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Search of human proteins with 20162570
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20162570 melanoma antigen family E, 2 [Homo sapiens]
(523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20162570 melanoma antigen family E, 2 [Homo sapiens] 1053 0.0
gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 367 e-101
gi|20162572 necdin-like 2 [Homo sapiens] 160 2e-39
gi|27734781 melanoma antigen family B, 18 [Homo sapiens] 153 3e-37
gi|148746206 MAGE-like protein 2 [Homo sapiens] 153 3e-37
gi|153791873 melanoma antigen family B, 16 [Homo sapiens] 148 1e-35
gi|89276766 trophinin isoform 5 [Homo sapiens] 147 2e-35
gi|29540551 trophinin isoform 2 [Homo sapiens] 147 2e-35
gi|29540541 trophinin isoform 2 [Homo sapiens] 147 2e-35
gi|29171705 melanoma antigen family D, 2 [Homo sapiens] 146 4e-35
gi|19387846 melanoma antigen family D, 2 [Homo sapiens] 146 4e-35
gi|41350320 melanoma antigen family D, 2 [Homo sapiens] 146 4e-35
gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens] 145 7e-35
gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens] 145 7e-35
gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens] 145 7e-35
gi|29826296 melanoma antigen family F, 1 [Homo sapiens] 144 3e-34
gi|222418639 melanoma antigen family B, 2 [Homo sapiens] 143 4e-34
gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens] 141 1e-33
gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens] 141 1e-33
gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens] 141 1e-33
gi|149274614 melanoma antigen family D, 4 [Homo sapiens] 141 1e-33
gi|73623441 melanoma antigen family B, 10 [Homo sapiens] 140 3e-33
gi|58530863 melanoma antigen family A, 10 [Homo sapiens] 139 8e-33
gi|10567820 melanoma antigen family A, 10 [Homo sapiens] 139 8e-33
gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens] 138 1e-32
gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens] 138 1e-32
gi|29171714 melanoma antigen family B, 3 [Homo sapiens] 137 2e-32
gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo sapi... 133 5e-31
gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo sapi... 133 5e-31
gi|169216802 PREDICTED: melanoma antigen family B, 17 [Homo sapi... 133 5e-31
>gi|20162570 melanoma antigen family E, 2 [Homo sapiens]
Length = 523
Score = 1053 bits (2723), Expect = 0.0
Identities = 523/523 (100%), Positives = 523/523 (100%)
Query: 1 MSLVSQNARHCSAEITADYGDGRGEIQATNASGSPTSMLVVDAPQCPQAPINSQCVNTSQ 60
MSLVSQNARHCSAEITADYGDGRGEIQATNASGSPTSMLVVDAPQCPQAPINSQCVNTSQ
Sbjct: 1 MSLVSQNARHCSAEITADYGDGRGEIQATNASGSPTSMLVVDAPQCPQAPINSQCVNTSQ 60
Query: 61 AVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFLRE 120
AVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFLRE
Sbjct: 61 AVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFLRE 120
Query: 121 YSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLL 180
YSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLL
Sbjct: 121 YSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLL 180
Query: 181 ALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWP 240
ALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWP
Sbjct: 181 ALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWP 240
Query: 241 VYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALEGDKTKERSLT 300
VYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALEGDKTKERSLT
Sbjct: 241 VYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALEGDKTKERSLT 300
Query: 301 AGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLIL 360
AGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLIL
Sbjct: 301 AGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLIL 360
Query: 361 DMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKE 420
DMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKE
Sbjct: 361 DMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKE 420
Query: 421 ANVWNLLRRFSVDVGRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKV 480
ANVWNLLRRFSVDVGRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKV
Sbjct: 421 ANVWNLLRRFSVDVGRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKV 480
Query: 481 LEYMARLYRKRPQNWPEQYREAVEDEEARAKSEATIMFFLDPT 523
LEYMARLYRKRPQNWPEQYREAVEDEEARAKSEATIMFFLDPT
Sbjct: 481 LEYMARLYRKRPQNWPEQYREAVEDEEARAKSEATIMFFLDPT 523
>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
Length = 957
Score = 367 bits (943), Expect = e-101
Identities = 195/502 (38%), Positives = 296/502 (58%), Gaps = 38/502 (7%)
Query: 42 DAPQCPQAPINSQCVNTSQAVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRM 101
+ P+ + PI + + ++ PN + ++ SR L+ DP+E L+ F+ +
Sbjct: 448 EGPKGAEGPIEFEVLRDCES---PNSISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLV 504
Query: 102 KSQTEGSIQQSEMLEFL-REYSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKR 160
K Q++ I++SEM E++ +EY +QFPEILRRA+AHL+ +F LR +DP+A TY L++K
Sbjct: 505 KDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELDPEAHTYILLNKL 564
Query: 161 GFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFG 220
G + + ES + PK LL ++LG I LNGN+A+EA IW++L ++ + + +R ++FG
Sbjct: 565 GPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGV--QRERRLSIFG 622
Query: 221 NTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWS 280
N + LL+ +FV R+L+Y PV P+E+EF WG R+H E TKM+ LKF++ ++++P
Sbjct: 623 NPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMD 682
Query: 281 WPEEYNKALEGDKTK--------------------------------ERSLTAGLEFWSE 308
WPE+YN+ALE D + S W E
Sbjct: 683 WPEKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPE 742
Query: 309 DTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSL 368
+ KA LVQL + + LPI + +L + G+E VFP++LNRA L+ YG L
Sbjct: 743 SRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTEL 802
Query: 369 IEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLR 428
+ +D H Y L + E EE + +++S RP ++M +L IF+MGN +E+ VW LR
Sbjct: 803 VVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLR 862
Query: 429 RFSVDVGRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLEYMARLY 488
V GRKH IT + + QRY++ + S+PV+YE +WGPRA ET KMK L Y+AR++
Sbjct: 863 GLGVQAGRKHVITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALRYVARIH 922
Query: 489 RKRPQNWPEQYREAVEDEEARA 510
RK PQ+WP+QYREA+EDE RA
Sbjct: 923 RKEPQDWPQQYREAMEDEANRA 944
Score = 156 bits (395), Expect = 4e-38
Identities = 81/214 (37%), Positives = 123/214 (57%), Gaps = 8/214 (3%)
Query: 308 EDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLS 367
+D M +L+Q + + PI + E+ + KE+ + FP IL RA L+ +
Sbjct: 488 QDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFE 547
Query: 368 LIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLL 427
L E+D H Y+L+ + + + ES P +M ILG IFL GN+ KEA +W +L
Sbjct: 548 LRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEML 607
Query: 428 --------RRFSVDVGRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMK 479
RR S+ K ++ + + QRYL+ RP++ PVEYE WGPR+H ET KMK
Sbjct: 608 WRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMK 667
Query: 480 VLEYMARLYRKRPQNWPEQYREAVEDEEARAKSE 513
+L++MA++Y K P +WPE+Y EA+E++ ARA +E
Sbjct: 668 ILKFMAKIYNKDPMDWPEKYNEALEEDAARAFAE 701
