Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 205360905
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205360905 testis-specific serine protease 1 [Homo sapiens]
(318 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 673 0.0
gi|21614531 testisin isoform 2 [Homo sapiens] 336 1e-92
gi|5803197 testisin isoform 1 [Homo sapiens] 336 2e-92
gi|21614533 testisin isoform 3 [Homo sapiens] 314 6e-86
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 221 5e-58
gi|4506153 prostasin preproprotein [Homo sapiens] 213 2e-55
gi|58218970 protease, serine, 36 [Homo sapiens] 202 4e-52
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 197 8e-51
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 197 1e-50
gi|117956391 protease, serine, 33 [Homo sapiens] 193 1e-49
gi|148806900 epidermis-specific serine protease-like protein [Ho... 193 2e-49
gi|13994276 marapsin [Homo sapiens] 188 5e-48
gi|11545839 protease, serine, 22 [Homo sapiens] 186 3e-47
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 185 5e-47
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 183 2e-46
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 183 2e-46
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 183 2e-46
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 182 3e-46
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 182 3e-46
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 179 2e-45
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 175 4e-44
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 175 4e-44
gi|223942069 enterokinase precursor [Homo sapiens] 174 1e-43
gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 172 5e-43
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 172 5e-43
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 171 6e-43
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 171 6e-43
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 171 8e-43
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 171 1e-42
gi|4503627 coagulation factor XI precursor [Homo sapiens] 169 3e-42
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 673 bits (1736), Expect = 0.0
Identities = 318/318 (100%), Positives = 318/318 (100%)
Query: 1 MGARGALLLALLLARAGLGKPGELGALQAGPGAARRPGGGGREEACGHREIHALVAGGVE 60
MGARGALLLALLLARAGLGKPGELGALQAGPGAARRPGGGGREEACGHREIHALVAGGVE
Sbjct: 1 MGARGALLLALLLARAGLGKPGELGALQAGPGAARRPGGGGREEACGHREIHALVAGGVE 60
Query: 61 SARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPW 120
SARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPW
Sbjct: 61 SARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPW 120
Query: 121 NLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPD 180
NLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPD
Sbjct: 121 NLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPD 180
Query: 181 CWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDG 240
CWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDG
Sbjct: 181 CWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDG 240
Query: 241 SVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSHST 300
SVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSHST
Sbjct: 241 SVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSHST 300
Query: 301 PRPNPSQLLLLLALLWAP 318
PRPNPSQLLLLLALLWAP
Sbjct: 301 PRPNPSQLLLLLALLWAP 318
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 336 bits (862), Expect = 1e-92
Identities = 172/320 (53%), Positives = 217/320 (67%), Gaps = 18/320 (5%)
Query: 1 MGARGALLLALLLARAGLGKP-GELGALQAGPGAARRPGGGGREEACGHREIHALVAGGV 59
MGARGALLLALLLARAGL KP + A +GP CG R I + + GG
Sbjct: 1 MGARGALLLALLLARAGLRKPESQEAAPLSGP--------------CGRRVITSRIVGGE 46
Query: 60 ESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYY-PSEWTVQLGELTSRPT 118
++ GRWPWQ SLRL H CG SLLS RW L+AAHCF+ PS W VQ G+LTS P+
Sbjct: 47 DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFGQLTSMPS 106
Query: 119 PWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHR 178
W+L+AY +RY V +I ++P LG DIAL++L++ VTY +IQPIC+++STF F +R
Sbjct: 107 FWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENR 166
Query: 179 PDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAE 238
DCWVTGWG I LP P+ L+E QV I+NN+ CN+LF + S R I+ M CAG
Sbjct: 167 TDCWVTGWGYIKEDEA-LPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNA 225
Query: 239 DGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSH 298
G D C GDSGGPL C+K+GLWYQ+G+VSWG+ CG+PNRPGVYTNIS +F WI+++M+
Sbjct: 226 QGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQ 285
Query: 299 S-TPRPNPSQLLLLLALLWA 317
S +P+PS LL LLWA
Sbjct: 286 SGMSQPDPSWPLLFFPLLWA 305
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 336 bits (861), Expect = 2e-92
Identities = 172/322 (53%), Positives = 218/322 (67%), Gaps = 20/322 (6%)
