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Search of human proteins with 199559954
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|199559954 coiled-coil domain containing 78 [Homo sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|199559954 coiled-coil domain containing 78 [Homo sapiens] 887 0.0
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is... 46 6e-05
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso... 46 6e-05
gi|4504063 golgin 97 [Homo sapiens] 42 0.001
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom... 42 0.001
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 41 0.002
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 41 0.002
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 41 0.002
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 41 0.002
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 41 0.002
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 41 0.002
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 40 0.005
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 40 0.005
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 40 0.005
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 40 0.005
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 40 0.005
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 40 0.005
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 40 0.005
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 40 0.005
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 39 0.012
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 39 0.012
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 39 0.012
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 39 0.012
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 38 0.016
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 37 0.027
gi|8922940 gamma-taxilin [Homo sapiens] 37 0.035
gi|122692281 hypothetical protein LOC645369 [Homo sapiens] 37 0.035
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 37 0.035
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 37 0.046
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens] 36 0.060
>gi|199559954 coiled-coil domain containing 78 [Homo sapiens]
Length = 438
Score = 887 bits (2291), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MEHAATTGPRPGPPSRRVENVVLRAKDWLPGAPGGTAVWATSLEAEVPPDLALNKEQQLQ 60
MEHAATTGPRPGPPSRRVENVVLRAKDWLPGAPGGTAVWATSLEAEVPPDLALNKEQQLQ
Sbjct: 1 MEHAATTGPRPGPPSRRVENVVLRAKDWLPGAPGGTAVWATSLEAEVPPDLALNKEQQLQ 60
Query: 61 ISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPR 120
ISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPR
Sbjct: 61 ISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPR 120
Query: 121 HPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQ 180
HPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQ
Sbjct: 121 HPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQ 180
Query: 181 QALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLK 240
QALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLK
Sbjct: 181 QALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLK 240
Query: 241 DEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYH 300
DEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYH
Sbjct: 241 DEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYH 300
Query: 301 KRLVDLSRRHEELLVAYRAPGNPQAIFDIASLDLEPLPVPLVTDFSHREDQHGGPGALLS 360
KRLVDLSRRHEELLVAYRAPGNPQAIFDIASLDLEPLPVPLVTDFSHREDQHGGPGALLS
Sbjct: 301 KRLVDLSRRHEELLVAYRAPGNPQAIFDIASLDLEPLPVPLVTDFSHREDQHGGPGALLS 360
Query: 361 SPKKRPGGASQGGTSEPQGLDAASWAQIHQKLRDFSRSTQSWNGSGHSCWSGPRWLKSNF 420
SPKKRPGGASQGGTSEPQGLDAASWAQIHQKLRDFSRSTQSWNGSGHSCWSGPRWLKSNF
Sbjct: 361 SPKKRPGGASQGGTSEPQGLDAASWAQIHQKLRDFSRSTQSWNGSGHSCWSGPRWLKSNF 420
Query: 421 LSYRSTWTSTWAGTSTKS 438
LSYRSTWTSTWAGTSTKS
Sbjct: 421 LSYRSTWTSTWAGTSTKS 438
>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
isoform alpha [Homo sapiens]