Score = 34.7 bits (78), Expect = 0.22
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query: 1 MSLVSQNARHCSAEIT--ADYGDGRGEIQATNASGSPTSMLVVDAPQCPQAPINSQCVNT 58
MSLVSQN+R + + GE+QA NA G P V PQ P +SQ +
Sbjct: 1 MSLVSQNSRRRRRRVAKATAHNSSWGEMQAPNAPGLPAD---VPGSDVPQGPSDSQILQG 57
Query: 59 SQAVQDPN 66
A + P+
Sbjct: 58 LCASEGPS 65
>gi|20162572 necdin-like 2 [Homo sapiens]
Length = 304
Score = 160 bits (406), Expect = 2e-39
Identities = 81/216 (37%), Positives = 131/216 (60%), Gaps = 9/216 (4%)
Query: 307 SEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGL 366
S+ + K ++LVQ + ++ +PI + ++L H +++D+FP++ RA L +G
Sbjct: 81 SQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIGDYKDIFPDLFKRAAERLQYVFGY 140
Query: 367 SLIEVDTSEHIYLLVQQPES-EEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWN 425
L+E++ + Y+L+ E EE+ M G PT +M +LGLIF+ GN +KE W+
Sbjct: 141 KLVELEPKSNTYILINTLEPVEEDAEMRGDQGTPTTGLLMIVLGLIFMKGNTIKETEAWD 200
Query: 426 LLRRFSVDVGRKHSI--------TRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIK 477
LRR V +KH I T +RQRYLE R + +++PV+YE WGPR + ET K
Sbjct: 201 FLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTDPVDYEFQWGPRTNLETSK 260
Query: 478 MKVLEYMARLYRKRPQNWPEQYREAVEDEEARAKSE 513
MKVL+++A+++ + P++WP QY EA+ DEE RA+ +
Sbjct: 261 MKVLKFVAKVHNQDPKDWPAQYCEALADEENRARPQ 296
Score = 143 bits (360), Expect = 4e-34
Identities = 83/262 (31%), Positives = 147/262 (56%), Gaps = 15/262 (5%)
Query: 48 QAPINSQCVNTSQAVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEG 107
+AP S+ SQ Q P+ + + +G R LE + LV F+ +K Q +
Sbjct: 46 EAPSTSRGPGGSQGSQGPSPQGARRAQAAPAVGP-RSQKQLELKVSELVQFLLIKDQKKI 104
Query: 108 SIQQSEMLEF-LREYSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITD 166
I+++++L+ + +Y D FP++ +RA+ L VFG L ++P+++TY L++ +
Sbjct: 105 PIKRADILKHVIGDYKDIFPDLFKRAAERLQYVFGYKLVELEPKSNTYILINT-----LE 159
Query: 167 RIAESLDM------PKASLLALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFG 220
+ E +M P LL +VLG I + GN +E WD L ++ ++ P + + +FG
Sbjct: 160 PVEEDAEMRGDQGTPTTGLLMIVLGLIFMKGNTIKETEAWDFLRRLGVY--PTKKHLIFG 217
Query: 221 NTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWS 280
+ + L+T DFV R+LEY + T+P+++EF WG R + E +KM+ LKFV+ H+++P
Sbjct: 218 DPKKLITEDFVRQRYLEYRRIPHTDPVDYEFQWGPRTNLETSKMKVLKFVAKVHNQDPKD 277
Query: 281 WPEEYNKALEGDKTKERSLTAG 302
WP +Y +AL ++ + R +G
Sbjct: 278 WPAQYCEALADEENRARPQPSG 299
>gi|27734781 melanoma antigen family B, 18 [Homo sapiens]
Length = 343
Score = 153 bits (387), Expect = 3e-37
Identities = 91/296 (30%), Positives = 157/296 (53%), Gaps = 20/296 (6%)
Query: 24 GEIQATNASGS------------PTSMLVVDAPQCPQAPINSQCVNTSQAVQDPNDLEVL 71
G QAT A G P ++ + P P+A + + A + E
Sbjct: 26 GATQATVAEGESPSSAYLLFGDRPQNLPAAETPSIPEALQGAPSTTNAIAPVSCSSNEGA 85
Query: 72 IDEQSRRLGALRV-----HDPLEDRSIALVNFMRMKSQTEGSIQQSEMLEF-LREYSDQF 125
+ + LG+ R DPL + ++LV+F+ K +T+ I + +M++F +R+ F
Sbjct: 86 SSQDEKSLGSSREAEGWKEDPLNKKVVSLVHFLLQKYETKEPITKGDMIKFVIRKDKCHF 145
Query: 126 PEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLG 185
EIL+RAS H++ G++L+ +DP Y SK + ++ +PK LL + LG
Sbjct: 146 NEILKRASEHMELALGVDLKEVDPIRHYYAFFSKLDLTYDETTSDEEKIPKTGLLMIALG 205
Query: 186 HILLNGNRAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTN 245
I LNGNRA E ++W+++ + ++ R + L+G+ R ++T D V +++LEY V ++
Sbjct: 206 VIFLNGNRAPEEAVWEIMNMMGVY--ADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPNSD 263
Query: 246 PLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALEGDKTKERSLTA 301
P +EFLWG RAH E +KM+ L+FV+ HD P ++P Y +AL ++ + ++ A
Sbjct: 264 PPRYEFLWGPRAHAETSKMKVLEFVAKIHDTVPSAFPSCYEEALRDEEQRTQARAA 319
Score = 132 bits (332), Expect = 8e-31
Identities = 77/237 (32%), Positives = 119/237 (50%), Gaps = 8/237 (3%)
Query: 286 NKALEGDKTKERSLTAGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEF 345
N+ K + E W ED +N K LV + E PI + +++ ++
Sbjct: 82 NEGASSQDEKSLGSSREAEGWKEDPLNKKVVSLVHFLLQKYETKEPITKGDMIKFVIRKD 141
Query: 346 EDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVM 405
+ F IL RA+ +++ G+ L EVD H Y + + ++ + P +M
Sbjct: 142 KCHFNEILKRASEHMELALGVDLKEVDPIRHYYAFFSKLDLTYDETTSDEEKIPKTGLLM 201
Query: 406 PILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHSI--------TRKLMRQRYLECRPLSY 457
LG+IFL GNR E VW ++ V RKH + T+ L++ +YLE + +
Sbjct: 202 IALGVIFLNGNRAPEEAVWEIMNMMGVYADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPN 261
Query: 458 SNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREAVEDEEARAKSEA 514
S+P YE LWGPRAH ET KMKVLE++A+++ P +P Y EA+ DEE R ++ A
Sbjct: 262 SDPPRYEFLWGPRAHAETSKMKVLEFVAKIHDTVPSAFPSCYEEALRDEEQRTQARA 318
>gi|148746206 MAGE-like protein 2 [Homo sapiens]
Length = 646
Score = 153 bits (387), Expect = 3e-37
Identities = 83/204 (40%), Positives = 126/204 (61%), Gaps = 3/204 (1%)
Query: 87 PLEDRSIALVNFMRMKSQTEGSIQQSEMLE-FLREYSDQFPEILRRASAHLDQVFGLNLR 145
PL++R+ ALV F+ +K Q + +Q+SEM++ LREY D+ +I+ RA+ L+ FG L+
Sbjct: 416 PLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLK 475
Query: 146 VIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLK 205
ID + Y +++K G+ + +A LD PK LL +VL I + GN RE I++ L K
Sbjct: 476 EIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFK 535
Query: 206 VDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKME 265
+ + + N LFGNT+ L+T FV ++LEY + T P E+EFLWG RA E +KM
Sbjct: 536 LGL--DVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKML 593
Query: 266 ALKFVSDAHDEEPWSWPEEYNKAL 289
L+F++ H ++P SWP Y +AL
Sbjct: 594 VLRFLAKLHKKDPQSWPFHYLEAL 617
Score = 140 bits (352), Expect = 4e-33
Identities = 74/205 (36%), Positives = 119/205 (58%), Gaps = 8/205 (3%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
++++AN LVQ + + +P+ + E++ +E++D +I+NRA L+ +G L E
Sbjct: 417 LDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKE 476
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+DT H Y+++ + ++ L RP +M +L LIF+ GN V+E ++N L +
Sbjct: 477 IDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKL 536
Query: 431 SVDV--------GRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+DV K IT +RQ+YLE R + Y+ P EYE LWGPRA ET KM VL
Sbjct: 537 GLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLR 596
Query: 483 YMARLYRKRPQNWPEQYREAVEDEE 507
++A+L++K PQ+WP Y EA+ + E
Sbjct: 597 FLAKLHKKDPQSWPFHYLEALAECE 621
>gi|153791873 melanoma antigen family B, 16 [Homo sapiens]
Length = 324
Score = 148 bits (373), Expect = 1e-35
Identities = 79/214 (36%), Positives = 124/214 (57%), Gaps = 3/214 (1%)
Query: 86 DPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFL-REYSDQFPEILRRASAHLDQVFGLNL 144
D L+ + LVNFM K Q + I +++ML+ + ++ F EIL RAS HL+ +FGL++
Sbjct: 111 DALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKDDESHFSEILLRASEHLEMIFGLDV 170
Query: 145 RVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLL 204
+DP Y L K G ++ +PK LL +VLG I + GNRA E +W++L
Sbjct: 171 VEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLLIIVLGVIFMKGNRATEEEVWEVLN 230
Query: 205 KVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKM 264
++ + +FG R L+T DFV ++LEY V ++P +EFLWG RA E +KM
Sbjct: 231 LTGVYSGKKHF--IFGEPRMLITKDFVKEKYLEYQQVANSDPARYEFLWGPRAKAETSKM 288
Query: 265 EALKFVSDAHDEEPWSWPEEYNKALEGDKTKERS 298