Query: 1 MGARGALLLALLLARAGLGKP-GELGALQAGPGAARRPGGGGREEACGHREIHALVAGGV 59
MGARGALLLALLLARAGL KP + A +GP CG R I + + GG
Sbjct: 1 MGARGALLLALLLARAGLRKPESQEAAPLSGP--------------CGRRVITSRIVGGE 46
Query: 60 ESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYY---PSEWTVQLGELTSR 116
++ GRWPWQ SLRL H CG SLLS RW L+AAHCF+ + PS W VQ G+LTS
Sbjct: 47 DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSM 106
Query: 117 PTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFV 176
P+ W+L+AY +RY V +I ++P LG DIAL++L++ VTY +IQPIC+++STF F
Sbjct: 107 PSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFE 166
Query: 177 HRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAG 236
+R DCWVTGWG I LP P+ L+E QV I+NN+ CN+LF + S R I+ M CAG
Sbjct: 167 NRTDCWVTGWGYIKEDEA-LPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAG 225
Query: 237 AEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVM 296
G D C GDSGGPL C+K+GLWYQ+G+VSWG+ CG+PNRPGVYTNIS +F WI+++M
Sbjct: 226 NAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 285
Query: 297 SHS-TPRPNPSQLLLLLALLWA 317
+ S +P+PS LL LLWA
Sbjct: 286 AQSGMSQPDPSWPLLFFPLLWA 307
>gi|21614533 testisin isoform 3 [Homo sapiens]
Length = 300
Score = 314 bits (805), Expect = 6e-86
Identities = 166/322 (51%), Positives = 212/322 (65%), Gaps = 34/322 (10%)
Query: 1 MGARGALLLALLLARAGLGKP-GELGALQAGPGAARRPGGGGREEACGHREIHALVAGGV 59
MGARGALLLALLLARAGL KP + A +GP CG R I + + GG
Sbjct: 1 MGARGALLLALLLARAGLRKPESQEAAPLSGP--------------CGRRVITSRIVGGE 46
Query: 60 ESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYY---PSEWTVQLGELTSR 116
++ GRWPWQ SLRL H CG SLLS RW L+AAHCF+ + PS W VQ G+LTS
Sbjct: 47 DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSM 106
Query: 117 PTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFV 176
P+ W+L+AY +RY V +I ++P LG DIAL++L++ VTY +IQPIC+++STF F
Sbjct: 107 PSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFE 166
Query: 177 HRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAG 236
+R DCWVTGWG I LP P+ L+E QV I+NN+ CN+LF + S R I+ M
Sbjct: 167 NRTDCWVTGWGYIK-EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDM---- 221
Query: 237 AEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVM 296
GDSGGPL C+K+GLWYQ+G+VSWG+ CG+PNRPGVYTNIS +F WI+++M
Sbjct: 222 ----------GDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 271
Query: 297 SHS-TPRPNPSQLLLLLALLWA 317
+ S +P+PS LL LLWA
Sbjct: 272 AQSGMSQPDPSWPLLFFPLLWA 293
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 221 bits (564), Expect = 5e-58
Identities = 135/318 (42%), Positives = 177/318 (55%), Gaps = 30/318 (9%)
Query: 3 ARGALLLALLLARAGLGKPGELGALQAGPGAARRPGGGGREEACGHREIHALVAGGVESA 62
A GA L LLLA G+ L LQ G G + GGR + GG +
Sbjct: 2 ALGACGLLLLLAVPGVS----LRTLQPGCGRPQVSDAGGR------------IVGGHAAP 45
Query: 63 RGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNL 122
G WPWQASLRLRR H CGGSLLS +WVL+AAHCF S++ V LGEL +P
Sbjct: 46 AGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPH-- 103
Query: 123 RAYSSRYKVQDIIVNPDALGV--LRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPD 180
+S+ V+ II++ G DIAL+ L+ VT ++ I P+C+ ++ +F
Sbjct: 104 --FST---VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIR 158
Query: 181 CWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDG 240
CWVTGWG + G PLPPPY+LRE +V++++ C + P S++ M CA G
Sbjct: 159 CWVTGWGY-TREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGG-SILQPDMLCAR---G 213
Query: 241 SVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSHST 300
D C+ DSGGPLVC +G W Q GIVSWG CG+PNRPGVYT + Y +WIRR ++ S
Sbjct: 214 PGDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASG 273
Query: 301 PRPNPSQLLLLLALLWAP 318
+ L LLA + P
Sbjct: 274 GSESGYPRLPLLAGFFLP 291
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 213 bits (542), Expect = 2e-55
Identities = 123/309 (39%), Positives = 173/309 (55%), Gaps = 31/309 (10%)
Query: 13 LARAGLGKPGELGA---------LQAGPGAARRPGGGGREEACGHREIHALVAGGVESAR 63
+A+ G+ PG+LGA L++G GA G E CG A + GG +
Sbjct: 1 MAQKGVLGPGQLGAVAILLYLGLLRSGTGAE------GAEAPCGVAP-QARITGGSSAVA 53
Query: 64 GRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLR 123
G+WPWQ S+ H CGGSL+S +WVLSAAHCF ++ + V+LG L
Sbjct: 54 GQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA-------HQLD 106
Query: 124 AYSSRYKV---QDIIVNPDALGV-LRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRP 179
+YS KV +DII +P L + DIALL+L+ +T++ YI+PIC+ ++ +F +
Sbjct: 107 SYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGL 166
Query: 180 DCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFE---QPSSRSMIWDSMFCAG 236
C VTGWG ++PS + L P L++ +V +++ CN L+ +P + + M CAG
Sbjct: 167 HCTVTGWGHVAPSVSLLTPK-PLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAG 225
Query: 237 AEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVM 296
