706
Query: 1033 TSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA 1092
+T+ + T R P + +S SE S+ S + G P A S
Sbjct: 2707 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 2766
Query: 1093 HTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS--QASKATPKLD 1150
T R E+ + S+E + S + TPGL+ A++ +S +P
Sbjct: 2767 ------TSGRGESTTSRISPGSTEITTLPGSTT------TPGLSEASTTFYSSPRSPTTT 2814
Query: 1151 SSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1200
SP+ ++L ++ ++P +SP AS TTP S +
Sbjct: 2815 LSPASMTSLGVGEE-STTSRSQPGSTHSTVSP-------ASTTTPGLSEE 2856
Score = 91.3 bits (225), Expect = 6e-18
Identities = 265/1306 (20%), Positives = 448/1306 (34%), Gaps = 162/1306 (12%)
Query: 81 PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMP 140
P ST+ S E ++ +PR T S + P E +T
Sbjct: 2651 PDSTTSSGIVEASTRVHSSTGSPR---TTLSPASSTSPGLQGESTTFQT----------- 2696
Query: 141 HPATGKTVANLLSGKSPRKSAEPSANTTLVSET----EEEGSVPAFGAAAKPGMVSAGQA 196
HPA+ T + PS T V E+ GS P A ++G +
Sbjct: 2697 HPASTHTTPS-----------PPSTATAPVEESTTYHRSPGSTPTTHFPASS--TTSGHS 2743
Query: 197 DSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAG 256
+ S+ SS D + ++ R S ++ +PG PG S T G
Sbjct: 2744 EKSTI-FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG------STTTPG 2796
Query: 257 KPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK 316
E + S S + +PA+ L TS+ S + SP P +
Sbjct: 2797 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL-SE 2855
Query: 317 TGPAVAKAQAGKREED--SQSSSEESDSEEEAPAQAKPSGKAPQV----RAASAPAKESP 370
V + G E +S++ EE ++P+ + S +ES
Sbjct: 2856 ESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 2915
Query: 371 RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP--Q 428
+PA + PA + E+S + S S L+ + +G+S +
Sbjct: 2916 AFPGSPASTQTGLPAT--LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSR 2973
Query: 429 VKPASTMGMGPLGKGAGPVPPGK-----VGPATPSAQVGKWEEDSESSSEESSDSSDGEV 483
+ P+ST G P K P +P A + S SEESS S
Sbjct: 2974 LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG 3033
Query: 484 PTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADS 543
T + + + L +PT+S + +A A S + S ++
Sbjct: 3034 STHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTET 3093
Query: 544 EEAPA-AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA----PRKAGTATSP 598
P +T+ + + + T T AS+ A ++ + P + T SP
Sbjct: 3094 TLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 3153
Query: 599 AGSSPAVAGGT----QRPAED-----SSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVK 648
G++ A + RP+ S+SS EE T + + G + G L +
Sbjct: 3154 PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPG---ATGTALFPTR 3210
Query: 649 AASVPVKGSLGQGTAPVLPGKT------GPTVTQVKAEKQEDSESSEEESDSEEAAASPA 702
+A+ + G T+P+ G T G T T +EK SS D+ + AS
Sbjct: 3211 SATSVLVGE--PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT 3268
Query: 703 QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV 762
S + T + + P + + G+ + PG V+ + A SP + +P ++T
Sbjct: 3269 SSGVSEESTTSHSRPGSTHTTAFPGSTTMPG--VSQESTASHSSPGSTDTTL-SPGSTTA 3325
Query: 763 LARGPASVPSVGKAVATAA-------------QAQTGPEEDSGS-----SEEESDSEEEA 804
+ GP S +T +A T +GS S S + +
Sbjct: 3326 SSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGE 3385
Query: 805 ETLAQVKPSGKTHQ-----IRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS-- 857
T Q P+ K +A + + TP S+ G+ ++S +
Sbjct: 3386 STTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVH 3445
Query: 858 SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTA 917
SS + + +PA T++ +++ + + P +T S R EST
Sbjct: 3446 SSPVATATTPSPARSTTSGLVEESTTY------HSSPGSTQTMHFPESDTTSGRGEESTT 3499
Query: 918 RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKK 977
SS+ T P + +V PT++ +P ++ A++ S + G+
Sbjct: 3500 SHSSTTH--------TISSAPSTTSALVEEPTSY-HSSPGST---ATTHFPDSSTTSGRS 3547
Query: 978 QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQS 1037
+E A+ S+ ++ L + + S P + + ++ + + T P S +S
Sbjct: 3548 EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGLSEKS 3606
Query: 1038 TSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS--GSEE-----DGEGPQGAK 1090
T+ + P+ P + + SS SE+S+ S S GS D G
Sbjct: 3607 TTFHSS-------PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS 3659
Query: 1091 SAHTLVGPTPSRTETLV----EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKAT 1146
T +P T+T + T+ S E S ++PG T A S ++T
Sbjct: 3660 RHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQEST 3719
Query: 1147 PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAG 1206
S S +TL PD + +A+ + TG +P S P
Sbjct: 3720 TFHSSPGSTHTTLF----PDSTTSSGIVEASTRVHSSTGSPRTT--LSPASSTSPGLQGE 3773
Query: 1207 NPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGW 1266
+ T ++ T P P + A + V+ T SS
Sbjct: 3774 STAFQTHPASTHTT------PSPPSTA---TAPVEESTTYHRSPGSTPTTHFPASSTTSG 3824
Query: 1267 ESRKRKLSGDQPAAR--TPRSKKKKKLGAGEGGEASVSPEKTSTTS 1310
S K + P A TP S G GE + +SP T T+
Sbjct: 3825 HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 3870
Score = 90.9 bits (224), Expect = 8e-18
Identities = 227/1153 (19%), Positives = 387/1153 (33%), Gaps = 171/1153 (14%)
Query: 81 PISTSESSEEEEE----AEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTG 136
P S++ S E+ + + + TP A + +S G S + + T G T
Sbjct: 3817 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 3876
Query: 137 NSMPHPATGKTVANLLSG-KSPRKSAEPSANTTL----VSETEEEGSVPAFGAAAKPGMV 191
P + S +SP + P++ T+L S T +
Sbjct: 3877 T----PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 3932
Query: 192 SAGQADSSSEDTSSSSDETDVEVKASEKILQVRAA------SAPA--------KGTPGKG 237
+ G ++ S+ SSS T+ V VR S PA + + G
Sbjct: 3933 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSG 3992
Query: 238 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 297
T G+ AS T+ G P + + E S + + + + A TS +
Sbjct: 3993 LTEESTAFPGSPAS-TQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGE 4051
Query: 298 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 357
S P++ SP PG + S SE+S + +P ++ + +P
Sbjct: 4052 STPSRLSPSSTETTTLPGSP--------------TTPSLSEKSTTFYTSP-RSPDATLSP 4096
Query: 358 QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 417
+S ++ES + P T + G +E + S S + + EA + +
Sbjct: 4097 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGST--EATLSPGS 4154
Query: 418 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSD 477
LG+ +S + G V +TP+
Sbjct: 4155 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT------------------H 4196
Query: 478 SSDGEVPTAVAPAQEKSLG-----NILQAKPTSSPAKGPPQKAGPVAVQVKA---EKPMD 529
SS G + T + PA S G Q+ P+SS P V V+V +P
Sbjct: 4197 SSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSS 4256
Query: 530 NSES--SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQ 587
+ S S+ SEE+ ++ A P A + +P+ G+
Sbjct: 4257 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT---SVLVGEPTTSPISSGST 4313
Query: 588 APRKAGTATSPAG---------SSPAVAGGTQRPAEDSSS--SEESDSEEEKTGLAVTVG 636
+T+ AG SSP T PA +SS SEES + + G T
Sbjct: 4314 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTA 4373
Query: 637 QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEE 696
S V S S G + PG T + ++ S S E + +
Sbjct: 4374 FPSSTTMP-GVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPD 4432
Query: 697 AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN 756
+ ++ S + +P +P+ T + +K +P+
Sbjct: 4433 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 4492
Query: 757 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKT 816
+ ST P+S P+ + ++ ++ EES + + PS
Sbjct: 4493 VELSTTSHGSPSSTPTTHFSASSTTLGRS----------EESTTVHSSPVATATTPS--- 4539
Query: 817 HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSS---EESDSDGEAPAAVT 873
PA+ + + + P + Q +S ++S EES + +
Sbjct: 4540 --------PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTI 4591
Query: 874 SAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA- 932
S+ + +P + P +T S+ R+ ESTA SS ++ V+PA
Sbjct: 4592 SSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPAR 4651
Query: 933 --TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNP 990
T L T+ ++ + P ++ S K ++ S +P
Sbjct: 4652 STTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS---------------SP 4696
Query: 991 ASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSA-VGTLPATSPQSTSVQAKGTNKLR 1049
+S P T S + + R++ S+ V S+ V T SP ++
Sbjct: 4697 SSTPTTH---------FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTA 4747
Query: 1050 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE 1109
P Q PESS S S +S + + + HT+ P PS T LVEE
Sbjct: 4748 YHSSPGSTQTMHFPESSTASGRSEESRTSH---------SSTTHTISSP-PSTTSALVEE 4797
Query: 1110 TAAESSEDDVVA----PSQSLLSGYM-----------TPGLTP------ANSQASKATPK 1148
+ S +A P S SG T G+TP + + +++T
Sbjct: 4798 PTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTF 4857
Query: 1149 LDSSPSVSSTLAA 1161
S S+ +TLA+
Sbjct: 4858 YISPGSMETTLAS 4870
Score = 88.6 bits (218), Expect = 4e-17
Identities = 212/1067 (19%), Positives = 359/1067 (33%), Gaps = 161/1067 (15%)
Query: 251 SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG-- 308
S T +G EE + S S + P+ A KTS + +AS P
Sbjct: 214 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 273
Query: 309 -----------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA--PAQAKPSGK 355
++P P +T +G E+ + S S + A + P
Sbjct: 274 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 333
Query: 356 APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGK--------QEEDSRSSSEESDS 407
+ S P P GP + + + S E+ +
Sbjct: 334 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 393
Query: 408 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED 467
+ + P + +T P K P P G T SA V
Sbjct: 394 PVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSG-----TTSAFV------ 442
Query: 468 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSP---AKGPPQKAGPVAVQVK 523
S++ SS SS PT A +LG+ ++ P SSP A PP + V+
Sbjct: 443 KLSTTYHSSPSS---TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVE 499
Query: 524 AEKPMDNSESS-------EESSDSADSEEAPA-------------AMTAAQAKPAL--KI 561
S S E S+ S SEE+ + TAA A + +
Sbjct: 500 ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL 559
Query: 562 PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE 621
T+ + ++T S + + +P T PAGS+P+V G P+ SS S E
Sbjct: 560 GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSME 619
Query: 622 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 681
+ T + GL K+ + ++P P T + +
Sbjct: 620 T-----------TALPGSTTKPGLSEKSTTF--------YSSPRSPDTTHLPASMTSSGV 660
Query: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
E+S +S S A P ++ ++ + A+ +P T +PG TA++
Sbjct: 661 SEESTTSHSRPGSTHTTAFPG---STTMPGLSQESTASHSSPGPTDTTLSPGS-TTASSL 716
Query: 742 AKQRSPSKVKPPVRN----PQNSTVLARGPASVP----------SVGKAVATAAQAQTGP 787
+ + +P P N+T AS+P ++ A +T Q ++
Sbjct: 717 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGES-T 775
Query: 788 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT----G 843
S S +++ T A V+PS +H +++ S R + T
Sbjct: 776 TFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS 835
Query: 844 PSAAQA---GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900
P + Q + D + EES + + S+ + +P + P +T
Sbjct: 836 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 895
Query: 901 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM 960
S+ R+ ESTA SS ++ V+PA + ++ +P +S
Sbjct: 896 HFPDSSTTSGRSEESTASHSSQDATGTIVLPA---------RSTTSVLLGESTTSPISSG 946
Query: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1020
+ +++ S + G + S ++PA+ T + + SE + +R++P
Sbjct: 947 SMETTALPGSTTTPGLSERSTTFHSSPRSPAT---TLSPASTTSSGVSE-ESTTSRSRPG 1002
Query: 1021 SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDS-----SDS 1075
S T P ST+ + P T P S+ S S S S
Sbjct: 1003 S-------THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 1055
Query: 1076 SSGSEEDGEGP----------------QGAKSAHTLVGPTPSRTETLVEET----AAESS 1115
SSGS + P S HT + P + + +VE + ++ S
Sbjct: 1056 SSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 1115
Query: 1116 EDDVVAPSQSL---LSGYMTPGLT-PANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1171
++P+ S L G T T PA++ + + P ++P ST +
Sbjct: 1116 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 1175
Query: 1172 KPQQA--AGMLSPKT--GGKEAASGTTPQKSRKPKKGAGNPQASTLA 1214
P + +G T ASGTTP + G G S ++
Sbjct: 1176 FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 1222
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 105 bits (263), Expect = 2e-22
Identities = 254/1420 (17%), Positives = 474/1420 (33%), Gaps = 189/1420 (13%)
Query: 74 KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGAD-------LPSSMKEKAK 126
+++R P+ S + TP + S A P+ +++
Sbjct: 623 RRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSR 682
Query: 127 AETE-KAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
+ T + G++ + P ++ + + G+S ++ + + SE + + +
Sbjct: 683 SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR 742
Query: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGK 245
+ SS S SS + KA ++ R+ S + K TP +
Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRS----KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSR 798
Query: 246 AGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESP 305
+G+ + K+ P S SSS + +TP S+ +S+
Sbjct: 799 SGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP--------------SRQSHSSSSPHPKV 844
Query: 306 RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP 365
+ G P T P + + SS + + + P++ SG +P +S P
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP 904
Query: 366 AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK 425
++SP + ++P P K + +Q S SSS + V P
Sbjct: 905 PRQSPSRSSSPQPKVKA------IISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
Query: 426 SPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPT 485
+ + P KV P TP Q S S S + P
Sbjct: 959 ------VESRLLPRYSHSGSSSPDTKVKPETPPRQ-------SHSGSISPYPKVKAQTPP 1005
Query: 486 AVAPA-------QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 538
+ + QEKS +++Q+ P S + + P + S+ S
Sbjct: 1006 GPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP 1065
Query: 539 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGT-ATS 597
D +P + P+L+ +++ PK + +S+ V + + + G + S
Sbjct: 1066 DHRSDTSSPEVRQSHSESPSLQ-SKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
Query: 598 P---AGSSPA----VAGGTQRPAEDSSS---SEESDSEEEKTGLAV------TVGQAKSV 641
P +G SP + + P DS+S ++ E K +A+ T +
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK 1184
Query: 642 GKGLQVKAASVPVKGSLGQGTAPVLP------GKTGPTVTQVKA--EKQEDSESSEEESD 693
K P + + T P G + T Q A +D E E
Sbjct: 1185 DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEK 1244
Query: 694 SEEAAASPAQVKTSVKKTQAKAN----PAAARAPSAKGTISAPGKVVTAAAQAKQRSPSK 749
SEE A +S K + +N P P+ T+ + A S
Sbjct: 1245 SEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASS 1304
Query: 750 VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG-SSEEESDSEEEAETLA 808
P +P++ L+ P S G + G E ++G SSE + D
Sbjct: 1305 WGGPHFSPEHKE-LSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQL 1363
Query: 809 QVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEA 868
+ PS L ++S R SG SS E D
Sbjct: 1364 ETDPS---------LDMKEQSTR----------------------SSGHSSSELSPDAVE 1392
Query: 869 PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDED 928
A ++S Q I P++ P R+P+ ++ A + S + SS D
Sbjct: 1393 KAGMSSNQSISSPVLDAVP-RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGS 1451
Query: 929 VIPATQCL---TPGIRTNVVT------------MPTAHPRIAPKASMAGASSSKESSRIS 973
P+ L +PG++ T P A P+ S + +S + ++
Sbjct: 1452 GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLT 1511
Query: 974 DGKKQEGPATQVSKKNPASLPLTQAALKVLAQK--ASEAQPPVARTQPSSGVDSAVGT-- 1029
+++ G + V +K A PL Q + +Q+ + P R++ S DS T
Sbjct: 1512 PQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRT 1571
Query: 1030 ------LPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSD--------- 1074
+SP+ S + R PEV+ +A + DSS
Sbjct: 1572 PLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA 1631
Query: 1075 ----SSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGY 1130
S SGS G GP S+ T P + S E
Sbjct: 1632 LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEP------------- 1678
Query: 1131 MTPGLTPANSQASKATPKLDSSPSVS-STLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEA 1189
T TP ++S+++P+L +S + +A P+ + P+ SP E
Sbjct: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR---SPSVSSPEP 1735
Query: 1190 ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQ 1249
A +S + ++ A +P+ T + + +P L ++ ++ K T
Sbjct: 1736 AE---KSRSSRRRRSASSPRTKTTSRRGRSPS---PKPRGLQRSRSRSRREKTRTTRRRD 1789
Query: 1250 ERKKVVDTTKESSRKGWESR--KRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTS 1307
T++ R SR +R+ G +R+P ++ + + S +T
Sbjct: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS----RTP 1845
Query: 1308 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKK 1367
TS+ +++ + K + + S + + + S +S+
Sbjct: 1846 PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTS 1905
Query: 1368 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1407
+ +R + + +++++ S +P +++ + +T
Sbjct: 1906 VTRRRSRSRASPVSRRRSR------SRTPPVTRRRSRSRT 1939
Score = 103 bits (256), Expect = 2e-21
Identities = 253/1414 (17%), Positives = 516/1414 (36%), Gaps = 159/1414 (11%)
Query: 72 QAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
Q KK + D SESS E + + K R S + S + K K K++ +K
Sbjct: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR--SESESKKRKHRSPTPKSKRKSKDKK 244
Query: 132 AGKTGNSMPHP--------ATGKTVANLLSGKSPRKSAEPSANTTLV--------SETEE 175
++ ++ P P + + ++ + +S +SA +TT + S
Sbjct: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPG 235
EG P ++PG S + SS +T++ + E K +K + ++A+ P+
Sbjct: 305 EGDAP----FSEPGTTSTQR--PSSPETATKQPSSPYEDKDKDK--KEKSATRPSPSPER 356
Query: 236 KGATPAPPGKAGAVA---------------SQTKAGKPEEDSESSSEESSDSEEETPAAK 280
P PP +A SQ P E S + S E+ P +
Sbjct: 357 SSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSS 416
Query: 281 ALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEES 340
+ + S + ++V ++ + ESP+ PAP + ++ + K ++ ++S
Sbjct: 417 SSESSPPSPQPTKVSRHASSSPESPK----PAPAPGSHREISSSPTSKNRSHGRAKRDKS 472
Query: 341 DSEEEAPAQAKPSGKAPQVRAAS---APAKESPRKGAAP-----APPRKTGPAAAQVQVG 392
S + + A R S P K + +P ++ G + + + G
Sbjct: 473 HSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRG 532
Query: 393 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 452
+ R S + + + +A + + +SP + S + P G+
Sbjct: 533 RSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS--------RSRTPARRGRS 584
Query: 453 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 512
TP+ + + + S + + G + PA+ +S S ++ P
Sbjct: 585 RSRTPARRRSRSRTPTRRRSRSRTPARRGR-SRSRTPARRRS--RTRSPVRRRSRSRSPA 641
Query: 513 QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 572
+++G + A + S + S A + + PA + P++
Sbjct: 642 RRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGR 701
Query: 573 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 632
+ + + V R ++ P++ G + S + + + S S+S E
Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGS--------SSERKNKSRTSQRRSRSNSSPEMKKSR 753
Query: 633 VTVGQAKSVGKGLQVKAASVPVKGSL-GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 691
++ +++S+ + + ++ SL G P +T P ++ Q ++S
Sbjct: 754 ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSR-SGSSQPKAKSRTPP 812
Query: 692 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK-GTISAPGKVVTAAAQAKQRSPSKV 750
S +++ P + K+ K +++ +++ P K GT G + + A + +P +
Sbjct: 813 RRSRSSSSPPPKQKS--KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR- 869
Query: 751 KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV 810
+ + + + +R P+ G + ++ T P + S S + + A +
Sbjct: 870 RSCFESSPDPELKSRTPSRHSCSGSS-PPRVKSSTPPRQSPSRS-----SSPQPKVKAII 923
Query: 811 KPSGKTHQIRAALAP----AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG 866
P ++H ++ +P ++ +PR+ + +P + + SGSSS ++
Sbjct: 924 SPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV--ESRLLPRYSHSGSSSPDTKVKP 981
Query: 867 EAPAAVTSAQVIKP-PLIFVDPNRSPAGPAATPAQAQAASTPRKARASEST--------- 916
E P + + I P P + ++P GP+ + +++ K +S
Sbjct: 982 ETPPRQSHSGSISPYPKV---KAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAG 1038
Query: 917 ARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGK 976
+SS+ E + + Q + T+ P + S + + SK + G+
Sbjct: 1039 VKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGR 1098
Query: 977 -KQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSP 1035
+ P T+++ ++P + + S P +R Q S S+ T+ + S
Sbjct: 1099 SRSSSPVTELASRSP--IRQDRGEFSASPMLKSGMSPEQSRFQSDS---SSYPTVDSNSL 1153
Query: 1036 QSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDS------EDSSDSS---------SGSE 1080
S +K K LP + AT +P D +D +SS E
Sbjct: 1154 LGQSRLETAESK-EKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRE 1212