Length = 903
Score = 46.2 bits (108), Expect = 6e-05
Identities = 76/333 (22%), Positives = 122/333 (36%), Gaps = 51/333 (15%)
Query: 77 EQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHP------------RA 124
EQ A + Q + E L E + L L L + + C + E D RA
Sbjct: 295 EQESARLQQRERETLEEERQALTLRLEAE-QQRCCVLQEERDAARAGQLSEHRELETLRA 353
Query: 125 AAQELRHK-AQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQAL 183
A +E R AQ +H +Q ++ E E+ + S + + W +HQ A Q+
Sbjct: 354 ALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEK--SQREAQAAWETQHQLALVQSE 411
Query: 184 VTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEY 243
V R+L+G + AR L + L QA E+ R+QL+ E
Sbjct: 412 V-------RRLEGELDTARRERDALQLEM--------SLVQARYESQRIQLE-----SEL 451
Query: 244 VLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRL 303
++L+ + + A + A + LR L+D+ H +Q+LA + +
Sbjct: 452 AVQLEQRVTERLAQAQESSLRQAAS-LREHHRKQLQDLSGQH---QQELASQLAQFKVEM 507
Query: 304 VDLSRRHEELLVAY--RAPGNPQAIFDIAS--LDLEPLPVPLVTDFSHREDQHGGPGALL 359
+ R +++ Y R + ++ S LE V LV H L
Sbjct: 508 AEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAHWDEANQL 567
Query: 360 SS-------PKKRPGGASQGGTSEPQGLDAASW 385
S P P G S G EP+ + W
Sbjct: 568 LSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 600
>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
isoform beta [Homo sapiens]
Length = 925
Score = 46.2 bits (108), Expect = 6e-05
Identities = 76/333 (22%), Positives = 122/333 (36%), Gaps = 51/333 (15%)
Query: 77 EQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHP------------RA 124
EQ A + Q + E L E + L L L + + C + E D RA
Sbjct: 295 EQESARLQQRERETLEEERQALTLRLEAE-QQRCCVLQEERDAARAGQLSEHRELETLRA 353
Query: 125 AAQELRHK-AQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQAL 183
A +E R AQ +H +Q ++ E E+ + S + + W +HQ A Q+
Sbjct: 354 ALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEK--SQREAQAAWETQHQLALVQSE 411
Query: 184 VTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEY 243
V R+L+G + AR L + L QA E+ R+QL+ E
Sbjct: 412 V-------RRLEGELDTARRERDALQLEM--------SLVQARYESQRIQLE-----SEL 451
Query: 244 VLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRL 303
++L+ + + A + A + LR L+D+ H +Q+LA + +
Sbjct: 452 AVQLEQRVTERLAQAQESSLRQAAS-LREHHRKQLQDLSGQH---QQELASQLAQFKVEM 507
Query: 304 VDLSRRHEELLVAY--RAPGNPQAIFDIAS--LDLEPLPVPLVTDFSHREDQHGGPGALL 359
+ R +++ Y R + ++ S LE V LV H L
Sbjct: 508 AEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAHWDEANQL 567
Query: 360 SS-------PKKRPGGASQGGTSEPQGLDAASW 385
S P P G S G EP+ + W
Sbjct: 568 LSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 600
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 42.0 bits (97), Expect = 0.001
Identities = 78/302 (25%), Positives = 122/302 (40%), Gaps = 59/302 (19%)
Query: 55 KEQQLQ--ISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGC- 111
KEQ+LQ I + +D+Q T E+ + I L+ ++ LE R LE L G+ Q
Sbjct: 264 KEQELQALIQQLSIDLQKVTAETQEKEDV-ITHLQEKVASLEKR-LEQNLSGEEHVQELL 321
Query: 112 -----AVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQ 166
A D R AA+ + KA ++ + R + + + T+ EQ + G+
Sbjct: 322 KEKTLAEQNLEDTRQQLLAARSSQAKAI---NTLETRVR-ELEQTLQASEEQLQQSKGIV 377
Query: 167 GEVKWAL--------EHQEARQQAL------VTRVATLGRQLQGAREEARAAGQRLATQA 212
+ + E +QQAL + R L Q+ A E RAA Q A Q
Sbjct: 378 AAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQIV-ALERTRAADQTTAEQG 436
Query: 213 VVLCSCQGQLRQAEAENARL--------------QLQLKKLKDEYVLR--LQHCAWQAVE 256
+RQ E ENA L Q +LKKLK+E+ R + QA+E
Sbjct: 437 ---------MRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALE 487
Query: 257 HA-----DGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHE 311
+ QA TA+ E L + +EQ++ + R ++ L+ + +
Sbjct: 488 EVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQA 547
Query: 312 EL 313
EL
Sbjct: 548 EL 549
>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
sapiens]
Length = 1551
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/269 (22%), Positives = 101/269 (37%), Gaps = 43/269 (15%)
