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Search of human proteins with 20149629
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
(455 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 891 0.0
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 769 0.0
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 369 e-102
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 271 9e-73
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 253 2e-67
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 231 8e-61
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 230 2e-60
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 224 1e-58
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 224 1e-58
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 222 5e-58
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 222 5e-58
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 222 5e-58
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 221 8e-58
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 215 8e-56
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 214 1e-55
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 214 2e-55
gi|4758112 HLA-B associated transcript 1 [Homo sapiens] 211 8e-55
gi|18375623 HLA-B associated transcript 1 [Homo sapiens] 211 8e-55
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 210 2e-54
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 210 2e-54
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 210 2e-54
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 209 3e-54
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 209 3e-54
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 207 2e-53
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 206 5e-53
gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens] 205 8e-53
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 204 1e-52
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 203 3e-52
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 202 5e-52
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 201 9e-52
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 891 bits (2302), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 1 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
Sbjct: 1 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
Query: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
Sbjct: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
Query: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
Sbjct: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
Query: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
Sbjct: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
Query: 241 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS
Sbjct: 241 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
Sbjct: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
Query: 361 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 420
GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
Sbjct: 361 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 420
Query: 421 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 455
KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
Sbjct: 421 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 455
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 769 bits (1986), Expect = 0.0
Identities = 406/455 (89%), Positives = 406/455 (89%), Gaps = 49/455 (10%)
Query: 1 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
Sbjct: 1 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
Query: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
Sbjct: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
Query: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
Sbjct: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
Query: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
Sbjct: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
Query: 241 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
YYIFIPSKFK S
Sbjct: 241 YYIFIPSKFK-------------------------------------------------S 251
Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
Sbjct: 252 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 311
Query: 361 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 420
GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
Sbjct: 312 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 371
Query: 421 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 455
KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
Sbjct: 372 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 406
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 369 bits (947), Expect = e-102
Identities = 195/439 (44%), Positives = 275/439 (62%), Gaps = 9/439 (2%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F +LG++ L E C QLG +PT +Q+ IP L+GRD +G A+TGSGKT AF LPIL
Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHI 145
L E P +F LVLTPTRELA+QI+EQF LG +G++ +IVGG+D ++Q+L L++KPH+
Sbjct: 64 LSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHV 123
Query: 146 IIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNM---DFETEVDKILKVIPRDRKTF 202
+IATPGRL DHL ++ F+++ +++LVMDEADR+L DF +++ IL +P R+T
Sbjct: 124 VIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTL 183
Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELA 262
LFSAT+T +++LQ A P + TVE+L Q Y+ +P K KD YLV+++
Sbjct: 184 LFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQ 243
