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Search of human proteins with 203096856
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|203096856 kinesin family member 7 [Homo sapiens]
(1343 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|203096856 kinesin family member 7 [Homo sapiens] 2610 0.0
gi|30794488 kinesin family member 27 [Homo sapiens] 915 0.0
gi|83716024 kinesin family member 21B [Homo sapiens] 370 e-102
gi|38569484 kinesin family member 21A [Homo sapiens] 320 4e-87
gi|116686122 kinesin family member 4 [Homo sapiens] 308 2e-83
gi|150010604 kinesin family member 4B [Homo sapiens] 305 1e-82
gi|4758646 kinesin family member 3B [Homo sapiens] 254 3e-67
gi|41352705 kinesin family member 3C [Homo sapiens] 254 5e-67
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 244 4e-64
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 244 4e-64
gi|4758648 kinesin family member 5B [Homo sapiens] 243 9e-64
gi|46852174 kinesin family member 3A [Homo sapiens] 243 9e-64
gi|156616271 kinesin family member 19 [Homo sapiens] 243 1e-63
gi|45446749 kinesin family member 5A [Homo sapiens] 239 1e-62
gi|148612831 kinesin family member 18A [Homo sapiens] 232 2e-60
gi|4758650 kinesin family member 5C [Homo sapiens] 230 6e-60
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 227 5e-59
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 227 5e-59
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 227 5e-59
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 227 5e-59
gi|46852172 kinesin family member 13B [Homo sapiens] 226 9e-59
gi|122937289 kinesin family member 18B [Homo sapiens] 223 1e-57
gi|71061468 centromere protein E [Homo sapiens] 223 1e-57
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 221 3e-57
gi|13699824 kinesin family member 11 [Homo sapiens] 220 8e-57
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 212 2e-54
gi|7661878 kinesin family member 14 [Homo sapiens] 207 5e-53
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 207 5e-53
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 207 5e-53
gi|9910266 kinesin family member 15 [Homo sapiens] 207 5e-53
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 2610 bits (6765), Expect = 0.0
Identities = 1343/1343 (100%), Positives = 1343/1343 (100%)
Query: 1 MGLEAQRLPGAEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVV 60
MGLEAQRLPGAEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVV
Sbjct: 1 MGLEAQRLPGAEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVV 60
Query: 61 LAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIV 120
LAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIV
Sbjct: 61 LAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIV 120
Query: 121 PRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCG 180
PRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCG
Sbjct: 121 PRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCG 180
Query: 181 VKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAP 240
VKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAP
Sbjct: 181 VKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAP 240
Query: 241 GQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIP 300
GQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIP
Sbjct: 241 GQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIP 300
Query: 301 YRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPE 360
YRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPE
Sbjct: 301 YRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPE 360
Query: 361 AERPPEETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACTDAAY 420
AERPPEETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACTDAAY
Sbjct: 361 AERPPEETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACTDAAY 420
Query: 421 SLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVEDQAAQGAGGR 480
SLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVEDQAAQGAGGR
Sbjct: 421 SLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVEDQAAQGAGGR 480
Query: 481 KEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMVELRLRLEL 540
KEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMVELRLRLEL
Sbjct: 481 KEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMVELRLRLEL 540
Query: 541 VRPGWGGPRLLNGLPPGSFVPRPHTAPLGGAHAHVLGMVPPACLPGDEVGSEQRGEQVTN 600
VRPGWGGPRLLNGLPPGSFVPRPHTAPLGGAHAHVLGMVPPACLPGDEVGSEQRGEQVTN
Sbjct: 541 VRPGWGGPRLLNGLPPGSFVPRPHTAPLGGAHAHVLGMVPPACLPGDEVGSEQRGEQVTN 600
Query: 601 GREAGAELLTEVNRLGSGSSAASEEEEEEEEPPRRTLHLRRNRISNCSQRAGARPGSLPE 660
GREAGAELLTEVNRLGSGSSAASEEEEEEEEPPRRTLHLRRNRISNCSQRAGARPGSLPE
Sbjct: 601 GREAGAELLTEVNRLGSGSSAASEEEEEEEEPPRRTLHLRRNRISNCSQRAGARPGSLPE 660
Query: 661 RKGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRLAQAQQKIRELAINIRMK 720
RKGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRLAQAQQKIRELAINIRMK
Sbjct: 661 RKGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRLAQAQQKIRELAINIRMK 720
Query: 721 EELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGER 780
EELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGER
Sbjct: 721 EELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGER 780
Query: 781 SRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQR 840
SRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQR
Sbjct: 781 SRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQR 840
Query: 841 RLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVV 900
RLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVV
Sbjct: 841 RLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVV 900
Query: 901 SLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKR 960
SLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKR
Sbjct: 901 SLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKR 960
Query: 961 LRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQ 1020
LRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQ
Sbjct: 961 LRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQ 1020
Query: 1021 RLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQC 1080
RLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQC
Sbjct: 1021 RLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQC 1080
Query: 1081 EMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEV 1140
EMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEV
Sbjct: 1081 EMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEV 1140
Query: 1141 ALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRY 1200
ALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRY
Sbjct: 1141 ALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRY 1200
Query: 1201 MWINQELKQKLGGVNAVGHSRGGEKRSLCSEGRQAPGNEDELHLAPELLWLSPLTEGAPR 1260
MWINQELKQKLGGVNAVGHSRGGEKRSLCSEGRQAPGNEDELHLAPELLWLSPLTEGAPR
Sbjct: 1201 MWINQELKQKLGGVNAVGHSRGGEKRSLCSEGRQAPGNEDELHLAPELLWLSPLTEGAPR 1260
Query: 1261 TREETRDLVHAPLPLTWKRSSLCGEEQGSPEELRQREAAEPLVGRVLPVGEAGLPWNFGP 1320
TREETRDLVHAPLPLTWKRSSLCGEEQGSPEELRQREAAEPLVGRVLPVGEAGLPWNFGP
Sbjct: 1261 TREETRDLVHAPLPLTWKRSSLCGEEQGSPEELRQREAAEPLVGRVLPVGEAGLPWNFGP 1320
Query: 1321 LSKPRRELRRASPGMIDVRKNPL 1343
LSKPRRELRRASPGMIDVRKNPL
Sbjct: 1321 LSKPRRELRRASPGMIDVRKNPL 1343
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 915 bits (2364), Expect = 0.0
Identities = 581/1405 (41%), Positives = 846/1405 (60%), Gaps = 101/1405 (7%)
Query: 12 EEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVY 71
EE PV+VA+R+RPLL KE LH HQ C++V P +V +GRDR F F V +++ Q+ VY
Sbjct: 2 EEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVY 61
Query: 72 QACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEAFKLI 131
C++PL+ + EG+NATVFAYGQTGSGKTYT+G +AS++E ++GI+PRA+ E F+ I
Sbjct: 62 NTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQSI 121
Query: 132 DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDE 191
E+ +D V VSY+EVYKE+ RDLLE+ T+ +D+ +REDE+GN V+ G KE VE E
Sbjct: 122 SEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAGE 181
Query: 192 VLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPA--PGQLLVSKFH 249
V+SLLEMGNAARHTG T +N SSRSH +FT+++ Q + + + +VSKFH
Sbjct: 182 VMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFH 241
Query: 250 FVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRI 309
FVDLAGSERV KTG+TGER KESIQINS LLALGNVISALGDP+R+ SHIPYRD+KITR+
Sbjct: 242 FVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRL 301
Query: 310 LKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERPPEET- 368
LKDSLGG+AKTVMI CVSPSSS+FDE+LN+L YA+RA+NIRN+ TVN+ PE++R E
Sbjct: 302 LKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEF 361
Query: 369 -----ASGARGPPRHRSETRIIHR-GRRAPGPATASAAAAMRLGAECARYRACTDAAYSL 422
+ S+T I+R G + +L EC Y+ C + A++
Sbjct: 362 EIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTF 421
Query: 423 LRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVEDQAAQGAGGRKE 482
L +L+ L K+++W ++ R A+ ++ G S Q ++E
Sbjct: 422 LVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRE 481
Query: 483 DEGAQQLLT---------------LQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQ 527
+ Q +L L+NQV + +EN+ +L++A + +LQ++++ EQ
Sbjct: 482 LKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQ 541
Query: 528 Q-------EEMVELRLRLELVRPGWGGPRLLNGLPPGSFVP--RPHTAPLGGAHAHVLGM 578
Q EE+ +L L + + G P + +P RP+T P H + +
Sbjct: 542 QLLVDQLSEELTKLNLSVT------SSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYI 595
Query: 579 ----------VPPACLPGDEV--GSEQRGEQVTNGREAGAELLTEVNRLGSGSSAASEEE 626
P D + G R + + E ++L S S++E
Sbjct: 596 PSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLH------CQFSDNSDDE 649
Query: 627 EEEEEPPRRTLHLRRNRISNCSQRAGARPGSLPERKGPELCLEELDAAIPGSRAVGGSKA 686
E E + T R+ I S + + + LE D I +
Sbjct: 650 ESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQ------- 702
Query: 687 RVQARQVPPATASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIR 746
Q + SE L +A+QK+REL INI+MKE+LI EL++TG A+++++Q+S ++
Sbjct: 703 ESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVT 762
Query: 747 ELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQ-EFRRRVAAAQSQVQVLKEKKQ 805
+LE +AEQ + EL E Q+QL+ELE K+L D + +LQ EFR+++ AA+ +VQVL++K+Q
Sbjct: 763 KLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQ 822
Query: 806 ATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKE 865
+++L SLS Q+EKR ELE++V M+ Q+ QLQR+LREE E++++L+A + + Q ++KE
Sbjct: 823 DSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKE 882
Query: 866 LELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQ 925
++LK Q++ LK K E++ A KRR GS GS+ L QK++EQKKWLD+E+EKVL Q
Sbjct: 883 IQLKTGQEEG-LKPKAEDLDACNLKRRKGSFGSIDHL---QKLDEQKKWLDEEVEKVLNQ 938
Query: 926 RRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKEL 985
R+ LEEL +L KREAI++KKEAL+QEK+ LE+K+LRSSQALN D +++S+RL LE+EL
Sbjct: 939 RQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQEL 998
Query: 986 SEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQL 1045
SEK+ QL+ +A+ + +I +++ L++EKD L K+R +D KL+ G +LSPEEE LFQL
Sbjct: 999 SEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQL 1058
Query: 1046 DEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFD 1105
+E IEAL+AAIEY+NE+I RQ+ LRAS LS+ E N++ KL+ LS E R +L +YF+
Sbjct: 1059 EEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFN 1118
Query: 1106 KVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQ 1165
KVV LRE + +QQ+ E++M++ E+ +V LE AL+ +L+ DR+LTLQQKEHEQ MQ
Sbjct: 1119 KVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQ 1178
Query: 1166 LLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAVGHSRGGEK 1225
LLL ++ GEG+ ++ + YE +IQ LEK+L Y +++ K+KL VG + +
Sbjct: 1179 LLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKL--KELVGEA---IR 1233
Query: 1226 RSLCSEGRQAPGN-----EDELHLAPELLWLSPLTEGAPRTREETRD-----LVHAPLP- 1274
R L Q G+ E L+ EL W S RE D L P P
Sbjct: 1234 RQLAPSEYQEAGDGVLKPEGGGMLSEELKWASRPESMKLSGREREMDSSASSLRTQPNPQ 1293
Query: 1275 LTWK--------RSSLC--------GEEQGSPEELRQREAAEPLVGRVLPVGEAGLPWNF 1318
W+ SSL E + ++ + ++ L ++ VG G
Sbjct: 1294 KLWEDIPELPPIHSSLAPPSGHMLGNENKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGV 1353
Query: 1319 GPLSKPRRELRRASPGMIDVRKNPL 1343
P+ R+ELR+ S + +R++ L
Sbjct: 1354 TPVKLCRKELRQISALELSLRRSSL 1378
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 370 bits (951), Expect = e-102
Identities = 327/1173 (27%), Positives = 530/1173 (45%), Gaps = 159/1173 (13%)
Query: 8 LPGAEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQ 67
+ G + V+VA+R+RP L KE + G C V PG +V LG+D+ F + V D Q
Sbjct: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ 60
Query: 68 EAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEA 127
E +Y CV L+E FEG+NATV AYGQTG+GKTYTMG + E+EQGI+PRA+A
Sbjct: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
Query: 128 FKLIDENDLL---------DCLVHVSYLEVYKEEFRDLLEVGTASRD---------IQLR 169
F I E + V +LE+Y EE DL + ++RD I++
Sbjct: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFD---STRDPDTRHRRSNIKIH 177
Query: 170 EDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRG 229
ED G + GV + +E++ L+ G +R T +T +N SSRSH +FT+ L Q
Sbjct: 178 EDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMR 237
Query: 230 RA-------------PSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQIN 276
P P + + L +KFHFVDLAGSER+ +TG+TGER KE I IN
Sbjct: 238 MCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISIN 297
Query: 277 SSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDET 336
LLALGNVISALGD ++ H+PYRDSK+TR+L+DSLGGN++T+MIACVSPS DF ET
Sbjct: 298 CGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMET 357
Query: 337 LNTLNYASRAQNIRNRATVNWRPEAERPPEETASGARGPPRHRSETRIIHRGRRAPGPAT 396
LNTL YA+RA+NI+N+ VN ++ ++ ++ R + E G+R G
Sbjct: 358 LNTLKYANRARNIKNKVVVN----QDKTSQQISALRAEIARLQMELMEYKAGKRVIGED- 412
Query: 397 ASAAAAMRLGAECARYRACTDAAYS-LLRELQAEPGLPGAAARKVRDWLCAVEGERSALS 455
GAE YS L RE GA +V+ A++ + ++
Sbjct: 413 ---------GAE----------GYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVT 453
Query: 456 SASGPDSGIESASVEDQAAQGAGGRKEDEGAQQLLTLQNQVARLEEENRDFLAALEDAME 515
++ + A AG E GA +QN + +EE +
Sbjct: 454 QLMSQEANLLLAK--------AGDGNEAIGA----LIQNYIREIEE------------LR 489
Query: 516 QYKLQSDRLREQQEEMVELRLRLELVRPGWGGPRLLNGLPPGSFVPRPHTAP-LGGAHAH 574
L+S+ + E LR L R P L P AP GG+ A
Sbjct: 490 TKLLESEAMNES--------LRRSLSRASARSPYSLGASP---------AAPAFGGSPAS 532
Query: 575 VLGMVPPACLPGDEVGSEQRGEQVTNGREA-GAELLTEVNRLGSGSSAASEEEEEEEEPP 633
+ + + ++V R++ E + +L +S ++E E EEE
Sbjct: 533 SMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEE 592
Query: 634 RRTLHLRRNRISNCSQRAGARPGSLPERKGPELCLEELDAAIPGSRAVGGSKARVQARQV 693
R S C + G E G E L + D
Sbjct: 593 ERD-------ESGCEEEEGREDED--EDSGSEESLVDSD--------------------- 622
Query: 694 PPATASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAE 753
+ E + Q + +L I +K++LI EL + + Q L Q+ +++ L+
Sbjct: 623 ---SDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQ---N 676
Query: 754 QVRAELSEGQRQLRELEGKELQDAGERSRLQ-EFRRRVAAAQSQVQVLKEKKQATERLVS 812
++R E R L+ L E + ++++ ++ +R+ +Q L+ ++ RL+
Sbjct: 677 KIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLK 736
Query: 813 LSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLE-------AEMSKRQHR--- 862
++ E+ L++L+ V M++ + L +++REE +++R +E A++ K Q R