+ L+FV+ H P S+P +Y +AL+ ++ + R+
Sbjct: 289 KVLEFVAKVHGSYPHSFPSQYAEALKEEEERARA 322
Score = 136 bits (343), Expect = 4e-32
Identities = 83/250 (33%), Positives = 135/250 (54%), Gaps = 15/250 (6%)
Query: 271 SDAHDEEPWSWPEEYNKALEGDKTKERSLTAGLEFWSEDTMNDKANDLVQLAISVTEEML 330
S DE + EE + + D + R++ A D ++ K LV + +
Sbjct: 80 SSESDEASSNQEEEDSPSSSEDTSDPRNVPA-------DALDQKVAFLVNFMLHKCQMKK 132
Query: 331 PIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQ 390
PI + ++L K+ E F IL RA+ L+M +GL ++EVD + H Y L + +
Sbjct: 133 PITKADMLKIIIKDDESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDG 192
Query: 391 VMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHSI--------TR 442
++ G P ++ +LG+IF+ GNR E VW +L V G+KH I T+
Sbjct: 193 MLSGEKGVPKTGLLIIVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITK 252
Query: 443 KLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREA 502
++++YLE + ++ S+P YE LWGPRA ET KMKVLE++A+++ P ++P QY EA
Sbjct: 253 DFVKEKYLEYQQVANSDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEA 312
Query: 503 VEDEEARAKS 512
+++EE RA++
Sbjct: 313 LKEEEERARA 322
>gi|89276766 trophinin isoform 5 [Homo sapiens]
Length = 1431
Score = 147 bits (371), Expect = 2e-35
Identities = 78/204 (38%), Positives = 129/204 (63%), Gaps = 4/204 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L++R+ LV ++ +K QT+ I++S+ML + ++EY + FPEI+ RAS L+++F +NL+
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID Q+ Y L+S + + + D PK LL ++L I +NGN+A EA IW++L K+
Sbjct: 504 IDKQSSLYILISTQESS-AGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P ++LFG R L+T +FV ++LEY V + P E+EF WG R++ E +KM+
Sbjct: 563 GL--RPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKV 620
Query: 267 LKFVSDAHDEEPWSWPEEYNKALE 290
LKF ++P W +Y +A+E
Sbjct: 621 LKFACRVQKKDPKDWAVQYREAVE 644
Score = 141 bits (355), Expect = 2e-33
Identities = 76/221 (34%), Positives = 128/221 (57%), Gaps = 18/221 (8%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + + +PI + ++L +E+++ FP I+ RA+ L+ + ++L E
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D +Y+L+ ES ++ + P +M IL +IF+ GN+ EA +W +LR+
Sbjct: 504 IDKQSSLYILISTQESSAG-ILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +HS IT + ++Q+YLE + + S P EYE WG R++HET KMKVL+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 483 YMARLYRKRPQNWPEQYREAVEDE---------EARAKSEA 514
+ R+ +K P++W QYREAVE E EA A++EA
Sbjct: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEA 663
>gi|29540551 trophinin isoform 2 [Homo sapiens]
Length = 706
Score = 147 bits (371), Expect = 2e-35
Identities = 78/204 (38%), Positives = 129/204 (63%), Gaps = 4/204 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L++R+ LV ++ +K QT+ I++S+ML + ++EY + FPEI+ RAS L+++F +NL+
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID Q+ Y L+S + + + D PK LL ++L I +NGN+A EA IW++L K+
Sbjct: 504 IDKQSSLYILISTQESS-AGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P ++LFG R L+T +FV ++LEY V + P E+EF WG R++ E +KM+
Sbjct: 563 GL--RPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKV 620
Query: 267 LKFVSDAHDEEPWSWPEEYNKALE 290
LKF ++P W +Y +A+E
Sbjct: 621 LKFACRVQKKDPKDWAVQYREAVE 644
Score = 139 bits (351), Expect = 5e-33
Identities = 75/220 (34%), Positives = 127/220 (57%), Gaps = 18/220 (8%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + + +PI + ++L +E+++ FP I+ RA+ L+ + ++L E
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D +Y+L+ ES ++ + P +M IL +IF+ GN+ EA +W +LR+
Sbjct: 504 IDKQSSLYILISTQESSAG-ILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +HS IT + ++Q+YLE + + S P EYE WG R++HET KMKVL+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 483 YMARLYRKRPQNWPEQYREAVEDE---------EARAKSE 513
+ R+ +K P++W QYREAVE E EA A++E
Sbjct: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662
>gi|29540541 trophinin isoform 2 [Homo sapiens]
Length = 706
Score = 147 bits (371), Expect = 2e-35
Identities = 78/204 (38%), Positives = 129/204 (63%), Gaps = 4/204 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L++R+ LV ++ +K QT+ I++S+ML + ++EY + FPEI+ RAS L+++F +NL+
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID Q+ Y L+S + + + D PK LL ++L I +NGN+A EA IW++L K+
Sbjct: 504 IDKQSSLYILISTQESS-AGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P ++LFG R L+T +FV ++LEY V + P E+EF WG R++ E +KM+
Sbjct: 563 GL--RPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKV 620
Query: 267 LKFVSDAHDEEPWSWPEEYNKALE 290
LKF ++P W +Y +A+E
Sbjct: 621 LKFACRVQKKDPKDWAVQYREAVE 644
Score = 139 bits (351), Expect = 5e-33
Identities = 75/220 (34%), Positives = 127/220 (57%), Gaps = 18/220 (8%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + + +PI + ++L +E+++ FP I+ RA+ L+ + ++L E
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D +Y+L+ ES ++ + P +M IL +IF+ GN+ EA +W +LR+
Sbjct: 504 IDKQSSLYILISTQESSAG-ILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +HS IT + ++Q+YLE + + S P EYE WG R++HET KMKVL+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 483 YMARLYRKRPQNWPEQYREAVEDE---------EARAKSE 513
+ R+ +K P++W QYREAVE E EA A++E
Sbjct: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662
>gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 146 bits (369), Expect = 4e-35
Identities = 75/213 (35%), Positives = 128/213 (60%), Gaps = 9/213 (4%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ +ANDLV+ ++ + +PI + ++L KE+ DV+P I+ RA L+ +G+ L E
Sbjct: 279 LQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKE 338
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D ++H+Y+L+ E + ++ + P +M +L +IF+ GNR EA +W +LR+
Sbjct: 339 IDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKL 398
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G HS IT + ++Q+YL+ + SNP EYE WG R+++ET KMKVL+
Sbjct: 399 GLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLK 458
Query: 483 YMARLYRKRPQNWPEQYREAVE-DEEARAKSEA 514
+ ++ +K P+ W QYREA+E D +A A++ A
Sbjct: 459 FACKVQKKDPKEWAAQYREAMEADLKAAAEAAA 491
Score = 146 bits (369), Expect = 4e-35
Identities = 77/206 (37%), Positives = 127/206 (61%), Gaps = 3/206 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L+ R+ LV ++ K QT+ I++S+ML + ++EY+D +PEI+ RA L++VFG+ L+
Sbjct: 279 LQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKE 338
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID Y L+S + + D PK LL ++L I +NGNR+ EA IW++L K+
Sbjct: 339 IDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKL 398
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P ++LFG+ + L+T +FV ++L+Y V +NP E+EF WG R++ E +KM+
Sbjct: 399 GL--RPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKV 456
Query: 267 LKFVSDAHDEEPWSWPEEYNKALEGD 292
LKF ++P W +Y +A+E D
Sbjct: 457 LKFACKVQKKDPKEWAAQYREAMEAD 482
>gi|19387846 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 146 bits (369), Expect = 4e-35
Identities = 75/213 (35%), Positives = 128/213 (60%), Gaps = 9/213 (4%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ +ANDLV+ ++ + +PI + ++L KE+ DV+P I+ RA L+ +G+ L E
Sbjct: 279 LQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKE 338
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D ++H+Y+L+ E + ++ + P +M +L +IF+ GNR EA +W +LR+