Query: 1081 EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1140
G G PT S+ E L+E E SE+ P+ +LS +++ L ++
Sbjct: 1213 RSGAGSSPETKEQNSALPTSSQDEELME--VVEKSEE----PAGQILS-HLSSELKEMST 1265
Query: 1141 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAK-PQQAAGMLSPKTGGKEAASGTTPQKSR 1199
+++P+++ P+VS TL + + P A+ P + +P +
Sbjct: 1266 SNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLREN 1325
Query: 1200 ---KPKKGAGNPQAST---LALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKK 1253
P + + T S + + L G P+ LN+ + S+ ++ EQ +
Sbjct: 1326 SFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNG-PF-LNQLETDPSL-----DMKEQSTRS 1378
Query: 1254 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1313
++ E S E K +S +Q + +P + + E ++ SPE +
Sbjct: 1379 SGHSSSELSPDAVE--KAGMSSNQ-SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435
Query: 1314 AKRDKASGDVKEKKGKG-------SLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEK 1366
++R ++ + G G S S G KD P G E PK+ +
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR---TPSRGRSECDSSPEPKALPQT 1492
Query: 1367 KKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKK 1400
+ R + K + SES +K
Sbjct: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSVDQK 1526
Score = 98.6 bits (244), Expect = 4e-20
Identities = 256/1386 (18%), Positives = 475/1386 (34%), Gaps = 200/1386 (14%)
Query: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
S E +A +T + PR S +S L + +E++ +E+ KT P +
Sbjct: 1482 SSPEPKALPQTPR--PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR- 1538
Query: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS 207
SG S +PSA+ E E S P A + + ++ SS E S S
Sbjct: 1539 -----SGSSQELDVKPSASP---QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
Query: 208 DETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 267
S ++ + +AP + G ++P P A + S
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAP-RAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSP 1649
Query: 268 ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAG 327
E S S E +P + +T++ G+ S+P ++ + ++ P + +
Sbjct: 1650 EGSSSTESSP------EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 328 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQV----------RAASAP-AKESPRKGAAP 376
R S SSS E+ S + PS +P+ R+AS+P K + R+G +P
Sbjct: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP 1763
Query: 377 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE---ALAAMNAAQVKPLGKSPQVKPAS 433
+P + G Q SRS E++ + R + ++ + ++ + +S
Sbjct: 1764 SPKPR----------GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813
Query: 434 TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVP-----TAVA 488
G G G P + + S++ + + +S + S S P + +
Sbjct: 1814 RRG----GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS 1869
Query: 489 PA-QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAP 547
PA +S S ++ P + + S +S S + S P
Sbjct: 1870 PATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPP 1929
Query: 548 AAMTAAQAK-PALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVA 606
++++ P + P T + ++ PV R++ + TSP
Sbjct: 1930 VTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV-----TRRRSRSRTSPI------- 1977
Query: 607 GGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL---QVKAASVPVKGSLGQGTA 663
T+R + +S +T VT +++S + + ++ + P +
Sbjct: 1978 --TRRRSRSRTSPVTRRRSRSRTS-PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRT 2034
Query: 664 PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP 723
P+LP K + + + ++ S + +T+ K +P A R
Sbjct: 2035 PLLPRKRSRSRSPLAIRRRSRSRTP----------------RTARGKRSLTRSPPAIRRR 2078
Query: 724 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 783
SA G+ S + T A + S S+ P N + +R P+ P+
Sbjct: 2079 SASGSSSDRSRSATPPA-TRNHSGSRTPPVALNSSRMSCFSR-PSMSPT----------- 2125
Query: 784 QTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTG 843
+ + ++P G + + L A S G P P
Sbjct: 2126 ----------------PLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP---- 2165
Query: 844 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQV--IKPPLIFVDPNRSPAGPAATPAQA 901
D +S E+ + A+T+ + +PP P+ S AG AA +Q
Sbjct: 2166 ---------DHQRTSVPENHAQSRIALALTAISLGTARPP-----PSMSAAGLAARMSQV 2211
Query: 902 QAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA 961
A R + + +S + + TP I T V + P A ++A
Sbjct: 2212 PAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271
Query: 962 GASSSKESSRIS--DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1019
++ S ++ D + PA ++ T AAL L+ S P A
Sbjct: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGAR------TPAALAALSLTGSGTPPTAANYPS 2325
Query: 1020 SSGVDSAVGTLPATSPQSTSVQAK----GTNKLRKPKLPEVQQATKAPESSDDSEDSSDS 1075
SS A + P+S A G+ + A AP S + S
Sbjct: 2326 SSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRV 2385
Query: 1076 SSGSEEDGEG---PQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMT 1132
+ E G P A + P+ + E A S APSQSLL
Sbjct: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445
Query: 1133 PGLTPANSQAS--------KATPKLDS----SPSVSSTLAAKDDPDGKQEAK----PQQA 1176
+P S S + TP S S +V++T ++ D +G P
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505
Query: 1177 AGMLSPKTGGKE--AASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQ 1234
G TG ++ A + P K R+ + + +S+ + S+ + + +
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS---SSSD 2562
Query: 1235 VQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAG 1294
+ S + V E+ + KE+ R+G +P TP +K++ +
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREG-----------RPPEPTPAKRKRRSSSSS 2611
Query: 1295 EGGEASVSPEKTSTTSKGKAKRDKASGDVKE----------KKGKGSLGSQGAKDEPEEE 1344
+S S +S++S + +S K G +L + +P
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671
Query: 1345 LQKGMGTVEGGDQSNPKSKKEKKKSDKRK-------KDKEKKEKKKKAKKASTKDSESPS 1397
++ + D ++R+ +D++ ++ +++ DS SPS
Sbjct: 2672 ERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
Query: 1398 QKKKKK 1403
K++++
Sbjct: 2732 HKRRRE 2737
Score = 95.9 bits (237), Expect = 2e-19
Identities = 253/1369 (18%), Positives = 475/1369 (34%), Gaps = 193/1369 (14%)
Query: 166 NTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKA--------S 217
NT SE +E+ + P + + + S SSS D KA S
Sbjct: 1344 NTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSIS 1403
Query: 218 EKILQV------RAASAPAKGTPGKGATPAPPGKAGAVAS----QTKAGKPEEDSESSSE 267
+L R S+ A K P P + S + +G P S S S
Sbjct: 1404 SPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSS 1463
Query: 268 ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESP---------------RKGAAPA 312
TP+ + + +S + + P SP R G+ +
Sbjct: 1464 PGMKDIPRTPS-RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESS 1522
Query: 313 PPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA-PAQAKPSGKAPQVRAAS-APAKESP 370
KT VA+ G+R SS+E D + A P + S +P +A + P ++
Sbjct: 1523 VDQKT---VARTPLGQRSRSG--SSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRS 1577
Query: 371 RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVK 430
R G++P K+ ++ + S SS E D R A A + + P K+P +
Sbjct: 1578 RSGSSPEVDSKS-------RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR 1630
Query: 431 PASTMGM-GPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
G KG GP P G SSS ESS + TA
Sbjct: 1631 ALPRRSRSGSSSKGRGPSPEG-------------------SSSTESSPEHPPKSRTA--- 1668
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA- 548
G+ +P + P +++ + ++ + + S SS S P
Sbjct: 1669 ----RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724
Query: 549 --AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVA 606
+ + + +PA K ++ +++ ++ K R + +P+ G S + S
Sbjct: 1725 RRSPSVSSPEPAEKSRSSRR--RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782
Query: 607 GGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL 666
T+R + S SS+ + +++ V + + G G ++ P + + ++
Sbjct: 1783 RTTRR-RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS---PARQESSRTSSRRR 1838
Query: 667 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT-----SVKKTQAKANPAAAR 721
G++ T K + S + + S S + A+ + ++ S ++++++ +P + R
Sbjct: 1839 RGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRR 1898
Query: 722 APSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNS---TVLARGPASVPSVGKAVA 778
++ +++ A+ +++RS S+ P R S T R + P V +
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRR-- 1956
Query: 779 TAAQAQTGPEEDSGSSEEESD-----SEEEAETLAQVKPSGKTHQIRAALAPAKESP--- 830
++++T P S S S + + + +T + + ++ SP
Sbjct: 1957 -RSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTR 2015
Query: 831 RKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES-----DSDGEAPAAVTSAQVI--KPPLI 883
R+ + TPP S ++ S S S P + + PP I
Sbjct: 2016 RRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAI 2075
Query: 884 ---FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGI 940
+ S +ATP + S R + +++R S P +C +PG+
Sbjct: 2076 RRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGM 2135
Query: 941 ---------------------------------RTNV---------------VTMPTAHP 952
RT+V +++ TA P
Sbjct: 2136 LEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARP 2195
Query: 953 RIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQP 1012
+ A+ A S+ + + + PA ++ + PA+ AA LA + A P
Sbjct: 2196 PPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA----SAAAMNLASARTPAIP 2251
Query: 1013 PVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL--RKPKLPEVQQA-TKAPES---- 1065
A S +A + SP+ T+V N R P P V A + P +
Sbjct: 2252 -TAVNLADSRTPAAAAAMNLASPR-TAVAPSAVNLADPRTPTAPAVNLAGARTPAALAAL 2309
Query: 1066 SDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQS 1125
S + +++ PQ SA+ LVGP + V + ++ +AP+ S
Sbjct: 2310 SLTGSGTPPTAANYPSSSRTPQAPASAN-LVGPRSAHATAPVNIAGSRTAA--ALAPA-S 2365
Query: 1126 LLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTG 1185
L S M P L+ AN + + S ++ D + + M S +
Sbjct: 2366 LTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAP 2425
Query: 1186 GKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTE 1245
+ G P +S P P++ + S+ ++CL+ Q P+ +Q +S T
Sbjct: 2426 SPSSRMGQAPSQSLLPP-AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTT 2484
Query: 1246 LLEQERKKVVDTTKESSRKGWESRKRKLSG-DQPAARTPRSKKKKKLGAGEGGEASVSPE 1304
+ ++ +G QP+A K++ + +S S
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
Query: 1305 KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK--DEPEEELQKGMGTVEGGDQSNPKS 1362
+S++S + +S D S+G+ +PE L++ ++ +
Sbjct: 2545 SSSSSSSSSSSSGSSSSD-----------SEGSSLPVQPEVALKRVPSPTPAPKEAVREG 2593
Query: 1363 KKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1411
+ + KRK+ + +S+ S S S ++ +
Sbjct: 2594 RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Score = 95.1 bits (235), Expect = 4e-19
Identities = 259/1321 (19%), Positives = 477/1321 (36%), Gaps = 153/1321 (11%)
Query: 155 KSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEV 214
++ + + EP +LV E+ S P K G+ SS + +
Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRS-PTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK 217
Query: 215 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEE 274
SE + R +P TP K + K S T A K S+S +S+ S +
Sbjct: 218 HRSESESKKRKHRSP---TP-KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSD 273
Query: 275 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 334
T +++ A + T+ G + +PA S R+G AP ++ G
Sbjct: 274 -TSRSRSRSAAAKTHTTALAGRSPSPA--SGRRGEGDAP---------FSEPGTTSTQRP 321
Query: 335 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 394
SS E + + +P + K K + ++A+ P+ R P PP T P A+ G
Sbjct: 322 SSPETATKQPSSPYEDKDKDK--KEKSATRPSPSPERSSTGPEPPAPT-PLLAERHGGSP 378
Query: 395 EEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP-PGKVG 453
+ + + + + + A+ + P KSP+ P S+ + + P P P KV
Sbjct: 379 QPLATTPLSQEPVNPPSEASPTRDRSPP--KSPEKLPQSSS-----SESSPPSPQPTKVS 431
Query: 454 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-SPAKGPP 512
S+ + S E S S PT ++ +S G + K S +P++
Sbjct: 432 RHASSSPESPKPAPAPGSHREISSS-----PT----SKNRSHGRAKRDKSHSHTPSRRMG 482
Query: 513 QKAGPVAV---QVKAEKPMDNSESSEESSDSADSEEAP--AAMTAAQAKPALKIPQTKAC 567
+ P + ++ P S S S A + Q + + PQ
Sbjct: 483 RSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW 542
Query: 568 PKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG--GTQRPAEDSSSSEESDSE 625
+ NT + R G R T +PA G ++ PA S S
Sbjct: 543 SRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRR 602
Query: 626 EEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV---------LPGKTGPTVTQ 676
++ G+++S + PV+ + +P P + G + ++
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSPVR-RRSRSRSPARRSGRSRSRTPARRGRSRSR 661
Query: 677 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA----------ARAPSAK 726
A + + + +PA+ S +T + + +R P +
Sbjct: 662 TPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRR 721
Query: 727 GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS------------VG 774
G + + + +++RS S P ++ + S+ +R +S S G
Sbjct: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG 781
Query: 775 KAVATAAQAQTGPEED-SGSSEEESDSE---EEAETLAQVKPSGKTHQIRAALAPAKESP 830
+ ++QT P SGSS+ ++ S + + + P K+ +
Sbjct: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH 841
Query: 831 RKGAAPTPPGKTGPSAAQAGKQD--DSGSSSEESDSDGEAPAAVTSAQVI---KPPLI-- 883
K + TPP + ++ QA +Q S ES D E + S PP +
Sbjct: 842 PKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901
Query: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
P +SP+ ++ + +A +PR+ S S++ S S T TP +
Sbjct: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSR---------VTSRTTPRRSRS 952
Query: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE-----GPATQVSKKNPASLPLTQA 998
V R+ P+ S +G+SS + +Q P +V + P L+ +
Sbjct: 953 VSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGS 1012
Query: 999 ALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQS-----TSVQAKGTNKLRKPKL 1053
+K+ ++ + ++ P S + G +T P +S+Q KG ++
Sbjct: 1013 KSPCPQEKSKDS---LVQSCPGS-LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS---- 1064
Query: 1054 PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAE 1113
P+ + T +PE +S S S+ P+G + SR+ + V E A+
Sbjct: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQ---TSPKGGR----------SRSSSPVTELASR 1111
Query: 1114 S--SEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1171
S +D + +L M+P + S +S + P +DS+ + + + K
Sbjct: 1112 SPIRQDRGEFSASPMLKSGMSPEQSRFQSDSS-SYPTVDSNSLLGQSRLETAESKEKMAL 1170
Query: 1172 KPQQAAGMLSPKTGGKEAASGT--TPQKS-------RKPKKGAGNPQASTLALQSNITQC 1222
PQ+ A P+ K + P+ S R P + +S + N
Sbjct: 1171 PPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALP 1230
Query: 1223 LLGQPWPLNEA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAA 1280
Q L E + + ++L+ L E K++ + ESS + E L+ DQ +
Sbjct: 1231 TSSQDEELMEVVEKSEEPAGQILSH-LSSELKEMSTSNFESSPEVEERPAVSLTLDQSQS 1289
Query: 1281 RTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---GA 1337
+ + A G SPE ++ R+ + G E + G LG++ G
Sbjct: 1290 QASLEAVEVPSMASSWGGPHFSPEHKELSN--SPLRENSFGSPLEFRNSGPLGTEMNTGF 1347
Query: 1338 KDEPEEELQKGMGTVEGGDQSNPK--SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1395
E +E+L G +++P K++ +S + + +KA +S + S
Sbjct: 1348 SSEVKEDLN---GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISS 1404
Query: 1396 P 1396
P
Sbjct: 1405 P 1405
Score = 77.4 bits (189), Expect = 9e-14
Identities = 212/1077 (19%), Positives = 363/1077 (33%), Gaps = 140/1077 (12%)
Query: 60 GRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLA------STNSSVL 113
G +R + + TR D +S+S+ + ++ T R S + +
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ 1828
Query: 114 GADLPSSMKEKAKAETEKAG-KTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172
+ SS + + ++ T K S PA K + S + R+S + T L+S
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR---SRTPLISR 1885
Query: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232
S + S S + S + ++ + R + +
Sbjct: 1886 RRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS----RSRTPPVTRRRSRSRTPT 1941
Query: 233 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKA-LLQAKASGKT 291
T + + PP S+T P S S S + + + + + + ++ +T
Sbjct: 1942 TRRRSRSRTPPVTRRRSRSRTP---PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 292 SQVGAASAPAKESP---RKGAAPAPPG------KTGPAVAKAQAGKREEDSQSSSEESDS 342
S V + ++ SP R+ + PP P + + ++ R + S +
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
Query: 343 EEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 402
A + + P +R SA S R +A P + + V S
Sbjct: 2059 PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFS 2118
Query: 403 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 462
S S + ++PLG S G + G GP P + P
Sbjct: 2119 RPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVP----- 2173
Query: 463 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 522
++ + S + + + TA P + G L A+ + PA PV +
Sbjct: 2174 ----ENHAQSRIALALTAISLGTARPPPSMSAAG--LAARMSQVPA--------PVPLMS 2219
Query: 523 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS-AKVAP 581
P N S ++ +A A A A L +T A N + VAP
Sbjct: 2220 LRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAP 2279
Query: 582 VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSV 641
V PR T T+PA + G + PA ++ S
Sbjct: 2280 SAVNLADPR---TPTAPAVN----LAGARTPAALAALS--------------------LT 2312
Query: 642 GKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 701
G G AA+ P Q AP GP +A +
Sbjct: 2313 GSGTPPTAANYPSSSRTPQ--APASANLVGP-----------------------RSAHAT 2347
Query: 702 AQVKTSVKKTQAKANPA----AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNP 757
A V + +T A PA A AP+ G +V +A + R + PP+ +
Sbjct: 2348 APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYE---RVSGRTSPPLLDR 2404
Query: 758 QNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH 817
S R P S PS + + A + P G + +S + PS +
Sbjct: 2405 ARS----RTPPSAPSQSRMTSERAPS---PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSD 2457
Query: 818 QIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESD----SDGEAPAAVT 873
Q R +A + +P G+ G + + AG D +G S + SD P A T
Sbjct: 2458 QSRCLIA--QTTPVAGSQSLSSGAVATTTSSAG--DHNGMLSVPAPGVPHSDVGEPPAST 2513
Query: 874 SAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPAT 933
AQ L + P + +++ + + ++S+ + +S S++ SSSS+SE +
Sbjct: 2514 GAQQ-PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP--- 2569
Query: 934 QCLTPGIRTNVVTMPTAHPRIAPK---------ASMAGASSSKESSRISDGKKQEGPATQ 984
+ P + V PT P+ A + A SSS SS S ++
Sbjct: 2570 --VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS 2627
Query: 985 VSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKG 1044
S + +S + ++ + + P A +P+S G + SP+ +
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRD 2687
Query: 1045 TNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPS 1101
+ L V++ +P+ S + SS S GS G + S H TPS
Sbjct: 2688 SRSL---SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPS-HKRRRETPS 2740
Score = 63.2 bits (152), Expect = 2e-09
Identities = 139/729 (19%), Positives = 248/729 (34%), Gaps = 107/729 (14%)
Query: 739 AAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP--EEDSGSSEE 796
A +AKQ +P KP ++S+ + P K + P E S ++
Sbjct: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK 216
Query: 797 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG 856
+ SE E++ P+ K+ + +K+ RK + T P A ++ D S
Sbjct: 217 KHRSESESKKRKHRSPTPKSKR------KSKDKKRKRSRSTTPAPKSRRAHRSTSAD-SA 269
Query: 857 SSSEESDSDGEAPAAVTSAQVI--KPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASE 914
SSS+ S S + AA T + + P P G P ++ ++ + E
Sbjct: 270 SSSDTSRSRSRSAAAKTHTTALAGRSP----SPASGRRGEGDAPFSEPGTTSTQRPSSPE 325
Query: 915 STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD 974
+ + SS ED+D + T P +P+ S G + +++
Sbjct: 326 TATKQPSSPYEDKDKDKKEKSAT-------------RPSPSPERSSTGPEPPAPTPLLAE 372
Query: 975 GKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGV---DSAVGTLP 1031
+ G + Q A+ PL+Q + SEA P R+ P S S+
Sbjct: 373 ---RHGGSPQPL----ATTPLSQEPVN----PPSEASPTRDRSPPKSPEKLPQSSSSESS 421
Query: 1032 ATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1091
SPQ T V ++ PK AP E SS +S + G +
Sbjct: 422 PPSPQPTKVSRHASSSPESPK--------PAPAPGSHREISSSPTSKNRSHGRAKRDKSH 473
Query: 1092 AHTLVGPTPSRTETLVEETA-AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLD 1150
+HT PSR A A+ P++ S +P + S +
Sbjct: 474 SHT-----PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR-- 526
Query: 1151 SSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTP-------------QK 1197
SP + P + Q+ S + G + S T +
Sbjct: 527 -SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR 585
Query: 1198 SRKPKKGAGNPQASTLALQSNITQCLLGQP---WPLNEAQVQASVVKVLTELLEQERKKV 1254
SR P + + T + T G+ P S V+ + R+
Sbjct: 586 SRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG 645
Query: 1255 VDTTKESSRKGWESRKRKLSGDQPAARTPR---SKKKKKLGAGEGGEASVSPEKTSTTSK 1311
++ +R+G + + +RTP + + + A G S +P + + S+