Sbjct: 737 NQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEF 796
Query: 863 -VKELELKHEQQQKILKIKTEEIAAFQR--KRRSGSNGSVVSLEQQQKIEEQKKWLDQEM 919
++ LE + QQ+ +L+ KT+E++A +R K S L+ +
Sbjct: 797 QIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTS 856
Query: 920 EKVLQQRRALEELGEELHKR-EAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRL 978
+ R++ + + +++ L A T K+ + A +
Sbjct: 857 SEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKW 916
Query: 979 EHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEE 1038
+ LE+ + + Q + + +++ L ++++ L + + K + SPEE
Sbjct: 917 QSLERRIIDIVMQ-----RMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEE 971
Query: 1039 ERTLFQLDEAIEALDAAIEYKNEAIT-CRQRVLRASASLLSQCEMNLMAKLSYLSSSETR 1097
E+ L +L E IE L A I+Y N+ IT C+ +++ + + +S S +E R
Sbjct: 972 EKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEAR 1031
Query: 1098 ALLCKYFDKVVTLREEQHQQQIAFSELEMQLEE 1130
LL + + + Q++ LE +L +
Sbjct: 1032 LLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQ 1064
Score = 50.8 bits (120), Expect = 9e-06
Identities = 157/739 (21%), Positives = 293/739 (39%), Gaps = 157/739 (21%)
Query: 482 EDEGAQQLLTLQNQVARLEEENRDFLAAL----EDAMEQYKLQSDRLREQ---QEEMVEL 534
+D+ +QQ+ L+ ++ARL+ E ++ A ED E Y SD RE Q+E L
Sbjct: 378 QDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGY---SDLFRENAMLQKENGAL 434
Query: 535 RLRLELVRPGWGGPRLLNGLPPGSFVPRPHTAPLGGAHAHVLGMVPPACLPGDEVGSEQR 594
RLR++ ++ +N L A++L GD G+E
Sbjct: 435 RLRVKAMQEAIDA---INN----------RVTQLMSQEANLL-----LAKAGD--GNEAI 474
Query: 595 GEQVTNGREAGAELLTEVNRLGSGSSAASEEEEEEEEPPRRTLHLRRNRISNCSQRAGAR 654
G + N EL T++ E E E RR+L RA AR
Sbjct: 475 GALIQNYIREIEELRTKLL-----------ESEAMNESLRRSL-----------SRASAR 512
Query: 655 -PGSLPERKGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRLAQAQQKIREL 713
P SL A P + A GGS PA++ E A + IR
Sbjct: 513 SPYSL--------------GASPAAPAFGGS----------PASSME----DASEVIR-- 542
Query: 714 AINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKE 773
R K++L + ++ QR + E+EA + RA+L + E E
Sbjct: 543 ----RAKQDL----------ERLKKKEVRQRRKSPEKEAFKKRAKLQQ--------ENSE 580
Query: 774 LQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQ 833
D E +E R + + + +++ +E + S+ +E E N Q
Sbjct: 581 ETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESL---VDSDSDPEEKEVNFQADLA 637
Query: 834 QQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKR-- 891
L E E K++L E+ Q R++ L+ ++E++ +L+ K + +R R
Sbjct: 638 D-------LTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRD-TQLERDRVL 689
Query: 892 RSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQ 951
++ S + E+ KI+ + +EM + LQ+ +A ++ L K ++ ++ +Q
Sbjct: 690 QNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQ 749
Query: 952 EKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLR 1011
+ ++ ++ AL + + R +E + + + QL++ + + QIR R
Sbjct: 750 AEV---AEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKR 806
Query: 1012 QEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCR-QRVL 1070
Q++ L ++ E+ R L P ER + LD+ E + +
Sbjct: 807 QQEMVLRRKTQEVSALRR---LAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGA 863
Query: 1071 RASASLLSQCEMNL---MAKLSYLSSSETRALLCKY--------FDKVVTLREEQHQ--- 1116
R+ +S++ Q + + + + TR K+ F K L+ + +
Sbjct: 864 RSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRI 923
Query: 1117 -----QQIAFSELEMQLE---EQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLL 1168
Q++ LE +E +++ ++ L+ AL R+R +L + E E+ +Q L
Sbjct: 924 IDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKR----ERLQAESPEEEKGLQELA 979
Query: 1169 QQ------SRDHLGEGLAD 1181
++ + D++ +G+ D
Sbjct: 980 EEIEVLAANIDYINDGITD 998
Score = 40.4 bits (93), Expect = 0.012
Identities = 99/497 (19%), Positives = 186/497 (37%), Gaps = 84/497 (16%)
Query: 750 QEAEQVRAELSEGQRQLRELE-GKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATE 808
Q+ +RAE++ Q +L E + GK + + R A Q + L+ + +A +
Sbjct: 383 QQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQ 442
Query: 809 RLVSLSAQSEKRLQELERNVQLMRQQQGQ------LQRRLREETEQKRRLEAEMSKRQHR 862
+ +L E N+ L + G +Q +RE E + +L + +
Sbjct: 443 EAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESL 502
Query: 863 VKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKV 922
+ L + L A S + S V +Q +E KK K
Sbjct: 503 RRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKK-------KE 555
Query: 923 LQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLE 982
++QRR E +EA KK A +Q++ E+ + + E
Sbjct: 556 VRQRRKSPE-------KEAF--KKRAKLQQENSEETDENEAEE----------------E 590
Query: 983 KELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTL 1042
+E ++SG + + + + G +SL + DS PEE+
Sbjct: 591 EEERDESGCEEEEGREDEDEDSGSEESL-VDSDS------------------DPEEKEVN 631
Query: 1043 FQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCK 1102
FQ D A L IE K + I + R +L Q E L+ + + ++
Sbjct: 632 FQADLA--DLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQ------- 682
Query: 1103 YFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQ 1162
L ++ Q + S +E EE+ + + E++ EM+R L Q ++
Sbjct: 683 -------LERDRVLQNL--STMECYTEEKANKI---KADYEKRLREMNRDLQKLQAAQKE 730
Query: 1163 NMQLLLQQSR-----DHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAV 1217
+ +LL QSR L +A+ ++ A ++ + +E R + + +++ +
Sbjct: 731 HARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKE 790
Query: 1218 GHSRGGEKRSLCSEGRQ 1234
+ + R+L S+ RQ
Sbjct: 791 QRRQEFQIRALESQKRQ 807
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 320 bits (821), Expect = 4e-87
Identities = 175/377 (46%), Positives = 237/377 (62%), Gaps = 28/377 (7%)
Query: 8 LPGAEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQ 67
L +E+ VRVA+R+RP L KE + G C V PG +V LG+D+ F F V D+ Q
Sbjct: 2 LGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQ 61
Query: 68 EAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEA 127
E +Y C++ L+E FEG+NATVFAYGQTG+GKTYTMG +++E+E GI+ RA+
Sbjct: 62 EQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHL 121
Query: 128 FKLIDENDLL---------DCLVHVSYLEVYKEEFRDL------LEVGTASRDIQLREDE 172
FK I+E + D V+ +LE+Y EE DL ++ + +I++ ED
Sbjct: 122 FKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDS 181
Query: 173 RGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAP 232
G + GV V E++ L++G +R T +T +N SSRSH +FT+ + Q P
Sbjct: 182 TGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCP 241
Query: 233 -------------SRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSL 279
S + + L +KFHFVDLAGSER+ +TG+TGER KE I IN L
Sbjct: 242 QIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 301
Query: 280 LALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNT 339
LALGNVISALGD +R +H+PYRDSK+TR+L+DSLGGN++T+MIACVSPS DF ETLNT
Sbjct: 302 LALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 361
Query: 340 LNYASRAQNIRNRATVN 356
L YA+RA+NI+N+ VN
Sbjct: 362 LKYANRARNIKNKVMVN 378
Score = 103 bits (256), Expect = 1e-21
Identities = 88/446 (19%), Positives = 213/446 (47%), Gaps = 30/446 (6%)
Query: 704 AQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
A Q + + I +K++LI EL + K Q L +Q+ +++ L+ + + E +
Sbjct: 628 ANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVL 687
Query: 764 RQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQE 823
+ L +E + A + E+ +++ A ++Q L+ ++ RL+ +Q EK+L++
Sbjct: 688 QNLGSVESYSEEKA--KKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKK 745
Query: 824 LERNVQLMRQQQGQLQRRLREETEQKR-----------RLEAEMSKRQHRVKELELKHEQ 872
L+++V M++ + +L ++++EE E+ R +L+ + KR H+++ LE +
Sbjct: 746 LQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRN 805
Query: 873 QQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEEL 932
Q+ +L+ KTEE+ A +R+ R S+ + K+ + D + A+E
Sbjct: 806 QEVVLRRKTEEVTALRRQVRPMSD------KVAGKVTRKLSSSDAPAQDTGSSAAAVETD 859
Query: 933 GEEL---HKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRL--EHLEKELSE 987
K +A+ +AL T K+ + + ++R+ + LE+ +++
Sbjct: 860 ASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTD 919
Query: 988 KSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDE 1047
Q + + +++ L ++++ L K+R ++ + + + E ++ + ++E
Sbjct: 920 IIMQ-----KMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINE 974
Query: 1048 AIEALDAAIEYKNEAIT-CRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDK 1106
+E+L A I+Y N++I+ C+ +++ + +++ A ++ + +E R LL +
Sbjct: 975 EMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSM 1034
Query: 1107 VVTLREEQHQQQIAFSELEMQLEEQQ 1132
+ + Q++ LE +L++ +
Sbjct: 1035 GINKGLQAAQKEAQIKVLEGRLKQTE 1060
Score = 47.0 bits (110), Expect = 1e-04
Identities = 59/335 (17%), Positives = 144/335 (42%), Gaps = 23/335 (6%)
Query: 704 AQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
A Q + L + I+ +E + L + Q ++ Q + + + E++ +
Sbjct: 426 AMLQTENNNLRVRIKAMQETVDAL--RSRITQLVSDQANHVLARAGEGNEEISNMIHSYI 483
Query: 764 RQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQ--------VLKEKKQATERLVSLSA 815
+++ +L K L+ L++ R A +L K+ E ++ L+
Sbjct: 484 KEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIE-IIDLAK 542
Query: 816 QSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQK 875
+ ++L+ E+ R+++ + +T+Q+++ E +S+R++ ELE++ Q+
Sbjct: 543 KDLEKLKRKEK-----RKKKSVAGKEDNTDTDQEKKEEKGVSERENN--ELEVEESQEVS 595
Query: 876 ILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEE 935
+ + EE + G + E +K Q + E ++Q+ ++EL E
Sbjct: 596 DHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQK-LIDEL-EN 653
Query: 936 LHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQG 995
KR L K+ +EK + ++R +Q + +++ +E +E ++K +
Sbjct: 654 SQKRLQTLKKQ---YEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEK 710
Query: 996 SAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQ 1030
Q+ + + + ++E LLK + + + +L++
Sbjct: 711 KLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKK 745
Score = 30.8 bits (68), Expect = 9.1
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 1127 QLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQY 1186
+LE Q+ + L+ E + + + ++ Q E +Q +Q L + E R +Y
Sbjct: 650 ELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNL-GSVESYSEEKAKKVRSEY 708
Query: 1187 EARIQALEKELGRYMWINQE 1206
E ++QA+ KEL R +E
Sbjct: 709 EKKLQAMNKELQRLQAAQKE 728
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 308 bits (789), Expect = 2e-83
Identities = 169/347 (48%), Positives = 220/347 (63%), Gaps = 9/347 (2%)
Query: 15 PVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQAC 74
PVRVALR RPL+PKE+ G Q CL PG +V +G D+ F + V QE V+
Sbjct: 9 PVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTA 68
Query: 75 VQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASL-LEDEQGIVPRAMAEAFKLIDE 133
V PL++ F+G+NATV AYGQTGSGKTY+MG A A E G++PR + FK ID+
Sbjct: 69 VAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDK 128
Query: 134 NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDEVL 193
+ + VSYLE+Y EE DLL I +RED + + + G+ E V + +
Sbjct: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
Query: 194 SLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSKFHFVDL 253
S LE GN +R +T +N SSRSH +FT++LEQR ++ SK H VDL
Sbjct: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDK-------NSSFRSKLHLVDL 241
Query: 254 AGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDS 313
AGSER KT + G+RLKE I IN LL LGNVISALGD ++G +PYRDSK+TR+L+DS
Sbjct: 242 AGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-DKKGGFVPYRDSKLTRLLQDS 300
Query: 314 LGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPE 360
LGGN+ T+MIACVSP+ S+ +ETLNTL YA RA+ I+N+ VN P+
Sbjct: 301 LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQ 347
Score = 116 bits (290), Expect = 2e-25
Identities = 117/517 (22%), Positives = 236/517 (45%), Gaps = 78/517 (15%)
Query: 702 RLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSE 761
R AQ +++ EL + +KE L ++ + Q + Q+ I+ELE E ++ E E
Sbjct: 518 RQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEE 577
Query: 762 GQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRL 821
+L+ + +DA + + R+R+ + Q+ LK+K +L+ L +E+ +
Sbjct: 578 LVLELQTAK----KDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTV 633
Query: 822 QELERNVQLMRQQQGQLQRRLREETEQKR-----------RLEAEMSKRQHRVKELELKH 870
+L + +++M+ Q+ QL R+++E+ E+ R +L+ KRQ+ + +LE
Sbjct: 634 SKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNF 693
Query: 871 EQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKK----------------W 914
++Q +L+ KTEE AA ++ + +L++Q+++ +++K W
Sbjct: 694 QKQSNVLRRKTEEAAAANKRLKD-------ALQKQREVADKRKETQSRGMEGTAARVKNW 746
Query: 915 LDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEK-------------TGLESKRL 961
L E+E ++ A L + L R+ ILA+ A ++EK +
Sbjct: 747 LGNEIEVMVSTEEAKRHLNDLLEDRK-ILAQDVAQLKEKKESGENPPPKLRRRTFSLTEV 805
Query: 962 RSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQR 1021
R + +ED ++ ++E LE E+ +S Q+ A QQ++ L E + KQR
Sbjct: 806 RGQVSESED--SITKQIESLETEMEFRSAQI----ADLQQKL------LDAESEDRPKQR 853
Query: 1022 LEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCE 1081
E + + L + L+++++ + Q++L + ++ E
Sbjct: 854 WENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIE 913
Query: 1082 MNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQL-EEQQRLVYWL-- 1138
L A+L + ++ +KV+ L + Q Q+A +LE + E++Q+L+ L
Sbjct: 914 TELQAELVRMEQ--------QHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKC 965
Query: 1139 ---EVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSR 1172
E+ R+ E ++QL + + +Q + LL SR
Sbjct: 966 QDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASR 1002
Score = 56.2 bits (134), Expect = 2e-07
Identities = 107/588 (18%), Positives = 238/588 (40%), Gaps = 121/588 (20%)
Query: 731 GKAAQALNR-----QHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGER-SRLQ 784
G+ AQ L R Q ++++ +E Q A + Q+ + LE +EL++ E LQ
Sbjct: 411 GQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQ 470
Query: 785 EFRRRV--------AAA-------QSQVQVLKEKKQATERLVSL----SAQSEKRLQELE 825
+ ++ AAA ++QV+ E ++++ + AQ K L EL
Sbjct: 471 QLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELN 530
Query: 826 RNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELE-----LKHEQQQKILKIK 880
+ + L + R+ T+ +L+ + Q +KELE L+ E+++ +L+++
Sbjct: 531 KALALK-------EALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQ 583
Query: 881 TEEIAAFQ-------RKRRSGSNGSVVSLEQQQKIEEQKKW-------------LDQEME 920
T + A Q RKR G + L ++K+ EQ K L+QE+
Sbjct: 584 TAKKDANQAKLSERRRKRLQELEGQIADL--KKKLNEQSKLLKLKESTERTVSKLNQEIR 641
Query: 921 KVLQQR----------------------RALEELGEELHKREAILAKKEALMQEKTGLES 958
+ QR + + +L E KR+ L K E Q+++ +
Sbjct: 642 MMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLR 701
Query: 959 KRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQ--------------SQQQIR 1004
++ + A N+ + + + + E + +G+A S ++ +
Sbjct: 702 RKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAK 761
Query: 1005 GEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEA--------------IE 1050
++ L +++ L + ++ K G P+ R F L E IE
Sbjct: 762 RHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIE 821
Query: 1051 ALDAAIEYKNEAIT-CRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVT 1109
+L+ +E+++ I +Q++L A + + +A + E + L ++V+
Sbjct: 822 SLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATI-----LEAKCALKYLIGELVS 876
