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Search of human proteins with 207113160
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform
d [Homo sapiens]
(1488 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 2852 0.0
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 2762 0.0
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 2758 0.0
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 2470 0.0
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 2466 0.0
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 1822 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 155 2e-37
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 149 3e-35
gi|150170670 piccolo isoform 2 [Homo sapiens] 124 5e-28
gi|150378539 piccolo isoform 1 [Homo sapiens] 124 5e-28
gi|91982772 mucin 17 [Homo sapiens] 123 2e-27
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 122 3e-27
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 117 1e-25
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 117 1e-25
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 115 3e-25
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 114 5e-25
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 114 5e-25
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ... 109 2e-23
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 108 3e-23
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 105 4e-22
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 99 2e-20
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 98 5e-20
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 98 5e-20
gi|110832843 TBP-associated factor 4 [Homo sapiens] 96 3e-19
gi|167736355 mucin 4 isoform a [Homo sapiens] 96 3e-19
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 95 4e-19
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 95 4e-19
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 95 4e-19
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 95 4e-19
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 93 2e-18
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 2852 bits (7392), Expect = 0.0
Identities = 1488/1488 (100%), Positives = 1488/1488 (100%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
Query: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1140
AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1140
Query: 1141 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ 1200
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ
Sbjct: 1141 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ 1200
Query: 1201 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1260
SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT
Sbjct: 1201 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1260
Query: 1261 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1320
GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT
Sbjct: 1261 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1320
Query: 1321 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1380
ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE
Sbjct: 1321 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1380
Query: 1381 KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK 1440
KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK
Sbjct: 1381 KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK 1440
Query: 1441 EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1441 EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 2762 bits (7160), Expect = 0.0
Identities = 1450/1488 (97%), Positives = 1450/1488 (97%), Gaps = 38/1488 (2%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ------------------- 1061
Query: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1140
VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1062 -------------------VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
Query: 1141 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ 1200
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ
Sbjct: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ 1162
Query: 1201 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1260
SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT
Sbjct: 1163 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1222
Query: 1261 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1320
GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT
Sbjct: 1223 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1282
Query: 1321 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1380
ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE
Sbjct: 1283 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1342
Query: 1381 KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK 1440
KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK
Sbjct: 1343 KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK 1402
Query: 1441 EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1403 EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1450
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 2758 bits (7148), Expect = 0.0
Identities = 1450/1489 (97%), Positives = 1450/1489 (97%), Gaps = 39/1489 (2%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ------------------- 1061
Query: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1140
VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1062 -------------------VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
Query: 1141 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL-GPTPSRTETLVEETAAESSEDDVVAPS 1199
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL GPTPSRTETLVEETAAESSEDDVVAPS
Sbjct: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1162
Query: 1200 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1259
QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK
Sbjct: 1163 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1222
Query: 1260 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1319
TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL
Sbjct: 1223 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1282
Query: 1320 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1379
TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP
Sbjct: 1283 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1342
Query: 1380 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1439
EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK
Sbjct: 1343 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1402
Query: 1440 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1403 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1451
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 2470 bits (6402), Expect = 0.0
Identities = 1323/1488 (88%), Positives = 1345/1488 (90%), Gaps = 77/1488 (5%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEE
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEE----------------------------- 91
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
E+A+AET KA P T +++L P E + +ETE+ G
Sbjct: 92 --EEAEAETAKAT--------PRLASTNSSVLGADLPSSMKEKAK-----AETEKAGKT- 135
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
+S + + + GK K A+ A++ E+ + P
Sbjct: 136 ---------------GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
A G K G + + E+ S SS+E T +VKASEKILQV
Sbjct: 181 AFGAAA------KPGMVSAGQADSSSEDTSSSSDE-----------TDVEVKASEKILQV 223
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 224 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 343
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 344 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 404 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 463
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 464 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL
Sbjct: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
Query: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1140
AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
Query: 1141 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ 1200
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ
Sbjct: 1064 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQ 1123
Query: 1201 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1260
SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT
Sbjct: 1124 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1183
Query: 1261 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1320
GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT
Sbjct: 1184 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1243
Query: 1321 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1380
ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE
Sbjct: 1244 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1303
Query: 1381 KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK 1440
KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK
Sbjct: 1304 KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKK 1363
Query: 1441 EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1364 EKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1411
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 2466 bits (6390), Expect = 0.0
Identities = 1323/1489 (88%), Positives = 1345/1489 (90%), Gaps = 78/1489 (5%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEE
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEE----------------------------- 91
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
E+A+AET KA P T +++L P E + +ETE+ G
Sbjct: 92 --EEAEAETAKAT--------PRLASTNSSVLGADLPSSMKEKAK-----AETEKAGKT- 135
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
+S + + + GK K A+ A++ E+ + P
Sbjct: 136 ---------------GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
A G K G + + E+ S SS+E T +VKASEKILQV
Sbjct: 181 AFGAAA------KPGMVSAGQADSSSEDTSSSSDE-----------TDVEVKASEKILQV 223
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 224 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 343
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 344 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 404 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 463
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 464 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL
Sbjct: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
Query: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1140
AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
Query: 1141 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL-GPTPSRTETLVEETAAESSEDDVVAPS 1199
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL GPTPSRTETLVEETAAESSEDDVVAPS
Sbjct: 1064 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1123
Query: 1200 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1259
QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK
Sbjct: 1124 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1183
Query: 1260 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1319
TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL
Sbjct: 1184 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1243
Query: 1320 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1379
TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP
Sbjct: 1244 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1303
Query: 1380 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1439
EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK
Sbjct: 1304 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1363
Query: 1440 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1364 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 1822 bits (4719), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Score = 410 bits (1053), Expect = e-114
Identities = 355/1015 (34%), Positives = 457/1015 (45%), Gaps = 161/1015 (15%)
Query: 194 GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVK 253
G+ + ED + + +T V P SS +E+ A A P ++ V
Sbjct: 60 GRKRKAEEDAALQAKKTRVSD-----PISTSESSEEEEEAEAETAKATP-RLASTNSSVL 113
Query: 254 GGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV---KASEKILQVRAASAPAKGT 310
G LP + + K E ++ + G+ A T + + K+ K + A + T
Sbjct: 114 GADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
Query: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQ 370
+G+ PA A A AG+ ++SSSE++S S +ET ++ K S K +Q
Sbjct: 174 EEEGSVPA--FGAAAKPGMVSAGQ----ADSSSEDTSSSSDETD-----VEGKPSVKPAQ 222
Query: 371 VGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAG---------KREEDSQSSSEESDSEE 421
V A+S KESP + AAPAP GK G + + G K EE+S+SS E S+SEE
Sbjct: 223 VKASSVSTKESPARKAAPAP-GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE 281
Query: 422 EAPA----QAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS 477
EAPA Q K S K QVRAASAPAK +P KGA PAPP K G A+Q + GK EEDS S
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 478 SSEES-DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSA 536
SSEES DS+ E AA Q K GK+ QV AS KGA P PPGK GPA A
Sbjct: 342 SSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA 401
Query: 537 QVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK---------G 587
Q GK EEDS+SSSEES + APAQ K G Q + S+PAK
Sbjct: 402 QAGKREEDSQSSSEESDSEEE-------APAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
PP+K GP A QV+ K ++S SS E SDS EA AAM AAQ KP K PQ K
Sbjct: 455 PPRKTGPAAAQVQVGKQEEDSRSSSEESDS--DREALAAMNAAQVKPLGKSPQVKPASTM 512
Query: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707
PV P K G AT P+ G +SSS E SDS + +
Sbjct: 513 GMGPLGKGAGPV-----PPGKVGPAT------PSAQVGKWEEDSESSSEESSDSSDGEVP 561
Query: 708 LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED-SESSE 766
AV Q KS+G LQ K S P KG P K GP QVKAEK D SESSE
Sbjct: 562 TAVAPAQEKSLGNILQAKPTSSPAKGP---------PQKAGPVAVQVKAEKPMDNSESSE 612
Query: 767 EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSK 826
E SDS ++ +PA + + K K A T SA V QA +++ +
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 827 VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEE----AE 882
P +P AVA Q P EDS SSEE SDSEEE A
Sbjct: 673 TSPAGSSP------------------AVAGGTQR---PAEDSSSSEE-SDSEEEKTGLAV 710
Query: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ--AGKQDDSGSSSEESD 940
T+ Q K GK Q++AA P K S +G AP PGKTGP+ Q A KQ+DS SS EESD
Sbjct: 711 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD 770
Query: 941 SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
S+ EA AA+PAQ + + +A+A+ + AR+ S++
Sbjct: 771 SE-EA--------------------------AASPAQVKTSVKKTQAKANPAAARAPSAK 803
Query: 1001 SEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPAT 1060
PG VVT A + + S++ + +T
Sbjct: 804 GTIS---------APG---KVVTA-------------AAQAKQRSPSKVKPPVRNPQNST 838
Query: 1061 QVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQ-- 1118
V + PAS+P A+ AQ + + ++ S + TL P + Q
Sbjct: 839 -VLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR 897
Query: 1119 ---AKGTNKLRKPKLPEVQQAT-KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA 1169
A RK P T + + +DS SS S+ DGE P SA
Sbjct: 898 AALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSA 952
Score = 266 bits (681), Expect = 8e-71
Identities = 303/1001 (30%), Positives = 402/1001 (40%), Gaps = 171/1001 (17%)
Query: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
RK AA + D S+SE S+ + EA A A + + V A
Sbjct: 63 RKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMK 122
Query: 517 LGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNIL 576
A GK G + P GK + S + T V+ +E+
Sbjct: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG----- 177
Query: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
S PA G K G V A + +SE + SSD D E KP++
Sbjct: 178 -----SVPAFGAAAKPG----MVSAGQADSSSEDTSSSSDETDVE----------GKPSV 218
Query: 637 KIPQTKACPKKTNTTASAKVAPV--RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
K Q KA T + + K AP +VG P+ G A PA + ++P E+S
Sbjct: 219 KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA-------KKPEEESE 271
Query: 695 SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
SSEE SE E+ A T Q K+ K LQV+AAS P KG+ G+G P PGK G +Q
Sbjct: 272 SSEEG-SESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 330
Query: 755 KAEK-QEDSESSEEES-DSEE---AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
KA K +EDSESS EES DSEE AA + Q K S K +Q A A A+ KG AP
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 810 GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP-EEDS 868
P K P V A+AQ G EEDS
Sbjct: 391 --------------PGKTGPAV--------------------------AKAQAGKREEDS 410
Query: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QA 926
SS EESDSEEEA AQ KPSGK Q+RAA APAKESPRKGAAP PP KTGP+AA Q
Sbjct: 411 QSSSEESDSEEEAP--AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 468
Query: 927 GKQ-DDSGSSSEESDSDGEAPAAVTSAQV--------IKP-PLIFVDPNRSPAGPAATPA 976
GKQ +DS SSSEESDSD EA AA+ +AQV +KP + + P AGP P
Sbjct: 469 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP-VPPG 527
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP--- 1033
+ A+ + E + SSS ES D + P ++ + A P +P
Sbjct: 528 KVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG 587
Query: 1034 --------------KASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKV 1079
+ M + SS+ESS +D ++ T K +P T+A K
Sbjct: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
Query: 1080 LAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKA 1139
AS PV + + GT ATSP +S P V T+
Sbjct: 648 TNTTASAKVAPV---RVGTQAPRKAGT--ATSPAGSS--------------PAVAGGTQR 688
Query: 1140 PESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPS 1199
P ++DS S +S S E+ G A T+G S + L + A+ + + +
Sbjct: 689 P--AEDSSSSEESDSEEEKTG-------LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 739
Query: 1200 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA----AGM 1255
+L G P +T +A K S S AA K K QA A
Sbjct: 740 APVLPGKTGPTVTQV--KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 797
Query: 1256 LSPKTGGKEAASG-----TTPQKSRKPKK---GAGNPQASTLALQSNITQCLLGQPWPLN 1307
+P G +A G K R P K NPQ ST+ + +
Sbjct: 798 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPAS----------- 846
Query: 1308 EAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTP--RSKKKK 1365
SV K + + + D+ E L+ +P+ +T R+
Sbjct: 847 ----VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
Query: 1366 KLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKG 1406
+ G A P KT ++ K+D + +E G
Sbjct: 903 AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG 943
Score = 234 bits (597), Expect = 5e-61
Identities = 224/643 (34%), Positives = 278/643 (43%), Gaps = 162/643 (25%)
Query: 72 QAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
+A K S+ ESS+ EEE A A + + S V A P+ + A
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
GKTG PA K A S S E + ++ + G P AA+ P
Sbjct: 391 PGKTG-----PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKE 445
Query: 192 SAG------------------QADSSSEDTSSSSDETD-----------VEGKPSVKPAQ 222
S Q ED+ SSS+E+D + KP K Q
Sbjct: 446 SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 505
Query: 223 VKASSVSTKESPARKAAPAP-GKVGDVTPQVKGG-----------------------ALP 258
VK +S + A P P GKVG TP + G A+
Sbjct: 506 VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVA 565
Query: 259 PAK-------------------------------RAKKPEEESESSEEGSES--EEEAPA 285
PA+ +A+KP + SESSEE S+S EEAPA
Sbjct: 566 PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
Query: 286 G-TRSQVKASEKILQVRAA------SAPAKGTPGK---------GATPAPPGKAGAVASQ 329
T +Q K + KI Q +A +A AK P + G +P G + AVA
Sbjct: 626 AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGG 685
Query: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 389
T+ +P EDS SSSEES EE+T A + QAK+ GK QV AAS P K S +G AP
Sbjct: 686 TQ--RPAEDS-SSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV 742
Query: 390 PPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA--PAQAKPSGKAPQVRAASAPAKESP 447
PGKTGP V + +A K +EDS+SS EESDSEE A PAQ K S K Q +A A A+
Sbjct: 743 LPGKTGPTVTQVKAEK-QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 448 RKGAAPAP--------------PRKT---------------GPA-----------AAQVQ 467
KG AP P K GPA AAQ Q
Sbjct: 802 AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQ 861
Query: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG 527
G EEDS SS EESDS+ EA AQVKP GK+ Q++ A KGA P PPG
Sbjct: 862 TGP-EEDSGSSEEESDSEEEA---ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 917
Query: 528 KVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK 570
K GP+ +AQ GK ++DS SSSEES SDGE P AV AQ++
Sbjct: 918 KTGPS--AAQAGK-QDDSGSSSEES--DSDGEAPAAVTSAQDQ 955
Score = 117 bits (294), Expect = 6e-26
Identities = 124/372 (33%), Positives = 165/372 (44%), Gaps = 89/372 (23%)
Query: 73 AKKTRVSDPISTSESSEEEEE-AEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
A + + P+ SESSEE + A++E A A A ++ +P + K T
Sbjct: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL---KIPQTKACPKKTNTTA 652
Query: 132 AGKT-----GNSMPHPATGKTV----ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAF 182
+ K G P A T + ++G + R + + S++ SE E+ G
Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTV 712
Query: 183 G------------AAAKPGMVSAGQADS-----------------SSEDTSSSSDETDVE 213
G AA+ P S GQ + ED+ SS +E+D E
Sbjct: 713 GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSE 772
Query: 214 GKPSVKPAQVKASSVST--KESPARKAAP-------APGKVGDVTPQVK----------- 253
+ + PAQVK S T K +PA AP APGKV Q K
Sbjct: 773 -EAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV 831
Query: 254 -------------------GGALPPAKRAKK-PEEESESSEEGSESEEEAPAGTRSQVKA 293
G A+ A +A+ PEE+S SSEE S+SEEEA T +QVK
Sbjct: 832 RNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAE--TLAQVKP 889
Query: 294 SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET 353
S K Q+RAA APAK +P KGA P PPGK G A+Q AGK ++DS SSSEES DS+ E
Sbjct: 890 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ--AGK-QDDSGSSSEES-DSDGEA 945
Query: 354 PAAKALLQAKAS 365
PAA Q + S
Sbjct: 946 PAAVTSAQDQES 957
Score = 58.9 bits (141), Expect = 3e-08
Identities = 114/557 (20%), Positives = 197/557 (35%), Gaps = 102/557 (18%)
Query: 976 AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP-RIAPK 1034
A+ AA +K R S+ + S SSE E+E + TN + P + K
Sbjct: 65 AEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEK 124
Query: 1035 A------------SMAGASSSKESSRISDGKKQEGPA------TQVSK-KNPASLPLTQA 1075
A SM ++ K + + GK A T VS+ + S+P A
Sbjct: 125 AKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGA 184
Query: 1076 ALK---VLAQKASEAQPPVARTQPSSGVDSAVGTLPA----------TSPQSTSVQAKG- 1121
A K V A +A + + + + V+ PA SP + A G
Sbjct: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK 244
Query: 1122 ----TNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPS 1177
T +++ LP ++A K E S+ SE+ GSE + E P G +S
Sbjct: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEE------GSESEEEAPAGTRS------QVK 292
Query: 1178 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1237
+E +++ AA AP++ TP P + A+ P S ++
Sbjct: 293 ASEKILQVRAAS-------APAKGTPGKGATP--APPGKAGAVASQTKAGKPEEDSESSS 343
Query: 1238 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK-PKKGAGNPQASTLALQSNIT 1296
++ D ++E +A +L K GK + G +++ P+KGA
Sbjct: 344 EESSDSEEETPAAKA--LLQAKASGKTSQVGAASAPAKESPRKGAA-------------- 387
Query: 1297 QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAA 1356
P + +V K E++ + +++ES + + K SG P
Sbjct: 388 --------PAPPGKTGPAVAKAQAGKREEDSQ---SSSEESDSEEEAPAQAKPSGKAPQV 436
Query: 1357 RTPRSKKKKKLGAGEGGEASVSPEKTSTTSK----GKAKRDKASGDVKEKKGKGSLGSQ- 1411
R + K+ + G A P KT + GK + D S + + +L +
Sbjct: 437 RAASAPAKE---SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMN 493
Query: 1412 -------GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKA 1464
G + + GMG + G P K + E+ + + +
Sbjct: 494 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 553
Query: 1465 STKDSESPSQKKKKKKK 1481
+ D E P+ ++K
Sbjct: 554 DSSDGEVPTAVAPAQEK 570
Score = 41.6 bits (96), Expect = 0.006
Identities = 46/193 (23%), Positives = 81/193 (41%), Gaps = 24/193 (12%)
Query: 1308 EAQVQASVVKV-----LTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1362
+A +QA +V +E E+E + +T K + R + L D P++ ++K
Sbjct: 68 DAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLA-STNSSVLGADLPSSMKEKAK 126
Query: 1363 KKKKLGAGEGGEASVSPEKTSTTSK---GKAKRDKASGD-----VKEKKGKGSLGSQGAK 1414
+ + AG+ G + P T + GK+ R A V E + +GS+ + GA
Sbjct: 127 AETEK-AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 1415 DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1474
+P G V G Q++ S+ SD+ + + K + K +S ESP++
Sbjct: 186 AKP--------GMVSAG-QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 1475 KKKKKKKKTAEQT 1487
K K + T
Sbjct: 237 KAAPAPGKVGDVT 249
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 155 bits (393), Expect = 2e-37
Identities = 317/1398 (22%), Positives = 479/1398 (34%), Gaps = 241/1398 (17%)
Query: 100 KATPRLASTNSSV-LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPR 158
K +P ST+SS + +++ +K+ E GK +SM P + A+++ S
Sbjct: 568 KNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA 627
Query: 159 --KSAEPSANTTLVSETEEEGSVPAFGA-AAKPGMVSAGQADSSSEDTSSSSDETDVEGK 215
SA P ++L++ T V AF +A P V+ A +S T+++S +EG
Sbjct: 628 GPDSAGPLLKSSLITPT-----VAAFPLESADPAGVAPTTAKGTSTYTTTASPF--LEGT 680
Query: 216 PSVKPAQ--VKASSVST-------------KESPARKAAPAPGKV--GDVTPQVKGGALP 258
S+ P VK +++T SP AP V ++ V +LP
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLP 740
Query: 259 PAKR---AKKPEEESESSEEG--SESEEEAPA--GTRSQVKASEKILQVRAASAPAKGTP 311
PA KK + S +S + S +E P S +S+ L A S G
Sbjct: 741 PAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVS 800
Query: 312 GKGATPAPPGKAGAVASQTKAGK------PEE-----DSESSSEESSDSEEET-----PA 355
T PP K G+ T G P E ++ S + S DS T P+
Sbjct: 801 VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
K A S G + P KE+P P K GPA
Sbjct: 861 PKGAPTPSAVTPLSPKGV-TLPPKETPTPSVVNLPFPKEGPA------------------ 901
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPA--KESPRKGAAPAPPRKTGPAAAQVQVGKQEE 473
+ + ++APA + S + RA AP SP AP PP T P
Sbjct: 902 -TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP------------ 948
Query: 474 DSRSSSEESDSDREALAAMNAAQVKPLG----KSPQVKPASTMGMGPLGKGAGPVPPGKV 529
S + S + A A P G SP+ P P KG GP P
Sbjct: 949 -SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG-GPATPSPK 1006
Query: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
G TP A + S +++ +S T +P + + + PT+ A P
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Query: 590 QKAGPVAVQVK-AEKPMDNSESSEESSDSADSEEA---PAAMTAAQAKPALKIPQTKACP 645
K GP +K A P + S + + S + P A T K L P K P
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
Query: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEK 705
TT +A + G P G T+PA + P+ GG P + + + +
Sbjct: 1127 ----TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 706 TGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT-----APVLPGKTGPTVTQVKAEKQE 760
G G A KG A+ P G T AP P T P + K
Sbjct: 1183 KG-----GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP------SPKGG 1231
Query: 761 DSESSEEESDSEEAAASPA-QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 819
+ S + + + AA P+ + + + P AA PS KG ++ P
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP-------PHK 1284
Query: 820 KQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEE 879
+P+ V PP +P+ GPA+ P G AA P GS
Sbjct: 1285 GAPNPAVVTPP--SPKG------GPATSPPKGAPTPPAAT----PPSPKGS--------- 1323
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
P K +P A TPP G A G + S
Sbjct: 1324 ------------------PGTPPPKGAPTPPAV-TPPSPKGTPTLPATTPSSKGGPTTPS 1364
Query: 940 DSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA---TPAQAQAASTPRKARASESTARS 996
+G P A T + P + P R PA P+ + A +P+KA A+ T
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
+++ S+ + PA +TP V++ A APK
Sbjct: 1425 AATPSKGDLTPPA---VTP------VSLKKAPATSAPKG--------------------- 1454
Query: 1057 GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTS 1116
GPAT SK +P +T + K A + P++ TLPA P S
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514
Query: 1117 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTP 1176
+ R P P +K ++ +++ A T+ P+P
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL---------------IPPAMTV-PSP 1558
Query: 1177 SRTETL--VEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSST 1234
+T + +E A S + +P P +TP+ + + + +L P+V+S
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSP----------PAVTPSTYKGAPSPKELLIPPAVTSP 1608
Query: 1235 LAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSN 1294
+ K+ P P G +P G + TP K +P + T + +
Sbjct: 1609 -SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSL---KDSPTSPASVTCKMGAT 1664
Query: 1295 ITQCLLGQP---WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSR--------KGWE 1343
+ Q G P P +V + T ++ +K T K S+
Sbjct: 1665 VPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKN 1724
Query: 1344 SRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKK 1403
K LS PA P K K +G +AS SP+ + KA + ++
Sbjct: 1725 GSKGPLSTVAPAPLLPVQKDSSK--TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782
Query: 1404 GKGSLGSQGAKDEPEEEL 1421
K S A P L
Sbjct: 1783 PKPESASVSAAPSPPVSL 1800
Score = 89.7 bits (221), Expect = 2e-17
Identities = 163/707 (23%), Positives = 261/707 (36%), Gaps = 96/707 (13%)
Query: 216 PSVKPAQVKASSVSTKESPA----RKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESE 271
P P +S K++PA R+ A P K GD+TP A+ P K P +
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAATPSK-GDLTPP----AVTPVSLKKAPATSAP 1452
Query: 272 S---SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328
+ S+ + PA T K QV +S+P K ATPAP G A
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP----ATPAPMG-----AP 1503
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 388
A P E + SS + P A L S KT PA +P++ A
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLL-----SKKT--------PATLAPKE--AL 1548
Query: 389 APPGKTGPAVAKAQA--GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
PP T P+ K A +E + SS+E+ S +P+ PA S
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK-ELLIPPAVTS 1607
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
P AP PP T P+ + + + +S + S L SP
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS--------------LKDSPTS 1653
Query: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
+ T MG A P K GP +E + + ES+ PT P
Sbjct: 1654 PASVTCKMGATVPQASKGLPAKKGPTA-------LKEVLVAPAPESTPIITA--PTRKGP 1704
Query: 567 AQEKSLGNILQAKPTSSP---AKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEA 623
+KS P S +KGP P + + +K + +++S S A
Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPKGPLA 1763
Query: 624 P------AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA- 676
P +TAA + L P++ + + S +AP V T P++ +SP
Sbjct: 1764 PPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL 1823
Query: 677 ---GSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPV-K 732
S +A + E + V + KS G + +A PV K
Sbjct: 1824 VLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTK 1883
Query: 733 GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKA 792
+ G GT ++ + + E+Q+ ++++ ++ ++ AAA+ + K Q+++
Sbjct: 1884 NNKGSGT------ESDSDESVPELEEQDSTQATTQQ--AQLAAAAEIDEEPVSKAKQSRS 1935
Query: 793 NPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV-RNPQNSTVLARGPASVPSVG 851
A +A S G G ++K KP V ++P + T + G A + +
Sbjct: 1936 EKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLS 1995
Query: 852 KAVATAAQAQTGPEEDSGSS----------EEESDSEEEAETLAQVK 888
+ AA + + ++ S+ +EES+ EE ET +VK
Sbjct: 1996 QQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVK 2042
Score = 46.2 bits (108), Expect = 2e-04
Identities = 200/920 (21%), Positives = 299/920 (32%), Gaps = 147/920 (15%)
Query: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 512
P +T PA Q Q E + + S AL P +PQ P S
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 513 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
A P P +TP E +SS + +P AP L
Sbjct: 62 NQ------ASPFPSPSTIASTPL----------EVPFPQSSSGT--ALPLGTAPEAPTFL 103
Query: 573 GNILQ----------AKPTSSPA-KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE 621
N++ A P +P KG P + P+A+ A + S S+ +
Sbjct: 104 PNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS-----SAFPPNLL 158
Query: 622 EAPAAMTAAQAKPALKI--PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSS 679
+P ++ A++ + + P + PK ++V P GT +P P S
Sbjct: 159 TSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP--------PCIVS 210
Query: 680 PAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV----KAASVPVKGSL 735
A S T LA+ Q K + S+ +KG +
Sbjct: 211 TVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPV 270
Query: 736 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ--AKAN 793
A L ++ P VT ++K + + S + +P ++S Q +
Sbjct: 271 SPPAALSLSTQSLPVVTS--SQKTAGPNTPPDFPISLGSHLAPLH-QSSFGSVQLLGQTG 327
Query: 794 PAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV--RNPQNSTVLARGPASVPSVG 851
P+A P+ K TIS T A+ QRS V PP+ RN +A P PSV
Sbjct: 328 PSALSDPTVK-TISVDHSS-TGASYPSQRS---VIPPLPSRNEVVPATVAAFPVVAPSVD 382
Query: 852 KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911
K +T + P SGS + T +K S +A + P
Sbjct: 383 KGPSTISSITCSP---SGSLNVATSFSLSPTTSLILKSSPNATYHYPLVA---QMPVSSV 436
Query: 912 APTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP--NRSPA 969
TP T P A AP P + P N P
Sbjct: 437 GTTPLVVTNPCTIAA------------------APTTTFEVATCVSPPMSSGPISNIEPT 478
Query: 970 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDV--IPATQCLTPGIRTNVVTMPTA 1027
PAA A P A+ S + ED+ +P++ + + ++ T+P
Sbjct: 479 SPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVP-- 536
Query: 1028 HPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEA 1087
AS+ GA S + ++ +KK+P LPL QAA K S +
Sbjct: 537 -------ASLEGAPFSPAQAGLT------------TKKDPTVLPLVQAAPKNSPSFQSTS 577
Query: 1088 QPPVARTQPSSGV--DSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD 1145
P P + + S LP P S+ G N S
Sbjct: 578 SSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVN-------------------SSA 618
Query: 1146 SEDSSDSSSGSEEDGEGPQGAKSAHTLG--PTPSRTETLVEETAAESSEDDVVAPSQSLL 1203
S +DS +G + G + + T+ P S V T A+ + S L
Sbjct: 619 SVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLE 678
Query: 1204 SGYMTPGLTPANSQASKAT-PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGG 1262
T L P N + T L P+ S P Q A +L+P+
Sbjct: 679 G---TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSP---QNTCAPLATLVLAPEI-P 731
Query: 1263 KEAASGTTPQKSRKP--KKGAGNPQASTLA-LQSNITQCLLGQPWPLNEAQVQASVVKVL 1319
K S + P P KK G S LA + S+ +C P + A AS L
Sbjct: 732 KSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKEC----PTEDSGASATASSKGTL 787
Query: 1320 TELLEQERKKVVDTTKESSR 1339
T L + V + ++ R
Sbjct: 788 TYLADSPSPLGVSVSPQTKR 807
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 149 bits (375), Expect = 3e-35
Identities = 209/798 (26%), Positives = 297/798 (37%), Gaps = 169/798 (21%)
Query: 1 MAEARKRR----ELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQT 56
MA+A RR +L PL+ L A + + +G A +LLDIY+ W ++
Sbjct: 1 MADAGIRRVVPSDLYPLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLKS 60
Query: 57 SEL-GRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGA 115
+++ RK +A A +AKK S + +SSEEEEE + AK
Sbjct: 61 AKVPERKLQANGPVAKKAKKKASSS--DSEDSSEEEEEVQGPPAK--------------- 103
Query: 116 DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
KA ++ G +P GK A S +S++ + +
Sbjct: 104 --------KAAVPAKRVG-----LP---PGKAAAKASESSSSEESSDDDDEEDQKKQPVQ 147
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPA 235
+G P AA P A +DS S+ SSS DE KP + P VKA +
Sbjct: 148 KGVKPQAKAAKAPPK-KAKSSDSDSD--SSSEDEPPKNQKPKITPVTVKAQT-------- 196
Query: 236 RKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASE 295
KA P P + P++ G +A S SS +SEEE
Sbjct: 197 -KAPPKPAR---AAPKIANG------KAASSSSSSSSSSSSDDSEEE------------- 233
Query: 296 KILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
+AA+ P K P K P KA A P S SS + SSD EEE
Sbjct: 234 -----KAAATPKKTVPKKQVVAKAPVKA--------ATTPTRKSSSSEDSSSDEEEE--- 277
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
K ++ K G S V SAP P+K PP K AV K Q + EDS S+
Sbjct: 278 QKKPMKNK-PGPYSSVPPPSAP---PPKKSLGTQPPKK---AVEKQQPVESSEDSSDESD 330
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
S EE+ P P K K PP K+ +S
Sbjct: 331 SSSEEEKKP-----------------PTKAVVSKATTKPPP------------AKKAAES 361
Query: 476 RSSSEESDSDREALAAMNAAQVKPLG--KSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
S S +SDS + + A KP G K+ KPA T + A P P G
Sbjct: 362 SSDSSDSDSSED-----DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL 416
Query: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG 593
+ + DS SS EESS S + + VA + K+ S PAK PQ +
Sbjct: 417 LTRKA-----DSSSSEEESSSSEEEKTKKMVATTKPKATAK----AALSLPAKQAPQGS- 466
Query: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTN 649
SS+ S S++ EE + +A + KP P A KK
Sbjct: 467 -------------RDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGK 513
Query: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES-DSEEEKTGL 708
+S + + K SP +P G + A++ +++ S + EEEK
Sbjct: 514 AESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKA 573
Query: 709 AVTVGQAKSVGKGLQ---VKAASVPVKGSLGQGTAPVLPGK-------TGPTVTQVKAEK 758
AV V ++ S+ K Q K A P + T P + + P + E
Sbjct: 574 AVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEI 633
Query: 759 QEDSESSEEESDSEEAAA 776
+ DS ++ D++ AA
Sbjct: 634 EVDSRVADNSFDAKRGAA 651
Score = 143 bits (360), Expect = 1e-33
Identities = 200/753 (26%), Positives = 277/753 (36%), Gaps = 196/753 (26%)
Query: 258 PPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
P AK+AKK S+S E+ SE EEE + A+ PAK
Sbjct: 73 PVAKKAKKKASSSDS-EDSSEEEEEVQGPP------------AKKAAVPAK------RVG 113
Query: 318 APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 377
PPGKA A AS++ SSSEESSD ++E K +Q
Sbjct: 114 LPPGKAAAKASES----------SSSEESSDDDDEEDQKKQPVQKGVK------------ 151
Query: 378 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 437
P+ AA APP K S S +S SE+E P KP V+
Sbjct: 152 ----PQAKAAKAPPKKA--------------KSSDSDSDSSSEDEPPKNQKPKITPVTVK 193
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
A + ++P K A AP G AA+ S SSS++S+ ++ A
Sbjct: 194 AQT----KAPPKPARAAPKIANGKAASS----SSSSSSSSSSDDSEEEKAAATPKKTVPK 245
Query: 498 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 557
K + VK A+T P K + S+ EE+ + ++
Sbjct: 246 KQVVAKAPVKAATT-------------PTRKSSSSEDSSSD---EEEEQKKPMKNKPGPY 289
Query: 558 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS 617
VP AP +KSLG PP+KA V+ ++P+++SE S + SDS
Sbjct: 290 SSVPPPSAPPPKKSLGT------------QPPKKA------VEKQQPVESSEDSSDESDS 331
Query: 618 ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 677
+ EE K P TKA K T K P +
Sbjct: 332 SSEEE--------------KKPPTKAVVSKATT----KPPPAK----------------- 356
Query: 678 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 737
+ AE SS S +SDS E+ + G K+ V S VK +
Sbjct: 357 ----------KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPA--- 403
Query: 738 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKA--NPA 795
AP P G + KA DS SSEEES S E + V T+ K AKA +
Sbjct: 404 -AAPKQPVGGGQKLLTRKA----DSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLP 458
Query: 796 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA 855
A +AP S+ ++ + ++ S S VK + PQ + G A +
Sbjct: 459 AKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVK---KKPQK-----------VAGGAAPS 504
Query: 856 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
A A+ G E S SS + SEEE E L K SPR P
Sbjct: 505 KPASAKKGKAESSNSSSSDDSSEEEEEKL-----------------KGKGSPR----PQA 543
Query: 916 PGKTGPSA--AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 973
P G SA AQ GK + +SEE + + + A V S + + P A
Sbjct: 544 PKANGTSALTAQNGK---AAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQA 600
Query: 974 TPAQAQAASTPRKARASESTARSSSSESEDEDV 1006
+ Q +T K + E A S +E++
Sbjct: 601 KKIKLQTPNTFPKRKKGEKRASSPFRRVREEEI 633
Score = 138 bits (348), Expect = 3e-32
Identities = 169/658 (25%), Positives = 246/658 (37%), Gaps = 137/658 (20%)
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV----- 223
L S E + A G AK A SSS+ SS +E +V+G P+ K A
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKA----SSSDSEDSSEEEEEVQGPPAKKAAVPAKRVG 113
Query: 224 ----KASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSES 279
KA++ +++ S + +++ + V+ G P AK AK P ++++SS+ S+S
Sbjct: 114 LPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDS 173
Query: 280 --EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE 337
E+E P + ++ Q +A PA+ P GKA + +S
Sbjct: 174 SSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAP-----KIANGKAASSSS--------- 219
Query: 338 DSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPA 397
S SSS S DSEEE AA+ P K P+K P K
Sbjct: 220 -SSSSSSSSDDSEEEK-------------------AAATPKKTVPKKQVVAKAPVKAATT 259
Query: 398 VAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPR 457
+ SSSE+S S+EE + K + P+ P+K PP+
Sbjct: 260 PTR---------KSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK 310
Query: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517
K V+ + E S SS+ESDS E K P K
Sbjct: 311 KA------VEKQQPVESSEDSSDESDSSSEE------------EKKPPTKAV-------- 344
Query: 518 GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGN--I 575
V AT K +S S S +S S D E P+ A + S +
Sbjct: 345 -----------VSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAV 393
Query: 576 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--------EAPAAM 627
P PA P Q G Q + D+S S EESS S + + + A
Sbjct: 394 TTKSPAVKPAAAPKQPVG--GGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATA 451
Query: 628 TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK--AGTATSPAGSSPAVAGG 685
AA + PA + PQ + ++S++ + A +K A A S PA A
Sbjct: 452 KAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKK 511
Query: 686 TQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG 745
+ + +SSSS++S EEE+ K GKG + AP G
Sbjct: 512 GKAESSNSSSSDDSSEEEEE----------KLKGKGSP-------------RPQAPKANG 548
Query: 746 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK 803
+ T KA K +SEEE + ++ AA S+KK + A P AK
Sbjct: 549 TSALTAQNGKAAK-----NSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAK 601
Score = 122 bits (307), Expect = 2e-27
Identities = 165/630 (26%), Positives = 245/630 (38%), Gaps = 123/630 (19%)
Query: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA 924
++ + SS+ E SEEE E Q P+ K A PAK PPGK
Sbjct: 79 KKKASSSDSEDSSEEEEEV--QGPPAKK------AAVPAKR------VGLPPGKA----- 119
Query: 925 QAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 984
A K +S SS E SD D E D + P P A + P
Sbjct: 120 -AAKASESSSSEESSDDDDEE-----------------DQKKQPVQKGVKPQAKAAKAPP 161
Query: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPT-AHPRIAPKASMAGASSS 1043
+KA++S+S + SSS + ++ P +T +T P A P+IA + + +SSS
Sbjct: 162 KKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSS 221
Query: 1044 KESSRISDGKKQEGPATQ---VSKKNP-ASLPLTQAALKVLAQKASEAQPPVARTQPSSG 1099
SS D ++++ AT V KK A P+ A +SE +
Sbjct: 222 SSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKP 281
Query: 1100 VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEED 1159
+ + G + P S K K E QQ ESS+DS D SDSSS EE+
Sbjct: 282 MKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPV---ESSEDSSDESDSSS--EEE 336
Query: 1160 GEGPQGAK-SAHTLGPTPSR--TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1216
+ P A S T P P++ E+ + + ++SSEDD APS+ G T +S
Sbjct: 337 KKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE-APSKPA-------GTTKNSS 388
Query: 1217 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1276
T K SP+V A K G Q+ ++A + E S ++ ++ K
Sbjct: 389 NKPAVTTK---SPAVKPAAAPKQPVGGGQKLLTRKA------DSSSSEEESSSSEEEKTK 439
Query: 1277 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1336
P+A+ A L K+ +++
Sbjct: 440 KMVATTKPKATAKAA-------------------------------LSLPAKQAPQGSRD 468
Query: 1337 SSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKAS 1396
SS S S ++ +T +S KKK GG A P K ++ KGKA+ +S
Sbjct: 469 SSSDSDSS-----SSEEEEEKTSKSAVKKKPQKVAGGAA---PSKPASAKKGKAESSNSS 520
Query: 1397 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEG-GDQSNPKSKKEKKKSDKRKKDKEKK 1455
S E EEE KG G+ ++N S + K +E++
Sbjct: 521 -------------SSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEE 567
Query: 1456 EKKKKAKKASTKDSESPSQKKKKKKKKTAE 1485
E+K KKA+ S+S S KK+K+ + E
Sbjct: 568 EEK---KKAAVVVSKSGSLKKRKQNEAAKE 594
Score = 116 bits (291), Expect = 1e-25
Identities = 150/611 (24%), Positives = 233/611 (38%), Gaps = 96/611 (15%)
Query: 900 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959
L AK RK A P K A + +DS EE AAV + +V PP
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG 117
Query: 960 IFV-------------------DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
D + P P A + P+KA++S+S + SSS +
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED 177
Query: 1001 SEDEDVIPATQCLTPGIRTNVVTMPT-AHPRIAPKASMAGASSSKESSRISDGKKQEGPA 1059
++ P +T +T P A P+IA + + +SSS SS D ++++ A
Sbjct: 178 EPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAA 237
Query: 1060 T---QVSKKN-PASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQST 1115
T V KK A P+ A +SE + + + G + P S
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSA 297
Query: 1116 SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPT 1175
K K E QQ ESS+DS D SDSSS EE + S T P
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPV---ESSEDSSDESDSSS-EEEKKPPTKAVVSKATTKPP 353
Query: 1176 PSR--TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSS 1233
P++ E+ + + ++SSEDD APS+ G T +S T K SP+V
Sbjct: 354 PAKKAAESSSDSSDSDSSEDD-EAPSK-------PAGTTKNSSNKPAVTTK---SPAVKP 402
Query: 1234 TLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1293
A K G Q+ ++A + E S ++ ++ K P+A+ A
Sbjct: 403 AAAPKQPVGGGQKLLTRKA------DSSSSEEESSSSEEEKTKKMVATTKPKATAKA--- 453
Query: 1294 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1353
L+ +Q + D++ +S E + K S
Sbjct: 454 ------------------------ALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTS--- 486
Query: 1354 PAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEK-KGKGSLGSQG 1412
++ KK +K+ G S +K S + D +S + +EK KGKGS
Sbjct: 487 ---KSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGS----- 538
Query: 1413 AKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKK-----DKEKKEKKKKAKKASTK 1467
P + K GT Q+ +K +++ +++KK K KK+K +A+ K
Sbjct: 539 ----PRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA-K 593
Query: 1468 DSESPSQKKKK 1478
++E+P KK K
Sbjct: 594 EAETPQAKKIK 604
Score = 105 bits (261), Expect = 4e-22
Identities = 174/711 (24%), Positives = 271/711 (38%), Gaps = 142/711 (19%)
Query: 796 AARAPSAKGTISAP--GKVVTAAAQAKQRSPSKVKPPVRNP--QNSTVLARGPASVPSVG 851
+A+ P K + P K A+ + S+ + V+ P + + V A+ P G
Sbjct: 60 SAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPP--G 117
Query: 852 KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911
KA A A++ S SSEE SD ++E + Q G Q +AA AP K++
Sbjct: 118 KAAAKASE--------SSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK---- 165
Query: 912 APTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA---AVTSAQVIKPPLIFVDPNRSP 968
DS SSSE+ + P AQ PP P
Sbjct: 166 ---------------SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPP--------KP 202
Query: 969 AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP--T 1026
A A A +AAS+ S S++ SSSS+ +E+ AT T + V P
Sbjct: 203 ARAAPKIANGKAASS------SSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKA 256
Query: 1027 AHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL-AQKAS 1085
A +S +SS +E + K + GP + V P S P + +L +KA
Sbjct: 257 ATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVP---PPSAPPPKKSLGTQPPKKAV 313
Query: 1086 EAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD 1145
E Q PV ++ SS +S + P + +V +K T K A KA ESS D
Sbjct: 314 EKQQPVESSEDSSD-ESDSSSEEEKKPPTKAVVSKATTK--------PPPAKKAAESSSD 364
Query: 1146 SEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG 1205
S DS SS +E P G + P + V+ AA V Q LL+
Sbjct: 365 SSDS--DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQP---VGGGQKLLTR 419
Query: 1206 YMTPGLTPANSQASK--------ATPKLDSSPSVSSTLAAKDDPDGKQEA---------- 1247
+ S +S+ AT K ++ + +L AK P G +++
Sbjct: 420 KADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSE 479
Query: 1248 -------------KPQQAAGMLSP------KTGGKEAASGTTPQKSRKPK----KGAGNP 1284
KPQ+ AG +P K G E+++ ++ S + + KG G+P
Sbjct: 480 EEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSP 539
Query: 1285 QASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWES 1344
+ A ++N T L Q K E E+++K V +K S K
Sbjct: 540 RPQ--APKANGTSALTAQ---------NGKAAKNSEEEEEEKKKAAVVVSKSGSLK---- 584
Query: 1345 RKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG 1404
KRK + A TP++KK + + +T K K +AS + +
Sbjct: 585 -KRKQNEAAKEAETPQAKK-------------IKLQTPNTFPKRKKGEKRASSPFRRVRE 630
Query: 1405 KGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKK 1455
+ D + + G + G+++N K K KS + +K K+K+
Sbjct: 631 EEIEVDSRVADNSFDAKRGAAG--DWGERANQVLKFTKGKSFRHEKTKKKR 679
Score = 63.9 bits (154), Expect = 1e-09
Identities = 73/300 (24%), Positives = 121/300 (40%), Gaps = 50/300 (16%)
Query: 73 AKKTRVSDPISTSESSEEEEEAEAETAKAT------PRLASTNSSVLGADLP-------- 118
AKK S S+ S E++EA ++ A T P + + + +V A P
Sbjct: 355 AKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 119 ----------SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
SS +E + +E EK K + AT K +L + ++P+ S + S+++
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 169 LVSETEEE-----------------GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
S EEE G+ P+ A+AK G A ++SSS D SS +E
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKG--KAESSNSSSSDDSSEEEEEK 532
Query: 212 VEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV-----KGGALPPAKR--AK 264
++GK S +P KA+ S + KAA + + + K G+L K+ A
Sbjct: 533 LKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA 592
Query: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324
K E ++ + ++ P + + +AS +VR + A G AG
Sbjct: 593 KEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAG 652
Score = 53.9 bits (128), Expect = 1e-06
Identities = 81/377 (21%), Positives = 143/377 (37%), Gaps = 82/377 (21%)
Query: 1125 LRKPKLPE--------VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA---HTLG 1173
L+ K+PE V + K SS DSEDSS+ EE+ +GP K+A +G
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEE----EEEVQGPPAKKAAVPAKRVG 113
Query: 1174 PTPSRTETLVEETAA--ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSV 1231
P + E+++ ESS+DD + + G+ P ++A+KA PK S
Sbjct: 114 LPPGKAAAKASESSSSEESSDDD---DEEDQKKQPVQKGVKP-QAKAAKAPPKKAKSSDS 169
Query: 1232 SSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLAL 1291
S +++D+P Q+ K ++P T +A + P+ +R K A AS+
Sbjct: 170 DSDSSSEDEPPKNQKPK-------ITPVT--VKAQTKAPPKPARAAPKIANGKAASS--- 217
Query: 1292 QSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG 1351
++ SS +S + K
Sbjct: 218 ----------------------------------------SSSSSSSSSSDDSEEEK--- 234
Query: 1352 DQPAARTPRSK-KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1410
AA TP+ KK++ A +A+ +P + S++S+ + ++ K G S
Sbjct: 235 ---AAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS 291
Query: 1411 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSE 1470
P + K +GT + E + + D +E+KK KA +
Sbjct: 292 VPPPSAPPPK--KSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 1471 SPSQKKKKKKKKTAEQT 1487
+ KK + +++ +
Sbjct: 350 TKPPPAKKAAESSSDSS 366
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 124 bits (312), Expect = 5e-28
Identities = 317/1561 (20%), Positives = 537/1561 (34%), Gaps = 243/1561 (15%)
Query: 85 SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP-- 142
S+ SEEE A L + A+ PS M K + ++ K P P
Sbjct: 46 SQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS-MHRKQELDSSHPPKQSGRPPDPGR 104
Query: 143 ------ATGKTVANL-----LSGKSPRK-SAEPSANTTLVSETEEEGSVPAF-----GAA 185
+ +T L G+SP S + S + T + E + +P F +
Sbjct: 105 PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALS 164
Query: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
A +V+ D+ +S +ET + K V+ Q K + + P P +
Sbjct: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQ 223
Query: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305
G ++ P + +++PE+ +S G+ + P T A K+ R AS
Sbjct: 224 GPGRDPLQQDGTPKSISSQQPEK-IKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRDASR 280
Query: 306 P----AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 361
P A G+ P+ P + Q GKP + E+S + PA
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPA------ 333
Query: 362 AKASGKTSQVGAASAPAKESPRKGAAPA-PPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Q + P + P P PPG T P A+ + Q+ SE+ SE
Sbjct: 334 --------QPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSSE 384
Query: 421 EEAP-AQAKPSGKAPQVRAASAPAKESPRKGAAP----------APPRKTGPAAAQVQ-- 467
+ P A A+P G PAK ++ P +P + GP VQ
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 468 -----VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG---PLGK 519
+Q ++S++++ + A+ P P P G
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
Query: 520 GAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ-- 577
G+ PP + GPA PS Q + S + S + P+ P+ ++S + Q
Sbjct: 505 GSTKPPPQQPGPAKPSPQ--QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 578 -AKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES-----SEESSDSADSEEAPAAMTAAQ 631
KP P P K P K P+ N+ E+++ + +E +
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622
Query: 632 AKPALKIPQTKA-----CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 686
P + + K C K +APV Q K T+P ++ AV+ +
Sbjct: 623 FNPNPHLTEVKEWLCLNCQMK--RALGGDLAPVPSSPQPKLK----TAPVTTTSAVSKSS 676
Query: 687 QRPAEDSSSSEESDSEE---------------------EKTGLAVTVGQAKSVGKGLQVK 725
+P + S + + ++ + A +A S+ K K
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736
Query: 726 AASVPVKGSLGQGTAPVLPGK---------TGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
SVP + Q APV K T V+ A + D SS+ +S +EE
Sbjct: 737 EPSVPSE----QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 777 SP-----AQVKTSVKKTQAKANP----AAARAPSAKGTISAPGKVVTAAAQ------AKQ 821
P A+ S T K +P A R S IS PG + Q K+
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKK 852
Query: 822 RSPSKVKPPVRNPQNSTVLARG----PASVPSVGKAVATAAQAQTGPEED---SGSSEEE 874