Sbjct: 339 IDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKL 398
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G HS IT + ++Q+YL+ + SNP EYE WG R+++ET KMKVL+
Sbjct: 399 GLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLK 458
Query: 483 YMARLYRKRPQNWPEQYREAVE-DEEARAKSEA 514
+ ++ +K P+ W QYREA+E D +A A++ A
Sbjct: 459 FACKVQKKDPKEWAAQYREAMEADLKAAAEAAA 491
Score = 146 bits (369), Expect = 4e-35
Identities = 77/206 (37%), Positives = 127/206 (61%), Gaps = 3/206 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L+ R+ LV ++ K QT+ I++S+ML + ++EY+D +PEI+ RA L++VFG+ L+
Sbjct: 279 LQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKE 338
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID Y L+S + + D PK LL ++L I +NGNR+ EA IW++L K+
Sbjct: 339 IDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKL 398
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P ++LFG+ + L+T +FV ++L+Y V +NP E+EF WG R++ E +KM+
Sbjct: 399 GL--RPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKV 456
Query: 267 LKFVSDAHDEEPWSWPEEYNKALEGD 292
LKF ++P W +Y +A+E D
Sbjct: 457 LKFACKVQKKDPKEWAAQYREAMEAD 482
>gi|41350320 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 146 bits (369), Expect = 4e-35
Identities = 75/213 (35%), Positives = 128/213 (60%), Gaps = 9/213 (4%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ +ANDLV+ ++ + +PI + ++L KE+ DV+P I+ RA L+ +G+ L E
Sbjct: 279 LQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKE 338
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D ++H+Y+L+ E + ++ + P +M +L +IF+ GNR EA +W +LR+
Sbjct: 339 IDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKL 398
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G HS IT + ++Q+YL+ + SNP EYE WG R+++ET KMKVL+
Sbjct: 399 GLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLK 458
Query: 483 YMARLYRKRPQNWPEQYREAVE-DEEARAKSEA 514
+ ++ +K P+ W QYREA+E D +A A++ A
Sbjct: 459 FACKVQKKDPKEWAAQYREAMEADLKAAAEAAA 491
Score = 146 bits (369), Expect = 4e-35
Identities = 77/206 (37%), Positives = 127/206 (61%), Gaps = 3/206 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L+ R+ LV ++ K QT+ I++S+ML + ++EY+D +PEI+ RA L++VFG+ L+
Sbjct: 279 LQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKE 338
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID Y L+S + + D PK LL ++L I +NGNR+ EA IW++L K+
Sbjct: 339 IDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKL 398
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P ++LFG+ + L+T +FV ++L+Y V +NP E+EF WG R++ E +KM+
Sbjct: 399 GL--RPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKV 456
Query: 267 LKFVSDAHDEEPWSWPEEYNKALEGD 292
LKF ++P W +Y +A+E D
Sbjct: 457 LKFACKVQKKDPKEWAAQYREAMEAD 482
>gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]
Length = 834
Score = 145 bits (367), Expect = 7e-35
Identities = 77/221 (34%), Positives = 129/221 (58%), Gaps = 18/221 (8%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + +PI + E+L +E+ DV+P I+ RA +L+ +G+ L E
Sbjct: 527 LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKE 586
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D EH+Y+L+ PES ++ + P ++ ILG+IF+ GNR EA +W LR+
Sbjct: 587 IDKEEHLYILISTPESLAG-ILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 645
Query: 431 SVDVGRKHSI--------TRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H + T + ++Q+YL+ R + SNP EYE LWG R++HET KMKVL
Sbjct: 646 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 705
Query: 483 YMARLYRKRPQNWPEQYREAVED---------EEARAKSEA 514
++A + ++ P++W Q+ EA ++ EA A++EA
Sbjct: 706 FIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEA 746
Score = 145 bits (366), Expect = 9e-35
Identities = 80/218 (36%), Positives = 134/218 (61%), Gaps = 6/218 (2%)
Query: 76 SRRLGALRVHDP--LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRA 132
S+ GA + D L++R+ LV ++ +K T+ I++SEML + +REY+D +PEI+ RA
Sbjct: 513 SQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERA 572
Query: 133 SAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGN 192
L++ FG+ L+ ID + Y L+S + + + D PK LL ++LG I +NGN
Sbjct: 573 CFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGN 631
Query: 193 RAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFL 252
RA EA +W+ L K+ + +P + L G+ R LLT +FV ++L+Y V +NP E+EFL
Sbjct: 632 RASEAVLWEALRKMGL--RPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFL 689
Query: 253 WGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALE 290
WG R++ E +KM+ L+F+++ +P W ++ +A +
Sbjct: 690 WGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAAD 727
>gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]
Length = 778
Score = 145 bits (367), Expect = 7e-35
Identities = 77/221 (34%), Positives = 129/221 (58%), Gaps = 18/221 (8%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + +PI + E+L +E+ DV+P I+ RA +L+ +G+ L E
Sbjct: 471 LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKE 530
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D EH+Y+L+ PES ++ + P ++ ILG+IF+ GNR EA +W LR+
Sbjct: 531 IDKEEHLYILISTPESLAG-ILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 589
Query: 431 SVDVGRKHSI--------TRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H + T + ++Q+YL+ R + SNP EYE LWG R++HET KMKVL
Sbjct: 590 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 649
Query: 483 YMARLYRKRPQNWPEQYREAVED---------EEARAKSEA 514
++A + ++ P++W Q+ EA ++ EA A++EA
Sbjct: 650 FIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEA 690
Score = 145 bits (366), Expect = 9e-35
Identities = 80/218 (36%), Positives = 134/218 (61%), Gaps = 6/218 (2%)
Query: 76 SRRLGALRVHDP--LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRA 132
S+ GA + D L++R+ LV ++ +K T+ I++SEML + +REY+D +PEI+ RA
Sbjct: 457 SQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERA 516
Query: 133 SAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGN 192
L++ FG+ L+ ID + Y L+S + + + D PK LL ++LG I +NGN
Sbjct: 517 CFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGN 575
Query: 193 RAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFL 252
RA EA +W+ L K+ + +P + L G+ R LLT +FV ++L+Y V +NP E+EFL
Sbjct: 576 RASEAVLWEALRKMGL--RPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFL 633
Query: 253 WGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALE 290
WG R++ E +KM+ L+F+++ +P W ++ +A +
Sbjct: 634 WGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAAD 671
>gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]
Length = 778
Score = 145 bits (367), Expect = 7e-35
Identities = 77/221 (34%), Positives = 129/221 (58%), Gaps = 18/221 (8%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + +PI + E+L +E+ DV+P I+ RA +L+ +G+ L E
Sbjct: 471 LQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKE 530
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D EH+Y+L+ PES ++ + P ++ ILG+IF+ GNR EA +W LR+
Sbjct: 531 IDKEEHLYILISTPESLAG-ILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKM 589
Query: 431 SVDVGRKHSI--------TRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H + T + ++Q+YL+ R + SNP EYE LWG R++HET KMKVL
Sbjct: 590 GLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLR 649