Query: 1110 LREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLL- 1168
+ + + + + + + + Q++++ E+ +L +++H++ + LL
Sbjct: 877 SKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLS 936
Query: 1169 -----QQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKL 1211
Q + L E +++ +Q + ++ ++EL + + ++ +Q L
Sbjct: 937 QLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLL 984
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 305 bits (782), Expect = 1e-82
Identities = 169/346 (48%), Positives = 220/346 (63%), Gaps = 9/346 (2%)
Query: 15 PVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQAC 74
PVRVALR RPL+PKE+ G Q CL PG +V +G D+ F + V QE V+
Sbjct: 9 PVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKA 68
Query: 75 VQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASL-LEDEQGIVPRAMAEAFKLIDE 133
V PL++ F+G+NATV AYGQTGSGKTY+MG A A E GI+PR + FK ID+
Sbjct: 69 VAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEIDK 128
Query: 134 NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDEVL 193
+ + VSYLE+Y EE DLL I +RED + + + G+ E V + +
Sbjct: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
Query: 194 SLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSKFHFVDL 253
S LE GN +R +T +N SSRSH +FT+++EQR ++ SK H VDL
Sbjct: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCS-------FRSKLHLVDL 241
Query: 254 AGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDS 313
AGSER KT + G+RLKE I IN LL LGNVISALGD ++GS +PYRDSK+TR+L+DS
Sbjct: 242 AGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-DKKGSFVPYRDSKLTRLLQDS 300
Query: 314 LGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRP 359
LGGN+ T+MIACVSP+ S+ +ETL+TL YA RA+ I+N+ VN P
Sbjct: 301 LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDP 346
Score = 111 bits (278), Expect = 4e-24
Identities = 122/528 (23%), Positives = 244/528 (46%), Gaps = 75/528 (14%)
Query: 704 AQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
AQ +++ EL + +KE L+ ++ + Q + Q+ I+ LE E ++ E E
Sbjct: 520 AQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELV 579
Query: 764 RQLRELEGKELQDAGERSRLQEFRRRVAAA-QSQVQVLKEKKQATERLVSLSAQSEKRLQ 822
R+L+ + Q ++L E R ++ + Q+ LK+K +L+ L +E+ +
Sbjct: 580 RELQTAKKNVNQ-----AKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVS 634
Query: 823 ELERNVQLMRQQQGQLQRRLREETEQKRR-----------LEAEMSKRQHRVKELELKHE 871
+L + + +M+ Q+ QL R+++E+ E+ R+ L+ KRQ+ + +LE +
Sbjct: 635 KLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQ 694
Query: 872 QQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEE 931
+Q +L+ KTEE AA ++ + +L++Q+++ +++K ++ + R
Sbjct: 695 KQSSVLRRKTEEAAAANKRLKD-------ALQKQREVTDKRKETQSHGKEGI-AARVRNW 746
Query: 932 LGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEK-------- 983
LG E+ E +++ +EA LE +++ L +D+V++ + E E
Sbjct: 747 LGNEI---EVMVSTEEAKRHLNDLLEDRKI-----LAQDVVQLKEKKESRENPPPKLRKC 798
Query: 984 --ELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEER- 1040
LSE GQ+ +S+ I +I+SL E + Q ++ KL L + E+R
Sbjct: 799 TFSLSEVHGQV----LESEDCITKQIESLETEMELRSAQIADLQQKL----LDAESEDRP 850
Query: 1041 --------TLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLS 1092
T+ + A++ L + +T + LR S + + + L + ++ S
Sbjct: 851 KQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFS 910
Query: 1093 SSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQ 1152
ET + E+QHQ+++ + L QL+E Q E LE+ E ++Q
Sbjct: 911 EIETE------LQAELVRMEQQHQEKVLY--LVSQLQESQ----MAEKQLEKSASEKEQQ 958
Query: 1153 L--TLQ-QKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKEL 1197
L TLQ Q E + M+ + +Q++ L E ++ ++ + +K L
Sbjct: 959 LVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQKHL 1006
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 254 bits (650), Expect = 3e-67
Identities = 184/526 (34%), Positives = 270/526 (51%), Gaps = 32/526 (6%)
Query: 16 VRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRH--------FGFHVVLAEDAGQ 67
VRV +R RP+ KE + + V+ LG+V++ + F F V +A Q
Sbjct: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
Query: 68 EAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEA 127
+Y +PL+++ +GFN T+FAYGQTG+GKTYTM +++G++P +
Sbjct: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDP---EKRGVIPNSFDHI 126
Query: 128 FKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 187
F I + LV SYLE+Y+EE RDLL R ++L+E V + + +
Sbjct: 127 FTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKR-LELKERPDTGVYVKDLSSFVTK 185
Query: 188 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSK 247
+ E+ ++ +GN R GAT++N SSRSH +F +T+E S + + V K
Sbjct: 186 SVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIEC-----SEVGLDGENHIRVGK 240
Query: 248 FHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKIT 307
+ VDLAGSER KTG+ GERLKE+ +IN SL ALGNVISAL D + +HIPYRDSK+T
Sbjct: 241 LNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDG--KSTHIPYRDSKLT 298
Query: 308 RILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAE--RPP 365
R+L+DSLGGNAKTVM+A V P+S + +ETL TL YA+RA+NI+N+ VN P+ R
Sbjct: 299 RLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREF 358
Query: 366 EETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACTDAAYSLLRE 425
+E + + RS R R +R G + E D RE
Sbjct: 359 QEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEG--DDKDDYWRE 416
Query: 426 LQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVEDQAAQGAGGRKEDEG 485
Q + + A V D E + L + +E E AA+ G + +
Sbjct: 417 QQEKLEIEKRAI--VEDHSLVAEEKMRLLKE---KEKKMEDLRREKDAAEMLGAKIKAME 471
Query: 486 AQQLLTLQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEM 531
++ L+ +N V E+ + LE ++ Q R RE Q++M
Sbjct: 472 SKLLVGGKNIVDHTNEQQK----ILEQKRQEIAEQKRREREIQQQM 513
Score = 46.6 bits (109), Expect = 2e-04
Identities = 74/368 (20%), Positives = 158/368 (42%), Gaps = 73/368 (19%)
Query: 745 IRELEQEAEQVRAELSE---GQRQLREL----------------EGKELQDAGE------ 779
+RE ++E +++A+L + G+R+ RE EG+E ++ G+
Sbjct: 355 LREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYW 414
Query: 780 ---RSRLQEFRRRVA-----AAQSQVQVLKEK----------KQATERL-VSLSAQSEKR 820
+ +L+ +R + A+ ++++LKEK K A E L + A K
Sbjct: 415 REQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKL 474
Query: 821 LQELERNVQLMRQQQGQLQRRLREETEQKRR---LEAEMSKRQHRVKELELKHEQQQKIL 877
L + V +QQ L+++ +E EQKRR ++ +M R EL+ + Q+ +
Sbjct: 475 LVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEV 534
Query: 878 KIKTEEI----AAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEM-------------- 919
IKT+++ + Q + + ++++Q++E+ + L +E+
Sbjct: 535 DIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLE 594
Query: 920 EKVLQQRRALEELGEELHKREAI--LAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSR 977
EK RA + E+ K I L ++ + + + + KR S A ++R +R
Sbjct: 595 EKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEAR 654
Query: 978 -----LEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGS 1032
+ LE ++ ++ + +G A + +++ +D+ Q++D + + + S
Sbjct: 655 YRAENIVLLELDMPSRTTRDYEGPAIA-PKVQAALDAALQDEDEIQVDASSFESTANKKS 713
Query: 1033 LLSPEEER 1040
P+ R
Sbjct: 714 KARPKSGR 721
Score = 35.4 bits (80), Expect = 0.37
Identities = 61/296 (20%), Positives = 115/296 (38%), Gaps = 31/296 (10%)
Query: 602 REAGAELLTEVNRLGSGSSAASEEEEEE-----EEPPRRTLHLRRNRIS-NCSQRAGARP 655
R G E R G GS EEEEEE EE + + R + +RA
Sbjct: 372 RSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVED 431
Query: 656 GSL-----------PERKGPELCLEELDAAIPGSRAVG-GSKARVQARQVPPATASEWRL 703
SL E+K +L E+ A + G++ SK V + + T + ++
Sbjct: 432 HSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKI 491
Query: 704 AQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
+ QK +E+A R + E+ ++ + L +S +E++ + ++++ S+ Q
Sbjct: 492 LE--QKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQ 549
Query: 764 RQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQV-------LKEKKQATERLVSLSAQ 816
E+ + + ER L++ + + + L+EK + R +
Sbjct: 550 AVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEE 609
Query: 817 SEKRLQELER--NVQLMRQQQGQL--QRRLREETEQKRRLEAEMSKRQHRVKELEL 868
+L + R N Q+M++ + +R L + + E R + LEL
Sbjct: 610 DHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLEL 665
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 254 bits (648), Expect = 5e-67
Identities = 186/555 (33%), Positives = 270/555 (48%), Gaps = 95/555 (17%)
Query: 11 AEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRH--------FGFHVVLA 62
A EA ++V R RPL KE GH+ L ++ LG+VTL R F F V
Sbjct: 7 ASEA-LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYD 65
Query: 63 EDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPR 122
+ Q +Y V+PL+++ +GFN TVFAYGQTG+GKTYTM V L +G++P
Sbjct: 66 ASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPEL---RGVIPN 122
Query: 123 AMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVK 182
A F I + LV SYLE+Y+EE RDLL R ++L+E+ V + +
Sbjct: 123 AFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKR-LELKENPETGVYIKDLS 181
Query: 183 EVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQ 242
+ + E+ ++ +GN R G+TH+N +SSRSH +F +T+E R
Sbjct: 182 SFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSD-----GQDH 236
Query: 243 LLVSKFHFVDLAGSERVLKTGST------------------------GERLKESIQINSS 278
+ V K + VDLAGSER K G GER KE+ +IN S
Sbjct: 237 IRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLS 296
Query: 279 LLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLN 338
L ALGNVI+AL R +HIPYRDSK+TR+L+DSLGGNAKT+M+A + P+S +DE+L+
Sbjct: 297 LSALGNVIAALAG--NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLS 354
Query: 339 TLNYASRAQNIRNRATVNWRPEAERPPEETASGARGPPRHRSETRIIHRGRRAPGPATAS 398
TL +A+RA+NI+N+ VN P++T R + ++ RG P S
Sbjct: 355 TLRFANRAKNIKNKPRVN------EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKS 408
Query: 399 AAAAMRLGAECARYRACTDAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSAS 458
+ + + A PG P + W+ E + + ++
Sbjct: 409 SRRK---------------------KAVSAPPGYPEGPV--IEAWVAEEEDDNN--NNHR 443
Query: 459 GPDSGIESASVEDQAAQGAGGRKEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYK 518
P +ESA ++ LQ Q RLEEE AA++D
Sbjct: 444 PPQPILESALEKNMENY----------------LQEQKERLEEEK----AAIQDDRSLVS 483
Query: 519 LQSDRLREQQEEMVE 533
+ +L E++E+M+E
Sbjct: 484 EEKQKLLEEKEKMLE 498
Score = 46.6 bits (109), Expect = 2e-04
Identities = 41/158 (25%), Positives = 76/158 (48%), Gaps = 7/158 (4%)
Query: 738 NRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQV 797
N H LE E+ + Q++ E E +QD +RS + E ++++ + ++
Sbjct: 439 NNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQD--DRSLVSEEKQKLLEEKEKM 496
Query: 798 -QVLKEKKQATERLVSLSAQSEKRLQELERNV-QLMRQQQGQLQRRLREETEQKRR---L 852
+ L+ ++QATE L + E +L RN+ +QQ L+ + +E EQKRR +
Sbjct: 497 LEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREM 556
Query: 853 EAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRK 890
+ EM R EL + Q+ +++KT+++ K
Sbjct: 557 QQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAK 594
Score = 38.9 bits (89), Expect = 0.034
Identities = 43/178 (24%), Positives = 79/178 (44%), Gaps = 23/178 (12%)
Query: 794 QSQVQVLKEKKQATERLVSL-SAQSEKRLQELERNVQ-LMRQQQGQLQRRLREETEQKRR 851
Q Q + L+E+K A + SL S + +K L+E E+ ++ L R+QQ + + + +
Sbjct: 462 QEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKL 521
Query: 852 LEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQ 911
L + H +QQK+L++K +EIA +R+ R ++ E+ ++
Sbjct: 522 LIGGRNIMDHT--------NEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGT 573
Query: 912 KKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNE 969
L QE+E + K + + AK +A+ E + +R Q L E
Sbjct: 574 YTSLQQEVE-------------VKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEE 618
Score = 35.4 bits (80), Expect = 0.37
Identities = 31/158 (19%), Positives = 73/158 (46%), Gaps = 3/158 (1%)
Query: 720 KEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGE 779
KE+++ +L R +A + L ++ +L + +E Q+ L EL+ +E+ +
Sbjct: 493 KEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKML-ELKRQEIAEQKR 551
Query: 780 RSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQ 839
R R E ++ + + L+ + ++ V + + K+L + V+ Q Q
Sbjct: 552 RER--EMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEY 609
Query: 840 RRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKIL 877
R+R++ E+ + + K ++ + E + E++ KI+
Sbjct: 610 IRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIM 647
Score = 30.8 bits (68), Expect = 9.1
Identities = 46/226 (20%), Positives = 95/226 (42%), Gaps = 54/226 (23%)
Query: 847 EQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRS------------- 893
EQK RLE E + Q + L E++QK+L+ K + + +R++++
Sbjct: 463 EQKERLEEEKAAIQD---DRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMES 519
Query: 894 -----GSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEA 948
G N + EQQ+ +E ++ +++ +Q+R E+ +E+ R+
Sbjct: 520 KLLIGGRNIMDHTNEQQKMLELKR-------QEIAEQKRREREMQQEMMLRDE------- 565
Query: 949 LMQEKTGLESKRLRSS-QALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEI 1007
E+ LR + +L +++ + +L+ L +L ++ Q ++R ++
Sbjct: 566 --------ETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEI-QDQHDEYIRVRQDL 616
Query: 1008 DSLRQEKDSLLKQRL---------EIDGKLRQGSLLSPEEERTLFQ 1044
+ + E+ LK + E K+ L EEE+ FQ
Sbjct: 617 EEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQ 662
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 244 bits (623), Expect = 4e-64
Identities = 150/358 (41%), Positives = 211/358 (58%), Gaps = 21/358 (5%)
Query: 11 AEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRD-------RHFGFHVVLAE 63
A EA V+V +R RP+ +E Q + V+ + + + F F
Sbjct: 2 ASEA-VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHV 60
Query: 64 DAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLLEDEQGIVPR 122
D E +Y PL+E EG+N T+FAYGQTGSGK++TM G S ++GI+PR
Sbjct: 61 DHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPS----QRGIIPR 116
Query: 123 AMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVK 182
A F+ + + LV SYLE+Y E+ RDLL T + ++L+E V + G+
Sbjct: 117 AFEHVFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQK-LELKEHPEKGVYVKGLS 175
Query: 183 EVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQ 242
V + + ++E G R G T +N SSRSH++FT+++E S +
Sbjct: 176 MHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEM-----SAVDERGKDH 230
Query: 243 LLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYR 302
L K + VDLAGSER KTG+TGERLKE+ +IN SL ALGNVISAL D R H+PYR
Sbjct: 231 LRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDG--RCKHVPYR 288
Query: 303 DSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPE 360
DSK+TR+L+DSLGGN KT+M+AC+SP+ +++DETL+TL YA+RA+NIRN+ +N P+
Sbjct: 289 DSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPK 346
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 244 bits (623), Expect = 4e-64
Identities = 150/358 (41%), Positives = 211/358 (58%), Gaps = 21/358 (5%)
Query: 11 AEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRD-------RHFGFHVVLAE 63
A EA V+V +R RP+ +E Q + V+ + + + F F
Sbjct: 2 ASEA-VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHV 60
Query: 64 DAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLLEDEQGIVPR 122
D E +Y PL+E EG+N T+FAYGQTGSGK++TM G S ++GI+PR
Sbjct: 61 DHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPS----QRGIIPR 116
Query: 123 AMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVK 182