Query: 263 GN----SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILL 318
S +IF +TC Q ++LR F + LH M Q +R +L KFK+ IL+
Sbjct: 244 DEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILI 303
Query: 319 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 378
ATDVASRGLDIP V VV+N + P K YIHRVGRTARAGR G+AIT VTQYD+ L I
Sbjct: 304 ATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAI 363
Query: 379 EHLIGKKLPGFPTQDDEVMMLTERVAEAQRFA--RMELREHGEKKKRSREDAGDNDDTEG 436
E I KKL F ++ EV+ + +V +R ++E EKK+ ++ + +
Sbjct: 364 EEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDP 423
Query: 437 AIGVRNKVAGGKMKKRKGR 455
+ + K K+K++ R
Sbjct: 424 DLEAKRKAELAKIKQKNRR 442
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 271 bits (693), Expect = 9e-73
Identities = 154/417 (36%), Positives = 244/417 (58%), Gaps = 6/417 (1%)
Query: 21 EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80
+E +F+D+ ++ L +A +G+ +PT IQ IP+ L G+DI A TG+GKT AFAL
Sbjct: 215 DENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFAL 274
Query: 81 PILNALLETPQRL---FALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSL 137
P+L L+ P++ LVL PTREL Q+ L + + + VGG+D SQ
Sbjct: 275 PVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEA 334
Query: 138 ALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPR 197
AL P I+IATPGRLIDHL N F+L +++ L++DEADR+L+ FE ++ +I+++
Sbjct: 335 ALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSH 394
Query: 198 DRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI-PSK--FKDTYL 254
R+T LFSATMT +V+ L +LKNPV+ V+S L+Q +I I P++ ++ +
Sbjct: 395 HRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIV 454
Query: 255 VYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKAR 314
+L + M+F T R +LL +G LHG +SQ++RL +L +FK +
Sbjct: 455 AALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQI 514
Query: 315 SILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVEL 374
IL+ATDVA+RGLDI V V+NF +P K Y+HRVGRTARAGR+G++++ V + + ++
Sbjct: 515 DILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKM 574
Query: 375 FQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDN 431
+ I + D ++ +++ + ++ L+ E+K+ + +A N
Sbjct: 575 LKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQIN 631
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 253 bits (647), Expect = 2e-67
Identities = 150/394 (38%), Positives = 224/394 (56%), Gaps = 36/394 (9%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
+++KD + + E D+ G+ +PT IQ +AIP+ LQ RDIIG+AETGSGKT AF +P+L
Sbjct: 391 RSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLL 450
Query: 84 ---------NALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
+ + E+ Q +A++L PTRELA QI E+ G +G+++ ++GGI
Sbjct: 451 VWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISRED 510
Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
Q L I+IATPGRLID LEN + L Y+V+DEADR+++M FE +V KIL+
Sbjct: 511 QGFRLRMGCEIVIATPGRLIDVLEN-RYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEH 569
Query: 195 IP--------------------------RDRKTFLFSATMTKKVQKLQRAALKNPVKCAV 228
+P + R+T +F+ATM V++L R+ L+ P +
Sbjct: 570 MPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYI 629
Query: 229 SSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGF 288
S + E+++Q + K L+ IL + +IF + A L +G+
Sbjct: 630 GSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGY 689
Query: 289 TAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYI 348
A LHG Q +R +L+ KA A+ IL+ATDVA RG+DI V +VVN+D+ + +DYI
Sbjct: 690 NACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYI 749
Query: 349 HRVGRTARAGRSGKAITFVTQYDVELFQRIEHLI 382
HR+GRT RAG+SG AITF+T+ D +F ++ I
Sbjct: 750 HRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAI 783
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 231 bits (590), Expect = 8e-61
Identities = 141/416 (33%), Positives = 229/416 (55%), Gaps = 17/416 (4%)
Query: 18 VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77
+ E F D ++ + + + T+IQ + I LALQG+D++G A+TGSGKT A
Sbjct: 63 INVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLA 122
Query: 78 FALPILNALLE----TPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSM 133
F +P+L AL + L L+++PTRELA+Q E +G + + +I+GG D
Sbjct: 123 FLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
Query: 134 SQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILK 193
++ + +I++ TPGRL+ H++ T F+ L+ LV+DEADRIL+M F ++ +++
Sbjct: 183 HEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
Query: 194 VIPRDRKTFLFSATMTKKVQKLQRAALKNP--VKCAVSSKYQTVEKLQQYYIFIPSKFKD 251
+P+ R+T LFSAT TK V+ L R +LKNP V +KY T L+Q YI + K
Sbjct: 242 NLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKI 301
Query: 252 TYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNL--GFTAIPLHGQMSQSKRLGSLNKF 309
+ L L ++F S+C Q + L G + + LHG+ Q +R+ N+F
Sbjct: 302 SVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEF 361
Query: 310 KAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 369
K ++L ATD+A+RGLD P V+ V+ FD P + YIHR GRTAR G+A+ +
Sbjct: 362 VRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLP 421
Query: 370 YDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSR 425
+ + ++ L+ KK+P E+ + E++ + Q+ L + + K+R++
Sbjct: 422 SEKAM---VQQLLQKKVP-----VKEIKINPEKLIDVQKKLESILAQDQDLKERAQ 469
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 230 bits (587), Expect = 2e-60
Identities = 146/447 (32%), Positives = 235/447 (52%), Gaps = 27/447 (6%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
K++ G++ + + + G+ KPT IQ +AIP + GRD+IG+A+TGSGKT AF LP+