P K + + ++ + +G P P+ G+ V T Q+ E+ S +
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSI 912
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAAL-----------------------APAKESPRKGA 911
+D+ + T Q +GK A++ AP K++P
Sbjct: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972
Query: 912 APT---PPGKTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
PT PP TG P+ + K++ ++E+ + E V + K P
Sbjct: 973 PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----P 1028
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 1023
P + A P +A + K+ EST +E P + V
Sbjct: 1029 PIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
Query: 1024 M----PTAH-PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALK 1078
+ PT H I + + S ++ D +K PA K +P +P ++ K
Sbjct: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-PAPSGPKASPMPVPTESSSQK 1147
Query: 1079 VLAQ---KASEAQPPVARTQPSSGVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPE 1132
K + Q +T+ + V ++ P T+ Q + +KL K K
Sbjct: 1148 TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASA 1207
Query: 1133 VQQATKAPES-----SDDSEDSSDSSSGSEEDGEGPQGAK---SAHTLGPTPSRTETLVE 1184
+Q+ PE ++ S + EE P+ K A T P + + L
Sbjct: 1208 LQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKS 1267
Query: 1185 ET-AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1243
+ AE + VAP + S ++ PK D +T K+ P
Sbjct: 1268 QVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD----KTTKTIKEQPQP 1323
Query: 1244 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1303
AKP Q KT ++ S T+ + K +G + S+ + S++ + +
Sbjct: 1324 PCTAKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPSL 1380
Query: 1304 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAAR 1357
P +E + + K D+ + S S KL + A+
Sbjct: 1381 IPTDEKDILKGLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426
Query: 1358 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1417
K +KK E VSPE+ K ++ + + E++ K S ++E
Sbjct: 1427 LADEKSEKKTQPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEER 1475
Query: 1418 EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1477
++ +K Q P SK K+KS+ ++E +++S ++ Q+K+
Sbjct: 1476 KDTFKK------DSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKR 1529
Query: 1478 K 1478
+
Sbjct: 1530 R 1530
Score = 119 bits (297), Expect = 3e-26
Identities = 316/1501 (21%), Positives = 506/1501 (33%), Gaps = 277/1501 (18%)
Query: 80 DPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSM 139
D IS SE+S+EE T K + G P ++ K ++ G + +
Sbjct: 177 DLISDSEASQEE------TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
Query: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
T K++++ K KS P + T+ P A P Q D+S
Sbjct: 231 QQDGTPKSISSQQPEKI--KSQPPGTGKPIQGPTQ----TPQTDHAKLPL-----QRDAS 279
Query: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP 259
T + D+ SVKP S S + P ++ P PGK PP
Sbjct: 280 RPQTK----QADIVRGESVKP-----SLPSPSKPPIQQ--PTPGK-------------PP 315
Query: 260 AKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA-PAKGTPGKGATPA 318
A+ + G E + PA +Q K L + + P PG PA
Sbjct: 316 AQ------------QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 319 PP-GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT--------- 368
P G A A QT + KP E P KAL Q GKT
Sbjct: 364 QPLGPAKPPAQQTGSEKPSS--------------EQPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 369 ---SQVGA----ASAPAKESPRKGAAPA--PPGKTGPAVAKAQ-AGKREEDSQSS----- 413
QVG A P +SP K P P + GP AQ AG + +Q +
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 414 -SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
S+ + P Q P+ PQ ++ P + P G+ PP++ GPA Q
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKPSPQ----- 522
Query: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532
+ S + S + A +A Q P S Q ST + G G P+ P V P+
Sbjct: 523 ---QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ---QSTKPVSQTGSGK-PLQPPTVSPS 575
Query: 533 T---PSAQVGKW-------EEDSESSSEESSDSSDGEVPTAVAPA--------------- 567
PS + K E E+++ ++ E T V
Sbjct: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635
Query: 568 ------QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE 621
+++LG L P+S P K PV K + + D+A +
Sbjct: 636 LCLNCQMKRALGGDLAPVPSSPQ---PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ 692
Query: 622 EAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR--VGTQAPRKAGTATSPAGSS 679
+ A + P +K P P +A AK P + AP K + S +
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSP-----SAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Query: 680 PAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 739
P ++P +++ S T + + +S + + + P+K + +
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE----EKTTPPLKTDSAKPS 803
Query: 740 APVLPG--KTGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKAN 793
P K P ++ DS+ S E+ P Q K KK Q K +
Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS 863
Query: 794 PAAARAPSAKGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVG 851
P P KG+ + PG TA Q+SP + R N + P S P+
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT-- 921
Query: 852 KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911
T + TG G+S S + T Q P H AP K++P
Sbjct: 922 ----TPQETVTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQ 972
Query: 912 APT---PPGKTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
PT PP TG P+ + K++ ++E+ + E V + K P
Sbjct: 973 PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----P 1028
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 1023
P + A P +A + K+ EST +E P + V
Sbjct: 1029 PIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
Query: 1024 M----PTAH-PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALK 1078
+ PT H I + + S ++ D +K PA K +P +P ++ K
Sbjct: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-PAPSGPKASPMPVPTESSSQK 1147
Query: 1079 VLAQ---KASEAQPPVARTQPSSGVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPE 1132
K + Q +T+ + V ++ P T+ Q + +KL K K
Sbjct: 1148 TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASA 1207
Query: 1133 VQQATKAPESS-----DDSEDSSDSSSGSEEDGEGPQGAK---SAHTLGPTPSRTETLVE 1184
+Q+ PE ++ S + EE P+ K A T P + + L
Sbjct: 1208 LQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKS 1267
Query: 1185 ETA-AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1243
+ AE + VAP + S ++ PK D +T K+ P
Sbjct: 1268 QVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK----TTKTIKEQPQP 1323
Query: 1244 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1303
AKP Q KT ++ S T+ + K +G + S+ + S++ +
Sbjct: 1324 PCTAKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE------ 1376
Query: 1304 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1363
+ L+ + K ++ K+ +S ++ S P+
Sbjct: 1377 ---------------IPSLIPTDEKDILKGLKK------DSFSQESSPSSPS-------- 1407
Query: 1364 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1423
L E S+ + ST + K+++ +V ++ K +Q + E +
Sbjct: 1408 --DLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITIS- 1464
Query: 1424 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES--PSQKKKKKKK 1481
++E KE +++ K KDS+ PS K K+K
Sbjct: 1465 ---------------------------EEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS 1497
Query: 1482 K 1482
+
Sbjct: 1498 E 1498
Score = 95.9 bits (237), Expect = 3e-19
Identities = 249/1181 (21%), Positives = 408/1181 (34%), Gaps = 188/1181 (15%)
Query: 113 LGADL---PSSMKEKAK-AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
LG DL PSS + K K A S P P + + K+ EP
Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQ-ADSSSEDTSSSSDETDV-EGKPS----VKPAQ 222
LV + GS P+ A P S + A S D+ V + KP VKP
Sbjct: 706 LVKQPTLHGS-PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 223 --VKASSVSTK--------ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
V +SS +TK +S A + P K P + PP P +
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ---SFPPTGEKVSPFDSKAI 821
Query: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGT----------PGKGATPAPPGK 322
S+S+ + G S+ K +++ V+ P K P +P PPG
Sbjct: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881
Query: 323 ---AG-AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS-AP 377
AG V + ++ KP+E S S + + Q +GK GA+ +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 378 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 437
A P P ++GP QA + S K +G+AP
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP-----------KSTGQAPPAP 990
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
A S P K+ + AA K P A Q K+ E + DS A
Sbjct: 991 AKSIPVKKETKAPAA----EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP 1046
Query: 498 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-------------PSAQVGKWEE- 543
L KSP KP ST + G P T P+ + + +E
Sbjct: 1047 TKLEKSP--KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 544 -DSESSSEESSDSSDGEV-PTAVAPAQEKSLGNILQAKPTSSPAKGPPQ----KAGPVAV 597
++ + G++ AP+ K+ + + +S PPQ K V
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP--KKTNTTASAK 655
+ +AEK + E+ ++ E+ P +T Q + K+ + KA +K K
Sbjct: 1165 KTEAEKVI-----LEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
Query: 656 VAP----VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAE---DSSSSEESDSEEEKTGL 708
+ P +R + P +P T P E D S+ +EE+ G
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGR 1279
Query: 709 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768
+ GK Q K +P GT LP + T +K + Q
Sbjct: 1280 VAP--KTVQEGKQPQTKMEGLP------SGTPQSLPKEDDKTTKTIKEQPQPP------- 1324
Query: 769 SDSEEAAASPAQVKTSVKKTQA---KANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
A P QV+ +KT+ K++ ++++ P + +S G
Sbjct: 1325 -----CTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG--------------- 1364
Query: 826 KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE---------SD 876
+ S+ L P+ +P+ K + + + +E S SS + S
Sbjct: 1365 -----YSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSI 1419
Query: 877 SEEEAETLAQVKPSGKT--HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS 934
E +A TLA K KT H++ P + + + T + +++ +
Sbjct: 1420 LEAQASTLADEKSEKKTQPHEVSPE-QPKDQEKTQSLSETLEITISEEEIKESQEERKDT 1478
Query: 935 SSEESDSDGEAPAAVTSAQVIKPPLIFVDP---NRSPAGPAATPAQAQAASTPRKARASE 991
++S D + S++ K FVD R P ++++ + P++ R +
Sbjct: 1479 FKKDSQQD------IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT- 1531
Query: 992 STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD 1051
S SSS E + ED + + IR ++ M ++ AS S++ I +
Sbjct: 1532 SVGSSSSDEYKQEDSQGSGE-EEDFIRKQIIEM----------SADEDASGSEDDEFIRN 1580
Query: 1052 GKKQEGPATQVSKKNPASLP--LTQAALKVLAQKASEAQPPVARTQPS--SGVDSAVGTL 1107
K+ +T+ KK +T + L +K+S + A + S D A
Sbjct: 1581 QLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDES 1640
Query: 1108 P------ATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS----------- 1150
P S +S + G LR+ K E+ S++ S+ +
Sbjct: 1641 PELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELE 1700
Query: 1151 -DSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAES 1190
+S + S ED +G+ S H TP + T V +S
Sbjct: 1701 MESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDS 1741
Score = 77.8 bits (190), Expect = 7e-14
Identities = 216/980 (22%), Positives = 335/980 (34%), Gaps = 178/980 (18%)
Query: 562 TAVAPAQEKSLGNIL-----QAKPTSSPAKGPPQKAGPVAV----QVKAEKPMDNSESSE 612
TA+ E L + Q S A+G P+ + P A + ++ +D+S +
Sbjct: 35 TAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPK 94
Query: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
+S D PA ++++ + P ++ +T S K + R + K+
Sbjct: 95 QSGRPPDPGR-PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMM 153
Query: 673 T---SPAGSSPAVAGGTQR--PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA 727
S + AV+ + P + S SE S E K V Q K G
Sbjct: 154 PGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGI------- 206
Query: 728 SVPVKGSLGQGTAPVLPGKTGP---TVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
+K L Q +P + GP + Q K S+ E+ P Q T
Sbjct: 207 ---IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ 263
Query: 785 VKKTQAKANPAA--ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
+T P A P K G+ V K PS KPP++ P +
Sbjct: 264 TPQTDHAKLPLQRDASRPQTKQADIVRGESV------KPSLPSPSKPPIQQPTPG----K 313
Query: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
PA P K+ Q GP + +PSG T P
Sbjct: 314 PPAQQPGHEKS-------QPGPAKPPA------------------QPSGLTK-------P 341
Query: 903 AKESPRKGAAPT-PPGKTGPSAAQAG--KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959
+ P P PPG T P A G K + SE+ S+ P A+ +PP
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALA-----QPPG 396
Query: 960 IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRT 1019
+ P + P GPA P Q TP K A + +S + PG
Sbjct: 397 VGKTPAQQP-GPAKPPTQQ--VGTP-KPLAQQPGLQSPAK--------------APGPTK 438
Query: 1020 NVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKK-NPASLPLTQ-AAL 1077
V P +I + + G +S++++ + GPA ++ PA P Q +
Sbjct: 439 TPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 1078 KVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQAT 1137
K +Q+ +PP + P+ G+ S Q S AK + + P P QQ+T
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS--AKPSAQQPSPAKPSAQQST 555
Query: 1138 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETL--VEETAAESSEDDV 1195
K + + + QG T+ P + TE L V E A ++ +
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK--TICPLCNTTELLLHVPEKANFNTCTEC 613
Query: 1196 VAPSQSLLSGYMTPGLTPA------NSQASKAT------------PKLDSSPSVSSTLAA 1237
SL P LT N Q +A PKL ++P +++ +
Sbjct: 614 QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673
Query: 1238 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1297
K P +Q + + AA PK +A P K G+P A +
Sbjct: 674 KSSPQPQQTSPKKDAA----PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS- 728
Query: 1298 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1357
L +P P E V + EQ++ V D D+P +
Sbjct: 729 --LSKPAPPKEPSVPS----------EQDKAPVAD-------------------DKP--K 755
Query: 1358 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG--SQGAKD 1415
P+ K A+ P+ S+ + +A+ +K + +K K S G K
Sbjct: 756 QPKMVKPTT-DLVSSSSATTKPDIPSSKVQSQAE-EKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 1416 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK 1475
P + + S+P E K +K + +KK++ KKA TK S P K
Sbjct: 814 SPFDSKAIPRPASDSKIISHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAK 869
Query: 1476 KKKK-------KKKTAEQTV 1488
K + TA QTV
Sbjct: 870 PMPKGSPTPPGPRPTAGQTV 889
Score = 60.8 bits (146), Expect = 9e-09
Identities = 136/686 (19%), Positives = 236/686 (34%), Gaps = 100/686 (14%)
Query: 73 AKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMK-EKAKAETEK 131
++KT V + + E+E + EAE + + + + + K E++K E +K
Sbjct: 1145 SQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDK 1204
Query: 132 AGKTGNSMPHPATGKTVAN-----------LLSGKSPR---KSAEPSANTTLVSETEEE- 176
A P P K + LL K P K P A T+ E + +
Sbjct: 1205 ASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDL 1264
Query: 177 -GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV-KASSVSTKESP 234
S G V+ + +T +EG PS P + K +TK
Sbjct: 1265 LKSQVQIAEEKLEGRVAPKTVQEGKQP------QTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
Query: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
+ P K V P +K E+E + S+ S + ++P G +S
Sbjct: 1319 EQPQPPCTAKPDQVEPG-----------KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
+ I + G+ + P + + K +E S SS + + E
Sbjct: 1368 DGI----------SSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES--- 1414
Query: 355 AAKALLQAKASGKTSQVGAASA-PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 413
++L+A+AS + P + SP + P KT + EE+ + S
Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQ---PKDQEKTQSLSETLEITISEEEIKES 1471
Query: 414 SEE------SDSEEEAPAQAKPSGKAPQV------RAASAPAKESPRKGAAPAPPRKTGP 461
EE DS+++ P+ K+ V R +ES +P P RK
Sbjct: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT 1531
Query: 462 AAAQVQVGK-QEEDSRSSSEESDSDREALAAMNA--------------AQVKPLGKSPQ- 505
+ + ++EDS+ S EE D R+ + M+A Q+K + S +
Sbjct: 1532 SVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTES 1591
Query: 506 VKPASTMGMGPL--GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTA 563
K T G G + GK + + W ++ + + +ES + E +
Sbjct: 1592 QKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
Query: 564 VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-----EKPMDNSESSEESSDSA 618
+ + G L+ T K + Q K E+P ES +S +
Sbjct: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDR 1711
Query: 619 DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGS 678
E +++ A+ P + + ++++ S K + +A + P
Sbjct: 1712 SRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPT-- 1769
Query: 679 SPAVAGGTQRPAEDSSSSEESDSEEE 704
EDSS EE EEE
Sbjct: 1770 -----------IEDSSEEEELREEEE 1784
Score = 52.4 bits (124), Expect = 3e-06
Identities = 190/988 (19%), Positives = 330/988 (33%), Gaps = 152/988 (15%)
Query: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
S P ++ + +A AK+ P T + P++ K + KAE K +
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-------PAAEKLEPKAEQAPTVKRTET 1023
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198
P K +L + P+K+ P T L + E + P G ++
Sbjct: 1024 EKKPPPIKDSKSLTA--EPQKAVLP---TKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
Query: 199 SSEDTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPG-------K 244
+E + + P + Q ++S + RK PAP
Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
Query: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304
V + K P K KK E+E ++ E E+ + + EKI
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV------KETLSMEKI------- 1185
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
P T + + K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 1186 -PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEK- 1239
Query: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
P P K AK A + ++ S+ +EE+
Sbjct: 1240 ----------------------KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
Query: 425 AQAKP----SGKAPQVRAASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVG 469
+ P GK PQ + P+ K + P PP P QV+ G
Sbjct: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPG 1335
Query: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
K++ + ++ S ++ KSPQ + + G +P +
Sbjct: 1336 KEKTEKEDDKSDTSSSQQP-------------KSPQGLSDTGYSSDGISSSLGEIP--SL 1380
Query: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
P + ++D S S+ESS SS ++ E ++ +IL+A+ ++ +
Sbjct: 1381 IPTDEKDILKGLKKD--SFSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSE 1433
Query: 590 QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
+K P V + K + ++S E+ + SEE + + K K + P +
Sbjct: 1434 KKTQPHEVSPEQPKDQEKTQSLSETLEITISEE-EIKESQEERKDTFKKDSQQDIPSSKD 1492
Query: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDS 701
++ + P + +S + +SP V +R + SSSS+E S
Sbjct: 1493 HKEKSEFVDDITTRREPYDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
Query: 702 EEEKTGLAVTVGQAKSVGKG-----------LQVKAASVPVKGSLGQGTAPVLPGKTGPT 750
EE+ + A G ++ +++ K +G + GK
Sbjct: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
Query: 751 VTQVKAEKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAK 803
+ ED+ S + D E SP K +++ R + +
Sbjct: 1612 TRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
Query: 804 GTISAPGKVVTAAAQAK-----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
+ K ++Q K P + + G +S+ + T+
Sbjct: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP 1731
Query: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPP 916
+ + +EDS SS E + + A+ +P G L P E S +
Sbjct: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEE 1784
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
+ +Q SSS++S D + A + K P N SP A+
Sbjct: 1785 LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTE 1840
Query: 977 QAQAASTPRKARASESTARSSSSESEDE 1004
+ + A+ + S + S S ES+ E
Sbjct: 1841 ELRQAAEMEELHRSSCSEYSPSIESDPE 1868
Score = 32.3 bits (72), Expect = 3.5
Identities = 61/288 (21%), Positives = 107/288 (37%), Gaps = 19/288 (6%)
Query: 380 ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG--KAPQVR 437
+ P + A GK G ++ +A K + S+ SS + E Q +P G + P +R
Sbjct: 3483 DMPTRSRRKARVGKYGDSM--TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR 3540
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
A E + +AP K G Q E DS + S + S
Sbjct: 3541 ARVDAKVEIIKHISAPEKTYKGGSLGCQT-----EADSDTQSPQYLSATSPPKDKKRPTP 3595
Query: 498 KPLGKSPQVKPASTMGMGPLGKGA-----GPVPPGKVGPATPSAQVGKWEEDSESSSEES 552
+G S ++ ST+ + P + P+ P G A SA V + + S +
Sbjct: 3596 LEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQK 3655
Query: 553 SDSSD-GEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
D +VP A A ++S+ + PT+ + P + K + M +S
Sbjct: 3656 VLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQY-TEGYTTKGSQTMTSS 3714
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV 656
+ ++ + + T Q+ + ++ +TNT A AK+
Sbjct: 3715 GAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKI 3762
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 124 bits (312), Expect = 5e-28
Identities = 317/1561 (20%), Positives = 537/1561 (34%), Gaps = 243/1561 (15%)
Query: 85 SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP-- 142
S+ SEEE A L + A+ PS M K + ++ K P P
Sbjct: 46 SQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS-MHRKQELDSSHPPKQSGRPPDPGR 104
Query: 143 ------ATGKTVANL-----LSGKSPRK-SAEPSANTTLVSETEEEGSVPAF-----GAA 185
+ +T L G+SP S + S + T + E + +P F +
Sbjct: 105 PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALS 164
Query: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
A +V+ D+ +S +ET + K V+ Q K + + P P +
Sbjct: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQ 223
Query: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305
G ++ P + +++PE+ +S G+ + P T A K+ R AS
Sbjct: 224 GPGRDPLQQDGTPKSISSQQPEK-IKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRDASR 280
Query: 306 P----AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 361
P A G+ P+ P + Q GKP + E+S + PA
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPA------ 333
Query: 362 AKASGKTSQVGAASAPAKESPRKGAAPA-PPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Q + P + P P PPG T P A+ + Q+ SE+ SE
Sbjct: 334 --------QPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSSE 384
Query: 421 EEAP-AQAKPSGKAPQVRAASAPAKESPRKGAAP----------APPRKTGPAAAQVQ-- 467
+ P A A+P G PAK ++ P +P + GP VQ
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 468 -----VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG---PLGK 519
+Q ++S++++ + A+ P P P G
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
Query: 520 GAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ-- 577
G+ PP + GPA PS Q + S + S + P+ P+ ++S + Q
Sbjct: 505 GSTKPPPQQPGPAKPSPQ--QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 578 -AKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES-----SEESSDSADSEEAPAAMTAAQ 631
KP P P K P K P+ N+ E+++ + +E +
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622
Query: 632 AKPALKIPQTKA-----CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 686
P + + K C K +APV Q K T+P ++ AV+ +
Sbjct: 623 FNPNPHLTEVKEWLCLNCQMK--RALGGDLAPVPSSPQPKLK----TAPVTTTSAVSKSS 676
Query: 687 QRPAEDSSSSEESDSEE---------------------EKTGLAVTVGQAKSVGKGLQVK 725
+P + S + + ++ + A +A S+ K K
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736
Query: 726 AASVPVKGSLGQGTAPVLPGK---------TGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
SVP + Q APV K T V+ A + D SS+ +S +EE
Sbjct: 737 EPSVPSE----QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 777 SP-----AQVKTSVKKTQAKANP----AAARAPSAKGTISAPGKVVTAAAQ------AKQ 821
P A+ S T K +P A R S IS PG + Q K+
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKK 852
Query: 822 RSPSKVKPPVRNPQNSTVLARG----PASVPSVGKAVATAAQAQTGPEED---SGSSEEE 874
P K + + ++ + +G P P+ G+ V T Q+ E+ S +
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSI 912
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAAL-----------------------APAKESPRKGA 911
+D+ + T Q +GK A++ AP K++P
Sbjct: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972
Query: 912 APT---PPGKTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
PT PP TG P+ + K++ ++E+ + E V + K P
Sbjct: 973 PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----P 1028
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 1023
P + A P +A + K+ EST +E P + V
Sbjct: 1029 PIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
Query: 1024 M----PTAH-PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALK 1078
+ PT H I + + S ++ D +K PA K +P +P ++ K
Sbjct: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-PAPSGPKASPMPVPTESSSQK 1147
Query: 1079 VLAQ---KASEAQPPVARTQPSSGVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPE 1132
K + Q +T+ + V ++ P T+ Q + +KL K K
Sbjct: 1148 TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASA 1207
Query: 1133 VQQATKAPES-----SDDSEDSSDSSSGSEEDGEGPQGAK---SAHTLGPTPSRTETLVE 1184
+Q+ PE ++ S + EE P+ K A T P + + L
Sbjct: 1208 LQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKS 1267
Query: 1185 ET-AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1243
+ AE + VAP + S ++ PK D +T K+ P
Sbjct: 1268 QVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD----KTTKTIKEQPQP 1323
Query: 1244 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1303
AKP Q KT ++ S T+ + K +G + S+ + S++ + +
Sbjct: 1324 PCTAKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPSL 1380
Query: 1304 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAAR 1357
P +E + + K D+ + S S KL + A+
Sbjct: 1381 IPTDEKDILKGLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426
Query: 1358 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1417
K +KK E VSPE+ K ++ + + E++ K S ++E
Sbjct: 1427 LADEKSEKKTQPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEER 1475
Query: 1418 EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1477
++ +K Q P SK K+KS+ ++E +++S ++ Q+K+
Sbjct: 1476 KDTFKK------DSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKR 1529
Query: 1478 K 1478
+
Sbjct: 1530 R 1530
Score = 119 bits (297), Expect = 3e-26
Identities = 316/1501 (21%), Positives = 506/1501 (33%), Gaps = 277/1501 (18%)
Query: 80 DPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSM 139
D IS SE+S+EE T K + G P ++ K ++ G + +
Sbjct: 177 DLISDSEASQEE------TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
Query: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
T K++++ K KS P + T+ P A P Q D+S
Sbjct: 231 QQDGTPKSISSQQPEKI--KSQPPGTGKPIQGPTQ----TPQTDHAKLPL-----QRDAS 279
Query: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP 259
T + D+ SVKP S S + P ++ P PGK PP
Sbjct: 280 RPQTK----QADIVRGESVKP-----SLPSPSKPPIQQ--PTPGK-------------PP 315
Query: 260 AKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA-PAKGTPGKGATPA 318
A+ + G E + PA +Q K L + + P PG PA
Sbjct: 316 AQ------------QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 319 PP-GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT--------- 368
P G A A QT + KP E P KAL Q GKT
Sbjct: 364 QPLGPAKPPAQQTGSEKPSS--------------EQPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 369 ---SQVGA----ASAPAKESPRKGAAPA--PPGKTGPAVAKAQ-AGKREEDSQSS----- 413
QVG A P +SP K P P + GP AQ AG + +Q +
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 414 -SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
S+ + P Q P+ PQ ++ P + P G+ PP++ GPA Q
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKPSPQ----- 522
Query: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532
+ S + S + A +A Q P S Q ST + G G P+ P V P+
Sbjct: 523 ---QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ---QSTKPVSQTGSGK-PLQPPTVSPS 575
Query: 533 T---PSAQVGKW-------EEDSESSSEESSDSSDGEVPTAVAPA--------------- 567
PS + K E E+++ ++ E T V
Sbjct: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635
Query: 568 ------QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE 621
+++LG L P+S P K PV K + + D+A +
Sbjct: 636 LCLNCQMKRALGGDLAPVPSSPQ---PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ 692
Query: 622 EAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR--VGTQAPRKAGTATSPAGSS 679
+ A + P +K P P +A AK P + AP K + S +
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSP-----SAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Query: 680 PAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 739
P ++P +++ S T + + +S + + + P+K + +
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE----EKTTPPLKTDSAKPS 803
Query: 740 APVLPG--KTGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKAN 793
P K P ++ DS+ S E+ P Q K KK Q K +
Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS 863
Query: 794 PAAARAPSAKGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVG 851
P P KG+ + PG TA Q+SP + R N + P S P+
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT-- 921
Query: 852 KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911
T + TG G+S S + T Q P H AP K++P
Sbjct: 922 ----TPQETVTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQ 972
Query: 912 APT---PPGKTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
PT PP TG P+ + K++ ++E+ + E V + K P
Sbjct: 973 PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----P 1028
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 1023
P + A P +A + K+ EST +E P + V
Sbjct: 1029 PIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
Query: 1024 M----PTAH-PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALK 1078
+ PT H I + + S ++ D +K PA K +P +P ++ K
Sbjct: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP-PAPSGPKASPMPVPTESSSQK 1147
Query: 1079 VLAQ---KASEAQPPVARTQPSSGVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPE 1132
K + Q +T+ + V ++ P T+ Q + +KL K K
Sbjct: 1148 TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASA 1207
Query: 1133 VQQATKAPESS-----DDSEDSSDSSSGSEEDGEGPQGAK---SAHTLGPTPSRTETLVE 1184
+Q+ PE ++ S + EE P+ K A T P + + L
Sbjct: 1208 LQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKS 1267
Query: 1185 ETA-AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1243
+ AE + VAP + S ++ PK D +T K+ P
Sbjct: 1268 QVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK----TTKTIKEQPQP 1323
Query: 1244 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1303
AKP Q KT ++ S T+ + K +G + S+ + S++ +
Sbjct: 1324 PCTAKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE------ 1376
Query: 1304 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1363
+ L+ + K ++ K+ +S ++ S P+
Sbjct: 1377 ---------------IPSLIPTDEKDILKGLKK------DSFSQESSPSSPS-------- 1407
Query: 1364 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1423
L E S+ + ST + K+++ +V ++ K +Q + E +
Sbjct: 1408 --DLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITIS- 1464
Query: 1424 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES--PSQKKKKKKK 1481
++E KE +++ K KDS+ PS K K+K
Sbjct: 1465 ---------------------------EEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS 1497
Query: 1482 K 1482
+
Sbjct: 1498 E 1498
Score = 95.9 bits (237), Expect = 3e-19
Identities = 249/1181 (21%), Positives = 408/1181 (34%), Gaps = 188/1181 (15%)
Query: 113 LGADL---PSSMKEKAK-AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
LG DL PSS + K K A S P P + + K+ EP
Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQ-ADSSSEDTSSSSDETDV-EGKPS----VKPAQ 222
LV + GS P+ A P S + A S D+ V + KP VKP
Sbjct: 706 LVKQPTLHGS-PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 223 --VKASSVSTK--------ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
V +SS +TK +S A + P K P + PP P +
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ---SFPPTGEKVSPFDSKAI 821
Query: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGT----------PGKGATPAPPGK 322
S+S+ + G S+ K +++ V+ P K P +P PPG
Sbjct: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881
Query: 323 ---AG-AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS-AP 377
AG V + ++ KP+E S S + + Q +GK GA+ +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 378 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 437
A P P ++GP QA + S K +G+AP
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP-----------KSTGQAPPAP 990
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
A S P K+ + AA K P A Q K+ E + DS A
Sbjct: 991 AKSIPVKKETKAPAA----EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP 1046
Query: 498 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-------------PSAQVGKWEE- 543
L KSP KP ST + G P T P+ + + +E
Sbjct: 1047 TKLEKSP--KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 544 -DSESSSEESSDSSDGEV-PTAVAPAQEKSLGNILQAKPTSSPAKGPPQ----KAGPVAV 597
++ + G++ AP+ K+ + + +S PPQ K V
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP--KKTNTTASAK 655
+ +AEK + E+ ++ E+ P +T Q + K+ + KA +K K
Sbjct: 1165 KTEAEKVI-----LEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
Query: 656 VAP----VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAE---DSSSSEESDSEEEKTGL 708
+ P +R + P +P T P E D S+ +EE+ G
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGR 1279
Query: 709 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768
+ GK Q K +P GT LP + T +K + Q
Sbjct: 1280 VAP--KTVQEGKQPQTKMEGLP------SGTPQSLPKEDDKTTKTIKEQPQPP------- 1324
Query: 769 SDSEEAAASPAQVKTSVKKTQA---KANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
A P QV+ +KT+ K++ ++++ P + +S G
Sbjct: 1325 -----CTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG--------------- 1364
Query: 826 KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE---------SD 876
+ S+ L P+ +P+ K + + + +E S SS + S
Sbjct: 1365 -----YSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSI 1419
Query: 877 SEEEAETLAQVKPSGKT--HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS 934
E +A TLA K KT H++ P + + + T + +++ +
Sbjct: 1420 LEAQASTLADEKSEKKTQPHEVSPE-QPKDQEKTQSLSETLEITISEEEIKESQEERKDT 1478
Query: 935 SSEESDSDGEAPAAVTSAQVIKPPLIFVDP---NRSPAGPAATPAQAQAASTPRKARASE 991
++S D + S++ K FVD R P ++++ + P++ R +
Sbjct: 1479 FKKDSQQD------IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT- 1531
Query: 992 STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD 1051
S SSS E + ED + + IR ++ M ++ AS S++ I +
Sbjct: 1532 SVGSSSSDEYKQEDSQGSGE-EEDFIRKQIIEM----------SADEDASGSEDDEFIRN 1580
Query: 1052 GKKQEGPATQVSKKNPASLP--LTQAALKVLAQKASEAQPPVARTQPS--SGVDSAVGTL 1107
K+ +T+ KK +T + L +K+S + A + S D A
Sbjct: 1581 QLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDES 1640
Query: 1108 P------ATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS----------- 1150
P S +S + G LR+ K E+ S++ S+ +
Sbjct: 1641 PELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELE 1700
Query: 1151 -DSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAES 1190
+S + S ED +G+ S H TP + T V +S
Sbjct: 1701 MESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDS 1741
Score = 77.8 bits (190), Expect = 7e-14
Identities = 216/980 (22%), Positives = 335/980 (34%), Gaps = 178/980 (18%)
Query: 562 TAVAPAQEKSLGNIL-----QAKPTSSPAKGPPQKAGPVAV----QVKAEKPMDNSESSE 612
TA+ E L + Q S A+G P+ + P A + ++ +D+S +
Sbjct: 35 TAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPK 94
Query: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
+S D PA ++++ + P ++ +T S K + R + K+
Sbjct: 95 QSGRPPDPGR-PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMM 153
Query: 673 T---SPAGSSPAVAGGTQR--PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA 727
S + AV+ + P + S SE S E K V Q K G
Sbjct: 154 PGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGI------- 206
Query: 728 SVPVKGSLGQGTAPVLPGKTGP---TVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
+K L Q +P + GP + Q K S+ E+ P Q T
Sbjct: 207 ---IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ 263
Query: 785 VKKTQAKANPAA--ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
+T P A P K G+ V K PS KPP++ P +
Sbjct: 264 TPQTDHAKLPLQRDASRPQTKQADIVRGESV------KPSLPSPSKPPIQQPTPG----K 313
Query: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
PA P K+ Q GP + +PSG T P
Sbjct: 314 PPAQQPGHEKS-------QPGPAKPPA------------------QPSGLTK-------P 341
Query: 903 AKESPRKGAAPT-PPGKTGPSAAQAG--KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959
+ P P PPG T P A G K + SE+ S+ P A+ +PP
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALA-----QPPG 396
Query: 960 IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRT 1019
+ P + P GPA P Q TP K A + +S + PG
Sbjct: 397 VGKTPAQQP-GPAKPPTQQ--VGTP-KPLAQQPGLQSPAK--------------APGPTK 438
Query: 1020 NVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKK-NPASLPLTQ-AAL 1077
V P +I + + G +S++++ + GPA ++ PA P Q +
Sbjct: 439 TPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 1078 KVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQAT 1137
K +Q+ +PP + P+ G+ S Q S AK + + P P QQ+T
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS--AKPSAQQPSPAKPSAQQST 555
Query: 1138 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETL--VEETAAESSEDDV 1195
K + + + QG T+ P + TE L V E A ++ +
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK--TICPLCNTTELLLHVPEKANFNTCTEC 613
Query: 1196 VAPSQSLLSGYMTPGLTPA------NSQASKAT------------PKLDSSPSVSSTLAA 1237
SL P LT N Q +A PKL ++P +++ +
Sbjct: 614 QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673
Query: 1238 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1297
K P +Q + + AA PK +A P K G+P A +
Sbjct: 674 KSSPQPQQTSPKKDAA----PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS- 728
Query: 1298 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1357
L +P P E V + EQ++ V D D+P +
Sbjct: 729 --LSKPAPPKEPSVPS----------EQDKAPVAD-------------------DKP--K 755
Query: 1358 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG--SQGAKD 1415
P+ K A+ P+ S+ + +A+ +K + +K K S G K
Sbjct: 756 QPKMVKPTT-DLVSSSSATTKPDIPSSKVQSQAE-EKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 1416 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK 1475
P + + S+P E K +K + +KK++ KKA TK S P K
Sbjct: 814 SPFDSKAIPRPASDSKIISHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAK 869
Query: 1476 KKKK-------KKKTAEQTV 1488
K + TA QTV
Sbjct: 870 PMPKGSPTPPGPRPTAGQTV 889
Score = 60.8 bits (146), Expect = 9e-09
Identities = 136/686 (19%), Positives = 236/686 (34%), Gaps = 100/686 (14%)
Query: 73 AKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMK-EKAKAETEK 131
++KT V + + E+E + EAE + + + + + K E++K E +K
Sbjct: 1145 SQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDK 1204
Query: 132 AGKTGNSMPHPATGKTVAN-----------LLSGKSPR---KSAEPSANTTLVSETEEE- 176
A P P K + LL K P K P A T+ E + +
Sbjct: 1205 ASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDL 1264
Query: 177 -GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV-KASSVSTKESP 234
S G V+ + +T +EG PS P + K +TK
Sbjct: 1265 LKSQVQIAEEKLEGRVAPKTVQEGKQP------QTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
Query: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
+ P K V P +K E+E + S+ S + ++P G +S
Sbjct: 1319 EQPQPPCTAKPDQVEPG-----------KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
+ I + G+ + P + + K +E S SS + + E
Sbjct: 1368 DGI----------SSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES--- 1414
Query: 355 AAKALLQAKASGKTSQVGAASA-PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 413
++L+A+AS + P + SP + P KT + EE+ + S
Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQ---PKDQEKTQSLSETLEITISEEEIKES 1471
Query: 414 SEE------SDSEEEAPAQAKPSGKAPQV------RAASAPAKESPRKGAAPAPPRKTGP 461
EE DS+++ P+ K+ V R +ES +P P RK
Sbjct: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT 1531
Query: 462 AAAQVQVGK-QEEDSRSSSEESDSDREALAAMNA--------------AQVKPLGKSPQ- 505
+ + ++EDS+ S EE D R+ + M+A Q+K + S +
Sbjct: 1532 SVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTES 1591
Query: 506 VKPASTMGMGPL--GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTA 563
K T G G + GK + + W ++ + + +ES + E +
Sbjct: 1592 QKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
Query: 564 VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-----EKPMDNSESSEESSDSA 618
+ + G L+ T K + Q K E+P ES +S +
Sbjct: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDR 1711
Query: 619 DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGS 678
E +++ A+ P + + ++++ S K + +A + P
Sbjct: 1712 SRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPT-- 1769
Query: 679 SPAVAGGTQRPAEDSSSSEESDSEEE 704
EDSS EE EEE
Sbjct: 1770 -----------IEDSSEEEELREEEE 1784
Score = 52.4 bits (124), Expect = 3e-06
Identities = 190/988 (19%), Positives = 330/988 (33%), Gaps = 152/988 (15%)
Query: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
S P ++ + +A AK+ P T + P++ K + KAE K +
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-------PAAEKLEPKAEQAPTVKRTET 1023
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198
P K +L + P+K+ P T L + E + P G ++
Sbjct: 1024 EKKPPPIKDSKSLTA--EPQKAVLP---TKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
Query: 199 SSEDTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPG-------K 244
+E + + P + Q ++S + RK PAP
Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
Query: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304
V + K P K KK E+E ++ E E+ + + EKI
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV------KETLSMEKI------- 1185
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
P T + + K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 1186 -PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEK- 1239
Query: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
P P K AK A + ++ S+ +EE+
Sbjct: 1240 ----------------------KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
Query: 425 AQAKP----SGKAPQVRAASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVG 469
+ P GK PQ + P+ K + P PP P QV+ G
Sbjct: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPG 1335
Query: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
K++ + ++ S ++ KSPQ + + G +P +
Sbjct: 1336 KEKTEKEDDKSDTSSSQQP-------------KSPQGLSDTGYSSDGISSSLGEIP--SL 1380
Query: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
P + ++D S S+ESS SS ++ E ++ +IL+A+ ++ +
Sbjct: 1381 IPTDEKDILKGLKKD--SFSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSE 1433
Query: 590 QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
+K P V + K + ++S E+ + SEE + + K K + P +
Sbjct: 1434 KKTQPHEVSPEQPKDQEKTQSLSETLEITISEE-EIKESQEERKDTFKKDSQQDIPSSKD 1492
Query: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDS 701
++ + P + +S + +SP V +R + SSSS+E S
Sbjct: 1493 HKEKSEFVDDITTRREPYDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
Query: 702 EEEKTGLAVTVGQAKSVGKG-----------LQVKAASVPVKGSLGQGTAPVLPGKTGPT 750
EE+ + A G ++ +++ K +G + GK
Sbjct: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
Query: 751 VTQVKAEKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAK 803
+ ED+ S + D E SP K +++ R + +
Sbjct: 1612 TRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
Query: 804 GTISAPGKVVTAAAQAK-----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
+ K ++Q K P + + G +S+ + T+
Sbjct: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP 1731
Query: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPP 916
+ + +EDS SS E + + A+ +P G L P E S +
Sbjct: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEE 1784
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
+ +Q SSS++S D + A + K P N SP A+
Sbjct: 1785 LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTE 1840
Query: 977 QAQAASTPRKARASESTARSSSSESEDE 1004
+ + A+ + S + S S ES+ E
Sbjct: 1841 ELRQAAEMEELHRSSCSEYSPSIESDPE 1868
Score = 32.3 bits (72), Expect = 3.5
Identities = 61/288 (21%), Positives = 107/288 (37%), Gaps = 19/288 (6%)
Query: 380 ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG--KAPQVR 437
+ P + A GK G ++ +A K + S+ SS + E Q +P G + P +R
Sbjct: 3483 DMPTRSRRKARVGKYGDSM--TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR 3540
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
A E + +AP K G Q E DS + S + S
Sbjct: 3541 ARVDAKVEIIKHISAPEKTYKGGSLGCQT-----EADSDTQSPQYLSATSPPKDKKRPTP 3595
Query: 498 KPLGKSPQVKPASTMGMGPLGKGA-----GPVPPGKVGPATPSAQVGKWEEDSESSSEES 552
+G S ++ ST+ + P + P+ P G A SA V + + S +
Sbjct: 3596 LEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQK 3655
Query: 553 SDSSD-GEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
D +VP A A ++S+ + PT+ + P + K + M +S
Sbjct: 3656 VLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQY-TEGYTTKGSQTMTSS 3714
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV 656
+ ++ + + T Q+ + ++ +TNT A AK+
Sbjct: 3715 GAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKI 3762
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 123 bits (308), Expect = 2e-27
Identities = 262/1279 (20%), Positives = 439/1279 (34%), Gaps = 191/1279 (14%)
Query: 106 ASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSA 165
A + S D + + +A + G SMP G+ G +P S S
Sbjct: 881 AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGE-------GSTPLTSMPDST 933
Query: 166 NTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKA 225
+ SE + P + A + +++E TS + T EG + V
Sbjct: 934 TPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTS-TPSEGTTPLTSTPVSH 992
Query: 226 SSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPA 285
+ V+ E+ P T P A+ P + + EGS P
Sbjct: 993 TLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMP---TSTPSEGSTPLTRMPV 1049
Query: 286 GTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE 345
T + V +SE ++ TP +TP + A +S T A + + SE
Sbjct: 1050 ST-TMVASSE--------TSTLSTTPADTSTPVTT-YSQASSSSTTADGTSMPTSTYSEG 1099
Query: 346 SSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP----------APPGKTG 395
S+ + + ++ ++AS ++ S P S ++P +PP +
Sbjct: 1100 STPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGT 1159
Query: 396 PAVAKAQAGKR----EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 451
+A E + S+ DS+ + + S P S P +P + +
Sbjct: 1160 TPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTS-TPGERS 1218
Query: 452 APA---PPRKTGPAAAQVQVGKQEEDSRS-----SSEESDSDREALAAMNAAQVKPLGKS 503
P P R T A+++ S S+E S S A G +
Sbjct: 1219 TPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGST 1278
Query: 504 --PQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVP 561
+ ++T+ P P GP S +V +E +S +S S+G P
Sbjct: 1279 LLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTP 1338
Query: 562 TAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE 621
P + + A+ + + P+DNS S+++ S
Sbjct: 1339 LTSIPVNTTLVASS--------------------AISILSTTPVDNSTPVTTSTEACSSP 1378
Query: 622 EAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
+ + P+ + P T S++ + + GT ++ A SSP
Sbjct: 1379 TTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPT 1438
Query: 682 VAGG----TQRPAEDSS-------SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVP 730
A G T P+E + S+ + E T V V V ++ P
Sbjct: 1439 TAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTP 1498
Query: 731 VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK-TQ 789
+G+ A P + +T + S ++ S+ + +PA T V +Q
Sbjct: 1499 AEGT---SIAISTPSEGSTALTSIPV-----STTTVASSEINSLSTTPAVTSTPVTTYSQ 1550
Query: 790 AKANPAAARAPSAKGTISAPGK------------VVTAAAQAKQRSP--SKVKPPVRNPQ 835
A ++P A S + + + G VV++ A +P SK +
Sbjct: 1551 ASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEA 1610
Query: 836 NSTVLARGPA---SVPSVGKAVATAAQAQTGP---EEDSGSSEEESDSEEEAETLAQVKP 889
+S+ A G + S PS G + T+ T P E S S DS T +V
Sbjct: 1611 SSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSS 1670
Query: 890 S----------------GKT--HQIRAALAPAKESPRKGAAPTP-----PGKTGPSAAQA 926
S G+T I P S + TP P T A +
Sbjct: 1671 SPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSS 1730
Query: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
+ S + S+G P +TS V P++ + + A P T STP
Sbjct: 1731 PTTSEGTSMPNSTPSEGTTP--LTSIPVSTTPVLSSEASTLSATPIDT-------STP-- 1779
Query: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 1046
+ ST +SS + + IP T L+ G+ T + + P +H +A + E+
Sbjct: 1780 --VTTSTEATSSPTTAEGTSIP-TSTLSEGM-TPLTSTPVSHTLVA----------NSEA 1825
Query: 1047 SRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGT 1106
S +S T V +P ++ A+ S +A + PS G +A+ +
Sbjct: 1826 STLS--------TTPVDSNSPVVTSTAVSSSPTPAEGTS-----IATSTPSEG-STALTS 1871
Query: 1107 LPATSPQSTSVQAKGTNKL-RKPKLPEVQQATKAP-ESSDDSEDSSDSSSGSEEDGEGP- 1163
+P + +T+V + TN L P + T A SS + D S + + +G P
Sbjct: 1872 IPVS---TTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPL 1928
Query: 1164 ---------QGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1214
+ +TL T + T T V T +++S A S+ + + G TP
Sbjct: 1929 TSIPVSTTTVASSEINTLSTTLADTRTPV-TTYSQASSSPTTADGTSMPTPAYSEGSTPL 1987
Query: 1215 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1274
S T + S S ST P G SP T G + +TP +
Sbjct: 1988 TSMPLSTTLVVSSEASTLST-----TPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSER 2042
Query: 1275 RKPKKGAGNPQASTLALQS 1293
P AG P ++TL + S
Sbjct: 2043 TTPL--AGMPVSTTLVVSS 2059
Score = 113 bits (283), Expect = 1e-24
Identities = 277/1384 (20%), Positives = 468/1384 (33%), Gaps = 154/1384 (11%)
Query: 81 PISTSESSEEEEEAEAETAKATPR---LASTNSSVLGADLPSSMKEKAKAETEKAGKTGN 137
P ST ++S + +TP ++ST + V A LPS +A T K
Sbjct: 130 PSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSF-----EAYTSLTYKVDM 184
Query: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
S P L + S +TT+ T EGS P A V++ +A
Sbjct: 185 STP----------LTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAI 234
Query: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP---APGKVGDVTPQVKG 254
+ S + + S P + S+S +P+ + P P V V
Sbjct: 235 TLLTTPVEISTPVTISAQASSSPTTAEGPSLS-NSAPSGGSTPLTRMPLSVMLVVSSEAS 293
Query: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
P S + + E T + + S + A++ P +
Sbjct: 294 TLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMST 353
Query: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSS------EESSDSEEETPAAKALLQAKASGKT 368
+ P + V + T+ +E++S E S P + L+ + + T
Sbjct: 354 LSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTT 413
Query: 369 SQV------------GAASAP--------AKESPRKGAAP--APPGKTGPAVAKAQAGKR 406
S + A+S+P A +P +G+ P + P T P +
Sbjct: 414 STIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVAS------- 466
Query: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
E S S+ DS+ + + S P S P +P +G+ P T + + +
Sbjct: 467 SEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPT-STPSEGSTPL----TSMSVSTM 521
Query: 467 QVGKQEEDSRSSSE-ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 525
V E + S++ ++ + + +++ P G S P ST G PV
Sbjct: 522 PVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTS---IPTSTPSEGSTPLTNMPVS 578
Query: 526 PGKV--GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS 583
V A+ ++ ++S E+S SS T++ + G + + S+
Sbjct: 579 TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVST 638
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP--QT 641
+ + V + P+ S + SS +A+ P + + P +P T
Sbjct: 639 TLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTT 698
Query: 642 KACPKKTNTTASAKV---APVRVGTQAPRKAGTA--------TSPAGSSPAVAGGTQRPA 690
+ +T ++ V PV T+A TA T GS+P + +
Sbjct: 699 LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTL 758
Query: 691 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 750
SS + + T +T S + S+P+ S +P+L T
Sbjct: 759 LTSSEASTLSTTPLDTSTHITTSTEASCSP-TTTEGTSMPI--STPSEGSPLL---TSIP 812
Query: 751 VTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPG 810
V+ E S S DS + +V +S + + P + + S P
Sbjct: 813 VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPV 872
Query: 811 K---VVTAAAQAKQRSPSKVKPPVRN---PQNSTVLARG---PASVPSVGKAVATAAQAQ 861
V T+A +P PV N ++S + G P S P G T+
Sbjct: 873 STTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDS 932
Query: 862 TGPEEDSGSSEEESDSEEEAETLAQVKPSGK-THQIRAALAPAKESPRKGAAPTPPGKTG 920
T P SSE + S +T V S + T A + + TP T
Sbjct: 933 TTPVV---SSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTP 989
Query: 921 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA--ATPAQA 978
S + S S+ DS+ TS + PP + + P+ +TP
Sbjct: 990 VSHTLVANSEASTLSTTPVDSN---TPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTR 1046
Query: 979 QAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPT------AHPRIA 1032
ST A +SE++ S++ V +Q + + +MPT + P +
Sbjct: 1047 MPVSTTMVA-SSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTS 1105
Query: 1033 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1092
S SS+ S+ + P T + +S P T + SE P+A
Sbjct: 1106 VPVSTRLVVSSEASTLSTTPVDTSIPVT--TSTEASSSPTTAEGTSIPTSPPSEGTTPLA 1163
Query: 1093 RTQPSSG--VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1150
S+ V S TL +T+P + Q + + P P + T P S+ +
Sbjct: 1164 SMPVSTTLVVSSEANTL-STTPVDSKTQVATSTEASSP--PPTAEVTSMPTSTPGERSTP 1220
Query: 1151 DSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG 1210
+S P + A TL +P T T V T+AE+S A SL + + G
Sbjct: 1221 LTSMPVRHT---PVASSEASTLSTSPVDTSTPV-TTSAETSSSPTTAEGTSLPTSTTSEG 1276
Query: 1211 LTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTT 1270
T S T L +SP S+ L D G P E +S T
Sbjct: 1277 STLLTSIPVSTT--LVTSPEASTLLTTPVDTKG--------------PVVTSNEVSSSPT 1320
Query: 1271 PQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKV 1330
P +G P ++ ++ +T P+N V +S + +L+ V
Sbjct: 1321 ------PAEGTSMPTSTYSEGRTPLTSI------PVNTTLVASSAISILSTTPVDNSTPV 1368
Query: 1331 VDTTKESSRKGWESRKRKLSGDQPAARTPRSK---KKKKLGAGEGGEASVSPEKTSTTSK 1387
+T+ S + + TP + + + E S +P TST
Sbjct: 1369 TTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGT 1428
Query: 1388 GKAK 1391
A+
Sbjct: 1429 TSAE 1432
Score = 109 bits (273), Expect = 2e-23
Identities = 233/1204 (19%), Positives = 413/1204 (34%), Gaps = 140/1204 (11%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
ST ++ E + TA+AT L ST S G+ ++M T +++P
Sbjct: 362 STLVTTSTEPSSLPTTAEATSMLTSTLSE--GSTPLTNMPVSTILVASSEASTTSTIP-- 417
Query: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD----- 197
KT S S S + +T++ + T EGS P V++ +A
Sbjct: 418 VDSKTFVTTASEAS--SSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTT 475
Query: 198 --------SSSEDTSSSSDETDVEGKPSVKPAQ----VKASSVSTKESPARKAAPAPGKV 245
++S + SSS +V P+ P++ + + SVST + +A+
Sbjct: 476 PVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTP 535
Query: 246 GDVTPQVKGGALPPAKRAKKPEEES---ESSEEGSESEEEAPAGTR----------SQVK 292
D + V + + + PE S + EGS P TR S
Sbjct: 536 VDTSTPVTTSS-EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTP 594