A F+ + + LV SYLE+Y E+ RDLL T + ++L+E V + G+
Sbjct: 117 AFEHVFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQK-LELKEHPEKGVYVKGLS 175
Query: 183 EVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQ 242
V + + ++E G R G T +N SSRSH++FT+++E S +
Sbjct: 176 MHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEM-----SAVDERGKDH 230
Query: 243 LLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYR 302
L K + VDLAGSER KTG+TGERLKE+ +IN SL ALGNVISAL D R H+PYR
Sbjct: 231 LRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDG--RCKHVPYR 288
Query: 303 DSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPE 360
DSK+TR+L+DSLGGN KT+M+AC+SP+ +++DETL+TL YA+RA+NIRN+ +N P+
Sbjct: 289 DSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPK 346
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 243 bits (620), Expect = 9e-64
Identities = 264/1027 (25%), Positives = 451/1027 (43%), Gaps = 142/1027 (13%)
Query: 13 EAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQ 72
E ++V R RPL E+ G + + + G V + + + F V QE VY
Sbjct: 6 ECNIKVMCRFRPLNESEVNRGDKYIAKFQ-GEDTVVIA-SKPYAFDRVFQSSTSQEQVYN 63
Query: 73 ACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQG--IVPRAMAEAFKL 130
C + +++ EG+N T+FAYGQT SGKT+TM L D +G I+PR + + F
Sbjct: 64 DCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTM-----EGKLHDPEGMGIIPRIVQDIFNY 118
Query: 131 I---DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 187
I DEN L+ + VSY E+Y ++ RDLL+V + ++ + ED+ + G E V
Sbjct: 119 IYSMDEN--LEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDKNRVPYVKGCTERFVC 174
Query: 188 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSK 247
DEV+ ++ G + RH T++N SSRSH++F + ++Q Q L K
Sbjct: 175 SPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTE--------QKLSGK 226
Query: 248 FHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKIT 307
+ VDLAGSE+V KTG+ G L E+ IN SL ALGNVISAL + +++PYRDSK+T
Sbjct: 227 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS---TYVPYRDSKMT 283
Query: 308 RILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN-------WRPE 360
RIL+DSLGGN +T ++ C SPSS + ET +TL + RA+ I+N VN W+ +
Sbjct: 284 RILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKK 343
Query: 361 AERPPEETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACT-DAA 419
E+ E+ +E G P + E A A T D
Sbjct: 344 YEKEKEKNKILRNTIQWLENELNRWRNGETVP--------IDEQFDKEKANLEAFTVDKD 395
Query: 420 YSLLRELQAEP-GLPG----AAARKVRDWLC----AVEGERSALSSASGPDSGIESASVE 470
+L + A G+ G A RK + + ++ + ++ S +++ ++
Sbjct: 396 ITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLD 455
Query: 471 DQAAQGAGGRKEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEE 530
+ + R +D +L LQ + +EE ++ L ALE+ Y +S + ++ +E
Sbjct: 456 QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKE 515
Query: 531 MVELRLRLELVRPGWGGPRLLNGLPPGSFVPRPHTAPLGGAHAHVLGMVPPACLPGDEVG 590
L L +A L A + +
Sbjct: 516 YELLSDEL-----------------------NQKSATLASIDAELQKL------------ 540
Query: 591 SEQRGEQVTNGREAGAELLTEVNRLG--SGSSAASEEE-----EEEEEPPRRTLHLRRNR 643
E Q E A LL ++ +G G++ + E +EE R + ++
Sbjct: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600
Query: 644 ISNCSQRAGARPGSLPERKGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRL 703
+ +R + E +EE + + + R+ + + +E+ L
Sbjct: 601 VKTMVKRCKQLESTQTESNKK---MEE------NEKELAACQLRISQHEAKIKSLTEY-L 650
Query: 704 AQAQQKIRELAINI-RMKEELIGELVRTGKAAQALNRQHSQRIR---ELEQEAE-QVRAE 758
+QK R+L ++ + EEL+ +R + + ++H +++ E++Q E Q+++
Sbjct: 651 QNVEQKKRQLEESVDALSEELV--QLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSH 708
Query: 759 LSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSE 818
Q+Q+ L + A + LQ+ +++ Q +++V EK +AT++ +
Sbjct: 709 RETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQ------EKS 762
Query: 819 KRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILK 878
++L EL V R++Q + + EET KEL+ H + K
Sbjct: 763 RKLHEL--TVMQDRREQARQDLKGLEETV---------------AKELQTLH----NLRK 801
Query: 879 IKTEEIAAFQRKRRS-GSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELH 937
+ +++A +K S+ + S Q+QKI + L+Q + Q R +L EL
Sbjct: 802 LFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELP 861
Query: 938 KREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSA 997
K E L A + LES + + + D R ++ +++ + K+ R SA
Sbjct: 862 KLEKRL---RATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSA 918
Query: 998 QSQQQIR 1004
Q + IR
Sbjct: 919 QIAKPIR 925
Score = 62.8 bits (151), Expect = 2e-09
Identities = 83/395 (21%), Positives = 178/395 (45%), Gaps = 43/395 (10%)
Query: 848 QKRRLEAEMSKRQHRVKELELKHEQQQKIL-KIKT-----EEIAAFQRKRRSGSNGSVVS 901
++R+ E E++K ++ + + + QQ +++ K+KT EE+ A R+ + +
Sbjct: 417 ERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNR 476
Query: 902 LEQQ------------QKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEAL 949
L+ + Q +EE DQ+ ++V + + E L +EL+++ A LA +A
Sbjct: 477 LQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAE 536
Query: 950 MQ---EKTGLESKRLRSSQA-LNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRG 1005
+Q E T + KR A L +D+ + + + + + E +G + + + R
Sbjct: 537 LQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVA----RL 592
Query: 1006 EIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNE---A 1062
I ++ E +++K+ +++ + + E E+ L I +A I+ E
Sbjct: 593 YISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQN 652
Query: 1063 ITCRQRVLRASASLLSQCEMNLMA-------KLSYLSSSETRALLCKYFDKVVTLREEQH 1115
+ ++R L S LS+ + L A + +L+ +T + + ++ + E H
Sbjct: 653 VEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETH 712
Query: 1116 QQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRD-H 1174
Q+QI S L ++E + +L+ L+ ++ LE +R + EHE+ ++SR H
Sbjct: 713 QKQI--SSLRDEVEAKAKLITDLQDQNQKMMLEQER----LRVEHEKLKATDQEKSRKLH 766
Query: 1175 LGEGLADSRRQYEARIQALEKELGRYMWINQELKQ 1209
+ D R Q ++ LE+ + + + L++
Sbjct: 767 ELTVMQDRREQARQDLKGLEETVAKELQTLHNLRK 801
Score = 53.5 bits (127), Expect = 1e-06
Identities = 78/418 (18%), Positives = 171/418 (40%), Gaps = 50/418 (11%)
Query: 698 ASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRA 757
AS+ + + Q + ELA+N K + + + + + Q S + ++ E ++++
Sbjct: 483 ASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKE 542
Query: 758 ELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQS 817
+ +++ E+ L+D E +A + V+ + + T + +
Sbjct: 543 MTNHQKKRAAEMMASLLKDLAEIG--------IAVGNNDVK----QPEGTGMIDEEFTVA 590
Query: 818 EKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKIL 877
+ +++ V+ M ++ QL+ E ++ E E++ Q R+ + E K +
Sbjct: 591 RLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAK-------I 643
Query: 878 KIKTEEIAAFQRKRR------SGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALE- 930
K TE + ++K+R + +V L Q+K+ E +K +++ + ++A+E
Sbjct: 644 KSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQ 703
Query: 931 --ELGEELHK------REAILAKKEAL-----MQEKTGLESKRLRSSQALNEDIVRVSSR 977
+ E H+ R+ + AK + + +K LE +RLR + + SR
Sbjct: 704 QIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSR 763
Query: 978 LEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLR-------QEKDSLLKQRLEIDGKLRQ 1030
H + ++ Q RQ ++ + E+ +L Q+ + +K+ EID
Sbjct: 764 KLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTG 823
Query: 1031 GSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCR----QRVLRASASLLSQCEMNL 1084
GS ++ L E + + + N + C ++ LRA+A + E L
Sbjct: 824 GSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESAL 881
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 243 bits (620), Expect = 9e-64
Identities = 146/357 (40%), Positives = 220/357 (61%), Gaps = 27/357 (7%)
Query: 16 VRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRD-------RHFGFHVVLAEDAGQE 68
V+V +R RPL +E ++ + V+ G +T+ + + F F V ++ Q
Sbjct: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
Query: 69 AVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLLEDEQGIVPRAMAEA 127
VY +P++++ EG+N T+FAYGQTG+GKT+TM G ++ L +GI+P + A
Sbjct: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPEL----RGIIPNSFAHI 130
Query: 128 FKLID--ENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVD 185
F I E D LV VSYLE+Y EE RDLL R ++++E V + +
Sbjct: 131 FGHIAKAEGDTR-FLVRVSYLEIYNEEVRDLLGKDQTQR-LEVKERPDVGVYIKDLSAYV 188
Query: 186 VEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLE--QRGRAPSRLPRPAPGQL 243
V D++ ++ +G+ R GAT++N SSRSH +FT+T+E ++G + R
Sbjct: 189 VNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVR------ 242
Query: 244 LVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRD 303
+ K H VDLAGSER KTG+TG+RLKE+ +IN SL LGNVISAL D + +H+PYR+
Sbjct: 243 -MGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDG--KSTHVPYRN 299
Query: 304 SKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPE 360
SK+TR+L+DSLGGN+KT+M A + P+ ++DET++TL YA+RA+NI+N+A +N P+
Sbjct: 300 SKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPK 356
Score = 63.5 bits (153), Expect = 1e-09
Identities = 77/352 (21%), Positives = 153/352 (43%), Gaps = 73/352 (20%)
Query: 680 AVGGSKARVQARQVPPA------TASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKA 733
++GG+ + + PA T S R A + I+ A R+ E+
Sbjct: 309 SLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKA---RINED----------P 355
Query: 734 AQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAA 793
AL RQ + I EL+++ E+ E+S E + E + GE ++ RR
Sbjct: 356 KDALLRQFQKEIEELKKKLEEGE-EISGSDISGSEEDDDEEGEVGEDGEKRKKRRG---- 410
Query: 794 QSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLE 853
+KK + ++++ + A+ ++ + LE + + E E++ +
Sbjct: 411 --------KKKVSPDKMIEMQAKIDEERKALETKLDM--------------EEEERNKAR 448
Query: 854 AEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKK 913
AE+ KR+ K+L ++ Q +L E+++A ++K G ++ K EEQ+K
Sbjct: 449 AELEKRE---KDLLKAQQEHQSLL----EKLSALEKKVIVGG------VDLLAKAEEQEK 495
Query: 914 WLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVR 973
L++ ++ ++R+ E+L EL ++E QE+ +E K +L E+
Sbjct: 496 LLEESNMELEERRKRAEQLRRELEEKE----------QERLDIEEK----YTSLQEEAQG 541
Query: 974 VSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEID 1025
+ +L+ + L ++ + Q++I G ++++RQ L Q L ID
Sbjct: 542 KTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIID 593
Score = 45.8 bits (107), Expect = 3e-04
Identities = 58/258 (22%), Positives = 112/258 (43%), Gaps = 31/258 (12%)
Query: 958 SKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSL 1017
+K +++ +NED + L +KE+ E +L +G S I G + +++
Sbjct: 342 AKNIKNKARINED--PKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEED--DDEEGE 397
Query: 1018 LKQRLEIDGKLRQGSLLSPEEERTL-FQLDEAIEALDAAIEYKNEAITCRQRVLRASASL 1076
+ + E K R +SP++ + ++DE +AL+ ++ + E + L
Sbjct: 398 VGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKD 457
Query: 1077 LSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVY 1136
L + + + L LS+ E + ++ V L + +Q+ E M+LEE+++
Sbjct: 458 LLKAQQEHQSLLEKLSALEKKVIVGG-----VDLLAKAEEQEKLLEESNMELEERRKRAE 512
Query: 1137 WLEVAL---ERQRLEMDRQLTLQQKEHEQNMQLL----------------LQQSRDHLGE 1177
L L E++RL+++ + T Q+E + + L LQQ E
Sbjct: 513 QLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIE 572
Query: 1178 GLADSRRQY--EARIQAL 1193
GL ++ RQ E R+Q L
Sbjct: 573 GLLENIRQLSRELRLQML 590
Score = 42.7 bits (99), Expect = 0.002
Identities = 47/214 (21%), Positives = 100/214 (46%), Gaps = 29/214 (13%)
Query: 820 RLQELERNVQLMRQQQGQLQRRLREETEQ-KRRLEAEMSKRQHRVKELELKHEQQQKILK 878
R + ++ ++ + L R+ ++E E+ K++LE + ++ ++ +
Sbjct: 341 RAKNIKNKARINEDPKDALLRQFQKEIEELKKKLE-----EGEEISGSDISGSEEDDDEE 395
Query: 879 IKTEEIAAFQRKRRSGSNGSVVSL-EQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELH 937
+ E ++KRR S + E Q KI+E++K L+ +++ ++R EL
Sbjct: 396 GEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARA---ELE 452
Query: 938 KREAILAKKE----ALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLR 993
KRE L K + +L+++ + LE K + V + ++ E EK L E + +L
Sbjct: 453 KREKDLLKAQQEHQSLLEKLSALEKKVIVGG-------VDLLAKAEEQEKLLEESNMELE 505
Query: 994 QGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGK 1027
+ +++Q LR+E + ++RL+I+ K
Sbjct: 506 ERRKRAEQ--------LRRELEEKEQERLDIEEK 531
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 243 bits (619), Expect = 1e-63
Identities = 154/362 (42%), Positives = 209/362 (57%), Gaps = 31/362 (8%)
Query: 11 AEEAPVRVALRVRPLLPKELLHG---------HQSCLQVEP-----GLGRVTLGRDRHFG 56
+++ + VALRVRP+ EL G Q + ++P + R R++ +
Sbjct: 7 SKDQQLMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYL 66
Query: 57 FHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDE 116
F V A QE VYQA + L+E G+NATVFAYG TG GKTYTM + E
Sbjct: 67 FDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGT------DQE 120
Query: 117 QGIVPRAMAEAFKLIDE--NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERG 174
GI + + + F+ I+E ND+ + V +SYLE+Y E RDLL ++LRED +G
Sbjct: 121 PGIYVQTLNDLFRAIEETSNDM-EYEVSMSYLEIYNEMIRDLLNPSLGY--LELREDSKG 177
Query: 175 NVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSR 234
+ + G+ EV E++ LL GN R T N SSRSH V VT+ QR R +
Sbjct: 178 VIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNI 237
Query: 235 LPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQR 294
L G+L + +DLAGSER +T + G+R+KE IN SLLALGN I+AL D +
Sbjct: 238 LQEVRQGRLFM-----IDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSD-KG 291
Query: 295 RGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRAT 354
+I YRDSK+TR+LKDSLGGN++TVMIA +SP+SS F+E+ NTL YA RA+NI+ R
Sbjct: 292 SNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVK 351
Query: 355 VN 356
N
Sbjct: 352 QN 353
Score = 38.1 bits (87), Expect = 0.057
Identities = 85/358 (23%), Positives = 140/358 (39%), Gaps = 38/358 (10%)
Query: 701 WRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELS 760
+ +AQ I +L I+ + I E +TG+ QA RQ IR ++ E + +
Sbjct: 359 YHIAQYTSIIADLRGEIQRLKRKIDE--QTGRG-QARGRQDRGDIRHIQAEVQLHSGQGE 415
Query: 761 E-GQRQLRELEGKELQDAGE-RSRLQEFRRRVAAAQSQVQ-----VLKEKKQATERLVSL 813
+ G QLRE Q+ + R RL E R Q + K + + R +L
Sbjct: 416 KAGMGQLREQLASAFQEQMDVRRRLLELENRAMEVQIDTSRHLLTIAGWKHEKSRR--AL 473
Query: 814 SAQSEKRLQELERNVQLMRQQQGQLQRRLRE--ETEQKRRLEAEMSKRQHRVKELELKHE 871
+ E+R + ++ G Q + E E R A + Q ++++ +L E
Sbjct: 474 KWREEQRKECYAKDDSEKDSDTGDDQPDILEPPEVAAARESIAALVDEQKQLRKQKLALE 533
Query: 872 QQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEE 931
Q+ + L+ + + RR GS EQ++ + + + E+E Q AL
Sbjct: 534 QRCRELRARGRRLEE-TLPRRIGSE------EQREVLSLLCRVHELEVENTEMQSHALLR 586
Query: 932 LGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHL-EKELSE-KS 989
G H+ EA+ L Q ++ + Q +++ + V RLE L E L E +
Sbjct: 587 DGALRHRHEAV----RRLEQHRSLCDEIIQGQRQIIDDYNLAVPQRLEELYEVYLRELEE 642
Query: 990 GQLRQGSAQSQQQIRGEID-----------SLRQEKDSLLKQRLEIDGKLRQGSLLSP 1036
G L Q + Q R D SL + D + L D + Q S L P
Sbjct: 643 GSLEQATIMDQVASRALQDSSLPKITPAGTSLTPDSDLESVKTLSSDAQHLQNSALPP 700
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 239 bits (611), Expect = 1e-62
Identities = 179/533 (33%), Positives = 270/533 (50%), Gaps = 43/533 (8%)
Query: 13 EAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQ 72
E ++V R RPL E+L G + + + G V +G + + F V + QE VY
Sbjct: 7 ECSIKVLCRFRPLNQAEILRGDKF-IPIFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYH 64
Query: 73 ACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQ--GIVPRAMAEAFKL 130
