Guide to the Human Genome
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Search of human proteins with 20149629

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
         (455 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   891   0.0  
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   769   0.0  
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   369   e-102
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   271   9e-73
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   253   2e-67
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...   231   8e-61
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   230   2e-60
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            224   1e-58
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            224   1e-58
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         222   5e-58
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   222   5e-58
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi...   222   5e-58
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          221   8e-58
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   215   8e-56
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   214   1e-55
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    214   2e-55
gi|4758112 HLA-B associated transcript 1 [Homo sapiens]               211   8e-55
gi|18375623 HLA-B associated transcript 1 [Homo sapiens]              211   8e-55
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   210   2e-54
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   210   2e-54
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   210   2e-54
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   209   3e-54
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   209   3e-54
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   207   2e-53
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  206   5e-53
gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]   205   8e-53
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   204   1e-52
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   203   3e-52
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   202   5e-52
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi...   201   9e-52

>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  891 bits (2302), Expect = 0.0
 Identities = 455/455 (100%), Positives = 455/455 (100%)

Query: 1   MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
           MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
Sbjct: 1   MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60

Query: 61  GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
           GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
Sbjct: 61  GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120

Query: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
           VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
Sbjct: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180

Query: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
           NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
Sbjct: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240

Query: 241 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
           YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS
Sbjct: 241 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300

Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
           KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
Sbjct: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360

Query: 361 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 420
           GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
Sbjct: 361 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 420

Query: 421 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 455
           KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
Sbjct: 421 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 455


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  769 bits (1986), Expect = 0.0
 Identities = 406/455 (89%), Positives = 406/455 (89%), Gaps = 49/455 (10%)

Query: 1   MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
           MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
Sbjct: 1   MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60

Query: 61  GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
           GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
Sbjct: 61  GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120

Query: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
           VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
Sbjct: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180

Query: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
           NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
Sbjct: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240

Query: 241 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
           YYIFIPSKFK                                                 S
Sbjct: 241 YYIFIPSKFK-------------------------------------------------S 251

Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
           KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
Sbjct: 252 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 311

Query: 361 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 420
           GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
Sbjct: 312 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 371

Query: 421 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 455
           KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
Sbjct: 372 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 406


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  369 bits (947), Expect = e-102
 Identities = 195/439 (44%), Positives = 275/439 (62%), Gaps = 9/439 (2%)

Query: 26  FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
           F +LG++  L E C QLG  +PT +Q+  IP  L+GRD +G A+TGSGKT AF LPIL  
Sbjct: 4   FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63

Query: 86  LLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHI 145
           L E P  +F LVLTPTRELA+QI+EQF  LG  +G++  +IVGG+D ++Q+L L++KPH+
Sbjct: 64  LSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHV 123

Query: 146 IIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNM---DFETEVDKILKVIPRDRKTF 202
           +IATPGRL DHL ++  F+++ +++LVMDEADR+L     DF  +++ IL  +P  R+T 
Sbjct: 124 VIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTL 183

Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELA 262
           LFSAT+T  +++LQ  A   P      +   TVE+L Q Y+ +P K KD YLV+++    
Sbjct: 184 LFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQ 243

Query: 263 GN----SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILL 318
                 S +IF +TC   Q   ++LR   F  + LH  M Q +R  +L KFK+    IL+
Sbjct: 244 DEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILI 303

Query: 319 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 378
           ATDVASRGLDIP V VV+N + P   K YIHRVGRTARAGR G+AIT VTQYD+ L   I
Sbjct: 304 ATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAI 363

Query: 379 EHLIGKKLPGFPTQDDEVMMLTERVAEAQRFA--RMELREHGEKKKRSREDAGDNDDTEG 436
           E  I KKL  F  ++ EV+ +  +V   +R    ++E     EKK+ ++      +  + 
Sbjct: 364 EEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDP 423

Query: 437 AIGVRNKVAGGKMKKRKGR 455
            +  + K    K+K++  R
Sbjct: 424 DLEAKRKAELAKIKQKNRR 442


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  271 bits (693), Expect = 9e-73
 Identities = 154/417 (36%), Positives = 244/417 (58%), Gaps = 6/417 (1%)

Query: 21  EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80
           +E  +F+D+ ++  L +A   +G+ +PT IQ   IP+ L G+DI   A TG+GKT AFAL
Sbjct: 215 DENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFAL 274

Query: 81  PILNALLETPQRL---FALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSL 137
           P+L  L+  P++      LVL PTREL  Q+      L     + + + VGG+D  SQ  
Sbjct: 275 PVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEA 334

Query: 138 ALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPR 197
           AL   P I+IATPGRLIDHL N   F+L +++ L++DEADR+L+  FE ++ +I+++   
Sbjct: 335 ALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSH 394

Query: 198 DRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI-PSK--FKDTYL 254
            R+T LFSATMT +V+ L   +LKNPV+  V+S       L+Q +I I P++   ++  +
Sbjct: 395 HRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIV 454

Query: 255 VYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKAR 314
             +L     +  M+F  T     R  +LL  +G     LHG +SQ++RL +L +FK +  
Sbjct: 455 AALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQI 514

Query: 315 SILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVEL 374
            IL+ATDVA+RGLDI  V  V+NF +P   K Y+HRVGRTARAGR+G++++ V + + ++
Sbjct: 515 DILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKM 574