Query: 293 ASEKILQVRAASAPAKGTPGKGA---TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDS 349
A ++ A + T +G T + + S + + SE+S+ ++
Sbjct: 595 ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPV 654
Query: 350 EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREED 409
+ TP + +A+ ++ S P + +G+ P + + E
Sbjct: 655 DSNTPVTTS---TEATSSSTTAEGTSMPT-STYTEGSTPLTSMPVNTTLVAS-----SEA 705
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP---APPRKTGPAAAQV 466
S S+ D+ + S AS P +P +G+ P P KT +++
Sbjct: 706 STLSTTPVDTSTPVTTSTEASSSPTTADGASMPT-STPSEGSTPLTSMPVSKTLLTSSEA 764
Query: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP-------ASTMGMGPLGK 519
S+ + ++ P+ + P + T P
Sbjct: 765 STLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEAS 824
Query: 520 GAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK 579
P P T S +V +E +S +S S+G P P + +
Sbjct: 825 TLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAIST 884
Query: 580 PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP 639
+++P V P+ NS + S +++ P + + P +P
Sbjct: 885 LSTTP--------------VDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMP 930
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 699
+ P ++ + PV T T ++ A SSP A GT P S
Sbjct: 931 DS-TTPVVSSEARTLSATPVDTSTPV-----TTSTEATSSPTTAEGTSIPTSTPSEGTTP 984
Query: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE-- 757
+ + V +A ++ V + + + P G + PT T +
Sbjct: 985 LTSTPVSHTLVANSEASTLST-TPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTP 1043
Query: 758 --KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTA 815
+ S + S++ + +PA T V + A++ + +A GT S P +
Sbjct: 1044 LTRMPVSTTMVASSETSTLSTTPADTSTPV----TTYSQASSSSTTADGT-SMPTSTYSE 1098
Query: 816 AAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 875
+ P + V + ++ S+P V T+ +A + P G+S S
Sbjct: 1099 GSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIP-----VTTSTEASSSPTTAEGTSIPTS 1153
Query: 876 DSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS- 934
E LA + + L + E+ P ++ +A +
Sbjct: 1154 PPSEGTTPLASM-------PVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEV 1206
Query: 935 SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ-AQAASTPRKARASEST 993
+S + + GE +TS V P+ + + P T +A T +E T
Sbjct: 1207 TSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGT 1266
Query: 994 ARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG-ASSSKESSRISDG 1052
+ +S+ SE ++ + + T +VT P A + G +S E S S
Sbjct: 1267 SLPTSTTSEGSTLLTSIP-----VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVS--SSP 1319
Query: 1053 KKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA--T 1110
EG + S + PLT PV T +S S + T P +
Sbjct: 1320 TPAEGTSMPTSTYSEGRTPLTSI--------------PVNTTLVASSAISILSTTPVDNS 1365
Query: 1111 SPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAH 1170
+P +TS +A + P + T P +S+ SE ++ + S P + A
Sbjct: 1366 TPVTTSTEACSS--------PTTSEGTSMP-NSNPSEGTTPLT--SIPVSTTPVVSSEAS 1414
Query: 1171 TLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPS 1230
TL TP T T T+AE++ A S+ + + G TP S TP +S S
Sbjct: 1415 TLSATPVDTST-PGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAS 1473
Query: 1231 VSST 1234
ST
Sbjct: 1474 TLST 1477
Score = 108 bits (270), Expect = 4e-23
Identities = 247/1307 (18%), Positives = 437/1307 (33%), Gaps = 185/1307 (14%)
Query: 79 SDPISTSE--SSEEEEEAEAETAKATP-----RLASTNSSVLGADLPSSMKEKAKAETEK 131
S P+ST+ SSE + +TP +++S+ ++ G+ +P+S + +
Sbjct: 1871 SIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTS 1930
Query: 132 AGKTGNSMPHPATGKTVANLLSGKSP-----RKSAEPSA--NTTLVSETEEEGSVPAFGA 184
+ ++ L ++P + S+ P+ T++ + EGS P
Sbjct: 1931 IPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSM 1990
Query: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK 244
+V + +A + S +S + S P +S+ T +P+ + P G
Sbjct: 1991 PLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTS-TPSERTTPLAGM 2049
Query: 245 VGDVTPQV--KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRA 302
T V +G L K + + + S + E + + + S + +
Sbjct: 2050 PVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPL 2109
Query: 303 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD-SEEETPAAKALLQ 361
++ P + P V + T+ +E +S ++S S+ TP L
Sbjct: 2110 STTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTP-----LT 2164
Query: 362 AKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421
+ T +A + +P + P +A++ + S + SE
Sbjct: 2165 SMPVSTTVVASSAISTLSTTPVDTSTPVTNS------TEARSSPTTSEGTSMPTSTPSEG 2218
Query: 422 EAPAQAKPSGKAPQVRA-----------ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGK 470
P + P P V + S P S ++P T + + G
Sbjct: 2219 STPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGT 2278
Query: 471 --------------QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
E S S+ DS+ + A+ P + + P ST G
Sbjct: 2279 TPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSM-PTSTSSEGN 2337
Query: 517 LGKGAGPV----------------PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEV 560
PV P P T +Q G ++ +S +S S+G
Sbjct: 2338 TPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGST 2397
Query: 561 PTAVAPAQE--------------------------KSLGNILQAKPTSSPAKGPPQKAGP 594
P P ++ + A+ TS P P + P
Sbjct: 2398 PLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP 2457
Query: 595 VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASA 654
+A + P+ +SE+ S+ D+ T A + P + P T + S
Sbjct: 2458 LASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTA--EDIVVPISTASEGST 2515
Query: 655 KVAPVRVGTQ---APRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 711
+ + V T +P + +T+P S+ V +S+E S S G ++
Sbjct: 2516 LLTSIPVSTTPVASPEASTLSTTPVDSNSPVV----------TSTEISSSATSAEGTSMP 2565
Query: 712 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDS 771
L+ S S T P T VT E S S D+
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTT----STETSSSPTTAKDT 2621
Query: 772 EEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK--- 828
++P++V TS+ P A+ S T + + + SP+ +
Sbjct: 2622 SMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSS 2681
Query: 829 PPVRNP-----------QNSTVLARGPASVPS-----VGKAVATAAQAQTGPEEDSGSSE 872
P P ++T+LA AS S V T+A+A + P G+S
Sbjct: 2682 MPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM 2741
Query: 873 EESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS 932
S + + L + S + A + A + P T A+ + +
Sbjct: 2742 RISTPSDGSTPLTSILVS----TLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEV 2797
Query: 933 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 992
S + S+ P +TS V P+ + P T + +T KA +S +
Sbjct: 2798 TSMPTSTPSETSTP--LTSMPVNHTPVASSEAGTLSTTPVDT---STPVTTSTKASSSPT 2852
Query: 993 TARS----SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSR 1048
TA S+ SE ++ + P T V + + P + ++S E S
Sbjct: 2853 TAEGIVVPISTASEGSTLLTS----IPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGS- 2907
Query: 1049 ISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLP 1108
S EG + +S + S PLT + + SEA T ++ VD+
Sbjct: 2908 -SSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEAS-----TLSTTPVDT------ 2955
Query: 1109 ATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1168
+P +TS +A + P + T P S+ + +S P +
Sbjct: 2956 -RTPVTTSAEASSS--------PTTAEGTSMPISTPGERRTPLTSMSV---STMPVASSE 3003
Query: 1169 AHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATP-KLDS 1227
A TL TP+ T T V T+ E+S A + + G TP S TP +
Sbjct: 3004 ASTLSRTPADTSTPV-TTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPE 3062
Query: 1228 SPSVSSTLAAKDDP---DGKQEAKPQQAAGMLSPKTGGKEAASGTTP 1271
+ ++S+T + P + + P A G P + E G+TP
Sbjct: 3063 ASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSE---GSTP 3106
Score = 103 bits (258), Expect = 9e-22
Identities = 250/1311 (19%), Positives = 436/1311 (33%), Gaps = 157/1311 (11%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
S S+ + +EA T TP ST ++ A SS + +G S P
Sbjct: 220 SMPASTMKVASSEAITLLTTPVEISTPVTI-SAQASSSPTTAEGPSLSNSAPSGGSTPLT 278
Query: 143 ATGKTVANLLSGKSPRKSAEPSAN-------------------TTLVSETEEEGSVPAFG 183
+V ++S ++ S P+A T++ + T EGS P
Sbjct: 279 RMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTS 338
Query: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
A V+ + + S +S +PS P +A+S+ T
Sbjct: 339 TPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNM 398
Query: 244 KVGDV---TPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
V + + + + P SE+S + +E+ + A T + + S + +
Sbjct: 399 PVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIA-TSTPSEGSTPLTSM 457
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSE-SSSEESSDSEEETP----- 354
++ P + + P V + T+A +E +S S+ SE TP
Sbjct: 458 PVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMS 517
Query: 355 -AAKALLQAKASG-KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK------- 405
+ + ++AS T+ V ++ S ++ P G + P ++
Sbjct: 518 VSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPV 577
Query: 406 ------REEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKT 459
E S +S+ +DS ++ S + S P +G +
Sbjct: 578 STRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVS 637
Query: 460 GPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL-- 517
A + S+ + EA ++ A+ + S + ++ + P+
Sbjct: 638 TTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697
Query: 518 -------GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK 570
P P T S + ++ +S +S S+G P P +
Sbjct: 698 TLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSK- 756
Query: 571 SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAP------ 624
+L + S+ + P + + +A +E + S SE +P
Sbjct: 757 ---TLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGT-SMPISTPSEGSPLLTSIP 812
Query: 625 ---AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
+T+ +A P P T+T S+ P GT P T+T G +P
Sbjct: 813 VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAE-GTSMP----TSTYSEGRTPL 867
Query: 682 VAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
+ +S+ + T VT ++ + S+P + G+G+ P
Sbjct: 868 TSMPVSTTLVATSAISTLSTTPVDTSTPVT-NSTEARSSPTTSEGTSMPT-STPGEGSTP 925
Query: 742 V--LPGKTGPTV-TQVKAEKQEDSESSEEESDSEEAAASPAQVK-TSVKKTQAKANPAAA 797
+ +P T P V ++ + ++S + S EA +SP + TS+ +
Sbjct: 926 LTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPL 985
Query: 798 RAPSAKGTISAPGKVVT-AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 856
+ T+ A + T + +P +P + P S PS G T
Sbjct: 986 TSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLT 1045
Query: 857 AAQAQT---GPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAP 913
T E S S +D+ T +Q S T A + +
Sbjct: 1046 RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTT-----ADGTSMPTSTYSEGS 1100
Query: 914 TPPGKTGPSAAQAGKQDDSGSSSEESD------SDGEAPAAVTSAQVIKPPLIFVDPNRS 967
TP S + S S+ D + EA ++ T+A+ P S
Sbjct: 1101 TPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP-------TS 1153
Query: 968 PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 1027
P TP + ST +SE+ S++ V +T+ +P V +MPT+
Sbjct: 1154 PPSEGTTPLASMPVSTTLVV-SSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTS 1212
Query: 1028 HP--RIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKAS 1085
P R P SM + SS S T + S P+T +A + S
Sbjct: 1213 TPGERSTPLTSMPVRHTPVASSEAS---------TLSTSPVDTSTPVTTSA------ETS 1257
Query: 1086 EAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD 1145
+ T + S TL + P ST++ PE P +
Sbjct: 1258 SSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTS----------PEASTLLTTPVDTKG 1307
Query: 1146 SEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRT----ETLVEETAAE-------SSEDD 1194
+S+ S S EG S ++ G TP + TLV +A +
Sbjct: 1308 PVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTP 1367
Query: 1195 VVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSP--------SVSSTLAAKDDPDGKQE 1246
V +++ S + G + NS S+ T L S P S +STL+A P
Sbjct: 1368 VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSA--TPVDTST 1425
Query: 1247 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG-------AGNPQASTLA 1290
A SP T + +TP + + P K N +ASTL+
Sbjct: 1426 PGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLS 1476
Score = 101 bits (251), Expect = 6e-21
Identities = 261/1281 (20%), Positives = 425/1281 (33%), Gaps = 178/1281 (13%)
Query: 67 EDAALQAKKTRVSDPISTS-ESSEEEEEAEAETAK-ATPRLASTN-SSVLGADLPSSMKE 123
E + L S P++TS E+S AE + + +TP ST +S+L + LP + E
Sbjct: 2708 EASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSE 2767
Query: 124 KAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEE-GSVPAF 182
+ T T P T T A+ SP + S T+ SET S+P
Sbjct: 2768 ASTVST-----TAVDTSIPVTTSTEAS----SSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818
Query: 183 G---AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAA 239
A+++ G +S D+S+ T+S T P+ V S +++ S +
Sbjct: 2819 HTPVASSEAGTLSTTPVDTSTPVTTS----TKASSSPTTAEGIVVPISTASEGSTLLTSI 2874
Query: 240 PAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEA-----PAGTRSQVKAS 294
P TP A + +S EGS S A P T S+V S
Sbjct: 2875 PV-----STTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEV--S 2927
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE-SSDSEEET 353
+ + ++ P G+ + P V + +A +E +S S+ E T
Sbjct: 2928 TPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987
Query: 354 PAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 413
P + + ++ P S + P + P +A SS
Sbjct: 2988 PL-------------TSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEA--------SS 3026
Query: 414 SEESDSEEEAPAQAKPSGKAP--QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 471
S + P G P + ++ P + P P +V
Sbjct: 3027 SPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSS 3086
Query: 472 EEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA-STMGMGPLGKGAGPVPPGKVG 530
+ +S + E + P+ +P A ST+ P+
Sbjct: 3087 PTPAEGTSMPISTYSEGSTPLTGV---PVSTTPVTSSAISTLSTTPVDTST--------- 3134
Query: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE----KSLGNILQAKP------ 580
P T S + SE +S +S S+G P P S + L A P
Sbjct: 3135 PVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTP 3194
Query: 581 ---------------TSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
TS P P + P+ + P+ +SE+S S+ DS
Sbjct: 3195 VTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLT 3254
Query: 626 AMTAAQAKPAL--------KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT---- 673
T A + P P + P + ++ VA T + A T+T
Sbjct: 3255 TSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTT 3314
Query: 674 -SPAGSSPAVAGGTQRPAEDSS-----------------SSEES--DSEEEKTGLAVTVG 713
S A SSP +A GT P S SSE S + T VT
Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374
Query: 714 QAKSVGKGLQVKAASVPVKGSLGQGTAPV--LPGKTGPTV-TQVKAEKQEDSESSEEESD 770
S+ + S+P S +GT P+ +P T P V ++V +S+ +
Sbjct: 3375 TEASLSP-TTAEGTSIPT-SSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTT 3432
Query: 771 SEEAAASP--AQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
S EA++SP A+ + T ++ + + P + +++ + +P
Sbjct: 3433 STEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTS 3492
Query: 829 PPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP---EEDSGSSEEESDSEEEAETLA 885
P + + + P S G T T P E S S DS + +
Sbjct: 3493 SPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSS 3552
Query: 886 QVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEA 945
Q S T Q+ +P +G++ S+ + S S+ D
Sbjct: 3553 QASSSPATLQVTTM---RMSTPSEGSSSLTTMLL--SSTYVTSSEASTPSTPSVDRSTPV 3607
Query: 946 PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDED 1005
+ S PP + P +P+ +TP ST SE+ S+
Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPS-EVSTPLTIMPVST-TSVTISEAGTASTLPVDTSTP 3665
Query: 1006 VIPATQCLTPGIRTNVVTMPT------AHPRIAPKASMAGASSSKESSRISDGKKQEGPA 1059
VI +TQ + + TMP + P S +SS+ S+ + P
Sbjct: 3666 VITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPV 3725
Query: 1060 TQVSKKNPASLPLTQAALKV--------LAQKASEAQPPVARTQPSS-----GVDSAVGT 1106
T ++ +S L + V L + PV R SS V +++
Sbjct: 3726 TTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSM 3785
Query: 1107 LPATSPQSTSVQAKGTNKLRKPKLPE----VQQATKAPESSDDSEDSSDSSSGSEEDGEG 1162
A+ S+ +GT + E + +P S ++S S+
Sbjct: 3786 TTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLST-------- 3837
Query: 1163 PQGAKSAHTLGPTPSRTETLVEE--TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1220
P G S L T + + ++ E T S + P +LL P P S AS
Sbjct: 3838 PPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIAS- 3896
Query: 1221 ATPKLDSSPSVSSTLAAKDDP 1241
TP LD+S + + + P
Sbjct: 3897 -TPPLDTSTTFTPSTDTASTP 3916
Score = 92.4 bits (228), Expect = 3e-18
Identities = 244/1278 (19%), Positives = 435/1278 (34%), Gaps = 124/1278 (9%)
Query: 65 AEEDAALQAKKTRVSDPISTS-ESSEEEEEAEAETAK-ATPRLASTN-SSVLGADLPSSM 121
+ E + L S P++TS E S AE + +TP ST +S+L + +P +
Sbjct: 2883 SSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAG 2942
Query: 122 KEKAKAETEKAGK------TGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
E + T + + P T + + +S R++ S + + +
Sbjct: 2943 SEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASS 3002
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSD---ETDVEGKPSVKPAQVKASSVSTKE 232
E S + A V+ SSS T+ + T EG + V + V+ E
Sbjct: 3003 EASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPE 3062
Query: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292
+ P VT + PA+ P + EGS P T
Sbjct: 3063 ASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMP---ISTYSEGSTPLTGVPVSTTPVTS 3119
Query: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSES----------- 341
++ L TP +T A + + P E S
Sbjct: 3120 SAISTLSTTPVDT---STPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLV 3176
Query: 342 -SSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAK 400
SSE+S+ S + + + + ++ S P +P +G P T V+
Sbjct: 3177 VSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTS-TPSEGMTPL----TSVPVSN 3231
Query: 401 AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP--APPRK 458
E S S+ DS + S P S P +P +G+ P + P
Sbjct: 3232 TPVASSEA-SILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTS-TPSEGSTPLTSMPVS 3289
Query: 459 TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 518
T A+ E S S+ +D+ A+ P+ + P ST G
Sbjct: 3290 TTTVASS-------ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM-PTSTYSEG--- 3338
Query: 519 KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578
+TP + SS + ++ + T V + E SL A
Sbjct: 3339 -------------STPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTT-A 3384
Query: 579 KPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKI 638
+ TS P P + P+A + P+ +SE + S+ DS T A + P I
Sbjct: 3385 EGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPT--I 3442
Query: 639 PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE 698
+ + P T + S ++ + + T A+S A + T P SS +
Sbjct: 3443 AEGTSLPTSTTSEGSTPLSIMPLSTTP-----VASSEASTLSTTPVDTSTPVTTSSPTNS 3497
Query: 699 SDSEEEKTGLAV-TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE 757
S + E T + T G+ + + V V + T PV + +Q +
Sbjct: 3498 SPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSS 3557
Query: 758 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 817
++ S E ++S T++ + + A PS + + +
Sbjct: 3558 PATLQVTTMRMSTPSEGSSS----LTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQS 3613
Query: 818 QAKQRSPSKVKPPVRNPQN-STVLARGPASVPSVGKAVATAAQAQTGPEEDS-----GSS 871
+ P + P+ P ST L P S SV ++ A A T P + S +
Sbjct: 3614 NSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSV--TISEAGTASTLPVDTSTPVITSTQ 3671
Query: 872 EEESDSEEEAETLAQVKPS-GKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD 930
S E T+ PS G T ++ + + +G+ + P + +
Sbjct: 3672 VSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEA 3731
Query: 931 DSGSSSEESDSDG-----EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQA-----QA 980
S S++ +S + E T+ V P+ + +P+ P+ + + +
Sbjct: 3732 ISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEG 3791
Query: 981 ASTPRKARASESTARSSSSESED---EDVIPATQCLTPGIRTNVVTMP--TAHPRI-APK 1034
+S+P + + S++SE +I ++P + + T P T+ P + + K
Sbjct: 3792 SSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTK 3851
Query: 1035 ASMAGASSSKESSRISDGKKQEGPATQ--VSKKNPASLPLTQAALKVLAQKASEAQPPV- 1091
A + + RIS ++ P T VS P S P A + PP+
Sbjct: 3852 AGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIA----------STPPLD 3901
Query: 1092 -ARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1150
+ T S ++ T+P + S SV +G+ +P + + + +
Sbjct: 3902 TSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAV 3961
Query: 1151 DSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG 1210
+ + + P + S+ T + ++ T T A ++ + S TP
Sbjct: 3962 STPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS------TPR 4015
Query: 1211 LTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTT 1270
T S +T S+P S+++ + + ++P P T A S T
Sbjct: 4016 TTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPT-FPPAHSSTP 4074
Query: 1271 PQKSRKPKKGAGNPQAST 1288
P S NP+A T
Sbjct: 4075 PTTS--ASSTTVNPEAVT 4090
Score = 57.4 bits (137), Expect = 1e-07
Identities = 106/511 (20%), Positives = 181/511 (35%), Gaps = 103/511 (20%)
Query: 833 NPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGK 892
NP+ +++ + + P V T +++T E S S+ S E +T + P G
Sbjct: 88 NPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTE--DTSSPTTPEGT 145
Query: 893 THQIRAALAPAKESPRK-----GAAPTP----------------PGKTGPSAAQAGKQDD 931
+ P++ES AP P P T A+ + +
Sbjct: 146 DVPMS---TPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPE 202
Query: 932 SGSSSEESDSDGEAPAA------------------VTSAQVIKPPLIFVDPNRSPA---G 970
S + + ++S+G P T ++ P I + SP G
Sbjct: 203 STTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEG 262
Query: 971 PAATPAQAQAASTPRKAR--------ASESTARSSSSESEDEDVIPATQCLTPGIRTNVV 1022
P+ + + STP +SE++ S++ + + VI +T+ +
Sbjct: 263 PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGT 322
Query: 1023 TMPT------AHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAA 1076
++PT + P + AS ++S E S +S S + P+SLP T A
Sbjct: 323 SIPTSTYTEGSTPLTSTPASTMPVATS-EMSTLSITPVDTSTLVTTSTE-PSSLPTTAEA 380
Query: 1077 LKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA 1136
+L SE P+ +P ++ S +A T+ + V A
Sbjct: 381 TSMLTSTLSEGSTPLT-------------NMPVSTILVASSEASTTSTIPVDSKTFVTTA 427
Query: 1137 TKAPESSDDSEDSSDSSSGSEED---------GEGPQGAKSAHTLGPTPSRTETLVEETA 1187
++A S +ED+S ++S E P + A L TP ++T V T+
Sbjct: 428 SEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQV-TTS 486
Query: 1188 AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1247
E+S A S+ + + G TP S + P S S ST
Sbjct: 487 TEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTS------- 539
Query: 1248 KPQQAAGMLSPKTGGKEA-ASGTTPQKSRKP 1277
+P T EA +S TTP+ + P
Sbjct: 540 ---------TPVTTSSEASSSSTTPEGTSIP 561
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 122 bits (305), Expect = 3e-27
Identities = 308/1587 (19%), Positives = 562/1587 (35%), Gaps = 233/1587 (14%)
Query: 72 QAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
Q KK + D SESS E + + K R S + S + K K K++ +K
Sbjct: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR--SESESKKRKHRSPTPKSKRKSKDKK 244
Query: 132 AGKTGNSMPHP--------ATGKTVANLLSGKSPRKSAEPSANTTLV--------SETEE 175
++ ++ P P + + ++ + +S +SA +TT + S
Sbjct: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSD-----ETDVEGKPSVKPAQVKASSVST 230
EG P ++PG S + S T S + D + K + +P+ S +
Sbjct: 305 EGDAP----FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
Query: 231 KESPARKAAPAPGKVGD-----VTPQVKGGALPPAK----RAKKPEEESESSEEGSESEE 281
E PA A G TP + PP++ R + P + E + S SE
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
Query: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGK-GATPAPPGKAGAVA------SQTKAGK 334
P+ ++V APA G+ + ++P ++ A S T + +
Sbjct: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480
Query: 335 PEEDSESSSEESSDSEEETPAAKALLQAKA-----SGKTSQVGAASAPAKESPRKGAAPA 389
++ + S TP + ++++ S + G + +P + + +P
Sbjct: 481 MGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRG--RSRSPQ 538
Query: 390 PPG----------------KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKA 433
PG + G + +++ A + S++ + S PA+ + +
Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
Query: 434 PQVRAASA--PAKESPRKGAAPA------------------PPRKTGPAAAQVQVGKQEE 473
P R + + PA+ + PA P R++G + ++ +
Sbjct: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRS 658
Query: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
SR+ + S R A + + + + + + S + V G+ T
Sbjct: 659 RSRTPARRGRS-RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-AKGPPQKA 592
P + S S + S +S + +P +KS + +++ SSP +K + +
Sbjct: 718 PQR---RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774
Query: 593 GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP---QTKACPKKTN 649
++ + P S++ S S S+ + T + + P Q P + +
Sbjct: 775 LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
Query: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 709
++S+ V+ GT P + G+ TSP + +V +R +SS E S
Sbjct: 835 HSSSSPHPKVKSGT--PPRQGSITSPQANEQSVT-PQRRSCFESSPDPELKSR------- 884
Query: 710 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP-------VLP------GKTGPTVTQVKA 756
T + G +S P + S + ++P + P G + P+ ++V +
Sbjct: 885 -TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTS 943
Query: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
S + E+ P + K P S G+IS KV
Sbjct: 944 RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT 1003
Query: 817 AQAKQRSPSKVKPPVRNPQNSTV--------LARGPASVPSVGK------AVATAAQAQT 862
S SK P ++S V L G S G+ ++ Q+QT
Sbjct: 1004 PPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQT 1063
Query: 863 GPEEDSG-SSEEESDSEEEAETL---AQVKP-SGKTHQIRAALAPAKESP----RKGAAP 913
P+ S SS E S E+ +L +Q P G++ A SP R +
Sbjct: 1064 SPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA 1123
Query: 914 TPPGKTGPSAAQAGKQDDSGS----SSEESDSDGEAPAAVTSAQVIKPP----------- 958
+P K+G S Q+ Q DS S S A + ++ PP
Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183
Query: 959 ----------------LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESE 1002
L+F D R+P P + A + + + S +SS + E
Sbjct: 1184 KDKFSPFPVQDRPESSLVFKDTLRTP------PRERSGAGSSPETKEQNSALPTSSQDEE 1237
Query: 1003 DEDVI-----PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS--SKESSRISDGKKQ 1055
+V+ PA Q L+ + + + M T++ +P+ A S +S + +
Sbjct: 1238 LMEVVEKSEEPAGQILS-HLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAV 1296
Query: 1056 EGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQST 1115
E P+ S P P + ++ S P R G + G +S
Sbjct: 1297 EVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTG---FSSEVKE 1353
Query: 1116 SVQAKGTNKLR-KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGP 1174
+ N+L P L +Q+T+ S S S E+ G + S+ L
Sbjct: 1354 DLNGPFLNQLETDPSLDMKEQSTR----SSGHSSSELSPDAVEKAGMSSNQSISSPVLDA 1409
Query: 1175 TPSRTETLVEETAAESSE--DDVV-APSQSLLSGYMTPGL-----TPANSQASKATPKLD 1226
P RT + ++A S E D + PS+ SG +PGL TP+ S ++P +
Sbjct: 1410 VP-RTPSRERSSSASSPEMKDGLPRTPSRRSRSG-SSPGLRDGSGTPSRHSLSGSSPGMK 1467
Query: 1227 SSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQA 1286
P S ++ D + +A PQ +P+ + +S K P++ ++
Sbjct: 1468 DIPRTPSRGRSECDSSPEPKALPQ------TPRPRSRSPSSPELNNKCLTPQRERSGSES 1521
Query: 1287 STLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRK 1346
S Q + + LGQ + + V QER + + ++ R+
Sbjct: 1522 S--VDQKTVARTPLGQ----RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQ 1575
Query: 1347 RKLSGDQP--------------AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKR 1392
R SG P + +P K K + + SPE + + +R
Sbjct: 1576 RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRR 1635
Query: 1393 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1452
+ SG + +G GS + PE + T G +S+P+ K + + +R+ +
Sbjct: 1636 SR-SGSSSKGRGPSPEGSSSTESSPEHPPKS--RTARRGSRSSPEPKTKSRTPPRRRSSR 1692
Query: 1453 EKKEKKKKAKKASTKDSESPSQKKKKK 1479
E +KA+ + S S S + + +
Sbjct: 1693 SSPELTRKARLSRRSRSASSSPETRSR 1719
Score = 115 bits (288), Expect = 3e-25
Identities = 288/1530 (18%), Positives = 550/1530 (35%), Gaps = 199/1530 (13%)
Query: 72 QAKKTRVSDPISTSE-----SSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
+A TR P + E SS E + K + +S+ S A P S +E +
Sbjct: 396 EASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISS 455
Query: 127 AETEK--------AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE--- 175
+ T K K+ + P G++ + + + +S P+ S + +
Sbjct: 456 SPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRR 515
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP-SVKPAQVKASSVSTKESP 234
S +G + P G++ S S S T G+ S + + + S +T+
Sbjct: 516 SRSAQRWGRSRSPQR--RGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573
Query: 235 ARKAAPAPGKVGDVTP-QVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
+ G+ TP + + + P +R + + S + + TRS V+
Sbjct: 574 RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRR 633
Query: 294 SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET 353
R+ S + + TPA G++ S+T A + S + + S S T
Sbjct: 634 RS-----RSRSPARRSGRSRSRTPARRGRS---RSRTPARRGRSRSRTPARRSGRSRSRT 685
Query: 354 PAAKALLQAKA-----SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE 408
PA + +++ S S V + ++ R+G + G + K++ +R
Sbjct: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS----GSSSERKNKSRTSQRRS 741
Query: 409 DSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 468
S SS E S ++ S +P+ +A S + G++P P +K+ Q
Sbjct: 742 RSNSSPEMKKSR--ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKS-------QT 792
Query: 469 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 528
+ S SS ++ S + +++ P KS S P K PP +
Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852
Query: 529 VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 588
+P A S E S D + P++ G+ +S+P +
Sbjct: 853 GSITSPQANEQSVTPQRRSCFESSPDPE----LKSRTPSRHSCSGSSPPRVKSSTPPRQS 908
Query: 589 PQKAGPVAVQVKAE-KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
P ++ +VKA P S S S + + P + +++ P+
Sbjct: 909 PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV-ESRLLPRY 967
Query: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGS-SPAVAGGTQRPAEDSSSSEESDSEEEKT 706
+++ +S+ V+ T PR+ S +GS SP Q P S S +S +EK+
Sbjct: 968 SHSGSSSPDTKVKPETP-PRQ-----SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKS 1021
Query: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
++ S+ VK+++ P + G + L G++ Q + + D+ S E
Sbjct: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQ-LKGQS-----QTSPDHRSDTSSPE 1075
Query: 767 EESDSEEAAASPAQVKTSVK----KTQAKANPAAARAP--SAKGTISAPGKVVTAAA--Q 818
E+ + ++ +TS K ++ + A+R+P +G SA + + + Q
Sbjct: 1076 VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQ 1135
Query: 819 AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSE 878
++ +S S P V ++++L + + +A P+ED+ +S +
Sbjct: 1136 SRFQSDSSSYPTV---DSNSLLGQSRLETAESKEKMALP------PQEDATASPPRQ-KD 1185
Query: 879 EEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDD------- 931
+ + Q +P P +E R GA +P K SA QD+
Sbjct: 1186 KFSPFPVQDRPESSLVFKDTLRTPPRE--RSGAGSSPETKEQNSALPTSSQDEELMEVVE 1243
Query: 932 -------------SGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQA 978
S E S S+ E+ V + + +D ++S A A +
Sbjct: 1244 KSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVS---LTLDQSQSQASLEAVEVPS 1300
Query: 979 QAAS------TPRKARASESTARSSS--SESEDEDVIPATQCLTPGIRTNV--------V 1022
A+S +P S S R +S S E + P + G + V +
Sbjct: 1301 MASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFL 1360
Query: 1023 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPA--SLPLTQAALKVL 1080
P + K +S S D ++ G ++ S +P ++P T + +
Sbjct: 1361 NQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSS 1420
Query: 1081 AQKASEAQPPVARTQP-------SSGVDSAVGT---------------LPAT-------- 1110
+ + E + + RT S G+ GT +P T
Sbjct: 1421 SASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSEC 1480
Query: 1111 --SPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1168
SP+ ++ + R P PE+ P+ S+SS + P G +S
Sbjct: 1481 DSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRE---RSGSESSVDQKTVARTPLGQRS 1537
Query: 1169 ----AHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPK 1224
+ L PS + +E + S D A +++ L G +P S+ +P+
Sbjct: 1538 RSGSSQELDVKPSASP---QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594
Query: 1225 LD---SSPSVS----STLAAKDDPDGKQEAK-PQQAAGMLSPKTGGKEAASGTTPQKSRK 1276
SSP V + A+ D E K P A ++G G +P+ S
Sbjct: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
Query: 1277 PKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE 1336
+ +P S A + + + P P +++ R++ ++ E
Sbjct: 1655 TESSPEHPPKSRTARRGSRSS-----PEPKTKSRTPP-------------RRRSSRSSPE 1696
Query: 1337 SSRKGWESRKRKLSGDQPAART---PRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRD 1393
+RK SR+ + + P R+ PR ++ + + E E S S + + S + K
Sbjct: 1697 LTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756
Query: 1394 KASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE 1453
G K +G S+ E+ + G + ++++ +S R +
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSR--SRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRR 1814
Query: 1454 KKEKKKKAKKASTKDSESPSQKKKKKKKKT 1483
+ ++ + ++S S ++++ + +T
Sbjct: 1815 RGGSGYHSRSPARQESSRTSSRRRRGRSRT 1844
Score = 108 bits (269), Expect = 5e-23
Identities = 246/1329 (18%), Positives = 451/1329 (33%), Gaps = 188/1329 (14%)
Query: 243 GKVGDVTPQVKG--GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV------KAS 294
G+ TPQ +G G+ K + + S E ++ + RS+ KA
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
++ R+ S + K TP ++G+ + K+ P S SSS + +TP
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
Query: 355 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSS 414
S+ +S+ + G P T P + + SS
Sbjct: 831 --------------SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
Query: 415 EESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED 474
+ + + P++ SG +P +S P ++SP + ++P P K + +Q
Sbjct: 877 PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKA------IISPRQRSH 930
Query: 475 SRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 534
S SSS + V P + + P KV P TP
Sbjct: 931 SGSSSPSPSRVTSRTTPRRSRSVSPCSN------VESRLLPRYSHSGSSSPDTKVKPETP 984
Query: 535 SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA-------QEKSLGNILQAKPTSSPAKG 587
Q S S S + P + + QEKS +++Q+ P S
Sbjct: 985 PRQ-------SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCA 1037
Query: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
+ + P + S+ S D +P + P+L+ +++ PK
Sbjct: 1038 GVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQ-SKSQTSPKG 1096
Query: 648 TNTTASAKVAPVRVGTQAPRKAGT-ATSP---AGSSPA----VAGGTQRPAEDSSS---S 696
+ +S+ V + + + G + SP +G SP + + P DS+S
Sbjct: 1097 GRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQ 1156
Query: 697 EESDSEEEKTGLAV------TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLP------ 744
++ E K +A+ T + K P + + T P
Sbjct: 1157 SRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGA 1216
Query: 745 GKTGPTVTQVKA--EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN----PAAAR 798
G + T Q A +D E E SEE A +S K + +N P
Sbjct: 1217 GSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEE 1276
Query: 799 APSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
P+ T+ + A S P +P++ L+ P S G +
Sbjct: 1277 RPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKE-LSNSPLRENSFGSPLEFRN 1335
Query: 859 QAQTGPEEDSG-SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 917
G E ++G SSE + D + PS L ++S R
Sbjct: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPS---------LDMKEQSTR--------- 1377
Query: 918 KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
SG SS E D A ++S Q I P++ P R+P+ ++ A
Sbjct: 1378 -------------SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVP-RTPSRERSSSAS 1423
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPATQCL---TPGIRTNVVT----------- 1023
+ S + SS D P+ L +PG++ T
Sbjct: 1424 SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS 1483
Query: 1024 -MPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ 1082
P A P+ S + +S + ++ +++ G + V +K A PL Q + +Q
Sbjct: 1484 PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ 1543
Query: 1083 K--ASEAQPPVARTQPSSGVDSAVGT--------LPATSPQSTSVQAKGTNKLRKPKLPE 1132
+ + P R++ S DS T +SP+ S + R PE
Sbjct: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603
Query: 1133 VQQATKAPESSDDSEDSSD-------------SSSGSEEDGEG--PQGAKSAHTLGPTPS 1177
V+ +A + DSS S SGS G G P+G+ S + P
Sbjct: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
Query: 1178 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVS-STLA 1236
++ T + SS + T TP ++S+++P+L +S + +
Sbjct: 1664 KSRT--ARRGSRSSPEP------------KTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
Query: 1237 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1296
A P+ + P+ SP E A +S + ++ A +P+ T + +
Sbjct: 1710 ASSSPETRSRTPPRHRR---SPSVSSPEPAE---KSRSSRRRRSASSPRTKTTSRRGRSP 1763
Query: 1297 QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESR--KRKLSGDQP 1354
+P L ++ ++ K T T++ R SR +R+ G
Sbjct: 1764 S---PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY 1820
Query: 1355 AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK 1414
+R+P ++ + + S +T TS+ +++ + K + + S +
Sbjct: 1821 HSRSPARQESSRTSSRRRRGRS----RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRS 1876
Query: 1415 DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1474
+ + S +S+ + +R + + +++++ S +P
Sbjct: 1877 RSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR------SRTPPV 1930
Query: 1475 KKKKKKKKT 1483
+++ + +T
Sbjct: 1931 TRRRSRSRT 1939
Score = 107 bits (267), Expect = 9e-23
Identities = 261/1322 (19%), Positives = 483/1322 (36%), Gaps = 160/1322 (12%)
Query: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
A++ AP P K + + P K+ KK +++ + G SE +P R + K S
Sbjct: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKK----DRGRRSESSSP---RRERKKS 212
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAV-------ASQTKAGKPEEDSESSSEESS 347
K + R+ S K K +P P K + S T A K S+S +S+
Sbjct: 213 SKKKKHRSESESKKR---KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
Query: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
S + T +++ A + T+ G + +PA S R+G AP ++ G
Sbjct: 270 SSSD-TSRSRSRSAAAKTHTTALAGRSPSPA--SGRRGEGDAP---------FSEPGTTS 317
Query: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
SS E + + +P + K K + ++A+ P+ R P PP T P A+
Sbjct: 318 TQRPSSPETATKQPSSPYEDKDKDK--KEKSATRPSPSPERSSTGPEPPAPT-PLLAERH 374
Query: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP-P 526
G + + + + + + A+ + P KSP+ P S+ + + P P P
Sbjct: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPP--KSPEKLPQSSS-----SESSPPSPQP 427
Query: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-SPA 585
KV S+ + S E S S PT ++ +S G + K S +P+
Sbjct: 428 TKVSRHASSSPESPKPAPAPGSHREISSS-----PT----SKNRSHGRAKRDKSHSHTPS 478
Query: 586 KGPPQKAGPVAV---QVKAEKPMDNSESSEESSDSADSEEAP--AAMTAAQAKPALKIPQ 640
+ + P + ++ P S S S A + Q + + PQ
Sbjct: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
Query: 641 TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG--GTQRPAEDSSSSEE 698
+ NT + R G R T +PA G ++ PA S S
Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV---------LPGKTGP 749
++ G+++S + PV+ + +P P + G
Sbjct: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR-RRSRSRSPARRSGRSRSRTPARRGR 657
Query: 750 TVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA----------ARA 799
+ ++ A + + + +PA+ S +T + + +R
Sbjct: 658 SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS---------- 849
P +G + + + +++RS S P ++ + S+ +R +S S
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 850 --VGKAVATAAQAQTGPEED-SGSSEEESDSE---EEAETLAQVKPSGKTHQIRAALAPA 903
G + ++QT P SGSS+ ++ S + + + P K+ +
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
Query: 904 KESPRKGAAPTPPGKTGPSAAQAGKQD--DSGSSSEESDSDGEAPAAVTSAQVI---KPP 958
K + TPP + ++ QA +Q S ES D E + S PP
Sbjct: 838 SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897
Query: 959 LI--FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 1016
+ P +SP+ ++ + +A +PR+ S S++ S S T TP
Sbjct: 898 RVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSR---------VTSRTTPR 948
Query: 1017 IRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE-----GPATQVSKKNPASLP 1071
+V R+ P+ S +G+SS + +Q P +V + P
Sbjct: 949 RSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPS 1008
Query: 1072 LTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQS-----TSVQAKGTNKLR 1126
L+ + +K+ ++ + ++ P S + G +T P +S+Q KG ++
Sbjct: 1009 LSGSKSPCPQEKSKDS---LVQSCPGS-LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS 1064
Query: 1127 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEET 1186
P+ + T +PE +S S S+ P+G +S + T + + + +
Sbjct: 1065 ----PDHRSDTSSPEVRQSHSESPSLQSKSQ---TSPKGGRSRSSSPVTELASRSPIRQD 1117
Query: 1187 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1246
E S + +L M+P + S +S + P +DS+ + + + K
Sbjct: 1118 RGEFS-------ASPMLKSGMSPEQSRFQSDSS-SYPTVDSNSLLGQSRLETAESKEKMA 1169
Query: 1247 AKPQQAAGMLSPKTGGKEAASGT--TPQKS-------RKPKKGAGNPQASTLALQSNITQ 1297
PQ+ A P+ K + P+ S R P + +S + N
Sbjct: 1170 LPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSAL 1229
Query: 1298 CLLGQPWPLNEA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPA 1355
Q L E + + ++L+ L E K++ + ESS + E L+ DQ
Sbjct: 1230 PTSSQDEELMEVVEKSEEPAGQILSH-LSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ 1288
Query: 1356 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---G 1412
++ + A G SPE ++ R+ + G E + G LG++ G
Sbjct: 1289 SQASLEAVEVPSMASSWGGPHFSPEHKELSN--SPLRENSFGSPLEFRNSGPLGTEMNTG 1346
Query: 1413 AKDEPEEELQKGMGTVEGGDQSNPK--SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSE 1470
E +E+L G +++P K++ +S + + +KA +S +
Sbjct: 1347 FSSEVKEDLN---GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSIS 1403
Query: 1471 SP 1472
SP
Sbjct: 1404 SP 1405
Score = 103 bits (258), Expect = 9e-22
Identities = 281/1505 (18%), Positives = 515/1505 (34%), Gaps = 217/1505 (14%)
Query: 82 ISTSESSEEEEEAEA---ETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGN- 137
++T SSE +E+ + P L S + SS E + EKAG + N
Sbjct: 1343 MNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS--ELSPDAVEKAGMSSNQ 1400
Query: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
S+ P ++P + SA++ + + + + PG+
Sbjct: 1401 SISSPVLDAVP------RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
Query: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGAL 257
S + SS D+ PS + ++ S+ E A P P +P++ L
Sbjct: 1455 SRHSLSGSSPGMKDIPRTPS----RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCL 1510
Query: 258 PPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
P + E S ++ P G RS+ +S++ L V+ +++P + + +
Sbjct: 1511 TPQR-----ERSGSESSVDQKTVARTPLGQRSRSGSSQE-LDVKPSASPQERSESDSSPD 1564
Query: 318 APPGKAGAVASQTKAGK-PEEDSESS----SEESSDSEEETPAAKALLQAKASGKTSQVG 372
+ + ++++G PE DS+S S S E +A +A++ +S
Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
Query: 373 AASAPA-------KESPRKGAAPAPPGKTG--------PAVAKAQAGKREEDSQSSSEES 417
A AP S KG P+P G + P A+ G R SS E
Sbjct: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR------SSPEP 1678
Query: 418 DSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS 477
++ P + + S +P++ + ++ S ++P +T P + S S
Sbjct: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR-------HRRSPSVS 1731
Query: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
S E ++ R + +A+ SP+ K S G P P P G + S +
Sbjct: 1732 SPEPAEKSRSSRRRRSAS-------SPRTKTTSRRGRSP-----SPKPRGLQRSRSRSRR 1779
Query: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKP------TSSPAKGPPQK 591
++ + D S T+ + +S + + + + SPA+ +
Sbjct: 1780 -------EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR 1832
Query: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT 651
+ ++ P + + S + A P + ++A PA P +
Sbjct: 1833 TSSRRRRGRSRTPPTSRKRSRSRTSPA-----PWKRSRSRASPATHRRSRSRTPLISRRR 1887
Query: 652 ASAKVAPV-----RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
+ ++ +PV R T R+ + + S T S S +
Sbjct: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947
Query: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
V + +S ++ + PV + + + + T ++ S +S
Sbjct: 1948 SRTPPVTRRRS-------RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
Query: 767 EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSK 826
+ SP + S +T P A R S T P K +++ RSP
Sbjct: 2001 VTRRRSRSRTSPVTRRRSRSRT-----PPAIRRRSRSRTPLLPRK------RSRSRSPLA 2049
Query: 827 VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
++ R+ T ARG S+ A+ + SGSS + S S T +
Sbjct: 2050 IRRRSRSRTPRT--ARGKRSLTRSPPAIRRRSA--------SGSSSDRSRSATPPAT--R 2097
Query: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTP------PGKTGPSAA---------QAGKQ-- 929
+T + + R +PTP PG P + QAG
Sbjct: 2098 NHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMM 2157
Query: 930 --------DDSGSSSEESDSDGEAPAAVTSAQV--IKPPLIFVDPNRSPAGPAATPAQAQ 979
D +S E+ + A+T+ + +PP P+ S AG AA +Q
Sbjct: 2158 DGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP-----PSMSAAGLAARMSQVP 2212
Query: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
A R + + +S + + TP I T V + P A ++A
Sbjct: 2213 APVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLAS 2272
Query: 1040 ASSSKESSRIS--DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1097
++ S ++ D + PA ++ T AAL L+ S P A S
Sbjct: 2273 PRTAVAPSAVNLADPRTPTAPAVNLAGAR------TPAALAALSLTGSGTPPTAANYPSS 2326
Query: 1098 SGVDSAVGTLPATSPQSTSVQAK----GTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS 1153
S A + P+S A G+ + A AP S + S
Sbjct: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
Query: 1154 SGSEEDGEG----PQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTP 1209
+ E G P ++ P+ + E A S APSQSLL
Sbjct: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQ 2446
Query: 1210 GLTPANSQAS--------KATPKLDS----SPSVSSTLAAKDDPDGKQEAK----PQQAA 1253
+P S S + TP S S +V++T ++ D +G P
Sbjct: 2447 PRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDV 2506
Query: 1254 GMLSPKTGGKE--AASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQV 1311
G TG ++ A + P K R+ + + +S+ + S+ + + +
Sbjct: 2507 GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS---SSSDS 2563
Query: 1312 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1371
+ S + V E+ + KE+ R+G +P TP +K++ +
Sbjct: 2564 EGSSLPVQPEVALKRVPSPTPAPKEAVREG-----------RPPEPTPAKRKRRSSSSSS 2612
Query: 1372 GGEASVSPEKTSTTSKGKAKRDKASGDVKE----------KKGKGSLGSQGAKDEPEEEL 1421
+S S +S++S + +S K G +L + +P
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE 2672
Query: 1422 QKGMGTVEGGDQSNPKSKKEKKKSDKRK-------KDKEKKEKKKKAKKASTKDSESPSQ 1474
++ + D ++R+ +D++ ++ +++ DS SPS
Sbjct: 2673 RRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSH 2732
Query: 1475 KKKKK 1479
K++++
Sbjct: 2733 KRRRE 2737
Score = 102 bits (253), Expect = 4e-21
Identities = 276/1514 (18%), Positives = 523/1514 (34%), Gaps = 204/1514 (13%)
Query: 95 EAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSG 154
E A ++P NS++ + + E + E AG+ + + + +N S
Sbjct: 1212 ERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES- 1270
Query: 155 KSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEG 214
SP P+ + TL ++ S + A P M S+ S + S+ E
Sbjct: 1271 -SPEVEERPAVSLTL----DQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLREN 1325
Query: 215 KPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSE 274
S + + S G +V + G L + + + +S+
Sbjct: 1326 S--------FGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTR 1377
Query: 275 E-GSESEEEAP-----AGTRSQVKASEKILQV------RAASAPAKGTPGKGATPAPPGK 322
G S E +P AG S S +L R S+ A K P P +
Sbjct: 1378 SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSR 1437
Query: 323 AGAVAS----QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPA 378
S + +G P S S S TP+ + + +S + + P
Sbjct: 1438 RSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS-RGRSECDSSPEPKALPQTPRPR 1496
Query: 379 KESP---------------RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 423
SP R G+ + KT VA+ G+R SS+E D + A
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQKT---VARTPLGQRSRSG--SSQELDVKPSA 1551
Query: 424 -PAQAKPSGKAPQVRAAS-APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE 481
P + S +P +A + P ++ R G++P K+ ++ + S SS E
Sbjct: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS-------RLSPRRSRSGSSPEV 1604
Query: 482 SDSDREALAAMNAAQVKPLGKSPQVKPASTMGM-GPLGKGAGPVPPGKVGPATPSAQVGK 540
D R A A + + P K+P + G KG GP P G
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG------------- 1651
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
SSS ESS + TA G+ +P + P +++ + ++
Sbjct: 1652 ------SSSTESSPEHPPKSRTA-------RRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698
Query: 601 AEKPMDNSESSEESSDSADSEEAPA---AMTAAQAKPALKIPQTKACPKKTNTTASAKVA 657
+ + S SS S P + + + +PA K ++ +++ ++ K
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR--RRSASSPRTKTT 1756
Query: 658 PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKS 717
R + +P+ G S + S T+R + S SS+ + +++ V + +
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRR-RDRSGSSQSTSRRRQRSRSRSRVTRRRR 1815
Query: 718 VGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAAS 777
G G ++ P + + ++ G++ T K + S + + S S + A+
Sbjct: 1816 GGSGYHSRS---PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPAT 1872
Query: 778 PAQVKT-----SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVR 832
+ ++ S ++++++ +P + R ++ +++ A+ +++RS S+ P R
Sbjct: 1873 HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
Query: 833 NPQNS---TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD-----SEEEAETL 884
S T R + P V + ++++T P S S S +
Sbjct: 1933 RRSRSRTPTTRRRSRSRTPPVTRR---RSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPV 1989
Query: 885 AQVKPSGKTHQIRAALAPAKESP---RKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES-- 939
+ + +T + + ++ SP R+ + TPP S ++ S S
Sbjct: 1990 TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLA 2049
Query: 940 ---DSDGEAPAAVTSAQVI--KPPLI---FVDPNRSPAGPAATPAQAQAASTPRKARASE 991
S P + + PP I + S +ATP + S R +
Sbjct: 2050 IRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2109
Query: 992 STARSSSSESEDEDVIPATQCLTPGI---------------------------------R 1018
+++R S P +C +PG+ R
Sbjct: 2110 NSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQR 2169
Query: 1019 TNV---------------VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVS 1063
T+V +++ TA P + A+ A S+ + + + PA ++
Sbjct: 2170 TSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLA 2229
Query: 1064 KKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTN 1123
+ PA+ AA LA + A P A S +A + SP+ T+V N
Sbjct: 2230 SRIPAA----SAAAMNLASARTPAIP-TAVNLADSRTPAAAAAMNLASPR-TAVAPSAVN 2283
Query: 1124 KL--RKPKLPEVQQA-TKAPES----SDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTP 1176
R P P V A + P + S + +++ PQ SA+ +GP
Sbjct: 2284 LADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRS 2343
Query: 1177 SRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLA 1236
+ V + ++ +AP+ SL S M P L+ AN + + S ++
Sbjct: 2344 AHATAPVNIAGSRTAA--ALAPA-SLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPP 2400
Query: 1237 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1296
D + + M S + + G P +S P P++ + S+ +
Sbjct: 2401 LLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP-AQDQPRSPVPSAFSDQS 2459
Query: 1297 QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG-DQPA 1355
+CL+ Q P+ +Q +S T + ++ +G QP+
Sbjct: 2460 RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPS 2519
Query: 1356 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK- 1414
A K++ + +S S +S++S + +S D S+G+
Sbjct: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD-----------SEGSSL 2568
Query: 1415 -DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1473
+PE L++ ++ + + + KRK+ + +S+ S S S
Sbjct: 2569 PVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628
Query: 1474 QKKKKKKKKTAEQT 1487
++ +
Sbjct: 2629 SSSSSSSSSSSSSS 2642
Score = 97.4 bits (241), Expect = 9e-20
Identities = 238/1250 (19%), Positives = 431/1250 (34%), Gaps = 179/1250 (14%)
Query: 98 TAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMPHPATGKTVANLLSGK 155
+ + PR+ S+ SS + K KA + +G+S P P+ + S
Sbjct: 892 SGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS------RVTSRT 945
Query: 156 SPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGK 215
+PR+S S + + S +P + + S S D + K
Sbjct: 946 TPRRSRSVSPCSNVESRL-----LPRY--------------------SHSGSSSPDTKVK 980
Query: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS-E 274
P P Q + S+S + P P G +P P+E+S+ S
Sbjct: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSP--------------CPQEKSKDSLV 1026
Query: 275 EGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGK 334
+ AG +S E V +S KG SQT
Sbjct: 1027 QSCPGSLSLCAGVKSSTPPGESYFGV--SSLQLKG-----------------QSQT---S 1064
Query: 335 PEEDSESSSEESSDSEEETPAAKALLQ-------AKASGKTSQVGAASAPAKESPRKGAA 387
P+ S++SS E S E+P+ ++ Q +++S +++ + S ++ A+
Sbjct: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
Query: 388 PAPPGKTGPAVAKAQAGKREEDS--------QSSSEESDSEEE--APAQAKPSGKAPQVR 437
P P ++ Q+ + QS E ++S+E+ P Q + P+ +
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK 1184
Query: 438 AASAPAKESPR-------KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
+P R K PPR+ A + + +Q S+ S D E +
Sbjct: 1185 DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ----NSALPTSSQDEELME 1240
Query: 491 AMNAAQVKPLGK-----SPQVKPASTMGMGPLGK-GAGPVPPGKVGPATPSAQVGKWEED 544
+ ++ +P G+ S ++K ST + P + + A + E
Sbjct: 1241 VVEKSE-EPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299
Query: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK---------PTSSPAKGPPQKAGPV 595
S +SS S + +P +E S G+ L+ + T ++ GP
Sbjct: 1300 SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
Query: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA--QAKPALKIPQTKACPKKTNTTAS 653
Q++ + +D E S SS + SE +P A+ A + ++ P A P+ + S
Sbjct: 1360 LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS 1419
Query: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
+ + + PR + S +GSSP + G+ P+ S S ++ +
Sbjct: 1420 SSASSPEMKDGLPR-TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD--------IP 1470
Query: 714 QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEE 773
+ S G+ + S P +L Q P + P + Q + SE D +
Sbjct: 1471 RTPSRGRS---ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527
Query: 774 AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN 833
A +P ++ +Q +A + S+P +QRS S P V +