Query: 56 EQQLQISKELVDIQITTHHLHEQH----EAEIFQLKSEILRLESRVLELELRGDGTSQGC 111
E++LQ ++ ++++ H H E+ QL+ E+ L R+ E+ LR +
Sbjct: 416 ERKLQCLEQ-EKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEM-LRDKASLSQT 473
Query: 112 AVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKW 171
P P QEL HR + + + + ++ G Q E+
Sbjct: 474 DGPPAGSPGQDSDLRQELDRL---------HRELAEGRAGLQAQEQELCRAQGQQEELLQ 524
Query: 172 ALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENAR 231
L+ + R+ A ++ L QL EEARAA R+ EA+ +
Sbjct: 525 RLQEAQEREAATASQTRALSSQL----EEARAA-----------------QRELEAQVSS 563
Query: 232 LQLQLKKLKDEYVLRLQHCAWQAVEH----ADGAGQ---APATTALRTFLEATLEDIRAA 284
L Q+ +L+ ++ RL+ + H +G G P LR + A E + A
Sbjct: 564 LSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQLRKEVAALREQLEQA 623
Query: 285 HRSREQQLARAARSYHKRLVDLSRRHEEL 313
H R A + LSR E L
Sbjct: 624 HSHRPSGKEEALCQLQEENRRLSREQERL 652
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/293 (22%), Positives = 117/293 (39%), Gaps = 33/293 (11%)
Query: 35 GTAVWATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLE 94
G +VW L+ P AL + QQL+ +K Q E+ EAE+ + E E
Sbjct: 700 GGSVWDLPLDTTTPGP-ALEQLQQLEKAKAAKLEQ-------ERREAEMRAKREE----E 747
Query: 95 SRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNP 154
R + ELR Q + + + R +EL + Q ++ +
Sbjct: 748 ERKRQEELR---RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 804
Query: 155 ENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
E Q + + + E + E + +Q+ L+ + + AREE A +RL +
Sbjct: 805 EERQQQEEALRRLEERRREEEERRKQEELLRKQEE--EAAKWAREEEEAQ-RRLEENRLR 861
Query: 215 LCSCQGQLRQAEAENARLQLQLKKLKD---------EYVLRLQH------CAWQAVEHAD 259
+ +LR E E R +L++++ K+ E + RLQ A + +
Sbjct: 862 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 921
Query: 260 GAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEE 312
GQ TTA ++ +L +I+ RE+QL R + L+ ++ ++
Sbjct: 922 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 974
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/293 (22%), Positives = 117/293 (39%), Gaps = 33/293 (11%)
Query: 35 GTAVWATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLE 94
G +VW L+ P AL + QQL+ +K Q E+ EAE+ + E E
Sbjct: 727 GGSVWDLPLDTTTPGP-ALEQLQQLEKAKAAKLEQ-------ERREAEMRAKREE----E 774
Query: 95 SRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNP 154
R + ELR Q + + + R +EL + Q ++ +
Sbjct: 775 ERKRQEELR---RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 831
Query: 155 ENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
E Q + + + E + E + +Q+ L+ + + AREE A +RL +
Sbjct: 832 EERQQQEEALRRLEERRREEEERRKQEELLRKQEE--EAAKWAREEEEAQ-RRLEENRLR 888
Query: 215 LCSCQGQLRQAEAENARLQLQLKKLKD---------EYVLRLQH------CAWQAVEHAD 259
+ +LR E E R +L++++ K+ E + RLQ A + +
Sbjct: 889 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 948
Query: 260 GAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEE 312
GQ TTA ++ +L +I+ RE+QL R + L+ ++ ++
Sbjct: 949 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 1001
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/293 (22%), Positives = 117/293 (39%), Gaps = 33/293 (11%)
Query: 35 GTAVWATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLE 94
G +VW L+ P AL + QQL+ +K Q E+ EAE+ + E E
Sbjct: 706 GGSVWDLPLDTTTPGP-ALEQLQQLEKAKAAKLEQ-------ERREAEMRAKREE----E 753
Query: 95 SRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNP 154
R + ELR Q + + + R +EL + Q ++ +
Sbjct: 754 ERKRQEELR---RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 810
Query: 155 ENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
E Q + + + E + E + +Q+ L+ + + AREE A +RL +
Sbjct: 811 EERQQQEEALRRLEERRREEEERRKQEELLRKQEE--EAAKWAREEEEAQ-RRLEENRLR 867
Query: 215 LCSCQGQLRQAEAENARLQLQLKKLKD---------EYVLRLQH------CAWQAVEHAD 259
+ +LR E E R +L++++ K+ E + RLQ A + +
Sbjct: 868 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
Query: 260 GAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEE 312