Query: 375 FQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDN 431
            + I       +       D ++   +++ + ++     L+   E+K+  + +A  N
Sbjct: 575 LKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQIN 631


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  253 bits (647), Expect = 2e-67
 Identities = 150/394 (38%), Positives = 224/394 (56%), Gaps = 36/394 (9%)

Query: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
           +++KD  +   + E  D+ G+ +PT IQ +AIP+ LQ RDIIG+AETGSGKT AF +P+L
Sbjct: 391 RSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLL 450

Query: 84  ---------NALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
                    + + E+ Q  +A++L PTRELA QI E+    G  +G+++  ++GGI    
Sbjct: 451 VWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISRED 510

Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
           Q   L     I+IATPGRLID LEN +   L    Y+V+DEADR+++M FE +V KIL+ 
Sbjct: 511 QGFRLRMGCEIVIATPGRLIDVLEN-RYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEH 569

Query: 195 IP--------------------------RDRKTFLFSATMTKKVQKLQRAALKNPVKCAV 228
           +P                          + R+T +F+ATM   V++L R+ L+ P    +
Sbjct: 570 MPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYI 629

Query: 229 SSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGF 288
            S  +  E+++Q    +    K   L+ IL +      +IF +        A  L  +G+
Sbjct: 630 GSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGY 689

Query: 289 TAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYI 348
            A  LHG   Q +R  +L+  KA A+ IL+ATDVA RG+DI  V +VVN+D+  + +DYI
Sbjct: 690 NACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYI 749

Query: 349 HRVGRTARAGRSGKAITFVTQYDVELFQRIEHLI 382
           HR+GRT RAG+SG AITF+T+ D  +F  ++  I
Sbjct: 750 HRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAI 783


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score =  231 bits (590), Expect = 8e-61
 Identities = 141/416 (33%), Positives = 229/416 (55%), Gaps = 17/416 (4%)

Query: 18  VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77
           +   E   F D  ++    +   +  +   T+IQ + I LALQG+D++G A+TGSGKT A
Sbjct: 63  INVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLA 122

Query: 78  FALPILNALLE----TPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSM 133
           F +P+L AL      +   L  L+++PTRELA+Q  E    +G +    + +I+GG D  
Sbjct: 123 FLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182

Query: 134 SQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILK 193
            ++  +    +I++ TPGRL+ H++ T  F+   L+ LV+DEADRIL+M F   ++ +++
Sbjct: 183 HEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241

Query: 194 VIPRDRKTFLFSATMTKKVQKLQRAALKNP--VKCAVSSKYQTVEKLQQYYIFIPSKFKD 251
            +P+ R+T LFSAT TK V+ L R +LKNP  V     +KY T   L+Q YI    + K 
Sbjct: 242 NLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKI 301

Query: 252 TYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNL--GFTAIPLHGQMSQSKRLGSLNKF 309
           + L   L        ++F S+C   Q    +   L  G + + LHG+  Q +R+   N+F
Sbjct: 302 SVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEF 361

Query: 310 KAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 369
             K  ++L ATD+A+RGLD P V+ V+ FD P  +  YIHR GRTAR    G+A+  +  
Sbjct: 362 VRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLP 421

Query: 370 YDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSR 425
            +  +   ++ L+ KK+P       E+ +  E++ + Q+     L +  + K+R++
Sbjct: 422 SEKAM---VQQLLQKKVP-----VKEIKINPEKLIDVQKKLESILAQDQDLKERAQ 469


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  230 bits (587), Expect = 2e-60
 Identities = 146/447 (32%), Positives = 235/447 (52%), Gaps = 27/447 (6%)

Query: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
           K++   G++  +  +  + G+ KPT IQ +AIP  + GRD+IG+A+TGSGKT AF LP+ 
Sbjct: 372 KSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMF 431

Query: 84  NAL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLA 138
             +     LE  +   A+++TPTRELA QI+++ +    ++G++   + GG     Q   
Sbjct: 432 RHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAE 491

Query: 139 LAKKPHIIIATPGRLIDHLENTKG--FNLRALKYLVMDEADRILNMDFETEVDKILKVIP 196
           L +   II+ TPGR+ID L    G   NLR + Y+V+DEADR+ +M FE +V +I+  + 
Sbjct: 492 LKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVR 551

Query: 197 RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVY 256
            DR+T +FSAT  + ++ L R  L  P++  V  +      ++Q  I I  + K   L+ 
Sbjct: 552 PDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLE 611

Query: 257 ILNELA-GNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315
           +L       S +IF     +       L    +  + LHG + Q  R   +N FK     
Sbjct: 612 LLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCK 671

Query: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ----YD 371
           +L+AT VA+RGLD+ H+ +VVN+  P H +DY+HR GRT RAG  G A TF+T+    Y 
Sbjct: 672 LLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYA 731

Query: 372 VELFQRIEHLIGKKLP--------GFPTQDDEVMMLTERVA----EAQRFARMELREHGE 419
            ++ + +E L G  +P         F  Q      + ++ +    +  +F   E     E
Sbjct: 732 GDIIKALE-LSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANE 790

Query: 420 KKKRSREDAG--DNDDTEGAIGVRNKV 444
           +KK  +   G  D+DD + A+ +  ++
Sbjct: 791 RKKLQKAALGLQDSDDEDAAVDIDEQI 817


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  224 bits (571), Expect = 1e-58
 Identities = 136/356 (38%), Positives = 200/356 (56%), Gaps = 12/356 (3%)