AC +++ G+N T+FAYGQT SGKT+TM L D Q GI+PR + F
Sbjct: 65 ACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTM-----EGKLHDPQLMGIIPRIARDIFNH 119
Query: 131 I---DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 187
I DEN L+ + VSY E+Y ++ RDLL+V ++ + ED+ + G E V
Sbjct: 120 IYSMDEN--LEFHIKVSYFEIYLDKIRDLLDV--TKTNLSVHEDKNRVPFVKGCTERFVS 175
Query: 188 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSK 247
+E+L +++ G + RH T++N SSRSH++F + ++Q Q L K
Sbjct: 176 SPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETE--------QKLSGK 227
Query: 248 FHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKIT 307
+ VDLAGSE+V KTG+ G L E+ IN SL ALGNVISAL + + S++PYRDSK+T
Sbjct: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK--SYVPYRDSKMT 285
Query: 308 RILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN-------WRPE 360
RIL+DSLGGN +T M C SPSS + ET +TL + RA+ I+N A+VN W+ +
Sbjct: 286 RILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKK 345
Query: 361 AERPPEETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACTDAAY 420
E+ E+T + + +E G P + A LGAE D +
Sbjct: 346 YEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEA-ALGAELCEETPVNDNSS 404
Query: 421 SLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVE--DQAAQGAG 478
++R E R++ L + E + S IE + DQ
Sbjct: 405 IVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQL------IEKLKQQMLDQEELLVS 458
Query: 479 GRKEDEGAQQLLT-LQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEE 530
R ++E Q+ L+ LQ++ ++E ++ L ALE+ Y +S + E+ ++
Sbjct: 459 TRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQ 511
Score = 47.4 bits (111), Expect = 9e-05
Identities = 96/508 (18%), Positives = 214/508 (42%), Gaps = 68/508 (13%)
Query: 723 LIGELVRTGKAAQALNRQHS--QRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGER 780
+ G+ +T K ++N + + Q ++ E+E E+ +A+ + + +LE EL
Sbjct: 319 MFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQ----KETIAKLEA-ELSRWRNG 373
Query: 781 SRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQR 840
+ E R + L E+ + + + + Q+ E ++ + +Q
Sbjct: 374 ENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDD 433
Query: 841 RLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILK-IKTEEIAAFQRKRRSGSNGSV 899
+ ++++ +L+ +M ++ + +E+ Q+ L +++E AA +
Sbjct: 434 EINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVK-------- 485
Query: 900 VSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESK 959
E Q +EE DQ+ ++V ++ + + L +EL ++ A + LES+
Sbjct: 486 ---EVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLS----------LESE 532
Query: 960 RLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEID----------- 1008
R + R++ L L K+LSE S + G + +I G I+
Sbjct: 533 LQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYIS 592
Query: 1009 SLRQEKDSLLK-------------QRLEIDGK-LRQGSLLSPEEERTLFQLDEAIEALDA 1054
++ E S++K +++E+ G+ L LL + E + L E +++++
Sbjct: 593 KIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVEL 652
Query: 1055 AIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQ 1114
+ E+ L A L +Q ++ +A ++ + K + + E
Sbjct: 653 KKRHLEESYDSLSDEL---AKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREA 709
Query: 1115 HQQQIAFSELEMQLEEQQRLVYWL-----EVALERQRLEMDRQLTLQQKEHEQNMQLLLQ 1169
H +Q+A L ++ E+Q+ + L ++ LE ++L+ D + L+ +EHE++ +L
Sbjct: 710 HHRQLA--RLRDEINEKQKTIDELKDLNQKLQLELEKLQADYE-KLKSEEHEKSTKL--- 763
Query: 1170 QSRDHLGEGLADSRRQYEARIQALEKEL 1197
Q L E S++ + + + +EL
Sbjct: 764 QELTFLYERHEQSKQDLKGLEETVAREL 791
Score = 32.7 bits (73), Expect = 2.4
Identities = 46/217 (21%), Positives = 95/217 (43%), Gaps = 38/217 (17%)
Query: 711 RELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLREL- 769
R+LA R+++E I E +T + LN++ + +L+ + E++++E E +L+EL
Sbjct: 712 RQLA---RLRDE-INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELT 767
Query: 770 -------------EGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQ 816
+G E A E L R+ + +V K + E + +Q
Sbjct: 768 FLYERHEQSKQDLKGLEETVARELQTLHNLRK-LFVQDVTTRVKKSAEMEPEDSGGIHSQ 826
Query: 817 SEKRLQELERNVQLMRQQQGQL--------------QRRLREETEQKRRLEAEMSKRQHR 862
+K + LE N++ + + QL ++RLR E+ + LE + ++ +
Sbjct: 827 KQK-ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGAL--KEAK 883
Query: 863 VKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSV 899
++ K QQ++ +IK E ++ + G + +
Sbjct: 884 EGAMKDKRRYQQEVDRIK--EAVRYKSSGKRGHSAQI 918
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 232 bits (592), Expect = 2e-60
Identities = 136/308 (44%), Positives = 186/308 (60%), Gaps = 17/308 (5%)
Query: 51 RDRHFGFHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASV 109
+D F F V E + Q V++ +P+L +F G+N TV AYG TG+GKT+TM G A
Sbjct: 70 KDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSA-- 127
Query: 110 ASLLEDEQGIVPRAMAEAFKLIDE-NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQL 168
DE G++ M +K +DE + C VSYLEVY E+ RDLL S + +
Sbjct: 128 -----DEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL---VNSGPLAV 179
Query: 169 REDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQR 228
RED + VV+ G+ + +E+L LL+ GN R T +N SSRSH VF + L Q+
Sbjct: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
Query: 229 GRAPSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISA 288
+ S + ++K +DLAGSER +G+ G R E IN SLLALGNVI+A
Sbjct: 240 DKTAS-----INQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINA 294
Query: 289 LGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQN 348
L D +R+ HIPYR+SK+TR+LKDSLGGN +T+MIA VSPSS +D+T NTL YA+RA++
Sbjct: 295 LADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
Query: 349 IRNRATVN 356
I++ N
Sbjct: 355 IKSSLKSN 362
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 230 bits (587), Expect = 6e-60
Identities = 144/367 (39%), Positives = 212/367 (57%), Gaps = 32/367 (8%)
Query: 13 EAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQ 72
E ++V R RPL E+L G + + + G V +G+ + + F VL + QE VY
Sbjct: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFK-GDETVVIGQGKPYVFDRVLPPNTTQEQVYN 64
Query: 73 ACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQ--GIVPRAMAEAFKL 130
AC + +++ EG+N T+FAYGQT SGKT+TM L D Q GI+PR + F
Sbjct: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTM-----EGKLHDPQLMGIIPRIAHDIFDH 119
Query: 131 I---DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 187
I DEN L+ + VSY E+Y ++ RDLL+V + ++ + ED+ + G E V
Sbjct: 120 IYSMDEN--LEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNRVPYVKGCTERFVS 175
Query: 188 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSK 247
+EV+ +++ G A RH T++N SSRSH++F + ++Q + L K
Sbjct: 176 SPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK--------LSGK 227
Query: 248 FHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKIT 307
+ VDLAGSE+V KTG+ G L E+ IN SL ALGNVISAL + + +H+PYRDSK+T
Sbjct: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK--THVPYRDSKMT 285
Query: 308 RILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN-------WRPE 360
RIL+DSLGGN +T ++ C SPS + ET +TL + RA+ I+N +VN W+ +
Sbjct: 286 RILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKK 345
Query: 361 AERPPEE 367
E+ E+
Sbjct: 346 YEKEKEK 352
Score = 47.8 bits (112), Expect = 7e-05
Identities = 59/297 (19%), Positives = 132/297 (44%), Gaps = 38/297 (12%)
Query: 733 AAQALNRQHSQRIRELE---QEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRR 789
A Q L QH +I+ L Q EQ R +L E Q L E E ++L+
Sbjct: 628 ACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSE----------ELAKLR----- 672
Query: 790 VAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQK 849
AQ ++ + + + E L L +E+ + LE+ ++ R+ + RLR+E E+K
Sbjct: 673 ---AQEKMHEVSFQDKEKEHLTRLQ-DAEEMKKALEQQMESHREAHQKQLSRLRDEIEEK 728
Query: 850 RRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIE 909
+++ E +++L K + +Q+ L ++ ++R ++ +++++
Sbjct: 729 QKIIDE-------IRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAR 781
Query: 910 EQKKWLDQEMEKVLQQRRALEEL-GEELHKREAILAKKEALMQEKTG----LESKRLRSS 964
E K L++ + + LQ L +L ++L R KK + G + +++
Sbjct: 782 EDLKGLEETVSRELQTLHNLRKLFVQDLTTR----VKKSVELDNDDGGGSAAQKQKISFL 837
Query: 965 QALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQR 1021
+ E + +V +L +L + +L + + ++++ +L++ K++ ++ R
Sbjct: 838 ENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDR 894
Score = 41.6 bits (96), Expect = 0.005
Identities = 82/451 (18%), Positives = 183/451 (40%), Gaps = 70/451 (15%)
Query: 770 EGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQ 829
E KE D S ++ + Q Q+ ++ KQ L A + + ++++ +
Sbjct: 412 EEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELT 471
Query: 830 LMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQR 889
++ + + ++E + L ++ V++ +EQ L KT + QR
Sbjct: 472 RLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQR 531
Query: 890 KRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREA-ILAKKEA 948
+ L Q Q++ +K E+ +L + L E+G + + LA
Sbjct: 532 E-----------LSQLQELSNHQKKRATEILNLL--LKDLGEIGGIIGTNDVKTLADVNG 578
Query: 949 LMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEID 1008
+++E+ + + ++ + +V S +LE + + + K + A Q
Sbjct: 579 VIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQ-------- 630
Query: 1009 SLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQR 1068
LL + E K + + E++R QL+E+ ++L +
Sbjct: 631 --------LLISQHEAKIKSLTDYMQNMEQKRR--QLEESQDSLSEEL------------ 668
Query: 1069 VLRASASLLSQCEMNLMA----KLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSEL 1124
A L +Q +M+ ++ + +L+ + + K ++ + E HQ+Q+ S L
Sbjct: 669 -----AKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQL--SRL 721
Query: 1125 EMQLEEQQRLVYWL-----EVALERQRLEMD-RQLTLQQKEHEQNMQLLLQQSRDHLGEG 1178
++EE+Q+++ + ++ LE+++L D +L ++ +E E ++ LL
Sbjct: 722 RDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLL--------- 772
Query: 1179 LADSRRQYEARIQALEKELGRYMWINQELKQ 1209
L D R Q ++ LE+ + R + L++
Sbjct: 773 LNDKREQAREDLKGLEETVSRELQTLHNLRK 803
Score = 33.5 bits (75), Expect = 1.4
Identities = 44/196 (22%), Positives = 89/196 (45%), Gaps = 19/196 (9%)
Query: 709 KIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRE 768
+IR+L +++++E + K +++ L + EQ R +L + L E
Sbjct: 734 EIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDL----KGLEE 789
Query: 769 LEGKELQDAGERSRL--QEFRRRVAAAQSQVQVLKE-------KKQATERLVSLSAQSEK 819
+ELQ +L Q+ RV + V++ + +KQ L + Q K
Sbjct: 790 TVSRELQTLHNLRKLFVQDLTTRV---KKSVELDNDDGGGSAAQKQKISFLENNLEQLTK 846
Query: 820 RLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKI 879
++L R+ +R + +L++RLR E+ + LE+ + ++ + + + QQ++ +I
Sbjct: 847 VHKQLVRDNADLRCELPKLEKRLRATAERVKALESAL--KEAKENAMRDRKRYQQEVDRI 904
Query: 880 KTEEIAAFQRKRRSGS 895
K E + A RR+ S
Sbjct: 905 K-EAVRAKNMARRAHS 919
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 227 bits (579), Expect = 5e-59
Identities = 146/374 (39%), Positives = 218/374 (58%), Gaps = 35/374 (9%)
Query: 13 EAPVRVALRVRPLLPKEL---------LHGHQSCLQVEPGLGRVTLGRD-RHFGFHVVL- 61
+ V+VA+RVRP+ +EL + G+Q+ L P + + + F F
Sbjct: 3 DTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 62 -------AEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLL 113
+ AGQE V++ + +LE F+G+NA +FAYGQTGSGK+++M G A
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA------ 116
Query: 114 EDEQGIVPRAMAEAFKLI--DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLRED 171
++ G++PR FK I ++N+ V VSY+E+Y E+ RDLL+ + + +++RE
Sbjct: 117 -EQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREH 175
Query: 172 ERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRA 231
+ + G+ ++ V +++ SL+ GN +R AT++N SSRSH VF + + Q
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ---T 232
Query: 232 PSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGD 291
L G+ VSK VDLAGSERV KTG+ GERLKE IN SL LG VIS+L D
Sbjct: 233 LYDLQSGNSGEK-VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 292 P---QRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQN 348
+ + +PYRDS +T +LKD+LGGN++T MIA +SP++ +++ETL+TL YA RA+
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 349 IRNRATVNWRPEAE 362
I N A VN P A+
Sbjct: 352 IVNHAVVNEDPNAK 365
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 227 bits (579), Expect = 5e-59
Identities = 146/374 (39%), Positives = 218/374 (58%), Gaps = 35/374 (9%)
Query: 13 EAPVRVALRVRPLLPKEL---------LHGHQSCLQVEPGLGRVTLGRD-RHFGFHVVL- 61
+ V+VA+RVRP+ +EL + G+Q+ L P + + + F F
Sbjct: 3 DTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 62 -------AEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLL 113
+ AGQE V++ + +LE F+G+NA +FAYGQTGSGK+++M G A
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA------ 116
Query: 114 EDEQGIVPRAMAEAFKLI--DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLRED 171
++ G++PR FK I ++N+ V VSY+E+Y E+ RDLL+ + + +++RE
Sbjct: 117 -EQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREH 175
Query: 172 ERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRA 231
+ + G+ ++ V +++ SL+ GN +R AT++N SSRSH VF + + Q
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ---T 232
Query: 232 PSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGD 291
L G+ VSK VDLAGSERV KTG+ GERLKE IN SL LG VIS+L D
Sbjct: 233 LYDLQSGNSGEK-VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 292 P---QRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQN 348
+ + +PYRDS +T +LKD+LGGN++T MIA +SP++ +++ETL+TL YA RA+
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 349 IRNRATVNWRPEAE 362
I N A VN P A+
Sbjct: 352 IVNHAVVNEDPNAK 365
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 227 bits (579), Expect = 5e-59
Identities = 146/374 (39%), Positives = 218/374 (58%), Gaps = 35/374 (9%)
Query: 13 EAPVRVALRVRPLLPKEL---------LHGHQSCLQVEPGLGRVTLGRD-RHFGFHVVL- 61
+ V+VA+RVRP+ +EL + G+Q+ L P + + + F F
Sbjct: 3 DTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 62 -------AEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLL 113
+ AGQE V++ + +LE F+G+NA +FAYGQTGSGK+++M G A
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA------ 116
Query: 114 EDEQGIVPRAMAEAFKLI--DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLRED 171
++ G++PR FK I ++N+ V VSY+E+Y E+ RDLL+ + + +++RE
Sbjct: 117 -EQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREH 175
Query: 172 ERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRA 231
+ + G+ ++ V +++ SL+ GN +R AT++N SSRSH VF + + Q
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ---T 232
Query: 232 PSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGD 291
L G+ VSK VDLAGSERV KTG+ GERLKE IN SL LG VIS+L D
Sbjct: 233 LYDLQSGNSGEK-VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 292 P---QRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQN 348
+ + +PYRDS +T +LKD+LGGN++T MIA +SP++ +++ETL+TL YA RA+
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 349 IRNRATVNWRPEAE 362
I N A VN P A+
Sbjct: 352 IVNHAVVNEDPNAK 365
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 227 bits (579), Expect = 5e-59
Identities = 146/374 (39%), Positives = 218/374 (58%), Gaps = 35/374 (9%)
Query: 13 EAPVRVALRVRPLLPKEL---------LHGHQSCLQVEPGLGRVTLGRD-RHFGFHVVL- 61
+ V+VA+RVRP+ +EL + G+Q+ L P + + + F F
Sbjct: 3 DTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 62 -------AEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLL 113
+ AGQE V++ + +LE F+G+NA +FAYGQTGSGK+++M G A