Sbjct: 646 RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR 705
Query: 1312 GKAKRDKA----------SGDVKEKKGKGSLGSQGAKDEPEEELQKG-MGTVEGGDQSNP 1360
+R ++ SG E+K K + ++ E++K + + S+P
Sbjct: 706 SLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP 765
Query: 1361 KSK------------------KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1402
+SK K+K ++ R+ + K K++ + S S K+
Sbjct: 766 RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ 825
Query: 1403 KKKKTAEQT 1411
K K + Q+
Sbjct: 826 KSKTPSRQS 834
Score = 42.4 bits (98), Expect = 0.003
Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 7/144 (4%)
Query: 1270 KRKLSGDQPAARTPRS------KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV 1323
K + G +PA KK ++L A G S + +S + +A+ K
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV-DGSSFDPQRRAREAKQPAPE 166
Query: 1324 KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1383
K S ++ ++ +K G + ++E+KKS K+KK + + E KK
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
Query: 1384 KAKKASTKDSESPSQKKKKKKKKT 1407
+ ++ T S+ S+ KK+K+ ++
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRS 250
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 101 bits (251), Expect = 6e-21
Identities = 294/1531 (19%), Positives = 551/1531 (35%), Gaps = 221/1531 (14%)
Query: 24 VRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDA---ALQAKKTRVSD 80
V A+ + KEQ +K + ++ + SE ++ E A L A+ +V
Sbjct: 321 VEASEKKKEQEPEKVDTEEDGKA-EVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVEL 379
Query: 81 P----ISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTG 136
P +S S+ EE+ A T ++ V+ S+++E+ + + + +T
Sbjct: 380 PSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETA 439
Query: 137 NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPG---MVSA 193
S+P L+ + + AEP+ + ET G P GA P +
Sbjct: 440 GSVP-------AEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKP 492
Query: 194 GQADSSSEDTSSSSDETDVEVKASEKILQV----RAASAPAKGTPGKGATPAPPGKAGAV 249
+ S + SS + V+ +K+ + + KG G G + G+ V
Sbjct: 493 PEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEES--GEHTQV 550
Query: 250 ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGA 309
+ + + E+ ESS+ + EE T K L + + G+ + GA S K+ R+G
Sbjct: 551 PADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEE-GATSDGEKK--REGV 607
Query: 310 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAA-SAPAKE 368
P K K E D + ++ S + ++ S +++ + P E
Sbjct: 608 TPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPE 667
Query: 369 SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 428
P++ + + A + VG ++ +R S + + + GK +
Sbjct: 668 EPKRKVDTSVSWE-----ALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKE 722
Query: 429 VKPASTM-GMGPLGKGAGPVPPGKVGPATPSAQVGKWE---------EDSESSSEESSDS 478
+ G G G P + G T V WE + S+S EE S+
Sbjct: 723 TGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSED 782
Query: 479 S------DGEVPTAVAPAQEKSLGNILQ-------AKPTSSPAKGPPQKAGPVAVQ---- 521
S + P P +E+S +I + +P + P + AGP
Sbjct: 783 SIAGSGVEHSTPDT-EPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDS 841
Query: 522 -VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 580
V A P+ ++ E M A QA+ + + P+ KA + + + ++V
Sbjct: 842 DVPAVVPLSEYDAVEREK-----------MEAQQAQKSAEQPEQKAATEVSKELSESQVH 890
Query: 581 PVRVGTQAPRKAGTAT---SPAGSSPAVAGGTQRPAEDSSS------SEESDSEEEKTGL 631
+ +A T SP+ S +V ++ +++ E +EEE +
Sbjct: 891 MMAAAVADGTRAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTV 950
Query: 632 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP-------TVTQVKAEKQ-- 682
+ + + V A + + TA L + G T V A Q
Sbjct: 951 TEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLT 1010
Query: 683 EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK---GTISAPGKVVTAA 739
+ +++EE + +E ++ ++TQ A + GT P V+
Sbjct: 1011 DSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGT-GGPEDVLQPV 1069
Query: 740 AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE--EDSGSSEEE 797
+A+ P + + + V+ + A QT PE E + E
Sbjct: 1070 QRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTES 1129
Query: 798 SDSEE-----EAETLAQVKPSGKTHQIRAALAPAK-----ESPRKGAAPTP----PGKTG 843
+S E +AETLA VK + A+ P +S G+ P PG T
Sbjct: 1130 IESSELVTTCQAETLAGVKSQEMV--MEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQ 1187
Query: 844 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP----LIFVDPNRSPAGPAATPA 899
+++ +S +S G A AQ +PP +F + + + T
Sbjct: 1188 KDEIVEIHEENEVASGTQS---GGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLE 1244
Query: 900 QAQ---AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP 956
+ T +E T + E +P + L I T + +A
Sbjct: 1245 HTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVAL 1304
Query: 957 KASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVAR 1016
K E + ++ KK + Q K+P S P+ + + + ++ +EA+P
Sbjct: 1305 KG---------EGTEEAECKKDDALELQSHAKSPPS-PVEREMVVQVEREKTEAEPTHVN 1354
Query: 1017 TQPSSGVDSAVGTLPATSPQSTSVQ-------AKGTNKLRKPKLPEV--QQATKAPESSD 1067
+ ++AV S Q AK + L P + ++A
Sbjct: 1355 EEKLEH-ETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQ 1413
Query: 1068 DSEDSSDSSSGSEED---GEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQ 1124
SE S ++ +EE+ GE ++ TL P+ ++EE ++E +ED P +
Sbjct: 1414 SSEASFTLTAAAEEEKVLGETANILETGETL---EPAGAHLVLEEKSSEKNEDFAAHPGE 1470
Query: 1125 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1184
+ T + QA K+TP + S+ ++ D +G++ + + + +
Sbjct: 1471 DAVP-------TGPDCQA-KSTPVIVSA---TTKKGLSSDLEGEKTTSLKWKSDEVDEQV 1519
Query: 1185 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQ---------PWPLNEAQV 1235
+E + +P+ G + + L NI Q + Q +E Q
Sbjct: 1520 ACQEVKVSVAIE-DLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQT 1578
Query: 1236 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1295
QA V+K ++ QE +K + + S++ K + A S K +
Sbjct: 1579 QAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMS--- 1635
Query: 1296 GGEASVSPEKTSTTS-KGKAKRDKASGDV---KEKKGKGSLGSQGAKDEPE--------E 1343
EAS EKT T +G D+ +V E++G G+ G K PE E
Sbjct: 1636 --EAS---EKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGA----GTKSVPEDDGHALLAE 1686
Query: 1344 ELQKGM----GTVEGGDQSNPKSK-----------------------KEKKKSDKRKKDK 1376
++K + +G D +P+++ K+K+K D ++ +
Sbjct: 1687 RIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVEL 1746
Query: 1377 EKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1407
++ + ++ KA T ++ QK++++ K+
Sbjct: 1747 QEGKVHSESDKAITPQAQEELQKQERESAKS 1777
Score = 73.2 bits (178), Expect = 2e-12
Identities = 235/1170 (20%), Positives = 390/1170 (33%), Gaps = 235/1170 (20%)
Query: 74 KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAG 133
KK + P + + +++E E + S LGA +S + + K TEK
Sbjct: 186 KKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPS-----LGAGEAASKESEPKQSTEKPE 240
Query: 134 KT-------GNSMPHPATGKTVANLLSGKSPRKSAEPS--ANTTLVSETEEEGSV-PAFG 183
+T P +G+ V ++ EPS A + T E GS F
Sbjct: 241 ETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFF 300
Query: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPP 243
G ED EV+ASEK + P K
Sbjct: 301 TQGWAGWRKKTSFRKPKED----------EVEASEK----KKEQEPEK------VDTEED 340
Query: 244 GKAGAVASQTKAGK---PEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 300
GKA + + A + P+E +ES+ E +E E K L ++ QV + P
Sbjct: 341 GKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYE----KVELPSE-----EQVSGSQGP 391
Query: 301 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
++E P A K + A + +EE +E E A + P+ + ++
Sbjct: 392 SEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMD 451
Query: 361 AA---SAPAKE------------SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 405
A + PAKE P +GA +P K ++ G E SS+E
Sbjct: 452 AEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKV---LSKPPEGVVSEVEMLSSQER 508
Query: 406 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGK-GAGPVPPGKVGPATPSAQVGKW 464
+ + +K L S +K S G GK G G G+ QV
Sbjct: 509 -------MKVQGSPLKKLFTSTGLKKLS--GKKQKGKRGGGDEESGE------HTQVPAD 553
Query: 465 EEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGP------- 517
DS+ + S +S E P + EK L + Q A +K
Sbjct: 554 SPDSQEEQKGESSASSPEEPEEIT-CLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWAS 612
Query: 518 ----VAVQVKAEKPMDNSESSE---ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 570
V + + +P ++ + E S + S E+ A+ + K +++ P+ + +K
Sbjct: 613 FKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRK 672
Query: 571 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR------------------- 611
+T+ S + A + VG+ R ++S P GG +
Sbjct: 673 VDTSVSWE-ALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAG 731
Query: 612 -----PAEDSSSSEESDSEEEKTGLAV------TVGQAKSVGKGLQVKAASVPVKGSLGQ 660
P + SSS E++ S E G++ V K L+ K+ +
Sbjct: 732 SQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEH 791
Query: 661 GTAPVLPG----------------KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQV 704
T PG K P Q +A ++ + E DS+ A P
Sbjct: 792 STPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSE 851
Query: 705 KTSVKKTQAKANPA--AARAPSAKGT---------------ISAPGKVVTAAAQAKQRSP 747
+V++ + +A A +A P K +A AA ++RSP
Sbjct: 852 YDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSP 911
Query: 748 SKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETL 807
S + V P A+A EE E E +EEE T+
Sbjct: 912 SWISASVTEPLEQ------------------VEAEAALLTEE---VLEREVIAEEEPPTV 950
Query: 808 AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE 867
+ P + + ++ A+ +P A T GP A+ G + S++EE+
Sbjct: 951 TEPLPENREARGDTVVSEAELTPE---AVTAAETAGPLGAEEGTE---ASAAEETTEMVS 1004
Query: 868 APAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP---RKARASESTARSSSSES 924
A + +T + P+ + ATP Q P + R ++ ++ + +
Sbjct: 1005 AVSQLTDS-----------PDTT---EEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKV 1050
Query: 925 EDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ 984
++E +P T + A A +E + S KK+ +
Sbjct: 1051 KEESQLPGT---------------GGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLK 1095
Query: 985 VSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA------TSPQST 1038
V + + P TQ KV+ Q E+ + S V T A S +
Sbjct: 1096 VDAQEAKTEPFTQG--KVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMV 1153
Query: 1039 SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGP 1098
QA + + P E +T + D E+ E G +S T
Sbjct: 1154 MEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEA 1213
Query: 1099 TPSRTE--------TLVEETAAESSEDDVV 1120
P++ E EET +S +D +
Sbjct: 1214 VPAQKERPPAPSSFVFQEETKEQSKMEDTL 1243
Score = 60.8 bits (146), Expect = 9e-09
Identities = 252/1348 (18%), Positives = 466/1348 (34%), Gaps = 196/1348 (14%)
Query: 29 EVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS 88
EV+ S Q+ Q L ++T G+K+K + + P + +S
Sbjct: 499 EVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQ 558
Query: 89 EEEE-EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
EE++ E+ A + + + + +E A ++ EK K P + K
Sbjct: 559 EEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEK--KREGVTPWASFKKM 616
Query: 148 VANLLSGKSPR-----------KSAEPSANTTLVSETEEE--GSVP----------AFGA 184
V + P KSA S+ + SE +EE GSV +
Sbjct: 617 VTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTS 676
Query: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPG--KGATPAP 242
+ ++ G + + SSS +E + + A GT G G+
Sbjct: 677 VSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHD 736
Query: 243 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA----- 297
PG+ + S +AG P E S+ ES TP K+ + + + S G+
Sbjct: 737 PGQGSS--SPEQAGSPTEGEGVSTWESF-KRLVTPRKKSKSKLEEKSEDSIAGSGVEHST 793
Query: 298 --SAPAKESP----------RKGAAPAPPGKTGPAVAKAQAGKREEDSQ-------SSSE 338
+ P KE R+ P + P G E+DS S +
Sbjct: 794 PDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYD 853
Query: 339 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK-----GAAPAPPRKTGP--------- 384
+ E+ QA+ S + P+ +AA+ +KE AA A +
Sbjct: 854 AVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSW 913
Query: 385 -AAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV-KPLGKSPQVKPASTMGMGPL-- 440
+A+ + +Q E + E +RE +A V +PL ++ + + + + L
Sbjct: 914 ISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTP 973
Query: 441 -----GKGAGPVPPGKVGPATPSAQVGKWEE------DSESSSEESSDSSDGEVPTAVAP 489
+ AGP+ + A+ + + + DS ++EE++ + E
Sbjct: 974 EAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIE 1033
Query: 490 AQEKSLGNILQA------KPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESS--EESSDSA 541
QE+ +LQA + + P G P+ + +AE+P + +E+S ++ +D
Sbjct: 1034 EQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVV 1093
Query: 542 DSEEAPAAMTAAQAKPALKIPQT--KACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 599
+A A T + + + QT ++ K T S + + + QA AG +
Sbjct: 1094 LKVDAQEAKTEPFTQGKV-VGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEM 1152
Query: 600 GSSPAVA-GGTQRPAEDSSSSEESDSEEEKTGLA-----VTVGQAKSVGKGLQ---VKAA 650
A+ + P + + ++ + G V + + V G Q +A
Sbjct: 1153 VMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAE 1212
Query: 651 SVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK 710
+VP Q P P V Q + ++Q E + E +D +E + + + +
Sbjct: 1213 AVPA-----QKERPPAPSSF---VFQEETKEQSKMEDTLEHTD-KEVSVETVSILSKTEG 1263
Query: 711 TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 770
TQ A + G + T ++++ ++V + + +
Sbjct: 1264 TQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKV-TEVALKGEGTEEAECKKDDALEL 1322
Query: 771 PSVGKAVATAAQAQTGPEEDSGSSEEE----SDSEEEAETLAQVKPSGKTHQIRAALAPA 826
S K+ + + + + + +E E ++ + E ET V ++ P
Sbjct: 1323 QSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPI 1382
Query: 827 KESPRKGAA--PTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIF 884
+ ++ ++ +PP G A K S EA +T+A + ++
Sbjct: 1383 IDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSS---------EASFTLTAAAE-EEKVLG 1432
Query: 885 VDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 944
N G PA A + + +E A ED +P T
Sbjct: 1433 ETANILETGETLEPAGAHLVLEEKSSEKNEDFAAHPG-----EDAVP----------TGP 1477
Query: 945 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQ-----EGPATQVSKKNPASLPLT-QA 998
+ P I + G SS E + + K + E A Q K + A L +
Sbjct: 1478 DCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPEN 1537
Query: 999 ALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ 1058
+ L K+S+ + +T VD V T + TS +L
Sbjct: 1538 GILELETKSSKLVQNIIQT----AVDQFVRTEETATEMLTS------------ELQTQAH 1581
Query: 1059 ATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTE-TLVEETAAESSED 1117
KA DS D+ +E++GE PQ + T + +E T V + ++ S+D
Sbjct: 1582 VIKA--------DSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKD 1633
Query: 1118 DVVAPSQSL-------------LSGYMTPGLTPANSQASKATPKLDSSPSVS-----STL 1159
A +++ L + P +K+ P+ D ++ S +
Sbjct: 1634 MSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLV 1693
Query: 1160 AAKDDPDGKQEAKPQQAAGML--SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1217
K+D G P+ L + +GG S T +K K+ A + + S
Sbjct: 1694 EPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHS 1753
Query: 1218 NITQCLLGQPWPLNEAQVQASVVKVLTE 1245
+ + Q + Q + S LTE
Sbjct: 1754 ESDKAITPQAQEELQKQERESAKSELTE 1781
Score = 35.4 bits (80), Expect = 0.39
Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 17/140 (12%)
Query: 1287 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ 1346
K LGAGE P++++ + KR+++ ++ G + K+E EE+ +
Sbjct: 216 KDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEE-CKEEGEEKQE 274
Query: 1347 KGMGTVEGGDQSNPKSK----------------KEKKKSDKRKKDKEKKEKKKKAKKAST 1390
K S S+ ++K K K+D+ + +KKK ++
Sbjct: 275 KEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEK 334
Query: 1391 KDSESPSQKKKKKKKKTAEQ 1410
D+E + + +K TA +
Sbjct: 335 VDTEEDGKAEVASEKLTASE 354
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 101 bits (251), Expect = 6e-21
Identities = 294/1531 (19%), Positives = 551/1531 (35%), Gaps = 221/1531 (14%)
Query: 24 VRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDA---ALQAKKTRVSD 80
V A+ + KEQ +K + ++ + SE ++ E A L A+ +V
Sbjct: 223 VEASEKKKEQEPEKVDTEEDGKA-EVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVEL 281
Query: 81 P----ISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTG 136
P +S S+ EE+ A T ++ V+ S+++E+ + + + +T
Sbjct: 282 PSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETA 341
Query: 137 NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPG---MVSA 193
S+P L+ + + AEP+ + ET G P GA P +
Sbjct: 342 GSVP-------AEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKP 394
Query: 194 GQADSSSEDTSSSSDETDVEVKASEKILQV----RAASAPAKGTPGKGATPAPPGKAGAV 249
+ S + SS + V+ +K+ + + KG G G + G+ V
Sbjct: 395 PEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEES--GEHTQV 452
Query: 250 ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGA 309
+ + + E+ ESS+ + EE T K L + + G+ + GA S K+ R+G
Sbjct: 453 PADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEE-GATSDGEKK--REGV 509
Query: 310 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAA-SAPAKE 368
P K K E D + ++ S + ++ S +++ + P E
Sbjct: 510 TPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPE 569
Query: 369 SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 428
P++ + + A + VG ++ +R S + + + GK +
Sbjct: 570 EPKRKVDTSVSWE-----ALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKE 624
Query: 429 VKPASTM-GMGPLGKGAGPVPPGKVGPATPSAQVGKWE---------EDSESSSEESSDS 478
+ G G G P + G T V WE + S+S EE S+
Sbjct: 625 TGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSED 684
Query: 479 S------DGEVPTAVAPAQEKSLGNILQ-------AKPTSSPAKGPPQKAGPVAVQ---- 521
S + P P +E+S +I + +P + P + AGP
Sbjct: 685 SIAGSGVEHSTPDT-EPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDS 743
Query: 522 -VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 580
V A P+ ++ E M A QA+ + + P+ KA + + + ++V
Sbjct: 744 DVPAVVPLSEYDAVEREK-----------MEAQQAQKSAEQPEQKAATEVSKELSESQVH 792
Query: 581 PVRVGTQAPRKAGTAT---SPAGSSPAVAGGTQRPAEDSSS------SEESDSEEEKTGL 631
+ +A T SP+ S +V ++ +++ E +EEE +
Sbjct: 793 MMAAAVADGTRAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTV 852
Query: 632 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP-------TVTQVKAEKQ-- 682
+ + + V A + + TA L + G T V A Q
Sbjct: 853 TEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLT 912
Query: 683 EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK---GTISAPGKVVTAA 739
+ +++EE + +E ++ ++TQ A + GT P V+
Sbjct: 913 DSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGT-GGPEDVLQPV 971
Query: 740 AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE--EDSGSSEEE 797
+A+ P + + + V+ + A QT PE E + E
Sbjct: 972 QRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTES 1031
Query: 798 SDSEE-----EAETLAQVKPSGKTHQIRAALAPAK-----ESPRKGAAPTP----PGKTG 843
+S E +AETLA VK + A+ P +S G+ P PG T
Sbjct: 1032 IESSELVTTCQAETLAGVKSQEMV--MEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQ 1089
Query: 844 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP----LIFVDPNRSPAGPAATPA 899
+++ +S +S G A AQ +PP +F + + + T
Sbjct: 1090 KDEIVEIHEENEVASGTQS---GGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLE 1146
Query: 900 QAQ---AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP 956
+ T +E T + E +P + L I T + +A
Sbjct: 1147 HTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVAL 1206
Query: 957 KASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVAR 1016
K E + ++ KK + Q K+P S P+ + + + ++ +EA+P
Sbjct: 1207 KG---------EGTEEAECKKDDALELQSHAKSPPS-PVEREMVVQVEREKTEAEPTHVN 1256
Query: 1017 TQPSSGVDSAVGTLPATSPQSTSVQ-------AKGTNKLRKPKLPEV--QQATKAPESSD 1067
+ ++AV S Q AK + L P + ++A
Sbjct: 1257 EEKLEH-ETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQ 1315
Query: 1068 DSEDSSDSSSGSEED---GEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQ 1124
SE S ++ +EE+ GE ++ TL P+ ++EE ++E +ED P +
Sbjct: 1316 SSEASFTLTAAAEEEKVLGETANILETGETL---EPAGAHLVLEEKSSEKNEDFAAHPGE 1372
Query: 1125 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1184
+ T + QA K+TP + S+ ++ D +G++ + + + +
Sbjct: 1373 DAVP-------TGPDCQA-KSTPVIVSA---TTKKGLSSDLEGEKTTSLKWKSDEVDEQV 1421
Query: 1185 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQ---------PWPLNEAQV 1235
+E + +P+ G + + L NI Q + Q +E Q
Sbjct: 1422 ACQEVKVSVAIE-DLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQT 1480
Query: 1236 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1295
QA V+K ++ QE +K + + S++ K + A S K +
Sbjct: 1481 QAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMS--- 1537
Query: 1296 GGEASVSPEKTSTTS-KGKAKRDKASGDV---KEKKGKGSLGSQGAKDEPE--------E 1343
EAS EKT T +G D+ +V E++G G+ G K PE E
Sbjct: 1538 --EAS---EKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGA----GTKSVPEDDGHALLAE 1588
Query: 1344 ELQKGM----GTVEGGDQSNPKSK-----------------------KEKKKSDKRKKDK 1376
++K + +G D +P+++ K+K+K D ++ +