Query: 25  TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84
           +F   G  + L     +  +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF  P+L 
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313

Query: 85  AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139
            +     LE      A+++ PTREL  QI  + +  G +  ++S  + GG     Q+ AL
Sbjct: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373

Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
            +   I++ TPGRLIDH++  K  NL+ + YLV DEADR+ +M FE +V  I   +  DR
Sbjct: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432

Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKFKDTYLVY 256
           +T LFSAT  KK++KL R  L +P++       +  E + Q    +   PSK+   +L  
Sbjct: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN--WLTR 490

Query: 257 ILNELAGN-SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315
            L E   + S ++F +   N +  A  L+  G     LHG M QS+R   ++ FK K   
Sbjct: 491 RLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIP 550

Query: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 371
           +L+ATDVA+RGLDIP +  V+N+D+      + HR+GRT RAG  G A T +T  D
Sbjct: 551 VLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  224 bits (571), Expect = 1e-58
 Identities = 136/356 (38%), Positives = 200/356 (56%), Gaps = 12/356 (3%)

Query: 25  TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84
           +F   G  + L     +  +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF  P+L 
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313

Query: 85  AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139
            +     LE      A+++ PTREL  QI  + +  G +  ++S  + GG     Q+ AL
Sbjct: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373

Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
            +   I++ TPGRLIDH++  K  NL+ + YLV DEADR+ +M FE +V  I   +  DR
Sbjct: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432

Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKFKDTYLVY 256
           +T LFSAT  KK++KL R  L +P++       +  E + Q    +   PSK+   +L  
Sbjct: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN--WLTR 490

Query: 257 ILNELAGN-SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315
            L E   + S ++F +   N +  A  L+  G     LHG M QS+R   ++ FK K   
Sbjct: 491 RLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIP 550

Query: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 371
           +L+ATDVA+RGLDIP +  V+N+D+      + HR+GRT RAG  G A T +T  D
Sbjct: 551 VLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  222 bits (566), Expect = 5e-58
 Identities = 150/397 (37%), Positives = 211/397 (53%), Gaps = 34/397 (8%)

Query: 44  WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
           +T+PT IQ +  PLAL GRD++G+A+TGSGKT A+ LP +        LE       LVL
Sbjct: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250

Query: 99  TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
            PTRELA Q+ +  +  G    ++S  I GG     Q   L +   I IATPGRLID LE
Sbjct: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310

Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
           + K  NLR   YLV+DEADR+L+M FE ++ KI+  I  DR+T ++SAT  K+V++L   
Sbjct: 311 SGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 369

Query: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274
            L++  +  V + +      + Q         KD  L+ ++ E+     N  +IF  T  
Sbjct: 370 FLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKR 429

Query: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334
                   +R  G+ A+ +HG  SQ +R   LN+F++    IL+ATDVASRGLD+  V  
Sbjct: 430 RCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKF 489

Query: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDD 394
           V+N+D P  S+DY+HR+GRTAR+   G A TF T                  PG   Q  
Sbjct: 490 VINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT------------------PGNLKQAR 531

Query: 395 EVMMLTERVAEAQRFARMELREH------GEKKKRSR 425
           E++ + E   +A     M+L +H      G K  RSR
Sbjct: 532 ELIKVLEEANQAINPKLMQLVDHRGGGGGGGKGGRSR 568


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  222 bits (566), Expect = 5e-58
 Identities = 125/395 (31%), Positives = 212/395 (53%), Gaps = 9/395 (2%)

Query: 5   EEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDI 64
           +E D      +   E + T TF  +G+ + L       G+ KP+ IQ  AI   ++GRD+
Sbjct: 19  KEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDV 78

Query: 65  IGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSA 124
           I  +++G+GKT  F++ +L  L    +   AL+L PTRELA QI +   ALG  + VQ  
Sbjct: 79  IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCH 138

Query: 125 VIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDF 184
             +GG +       L    H++  TPGR+ D +   +    RA+K LV+DEAD +LN  F
Sbjct: 139 ACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLNKGF 197

Query: 185 ETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIF 244
           + ++  + + +P   +  L SAT+  ++ ++    + +P++  V     T+E ++Q+++ 
Sbjct: 198 KEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257

Query: 245 IP-SKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRL 303
           +   ++K   L  + + L     +IFC+T          +R   FT   +HG M Q +R 
Sbjct: 258 VEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERE 317

Query: 304 GSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKA 363
             + +F++ A  +L++TDV +RGLD+P V +++N+D+P + + YIHR+GR+ R GR G A
Sbjct: 318 SIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA 377

Query: 364 ITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMM 398
           I FV   D+ + + IE         + TQ DE+ M
Sbjct: 378 INFVKNDDIRILRDIEQY-------YSTQIDEMPM 405


>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
           sapiens]
          Length = 670

 Score =  222 bits (566), Expect = 5e-58
 Identities = 134/339 (39%), Positives = 205/339 (60%), Gaps = 8/339 (2%)

Query: 31  VTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLET- 89
           V +   +A  ++G+T  T+IQ ++I   L+GRD++  A+TGSGKT AF +P +  +++  
Sbjct: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245

Query: 90  --PQR-LFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHII 146
             P+     L+L+PTRELA Q     + L +       +I+GG +  +++  L    +II
Sbjct: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINII 305