+G D C+GDSGGPL C +GLWY GIVSWG CG NRPGVYT S Y WI+ +
Sbjct: 226 YVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
Query: 297 SHSTPRPNP 305
+ PR P
Sbjct: 286 TELQPRVVP 294
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 202 bits (513), Expect = 4e-52
Identities = 108/264 (40%), Positives = 149/264 (56%), Gaps = 10/264 (3%)
Query: 46 CGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYY--- 102
CG E A + GG + G WPWQ SL H CGGSL++ WVLSAAHCF +
Sbjct: 38 CGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEP 97
Query: 103 PSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAY 162
+EW+V LG + S+ P L +R ++ + L D+ALLRLAS +
Sbjct: 98 AAEWSVLLG-VHSQDGP--LDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPA 154
Query: 163 IQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQP 222
+ P+C+ ++ FVH CW TGWG + + PLP P+ L+E ++ +L C L+ QP
Sbjct: 155 VWPVCLPRASHRFVHGTACWATGWGDVQEAD-PLPLPWVLQEVELRLLGEATCQCLYSQP 213
Query: 223 SSRSM---IWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRP 279
++ I M CAG +G DTC+GDSGGPLVC++ G W+Q GI S+G CG+ NRP
Sbjct: 214 GPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRP 273
Query: 280 GVYTNISVYFHWIRRVMSHSTPRP 303
GV+T ++ Y WIR + S P P
Sbjct: 274 GVFTAVATYEAWIREQVMGSEPGP 297
Score = 77.4 bits (189), Expect = 2e-14
Identities = 71/262 (27%), Positives = 111/262 (42%), Gaps = 30/262 (11%)
Query: 42 REEACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCF---- 97
REE C AL G G WPW+A + + C G+L+S WVL+ A CF
Sbjct: 314 REENC----TIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPN 369
Query: 98 QKHYYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSV 157
P + L SRP +V ++ + +A +D+ALL+L + V
Sbjct: 370 SSDSPPRDLDAWRVLLPSRP---------RAERVARLVQHENASWDNASDLALLQLRTPV 420
Query: 158 TYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNY 217
+A +P+C+ F+ C + WG G P P L EA+ +L C+
Sbjct: 421 NLSAASRPVCLPHPEHYFLPGSRCRLARWG----RGEPALGPGALLEAE--LLGGWWCHC 474
Query: 218 LF-EQPSSRSMIWD---SMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDC 273
L+ Q ++ + D ++ A E V +C DS L+C ++G W+ GI + C
Sbjct: 475 LYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGC 534
Query: 274 GQPNRPGVYTNISVYFHWIRRV 295
RP + + + WI V
Sbjct: 535 ---LRPRAFFPLQTHGPWISHV 553
Score = 64.3 bits (155), Expect = 1e-10
Identities = 59/214 (27%), Positives = 88/214 (41%), Gaps = 35/214 (16%)
Query: 66 WPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWT-----VQLGELTSRPTPW 120
WPW A + + C G LL+ WVL+A HC + P T V LG + P
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLR---PGSTTVPYIEVYLGRAGASSLP- 656
Query: 121 NLRAYSSRYKVQDIIVN---PDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVH 177
++V ++++ P LG LR +ALL L+S V + PIC+ +
Sbjct: 657 ------QGHQVSRLVISIRLPQHLG-LRPPLALLELSSRVEPSPSALPICLHPA--GIPP 707
Query: 178 RPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGA 237
CWV GW P A V+IL C+ L++ ++ C
Sbjct: 708 GASCWVLGW--------KEPQDRVPVAAAVSILTQRICDCLYQ-----GILPPGTLCVLY 754
Query: 238 EDGSVDTCKGDSGGPLVCD-KDGLWYQVGIVSWG 270
+G + C+ S PL+C +G W VG+ G
Sbjct: 755 AEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQG 788
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 197 bits (502), Expect = 8e-51
Identities = 105/258 (40%), Positives = 145/258 (56%), Gaps = 21/258 (8%)
Query: 45 ACGHREIHAL-VAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYP 103
ACGHR ++ + GG S +WPWQASL+ + H CGGS+++ W+++AAHC Y P
Sbjct: 206 ACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLP 265
Query: 104 SEWTVQLG--ELTSRPTPWNLR---AYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVT 158
WT+Q+G L P P +L Y S+YK P LG NDIAL++LA +T
Sbjct: 266 KSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYK-------PKRLG---NDIALMKLAGPLT 315
Query: 159 YNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYL 218
+N IQP+C+ +S NF CW +GWG P N A V +++N CN+
Sbjct: 316 FNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLN--HAAVPLISNKICNH- 372
Query: 219 FEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNR 278
+ +I SM CAG G VD+C+GDSGGPLVC + LW VG S+G+ C + N+
Sbjct: 373 --RDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNK 430
Query: 279 PGVYTNISVYFHWIRRVM 296
PGVYT ++ + WI M
Sbjct: 431 PGVYTRVTSFLDWIHEQM 448
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 197 bits (500), Expect = 1e-50
Identities = 103/242 (42%), Positives = 138/242 (57%), Gaps = 16/242 (6%)
Query: 55 VAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELT 114
+ GG E+ G WPWQ SLRL H CGGSL++ W+L+AAHCF+ + P +W G T
Sbjct: 187 ILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGIST 246
Query: 115 SRPTPWNLRAYSSRYKVQDIIV-NPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTF 173
+ P R +V++I++ N NDIAL+RL +SVT+ I +C+ ++T
Sbjct: 247 TFP--------KLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQ 298