Sbjct: 372 KSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMF 431
Query: 84 NAL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLA 138
+ LE + A+++TPTRELA QI+++ + ++G++ + GG Q
Sbjct: 432 RHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAE 491
Query: 139 LAKKPHIIIATPGRLIDHLENTKG--FNLRALKYLVMDEADRILNMDFETEVDKILKVIP 196
L + II+ TPGR+ID L G NLR + Y+V+DEADR+ +M FE +V +I+ +
Sbjct: 492 LKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVR 551
Query: 197 RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVY 256
DR+T +FSAT + ++ L R L P++ V + ++Q I I + K L+
Sbjct: 552 PDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLE 611
Query: 257 ILNELA-GNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315
+L S +IF + L + + LHG + Q R +N FK
Sbjct: 612 LLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCK 671
Query: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ----YD 371
+L+AT VA+RGLD+ H+ +VVN+ P H +DY+HR GRT RAG G A TF+T+ Y
Sbjct: 672 LLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYA 731
Query: 372 VELFQRIEHLIGKKLP--------GFPTQDDEVMMLTERVA----EAQRFARMELREHGE 419
++ + +E L G +P F Q + ++ + + +F E E
Sbjct: 732 GDIIKALE-LSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANE 790
Query: 420 KKKRSREDAG--DNDDTEGAIGVRNKV 444
+KK + G D+DD + A+ + ++
Sbjct: 791 RKKLQKAALGLQDSDDEDAAVDIDEQI 817
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 224 bits (571), Expect = 1e-58
Identities = 136/356 (38%), Positives = 200/356 (56%), Gaps = 12/356 (3%)
Query: 25 TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84
+F G + L + +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF P+L
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
Query: 85 AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139
+ LE A+++ PTREL QI + + G + ++S + GG Q+ AL
Sbjct: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
+ I++ TPGRLIDH++ K NL+ + YLV DEADR+ +M FE +V I + DR
Sbjct: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432
Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKFKDTYLVY 256
+T LFSAT KK++KL R L +P++ + E + Q + PSK+ +L
Sbjct: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN--WLTR 490
Query: 257 ILNELAGN-SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315
L E + S ++F + N + A L+ G LHG M QS+R ++ FK K
Sbjct: 491 RLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIP 550
Query: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 371
+L+ATDVA+RGLDIP + V+N+D+ + HR+GRT RAG G A T +T D
Sbjct: 551 VLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 224 bits (571), Expect = 1e-58
Identities = 136/356 (38%), Positives = 200/356 (56%), Gaps = 12/356 (3%)
Query: 25 TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84
+F G + L + +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF P+L
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
Query: 85 AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139
+ LE A+++ PTREL QI + + G + ++S + GG Q+ AL
Sbjct: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
+ I++ TPGRLIDH++ K NL+ + YLV DEADR+ +M FE +V I + DR
Sbjct: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432
Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKFKDTYLVY 256
+T LFSAT KK++KL R L +P++ + E + Q + PSK+ +L
Sbjct: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN--WLTR 490
Query: 257 ILNELAGN-SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315
L E + S ++F + N + A L+ G LHG M QS+R ++ FK K
Sbjct: 491 RLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIP 550
Query: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 371
+L+ATDVA+RGLDIP + V+N+D+ + HR+GRT RAG G A T +T D
Sbjct: 551 VLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 222 bits (566), Expect = 5e-58
Identities = 150/397 (37%), Positives = 211/397 (53%), Gaps = 34/397 (8%)
Query: 44 WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
+T+PT IQ + PLAL GRD++G+A+TGSGKT A+ LP + LE LVL
Sbjct: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250
Query: 99 TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
PTRELA Q+ + + G ++S I GG Q L + I IATPGRLID LE
Sbjct: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310
Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
+ K NLR YLV+DEADR+L+M FE ++ KI+ I DR+T ++SAT K+V++L
Sbjct: 311 SGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 369
Query: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274
L++ + V + + + Q KD L+ ++ E+ N +IF T
Sbjct: 370 FLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKR 429
Query: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334
+R G+ A+ +HG SQ +R LN+F++ IL+ATDVASRGLD+ V
Sbjct: 430 RCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKF 489
Query: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDD 394
V+N+D P S+DY+HR+GRTAR+ G A TF T PG Q
Sbjct: 490 VINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT------------------PGNLKQAR 531
Query: 395 EVMMLTERVAEAQRFARMELREH------GEKKKRSR 425
E++ + E +A M+L +H G K RSR
Sbjct: 532 ELIKVLEEANQAINPKLMQLVDHRGGGGGGGKGGRSR 568
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 222 bits (566), Expect = 5e-58
Identities = 125/395 (31%), Positives = 212/395 (53%), Gaps = 9/395 (2%)
Query: 5 EEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDI 64
+E D + E + T TF +G+ + L G+ KP+ IQ AI ++GRD+
Sbjct: 19 KEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDV 78
Query: 65 IGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSA 124
I +++G+GKT F++ +L L + AL+L PTRELA QI + ALG + VQ