Query: 147 IATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSA 206
           +ATPGRL+DH++NT GF  + L+ LV+DEADRIL++ FE E+ +I+K++P  R+T LFSA
Sbjct: 306 VATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSA 365

Query: 207 TMTKKVQKLQRAAL-KNPVKCAV--SSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG 263
           T T+KV+ L R +L K P+   V       TV+ L+Q Y+  PS+ +   L   L +   
Sbjct: 366 TQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRK 425

Query: 264 NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVA 323
              M+F S+C + +    LL  +    + +HG+  Q+KR  +  +F       LL TDVA
Sbjct: 426 KKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVA 485

Query: 324 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGK 362
           +RGLDIP VD +V +D P   K+YIHRVGRTAR G +G+
Sbjct: 486 ARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGR 523


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  221 bits (564), Expect = 8e-58
 Identities = 145/383 (37%), Positives = 206/383 (53%), Gaps = 28/383 (7%)

Query: 44  WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
           +T+PT IQ +  PLAL GRD++G+A+TGSGKT A+ LP +        LE       LVL
Sbjct: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250

Query: 99  TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
            PTRELA Q+ +  +  G    ++S  I GG     Q   L +   I IATPGRLID LE
Sbjct: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310

Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
           + K  NLR   YLV+DEADR+L+M FE ++ KI+  I  DR+T ++SAT  K+V++L   
Sbjct: 311 SGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 369

Query: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274
            L++  +  V + +      + Q         KD  L+ ++ E+     N  +IF  T  
Sbjct: 370 FLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKR 429

Query: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334
                   +R  G+ A+ +HG  SQ +R   LN+F++    IL+ATDVASRGLD+  V  
Sbjct: 430 RCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKF 489

Query: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDD 394
           V+N+D P  S+DY+HR+GRTAR+   G A TF T                  PG   Q  
Sbjct: 490 VINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT------------------PGNLKQAR 531

Query: 395 EVMMLTERVAEAQRFARMELREH 417
           E++ + E   +A     M+L +H
Sbjct: 532 ELIKVLEEANQAINPKLMQLVDH 554


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  215 bits (547), Expect = 8e-56
 Identities = 123/382 (32%), Positives = 214/382 (56%), Gaps = 5/382 (1%)

Query: 26  FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
           F+D  +   L     ++GW KP+ IQ E+IP+AL GRDI+  A+ G+GK+GA+ +P+L  
Sbjct: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157

Query: 86  LLETPQRLFALVLTPTRELAFQISEQFEALGSSIG-VQSAVIVGGIDSMSQSLALAKKPH 144
           L      + A+V+ PTRELA Q+S+    +   +G  +     GG +     + L    H
Sbjct: 158 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217

Query: 145 IIIATPGRLIDHLENTKGF-NLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFL 203
           ++IATPGR++D ++  KG   +  ++ +V+DEAD++L+ DF   ++ I+  +P++R+  L
Sbjct: 218 VVIATPGRILDLIK--KGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILL 275

Query: 204 FSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG 263
           +SAT    VQK   + L+ P +  +  +  T++ + QYY ++  + K   L  + + L  
Sbjct: 276 YSATFPLSVQKFMNSHLQKPYEINLMEEL-TLKGVTQYYAYVTERQKVHCLNTLFSRLQI 334

Query: 264 NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVA 323
           N  +IFC++    +  A  +  LG++   +H +M Q  R    + F+      L+ TD+ 
Sbjct: 335 NQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLF 394

Query: 324 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIG 383
           +RG+DI  V+VV+NFD P  ++ Y+HR+GR+ R G  G AI  +T  D    + IE  +G
Sbjct: 395 TRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLG 454

Query: 384 KKLPGFPTQDDEVMMLTERVAE 405
            ++   P+  D+ + + E  +E
Sbjct: 455 TEIKPIPSNIDKSLYVAEYHSE 476


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  214 bits (545), Expect = 1e-55
 Identities = 131/382 (34%), Positives = 210/382 (54%), Gaps = 24/382 (6%)

Query: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
           ++F D+ + +++    +   +T+PT +Q  AIP+  + RD++  A+TGSGKT AF LPIL
Sbjct: 180 ESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPIL 239

Query: 84  NALLET------------------PQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
           + +                      Q   +LVL PTRELA QI E+         V+  V
Sbjct: 240 SQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 299

Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
           + GG D   Q   L +  H+++ATPGRL+D +E  K   L   KYLV+DEADR+L+M FE
Sbjct: 300 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 358

Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
            ++ +I++   + P+  R T +FSAT  K++Q L R  L   +  AV     T E + Q 
Sbjct: 359 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 418

Query: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
            +++    K ++L+ +LN    +S  ++F  T          L + G+    +HG  SQ 
Sbjct: 419 VVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 478

Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
            R  +L++F++    IL+AT VA+RGLDI +V  V+NFD+P+  ++Y+HR+GRT R G  
Sbjct: 479 DREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNL 538

Query: 361 GKAITFVTQYDVELFQRIEHLI 382
           G A +F  + ++ + + +  L+
Sbjct: 539 GLATSFFNERNINITKDLLDLL 560


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  214 bits (544), Expect = 2e-55
 Identities = 133/339 (39%), Positives = 192/339 (56%), Gaps = 10/339 (2%)

Query: 44  WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
           +T+PT IQ +  P+AL G D++G+A+TGSGKT ++ LP +        LE       LVL
Sbjct: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173