Query: 174 NFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMF 233
N +VTGWG +G +P LR+ QV I++N CN S I M
Sbjct: 299 NIPPGSTAYVTGWGAQEYAGHTVP---ELRQGQVRIISNDVCN---APHSYNGAILSGML 352
Query: 234 CAGAEDGSVDTCKGDSGGPLVC-DKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWI 292
CAG G VD C+GDSGGPLV D LW+ VGIVSWG CG P++PGVYT ++ Y WI
Sbjct: 353 CAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412
Query: 293 RR 294
R+
Sbjct: 413 RQ 414
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 193 bits (491), Expect = 1e-49
Identities = 103/263 (39%), Positives = 150/263 (57%), Gaps = 10/263 (3%)
Query: 40 GGREEACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQK 99
G + ACG + + + GG + G WPWQAS++ R H CGGSL++ +WVL+AAHCF +
Sbjct: 22 GRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPR 81
Query: 100 HYYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPD-ALGVLRNDIALLRLASSVT 158
P+E+ V+LG L T + R S V+ +++ PD + R D+ALL+L V
Sbjct: 82 RALPAEYRVRLGALRLGST--SPRTLS--VPVRRVLLPPDYSEDGARGDLALLQLRRPVP 137
Query: 159 YNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYL 218
+A +QP+C+ C VTGWG + P G PLP L+ +V +L++ C+ L
Sbjct: 138 LSARVQPVCLPVPGARPPPGTPCRVTGWGSLRP-GVPLPEWRPLQGVRVPLLDSRTCDGL 196
Query: 219 F----EQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCG 274
+ + P + ++ CAG G D C+GDSGGPL C + G W VG+VSWG C
Sbjct: 197 YHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCA 256
Query: 275 QPNRPGVYTNISVYFHWIRRVMS 297
PNRPGVYT+++ Y WI+ +S
Sbjct: 257 LPNRPGVYTSVATYSPWIQARVS 279
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 193 bits (490), Expect = 2e-49
Identities = 104/261 (39%), Positives = 146/261 (55%), Gaps = 17/261 (6%)
Query: 46 CGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSE 105
CG + V GG ++A GRWPWQ SL CGGSL+S R +L+AAHC Q +
Sbjct: 19 CGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFS 78
Query: 106 WTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQP 165
+TV LG +T + ++ Y S+ I+++P D+ALL+L+S VT+ + I P
Sbjct: 79 YTVWLGSITVGDSRKRVKYYVSK-----IVIHPKYQDTTA-DVALLKLSSQVTFTSAILP 132
Query: 166 ICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYN--LREAQVTILNNTRCNYLFEQ-- 221
IC+ S T P CWVTGWG + S Y+ L+EA+V I++ C L+
Sbjct: 133 ICLPSVTKQLAIPPFCWVTGWGKVKESS---DRDYHSALQEAEVPIIDRQACEQLYNPIG 189
Query: 222 ---PSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNR 278
P+ +I + CAG D+CKGDSGGPL C DG+W Q G+VSWG++CG+ +
Sbjct: 190 IFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGK-SL 248
Query: 279 PGVYTNISVYFHWIRRVMSHS 299
PGVYTN+ Y WI +S +
Sbjct: 249 PGVYTNVIYYQKWINATISRA 269
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 188 bits (478), Expect = 5e-48
Identities = 100/259 (38%), Positives = 145/259 (55%), Gaps = 14/259 (5%)
Query: 45 ACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPS 104
ACG + + GG ++ G WPWQ S++ H CGGSL++ +WVL+AAHCF+ S
Sbjct: 25 ACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETS 84
Query: 105 EWTVQLG-ELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRN-DIALLRLASSVTYNAY 162
+ V LG +P P + A +V+ + NP G + D+AL+ L + V + Y
Sbjct: 85 LYQVLLGARQLVQPGPHAMYA-----RVRQVESNPLYQGTASSADVALVELEAPVPFTNY 139
Query: 163 IQPICIESSTFNFVHRPDCWVTGWGLISPSGTPL-PPPYNLREAQVTILNNTRCNYLFEQ 221
I P+C+ + F +CWVTGWG SPS L P P L++ V I++ +CN L+ +
Sbjct: 140 ILPVCLPDPSVIFETGMNCWVTGWG--SPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSK 197
Query: 222 PSS----RSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPN 277
+ I + M CAG E+G D CKGDSGGPLVC W Q G++SWG C + N
Sbjct: 198 DTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQN 257
Query: 278 RPGVYTNISVYFHWIRRVM 296
RPGVY ++ + +WI R++
Sbjct: 258 RPGVYIRVTAHHNWIHRII 276
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 186 bits (471), Expect = 3e-47
Identities = 96/258 (37%), Positives = 144/258 (55%), Gaps = 14/258 (5%)
Query: 45 ACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYY-P 103
ACG + V GG +S WPW S++ H C GSLL+ RWV++AAHCF+ + P
Sbjct: 40 ACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKP 99
Query: 104 SEWTVQLGELTSRPTPWNLRAYSSR-YKVQDIIVNPDALGVLRN----DIALLRLASSVT 158
++V LG W L SR KV V P + + DIAL+RL S+
Sbjct: 100 YLFSVLLGA-------WQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQ 152
Query: 159 YNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYL 218
++ + PIC+ ++ + CW++GWG I G PLP P L++ +V I+++ C++L
Sbjct: 153 FSERVLPICLPDASIHLPPNTHCWISGWGSIQ-DGVPLPHPQTLQKLKVPIIDSEVCSHL 211
Query: 219 FEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNR 278
+ + + + I + M CAG +G D C GDSGGPL+C DG W GI+SWG C + NR
Sbjct: 212 YWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNR 271
Query: 279 PGVYTNISVYFHWIRRVM 296
PGVY ++S + W+ +++
Sbjct: 272 PGVYISLSAHRSWVEKIV 289