Sbjct: 79 IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCH 138
Query: 125 VIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDF 184
+GG + L H++ TPGR+ D + + RA+K LV+DEAD +LN F
Sbjct: 139 ACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLNKGF 197
Query: 185 ETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIF 244
+ ++ + + +P + L SAT+ ++ ++ + +P++ V T+E ++Q+++
Sbjct: 198 KEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257
Query: 245 IP-SKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRL 303
+ ++K L + + L +IFC+T +R FT +HG M Q +R
Sbjct: 258 VEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERE 317
Query: 304 GSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKA 363
+ +F++ A +L++TDV +RGLD+P V +++N+D+P + + YIHR+GR+ R GR G A
Sbjct: 318 SIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA 377
Query: 364 ITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMM 398
I FV D+ + + IE + TQ DE+ M
Sbjct: 378 INFVKNDDIRILRDIEQY-------YSTQIDEMPM 405
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 222 bits (566), Expect = 5e-58
Identities = 134/339 (39%), Positives = 205/339 (60%), Gaps = 8/339 (2%)
Query: 31 VTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLET- 89
V + +A ++G+T T+IQ ++I L+GRD++ A+TGSGKT AF +P + +++
Sbjct: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
Query: 90 --PQR-LFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHII 146
P+ L+L+PTRELA Q + L + +I+GG + +++ L +II
Sbjct: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINII 305
Query: 147 IATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSA 206
+ATPGRL+DH++NT GF + L+ LV+DEADRIL++ FE E+ +I+K++P R+T LFSA
Sbjct: 306 VATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSA 365
Query: 207 TMTKKVQKLQRAAL-KNPVKCAV--SSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG 263
T T+KV+ L R +L K P+ V TV+ L+Q Y+ PS+ + L L +
Sbjct: 366 TQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRK 425
Query: 264 NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVA 323
M+F S+C + + LL + + +HG+ Q+KR + +F LL TDVA
Sbjct: 426 KKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVA 485
Query: 324 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGK 362
+RGLDIP VD +V +D P K+YIHRVGRTAR G +G+
Sbjct: 486 ARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGR 523
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 221 bits (564), Expect = 8e-58
Identities = 145/383 (37%), Positives = 206/383 (53%), Gaps = 28/383 (7%)
Query: 44 WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
+T+PT IQ + PLAL GRD++G+A+TGSGKT A+ LP + LE LVL
Sbjct: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250
Query: 99 TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
PTRELA Q+ + + G ++S I GG Q L + I IATPGRLID LE
Sbjct: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310
Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
+ K NLR YLV+DEADR+L+M FE ++ KI+ I DR+T ++SAT K+V++L
Sbjct: 311 SGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 369
Query: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274
L++ + V + + + Q KD L+ ++ E+ N +IF T
Sbjct: 370 FLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKR 429
Query: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334
+R G+ A+ +HG SQ +R LN+F++ IL+ATDVASRGLD+ V
Sbjct: 430 RCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKF 489
Query: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDD 394
V+N+D P S+DY+HR+GRTAR+ G A TF T PG Q
Sbjct: 490 VINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT------------------PGNLKQAR 531
Query: 395 EVMMLTERVAEAQRFARMELREH 417
E++ + E +A M+L +H
Sbjct: 532 ELIKVLEEANQAINPKLMQLVDH 554
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 215 bits (547), Expect = 8e-56
Identities = 123/382 (32%), Positives = 214/382 (56%), Gaps = 5/382 (1%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F+D + L ++GW KP+ IQ E+IP+AL GRDI+ A+ G+GK+GA+ +P+L
Sbjct: 98 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSIG-VQSAVIVGGIDSMSQSLALAKKPH 144
L + A+V+ PTRELA Q+S+ + +G + GG + + L H
Sbjct: 158 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217
Query: 145 IIIATPGRLIDHLENTKGF-NLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFL 203
++IATPGR++D ++ KG + ++ +V+DEAD++L+ DF ++ I+ +P++R+ L
Sbjct: 218 VVIATPGRILDLIK--KGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILL 275
Query: 204 FSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG 263
+SAT VQK + L+ P + + + T++ + QYY ++ + K L + + L
Sbjct: 276 YSATFPLSVQKFMNSHLQKPYEINLMEEL-TLKGVTQYYAYVTERQKVHCLNTLFSRLQI 334
Query: 264 NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVA 323
N +IFC++ + A + LG++ +H +M Q R + F+ L+ TD+
Sbjct: 335 NQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLF 394
Query: 324 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIG 383
+RG+DI V+VV+NFD P ++ Y+HR+GR+ R G G AI +T D + IE +G
Sbjct: 395 TRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLG 454
Query: 384 KKLPGFPTQDDEVMMLTERVAE 405
++ P+ D+ + + E +E
Sbjct: 455 TEIKPIPSNIDKSLYVAEYHSE 476
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 214 bits (545), Expect = 1e-55
Identities = 131/382 (34%), Positives = 210/382 (54%), Gaps = 24/382 (6%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
++F D+ + +++ + +T+PT +Q AIP+ + RD++ A+TGSGKT AF LPIL
Sbjct: 180 ESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPIL 239
Query: 84 NALLET------------------PQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