Sbjct: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
Query: 834 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKT 893
+ S P V A +AQ+G SDS E + A P
Sbjct: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSG-----------SDSSPEPKAPA---PRALP 1633
Query: 894 HQIRAALAPAKESPRKGAAPTPPG----KTGPSAAQAGKQDDSGS-SSEESDSDGEAPAA 948
+ R+ S KG P+P G ++ P + GS SS E + P
Sbjct: 1634 RRSRSG------SSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR 1687
Query: 949 VTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIP 1008
S++ P + S +A+ + + TP + R S S SS E ++
Sbjct: 1688 RRSSR--SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV---SSPEPAEKSRSS 1742
Query: 1009 ATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS-SSKESSRISDGKKQEGPATQVSKKNP 1067
+ RT + P P+ S S +E +R + + + G + S++
Sbjct: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ 1802
Query: 1068 ASLPLTQAALKVLAQKASEAQPPV---------------ARTQPSSGVDSAVGTLPATSP 1112
S ++ + ++ P +RT P+S S T PA
Sbjct: 1803 RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWK 1862
Query: 1113 QSTSVQAKGTNKLRKPKLPEV----QQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1168
+S S + T++ + + P + ++ +P S S + + P +
Sbjct: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR 1922
Query: 1169 AHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSS 1228
+ + P +R + P S TP +T S++ + S
Sbjct: 1923 SRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRS 1982
Query: 1229 PSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1278
S +S + + +++ SP T + + S T P R+ +
Sbjct: 1983 RSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT-RRRSRSRTPPAIRRRSR 2031
Score = 94.0 bits (232), Expect = 1e-18
Identities = 260/1333 (19%), Positives = 466/1333 (34%), Gaps = 207/1333 (15%)
Query: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
S E +A +T + PR S +S L + +E++ +E+ KT P +
Sbjct: 1482 SSPEPKALPQTPR--PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR- 1538
Query: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSS- 206
SG S +PSA+ E E S P A + + ++ SS E S S
Sbjct: 1539 -----SGSSQELDVKPSASP---QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
Query: 207 --------SDETDVEGKPSVKP-AQVKASSVSTKESPARKAAPAPGKVGDVT----PQVK 253
+V+ KP P AQ + S ++PA +A P + G + P +
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 254 GGALPPAKRAKKPEEESESSEEGSESEEEAPA---------GTRSQVKASEKILQVRAAS 304
G + + P+ S ++ GS S E +RS + + K R +
Sbjct: 1651 GSSSTESSPEHPPK--SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSR 1708
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET----------- 353
+ + + TP ++ +V+S +P E S SS S S T
Sbjct: 1709 SASSSPETRSRTPPRHRRSPSVSSP----EPAEKSRSSRRRRSASSPRTKTTSRRGRSPS 1764
Query: 354 PAAKALLQAKASGKTSQV---------GAASAPAKESPR-KGAAPAPPGKTGPAVAKAQA 403
P + L ++++ + + G++ + ++ R + + + G + +++
Sbjct: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
Query: 404 GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
R+E S++SS P ++ K + R + AP K S R A+PA R++
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSR---KRSRSRTSPAPWKRS-RSRASPATHRRSRSRT 1880
Query: 464 AQVQVGKQEEDS------RSSSEESDSDREALA-AMNAAQVKPLGKSPQVKPASTMGMGP 516
+ + + RS S S + R + + A ++ + ++P V + P
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
Query: 517 LGKGAG-----PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS 571
+ PV + TP + + + S S V + ++
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
Query: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK-----PMDNSESSE-----ESSDSADSE 621
+ TS + + P A++ ++ P S S S S
Sbjct: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPR 2060
Query: 622 EAPAAMTAAQAKPALKIPQTK---------ACPKKTNTTASAKVAPVRVGTQ-------- 664
A + ++ PA++ A P T + ++ PV + +
Sbjct: 2061 TARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRP 2120
Query: 665 --APRKAGTATSP------------------AGSSPAVAGGTQRPAEDSSSSEESDSEEE 704
+P SP AG S G + P +S E+ ++
Sbjct: 2121 SMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS- 2179
Query: 705 KTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSES 764
+ LA+T + + AA + + S P++ +T P A + + +
Sbjct: 2180 RIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANL--ASRIPAASA 2237
Query: 765 SEEESDSEEAAASPAQVKTSVKKTQAKA------NPAAARAPSAKG-----TISAP---- 809
+ S A P V + +T A A +P A APSA T +AP
Sbjct: 2238 AAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNL 2297
Query: 810 -GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
G AA A + S P N +S+ + PAS VG A A T P +
Sbjct: 2298 AGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA----TAPVNIA 2353
Query: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP------GKTGPS 922
GS + + T A++ P+ + + P R +PP +T PS
Sbjct: 2354 GSRTAAALAPASL-TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS 2412
Query: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ--- 979
A + + S S G+AP+ Q + PP D RSP P+A Q++
Sbjct: 2413 APSQSRMTSERAPSPSSRM-GQAPS-----QSLLPPA--QDQPRSPV-PSAFSDQSRCLI 2463
Query: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
A +TP S S+ +++ S D PG+ + V P A +++A
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Query: 1040 ASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSG 1099
+KE S ++ S + +S +S+++ QP
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSS--------SSSGSSSSDSEGSSLPVQP--- 2572
Query: 1100 VDSAVGTLPATSPQSTSVQAKGTNKLRKP---KLPEVQQATKAPESSDDSEDSSDSSSGS 1156
+ A+ +P+ +P +G P K ++ + SS S SS SSS S
Sbjct: 2573 -EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631
Query: 1157 EEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1216
+ S+ + P+P++ P L +P P
Sbjct: 2632 SSSSSSSSSSSSSSSSSPSPAK-------------------PGPQALPKPASPKKPPPGE 2672
Query: 1217 QASKATPK----LDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQ 1272
+ S++ K L S S+S + + P + + QQ++ S + G + G +
Sbjct: 2673 RRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSS---SSERGSRRGQRGDSRS 2729
Query: 1273 KSRKPKKGAGNPQ 1285
S K ++ +P+
Sbjct: 2730 PSHKRRRETPSPR 2742
Score = 78.2 bits (191), Expect = 6e-14
Identities = 189/1033 (18%), Positives = 336/1033 (32%), Gaps = 77/1033 (7%)
Query: 60 GRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLA------STNSSVL 113
G +R + + TR D +S+S+ + ++ T R S + +
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ 1828
Query: 114 GADLPSSMKEKAKAETEKAG-KTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172
+ SS + + ++ T K S PA K + S + R+S + T L+S
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR---SRTPLISR 1885
Query: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKE 232
S + S S S S P V + ++ + +T+
Sbjct: 1886 RRSRSRTSPVSRRRSRSRTSVTRRRSRSR-ASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944
Query: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292
+ P VT + PP R + S + S S RS+ +
Sbjct: 1945 RSRSRTPP-------VTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSR 1997
Query: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES--SDSE 350
S + + R+ S + T + + PP S+T P + S S S + S
Sbjct: 1998 TSP-VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPL-LPRKRSRSRSPLAIRRRSR 2055
Query: 351 EETP-AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG---PAVAKAQAGKR 406
TP A+ S + +AS + + R PA +G P VA +
Sbjct: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
Query: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
S S +P +P G + + A S G P P
Sbjct: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP---------- 2165
Query: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
+ R+S E+ + A+ A + P + A + + PVP
Sbjct: 2166 ------DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR--MSQVPAPVPL 2217
Query: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS---LGNILQAKPTSS 583
+ A P+A + + +++ + + +PTAV A ++ + A P ++
Sbjct: 2218 MSLRTA-PAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTA 2276
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
A A P A + ++ S P TAA + + PQ A
Sbjct: 2277 VAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPP--TAANYPSSSRTPQAPA 2334
Query: 644 CPKKTNTTASAKVAPVRVGTQ--APRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDS 701
++ APV + A A + + A +PA++G S+ E S
Sbjct: 2335 SANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVS 2394
Query: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
L + + S P + + AP + G +Q +D
Sbjct: 2395 GRTSPPL---------LDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445
Query: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
S S + + T V +Q+ ++ A A S+ G + V
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505
Query: 822 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
+ P L S + ++++ + + S SS S S+ E
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
Query: 882 ETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
+L V+P ++ + KE+ R+G PTP + S++ + S SSS S
Sbjct: 2566 SSLP-VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 940 DSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSS 999
S + ++ +S+ P+ + GP A P A P R S S + S
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDS 2684
Query: 1000 ESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPA 1059
+ + + + P P +SSS+ SR P+
Sbjct: 2685 LRDSRSL-------------SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
Query: 1060 TQVSKKNPASLPL 1072
+ ++ P+ P+
Sbjct: 2732 HKRRRETPSPRPM 2744
Score = 71.6 bits (174), Expect = 5e-12
Identities = 121/513 (23%), Positives = 191/513 (37%), Gaps = 66/513 (12%)
Query: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRV-SDPISTSESSEEEEEAEAETAKA 101
PV L+ + T + L + A AA+ R + P + + + A A A
Sbjct: 2214 PVPLMSLRT--APAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271
Query: 102 TPRLASTNSSVLGAD--LPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRK 159
+PR A S+V AD P++ A S+ T T AN S +
Sbjct: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSS---R 2328
Query: 160 SAEPSANTTLVSETEEEGSVPA-------FGAAAKPGMVSAGQADSSSEDTSSS-----S 207
+ + A+ LV + P A A + SA A + S +S S
Sbjct: 2329 TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLS 2388
Query: 208 DETDVEGKPSVKPAQVKASSVSTKESPAR-----KAAPAPG-KVGDVTPQVKGGALPPAK 261
V G+ S P +A S + +P++ + AP+P ++G Q LPPA+
Sbjct: 2389 AYERVSGRTS-PPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ---SLLPPAQ 2444
Query: 262 ---RAKKPEEESESSE---------EGSES-EEEAPAGTRSQVKASEKILQVRAASAPAK 308
R+ P S+ S GS+S A A T S +L V A P
Sbjct: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
Query: 309 --GTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 366
G P P A+ + S SSS SS S + ++ + + S
Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 367 KTS----------QVGAASAPAKESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSE 415
+S +V + + KE+ R+G P P P K + + + S SSS
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
S S + + + S + ++ +PAK P+ PA P+K P E S
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG---------ERRS 2675
Query: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
RS + DS R++ +++ + V+ SPQ P
Sbjct: 2676 RSPRKPIDSLRDS-RSLSYSPVERRRPSPQPSP 2707
Score = 70.1 bits (170), Expect = 2e-11
Identities = 104/464 (22%), Positives = 164/464 (35%), Gaps = 44/464 (9%)
Query: 26 AAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTS 85
AA + S + V L D T L R AAL + +
Sbjct: 2264 AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
Query: 86 ESSEEEEEAEAETAKATPRLASTNSSV-------LGADLPSSMKEKAKAET-EKAGKTGN 137
SS +A A PR A + V A P+S+ A A T
Sbjct: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
Query: 138 SMPHPA----TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSA 193
+P A +G+T LL R + + + SE S G A ++
Sbjct: 2384 RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS-SRMGQAPSQSLLPP 2442
Query: 194 GQADSSSEDTSSSSDE--------TDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG-- 243
Q S S+ SD+ T V G S+ V ++ S + + PAPG
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Query: 244 --KVGDVTPQVKGGALPPAKRAKKPEEE---SESSEEGSESEEEAPAGTRSQVKASEKIL 298
VG+ P G P A A +P +E S SS S S + + + S +
Sbjct: 2503 HSDVGE-PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
Query: 299 QVRAASAPAKGTPGKGATPAP-PGKAGAV----------ASQTKAGKPEEDSESSSEESS 347
+S P + P+P P AV A + + S SSS SS
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621
Query: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
S + ++ + + +S +S ++ +PAK P+ PA P K P ++++ ++
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Query: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVR-AASAPAKESPRKG 450
D S +S S +P + + P R S+ ++ R+G
Sbjct: 2682 ID---SLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG 2722
Score = 42.4 bits (98), Expect = 0.003
Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 7/144 (4%)
Query: 1346 KRKLSGDQPAARTPRS------KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV 1399
K + G +PA KK ++L A G S + +S + +A+ K
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV-DGSSFDPQRRAREAKQPAPE 166
Query: 1400 KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1459
K S ++ ++ +K G + ++E+KKS K+KK + + E KK
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
Query: 1460 KAKKASTKDSESPSQKKKKKKKKT 1483
+ ++ T S+ S+ KK+K+ ++
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRS 250
Score = 39.7 bits (91), Expect = 0.022
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 29/131 (22%)
Query: 1358 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1417
TP+ KKKKK K + +R ++S +E+K S+ K
Sbjct: 184 TPKQKKKKK-------------------KKDRGRRSESSSPRRERK----KSSKKKKHRS 220
Query: 1418 EEELQKGMGTVEGGDQSNPKSK-KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKK 1476
E E +K PKSK K K K KR + K ++A ++++ DS S S
Sbjct: 221 ESESKK-----RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTS 275
Query: 1477 KKKKKKTAEQT 1487
+ + + A +T
Sbjct: 276 RSRSRSAAAKT 286
Score = 36.2 bits (82), Expect = 0.24
Identities = 58/287 (20%), Positives = 96/287 (33%), Gaps = 65/287 (22%)
Query: 1208 TPGLTPANSQA-------SKATPKLDSSPSVSSTLA--AKDDPDGKQEAKPQQAAGMLSP 1258
TPG PA ++ K +L ++ +S + + DP + Q A P
Sbjct: 111 TPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
Query: 1259 KTGGKEAASGTTP---QKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASV 1315
+ +E++S +P QK +K KK G S+
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSP------------------------- 205
Query: 1316 VKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEA 1375
+ERKK + K+ R ES+KRK P ++ KK+K
Sbjct: 206 --------RRERKK--SSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSR------ 249
Query: 1376 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSN 1435
S +P S + D AS S ++ K T G +
Sbjct: 250 STTPAPKSRRAHRSTSADSASS------------SDTSRSRSRSAAAKTHTTALAGRSPS 297
Query: 1436 PKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1482
P S + + + ++ + + +TK SP + K K KK+
Sbjct: 298 PASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKE 344
Score = 34.3 bits (77), Expect = 0.92
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 13/83 (15%)
Query: 1416 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE------KKEKKKKAKKASTKDS 1469
+P E K V S + K+KKK K+ + + ++E+KK +KK + S
Sbjct: 162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR-S 220
Query: 1470 ESPSQKKK------KKKKKTAEQ 1486
ES S+K+K K K+K+ ++
Sbjct: 221 ESESKKRKHRSPTPKSKRKSKDK 243
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 117 bits (292), Expect = 1e-25
Identities = 208/1080 (19%), Positives = 361/1080 (33%), Gaps = 123/1080 (11%)
Query: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG--QADSSSEDTSS 205
V N S S +K+ PS + + T + P K + S + S SE+ S
Sbjct: 66 VHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES 125
Query: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK 265
SS + +++ + +S + +E + +VK K+
Sbjct: 126 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKL-------------KVKDNKKNRTKKKPT 172
Query: 266 PE----EESESSEEGSESEEEAPAGTRSQ---VKASEKILQVRAASAPAKGTPGKGATPA 318
P+ +E+ S + + + P + +Q V S KI + + P P T
Sbjct: 173 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN-PRPSLPPNSDTSK 231
Query: 319 PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGA 373
+ ++ + +E + ++ + S+D +E+T +AK AK TS+V A
Sbjct: 232 ---ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 288
Query: 374 ASAPAKESPRKGAA---PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPS 430
P E+ KG A P P T P + K + S + +E AP K +
Sbjct: 289 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348
Query: 431 GKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSRSSSEESDSDR 486
P+ A + + +P PAP PA + K+ + + +
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 487 EALAAMNAAQVKPLGKSP---QVKPASTMGMGP---LGKGAGPVPPGKVGPATPSAQV-G 539
E K P +PA T P K P P + P TP
Sbjct: 409 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 468
Query: 540 KWEEDSESSSEESSDSSDGEVPTAV---APAQEKSLGNI-LQAKPTSS--PAKGPPQKAG 593
+E S ++ +E + ++ PT AP KS + PT++ PA P++
Sbjct: 469 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 528
Query: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS 653
P + A + + + + PA T + P PKK T
Sbjct: 529 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 588
Query: 654 AKVAPVRVGTQAPR----------KAGTATSPAGSSP----AVAGGTQRPAEDSSSSEES 699
K+AP AP + T T+P +P A A T + ++ E +
Sbjct: 589 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 648
Query: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQ 759
+ ++ A + KG P AP P K P K+
Sbjct: 649 PTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---------APTTPKKPAPKELAPTTTKE 699
Query: 760 EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 819
S + ++ + + +P K T + P + +A T+ P
Sbjct: 700 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAPTTLKEPAPTTPKKPAP 758
Query: 820 KQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEE 879
K+ +P+ K P + + P+ K A + P + E +
Sbjct: 759 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT----TPETPPPTTS 814
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
E T K H+ +P + +P A PTP + E S
Sbjct: 815 EVSTPTTTKEPTTIHK-----SPDESTPELSAEPTP------------------KALENS 851
Query: 940 DSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS---TPRKARASESTARS 996
+ P T A KP + +++ T + A+ T A +E T S
Sbjct: 852 PKEPGVPTTKTPA-ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 910
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA--GASSSKESSRISDGKK 1054
+ + + TQ TP + T+ T +APK + ++++ ++ + K
Sbjct: 911 KITATTTQVTSTTTQDTTP---FKITTLKTT--TLAPKVTTTKKTITTTEIMNKPEETAK 965
Query: 1055 QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQS 1114
+ AT P T+A K + K + P V + + + T+P +P S
Sbjct: 966 PKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 1025
Query: 1115 TSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGP 1174
+A R + P +K E + SED+ + +GE P H P
Sbjct: 1026 RIAEAMLQTTTRPNQTPN----SKLVEVNPKSEDAGGA------EGETPHMLLRPHVFMP 1075
Score = 114 bits (286), Expect = 5e-25
Identities = 172/875 (19%), Positives = 301/875 (34%), Gaps = 121/875 (13%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
+QTS G+++ +KT D TS+ + +AET P L +
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT- 310
Query: 114 GADLPSSMKEKAKAE-------TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
P++ KE A T K+ T P P T K+ +P + EP+
Sbjct: 311 ----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK-- 219
T PA +P + A ++ ++ + ++ + T E P+
Sbjct: 367 TP---------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 417
Query: 220 --PAQVKASSVSTKE----SPARKAAPAPGKVGDVTPQVKGGALP--PAKRAKKPEEESE 271
P K + +TKE +P A AP K TP+ P PA K +
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477
Query: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVAS 328
E + + AP T+ + K A + P + +P PAP A
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 533
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR--KGA 386
+ P+E + ++ +E + + + PA + + T + A + P K +P +
Sbjct: 534 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPEKL 591
Query: 387 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
AP P K P + A E+ ++ E + A A + K P PA +
Sbjct: 592 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 651
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE----------ALAAMNAAQ 496
P++ AP P++T P + ++ ++ + + +E + A
Sbjct: 652 PKE-PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710
Query: 497 VKPLGKSPQV--KPASTMGMGPLG---KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
P G +P +PA T P KG P + P TP K E ++
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGP 769
Query: 552 SSDSSDGEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
+S +SD PT AP K KP + + PP V+ ++P
Sbjct: 770 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 829
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
+S +ES+ +E P A+ + +P + +T A K TT + K
Sbjct: 830 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA--------------K 875
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T ++P + ++++++ E +E ++ A +
Sbjct: 876 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-------------------KITATT 916
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V + Q T P T K + + ++ E + E A P
Sbjct: 917 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD-------- 968
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
RA ++K T P K A + K P VR P+ + + +++P
Sbjct: 969 ---------RATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1019
Query: 849 SV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 880
+ + Q T P + S E + + E
Sbjct: 1020 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1054
Score = 107 bits (267), Expect = 9e-23
Identities = 196/1049 (18%), Positives = 358/1049 (34%), Gaps = 112/1049 (10%)
Query: 230 TKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKP----------------EEESESS 273
T ++KA P G + K PP K+ K +E S SS
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 129
Query: 274 EEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAG 333
S S + A+ ++ + K K TP PP V + +G
Sbjct: 130 SSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPP-----VVDEAGSG 184
Query: 334 KPEEDSESSSEESSDSE-EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 392
D + ++ ++S ++ + + + AK + S +KE+
Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244
Query: 393 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ---------AKPSGKA------PQVR 437
Q ++ +S++E+ S E+ A+ AKP+ KA P +
Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 304
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
P +P++ A+ P T +E ++ + +E
Sbjct: 305 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 364
Query: 498 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW-EEDSESSSEESSDSS 556
K P P +T P + P P + P TP +E + ++ +E + ++
Sbjct: 365 PTTPKEP--APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422
Query: 557 DGE-VPTA--VAPAQEKSLGNILQAKPTSSPAKGP----PQKAGPVAV-QVKAEKPMDNS 608
E PT AP K KP + K P P++ P + P + +
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 482
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
++ +S+ + E AP +A P P T P T A P + P K
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-K 541
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T+P +P T++PA ++ E + + ++T + + L
Sbjct: 542 EPAPTTPKEPAPTT---TKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 597
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
P + + AP P + PT + A +++ + E A +P + + K
Sbjct: 598 KPAP-TTPEELAPTTPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654
Query: 789 QAKANPAAARAPSAKG----TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGP 844
A P + KG T+ P K+ +P+ K P +
Sbjct: 655 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 845 ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK 904
+ P+ K A + P G++ + +E A T + KP+ K P
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTA--PTTLKEPAPTTPK-KPAPKELAPTTTKGPTS 771
Query: 905 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 964
+ K APT P +T P+ K+ + + + + E P TS + P +P
Sbjct: 772 TTSDK-PAPTTPKETAPTTP---KEPAPTTPKKPAPTTPETPPPTTSE--VSTPTTTKEP 825
Query: 965 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ---CLTPGIRTNV 1021
P + + A TP+ + S E +P T+ P + T
Sbjct: 826 TTIHKSPDESTPELSAEPTPK-----------ALENSPKEPGVPTTKTPAATKPEMTTTA 874
Query: 1022 VTMPTAHP-RIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
T R P+ + A +KE++ ++ K E T + + ++ K+
Sbjct: 875 KDKTTERDLRTTPETTTAAPKMTKETATTTE-KTTESKITATTTQVTSTTTQDTTPFKIT 933
Query: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATS-PQSTSVQAKGTNKLRKPKLPEVQQATKA 1139
K + P V T+ + + T+ P+ + +K T P+ Q+ TKA
Sbjct: 934 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATT-------PKPQKPTKA 986
Query: 1140 PESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPS 1199
P+ + +++ P+ K T PTP + + + E S +
Sbjct: 987 PK----------KPTSTKKPKTMPRVRKPKTT--PTPRKMTSTMPELNPTS------RIA 1028
Query: 1200 QSLLSGYMTPGLTPANSQASKATPKLDSS 1228
+++L P TP NS+ + PK + +
Sbjct: 1029 EAMLQTTTRPNQTP-NSKLVEVNPKSEDA 1056
Score = 106 bits (265), Expect = 1e-22
Identities = 193/1038 (18%), Positives = 359/1038 (34%), Gaps = 109/1038 (10%)
Query: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAE-----AETAKATPRLASTNSSV 112
EL +K K +++ + KK P E+ + + +T+ ST+ +
Sbjct: 152 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 211
Query: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSP----RKSAEPSANTT 168
A P + + ++ + +T ++ T +T + K ++ + T
Sbjct: 212 TTAK-PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 270
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV 228
+ +T + P AKP + + T T + S P + +++
Sbjct: 271 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 330
Query: 229 STKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
+ + ++ AP K TP+ P K+P + + ++E AP T+
Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTPKE-----PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
S ++ PA TP K A P A + P+E + ++ E +
Sbjct: 386 SAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKR 406
+ +E PA A K + T + A + P + +P P+P P + P K+
Sbjct: 437 TPKE-PAPTA--PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 407 EEDSQSSSEESDSEEEAPAQA---KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
+E + ++++ + + + P+ +P+ P+ A + P K +P PAP PA
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP 523
+ KP +P+ +PA T K P
Sbjct: 554 TTTK------------------------------KPAPTTPK-EPAPT-----TPKETAP 577
Query: 524 VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-S 582
P K+ P TP E ++ E + E PT P + A T
Sbjct: 578 TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 637
Query: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
PA P++ P + A + + + + + PA T + P P T
Sbjct: 638 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 697
Query: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA--EDSSSSEESD 700
P T A P P K T+P +P GT E + ++ +
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 756
Query: 701 SEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQE 760
+ +E A + KG + P + + TAP P + PT + A
Sbjct: 757 APKE---------LAPTTTKGPTSTTSDKPAP-TTPKETAPTTPKEPAPTTPKKPA---P 803
Query: 761 DSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAK 820
+ + + SE + + + T++ K+ ++ P + P+ K ++P +
Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE----PGVPT 859
Query: 821 QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV-ATAAQAQTGPEEDSGSSEEESDSEE 879
++P+ KP + R + P A + T E+ + S + ++
Sbjct: 860 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 919
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP-PGKTGPSAAQAGKQDDSGSSSEE 938
+ T P T LAP + +K T K +A + +S +++ +
Sbjct: 920 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 979
Query: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA-----------GPAATPAQAQAASTPRKA 987
+AP TS + K P +P P + A+A +T R
Sbjct: 980 PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN 1039
Query: 988 RASESTARSSSSESED----EDVIPATQCLTPGIRTNVVTMPTAH-PRIAPKASMAGASS 1042
+ S + +SED E P L P + VT + PR+ + +
Sbjct: 1040 QTPNSKLVEVNPKSEDAGGAEGETP-HMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPML 1098
Query: 1043 SKESSRISDGKKQEGPAT 1060
S E++ I +GK +G T
Sbjct: 1099 SDETN-ICNGKPVDGLTT 1115
Score = 102 bits (253), Expect = 4e-21
Identities = 218/1015 (21%), Positives = 354/1015 (34%), Gaps = 125/1015 (12%)
Query: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA------AAQVQVGKQE 472
+E P S KAP AS K + ++ P +KT + V + +
Sbjct: 64 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ 123
Query: 473 EDSRSSSEESDSD--REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 530
E S SSS S S R+ ++ N+A + L K +VK K P
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK--------KNRTKKKPTPKP 175
Query: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
P A G D + ++ ++S + +V T+ K + P S +K
Sbjct: 176 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 235
Query: 591 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK---PALKIPQTKACPKK 647
E N ++S + + S + ++ AK P K+ K PK
Sbjct: 236 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV-LAKPTPKA 294
Query: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP-AVAGGTQRPAEDSSSSEESDSEEEKT 706
TT + + T K +T+P +P + P E + ++ +S K
Sbjct: 295 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 354
Query: 707 GLAVTVGQ-----AKSVGKGLQVKAASVPVKG--SLGQGTAPVLPGKTGPTVTQVKA--E 757
T + K + A K + + AP P K PT + A
Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414
Query: 758 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 817
+E + ++ +E +P K K P + P A T P T
Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP-APTTPKEPAPTTT--- 470
Query: 818 QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--- 874
K+ SP+ K P S A + A T A T P+E S ++ +E
Sbjct: 471 --KEPSPTTPKEPAPTTTKS-------APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--RKGAAPTPPGKTGP-----SAAQAG 927
+ +E A T + KP+ T + A P + +P K APT P + P +A
Sbjct: 522 TTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580
Query: 928 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN-RSPAGPAATPAQAQAASTPRK 986
K+ + + + + E PA T ++ P +P +P PA T +A A +TP++
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638
Query: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM----PTAHPRIAPKASMAGASS 1042
+ + ++ E P T T T+ PT + APK +A ++
Sbjct: 639 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTT 697
Query: 1043 SKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDS 1102
+ +S D PA K + P A P++ +
Sbjct: 698 KEPTSTTCD-----KPAPTTPKGTAPTTPKEPA--------------------PTTPKEP 732
Query: 1103 AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEG 1162
A T T+P + A T K PK TK P S+ + D ++ E
Sbjct: 733 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTST--TSDKPAPTTPKETAPTT 789
Query: 1163 PQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLS-GYMTPGLT-PANSQASK 1220
P+ P P+ ET T+ S+ P+ S TP L+ +A +
Sbjct: 790 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 849
Query: 1221 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTG------GKEAASGTTPQKS 1274
+PK P+ + A K + + K + +P+T KE A TT +K+
Sbjct: 850 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA--TTTEKT 907
Query: 1275 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1334
+ K A Q ++ Q P+ + + KV T KK + TT
Sbjct: 908 TESKITATTTQVTSTTTQDT-------TPFKITTLKTTTLAPKVTT------TKKTI-TT 953
Query: 1335 KESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1389
E K E+ K K A TP+ +K K +P+K ++T K K
Sbjct: 954 TEIMNKPEETAKPKDRATNSKATTPKPQKPTK-----------APKKPTSTKKPK 997
Score = 100 bits (249), Expect = 1e-20
Identities = 205/1028 (19%), Positives = 346/1028 (33%), Gaps = 133/1028 (12%)
Query: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
+S+K AS K T + +P PP K EE S S ++ESS S
Sbjct: 74 SSKKAPPPSGASQTIKSTTKR--SPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 131
Query: 353 TPAAKALLQAKASGKTSQVGAASAPAK-ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
+ ++ + + K+S ++ K + +K P P V +A +G D +
Sbjct: 132 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 191
Query: 412 SSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 468
++ ++ + + P + K R + P ++ ++ + T
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 251
Query: 469 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK---SPQVKPASTMGMGPLGKGAGPVP 525
KQ S + +++ +A + P K P K +T KG
Sbjct: 252 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT------KGPALTT 305
Query: 526 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI-LQAKPTSSP 584
P + P TP ++ ++ +S+ ++ P AP KS + PT++
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTT----PKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 585 AKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE-EAPAAMTAAQAKPALKIPQTKA 643
P P K P + + A + + PA T + P T
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 421
Query: 644 CPKKTNTTAS--AKVAPVRVGTQAPRKAGTAT--SPAGSSPAVAGGTQRPAEDSSSSEES 699
PK+ T A P AP+K T PA ++P T ++ +E
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481
Query: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS--LGQGTAPVLPGKTGPTVTQVKAE 757
K+ T A + K A + P + S + AP P + PT + A
Sbjct: 482 APTTTKSAPTTTKEPAPTTTKS----APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 537
Query: 758 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 817
+ E A +P + + K A P + K T K +T
Sbjct: 538 T----------TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 818 QAKQRSPSKVKPPVRNPQN--STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 875
K + KP P+ T + P A A P+E + ++ +E
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647
Query: 876 DSEEEAETLAQVKPSGKTHQIRAALAPAKESPR--KGAAPTPPGKTGPS--AAQAGKQDD 931
E P+ T + A P +P K APT P K P A K+
Sbjct: 648 APTTPKE------PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701
Query: 932 SGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN-RSPAGPAATPAQAQAASTPRKARAS 990
S + + + + + A T + P +P +P G A T + A +TP+K
Sbjct: 702 STTCDKPAPTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 759
Query: 991 E---STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS 1047
E +T + +S + D+ P T T PT AP
Sbjct: 760 ELAPTTTKGPTSTTSDK----------PAPTTPKETAPTTPKEPAPTTP----------- 798
Query: 1048 RISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTL 1107
K+ P T P + P T SE P +P++ S +
Sbjct: 799 ------KKPAPTT------PETPPPT----------TSEVSTPTTTKEPTTIHKSPDEST 836
Query: 1108 PATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAK 1167
P S + T + N ++P +P TK P ++ ++ +E D
Sbjct: 837 PELSAEPTPKALE--NSPKEPGVP----TTKTPAATKPEMTTTAKDKTTERD-------- 882
Query: 1168 SAHTLGPTPSRTETLVEETA--AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKAT--- 1222
T T + + +ETA E + + + + + ++ T TP K T
Sbjct: 883 -LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 941
Query: 1223 PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK-PKKGA 1281
PK+ ++ +T + P+ + AKP+ A T K A+ PQK K PKK
Sbjct: 942 PKVTTTKKTITTTEIMNKPE--ETAKPKDRA------TNSK--ATTPKPQKPTKAPKKPT 991
Query: 1282 GNPQASTL 1289
+ T+
Sbjct: 992 STKKPKTM 999
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 117 bits (292), Expect = 1e-25
Identities = 208/1080 (19%), Positives = 361/1080 (33%), Gaps = 123/1080 (11%)
Query: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG--QADSSSEDTSS 205
V N S S +K+ PS + + T + P K + S + S SE+ S
Sbjct: 107 VHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES 166
Query: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK 265
SS + +++ + +S + +E + +VK K+
Sbjct: 167 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKL-------------KVKDNKKNRTKKKPT 213
Query: 266 PE----EESESSEEGSESEEEAPAGTRSQ---VKASEKILQVRAASAPAKGTPGKGATPA 318
P+ +E+ S + + + P + +Q V S KI + + P P T
Sbjct: 214 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN-PRPSLPPNSDTSK 272
Query: 319 PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGA 373
+ ++ + +E + ++ + S+D +E+T +AK AK TS+V A
Sbjct: 273 ---ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 329
Query: 374 ASAPAKESPRKGAA---PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPS 430
P E+ KG A P P T P + K + S + +E AP K +
Sbjct: 330 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389
Query: 431 GKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSRSSSEESDSDR 486
P+ A + + +P PAP PA + K+ + + +
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 487 EALAAMNAAQVKPLGKSP---QVKPASTMGMGP---LGKGAGPVPPGKVGPATPSAQV-G 539
E K P +PA T P K P P + P TP
Sbjct: 450 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 509
Query: 540 KWEEDSESSSEESSDSSDGEVPTAV---APAQEKSLGNI-LQAKPTSS--PAKGPPQKAG 593
+E S ++ +E + ++ PT AP KS + PT++ PA P++
Sbjct: 510 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 569
Query: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS 653
P + A + + + + PA T + P PKK T
Sbjct: 570 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 629
Query: 654 AKVAPVRVGTQAPR----------KAGTATSPAGSSP----AVAGGTQRPAEDSSSSEES 699
K+AP AP + T T+P +P A A T + ++ E +
Sbjct: 630 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 689
Query: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQ 759
+ ++ A + KG P AP P K P K+
Sbjct: 690 PTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---------APTTPKKPAPKELAPTTTKE 740
Query: 760 EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 819
S + ++ + + +P K T + P + +A T+ P
Sbjct: 741 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAPTTLKEPAPTTPKKPAP 799
Query: 820 KQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEE 879
K+ +P+ K P + + P+ K A + P + E +
Sbjct: 800 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT----TPETPPPTTS 855
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
E T K H+ +P + +P A PTP + E S
Sbjct: 856 EVSTPTTTKEPTTIHK-----SPDESTPELSAEPTP------------------KALENS 892
Query: 940 DSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS---TPRKARASESTARS 996
+ P T A KP + +++ T + A+ T A +E T S
Sbjct: 893 PKEPGVPTTKTPA-ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 951
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA--GASSSKESSRISDGKK 1054
+ + + TQ TP + T+ T +APK + ++++ ++ + K
Sbjct: 952 KITATTTQVTSTTTQDTTP---FKITTLKTT--TLAPKVTTTKKTITTTEIMNKPEETAK 1006
Query: 1055 QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQS 1114
+ AT P T+A K + K + P V + + + T+P +P S
Sbjct: 1007 PKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 1066
Query: 1115 TSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGP 1174
+A R + P +K E + SED+ + +GE P H P
Sbjct: 1067 RIAEAMLQTTTRPNQTPN----SKLVEVNPKSEDAGGA------EGETPHMLLRPHVFMP 1116
Score = 114 bits (286), Expect = 5e-25
Identities = 172/875 (19%), Positives = 301/875 (34%), Gaps = 121/875 (13%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
+QTS G+++ +KT D TS+ + +AET P L +
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT- 351
Query: 114 GADLPSSMKEKAKAE-------TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
P++ KE A T K+ T P P T K+ +P + EP+
Sbjct: 352 ----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK-- 219
T PA +P + A ++ ++ + ++ + T E P+
Sbjct: 408 TP---------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 458
Query: 220 --PAQVKASSVSTKE----SPARKAAPAPGKVGDVTPQVKGGALP--PAKRAKKPEEESE 271
P K + +TKE +P A AP K TP+ P PA K +
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 518
Query: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVAS 328
E + + AP T+ + K A + P + +P PAP A
Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 574
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR--KGA 386
+ P+E + ++ +E + + + PA + + T + A + P K +P +
Sbjct: 575 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPEKL 632
Query: 387 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
AP P K P + A E+ ++ E + A A + K P PA +
Sbjct: 633 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 692
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE----------ALAAMNAAQ 496
P++ AP P++T P + ++ ++ + + +E + A
Sbjct: 693 PKE-PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751
Query: 497 VKPLGKSPQV--KPASTMGMGPLG---KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
P G +P +PA T P KG P + P TP K E ++
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGP 810
Query: 552 SSDSSDGEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
+S +SD PT AP K KP + + PP V+ ++P
Sbjct: 811 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 870
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
+S +ES+ +E P A+ + +P + +T A K TT + K
Sbjct: 871 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA--------------K 916
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T ++P + ++++++ E +E ++ A +
Sbjct: 917 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-------------------KITATT 957
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V + Q T P T K + + ++ E + E A P
Sbjct: 958 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD-------- 1009
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
RA ++K T P K A + K P VR P+ + + +++P
Sbjct: 1010 ---------RATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1060
Query: 849 SV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 880
+ + Q T P + S E + + E
Sbjct: 1061 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1095
Score = 107 bits (267), Expect = 9e-23
Identities = 196/1049 (18%), Positives = 358/1049 (34%), Gaps = 112/1049 (10%)
Query: 230 TKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKP----------------EEESESS 273
T ++KA P G + K PP K+ K +E S SS
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 170
Query: 274 EEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAG 333
S S + A+ ++ + K K TP PP V + +G
Sbjct: 171 SSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPP-----VVDEAGSG 225
Query: 334 KPEEDSESSSEESSDSE-EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 392
D + ++ ++S ++ + + + AK + S +KE+
Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 285
Query: 393 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ---------AKPSGKA------PQVR 437
Q ++ +S++E+ S E+ A+ AKP+ KA P +
Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 345
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
P +P++ A+ P T +E ++ + +E
Sbjct: 346 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 405
Query: 498 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW-EEDSESSSEESSDSS 556
K P P +T P + P P + P TP +E + ++ +E + ++
Sbjct: 406 PTTPKEP--APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463
Query: 557 DGE-VPTA--VAPAQEKSLGNILQAKPTSSPAKGP----PQKAGPVAV-QVKAEKPMDNS 608
E PT AP K KP + K P P++ P + P + +
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 523
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
++ +S+ + E AP +A P P T P T A P + P K
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-K 582
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T+P +P T++PA ++ E + + ++T + + L
Sbjct: 583 EPAPTTPKEPAPTT---TKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 638
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
P + + AP P + PT + A +++ + E A +P + + K
Sbjct: 639 KPAP-TTPEELAPTTPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695
Query: 789 QAKANPAAARAPSAKG----TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGP 844
A P + KG T+ P K+ +P+ K P +
Sbjct: 696 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 845 ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK 904
+ P+ K A + P G++ + +E A T + KP+ K P
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTA--PTTLKEPAPTTPK-KPAPKELAPTTTKGPTS 812
Query: 905 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 964
+ K APT P +T P+ K+ + + + + E P TS + P +P
Sbjct: 813 TTSDK-PAPTTPKETAPTTP---KEPAPTTPKKPAPTTPETPPPTTSE--VSTPTTTKEP 866
Query: 965 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ---CLTPGIRTNV 1021
P + + A TP+ + S E +P T+ P + T
Sbjct: 867 TTIHKSPDESTPELSAEPTPK-----------ALENSPKEPGVPTTKTPAATKPEMTTTA 915
Query: 1022 VTMPTAHP-RIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
T R P+ + A +KE++ ++ K E T + + ++ K+
Sbjct: 916 KDKTTERDLRTTPETTTAAPKMTKETATTTE-KTTESKITATTTQVTSTTTQDTTPFKIT 974
Query: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATS-PQSTSVQAKGTNKLRKPKLPEVQQATKA 1139
K + P V T+ + + T+ P+ + +K T P+ Q+ TKA
Sbjct: 975 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATT-------PKPQKPTKA 1027
Query: 1140 PESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPS 1199
P+ + +++ P+ K T PTP + + + E S +
Sbjct: 1028 PK----------KPTSTKKPKTMPRVRKPKTT--PTPRKMTSTMPELNPTS------RIA 1069
Query: 1200 QSLLSGYMTPGLTPANSQASKATPKLDSS 1228
+++L P TP NS+ + PK + +
Sbjct: 1070 EAMLQTTTRPNQTP-NSKLVEVNPKSEDA 1097
Score = 106 bits (265), Expect = 1e-22
Identities = 193/1038 (18%), Positives = 359/1038 (34%), Gaps = 109/1038 (10%)
Query: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAE-----AETAKATPRLASTNSSV 112
EL +K K +++ + KK P E+ + + +T+ ST+ +
Sbjct: 193 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 252
Query: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSP----RKSAEPSANTT 168
A P + + ++ + +T ++ T +T + K ++ + T
Sbjct: 253 TTAK-PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 311
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV 228
+ +T + P AKP + + T T + S P + +++
Sbjct: 312 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 371
Query: 229 STKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
+ + ++ AP K TP+ P K+P + + ++E AP T+
Sbjct: 372 KSAPTTPKEPAPTTTKSAPTTPKE-----PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
S ++ PA TP K A P A + P+E + ++ E +
Sbjct: 427 SAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKR 406
+ +E PA A K + T + A + P + +P P+P P + P K+
Sbjct: 478 TPKE-PAPTA--PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 407 EEDSQSSSEESDSEEEAPAQA---KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
+E + ++++ + + + P+ +P+ P+ A + P K +P PAP PA
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP 523
+ KP +P+ +PA T K P
Sbjct: 595 TTTK------------------------------KPAPTTPK-EPAPT-----TPKETAP 618
Query: 524 VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-S 582
P K+ P TP E ++ E + E PT P + A T
Sbjct: 619 TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 678
Query: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
PA P++ P + A + + + + + PA T + P P T
Sbjct: 679 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 738
Query: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA--EDSSSSEESD 700
P T A P P K T+P +P GT E + ++ +
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 797
Query: 701 SEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQE 760
+ +E A + KG + P + + TAP P + PT + A
Sbjct: 798 APKE---------LAPTTTKGPTSTTSDKPAP-TTPKETAPTTPKEPAPTTPKKPA---P 844
Query: 761 DSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAK 820
+ + + SE + + + T++ K+ ++ P + P+ K ++P +
Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE----PGVPT 900
Query: 821 QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV-ATAAQAQTGPEEDSGSSEEESDSEE 879
++P+ KP + R + P A + T E+ + S + ++
Sbjct: 901 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 960
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP-PGKTGPSAAQAGKQDDSGSSSEE 938
+ T P T LAP + +K T K +A + +S +++ +
Sbjct: 961 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 1020
Query: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA-----------GPAATPAQAQAASTPRKA 987
+AP TS + K P +P P + A+A +T R
Sbjct: 1021 PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN 1080
Query: 988 RASESTARSSSSESED----EDVIPATQCLTPGIRTNVVTMPTAH-PRIAPKASMAGASS 1042
+ S + +SED E P L P + VT + PR+ + +
Sbjct: 1081 QTPNSKLVEVNPKSEDAGGAEGETP-HMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPML 1139
Query: 1043 SKESSRISDGKKQEGPAT 1060
S E++ I +GK +G T
Sbjct: 1140 SDETN-ICNGKPVDGLTT 1156
Score = 102 bits (253), Expect = 4e-21
Identities = 218/1015 (21%), Positives = 354/1015 (34%), Gaps = 125/1015 (12%)
Query: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA------AAQVQVGKQE 472
+E P S KAP AS K + ++ P +KT + V + +
Sbjct: 105 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ 164
Query: 473 EDSRSSSEESDSD--REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 530
E S SSS S S R+ ++ N+A + L K +VK K P
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK--------KNRTKKKPTPKP 216
Query: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
P A G D + ++ ++S + +V T+ K + P S +K
Sbjct: 217 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 276
Query: 591 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK---PALKIPQTKACPKK 647
E N ++S + + S + ++ AK P K+ K PK
Sbjct: 277 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV-LAKPTPKA 335
Query: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP-AVAGGTQRPAEDSSSSEESDSEEEKT 706
TT + + T K +T+P +P + P E + ++ +S K
Sbjct: 336 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 395
Query: 707 GLAVTVGQ-----AKSVGKGLQVKAASVPVKG--SLGQGTAPVLPGKTGPTVTQVKA--E 757
T + K + A K + + AP P K PT + A
Sbjct: 396 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455
Query: 758 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 817
+E + ++ +E +P K K P + P A T P T
Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP-APTTPKEPAPTTT--- 511
Query: 818 QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--- 874
K+ SP+ K P S A + A T A T P+E S ++ +E
Sbjct: 512 --KEPSPTTPKEPAPTTTKS-------APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--RKGAAPTPPGKTGP-----SAAQAG 927
+ +E A T + KP+ T + A P + +P K APT P + P +A
Sbjct: 563 TTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621
Query: 928 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN-RSPAGPAATPAQAQAASTPRK 986
K+ + + + + E PA T ++ P +P +P PA T +A A +TP++
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679
Query: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM----PTAHPRIAPKASMAGASS 1042
+ + ++ E P T T T+ PT + APK +A ++
Sbjct: 680 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTT 738
Query: 1043 SKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDS 1102
+ +S D PA K + P A P++ +
Sbjct: 739 KEPTSTTCD-----KPAPTTPKGTAPTTPKEPA--------------------PTTPKEP 773
Query: 1103 AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEG 1162
A T T+P + A T K PK TK P S+ + D ++ E
Sbjct: 774 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTST--TSDKPAPTTPKETAPTT 830
Query: 1163 PQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLS-GYMTPGLT-PANSQASK 1220
P+ P P+ ET T+ S+ P+ S TP L+ +A +
Sbjct: 831 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 890
Query: 1221 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTG------GKEAASGTTPQKS 1274
+PK P+ + A K + + K + +P+T KE A TT +K+
Sbjct: 891 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA--TTTEKT 948
Query: 1275 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1334
+ K A Q ++ Q P+ + + KV T KK + TT
Sbjct: 949 TESKITATTTQVTSTTTQDT-------TPFKITTLKTTTLAPKVTT------TKKTI-TT 994
Query: 1335 KESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1389
E K E+ K K A TP+ +K K +P+K ++T K K
Sbjct: 995 TEIMNKPEETAKPKDRATNSKATTPKPQKPTK-----------APKKPTSTKKPK 1038
Score = 100 bits (249), Expect = 1e-20
Identities = 205/1028 (19%), Positives = 346/1028 (33%), Gaps = 133/1028 (12%)
Query: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
+S+K AS K T + +P PP K EE S S ++ESS S
Sbjct: 115 SSKKAPPPSGASQTIKSTTKR--SPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 172
Query: 353 TPAAKALLQAKASGKTSQVGAASAPAK-ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
+ ++ + + K+S ++ K + +K P P V +A +G D +
Sbjct: 173 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 232
Query: 412 SSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 468
++ ++ + + P + K R + P ++ ++ + T
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 292
Query: 469 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK---SPQVKPASTMGMGPLGKGAGPVP 525
KQ S + +++ +A + P K P K +T KG
Sbjct: 293 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT------KGPALTT 346
Query: 526 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI-LQAKPTSSP 584
P + P TP ++ ++ +S+ ++ P AP KS + PT++
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTT----PKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 585 AKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE-EAPAAMTAAQAKPALKIPQTKA 643
P P K P + + A + + PA T + P T
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 462
Query: 644 CPKKTNTTAS--AKVAPVRVGTQAPRKAGTAT--SPAGSSPAVAGGTQRPAEDSSSSEES 699
PK+ T A P AP+K T PA ++P T ++ +E
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522
Query: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS--LGQGTAPVLPGKTGPTVTQVKAE 757
K+ T A + K A + P + S + AP P + PT + A
Sbjct: 523 APTTTKSAPTTTKEPAPTTTKS----APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 578
Query: 758 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 817
+ E A +P + + K A P + K T K +T
Sbjct: 579 T----------TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 818 QAKQRSPSKVKPPVRNPQN--STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 875
K + KP P+ T + P A A P+E + ++ +E
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688
Query: 876 DSEEEAETLAQVKPSGKTHQIRAALAPAKESPR--KGAAPTPPGKTGPS--AAQAGKQDD 931
E P+ T + A P +P K APT P K P A K+
Sbjct: 689 APTTPKE------PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742
Query: 932 SGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN-RSPAGPAATPAQAQAASTPRKARAS 990
S + + + + + A T + P +P +P G A T + A +TP+K
Sbjct: 743 STTCDKPAPTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 800
Query: 991 E---STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS 1047
E +T + +S + D+ P T T PT AP
Sbjct: 801 ELAPTTTKGPTSTTSDK----------PAPTTPKETAPTTPKEPAPTTP----------- 839
Query: 1048 RISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTL 1107
K+ P T P + P T SE P +P++ S +
Sbjct: 840 ------KKPAPTT------PETPPPT----------TSEVSTPTTTKEPTTIHKSPDEST 877
Query: 1108 PATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAK 1167
P S + T + N ++P +P TK P ++ ++ +E D
Sbjct: 878 PELSAEPTPKALE--NSPKEPGVP----TTKTPAATKPEMTTTAKDKTTERD-------- 923
Query: 1168 SAHTLGPTPSRTETLVEETA--AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKAT--- 1222
T T + + +ETA E + + + + + ++ T TP K T