Sbjct: 1589 RIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVEL 1648
Query: 1377 EKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1407
++ + ++ KA T ++ QK++++ K+
Sbjct: 1649 QEGKVHSESDKAITPQAQEELQKQERESAKS 1679
Score = 73.2 bits (178), Expect = 2e-12
Identities = 235/1170 (20%), Positives = 390/1170 (33%), Gaps = 235/1170 (20%)
Query: 74 KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAG 133
KK + P + + +++E E + S LGA +S + + K TEK
Sbjct: 88 KKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPS-----LGAGEAASKESEPKQSTEKPE 142
Query: 134 KT-------GNSMPHPATGKTVANLLSGKSPRKSAEPS--ANTTLVSETEEEGSV-PAFG 183
+T P +G+ V ++ EPS A + T E GS F
Sbjct: 143 ETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFF 202
Query: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPP 243
G ED EV+ASEK + P K
Sbjct: 203 TQGWAGWRKKTSFRKPKED----------EVEASEK----KKEQEPEK------VDTEED 242
Query: 244 GKAGAVASQTKAGK---PEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 300
GKA + + A + P+E +ES+ E +E E K L ++ QV + P
Sbjct: 243 GKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYE----KVELPSE-----EQVSGSQGP 293
Query: 301 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
++E P A K + A + +EE +E E A + P+ + ++
Sbjct: 294 SEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMD 353
Query: 361 AA---SAPAKE------------SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 405
A + PAKE P +GA +P K ++ G E SS+E
Sbjct: 354 AEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKV---LSKPPEGVVSEVEMLSSQER 410
Query: 406 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGK-GAGPVPPGKVGPATPSAQVGKW 464
+ + +K L S +K S G GK G G G+ QV
Sbjct: 411 -------MKVQGSPLKKLFTSTGLKKLS--GKKQKGKRGGGDEESGE------HTQVPAD 455
Query: 465 EEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGP------- 517
DS+ + S +S E P + EK L + Q A +K
Sbjct: 456 SPDSQEEQKGESSASSPEEPEEIT-CLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWAS 514
Query: 518 ----VAVQVKAEKPMDNSESSE---ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 570
V + + +P ++ + E S + S E+ A+ + K +++ P+ + +K
Sbjct: 515 FKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRK 574
Query: 571 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR------------------- 611
+T+ S + A + VG+ R ++S P GG +
Sbjct: 575 VDTSVSWE-ALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAG 633
Query: 612 -----PAEDSSSSEESDSEEEKTGLAV------TVGQAKSVGKGLQVKAASVPVKGSLGQ 660
P + SSS E++ S E G++ V K L+ K+ +
Sbjct: 634 SQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEH 693
Query: 661 GTAPVLPG----------------KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQV 704
T PG K P Q +A ++ + E DS+ A P
Sbjct: 694 STPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSE 753
Query: 705 KTSVKKTQAKANPA--AARAPSAKGT---------------ISAPGKVVTAAAQAKQRSP 747
+V++ + +A A +A P K +A AA ++RSP
Sbjct: 754 YDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSP 813
Query: 748 SKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETL 807
S + V P A+A EE E E +EEE T+
Sbjct: 814 SWISASVTEPLEQ------------------VEAEAALLTEE---VLEREVIAEEEPPTV 852
Query: 808 AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE 867
+ P + + ++ A+ +P A T GP A+ G + S++EE+
Sbjct: 853 TEPLPENREARGDTVVSEAELTPE---AVTAAETAGPLGAEEGTE---ASAAEETTEMVS 906
Query: 868 APAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP---RKARASESTARSSSSES 924
A + +T + P+ + ATP Q P + R ++ ++ + +
Sbjct: 907 AVSQLTDS-----------PDTT---EEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKV 952
Query: 925 EDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ 984
++E +P T + A A +E + S KK+ +
Sbjct: 953 KEESQLPGT---------------GGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLK 997
Query: 985 VSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA------TSPQST 1038
V + + P TQ KV+ Q E+ + S V T A S +
Sbjct: 998 VDAQEAKTEPFTQG--KVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMV 1055
Query: 1039 SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGP 1098
QA + + P E +T + D E+ E G +S T
Sbjct: 1056 MEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEA 1115
Query: 1099 TPSRTE--------TLVEETAAESSEDDVV 1120
P++ E EET +S +D +
Sbjct: 1116 VPAQKERPPAPSSFVFQEETKEQSKMEDTL 1145
Score = 60.8 bits (146), Expect = 9e-09
Identities = 252/1348 (18%), Positives = 466/1348 (34%), Gaps = 196/1348 (14%)
Query: 29 EVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS 88
EV+ S Q+ Q L ++T G+K+K + + P + +S
Sbjct: 401 EVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQ 460
Query: 89 EEEE-EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
EE++ E+ A + + + + +E A ++ EK K P + K
Sbjct: 461 EEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEK--KREGVTPWASFKKM 518
Query: 148 VANLLSGKSPR-----------KSAEPSANTTLVSETEEE--GSVP----------AFGA 184
V + P KSA S+ + SE +EE GSV +
Sbjct: 519 VTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTS 578
Query: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPG--KGATPAP 242
+ ++ G + + SSS +E + + A GT G G+
Sbjct: 579 VSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHD 638
Query: 243 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA----- 297
PG+ + S +AG P E S+ ES TP K+ + + + S G+
Sbjct: 639 PGQGSS--SPEQAGSPTEGEGVSTWESF-KRLVTPRKKSKSKLEEKSEDSIAGSGVEHST 695
Query: 298 --SAPAKESP----------RKGAAPAPPGKTGPAVAKAQAGKREEDSQ-------SSSE 338
+ P KE R+ P + P G E+DS S +
Sbjct: 696 PDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYD 755
Query: 339 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK-----GAAPAPPRKTGP--------- 384
+ E+ QA+ S + P+ +AA+ +KE AA A +
Sbjct: 756 AVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSW 815
Query: 385 -AAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV-KPLGKSPQVKPASTMGMGPL-- 440
+A+ + +Q E + E +RE +A V +PL ++ + + + + L
Sbjct: 816 ISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTP 875
Query: 441 -----GKGAGPVPPGKVGPATPSAQVGKWEE------DSESSSEESSDSSDGEVPTAVAP 489
+ AGP+ + A+ + + + DS ++EE++ + E
Sbjct: 876 EAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIE 935
Query: 490 AQEKSLGNILQA------KPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESS--EESSDSA 541
QE+ +LQA + + P G P+ + +AE+P + +E+S ++ +D
Sbjct: 936 EQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVV 995
Query: 542 DSEEAPAAMTAAQAKPALKIPQT--KACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 599
+A A T + + + QT ++ K T S + + + QA AG +
Sbjct: 996 LKVDAQEAKTEPFTQGKV-VGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEM 1054
Query: 600 GSSPAVA-GGTQRPAEDSSSSEESDSEEEKTGLA-----VTVGQAKSVGKGLQ---VKAA 650
A+ + P + + ++ + G V + + V G Q +A
Sbjct: 1055 VMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAE 1114
Query: 651 SVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK 710
+VP Q P P V Q + ++Q E + E +D +E + + + +
Sbjct: 1115 AVPA-----QKERPPAPSSF---VFQEETKEQSKMEDTLEHTD-KEVSVETVSILSKTEG 1165
Query: 711 TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 770
TQ A + G + T ++++ ++V + + +
Sbjct: 1166 TQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKV-TEVALKGEGTEEAECKKDDALEL 1224
Query: 771 PSVGKAVATAAQAQTGPEEDSGSSEEE----SDSEEEAETLAQVKPSGKTHQIRAALAPA 826
S K+ + + + + + +E E ++ + E ET V ++ P
Sbjct: 1225 QSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPI 1284
Query: 827 KESPRKGAA--PTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIF 884
+ ++ ++ +PP G A K S EA +T+A + ++
Sbjct: 1285 IDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSS---------EASFTLTAAAE-EEKVLG 1334
Query: 885 VDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 944
N G PA A + + +E A ED +P T
Sbjct: 1335 ETANILETGETLEPAGAHLVLEEKSSEKNEDFAAHPG-----EDAVP----------TGP 1379
Query: 945 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQ-----EGPATQVSKKNPASLPLT-QA 998
+ P I + G SS E + + K + E A Q K + A L +
Sbjct: 1380 DCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPEN 1439
Query: 999 ALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ 1058
+ L K+S+ + +T VD V T + TS +L
Sbjct: 1440 GILELETKSSKLVQNIIQT----AVDQFVRTEETATEMLTS------------ELQTQAH 1483
Query: 1059 ATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTE-TLVEETAAESSED 1117
KA DS D+ +E++GE PQ + T + +E T V + ++ S+D
Sbjct: 1484 VIKA--------DSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKD 1535
Query: 1118 DVVAPSQSL-------------LSGYMTPGLTPANSQASKATPKLDSSPSVS-----STL 1159
A +++ L + P +K+ P+ D ++ S +
Sbjct: 1536 MSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLV 1595
Query: 1160 AAKDDPDGKQEAKPQQAAGML--SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1217
K+D G P+ L + +GG S T +K K+ A + + S
Sbjct: 1596 EPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHS 1655
Query: 1218 NITQCLLGQPWPLNEAQVQASVVKVLTE 1245
+ + Q + Q + S LTE
Sbjct: 1656 ESDKAITPQAQEELQKQERESAKSELTE 1683
Score = 35.4 bits (80), Expect = 0.39
Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 17/140 (12%)
Query: 1287 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ 1346
K LGAGE P++++ + KR+++ ++ G + K+E EE+ +
Sbjct: 118 KDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEE-CKEEGEEKQE 176
Query: 1347 KGMGTVEGGDQSNPKSK----------------KEKKKSDKRKKDKEKKEKKKKAKKAST 1390
K S S+ ++K K K+D+ + +KKK ++
Sbjct: 177 KEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEK 236
Query: 1391 KDSESPSQKKKKKKKKTAEQ 1410
D+E + + +K TA +
Sbjct: 237 VDTEEDGKAEVASEKLTASE 256
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 100 bits (250), Expect = 8e-21
Identities = 247/1327 (18%), Positives = 454/1327 (34%), Gaps = 135/1327 (10%)
Query: 69 AALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAE 128
A +A T +D + SS E A A + +T +S G++ + + + ++
Sbjct: 2 AGSEATTTSTADSKVITASSMSSETTVAPAAGSN----TTTASTTGSETTTILIKASETT 57
Query: 129 TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKP 188
T + + P P +T +SG ++ T GS ++A
Sbjct: 58 TASTAGSETTTPSPTGSQTTIVSISGSE-------------ITTTSTAGSENTTVSSAGS 104
Query: 189 GMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGA 248
G +A A S S +++ S+ T V + +E + SA T T +
Sbjct: 105 GTTTASMAGSESTISTAGSETTTVSITGTETTM----VSAMGSETTTNSTTSSETTVTST 160
Query: 249 VASQTKAGKPEEDSESSSEESSDSE---EETPAAKALLQAKASGKTSQVGAASAPAKESP 305
S+T SE+++ ++DSE T ++ A +T A +
Sbjct: 161 AGSETTT-VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVS 219
Query: 306 RKGAAPAPPGKTGPAVAKAQAGKREEDSQSS-SEESDSEEEAPAQAKPSGKAPQVRAASA 364
G+ TG A E + S+ E+ A ++ S + AAS
Sbjct: 220 TAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAST 279
Query: 365 PAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 424
E A KT A+ E + +S+ S+ + +G
Sbjct: 280 ---EDSETNTAFTEDSKTTTAST-----TGFETTAASTTGSEPTMASTMGSETTMASTIG 331
Query: 425 -KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSES--SSEESSDSSDG 481
++ +V AS+ G+ + VG T + E + S SE S+DS+ G
Sbjct: 332 PETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTG 391
Query: 482 ---------------------EVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 520
E T E + +I ++ T++ +G A V
Sbjct: 392 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 451
Query: 521 QVKAEKPMDNSE----SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS 576
+ SE S+ +S + S E T A K T +T T ++
Sbjct: 452 FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTG--SETTTASN 509
Query: 577 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES--------DSEEEK 628
+ V T +T + ++ A G++ + SE + +
Sbjct: 510 TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 569
Query: 629 TGLAVTVGQAK-SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSES 687
TGL T + S + A + G GT G T V E++ +
Sbjct: 570 TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA--STAGSETTTVSTADSENTTA 627
Query: 688 SEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSP 747
S +DSE +AS +T+ T + A+ S T+S T +
Sbjct: 628 S--TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT---GS 682
Query: 748 SKVKPPVRNPQNSTVLARGPASVPSV---GKAVATAAQAQTGPEEDSGSSEEESDSEEEA 804
+ + +TV A G + S G + ++T +GS + +E
Sbjct: 683 ERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSE 742
Query: 805 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS-------GS 857
T A + S +T + + +G+ T TG A GS
Sbjct: 743 ITTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 801
Query: 858 SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTA 917
+ + + G V++A K +F + N + T ++ ST STA
Sbjct: 802 ETTMASTIGSETTKVSTAS-SKMTTVFTE-NSETTIASTTASETTTVSTAGSETIPASTA 859
Query: 918 RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKK 977
S ++ + + T T G T + ++ + + A S+ ++ ++G +
Sbjct: 860 GSETTTTTSTEGSETTTASTEGSETTTASTESS------ETTTATTIGSETTTASTEGSE 913
Query: 978 QEGPATQVSKKNPASLPLTQ-AALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQ 1036
+T+ S+ AS ++ + + + A + T +S S + T+ T +
Sbjct: 914 TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSE 973
Query: 1037 STSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLV 1096
+ +V A+G+ + + T A S+ SE ++ S++GSE +G+++ T V
Sbjct: 974 TITVSAEGSETTTVTTMG--SETTTA--STAGSETTTVSTAGSETTTASIEGSET--TTV 1027
Query: 1097 GPTPSRTETL------VEETAAESSEDDVVAPSQSLLSG-YMTPGLTPANSQASKATPKL 1149
T S T T+ T+ E SE V + S + Y T T S T +
Sbjct: 1028 SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTV 1087
Query: 1150 DSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQ 1209
++ S ++T + D + +G + T G E + S+ +
Sbjct: 1088 STTGSETTTAST---ADLETTTVSTSGSGTTTASTAGSETTT-VYITGSKTTTASTEGSE 1143
Query: 1210 ASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT-TKESSRKGWES 1268
A+T++ S+ T + + + V T + E + + SS G E+
Sbjct: 1144 ATTVSTTSSET---------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1194
Query: 1269 RKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG 1328
G + + E AS + +T+T S ++ + A E
Sbjct: 1195 TTTSTEGSETTTAS--------TAGSETTTASTAGSETTTASTSGSETNTACTTGSETST 1246
Query: 1329 KGSLGSQ 1335
S GS+
Sbjct: 1247 PSSAGSE 1253
Score = 30.8 bits (68), Expect = 9.6
Identities = 40/233 (17%), Positives = 80/233 (34%), Gaps = 7/233 (3%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
+T+ S+E E T + AST S + + +++ E T + T +S
Sbjct: 1134 TTTASTEGSEATTVSTTSSETTTASTTGSEM-TTVFTTVSETTTVSTIGSEATTSS---- 1188
Query: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
A G + S +A + + T + T + A + ++ +++S+
Sbjct: 1189 AAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPS 1248
Query: 203 TSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDS 262
++ S T + + I + A G T +GA A+ T
Sbjct: 1249 SAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVL 1308
Query: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
+++ S TP + + + T+ AP + A+ PG
Sbjct: 1309 TKATDVSIQPITNTPMSGT--RTTGTRLTASSSVTMAPGMDFTASAASHTVPG 1359
>gi|112821681 G protein-regulated inducer of neurite outgrowth 1 [Homo
sapiens]
Length = 1008
Score = 100 bits (250), Expect = 8e-21
Identities = 217/978 (22%), Positives = 354/978 (36%), Gaps = 167/978 (17%)
Query: 171 SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPA 230
S+ + + P PGM S ++ S + + +S SD + +P
Sbjct: 48 SQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSP-----TCFSPQ 102
Query: 231 KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK 290
+ +P K A T +GKPE S +E S S++ P + K K
Sbjct: 103 E-SPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKS-SDDRNP----MFLEKMDFK 156
Query: 291 TSQVGAASAPAKESP---RKG---------------AAPAPPGKTGPAVAKAQ----AGK 328
+S+ +++ KE P RK P PG+ P + + GK
Sbjct: 157 SSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGK 216
Query: 329 REEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA-PAKESPRKGAA--PAPPRKTGPA 385
+ S + +E P + + P KE PR P K P
Sbjct: 217 VDPLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPT 276
Query: 386 AAQ----VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 441
+A+ V GK+ D S + E++ + + + +P G ++ P S+ GP+
Sbjct: 277 SAEKVDLVLSGKR--DPGPSGKADPMPLESMDSASTGKTEP-GLLGKLIPGSSGKNGPVS 333
Query: 442 KGAGPVPPGKVGPATPS-------AQVGKWE------EDSE-------SSSEESSDSSDG 481
G G PG +G P+ A VG E EDS +SS E S
Sbjct: 334 SGTGA--PGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGH 391
Query: 482 EVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA 541
TA A SL N+ P SS K P G + + + + +E S
Sbjct: 392 TDTTASAKTDLTSLKNV---DPMSS-GKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGK 447
Query: 542 DSEEAPAAM--TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP- 598
+P +++ + + K +K N +S K PV G PR GTA P
Sbjct: 448 AGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGPPS 507
Query: 599 ------------------------AGSSPAVAGGTQRP----AEDSSSSEESDSEEEKTG 630
+G + A G P ED S ++D+ G
Sbjct: 508 AVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQG 567
Query: 631 LAVTVGQAKSV-GKGLQVKAASV-PVK----GSLGQGTAPVLPGKTGPTVTQVKAEKQED 684
+V++G+ S GK + V + V PV ++ +G LP + G VT KA+ +
Sbjct: 568 DSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRAS 627
Query: 685 SES-------SEEESDSEEAAASPAQ-----VKTSVKKTQAKANPAAAR----APSAKGT 728
++ +E + +E AA+P + +K + K +P + R S KG
Sbjct: 628 GKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGE 687
Query: 729 ISAPGKVVTAAAQAKQRSPS--KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTG 786
+ GK +A ++ K SPS KV P S + +S + + +A++ G
Sbjct: 688 PVSLGKADSAPSR-KTESPSLGKVVP------LSLEKTKPSSSSRQLDRKALGSARSPEG 740
Query: 787 PEEDSGSSEEESD--SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGP 844
G E +++ S EA +L Q + AA A P + AAP P +T
Sbjct: 741 ARGSEGRVEPKAEPVSSTEASSLGQ-------KDLEAAGAERSPCP-EAAAPPPGPRTRD 792
Query: 845 SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAA 904
+ +A + S D+ +A A + + P + P G A + A A
Sbjct: 793 NFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSP----MSPQDGAGGSAFSFQAAPRA 848
Query: 905 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP--RIAPKASMAG 962
+P R + ++E T+ + G T P A P R+ P +++A
Sbjct: 849 PSPPSRRDAGLQVSLGAAE---------TRSVATGPMTPQAAAPPAFPEVRVRPGSALAA 899
Query: 963 ASSSKESSR-ISDGKKQE--------GPATQVSKKNPASLPLTQAALKVLAQKASEAQPP 1013
A + E + + D E G A +V A + ++ ++ + A PP
Sbjct: 900 AVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAIQKHLERQIEEHGRQGAPAPPP 959
Query: 1014 VARTQPSSGVDSAVGTLP 1031
AR P G +V T P
Sbjct: 960 AARAGP--GRSGSVRTAP 975
Score = 36.2 bits (82), Expect = 0.23
Identities = 104/517 (20%), Positives = 169/517 (32%), Gaps = 68/517 (13%)
Query: 890 SPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPT 949
SPA P TP Q+ + ++ + S S P+ C +P + T+
Sbjct: 53 SPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSKETLEA 112
Query: 950 AHPRIA--PKASMAG----ASSSKESSRISDGKK------------QEGPATQVSKKNPA 991
I+ P+A+ +G SS K + SD + ++ +T + K++P
Sbjct: 113 HGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPG 172
Query: 992 SLP-----LTQAALKVLAQKASEAQP----PVARTQPSSGVDSAVGTLPATSPQSTSVQA 1042
S T A + K P P+ + G V L ++ + S +
Sbjct: 173 SSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRK 232
Query: 1043 KGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSR 1102
+ LRK + ++ S S E K L G
Sbjct: 233 EDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLSGKRDPG 292
Query: 1103 TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAK 1162
+ ES + ++ L G + PG + N S T S + T
Sbjct: 293 PSGKADPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPGSLGRLDPTCLGM 352
Query: 1163 DDPD--GKQEAKP-----QQAAGMLSPKTGGK---------EAASGTTPQKSRKPKKGAG 1206
DP G E P + G + P + G+ AS T S K
Sbjct: 353 ADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASAKTDLTSLKNVDPMS 412
Query: 1207 NPQASTLALQSNITQCLLGQPWPLNEAQVQ-ASVVKVLT------ELLEQERKKVVD--T 1257
+ + ++L C G+P L+ Q + SV K T + + R+ + +
Sbjct: 413 SGKVDPVSLGKMDPMCS-GKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGS 471
Query: 1258 TKESSRKGWESRKRKLS------GDQPAART---PRSKKKKKLGAGEGGEAS------VS 1302
K SS K K + GD + T P + K + G+G S V+
Sbjct: 472 RKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVA 531
Query: 1303 PEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKD 1339
K + T+ GKA+ + KGK G G D
Sbjct: 532 SGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQGD 568
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 100 bits (248), Expect = 1e-20
Identities = 252/1298 (19%), Positives = 457/1298 (35%), Gaps = 139/1298 (10%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS-PRKSAEPSA 165
+T +S G++ + + + ++ T + + P P +T +SG S S
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE 74
Query: 166 NTTL---------VSETEEEGSVPAFGA--------AAKPGMVSAGQADSSSEDTSSS-- 206
NTT+ S E +V G+ + MVSA +++++ T+SS
Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSET 134
Query: 207 -------SDETDVEVKASEKILQVRAAS-APAKGTPGKGATPAPPGKAGAVASQTKAGKP 258
S+ T V SE A S A T G T + + T
Sbjct: 135 TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG--- 191
Query: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318