+ + Q +LVL PTRELA QI E+ V+ V
Sbjct: 240 SQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 299
Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
+ GG D Q L + H+++ATPGRL+D +E K L KYLV+DEADR+L+M FE
Sbjct: 300 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 358
Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
++ +I++ + P+ R T +FSAT K++Q L R L + AV T E + Q
Sbjct: 359 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 418
Query: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
+++ K ++L+ +LN +S ++F T L + G+ +HG SQ
Sbjct: 419 VVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 478
Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
R +L++F++ IL+AT VA+RGLDI +V V+NFD+P+ ++Y+HR+GRT R G
Sbjct: 479 DREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNL 538
Query: 361 GKAITFVTQYDVELFQRIEHLI 382
G A +F + ++ + + + L+
Sbjct: 539 GLATSFFNERNINITKDLLDLL 560
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 214 bits (544), Expect = 2e-55
Identities = 133/339 (39%), Positives = 192/339 (56%), Gaps = 10/339 (2%)
Query: 44 WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
+T+PT IQ + P+AL G D++G+A+TGSGKT ++ LP + LE LVL
Sbjct: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
Query: 99 TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
PTRELA Q+ + + ++S I GG Q L + I IATPGRLID LE
Sbjct: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
K NLR YLV+DEADR+L+M FE ++ KI+ I DR+T ++SAT K+V++L
Sbjct: 234 CGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 292
Query: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274
LK+ + + + + + Q KD L+ ++ E+ N ++F T
Sbjct: 293 FLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKR 352
Query: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334
+R G+ A+ +HG SQ +R LN+FK IL+ATDVASRGLD+ V
Sbjct: 353 RCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKF 412
Query: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVE 373
V+N+D P S+DYIHR+GRTAR+ ++G A TF T +++
Sbjct: 413 VINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK 451
>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 211 bits (538), Expect = 8e-55
Identities = 125/374 (33%), Positives = 206/374 (55%), Gaps = 6/374 (1%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F+D + L A G+ P+++Q E IP A+ G D++ A++G GKT F L L
Sbjct: 47 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
L ++ LV+ TRELAFQIS+++E + V+ AV GG+ L K P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166
Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILN-MDFETEVDKILKVIPRDRKTF 202
HI++ TPGR++ L K NL+ +K+ ++DE D++L +D +V +I ++ P +++
Sbjct: 167 HIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVM 225
Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKDTYLVYILNEL 261
+FSAT++K+++ + R +++P++ V + + T+ LQQYY+ + K+ L +L+ L
Sbjct: 226 MFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVL 285
Query: 262 AGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATD 321
N +IF + A LL F AI +H M Q +RL +FK R IL+AT+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345
Query: 322 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 380
+ RG+DI V++ N+D+P S Y+HRV R R G G AITFV+ + D ++ ++
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405
Query: 381 LIGKKLPGFPTQDD 394
+ P + D
Sbjct: 406 RFEVNISELPDEID 419
>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 211 bits (538), Expect = 8e-55
Identities = 125/374 (33%), Positives = 206/374 (55%), Gaps = 6/374 (1%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F+D + L A G+ P+++Q E IP A+ G D++ A++G GKT F L L
Sbjct: 47 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
L ++ LV+ TRELAFQIS+++E + V+ AV GG+ L K P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166
Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILN-MDFETEVDKILKVIPRDRKTF 202
HI++ TPGR++ L K NL+ +K+ ++DE D++L +D +V +I ++ P +++
Sbjct: 167 HIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVM 225
Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKDTYLVYILNEL 261
+FSAT++K+++ + R +++P++ V + + T+ LQQYY+ + K+ L +L+ L
Sbjct: 226 MFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVL 285
Query: 262 AGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATD 321
N +IF + A LL F AI +H M Q +RL +FK R IL+AT+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345
Query: 322 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 380
+ RG+DI V++ N+D+P S Y+HRV R R G G AITFV+ + D ++ ++
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405
Query: 381 LIGKKLPGFPTQDD 394
+ P + D
Sbjct: 406 RFEVNISELPDEID 419
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 210 bits (535), Expect = 2e-54
Identities = 131/382 (34%), Positives = 207/382 (54%), Gaps = 24/382 (6%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
+ F D+ + +++ + +T+PT +Q AIP+ RD++ A+TGSGKT AF LPIL
Sbjct: 178 ENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPIL 237
Query: 84 NALL------------------ETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
+ + Q +LVL PTRELA QI E+ V+ V
Sbjct: 238 SQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 297
Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
+ GG D Q L + H+++ATPGRL+D +E K L KYLV+DEADR+L+M FE
Sbjct: 298 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 356
Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
++ +I++ + P+ R T +FSAT K++Q L R L + AV T E + Q
Sbjct: 357 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 416
Query: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