Sbjct: 924 -LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 982
Query: 1223 PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK-PKKGA 1281
PK+ ++ +T + P+ + AKP+ A T K A+ PQK K PKK
Sbjct: 983 PKVTTTKKTITTTEIMNKPE--ETAKPKDRA------TNSK--ATTPKPQKPTKAPKKPT 1032
Query: 1282 GNPQASTL 1289
+ T+
Sbjct: 1033 STKKPKTM 1040
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 115 bits (288), Expect = 3e-25
Identities = 155/595 (26%), Positives = 241/595 (40%), Gaps = 98/595 (16%)
Query: 159 KSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSS-SDETDVEGKPS 217
+ E + T V+E EE+ + G + G +A+ E+T S ++E K +
Sbjct: 459 EQTEETQVTEEVTEEEEKEAKEEEGKEEEGG--EEEEAEGGEEETKSPPAEEAASPEKEA 516
Query: 218 VKPAQVKASSVSTKESPARKAAPAPGKVGDV----TPQVKGGALPPAKRAKKPEEESESS 273
P + +A S + +SP ++ A +P +V +P + PP AK PE+E S
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP--EAKSPEKEEAKS 574
Query: 274 EEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGA-----VAS 328
+S E+A + + + K+ + A +P K A P K A V S
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Query: 329 QTKAGKPEEDSESSSEE--SSDSEEETPAAKALLQAKASGKTSQVGA------------A 374
KA P ++ S E+ S + EE KA KA K+ + A
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 375 SAPAKE---SPRKGAAPAPPGKTGPAVAKA----QAGKREEDSQSSSEESDSEEEA--PA 425
+P KE SP K +P P AK+ +A E+ EE+ S E+A P
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754
Query: 426 QAK------PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
+AK P K P A +PA + P K +P P A+ + +ED+++
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL---KEDAKAPE 811
Query: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV----GPATPS 535
+E E + VK K +VK PP K PATP
Sbjct: 812 KEIPKKEEV-----KSPVKEEEKPQEVKVKE--------------PPKKAEEEKAPATP- 851
Query: 536 AQVGKWEEDSESSSEES--SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK---GPPQ 590
K EE +S EE+ ++ +V PA EK + ++AK + K P+
Sbjct: 852 ----KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907
Query: 591 KAGPVAVQVKAE-KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
K P V+VK + KP + +E +++ D A ++E +KPA K +A P+K +
Sbjct: 908 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE--------PSKPAEK---KEAAPEKKD 956
Query: 650 T-TASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEESDSE 702
T AK + T+A K T S S P AE SSS+++ DS+
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA-----EKAEKSSSTDQKDSK 1006
Score = 114 bits (285), Expect = 7e-25
Identities = 148/650 (22%), Positives = 242/650 (37%), Gaps = 106/650 (16%)
Query: 542 EEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA 601
EE+ E+ EE + GE +E++ G + K + P+K V+ +A
Sbjct: 473 EEEKEAKEEEGKEEEGGE--------EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA 524
Query: 602 EKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRV 661
+ P + +E + S ++P + + A P+ K+ P+K + A+V
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS-PEKEEAKSPAEV----- 578
Query: 662 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 721
++P KA + SPA A ++ S EE+ S E
Sbjct: 579 --KSPEKAKSPAKEEAKSPAEAKSPEKAK--SPVKEEAKSPAE----------------- 617
Query: 722 LQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE-EESDSEEAAASPAQ 780
A PVK + A V + + T+ +A+ E ++S E EE+ S E A SP
Sbjct: 618 -----AKSPVKEE-AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP-- 669
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VK K + +P A A S + S + + +SP K K PV+ S
Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSP--------VKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
A+ P K A + P ++ S E++ S E+A+TL P KT A
Sbjct: 722 AKSPV------KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
+PA + P K +P P A++ ++D+ + +E E
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV--------------- 820
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
+SP P + + P+KA ++ A + E +D A + P
Sbjct: 821 -----KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAP----- 870
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
P++ K A KES + KK+E + KK P A ++V
Sbjct: 871 -------KPKVEEKKEPA-VEKPKESK--VEAKKEE---AEDKKKVPTPEKEAPAKVEVK 917
Query: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPA-TSPQSTSVQAKGTNKLRKPKLPEVQQATKA 1139
+ + VA+ +P D A P+ + + + K K K K PE + T+A
Sbjct: 918 EDAKPKEKTEVAKKEP----DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEA 973
Query: 1140 PESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAE 1189
DD S + S E E KS+ T E E+ AA+
Sbjct: 974 KAKEDDKTLSKEPSKPKAEKAE-----KSSSTDQKDSKPPEKATEDKAAK 1018
Score = 110 bits (274), Expect = 1e-23
Identities = 150/690 (21%), Positives = 254/690 (36%), Gaps = 102/690 (14%)
Query: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK-ASEKILQVRA 302
K+ V+ +K + K +K E+E+ EE +E + T + K A E+ +
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 303 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA 362
+ G+ T +PP + A + +E+++S +E S +EE + +
Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP 547
Query: 363 KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 422
+ + ++ A S P +SP K A +P P AK+ A ++ S E+ S E+
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA----KEEAKSPAEAKSPEK 603
Query: 423 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 482
A + K K+P A +P KE + A P K + + + E+ EE+
Sbjct: 604 AKSPVKEEAKSP--AEAKSPVKEEAKSPAEVKSPEK-AKSPTKEEAKSPEKAKSPEKEEA 660
Query: 483 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 542
S +A + VK KSP+ K PV P
Sbjct: 661 KSPEKA-----KSPVKAEAKSPE-------------KAKSPVKAEAKSP----------- 691
Query: 543 EDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE 602
E ++S +E + S + A +P +E++ P AK P + PV + K+
Sbjct: 692 EKAKSPVKEEAKSPE----KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747
Query: 603 KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVG 662
+ + E ++ + + PA A PA K P+ AK +PV+
Sbjct: 748 EKAKSPEKAKTLDVKSPEAKTPAKEEA--RSPADKFPE------------KAK-SPVKEE 792
Query: 663 TQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
++P KA SP ED+ + E+ ++E+ V K K
Sbjct: 793 VKSPEKA--------KSPL--------KEDAKAPEKEIPKKEEVKSPV-----KEEEKPQ 831
Query: 723 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
+VK P K + A P + K K+E++ E E PA K
Sbjct: 832 EVKVKEPPKKAEEEKAPAT-------PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 783 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
K +AK A K + P K A + K+ + K K V + A+
Sbjct: 885 PKESKVEAKKEEA-----EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAK 939
Query: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
P+ A + + PE+ E+ EE+ +T A+ K KT +
Sbjct: 940 EPSK---------PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Query: 903 AKESPRKGAA----PTPPGKTGPSAAQAGK 928
A+++ + + PP K A GK
Sbjct: 991 AEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 102 bits (253), Expect = 4e-21
Identities = 137/672 (20%), Positives = 252/672 (37%), Gaps = 94/672 (13%)
Query: 811 KVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA----AQAQTGPEE 866
K+ + + K +S K+K V + TV+ V + V A+ + G EE
Sbjct: 428 KIPSVSTHIKVKSEEKIKV-VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 867 DSGSSEEESDSEEE-----AETLAQVKPSGKTHQIRAALAPAK-ESPRKGAAPTPPGKTG 920
+ G EE EEE AE A + K+ A +PA+ +SP K A +P
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 921 PSAAQAGKQDDSGSSSEESDSDGE---APAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
P A++ ++++ S E + E +PA V S + K P A +PA+
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA---------KEEAKSPAE 597
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM 1037
A++ + E+ + + + E+ + +P PT +P+ +
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP----EKAKSPTKEEAKSPEKA- 652
Query: 1038 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1097
S E +K + P + K+P ++ +K A+ +A+ PV S
Sbjct: 653 ----KSPEKEEAKSPEKAKSPV-KAEAKSPEK---AKSPVKAEAKSPEKAKSPVKEEAKS 704
Query: 1098 SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE 1157
P + +AK K + P V++ K PE + S +
Sbjct: 705 ----------PEKAKSPVKEEAKSPEKAKSP----VKEEAKTPEKA---------KSPVK 741
Query: 1158 EDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQ 1217
E+ + P+ AKS P ++T + A ++++ +P+ +P S
Sbjct: 742 EEAKSPEKAKS-----PEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796
Query: 1218 ASKATPKLDSSPSVSSTLAAKDDPDG--KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSR 1275
+P + + + + K++ K+E KPQ+ PK +E A T + +
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 1276 KPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTK 1335
K K P+ P P E + + +V K +E ++++ D K
Sbjct: 857 KDSKKEEAPKKEA--------------PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Query: 1336 ESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKA 1395
+ + K ++ D + K+K ++ E +A K A K
Sbjct: 903 VPTPEKEAPAKVEVKEDA------KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 1396 SGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKK 1455
+ + K KK + ++ E ++ L K + S PK++K +K S +KD +
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDKTLSK--------EPSKPKAEKAEKSSSTDQKDSKPP 1008
Query: 1456 EKKKKAKKASTK 1467
EK + K A K
Sbjct: 1009 EKATEDKAAKGK 1020
Score = 95.1 bits (235), Expect = 4e-19
Identities = 129/551 (23%), Positives = 202/551 (36%), Gaps = 66/551 (11%)
Query: 66 EEDAALQAKKTRVSDPISTSESSEEE------EEAEAETAKATPRLASTNSSVLGADLPS 119
EE+ A ++ S P + S E+E EEA++ +P S A++ S
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSP---AEVKS 546
Query: 120 SMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSV 179
K K+ A+ E P K+ A + S + + A+ A + +++ E+
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 180 PAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK---PAQVKASSVSTK 231
P A P + + + S E T E K K P + +A S
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG-SESEEEAPAGTRSQ 290
+SP + A +P K VK A P K +EE++S E+ S +EEA + +++
Sbjct: 667 KSPVKAEAKSPEKAKS---PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723
Query: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350
E+ A +P K P KA + ++ K E+ S E
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 351 EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP---PGKTGPAVAKAQAGKRE 407
+ K +++ K+ A AP KE P+K +P K K K E
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE 843
Query: 408 ED----SQSSSEESDSE-EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA-------- 454
E+ + + E+ DS+ EEAP + P P+V PA E P++ A
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKEAPK---PKVEEKKEPAVEKPKESKVEAKKEEAEDK 900
Query: 455 ----PPRKTGPAAAQV----------QVGKQEEDSRSSSEESDSDREALAAMNAAQVK-P 499
P K PA +V +V K+E D + E S + AA K
Sbjct: 901 KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960
Query: 500 LGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGE 559
K P+ KP + K P+ P A E+ +SSS + DS E
Sbjct: 961 KAKKPEEKPKTE------AKAKEDDKTLSKEPSKPKA-----EKAEKSSSTDQKDSKPPE 1009
Query: 560 VPTAVAPAQEK 570
T A+ K
Sbjct: 1010 KATEDKAAKGK 1020
Score = 92.8 bits (229), Expect = 2e-18
Identities = 127/568 (22%), Positives = 220/568 (38%), Gaps = 78/568 (13%)
Query: 751 VTQVKAEKQEDSESSEEESDSE---------------EAAASPAQVKTSVKKTQAKANPA 795
VT+ + ++ ++ E EEE E E AASP + S K +AK +PA
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAK-SPA 528
Query: 796 AARAPSAKGTISAPGKVVT-AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
A++P K +P +V + A++ + +K P ++P+ A+ PA V S KA
Sbjct: 529 EAKSPE-KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE--AKSPAEVKSPEKAK 585
Query: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK-ESPRKGAAP 913
+ A + P E + +S +EEA++ A+ K K A +PA+ +SP K +P
Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK----EEAKSPAEVKSPEKAKSP 641
Query: 914 TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 973
T P A++ +++++ S E++ S +A A +SP A
Sbjct: 642 TKEEAKSPEKAKSPEKEEA-KSPEKAKSPVKAEA------------------KSPE-KAK 681
Query: 974 TPAQAQAASTPRKARA--SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI 1031
+P +A+A S P KA++ E ++S ++ + + ++ T A +
Sbjct: 682 SPVKAEAKS-PEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740
Query: 1032 APKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPV 1091
+A + S E ++ D K P + K A P + K + E + P
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVK---SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797
Query: 1092 ARTQP-SSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1150
P + +P + V+ + + K K P + + ++ +E+
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK 857
Query: 1151 DSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG 1210
DS E P+ K P + + E E +ED P
Sbjct: 858 DSKKEEAPKKEAPK-PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVP------------ 904
Query: 1211 LTPANSQASKATPKLDSSPSVSSTLAAK--DDPDGKQEAKPQQAAGMLSPKTGGKEAASG 1268
TP +K K D+ P + +A K DD K+ +KP + KEAA
Sbjct: 905 -TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK----------KEAAPE 953
Query: 1269 TTPQKSRKPKKGAGNPQASTLALQSNIT 1296
K K KK P+ A + + T
Sbjct: 954 KKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Score = 76.6 bits (187), Expect = 2e-13
Identities = 110/510 (21%), Positives = 200/510 (39%), Gaps = 78/510 (15%)
Query: 1019 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSK---KNPASLPLTQA 1075
T +V T ++ + + +KE +GK++EG + ++ + S P +A
Sbjct: 454 TVIVEEQTEETQVTEEVTEEEEKEAKEE----EGKEEEGGEEEEAEGGEEETKSPPAEEA 509
Query: 1076 ALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKP---KLPE 1132
A EA+ PV S PA + +AK +++ P K P
Sbjct: 510 A-----SPEKEAKSPVKEEAKS----------PAEAKSPEKEEAKSPAEVKSPEKAKSPA 554
Query: 1133 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSE 1192
++A PE+ ++ + S + + + P+ AKS P ++ E + E ++
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPA----EVKSPEKAKS-----PAKEEAKSPAEAKSPEKAK 605
Query: 1193 DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA 1252
V ++S +P A S A +P+ SP+ K++ ++AK +
Sbjct: 606 SPVKEEAKSPAEA-KSPVKEEAKSPAEVKSPEKAKSPT-------KEEAKSPEKAKSPEK 657
Query: 1253 AGMLSP-KTGGKEAASGTTPQKSRKPKKG-AGNPQASTLALQSNITQCLLGQPWPLNEA- 1309
SP K A +P+K++ P K A +P+ + ++ + EA
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717
Query: 1310 --QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKL 1367
+ S VK + E+ + V + K + + + L P A+TP +K++ +
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP-AKEEARS 776
Query: 1368 GAGEGGEASVSPEKTSTTSKGKAK-------------------------RDKASGDVKEK 1402
A + E + SP K S KAK ++ +VK K
Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836
Query: 1403 KGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE-----KKEK 1457
+ + A P+ E +K E + PK K E+KK +K KE KKE+
Sbjct: 837 EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE 896
Query: 1458 KKKAKKASTKDSESPSQKKKKKKKKTAEQT 1487
+ KK T + E+P++ + K+ K E+T
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKEDAKPKEKT 926
Score = 45.4 bits (106), Expect = 4e-04
Identities = 44/191 (23%), Positives = 84/191 (43%), Gaps = 13/191 (6%)
Query: 1303 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1362
P+ L E + V ++ +E+ KVV+ +++ + E + ++ +
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 1363 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--KGSLGSQGAKDEPEEE 1420
K+++ EGGE + T A ++A+ KE K K S PE+E
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPA--EEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 1421 LQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKK--------KKAKKASTKDSESP 1472
K V+ +++ + KE+ KS K EK+E K +KAK + ++++SP
Sbjct: 537 EAKSPAEVKSPEKAKSPA-KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 1473 SQKKKKKKKKT 1483
++ K +K K+
Sbjct: 596 AEAKSPEKAKS 606
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 114 bits (286), Expect = 5e-25
Identities = 172/875 (19%), Positives = 301/875 (34%), Gaps = 121/875 (13%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
+QTS G+++ +KT D TS+ + +AET P L +
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT- 217
Query: 114 GADLPSSMKEKAKAE-------TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
P++ KE A T K+ T P P T K+ +P + EP+
Sbjct: 218 ----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK-- 219
T PA +P + A ++ ++ + ++ + T E P+
Sbjct: 274 TP---------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 324
Query: 220 --PAQVKASSVSTKE----SPARKAAPAPGKVGDVTPQVKGGALP--PAKRAKKPEEESE 271
P K + +TKE +P A AP K TP+ P PA K +
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384
Query: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVAS 328
E + + AP T+ + K A + P + +P PAP A
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 440
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR--KGA 386
+ P+E + ++ +E + + + PA + + T + A + P K +P +
Sbjct: 441 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPEKL 498
Query: 387 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
AP P K P + A E+ ++ E + A A + K P PA +
Sbjct: 499 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 558
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE----------ALAAMNAAQ 496
P++ AP P++T P + ++ ++ + + +E + A
Sbjct: 559 PKE-PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617
Query: 497 VKPLGKSPQV--KPASTMGMGPLG---KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
P G +P +PA T P KG P + P TP K E ++
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGP 676
Query: 552 SSDSSDGEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
+S +SD PT AP K KP + + PP V+ ++P
Sbjct: 677 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 736
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
+S +ES+ +E P A+ + +P + +T A K TT + K
Sbjct: 737 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA--------------K 782
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T ++P + ++++++ E +E ++ A +
Sbjct: 783 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-------------------KITATT 823
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V + Q T P T K + + ++ E + E A P
Sbjct: 824 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD-------- 875
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
RA ++K T P K A + K P VR P+ + + +++P
Sbjct: 876 ---------RATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 926
Query: 849 SV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 880
+ + Q T P + S E + + E
Sbjct: 927 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 961
Score = 109 bits (273), Expect = 2e-23
Identities = 174/883 (19%), Positives = 294/883 (33%), Gaps = 97/883 (10%)
Query: 336 EEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGAASAPAKESPRKGAA--- 387
+E + ++ + S+D +E+T +AK AK TS+V A P E+ KG A
Sbjct: 153 KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 212
Query: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
P P T P + K + S + +E AP K + P+ A + + +P
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 272
Query: 448 RKGAAPAPPRKTGPAAAQVQ----VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKS 503
PAP PA + K+ + + +E K
Sbjct: 273 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 332
Query: 504 P---QVKPASTMGMGP---LGKGAGPVPPGKVGPATPSAQV-GKWEEDSESSSEESSDSS 556
P +PA T P K P P + P TP +E S ++ +E + ++
Sbjct: 333 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392
Query: 557 DGEVPTAV---APAQEKSLGNI-LQAKPTSS--PAKGPPQKAGPVAVQVKAEKPMDNSES 610
PT AP KS + PT++ PA P++ P + A
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452
Query: 611 SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR--- 667
+ + + + PA T + P PKK T K+AP AP
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512
Query: 668 -------KAGTATSPAGSSP----AVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
+ T T+P +P A A T + ++ E + + ++ A
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572
Query: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
+ KG P AP P K P K+ S + ++ + +
Sbjct: 573 TTPKGTAPTTLKEP---------APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623
Query: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
+P K T + P + +A T+ P K+ +P+ K P +
Sbjct: 624 APTTPKEPAPTTPKEPAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682
Query: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI 896
+ P+ K A + P + E + E T K H+
Sbjct: 683 KPAPTTPKETAPTTPKEPAPTTPKKPAPT----TPETPPPTTSEVSTPTTTKEPTTIHK- 737
Query: 897 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 956
+P + +P A PTP + E S + P T A K
Sbjct: 738 ----SPDESTPELSAEPTP------------------KALENSPKEPGVPTTKTPA-ATK 774
Query: 957 PPLIFVDPNRSPAGPAATPAQAQAAS---TPRKARASESTARSSSSESEDEDVIPATQCL 1013
P + +++ T + A+ T A +E T S + + + TQ
Sbjct: 775 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDT 834
Query: 1014 TPGIRTNVVTMPTAHPRIAPKASMA--GASSSKESSRISDGKKQEGPATQVSKKNPASLP 1071
TP + T+ T +APK + ++++ ++ + K + AT P
Sbjct: 835 TP---FKITTLKTT--TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 889
Query: 1072 LTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLP 1131
T+A K + K + P V + + + T+P +P S +A R + P
Sbjct: 890 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 949
Query: 1132 EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGP 1174
+K E + SED+ + +GE P H P
Sbjct: 950 N----SKLVEVNPKSEDAGGA------EGETPHMLLRPHVFMP 982
Score = 105 bits (262), Expect = 3e-22
Identities = 192/1023 (18%), Positives = 354/1023 (34%), Gaps = 115/1023 (11%)
Query: 66 EEDAALQAKKTRVSDP-ISTSESSEEEEEAEAETAKA-TPRLASTNSSVLGADLPSSMKE 123
E + L +V+ P ST++ ++ + TAK PR + +S + ++ +
Sbjct: 87 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 146
Query: 124 KAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFG 183
+ ET++ T N + ++ + T + +T + P
Sbjct: 147 ETTVETKET--------------TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192
Query: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
AKP + + T T + S P + +++ + + ++ AP
Sbjct: 193 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 252
Query: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
K TP+ P K+P + + ++E AP T+S ++
Sbjct: 253 KSAPTTPKE-----PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE------- 300
Query: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK 363
PA TP K A P A + P+E + ++ E + + +E PA A K
Sbjct: 301 --PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTA--PKK 355
Query: 364 ASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421
+ T + A + P + +P P+P P + P K+ +E + ++++ + +
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
Query: 422 EAPAQA---KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
+ P+ +P+ P+ A + P K +P PAP PA +
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----------- 464
Query: 479 SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQV 538
KP +P+ +PA T K P P K+ P TP
Sbjct: 465 -------------------KPAPTTPK-EPAPT-----TPKETAPTTPKKLTPTTPEKLA 499
Query: 539 GKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSPAKGPPQKAGPVAV 597
E ++ E + E PT P + A T PA P++ P
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 657
+ A + + + + + PA T + P P T P T A
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 658 PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA--EDSSSSEESDSEEEKTGLAVTVGQA 715
P P K T+P +P GT E + ++ + + +E A
Sbjct: 620 PKGTAPTTP-KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---------LA 669
Query: 716 KSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 775
+ KG + P + + TAP P + PT + A + + + SE +
Sbjct: 670 PTTTKGPTSTTSDKPAP-TTPKETAPTTPKEPAPTTPKKPA---PTTPETPPPTTSEVST 725
Query: 776 ASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQ 835
+ + T++ K+ ++ P + P+ K ++P + ++P+ KP +
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE----PGVPTTKTPAATKPEMTTTA 781
Query: 836 NSTVLARGPASVPSVGKAV-ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH 894
R + P A + T E+ + S + ++ + T P T
Sbjct: 782 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 841
Query: 895 QIRAALAPAKESPRKGAAPTP-PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
LAP + +K T K +A + +S +++ + +AP TS +
Sbjct: 842 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 901
Query: 954 VIKPPLIFVDPNRSPA-----------GPAATPAQAQAASTPRKARASESTARSSSSESE 1002
K P +P P + A+A +T R + S + +SE
Sbjct: 902 KPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 961
Query: 1003 D----EDVIPATQCLTPGIRTNVVTMPTAH-PRIAPKASMAGASSSKESSRISDGKKQEG 1057
D E P L P + VT + PR+ + + S E++ I +GK +G
Sbjct: 962 DAGGAEGETP-HMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETN-ICNGKPVDG 1019
Query: 1058 PAT 1060
T
Sbjct: 1020 LTT 1022
Score = 87.4 bits (215), Expect = 9e-17
Identities = 193/950 (20%), Positives = 317/950 (33%), Gaps = 153/950 (16%)
Query: 414 SEESDSEEEAPAQAKPSGKA-PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
S E E + AQ K K P + A K++ +K P P + G
Sbjct: 36 SFERGRECDCDAQCKKYDKCCPDYESFCAEVKDN-KKNRTKKKPTPKPPVVDEAGSGLDN 94
Query: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532
D + ++ ++ + Q + SP++ A + P +PP
Sbjct: 95 GDFKVTTPDTST----------TQHNKVSTSPKITTAKPINPRP------SLPPNSDTSK 138
Query: 533 TPSAQVGKWE--EDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
S V K E E+++ S+DG E T+ Q + PTS P
Sbjct: 139 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 198
Query: 590 QKA-----GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK-- 642
KA GP K P + +E + + E P + +A P P T
Sbjct: 199 PKAETTTKGPALTTPKEPTPT----TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 643 --ACPKKTNTTASAKVAPVRVGTQAP----RKAGTATSPAGSSPAVAGGT--QRPAEDSS 694
PK+ T + + AP AP A T T A ++P T ++PA +
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 695 SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
+ +E T K + A + P + + TAP P T P
Sbjct: 315 KEPAPTTPKEPTPTT-----PKEPAPTTKEPAPTTPKEPA---PTAPKKPAPTTPKEPAP 366
Query: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
K+ +++E S + +P K++ T+ PA SA T P T
Sbjct: 367 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK---EPAPTTTKSAPTTPKEPSPTTT 423
Query: 815 AAAQAKQRSPSKVKPPV----RNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS 870
K+ +P+ K P + P +T P + P T A T P+E + +
Sbjct: 424 -----KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPAPTTTKKPAPTTPKEPAPT 477
Query: 871 SEEESD-------SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSA 923
+ +E+ + E LA P LAP P P T P A
Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 537
Query: 924 AQAG--KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAA 981
A K+ + E + + + PA T + +P G A T + A
Sbjct: 538 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT---------TPKGTAPTTLKEPAP 588
Query: 982 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 1041
+TP+K E ++ + +T C P T T PT AP A
Sbjct: 589 TTPKKPAPKELAPTTTKEPT-------STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 641
Query: 1042 SSKESSRISDGKKQ------------------EGPATQVSKKNPASLPLTQAAL------ 1077
++ + + + K+ +GP + S K + P A
Sbjct: 642 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701
Query: 1078 ------------KVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL 1125
+ SE P +P++ S + P S + T + N
Sbjct: 702 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE--NSP 759
Query: 1126 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEE 1185
++P +P TK P ++ ++ +E D T T + + +E
Sbjct: 760 KEPGVP----TTKTPAATKPEMTTTAKDKTTERD---------LRTTPETTTAAPKMTKE 806
Query: 1186 TA--AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKAT---PKLDSSPSVSSTLAAKDD 1240
TA E + + + + + ++ T TP K T PK+ ++ +T +
Sbjct: 807 TATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK 866
Query: 1241 PDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK-PKKGAGNPQASTL 1289
P+ + AKP+ A T K A+ PQK K PKK + T+
Sbjct: 867 PE--ETAKPKDRA------TNSK--ATTPKPQKPTKAPKKPTSTKKPKTM 906
Score = 38.5 bits (88), Expect = 0.049
Identities = 80/454 (17%), Positives = 140/454 (30%), Gaps = 34/454 (7%)
Query: 1047 SRISDGKK---QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSA 1103
+ + D KK ++ P + + A L KV S Q T P
Sbjct: 64 AEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP 123
Query: 1104 VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE--EDGE 1161
+ P+ P S + + ++ + + T ++S D ++ + S+ ++ E
Sbjct: 124 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 183
Query: 1162 GPQGAKSAHTLG-PTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1220
A ++ L PTP T E P + + P TP +++
Sbjct: 184 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAP 241
Query: 1221 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1280
TPK + + S +P +P T KE A TT PK+
Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 1281 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE----RKKVVDTTKE 1336
A +P P + + K T +E K+ TT +
Sbjct: 302 APTTPK---------------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346
Query: 1337 SSRKGWESRKRKLSGDQPAARTPR----SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKR 1392
+ + +PA TP+ + K+ A + + TT+K A
Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406
Query: 1393 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1452
S K+ + + A P+E T + + PK +
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT---TPKKPAPTTPKEPAPTTPKEPAPTTT 463
Query: 1453 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1486
+K + A T E+ KK T E+
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 497
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 114 bits (286), Expect = 5e-25
Identities = 172/875 (19%), Positives = 301/875 (34%), Gaps = 121/875 (13%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
+QTS G+++ +KT D TS+ + +AET P L +
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT- 258
Query: 114 GADLPSSMKEKAKAE-------TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
P++ KE A T K+ T P P T K+ +P + EP+
Sbjct: 259 ----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK-- 219
T PA +P + A ++ ++ + ++ + T E P+
Sbjct: 315 TP---------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 365
Query: 220 --PAQVKASSVSTKE----SPARKAAPAPGKVGDVTPQVKGGALP--PAKRAKKPEEESE 271
P K + +TKE +P A AP K TP+ P PA K +
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425
Query: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVAS 328
E + + AP T+ + K A + P + +P PAP A
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 481
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR--KGA 386
+ P+E + ++ +E + + + PA + + T + A + P K +P +
Sbjct: 482 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPEKL 539
Query: 387 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
AP P K P + A E+ ++ E + A A + K P PA +
Sbjct: 540 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 599
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE----------ALAAMNAAQ 496
P++ AP P++T P + ++ ++ + + +E + A
Sbjct: 600 PKE-PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658
Query: 497 VKPLGKSPQV--KPASTMGMGPLG---KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
P G +P +PA T P KG P + P TP K E ++
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGP 717
Query: 552 SSDSSDGEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
+S +SD PT AP K KP + + PP V+ ++P
Sbjct: 718 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 777
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
+S +ES+ +E P A+ + +P + +T A K TT + K
Sbjct: 778 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA--------------K 823
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T ++P + ++++++ E +E ++ A +
Sbjct: 824 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-------------------KITATT 864
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V + Q T P T K + + ++ E + E A P
Sbjct: 865 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD-------- 916
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
RA ++K T P K A + K P VR P+ + + +++P
Sbjct: 917 ---------RATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 967
Query: 849 SV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 880
+ + Q T P + S E + + E
Sbjct: 968 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1002
Score = 109 bits (273), Expect = 2e-23
Identities = 174/883 (19%), Positives = 294/883 (33%), Gaps = 97/883 (10%)
Query: 336 EEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGAASAPAKESPRKGAA--- 387
+E + ++ + S+D +E+T +AK AK TS+V A P E+ KG A
Sbjct: 194 KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 253
Query: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
P P T P + K + S + +E AP K + P+ A + + +P
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 313
Query: 448 RKGAAPAPPRKTGPAAAQVQ----VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKS 503
PAP PA + K+ + + +E K
Sbjct: 314 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 373
Query: 504 P---QVKPASTMGMGP---LGKGAGPVPPGKVGPATPSAQV-GKWEEDSESSSEESSDSS 556
P +PA T P K P P + P TP +E S ++ +E + ++
Sbjct: 374 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433
Query: 557 DGEVPTAV---APAQEKSLGNI-LQAKPTSS--PAKGPPQKAGPVAVQVKAEKPMDNSES 610
PT AP KS + PT++ PA P++ P + A
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493
Query: 611 SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR--- 667
+ + + + PA T + P PKK T K+AP AP
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553
Query: 668 -------KAGTATSPAGSSP----AVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
+ T T+P +P A A T + ++ E + + ++ A
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613
Query: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
+ KG P AP P K P K+ S + ++ + +
Sbjct: 614 TTPKGTAPTTLKEP---------APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664
Query: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
+P K T + P + +A T+ P K+ +P+ K P +
Sbjct: 665 APTTPKEPAPTTPKEPAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723
Query: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI 896
+ P+ K A + P + E + E T K H+
Sbjct: 724 KPAPTTPKETAPTTPKEPAPTTPKKPAPT----TPETPPPTTSEVSTPTTTKEPTTIHK- 778
Query: 897 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 956
+P + +P A PTP + E S + P T A K
Sbjct: 779 ----SPDESTPELSAEPTP------------------KALENSPKEPGVPTTKTPA-ATK 815
Query: 957 PPLIFVDPNRSPAGPAATPAQAQAAS---TPRKARASESTARSSSSESEDEDVIPATQCL 1013
P + +++ T + A+ T A +E T S + + + TQ
Sbjct: 816 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDT 875
Query: 1014 TPGIRTNVVTMPTAHPRIAPKASMA--GASSSKESSRISDGKKQEGPATQVSKKNPASLP 1071
TP + T+ T +APK + ++++ ++ + K + AT P
Sbjct: 876 TP---FKITTLKTT--TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 930
Query: 1072 LTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLP 1131
T+A K + K + P V + + + T+P +P S +A R + P
Sbjct: 931 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 990
Query: 1132 EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGP 1174
+K E + SED+ + +GE P H P
Sbjct: 991 N----SKLVEVNPKSEDAGGA------EGETPHMLLRPHVFMP 1023
Score = 105 bits (262), Expect = 3e-22
Identities = 192/1023 (18%), Positives = 354/1023 (34%), Gaps = 115/1023 (11%)
Query: 66 EEDAALQAKKTRVSDP-ISTSESSEEEEEAEAETAKA-TPRLASTNSSVLGADLPSSMKE 123
E + L +V+ P ST++ ++ + TAK PR + +S + ++ +
Sbjct: 128 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 187
Query: 124 KAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFG 183
+ ET++ T N + ++ + T + +T + P
Sbjct: 188 ETTVETKET--------------TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233
Query: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
AKP + + T T + S P + +++ + + ++ AP
Sbjct: 234 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 293
Query: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
K TP+ P K+P + + ++E AP T+S ++
Sbjct: 294 KSAPTTPKE-----PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE------- 341
Query: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK 363
PA TP K A P A + P+E + ++ E + + +E PA A K
Sbjct: 342 --PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTA--PKK 396
Query: 364 ASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421
+ T + A + P + +P P+P P + P K+ +E + ++++ + +
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
Query: 422 EAPAQA---KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
+ P+ +P+ P+ A + P K +P PAP PA +
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----------- 505
Query: 479 SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQV 538
KP +P+ +PA T K P P K+ P TP
Sbjct: 506 -------------------KPAPTTPK-EPAPT-----TPKETAPTTPKKLTPTTPEKLA 540
Query: 539 GKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSPAKGPPQKAGPVAV 597
E ++ E + E PT P + A T PA P++ P
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 657
+ A + + + + + PA T + P P T P T A
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660
Query: 658 PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA--EDSSSSEESDSEEEKTGLAVTVGQA 715
P P K T+P +P GT E + ++ + + +E A
Sbjct: 661 PKGTAPTTP-KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---------LA 710
Query: 716 KSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 775
+ KG + P + + TAP P + PT + A + + + SE +
Sbjct: 711 PTTTKGPTSTTSDKPAP-TTPKETAPTTPKEPAPTTPKKPA---PTTPETPPPTTSEVST 766
Query: 776 ASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQ 835
+ + T++ K+ ++ P + P+ K ++P + ++P+ KP +
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE----PGVPTTKTPAATKPEMTTTA 822
Query: 836 NSTVLARGPASVPSVGKAV-ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH 894
R + P A + T E+ + S + ++ + T P T
Sbjct: 823 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 882
Query: 895 QIRAALAPAKESPRKGAAPTP-PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
LAP + +K T K +A + +S +++ + +AP TS +
Sbjct: 883 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 942
Query: 954 VIKPPLIFVDPNRSPA-----------GPAATPAQAQAASTPRKARASESTARSSSSESE 1002
K P +P P + A+A +T R + S + +SE
Sbjct: 943 KPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1002
Query: 1003 D----EDVIPATQCLTPGIRTNVVTMPTAH-PRIAPKASMAGASSSKESSRISDGKKQEG 1057
D E P L P + VT + PR+ + + S E++ I +GK +G
Sbjct: 1003 DAGGAEGETP-HMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETN-ICNGKPVDG 1060
Query: 1058 PAT 1060
T
Sbjct: 1061 LTT 1063
Score = 87.4 bits (215), Expect = 9e-17
Identities = 193/950 (20%), Positives = 317/950 (33%), Gaps = 153/950 (16%)
Query: 414 SEESDSEEEAPAQAKPSGKA-PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
S E E + AQ K K P + A K++ +K P P + G
Sbjct: 77 SFERGRECDCDAQCKKYDKCCPDYESFCAEVKDN-KKNRTKKKPTPKPPVVDEAGSGLDN 135
Query: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532
D + ++ ++ + Q + SP++ A + P +PP
Sbjct: 136 GDFKVTTPDTST----------TQHNKVSTSPKITTAKPINPRP------SLPPNSDTSK 179
Query: 533 TPSAQVGKWE--EDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
S V K E E+++ S+DG E T+ Q + PTS P
Sbjct: 180 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 239
Query: 590 QKA-----GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK-- 642
KA GP K P + +E + + E P + +A P P T
Sbjct: 240 PKAETTTKGPALTTPKEPTPT----TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 643 --ACPKKTNTTASAKVAPVRVGTQAP----RKAGTATSPAGSSPAVAGGT--QRPAEDSS 694
PK+ T + + AP AP A T T A ++P T ++PA +
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 695 SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
+ +E T K + A + P + + TAP P T P
Sbjct: 356 KEPAPTTPKEPTPTT-----PKEPAPTTKEPAPTTPKEPA---PTAPKKPAPTTPKEPAP 407
Query: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
K+ +++E S + +P K++ T+ PA SA T P T
Sbjct: 408 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK---EPAPTTTKSAPTTPKEPSPTTT 464
Query: 815 AAAQAKQRSPSKVKPPV----RNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS 870
K+ +P+ K P + P +T P + P T A T P+E + +
Sbjct: 465 -----KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPAPTTTKKPAPTTPKEPAPT 518
Query: 871 SEEESD-------SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSA 923
+ +E+ + E LA P LAP P P T P A
Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 578
Query: 924 AQAG--KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAA 981
A K+ + E + + + PA T + +P G A T + A
Sbjct: 579 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT---------TPKGTAPTTLKEPAP 629
Query: 982 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 1041
+TP+K E ++ + +T C P T T PT AP A
Sbjct: 630 TTPKKPAPKELAPTTTKEPT-------STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 682
Query: 1042 SSKESSRISDGKKQ------------------EGPATQVSKKNPASLPLTQAAL------ 1077
++ + + + K+ +GP + S K + P A
Sbjct: 683 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742
Query: 1078 ------------KVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL 1125
+ SE P +P++ S + P S + T + N
Sbjct: 743 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE--NSP 800
Query: 1126 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEE 1185
++P +P TK P ++ ++ +E D T T + + +E
Sbjct: 801 KEPGVP----TTKTPAATKPEMTTTAKDKTTERD---------LRTTPETTTAAPKMTKE 847
Query: 1186 TA--AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKAT---PKLDSSPSVSSTLAAKDD 1240
TA E + + + + + ++ T TP K T PK+ ++ +T +
Sbjct: 848 TATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK 907
Query: 1241 PDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK-PKKGAGNPQASTL 1289
P+ + AKP+ A T K A+ PQK K PKK + T+
Sbjct: 908 PE--ETAKPKDRA------TNSK--ATTPKPQKPTKAPKKPTSTKKPKTM 947
Score = 38.5 bits (88), Expect = 0.049
Identities = 80/454 (17%), Positives = 140/454 (30%), Gaps = 34/454 (7%)
Query: 1047 SRISDGKK---QEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSA 1103
+ + D KK ++ P + + A L KV S Q T P
Sbjct: 105 AEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP 164
Query: 1104 VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE--EDGE 1161
+ P+ P S + + ++ + + T ++S D ++ + S+ ++ E
Sbjct: 165 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 224
Query: 1162 GPQGAKSAHTLG-PTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1220
A ++ L PTP T E P + + P TP +++
Sbjct: 225 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAP 282
Query: 1221 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1280
TPK + + S +P +P T KE A TT PK+
Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 1281 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE----RKKVVDTTKE 1336
A +P P + + K T +E K+ TT +
Sbjct: 343 APTTPK---------------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387
Query: 1337 SSRKGWESRKRKLSGDQPAARTPR----SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKR 1392
+ + +PA TP+ + K+ A + + TT+K A
Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447
Query: 1393 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1452
S K+ + + A P+E T + + PK +
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT---TPKKPAPTTPKEPAPTTPKEPAPTTT 504
Query: 1453 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1486
+K + A T E+ KK T E+
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 538
>gi|112821681 G protein-regulated inducer of neurite outgrowth 1 [Homo
sapiens]
Length = 1008
Score = 109 bits (273), Expect = 2e-23
Identities = 220/996 (22%), Positives = 357/996 (35%), Gaps = 165/996 (16%)
Query: 234 PARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
P P G +G + ++ K + P + G ES +P+G
Sbjct: 24 PTAFFCPQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASC 83
Query: 294 SEKILQVRAASAPA----KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDS 349
S+ A +P + +P K A T +GKPE S +E S S
Sbjct: 84 SDGPRGSLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKS-S 142
Query: 350 EEETPAAKALLQAKASGKTSQVGAASAPAKESP---RKG---------------AAPAPP 391
++ P + K K+S+ +++ KE P RK P P
Sbjct: 143 DDRNP----MFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAP 198
Query: 392 GKTGPAVAKAQ----AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA-PAKES 446
G+ P + + GK + S + +E P + + P KE
Sbjct: 199 GRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEE 258
Query: 447 PRKGAA--PAPPRKTGPAAAQ----VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
PR P K P +A+ V GK+ D S + E++ + + + +P
Sbjct: 259 PRYSGKEHPVSSEKVAPTSAEKVDLVLSGKR--DPGPSGKADPMPLESMDSASTGKTEP- 315
Query: 501 GKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS-------AQVGKWE------EDSE- 546
G ++ P S+ GP+ G G PG +G P+ A VG E EDS
Sbjct: 316 GLLGKLIPGSSGKNGPVSSGTGA--PGSLGRLDPTCLGMADPASVGNVETVPATKEDSRF 373
Query: 547 ------SSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
+SS E S TA A SL N+ P SS K P G +
Sbjct: 374 LGKMDPASSGEGRPVSGHTDTTASAKTDLTSLKNV---DPMSS-GKVDPVSLGKMDPMCS 429
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAM--TAAQAKPALKIPQTKACPKKTNTTASAKVAP 658
+ + + +E S +P +++ + + K +K N +S K P
Sbjct: 430 GKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNP 489
Query: 659 VRVGTQAPRKAGTATSP-------------------------AGSSPAVAGGTQRP---- 689
V G PR GTA P +G + A G P
Sbjct: 490 VSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVG 549
Query: 690 AEDSSSSEESDSEEEKTGLAVTVGQAKSV-GKGLQVKAASV-PVK----GSLGQGTAPVL 743
ED S ++D+ G +V++G+ S GK + V + V PV ++ +G L
Sbjct: 550 KEDPVSKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSL 609
Query: 744 PGKTGPTVTQVKAEKQEDSES-------SEEESDSEEAAASPAQ-----VKTSVKKTQAK 791
P + G VT KA+ + ++ +E + +E AA+P + +K + K
Sbjct: 610 PLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEK 669
Query: 792 ANPAAAR----APSAKGTISAPGKVVTAAAQAKQRSPS--KVKPPVRNPQNSTVLARGPA 845
+P + R S KG + GK +A ++ K SPS KV P S + +
Sbjct: 670 VDPGSCRKAEPLASGKGEPVSLGKADSAPSR-KTESPSLGKVVP------LSLEKTKPSS 722
Query: 846 SVPSVGKAVATAAQAQTGPEEDSGSSEEESD--SEEEAETLAQVKPSGKTHQIRAALAPA 903
S + + +A++ G G E +++ S EA +L Q + AA A
Sbjct: 723 SSRQLDRKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQ-------KDLEAAGAER 775
Query: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
P + AAP P +T + +A + S D+ +A A + + P +
Sbjct: 776 SPCP-EAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSP----MS 830
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 1023
P G A + A A +P R + ++E T+ + G T
Sbjct: 831 PQDGAGGSAFSFQAAPRAPSPPSRRDAGLQVSLGAAE---------TRSVATGPMTPQAA 881
Query: 1024 MPTAHP--RIAPKASMAGASSSKESSR-ISDGKKQE--------GPATQVSKKNPASLPL 1072
P A P R+ P +++A A + E + + D E G A +V A
Sbjct: 882 APPAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAIQKH 941
Query: 1073 TQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLP 1108
+ ++ ++ + A PP AR P G +V T P
Sbjct: 942 LERQIEEHGRQGAPAPPPAARAGP--GRSGSVRTAP 975
Score = 44.3 bits (103), Expect = 9e-04
Identities = 90/409 (22%), Positives = 143/409 (34%), Gaps = 79/409 (19%)
Query: 91 EEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVAN 150
E+ + T KA PR + G P S KAET+ G+ G + P G+ A
Sbjct: 612 EKGSPVTTTKADPRAS-------GKAQPQS---GGKAETKLPGQEGAAAP----GEAGAV 657
Query: 151 LLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS------------ 198
L ++P+ S + + +E G K VS G+ADS
Sbjct: 658 CLKKETPQASEKVDPGSCRKAEPLASG---------KGEPVSLGKADSAPSRKTESPSLG 708
Query: 199 -----SSEDTSSSSDETDVEGKP------------SVKPAQVKASSVSTKESPARKAAPA 241
S E T SS ++ K S + KA VS+ E+ +
Sbjct: 709 KVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDL 768
Query: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVR 301
+ +P + A PP R + ++ S E + AGT++ +A V
Sbjct: 769 EAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQAC-----VS 823
Query: 302 AASAPAKGTPGKGAT----------PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEE 351
A +P G G + P+PP + A Q G +E+ S +
Sbjct: 824 VAVSPMSPQDGAGGSAFSFQAAPRAPSPPSRRDA-GLQVSLGA----AETRSVATGPMTP 878
Query: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKT----GPAVAKAQAGKRE 407
+ A A + + ++ A + P P + + G T G A+ G
Sbjct: 879 QAAAPPAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAI 938
Query: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
+ E + APA P+ +A R+ S + +P GAA PP
Sbjct: 939 QKHLERQIEEHGRQGAPA-PPPAARAGPGRSGS--VRTAPPDGAAKRPP 984
Score = 35.8 bits (81), Expect = 0.32
Identities = 110/529 (20%), Positives = 177/529 (33%), Gaps = 93/529 (17%)
Query: 967 SPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPT 1026
SPA P TP Q+ + ++ + S S P+ C +P + T+
Sbjct: 53 SPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSKETLEA 112
Query: 1027 AHPRIA--PKASMAG----ASSSKESSRISDGKK------------QEGPATQVSKKNPA 1068
I+ P+A+ +G SS K + SD + ++ +T + K++P
Sbjct: 113 HGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPG 172
Query: 1069 SLPLTQAALKVLAQKASEAQP-------PVA--RTQPSSGVDSAVGTLPATSPQSTSVQA 1119
S + K +A+P PVA R P + +G+L P +S
Sbjct: 173 S------SRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSS--- 223
Query: 1120 KGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRT 1179
P+ + K S D D E G + S+ + PT +
Sbjct: 224 --KTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRK-EEPRYSGKEHPVSSEKVAPTSAEK 280
Query: 1180 ETLV-------------EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLD 1226
LV + ES + ++ L G + PG + N S T
Sbjct: 281 VDLVLSGKRDPGPSGKADPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPG 340
Query: 1227 SSPSVSSTLAAKDDPD--GKQEAKP-----QQAAGMLSPKTGGK---------EAASGTT 1270
S + T DP G E P + G + P + G+ AS T
Sbjct: 341 SLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASAKT 400
Query: 1271 PQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQ-ASVVKVLT------ELL 1323
S K + + ++L C G+P L+ Q + SV K T + +
Sbjct: 401 DLTSLKNVDPMSSGKVDPVSLGKMDPMCS-GKPELLSPGQAERVSVGKAGTVSPGKEDPV 459
Query: 1324 EQERKKVVD--TTKESSRKGWESRKRKLS------GDQPAART---PRSKKKKKLGAGEG 1372
R+ + + K SS K K + GD + T P + K + G+G
Sbjct: 460 SSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKG 519
Query: 1373 GEAS------VSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKD 1415
S V+ K + T+ GKA+ + KGK G G D
Sbjct: 520 DPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQGD 568
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 108 bits (271), Expect = 3e-23
Identities = 289/1408 (20%), Positives = 460/1408 (32%), Gaps = 198/1408 (14%)
Query: 76 TRVSDPISTSESSEEEEEAEAE--TAKATPRLASTNSSVLGADLPSSMKEKAKAETE--- 130
T D +TS+ S+E + + + +AT ST +S LG + ET
Sbjct: 1481 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1540
Query: 131 ----KAGKTGNSMP-HPATGKTVANLLSGKSPRKSAEPSANT--TLVSETEEEGSVPAFG 183
+G S P H +TG L S + + T + S ++ S P
Sbjct: 1541 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTT 1600
Query: 184 AA---------AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSV---------------- 218
AA ++P +SS S + T V P
Sbjct: 1601 AAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLV 1660
Query: 219 -KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGS 277
+P SS ST+ + + G T P + S SEE +
Sbjct: 1661 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 1720
Query: 278 ESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE 337
S + + S + V S + +PG T PG A + PE
Sbjct: 1721 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG-----PES 1775
Query: 338 DSESSSEESSDSE--EETPAAKALLQAKA---------------SGKTSQVGAASAPAKE 380
+ SS S+++ + A LL+A +G T++ G ++
Sbjct: 1776 TTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1835
Query: 381 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ-------SSSEESDSEEEAPAQAKPSGKA 433
K PAPP T V + S SS+ SEE + P A
Sbjct: 1836 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 1895
Query: 434 PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMN 493
+PA+ + + + P + Q + + SEES + + +
Sbjct: 1896 ----TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT--H 1949
Query: 494 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 553
P S V+ ++ P P S G+ EE + S S + +
Sbjct: 1950 TISSPPSTTSALVEEPTSYHSSPGSTATTHFPDS-------STTSGRSEESTASHSSQDA 2002
Query: 554 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 613
T V PA +S ++L + T+SP + + + S +
Sbjct: 2003 TG------TIVLPA--RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 2054
Query: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
S S + +PA+ T++ ++ P T+TTA T P + +T
Sbjct: 2055 SPRSPATTLSPASTTSSGVSEESTTSHSR--PGSTHTTAFPD------STTTPGLSRHST 2106
Query: 674 SPAGSSPAVAGGTQRPAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
+ + SSP T PA ++S S S S T A++ G ++ G +
Sbjct: 2107 T-SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE----- 2160
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
T PG T T+ + + S + +V +S
Sbjct: 2161 --------STTFHSSPGSTHTTLFP-------------DSTTSSGIVEASTRVHSSTGSP 2199
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
+ +PA++ +P +G +A + A+ PS PV + ST R P S P
Sbjct: 2200 RTTLSPASSTSPGLQGESTA-FQTHPASTHTTPSPPSTATAPV---EESTTYHRSPGSTP 2255
Query: 849 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPR 908
+ A+ +G E S D+ + A SG+ + ++P
Sbjct: 2256 TTH---FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE-- 2310
Query: 909 KGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 968
P T P ++A + SS S + +PA++TS V + + S
Sbjct: 2311 --ITTLPGSTTTPGLSEAST---TFYSSPRSPTTTLSPASMTSLGVGE------ESTTSR 2359
Query: 969 AGPAATPAQAQAASTPRKARASESTA-RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 1027
+ P +T + AST + EST SSS S + V P T T +R T T
Sbjct: 2360 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTP--TTSVRGEEPT--TF 2415
Query: 1028 HPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEA 1087
H R A + S S + G PA+L + +S
Sbjct: 2416 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 2475
Query: 1088 QPPVARTQPSSGVDSAVG---------------TLPATSPQSTSVQAKGTNKLRKPKLPE 1132
+ S VG TLP SP + S+ K T P+ P+
Sbjct: 2476 STGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPG-SPTTPSLSEKSTTFYTSPRSPD 2534
Query: 1133 VQQATKAPESSDDSEDSSDSSS--GSEEDGEGPQG------AKSAHTLGPTPSRTETLV- 1183
+ SS SE+SS S S GS P ++ + T +P T+T +
Sbjct: 2535 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 2594
Query: 1184 ---EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1240
T+ S E S ++PG T A S ++T S S +TL
Sbjct: 2595 PASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF---- 2650
Query: 1241 PDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLL 1300
PD + +A+ + TG +P S P + T ++ T
Sbjct: 2651 PDSTTSSGIVEASTRVHSSTGSPRTT--LSPASSTSPGLQGESTTFQTHPASTHTT---- 2704
Query: 1301 GQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR--T 1358
P P + A + V+ T SS S K + P A T
Sbjct: 2705 --PSPPSTA---TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 2759
Query: 1359 PRSKKKKKLGAGEGGEASVSPEKTSTTS 1386
P S G GE + +SP T T+
Sbjct: 2760 PSSAHSTTSGRGESTTSRISPGSTEITT 2787
Score = 102 bits (255), Expect = 2e-21
Identities = 278/1318 (21%), Positives = 451/1318 (34%), Gaps = 205/1318 (15%)