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA------ 116
Query: 114 EDEQGIVPRAMAEAFKLI--DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLRED 171
++ G++PR FK I ++N+ V VSY+E+Y E+ RDLL+ + + +++RE
Sbjct: 117 -EQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREH 175
Query: 172 ERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRA 231
+ + G+ ++ V +++ SL+ GN +R AT++N SSRSH VF + + Q
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ---T 232
Query: 232 PSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGD 291
L G+ VSK VDLAGSERV KTG+ GERLKE IN SL LG VIS+L D
Sbjct: 233 LYDLQSGNSGEK-VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 292 P---QRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQN 348
+ + +PYRDS +T +LKD+LGGN++T MIA +SP++ +++ETL+TL YA RA+
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 349 IRNRATVNWRPEAE 362
I N A VN P A+
Sbjct: 352 IVNHAVVNEDPNAK 365
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 226 bits (577), Expect = 9e-59
Identities = 146/375 (38%), Positives = 216/375 (57%), Gaps = 38/375 (10%)
Query: 13 EAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTL-------------GRDRHFGF-H 58
++ V+VA+R+RP+ +E H C+ V+ +V L G+ + F + H
Sbjct: 3 DSKVKVAVRIRPMNRRET-DLHTKCV-VDVDANKVILNPVNTNLSKGDARGQPKVFAYDH 60
Query: 59 VVLAED-------AGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVAS 111
+ D AGQ+ V++ + +L+ F+G+NA +FAYGQTGSGK+YTM +
Sbjct: 61 CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTA--- 117
Query: 112 LLEDEQGIVPRAMAEAFKLI--DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLR 169
D+ G++PR + F+ +EN+ V VSY+E+Y E+ RDLL+ + + +++R
Sbjct: 118 ---DQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVR 174
Query: 170 EDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRG 229
E + G+ ++ V ++ SL+ GN +R AT++N SSRSH VF +TL
Sbjct: 175 EHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTH-- 232
Query: 230 RAPSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISAL 289
+ G+ V K VDLAGSER KTG+ G+RLKE IN SL LG VISAL
Sbjct: 233 -TLYDVKSGTSGEK-VGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISAL 290
Query: 290 GDP---QRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRA 346
D + + +PYRDS +T +LKDSLGGN+KT M+A VSP++ ++DETL+TL YA RA
Sbjct: 291 ADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRA 350
Query: 347 QNIRNRATVNWRPEA 361
++I N A VN P A
Sbjct: 351 KHIVNHAVVNEDPNA 365
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 223 bits (568), Expect = 1e-57
Identities = 142/363 (39%), Positives = 200/363 (55%), Gaps = 38/363 (10%)
Query: 12 EEAPVRVALRVRPLLPKELLHGHQSCLQVE----------------PGL-------GRVT 48
E++ ++V +RVRP P+EL + +QV PGL G
Sbjct: 4 EDSTLQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFNPEEPDGGFPGLKWGGTHDGPKK 63
Query: 49 LGRDRHFGFHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEAS 108
G+D F F V E A Q+ V+Q +L++F +G+N +VFAYG TG+GKT+TM
Sbjct: 64 KGKDLTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGR- 122
Query: 109 VASLLEDEQGIVPRAMAEAFKLIDENDLLDCL-VHVSYLEVYKEEFRDLLEVGTASRDIQ 167
E + GI+ E ++ ++ V +SY EVY E+ DLLE +
Sbjct: 123 -----EGDPGIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLLE---PKGPLA 174
Query: 168 LREDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQ 227
+RED VV+ G+ +++L +L GN R T N SSRSH +F + ++Q
Sbjct: 175 IREDPDKGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQ 234
Query: 228 RGRAPSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVIS 287
+ R P + V+K +DLAGSER T + GERL+E IN SLLAL NV++
Sbjct: 235 QDRVPGLTQA-----VQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLN 289
Query: 288 ALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQ 347
AL D + R +H+PYRDSK+TR+LKDSLGGN +TVMIA +SPSS +++T NTL YA RA+
Sbjct: 290 ALADAKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAK 349
Query: 348 NIR 350
IR
Sbjct: 350 EIR 352
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 223 bits (567), Expect = 1e-57
Identities = 140/347 (40%), Positives = 195/347 (56%), Gaps = 13/347 (3%)
Query: 11 AEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRV-TLGRDRHFGFHVVLAEDAGQEA 69
AEE V V +RVRPL +E G + + + + + + F F V + +
Sbjct: 2 AEEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKN 61
Query: 70 VYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEAFK 129
VY+ P++++ +G+N T+FAYGQT SGKTYTM + ED G++PRA+ + F+
Sbjct: 62 VYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGS------EDHLGVIPRAIHDIFQ 115
Query: 130 LIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGL 189
I + + L+ VSY+E+Y E DLL + + +RED NV + + E V
Sbjct: 116 KIKKFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTS 175
Query: 190 DEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSKFH 249
+ L + G +RH G T +N SSRSHT+F + LE R + P G + VS +
Sbjct: 176 EMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGE---PSNCEGSVKVSHLN 232
Query: 250 FVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRI 309
VDLAGSER +TG+ G RLKE IN SL LG VI L D Q G I YRDSK+TRI
Sbjct: 233 LVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQ-VGGFINYRDSKLTRI 291
Query: 310 LKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN 356
L++SLGGNAKT +I ++P S FDETL L +AS A+ ++N VN
Sbjct: 292 LQNSLGGNAKTRIICTITPVS--FDETLTALQFASTAKYMKNTPYVN 336
Score = 92.4 bits (228), Expect = 3e-18
Identities = 117/524 (22%), Positives = 238/524 (45%), Gaps = 76/524 (14%)
Query: 705 QAQQKIREL-AINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
Q ++ I+E+ A ++ +EEL K A ++ + I EL + E+S Q
Sbjct: 1460 QLKENIKEIVAKHLETEEEL--------KVAHCCLKEQEETINELRVNLSEKETEISTIQ 1511
Query: 764 RQLRELEGK---ELQDAGERSRLQEFR-RRVAAAQSQVQVLKEKKQ-------ATERLVS 812
+QL + K ++Q+ E+ ++F ++++ Q +V LK+ K+ A + + S
Sbjct: 1512 KQLEAINDKLQNKIQEIYEKE--EQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIES 1569
Query: 813 LSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQ 872
+ RLQE + +Q+M ++E+ E KR EA +R +LK
Sbjct: 1570 KMLELTNRLQESQEEIQIM----------IKEKEEMKRVQEALQIERD------QLKENT 1613
Query: 873 QQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKV-LQQRRALEE 931
++ + K+K + +Q + + N + + + + ++EQ + +E + + R +
Sbjct: 1614 KEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQI 1673
Query: 932 LGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLE------KEL 985
L E L + ++ +++ L + L+ +R + + L E I R + E L+ KE
Sbjct: 1674 LHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEH 1733
Query: 986 SEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQL 1045
E +LR ++ +I L D+L Q L+I +LR + E++
Sbjct: 1734 QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQ------ 1787
Query: 1046 DEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFD 1105
E I+ L + K + ++ Q+ L S + L + K+ L ++E
Sbjct: 1788 -ETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQE-------KIQELKANE---------H 1830
Query: 1106 KVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQ 1165
+++TL+++ ++ Q SE+E QL++Q + + +L +LE++ L L QK HE +
Sbjct: 1831 QLITLKKDVNETQKKVSEME-QLKKQIK-----DQSLTLSKLEIE-NLNLAQKLHENLEE 1883
Query: 1166 L-LLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELK 1208
+ + + RD+L + + + ++L++ R + I QELK
Sbjct: 1884 MKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELK 1927
Score = 80.1 bits (196), Expect = 1e-14
Identities = 118/540 (21%), Positives = 245/540 (45%), Gaps = 67/540 (12%)
Query: 697 TASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVR 756
T ++ + Q+K RE+ + E+L +L Q + R+ + +L+Q E+V+
Sbjct: 866 TELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVK 925
Query: 757 AELSEGQRQLREL-EGKELQDAGERSRLQEFRRRVAAAQSQVQ-VLKEKKQATERLVSLS 814
L++ + L++L E +++ +S + + Q Q++ L+ KQ E + +L
Sbjct: 926 T-LTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLK 984
Query: 815 AQSEKRLQELERNVQLMRQQQGQLQRRLREE---TEQKRRLEAEMSKR-QHRVKELELKH 870
+ K +E+ RN+ M + G+ + +++ ++K+ LEA+ ++ VK+ E+
Sbjct: 985 S---KISEEVSRNLH-MEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEI-I 1039
Query: 871 EQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALE 930
EQQ+KI + E+ Q SV++ ++Q K + L + +E ++ + L
Sbjct: 1040 EQQRKIFSLIQEKNELQQMLE------SVIAEKEQLKTD-----LKENIEMTIENQEELR 1088
Query: 931 ELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSG 990
LG+EL K++ I+A+++ +K G ++ R RL +E++L EKS
Sbjct: 1089 LLGDELKKQQEIVAQEKNHAIKKEG--------------ELSRTCDRLAEVEEKLKEKSQ 1134
Query: 991 QLRQGSAQ---------SQQQIRGEIDSLRQE---KDSLLK----QRLEIDGKLRQGSLL 1034
QL++ Q Q+ EI++L+ E K+ L+ +RLE+ KL +
Sbjct: 1135 QLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNE---- 1190
Query: 1035 SPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSS 1094
+ EE +++ + + ++ L + E + + + R + A+ L E +A +
Sbjct: 1191 NYEEVKSITKERKVLKELQKSFETERDHL--RGYIREIEATGLQTKEELKIAHIHLKEHQ 1248
Query: 1095 ET----RALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMD 1150
ET R + + +++ ++ + E+ + EEQ+ L EV+ ++ +
Sbjct: 1249 ETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNEL 1308
Query: 1151 RQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQK 1210
LT Q + ++ R L E +S+ + I++L KE I + L+ K
Sbjct: 1309 ELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEE----IKSLTKERDNLKTIKEALEVK 1364
Score = 72.0 bits (175), Expect = 4e-12
Identities = 109/530 (20%), Positives = 231/530 (43%), Gaps = 78/530 (14%)
Query: 734 AQALNRQHSQRI-----RELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRR 788
AQ L Q RI +E ++ +++R +SE +L ++ K+L+++ ++LQE +
Sbjct: 1767 AQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQ-KDLENSN--AKLQEKIQ 1823
Query: 789 RVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQ 848
+ A + Q+ LK+ T++ VS Q +K++++ + + + L ++L E E+
Sbjct: 1824 ELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEE 1883
Query: 849 KRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKI 908
+ + E + + L+L+ +Q ++ L+ Q++ ++ S
Sbjct: 1884 MKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLS---------- 1933
Query: 909 EEQKKWLDQEMEKVLQQ-------RRALEELGEELHKREAILAKKEALM---QEKTGLES 958
+E K+ +D+ EK+ ++ ++ L++ +EL K+ L KKE + +E +
Sbjct: 1934 KEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSH 1993
Query: 959 KRLRSSQALN-----EDIVRVSSRLEH--LEKELSEKSGQLRQGSAQSQQQIRGEIDSLR 1011
K++ + L +++ S R+++ L K+L E ++R A+ + ++R +SL+
Sbjct: 1994 KKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRI-VAKERDELRRIKESLK 2052
Query: 1012 QEKDSLLKQRLEIDGKLRQGSLLSPEEE----------RTLFQLDEAIEALDAAIEYKNE 1061
E+D + E+ + RQ + PE+ +L + I+ L ++
Sbjct: 2053 MERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDD 2112
Query: 1062 AITCRQRV---LRASASLLSQCEMNLMAKLS--YLSSSETRALL---------------- 1100
C R+ L + M + A LS YL + L
Sbjct: 2113 HYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKK 2172
Query: 1101 CKYFDKVVT-LREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQL---TLQ 1156
KY VT ++EEQH+ F + E+Q+ E+ ++ Q L+ D + L+
Sbjct: 2173 LKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQK-----ELLIKIQHLQQDCDVPSRELR 2227
Query: 1157 QKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYM--WIN 1204
+ QNM L +++ E S + ++ + KE+ +++ W+N
Sbjct: 2228 DLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLN 2277
Score = 62.4 bits (150), Expect = 3e-09
Identities = 97/533 (18%), Positives = 227/533 (42%), Gaps = 86/533 (16%)
Query: 707 QQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQL 766
Q+++R +++ +E I L + N + E + E +Q + + Q
Sbjct: 963 QEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQ--- 1019
Query: 767 RELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELER 826
+LE K Q + E + + +++EK + + L S+ A+ E+ +L+
Sbjct: 1020 -DLEAKNTQTLTADVKDNEI---IEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKE 1075
Query: 827 NVQLMRQQQGQLQRRLREETEQKRRL-----------EAEMSKRQHRVKELELKHEQQQK 875
N+++ + Q +L R L +E ++++ + E E+S+ R+ E+E K +++ +
Sbjct: 1076 NIEMTIENQEEL-RLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQ 1134
Query: 876 ILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVL-------QQRRA 928
L+ K +++ Q + E Q+KI E + ++ K L ++
Sbjct: 1135 QLQEKQQQLLNVQEEMS----------EMQKKINEIENLKNELKNKELTLEHMETERLEL 1184
Query: 929 LEELGEELHKREAILAKKEALMQEKTGLESKR--------------LRSSQALNEDIVRV 974
++L E + ++I +++ L + + E++R L++ + L + +
Sbjct: 1185 AQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHL 1244
Query: 975 SSR---LEHLEKELSEKSGQL--RQGSAQSQQQIRGEIDSLRQEKDSL--LKQRLEIDGK 1027
++ L + +SEK+ Q+ Q +S +++ EI L +E++ L +K+ E
Sbjct: 1245 KEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQET 1304
Query: 1028 LRQGSLLSPE----EERTLFQLD-----------EAIEALDAAIEYKNEAITCRQRVLRA 1072
+ + LL+ + + TL +++ E+ E + + + ++ T ++ L
Sbjct: 1305 MNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKE-ALEV 1363
Query: 1073 SASLLSQCEMNLMAKLSYLSSSETRALLCKYFD----KVVTLREEQHQQQIAFSELEMQL 1128
L + +AK+ S + ++L K D K+V+ E+ + A +E+++
Sbjct: 1364 KHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEM 1423
Query: 1129 EEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLAD 1181
L ++ Q + + ++K+ Q +Q +LQ D L E + +
Sbjct: 1424 ---------LGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKE 1467
Score = 60.5 bits (145), Expect = 1e-08
Identities = 104/543 (19%), Positives = 234/543 (43%), Gaps = 62/543 (11%)
Query: 705 QAQQKIRELAINIRMKEELI----GELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELS 760
+ ++K++ELA + E I +L K L ++ E+ + + ++
Sbjct: 650 ELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVP 709
Query: 761 EGQRQLRELEGK--ELQ-----DAGERSRLQE---FRRRVAAAQSQVQVL-KEKKQATER 809
+ ELEGK +LQ + E L+E + + S+V+ L KE + +E
Sbjct: 710 KDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEE 769
Query: 810 LVSLSAQSEKRLQEL---ERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKEL 866
L ++++ +K E+ E VQ + ++ G+ + L + + E K L
Sbjct: 770 LHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQN----FKTL 825
Query: 867 ELKHEQQQKIL-----KIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEK 921
+ EQ+ K++ ++ E + + ++ S+ + E K +E L ++ +
Sbjct: 826 HMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQE----LQEKTRE 881
Query: 922 VLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHL 981
V ++ +E+L E+L R++ L E +EKT L +++L+ + + + + L+ L
Sbjct: 882 VQERLNEMEQLKEQLENRDSTLQTVE---REKT-LITEKLQQTLEEVKTLTQEKDDLKQL 937
Query: 982 EKELSEKSGQLRQG-------SAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLL 1034
++ L + QL+ + +Q+Q+R ++SL+Q ++++ + +I ++ + +
Sbjct: 938 QESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHM 997
Query: 1035 SPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSS 1094
EE T DE + + I+ K + + L A E +
Sbjct: 998 ---EENTGETKDEFQQKM-VGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKN 1053
Query: 1095 ETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLT 1154
E + +L + V +EQ + + +EM +E Q+ E+ L L+ +++
Sbjct: 1054 ELQQML-----ESVIAEKEQLKTDLK-ENIEMTIENQE------ELRLLGDELKKQQEIV 1101
Query: 1155 LQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGV 1214
Q+K H + L ++ D LA+ + + + Q L+++ + + + +E+ + +
Sbjct: 1102 AQEKNHAIKKEGELSRTCDR----LAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI 1157
Query: 1215 NAV 1217
N +
Sbjct: 1158 NEI 1160
Score = 43.9 bits (102), Expect = 0.001
Identities = 83/416 (19%), Positives = 168/416 (40%), Gaps = 38/416 (9%)
Query: 735 QALNRQHSQRIRELEQEAE------QVRAELSEGQRQLRELEGKELQDAGERSRLQEFRR 788