+++ K ++L+ IL +S ++F T L + G+ +HG SQ
Sbjct: 417 VVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 476
Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
R +L++F++ IL+AT VA+RGLDI +V V+NFD+P+ ++Y+HR+GRT R G
Sbjct: 477 DREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL 536
Query: 361 GKAITFVTQYDVELFQRIEHLI 382
G A +F + ++ + + + L+
Sbjct: 537 GLATSFFNEKNMNITKDLLDLL 558
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 210 bits (535), Expect = 2e-54
Identities = 131/382 (34%), Positives = 207/382 (54%), Gaps = 24/382 (6%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
+ F D+ + +++ + +T+PT +Q AIP+ RD++ A+TGSGKT AF LPIL
Sbjct: 178 ENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPIL 237
Query: 84 NALL------------------ETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
+ + Q +LVL PTRELA QI E+ V+ V
Sbjct: 238 SQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 297
Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
+ GG D Q L + H+++ATPGRL+D +E K L KYLV+DEADR+L+M FE
Sbjct: 298 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 356
Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
++ +I++ + P+ R T +FSAT K++Q L R L + AV T E + Q
Sbjct: 357 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 416
Query: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
+++ K ++L+ IL +S ++F T L + G+ +HG SQ
Sbjct: 417 VVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 476
Query: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
R +L++F++ IL+AT VA+RGLDI +V V+NFD+P+ ++Y+HR+GRT R G
Sbjct: 477 DREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL 536
Query: 361 GKAITFVTQYDVELFQRIEHLI 382
G A +F + ++ + + + L+
Sbjct: 537 GLATSFFNEKNMNITKDLLDLL 558
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 210 bits (535), Expect = 2e-54
Identities = 123/374 (32%), Positives = 209/374 (55%), Gaps = 6/374 (1%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F+D + L A G+ P+++Q E IP A+ G D++ A++G GKT F L L
Sbjct: 46 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 105
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
+ ++ LV+ TRELAFQIS+++E + V+ +V GG+ L K P
Sbjct: 106 IEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCP 165
Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILN-MDFETEVDKILKVIPRDRKTF 202
H+++ TPGR++ + N + F+L+ +K+ V+DE D++L +D +V +I ++ P +++
Sbjct: 166 HVVVGTPGRILALVRN-RSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCM 224
Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKDTYLVYILNEL 261
+FSAT++K ++ + R +++P++ V + + T+ LQQYY+ + K+ L +L+ L
Sbjct: 225 MFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVL 284
Query: 262 AGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATD 321
N +IF + A LL F AI +H M+Q +RL +FK R IL+AT+
Sbjct: 285 EFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATN 344
Query: 322 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 380
+ RG+DI V++V N+D+P S Y+HRV R R G G AITFV+ + D ++ ++
Sbjct: 345 LFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 404
Query: 381 LIGKKLPGFPTQDD 394
+ P + D
Sbjct: 405 RFEVNVAELPEEID 418
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 209 bits (533), Expect = 3e-54
Identities = 125/374 (33%), Positives = 211/374 (56%), Gaps = 9/374 (2%)
Query: 19 EEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAF 78
+++++ F+ +G++ + + + G+ PT IQ + IP+ L G+D++ +A TGSGKT F
Sbjct: 91 KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACF 150
Query: 79 ALPILNAL----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
LP+ L +T R AL+L+PTRELA Q + + LG G+++A+I+GG
Sbjct: 151 LLPMFERLKTHSAQTGAR--ALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMED 208
Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
Q AL + P IIIATPGRL+ H+ L++++Y+V DEADR+ M F ++ +I+
Sbjct: 209 QFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIAR 267
Query: 195 IPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYL 254
+P +T LFSAT+ K + + RA L PV + + E+L+ + + K L
Sbjct: 268 LPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVL 327
Query: 255 VYILNELAG--NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAK 312
+++L+ + + ++F +T ++ + LL + ++ + + R +L KF
Sbjct: 328 LHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLG 387
Query: 313 ARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDV 372
S L+ TD+A+RGLDIP +D V+N+ P K ++HRVGR ARAGRSG A + V ++
Sbjct: 388 KCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEI 447
Query: 373 ELFQRIEHLIGKKL 386
+ +G+ L
Sbjct: 448 PYLLDLHLFLGRSL 461
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 209 bits (533), Expect = 3e-54
Identities = 125/374 (33%), Positives = 211/374 (56%), Gaps = 9/374 (2%)
Query: 19 EEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAF 78
+++++ F+ +G++ + + + G+ PT IQ + IP+ L G+D++ +A TGSGKT F
Sbjct: 91 KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACF 150
Query: 79 ALPILNAL----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
LP+ L +T R AL+L+PTRELA Q + + LG G+++A+I+GG
Sbjct: 151 LLPMFERLKTHSAQTGAR--ALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMED 208
Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
Q AL + P IIIATPGRL+ H+ L++++Y+V DEADR+ M F ++ +I+
Sbjct: 209 QFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIAR 267
Query: 195 IPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYL 254
+P +T LFSAT+ K + + RA L PV + + E+L+ + + K L
Sbjct: 268 LPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVL 327