Query: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL- 113
+T+ G K+ + ++ P ST+ +E + + ST++++
Sbjct: 298 RTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG-----STDTTLSP 352
Query: 114 GADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLV--S 171
G PSS+ ++ G T + T T + LL +P S+ S +TTL S
Sbjct: 353 GTTTPSSLGPESTTFHSSPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPSS 410
Query: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
T EG F + S + ++S S T PS P S+ ST
Sbjct: 411 STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLS---TTYHSSPSSTPT-THFSASSTT 466
Query: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS---EEGSESEEEAPAGTR 288
+ ++ P +P PPA+ A E ++ GS P +
Sbjct: 467 LGHSEESTPVHS-----SPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST 521
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
+ + E + + TP A A ++ S + + S E S
Sbjct: 522 TSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESK 581
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK-TGPAVAKAQ----A 403
+ +P A A A S + S P+ S A PG T P +++ +
Sbjct: 582 ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYS 641
Query: 404 GKREEDS----QSSSEESDSEEEAPAQAKPSG----KAPQVRAASAPAKESPRKGAAPAP 455
R D+ S + SEE + ++P P ++ES ++P P
Sbjct: 642 SPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 701
Query: 456 PRKT----GPAAAQVQVGKQEEDSRSSSEES---DSDREALAAMNAAQ------------ 496
T A+ + SR S E+ + A + A+
Sbjct: 702 TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTT 761
Query: 497 VKPLGKSPQVKPASTMGMGPLGKGAGPVPP----GKVGPATPS----AQVGKWEEDSESS 548
+ P G + + ++T P K P PP V P+T S + + + S+
Sbjct: 762 LSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARST 821
Query: 549 S----EESS--DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE 602
+ EES+ SS G T P + + G + TS + + P E
Sbjct: 822 TSGLVEESTTYHSSPGSTQTMHFPESDTTSGR-GEESTTSHSSTTHTISSAPSTTSALVE 880
Query: 603 KPMDNSES---------SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS 653
+P S + S+ S SEE+ A+ ++ A + +P + +
Sbjct: 881 EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 940
Query: 654 AKVAPVRVGTQAPRKAGTATSPA--------GSSPAVAGGTQRPAEDSSS--SEESDSEE 703
+ ++ + T A G+ T+P SSP T PA +SS SEES +
Sbjct: 941 SPISSGSMETTA--LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSR 998
Query: 704 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 763
+ G T S + S S G +LP T + ++S
Sbjct: 999 SRPGSTHTTAFPDSTTTP-GLSRHSTTSHSSPGSTDTTLLPAST------TTSGPSQEST 1051
Query: 764 SSEEESDSEEAAASP----------------------------------------AQVKT 783
+S S S + A SP +V +
Sbjct: 1052 TSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHS 1111
Query: 784 SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARG 843
S + +PA++ +P +G S + A+ PS PV + ST R
Sbjct: 1112 STGSPRTTLSPASSTSPGLQGE-STAFQTHPASTHTTPSPPSTATAPV---EESTTYHRS 1167
Query: 844 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPA 903
P S P+ A+ +G E S D+ + A SG+ + ++P
Sbjct: 1168 PGSTPTTH---FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 1224
Query: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
P T P ++A + SS S + +PA++TS V + +
Sbjct: 1225 STE----ITTLPGSTTTPGLSEA---STTFYSSPRSPTTTLSPASMTSLGVGE------E 1271
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 1023
S + P +T + AST + EST SSS E + T + T
Sbjct: 1272 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV-FPHSTTTSVHGEEPT 1330
Query: 1024 MPTAHPRIA--------PKASMAGASSSKESSRISDGKKQEG-PAT-------QVSKKNP 1067
T H R A ++ +G + + S Q G PAT + S P
Sbjct: 1331 --TFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFP 1388
Query: 1068 ASLPLTQAALKVLAQKAS----EAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTN 1123
+S T L S E+ P +R PSS + TLP SP + S+ K T
Sbjct: 1389 SSSGSTGTKLSPARSTTSGLVGESTP--SRLSPSS---TETTTLPG-SPTTPSLSEKSTT 1442
Query: 1124 KLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLG-PTPSRTETL 1182
P+ P+ AT +P ++ S S +SS+ + G S HT P + T L
Sbjct: 1443 FYTSPRSPD---ATLSPATTTSSGVSEESSTSHSQPG-------STHTTAFPDSTTTSDL 1492
Query: 1183 VEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1240
+E S SQ ++PG T A+S ++T SSP + T DD
Sbjct: 1493 SQEPTTSHS-------SQGSTEATLSPGSTTASSLGQQST-TFHSSPGDTETTLLPDD 1542
Score = 102 bits (254), Expect = 3e-21
Identities = 282/1399 (20%), Positives = 487/1399 (34%), Gaps = 163/1399 (11%)
Query: 98 TAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSP 157
T ++PR +T S + S + E++ + G T + +T T L +
Sbjct: 968 TFHSSPRSPATTLSP-ASTTSSGVSEESTTSRSRPGSTHTTAFPDST--TTPGLSRHSTT 1024
Query: 158 RKSAEPSANTTLV-----------SETEEEGSVPAFGAAAKPGMVSA---GQADSSSEDT 203
S+ S +TTL+ T S + A PG +A GQ +S++ +
Sbjct: 1025 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQ-ESTTFHS 1083
Query: 204 SSSSDETDVEGKPSVKPAQVKASSV--STKESPARKAAPA----PGKVGDVT-----PQV 252
+ S T + + V+AS+ S+ SP +PA PG G+ T P
Sbjct: 1084 NPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 1143
Query: 253 KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312
P A P EES + S S + + +S A GT
Sbjct: 1144 THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP 1203
Query: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSS------EESSDSEEETPAAKALLQAKASG 366
A G+ + S+ G E + S E+S + +P + + AS
Sbjct: 1204 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 1263
Query: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEES--------- 417
+ VG S ++ P + P T ++ S+ S+E +
Sbjct: 1264 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTS 1323
Query: 418 -DSEEEAPAQAKPSGKAPQV----RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
EE ++P+ + S +ES +PA + PA +E
Sbjct: 1324 VHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 1383
Query: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK---- 528
+ SS S + + A + + ++ P+ST G P K
Sbjct: 1384 STTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF 1443
Query: 529 -VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG 587
P +P A + S SEESS S T + + + L +PT+S +
Sbjct: 1444 YTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQ 1503
Query: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA-AMTAAQAKPALKIPQTKACPK 646
+A A S + S ++ P +T+ + + +
Sbjct: 1504 GSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLH 1563
Query: 647 KTNTTASAKVAPVRVGTQA----PRKAGTATSPAGSSPAVAGGT----QRPAED-----S 693
T T AS+ A ++ + P + T SP G++ A + RP+ S
Sbjct: 1564 TTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFS 1623
Query: 694 SSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKGSLGQGTAPVLPGKT----- 747
+SS EE T + + G + G L ++A+ + G T+P+ G T
Sbjct: 1624 ASSTTLGRSEESTTVHSSPG---ATGTALFPTRSATSVLVGE--PTTSPISSGSTETTAL 1678
Query: 748 -GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
G T T +EK SS D+ + AS S + T + + P + + G+
Sbjct: 1679 PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGST 1738
Query: 807 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP---SVGKAVATAA----- 858
+ PG V+ + A SP + +P ++T + GP S S G T
Sbjct: 1739 TMPG--VSQESTASHSSPGSTDTTL-SPGSTTASSLGPESTTFHSSPGSTETTLLPDNTT 1795
Query: 859 -----QAQTGPEEDSGS-----SEEESDSEEEAETLAQVKPSGKTHQ-----IRAALAPA 903
+A T +GS S S + + T Q PS K +A
Sbjct: 1796 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVEL 1855
Query: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGS--SSEESDSDGEAPAAVTSAQVIKPPLIF 961
+ + TP S+ G+ ++S + SS + + +PA T++ +++ +
Sbjct: 1856 STTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAY 1915
Query: 962 VDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 1021
++P Q P + AS + S +S S I + P + +
Sbjct: 1916 ----------HSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP----PSTTSAL 1961
Query: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLA 1081
V PT++ +P ++ A++ S + G+ +E A+ S+ ++ L + +
Sbjct: 1962 VEEPTSY-HSSPGST---ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL 2017
Query: 1082 QKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPE 1141
S P + + ++ + + T P S +ST+ + P+ P + +
Sbjct: 2018 LGESTTSPISSGSMETTALPGST-TTPGLSEKSTTFHSS-------PRSPATTLSPASTT 2069
Query: 1142 SSDDSEDSSDSSS--GSEEDGEGPQG------AKSAHTLGPTPSRTETLV----EETAAE 1189
SS SE+S+ S S GS P ++ + T +P T+T + T+
Sbjct: 2070 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 2129
Query: 1190 SSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKP 1249
S E S ++PG T A S ++T S S +TL PD +
Sbjct: 2130 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF----PDSTTSSGI 2185
Query: 1250 QQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEA 1309
+A+ + TG +P S P + T ++ T P P + A
Sbjct: 2186 VEASTRVHSSTGSPRTT--LSPASSTSPGLQGESTAFQTHPASTHTT------PSPPSTA 2237
Query: 1310 QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR--TPRSKKKKKL 1367
+ V+ T SS S K + P A TP S
Sbjct: 2238 ---TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS 2294
Query: 1368 GAGEGGEASVSPEKTSTTS 1386
G GE + +SP T T+
Sbjct: 2295 GRGESTTSRISPGSTEITT 2313
Score = 101 bits (251), Expect = 6e-21
Identities = 247/1228 (20%), Positives = 421/1228 (34%), Gaps = 162/1228 (13%)
Query: 81 PISTSESSEEEEEAEAETAKATPR--LASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
P ST+ S E ++ +PR L+ +S+ G S+ + A T ++
Sbjct: 3734 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 3793
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE--TEEEGSVPAFGAAAKPG-MVSAGQ 195
P T + G +P S+ T+ SE T S A G ++G+
Sbjct: 3794 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 3853
Query: 196 ADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV--STKESPARKAAPAPGK---VGD--V 248
+S++ S S E + P +AS+ S+ SP +PA VG+
Sbjct: 3854 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 3913
Query: 249 TPQVKGGAL-----PPAKRAKKPEEESE---SSEEGSESEEEAPAGTRSQVKASEKI-LQ 299
T + + G+ P + EES SS GS P T + V+ E
Sbjct: 3914 TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFH 3973
Query: 300 VRAASAPA----KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
R AS + + G T G+ AS T+ G P + + E S + +
Sbjct: 3974 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS-TQTGLPATLTTADLGEESTTFPSSSG 4032
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
+ + A TS + S P++ SP PG + S SE
Sbjct: 4033 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP--------------TTPSLSE 4078
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
+S + +P ++ + +P +S ++ES + P T + G +E +
Sbjct: 4079 KSTTFYTSP-RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPT 4137
Query: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS 535
S S + + EA + + LG+ +S + G V +TP+
Sbjct: 4138 TSHSSQGST--EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 4195
Query: 536 AQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLG-----NILQAKPTSSPAKGPPQ 590
SS G + T + PA S G Q+ P+SS P
Sbjct: 4196 ------------------HSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPP 4237
Query: 591 KAGPVAVQVKA---EKPMDNSES--SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
V V+V +P + S S+ SEE+ ++ A P A
Sbjct: 4238 STTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT- 4296
Query: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAG---------SSPAVAGGTQRPAEDSSS- 695
+ +P+ G+ +T+ AG SSP T PA +SS
Sbjct: 4297 --SVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG 4354
Query: 696 -SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
SEES + + G T S V S S G + PG T +
Sbjct: 4355 VSEESTTSHSRPGSMHTTAFPSSTTMP-GVSQESTASHSSPGSTDTTLSPGSTTASSLGP 4413
Query: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
++ S S E + + + ++ S + +P +P+ T
Sbjct: 4414 ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 4473
Query: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
+ +K +P+ + ST P+S P+ + ++ ++ EE
Sbjct: 4474 SWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS----------EE 4523
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS 934
S + + PS PA+ + + + P + Q +S +
Sbjct: 4524 STTVHSSPVATATTPS-----------PARSTTSGLVEESTTYHSSPGSTQTMHFPESNT 4572
Query: 935 SS---EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASE 991
+S EES + + S+ + +P + P +T S+ R+ E
Sbjct: 4573 TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 4632
Query: 992 STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD 1051
STA SS ++ V+PA + ++ +P +S + +++ S +
Sbjct: 4633 STASHSSQDATGTIVLPAR---------STTSVLLGESTTSPISSGSMETTALPGSTTTP 4683
Query: 1052 GKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSA-VGTLPAT 1110
G ++ S P+S P T S + + R++ S+ V S+ V T
Sbjct: 4684 GLSEKSTTFHSS---PSSTPTTHF---------SASSTTLGRSEESTTVHSSPVATATTP 4731
Query: 1111 SPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAH 1170
SP ++ P Q PESS S S +S + + + H
Sbjct: 4732 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSH---------SSTTH 4782
Query: 1171 TLGPTPSRTETLVEETAAESSEDDVVA----PSQSLLSGYM-----------TPGLTP-- 1213
T+ PS T LVEE + S +A P S SG T G+TP
Sbjct: 4783 TISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLP 4842
Query: 1214 ----ANSQASKATPKLDSSPSVSSTLAA 1237
+ + +++T S S+ +TLA+
Sbjct: 4843 AHFTTSGRIAESTTFYISPGSMETTLAS 4870
Score = 99.0 bits (245), Expect = 3e-20
Identities = 272/1299 (20%), Positives = 444/1299 (34%), Gaps = 176/1299 (13%)
Query: 81 PISTSESSEEEEEAEAETAKATPR--LASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
P ST+ S E ++ +PR L+ +S+ G S+ + A T ++
Sbjct: 1094 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 1153
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE--TEEEGSVPAFGAAAKPG-MVSAGQ 195
P T + G +P S+ T+ SE T S A G ++G+
Sbjct: 1154 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 1213
Query: 196 ADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV--STKESPARKAAPAPGK---VGD--V 248
+S++ S S E + P +AS+ S+ SP +PA VG+
Sbjct: 1214 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 1273
Query: 249 TPQVKGGAL-----PPAKRAKKPEEESE---SSEEGSESEEEAPAGTRSQVKASEKI-LQ 299
T + + G+ P + EES SS GS P T + V E
Sbjct: 1274 TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFH 1333
Query: 300 VRAASAPA----KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
R AS + + G T G+ AS T+ G P + + E S + +
Sbjct: 1334 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS-TQTGLPATLTTADLGEESTTFPSSSG 1392
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
+ + A TS + S P++ SP PG + S SE
Sbjct: 1393 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP--------------TTPSLSE 1438
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
+S + +P ++ + +P +S ++ES + P T + +E +
Sbjct: 1439 KSTTFYTSP-RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPT 1497
Query: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS 535
S S + + EA + + LG+ +S + G V +TP+
Sbjct: 1498 TSHSSQGST--EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 1555
Query: 536 AQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLG-----NILQAKPTSSPAKGPPQ 590
SS G + T + PA S G Q+ P+SS P
Sbjct: 1556 ------------------HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPP 1597
Query: 591 --KAGPVAVQVKAEKPMDNSESSEESSDSAD---SEEAPAAMTAAQAKPALKIPQTKACP 645
A PV V ++ ++ S+ S SEE+ ++ A P A
Sbjct: 1598 GTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT- 1656
Query: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAG---------SSPAVAGGTQRPAEDSSS- 695
+ +P+ G+ +T+ AG SSP T PA +SS
Sbjct: 1657 --SVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG 1714
Query: 696 -SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKT------- 747
SEES + + G T S V S S G + PG T
Sbjct: 1715 VSEESTTSHSRPGSTHTTAFPGSTTMP-GVSQESTASHSSPGSTDTTLSPGSTTASSLGP 1773
Query: 748 ---------GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAAR 798
G T T + + S E + + SP + T + +
Sbjct: 1774 ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 1833
Query: 799 A-PSAKGTISAPGKVVTAAAQ---AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
+ PS+K T+ AP +A + SPS P +ST L R S V
Sbjct: 1834 SWPSSKDTMPAPPTTTSAFVELSTTSHGSPSST-PTTHFSASSTTLGRSEESTTVHSSPV 1892
Query: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914
ATA SG EE + A +
Sbjct: 1893 ATATTPSPARSTTSGLVEEST-----------------------------------AYHS 1917
Query: 915 PPGKTGP-----SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 969
PG T S+ +G+ ++S +S + +P + TSA V +P P
Sbjct: 1918 SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP----- 1972
Query: 970 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA---TQCLTPGIRTNVVTMPT 1026
G AT +++T R+ ESTA SS ++ V+PA T L T+ ++ +
Sbjct: 1973 GSTATTHFPDSSTT--SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 2030
Query: 1027 AHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASE 1086
P ++ S K ++ S + PAT +S + S +++ + ++ S
Sbjct: 2031 METTALPGSTTTPGLSEKSTTFHSSPR---SPATTLSPASTTSSGVSEESTTSHSRPGST 2087
Query: 1087 AQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD- 1145
+ + G+ S T +SP ST + E + +P S+D
Sbjct: 2088 HTTAFPDSTTTPGL-SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTA 2146
Query: 1146 -SEDSSDSSSGSEEDGEGPQGAKSAH-TLGPTPSRTETLVEET----AAESSEDDVVAPS 1199
S S+ + S +E S H TL P + + +VE + ++ S ++P+
Sbjct: 2147 LSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 2206
Query: 1200 QSL---LSGYMTPGLT-PANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA--A 1253
S L G T T PA++ + + P ++P ST + P + +
Sbjct: 2207 SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 2266
Query: 1254 GMLSPKT--GGKEAASGTTPQKSRKPKKGAGNPQASTLA 1290
G T ASGTTP + G G S ++
Sbjct: 2267 GHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 2305
Score = 98.6 bits (244), Expect = 4e-20
Identities = 285/1411 (20%), Positives = 487/1411 (34%), Gaps = 161/1411 (11%)
Query: 78 VSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGN 137
+S+ +T +S +A A T S SS + S+ T G + +
Sbjct: 2519 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRH 2578
Query: 138 SMP-HPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSA--- 193
S H + G T LL + + T+ S + A PG +A
Sbjct: 2579 STTSHSSPGSTDTTLLPASTTTSGPSQESTTS-------HSSPGSTDTALSPGSTTALSF 2631
Query: 194 GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV--STKESPARKAAPA----PGKVGD 247
GQ +S++ +S S T + + V+AS+ S+ SP +PA PG G+
Sbjct: 2632 GQ-ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE 2690
Query: 248 VT-----PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRA 302
T P P A P EES + S S + +
Sbjct: 2691 STTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH 2750
Query: 303 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSS------EESSDSEEETPAA 356
+S A GT A G+ + S+ G E + S E+S + +P +
Sbjct: 2751 SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS 2810
Query: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKT--------GPAVAKAQAGKREE 408
+ AS + VG S ++ P + P T V + G E
Sbjct: 2811 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 2870
Query: 409 D--SQSSSEESDSEEEAPAQAKPSGKAPQV----RAASAPAKESPRKGAAPAPPRKTGPA 462
+S++ EE ++P+ + S +ES +PA + PA
Sbjct: 2871 TVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 2930
Query: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP--QVKPASTMGMGPLGKG 520
+ E+S + S S L+ + +G+S ++ P+ST G
Sbjct: 2931 T--LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 2988
Query: 521 AGPVPPGK-----VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI 575
P K P +P A + S SEESS S T + + +
Sbjct: 2989 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSG 3048
Query: 576 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA-AMTAAQAKP 634
L +PT+S + +A A S + S ++ P +T+ +
Sbjct: 3049 LSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA 3108
Query: 635 ALKIPQTKACPKKTNTTASAKVAPVRVGTQA----PRKAGTATSPAGSSPAVAGGT---- 686
+ + T T AS+ A ++ + P + T SP G++ A +
Sbjct: 3109 STPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYH 3168
Query: 687 QRPAED-----SSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKGSLGQGTA 740
RP+ S+SS EE T + + G + G L ++A+ + G T+
Sbjct: 3169 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPG---ATGTALFPTRSATSVLVGE--PTTS 3223
Query: 741 PVLPGKT------GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANP 794
P+ G T G T T +EK SS D+ + AS S + T + + P
Sbjct: 3224 PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 3283
Query: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
+ + G+ + PG V+ + A SP + +P ++T + GP S
Sbjct: 3284 GSTHTTAFPGSTTMPG--VSQESTASHSSPGSTDTTL-SPGSTTASSLGPESTTFHSGPG 3340
Query: 855 ATAA-------------QAQTGPEEDSGS-----SEEESDSEEEAETLAQVKPSGKTHQ- 895
+T +A T +GS S S + + T Q P+ K
Sbjct: 3341 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 3400
Query: 896 ----IRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS--SSEESDSDGEAPAAV 949
+A + + TP S+ G+ ++S + SS + + +PA
Sbjct: 3401 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 3460
Query: 950 TSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA 1009
T++ +++ + + P +T S R EST SS+
Sbjct: 3461 TTSGLVEESTTY------HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTH-------- 3506
Query: 1010 TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPAS 1069
T P + +V PT++ +P ++ A++ S + G+ +E A+ S+ +
Sbjct: 3507 TISSAPSTTSALVEEPTSY-HSSPGST---ATTHFPDSSTTSGRSEESTASHSSQDATGT 3562
Query: 1070 LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1129
+ L + + S P + + ++ + + T P S +ST+ + P+
Sbjct: 3563 IVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGLSEKSTTFHSS-------PR 3614
Query: 1130 LPEVQQATKAPESSDDSEDSSDSSS--GSEEDGEGPQG------AKSAHTLGPTPSRTET 1181
P + + SS SE+S+ S S GS P ++ + T +P T+T
Sbjct: 3615 SPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 3674
Query: 1182 LV----EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1237
+ T+ S E S ++PG T A S ++T S S +TL
Sbjct: 3675 TLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF- 3733
Query: 1238 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1297
PD + +A+ + TG +P S P + T ++ T
Sbjct: 3734 ---PDSTTSSGIVEASTRVHSSTGSPRTT--LSPASSTSPGLQGESTAFQTHPASTHTT- 3787
Query: 1298 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1357
P P + A + V+ T SS S K + P A
Sbjct: 3788 -----PSPPSTA---TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 3839
Query: 1358 --TPRSKKKKKLGAGEGGEASVSPEKTSTTS 1386
TP S G GE + +SP T T+
Sbjct: 3840 GTTPSSAHSTTSGRGESTTSRISPGSTEITT 3870
Score = 93.6 bits (231), Expect = 1e-18
Identities = 269/1324 (20%), Positives = 429/1324 (32%), Gaps = 219/1324 (16%)
Query: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
S + SE S + T A S S ++G S + + TE G++
Sbjct: 1626 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI---SSGSTETTALPGST 1682
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA---AKPGMVSAGQ 195
+ K+ S +SP + P++ T+ E S G+ A PG +
Sbjct: 1683 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 1742
Query: 196 ADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGG 255
S + SS TD ++ P ASS+ + + + PG
Sbjct: 1743 VSQESTASHSSPGSTDT----TLSPGSTTASSLGPESTTFHSS---PGSTETTL------ 1789
Query: 256 ALPPAKRAKKPEEESES--SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGK 313
LP A E S S GS +PAG+ ++ S S P+ K
Sbjct: 1790 -LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTF-----QSWPSS----K 1839
Query: 314 GATPAPPGKAGAVA--SQTKAGKPEEDSESSSEESSDS---EEETPAAKALLQAKASGKT 368
PAPP A S T G P + SS + EE+ + A A+ +
Sbjct: 1840 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 1899
Query: 369 SQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK 428
S +ES ++P + +G+ EE S S + + P+
Sbjct: 1900 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS--- 1956
Query: 429 PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 488
SA +E ++P T + G+ EE + S S + +
Sbjct: 1957 ---------TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 2007
Query: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG--------KVGPATPSAQVGK 540
L A + V LG+S P S+ M PG P +P+ +
Sbjct: 2008 LPARSTTSVL-LGEST-TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP 2065
Query: 541 WEEDSESSSEES--SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQ 598
S SEES S S G T P + G L T+S + +
Sbjct: 2066 ASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG--LSRHSTTSHSSPGSTDTTLLPAS 2123
Query: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ--------------------------- 631
P S +S S S D+ +P + TA
Sbjct: 2124 TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS 2183
Query: 632 --AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA--PRKAGTATSPAGSSPAVAGGTQ 687
+ + ++ + P+ T + AS+ ++ + A A T T+P+ S A A
Sbjct: 2184 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATA---- 2239
Query: 688 RPAEDSSSSEESDSEEEKTGLAV-----------TVGQAKSVGKGLQVKAASVPVKGSLG 736
P E+S++ S T T+ + G +A G
Sbjct: 2240 -PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 2298
Query: 737 QGTAPVLPGKT------GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQA 790
T+ + PG T G T T +E SS + + AS + + T +
Sbjct: 2299 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 2358
Query: 791 KANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV 850
++ P + + + + + PG + + SP + V P+ T RG
Sbjct: 2359 RSQPGSTHSTVSPASTTTPG-LSEESTTVYSSSPGSTETTVF-PRTPTTSVRGEEPTTFH 2416
Query: 851 GKAVATAAQAQTGPEEDSGSSEEES--------------------DSEEEAETLAQVKPS 890
+ +T T SG +EE + D EE+ T S
Sbjct: 2417 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 2476
Query: 891 ---------GKTHQIRAALAPAKESPRKGAAPTPPGK--------------TGPSAAQA- 926
T + P++ SP T PG T P + A
Sbjct: 2477 TGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 2536
Query: 927 ---GKQDDSGSSSEESDSDGEAPAAVTSA--QVIKPPLIFVDPNRSPAGPAATPAQAQAA 981
SG S E S S + + T+A P + S + P +T A
Sbjct: 2537 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2596
Query: 982 STPRKARASESTARSSSSESEDEDVIP-ATQCLTPGIRTNVV------TMPTAHPRIAPK 1034
ST + EST SS S D + P +T L+ G + T T P
Sbjct: 2597 STTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS 2656
Query: 1035 ASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVART 1094
+ + AS+ SS S P T +S + S L + + +T
Sbjct: 2657 SGIVEASTRVHSSTGS-------PRTTLSPASSTSPGL-------------QGESTTFQT 2696
Query: 1095 QPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS 1154
P+S T P+ +T+ + T R P + +S SE S+ S
Sbjct: 2697 HPAS-----THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 2751
Query: 1155 GSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1214
+ G P A S T R E+ + S+E + S + TPGL+ A
Sbjct: 2752 SPDASGTTPSSAHST-----TSGRGESTTSRISPGSTEITTLPGSTT------TPGLSEA 2800
Query: 1215 NS--QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQ 1272
++ +S +P SP+ ++L ++ ++P +SP AS TTP
Sbjct: 2801 STTFYSSPRSPTTTLSPASMTSLGVGEE-STTSRSQPGSTHSTVSP-------ASTTTPG 2852
Query: 1273 KSRK 1276
S +
Sbjct: 2853 LSEE 2856
Score = 85.9 bits (211), Expect = 3e-16
Identities = 213/1067 (19%), Positives = 361/1067 (33%), Gaps = 162/1067 (15%)
Query: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG-- 385
S T +G EE + S S + P+ A KTS + +AS P
Sbjct: 214 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 273
Query: 386 -----------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA--PAQAKPSGK 432
++P P +T +G E+ + S S + A + P
Sbjct: 274 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 333
Query: 433 APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGK--------QEEDSRSSSEESDS 484
+ S P P GP + + + S E+ +
Sbjct: 334 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 393
Query: 485 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED 544
+ + P + +T P K P P G T SA V
Sbjct: 394 PVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSG-----TTSAFV------ 442
Query: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSP---AKGPPQKAGPVAVQVK 600
S++ SS SS PT A +LG+ ++ P SSP A PP + V+
Sbjct: 443 KLSTTYHSSPSS---TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVE 499
Query: 601 AEKPMDNSESS-------EESSDSADSEEAPA-------------AMTAAQAKPAL--KI 638
S S E S+ S SEE+ + TAA A + +
Sbjct: 500 ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL 559
Query: 639 PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE 698
T+ + ++T S + + +P T PAGS+P+V G P+ SS S E
Sbjct: 560 GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSME 619
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ T + GL K+ + ++P P T + +
Sbjct: 620 T-----------TALPGSTTKPGLSEKSTTF--------YSSPRSPDTTHLPASMTSSGV 660
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E+S +S S A P ++ ++ + A+ +P T +PG TA++
Sbjct: 661 SEESTTSHSRPGSTHTTAFPG---STTMPGLSQESTASHSSPGPTDTTLSPGS-TTASSL 716
Query: 819 AKQRSPSKVKPPVRN----PQNSTVLARGPASVP----------SVGKAVATAAQAQTGP 864
+ + +P P N+T AS+P ++ A +T Q ++
Sbjct: 717 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGES-T 775
Query: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT----G 920
S S +++ T A V+PS +H +++ S R + T
Sbjct: 776 TFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS 835
Query: 921 PSAAQA---GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
P + Q + D + EES + + S+ + +P + P +T
Sbjct: 836 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 895
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASM 1037
S+ R+ ESTA SS ++ V+PA + ++ +P +S
Sbjct: 896 HFPDSSTTSGRSEESTASHSSQDATGTIVLPA---------RSTTSVLLGESTTSPISSG 946
Query: 1038 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPS 1097
+ +++ S + G + S ++PA+ T + + SE + +R++P
Sbjct: 947 SMETTALPGSTTTPGLSERSTTFHSSPRSPAT---TLSPASTTSSGVSE-ESTTSRSRPG 1002
Query: 1098 SGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDS-----SDS 1152
S T P ST+ + P T P S+ S S S S
Sbjct: 1003 S-------THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 1055
Query: 1153 SSGSEEDGEGP---------QGAKSAH--------TLGPTPSRTETLVEET----AAESS 1191
SSGS + P Q + + H TL P + + +VE + ++ S
Sbjct: 1056 SSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 1115
Query: 1192 EDDVVAPSQSL---LSGYMTPGLT-PANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1247
++P+ S L G T T PA++ + + P ++P ST +
Sbjct: 1116 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 1175
Query: 1248 KPQQA--AGMLSPKT--GGKEAASGTTPQKSRKPKKGAGNPQASTLA 1290
P + +G T ASGTTP + G G S ++
Sbjct: 1176 FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 1222
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 105 bits (261), Expect = 4e-22
Identities = 251/1155 (21%), Positives = 391/1155 (33%), Gaps = 196/1155 (16%)
Query: 235 ARKAAPAPGKVGDVTPQVKGGALPP--------------AKRAKKPEEESESSEEGSESE 280
A PA G +TP+ G PP +KP E G+
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 281 EEAP-------AGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAG 333
E AP AGT S+ AS R AP P K +P P G + T+ G
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAP----PAKNTSPGPVSSPGRASGTTRPG 127
Query: 334 K-PEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAA----- 387
++ S+EE+ + T A K + + + + P+ R+ A
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 388 ----PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA 443
PAP + P G R+ S S+SE S +E A+ +PS R PA
Sbjct: 188 GLPRPAPSARPRPPTE----GPRKSVS-SASEHSTTEPSPAARRRPSAGGGLQR----PA 238
Query: 444 KESPRKGAAP-APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK 502
S A P + P ++GP+A R+ + S + L A+ QV P K
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTP--------RAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 503 --SPQVKPASTMGMG---PLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 557
+P + P S+ + P G A PVPP ATP S
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPD-NAATPLPAT-------------LPPSPP 336
Query: 558 GEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAGP---VAVQVKAEKPMDNSESSE 612
P +AP + ++ L + P + P++ PP P ++ P+ S
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL- 395
Query: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKAC-------PKKTNTTASAKVAPVRVGTQA 665
+S S + +P A+++ QA +L P +A P++T + ++ P +
Sbjct: 396 -TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454
Query: 666 PRKAGTATSPAGS----------SPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA 715
P + PA SP + T P + SS + + L + +
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
Query: 716 KS--VGKGLQVKAASV--PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDS 771
+S LQ AS+ P +L P L + P T E ++
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP-HLETPPCPAPCPLQAPP 573
Query: 772 EEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV 831
P + +S+ +A PA A +P +G S P + A Q P PP+
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALA-SPPLQGLPSPP--LSPLATPPPQAPPXLALPPL 630
Query: 832 RNPQNSTVLAR-GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETL------ 884
+ P + P + PS A A P S ++ A
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
Query: 885 --AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 942
+Q PS ++ +P P +A PP P AA + S +S
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750
Query: 943 GEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESE 1002
P V PPL+ P + P P A+ + A P +A + +T + S
Sbjct: 751 ATPPPRV-------PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Query: 1003 DEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQV 1062
P +P + + T P+ P + P QV
Sbjct: 804 PAS-FPGQAPFSPSASLPMSPLATPPPQAPPVLA--------------------APLLQV 842
Query: 1063 SKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGT 1122
PAS P QA R P+ G D++V + P+ T A G
Sbjct: 843 PPSPPAS-PTLQAP----------------RRPPTPGPDTSV-----SGPRLTLALAPG- 879
Query: 1123 NKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEE---DGEGPQGAKSAHTLGPTPSRT 1179
P P + + D + SS ++S EE GP+G +A P P
Sbjct: 880 -----PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA---SPPP--- 928
Query: 1180 ETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKD 1239
+ ++ A + S P L + + + P + L
Sbjct: 929 ------------DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 976
Query: 1240 DPDGKQEAKPQQAAGML----SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1295
+ +G + A P A G L SP T G +AA+G S + K A + ALQ+++
Sbjct: 977 ETEGPESATP--APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 1034
Query: 1296 TQCLLGQPWPLNEAQ 1310
Q LL + L A+
Sbjct: 1035 VQHLLSRTLLLAAAE 1049
Score = 75.5 bits (184), Expect = 4e-13
Identities = 237/1089 (21%), Positives = 354/1089 (32%), Gaps = 130/1089 (11%)
Query: 59 LGRKRKAEE----------DAALQAKKTRVSDPISTSESSEEEEEAEAETA----KATPR 104
+GRK AE ++A +A TR + S + +S E A +P
Sbjct: 53 VGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG 112
Query: 105 LASTNSSVLGADLPSSMKEK----AKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKS 160
S+ G P + +K + ET GK + A SG +P
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
Query: 161 AEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSV-- 218
+ A + + TE PA A +P ++ SS+ + S++ +PS
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 219 ---KPAQVKASSVSTK-ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSE 274
+PA SS +T SPAR A G P P +A +P + + +
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGT--PRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 275 EGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAG- 333
+ + A S A+ +A P P ATP P + T
Sbjct: 291 DAA----PALGPLSSSPLATPSPSGTKARPVP---PPDNAATPLPATLPPSPPLATPLPL 343
Query: 334 KPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK 393
P S S ++ S TP ++A + + P + P +P+
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403
Query: 394 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453
P + S + +P Q + S +P S PA P
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP-----SRPASTPPDSPPLQ 458
Query: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
AP + PA+ +Q S SS + +AL+++ SPQ P S++
Sbjct: 459 AP--LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL-------ASHSPQA-PLSSLI 508
Query: 514 MGPLGKGAGPVPPGKVGP-----ATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 568
M PL + PP P P + ++ + E P AP
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 569 EKSLGNILQAKPTSSPAK--GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 626
++ + L P +P+ PP +A P A P+ S S P A
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPAL----ASPPLQGLPSPPLS---------PLA 615
Query: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRV-GTQAPRKAGTATSPAGSSPAVAGG 685
QA P L +P +A P + AS ++P+ QAP A SP +
Sbjct: 616 TPPPQAPPXLALPPLQAPP---SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672
Query: 686 TQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG 745
Q P +S S S A QA L VP + P+ P
Sbjct: 673 VQAPFSPPASPPVSPS-------ATPPSQAP---PSLAAPPLQVPPS---PPASPPMSPS 719
Query: 746 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 805
T P AA P QV S +P+A P
Sbjct: 720 ATPP------------------PQAPPPLAAPPLQVPPS-PPASPPMSPSATPPPRVPPL 760
Query: 806 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGP-ASVPSVGKAVATAAQAQTGP 864
++AP V + A KPP PQ LA P ++PS + QA P
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPP---PQAPPALATPPLQALPS--PPASFPGQAPFSP 815
Query: 865 EEDSGSSEEESDSEEEAETLA----QVKPSGKTHQIRAALAPAKESPRKGAAPTP-PGKT 919
S + + LA QV PS +P ++PR+ P P +
Sbjct: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPS-------PPASPTLQAPRRPPTPGPDTSVS 868
Query: 920 GP--SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
GP + A A S S S G A +S+ P + + G AA+P
Sbjct: 869 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM-PTAHPRIAPKAS 1036
+ A S A + +P PG + T+ T P A A
Sbjct: 929 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA- 987
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1096
GA S S GK G S ++P L + L L +AS Q ++RT
Sbjct: 988 -PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL--QASVVQHLLSRTLL 1044
Query: 1097 SSGVDSAVG 1105
+ + A G
Sbjct: 1045 LAAAEGAAG 1053
Score = 73.6 bits (179), Expect = 1e-12
Identities = 195/940 (20%), Positives = 315/940 (33%), Gaps = 127/940 (13%)
Query: 430 SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV-----QVGKQEEDSRS------- 477
+G A + AA AP +PR +P PP PAA +V VG++ R+
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 478 ---SSEESDSDREA-LAAMNAAQVKPL-GKSPQVKPASTMGMGPL---GKGAGPVPPGKV 529
S+ + R A ++ N A P G+ + PA GP+ G+ +G PG +
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 530 G------PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA-----QEKSLG-NILQ 577
G A + GK E + S+ + D PT P+ + ++ G +
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 578 AKPTSSPAKGPPQKAGPVAVQVKAE------------KPMDNSESSEESSDSADSEEAPA 625
+P S PP + +V +E +P +S S S P
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 626 AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGG 685
+ A A P+ A P + + P +V T + A A P SSP
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV-TPPRKDAAPALGPLSSSPL---A 305
Query: 686 TQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP--VL 743
T P+ + + + T L T+ + + L + S SL +P
Sbjct: 306 TPSPS-GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
Query: 744 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK 803
P + P++T + ++ P QV S+ +A P+ S +
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQT-----------IPPIQVPHSLTSPSLQAPPSPLALSSLQ 413
Query: 804 GTIS-------APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 856
T S A +T + + Q S + P P +S L + P S+P+ +
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL-QAPLSLPA-----SP 467
Query: 857 AAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI-------RAALAPAKESPRK 909
Q P SS + +LA P + +++LAP
Sbjct: 468 PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527
Query: 910 GAAPTPPGKTGPSAAQAGKQDDS--------------------GSSSEESDSDGEAPAAV 949
+ TPP + PS A Q S S + E P+++
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Query: 950 TSAQVIKPPLIFVDPNRS----PAGPAATP---AQAQAASTPRKARASESTARSSSSESE 1002
+ PP + P + P P ATP A A P +A S + S +
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647
Query: 1003 DEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQ-EGPATQ 1061
P L + + P + P AP + A S ++ S P Q
Sbjct: 648 PSPQAP--NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 1062 VSKKNPASLPLTQAALKVLAQKASEAQPP--VARTQPSSGVDSAVGTLPATSP---QSTS 1116
V PAS P++ +A A PP V + P+S S T P P +
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 1117 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGP-- 1174
+Q + P P + +AP + + S + G+ P ++ + P
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
Query: 1175 ------TPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSS 1228
P L++ + + + AP + G T P + A P S
Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885
Query: 1229 PSVSSTLAAKD--DPDGKQEAKPQQAAGMLSPKTGGKEAA 1266
S SSTL+ D + P++ G S GG A+
Sbjct: 886 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
Score = 50.8 bits (120), Expect = 1e-05
Identities = 125/544 (22%), Positives = 171/544 (31%), Gaps = 75/544 (13%)
Query: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA-AKALLQA 362
+ P TP ATP PP A+AS G P S S ++ + P A LQA
Sbjct: 577 TTPPPETPSSIATP-PPQAPPALASPPLQGLP---SPPLSPLATPPPQAPPXLALPPLQA 632
Query: 363 KASGKTSQ-VGAASAPAKESPRKGA-----APAPPGKTGPAVAKAQAGKREEDSQSSSEE 416
S S + + P+ ++P A AP P + P A S +S
Sbjct: 633 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--------SPPASPP 684
Query: 417 SDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAA---QVQVGKQEE 473
P+QA PS AP ++ +P P +A PP+ P AA QV
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP-- 531
S S L A QV P P +++ M PL K PP P
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPP-------SPPASLPMSPLAKPPPQAPPALATPPL 797
Query: 532 -ATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP-- 588
A PS + S S S P P L + + P S + P
Sbjct: 798 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 857
Query: 589 PQKAGP----------VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKI 638
P GP +A+ P S SS S + A T + +
Sbjct: 858 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 917
Query: 639 PQ--TKACPKKTNTTASAKVAPVRVGTQAPRK-AGTATSPAGSSPAVAGGTQRPAEDSSS 695
P+ A P A+ A G P G +P PA G+ A+ +
Sbjct: 918 PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS---ADGLCT 974
Query: 696 SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK 755
E++ E T P G+L G +P G G
Sbjct: 975 IYETEGPESAT-----------------------PAPGALDPGPSPGTSG--GKAAAGAG 1009
Query: 756 AEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTA 815
A S + A + V+ + +T A A S G A G VT
Sbjct: 1010 AGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG 1069
Query: 816 AAQA 819
A+A
Sbjct: 1070 GARA 1073
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 99.4 bits (246), Expect = 2e-20
Identities = 248/1229 (20%), Positives = 412/1229 (33%), Gaps = 149/1229 (12%)
Query: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL- 113
+T+ G K+ + ++ P ST+ +E + + ST++++
Sbjct: 219 RTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG-----STDTTLSP 273
Query: 114 GADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTL--VS 171
G PSS+ ++ G T + T T + LL +P S+ S +TTL S
Sbjct: 274 GTTTPSSLGPESTTFHSSPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPAS 331
Query: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
T EG F + S + ++S S T PS P S+ ST
Sbjct: 332 STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLS---TTYHSSPSSTPT-THFSASSTT 387
Query: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS---EEGSESEEEAPAGTR 288
+ ++ P +P PPA+ A E ++ GS P +
Sbjct: 388 LGHSEESTPVHS-----SPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST 442
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
+ + E + + TP A A ++ S + + S E S
Sbjct: 443 TSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESK 502
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE 408
+ +P A A A S + S P+ S A PG T + G E+
Sbjct: 503 ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST------TKPGLSEK 556
Query: 409 DSQS-SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
+ SS S PA SG + +ES + P T +
Sbjct: 557 STTFYSSPRSPDTTHLPASMTSSGVS----------EESTTSHSRPGSTHTTAFPGSTTM 606
Query: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQV----------KPLGKSPQVKPASTMGMGPL 517
G +E + S S +D A +P + P +T G L
Sbjct: 607 PGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLL 666
Query: 518 GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ 577
+ + PV P T + G ES++ S SS+ PA + ++
Sbjct: 667 -EASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSND-----TRPAPPTTTSAFVE 720
Query: 578 AKPTS--SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPA 635
TS SP+ P ++ + ++ S + S S + P + T +
Sbjct: 721 PSTTSHGSPSSIPTTH---ISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGE- 776
Query: 636 LKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS 695
++ ++TT + AP +SP ++ + + S
Sbjct: 777 ------ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 830
Query: 696 SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK 755
S S S ++ TG V A+S L ++ + P+ + TA LPG T T
Sbjct: 831 SIASHSSQDATGTIVL--PARSTNSVLLGESTTSPISSGSMETTA--LPGST---TTPGL 883
Query: 756 AEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTA 815
+E+ SS + + AS S + T + + P + + + + PG ++
Sbjct: 884 SERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG--LSR 941
Query: 816 AAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 875
+ SP + +T L P + P + +T A G +G SE+ +
Sbjct: 942 HSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPI--SSGSTETTALPGSTTTAGLSEKST 999
Query: 876 DSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT------GPSAAQAGKQ 929
T S T A+ + S + + PG T G + Q
Sbjct: 1000 -------TFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ 1052
Query: 930 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 989
+ + S S +D T+A + P + +GP +T +T
Sbjct: 1053 ESTASHSSPGSTDTTLSPRSTTASSLGP-----ESTTFHSGPGSTETTLLPDNTTASGLL 1107
Query: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
ST SS+ S + PA G T + P++ + A S+ E S
Sbjct: 1108 EASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMP--APPTTTSAFVELSTT 1165
Query: 1050 SDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA 1109
S G +P+S+P T + A + + + T SS V A PA
Sbjct: 1166 SHG-------------SPSSIPTTHFS----ASSTTFGRSEESTTVHSSPVAPATTPSPA 1208
Query: 1110 TSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA 1169
S S V+ P Q PESS S S +S + + +
Sbjct: 1209 RSTTSGLVEESTAYH----SSPGSTQTMHFPESSTASGRSEESRTSH---------SSTT 1255
Query: 1170 HTLGPTPSRTETLVEETAAESSEDDVVA----PSQSLLSGYM-----------TPGLTP- 1213
HT+ PS T LVEE + S +A P S SG T G+TP
Sbjct: 1256 HTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPL 1315
Query: 1214 -----ANSQASKATPKLDSSPSVSSTLAA 1237
+ + +++T S S+ +TLA+
Sbjct: 1316 PAHFTTSGRIAESTTFYISPGSMETTLAS 1344
Score = 79.7 bits (195), Expect = 2e-14
Identities = 218/1071 (20%), Positives = 359/1071 (33%), Gaps = 155/1071 (14%)
Query: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG-- 385
S T +G EE + S S + P+ A KTS + +AS P
Sbjct: 135 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 194
Query: 386 -----------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA--PAQAKPSGK 432
++P P +T +G E+ + S S + A + P
Sbjct: 195 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 254
Query: 433 APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGK--------QEEDSRSSSEESDS 484
+ S P P GP + + + S E+ +
Sbjct: 255 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 314
Query: 485 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED 544
+ + P + +T P K P P G T SA V
Sbjct: 315 PVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSG-----TTSAFV------ 363
Query: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSP---AKGPPQKAGPVAVQVK 600
S++ SS SS PT A +LG+ ++ P SSP A PP + V+
Sbjct: 364 KLSTTYHSSPSS---TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVE 420
Query: 601 AEKPMDNSESS-------EESSDSADSEEAPA-------------AMTAAQAKPAL--KI 638
S S E S+ S SEE+ + TAA A + +
Sbjct: 421 ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL 480
Query: 639 PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE 698
T+ + ++T S + + +P T PAGS+P+V G P+ SS S E
Sbjct: 481 GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSME 540
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ T + GL K+ + ++P P T + +
Sbjct: 541 T-----------TALPGSTTKPGLSEKSTTF--------YSSPRSPDTTHLPASMTSSGV 581
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E+S +S S A P ++ ++ + A+ +P T +PG TA++
Sbjct: 582 SEESTTSHSRPGSTHTTAFPG---STTMPGLSQESTASHSSPGPTDTTLSPGS-TTASSL 637
Query: 819 AKQRSPSKVKPPVRN----PQNSTVLARGPASVP----------SVGKAVATAAQAQTGP 864
+ + +P P N+T AS+P ++ A +T Q ++
Sbjct: 638 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGES-T 696
Query: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT----G 920
S S ++ T A V+PS +H +++ S R + T
Sbjct: 697 TFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS 756
Query: 921 PSAAQA---GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
P + Q + D + EES + + S+ + +P + P +T
Sbjct: 757 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 816
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPA------------TQCLTPG-IRTNVVTM 1024
S+ R+ ES A SS ++ V+PA T ++ G + T +
Sbjct: 817 HFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPG 876
Query: 1025 PTAHPRIAPKAS------MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLT----Q 1074
T P ++ +++ + A++ +S S G +E + S P S T
Sbjct: 877 STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEE---STTSHSRPGSTHTTAFPDS 933
Query: 1075 AALKVLAQKASEAQPPVARTQ----PSSGVDSAVGTLPATSP------QSTSVQAKGTNK 1124
L++ ++ + T P+S VG P TSP ++T++ T
Sbjct: 934 TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGE-PTTSPISSGSTETTALPGSTTTA 992
Query: 1125 LRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLV- 1183
K + ++P+++ S S+ SS SEE S HT S T V
Sbjct: 993 GLSEKSTTFYSSPRSPDTT-LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVS 1051
Query: 1184 -EETAAES---SEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKD 1239
E TA+ S S D ++P + S T + S T L + + S L A
Sbjct: 1052 QESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEA-S 1110
Query: 1240 DPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLA 1290
P P+ LSP TT Q K P +T A
Sbjct: 1111 TPVHSSTGSPRTT---LSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSA 1158
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 98.2 bits (243), Expect = 5e-20
Identities = 308/1574 (19%), Positives = 558/1574 (35%), Gaps = 246/1574 (15%)
Query: 53 WQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETA--KATPR--LAST 108
W++ + RK K +E A + KK + + + T E + E +E TA +A P+ S
Sbjct: 307 WRKKTSF-RKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESA 365
Query: 109 NSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
+ L A+ K + +E + +G G S PA T + ++ + +
Sbjct: 366 HEPRLSAEYE---KVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVS 422
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV 228
V E EE Q E S E VE + A+ V
Sbjct: 423 TVEERTEE------------------QKTEVEETAGSVPAEELVEMDAEPQEAEPAKELV 464
Query: 229 STKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
KE+ P G D++P K + PP EG SE E ++
Sbjct: 465 KLKETCVSGEDPTQG--ADLSPDEKVLSKPP---------------EGVVSEVEM-LSSQ 506
Query: 289 SQVKASEKILQVRAASAPAKGTPGK------GATPAPPGKAGAVASQTKAGKPEEDSESS 342
++K L+ S K GK G G+ V + + + E+ ESS
Sbjct: 507 ERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESS 566
Query: 343 SEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
+ + EE T K L + + G+ + GA S K+ R+G P K K
Sbjct: 567 ASSPEEPEEITCLEKGLAEVQQDGEAEE-GATSDGEKK--REGVTPWASFKKMVTPKKRV 623
Query: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAA-SAPAKESPRKGAAPAPPRKTGP 461
E D + ++ S + ++ S +++ + P E P++ + +
Sbjct: 624 RRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWE--- 680
Query: 462 AAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM-GMGPLGKG 520
A + VG ++ +R S + + + GK + + G G
Sbjct: 681 --ALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPG 738
Query: 521 AGPVPPGKVGPATPSAQVGKWE---------EDSESSSEESSDSS------DGEVPTAVA 565
G P + G T V WE + S+S EE S+ S + P
Sbjct: 739 QGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDT-E 797
Query: 566 PAQEKSLGNILQ-------AKPTSSPAKGPPQKAGPVAVQ-----VKAEKPMDNSESSEE 613
P +E+S +I + +P + P + AGP V A P+ ++ E
Sbjct: 798 PGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVER 857
Query: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
M A QA+ + + P+ KA + + + ++V + +A T
Sbjct: 858 EK-----------MEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATII 906
Query: 674 ---SPAGSSPAVAGGTQRPAEDSSS------SEESDSEEEKTGLAVTVGQAKSVGKGLQV 724
SP+ S +V ++ +++ E +EEE + + + + V
Sbjct: 907 EERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVV 966
Query: 725 KAASVPVKGSLGQGTAPVLPGKTGP-------TVTQVKAEKQ--EDSESSEEESDSEEAA 775
A + + TA L + G T V A Q + +++EE + +E
Sbjct: 967 SEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVE 1026
Query: 776 ASPAQVKTSVKKTQAKANPAAARAPSAK---GTISAPGKVVTAAAQAKQRSPSKVKPPVR 832
++ ++TQ A + GT P V+ +A+ P +
Sbjct: 1027 GGVPDIEEQERRTQEVLQAVAEKVKEESQLPGT-GGPEDVLQPVQRAEAERPEEQAEASG 1085
Query: 833 NPQNSTVLARGPASVPSVGKAVATAAQAQTGPE--EDSGSSEEESDSEE-----EAETLA 885
+ + V+ + A QT PE E + E +S E +AETLA
Sbjct: 1086 LKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLA 1145
Query: 886 QVKPSGKTHQIRAALAPAK-----ESPRKGAAPTP----PGKTGPSAAQAGKQDDSGSSS 936
VK + A+ P +S G+ P PG T +++ +S
Sbjct: 1146 GVKSQEMV--MEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASG 1203
Query: 937 EESDSDGEAPAAVTSAQVIKPP----LIFVDPNRSPAGPAATPAQAQ---AASTPRKARA 989
+S G A AQ +PP +F + + + T + T
Sbjct: 1204 TQS---GGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSK 1260
Query: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
+E T + E +P + L I T + +A K E +
Sbjct: 1261 TEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKG---------EGTEE 1311
Query: 1050 SDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA 1109
++ KK + Q K+P S P+ + + + ++ +EA+P + ++AV
Sbjct: 1312 AECKKDDALELQSHAKSPPS-PVEREMVVQVEREKTEAEPTHVNEEKLEH-ETAVTVSEE 1369
Query: 1110 TSPQSTSVQ-------AKGTNKLRKPKLPEV--QQATKAPESSDDSEDSSDSSSGSEED- 1159
S Q AK + L P + ++A SE S ++ +EE+
Sbjct: 1370 VSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEK 1429
Query: 1160 --GEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQ 1217
GE ++ TL P+ ++EE ++E +ED P + + T + Q
Sbjct: 1430 VLGETANILETGETL--EPAGAHLVLEEKSSEKNEDFAAHPGEDAVP-------TGPDCQ 1480
Query: 1218 ASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKP 1277
A K+TP + S+ ++ D +G++ + + + + +E + +P
Sbjct: 1481 A-KSTPVIVSA---TTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIE-DLEP 1535
Query: 1278 KKGAGNPQASTLALQSNITQCLLGQ---------PWPLNEAQVQASVVKVLTELLEQERK 1328