GQ TTA ++ +L +I+ RE+QL R + L+ ++ ++
Sbjct: 928 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 980
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/293 (22%), Positives = 117/293 (39%), Gaps = 33/293 (11%)
Query: 35 GTAVWATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLE 94
G +VW L+ P AL + QQL+ +K Q E+ EAE+ + E E
Sbjct: 706 GGSVWDLPLDTTTPGP-ALEQLQQLEKAKAAKLEQ-------ERREAEMRAKREE----E 753
Query: 95 SRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNP 154
R + ELR Q + + + R +EL + Q ++ +
Sbjct: 754 ERKRQEELR---RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 810
Query: 155 ENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
E Q + + + E + E + +Q+ L+ + + AREE A +RL +
Sbjct: 811 EERQQQEEALRRLEERRREEEERRKQEELLRKQEE--EAAKWAREEEEAQ-RRLEENRLR 867
Query: 215 LCSCQGQLRQAEAENARLQLQLKKLKD---------EYVLRLQH------CAWQAVEHAD 259
+ +LR E E R +L++++ K+ E + RLQ A + +
Sbjct: 868 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
Query: 260 GAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEE 312
GQ TTA ++ +L +I+ RE+QL R + L+ ++ ++
Sbjct: 928 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 980
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 40.8 bits (94), Expect = 0.002
Identities = 62/269 (23%), Positives = 110/269 (40%), Gaps = 20/269 (7%)
Query: 53 LNKEQQLQISKELVDIQITTH----HLHEQHEAEIFQLKSEI-LRLESRVLELELRGDGT 107
+ +E+ ++S +Q +T + + EA + +L+ E+ + ++ LE +
Sbjct: 662 MREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM 721
Query: 108 SQGCAVPVESDPRHPRAAAQELRHKA--QVPGHSDDHRFQVQPKNTMNPENEQHRLGSGL 165
+ +E+ + +AA + KA Q+ + R + E RL S L
Sbjct: 722 LEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSL 781
Query: 166 QGEVKWALEH-QEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQ 224
+ + + + Q+ Q+A A L + L +A L S + RQ
Sbjct: 782 EAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQ 841
Query: 225 -AEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRA 283
E E+ R +L K+K+E+ Q +A E + A + L L LE ++
Sbjct: 842 EVEGEHER---RLDKMKEEH----QQVMAKAREQYE-AEERKQRAELLGHLTGELERLQR 893
Query: 284 AHRSREQQLARAARSYHKRLVDLSRRHEE 312
AH E++L + HKRL DL RRH E
Sbjct: 894 AH---ERELETVRQEQHKRLEDLRRRHRE 919
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 40.8 bits (94), Expect = 0.002
Identities = 80/326 (24%), Positives = 122/326 (37%), Gaps = 64/326 (19%)
Query: 75 LHEQHEAEIFQL--KSEILRLESRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHK 132
L + EAE+ L + L+ R LEL R E RH + AQ +
Sbjct: 1084 LQRRQEAELEGLLVRHRDLKANMRALELAHR------------ELQGRHEQLQAQRASVE 1131
Query: 133 AQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGR 192
AQ + + + M + Q GL+ E++ L+ + R Q L+ ++
Sbjct: 1132 AQ------EVALLAERERLMQDGHRQR----GLEEELR-RLQSEHDRAQMLLAELSRERG 1180
Query: 193 QLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAW 252
+LQG R E R RLA + + Q +Q N +L L +L + L Q +
Sbjct: 1181 ELQGERGELRG---RLARLELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSA 1237
Query: 253 QAVEHADGAGQAPA-TTALRTFLEATLEDIRAAHRSREQQL--ARAARSYHKRLVDLSRR 309
Q E+ + A + R LE +LE HR + + L A R ++LV
Sbjct: 1238 QEEENRQLLAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALRREKQKLV----- 1292
Query: 310 HEELLVAYRAPGNPQAIFDIASLDLEPLPVPLVTDFSHRED----------QHGGPGALL 359
E+++ YR LEP+P+P S D + G PG L
Sbjct: 1293 -EKIMDQYRV--------------LEPVPLPRTKKGSWLADKVKRLMRPRREGGPPGGLR 1337
Query: 360 SSPKKRPGGASQGGTSE---PQGLDA 382
S GG E P+G +A
Sbjct: 1338 LGADGAGSTESLGGPPETELPEGREA 1363
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Query: 40 ATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEI--------L 91
A L+ + ++ +E + ++ IQ L + EAEI Q K+ L
Sbjct: 1390 AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1448
Query: 92 RLES--RVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR-HKAQVPGHSDDHRFQVQP 148
R+E RV+ L+L +G A E + + RA A+E K Q ++ R QVQ
Sbjct: 1449 RIEEEIRVVRLQLEATERQRGGA---EGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505