Query: 255 VYILNELAG--NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAK 312
+++L+ + + ++F +T ++ + LL + ++ + + R +L KF
Sbjct: 328 LHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLG 387
Query: 313 ARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDV 372
S L+ TD+A+RGLDIP +D V+N+ P K ++HRVGR ARAGRSG A + V ++
Sbjct: 388 KCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEI 447
Query: 373 ELFQRIEHLIGKKL 386
+ +G+ L
Sbjct: 448 PYLLDLHLFLGRSL 461
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 207 bits (527), Expect = 2e-53
Identities = 127/381 (33%), Positives = 209/381 (54%), Gaps = 9/381 (2%)
Query: 6 EHDSPTEASQP--IVEE---EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
EH P E P ++E E F D+ + + L G+ KP+ IQ AI ++
Sbjct: 11 EHGGP-EGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIK 69
Query: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
G D+I A++G+GKT FA+ IL L + ALVL PTRELA QI + ALG +G
Sbjct: 70 GYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMG 129
Query: 121 VQSAVIVGGIDSMSQSLAL-AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRI 179
+GG + ++ L A+ PHI++ TPGR+ D L N + + + +K V+DEAD +
Sbjct: 130 ATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDML-NRRYLSPKWIKMFVLDEADEM 188
Query: 180 LNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQ 239
L+ F+ ++ +I + + + L SATM V ++ + +++P++ V + T+E ++
Sbjct: 189 LSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIK 248
Query: 240 QYYIFIP-SKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMS 298
Q+YI + ++K L + L +IF +T + FT LHG M
Sbjct: 249 QFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMD 308
Query: 299 QSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAG 358
Q +R + +F++ + +L+ TD+ +RG+D+ V +V+N+D+PT+ ++YIHR+GR R G
Sbjct: 309 QKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFG 368
Query: 359 RSGKAITFVTQYDVELFQRIE 379
R G AI FVT+ D + + IE
Sbjct: 369 RKGVAINFVTEEDKRILRDIE 389
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 206 bits (523), Expect = 5e-53
Identities = 127/360 (35%), Positives = 196/360 (54%), Gaps = 16/360 (4%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
K+FK++ + + G PT IQI+ IP L GRD+IG+A TGSGKT F LP++
Sbjct: 181 KSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVI 240
Query: 84 NALLETPQRL--------FALVLTPTRELAFQ---ISEQFEAL---GSSIGVQSAVIVGG 129
LE +RL + L++ P+RELA Q I E + L SS ++ A+ +GG
Sbjct: 241 MFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGG 300
Query: 130 IDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVD 189
+ Q + H+++ATPGRL+D L+ K +L +YL +DEADR+++M FE ++
Sbjct: 301 MSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDIR 359
Query: 190 KILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKF 249
I R+T LFSATM KK+Q ++AL PV V + Q ++ +
Sbjct: 360 TIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEA 419
Query: 250 KDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKF 309
K YL+ L + +IF + L G A+ +HG Q +R ++ F
Sbjct: 420 KMVYLLECLQKTPP-PVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAF 478
Query: 310 KAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 369
+ + +L+ATDVAS+GLD P + V+N+D+P ++Y+HR+GRT R+G +G A TF+ +
Sbjct: 479 REGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINK 538
>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
Length = 547
Score = 205 bits (521), Expect = 8e-53
Identities = 147/467 (31%), Positives = 228/467 (48%), Gaps = 58/467 (12%)
Query: 18 VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77
+E+ E F+ +G+ L +A LGW++PT IQ +AIPLAL+G+D++ A TGSGKT A
Sbjct: 1 MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAA 60
Query: 78 FALPILNALLE-------TPQRLFALVLTPTRELAFQISEQFEALGS--SIGVQSAVIVG 128
+A+P+L LL Q + LVL PT+ELA Q + L + + V+ A +
Sbjct: 61 YAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSA 120
Query: 129 GIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEV 188
DS+SQ L +KP +++ TP R++ HL+ +L+ LV+DEAD + + FE E+
Sbjct: 121 AEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEEL 180
Query: 189 DKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAV-SSKYQTVEKLQQYYIFIPS 247
+L +PR + FL SAT + VQ L+ L NPV + S+ ++LQQ+ + +
Sbjct: 181 KSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCET 240
Query: 248 KFKDTYLVYILNELA---GNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLG 304
+ L+Y L +L+ G S ++F +T + R L L L+G++ R
Sbjct: 241 EEDKFLLLYALLKLSLIRGKS-LLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCH 299
Query: 305 SLNKFKAKARSILLATDV---------------------------ASRGLDIPHVDVVVN 337
+++F ++ATD +RG+D HV V+N
Sbjct: 300 IISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLN 359
Query: 338 FDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLI-----GKKLPGFPTQ 392
FD+P + YIHR GRTARA G +TFV + +IE L+ G L + +
Sbjct: 360 FDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFR 419
Query: 393 DDEVMMLTERVAEAQR-FARMELRE-----------HGEKKKRSRED 427
+E+ R +A R + +RE H EK K ED
Sbjct: 420 MEEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFED 466
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 204 bits (519), Expect = 1e-52
Identities = 127/368 (34%), Positives = 203/368 (55%), Gaps = 11/368 (2%)
Query: 12 EASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETG 71
E ++PI++ F+ + +VL + G+ PT IQ++ IP+ L GRDI+ A+TG
Sbjct: 197 EVTRPIID------FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTG 250
Query: 72 SGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGI 130
SGKT AF LP++ L + AL+LTPTRELA QI Q + L S + +++ ++VGG+