SE+++ ++ SE T + AS S+ AAS E+ + A G
Sbjct: 192 ---SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA-------G 241
Query: 319 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP---QVRAASAPAKE---SPRK 372
+ AG E + +S+E+S++ +K + + + AAS E +
Sbjct: 242 SETTVSTAG--SETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
G+ GP +V E + ++ S++ R + V G + A
Sbjct: 300 GSETTMASTIGPETTKVSTASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTA 356
Query: 433 STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQ 491
S MG +T S + S SE ++ S++G E T
Sbjct: 357 SIMGS---------------ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAP 547
E + +I ++ T++ +G A V + SE S+ +S + S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 548 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 607
T A K T +T T ++ + V T +T + ++ A
Sbjct: 462 ETTTVTTAGSETKTAYTTG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519
Query: 608 GTQRPAEDSSSSEES--------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSL 658
G++ + SE + + TGL T + S + A +
Sbjct: 520 GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 579
Query: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
G GT G T V E++ +S +DSE +AS +T+ T +
Sbjct: 580 GSGTTAA--STAGSETTTVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTT 635
Query: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GK 775
A+ S T+S T + + + +TV A G + S G
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGT 692
Query: 776 AVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 835
+ ++T +GS + +E T A + S +T + + +G+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSE 751
Query: 836 PTPPGKTGPSAAQAGKQDDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN 888
T TG A GS + + + G V++A K +F + N
Sbjct: 752 TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-N 809
Query: 889 RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 948
+ T ++ ST STA S ++ + + T T G T +
Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869
Query: 949 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKA 1007
++ + + A S+ ++ ++G + +T+ S+ AS ++ + +
Sbjct: 870 SS------ETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
+ A + T +S S + T+ T ++ +V A+G+ + + T A S+
Sbjct: 924 TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STA 979
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETAAESSEDDVVA 1121
SE ++ S++GSE +G+++ T V T S T T+ T+ E SE V
Sbjct: 980 GSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037
Query: 1122 PSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
+ S + Y T T S T + ++ S ++T + D + +G
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTT 1094
Query: 1181 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1240
+ T G E + S+ +A+T++ S+ T + + +
Sbjct: 1095 TASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------TTASTTGSEMT 1144
Query: 1241 KVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQ-PAARTPRSKKKKKLGAG-EGG 1297
V T + E + + SS G E+ G + A T S+ AG E
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT 1204
Query: 1298 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1335
AS + +T+T S ++ + A E S GS+
Sbjct: 1205 TASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242
Score = 84.7 bits (208), Expect = 6e-16
Identities = 220/1161 (18%), Positives = 399/1161 (34%), Gaps = 150/1161 (12%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE---------------- 312
Query: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
+++ +++SS+ T V SE I AS T T + A + S+
Sbjct: 313 ------TTKVSTASSEVTTVFAAGSETI----RASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
T DS + SE ++ S E + A + + S G+ + + +
Sbjct: 363 TST-----DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417
Query: 313 PPGKTGPAVAKA--QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
G AV+ + + + S S+ E + + V A + K +
Sbjct: 418 TEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAY 477
Query: 371 RKGAAPAPPRKTGPAAAQV-QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
G+ TG V +G D+ ++S E S+ A++A + + +
Sbjct: 478 TTGSETTTASNTGLETTTVFTIG---SDTTTASTEG-SETTAVSATGSEMTTVSTEGSEN 533
Query: 430 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
ST G V + T S + + S + +E ++DS++G TA +
Sbjct: 534 TTVST-----TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
A ++ T S A A +E ++ SE ++ S S E A
Sbjct: 589 AGSET--------TTVSTA----DSENTTASTADSETTSASTTGSETTTASTTSSETTTA 636
Query: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
T + + T + +TT S + G++ T S GS V+
Sbjct: 637 ST--EGSETTTVSTTDSETTMVSTTGSERTITSTEGSET-----TTVSATGSETTVS--- 686
Query: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG-KGLQVKAASVPVKGSLGQGTAPVLPG 668
E S ++ S + E T ++ T + + +G ++ AS+
Sbjct: 687 ---TEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI---------------- 727
Query: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
TG T E E + +S E SE +AS +T+ T + A+ S
Sbjct: 728 -TGSETTTASTEGSETTTASTE--GSETTSASTTGSETTTASTTSSETTMASIMGSETTM 784
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
S G T + A + + V + T +A AS + + A ++T P
Sbjct: 785 ASTIGSETTKVSTASSKMTT-----VFTENSETTIASTTASETT----TVSTAGSETIPA 835
Query: 789 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 848
+GS + S E +ET +T + ES A T +T ++ +
Sbjct: 836 STAGSETTTTTSTEGSETTTASTEGSET------TTASTESSETTTATTIGSETTTASTE 889
Query: 849 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908
+ + + E+ + + +T+ S G T A + + T
Sbjct: 890 GSETTTTSTEGSETTTASTEGSEITTV--------------STTGSETTTASTEGSETTT 935
Query: 909 KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE 968
+ S++ SE V G T VT + A A + S
Sbjct: 936 ASTEGSELTTVSTTGSETITV------SAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989
Query: 969 SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1028
S + + T VS + ++ + ++ T S +AV
Sbjct: 990 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE--TTAVY 1047
Query: 1029 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
T T ++T+ +G+ + + S+ D E ++ S+SGS G
Sbjct: 1048 T---TGSETTTTSTEGS----ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 1089 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG--LTPANSQASKAT 1146
+++ T V T S+T T + E SE V+ + S + T G +T + S+ T
Sbjct: 1101 SET--TTVYITGSKTTT----ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154
Query: 1147 --PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1204
+ S + SS ++ + ++ A+ S T A S TT + G
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST----AG 1210
Query: 1205 AGNPQASTLALQSNITQCLLG 1225
+ AST ++N T C G
Sbjct: 1211 SETTTASTSGSETN-TACTTG 1230
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/802 (19%), Positives = 262/802 (32%), Gaps = 73/802 (9%)
Query: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 621
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 622 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 681
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 742 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 793
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 794 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 839
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 840 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 899
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 959
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 960 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1019
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1020 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1078
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1079 SEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1138
SE +G S +T V T S T T V T E++ + +S T T
Sbjct: 521 SEMTTVSTEG--SENTTVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTT 575
Query: 1139 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1198
+S T ++ S ++T++ D + + S T G E + +T
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSE 632
Query: 1199 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1258
G+ + S T + +T E V T
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATG 680
Query: 1259 KES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGK 1313
E+ S +G + ++G + + + + + EG E AS++ +T+T S
Sbjct: 681 SETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG 739
Query: 1314 AKRDKASGDVKEKKGKGSLGSQ 1335
++ AS + E + GS+
Sbjct: 740 SETTTASTEGSETTSASTTGSE 761
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 100 bits (248), Expect = 1e-20
Identities = 252/1298 (19%), Positives = 457/1298 (35%), Gaps = 139/1298 (10%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS-PRKSAEPSA 165
+T +S G++ + + + ++ T + + P P +T +SG S S
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE 74
Query: 166 NTTL---------VSETEEEGSVPAFGA--------AAKPGMVSAGQADSSSEDTSSS-- 206
NTT+ S E +V G+ + MVSA +++++ T+SS
Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSET 134
Query: 207 -------SDETDVEVKASEKILQVRAAS-APAKGTPGKGATPAPPGKAGAVASQTKAGKP 258
S+ T V SE A S A T G T + + T
Sbjct: 135 TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG--- 191
Query: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318
SE+++ ++ SE T + AS S+ AAS E+ + A G
Sbjct: 192 ---SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA-------G 241
Query: 319 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP---QVRAASAPAKE---SPRK 372
+ AG E + +S+E+S++ +K + + + AAS E +
Sbjct: 242 SETTVSTAG--SETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
G+ GP +V E + ++ S++ R + V G + A
Sbjct: 300 GSETTMASTIGPETTKVSTASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTA 356
Query: 433 STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQ 491
S MG +T S + S SE ++ S++G E T
Sbjct: 357 SIMGS---------------ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAP 547
E + +I ++ T++ +G A V + SE S+ +S + S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 548 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 607
T A K T +T T ++ + V T +T + ++ A
Sbjct: 462 ETTTVTTAGSETKTAYTTG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519
Query: 608 GTQRPAEDSSSSEES--------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSL 658
G++ + SE + + TGL T + S + A +
Sbjct: 520 GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 579
Query: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
G GT G T V E++ +S +DSE +AS +T+ T +
Sbjct: 580 GSGTTAA--STAGSETTTVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTT 635
Query: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GK 775
A+ S T+S T + + + +TV A G + S G
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGT 692
Query: 776 AVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 835
+ ++T +GS + +E T A + S +T + + +G+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSE 751
Query: 836 PTPPGKTGPSAAQAGKQDDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN 888
T TG A GS + + + G V++A K +F + N
Sbjct: 752 TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-N 809
Query: 889 RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 948
+ T ++ ST STA S ++ + + T T G T +
Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869
Query: 949 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKA 1007
++ + + A S+ ++ ++G + +T+ S+ AS ++ + +
Sbjct: 870 SS------ETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
+ A + T +S S + T+ T ++ +V A+G+ + + T A S+
Sbjct: 924 TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STA 979
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETAAESSEDDVVA 1121
SE ++ S++GSE +G+++ T V T S T T+ T+ E SE V
Sbjct: 980 GSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037
Query: 1122 PSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
+ S + Y T T S T + ++ S ++T + D + +G
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTT 1094
Query: 1181 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1240
+ T G E + S+ +A+T++ S+ T + + +
Sbjct: 1095 TASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------TTASTTGSEMT 1144
Query: 1241 KVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQ-PAARTPRSKKKKKLGAG-EGG 1297
V T + E + + SS G E+ G + A T S+ AG E
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT 1204
Query: 1298 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1335
AS + +T+T S ++ + A E S GS+
Sbjct: 1205 TASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242
Score = 84.7 bits (208), Expect = 6e-16
Identities = 220/1161 (18%), Positives = 399/1161 (34%), Gaps = 150/1161 (12%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE---------------- 312
Query: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
+++ +++SS+ T V SE I AS T T + A + S+
Sbjct: 313 ------TTKVSTASSEVTTVFAAGSETI----RASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
T DS + SE ++ S E + A + + S G+ + + +
Sbjct: 363 TST-----DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417
Query: 313 PPGKTGPAVAKA--QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
G AV+ + + + S S+ E + + V A + K +
Sbjct: 418 TEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAY 477
Query: 371 RKGAAPAPPRKTGPAAAQV-QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
G+ TG V +G D+ ++S E S+ A++A + + +
Sbjct: 478 TTGSETTTASNTGLETTTVFTIG---SDTTTASTEG-SETTAVSATGSEMTTVSTEGSEN 533
Query: 430 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
ST G V + T S + + S + +E ++DS++G TA +
Sbjct: 534 TTVST-----TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
A ++ T S A A +E ++ SE ++ S S E A
Sbjct: 589 AGSET--------TTVSTA----DSENTTASTADSETTSASTTGSETTTASTTSSETTTA 636
Query: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
T + + T + +TT S + G++ T S GS V+
Sbjct: 637 ST--EGSETTTVSTTDSETTMVSTTGSERTITSTEGSET-----TTVSATGSETTVS--- 686
Query: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG-KGLQVKAASVPVKGSLGQGTAPVLPG 668
E S ++ S + E T ++ T + + +G ++ AS+
Sbjct: 687 ---TEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI---------------- 727
Query: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
TG T E E + +S E SE +AS +T+ T + A+ S
Sbjct: 728 -TGSETTTASTEGSETTTASTE--GSETTSASTTGSETTTASTTSSETTMASIMGSETTM 784
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
S G T + A + + V + T +A AS + + A ++T P
Sbjct: 785 ASTIGSETTKVSTASSKMTT-----VFTENSETTIASTTASETT----TVSTAGSETIPA 835
Query: 789 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 848
+GS + S E +ET +T + ES A T +T ++ +
Sbjct: 836 STAGSETTTTTSTEGSETTTASTEGSET------TTASTESSETTTATTIGSETTTASTE 889
Query: 849 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908
+ + + E+ + + +T+ S G T A + + T
Sbjct: 890 GSETTTTSTEGSETTTASTEGSEITTV--------------STTGSETTTASTEGSETTT 935
Query: 909 KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE 968
+ S++ SE V G T VT + A A + S
Sbjct: 936 ASTEGSELTTVSTTGSETITV------SAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989
Query: 969 SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1028
S + + T VS + ++ + ++ T S +AV
Sbjct: 990 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE--TTAVY 1047
Query: 1029 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
T T ++T+ +G+ + + S+ D E ++ S+SGS G
Sbjct: 1048 T---TGSETTTTSTEGS----ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 1089 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG--LTPANSQASKAT 1146
+++ T V T S+T T + E SE V+ + S + T G +T + S+ T
Sbjct: 1101 SET--TTVYITGSKTTT----ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154
Query: 1147 --PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1204
+ S + SS ++ + ++ A+ S T A S TT + G
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST----AG 1210
Query: 1205 AGNPQASTLALQSNITQCLLG 1225
+ AST ++N T C G
Sbjct: 1211 SETTTASTSGSETN-TACTTG 1230
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/802 (19%), Positives = 262/802 (32%), Gaps = 73/802 (9%)
Query: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 621
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 622 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 681
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 742 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 793
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 794 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 839
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 840 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 899
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 959
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 960 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1019
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1020 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1078
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1079 SEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1138
SE +G S +T V T S T T V T E++ + +S T T
Sbjct: 521 SEMTTVSTEG--SENTTVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTT 575
Query: 1139 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1198
+S T ++ S ++T++ D + + S T G E + +T
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSE 632
Query: 1199 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1258
G+ + S T + +T E V T
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATG 680
Query: 1259 KES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGK 1313
E+ S +G + ++G + + + + + EG E AS++ +T+T S
Sbjct: 681 SETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG 739
Query: 1314 AKRDKASGDVKEKKGKGSLGSQ 1335
++ AS + E + GS+
Sbjct: 740 SETTTASTEGSETTSASTTGSE 761
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 100 bits (248), Expect = 1e-20
Identities = 252/1298 (19%), Positives = 457/1298 (35%), Gaps = 139/1298 (10%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS-PRKSAEPSA 165
+T +S G++ + + + ++ T + + P P +T +SG S S
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE 74
Query: 166 NTTL---------VSETEEEGSVPAFGA--------AAKPGMVSAGQADSSSEDTSSS-- 206
NTT+ S E +V G+ + MVSA +++++ T+SS
Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSET 134
Query: 207 -------SDETDVEVKASEKILQVRAAS-APAKGTPGKGATPAPPGKAGAVASQTKAGKP 258
S+ T V SE A S A T G T + + T
Sbjct: 135 TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG--- 191
Query: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318
SE+++ ++ SE T + AS S+ AAS E+ + A G
Sbjct: 192 ---SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA-------G 241
Query: 319 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP---QVRAASAPAKE---SPRK 372
+ AG E + +S+E+S++ +K + + + AAS E +
Sbjct: 242 SETTVSTAG--SETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
G+ GP +V E + ++ S++ R + V G + A
Sbjct: 300 GSETTMASTIGPETTKVSTASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTA 356
Query: 433 STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQ 491
S MG +T S + S SE ++ S++G E T
Sbjct: 357 SIMGS---------------ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAP 547
E + +I ++ T++ +G A V + SE S+ +S + S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 548 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 607
T A K T +T T ++ + V T +T + ++ A
Sbjct: 462 ETTTVTTAGSETKTAYTTG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519
Query: 608 GTQRPAEDSSSSEES--------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSL 658
G++ + SE + + TGL T + S + A +
Sbjct: 520 GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 579
Query: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
G GT G T V E++ +S +DSE +AS +T+ T +
Sbjct: 580 GSGTTAA--STAGSETTTVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTT 635
Query: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GK 775
A+ S T+S T + + + +TV A G + S G
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGT 692
Query: 776 AVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 835
+ ++T +GS + +E T A + S +T + + +G+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSE 751
Query: 836 PTPPGKTGPSAAQAGKQDDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN 888
T TG A GS + + + G V++A K +F + N
Sbjct: 752 TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-N 809
Query: 889 RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 948
+ T ++ ST STA S ++ + + T T G T +
Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869
Query: 949 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKA 1007
++ + + A S+ ++ ++G + +T+ S+ AS ++ + +
Sbjct: 870 SS------ETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
+ A + T +S S + T+ T ++ +V A+G+ + + T A S+
Sbjct: 924 TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STA 979
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETAAESSEDDVVA 1121
SE ++ S++GSE +G+++ T V T S T T+ T+ E SE V
Sbjct: 980 GSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037