Query: 483 YMARLYRKRPQNWPEQYREAVED---------EEARAKSEA 514
++A + ++ P++W Q+ EA ++ EA A++EA
Sbjct: 650 FIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEA 690
Score = 145 bits (366), Expect = 9e-35
Identities = 80/218 (36%), Positives = 134/218 (61%), Gaps = 6/218 (2%)
Query: 76 SRRLGALRVHDP--LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRA 132
S+ GA + D L++R+ LV ++ +K T+ I++SEML + +REY+D +PEI+ RA
Sbjct: 457 SQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERA 516
Query: 133 SAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGN 192
L++ FG+ L+ ID + Y L+S + + + D PK LL ++LG I +NGN
Sbjct: 517 CFVLEKKFGIQLKEIDKEEHLYILISTPE-SLAGILGTTKDTPKLGLLLVILGVIFMNGN 575
Query: 193 RAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFL 252
RA EA +W+ L K+ + +P + L G+ R LLT +FV ++L+Y V +NP E+EFL
Sbjct: 576 RASEAVLWEALRKMGL--RPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFL 633
Query: 253 WGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALE 290
WG R++ E +KM+ L+F+++ +P W ++ +A +
Sbjct: 634 WGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAAD 671
>gi|29826296 melanoma antigen family F, 1 [Homo sapiens]
Length = 307
Score = 144 bits (362), Expect = 3e-34
Identities = 87/247 (35%), Positives = 137/247 (55%), Gaps = 19/247 (7%)
Query: 76 SRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEMLEF-LREYSDQFPEILRRASA 134
++ L R + L LV F+ +K + + I +SEM+++ + + FP+I+ RA+
Sbjct: 64 AKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAE 123
Query: 135 HLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESL--DMPKASLLALVLGHILLNGN 192
HL VFG L+ D + TY L++K + + E L D P+ LL ++LG I + GN
Sbjct: 124 HLRYVFGFELKQFDRKHHTYILINKLK-PLEEEEEEDLGGDGPRLGLLMMILGLIYMRGN 182
Query: 193 RAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFL 252
AREA +W++L ++ + +P + + LFG + L+ DFV R+L Y V TNP E+EF
Sbjct: 183 SAREAQVWEMLRRLGV--QPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPEYEFS 240
Query: 253 WGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKAL--EGDKTKER-----------SL 299
WG R++ EI+KME L FV+ H +EP WP +Y +AL E D+ + + S
Sbjct: 241 WGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEADRARAKARAEASMRARASA 300
Query: 300 TAGLEFW 306
AG+ W
Sbjct: 301 RAGIHLW 307
Score = 143 bits (361), Expect = 3e-34
Identities = 80/214 (37%), Positives = 124/214 (57%), Gaps = 11/214 (5%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+N +LVQ + ++ PI + E++ + + + +FP+I+ RA L +G L +
Sbjct: 76 LNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQ 135
Query: 371 VDTSEHIYLLVQQ--PESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLR 428
D H Y+L+ + P EEE+ L G P +M ILGLI++ GN +EA VW +LR
Sbjct: 136 FDRKHHTYILINKLKPLEEEEEEDLGGDG-PRLGLLMMILGLIYMRGNSAREAQVWEMLR 194
Query: 429 RFSVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKV 480
R V + H I ++QRYL R + ++NP EYE WGPR++ E KM+V
Sbjct: 195 RLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPEYEFSWGPRSNLEISKMEV 254
Query: 481 LEYMARLYRKRPQNWPEQYREAVEDEEARAKSEA 514
L ++A+L++K PQ+WP QYREA+ DE RA+++A
Sbjct: 255 LGFVAKLHKKEPQHWPVQYREALADEADRARAKA 288
>gi|222418639 melanoma antigen family B, 2 [Homo sapiens]
Length = 319
Score = 143 bits (360), Expect = 4e-34
Identities = 79/230 (34%), Positives = 130/230 (56%), Gaps = 9/230 (3%)
Query: 287 KALEGDKTKERS-LTAGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEF 345
K+ +G+K S + + SED + K+ LVQ + + + + E+L GK F
Sbjct: 86 KSHQGEKNASSSQASTSTKSPSEDPLTRKSGSLVQFLLYKYKIKKSVTKGEMLKIVGKRF 145
Query: 346 EDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVM 405
+ FP IL +A+ L + +GL L +V+ + H Y + + + +E+ +L S P ++ +M
Sbjct: 146 REHFPEILKKASEGLSVVFGLELNKVNPNGHTYTFIDKVDLTDEESLLSSWDFPRRKLLM 205
Query: 406 PILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHS--------ITRKLMRQRYLECRPLSY 457
P+LG+IFL GN E +W L V G +HS IT+ L++++YLE + +
Sbjct: 206 PLLGVIFLNGNSATEEEIWEFLNMLGVYDGEEHSVFGEPWKLITKDLVQEKYLEYKQVPS 265
Query: 458 SNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREAVEDEE 507
S+P ++ LWGPRA+ ET KMKVLE++A++ P +P Y EA++DEE
Sbjct: 266 SDPPRFQFLWGPRAYAETSKMKVLEFLAKVNGTTPCAFPTHYEEALKDEE 315
Score = 141 bits (355), Expect = 2e-33
Identities = 75/209 (35%), Positives = 123/209 (58%), Gaps = 3/209 (1%)
Query: 86 DPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFL-REYSDQFPEILRRASAHLDQVFGLNL 144
DPL +S +LV F+ K + + S+ + EML+ + + + + FPEIL++AS L VFGL L
Sbjct: 109 DPLTRKSGSLVQFLLYKYKIKKSVTKGEMLKIVGKRFREHFPEILKKASEGLSVVFGLEL 168
Query: 145 RVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLL 204
++P TY + K + + S D P+ LL +LG I LNGN A E IW+ L
Sbjct: 169 NKVNPNGHTYTFIDKVDLTDEESLLSSWDFPRRKLLMPLLGVIFLNGNSATEEEIWEFLN 228
Query: 205 KVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKM 264
+ ++D + +++FG L+T D V ++LEY V ++P F+FLWG RA+ E +KM
Sbjct: 229 MLGVYDGEE--HSVFGEPWKLITKDLVQEKYLEYKQVPSSDPPRFQFLWGPRAYAETSKM 286
Query: 265 EALKFVSDAHDEEPWSWPEEYNKALEGDK 293
+ L+F++ + P ++P Y +AL+ ++
Sbjct: 287 KVLEFLAKVNGTTPCAFPTHYEEALKDEE 315
>gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]
Length = 739
Score = 141 bits (356), Expect = 1e-33
Identities = 74/204 (36%), Positives = 126/204 (61%), Gaps = 4/204 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L++R+ LV ++ +K + I++++ML + +REY + FPEI+ RA+ L++ FG++L+
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID + Y LV R + ++ D P+ SLL ++LG I +NGNRA EA +W+ L K+
Sbjct: 473 IDKEEHLYILVCTRDSSAR-LLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P + G+ R L+T DFV ++LEY + +NP E+EFLWG RA E +KM
Sbjct: 532 GL--RPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRV 589
Query: 267 LKFVSDAHDEEPWSWPEEYNKALE 290
L+F++ + +P W + +A++
Sbjct: 590 LRFIAQNQNRDPREWKAHFLEAVD 613
Score = 138 bits (347), Expect = 1e-32
Identities = 72/203 (35%), Positives = 120/203 (59%), Gaps = 9/203 (4%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + + +PI + ++L +E+++ FP I+ RAT L+ +G+ L E
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D EH+Y+LV +S +++ ++ P ++ ILG+IF+ GNR EA +W LR+
Sbjct: 473 IDKEEHLYILVCTRDSSA-RLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H IT ++Q+YLE + + SNP EYE LWG RA HET KM+VL
Sbjct: 532 GLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLR 591
Query: 483 YMARLYRKRPQNWPEQYREAVED 505
++A+ + P+ W + EAV+D
Sbjct: 592 FIAQNQNRDPREWKAHFLEAVDD 614
>gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
Length = 741
Score = 141 bits (356), Expect = 1e-33
Identities = 74/204 (36%), Positives = 126/204 (61%), Gaps = 4/204 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L++R+ LV ++ +K + I++++ML + +REY + FPEI+ RA+ L++ FG++L+
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID + Y LV R + ++ D P+ SLL ++LG I +NGNRA EA +W+ L K+
Sbjct: 473 IDKEEHLYILVCTRDSSAR-LLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P + G+ R L+T DFV ++LEY + +NP E+EFLWG RA E +KM
Sbjct: 532 GL--RPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRV 589
Query: 267 LKFVSDAHDEEPWSWPEEYNKALE 290
L+F++ + +P W + +A++
Sbjct: 590 LRFIAQNQNRDPREWKAHFLEAVD 613
Score = 138 bits (347), Expect = 1e-32
Identities = 72/203 (35%), Positives = 120/203 (59%), Gaps = 9/203 (4%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + + +PI + ++L +E+++ FP I+ RAT L+ +G+ L E