+++N+ I E+E++ E ++ + R+LR+L+ + D L++F
Sbjct: 2189 ESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSE 2248
Query: 789 RV--AAAQSQVQVLKEKKQATERL---VSLSAQSEKRLQELERNVQLMRQQQGQLQRRL- 842
+ QVL +K+ T+ L ++ EK +++ + Q R+
Sbjct: 2249 SEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRII 2308
Query: 843 ---REETEQKRRLEAEMSKRQHRVKELELKHEQQQK---ILKIKTEEIAAFQRKRRSGSN 896
E TE + R + + +K L+ K+E+ K LK A + N
Sbjct: 2309 AIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKN 2368
Query: 897 GSVVSLEQQ---QKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEK 953
V S Q +KI E + L + E + + + ++ +EL I+AK +A + E
Sbjct: 2369 PHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHES 2428
Query: 954 TGLESKRLRSSQALNEDIV----RVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDS 1009
K + Q L + + +E L+ +L + + + + + +++I +
Sbjct: 2429 NKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKAT 2488
Query: 1010 LRQEKD--SLLKQRLEIDGKLRQGSLLS------PEEERTLFQLDEAIEALDAAIEYKNE 1061
+ +K+ LL++ L + + S++S P + I A+ K+E
Sbjct: 2489 VEYQKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSE 2548
Query: 1062 AITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQ 1117
I R+ + + L Q E + K LS+++ + K + K TL+ E H+Q
Sbjct: 2549 HI----RLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTW-KERTLKREAHKQ 2599
Score = 40.4 bits (93), Expect = 0.012
Identities = 96/492 (19%), Positives = 204/492 (41%), Gaps = 60/492 (12%)
Query: 735 QALNRQHSQRI----RELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRV 790
+AL +++ + I ++LE+ + + RA+ E + + LE K+L + +++ R +
Sbjct: 342 EALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRML 401
Query: 791 AAAQS----QVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREET 846
+ S Q K K++ T L ++ + + + +L L E
Sbjct: 402 VTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREI 461
Query: 847 EQKRRLEAEM-SKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQ 905
++ E+++ S + E+E + + E I + R+ + V+ EQ
Sbjct: 462 DESVCSESDVFSNTLDTLSEIEWNPATK----LLNQENIESELNSLRADYDNLVLDYEQL 517
Query: 906 QKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQ 965
+ +E EME L+++ L+E E +R+ ++ L+ E + L++ ++ ++
Sbjct: 518 RTEKE-------EMELKLKEKNDLDEF--EALERKTKKDQEMQLIHEISNLKN-LVKHAE 567
Query: 966 ALNEDIV-RVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGE-------IDSLRQEKDSL 1017
N+D+ +SS++E L ++ + +Q + I+ + I+ +Q K +L
Sbjct: 568 VYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTL 627
Query: 1018 L-KQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASL 1076
+ + +D K R+ + L E +L E ++ L + I Q L A +
Sbjct: 628 FDAETVALDAK-RESAFLRSEN----LELKEKMKELATTYKQMENDIQLYQSQLEAKKKM 682
Query: 1077 LSQCEMNLMAKL-------SYLSSSETRALLC--KYFDKVVTLREEQHQQQIAFSELEMQ 1127
E L + S + + LLC + K+ L++E +++ E E
Sbjct: 683 QVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKE---VEENEAL 739
Query: 1128 LEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYE 1187
EE L + E +RL + +Q K E + ++ +D L + E
Sbjct: 740 REEVILLSELKSLPSEVERLRKE----IQDKSEELH---IITSEKDKLFSEVVHK----E 788
Query: 1188 ARIQALEKELGR 1199
+R+Q L +E+G+
Sbjct: 789 SRVQGLLEEIGK 800
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 221 bits (564), Expect = 3e-57
Identities = 148/376 (39%), Positives = 211/376 (56%), Gaps = 45/376 (11%)
Query: 14 APVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVT-----------LGRDR------HFG 56
A V+VA+RVRP+ +E + +Q+E +T GR+R F
Sbjct: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
Query: 57 FHVVLAED---AGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLL 113
F+ + QE V++ ++++ FEG+NA VFAYGQTGSGK+YTM S
Sbjct: 62 FYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNS----- 116
Query: 114 EDEQGIVPRAMAEAFKLIDEN---DLLDCLVHVSYLEVYKEEFRDLLEVGTASR-DIQLR 169
+ G++PR F I+E D VSYLE+Y E RDLL ++ ++++R
Sbjct: 117 -GDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVR 175
Query: 170 EDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRG 229
E + + + + V+ +V L++ GN R T AT +N +SSRSH +FT+ Q
Sbjct: 176 EHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQ-A 234
Query: 230 RAPSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISAL 289
+ S +P VSK H VDLAGSER TG+TG RLKE IN SL+ LGNVISAL
Sbjct: 235 KFDSEMPCET-----VSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISAL 289
Query: 290 GD---------PQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTL 340
D +++ +PYRDS +T +LKDSLGGN+KT+MIA +SP+ ++ ETL+TL
Sbjct: 290 ADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTL 349
Query: 341 NYASRAQNIRNRATVN 356
YA+RA+NI N+ T+N
Sbjct: 350 RYANRAKNIINKPTIN 365
Score = 90.1 bits (222), Expect = 1e-17
Identities = 126/550 (22%), Positives = 234/550 (42%), Gaps = 46/550 (8%)
Query: 707 QQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQL 766
+++ RE + K +LI E+ K+ +A + Q + +E E V+ ++ + + L
Sbjct: 599 ERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESL 658
Query: 767 RE----LEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQ 822
+ +E K E+ + +E R R + Q L++K+Q E + + + + RL+
Sbjct: 659 KRRSFHIENKLKDLLAEKEKFEEERLR----EQQEIELQKKRQEEETFLRVQEELQ-RLK 713
Query: 823 ELERNVQLMRQQQGQ-LQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKT 881
EL N + + Q Q L + +E+ EQ +LE E + + + KE + ++ L+ K
Sbjct: 714 ELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQ 773
Query: 882 EEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRAL---EELGEELHK 938
E I +R G V Q +EE+K+ L+ E +L+ + A +E GEEL K
Sbjct: 774 EMIQLLRR-------GEV------QWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEK 820
Query: 939 REAILAK-KEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSA 997
+ + K + + LE ++ L +++ LE L+ E ++S L
Sbjct: 821 AQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLL----- 875
Query: 998 QSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDE-AIEALDAAI 1056
+ + ++ + Q+ + + + K RQ L TL + + A E LD
Sbjct: 876 EKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGP 935
Query: 1057 EYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQ 1116
+ + ++ + L+Q + N ++ E A + + +KV + +
Sbjct: 936 LSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKV-----RKKE 990
Query: 1117 QQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLG 1176
++I S + Q E +R + LER+ + R TL + EQ +L S
Sbjct: 991 KEILESREKQQREALERAL----ARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQ 1046
Query: 1177 EGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAVGHSRGGEKRSLCSEGRQAP 1236
GL S EA +ALEK+ R + Q+LKQK+ V+ V G + P
Sbjct: 1047 SGLQAS---LEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASS-SLP 1102
Query: 1237 GNEDELHLAP 1246
+ ++ HL P
Sbjct: 1103 VSAEKSHLVP 1112
Score = 60.8 bits (146), Expect = 8e-09
Identities = 134/571 (23%), Positives = 244/571 (42%), Gaps = 108/571 (18%)
Query: 800 LKEKKQATERLVSLSAQSEKRLQELERNVQ-LMRQQQG-QLQRRLREETEQ---KRRLEA 854
L+EK+++ L+S + S L + N+ +M G + +R+ REE E+ KR+L
Sbjct: 560 LREKRKSG--LLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIE 617
Query: 855 EMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGS---------NGSVVSLEQQ 905
EM ++Q + + EL+ QQ+ + K EI Q +++ S N L ++
Sbjct: 618 EMEEKQ-KSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEK 676
Query: 906 QKIEEQKKWLDQEMEKVLQQRRALEE----LGEELHKREAI----LAKKEALMQE----- 952
+K EE++ QE+E LQ++R EE + EEL + + + A+K + QE
Sbjct: 677 EKFEEERLREQQEIE--LQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQ 734
Query: 953 --------KTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQ---LRQGSAQSQQ 1001
K LE KRL + E ++ V+ HLE++L EK LR+G Q +
Sbjct: 735 KEKDEQYAKLELEKKRLEEQE--KEQVMLVA----HLEEQLREKQEMIQLLRRGEVQWVE 788
Query: 1002 QIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTL-FQLDEAIEALDAAIEYKN 1060
+ + +++ +R +SLL+ + G G L + R F+ + ++ ++ +
Sbjct: 789 EEKRDLEGIR---ESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQ 845
Query: 1061 EAITCRQRVLRASASL-LSQCEMNLMAKL--SYLSSSETRALLCKYFDKVVTLR-----E 1112
+ ++ V L +CE + ++L + S + + F+K+ + +
Sbjct: 846 QKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYK 905
Query: 1113 EQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQ--- 1169
E+ Q + + L LEE+QR E+ L+R L +D L +KE E+ + L Q
Sbjct: 906 ERQLQYLLQNHLPTLLEEKQRA---FEI-LDRGPLSLDNTLYQVEKEMEEKEEQLAQYQA 961
Query: 1170 -----QSRDHLGEGLADSRRQYE-------------------------ARIQALEKELGR 1199
Q E A+ RQ E AR++ L R
Sbjct: 962 NANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQR 1021
Query: 1200 YMWINQEL---KQKLGGVNAVGHSRGGEKRSLCSEGRQAPGNEDELHLAPELLWLSPL-- 1254
+ + E+ +QKL +N+ + G + SL E Q +D+ L E+ L
Sbjct: 1022 HSTLGMEIEEQRQKLASLNSGSREQSGLQASL--EAEQEALEKDQERLEYEIQQLKQKIY 1079
Query: 1255 -TEGAPRTREETRD--LVHAPLPLTWKRSSL 1282
+G + T + + + LP++ ++S L
Sbjct: 1080 EVDGVQKDHHGTLEGKVASSSLPVSAEKSHL 1110
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 220 bits (560), Expect = 8e-57
Identities = 142/359 (39%), Positives = 209/359 (58%), Gaps = 29/359 (8%)
Query: 16 VRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTL--------GRDRHFGFHVVLAEDAGQ 67
++V +R RP E S ++ +P V++ + + F +V Q
Sbjct: 19 IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQ 78
Query: 68 EAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLLEDEQ----GIVPR 122
VY++ V P+L+ G+N T+FAYGQTG+GKT+TM GE S E+ GI+PR
Sbjct: 79 IDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPR 138
Query: 123 AMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGT-ASRDIQLREDERGN--VVLC 179
+ + F+ + +N + V VS LE+Y EE DLL + S +Q+ +D R V++
Sbjct: 139 TLHQIFEKLTDNGT-EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIK 197
Query: 180 GVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPA 239
G++E+ V DEV +LE G A R T AT +N SSRSH+VF+VT+ +
Sbjct: 198 GLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETT-------I 250
Query: 240 PGQLLVS--KFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGS 297
G+ LV K + VDLAGSE + ++G+ +R +E+ IN SLL LG VI+AL + R
Sbjct: 251 DGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE---RTP 307
Query: 298 HIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN 356
H+PYR+SK+TRIL+DSLGG +T +IA +SP+S + +ETL+TL YA RA+NI N+ VN
Sbjct: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVN 366
Score = 41.2 bits (95), Expect = 0.007
Identities = 78/377 (20%), Positives = 153/377 (40%), Gaps = 40/377 (10%)
Query: 697 TASEWRLAQAQQKIRELAINIRMKEELIG--ELVRTGKA-----AQALNRQHSQRIRELE 749
TA+ A + + ++ I MKE I ELV+ GK A + N S + +
Sbjct: 223 TAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRA 282
Query: 750 QEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATER 809
+EA + L R + L + S+L + +++ ++ A+
Sbjct: 283 REAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLN 342
Query: 810 L------VSLSAQSEKRLQELERNVQL-----MRQQQGQLQRRLREETEQKRRLEAEMSK 858
L + + +++ L + E N +L +++ +++R R+ + + +S+
Sbjct: 343 LEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISE 402
Query: 859 RQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQE 918
RV +L +++Q + I E+I A + + V L K E LDQ
Sbjct: 403 ENFRVMSGKLTVQEEQIVELI--EKIGAVEEELNR-----VTELFMDNKNE-----LDQC 450
Query: 919 MEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRL 978
+ + + LE + L + + L K+E + E K ++ L + + +
Sbjct: 451 KSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDV 510
Query: 979 EHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEE 1038
L +L K + Q +A++Q ++SL + L+K DG +Q ++L E
Sbjct: 511 SGLHSKLDRKKA-VDQHNAEAQDIFGKNLNSLFNNMEELIK-----DGSSKQKAML--EV 562
Query: 1039 ERTLF--QLDEAIEALD 1053
+TLF L ++ ALD
Sbjct: 563 HKTLFGNLLSSSVSALD 579
Score = 31.6 bits (70), Expect = 5.4
Identities = 40/194 (20%), Positives = 79/194 (40%), Gaps = 14/194 (7%)
Query: 901 SLEQQQKIEEQKKWLDQEMEKVLQQRRALEE-----LGEELHK----REAILAKKEALMQ 951
SL KIE+QKK LD + + L+E L E + E + K+ Q
Sbjct: 661 SLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQ 720
Query: 952 EKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLR 1011
E L + AL E + L +++ + +KS + Q+ + D
Sbjct: 721 ELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS 780
Query: 1012 QEKDSLLKQRLE-IDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNE----AITCR 1066
QE + ++ + ++ ++ L+ E+ + ++ E+L+ Y +E ++ R
Sbjct: 781 QELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNER 840
Query: 1067 QRVLRASASLLSQC 1080
++ L ++SQC
Sbjct: 841 EQELHNLLEVVSQC 854
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 212 bits (539), Expect = 2e-54
Identities = 137/371 (36%), Positives = 205/371 (55%), Gaps = 35/371 (9%)
Query: 14 APVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRD-----RHFGFHV-----VLAE 63
A V+VA+RVRP +E+ + +Q+ + + + F F E
Sbjct: 4 ASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPE 63
Query: 64 D---AGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIV 120
D A Q+ VY+ + +L+ FEG+N +FAYGQTG+GK+YTM + +D+QGI+
Sbjct: 64 DINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTM----MGKQEKDQQGII 119
Query: 121 PRAMAEAFKLIDE--NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVL 178
P+ + F I++ ND + V VSY+E+Y E RDLL ++++RE +
Sbjct: 120 PQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKG-NLRVREHPLLGPYV 178
Query: 179 CGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQ-RGRAPSRLPR 237
+ ++ V +++ L++ GN AR AT++N SSRSH VF + Q R A + +
Sbjct: 179 EDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITT 238
Query: 238 PAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGD------ 291
VSK VDLAGSER TG+ G RLKE IN SL LG VISAL +
Sbjct: 239 EK-----VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPN 293
Query: 292 ---PQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQN 348
+++ IPYRDS +T +L+++LGGN++T M+A +SP+ ++DETL+TL YA RA+
Sbjct: 294 KNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQ 353
Query: 349 IRNRATVNWRP 359
IR A +N P
Sbjct: 354 IRCNAVINEDP 364
Score = 31.6 bits (70), Expect = 5.4
Identities = 67/302 (22%), Positives = 114/302 (37%), Gaps = 40/302 (13%)
Query: 930 EELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKS 989
EE E L + E I+A+ +EK LR ++A+ + + L + + E
Sbjct: 431 EEAIERLKETEKIIAELNETWEEK-------LRRTEAIR---MEREALLAEMGVAMREDG 480
Query: 990 GQLRQGSAQSQQQIRG-EIDSLRQE------KDSLLKQRLEIDGKLRQGSLLSP---EEE 1039
G L S + + D L E KD + + E DG+ RQ +LS +EE
Sbjct: 481 GTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGRE-DGERRQDIVLSGHFIKEE 539
Query: 1040 RTLFQLDE--------AIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYL 1091
+F+ D +E + A Y N +LR+ ++
Sbjct: 540 HCVFRSDSRGGSEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNHPEQ 599
Query: 1092 SSSETRALLC-----KYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQR 1146
+ E C + D RE +Q I +M+ E +QRL LE R+R
Sbjct: 600 ARQERERTPCAETPAEPVDWAFAQRELLEKQGI-----DMKQEMEQRLQE-LEDQYRRER 653
Query: 1147 LEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQE 1206
E L Q+ ++E ++ L +Q + + + E +Q E+E +W ++
Sbjct: 654 EEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRK 713
Query: 1207 LK 1208
K
Sbjct: 714 WK 715
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 207 bits (527), Expect = 5e-53
Identities = 141/367 (38%), Positives = 195/367 (53%), Gaps = 35/367 (9%)
Query: 12 EEAPVRVALRVRPLLP---------------KELLHGHQSCLQVEPGLGRVTLGRDRHFG 56
E + V VA+RVRP KE+ H QV + V+ +
Sbjct: 355 ENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSF-----WS 409