Query: 1122 PSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
+ S + Y T T S T + ++ S ++T + D + +G
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTT 1094
Query: 1181 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1240
+ T G E + S+ +A+T++ S+ T + + +
Sbjct: 1095 TASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------TTASTTGSEMT 1144
Query: 1241 KVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQ-PAARTPRSKKKKKLGAG-EGG 1297
V T + E + + SS G E+ G + A T S+ AG E
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT 1204
Query: 1298 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1335
AS + +T+T S ++ + A E S GS+
Sbjct: 1205 TASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242
Score = 84.7 bits (208), Expect = 6e-16
Identities = 220/1161 (18%), Positives = 399/1161 (34%), Gaps = 150/1161 (12%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE---------------- 312
Query: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
+++ +++SS+ T V SE I AS T T + A + S+
Sbjct: 313 ------TTKVSTASSEVTTVFAAGSETI----RASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
T DS + SE ++ S E + A + + S G+ + + +
Sbjct: 363 TST-----DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417
Query: 313 PPGKTGPAVAKA--QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
G AV+ + + + S S+ E + + V A + K +
Sbjct: 418 TEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAY 477
Query: 371 RKGAAPAPPRKTGPAAAQV-QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
G+ TG V +G D+ ++S E S+ A++A + + +
Sbjct: 478 TTGSETTTASNTGLETTTVFTIG---SDTTTASTEG-SETTAVSATGSEMTTVSTEGSEN 533
Query: 430 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
ST G V + T S + + S + +E ++DS++G TA +
Sbjct: 534 TTVST-----TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
A ++ T S A A +E ++ SE ++ S S E A
Sbjct: 589 AGSET--------TTVSTA----DSENTTASTADSETTSASTTGSETTTASTTSSETTTA 636
Query: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
T + + T + +TT S + G++ T S GS V+
Sbjct: 637 ST--EGSETTTVSTTDSETTMVSTTGSERTITSTEGSET-----TTVSATGSETTVS--- 686
Query: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG-KGLQVKAASVPVKGSLGQGTAPVLPG 668
E S ++ S + E T ++ T + + +G ++ AS+
Sbjct: 687 ---TEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI---------------- 727
Query: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
TG T E E + +S E SE +AS +T+ T + A+ S
Sbjct: 728 -TGSETTTASTEGSETTTASTE--GSETTSASTTGSETTTASTTSSETTMASIMGSETTM 784
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
S G T + A + + V + T +A AS + + A ++T P
Sbjct: 785 ASTIGSETTKVSTASSKMTT-----VFTENSETTIASTTASETT----TVSTAGSETIPA 835
Query: 789 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 848
+GS + S E +ET +T + ES A T +T ++ +
Sbjct: 836 STAGSETTTTTSTEGSETTTASTEGSET------TTASTESSETTTATTIGSETTTASTE 889
Query: 849 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908
+ + + E+ + + +T+ S G T A + + T
Sbjct: 890 GSETTTTSTEGSETTTASTEGSEITTV--------------STTGSETTTASTEGSETTT 935
Query: 909 KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE 968
+ S++ SE V G T VT + A A + S
Sbjct: 936 ASTEGSELTTVSTTGSETITV------SAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989
Query: 969 SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1028
S + + T VS + ++ + ++ T S +AV
Sbjct: 990 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE--TTAVY 1047
Query: 1029 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
T T ++T+ +G+ + + S+ D E ++ S+SGS G
Sbjct: 1048 T---TGSETTTTSTEGS----ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 1089 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG--LTPANSQASKAT 1146
+++ T V T S+T T + E SE V+ + S + T G +T + S+ T
Sbjct: 1101 SET--TTVYITGSKTTT----ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154
Query: 1147 --PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1204
+ S + SS ++ + ++ A+ S T A S TT + G
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST----AG 1210
Query: 1205 AGNPQASTLALQSNITQCLLG 1225
+ AST ++N T C G
Sbjct: 1211 SETTTASTSGSETN-TACTTG 1230
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/802 (19%), Positives = 262/802 (32%), Gaps = 73/802 (9%)
Query: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 621
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 622 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 681
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 742 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 793
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 794 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 839
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 840 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 899
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 959
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 960 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1019
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1020 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1078
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1079 SEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1138
SE +G S +T V T S T T V T E++ + +S T T
Sbjct: 521 SEMTTVSTEG--SENTTVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTT 575
Query: 1139 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1198
+S T ++ S ++T++ D + + S T G E + +T
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSE 632
Query: 1199 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1258
G+ + S T + +T E V T
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATG 680
Query: 1259 KES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGK 1313
E+ S +G + ++G + + + + + EG E AS++ +T+T S
Sbjct: 681 SETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG 739
Query: 1314 AKRDKASGDVKEKKGKGSLGSQ 1335
++ AS + E + GS+
Sbjct: 740 SETTTASTEGSETTSASTTGSE 761
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 98.6 bits (244), Expect = 4e-20
Identities = 236/1128 (20%), Positives = 379/1128 (33%), Gaps = 146/1128 (12%)
Query: 81 PISTSESSEEEEEA---------EAETAKATPRLASTN-SSVLGADLPSSMKEKAKAE-T 129
P S++ S EE A ++ T T LA T+ S LG+ + ++ +
Sbjct: 4 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63
Query: 130 EKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPG 189
+ K +S P A TV L +G +P S + + S + E ++P G+ KPG
Sbjct: 64 SEESKASHSSPD-AMATTV--LPAGSTPSVLVGDSTPSPISSGSMETTALP--GSTTKPG 118
Query: 190 MVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAV 249
+ ++ S+ SS + AS V S + PG T A PG
Sbjct: 119 L-----SEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG----- 168
Query: 250 ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGA 309
S T G +E + S S +P + T S P
Sbjct: 169 -STTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTT 227
Query: 310 A--------PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 361
A P P + AG +S++ S + A P+
Sbjct: 228 ASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPT-------T 280
Query: 362 ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVK 421
SA + S +P+ T +A G EE + S S + + +
Sbjct: 281 TSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHS--SPGSTQTMHFPESDTTS 338
Query: 422 PLGKSPQVKPAST---MGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS--SEESS 476
G+ +ST + P A P + S + + S +S SEES+
Sbjct: 339 GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 398
Query: 477 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 536
S + T +S ++L + T+SP + + + S +
Sbjct: 399 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHS 458
Query: 537 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 596
S S + +PA+ T++ +++ P T+TTA T P + +T
Sbjct: 459 SPRSPATTLSPASTTSSGVSEESTTSRSR--PGSTHTTAFPD------STTTPGLSRHST 510
Query: 597 SPAGSSPAVAGGTQRPAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 651
+ + SSP T PA ++S S S S T A++ G ++ G +
Sbjct: 511 T-SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQE----- 564
Query: 652 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 711
T PG T T+ + + S + +V +S
Sbjct: 565 --------STTFHSNPGSTHTTLFP-------------DSTTSSGIVEASTRVHSSTGSP 603
Query: 712 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 771
+ +PA++ +P +G +A + A+ PS PV + ST R P S P
Sbjct: 604 RTTLSPASSTSPGLQGESTA-FQTHPASTHTTPSPPSTATAPV---EESTTYHRSPGSTP 659
Query: 772 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPR 831
+ A+ +G E S D+ + A SG+ + ++P
Sbjct: 660 TTH---FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE-- 714
Query: 832 KGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 891
P T P ++A + SS S + +PA++TS V + + S
Sbjct: 715 --ITTLPGSTTTPGLSEAST---TFYSSPRSPTTTLSPASMTSLGVGE------ESTTSR 763
Query: 892 AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAH 951
+ P +T + AST + EST SSS E + T + T T H
Sbjct: 764 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV-FPHSTTTSVHGEEPT--TFH 820
Query: 952 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQ 1011
R A + S S + G PA+L + +S
Sbjct: 821 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 880
Query: 1012 PPVARTQPSSGVDSAVG---------------TLPATSPQSTSVQAKGTNKLRKPKLPEV 1056
+ S VG TLP SP + S+ K T P+ P+
Sbjct: 881 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG-SPTTPSLSEKSTTFYTSPRSPD- 938
Query: 1057 QQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSE 1116
AT +P ++ SS SEE S HT P + T L +E S
Sbjct: 939 --ATLSPATTT-------SSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS- 988
Query: 1117 DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1164
SQ ++PG T A+S ++T SSP + T DD
Sbjct: 989 ------SQGSTEATLSPGSTTASSLGQQST-TFHSSPGDTETTLLPDD 1029
Score = 74.3 bits (181), Expect = 8e-13
Identities = 146/741 (19%), Positives = 265/741 (35%), Gaps = 100/741 (13%)
Query: 530 NSESSEESSDSADSEEAPAAMTAAQAKPAL--KIPQTKACPKKTNTTASAKVAPVRVGTQ 587
+ ES+ + ++ + + TAA A + + T+ + ++T S + +
Sbjct: 13 SEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHS 72
Query: 588 APRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 647
+P T PAGS+P+V G P+ SS S E+ T + GL
Sbjct: 73 SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMET-----------TALPGSTTKPGLSE 121
Query: 648 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 707
K+ + ++P P T + + E+S +S S A P ++
Sbjct: 122 KSTTF--------YSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG---ST 170
Query: 708 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN----PQNSTVL 763
++ + A+ +P T +PG TA++ + + +P P N+T
Sbjct: 171 TMPGLSQESTASHSSPGPTDTTLSPGS-TTASSLGPEYTTFHSRPGSTETTLLPDNTTAS 229
Query: 764 ARGPASVP----------SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPS 813
AS+P ++ A +T Q ++ S S +++ T A V+PS
Sbjct: 230 GLLEASMPVHSSTRSPHTTLSPAGSTTRQGES-TTFHSWPSSKDTRPAPPTTTSAFVEPS 288
Query: 814 GKTHQIRAALAPAKESPRKGAAPTPPGKT----GPSAAQA---GKQDDSGSSSEESDSDG 866
+H +++ S R + T P + Q + D + EES +
Sbjct: 289 TTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSH 348
Query: 867 EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESED 926
+ S+ + +P + P +T S+ R+ ESTA SS ++
Sbjct: 349 SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG 408
Query: 927 EDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVS 986
V+PA + ++ +P +S + +++ S + G + S
Sbjct: 409 TIVLPA---------RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSS 459
Query: 987 KKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTN 1046
++PA+ T + + SE + +R++P S T P ST+ +
Sbjct: 460 PRSPAT---TLSPASTTSSGVSE-ESTTSRSRPGS-------THTTAFPDSTTTPGLSRH 508
Query: 1047 KLRKPKLPEVQQATKAPESSDDSEDS-----SDSSSGSEEDGEGP--------------- 1086
P T P S+ S S S SSSGS + P
Sbjct: 509 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 568
Query: 1087 -QGAKSAHTLVGPTPSRTETLVEET----AAESSEDDVVAPSQSL---LSGYMTPGLT-P 1137
S HT + P + + +VE + ++ S ++P+ S L G T T P
Sbjct: 569 HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 628
Query: 1138 ANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA--AGMLSPKT--GGKEAASGT 1193
A++ + + P ++P ST + P + +G T ASGT
Sbjct: 629 ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT 688
Query: 1194 TPQKSRKPKKGAGNPQASTLA 1214
TP + G G S ++
Sbjct: 689 TPSSAHSTTSGRGESTTSRIS 709
Score = 72.8 bits (177), Expect = 2e-12
Identities = 184/917 (20%), Positives = 301/917 (32%), Gaps = 188/917 (20%)
Query: 95 EAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSM-PHPATGKTVANLLS 153
E+ T+++ P + S P +E + G T ++ PH T +
Sbjct: 758 ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTS-----VH 812
Query: 154 GKSPRK--SAEPSANTTLVSE-------TEEEGSVPAFGAAAKPGM-VSAGQADSSSEDT 203
G+ P S S +TTL +E TEE + P A+ + G+ + AD E T
Sbjct: 813 GEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEEST 872
Query: 204 S--SSSDETDVEVKASEKILQ-VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAG---- 256
+ SSS T ++ + + S P++ +P T PG + K+
Sbjct: 873 TFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYT 932
Query: 257 ---------KPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 307
P + S E S + P + S TS + + S
Sbjct: 933 SPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGS 992
Query: 308 GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK 367
A PG T + S ++S + +P + + P S +
Sbjct: 993 TEATLSPGST--------------TASSLGQQSTTFHSSPGDTETT-LLPDDTITSGLVE 1037
Query: 368 ESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP 427
S ++ T A+ G QEE + S S SD A + +
Sbjct: 1038 ASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY 1097
Query: 428 QVKPASTMGMGPLGKGAGPVPPGKVGPAT----PSAQVGKWEEDSESSSEESSDSSDGEV 483
+P+ST P T S +G+ EE + + SS G
Sbjct: 1098 HSRPSST-------------------PTTHFSASSTTLGRSEEST------TVHSSPGAT 1132
Query: 484 PTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADS 543
TA+ P +S ++L +PT+SP + + + S + S S D+
Sbjct: 1133 GTALFPT--RSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 1190
Query: 544 EEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP 603
+PA+ T++ ++ P T+TTA G+ T P S
Sbjct: 1191 TLSPASTTSSGVSEESTTSHSR--PGSTHTTAFP---------------GSTTMPGVSQE 1233
Query: 604 AVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTA 663
+ A + + D++ S S + A S+G S S G
Sbjct: 1234 STASHSSPGSTDTTLSPGSTT-------------ASSLGP------ESTTFHSSPGSTET 1274
Query: 664 PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP 723
+LP T + E S + S SPA T+ + P
Sbjct: 1275 TLLPDNT------TASGLLEASTPVHSSTGSPHTTLSPAG-----STTRQGESTTFQSWP 1323
Query: 724 SAKGTISAPGKVVTAAAQ---AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780
S+K T+ AP +A + SPS P +ST L R S VATA
Sbjct: 1324 SSKDTMPAPPTTTSAFVELSTTSHGSPSST-PTTHFSASSTTLGRSEESTTVHSSPVATA 1382
Query: 781 AQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 840
SG EE + A + PG
Sbjct: 1383 TTPSPARSTTSGLVEEST-----------------------------------AYHSSPG 1407
Query: 841 KTGP-----SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 895
T S+ +G+ ++S +S + +P + TSA V +P P G
Sbjct: 1408 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP-----GSI 1462
Query: 896 ATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA------------TQCLTPGIRTN 943
AT ++++T R+ ESTA SS ++ +PA T ++PG
Sbjct: 1463 ATTHFPESSTT--SGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMET 1520
Query: 944 VVTMPTAHPRIAPKASM 960
+ P ++ K+++
Sbjct: 1521 TLASTATTPGLSAKSTI 1537
Score = 70.5 bits (171), Expect = 1e-11
Identities = 205/1032 (19%), Positives = 341/1032 (33%), Gaps = 165/1032 (15%)
Query: 233 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292
T K +TP+ + + G E S S EE+ A+ + A A T+
Sbjct: 24 THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA---TT 80
Query: 293 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 352
+ A S P S G + P +G A G + S E+S + +P ++
Sbjct: 81 VLPAGSTP---SVLVGDSTPSPISSGSMETTALPGSTTKPGLS--EKSTTFYSSP-RSPD 134
Query: 353 SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREAL 412
+ P +S ++ES + P T + G +E + S S +D
Sbjct: 135 TTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLS 194
Query: 413 AAMNAAQV----------KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 462
A +P + P +T G L + + PV P T + G
Sbjct: 195 PGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLL-EASMPVHSSTRSPHTTLSPAG 253
Query: 463 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS--SPAKGPPQKAGPVAV 520
ES++ S SS PA + ++ TS SP+ P ++
Sbjct: 254 STTRQGESTTFHSWPSSKD-----TRPAPPTTTSAFVEPSTTSHGSPSSIPTTH---ISA 305
Query: 521 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 580
+ ++ S + S S + P + T + ++ ++TT + A
Sbjct: 306 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGE-------ESTTSHSSTTHTISSA 358
Query: 581 PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKS 640
P +SP ++ + + S S S S ++ TG V A+S
Sbjct: 359 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL--PARS 416
Query: 641 VGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAAS 700
L ++ + P+ + TA LPG T T +E+ SS + + AS
Sbjct: 417 TTSVLLGESTTSPISSGSMETTA--LPGST---TTPGLSERSTTFHSSPRSPATTLSPAS 471
Query: 701 PAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNS 760
S + T +++ P + + + + PG ++S
Sbjct: 472 TTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL----------------------SRHS 509
Query: 761 TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR 820
T P S + + A+ +GP ++S +S S S + A + P T
Sbjct: 510 TTSHSSPGSTDTT---LLPASTTTSGPSQESTTSHSSSGSTDTA-----LSPGSTT---- 557
Query: 821 AALAPAKESPRKGAAPT-------PPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVT 873
AL+ +ES + P P T +A + S + S + +PA+ T
Sbjct: 558 -ALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL---SPASST 613
Query: 874 SAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPAT 933
S + F PA TP+ A+ P EST S S PA+
Sbjct: 614 SPGLQGESTAF---QTHPASTHTTPSPPSTATAP----VEESTTYHRSPGSTPTTHFPAS 666
Query: 934 QCLTPGIRTNVV--TMPTAHPRIAPKA-SMAGASSSKESSRISDGKKQ------------ 978
+ + + + P A A S +SRIS G +
Sbjct: 667 STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG 726
Query: 979 --EGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSG---VDSAVGTLPAT 1033
E T S + L+ A++ L +R+QP S V A T P
Sbjct: 727 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST---TSRSQPGSTHSTVSPASTTTPGL 783
Query: 1034 SPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAH 1093
S +ST+V + P S+ +S EE S H
Sbjct: 784 SEESTTVYSSSRGSTETTVFPH----------------STTTSVHGEEPTTFHSRPASTH 827
Query: 1094 TLVGPTPSRTETLVEE-------------------TAAESSEDDVVAPSQSLLSG-YMTP 1133
T + S T L EE T A+ E+ PS S +G ++P
Sbjct: 828 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSP 887
Query: 1134 GLTPANSQASKATP-KLDSSPSVSSTLAAKDDPDGKQE------AKPQQAAGMLSPKTGG 1186
+ + ++TP +L S + ++TL E P+ LSP T
Sbjct: 888 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPAT-- 945
Query: 1187 KEAASGTTPQKS 1198
+SG + + S
Sbjct: 946 -TTSSGVSEESS 956
Score = 67.4 bits (163), Expect = 9e-11
Identities = 159/770 (20%), Positives = 264/770 (34%), Gaps = 83/770 (10%)
Query: 568 PKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG----SSPAVAGGTQRPAEDSSSSEESD 623
P+ + T+ ++ + G+ K+ T ++ A S + G T+ SS+
Sbjct: 4 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63
Query: 624 SEEEKTG------LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 677
SEE K +A TV A S L + P+ + TA LPG T
Sbjct: 64 SEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTA--LPGST---TKPG 118
Query: 678 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 737
+EK SS D+ AS S + T + + P + + G+ + PG ++
Sbjct: 119 LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG--LS 176
Query: 738 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 797
+ A SP + +P ++T + GP + +T SG E
Sbjct: 177 QESTASHSSPGPTDTTL-SPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE-- 233
Query: 798 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT----PPGKTGPSAAQAGKQD 853
A + T L+PA + R+G + T P K A
Sbjct: 234 ----------ASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA 283
Query: 854 DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARAS 913
S+ S P SA+ L+ + + P +T S R
Sbjct: 284 FVEPSTTSHGSPSSIPTTHISARSTTSGLV-EESTTYHSSPGSTQTMHFPESDTTSGRGE 342
Query: 914 ESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 973
EST SS+ T P + +V PT++ +P ++ A++ S +
Sbjct: 343 ESTTSHSSTTH--------TISSAPSTTSALVEEPTSY-HSSPGST---ATTHFPDSSTT 390
Query: 974 DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPAT 1033
G+ +E A+ S+ ++ L + + S P + + ++ + + T P
Sbjct: 391 SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGL 449
Query: 1034 SPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS--GSEE-----DGEGP 1086
S +ST+ + P+ P + + SS SE+S+ S S GS D
Sbjct: 450 SERSTTFHSS-------PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT 502
Query: 1087 QGAKSAHTLVGPTPSRTETLV----EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQA 1142