+ G + + L NI Q + Q +E Q QA V+K ++ QE +
Sbjct: 1536 ENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETE 1595
Query: 1329 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTS-K 1387
K + + S++ K + A S K + EAS EKT T +
Sbjct: 1596 KEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMS-----EAS---EKTMTVEVE 1647
Query: 1388 GKAKRDKASGDV---KEKKGKGSLGSQGAKDEPE--------EELQKGM----GTVEGGD 1432
G D+ +V E++G G+ G K PE E ++K + +G D
Sbjct: 1648 GSTVNDQQLEEVVLPSEEEGGGA----GTKSVPEDDGHALLAERIEKSLVEPKEDEKGDD 1703
Query: 1433 QSNPKSK-----------------------KEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1469
+P+++ K+K+K D ++ + ++ + ++ KA T +
Sbjct: 1704 VDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQA 1763
Query: 1470 ESPSQKKKKKKKKT 1483
+ QK++++ K+
Sbjct: 1764 QEELQKQERESAKS 1777
Score = 63.9 bits (154), Expect = 1e-09
Identities = 252/1309 (19%), Positives = 440/1309 (33%), Gaps = 185/1309 (14%)
Query: 29 EVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS 88
EV+ S Q+ Q L ++T G+K+K + + P + +S
Sbjct: 499 EVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQ 558
Query: 89 EEEE-EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
EE++ E+ A + + + + +E A ++ EK K P + K
Sbjct: 559 EEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEK--KREGVTPWASFKKM 616
Query: 148 VANLLSGKSPR-----------KSAEPSANTTLVSETEEE--GSV----------PAFGA 184
V + P KSA S+ + SE +EE GSV +
Sbjct: 617 VTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTS 676
Query: 185 AAKPGMVSAGQADSSSEDTSSSSDE------------TDVEGK------PSVKPAQVKAS 226
+ ++ G + + SSS +E D GK + +
Sbjct: 677 VSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHD 736
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAP-- 284
SP + +P G+ K P K K EE+SE S GS E P
Sbjct: 737 PGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDT 796
Query: 285 -AGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSS 343
G + +K + R P A P A S A P + ++
Sbjct: 797 EPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVE 856
Query: 344 EESSDSEE-----ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGA--APAPPGKTGP 396
E ++++ E P KA + SQV +A + R P
Sbjct: 857 REKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISA 916
Query: 397 AVAKAQAGKREEDSQSSSE----ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA 452
+V + E + + E E +EEE P +P P+ R A S A
Sbjct: 917 SVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEP---LPENREARGDTVVS----EA 969
Query: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAM-----NAAQVKPL----GKS 503
P A +G +E S++EE+ A++ + + P+ G
Sbjct: 970 ELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGV 1029
Query: 504 PQVKPASTMGMGPLGKGAGPVP-----PGKVGPATPSAQVGKWE-EDSESSSEESSDSSD 557
P ++ L A V PG GP V + E E E +E S +
Sbjct: 1030 PDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKE 1089
Query: 558 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS 617
+V V AQE Q K +KA V +++ + + ++ E+
Sbjct: 1090 TDVVLKV-DAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQA--ETLAG 1146
Query: 618 ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR----------VGTQAPR 667
S+E M QA P P + P + T S VA V
Sbjct: 1147 VKSQE----MVMEQAIP----PDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEEN 1198
Query: 668 KAGTATSPAGS-SPAVAGGTQRPAEDSS------SSEESDSEE--EKTGLAVTVGQAKSV 718
+ + T G+ + AV +RP SS + E+S E+ E T V+V +
Sbjct: 1199 EVASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSIL 1258
Query: 719 GK--GLQ-------VKAASVP----VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESS 765
K G Q K VP ++GS+ G + + T +K E E++E
Sbjct: 1259 SKTEGTQEADQYADEKTKDVPFFEGLEGSIDTG---ITVSREKVTEVALKGEGTEEAECK 1315
Query: 766 EEES-DSEEAAASP-----AQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 819
++++ + + A SP ++ V++ + +A P + + VT + +
Sbjct: 1316 KDDALELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETA-----VTVSEEV 1370
Query: 820 KQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEE 879
++ V P+ + G + P +G+ A + Q E S + ++ E+
Sbjct: 1371 SKQLLQTVNVPIIDGAKEVSSLEG-SPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEK 1429
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKES-----------PRKGAAPTPP---GKTGPSAAQ 925
A + +G+T + A +E P + A PT P K+ P
Sbjct: 1430 VLGETANILETGETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVS 1489
Query: 926 AGKQDDSGSSSEESDSDGEAPAAVT-SAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 984
A + SD +GE ++ + + + + S A P
Sbjct: 1490 A-----TTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILELET 1544
Query: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK 1044
+ ++ ++ +++ + + AT+ LT ++T AH I + AG + K
Sbjct: 1545 KSSKLVQNIIQTAVDQFVRTEE-TATEMLTSELQTQ------AHV-IKADSQDAGQETEK 1596
Query: 1045 ESSRISDGKKQEGPATQVSKKNPA----------SLPLTQAALKVLAQKASEA----QPP 1090
E + E P T +++ + S +++A+ K + + + Q
Sbjct: 1597 EGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQL 1656
Query: 1091 VARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNK-LRKPKLPEVQQATKAPESSDDSEDS 1149
PS GT ++ A+ K L +PK E PE+ + +
Sbjct: 1657 EEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALAD 1716
Query: 1150 SDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAP 1198
+D+S G ++ G K E ++E S D + P
Sbjct: 1717 TDASGGLTKESPDTNGPKQKE----KEDAQEVELQEGKVHSESDKAITP 1761
Score = 60.1 bits (144), Expect = 2e-08
Identities = 279/1405 (19%), Positives = 483/1405 (34%), Gaps = 247/1405 (17%)
Query: 153 SGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDV 212
S R +P ++ +E E G P+ AA D++++ ++SD
Sbjct: 5 SSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAP----------DTTADPAIAASD---- 50
Query: 213 EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
P+ K Q K +ST A + + + GD+ Q KG + EEE
Sbjct: 51 ---PATKLLQ-KNGQLSTINGVAEQDELSLQE-GDLNGQ-KGALNGQGALNSQEEEEVIV 104
Query: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA 332
+E G E+ V + ++ SA G P +S++
Sbjct: 105 TEVGQRDSED--------VSKRDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNL 156
Query: 333 GKPEEDSESSSEE----------------SSDSEEETPAAKALLQAKASG---------K 367
+ + +ES + + D E+ + L K G K
Sbjct: 157 EELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHK 216
Query: 368 TSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS----SSEESDSEEEA 423
+GA A +KES K + P + A+ E Q+ E + +E+
Sbjct: 217 DPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKE 276
Query: 424 PAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESD 483
P+++ S +P + K+ +G A + + + +V E+ E+ D
Sbjct: 277 PSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVD 336
Query: 484 SDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEE 543
++ + A + + ++ ++ +PA + ++ E
Sbjct: 337 TEEDGKAEVASEKLTASEQAHPQEPAE---------------------SAHEPRLSAEYE 375
Query: 544 DSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK 603
E SEE S G AP + ++ A+ V V E+
Sbjct: 376 KVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAE--------VHVSTVEER 427
Query: 604 PMDNSESSEESSDSADSEEAPAAMTAAQ-AKPALKIPQTK-ACPKKTNTTASAKVAPVRV 661
+ EE++ S +EE Q A+PA ++ + K C + T A ++P
Sbjct: 428 TEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSP--- 484
Query: 662 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 721
K +P E S E S +E+ + + + G
Sbjct: 485 ----DEKV----------------LSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTG 524
Query: 722 LQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQV 781
L+ K + KG G G + TQV A DS S+EE E +A+SP +
Sbjct: 525 LK-KLSGKKQKGKRGGG------DEESGEHTQVPA----DSPDSQEEQKGESSASSPEEP 573
Query: 782 K--TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV 839
+ T ++K A+ A + VT A K+ K + VR P S
Sbjct: 574 EEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKR--VRRPSESDK 631
Query: 840 LAR-GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRA 898
++ +TA++ Q EE GS EE E + + V + +
Sbjct: 632 EDELDKVKSATLSSTESTASEMQ---EEMKGSVEEPKPEEPKRKVDTSV-----SWEALI 683
Query: 899 ALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD-DSGSSSEESDSDGEAPAAVTSAQVIKP 957
+ +K+ R+G++ G GP A Q D +E+ +DG +
Sbjct: 684 CVGSSKKRARRGSSSDEEG--GPKAMGGDHQKADEAGKDKETGTDGILAGSQEH------ 735
Query: 958 PLIFVDPNRSPAGP--AATPAQAQAAS---------TPRKARAS--ESTARSSSSESEDE 1004
DP + + P A +P + + S TPRK S E + S + S E
Sbjct: 736 -----DPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVE 790
Query: 1005 DVIPATQCLTPGIRTNVVTM-----------PTAHPRIAPKASMAGASSSKESSRIS--- 1050
P T+ PG + V++ P AP ++++ S +
Sbjct: 791 HSTPDTE---PGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVV 847
Query: 1051 -----DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1105
D ++E Q ++K+ A P +AA +V +++ SE+Q + + G +A
Sbjct: 848 PLSEYDAVEREKMEAQQAQKS-AEQPEQKAATEV-SKELSESQVHMMAAAVADGTRAAT- 904
Query: 1106 TLPATSPQSTS---------VQAKGT----NKLRKPKLPEVQQATKAPESSDDSEDSSDS 1152
+ SP S V+A+ L + + E + T ++ E D+
Sbjct: 905 IIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDT 964
Query: 1153 SSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLT 1212
E P+ +A T GP + T E +AAE + + V A SQ S T T
Sbjct: 965 VVSEAE--LTPEAVTAAETAGPLGAEEGT--EASAAEETTEMVSAVSQLTDSPDTTEEAT 1020
Query: 1213 PANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQ 1272
P + P ++ + + K+E++ P TGG E P
Sbjct: 1021 PV-QEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQ--------LPGTGGPEDV--LQPV 1069
Query: 1273 KSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVD 1332
+ + ++ +AS L ++++ +V A K TE Q K V
Sbjct: 1070 QRAEAERPEEQAEASGLKKETDVV------------LKVDAQEAK--TEPFTQ-GKVVGQ 1114
Query: 1333 TTKESSRKGWESRKRKLSGDQPA---ARTPRSKKKKKLGAGEGGEASVSPE--KTSTTSK 1387
TT ES K + + S + A T K +++ E ++ P+ +T T S+
Sbjct: 1115 TTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVM----EQAIPPDSVETPTDSE 1170
Query: 1388 GKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSN--PKSKKEKKKS 1445
A D K + E EE + GT GG ++ P K+
Sbjct: 1171 TDGSTPVADFDAPGTTQKDEI------VEIHEENEVASGTQSGGTEAEAVPAQKERPPAP 1224
Query: 1446 DKRKKDKEKKEKKKKAKKASTKDSE 1470
+E KE+ K D E
Sbjct: 1225 SSFVFQEETKEQSKMEDTLEHTDKE 1249
Score = 35.4 bits (80), Expect = 0.41
Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 17/140 (12%)
Query: 1363 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ 1422
K LGAGE P++++ + KR+++ ++ G + K+E EE+ +
Sbjct: 216 KDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEE-CKEEGEEKQE 274
Query: 1423 KGMGTVEGGDQSNPKSK----------------KEKKKSDKRKKDKEKKEKKKKAKKAST 1466
K S S+ ++K K K+D+ + +KKK ++
Sbjct: 275 KEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEK 334
Query: 1467 KDSESPSQKKKKKKKKTAEQ 1486
D+E + + +K TA +
Sbjct: 335 VDTEEDGKAEVASEKLTASE 354
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 98.2 bits (243), Expect = 5e-20
Identities = 308/1574 (19%), Positives = 558/1574 (35%), Gaps = 246/1574 (15%)
Query: 53 WQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETA--KATPR--LAST 108
W++ + RK K +E A + KK + + + T E + E +E TA +A P+ S
Sbjct: 209 WRKKTSF-RKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESA 267
Query: 109 NSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
+ L A+ K + +E + +G G S PA T + ++ + +
Sbjct: 268 HEPRLSAEYE---KVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVS 324
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV 228
V E EE Q E S E VE + A+ V
Sbjct: 325 TVEERTEE------------------QKTEVEETAGSVPAEELVEMDAEPQEAEPAKELV 366
Query: 229 STKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
KE+ P G D++P K + PP EG SE E ++
Sbjct: 367 KLKETCVSGEDPTQG--ADLSPDEKVLSKPP---------------EGVVSEVEM-LSSQ 408
Query: 289 SQVKASEKILQVRAASAPAKGTPGK------GATPAPPGKAGAVASQTKAGKPEEDSESS 342
++K L+ S K GK G G+ V + + + E+ ESS
Sbjct: 409 ERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESS 468
Query: 343 SEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
+ + EE T K L + + G+ + GA S K+ R+G P K K
Sbjct: 469 ASSPEEPEEITCLEKGLAEVQQDGEAEE-GATSDGEKK--REGVTPWASFKKMVTPKKRV 525
Query: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAA-SAPAKESPRKGAAPAPPRKTGP 461
E D + ++ S + ++ S +++ + P E P++ + +
Sbjct: 526 RRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWE--- 582
Query: 462 AAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM-GMGPLGKG 520
A + VG ++ +R S + + + GK + + G G
Sbjct: 583 --ALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPG 640
Query: 521 AGPVPPGKVGPATPSAQVGKWE---------EDSESSSEESSDSS------DGEVPTAVA 565
G P + G T V WE + S+S EE S+ S + P
Sbjct: 641 QGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDT-E 699
Query: 566 PAQEKSLGNILQ-------AKPTSSPAKGPPQKAGPVAVQ-----VKAEKPMDNSESSEE 613
P +E+S +I + +P + P + AGP V A P+ ++ E
Sbjct: 700 PGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVER 759
Query: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
M A QA+ + + P+ KA + + + ++V + +A T
Sbjct: 760 EK-----------MEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATII 808
Query: 674 ---SPAGSSPAVAGGTQRPAEDSSS------SEESDSEEEKTGLAVTVGQAKSVGKGLQV 724
SP+ S +V ++ +++ E +EEE + + + + V
Sbjct: 809 EERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVV 868
Query: 725 KAASVPVKGSLGQGTAPVLPGKTGP-------TVTQVKAEKQ--EDSESSEEESDSEEAA 775
A + + TA L + G T V A Q + +++EE + +E
Sbjct: 869 SEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVE 928
Query: 776 ASPAQVKTSVKKTQAKANPAAARAPSAK---GTISAPGKVVTAAAQAKQRSPSKVKPPVR 832
++ ++TQ A + GT P V+ +A+ P +
Sbjct: 929 GGVPDIEEQERRTQEVLQAVAEKVKEESQLPGT-GGPEDVLQPVQRAEAERPEEQAEASG 987
Query: 833 NPQNSTVLARGPASVPSVGKAVATAAQAQTGPE--EDSGSSEEESDSEE-----EAETLA 885
+ + V+ + A QT PE E + E +S E +AETLA
Sbjct: 988 LKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLA 1047
Query: 886 QVKPSGKTHQIRAALAPAK-----ESPRKGAAPTP----PGKTGPSAAQAGKQDDSGSSS 936
VK + A+ P +S G+ P PG T +++ +S
Sbjct: 1048 GVKSQEMV--MEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASG 1105
Query: 937 EESDSDGEAPAAVTSAQVIKPP----LIFVDPNRSPAGPAATPAQAQ---AASTPRKARA 989
+S G A AQ +PP +F + + + T + T
Sbjct: 1106 TQS---GGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSK 1162
Query: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
+E T + E +P + L I T + +A K E +
Sbjct: 1163 TEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKG---------EGTEE 1213
Query: 1050 SDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA 1109
++ KK + Q K+P S P+ + + + ++ +EA+P + ++AV
Sbjct: 1214 AECKKDDALELQSHAKSPPS-PVEREMVVQVEREKTEAEPTHVNEEKLEH-ETAVTVSEE 1271
Query: 1110 TSPQSTSVQ-------AKGTNKLRKPKLPEV--QQATKAPESSDDSEDSSDSSSGSEED- 1159
S Q AK + L P + ++A SE S ++ +EE+
Sbjct: 1272 VSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEK 1331
Query: 1160 --GEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQ 1217
GE ++ TL P+ ++EE ++E +ED P + + T + Q
Sbjct: 1332 VLGETANILETGETL--EPAGAHLVLEEKSSEKNEDFAAHPGEDAVP-------TGPDCQ 1382
Query: 1218 ASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKP 1277
A K+TP + S+ ++ D +G++ + + + + +E + +P
Sbjct: 1383 A-KSTPVIVSA---TTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIE-DLEP 1437
Query: 1278 KKGAGNPQASTLALQSNITQCLLGQ---------PWPLNEAQVQASVVKVLTELLEQERK 1328
+ G + + L NI Q + Q +E Q QA V+K ++ QE +
Sbjct: 1438 ENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETE 1497
Query: 1329 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTS-K 1387
K + + S++ K + A S K + EAS EKT T +
Sbjct: 1498 KEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMS-----EAS---EKTMTVEVE 1549
Query: 1388 GKAKRDKASGDV---KEKKGKGSLGSQGAKDEPE--------EELQKGM----GTVEGGD 1432
G D+ +V E++G G+ G K PE E ++K + +G D
Sbjct: 1550 GSTVNDQQLEEVVLPSEEEGGGA----GTKSVPEDDGHALLAERIEKSLVEPKEDEKGDD 1605
Query: 1433 QSNPKSK-----------------------KEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1469
+P+++ K+K+K D ++ + ++ + ++ KA T +
Sbjct: 1606 VDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQA 1665
Query: 1470 ESPSQKKKKKKKKT 1483
+ QK++++ K+
Sbjct: 1666 QEELQKQERESAKS 1679
Score = 63.9 bits (154), Expect = 1e-09
Identities = 252/1309 (19%), Positives = 440/1309 (33%), Gaps = 185/1309 (14%)
Query: 29 EVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS 88
EV+ S Q+ Q L ++T G+K+K + + P + +S
Sbjct: 401 EVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQ 460
Query: 89 EEEE-EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
EE++ E+ A + + + + +E A ++ EK K P + K
Sbjct: 461 EEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEK--KREGVTPWASFKKM 518
Query: 148 VANLLSGKSPR-----------KSAEPSANTTLVSETEEE--GSV----------PAFGA 184
V + P KSA S+ + SE +EE GSV +
Sbjct: 519 VTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTS 578
Query: 185 AAKPGMVSAGQADSSSEDTSSSSDE------------TDVEGK------PSVKPAQVKAS 226
+ ++ G + + SSS +E D GK + +
Sbjct: 579 VSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHD 638
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAP-- 284
SP + +P G+ K P K K EE+SE S GS E P
Sbjct: 639 PGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDT 698
Query: 285 -AGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSS 343
G + +K + R P A P A S A P + ++
Sbjct: 699 EPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVE 758
Query: 344 EESSDSEE-----ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGA--APAPPGKTGP 396
E ++++ E P KA + SQV +A + R P
Sbjct: 759 REKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISA 818
Query: 397 AVAKAQAGKREEDSQSSSE----ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA 452
+V + E + + E E +EEE P +P P+ R A S A
Sbjct: 819 SVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEP---LPENREARGDTVVS----EA 871
Query: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAM-----NAAQVKPL----GKS 503
P A +G +E S++EE+ A++ + + P+ G
Sbjct: 872 ELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGV 931
Query: 504 PQVKPASTMGMGPLGKGAGPVP-----PGKVGPATPSAQVGKWE-EDSESSSEESSDSSD 557
P ++ L A V PG GP V + E E E +E S +
Sbjct: 932 PDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKE 991
Query: 558 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS 617
+V V AQE Q K +KA V +++ + + ++ E+
Sbjct: 992 TDVVLKV-DAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQA--ETLAG 1048
Query: 618 ADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR----------VGTQAPR 667
S+E M QA P P + P + T S VA V
Sbjct: 1049 VKSQE----MVMEQAIP----PDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEEN 1100
Query: 668 KAGTATSPAGS-SPAVAGGTQRPAEDSS------SSEESDSEE--EKTGLAVTVGQAKSV 718
+ + T G+ + AV +RP SS + E+S E+ E T V+V +
Sbjct: 1101 EVASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSIL 1160
Query: 719 GK--GLQ-------VKAASVP----VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESS 765
K G Q K VP ++GS+ G + + T +K E E++E
Sbjct: 1161 SKTEGTQEADQYADEKTKDVPFFEGLEGSIDTG---ITVSREKVTEVALKGEGTEEAECK 1217
Query: 766 EEES-DSEEAAASP-----AQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 819
++++ + + A SP ++ V++ + +A P + + VT + +
Sbjct: 1218 KDDALELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETA-----VTVSEEV 1272
Query: 820 KQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEE 879
++ V P+ + G + P +G+ A + Q E S + ++ E+
Sbjct: 1273 SKQLLQTVNVPIIDGAKEVSSLEG-SPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEK 1331
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKES-----------PRKGAAPTPP---GKTGPSAAQ 925
A + +G+T + A +E P + A PT P K+ P
Sbjct: 1332 VLGETANILETGETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVS 1391
Query: 926 AGKQDDSGSSSEESDSDGEAPAAVT-SAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 984
A + SD +GE ++ + + + + S A P
Sbjct: 1392 A-----TTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILELET 1446
Query: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK 1044
+ ++ ++ +++ + + AT+ LT ++T AH I + AG + K
Sbjct: 1447 KSSKLVQNIIQTAVDQFVRTEE-TATEMLTSELQTQ------AHV-IKADSQDAGQETEK 1498
Query: 1045 ESSRISDGKKQEGPATQVSKKNPA----------SLPLTQAALKVLAQKASEA----QPP 1090
E + E P T +++ + S +++A+ K + + + Q
Sbjct: 1499 EGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQL 1558
Query: 1091 VARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNK-LRKPKLPEVQQATKAPESSDDSEDS 1149
PS GT ++ A+ K L +PK E PE+ + +
Sbjct: 1559 EEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALAD 1618
Query: 1150 SDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAP 1198
+D+S G ++ G K E ++E S D + P
Sbjct: 1619 TDASGGLTKESPDTNGPKQKE----KEDAQEVELQEGKVHSESDKAITP 1663
Score = 59.7 bits (143), Expect = 2e-08
Identities = 236/1166 (20%), Positives = 407/1166 (34%), Gaps = 194/1166 (16%)
Query: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS----SSEESDSEEE 422
K +GA A +KES K + P + A+ E Q+ E + +E+
Sbjct: 118 KDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEK 177
Query: 423 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 482
P+++ S +P + K+ +G A + + + +V E+ E+
Sbjct: 178 EPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKV 237
Query: 483 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 542
D++ + A + + ++ ++ +PA + ++
Sbjct: 238 DTEEDGKAEVASEKLTASEQAHPQEPAE---------------------SAHEPRLSAEY 276
Query: 543 EDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE 602
E E SEE S G AP + ++ A+ V V E
Sbjct: 277 EKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAE--------VHVSTVEE 328
Query: 603 KPMDNSESSEESSDSADSEEAPAAMTAAQ-AKPALKIPQTK-ACPKKTNTTASAKVAPVR 660
+ + EE++ S +EE Q A+PA ++ + K C + T A ++P
Sbjct: 329 RTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSP-- 386
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
K +P E S E S +E+ + + +
Sbjct: 387 -----DEKV----------------LSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTST 425
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GL+ K + KG G G + TQV A DS S+EE E +A+SP +
Sbjct: 426 GLK-KLSGKKQKGKRGGG------DEESGEHTQVPA----DSPDSQEEQKGESSASSPEE 474
Query: 781 VK--TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNST 838
+ T ++K A+ A + VT A K+ K + VR P S
Sbjct: 475 PEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKR--VRRPSESD 532
Query: 839 VLAR-GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR 897
++ +TA++ Q EE GS EE E + + V + +
Sbjct: 533 KEDELDKVKSATLSSTESTASEMQ---EEMKGSVEEPKPEEPKRKVDTSV-----SWEAL 584
Query: 898 AALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD-DSGSSSEESDSDGEAPAAVTSAQVIK 956
+ +K+ R+G++ G GP A Q D +E+ +DG +
Sbjct: 585 ICVGSSKKRARRGSSSDEEG--GPKAMGGDHQKADEAGKDKETGTDGILAGSQEH----- 637
Query: 957 PPLIFVDPNRSPAGP--AATPAQAQAAS---------TPRKARAS--ESTARSSSSESED 1003
DP + + P A +P + + S TPRK S E + S + S
Sbjct: 638 ------DPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGV 691
Query: 1004 EDVIPATQCLTPGIRTNVVTM-----------PTAHPRIAPKASMAGASSSKESSRIS-- 1050
E P T+ PG + V++ P AP ++++ S +
Sbjct: 692 EHSTPDTE---PGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAV 748
Query: 1051 ------DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAV 1104
D ++E Q ++K+ A P +AA +V +++ SE+Q + + G +A
Sbjct: 749 VPLSEYDAVEREKMEAQQAQKS-AEQPEQKAATEV-SKELSESQVHMMAAAVADGTRAAT 806
Query: 1105 GTLPATSPQSTS---------VQAKGT----NKLRKPKLPEVQQATKAPESSDDSEDSSD 1151
+ SP S V+A+ L + + E + T ++ E D
Sbjct: 807 -IIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGD 865
Query: 1152 SSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGL 1211
+ E P+ +A T GP + T E +AAE + + V A SQ S T
Sbjct: 866 TVVSEAE--LTPEAVTAAETAGPLGAEEGT--EASAAEETTEMVSAVSQLTDSPDTTEEA 921
Query: 1212 TPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTP 1271
TP + P ++ + + K+E++ P TGG E P
Sbjct: 922 TPV-QEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQ--------LPGTGGPEDV--LQP 970
Query: 1272 QKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVV 1331
+ + ++ +AS L ++++ +V A K TE Q K V
Sbjct: 971 VQRAEAERPEEQAEASGLKKETDVV------------LKVDAQEAK--TEPFTQ-GKVVG 1015
Query: 1332 DTTKESSRKGWESRKRKLSGDQPA---ARTPRSKKKKKLGAGEGGEASVSPE--KTSTTS 1386
TT ES K + + S + A T K +++ E ++ P+ +T T S
Sbjct: 1016 QTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVM----EQAIPPDSVETPTDS 1071
Query: 1387 KGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSN--PKSKKEKKK 1444
+ A D K + E EE + GT GG ++ P K+
Sbjct: 1072 ETDGSTPVADFDAPGTTQKDEI------VEIHEENEVASGTQSGGTEAEAVPAQKERPPA 1125
Query: 1445 SDKRKKDKEKKEKKKKAKKASTKDSE 1470
+E KE+ K D E
Sbjct: 1126 PSSFVFQEETKEQSKMEDTLEHTDKE 1151
Score = 35.4 bits (80), Expect = 0.41
Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 17/140 (12%)
Query: 1363 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ 1422
K LGAGE P++++ + KR+++ ++ G + K+E EE+ +
Sbjct: 118 KDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEE-CKEEGEEKQE 176
Query: 1423 KGMGTVEGGDQSNPKSK----------------KEKKKSDKRKKDKEKKEKKKKAKKAST 1466
K S S+ ++K K K+D+ + +KKK ++
Sbjct: 177 KEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEK 236
Query: 1467 KDSESPSQKKKKKKKKTAEQ 1486
D+E + + +K TA +
Sbjct: 237 VDTEEDGKAEVASEKLTASE 256
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 95.9 bits (237), Expect = 3e-19
Identities = 220/949 (23%), Positives = 320/949 (33%), Gaps = 161/949 (16%)
Query: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSS 205
K V++L+ + +A + + L T E V A A A V +G S +
Sbjct: 20 KVVSDLVGSLESQLAASAAHHHHLAPRTPE---VRAAAAGALGNHVVSG----SPAGAAG 72
Query: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK 265
+ EG P P A + P PG P V G PPA + +
Sbjct: 73 AGPAAPAEGAPGAAPEPPPAG----RARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP 128
Query: 266 PEEESESS-------EEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318
P E S S + E APAG A L RA P G PG G P
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK--PAGPAALAARAGPGPGPG-PGPGPGPG 185
Query: 319 PPGKAGAVASQTKAGKPE-EDSESSSEESSDSEEETPAAKALLQAKASGKT-----SQVG 372
P AG A+QT G +S ++ + PAA L A+ T VG
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245
Query: 373 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432
AA+ PA +P AAPAP A A A + ++ P A P+
Sbjct: 246 AAAPPAPAAPSPPAAPAP-------AAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298
Query: 433 APQVRAASAPAKESPRKGAAPAP-PRKTGPAAAQVQVGKQEEDSRSSS--EESDSDREAL 489
P A A+ GAAPAP P GPA Q G + + + R
Sbjct: 299 PP------AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352
Query: 490 AAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSS 549
AA AAQ L S A++M +GP +GA P P V P P G + + + +
Sbjct: 353 AAPPAAQT--LAASGPASTAASMVIGPTMQGALP-SPAAVPPPAPGTPTGLPKGAAGAVT 409
Query: 550 EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE 609
+ S PTA +L PT + P P +Q P
Sbjct: 410 QSLS-----RTPTATTSGIRATL------TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLV 458
Query: 610 SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT-QAPRK 668
SE ++A A M A A PQT P+ T++ PV++ T QAP
Sbjct: 459 RSENGQLLMIPQQALAQMQA----QAHAQPQTTMAPRPATPTSA---PPVQISTVQAP-- 509
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
+P +A S+ + + L + G + G + AS
Sbjct: 510 ---------GTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTAS 560
Query: 729 VPVKGSLGQGTAP-VLPGKT------GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQV 781
+ ++ GT +PG T T+ VK K S + S +++ + A V
Sbjct: 561 LGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANV 620
Query: 782 K----------------TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
K TS + ++P P K ++ A ++ +A Q+S
Sbjct: 621 KELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQ 680
Query: 826 KVKPPVRNPQNS-TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETL 884
+ PP + T + + + GK AT A P +L
Sbjct: 681 QPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPP----------------VLSL 724
Query: 885 AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE 944
Q G Q + ++ P+ GA PP T +
Sbjct: 725 TQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNR---------- 774
Query: 945 APAAVTSAQVIK----PPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
+T+ Q I+ P+ V P P A + AQAA+ +K + E S +
Sbjct: 775 --IMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAA-QKNKLKEPGGGSFRDD 831
Query: 1001 SEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
+ DV ASMAG + S+ES+RI
Sbjct: 832 DDINDV----------------------------ASMAGVNLSEESARI 852
Score = 85.1 bits (209), Expect = 5e-16
Identities = 155/640 (24%), Positives = 226/640 (35%), Gaps = 79/640 (12%)
Query: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVA 327
+E S+ E + A + + +VRAA+A A G +PA G AGA
Sbjct: 18 DEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPA--GAAGAGP 75
Query: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG-- 385
+ G P + E PA +A + G G P SPR+
Sbjct: 76 AAPAEGAP-----------GAAPEPPPAGRA----RPGG-----GGPQRPGPPSPRRPLV 115
Query: 386 -AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK 444
A PAPP + AG +++ + E AKP+G A A
Sbjct: 116 PAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175
Query: 445 ESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP 504
P G P P + GP AAQ G S+ +S A A++ P P
Sbjct: 176 PGPGPGPGPGPGKPAGPGAAQTLNG--------SAALLNSHHAAAPAVSLVNNGPAALLP 227
Query: 505 QVKPAST---------MGMGPLGKGAGPVPPGKVGPATP-SAQVGKWEEDSESSSEESSD 554
KPA+ +G A P PP PA P +A + +
Sbjct: 228 LPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP 287
Query: 555 SSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ----KAGPVAVQVKAEKPMDNSES 610
+ AV P G A P +PA G P + GP A A P +ES
Sbjct: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA-AAAPAPGVKAES 346
Query: 611 SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAG 670
+ +A PAA T A + PA T A T A +P V AP G
Sbjct: 347 PKRVVQAA----PPAAQTLAASGPA----STAASMVIGPTMQGALPSPAAVPPPAP---G 395
Query: 671 TATS-PAGSSPAVAGGTQR-PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T T P G++ AV R P +S + + Q + + Q+
Sbjct: 396 TPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGM 455
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V V+ GQ ++P + + Q++A+ +++ + +A P Q+ T
Sbjct: 456 VLVRSENGQ--LLMIPQQ---ALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIST----V 506
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
QA P AR + I K V+ A Q S + + P PQ ++ G A
Sbjct: 507 QAPGTPIIARQVTPTTII----KQVSQAQTTVQPSATLQRSPGVQPQ---LVLGGAAQTA 559
Query: 849 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK 888
S+G ATA Q T G++ S + E E + + K
Sbjct: 560 SLG--TATAVQTGTPQRTVPGATTTSSAATETMENVKKCK 597
Score = 55.5 bits (132), Expect = 4e-07
Identities = 232/1101 (21%), Positives = 369/1101 (33%), Gaps = 209/1101 (18%)
Query: 472 EEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG-------PLG-KGAGP 523
E D + S+ S LAA A ++P+V+ A+ +G P G GAGP
Sbjct: 16 EVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGP 75
Query: 524 VPP--GKVGPATPSAQVGKWEEDSESSSEESSDS------SDGEVPTA--VAPAQEKSLG 573
P G G A G+ S G P A + P E S G
Sbjct: 76 AAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG 135
Query: 574 N--------ILQAKPTSSPAKGPPQKAGPVAVQVKA----------------EKPMDNSE 609
+ + A P +PA GP + AGP A+ +A KP
Sbjct: 136 SCAPVPAAAAVAAGPEPAPA-GPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGA 194
Query: 610 SSEESSDSA--DSEEAPA-AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 666
+ + +A +S A A A++ PA +P K P T P VG AP
Sbjct: 195 AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK--PAAPGTVIQ---TPPFVGAAAP 249
Query: 667 RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKA 726
+ PA +PA P + + T+ + G A
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPA---------------TLARPPGHPAGPPTAA 294
Query: 727 ASVPVK------GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
+VP GS G AP P GP + S + AAA
Sbjct: 295 PAVPPPAAAQNGGSAGAAPAPA-PAAGGP------------AGVSGQPGPGAAAAAPAPG 341
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTIS-APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV 839
VK K +A P AA+ +A G S A V+ Q SP+ V PP P T
Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPA--PGTPTG 399
Query: 840 LARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAA 899
L +G A T + ++T P+ T IRA
Sbjct: 400 LPKGAA-------GAVTQSLSRT--------------------------PTATTSGIRAT 426
Query: 900 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-----GEAPAAVTSAQV 954
L P +PR P PP P+ Q Q G S++ + A AQ
Sbjct: 427 LTPTVLAPR---LPQPP--QNPTNIQ-NFQLPPGMVLVRSENGQLLMIPQQALAQMQAQA 480
Query: 955 IKPPLIFVDPNRSPAGPAATP----AQAQAASTPRKAR-ASESTARSSSSESEDEDVIPA 1009
P + P PA P + P + QA TP AR + +T S+++ A
Sbjct: 481 HAQPQTTMAPR--PATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSA 538
Query: 1010 TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPAS 1069
T +PG++ +V A A A + R G A + +N
Sbjct: 539 TLQRSPGVQPQLVLGGAAQ---TASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKK 595
Query: 1070 LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1129
+ L LA ++ T+ ++ V V L ++ ++ +L
Sbjct: 596 CKNFLSTLIKLASSGKQS------TETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSP 649
Query: 1130 LPEVQQATK--APESSDDSEDSSDSSSGSEEDGEGPQG----AKSAHTLGPTPSRTETLV 1183
P + K P + DS+ S++ P A +A L + RT
Sbjct: 650 QPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKT 709
Query: 1184 EETAAESSEDDVVAPSQSLLSGYMTPGL-TPANSQASKATPKLDSSPSVSST---LAAKD 1239
T + + V++ +Q G G TP Q L P V+ T + A
Sbjct: 710 AATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALR 769
Query: 1240 DPDGK--------QEAKPQQAAGMLSPKT-GGKEAASGTTPQKSRKPKKGAGNPQASTLA 1290
P + + P Q ++ P G +A S + Q + K P +
Sbjct: 770 QPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFR 829
Query: 1291 LQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS 1350
+I N+ A V L +E +++ T E + R
Sbjct: 830 DDDDI-----------NDVASMAGV------NLSEESARILATNSELV----GTLTRSCK 868
Query: 1351 GDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKR-----DKASGDVKEKKGK 1405
+ + P ++ ++G + G + P+ S S +R +K S ++K
Sbjct: 869 DETFLLQAPLQRRILEIGK-KHGITELHPDVVSYVSHATQQRLQNLVEKISETAQQK--- 924
Query: 1406 GSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKAS 1465
+ KD+ E + ++ K ++ + +K++KD++++E +A K+
Sbjct: 925 ----NFSYKDDDRYEQASDV-------RAQLKFFEQLDQIEKQRKDEQEREILMRAAKSR 973
Query: 1466 TKDSESPSQKKKKKKKKTAEQ 1486
++ E P Q + K+K K +Q
Sbjct: 974 SR-QEDPEQLRLKQKAKEMQQ 993
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 95.5 bits (236), Expect = 3e-19
Identities = 249/1227 (20%), Positives = 410/1227 (33%), Gaps = 166/1227 (13%)
Query: 98 TAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSP 157
TA PR+ S S++ P++ + + G + TG T LLS SP
Sbjct: 525 TAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLS--SP 582
Query: 158 RKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS 217
S T ++ S P + +A + S+ ++S+S + P+
Sbjct: 583 SYSV-----TQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQES----PA 633
Query: 218 VKPAQVKASSVSTKESPA-RKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG 276
V + +T+ES R +P TP A + P++ S
Sbjct: 634 VSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTIS--A 691
Query: 277 SESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVASQTKAG 333
+ + AP G +A LQ +S A P G + + G A +V S T G
Sbjct: 692 ATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVS-TPGG 750
Query: 334 KPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK 393
+ + +S+ S D+ +ASG+T AS+ ++ + A P+ G
Sbjct: 751 PEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGA 810
Query: 394 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453
+G S S S E + PS + ++ + S GA P
Sbjct: 811 SGTT------------PSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIP 858
Query: 454 AP--------PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 505
P P ++ + S + S S +E A AQ +
Sbjct: 859 VSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQ------- 911
Query: 506 VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGE------ 559
+ ++ G + + P TP + ++ + S S G+
Sbjct: 912 -RTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTAL 970
Query: 560 ----VPTAVAPAQEKSLG-----NILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES 610
P V A S G ++ A S+ P P +V P+ +++
Sbjct: 971 ISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDT 1030
Query: 611 SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAG 670
S ES+ + + ++A + +P T T++ ++ V P+ V + + G
Sbjct: 1031 SSESTGHV-TPLPVTSFSSASTGDSTPLPVT-----DTSSASTGHVTPLPVTSLSSASTG 1084
Query: 671 TATS---PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA 727
T SS + T P D+SS S T L VT + S G A
Sbjct: 1085 DTTPLPVTDTSSASTGHATSLPVTDTSSV----STGHTTPLPVTDTSSASTG-----HAT 1135
Query: 728 SVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK 787
S+PV T+ V G T P + S + A+P V +
Sbjct: 1136 SLPV-----TDTSSVSTGHTTPL-------------HVTDASSASTGQATPLPVTSLSSV 1177
Query: 788 TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
+ P +PS+ T A +VT + A + + + ++ P ++
Sbjct: 1178 STGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTI 1237
Query: 848 PSVGKA-------VATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
PS V + A TG ++ S S + L S + L
Sbjct: 1238 PSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPL 1297
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE-APAAVTSAQVIK--- 956
S TP T S+A G +S S S G+ P VT A +
Sbjct: 1298 HVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGH 1357
Query: 957 -PPLIFVDPNRSPAGPA---------------ATPAQAQAASTPRKARAS----ESTARS 996
PL D + + G A TP + S+ A+ T+ +
Sbjct: 1358 TTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSA 1417
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMP----TAHPRIAPKASMAGASSSK-------E 1045
S+ + V A+ T + VT+P T H P + AS+ + +
Sbjct: 1418 STGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTD 1477
Query: 1046 SSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVG 1105
+S +S G P T S + + A PV +S D+
Sbjct: 1478 TSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTM-- 1535
Query: 1106 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDS--------SDSSSGSE 1157
LP TSP S S + T P +S S + +D+SS S+
Sbjct: 1536 PLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASK 1595
Query: 1158 EDG-----EGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAP---SQSLLSGYMTP 1209
D P A + HT P P V +T++ S+ D P + SL +G+ TP
Sbjct: 1596 GDTTPLPVTSPSSASTGHTT-PLP------VTDTSSASTGDTTPLPVTNASSLSTGHATP 1648
Query: 1210 --GLTPANSQASKATPKLDSSPSVSST 1234
+P+++ ATP +S S +ST
Sbjct: 1649 LHVTSPSSASTGHATPLPVTSTSSAST 1675
Score = 85.5 bits (210), Expect = 3e-16
Identities = 255/1210 (21%), Positives = 416/1210 (34%), Gaps = 122/1210 (10%)
Query: 94 AEAETAKATPR-LASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLL 152
+ A T ATP + S +S+ G +P + + A T G++ P P T + +
Sbjct: 1511 SSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAST------GDTTPLPVTDASSVSTG 1564
Query: 153 SGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDV 212
++ SA+T + + A P V++ + S+ T +T
Sbjct: 1565 HTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSS 1624
Query: 213 EGKPSVKPAQV-KASSVSTKES-PARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEES 270
P V ASS+ST + P +P+ G TP + P +
Sbjct: 1625 ASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVT 1684
Query: 271 ESSEEGSESEEEAPAGTRSQVKASEKI-LQVRAASAPAKGT----PGKGATPAPPGKAG- 324
S ++ P S + L V + S+ + G P + A G A
Sbjct: 1685 GLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASP 1744
Query: 325 -----AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV------GA 373
A ++ T P +++SS ++ + TP L + ++ T+++ A
Sbjct: 1745 LLVTDASSASTGQATPLPVTDTSSVSTAHA---TPLPVTGLSSASTDDTTRLPVTDVSSA 1801
Query: 374 ASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREED---------SQSSSEESDSEEEAP 424
++ A P + A G T P + D S +SS + S
Sbjct: 1802 STGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTD 1861
Query: 425 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDS 484
A + +G A + A + + P + + + S S+ +
Sbjct: 1862 ASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSL 1921
Query: 485 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED 544
+L++ + PL P P+S +G P P T ++ V
Sbjct: 1922 PVTSLSSASTGDTTPL---PVTSPSSA--------SSGHTTPL---PVTDASSVPTGHAT 1967
Query: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAGPVAVQVKAE 602
S ++ SS S+ P V A S G+ L TSS + G PV A
Sbjct: 1968 SLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPL-PVTSLSSAS 2026
Query: 603 KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA-PVRV 661
++S ++ ++ P +T+ + + T P + ++AS A P+ V
Sbjct: 2027 TGDTTPLPVTDTSSASTGQDTPLPVTSLSS---VSTGDTTPLPVTSPSSASTGHATPLLV 2083
Query: 662 GTQAPRKAGTATS---PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSV 718
+ G ATS SS + T D+SS D+ T L VT + S
Sbjct: 2084 TDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDT----TPLPVTSPSSAST 2139
Query: 719 GKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
G + S+ G A LP T T + S + S + A+P
Sbjct: 2140 GDTTPLPVTDT---SSVSTGHATSLP----VTDTSSASTGHATSLPVTDTSSASTGHATP 2192
Query: 779 AQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV--TAAAQAKQRSPSKVKP-PVRNPQ 835
V + + +A P +PS+ T A +V T++A Q +P V +
Sbjct: 2193 LPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTG 2252
Query: 836 NSTVLARGPASVPSVGKA----VATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSG 891
++T L AS S G A V + + TG + S S A L S
Sbjct: 2253 DTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASS 2312
Query: 892 KTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE-APAAVT 950
+ L S TP T PS+A G + S S G+ P VT
Sbjct: 2313 ASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVT 2372
Query: 951 SAQVIK----PPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS-SSSESEDED 1005
S+ PL D + + G TP S+ A+ SS+ + D
Sbjct: 2373 SSSSASSGHTTPLPVTDASSASTGD-TTPLPVTDTSSASTGHATHLPVTGLSSASTGDTT 2431
Query: 1006 VIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS-------SKESSRISDGKKQE-- 1056
+P TNV + T H P S + AS+ ++S +S G
Sbjct: 2432 RLPV---------TNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLL 2482
Query: 1057 -GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQST 1115
A+ VS + LP+T + A PV T +S D+ LP T+ S
Sbjct: 2483 VTDASSVSTGDTTRLPVTSPS---SASTGHTTPLPVTDTPSASTGDTT--PLPVTNASSL 2537
Query: 1116 SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSD------SSSGSEEDGEGPQGAKSA 1169
S + + + P AT P + + + +S+ S G+ +
Sbjct: 2538 STRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTD 2597
Query: 1170 HTLGPTPSRTETLVEETAAESSEDDVVAP---SQSLLSGYMTPGLTPANSQAS--KATPK 1224
T T V +T++ S+ D P + S +G+ TP S S ATP
Sbjct: 2598 TYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPL 2657
Query: 1225 LDSSPSVSST 1234
+SPS +ST
Sbjct: 2658 HVTSPSSAST 2667
Score = 74.7 bits (182), Expect = 6e-13
Identities = 254/1229 (20%), Positives = 409/1229 (33%), Gaps = 150/1229 (12%)
Query: 70 ALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADL-PSSMKEKAKAE 128
+L + T + P+ +++S A T +ATP ++ SSV D P + + + A
Sbjct: 2773 SLSSVSTGDTTPLPVTDTSS------ASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSAS 2826
Query: 129 TEKA----------GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGS 178
T A TG++ P P T + A+ +G + +++ ++ T S
Sbjct: 2827 TGHATSLPVTDTSSASTGHATPLPDTDTSSAS--TGHATLLPVTDTSSASIGHAT----S 2880
Query: 179 VPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA 238
+P ++ +S G A + TS SS T G + P +S+ + +P
Sbjct: 2881 LPVTDTSS----ISTGHA-TPLHVTSPSSAST---GHATPLPVTDTSSASTGHANPLHVT 2932
Query: 239 APAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKI- 297
+P+ G TP P ++ S+ G + P + S V +
Sbjct: 2933 SPSSASTGHATPL--------------PVTDTSSASTGHATP--LPVTSLSSVSTGDTTP 2976
Query: 298 LQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAK 357
L V + S+ + G TP P + ++ P + S+S + T +
Sbjct: 2977 LPVTSPSSASTGH----TTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSS 3032
Query: 358 ALL-QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV----AKAQAGKREEDSQS 412
A QA TS ++ P + A G P + + A G+ +
Sbjct: 3033 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVT 3092
Query: 413 SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
S + + P A A S P ++ ++
Sbjct: 3093 SLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTS 3152
Query: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ-VKPASTMGMG---------PLGKGAG 522
+S S D L + V +P V AS+ G P G
Sbjct: 3153 LPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTG 3212
Query: 523 PVPPGKV--------GPATPSAQVGKWEEDSESSS-----EESSDSSDGEVPTAVAPAQE 569
P V G ATP G + ++ + SS S+ P V
Sbjct: 3213 DTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSS 3272
Query: 570 KSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTA 629
S G+ + P +SP+ A P+ V + ++ +S S+ S +
Sbjct: 3273 VSTGDTMPL-PVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPV 3331
Query: 630 AQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAG-TATSPA-GSSPAVAG-GT 686
A T ++ ++ P+ V + G T+T P G+S A G T
Sbjct: 3332 TDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHAT 3391
Query: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
P D+SS S T L VT + S G + S G A LP
Sbjct: 3392 PLPVTDTSSV----STGHATPLPVTSLSSVSTGDTTPLPVTDA---SSASTGQATPLP-- 3442
Query: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
VT + SS D+ + A +SV A P + ++ G
Sbjct: 3443 ----VTSL---------SSVSTGDTTPLLVTDA---SSVSTGHATPLPVTDTSSASTGDT 3486
Query: 807 SAPGKVVTAAAQAKQRSPSKVKPPVR-NPQNSTVLARGPASVPSVGKA----VATAAQAQ 861
+ T++A Q +P V + ++T L AS S G A V + A
Sbjct: 3487 TRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSAS 3546
Query: 862 TGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGP 921
TG ++ S S +A L PS + L S TP T P
Sbjct: 3547 TGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSP 3606
Query: 922 SAAQAGKQDDSGSSSEESDSDGEA-PAAVTSAQVIK----PPLIFVDPNRSPAGPAATPA 976
S+A G +S S S G A P VT A + PL D + + G TP
Sbjct: 3607 SSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGD-TTPL 3665
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
S+ +A+ S SS S T TP T+ + T H P
Sbjct: 3666 PVTDTSSASTGQATPLPVTSLSSVS--------TGDTTPLPVTDASSASTGHATPLPVTI 3717
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1096
S +S G P T S + T + L+ ++ P+ T
Sbjct: 3718 ---------PSSVSTGDTMPLPVTSPSSASTGH--ATPLPVTGLSSASTGDTTPLPVTDT 3766
Query: 1097 SSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS--- 1153
SS LP T S S + AT P +S S + D++
Sbjct: 3767 SSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLP 3826
Query: 1154 ---SGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAP---SQSLLSGYM 1207
+ S G ++ + T T V +T++ S+ P + S+ +G+
Sbjct: 3827 VTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHA 3886
Query: 1208 T--PGLTPANSQASKATPKLDSSPSVSST 1234
T P +P+++ ATP +S S +ST
Sbjct: 3887 TPLPVTSPSSASTGHATPVPVTSTSSAST 3915
Score = 68.2 bits (165), Expect = 6e-11
Identities = 267/1281 (20%), Positives = 418/1281 (32%), Gaps = 166/1281 (12%)
Query: 92 EEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANL 151
+ + A T ATP ++ SSV D + + TG++ P P T +
Sbjct: 2949 DTSSASTGHATPLPVTSLSSVSTGDTTP-----LPVTSPSSASTGHTTPLPVTDTS---- 2999
Query: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
S + + +A P +T+ S T + +P ++ S GQA + SS D
Sbjct: 3000 -SASTGQATALPVTSTSSAS-TGDTTPLPVTDTSS----ASTGQATPLPVTSLSSVSTGD 3053
Query: 212 VEGKPSVKPAQVK-----------ASSVSTKES-PARKAAPAPGKVGDVTP-QVKGGALP 258
P P+ ASS ST ++ P + + GD TP V +
Sbjct: 3054 TTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSA 3113
Query: 259 PAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318
A SS ++ T S L V S+ + G TP
Sbjct: 3114 STGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGD----TTPL 3169
Query: 319 PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV------G 372
+ +V++ D+ S+S + TP + ++G T+ V
Sbjct: 3170 LVTETSSVSTGHATPLLVTDASSAS-----TGHATPLHVTSPSSASTGDTTPVPVTDTSS 3224
Query: 373 AASAPAKESPRKGAAPAPPGKTGPA----VAKAQAGKREEDSQSSSEESDSEEEAPAQAK 428
++ A P G + A G T ++ A G+ +++ + + P
Sbjct: 3225 VSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVT 3284
Query: 429 PSGKAPQVRAASAPAKESPRKG---AAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 485
A A P + A P P T A+ D+ S+S +
Sbjct: 3285 SPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTP 3344
Query: 486 REALAAMNAA--QVKPLGKS--PQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW 541
+ +A+ PL + T + G + P T ++ V
Sbjct: 3345 LPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTG 3404
Query: 542 EEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKG---PPQKAGPVA 596
+ SS S+ P V A S G L SS + G P +
Sbjct: 3405 HATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASS 3464
Query: 597 VQVKAEKPMDNSESSEESSDSADSEEAPAAMTA-AQAKPALKIPQTKACPKKTNTTASAK 655
V P+ +++S S+ + D+ P T+ A A +P T T T
Sbjct: 3465 VSTGHATPLPVTDTS--SASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTT--- 3519
Query: 656 VAPVRVGTQAPRKAGTATS--PAGSSPAVAGGTQR-PAEDSSSSEESDSEEEKTGLAVTV 712
P+ V + G AT +S A G T R P D+SS+ S + T L VT+
Sbjct: 3520 --PLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSA----STGQATPLPVTI 3573
Query: 713 GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSE 772
+ S G +PV + T V P + +S + +
Sbjct: 3574 PSSSSSGH-----TTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTG 3628
Query: 773 EAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVR 832
A +SV A P + ++ G + T++A Q +P V
Sbjct: 3629 HATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSS 3688
Query: 833 -NPQNSTVLARGPASVPSVGKA----VATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV 887
+ ++T L AS S G A V + TG + S S A L
Sbjct: 3689 VSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVT 3748
Query: 888 KPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEA-P 946
S + L S TP T S+A + S S G A P
Sbjct: 3749 GLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATP 3808
Query: 947 AAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDV 1006
VTS D P ++ + A S P +R+S ST ++ D
Sbjct: 3809 LPVTSTSSASTG----DTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSS 3864
Query: 1007 IPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKN 1066
+ +T TP T+ ++ T H P S + AS+ G P T S +
Sbjct: 3865 V-STGHATPLPVTSTSSVSTGHATPLPVTSPSSAST---------GHATPVPVTSTSSAS 3914
Query: 1067 PAS---LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQS--------- 1114
LP+T A+ ++ P+ T PSS TLP T S
Sbjct: 3915 TGDTTPLPVTNAS-----SLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPL 3969
Query: 1115 --TSVQAKGTNKLRKPKLPEVQ-----QATKAPESSDDSEDSSDSSSGSEEDGEGPQGAK 1167
TS+ + T + + QAT P +S S + D++ P A
Sbjct: 3970 PLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTI---PSSAS 4026
Query: 1168 SAHTLG---------PTPSRTETLVEETAAESSEDDVVAP---SQSLLSGYMTPGLTPAN 1215
S HT T T V T++ S+ D P + S +G+ TP
Sbjct: 4027 SGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDT 4086
Query: 1216 SQAS------------------KATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLS 1257
S AS ATP SS + +ST+++ D P + GM +
Sbjct: 4087 SSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSS-DSP------LKMETPGMTT 4139
Query: 1258 PK---TGGKEAASGTTPQKSR 1275
P GG+ A+ P S+
Sbjct: 4140 PSLKTDGGRRTATSPPPTTSQ 4160
Score = 55.8 bits (133), Expect = 3e-07
Identities = 179/888 (20%), Positives = 286/888 (32%), Gaps = 123/888 (13%)
Query: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
M + LG + + A T P+ A + G+ G + ++ W +S ++
Sbjct: 140 MTTSTDSTLGNTEETSTAGTESSTPV-TSAVSITAGQEGQSRTTS----WR----TSIQD 190
Query: 552 SSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESS 611
+S SS + +E S + L + TS+P+ P V K S S
Sbjct: 191 TSASSQNHWTRSTQTTRE-SQTSTLTHRTTSTPSFSPSVHNVTGTVSQKT------SPSG 243
Query: 612 EESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGT 671
E ++ S S + MT+ + T P +T++ PV A
Sbjct: 244 ETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSV------PVTGSLMPVTSAAL 297
Query: 672 AT-SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVP 730
T P G SPA T + S E T V Q ++ V ++V
Sbjct: 298 VTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETT----RVSQINTLNTLTPVTTSTVL 353
Query: 731 VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQA 790
P P+ T QE S E + S + ++ V + V +
Sbjct: 354 SS-----------PSGFNPSGTV----SQETFPSGETTTSSPSSVSNTFLVTSKVFRMPT 398
Query: 791 KANPAAARAP----SAKGTISA-PGKVVT-------AAAQAKQRSPSKVKPPVRNPQNST 838
+ S GTISA KV T + A + P K+ Q+
Sbjct: 399 SRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEG 458
Query: 839 VLARG-----PASVPSVGKAVATAAQAQTGPEEDSGS-------SEEESDSEEEAETLAQ 886
G + P V + + T + T P S +E S S A L
Sbjct: 459 AETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVT 518
Query: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTPPGK---------TGPSAAQAGKQDDSGSSSE 937
PS T A P P K +A PG+ T P AG Q ++
Sbjct: 519 GNPSTGT----AGTIP--RVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQW---TQ 569
Query: 938 ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP-------------------------AGPA 972
E+ + GEA + S V + P+ SP P
Sbjct: 570 ETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQ 629
Query: 973 ATPAQAQAASTPRKARASES-TARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI 1031
+PA +Q T ES T RS S ++ + V T + +P P I
Sbjct: 630 ESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTI 689
Query: 1032 APKASMAGASSSK-ESSRISDGKKQEGPATQVSKKNPA---SLPLTQAALKVLAQKASEA 1087
+ + A A + +++ Q P++ + P+ SL T A + ++
Sbjct: 690 SAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPG 749
Query: 1088 QPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLP---EVQQATKAPESSD 1144
P T S+ + Q+ S +A G + +P T P SS
Sbjct: 750 GPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSG 809
Query: 1145 DSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLS 1204
S + S G GE + + + T T L+ +A+ + + S++
Sbjct: 810 ASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVP 869
Query: 1205 GYMTPGLTPANSQASKATPKLDSSPSVS-STLAAKDDPDGKQEAKPQQAAGMLSPKTGGK 1263
G P L+ A++ +SPS S AA Q + + + +S +
Sbjct: 870 GTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQAT 929
Query: 1264 EAASGTTPQKSRKPKKGAGNPQASTLALQ-----SNITQCLLGQPWPL 1306
+ S P G +PQ T L T L+ PL
Sbjct: 930 DTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPL 977
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 95.1 bits (235), Expect = 4e-19
Identities = 246/1340 (18%), Positives = 453/1340 (33%), Gaps = 147/1340 (10%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
+T +S G++ + + + ++ T + + P P +T +SG
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE---------- 64
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226
++ T GS ++A G +A A S + +++ S+ T V +
Sbjct: 65 ---ITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
S +T S G T V E + +S GSE AG