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 185 bits (469), Expect = 5e-47
Identities = 100/254 (39%), Positives = 147/254 (57%), Gaps = 21/254 (8%)
Query: 46 CGHREIHALVAG-----GVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKH 100
CG + ++++ G G S G WPWQAS++ + RH CG SL+S RW+LSAAHCF K
Sbjct: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
Query: 101 YYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPD-ALGVLRNDIALLRLASSVTY 159
+WTV G + ++P Y +R KVQ+II + + + L +DIAL++LA V++
Sbjct: 231 NNSKDWTVNFGIVVNKP-------YMTR-KVQNIIFHENYSSPGLHDDIALVQLAEEVSF 282
Query: 160 NAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLF 219
YI+ IC+ + + VTGWG + +G+ P L+E + I++N CN +
Sbjct: 283 TEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGS---FPVILQEDFLKIIDNKICNASY 339
Query: 220 EQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVC-DKDGLWYQVGIVSWGMDCGQPNR 278
+ + D+M CAG G D C+ DSGGPL D +W+ VGIVSWG CG+ N+
Sbjct: 340 ---AYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNK 396
Query: 279 PGVYTNISVYFHWI 292
PGVYT ++ Y +WI
Sbjct: 397 PGVYTRVTSYRNWI 410
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 183 bits (465), Expect = 2e-46
Identities = 108/288 (37%), Positives = 149/288 (51%), Gaps = 26/288 (9%)
Query: 16 AGLGKPGELGALQAGPGAARRPGGG---GRE--EACGHREIHALVAGGVESARGRWPWQA 70
A G PG + G A G GR+ +ACGHR + GG+ + +WPWQ
Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMI--GGLPAPNKKWPWQV 178
Query: 71 SLRLRRRHRCGGSLLSRRWVLSAAHCFQKH--YYPSEWTVQLGELTSRPTPWNLRAYSSR 128
SL+ H CGGSL+ RRWVL+AAHC + + W + + +
Sbjct: 179 SLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA-----------GIGRWDQA 227
Query: 129 YKVQDIIVNPDAL--GVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGW 186
+K + I+ P L +DIAL LA SV Y+++IQP C+ F +CWVTGW
Sbjct: 228 WKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGW 287
Query: 187 GLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQP--SSRSMIWDSMFCAGAEDGSVDT 244
G +S S + P P L+E ++ I+ + +C + + S M+ C G D D
Sbjct: 288 GQVSESVSG-PMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVC-GYNDQGKDA 345
Query: 245 CKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWI 292
C+GDSGGPLVC+ +G W QVGIVSWG+ CG+ PGVYT +S Y WI
Sbjct: 346 CQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWI 393
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 183 bits (465), Expect = 2e-46
Identities = 108/288 (37%), Positives = 149/288 (51%), Gaps = 26/288 (9%)
Query: 16 AGLGKPGELGALQAGPGAARRPGGG---GRE--EACGHREIHALVAGGVESARGRWPWQA 70
A G PG + G A G GR+ +ACGHR + GG+ + +WPWQ
Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMI--GGLPAPNKKWPWQV 178
Query: 71 SLRLRRRHRCGGSLLSRRWVLSAAHCFQKH--YYPSEWTVQLGELTSRPTPWNLRAYSSR 128
SL+ H CGGSL+ RRWVL+AAHC + + W + + +
Sbjct: 179 SLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA-----------GIGRWDQA 227
Query: 129 YKVQDIIVNPDAL--GVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGW 186
+K + I+ P L +DIAL LA SV Y+++IQP C+ F +CWVTGW
Sbjct: 228 WKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGW 287
Query: 187 GLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQP--SSRSMIWDSMFCAGAEDGSVDT 244
G +S S + P P L+E ++ I+ + +C + + S M+ C G D D
Sbjct: 288 GQVSESVSG-PMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVC-GYNDQGKDA 345
Query: 245 CKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWI 292
C+GDSGGPLVC+ +G W QVGIVSWG+ CG+ PGVYT +S Y WI
Sbjct: 346 CQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWI 393
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 183 bits (465), Expect = 2e-46
Identities = 108/288 (37%), Positives = 149/288 (51%), Gaps = 26/288 (9%)
Query: 16 AGLGKPGELGALQAGPGAARRPGGG---GRE--EACGHREIHALVAGGVESARGRWPWQA 70
A G PG + G A G GR+ +ACGHR + GG+ + +WPWQ
Sbjct: 121 ATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMI--GGLPAPNKKWPWQV 178
Query: 71 SLRLRRRHRCGGSLLSRRWVLSAAHCFQKH--YYPSEWTVQLGELTSRPTPWNLRAYSSR 128
SL+ H CGGSL+ RRWVL+AAHC + + W + + +
Sbjct: 179 SLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA-----------GIGRWDQA 227
Query: 129 YKVQDIIVNPDAL--GVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGW 186
+K + I+ P L +DIAL LA SV Y+++IQP C+ F +CWVTGW
Sbjct: 228 WKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECWVTGW 287
Query: 187 GLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQP--SSRSMIWDSMFCAGAEDGSVDT 244
G +S S + P P L+E ++ I+ + +C + + S M+ C G D D
Sbjct: 288 GQVSESVSG-PMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVC-GYNDQGKDA 345
Query: 245 CKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWI 292
C+GDSGGPLVC+ +G W QVGIVSWG+ CG+ PGVYT +S Y WI
Sbjct: 346 CQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWI 393
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 182 bits (463), Expect = 3e-46