G T +P T+T + T+ S E S ++PG T A S
Sbjct: 503 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFG 562
Query: 1143 SKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1202
++T + S +TL PD + +A+ + TG +P S P
Sbjct: 563 QESTTFHSNPGSTHTTLF----PDSTTSSGIVEASTRVHSSTGSPRTT--LSPASSTSPG 616
Query: 1203 KGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESS 1262
+ T ++ T P P + A + V+ T SS
Sbjct: 617 LQGESTAFQTHPASTHTT------PSPPSTA---TAPVEESTTYHRSPGSTPTTHFPASS 667
Query: 1263 RKGWESRKRKLSGDQPAAR--TPRSKKKKKLGAGEGGEASVSPEKTSTTS 1310
S K + P A TP S G GE + +SP T T+
Sbjct: 668 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 717
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 97.1 bits (240), Expect = 1e-19
Identities = 247/1296 (19%), Positives = 452/1296 (34%), Gaps = 145/1296 (11%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS-PRKSAEPSA 165
+T +S G++ + + + ++ T + + P P +T +SG S S
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE 74
Query: 166 NTTL---------VSETEEEGSVPAFGA--------AAKPGMVSAGQADSSSEDTSSS-- 206
NTT+ S E +V G+ + MVSA +++++ T+SS
Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSET 134
Query: 207 -------SDETDVEVKASEKILQVRAAS-APAKGTPGKGATPAPPGKAGAVASQTKAGKP 258
S+ T V SE A S A T G T + + T
Sbjct: 135 TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG--- 191
Query: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318
SE+++ ++ SE T + AS S+ AAS E+ + A G
Sbjct: 192 ---SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA-------G 241
Query: 319 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP---QVRAASAPAKE---SPRK 372
+ AG E + +S+E+S++ +K + + + AAS E +
Sbjct: 242 SETTVSTAG--SETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
G+ GP +V E + ++ S++ R + V G + A
Sbjct: 300 GSETTMASTIGPETTKVSTASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTA 356
Query: 433 STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQ 491
S MG +T S + S SE ++ S++G E T
Sbjct: 357 SIMGS---------------ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAP 547
E + +I ++ T++ +G A V + SE S+ +S + S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 548 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 607
T A K T +T T ++ + V T +T + ++ A
Sbjct: 462 ETTTVTTAGSETKTAYTTG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519
Query: 608 GTQRPAEDSSSSEES--------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSL 658
G++ + SE + + TGL T + S + A +
Sbjct: 520 GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 579
Query: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
G GT G T V E++ +S +DSE +AS +T+ T +
Sbjct: 580 GSGTTAA--STAGSETTTVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTT 635
Query: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GK 775
A+ S T+S T + + + +TV A G + S G
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGT 692
Query: 776 AVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 835
+ ++T +GS + +E T A + S +T + + +G+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSE 751
Query: 836 PTPPGKTGPSAAQAGKQDDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN 888
T TG A GS + + + G V++A K +F + N
Sbjct: 752 TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-N 809
Query: 889 RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 948
+ T ++ ST STA S ++ + + T T G T +
Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869
Query: 949 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKA 1007
++ + + A S+ ++ ++G + +T+ S+ AS ++ + +
Sbjct: 870 SS------ETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
+ A + T +S S + T+ T ++ +V A+G+ + + T A S+
Sbjct: 924 TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STA 979
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETAAESSEDDVVA 1121
SE ++ S++GSE +G+++ T V T S T T+ T+ E SE V
Sbjct: 980 GSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037
Query: 1122 PSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
+ S + Y T T S T + ++ S ++T + D + +G
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTT 1094
Query: 1181 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1240
+ T G E + S+ +A+T++ S+ T + + +
Sbjct: 1095 TASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------TTASTTGSEMT 1144
Query: 1241 KVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEA 1299
V T + E + + SS G E+ G + + E A
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS--------TAGSETTTA 1196
Query: 1300 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1335
S + +T+T S ++ + A E S GS+
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1232
Score = 81.6 bits (200), Expect = 5e-15
Identities = 218/1160 (18%), Positives = 393/1160 (33%), Gaps = 158/1160 (13%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE---------------- 312
Query: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
+++ +++SS+ T V SE I AS T T + A + S+
Sbjct: 313 ------TTKVSTASSEVTTVFAAGSETI----RASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
T DS + SE ++ S E + A + + S G+ + + +
Sbjct: 363 TST-----DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417
Query: 313 PPGKTGPAVAKA--QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
G AV+ + + + S S+ E + + V A + K +
Sbjct: 418 TEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAY 477
Query: 371 RKGAAPAPPRKTGPAAAQV-QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
G+ TG V +G D+ ++S E S+ A++A + + +
Sbjct: 478 TTGSETTTASNTGLETTTVFTIG---SDTTTASTEG-SETTAVSATGSEMTTVSTEGSEN 533
Query: 430 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
ST G V + T S + + S + +E ++DS++G TA +
Sbjct: 534 TTVST-----TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
A ++ T S A A +E ++ SE ++ S S E A
Sbjct: 589 AGSET--------TTVSTA----DSENTTASTADSETTSASTTGSETTTASTTSSETTTA 636
Query: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
T + + T + +TT S + G++ T S GS V+
Sbjct: 637 ST--EGSETTTVSTTDSETTMVSTTGSERTITSTEGSET-----TTVSATGSETTVS--- 686
Query: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG-KGLQVKAASVPVKGSLGQGTAPVLPG 668
E S ++ S + E T ++ T + + +G ++ AS+
Sbjct: 687 ---TEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI---------------- 727
Query: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
TG T E E + +S E SE +AS +T+ T + A+ S
Sbjct: 728 -TGSETTTASTEGSETTTASTE--GSETTSASTTGSETTTASTTSSETTMASIMGSETTM 784
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
S G T + A + + V + T +A AS + + A ++T P
Sbjct: 785 ASTIGSETTKVSTASSKMTT-----VFTENSETTIASTTASETT----TVSTAGSETIPA 835
Query: 789 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 848
+GS + S E +ET +T + ES A T +T ++ +
Sbjct: 836 STAGSETTTTTSTEGSETTTASTEGSET------TTASTESSETTTATTIGSETTTASTE 889
Query: 849 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908
+ + + E+ + + +T+ S G T A + + T
Sbjct: 890 GSETTTTSTEGSETTTASTEGSEITTV--------------STTGSETTTASTEGSETTT 935
Query: 909 KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE 968
+ S++ SE V G T VT + A A + S
Sbjct: 936 ASTEGSELTTVSTTGSETITV------SAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989
Query: 969 SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1028
S + + T VS + ++ + ++ T S +AV
Sbjct: 990 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE--TTAVY 1047
Query: 1029 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
T T ++T+ +G+ + + S+ D E ++ S+SGS G
Sbjct: 1048 T---TGSETTTTSTEGS----ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 1089 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG---LTPANSQASKA 1145
+++ T V T S+T T + E SE V+ + S + T G T + +
Sbjct: 1101 SET--TTVYITGSKTTT----ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154
Query: 1146 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGA 1205
T S + +S+ A + E A T G E + +T G+
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTA-----STAGSETTTAST--------AGS 1201
Query: 1206 GNPQASTLALQSNITQCLLG 1225
AST ++N T C G
Sbjct: 1202 ETTTASTSGSETN-TACTTG 1220
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/802 (19%), Positives = 262/802 (32%), Gaps = 73/802 (9%)
Query: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 621
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 622 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 681
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 742 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 793
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 794 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 839
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 840 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 899
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 959
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 960 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1019
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1020 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1078
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1079 SEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1138
SE +G S +T V T S T T V T E++ + +S T T
Sbjct: 521 SEMTTVSTEG--SENTTVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTT 575
Query: 1139 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1198
+S T ++ S ++T++ D + + S T G E + +T
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSE 632
Query: 1199 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1258
G+ + S T + +T E V T
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATG 680
Query: 1259 KES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGK 1313
E+ S +G + ++G + + + + + EG E AS++ +T+T S
Sbjct: 681 SETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG 739
Query: 1314 AKRDKASGDVKEKKGKGSLGSQ 1335
++ AS + E + GS+
Sbjct: 740 SETTTASTEGSETTSASTTGSE 761
Score = 30.8 bits (68), Expect = 9.6
Identities = 40/233 (17%), Positives = 80/233 (34%), Gaps = 7/233 (3%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
+T+ S+E E T + AST S + + +++ E T + T +S
Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEM-TTVFTTVSETTTVSTIGSEATTSS---- 1167
Query: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
A G + S +A + + T + T + A + ++ +++S+
Sbjct: 1168 AAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPS 1227
Query: 203 TSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDS 262
++ S T + + I + A G T +GA A+ T
Sbjct: 1228 SAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVL 1287
Query: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
+++ S TP + + + T+ AP + A+ PG
Sbjct: 1288 TKATDVSIQPITNTPMSGT--RTTGTRLTASSSVTMAPGMDFTASAASHTVPG 1338
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 97.1 bits (240), Expect = 1e-19
Identities = 247/1296 (19%), Positives = 452/1296 (34%), Gaps = 145/1296 (11%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS-PRKSAEPSA 165
+T +S G++ + + + ++ T + + P P +T +SG S S
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE 74
Query: 166 NTTL---------VSETEEEGSVPAFGA--------AAKPGMVSAGQADSSSEDTSSS-- 206
NTT+ S E +V G+ + MVSA +++++ T+SS
Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSET 134
Query: 207 -------SDETDVEVKASEKILQVRAAS-APAKGTPGKGATPAPPGKAGAVASQTKAGKP 258
S+ T V SE A S A T G T + + T
Sbjct: 135 TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG--- 191
Query: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318
SE+++ ++ SE T + AS S+ AAS E+ + A G
Sbjct: 192 ---SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA-------G 241
Query: 319 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP---QVRAASAPAKE---SPRK 372
+ AG E + +S+E+S++ +K + + + AAS E +
Sbjct: 242 SETTVSTAG--SETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
G+ GP +V E + ++ S++ R + V G + A
Sbjct: 300 GSETTMASTIGPETTKVSTASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTA 356
Query: 433 STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQ 491
S MG +T S + S SE ++ S++G E T
Sbjct: 357 SIMGS---------------ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAP 547
E + +I ++ T++ +G A V + SE S+ +S + S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 548 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 607
T A K T +T T ++ + V T +T + ++ A
Sbjct: 462 ETTTVTTAGSETKTAYTTG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519
Query: 608 GTQRPAEDSSSSEES--------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSL 658
G++ + SE + + TGL T + S + A +
Sbjct: 520 GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 579
Query: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
G GT G T V E++ +S +DSE +AS +T+ T +
Sbjct: 580 GSGTTAA--STAGSETTTVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTT 635
Query: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GK 775
A+ S T+S T + + + +TV A G + S G
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGT 692
Query: 776 AVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 835
+ ++T +GS + +E T A + S +T + + +G+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSE 751
Query: 836 PTPPGKTGPSAAQAGKQDDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN 888
T TG A GS + + + G V++A K +F + N
Sbjct: 752 TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-N 809
Query: 889 RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 948
+ T ++ ST STA S ++ + + T T G T +
Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869
Query: 949 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKA 1007
++ + + A S+ ++ ++G + +T+ S+ AS ++ + +
Sbjct: 870 SS------ETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
+ A + T +S S + T+ T ++ +V A+G+ + + T A S+
Sbjct: 924 TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STA 979
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETAAESSEDDVVA 1121
SE ++ S++GSE +G+++ T V T S T T+ T+ E SE V
Sbjct: 980 GSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037
Query: 1122 PSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
+ S + Y T T S T + ++ S ++T + D + +G
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTT 1094
Query: 1181 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1240
+ T G E + S+ +A+T++ S+ T + + +
Sbjct: 1095 TASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------TTASTTGSEMT 1144
Query: 1241 KVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEA 1299
V T + E + + SS G E+ G + + E A
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS--------TAGSETTTA 1196
Query: 1300 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1335
S + +T+T S ++ + A E S GS+
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1232
Score = 81.6 bits (200), Expect = 5e-15
Identities = 218/1160 (18%), Positives = 393/1160 (33%), Gaps = 158/1160 (13%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE---------------- 312
Query: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
+++ +++SS+ T V SE I AS T T + A + S+
Sbjct: 313 ------TTKVSTASSEVTTVFAAGSETI----RASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
T DS + SE ++ S E + A + + S G+ + + +
Sbjct: 363 TST-----DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417
Query: 313 PPGKTGPAVAKA--QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
G AV+ + + + S S+ E + + V A + K +
Sbjct: 418 TEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAY 477
Query: 371 RKGAAPAPPRKTGPAAAQV-QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
G+ TG V +G D+ ++S E S+ A++A + + +
Sbjct: 478 TTGSETTTASNTGLETTTVFTIG---SDTTTASTEG-SETTAVSATGSEMTTVSTEGSEN 533
Query: 430 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
ST G V + T S + + S + +E ++DS++G TA +
Sbjct: 534 TTVST-----TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
A ++ T S A A +E ++ SE ++ S S E A
Sbjct: 589 AGSET--------TTVSTA----DSENTTASTADSETTSASTTGSETTTASTTSSETTTA 636
Query: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
T + + T + +TT S + G++ T S GS V+
Sbjct: 637 ST--EGSETTTVSTTDSETTMVSTTGSERTITSTEGSET-----TTVSATGSETTVS--- 686
Query: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG-KGLQVKAASVPVKGSLGQGTAPVLPG 668
E S ++ S + E T ++ T + + +G ++ AS+
Sbjct: 687 ---TEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI---------------- 727
Query: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
TG T E E + +S E SE +AS +T+ T + A+ S
Sbjct: 728 -TGSETTTASTEGSETTTASTE--GSETTSASTTGSETTTASTTSSETTMASIMGSETTM 784
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
S G T + A + + V + T +A AS + + A ++T P
Sbjct: 785 ASTIGSETTKVSTASSKMTT-----VFTENSETTIASTTASETT----TVSTAGSETIPA 835
Query: 789 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 848
+GS + S E +ET +T + ES A T +T ++ +
Sbjct: 836 STAGSETTTTTSTEGSETTTASTEGSET------TTASTESSETTTATTIGSETTTASTE 889
Query: 849 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908
+ + + E+ + + +T+ S G T A + + T
Sbjct: 890 GSETTTTSTEGSETTTASTEGSEITTV--------------STTGSETTTASTEGSETTT 935
Query: 909 KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE 968
+ S++ SE V G T VT + A A + S
Sbjct: 936 ASTEGSELTTVSTTGSETITV------SAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989
Query: 969 SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1028
S + + T VS + ++ + ++ T S +AV
Sbjct: 990 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE--TTAVY 1047
Query: 1029 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
T T ++T+ +G+ + + S+ D E ++ S+SGS G
Sbjct: 1048 T---TGSETTTTSTEGS----ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 1089 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG---LTPANSQASKA 1145
+++ T V T S+T T + E SE V+ + S + T G T + +
Sbjct: 1101 SET--TTVYITGSKTTT----ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154
Query: 1146 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGA 1205
T S + +S+ A + E A T G E + +T G+
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTA-----STAGSETTTAST--------AGS 1201
Query: 1206 GNPQASTLALQSNITQCLLG 1225
AST ++N T C G
Sbjct: 1202 ETTTASTSGSETN-TACTTG 1220
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/802 (19%), Positives = 262/802 (32%), Gaps = 73/802 (9%)
Query: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 621
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 622 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 681
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 742 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 793
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 794 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 839
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 840 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 899
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 959
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 960 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1019
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1020 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1078
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1079 SEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1138
SE +G S +T V T S T T V T E++ + +S T T
Sbjct: 521 SEMTTVSTEG--SENTTVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTT 575
Query: 1139 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1198
+S T ++ S ++T++ D + + S T G E + +T
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSE 632
Query: 1199 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1258
G+ + S T + +T E V T
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATG 680
Query: 1259 KES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGK 1313
E+ S +G + ++G + + + + + EG E AS++ +T+T S
Sbjct: 681 SETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG 739
Query: 1314 AKRDKASGDVKEKKGKGSLGSQ 1335
++ AS + E + GS+
Sbjct: 740 SETTTASTEGSETTSASTTGSE 761
Score = 31.2 bits (69), Expect = 7.4
Identities = 40/233 (17%), Positives = 80/233 (34%), Gaps = 7/233 (3%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
+T+ S+E E T + AST S + + +++ E T + T +S
Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEM-TTVFTTVSETTTVSTIGSEATTSS---- 1167
Query: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
A G + S +A + + T + T + A + ++ +++S+
Sbjct: 1168 AAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPS 1227
Query: 203 TSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDS 262
++ S T + + I + A G T +GA A+ T
Sbjct: 1228 SAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVL 1287
Query: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
+++ S TP + + + T+ AP + A+ PG
Sbjct: 1288 TKATDVSIQPITNTPMSGT--RTTGTRLTASSSVTMAPGMDFTASAASHTVPG 1338
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 97.1 bits (240), Expect = 1e-19
Identities = 247/1296 (19%), Positives = 452/1296 (34%), Gaps = 145/1296 (11%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS-PRKSAEPSA 165