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D EH+Y+LV +S +++ ++ P ++ ILG+IF+ GNR EA +W LR+
Sbjct: 473 IDKEEHLYILVCTRDSSA-RLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H IT ++Q+YLE + + SNP EYE LWG RA HET KM+VL
Sbjct: 532 GLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLR 591
Query: 483 YMARLYRKRPQNWPEQYREAVED 505
++A+ + P+ W + EAV+D
Sbjct: 592 FIAQNQNRDPREWKAHFLEAVDD 614
>gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
Length = 741
Score = 141 bits (356), Expect = 1e-33
Identities = 74/204 (36%), Positives = 126/204 (61%), Gaps = 4/204 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L++R+ LV ++ +K + I++++ML + +REY + FPEI+ RA+ L++ FG++L+
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID + Y LV R + ++ D P+ SLL ++LG I +NGNRA EA +W+ L K+
Sbjct: 473 IDKEEHLYILVCTRDSSAR-LLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P + G+ R L+T DFV ++LEY + +NP E+EFLWG RA E +KM
Sbjct: 532 GL--RPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRV 589
Query: 267 LKFVSDAHDEEPWSWPEEYNKALE 290
L+F++ + +P W + +A++
Sbjct: 590 LRFIAQNQNRDPREWKAHFLEAVD 613
Score = 138 bits (347), Expect = 1e-32
Identities = 72/203 (35%), Positives = 120/203 (59%), Gaps = 9/203 (4%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + + +PI + ++L +E+++ FP I+ RAT L+ +G+ L E
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D EH+Y+LV +S +++ ++ P ++ ILG+IF+ GNR EA +W LR+
Sbjct: 473 IDKEEHLYILVCTRDSSA-RLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H IT ++Q+YLE + + SNP EYE LWG RA HET KM+VL
Sbjct: 532 GLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLR 591
Query: 483 YMARLYRKRPQNWPEQYREAVED 505
++A+ + P+ W + EAV+D
Sbjct: 592 FIAQNQNRDPREWKAHFLEAVDD 614
>gi|149274614 melanoma antigen family D, 4 [Homo sapiens]
Length = 739
Score = 141 bits (356), Expect = 1e-33
Identities = 74/204 (36%), Positives = 126/204 (61%), Gaps = 4/204 (1%)
Query: 88 LEDRSIALVNFMRMKSQTEGSIQQSEML-EFLREYSDQFPEILRRASAHLDQVFGLNLRV 146
L++R+ LV ++ +K + I++++ML + +REY + FPEI+ RA+ L++ FG++L+
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 147 IDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKV 206
ID + Y LV R + ++ D P+ SLL ++LG I +NGNRA EA +W+ L K+
Sbjct: 473 IDKEEHLYILVCTRDSSAR-LLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 207 DMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEA 266
+ +P + G+ R L+T DFV ++LEY + +NP E+EFLWG RA E +KM
Sbjct: 532 GL--RPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRV 589
Query: 267 LKFVSDAHDEEPWSWPEEYNKALE 290
L+F++ + +P W + +A++
Sbjct: 590 LRFIAQNQNRDPREWKAHFLEAVD 613
Score = 138 bits (347), Expect = 1e-32
Identities = 72/203 (35%), Positives = 120/203 (59%), Gaps = 9/203 (4%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+ ++AN LV+ + + +PI + ++L +E+++ FP I+ RAT L+ +G+ L E
Sbjct: 413 LQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKE 472
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
+D EH+Y+LV +S +++ ++ P ++ ILG+IF+ GNR EA +W LR+
Sbjct: 473 IDKEEHLYILVCTRDSSA-RLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKM 531
Query: 431 SVDVGRKHS--------ITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H IT ++Q+YLE + + SNP EYE LWG RA HET KM+VL
Sbjct: 532 GLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLR 591
Query: 483 YMARLYRKRPQNWPEQYREAVED 505
++A+ + P+ W + EAV+D
Sbjct: 592 FIAQNQNRDPREWKAHFLEAVDD 614
>gi|73623441 melanoma antigen family B, 10 [Homo sapiens]
Length = 347
Score = 140 bits (353), Expect = 3e-33
Identities = 75/216 (34%), Positives = 125/216 (57%), Gaps = 3/216 (1%)
Query: 87 PLEDRSIALVNFMRMKSQTEGSIQQSEMLEFLREYS-DQFPEILRRASAHLDQVFGLNLR 145
P++++ I LV+++ K Q + I +++ML + + S QFP IL RAS HL+ +FGL+L+
Sbjct: 110 PVDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLK 169
Query: 146 VIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLK 205
++P Y LV+K ++++ +PK LL VLG I NGN E +W +
Sbjct: 170 EVEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNT 229
Query: 206 VDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKME 265
+ ++D + +FG R LLT D V +LEY V ++P ++FLWG RAH E +KM+
Sbjct: 230 MGLYDGIEHF--MFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMK 287
Query: 266 ALKFVSDAHDEEPWSWPEEYNKALEGDKTKERSLTA 301
L+F++ +D P + Y +AL+ ++ + R+ A
Sbjct: 288 VLEFLAKVNDTAPSEFSNWYTEALQDEEERARARVA 323
Score = 129 bits (323), Expect = 9e-30
Identities = 78/239 (32%), Positives = 129/239 (53%), Gaps = 9/239 (3%)
Query: 282 PEEYNKALEGDKTKERSLTAGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHT 341
PE N +E + L A F +++K LV + + PI + ++L +
Sbjct: 83 PEGVNDQMEERPICTQDLEATDSF-PRGPVDEKVIILVHYLLYKYQMKEPITKADMLRNV 141
Query: 342 GKEFEDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQ 401
+ + FP IL+RA+ L++ +GL L EV+ ++HIY+LV + + + + + G P
Sbjct: 142 TQMSKSQFPVILSRASEHLELIFGLDLKEVEPNKHIYVLVNKLDLGCDAKLSDETGVPKT 201
Query: 402 EYVMPILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHS--------ITRKLMRQRYLECR 453
+M +LG+IF GN V E VW + + G +H +T+ L+++ YLE +
Sbjct: 202 GLLMTVLGIIFTNGNCVAEEEVWKVFNTMGLYDGIEHFMFGEPRKLLTKDLVKENYLEYQ 261
Query: 454 PLSYSNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREAVEDEEARAKS 512
+ S+P Y+ LWGPRAH ET KMKVLE++A++ P + Y EA++DEE RA++
Sbjct: 262 QVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDTAPSEFSNWYTEALQDEEERARA 320
>gi|58530863 melanoma antigen family A, 10 [Homo sapiens]
Length = 369
Score = 139 bits (349), Expect = 8e-33
Identities = 87/289 (30%), Positives = 150/289 (51%), Gaps = 16/289 (5%)
Query: 14 EITADYGDGRGEIQATNASGSPTSMLVVDAPQCPQAPINSQCVNTSQAVQDPNDLEVLID 73
E++AD A A SP+ + + Q + ++SQ + P+ L+VL D
Sbjct: 73 EVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEG-------SSSQKEESPSTLQVLPD 125
Query: 74 EQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEMLE-FLREYSDQFPEILRRA 132
+S ++++ LV F+ K Q + I ++E+LE ++ Y D FP + A
Sbjct: 126 SESLP------RSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEA 179
Query: 133 SAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGN 192
S + VFG++++ +DP ++ LV+ G +++ MPK +L L+L I + G
Sbjct: 180 SECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGY 239
Query: 193 RAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFL 252
E IW+ L + ++D + + ++G R LLT D+V +LEY V G++P +EFL
Sbjct: 240 CTPEEVIWEALNMMGLYDGMEHL--IYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFL 297
Query: 253 WGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALEGDKTKERSLTA 301
WG RAH EI KM LKF++ + +P S+P Y +AL+ ++ + + A
Sbjct: 298 WGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIA 346
Score = 114 bits (286), Expect = 2e-25
Identities = 68/209 (32%), Positives = 113/209 (54%), Gaps = 8/209 (3%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+++K DLVQ + + PI + E+L K +ED FP + + A+ + + +G+ + E
Sbjct: 134 IDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKE 193
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
VD + H ++LV + ++ + P ++ IL +IF+ G E +W L
Sbjct: 194 VDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEALNMM 253
Query: 431 SVDVGRKHSI---TRKLMRQ-----RYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H I RKL+ Q YLE R + S+P YE LWGPRAH E KM +L+