Identities = 95/251 (37%), Positives = 138/251 (54%), Gaps = 13/251 (5%)
Query: 45 ACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPS 104
ACG V GG E++ WPWQ S++ ++H CGGS+L WVL+AAHCF+KH
Sbjct: 190 ACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVF 249
Query: 105 EWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQ 164
W V+ G L ++ S + II+ + + NDIAL++L +T++ ++
Sbjct: 250 NWKVRAGS-------DKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVR 302
Query: 165 PICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSS 224
PIC+ W+ GWG +G + L +A V ++++TRCN +
Sbjct: 303 PICLPFFDEELTPATPLWIIGWGFTKQNGGKMSD--ILLQASVQVIDSTRCN---ADDAY 357
Query: 225 RSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTN 284
+ + + M CAG +G VDTC+GDSGGPL+ D W+ VGIVSWG CG P+ PGVYT
Sbjct: 358 QGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD-QWHVVGIVSWGYGCGGPSTPGVYTK 416
Query: 285 ISVYFHWIRRV 295
+S Y +WI V
Sbjct: 417 VSAYLNWIYNV 427
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 182 bits (463), Expect = 3e-46
Identities = 95/251 (37%), Positives = 138/251 (54%), Gaps = 13/251 (5%)
Query: 45 ACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPS 104
ACG V GG E++ WPWQ S++ ++H CGGS+L WVL+AAHCF+KH
Sbjct: 195 ACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVF 254
Query: 105 EWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQ 164
W V+ G L ++ S + II+ + + NDIAL++L +T++ ++
Sbjct: 255 NWKVRAGS-------DKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVR 307
Query: 165 PICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSS 224
PIC+ W+ GWG +G + L +A V ++++TRCN +
Sbjct: 308 PICLPFFDEELTPATPLWIIGWGFTKQNGGKMSD--ILLQASVQVIDSTRCN---ADDAY 362
Query: 225 RSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTN 284
+ + + M CAG +G VDTC+GDSGGPL+ D W+ VGIVSWG CG P+ PGVYT
Sbjct: 363 QGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD-QWHVVGIVSWGYGCGGPSTPGVYTK 421
Query: 285 ISVYFHWIRRV 295
+S Y +WI V
Sbjct: 422 VSAYLNWIYNV 432
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 179 bits (455), Expect = 2e-45
Identities = 98/268 (36%), Positives = 148/268 (55%), Gaps = 20/268 (7%)
Query: 36 RPGGGGREEACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAH 95
R G CG + + + GG S+ G WPWQASL++R RH CGG+L++ RWV++AAH
Sbjct: 558 RDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAH 617
Query: 96 CFQKHYYPSE--WTVQLGELTSRPTPWNLRAYSSR--YKVQDIIVNPDALGVLRN-DIAL 150
CFQ+ S WTV LG++ W + +KV ++++P + D+AL
Sbjct: 618 CFQEDSMASTVLWTVFLGKV------WQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVAL 671
Query: 151 LRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTIL 210
L+L V +A ++P+C+ + + F CW+TGWG + G P L++ V ++
Sbjct: 672 LQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG---PISNALQKVDVQLI 728
Query: 211 NNTRCNYLFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDK-DGLWYQVGIVSW 269
C+ ++ R + M CAG G D C+GDSGGPLVC G W+ G+VSW
Sbjct: 729 PQDLCSEVY-----RYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSW 783
Query: 270 GMDCGQPNRPGVYTNISVYFHWIRRVMS 297
G+ CG+PN GVYT I+ WI++V++
Sbjct: 784 GLGCGRPNYFGVYTRITGVISWIQQVVT 811
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 175 bits (444), Expect = 4e-44
Identities = 91/259 (35%), Positives = 142/259 (54%), Gaps = 20/259 (7%)
Query: 45 ACG---HREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHY 101
ACG + + + GG + G WPWQ SL ++ H CGGS+++ W+++AAHC +K
Sbjct: 280 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 339
Query: 102 Y-PSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRN-DIALLRLASSVTY 159
P WT G L + Y + Y+V+ +I +P+ +N DIAL++L +T+
Sbjct: 340 NNPWHWTAFAGILRQ-----SFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTF 394
Query: 160 NAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCN--Y 217
N ++P+C+ + CW++GWG G L A+V ++ RCN Y
Sbjct: 395 NDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEV---LNAAKVLLIETQRCNSRY 451
Query: 218 LFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPN 277
+++ ++I +M CAG G+VD+C+GDSGGPLV K+ +W+ +G SWG C +
Sbjct: 452 VYD-----NLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAY 506
Query: 278 RPGVYTNISVYFHWIRRVM 296
RPGVY N+ V+ WI R M
Sbjct: 507 RPGVYGNVMVFTDWIYRQM 525
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 175 bits (444), Expect = 4e-44
Identities = 91/259 (35%), Positives = 142/259 (54%), Gaps = 20/259 (7%)
Query: 45 ACG---HREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHY 101
ACG + + + GG + G WPWQ SL ++ H CGGS+++ W+++AAHC +K
Sbjct: 243 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 302
Query: 102 Y-PSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRN-DIALLRLASSVTY 159
P WT G L + Y + Y+V+ +I +P+ +N DIAL++L +T+
Sbjct: 303 NNPWHWTAFAGILRQ-----SFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTF 357