Sbjct: 251 SGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL 310
Query: 131 DSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDK 190
Q L + +IIATPGRL+D ++ + L +K +V+DEAD +L M F+ +V
Sbjct: 311 PLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQVLD 369
Query: 191 ILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK 250
IL+ IP D +T L SAT+ +++L L NPV+ K ++Q +++ K
Sbjct: 370 ILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAK 429
Query: 251 DTYLVYILNE--LAGNSFMIFCSTCNNTQRTALLLRNL-GFTAIPLHGQMSQSKRLGSLN 307
L ILN+ L ++F + ++ + G +I +H + SQ +R L
Sbjct: 430 KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILK 489
Query: 308 KFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 367
++++T V RGLD+ V +VVNFD+P+ +Y+H++GR R G++G AITF+
Sbjct: 490 GLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549
Query: 368 TQYDVELF 375
LF
Sbjct: 550 NNNSKRLF 557
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 203 bits (516), Expect = 3e-52
Identities = 119/372 (31%), Positives = 202/372 (54%), Gaps = 3/372 (0%)
Query: 21 EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80
E +F D+ +++ L G+ KP+ IQ AI ++G D+I A++G+GKT FA+
Sbjct: 29 EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAI 88
Query: 81 PILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL- 139
IL + + ALVL PTRELA QI + ALG +G +GG + ++ L
Sbjct: 89 SILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQ 148
Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
+ PHII+ TPGR+ D L N + + + +K V+DEAD +L+ F+ ++ I + + +
Sbjct: 149 MEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT 207
Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIP-SKFKDTYLVYIL 258
+ L SATM V ++ + +++P++ V + T+E ++Q+YI + ++K L +
Sbjct: 208 QVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLY 267
Query: 259 NELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILL 318
L +IF +T + FT +HG M Q +R + +F++ + +L+
Sbjct: 268 ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLI 327
Query: 319 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 378
TD+ +RG+D+ V +V+N+D+PT+ ++YIHR+GR R GR G AI VT+ D + I
Sbjct: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387
Query: 379 EHLIGKKLPGFP 390
E + P
Sbjct: 388 ETFYNTSIEEMP 399
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 202 bits (514), Expect = 5e-52
Identities = 144/399 (36%), Positives = 219/399 (54%), Gaps = 20/399 (5%)
Query: 37 EACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQ----- 91
E + G+ KPT IQ +A P+ LQG D+IG+A+TG+GKT + +P L+ P
Sbjct: 255 ENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQR 314
Query: 92 -RLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATP 150
R LVLTPTRELA Q+ + S G++S + GG + Q L K IIIATP
Sbjct: 315 NRPGMLVLTPTRELALQVEGEC-CKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATP 373
Query: 151 GRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTK 210
GRL D L+ + NL+ + YLV+DEAD++L+M FE ++ KIL + DR+T + SAT
Sbjct: 374 GRLND-LQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPH 432
Query: 211 KVQKLQRAALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG-NSFMI 268
V +L ++ LK P+ V + V ++Q I + K +++ L ++ + ++
Sbjct: 433 SVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIV 492
Query: 269 FCS--TCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRG 326
F S + + L+L N+ + LHG Q R +L FK IL+ATD+ASRG
Sbjct: 493 FVSRKAVADHLSSDLILGNISVES--LHGDREQRDREKALENFKTGKVRILIATDLASRG 550
Query: 327 LDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKL 386
LD+ V V NFD P + ++Y+HR+GRT RAGR+G +IT +T+ D + + +++ +
Sbjct: 551 LDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERAN 610
Query: 387 PGFPTQDDEVMMLTERVAEAQRFARMEL---REHGEKKK 422
P +E++ + ER Q+ ME R G KK
Sbjct: 611 QSIP---EELVSMAERFKAHQQKREMERKMERPQGRPKK 646
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
sapiens]
Length = 600
Score = 201 bits (512), Expect = 9e-52
Identities = 130/351 (37%), Positives = 197/351 (56%), Gaps = 22/351 (6%)
Query: 38 ACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLF--- 94
A +LG+ T +Q IPL ++ +D+ A TGSGKT AF +PIL LL ++L
Sbjct: 23 ALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRREEKLKKSQ 82
Query: 95 --ALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKP--HIIIATP 150
A+++TPTRELA QI E S ++ G + + + K+ +II+ATP
Sbjct: 83 VGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQGGNIIVATP 142
Query: 151 GRLIDHLEN-TKGFNL----RALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFS 205
GRL D +G +L R+L LV+DEADR+L+M FE ++ IL+ +P+ R+T LFS
Sbjct: 143 GRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFS 202
Query: 206 ATMTKKVQKLQRAALKNPVKCAV-------SSKYQTVEKLQQYYIFIPSKFKDTYLVYIL 258
AT T++V+ L RA L+NPV+ +V SS +T +L+ YY+ + K LV+ L
Sbjct: 203 ATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQLVHFL 262
Query: 259 NELAGNSFMIFCSTCNNTQRTALLLRNL--GFTAIPLHGQMSQSKRLGSLNKFKAKARSI 316
++F STC + L L G + +HG+M + KR +F+ I
Sbjct: 263 RNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIHGKM-KYKRNKIFMEFRKLQSGI 321
Query: 317 LLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 367
L+ TDV +RG+DIP V+ V+ +D P+++ ++HR GRTAR G G A+ F+
Sbjct: 322 LVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFL 372
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,401,639
Number of Sequences: 37866
Number of extensions: 627969
Number of successful extensions: 1957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1705
Number of HSP's gapped (non-prelim): 104
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.