Sbjct: 254 GLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLK 313
Query: 483 YMARLYRKRPQNWPEQYREAVEDEEARAK 511
++A++ P+++P Y EA++DEE RA+
Sbjct: 314 FLAKVNGSDPRSFPLWYEEALKDEEERAQ 342
>gi|10567820 melanoma antigen family A, 10 [Homo sapiens]
Length = 369
Score = 139 bits (349), Expect = 8e-33
Identities = 87/289 (30%), Positives = 150/289 (51%), Gaps = 16/289 (5%)
Query: 14 EITADYGDGRGEIQATNASGSPTSMLVVDAPQCPQAPINSQCVNTSQAVQDPNDLEVLID 73
E++AD A A SP+ + + Q + ++SQ + P+ L+VL D
Sbjct: 73 EVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEG-------SSSQKEESPSTLQVLPD 125
Query: 74 EQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEMLE-FLREYSDQFPEILRRA 132
+S ++++ LV F+ K Q + I ++E+LE ++ Y D FP + A
Sbjct: 126 SESLP------RSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEA 179
Query: 133 SAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGN 192
S + VFG++++ +DP ++ LV+ G +++ MPK +L L+L I + G
Sbjct: 180 SECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGY 239
Query: 193 RAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFL 252
E IW+ L + ++D + + ++G R LLT D+V +LEY V G++P +EFL
Sbjct: 240 CTPEEVIWEALNMMGLYDGMEHL--IYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFL 297
Query: 253 WGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALEGDKTKERSLTA 301
WG RAH EI KM LKF++ + +P S+P Y +AL+ ++ + + A
Sbjct: 298 WGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIA 346
Score = 114 bits (286), Expect = 2e-25
Identities = 68/209 (32%), Positives = 113/209 (54%), Gaps = 8/209 (3%)
Query: 311 MNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIE 370
+++K DLVQ + + PI + E+L K +ED FP + + A+ + + +G+ + E
Sbjct: 134 IDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKE 193
Query: 371 VDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRF 430
VD + H ++LV + ++ + P ++ IL +IF+ G E +W L
Sbjct: 194 VDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEALNMM 253
Query: 431 SVDVGRKHSI---TRKLMRQ-----RYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLE 482
+ G +H I RKL+ Q YLE R + S+P YE LWGPRAH E KM +L+
Sbjct: 254 GLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLK 313
Query: 483 YMARLYRKRPQNWPEQYREAVEDEEARAK 511
++A++ P+++P Y EA++DEE RA+
Sbjct: 314 FLAKVNGSDPRSFPLWYEEALKDEEERAQ 342
>gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens]
Length = 400
Score = 138 bits (347), Expect = 1e-32
Identities = 82/232 (35%), Positives = 131/232 (56%), Gaps = 9/232 (3%)
Query: 59 SQAVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEML-EF 117
SQ + P+ LID +S D L D+ I LV+ + K + +G I ++EML
Sbjct: 170 SQEKEGPSTSPDLIDPESFS------QDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSV 223
Query: 118 LREYSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKA 177
++ Y D FPEI R AS + +FG++++ +DP + +Y LV+ MPK+
Sbjct: 224 IKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKS 283
Query: 178 SLLALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLE 237
LL +VLG I + GN E +W++L + ++ R + LFG + LLT ++V ++L
Sbjct: 284 GLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVY--AGREHFLFGEPKRLLTQNWVQEKYLV 341
Query: 238 YWPVYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKAL 289
Y V GT+P +EFLWG RAH E +KM+ L+++++A+ +P S+P Y AL
Sbjct: 342 YRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDAL 393
Score = 130 bits (326), Expect = 4e-30
Identities = 70/211 (33%), Positives = 114/211 (54%), Gaps = 8/211 (3%)
Query: 304 EFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMF 363
E +S+D ++DK DLV L + I + E+L K +ED FP I A++ + +
Sbjct: 186 ESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFREASVCMQLL 245
Query: 364 YGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANV 423
+G+ + EVD + H Y+LV + + P ++ +LG+IF+ GN + E +
Sbjct: 246 FGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVM 305
Query: 424 WNLLRRFSVDVGRKH--------SITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHET 475
W +L V GR+H +T+ ++++YL R + ++P YE LWGPRAH ET
Sbjct: 306 WEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYEFLWGPRAHAET 365
Query: 476 IKMKVLEYMARLYRKRPQNWPEQYREAVEDE 506
KMKVLEY+A + P ++P Y +A+ +E
Sbjct: 366 SKMKVLEYIANANGRDPTSYPSLYEDALREE 396
>gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens]
Length = 429
Score = 138 bits (347), Expect = 1e-32
Identities = 82/232 (35%), Positives = 131/232 (56%), Gaps = 9/232 (3%)
Query: 59 SQAVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEML-EF 117
SQ + P+ LID +S D L D+ I LV+ + K + +G I ++EML
Sbjct: 199 SQEKEGPSTSPDLIDPESFS------QDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSV 252
Query: 118 LREYSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKA 177
++ Y D FPEI R AS + +FG++++ +DP + +Y LV+ MPK+
Sbjct: 253 IKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKS 312
Query: 178 SLLALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLE 237
LL +VLG I + GN E +W++L + ++ R + LFG + LLT ++V ++L
Sbjct: 313 GLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVY--AGREHFLFGEPKRLLTQNWVQEKYLV 370
Query: 238 YWPVYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKAL 289
Y V GT+P +EFLWG RAH E +KM+ L+++++A+ +P S+P Y AL
Sbjct: 371 YRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDAL 422
Score = 130 bits (326), Expect = 4e-30
Identities = 70/211 (33%), Positives = 114/211 (54%), Gaps = 8/211 (3%)
Query: 304 EFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMF 363
E +S+D ++DK DLV L + I + E+L K +ED FP I A++ + +
Sbjct: 215 ESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFREASVCMQLL 274
Query: 364 YGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANV 423
+G+ + EVD + H Y+LV + + P ++ +LG+IF+ GN + E +
Sbjct: 275 FGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVM 334
Query: 424 WNLLRRFSVDVGRKH--------SITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHET 475
W +L V GR+H +T+ ++++YL R + ++P YE LWGPRAH ET
Sbjct: 335 WEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYEFLWGPRAHAET 394
Query: 476 IKMKVLEYMARLYRKRPQNWPEQYREAVEDE 506
KMKVLEY+A + P ++P Y +A+ +E
Sbjct: 395 SKMKVLEYIANANGRDPTSYPSLYEDALREE 425
>gi|29171714 melanoma antigen family B, 3 [Homo sapiens]
Length = 346
Score = 137 bits (346), Expect = 2e-32
Identities = 80/246 (32%), Positives = 134/246 (54%), Gaps = 14/246 (5%)
Query: 285 YNKALEGDKTK---ERSLTAGLEFWSE---DTMNDKANDLVQLAISVTEEMLPIHQDELL 338
Y K+ +G +K ++S + GL + D + K N LVQ + + + PI + ++L
Sbjct: 79 YKKSYKGANSKIEKKQSFSQGLSSTVQSRTDPLIMKTNMLVQFLMEMYKMKKPIMKADML 138
Query: 339 AHTGKEFEDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGR 398
K ++ FP IL +A+ +++ +G+ L +VD+++ Y+LV + + + G
Sbjct: 139 KIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYVLVSKMDLPNNGTVTRGRGF 198
Query: 399 PTQEYVMPILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHSI--------TRKLMRQRYL 450
P ++ +LG+IF+ GN E +W L + + G+KH I T+ L++ +YL
Sbjct: 199 PKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHFIFGEPRKLITQDLVKLKYL 258
Query: 451 ECRPLSYSNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREAVEDEEARA 510
E R + SNP YE LWGPRAH ET KMKVLE+ A++ + P + Y EA+ DEE R
Sbjct: 259 EYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTVPSAFQFWYEEALRDEEERV 318