Query: 99  TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
            PTRELA Q+ +       +  ++S  I GG     Q   L +   I IATPGRLID LE
Sbjct: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233

Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
             K  NLR   YLV+DEADR+L+M FE ++ KI+  I  DR+T ++SAT  K+V++L   
Sbjct: 234 CGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 292

Query: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274
            LK+ +   + + +      + Q         KD  L+ ++ E+     N  ++F  T  
Sbjct: 293 FLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKR 352

Query: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334
                   +R  G+ A+ +HG  SQ +R   LN+FK     IL+ATDVASRGLD+  V  
Sbjct: 353 RCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKF 412

Query: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVE 373
           V+N+D P  S+DYIHR+GRTAR+ ++G A TF T  +++
Sbjct: 413 VINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK 451


>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  211 bits (538), Expect = 8e-55
 Identities = 125/374 (33%), Positives = 206/374 (55%), Gaps = 6/374 (1%)

Query: 26  FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
           F+D  +   L  A    G+  P+++Q E IP A+ G D++  A++G GKT  F L  L  
Sbjct: 47  FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106

Query: 86  LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
           L     ++  LV+  TRELAFQIS+++E     +  V+ AV  GG+        L K  P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166

Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILN-MDFETEVDKILKVIPRDRKTF 202
           HI++ TPGR++  L   K  NL+ +K+ ++DE D++L  +D   +V +I ++ P +++  
Sbjct: 167 HIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVM 225

Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKDTYLVYILNEL 261
           +FSAT++K+++ + R  +++P++  V  + + T+  LQQYY+ +    K+  L  +L+ L
Sbjct: 226 MFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVL 285

Query: 262 AGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATD 321
             N  +IF  +       A LL    F AI +H  M Q +RL    +FK   R IL+AT+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345

Query: 322 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 380
           +  RG+DI  V++  N+D+P  S  Y+HRV R  R G  G AITFV+ + D ++   ++ 
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405

Query: 381 LIGKKLPGFPTQDD 394
                +   P + D
Sbjct: 406 RFEVNISELPDEID 419


>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  211 bits (538), Expect = 8e-55
 Identities = 125/374 (33%), Positives = 206/374 (55%), Gaps = 6/374 (1%)

Query: 26  FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
           F+D  +   L  A    G+  P+++Q E IP A+ G D++  A++G GKT  F L  L  
Sbjct: 47  FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106

Query: 86  LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
           L     ++  LV+  TRELAFQIS+++E     +  V+ AV  GG+        L K  P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166

Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILN-MDFETEVDKILKVIPRDRKTF 202
           HI++ TPGR++  L   K  NL+ +K+ ++DE D++L  +D   +V +I ++ P +++  
Sbjct: 167 HIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVM 225

Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKDTYLVYILNEL 261
           +FSAT++K+++ + R  +++P++  V  + + T+  LQQYY+ +    K+  L  +L+ L
Sbjct: 226 MFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVL 285

Query: 262 AGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATD 321
             N  +IF  +       A LL    F AI +H  M Q +RL    +FK   R IL+AT+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345

Query: 322 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 380
           +  RG+DI  V++  N+D+P  S  Y+HRV R  R G  G AITFV+ + D ++   ++ 
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405

Query: 381 LIGKKLPGFPTQDD 394
                +   P + D
Sbjct: 406 RFEVNISELPDEID 419


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  210 bits (535), Expect = 2e-54
 Identities = 131/382 (34%), Positives = 207/382 (54%), Gaps = 24/382 (6%)

Query: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
           + F D+ + +++    +   +T+PT +Q  AIP+    RD++  A+TGSGKT AF LPIL
Sbjct: 178 ENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPIL 237

Query: 84  NALL------------------ETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
           + +                      Q   +LVL PTRELA QI E+         V+  V
Sbjct: 238 SQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 297

Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
           + GG D   Q   L +  H+++ATPGRL+D +E  K   L   KYLV+DEADR+L+M FE
Sbjct: 298 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 356

Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
            ++ +I++   + P+  R T +FSAT  K++Q L R  L   +  AV     T E + Q 
Sbjct: 357 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 416

Query: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
            +++    K ++L+ IL     +S  ++F  T          L + G+    +HG  SQ 
Sbjct: 417 VVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 476

Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
            R  +L++F++    IL+AT VA+RGLDI +V  V+NFD+P+  ++Y+HR+GRT R G  
Sbjct: 477 DREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL 536

Query: 361 GKAITFVTQYDVELFQRIEHLI 382
           G A +F  + ++ + + +  L+
Sbjct: 537 GLATSFFNEKNMNITKDLLDLL 558


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  210 bits (535), Expect = 2e-54
 Identities = 131/382 (34%), Positives = 207/382 (54%), Gaps = 24/382 (6%)

Query: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
           + F D+ + +++    +   +T+PT +Q  AIP+    RD++  A+TGSGKT AF LPIL
Sbjct: 178 ENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPIL 237

Query: 84  NALL------------------ETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
           + +                      Q   +LVL PTRELA QI E+         V+  V
Sbjct: 238 SQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 297

Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
           + GG D   Q   L +  H+++ATPGRL+D +E  K   L   KYLV+DEADR+L+M FE
Sbjct: 298 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 356

Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
            ++ +I++   + P+  R T +FSAT  K++Q L R  L   +  AV     T E + Q 
Sbjct: 357 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 416

Query: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
            +++    K ++L+ IL     +S  ++F  T          L + G+    +HG  SQ 
Sbjct: 417 VVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 476

Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
            R  +L++F++    IL+AT VA+RGLDI +V  V+NFD+P+  ++Y+HR+GRT R G  
Sbjct: 477 DREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL 536

Query: 361 GKAITFVTQYDVELFQRIEHLI 382
           G A +F  + ++ + + +  L+
Sbjct: 537 GLATSFFNEKNMNITKDLLDLL 558


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  210 bits (535), Expect = 2e-54
 Identities = 123/374 (32%), Positives = 209/374 (55%), Gaps = 6/374 (1%)

Query: 26  FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
           F+D  +   L  A    G+  P+++Q E IP A+ G D++  A++G GKT  F L  L  
Sbjct: 46  FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 105

Query: 86  LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
           +     ++  LV+  TRELAFQIS+++E     +  V+ +V  GG+        L K  P
Sbjct: 106 IEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCP 165

Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILN-MDFETEVDKILKVIPRDRKTF 202
           H+++ TPGR++  + N + F+L+ +K+ V+DE D++L  +D   +V +I ++ P +++  
Sbjct: 166 HVVVGTPGRILALVRN-RSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCM 224

Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKDTYLVYILNEL 261
           +FSAT++K ++ + R  +++P++  V  + + T+  LQQYY+ +    K+  L  +L+ L
Sbjct: 225 MFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVL 284

Query: 262 AGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATD 321
             N  +IF  +       A LL    F AI +H  M+Q +RL    +FK   R IL+AT+
Sbjct: 285 EFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATN 344

Query: 322 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 380
           +  RG+DI  V++V N+D+P  S  Y+HRV R  R G  G AITFV+ + D ++   ++ 
Sbjct: 345 LFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 404

Query: 381 LIGKKLPGFPTQDD 394
                +   P + D
Sbjct: 405 RFEVNVAELPEEID 418


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  209 bits (533), Expect = 3e-54
 Identities = 125/374 (33%), Positives = 211/374 (56%), Gaps = 9/374 (2%)

Query: 19  EEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAF 78
           +++++  F+ +G++  + +   + G+  PT IQ + IP+ L G+D++ +A TGSGKT  F
Sbjct: 91  KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACF 150

Query: 79  ALPILNAL----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
            LP+   L     +T  R  AL+L+PTRELA Q  +  + LG   G+++A+I+GG     
Sbjct: 151 LLPMFERLKTHSAQTGAR--ALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMED 208

Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
           Q  AL + P IIIATPGRL+ H+       L++++Y+V DEADR+  M F  ++ +I+  
Sbjct: 209 QFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIAR 267

Query: 195 IPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYL 254
           +P   +T LFSAT+ K + +  RA L  PV   +    +  E+L+  +  +    K   L
Sbjct: 268 LPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVL 327

Query: 255 VYILNELAG--NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAK 312
           +++L+ +    +  ++F +T ++ +    LL     +   ++  +  + R  +L KF   
Sbjct: 328 LHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLG 387

Query: 313 ARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDV 372
             S L+ TD+A+RGLDIP +D V+N+  P   K ++HRVGR ARAGRSG A + V   ++
Sbjct: 388 KCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEI 447

Query: 373 ELFQRIEHLIGKKL 386
                +   +G+ L
Sbjct: 448 PYLLDLHLFLGRSL 461


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  209 bits (533), Expect = 3e-54
 Identities = 125/374 (33%), Positives = 211/374 (56%), Gaps = 9/374 (2%)

Query: 19  EEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAF 78
           +++++  F+ +G++  + +   + G+  PT IQ + IP+ L G+D++ +A TGSGKT  F
Sbjct: 91  KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACF 150

Query: 79  ALPILNAL----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
            LP+   L     +T  R  AL+L+PTRELA Q  +  + LG   G+++A+I+GG     
Sbjct: 151 LLPMFERLKTHSAQTGAR--ALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMED 208

Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
           Q  AL + P IIIATPGRL+ H+       L++++Y+V DEADR+  M F  ++ +I+  
Sbjct: 209 QFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIAR 267

Query: 195 IPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYL 254
           +P   +T LFSAT+ K + +  RA L  PV   +    +  E+L+  +  +    K   L
Sbjct: 268 LPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVL 327

Query: 255 VYILNELAG--NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAK 312
           +++L+ +    +  ++F +T ++ +    LL     +   ++  +  + R  +L KF   
Sbjct: 328 LHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLG 387

Query: 313 ARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDV 372
             S L+ TD+A+RGLDIP +D V+N+  P   K ++HRVGR ARAGRSG A + V   ++
Sbjct: 388 KCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEI 447

Query: 373 ELFQRIEHLIGKKL 386
                +   +G+ L
Sbjct: 448 PYLLDLHLFLGRSL 461


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  207 bits (527), Expect = 2e-53
 Identities = 127/381 (33%), Positives = 209/381 (54%), Gaps = 9/381 (2%)

Query: 6   EHDSPTEASQP--IVEE---EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
           EH  P E   P  ++E    E    F D+ + + L       G+ KP+ IQ  AI   ++
Sbjct: 11  EHGGP-EGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIK 69

Query: 61  GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
           G D+I  A++G+GKT  FA+ IL  L    +   ALVL PTRELA QI +   ALG  +G
Sbjct: 70  GYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMG 129