Query: 160 NAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCN--Y 217
N ++P+C+ + CW++GWG G L A+V ++ RCN Y
Sbjct: 358 NDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEV---LNAAKVLLIETQRCNSRY 414
Query: 218 LFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPN 277
+++ ++I +M CAG G+VD+C+GDSGGPLV K+ +W+ +G SWG C +
Sbjct: 415 VYD-----NLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAY 469
Query: 278 RPGVYTNISVYFHWIRRVM 296
RPGVY N+ V+ WI R M
Sbjct: 470 RPGVYGNVMVFTDWIYRQM 488
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 174 bits (440), Expect = 1e-43
Identities = 97/261 (37%), Positives = 140/261 (53%), Gaps = 26/261 (9%)
Query: 44 EACGHR----EIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHC-FQ 98
++CG + +I + GG + G WPW L R CG SL+S W++SAAHC +
Sbjct: 770 KSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYG 829
Query: 99 KHYYPSEWTVQLG-----ELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLR-NDIALLR 152
++ PS+WT LG LTS T L + +I++NP + NDIA++
Sbjct: 830 RNLEPSKWTAILGLHMKSNLTSPQTVPRL--------IDEIVINPHYNRRRKDNDIAMMH 881
Query: 153 LASSVTYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNN 212
L V Y YIQPIC+ F +C + GWG + GT L+EA V +L+N
Sbjct: 882 LEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANI---LQEADVPLLSN 938
Query: 213 TRCNYLFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMD 272
RC +Q I ++M CAG E+G +D+C+GDSGGPL+C ++ W+ G+ S+G
Sbjct: 939 ERC----QQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYK 994
Query: 273 CGQPNRPGVYTNISVYFHWIR 293
C PNRPGVY +S + WI+
Sbjct: 995 CALPNRPGVYARVSRFTEWIQ 1015
>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
Length = 423
Score = 172 bits (435), Expect = 5e-43
Identities = 95/253 (37%), Positives = 137/253 (54%), Gaps = 19/253 (7%)
Query: 46 CGHREIHAL-----VAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKH 100
CG R L + GG E G WPWQASL+ HRCG +L++ W++SAAHCF +
Sbjct: 178 CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTY 237
Query: 101 YYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYN 160
P+ WT G +T +P+ ++ R V + +P DI+L L+S V Y
Sbjct: 238 KNPARWTASFG-VTIKPS--KMKRGLRRIIVHEKYKHPSH----DYDISLAELSSPVPYT 290
Query: 161 AYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFE 220
+ +C+ +++ F +VTG+G + G +LR+AQVT+++ T CN E
Sbjct: 291 NAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGY---SQNHLRQAQVTLIDATTCN---E 344
Query: 221 QPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLV-CDKDGLWYQVGIVSWGMDCGQPNRP 279
+ I M CAG+ +G D C+GDSGGPLV D +WY GIVSWG +C +PN+P
Sbjct: 345 PQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKP 404
Query: 280 GVYTNISVYFHWI 292
GVYT ++ WI
Sbjct: 405 GVYTRVTALRDWI 417
>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
Length = 423
Score = 172 bits (435), Expect = 5e-43
Identities = 95/253 (37%), Positives = 137/253 (54%), Gaps = 19/253 (7%)
Query: 46 CGHREIHAL-----VAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKH 100
CG R L + GG E G WPWQASL+ HRCG +L++ W++SAAHCF +
Sbjct: 178 CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTY 237
Query: 101 YYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYN 160
P+ WT G +T +P+ ++ R V + +P DI+L L+S V Y
Sbjct: 238 KNPARWTASFG-VTIKPS--KMKRGLRRIIVHEKYKHPSH----DYDISLAELSSPVPYT 290
Query: 161 AYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFE 220
+ +C+ +++ F +VTG+G + G +LR+AQVT+++ T CN E
Sbjct: 291 NAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGY---SQNHLRQAQVTLIDATTCN---E 344
Query: 221 QPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLV-CDKDGLWYQVGIVSWGMDCGQPNRP 279
+ I M CAG+ +G D C+GDSGGPLV D +WY GIVSWG +C +PN+P
Sbjct: 345 PQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKP 404
Query: 280 GVYTNISVYFHWI 292
GVYT ++ WI
Sbjct: 405 GVYTRVTALRDWI 417
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 171 bits (434), Expect = 6e-43
Identities = 94/246 (38%), Positives = 133/246 (54%), Gaps = 17/246 (6%)
Query: 55 VAGGVESARGRWPWQASLRLRRR---HRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLG 111
+ GG E+ R +WPWQ SLR+R R H CGGSL+ +WVL+AAHC L
Sbjct: 31 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPD------VKDLA 84
Query: 112 ELTSRPTPWNLRAYSSRYKVQDIIVNPDALGV-LRNDIALLRLASSVTYNAYIQPICIES 170
L + +L V IIV+P + DIALL L V ++++ + +
Sbjct: 85 ALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144
Query: 171 STFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRS---- 226
++ F CWVTGWG + + LPPP+ L++ +V I+ N C+ + +
Sbjct: 145 ASETFPPGMPCWVTGWGDVD-NDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203
Query: 227 MIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNIS 286
++ D M CAG + D+C+GDSGGPLVC +G W Q G+VSWG C QPNRPG+YT ++
Sbjct: 204 IVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261
Query: 287 VYFHWI 292
Y WI