Query: 511 KSEATI 516
++ A +
Sbjct: 319 QAAAML 324
Score = 132 bits (333), Expect = 6e-31
Identities = 73/211 (34%), Positives = 123/211 (58%), Gaps = 3/211 (1%)
Query: 86 DPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFLRE-YSDQFPEILRRASAHLDQVFGLNL 144
DPL ++ LV F+ + + I +++ML+ +++ + + FPEIL++AS +++ VFG++L
Sbjct: 109 DPLIMKTNMLVQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDL 168
Query: 145 RVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLL 204
+ +D D+Y LVSK + PK LL +LG I + GN A E IW+ L
Sbjct: 169 KKVDSTKDSYVLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLN 228
Query: 205 KVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKM 264
K+ ++D + +FG R L+T D V +++LEY V +NP +EFLWG RAH E +KM
Sbjct: 229 KMRIYDGKKHF--IFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKM 286
Query: 265 EALKFVSDAHDEEPWSWPEEYNKALEGDKTK 295
+ L+F + + P ++ Y +AL ++ +
Sbjct: 287 KVLEFWAKVNKTVPSAFQFWYEEALRDEEER 317
>gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo
sapiens]
Length = 457
Score = 133 bits (334), Expect = 5e-31
Identities = 78/240 (32%), Positives = 126/240 (52%), Gaps = 8/240 (3%)
Query: 283 EEYNKALEGDKTKERSLTAGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTG 342
+E K +G+ + E D +N K +LVQ ++ PI ++ +L
Sbjct: 202 DEGAKGQKGESPNSFHGPSSSESTGRDLLNTKTGELVQFLLNKYIRKEPITREAMLKVIN 261
Query: 343 KEFEDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQE 402
++++ FP IL R+T +++ +GL L E+D S Y+LV + + + + + G P
Sbjct: 262 RKYKQHFPEILRRSTENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSG 321
Query: 403 YVMPILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHSI--------TRKLMRQRYLECRP 454
+M +L IF+ GNR E +W L + GRKH I T+ L+R+ YLE +
Sbjct: 322 LLMVLLSTIFMHGNRATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQ 381
Query: 455 LSYSNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREAVEDEEARAKSEA 514
+ S+P YE LWGPRA ET KMKVLE++A+L + +Y EA+ +EE +A++ A
Sbjct: 382 VPSSDPPRYEFLWGPRARAETSKMKVLEFVAKLNDTVASTYKSRYEEALREEEEQARARA 441
Score = 124 bits (310), Expect = 3e-28
Identities = 72/214 (33%), Positives = 121/214 (56%), Gaps = 3/214 (1%)
Query: 86 DPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFL-REYSDQFPEILRRASAHLDQVFGLNL 144
D L ++ LV F+ K + I + ML+ + R+Y FPEILRR++ +++ VFGL L
Sbjct: 228 DLLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYL 287
Query: 145 RVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLL 204
+ +DP +Y LV K F +++ P + LL ++L I ++GNRA E +W+ L
Sbjct: 288 KEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLN 347
Query: 205 KVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKM 264
+ M+ R + ++G + L+T D V +LEY V ++P +EFLWG RA E +KM
Sbjct: 348 ALGMY--KGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKM 405
Query: 265 EALKFVSDAHDEEPWSWPEEYNKALEGDKTKERS 298
+ L+FV+ +D ++ Y +AL ++ + R+
Sbjct: 406 KVLEFVAKLNDTVASTYKSRYEEALREEEEQARA 439
>gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo
sapiens]
Length = 457
Score = 133 bits (334), Expect = 5e-31
Identities = 78/240 (32%), Positives = 126/240 (52%), Gaps = 8/240 (3%)
Query: 283 EEYNKALEGDKTKERSLTAGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTG 342
+E K +G+ + E D +N K +LVQ ++ PI ++ +L
Sbjct: 202 DEGAKGQKGESPNSFHGPSSSESTGRDLLNTKTGELVQFLLNKYIRKEPITREAMLKVIN 261
Query: 343 KEFEDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQE 402
++++ FP IL R+T +++ +GL L E+D S Y+LV + + + + + G P
Sbjct: 262 RKYKQHFPEILRRSTENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSG 321
Query: 403 YVMPILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHSI--------TRKLMRQRYLECRP 454
+M +L IF+ GNR E +W L + GRKH I T+ L+R+ YLE +
Sbjct: 322 LLMVLLSTIFMHGNRATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQ 381
Query: 455 LSYSNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREAVEDEEARAKSEA 514
+ S+P YE LWGPRA ET KMKVLE++A+L + +Y EA+ +EE +A++ A
Sbjct: 382 VPSSDPPRYEFLWGPRARAETSKMKVLEFVAKLNDTVASTYKSRYEEALREEEEQARARA 441
Score = 124 bits (310), Expect = 3e-28
Identities = 72/214 (33%), Positives = 121/214 (56%), Gaps = 3/214 (1%)
Query: 86 DPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFL-REYSDQFPEILRRASAHLDQVFGLNL 144
D L ++ LV F+ K + I + ML+ + R+Y FPEILRR++ +++ VFGL L
Sbjct: 228 DLLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYL 287
Query: 145 RVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLL 204
+ +DP +Y LV K F +++ P + LL ++L I ++GNRA E +W+ L
Sbjct: 288 KEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLN 347
Query: 205 KVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKM 264
+ M+ R + ++G + L+T D V +LEY V ++P +EFLWG RA E +KM
Sbjct: 348 ALGMY--KGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKM 405
Query: 265 EALKFVSDAHDEEPWSWPEEYNKALEGDKTKERS 298
+ L+FV+ +D ++ Y +AL ++ + R+
Sbjct: 406 KVLEFVAKLNDTVASTYKSRYEEALREEEEQARA 439
>gi|169216802 PREDICTED: melanoma antigen family B, 17 [Homo
sapiens]
Length = 457
Score = 133 bits (334), Expect = 5e-31
Identities = 78/240 (32%), Positives = 126/240 (52%), Gaps = 8/240 (3%)
Query: 283 EEYNKALEGDKTKERSLTAGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTG 342
+E K +G+ + E D +N K +LVQ ++ PI ++ +L
Sbjct: 202 DEGAKGQKGESPNSFHGPSSSESTGRDLLNTKTGELVQFLLNKYIRKEPITREAMLKVIN 261
Query: 343 KEFEDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQE 402
++++ FP IL R+T +++ +GL L E+D S Y+LV + + + + + G P
Sbjct: 262 RKYKQHFPEILRRSTENVEVVFGLYLKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSG 321
Query: 403 YVMPILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHSI--------TRKLMRQRYLECRP 454
+M +L IF+ GNR E +W L + GRKH I T+ L+R+ YLE +
Sbjct: 322 LLMVLLSTIFMHGNRATEEEMWECLNALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQ 381
Query: 455 LSYSNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREAVEDEEARAKSEA 514
+ S+P YE LWGPRA ET KMKVLE++A+L + +Y EA+ +EE +A++ A
Sbjct: 382 VPSSDPPRYEFLWGPRARAETSKMKVLEFVAKLNDTVASTYKSRYEEALREEEEQARARA 441
Score = 124 bits (310), Expect = 3e-28
Identities = 72/214 (33%), Positives = 121/214 (56%), Gaps = 3/214 (1%)
Query: 86 DPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFL-REYSDQFPEILRRASAHLDQVFGLNL 144
D L ++ LV F+ K + I + ML+ + R+Y FPEILRR++ +++ VFGL L
Sbjct: 228 DLLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYL 287
Query: 145 RVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLL 204
+ +DP +Y LV K F +++ P + LL ++L I ++GNRA E +W+ L
Sbjct: 288 KEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLN 347
Query: 205 KVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKM 264
+ M+ R + ++G + L+T D V +LEY V ++P +EFLWG RA E +KM
Sbjct: 348 ALGMY--KGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKM 405
Query: 265 EALKFVSDAHDEEPWSWPEEYNKALEGDKTKERS 298
+ L+FV+ +D ++ Y +AL ++ + R+
Sbjct: 406 KVLEFVAKLNDTVASTYKSRYEEALREEEEQARA 439
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,581,281
Number of Sequences: 37866
Number of extensions: 801939
Number of successful extensions: 2408
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2049
Number of HSP's gapped (non-prelim): 154
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.