Query: 57 FHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDE 116
F A Q VY+ PLLE FEGFN +FAYGQTGSGK+YTM S +E
Sbjct: 410 FDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFS------EE 463
Query: 117 QGIVPRAMAEAFKLIDENDLLDCLVHV--SYLEVYKEEFRDLL----EVGTASRDIQLRE 170
GI+PR + F + + H+ S+ EVY E+ DLL E G + +++RE
Sbjct: 464 PGIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVRE 523
Query: 171 DERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGR 230
+ + V ++ S LE+GN R T AT +N SSRSH+VFT+ + Q
Sbjct: 524 HPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQT-- 581
Query: 231 APSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALG 290
+ + S+ + +DLAGSER + G+RLKE + IN SLL LG VISAL
Sbjct: 582 KTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALS 641
Query: 291 DP-QRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNI 349
+ +R IPYR+S +T +LK+SLGGN+KT MIA +SP++S+ +ETL+TL YA++A+ I
Sbjct: 642 EQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLI 701
Query: 350 RNRATVN 356
N A VN
Sbjct: 702 VNIAKVN 708
Score = 43.1 bits (100), Expect = 0.002
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 31/185 (16%)
Query: 745 IRELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKK 804
I E ++ E + EL QR E E KE Q + +Q +Q+ KE
Sbjct: 917 ISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQG-----------IQIAKEMA 965
Query: 805 QATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVK 864
Q + L S A E +++ LE LREE+++K+ E K H+++
Sbjct: 966 Q--QELSSQKAAYESKIKALEAE--------------LREESQRKKMQEINNQKANHKIE 1009
Query: 865 ELE--LKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKV 922
ELE +H +Q+ + K E+ K ++ + S+ + +E +K+ + +E++ +
Sbjct: 1010 ELEKAKQHLEQEIYVNKKRLEMETLATK-QALEDHSIRHARILEALETEKQKIAKEVQ-I 1067
Query: 923 LQQRR 927
LQQ R
Sbjct: 1068 LQQNR 1072
Score = 32.0 bits (71), Expect = 4.1
Identities = 25/125 (20%), Positives = 59/125 (47%), Gaps = 9/125 (7%)
Query: 905 QQKIEEQKKWLDQEMEKVLQ--QRRALEELGEELHKREAILAKKEALMQEKTGLESKRLR 962
+ +I+E + +EM + +Q + A +EL + E+ + EA ++E++ + +
Sbjct: 940 EAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEI 999
Query: 963 SSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGE-------IDSLRQEKD 1015
++Q N I + +HLE+E+ +L + ++Q + +++L EK
Sbjct: 1000 NNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQ 1059
Query: 1016 SLLKQ 1020
+ K+
Sbjct: 1060 KIAKE 1064
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 207 bits (527), Expect = 5e-53
Identities = 135/367 (36%), Positives = 201/367 (54%), Gaps = 27/367 (7%)
Query: 14 APVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRD-----RHFGFHV-----VLAE 63
A V+VA+RVRP +E + +Q++ + ++ + F F E
Sbjct: 4 ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPE 63
Query: 64 D---AGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIV 120
D A Q VY + +L FEG+N +FAYGQTG+GK+YTM + E + GI+
Sbjct: 64 DPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTM----MGKQEESQAGII 119
Query: 121 PRAMAEAFKLIDEN--DLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVL 178
P+ E F+ I++N + + V VSY+E+Y E RDLL ++++RE +
Sbjct: 120 PQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKG-NLRVREHPLLGPYV 178
Query: 179 CGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRP 238
+ ++ V ++ L++ GN AR AT++N SSRSH VFT+ Q+
Sbjct: 179 EDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLST 238
Query: 239 APGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGD---PQRR 295
VSK VDLAGSER TG+ G RLKE IN SL LG VISAL + +++
Sbjct: 239 EK----VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKK 294
Query: 296 GSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATV 355
IPYRDS +T +L+++LGGN++T M+A +SP+ ++DETL+TL YA RA+ I+ A +
Sbjct: 295 TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVI 354
Query: 356 NWRPEAE 362
N P A+
Sbjct: 355 NEDPNAK 361
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 207 bits (527), Expect = 5e-53
Identities = 135/367 (36%), Positives = 201/367 (54%), Gaps = 27/367 (7%)
Query: 14 APVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRD-----RHFGFHV-----VLAE 63
A V+VA+RVRP +E + +Q++ + ++ + F F E
Sbjct: 4 ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPE 63
Query: 64 D---AGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIV 120
D A Q VY + +L FEG+N +FAYGQTG+GK+YTM + E + GI+
Sbjct: 64 DPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTM----MGKQEESQAGII 119
Query: 121 PRAMAEAFKLIDEN--DLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVL 178
P+ E F+ I++N + + V VSY+E+Y E RDLL ++++RE +
Sbjct: 120 PQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKG-NLRVREHPLLGPYV 178
Query: 179 CGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRP 238
+ ++ V ++ L++ GN AR AT++N SSRSH VFT+ Q+
Sbjct: 179 EDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLST 238
Query: 239 APGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGD---PQRR 295
VSK VDLAGSER TG+ G RLKE IN SL LG VISAL + +++
Sbjct: 239 EK----VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKK 294
Query: 296 GSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATV 355
IPYRDS +T +L+++LGGN++T M+A +SP+ ++DETL+TL YA RA+ I+ A +
Sbjct: 295 TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVI 354
Query: 356 NWRPEAE 362
N P A+
Sbjct: 355 NEDPNAK 361
Score = 33.5 bits (75), Expect = 1.4
Identities = 54/244 (22%), Positives = 104/244 (42%), Gaps = 39/244 (15%)
Query: 763 QRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQ 822
QR+L E +G +++ E+ RLQE ++ KEK++A L E +LQ
Sbjct: 617 QRELLEKQGIDMKQEMEK-RLQEM---------EILYKKEKEEADLLLEQQRLDYESKLQ 666
Query: 823 ELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTE 882
L++ V+ R L ET ++ E E+ QH E EL Q K K+
Sbjct: 667 ALQKQVE---------TRSLAAETTEEEEEEEEVPWTQH---EFEL---AQWAFRKWKSH 711
Query: 883 EIAAFQRKRRSGS----NGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHK 938
+ + + + + +S+E ++K++ Q L + L E L E+ K
Sbjct: 712 QFTSLRDLLWGNAVYLKEANAISVELKKKVQFQFVLLTDTLYSPLPP----ELLPTEMEK 767
Query: 939 REAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQ 998
+ + +E + L++ + ++ RL+ L +E+ +++G++ SAQ
Sbjct: 768 TH----EDRPFPRTVVAVEVQDLKNGATHYWSLEKLKQRLD-LMREMYDRAGEM-ASSAQ 821
Query: 999 SQQQ 1002
+ +
Sbjct: 822 DESE 825
Score = 32.0 bits (71), Expect = 4.1
Identities = 15/56 (26%), Positives = 35/56 (62%), Gaps = 4/56 (7%)
Query: 1142 LERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKEL 1197
LE+Q ++M +++ ++ Q M++L ++ ++ L R YE+++QAL+K++
Sbjct: 621 LEKQGIDMKQEM----EKRLQEMEILYKKEKEEADLLLEQQRLDYESKLQALQKQV 672
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 207 bits (527), Expect = 5e-53
Identities = 148/390 (37%), Positives = 208/390 (53%), Gaps = 30/390 (7%)
Query: 9 PGAEEAPVRVALRVRPLLPKE-LLHGHQS-CLQV--EPGLGRVTLGRDRHFGFHVVLAED 64
P E ++V +R+RP + G Q+ CL V L + + F F V D
Sbjct: 20 PSNEGDAIKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLHSNPEPKTFTFDHVADVD 79
Query: 65 AGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLLEDEQGIVPRA 123
QE+V+ + ++E+ G+N T+FAYGQTGSGKT+TM G + + + +G++PR+
Sbjct: 80 TTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRS 139
Query: 124 MAEAFKLIDENDLL-----DCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVL 178
F LID L S++E+Y E+ DLL+ +AS + LRE + V +
Sbjct: 140 FEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLD--SASAGLYLREHIKKGVFV 197
Query: 179 CGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRP 238
G E V E +L G R +T +N SSRSH VFT+T+E ++ +
Sbjct: 198 VGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIV--- 254
Query: 239 APGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQR-RGS 297
+ S + VDLAGSER T + G RLKE+ IN SL LG VI+AL D +
Sbjct: 255 ---NIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQR 311
Query: 298 HIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN- 356
H+ YRDSK+T +L+DSLGGNAKT +IA V P S F ETL+TLN+A RA+ I+N+A VN
Sbjct: 312 HVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNE 371
Query: 357 --------WRPEAERPPEETASGARG--PP 376
+ E +R E+ A A G PP
Sbjct: 372 DTQGNVSQLQAEVKRLKEQLAELASGQTPP 401
Score = 59.7 bits (143), Expect = 2e-08
Identities = 129/645 (20%), Positives = 244/645 (37%), Gaps = 146/645 (22%)
Query: 710 IRELAINIRMKEELIGELVRTGKAAQALN--RQHSQRIRELE--QEAEQVRAE-LSEGQR 764
+ EL I+ E I R K A + R+ ++R+R LE + A+++ A+ +++ ++
Sbjct: 490 LSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKRAQEMDAQTIAKLEK 549
Query: 765 QLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQEL 824
E+ G E D + Q F + AQ + + ++ +L+ + + QE
Sbjct: 550 AFSEISGMEKSDKNQ----QGFSPK---AQKEPCLFANTEKLKAQLLQIQTELNNSKQEY 602
Query: 825 ERNVQLMRQQQGQLQRRLRE----ETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIK 880
E +L R++Q +L+ L+ + LEA + ++ V +L H + KI+
Sbjct: 603 EEFKELTRKRQLELESELQSLQKANLNLENLLEATKACKRQEVSQLNKIHAETLKIITTP 662
Query: 881 TEEIAAFQRK--RRSGSNGSVVSLEQQQKI----------------EEQKKWLDQEMEKV 922
T+ R + S GS SL Q E+ + + +E+ V
Sbjct: 663 TKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPPEMNEQAFEAISEELRTV 722
Query: 923 LQQRRALE-ELGEELHKREAILAKKEALMQEKTGLES----------------------- 958
+Q AL+ +L EE HK + + L T ++
Sbjct: 723 QEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVL 782
Query: 959 -KRLRSSQALNE----DIVRVSSRLEHLEKELSE--------KSGQLRQGSAQSQQQ--I 1003
K+L+ +Q N+ ++ + L +KELS K+ Q ++ + S++ +
Sbjct: 783 EKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHV 842
Query: 1004 RGEIDSLRQEKDSLLKQR---------------LEIDGKLRQGSLLSPEEERTLFQLDEA 1048
+ ++D+LR E + LL+ + EID R E E L+
Sbjct: 843 QLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNL 902
Query: 1049 IEALDAAIEYKN---------------EAITCRQRVLRASASLLSQCEMNLMAKLSYLSS 1093
+E L+A E N E + + V + ++CE MAK+ L
Sbjct: 903 MELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQ-MAKVQKLEE 961
Query: 1094 S------------------------------ETRALLCKYFDKVVTLREEQHQQQIAFSE 1123
S E R +C+ + + TL++E ++
Sbjct: 962 SLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNS 1021
Query: 1124 LEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSR 1183
+ EE + L+ EV + +D + TL+ + ++++ RD L E LA +
Sbjct: 1022 ALVDREESRVLIKKQEVDI------LDLKETLRLRILSEDIE------RDMLCEDLAHAT 1069
Query: 1184 RQYEARIQALEKELGRYMWINQELKQKLGGVNAVGHSRGGEKRSL 1228
Q +A +K G +EL +K + + H +K +
Sbjct: 1070 EQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEV 1114
Score = 54.3 bits (129), Expect = 8e-07
Identities = 60/317 (18%), Positives = 145/317 (45%), Gaps = 34/317 (10%)
Query: 738 NRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQV 797
+++HS ++ ++E + A + E Q +L + + + Q + E+ ++ + +
Sbjct: 1079 SKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQ------KKNEYNFKMRQLEHVM 1132
Query: 798 QVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMS 857
E Q+ + K L+ E+ ++ R + L+ + + E + AE+
Sbjct: 1133 DSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEIL 1192
Query: 858 KRQHRVKELE-LKHEQQQKILK--IKTEEIAAFQRKRRSGS----NGSVVSLEQQQKIEE 910
+ + +++E+E L+ E QQ I K + ++ +R++ + + + EQ++ I+E
Sbjct: 1193 RMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKE 1252
Query: 911 QKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNED 970
+ + +E++L+ + LEE+ L+ +E + ++ LESK + + L
Sbjct: 1253 RLA-KSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLR-- 1309
Query: 971 IVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSL-----LKQRLEID 1025
S+LE + +E R+ ++Q + +R +++ L +E L L Q+++
Sbjct: 1310 -----SKLEEMYEE--------RERTSQEMEMLRKQVECLAEENGKLVGHQNLHQKIQYV 1356
Query: 1026 GKLRQGSLLSPEEERTL 1042
+L++ ++ EE L
Sbjct: 1357 VRLKKENVRLAEETEKL 1373
Score = 53.1 bits (126), Expect = 2e-06
Identities = 100/510 (19%), Positives = 220/510 (43%), Gaps = 70/510 (13%)
Query: 756 RAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQAT-ERLVSLS 814
+A L + L+E+ E+ LQ F++ +S + L E +A ER LS
Sbjct: 860 KACLQDSYDNLQEIMKFEIDQLSRN--LQNFKKENETLKSDLNNLMELLEAEKERNNKLS 917
Query: 815 AQ----SEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKH 870
Q E +E+ + ++ +RQ++ + + ++ + ++LE + + + LE
Sbjct: 918 LQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSR 977
Query: 871 EQQQKILKI--------------KTEEIAAFQRKRRSGS---NGSVVSLEQQQKIEEQKK 913
+ +K++ KTE I +++ + + N ++V E+ + + ++++
Sbjct: 978 DSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQE 1037
Query: 914 WLDQEMEKVLQQRRALEELGEELHKREAILAKKEA-LMQEKTGLESKRLRSSQALNEDIV 972
++++ L+ R E++ ++ + A ++ ++ E + S L+S+Q E++
Sbjct: 1038 VDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQ---EELT 1094
Query: 973 RVSSRLEHLEKELSEKSGQLRQGSAQ---SQQQIRGEIDSLRQEKDS------------- 1016
+ + ++ L+ +L++K ++ Q + +Q+ +DS ++ S
Sbjct: 1095 KKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAK 1154
Query: 1017 -LLKQRLEI-DGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASA 1074
L Q EI DG+ + SL E + +L+E E +A I E + + LR +
Sbjct: 1155 LLETQEQEIEDGRASKTSL-----EHLVTKLNEDREVKNAEILRMKEQLREMEN-LRLES 1208
Query: 1075 SLLSQCEMNLMAKLSYLS-SSETRALLCKYFDKVVTLREEQHQQQIAFSEL-------EM 1126
L + L +L + E ++ +EE ++++A S++ +
Sbjct: 1209 QQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKA 1268
Query: 1127 QLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLL-----LQQSRDHLGEGLAD 1181
LEE Q +Y E+ R E++R TL+ K ++ QL + + R+ + +
Sbjct: 1269 DLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEM 1328
Query: 1182 SRRQYEARIQALEKELGRYMWINQELKQKL 1211
R+Q E + K +G +Q L QK+
Sbjct: 1329 LRKQVECLAEENGKLVG-----HQNLHQKI 1353
Score = 39.3 bits (90), Expect = 0.026
Identities = 64/312 (20%), Positives = 137/312 (43%), Gaps = 44/312 (14%)
Query: 894 GSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRA-LEELGEELHKREAILAKKEALMQE 952
G S ++ Q+ K+ + K ++++ + + Q +A ++ L E+L A LA + +
Sbjct: 348 GETLSTLNFAQRAKLIKNKAVVNEDTQGNVSQLQAEVKRLKEQL----AELASGQTPPES 403
Query: 953 KTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQ 1012
+ K+ + E ++ + E +K L EK QL + + ++ I+ ++
Sbjct: 404 FLTRDKKKTNYMEYFQEAML-FFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKF 462
Query: 1013 EKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEY---------KNEAI 1063
+D ++ RLE K +G L E++R L +L I+ L IE+ +N ++
Sbjct: 463 REDQII--RLEKLHKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSL 520
Query: 1064 TCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSE 1123
R LR + EM+ ++T A L K F ++ + + QQ FS
Sbjct: 521 REENRRLRLLEPVKRAQEMD----------AQTIAKLEKAFSEISGMEKSDKNQQ-GFS- 568
Query: 1124 LEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSR 1183
+++ ++ L+ Q L++ +L ++E+E+ +L ++ +
Sbjct: 569 ---PKAQKEPCLFANTEKLKAQLLQIQTELNNSKQEYEEFKELTRKR------------Q 613
Query: 1184 RQYEARIQALEK 1195
+ E+ +Q+L+K
Sbjct: 614 LELESELQSLQK 625
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,774,212
Number of Sequences: 37866
Number of extensions: 2725241
Number of successful extensions: 30954
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 535
Number of HSP's successfully gapped in prelim test: 1320
Number of HSP's that attempted gapping in prelim test: 12217
Number of HSP's gapped (non-prelim): 9097
length of query: 1343
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1229
effective length of database: 13,930,794
effective search space: 17120945826
effective search space used: 17120945826
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.