Query: 121 VQSAVIVGGIDSMSQSLAL-AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRI 179
                 +GG +  ++   L A+ PHI++ TPGR+ D L N +  + + +K  V+DEAD +
Sbjct: 130 ATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDML-NRRYLSPKWIKMFVLDEADEM 188

Query: 180 LNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQ 239
           L+  F+ ++ +I + +    +  L SATM   V ++ +  +++P++  V  +  T+E ++
Sbjct: 189 LSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIK 248

Query: 240 QYYIFIP-SKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMS 298
           Q+YI +   ++K   L  +   L     +IF +T          +    FT   LHG M 
Sbjct: 249 QFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMD 308

Query: 299 QSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAG 358
           Q +R   + +F++ +  +L+ TD+ +RG+D+  V +V+N+D+PT+ ++YIHR+GR  R G
Sbjct: 309 QKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFG 368

Query: 359 RSGKAITFVTQYDVELFQRIE 379
           R G AI FVT+ D  + + IE
Sbjct: 369 RKGVAINFVTEEDKRILRDIE 389


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  206 bits (523), Expect = 5e-53
 Identities = 127/360 (35%), Positives = 196/360 (54%), Gaps = 16/360 (4%)

Query: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
           K+FK++     +     + G   PT IQI+ IP  L GRD+IG+A TGSGKT  F LP++
Sbjct: 181 KSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVI 240

Query: 84  NALLETPQRL--------FALVLTPTRELAFQ---ISEQFEAL---GSSIGVQSAVIVGG 129
              LE  +RL        + L++ P+RELA Q   I E +  L    SS  ++ A+ +GG
Sbjct: 241 MFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGG 300

Query: 130 IDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVD 189
           +    Q   +    H+++ATPGRL+D L+  K  +L   +YL +DEADR+++M FE ++ 
Sbjct: 301 MSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDIR 359

Query: 190 KILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKF 249
            I       R+T LFSATM KK+Q   ++AL  PV   V         + Q   ++  + 
Sbjct: 360 TIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEA 419

Query: 250 KDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKF 309
           K  YL+  L +      +IF     +       L   G  A+ +HG   Q +R  ++  F
Sbjct: 420 KMVYLLECLQKTPP-PVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAF 478

Query: 310 KAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 369
           +   + +L+ATDVAS+GLD P +  V+N+D+P   ++Y+HR+GRT R+G +G A TF+ +
Sbjct: 479 REGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINK 538


>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
          Length = 547

 Score =  205 bits (521), Expect = 8e-53
 Identities = 147/467 (31%), Positives = 228/467 (48%), Gaps = 58/467 (12%)

Query: 18  VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77
           +E+ E   F+ +G+   L +A   LGW++PT IQ +AIPLAL+G+D++  A TGSGKT A
Sbjct: 1   MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAA 60

Query: 78  FALPILNALLE-------TPQRLFALVLTPTRELAFQISEQFEALGS--SIGVQSAVIVG 128
           +A+P+L  LL          Q +  LVL PT+ELA Q     + L +  +  V+ A +  
Sbjct: 61  YAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSA 120

Query: 129 GIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEV 188
             DS+SQ   L +KP +++ TP R++ HL+        +L+ LV+DEAD + +  FE E+
Sbjct: 121 AEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEEL 180

Query: 189 DKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAV-SSKYQTVEKLQQYYIFIPS 247
             +L  +PR  + FL SAT  + VQ L+   L NPV   +  S+    ++LQQ+ +   +
Sbjct: 181 KSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCET 240

Query: 248 KFKDTYLVYILNELA---GNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLG 304
           +     L+Y L +L+   G S ++F +T   + R  L L         L+G++    R  
Sbjct: 241 EEDKFLLLYALLKLSLIRGKS-LLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCH 299

Query: 305 SLNKFKAKARSILLATDV---------------------------ASRGLDIPHVDVVVN 337
            +++F       ++ATD                             +RG+D  HV  V+N
Sbjct: 300 IISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLN 359

Query: 338 FDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLI-----GKKLPGFPTQ 392
           FD+P   + YIHR GRTARA   G  +TFV   +     +IE L+     G  L  +  +
Sbjct: 360 FDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFR 419

Query: 393 DDEVMMLTERVAEAQR-FARMELRE-----------HGEKKKRSRED 427
            +E+     R  +A R   +  +RE           H EK K   ED
Sbjct: 420 MEEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFED 466


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  204 bits (519), Expect = 1e-52
 Identities = 127/368 (34%), Positives = 203/368 (55%), Gaps = 11/368 (2%)

Query: 12  EASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETG 71
           E ++PI++      F+   + +VL     + G+  PT IQ++ IP+ L GRDI+  A+TG
Sbjct: 197 EVTRPIID------FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTG 250

Query: 72  SGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGI 130
           SGKT AF LP++   L   +   AL+LTPTRELA QI  Q + L S +  +++ ++VGG+
Sbjct: 251 SGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL 310

Query: 131 DSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDK 190
               Q   L +   +IIATPGRL+D ++ +    L  +K +V+DEAD +L M F+ +V  
Sbjct: 311 PLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQVLD 369

Query: 191 ILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK 250
           IL+ IP D +T L SAT+   +++L    L NPV+     K      ++Q  +++    K
Sbjct: 370 ILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAK 429

Query: 251 DTYLVYILNE--LAGNSFMIFCSTCNNTQRTALLLRNL-GFTAIPLHGQMSQSKRLGSLN 307
              L  ILN+  L     ++F          +  ++ + G  +I +H + SQ +R   L 
Sbjct: 430 KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILK 489