Sbjct: 262 YYLDWI 267
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 171 bits (434), Expect = 6e-43
Identities = 92/241 (38%), Positives = 134/241 (55%), Gaps = 16/241 (6%)
Query: 54 LVAGGVESARGRWPWQASLRL-RRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGE 112
+V G + G WPWQASL+L H+CG SL+S W+L+AAHCF K+ P++W G
Sbjct: 206 IVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFGA 265
Query: 113 LTSRPTPWNLRAYSSRYKVQDIIVNPDA-LGVLRNDIALLRLASSVTYNAYIQPICIESS 171
+ P + + V+ II++ + NDIAL++L++ V ++ +Q +C+ S
Sbjct: 266 TITPP--------AVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDS 317
Query: 172 TFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDS 231
+ + +VTG+G I G P LR+A+V ++ CN + +I
Sbjct: 318 SIKLPPKTSVFVTGFGSIVDDG---PIQNTLRQARVETISTDVCN---RKDVYDGLITPG 371
Query: 232 MFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHW 291
M CAG +G +D CKGDSGGPLV D +WY VGIVSWG C P +PGVYT ++ Y W
Sbjct: 372 MLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDW 431
Query: 292 I 292
I
Sbjct: 432 I 432
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 171 bits (433), Expect = 8e-43
Identities = 95/251 (37%), Positives = 133/251 (52%), Gaps = 17/251 (6%)
Query: 46 CGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCF--QKHYYP 103
CG R + + GG ++ +WPWQ SL H CGG+L+ +WVL+AAHCF +
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376
Query: 104 SEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRN-DIALLRLASSVTYNAY 162
W V G TS NL + +II+N + + DIAL+RL+ +T +A+
Sbjct: 377 EGWKVYAG--TS-----NLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAH 429
Query: 163 IQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCN-YLFEQ 221
I P C+ F CW+TG+G + P LRE QV +++ +CN YL
Sbjct: 430 IHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSP--FLREVQVNLIDFKKCNDYLVYD 487
Query: 222 PSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGV 281
S + M CAG G D+C+GDSGGPLVC+++ WY G+ SWG CGQ N+PGV
Sbjct: 488 ----SYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGV 543
Query: 282 YTNISVYFHWI 292
YT ++ WI
Sbjct: 544 YTKVTEVLPWI 554
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 171 bits (432), Expect = 1e-42
Identities = 88/246 (35%), Positives = 134/246 (54%), Gaps = 23/246 (9%)
Query: 55 VAGGVESARGRWPWQASLRLR---RRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLG 111
+ GG S+ G WPWQ SL+++ +RH CGGSL+ +WVL+AAHCF W + G
Sbjct: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450
Query: 112 ELT----SRPTPWNLRAYSSRYKVQDIIVNPD-ALGVLRNDIALLRLASSVTYNAYIQPI 166
L ++ TP++ ++++II++ + + +DIAL++L + + Y + +PI
Sbjct: 451 ILNLSDITKDTPFS--------QIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502
Query: 167 CIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRS 226
C+ S +CWVTGWG G L++ + ++ N C ++
Sbjct: 503 CLPSKGDTSTIYTNCWVTGWGFSKEKGEI---QNILQKVNIPLVTNEECQKRYQDYK--- 556
Query: 227 MIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNIS 286
I M CAG ++G D CKGDSGGPLVC +G+W VGI SWG C + +PGVYT ++
Sbjct: 557 -ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA 615
Query: 287 VYFHWI 292
Y WI
Sbjct: 616 EYMDWI 621
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 169 bits (428), Expect = 3e-42
Identities = 94/247 (38%), Positives = 128/247 (51%), Gaps = 15/247 (6%)
Query: 50 EIHALVAGGVESARGRWPWQASLRLR---RRHRCGGSLLSRRWVLSAAHCFQKHYYPSEW 106
+I + GG S RG WPWQ +L +RH CGGS++ +W+L+AAHCF P
Sbjct: 383 KIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKIL 442
Query: 107 TVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPD-ALGVLRNDIALLRLASSVTYNAYIQP 165
V G L ++ +S + VQ+II++ + DIALL+L ++V Y +P
Sbjct: 443 RVYSGILNQS----EIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRP 498
Query: 166 ICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSR 225
IC+ S V DCWVTGWG L++A++ ++ N C +
Sbjct: 499 ICLPSKGDRNVIYTDCWVTGWGYRKLRDKI---QNTLQKAKIPLVTNEECQKRYRGHK-- 553
Query: 226 SMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNI 285
I M CAG +G D CKGDSGGPL C + +W+ VGI SWG C Q RPGVYTN+
Sbjct: 554 --ITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNV 611
Query: 286 SVYFHWI 292
Y WI
Sbjct: 612 VEYVDWI 618
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.462
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,699,967
Number of Sequences: 37866
Number of extensions: 739047
Number of successful extensions: 3153
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 179
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2487
Number of HSP's gapped (non-prelim): 252
length of query: 318
length of database: 18,247,518
effective HSP length: 102
effective length of query: 216
effective length of database: 14,385,186
effective search space: 3107200176
effective search space used: 3107200176
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.