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 287 TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
+ + TP+ G S T + S + SE +
Sbjct: 182 SET-------------------------ITPSTAGSETTTVS-TAGSETTTVSTTGSETT 215
Query: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406
+ S + A + K S G+ + + AA +T A
Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT------- 268
Query: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
EDS++++ + E A +G P + + G+ GP +V
Sbjct: 269 -EDSKTTTASTTGFETTAAST--TGSEPTMAST---------MGSETTMASTIGPETTKV 316
Query: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
E + ++ S++ R + V G + AS MG
Sbjct: 317 STASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTASIMGS------------ 361
Query: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSSPA 585
+T S + S SE ++ S++G E T E + +I ++ T++
Sbjct: 362 ---ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCT 418
Query: 586 KGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAPAAMTAAQAKPALKIPQT 641
+G A V + SE S+ +S + S E T A K T
Sbjct: 419 EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478
Query: 642 KACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES-- 699
+T T ++ + V T +T + ++ A G++ + SE +
Sbjct: 479 TG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV 536
Query: 700 ------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
+ TGL T + S + A + G GT G T
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA--STAGSETT 594
Query: 753 QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKV 812
V E++ +S +DSE +AS +T+ T + A+ S T+S
Sbjct: 595 TVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652
Query: 813 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GKAVATAAQAQTGPEEDSG 869
T + + + +TV A G + S G + ++T +G
Sbjct: 653 TTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709
Query: 870 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
S + +E T A + S +T + + +G+ T TG A
Sbjct: 710 SETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768
Query: 930 DDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS 982
GS + + + G V++A K +F + N + T ++ S
Sbjct: 769 SSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-NSETTIASTTASETTTVS 826
Query: 983 TPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS 1042
T STA S ++ + + T T G T + ++ + + A
Sbjct: 827 TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESS------ETTTATTIG 880
Query: 1043 SKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKASEAQPPVARTQPSSGVD 1101
S+ ++ ++G + +T+ S+ AS ++ + + + A + T +S
Sbjct: 881 SETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940
Query: 1102 SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGE 1161
S + T+ T ++ +V A+G+ + + T A S+ SE ++ S++GSE
Sbjct: 941 SELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STAGSETTTVSTAGSETTTA 996
Query: 1162 GPQGAKSAHTLGPTPSRTETL------VEETAAESSEDDVVAPSQSLLSG-YMTPGLTPA 1214
+G+++ T+ T S T T+ T+ E SE V + S + Y T T
Sbjct: 997 SIEGSETT-TVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1215 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1274
S T + ++ S ++T + D + +G + T G E + S
Sbjct: 1056 TSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTTTASTAGSETTT-VYITGS 1111
Query: 1275 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT- 1333
+ +A+T++ S+ T + + + V T + E + +
Sbjct: 1112 KTTTASTEGSEATTVSTTSSET---------TTASTTGSEMTTVFTTVSETTTVSTIGSE 1162
Query: 1334 TKESSRKGWESRKRKLSGDQ-PAARTPRSKKKKKLGAG-EGGEASVSPEKTSTTSKGKAK 1391
SS G E+ G + A T S+ AG E AS + +T+T S ++
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE 1222
Query: 1392 RDKASGDVKEKKGKGSLGSQ 1411
+ A E S GS+
Sbjct: 1223 TNTACTTGSETSTPSSAGSE 1242
Score = 89.0 bits (219), Expect = 3e-17
Identities = 223/1228 (18%), Positives = 408/1228 (33%), Gaps = 112/1228 (9%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E + + ++ + +
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 328
Query: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
AG + S + G + A + S ST + + A + + T
Sbjct: 329 AGSETIRASTVGSETTTVSTTGSETT-TASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 253 KGGALPPAKRAKKPE------EESESSEEGSESEEEAPAGTR--SQVKASEKILQVRAAS 304
G+ E +SE++ +E E T AS + ++ AS
Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAS 447
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
T + S+TK SE+++ ++ E T A
Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAY-TTGSETTTASNTGLETTTVFTIGSDTTTA 506
Query: 365 SGKTSQVGAASAPAKES---PRKGAAPAPPGKTG------------PAVAKAQAGKREED 409
S + S+ A SA E +G+ TG + +
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
S + +E + E S + S E+ A + ++
Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA 626
Query: 470 K--QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV---KPASTMGMGPLGKGAGPV 524
E + +S+E S++ + V G + + + T + G
Sbjct: 627 STTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686
Query: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSS 583
G G T S + + S + SE ++ S++G E+ TA E + + ++ T++
Sbjct: 687 TEGS-GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
+G + A +E ++ SSE + S E A T + +K
Sbjct: 746 STEGSETTS---ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSP---AGSSPAVAGGTQRPAEDSSSSEESD 700
T + + + T AG+ T P AGS T+ ++S+E S+
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 701 -----SEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS-----LGQGTAPVLPGKTGPT 750
+E +T A T+G + + + +GS +G+ TG
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 751 VTQVKAEKQEDSESSEEESD--------SEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
T E E + +S E S+ SE S +T+ T A+ A S
Sbjct: 923 TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982
Query: 803 KGTISAPGKVVTAAA------QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA- 855
T+S G T A+ + S+ +T+ + + +V A +
Sbjct: 983 TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE 1042
Query: 856 TAAQAQTGPEEDSGS---SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 912
T A TG E + S SE + S +ET +T + + + + G+
Sbjct: 1043 TTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSE 1102
Query: 913 PTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
T TG A + ++ + S+ + S + S G
Sbjct: 1103 TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162
Query: 973 ATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 1032
AT + A + + T +S++ SE T T G T T TA
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSE------TTTASTAGSET--TTASTA----G 1210
Query: 1033 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1092
+ + A S S+ ++ + G + P++ S+ N A + ++ + A A
Sbjct: 1211 SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTG 1270
Query: 1093 RTQPSSGVDSAVGTLPATSPQSTS-VQAKGTNKLRKP--------------KLPEVQQAT 1137
+ + ++ T +T+ ST+ V K T+ +P +L T
Sbjct: 1271 SETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVT 1330
Query: 1138 KAPESSDDSEDSSD-------SSSGSEEDGEGPQGAKSAH----TLGPTPSRTETLVEET 1186
AP + +S ++SG G SAH T G T T + +ET
Sbjct: 1331 MAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQET 1390
Query: 1187 AAESSEDDVVAPSQSLL-----SGYMTP 1209
S + V+ S + SGY+ P
Sbjct: 1391 GPVSMGTNTVSMSHTPTNVIKPSGYLQP 1418
Score = 61.6 bits (148), Expect = 5e-09
Identities = 151/801 (18%), Positives = 263/801 (32%), Gaps = 72/801 (8%)
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 698
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 819 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 870
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 871 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1096
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1097 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1155
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1156 SEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1215
SE +G+++ T+ T S T T V T E++ + +S T T +
Sbjct: 521 SEMTTVSTEGSENT-TVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTTD 576
Query: 1216 SQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSR 1275
S T ++ S ++T++ D + + S T G E + +T
Sbjct: 577 STEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSET 633
Query: 1276 KPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTK 1335
G+ + S T + +T E V T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATGS 681
Query: 1336 ES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGKA 1390
E+ S +G + ++G + + + + + EG E AS++ +T+T S +
Sbjct: 682 ETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740
Query: 1391 KRDKASGDVKEKKGKGSLGSQ 1411
+ AS + E + GS+
Sbjct: 741 ETTTASTEGSETTSASTTGSE 761
Score = 45.8 bits (107), Expect = 3e-04
Identities = 57/336 (16%), Positives = 115/336 (34%), Gaps = 11/336 (3%)
Query: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
E + + T S+ + S E A E ++ T +++T S + S
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT-VSTTGSETITVSAEGSETTTVT 967
Query: 127 ---AETEKAGKTGNSMPHPATG--KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPA 181
+ET A G+ +T +T + G + + TT VS T E ++ +
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
+ + +AG ++ T S + T EG + + + + + + +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087
Query: 242 PGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ 299
G T G +K +E SE + S + T S + +
Sbjct: 1088 TSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVF 1147
Query: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
+ T G AT + + A + T+ + S + SE ++ S T ++
Sbjct: 1148 TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS---TAGSETT 1204
Query: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
+ A +T+ + + + G+ + P G
Sbjct: 1205 TASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1240
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 95.1 bits (235), Expect = 4e-19
Identities = 246/1340 (18%), Positives = 453/1340 (33%), Gaps = 147/1340 (10%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
+T +S G++ + + + ++ T + + P P +T +SG
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE---------- 64
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226
++ T GS ++A G +A A S + +++ S+ T V +
Sbjct: 65 ---ITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
S +T S G T V E + +S GSE AG
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 287 TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
+ + TP+ G S T + S + SE +
Sbjct: 182 SET-------------------------ITPSTAGSETTTVS-TAGSETTTVSTTGSETT 215
Query: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406
+ S + A + K S G+ + + AA +T A
Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT------- 268
Query: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
EDS++++ + E A +G P + + G+ GP +V
Sbjct: 269 -EDSKTTTASTTGFETTAAST--TGSEPTMAST---------MGSETTMASTIGPETTKV 316
Query: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
E + ++ S++ R + V G + AS MG
Sbjct: 317 STASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTASIMGS------------ 361
Query: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSSPA 585
+T S + S SE ++ S++G E T E + +I ++ T++
Sbjct: 362 ---ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCT 418
Query: 586 KGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAPAAMTAAQAKPALKIPQT 641
+G A V + SE S+ +S + S E T A K T
Sbjct: 419 EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478
Query: 642 KACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES-- 699
+T T ++ + V T +T + ++ A G++ + SE +
Sbjct: 479 TG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV 536
Query: 700 ------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
+ TGL T + S + A + G GT G T
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA--STAGSETT 594
Query: 753 QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKV 812
V E++ +S +DSE +AS +T+ T + A+ S T+S
Sbjct: 595 TVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652
Query: 813 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GKAVATAAQAQTGPEEDSG 869
T + + + +TV A G + S G + ++T +G
Sbjct: 653 TTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709
Query: 870 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
S + +E T A + S +T + + +G+ T TG A
Sbjct: 710 SETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768
Query: 930 DDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS 982
GS + + + G V++A K +F + N + T ++ S
Sbjct: 769 SSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-NSETTIASTTASETTTVS 826
Query: 983 TPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS 1042
T STA S ++ + + T T G T + ++ + + A
Sbjct: 827 TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESS------ETTTATTIG 880
Query: 1043 SKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKASEAQPPVARTQPSSGVD 1101
S+ ++ ++G + +T+ S+ AS ++ + + + A + T +S
Sbjct: 881 SETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940
Query: 1102 SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGE 1161
S + T+ T ++ +V A+G+ + + T A S+ SE ++ S++GSE
Sbjct: 941 SELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STAGSETTTVSTAGSETTTA 996
Query: 1162 GPQGAKSAHTLGPTPSRTETL------VEETAAESSEDDVVAPSQSLLSG-YMTPGLTPA 1214
+G+++ T+ T S T T+ T+ E SE V + S + Y T T
Sbjct: 997 SIEGSETT-TVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1215 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1274
S T + ++ S ++T + D + +G + T G E + S
Sbjct: 1056 TSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTTTASTAGSETTT-VYITGS 1111
Query: 1275 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT- 1333
+ +A+T++ S+ T + + + V T + E + +
Sbjct: 1112 KTTTASTEGSEATTVSTTSSET---------TTASTTGSEMTTVFTTVSETTTVSTIGSE 1162
Query: 1334 TKESSRKGWESRKRKLSGDQ-PAARTPRSKKKKKLGAG-EGGEASVSPEKTSTTSKGKAK 1391
SS G E+ G + A T S+ AG E AS + +T+T S ++
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE 1222
Query: 1392 RDKASGDVKEKKGKGSLGSQ 1411
+ A E S GS+
Sbjct: 1223 TNTACTTGSETSTPSSAGSE 1242
Score = 89.0 bits (219), Expect = 3e-17
Identities = 223/1228 (18%), Positives = 408/1228 (33%), Gaps = 112/1228 (9%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E + + ++ + +
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 328
Query: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
AG + S + G + A + S ST + + A + + T
Sbjct: 329 AGSETIRASTVGSETTTVSTTGSETT-TASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 253 KGGALPPAKRAKKPE------EESESSEEGSESEEEAPAGTR--SQVKASEKILQVRAAS 304
G+ E +SE++ +E E T AS + ++ AS
Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAS 447
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
T + S+TK SE+++ ++ E T A
Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAY-TTGSETTTASNTGLETTTVFTIGSDTTTA 506
Query: 365 SGKTSQVGAASAPAKES---PRKGAAPAPPGKTG------------PAVAKAQAGKREED 409
S + S+ A SA E +G+ TG + +
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
S + +E + E S + S E+ A + ++
Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA 626
Query: 470 K--QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV---KPASTMGMGPLGKGAGPV 524
E + +S+E S++ + V G + + + T + G
Sbjct: 627 STTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686
Query: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSS 583
G G T S + + S + SE ++ S++G E+ TA E + + ++ T++
Sbjct: 687 TEGS-GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
+G + A +E ++ SSE + S E A T + +K
Sbjct: 746 STEGSETTS---ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSP---AGSSPAVAGGTQRPAEDSSSSEESD 700
T + + + T AG+ T P AGS T+ ++S+E S+
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 701 -----SEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS-----LGQGTAPVLPGKTGPT 750
+E +T A T+G + + + +GS +G+ TG
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 751 VTQVKAEKQEDSESSEEESD--------SEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
T E E + +S E S+ SE S +T+ T A+ A S
Sbjct: 923 TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982
Query: 803 KGTISAPGKVVTAAA------QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA- 855
T+S G T A+ + S+ +T+ + + +V A +
Sbjct: 983 TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE 1042
Query: 856 TAAQAQTGPEEDSGS---SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 912
T A TG E + S SE + S +ET +T + + + + G+
Sbjct: 1043 TTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSE 1102
Query: 913 PTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
T TG A + ++ + S+ + S + S G
Sbjct: 1103 TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162
Query: 973 ATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 1032
AT + A + + T +S++ SE T T G T T TA
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSE------TTTASTAGSET--TTASTA----G 1210
Query: 1033 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1092
+ + A S S+ ++ + G + P++ S+ N A + ++ + A A
Sbjct: 1211 SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTG 1270
Query: 1093 RTQPSSGVDSAVGTLPATSPQSTS-VQAKGTNKLRKP--------------KLPEVQQAT 1137
+ + ++ T +T+ ST+ V K T+ +P +L T
Sbjct: 1271 SETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVT 1330
Query: 1138 KAPESSDDSEDSSD-------SSSGSEEDGEGPQGAKSAH----TLGPTPSRTETLVEET 1186
AP + +S ++SG G SAH T G T T + +ET
Sbjct: 1331 MAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQET 1390
Query: 1187 AAESSEDDVVAPSQSLL-----SGYMTP 1209
S + V+ S + SGY+ P
Sbjct: 1391 GPVSMGTNTVSMSHTPTNVIKPSGYLQP 1418
Score = 61.6 bits (148), Expect = 5e-09
Identities = 151/801 (18%), Positives = 263/801 (32%), Gaps = 72/801 (8%)
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 698
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 819 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 870
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 871 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1096
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1097 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1155
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1156 SEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1215
SE +G+++ T+ T S T T V T E++ + +S T T +
Sbjct: 521 SEMTTVSTEGSENT-TVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTTD 576
Query: 1216 SQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSR 1275
S T ++ S ++T++ D + + S T G E + +T
Sbjct: 577 STEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSET 633
Query: 1276 KPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTK 1335
G+ + S T + +T E V T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATGS 681
Query: 1336 ES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGKA 1390
E+ S +G + ++G + + + + + EG E AS++ +T+T S +
Sbjct: 682 ETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740
Query: 1391 KRDKASGDVKEKKGKGSLGSQ 1411
+ AS + E + GS+
Sbjct: 741 ETTTASTEGSETTSASTTGSE 761
Score = 45.8 bits (107), Expect = 3e-04
Identities = 57/336 (16%), Positives = 115/336 (34%), Gaps = 11/336 (3%)
Query: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
E + + T S+ + S E A E ++ T +++T S + S
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT-VSTTGSETITVSAEGSETTTVT 967
Query: 127 ---AETEKAGKTGNSMPHPATG--KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPA 181
+ET A G+ +T +T + G + + TT VS T E ++ +
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
+ + +AG ++ T S + T EG + + + + + + +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087
Query: 242 PGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ 299
G T G +K +E SE + S + T S + +
Sbjct: 1088 TSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVF 1147
Query: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
+ T G AT + + A + T+ + S + SE ++ S T ++
Sbjct: 1148 TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS---TAGSETT 1204
Query: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
+ A +T+ + + + G+ + P G
Sbjct: 1205 TASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1240
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 95.1 bits (235), Expect = 4e-19
Identities = 246/1340 (18%), Positives = 453/1340 (33%), Gaps = 147/1340 (10%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
+T +S G++ + + + ++ T + + P P +T +SG
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE---------- 64
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226
++ T GS ++A G +A A S + +++ S+ T V +
Sbjct: 65 ---ITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
S +T S G T V E + +S GSE AG
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 287 TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
+ + TP+ G S T + S + SE +
Sbjct: 182 SET-------------------------ITPSTAGSETTTVS-TAGSETTTVSTTGSETT 215
Query: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406
+ S + A + K S G+ + + AA +T A
Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT------- 268
Query: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
EDS++++ + E A +G P + + G+ GP +V
Sbjct: 269 -EDSKTTTASTTGFETTAAST--TGSEPTMAST---------MGSETTMASTIGPETTKV 316
Query: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
E + ++ S++ R + V G + AS MG
Sbjct: 317 STASSEVTTVFAA-GSETIRASTVGSETTTVSTTGS--ETTTASIMGS------------ 361
Query: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSSPA 585
+T S + S SE ++ S++G E T E + +I ++ T++
Sbjct: 362 ---ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCT 418
Query: 586 KGPPQKAGPVAVQVKAEKPMDNSE----SSEESSDSADSEEAPAAMTAAQAKPALKIPQT 641
+G A V + SE S+ +S + S E T A K T
Sbjct: 419 EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478
Query: 642 KACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES-- 699
+T T ++ + V T +T + ++ A G++ + SE +
Sbjct: 479 TG--SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV 536
Query: 700 ------DSEEEKTGLAVTVGQAK-SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
+ TGL T + S + A + G GT G T
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA--STAGSETT 594
Query: 753 QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKV 812
V E++ +S +DSE +AS +T+ T + A+ S T+S
Sbjct: 595 TVSTADSENTTAS--TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652
Query: 813 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV---GKAVATAAQAQTGPEEDSG 869
T + + + +TV A G + S G + ++T +G
Sbjct: 653 TTMVSTT---GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709
Query: 870 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
S + +E T A + S +T + + +G+ T TG A
Sbjct: 710 SETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768
Query: 930 DDS-------GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAAS 982
GS + + + G V++A K +F + N + T ++ S
Sbjct: 769 SSETTMASIMGSETTMASTIGSETTKVSTAS-SKMTTVFTE-NSETTIASTTASETTTVS 826
Query: 983 TPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS 1042
T STA S ++ + + T T G T + ++ + + A
Sbjct: 827 TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESS------ETTTATTIG 880
Query: 1043 SKESSRISDGKKQEGPATQVSKKNPASLPLTQ-AALKVLAQKASEAQPPVARTQPSSGVD 1101
S+ ++ ++G + +T+ S+ AS ++ + + + A + T +S
Sbjct: 881 SETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940
Query: 1102 SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGE 1161
S + T+ T ++ +V A+G+ + + T A S+ SE ++ S++GSE
Sbjct: 941 SELTTVSTTGSETITVSAEGSETTTVTTMG--SETTTA--STAGSETTTVSTAGSETTTA 996
Query: 1162 GPQGAKSAHTLGPTPSRTETL------VEETAAESSEDDVVAPSQSLLSG-YMTPGLTPA 1214
+G+++ T+ T S T T+ T+ E SE V + S + Y T T
Sbjct: 997 SIEGSETT-TVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1215 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1274
S T + ++ S ++T + D + +G + T G E + S
Sbjct: 1056 TSTEGSETTTVSTTGSETTTAST---ADLETTTVSTSGSGTTTASTAGSETTT-VYITGS 1111
Query: 1275 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT- 1333
+ +A+T++ S+ T + + + V T + E + +
Sbjct: 1112 KTTTASTEGSEATTVSTTSSET---------TTASTTGSEMTTVFTTVSETTTVSTIGSE 1162
Query: 1334 TKESSRKGWESRKRKLSGDQ-PAARTPRSKKKKKLGAG-EGGEASVSPEKTSTTSKGKAK 1391
SS G E+ G + A T S+ AG E AS + +T+T S ++
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE 1222
Query: 1392 RDKASGDVKEKKGKGSLGSQ 1411
+ A E S GS+
Sbjct: 1223 TNTACTTGSETSTPSSAGSE 1242
Score = 89.0 bits (219), Expect = 3e-17
Identities = 223/1228 (18%), Positives = 408/1228 (33%), Gaps = 112/1228 (9%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E + + ++ + +
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 328
Query: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
AG + S + G + A + S ST + + A + + T
Sbjct: 329 AGSETIRASTVGSETTTVSTTGSETT-TASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 253 KGGALPPAKRAKKPE------EESESSEEGSESEEEAPAGTR--SQVKASEKILQVRAAS 304
G+ E +SE++ +E E T AS + ++ AS
Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAS 447
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
T + S+TK SE+++ ++ E T A
Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAY-TTGSETTTASNTGLETTTVFTIGSDTTTA 506
Query: 365 SGKTSQVGAASAPAKES---PRKGAAPAPPGKTG------------PAVAKAQAGKREED 409
S + S+ A SA E +G+ TG + +
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
S + +E + E S + S E+ A + ++
Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA 626
Query: 470 K--QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV---KPASTMGMGPLGKGAGPV 524
E + +S+E S++ + V G + + + T + G
Sbjct: 627 STTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686
Query: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSS 583
G G T S + + S + SE ++ S++G E+ TA E + + ++ T++
Sbjct: 687 TEGS-GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
+G + A +E ++ SSE + S E A T + +K
Sbjct: 746 STEGSETTS---ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSP---AGSSPAVAGGTQRPAEDSSSSEESD 700
T + + + T AG+ T P AGS T+ ++S+E S+
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 701 -----SEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS-----LGQGTAPVLPGKTGPT 750
+E +T A T+G + + + +GS +G+ TG
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 751 VTQVKAEKQEDSESSEEESD--------SEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
T E E + +S E S+ SE S +T+ T A+ A S
Sbjct: 923 TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982
Query: 803 KGTISAPGKVVTAAA------QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA- 855
T+S G T A+ + S+ +T+ + + +V A +
Sbjct: 983 TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE 1042
Query: 856 TAAQAQTGPEEDSGS---SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA 912
T A TG E + S SE + S +ET +T + + + + G+
Sbjct: 1043 TTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSE 1102
Query: 913 PTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
T TG A + ++ + S+ + S + S G
Sbjct: 1103 TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162
Query: 973 ATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 1032
AT + A + + T +S++ SE T T G T T TA
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSE------TTTASTAGSET--TTASTA----G 1210
Query: 1033 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1092
+ + A S S+ ++ + G + P++ S+ N A + ++ + A A
Sbjct: 1211 SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTG 1270
Query: 1093 RTQPSSGVDSAVGTLPATSPQSTS-VQAKGTNKLRKP--------------KLPEVQQAT 1137
+ + ++ T +T+ ST+ V K T+ +P +L T
Sbjct: 1271 SETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVT 1330
Query: 1138 KAPESSDDSEDSSD-------SSSGSEEDGEGPQGAKSAH----TLGPTPSRTETLVEET 1186
AP + +S ++SG G SAH T G T T + +ET
Sbjct: 1331 MAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQET 1390
Query: 1187 AAESSEDDVVAPSQSLL-----SGYMTP 1209
S + V+ S + SGY+ P
Sbjct: 1391 GPVSMGTNTVSMSHTPTNVIKPSGYLQP 1418
Score = 61.6 bits (148), Expect = 5e-09
Identities = 151/801 (18%), Positives = 263/801 (32%), Gaps = 72/801 (8%)
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 698
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 819 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATA--AQAQTGPEEDSGS---- 870
A + + P + +TV G +V + G TA A ++T GS
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236
Query: 871 --------------SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
SE + S E++ET KT + G+ PT
Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
G A + + S+ A S + + S G T A
Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
+ T + T +S+ SE T T G V+ + +
Sbjct: 357 SIMGSETSTDSTTGSETTTASTEGSE------TTTASTEGSEATTVS------TTGSETT 404
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP 1096
+ S+ ++ ++G + +T V + AS T+ + ++ S+++ A T+
Sbjct: 405 TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS---TEGS-EITIASTSDSETTTASTEG 460
Query: 1097 SSGVD-SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1155
S + G+ T+ + S +N + + S++ SE ++ S++G
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 1156 SEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1215
SE +G+++ T+ T S T T V T E++ + +S T T +
Sbjct: 521 SEMTTVSTEGSENT-TVSTTGSET-TTVSTTGLETTTTSTEGSEMTTVS--TTGAETTTD 576
Query: 1216 SQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSR 1275
S T ++ S ++T++ D + + S T G E + +T
Sbjct: 577 STEGSGTTAASTAGSETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTSSET 633
Query: 1276 KPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTK 1335
G+ + S T + +T E V T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMV------------STTGSERTITSTEGSETTTVSATGS 681
Query: 1336 ES--SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE---ASVSPEKTSTTSKGKA 1390
E+ S +G + ++G + + + + + EG E AS++ +T+T S +
Sbjct: 682 ETTVSTEGSGTTTVSITGSE-TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740
Query: 1391 KRDKASGDVKEKKGKGSLGSQ 1411
+ AS + E + GS+
Sbjct: 741 ETTTASTEGSETTSASTTGSE 761
Score = 45.8 bits (107), Expect = 3e-04
Identities = 57/336 (16%), Positives = 115/336 (34%), Gaps = 11/336 (3%)
Query: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
E + + T S+ + S E A E ++ T +++T S + S
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT-VSTTGSETITVSAEGSETTTVT 967
Query: 127 ---AETEKAGKTGNSMPHPATG--KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPA 181
+ET A G+ +T +T + G + + TT VS T E ++ +
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
+ + +AG ++ T S + T EG + + + + + + +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087
Query: 242 PGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ 299
G T G +K +E SE + S + T S + +
Sbjct: 1088 TSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVF 1147
Query: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
+ T G AT + + A + T+ + S + SE ++ S T ++
Sbjct: 1148 TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS---TAGSETT 1204
Query: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
+ A +T+ + + + G+ + P G
Sbjct: 1205 TASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1240
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 95.1 bits (235), Expect = 4e-19
Identities = 219/1081 (20%), Positives = 343/1081 (31%), Gaps = 166/1081 (15%)
Query: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
P TG ++ SP + E E EEE G + +S A
Sbjct: 250 PFEPTGSNPSSSAGTPSPEEEEEEEEE----EEEEEEDEEEEEGLSQSISRISETLAGIY 305
Query: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA----------------PG 243
+++ S D +P +P Q + + + + +A A G
Sbjct: 306 DDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREG 365
Query: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
KV G ALPP P +SE E EE P S + + + A
Sbjct: 366 KVSVEVVTAGGAALPPPLL---PPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPA 422
Query: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE-ESSDSEEETPAAKALLQA 362
A TP P PP + E D E + + + + PAA +
Sbjct: 423 ---ASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGG 479
Query: 363 KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 422
+ + SP APAP GP K +R+ ++ S S
Sbjct: 480 LDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGT 539
Query: 423 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 482
PA P+ + S K ++ ++ + + + D R
Sbjct: 540 QPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRR 599
Query: 483 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 542
RE + P S G G G K + + G
Sbjct: 600 SRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGS 659
Query: 543 EDSESSSEESSDSSD---------GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG 593
E + + + S S+ G VP ++ + L I + K P+
Sbjct: 660 EKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPS 719
Query: 594 PVAVQVKAEKPMDNSE--SSEE---SSDSADSEEAPAAMTAAQAKPALKIPQTKACP--- 645
P + + +SE S EE S D + AA +++ ++ K + KA
Sbjct: 720 PAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSRE--KGSRRKALDGGD 777
Query: 646 -------KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE 698
+ +S K P P+++ ++ P P +G + SSSS
Sbjct: 778 RDRDRDRDRDRDRSSKKARP-------PKESAPSSGPPPKPPVSSG-----SGSSSSSSS 825
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
S + K V V + V K A+ GS+G VK +
Sbjct: 826 CSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIG-----------------VKFSR 868
Query: 759 QEDSES----SEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
+S S +E + +E A A+P K KKT+ KA A + KG
Sbjct: 869 DRESRSPFLKPDERAPTEMAKAAPGSTKP--KKTKVKAKAGAKKTKGTKG---------- 916
Query: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
+ PSK + VR+ S G S+ K+ A + G + +EE
Sbjct: 917 ------KTKPSKTRKKVRSGGGS----GGSGGQVSLKKSKADSCSQAAGTK----GAEET 962
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QAGKQDDS 932
S S EE P K AL P ++ + TP P A +AG + +
Sbjct: 963 SWSGEERAAKVPSTPPPKAAPPPPALTPDSQTV-DSSCKTPEVSFLPEEATEEAGVRGGA 1021
Query: 933 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 992
EE + + E + PA T A + AA+ P A ++ S
Sbjct: 1022 EEEEEEEEEEEE------------------EEEEEEQQPATTTATSTAAAAPSTAPSAGS 1063
Query: 993 TARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDG 1052
TA S +E G + V +PT P + P AG + S
Sbjct: 1064 TAGDSGAED--------------GPASRVSQLPTLPPPM-PWNLPAGVDCT-----TSGV 1103
Query: 1053 KKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSP 1112
++ + N AS Q ++ Q S +PP S++G PA P
Sbjct: 1104 LALTALLFKMEEANLASRAKAQELIQATNQILSHRKPP-----------SSLGMTPAPVP 1152
Query: 1113 QSTSVQAKGTNKLRKPKLP--EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAH 1170
S + ++ L LP P + D + SS SE G+ + K H
Sbjct: 1153 TSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTGLAATSDKREGSSSSEGRGDTDKYLKKLH 1212
Query: 1171 T 1171
T
Sbjct: 1213 T 1213
Score = 82.4 bits (202), Expect = 3e-15
Identities = 192/957 (20%), Positives = 304/957 (31%), Gaps = 129/957 (13%)
Query: 317 PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA 376
PAPP A + AS + + P S S P A T + +
Sbjct: 184 PAPP-PAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEA-YSPP 241
Query: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436
PA E P + A + + EE+ + EE D EEE S + +
Sbjct: 242 PAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETL 301
Query: 437 R--------AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSR----------SS 478
+ P ESPR A P P QV + + R +
Sbjct: 302 AGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEA 361
Query: 479 SEESDSDREALAAMNAAQVKPL---GKS---------PQVKPASTMGM-GPLGKGAGPVP 525
E E + A AA PL G S P+ +P + + P G+ A P P
Sbjct: 362 CREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTP 421
Query: 526 PGKVGPAT---PSAQVGKWEEDSESSSEESSDSSDGEV------PTAVAPAQEKSLGNI- 575
P P + E + S + +G + P PA + G +
Sbjct: 422 AASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLD 481
Query: 576 -------------LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEE 622
Q P+ +PA P AGP + + + E+ E +S S+ ++
Sbjct: 482 LRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQP 541
Query: 623 APAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
AP A A P + S P + + R+ + S + S+
Sbjct: 542 APPA---------------PASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRR 586
Query: 683 AGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV 742
+ T R S S + + + A+ P S
Sbjct: 587 SRSTDRRRGGSRRSRSREKRRRR-----------------RRSASPPPATSSSSSSRRER 629
Query: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT-SVKKTQAKANPAAARAPS 801
GK K +K+ S + D E A +PA + S + A PS
Sbjct: 630 HRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPS 689
Query: 802 AKG----TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857
+ + A + +T K P +P+ + S G +
Sbjct: 690 IQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQK 749
Query: 858 AQAQTGPEEDSGSSEEESDSEEEAE----TLAQVKPSGKTHQIRAALAPAKESPRKGAAP 913
+ ++G S SS E+ + + + + + + A P + +P G P
Sbjct: 750 DRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPP 809
Query: 914 TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 973
PP +G SGSSS S + V+ + S PA
Sbjct: 810 KPPVSSG-----------SGSSSSSSSCSSRKVKLQSKVAVL------IREGVSSTTPAK 852
Query: 974 TPAQAQAASTPRK-ARASESTAR-SSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI 1031
A A S K +R ES + E ++ A T +T V A
Sbjct: 853 DAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAK--- 909
Query: 1032 APKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPV 1091
K + SK ++ G G QVS K + +QAA A++ S +
Sbjct: 910 KTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEER 969
Query: 1092 ARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK---LPE--VQQATKAPESSDDS 1146
A PS+ A PA +P S +V + + P+ LPE ++A + ++
Sbjct: 970 AAKVPSTPPPKAAPPPPALTPDSQTVD----SSCKTPEVSFLPEEATEEAGVRGGAEEEE 1025
Query: 1147 EDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLL 1203
E+ + EE+ + P + T PS T TA +S +D A S L
Sbjct: 1026 EEEEEEEEEEEEEEQQPATTTATSTAAAAPS-TAPSAGSTAGDSGAEDGPASRVSQL 1081
Score = 76.6 bits (187), Expect = 2e-13
Identities = 196/947 (20%), Positives = 316/947 (33%), Gaps = 195/947 (20%)
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
A P +S SS S + S +P A PA P+ T + P
Sbjct: 185 APPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPP-- 242
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRP----AEDSSSSEESDSEEEKTGLAVTVGQAK 716
AP + P GS+P+ + GT P E+ EE + EEE+ GL+ ++ +
Sbjct: 243 ----APEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRIS 298
Query: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
G+ D S ++ +E+
Sbjct: 299 ETLAGIY-------------------------------------DDNSLSQDFPGDESPR 321
Query: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
AQ + T A P + A G + VV A+A + V+
Sbjct: 322 PDAQ---PTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVE-------- 370
Query: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--SDSEEEAETLAQVKPSGKTH 894
V+ G A++P P DS E E EE L+ +P G+
Sbjct: 371 --VVTAGGAALP-----------PPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRA- 416
Query: 895 QIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG----------E 944
A+ +P A PT P A +A + DD S ESD +G
Sbjct: 417 --------ARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAP 468
Query: 945 APAAVTS-------AQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP--------RKARA 989
AP A S + I RSP+ PA PA A AA P RK
Sbjct: 469 APPAADSRWGGLDLRRKILTQRRERYRQRSPS-PAPAPAPAAAAGPPTRKKSRRERKRSG 527
Query: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
A SSSS ++ PA+ + R+ P +H + + S S+ + R
Sbjct: 528 EAKEAASSSSGTQPAPPAPASPWDSKKHRSR-DRKPGSHASSSARRRSRSRSRSRSTRRR 586
Query: 1050 SDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPA 1109
S + ++ S+ + ++ A PP PA
Sbjct: 587 SRSTDRRRGGSRRSRSR-----------EKRRRRRRSASPP-----------------PA 618
Query: 1110 TSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA 1169
TS S+S + + K R +K + S S GSE+ +
Sbjct: 619 TSSSSSSRRERHRGKHRD------GGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGS 672
Query: 1170 HTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSP 1229
+ G SR V + + ++ D+ A +++ G + S A ++PK +
Sbjct: 673 TSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKRE--V 730
Query: 1230 SVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAAS--------------------GT 1269
S + ++ GK K ++ +G S + +E S
Sbjct: 731 LYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDR 790
Query: 1270 TPQKSRKPKKGA---GNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE 1326
+ +K+R PK+ A G P ++ S + + + + VK+ +++
Sbjct: 791 SSKKARPPKESAPSSGPPPKPPVSSGSGSSS---------SSSSCSSRKVKLQSKVAVLI 841
Query: 1327 RKKVVDTT--KESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGA--GEGGEASVSPEKT 1382
R+ V TT K+++ G S K S D+ +R+P K ++ + S P+KT
Sbjct: 842 REGVSSTTPAKDAASAGLGSIGVKFSRDR-ESRSPFLKPDERAPTEMAKAAPGSTKPKKT 900
Query: 1383 STTSKGKAKRDKAS-GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKE 1441
+K AK+ K + G K K + + S G G G GG S KSK +
Sbjct: 901 KVKAKAGAKKTKGTKGKTKPSKTRKKVRSGG-----------GSGG-SGGQVSLKKSKAD 948
Query: 1442 KKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
K E+ + + A + P QTV
Sbjct: 949 SCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTV 995
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 93.2 bits (230), Expect = 2e-18
Identities = 250/1223 (20%), Positives = 416/1223 (34%), Gaps = 154/1223 (12%)
Query: 83 STSESSEEEEEAEAETAKATPRLA----STNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
ST+ EE A + AT + ST S +LG S + + T G T +
Sbjct: 388 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST--T 445
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198
P + T + S +SP + P++ T+ S EE + + ++PG
Sbjct: 446 TPGLSERSTTFHS-SPRSPATTLSPASTTS--SGVSEESTT----SRSRPGSTHTTAFPD 498
Query: 199 SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALP 258
S+ S T P + +S +T P++++ + G + G+
Sbjct: 499 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS-GPSQESTTSHSSSGSTDTALSPGSTT 557
Query: 259 PAKRAKKPEEESESSEEGSESEEEAPAGTRSQ--VKASEKILQVRAASAPAKGTPGKGAT 316
+ E + S GS P T S V+AS ++ S +P +
Sbjct: 558 ALSFGQ--ESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRV-HSSTGSPRTTLSPASSTS 614
Query: 317 PAPPGKAGAV----ASQTKAGKPEEDSESSSEESSD---SEEETPAAKALLQAKASGKT- 368
P G++ A AS P + + EES+ S TP + SG +
Sbjct: 615 PGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSE 674
Query: 369 -SQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQA 427
S + +S A + A G+ ++ G E + S + EA
Sbjct: 675 KSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 734
Query: 428 KPSGKAPQVRAASAP------AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE 481
S ++P + A +ES + P T A+ G EE + S
Sbjct: 735 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 794
Query: 482 SDSDREALAAMNAAQVKPLGKSPQV---KPASTMG--MGPLGKGAGPVPPGKVGPATP-S 535
S E ++ G+ P +PAST +G P +P S
Sbjct: 795 RGST-ETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS 853
Query: 536 AQVGKWEEDSESSSEESSD---SSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA 592
Q G + + E S SS G T ++PA+ + G + + S+P++ P
Sbjct: 854 TQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGE----STPSRLSPSST 909
Query: 593 GPVAVQVKAEKPMDNSESSE--ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT 650
+ P + +S+ S S D+ +PA T++ ++ P T+T
Sbjct: 910 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ--PGSTHT 967
Query: 651 TASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG-LA 709
TA +Q P T+ S GS+ A A SS ++S + G
Sbjct: 968 TAFPDSTTTSDLSQEPT---TSHSSQGSTEATLSPGSTTA--SSLGQQSTTFHSSPGDTE 1022
Query: 710 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
T+ ++ GL AS P S G + P + Q ++ + SS + +
Sbjct: 1023 TTLLPDDTITSGLV--EASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT 1080
Query: 770 DSEEAA-ASPAQVKTSVKKTQAK--------ANPAAARAPSAKGTISAPGKVVTAAAQAK 820
S A+P +V T+ + ++ R+ + S+PG TA +
Sbjct: 1081 PSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTR 1140
Query: 821 QRSPSKVKPPVRNPQNS----TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD 876
+ V P +P +S T G + + + T + P+ + S
Sbjct: 1141 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS 1200
Query: 877 SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSS 936
E T + +P G TH P T P +Q + + S S
Sbjct: 1201 GVSEESTTSHSRP-GSTH----------------TTAFPGSTTMPGVSQ----ESTASHS 1239
Query: 937 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 996
+D T+A + P + + P +T +T ST
Sbjct: 1240 SPGSTDTTLSPGSTTASSLGP-----ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVH 1294
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
SS+ S + PA G T + P++ + A S+ E S S G
Sbjct: 1295 SSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP--APPTTTSAFVELSTTSHG---- 1348
Query: 1057 GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSA-VGTLPATSPQST 1115
+P+S P T S + + R++ S+ V S+ V T SP +
Sbjct: 1349 ---------SPSSTPTTHF---------SASSTTLGRSEESTTVHSSPVATATTPSPARS 1390
Query: 1116 SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPT 1175
+ P Q PESS S S +S + + + HT+
Sbjct: 1391 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSH---------SSTTHTISSP 1441
Query: 1176 PSRTETLVEETAAESSEDDVVA----PSQSLLSGYM-----------TPGLTP------A 1214
PS T LVEE + S +A P S SG T G+TP
Sbjct: 1442 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 1501
Query: 1215 NSQASKATPKLDSSPSVSSTLAA 1237
+ + +++T S S+ +TLA+
Sbjct: 1502 SGRIAESTTFYISPGSMETTLAS 1524
Score = 87.8 bits (216), Expect = 7e-17
Identities = 237/1097 (21%), Positives = 374/1097 (34%), Gaps = 199/1097 (18%)
Query: 271 ESSEEGSESEEEAPA-GTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 329
ESS SEE A G+ + K+S TP A A ++ S
Sbjct: 5 ESSTTSGHSEESATFHGSTTHTKSS---------------TPSTTAALAHTSYHSSLGST 49
Query: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 389
+ + S E S + +P A A A S + S P+ S A
Sbjct: 50 ETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTA 109
Query: 390 PPGK-TGPAVAKAQ----AGKREEDS----QSSSEESDSEEEAPAQAKPSG----KAPQV 436
PG T P +++ + R D+ S + SEE + ++P P
Sbjct: 110 LPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGS 169
Query: 437 RAASAPAKESPRKGAAPAPPRKT----GPAAAQVQVGKQEEDSRSSSEES---DSDREAL 489
++ES ++P P T A+ + SR S E+ + A
Sbjct: 170 TTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS 229
Query: 490 AAMNAAQ------------VKPLGKSPQVKPASTMGMGPLGKGAGPVPP----GKVGPAT 533
+ A+ + P G + + ++T P K P PP V P+T
Sbjct: 230 GLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST 289
Query: 534 PS----AQVGKWEEDSESSS----EESS--DSSDGEVPTAVAPAQEKSLGNILQAKPTSS 583
S + + + S++ EES+ SS G T P + + G + TS
Sbjct: 290 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGR-GEESTTSH 348
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSES---------SEESSDSADSEEAPAAMTAAQAKP 634
+ + P E+P S + S+ S SEE+ A+ ++ A
Sbjct: 349 SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG 408
Query: 635 ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA--------GSSPAVAGGT 686
+ +P + ++ ++ + T A G+ T+P SSP T
Sbjct: 409 TIVLPARSTTSVLLGESTTSPISSGSMETTA--LPGSTTTPGLSERSTTFHSSPRSPATT 466
Query: 687 QRPAEDSSS--SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLP 744
PA +SS SEES + + G T S + S S G +LP
Sbjct: 467 LSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTP-GLSRHSTTSHSSPGSTDTTLLP 525
Query: 745 GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP-------------------------- 778
T + ++S +S S S + A SP
Sbjct: 526 AST------TTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 579
Query: 779 --------------AQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSP 824
+V +S + +PA++ +P +G S + A+ P
Sbjct: 580 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE-STAFQTHPASTHTTPSPP 638
Query: 825 SKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETL 884
S PV + ST R P S P+ A+ +G E S D+ +
Sbjct: 639 STATAPV---EESTTYHRSPGSTPTTH---FPASSTTSGHSEKSTIFHSSPDASGTTPSS 692
Query: 885 AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE 944
A SG+ + ++P P T P ++A + SS S +
Sbjct: 693 AHSTTSGRGESTTSRISPGSTE----ITTLPGSTTTPGLSEA---STTFYSSPRSPTTTL 745
Query: 945 APAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDE 1004
+PA++TS V + + S + P +T + AST + EST SSS E
Sbjct: 746 SPASMTSLGVGE------ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTE 799
Query: 1005 DVIPATQCLTPGIRTNVVTMPTAHPRIA--------PKASMAGASSSKESSRISDGKKQE 1056
+ T + T T H R A ++ +G + + S Q
Sbjct: 800 TTV-FPHSTTTSVHGEEPT--TFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT 856
Query: 1057 G-PAT-------QVSKKNPASLPLTQAALKVLAQKAS----EAQPPVARTQPSSGVDSAV 1104
G PAT + S P+S T L S E+ P +R PSS +
Sbjct: 857 GLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP--SRLSPSS---TET 911
Query: 1105 GTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQ 1164
TLP SP + S+ K T P+ P+ AT +P ++ S S +SS+ + G
Sbjct: 912 TTLPG-SPTTPSLSEKSTTFYTSPRSPD---ATLSPATTTSSGVSEESSTSHSQPG---- 963
Query: 1165 GAKSAHTLG-PTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATP 1223
S HT P + T L +E S SQ ++PG T A+S ++T
Sbjct: 964 ---STHTTAFPDSTTTSDLSQEPTTSHS-------SQGSTEATLSPGSTTASSLGQQST- 1012
Query: 1224 KLDSSPSVSSTLAAKDD 1240
SSP + T DD
Sbjct: 1013 TFHSSPGDTETTLLPDD 1029
Score = 71.6 bits (174), Expect = 5e-12
Identities = 147/741 (19%), Positives = 267/741 (36%), Gaps = 101/741 (13%)
Query: 607 NSESSEESSDSADSEEAPAAMTAAQAKPAL--KIPQTKACPKKTNTTASAKVAPVRVGTQ 664
+ ES+ + ++ + + TAA A + + T+ + ++T S + +
Sbjct: 13 SEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHS 72
Query: 665 APRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724
+P T PAGS+P+V G P+ SS S E+ T + GL
Sbjct: 73 SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMET-----------TALPGSTTKPGLSE 121
Query: 725 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
K+ + ++P P T + + E+S +S S A P ++
Sbjct: 122 KSTTF--------YSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG---ST 170
Query: 785 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN----PQNSTVL 840
++ + A+ +P T +PG TA++ + + +P P N+T
Sbjct: 171 TMPGLSQESTASHSSPGPTDTTLSPGS-TTASSLGPEYTTFHSRPGSTETTLLPDNTTAS 229
Query: 841 ARGPASVP----------SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPS 890
AS+P ++ A +T Q ++ S S +++ T A V+PS
Sbjct: 230 GLLEASMPVHSSTRSPHTTLSPAGSTTRQGES-TTFHSWPSSKDTRPAPPTTTSAFVEPS 288
Query: 891 GKTHQIRAALAPAKESPRKGAAPTPPGKT----GPSAAQA---GKQDDSGSSSEESDSDG 943
+H +++ S R + T P + Q + D + EES +
Sbjct: 289 TTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSH 348
Query: 944 EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESED 1003
+ S+ + +P + P +T S+ R+ ESTA SS ++
Sbjct: 349 SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG 408
Query: 1004 EDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVS 1063
V+PA + ++ +P +S + +++ S + G + S
Sbjct: 409 TIVLPA---------RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSS 459
Query: 1064 KKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTN 1123
++PA+ T + + SE + +R++P S T P ST+ +
Sbjct: 460 PRSPAT---TLSPASTTSSGVSE-ESTTSRSRPGS-------THTTAFPDSTTTPGLSRH 508
Query: 1124 KLRKPKLPEVQQATKAPESSDDSEDS-----SDSSSGSEEDGEGP---------QGAKSA 1169
P T P S+ S S S SSSGS + P Q + +
Sbjct: 509 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 568
Query: 1170 H--------TLGPTPSRTETLVEET----AAESSEDDVVAPSQSL---LSGYMTPGLT-P 1213
H TL P + + +VE + ++ S ++P+ S L G T T P
Sbjct: 569 HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 628
Query: 1214 ANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA--AGMLSPKT--GGKEAASGT 1269
A++ + + P ++P ST + P + +G T ASGT
Sbjct: 629 ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT 688
Query: 1270 TPQKSRKPKKGAGNPQASTLA 1290
TP + G G S ++
Sbjct: 689 TPSSAHSTTSGRGESTTSRIS 709
Score = 67.0 bits (162), Expect = 1e-10
Identities = 158/770 (20%), Positives = 266/770 (34%), Gaps = 84/770 (10%)
Query: 645 PKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG----SSPAVAGGTQRPAEDSSSSEESD 700
P+ + T+ ++ + G+ K+ T ++ A S + G T+ SS+
Sbjct: 4 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63
Query: 701 SEEEKTG------LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
SEE K +A TV A S L + P+ + TA LPG T
Sbjct: 64 SEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTA--LPGST---TKPG 118
Query: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
+EK SS D+ AS S + T + + P + + G+ + PG ++
Sbjct: 119 LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG--LS 176
Query: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
+ A SP + +P ++T + GP + +T SG E
Sbjct: 177 QESTASHSSPGPTDTTL-SPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE-- 233
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT----PPGKTGPSAAQAGKQD 930
A + T L+PA + R+G + T P K A
Sbjct: 234 ----------ASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA 283
Query: 931 DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
S+ S P SA+ L+ + + P +T S R
Sbjct: 284 FVEPSTTSHGSPSSIPTTHISARSTTSGLV-EESTTYHSSPGSTQTMHFPESDTTSGRGE 342
Query: 991 ESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050
EST SS+ T P + +V PT++ +P ++ A++ S +
Sbjct: 343 ESTTSHSSTTH--------TISSAPSTTSALVEEPTSY-HSSPGST---ATTHFPDSSTT 390
Query: 1051 DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPAT 1110
G+ +E A+ S+ ++ L + + S P + + ++ + + T P
Sbjct: 391 SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGL 449
Query: 1111 SPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS--GSEEDGEGPQG--- 1165
S +ST+ + P+ P + + SS SE+S+ S S GS P
Sbjct: 450 SERSTTFHSS-------PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT 502
Query: 1166 ---AKSAHTLGPTPSRTETLV----EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQA 1218
++ + T +P T+T + T+ S E S ++PG T A S
Sbjct: 503 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFG 562
Query: 1219 SKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1278
++T + S +TL PD + +A+ + TG +P S P
Sbjct: 563 QESTTFHSNPGSTHTTLF----PDSTTSSGIVEASTRVHSSTGSPRTT--LSPASSTSPG 616
Query: 1279 KGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESS 1338
+ T ++ T P P + A + V+ T SS
Sbjct: 617 LQGESTAFQTHPASTHTT------PSPPSTA---TAPVEESTTYHRSPGSTPTTHFPASS 667
Query: 1339 RKGWESRKRKLSGDQPAAR--TPRSKKKKKLGAGEGGEASVSPEKTSTTS 1386
S K + P A TP S G GE + +SP T T+
Sbjct: 668 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 717
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.296 0.114 0.298
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,920,857
Number of Sequences: 37866
Number of extensions: 3704214
Number of successful extensions: 67165
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 686
Number of HSP's successfully gapped in prelim test: 2613
Number of HSP's that attempted gapping in prelim test: 22915
Number of HSP's gapped (non-prelim): 25494
length of query: 1488
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1373
effective length of database: 13,892,928
effective search space: 19074990144
effective search space used: 19074990144
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.