Query: 308 KFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 367
                   ++++T V  RGLD+  V +VVNFD+P+   +Y+H++GR  R G++G AITF+
Sbjct: 490 GLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549

Query: 368 TQYDVELF 375
                 LF
Sbjct: 550 NNNSKRLF 557


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  203 bits (516), Expect = 3e-52
 Identities = 119/372 (31%), Positives = 202/372 (54%), Gaps = 3/372 (0%)

Query: 21  EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80
           E   +F D+ +++ L       G+ KP+ IQ  AI   ++G D+I  A++G+GKT  FA+
Sbjct: 29  EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAI 88

Query: 81  PILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL- 139
            IL  +    +   ALVL PTRELA QI +   ALG  +G      +GG +  ++   L 
Sbjct: 89  SILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQ 148

Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
            + PHII+ TPGR+ D L N +  + + +K  V+DEAD +L+  F+ ++  I + +  + 
Sbjct: 149 MEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT 207

Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIP-SKFKDTYLVYIL 258
           +  L SATM   V ++ +  +++P++  V  +  T+E ++Q+YI +   ++K   L  + 
Sbjct: 208 QVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLY 267

Query: 259 NELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILL 318
             L     +IF +T          +    FT   +HG M Q +R   + +F++ +  +L+
Sbjct: 268 ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLI 327

Query: 319 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 378
            TD+ +RG+D+  V +V+N+D+PT+ ++YIHR+GR  R GR G AI  VT+ D    + I
Sbjct: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387

Query: 379 EHLIGKKLPGFP 390
           E      +   P
Sbjct: 388 ETFYNTSIEEMP 399


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  202 bits (514), Expect = 5e-52
 Identities = 144/399 (36%), Positives = 219/399 (54%), Gaps = 20/399 (5%)

Query: 37  EACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQ----- 91
           E   + G+ KPT IQ +A P+ LQG D+IG+A+TG+GKT  + +P    L+  P      
Sbjct: 255 ENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQR 314

Query: 92  -RLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATP 150
            R   LVLTPTRELA Q+  +     S  G++S  + GG +   Q   L K   IIIATP
Sbjct: 315 NRPGMLVLTPTRELALQVEGEC-CKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATP 373

Query: 151 GRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTK 210
           GRL D L+ +   NL+ + YLV+DEAD++L+M FE ++ KIL  +  DR+T + SAT   
Sbjct: 374 GRLND-LQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPH 432

Query: 211 KVQKLQRAALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG-NSFMI 268
            V +L ++ LK P+   V +     V  ++Q  I    + K +++   L  ++  +  ++
Sbjct: 433 SVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIV 492

Query: 269 FCS--TCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRG 326
           F S     +   + L+L N+   +  LHG   Q  R  +L  FK     IL+ATD+ASRG
Sbjct: 493 FVSRKAVADHLSSDLILGNISVES--LHGDREQRDREKALENFKTGKVRILIATDLASRG 550

Query: 327 LDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKL 386
           LD+  V  V NFD P + ++Y+HR+GRT RAGR+G +IT +T+ D  +   + +++ +  
Sbjct: 551 LDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERAN 610

Query: 387 PGFPTQDDEVMMLTERVAEAQRFARMEL---REHGEKKK 422
              P   +E++ + ER    Q+   ME    R  G  KK
Sbjct: 611 QSIP---EELVSMAERFKAHQQKREMERKMERPQGRPKK 646


>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
           sapiens]
          Length = 600

 Score =  201 bits (512), Expect = 9e-52
 Identities = 130/351 (37%), Positives = 197/351 (56%), Gaps = 22/351 (6%)

Query: 38  ACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLF--- 94
           A  +LG+   T +Q   IPL ++ +D+   A TGSGKT AF +PIL  LL   ++L    
Sbjct: 23  ALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRREEKLKKSQ 82

Query: 95  --ALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKP--HIIIATP 150
             A+++TPTRELA QI E            S ++  G  +  + +   K+   +II+ATP
Sbjct: 83  VGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQGGNIIVATP 142

Query: 151 GRLIDHLEN-TKGFNL----RALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFS 205
           GRL D      +G +L    R+L  LV+DEADR+L+M FE  ++ IL+ +P+ R+T LFS
Sbjct: 143 GRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFS 202

Query: 206 ATMTKKVQKLQRAALKNPVKCAV-------SSKYQTVEKLQQYYIFIPSKFKDTYLVYIL 258
           AT T++V+ L RA L+NPV+ +V       SS  +T  +L+ YY+   +  K   LV+ L
Sbjct: 203 ATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQLVHFL 262

Query: 259 NELAGNSFMIFCSTCNNTQRTALLLRNL--GFTAIPLHGQMSQSKRLGSLNKFKAKARSI 316
                   ++F STC   +     L  L  G   + +HG+M + KR     +F+     I
Sbjct: 263 RNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIHGKM-KYKRNKIFMEFRKLQSGI 321

Query: 317 LLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 367
           L+ TDV +RG+DIP V+ V+ +D P+++  ++HR GRTAR G  G A+ F+
Sbjct: 322 LVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFL 372


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,401,639
Number of Sequences: 37866
Number of extensions: 627969
Number of successful extensions: 1957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1705
Number of HSP's gapped (non-prelim): 104
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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