+T +S G++ + + + ++ T + + P P +T +SG S S
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE 74
Query: 166 NTTL---------VSETEEEGSVPAFGA--------AAKPGMVSAGQADSSSEDTSSS-- 206
NTT+ S E +V G+ + MVSA +++++ T+SS
Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSET 134
Query: 207 -------SDETDVEVKASEKILQVRAAS-APAKGTPGKGATPAPPGKAGAVASQTKAGKP 258
S+ T V SE A S A T G T + + T
Sbjct: 135 TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG--- 191
Query: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318
SE+++ ++ SE T + AS S+ AAS E+ + A G
Sbjct: 192 ---SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA-------G 241
Query: 319 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP---QVRAASAPAKE---SPRK 372
+ AG E + +S+E+S++ +K + + + AAS E +
Sbjct: 242 SETTVSTAG--SETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
G+ GP +V E + ++ S++ R + V G + A
Sbjct: 300 GSETTMASTIGPETTKVSTASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTA 356
Query: 433 STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQ 491
S MG +T S + S SE ++ S++G E T
Sbjct: 357 SIMGS---------------ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAP 547
E + +I ++ T++ +G A V + SE S+ +S + S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 548 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 607
T A K T +T T ++ + V T +T + ++ A
Sbjct: 462 ETTTVTTAGSETKTAYTTG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519
Query: 608 GTQRPAEDSSSSEES--------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSL 658
G++ + SE + + TGL T + S + A +
Sbjct: 520 GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 579
Query: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
G GT G T V E++ +S +DSE +AS +T+ T +
Sbjct: 580 GSGTTAA--STAGSETTTVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTT 635
Query: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GK 775
A+ S T+S T + + + +TV A G + S G
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGT 692
Query: 776 AVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 835
+ ++T +GS + +E T A + S +T + + +G+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSE 751
Query: 836 PTPPGKTGPSAAQAGKQDDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN 888
T TG A GS + + + G V++A K +F + N
Sbjct: 752 TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-N 809
Query: 889 RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 948
+ T ++ ST STA S ++ + + T T G T +
Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869
Query: 949 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKA 1007
++ + + A S+ ++ ++G + +T+ S+ AS ++ + +
Sbjct: 870 SS------ETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
+ A + T +S S + T+ T ++ +V A+G+ + + T A S+
Sbjct: 924 TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STA 979
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETAAESSEDDVVA 1121
SE ++ S++GSE +G+++ T V T S T T+ T+ E SE V
Sbjct: 980 GSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037
Query: 1122 PSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
+ S + Y T T S T + ++ S ++T + D + +G
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTT 1094
Query: 1181 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1240
+ T G E + S+ +A+T++ S+ T + + +
Sbjct: 1095 TASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------TTASTTGSEMT 1144
Query: 1241 KVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEA 1299
V T + E + + SS G E+ G + + E A
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS--------TAGSETTTA 1196
Query: 1300 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1335
S + +T+T S ++ + A E S GS+
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1232
Score = 81.6 bits (200), Expect = 5e-15
Identities = 218/1160 (18%), Positives = 393/1160 (33%), Gaps = 158/1160 (13%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE---------------- 312
Query: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
+++ +++SS+ T V SE I AS T T + A + S+
Sbjct: 313 ------TTKVSTASSEVTTVFAAGSETI----RASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
T DS + SE ++ S E + A + + S G+ + + +
Sbjct: 363 TST-----DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417
Query: 313 PPGKTGPAVAKA--QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
G AV+ + + + S S+ E + + V A + K +
Sbjct: 418 TEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAY 477
Query: 371 RKGAAPAPPRKTGPAAAQV-QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
G+ TG V +G D+ ++S E S+ A++A + + +
Sbjct: 478 TTGSETTTASNTGLETTTVFTIG---SDTTTASTEG-SETTAVSATGSEMTTVSTEGSEN 533
Query: 430 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
ST G V + T S + + S + +E ++DS++G TA +
Sbjct: 534 TTVST-----TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
A ++ T S A A +E ++ SE ++ S S E A
Sbjct: 589 AGSET--------TTVSTA----DSENTTASTADSETTSASTTGSETTTASTTSSETTTA 636
Query: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
T + + T + +TT S + G++ T S GS V+
Sbjct: 637 ST--EGSETTTVSTTDSETTMVSTTGSERTITSTEGSET-----TTVSATGSETTVS--- 686
Query: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG-KGLQVKAASVPVKGSLGQGTAPVLPG 668
E S ++ S + E T ++ T + + +G ++ AS+
Sbjct: 687 ---TEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI---------------- 727
Query: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
TG T E E + +S E SE +AS +T+ T + A+ S
Sbjct: 728 -TGSETTTASTEGSETTTASTE--GSETTSASTTGSETTTASTTSSETTMASIMGSETTM 784
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
S G T + A + + V + T +A AS + + A ++T P
Sbjct: 785 ASTIGSETTKVSTASSKMTT-----VFTENSETTIASTTASETT----TVSTAGSETIPA 835
Query: 789 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 848
+GS + S E +ET +T + ES A T +T ++ +
Sbjct: 836 STAGSETTTTTSTEGSETTTASTEGSET------TTASTESSETTTATTIGSETTTASTE 889
Query: 849 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908
+ + + E+ + + +T+ S G T A + + T
Sbjct: 890 GSETTTTSTEGSETTTASTEGSEITTV--------------STTGSETTTASTEGSETTT 935
Query: 909 KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE 968
+ S++ SE V G T VT + A A + S
Sbjct: 936 ASTEGSELTTVSTTGSETITV------SAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989
Query: 969 SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1028
S + + T VS + ++ + ++ T S +AV
Sbjct: 990 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE--TTAVY 1047
Query: 1029 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
T T ++T+ +G+ + + S+ D E ++ S+SGS G
Sbjct: 1048 T---TGSETTTTSTEGS----ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 1089 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG---LTPANSQASKA 1145
+++ T V T S+T T + E SE V+ + S + T G T + +
Sbjct: 1101 SET--TTVYITGSKTTT----ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154
Query: 1146 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGA 1205
T S + +S+ A + E A T G E + +T G+
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTA-----STAGSETTTAST--------AGS 1201
Query: 1206 GNPQASTLALQSNITQCLLG 1225
AST ++N T C G
Sbjct: 1202 ETTTASTSGSETN-TACTTG 1220
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/802 (19%), Positives = 262/802 (32%), Gaps = 73/802 (9%)
Query: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 621
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 622 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 681
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 742 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 793
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 794 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 839
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 840 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 899
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 959
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 960 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1019
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1020 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1078
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1079 SEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1138
SE +G S +T V T S T T V T E++ + +S T T
Sbjct: 521 SEMTTVSTEG--SENTTVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTT 575
Query: 1139 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1198
+S T ++ S ++T++ D + + S T G E + +T
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSE 632
Query: 1199 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1258
G+ + S T + +T E V T
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATG 680
Query: 1259 KES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGK 1313
E+ S +G + ++G + + + + + EG E AS++ +T+T S
Sbjct: 681 SETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG 739
Query: 1314 AKRDKASGDVKEKKGKGSLGSQ 1335
++ AS + E + GS+
Sbjct: 740 SETTTASTEGSETTSASTTGSE 761
Score = 31.2 bits (69), Expect = 7.4
Identities = 40/233 (17%), Positives = 80/233 (34%), Gaps = 7/233 (3%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
+T+ S+E E T + AST S + + +++ E T + T +S
Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEM-TTVFTTVSETTTVSTIGSEATTSS---- 1167
Query: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
A G + S +A + + T + T + A + ++ +++S+
Sbjct: 1168 AAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPS 1227
Query: 203 TSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDS 262
++ S T + + I + A G T +GA A+ T
Sbjct: 1228 SAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVL 1287
Query: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
+++ S TP + + + T+ AP + A+ PG
Sbjct: 1288 TKATDVSIQPITNTPMSGT--RTTGTRPTASSSVTMAPGMDFTASAASHTVPG 1338
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 97.1 bits (240), Expect = 1e-19
Identities = 247/1296 (19%), Positives = 452/1296 (34%), Gaps = 145/1296 (11%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS-PRKSAEPSA 165
+T +S G++ + + + ++ T + + P P +T +SG S S
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE 74
Query: 166 NTTL---------VSETEEEGSVPAFGA--------AAKPGMVSAGQADSSSEDTSSS-- 206
NTT+ S E +V G+ + MVSA +++++ T+SS
Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSET 134
Query: 207 -------SDETDVEVKASEKILQVRAAS-APAKGTPGKGATPAPPGKAGAVASQTKAGKP 258
S+ T V SE A S A T G T + + T
Sbjct: 135 TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG--- 191
Query: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318
SE+++ ++ SE T + AS S+ AAS E+ + A G
Sbjct: 192 ---SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA-------G 241
Query: 319 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP---QVRAASAPAKE---SPRK 372
+ AG E + +S+E+S++ +K + + + AAS E +
Sbjct: 242 SETTVSTAG--SETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299
Query: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 432
G+ GP +V E + ++ S++ R + V G + A
Sbjct: 300 GSETTMASTIGPETTKVSTASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTA 356
Query: 433 STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQ 491
S MG +T S + S SE ++ S++G E T
Sbjct: 357 SIMGS---------------ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAP 547
E + +I ++ T++ +G A V + SE S+ +S + S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 548 AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 607
T A K T +T T ++ + V T +T + ++ A
Sbjct: 462 ETTTVTTAGSETKTAYTTG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519
Query: 608 GTQRPAEDSSSSEES--------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSL 658
G++ + SE + + TGL T + S + A +
Sbjct: 520 GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 579
Query: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
G GT G T V E++ +S +DSE +AS +T+ T +
Sbjct: 580 GSGTTAA--STAGSETTTVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTT 635
Query: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GK 775
A+ S T+S T + + + +TV A G + S G
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGT 692
Query: 776 AVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 835
+ ++T +GS + +E T A + S +T + + +G+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSE 751
Query: 836 PTPPGKTGPSAAQAGKQDDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN 888
T TG A GS + + + G V++A K +F + N
Sbjct: 752 TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-N 809
Query: 889 RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 948
+ T ++ ST STA S ++ + + T T G T +
Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869
Query: 949 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKA 1007
++ + + A S+ ++ ++G + +T+ S+ AS ++ + +
Sbjct: 870 SS------ETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923
Query: 1008 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1067
+ A + T +S S + T+ T ++ +V A+G+ + + T A S+
Sbjct: 924 TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STA 979
Query: 1068 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETAAESSEDDVVA 1121
SE ++ S++GSE +G+++ T V T S T T+ T+ E SE V
Sbjct: 980 GSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037
Query: 1122 PSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
+ S + Y T T S T + ++ S ++T + D + +G
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTT 1094
Query: 1181 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1240
+ T G E + S+ +A+T++ S+ T + + +
Sbjct: 1095 TASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------TTASTTGSEMT 1144
Query: 1241 KVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEA 1299
V T + E + + SS G E+ G + + E A
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS--------TAGSETTTA 1196
Query: 1300 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1335
S + +T+T S ++ + A E S GS+
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1232
Score = 81.6 bits (200), Expect = 5e-15
Identities = 218/1160 (18%), Positives = 393/1160 (33%), Gaps = 158/1160 (13%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE---------------- 312
Query: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
+++ +++SS+ T V SE I AS T T + A + S+
Sbjct: 313 ------TTKVSTASSEVTTVFAAGSETI----RASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
T DS + SE ++ S E + A + + S G+ + + +
Sbjct: 363 TST-----DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417
Query: 313 PPGKTGPAVAKA--QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 370
G AV+ + + + S S+ E + + V A + K +
Sbjct: 418 TEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAY 477
Query: 371 RKGAAPAPPRKTGPAAAQV-QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
G+ TG V +G D+ ++S E S+ A++A + + +
Sbjct: 478 TTGSETTTASNTGLETTTVFTIG---SDTTTASTEG-SETTAVSATGSEMTTVSTEGSEN 533
Query: 430 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
ST G V + T S + + S + +E ++DS++G TA +
Sbjct: 534 TTVST-----TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588
Query: 490 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 549
A ++ T S A A +E ++ SE ++ S S E A
Sbjct: 589 AGSET--------TTVSTA----DSENTTASTADSETTSASTTGSETTTASTTSSETTTA 636
Query: 550 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
T + + T + +TT S + G++ T S GS V+
Sbjct: 637 ST--EGSETTTVSTTDSETTMVSTTGSERTITSTEGSET-----TTVSATGSETTVS--- 686
Query: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG-KGLQVKAASVPVKGSLGQGTAPVLPG 668
E S ++ S + E T ++ T + + +G ++ AS+
Sbjct: 687 ---TEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI---------------- 727
Query: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
TG T E E + +S E SE +AS +T+ T + A+ S
Sbjct: 728 -TGSETTTASTEGSETTTASTE--GSETTSASTTGSETTTASTTSSETTMASIMGSETTM 784
Query: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
S G T + A + + V + T +A AS + + A ++T P
Sbjct: 785 ASTIGSETTKVSTASSKMTT-----VFTENSETTIASTTASETT----TVSTAGSETIPA 835
Query: 789 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 848
+GS + S E +ET +T + ES A T +T ++ +
Sbjct: 836 STAGSETTTTTSTEGSETTTASTEGSET------TTASTESSETTTATTIGSETTTASTE 889
Query: 849 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908
+ + + E+ + + +T+ S G T A + + T
Sbjct: 890 GSETTTTSTEGSETTTASTEGSEITTV--------------STTGSETTTASTEGSETTT 935
Query: 909 KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE 968
+ S++ SE V G T VT + A A + S
Sbjct: 936 ASTEGSELTTVSTTGSETITV------SAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989
Query: 969 SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1028
S + + T VS + ++ + ++ T S +AV
Sbjct: 990 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE--TTAVY 1047
Query: 1029 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
T T ++T+ +G+ + + S+ D E ++ S+SGS G
Sbjct: 1048 T---TGSETTTTSTEGS----ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAG 1100
Query: 1089 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG---LTPANSQASKA 1145
+++ T V T S+T T + E SE V+ + S + T G T + +
Sbjct: 1101 SET--TTVYITGSKTTT----ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154
Query: 1146 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGA 1205
T S + +S+ A + E A T G E + +T G+
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTA-----STAGSETTTAST--------AGS 1201
Query: 1206 GNPQASTLALQSNITQCLLG 1225
AST ++N T C G
Sbjct: 1202 ETTTASTSGSETN-TACTTG 1220
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/802 (19%), Positives = 262/802 (32%), Gaps = 73/802 (9%)
Query: 563 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 621
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 622 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 681
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 682 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 741
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 742 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 793
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 794 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 839
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 840 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 899
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 959
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 960 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1019
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1020 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1078
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1079 SEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1138
SE +G S +T V T S T T V T E++ + +S T T
Sbjct: 521 SEMTTVSTEG--SENTTVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTT 575
Query: 1139 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1198
+S T ++ S ++T++ D + + S T G E + +T
Sbjct: 576 DSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSE 632
Query: 1199 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1258
G+ + S T + +T E V T
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATG 680
Query: 1259 KES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGK 1313
E+ S +G + ++G + + + + + EG E AS++ +T+T S
Sbjct: 681 SETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG 739
Query: 1314 AKRDKASGDVKEKKGKGSLGSQ 1335
++ AS + E + GS+
Sbjct: 740 SETTTASTEGSETTSASTTGSE 761
Score = 31.2 bits (69), Expect = 7.4
Identities = 40/233 (17%), Positives = 80/233 (34%), Gaps = 7/233 (3%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
+T+ S+E E T + AST S + + +++ E T + T +S
Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEM-TTVFTTVSETTTVSTIGSEATTSS---- 1167
Query: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
A G + S +A + + T + T + A + ++ +++S+
Sbjct: 1168 AAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPS 1227
Query: 203 TSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDS 262
++ S T + + I + A G T +GA A+ T
Sbjct: 1228 SAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVL 1287
Query: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
+++ S TP + + + T+ AP + A+ PG
Sbjct: 1288 TKATDVSIQPITNTPMSGT--RTTGTRPTASSSVTMAPGMDFTASAASHTVPG 1338
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.296 0.114 0.299
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,128,223
Number of Sequences: 37866
Number of extensions: 3448111
Number of successful extensions: 61674
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 718
Number of HSP's successfully gapped in prelim test: 2542
Number of HSP's that attempted gapping in prelim test: 21069
Number of HSP's gapped (non-prelim): 23584
length of query: 1412
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1297
effective length of database: 13,892,928
effective search space: 18019127616
effective search space used: 18019127616
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.