Query: 149 KNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRL 208
++ + E L S ++ E + A E Q A Q R+ Q + A R A
Sbjct: 1506 ESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEELRL-----QAEEAERRLRQAEVER 1559
Query: 209 ATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCA-WQAVEHADGAGQAPA 266
A Q V + +AE ++ R K + E L+ +H A Q E A+ Q A
Sbjct: 1560 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1618
Score = 32.0 bits (71), Expect = 1.1
Identities = 63/271 (23%), Positives = 100/271 (36%), Gaps = 60/271 (22%)
Query: 42 SLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELE 101
S EAE+ A E+ Q+ + L + + L E+ E Q E ELE
Sbjct: 1573 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1632
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
R A + LR + Q + Q K+ E E+ +
Sbjct: 1633 ------------------RWQLKANEALRLRLQAEEVA-------QQKSLAQAEAEKQKE 1667
Query: 162 GSGLQGEVKWALEHQEARQQALVTRVATLGRQL-QGAREEARAAGQRLATQAVVLCSCQG 220
+ + + E Q RQ+ L + RQL +G ++ AA Q L
Sbjct: 1668 EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELI----------- 1716
Query: 221 QLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLED 280
+LR AE E Q ++L +E + RLQ +A A T R LEA L
Sbjct: 1717 RLR-AETEQGE---QQRQLLEEELARLQR-------------EAAAATQKRQELEAELAK 1759
Query: 281 IRA------AHRSREQQLARAARSYHKRLVD 305
+RA A ++R ++ +R+ K+ ++
Sbjct: 1760 VRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790
Score = 30.4 bits (67), Expect = 3.3
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 37/291 (12%)
Query: 43 LEAEVPPDLALNKEQQLQISKELVDIQITTHH-LHEQHEAEIFQLKSEILRLESRVLELE 101
LEA LA +E++ + ++E V + Q +A + E+ RL+++V E
Sbjct: 1967 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL----EEVERLKAKVEEAR 2022
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNT---MNPENEQ 158
+ Q A ++ AQE K ++ H F VQ K + EQ
Sbjct: 2023 RLRERAEQESARQLQ--------LAQEAAQK-RLQAEEKAHAFAVQQKEQELQQTLQQEQ 2073
Query: 159 HRLGSGLQGEVKWAL----EHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
L L+GE + A E +EAR QA A RQ++ A ++A ++ +A
Sbjct: 2074 SVLDQ-LRGEAEAARRAAEEAEEARVQA-EREAAQSRRQVEEAERLKQSAEEQAQARAQA 2131
Query: 215 LCSCQGQLRQAEAENAR------LQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATT 268
+ + ++AE E AR L+ K+ D + + + A Q + Q T
Sbjct: 2132 QAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ--ELT 2189
Query: 269 ALRTFLEAT------LEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEEL 313
LR LE T L++ ++ + AR + L + + EEL
Sbjct: 2190 TLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2240
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Query: 40 ATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEI--------L 91
A L+ + ++ +E + ++ IQ L + EAEI Q K+ L
Sbjct: 1394 AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1452
Query: 92 RLES--RVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR-HKAQVPGHSDDHRFQVQP 148
R+E RV+ L+L +G A E + + RA A+E K Q ++ R QVQ
Sbjct: 1453 RIEEEIRVVRLQLEATERQRGGA---EGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1509
Query: 149 KNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRL 208
++ + E L S ++ E + A E Q A Q R+ Q + A R A
Sbjct: 1510 ESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEELRL-----QAEEAERRLRQAEVER 1563
Query: 209 ATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCA-WQAVEHADGAGQAPA 266
A Q V + +AE ++ R K + E L+ +H A Q E A+ Q A
Sbjct: 1564 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1622
Score = 32.0 bits (71), Expect = 1.1
Identities = 63/271 (23%), Positives = 100/271 (36%), Gaps = 60/271 (22%)
Query: 42 SLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELE 101
S EAE+ A E+ Q+ + L + + L E+ E Q E ELE
Sbjct: 1577 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1636
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
R A + LR + Q + Q K+ E E+ +
Sbjct: 1637 ------------------RWQLKANEALRLRLQAEEVA-------QQKSLAQAEAEKQKE 1671
Query: 162 GSGLQGEVKWALEHQEARQQALVTRVATLGRQL-QGAREEARAAGQRLATQAVVLCSCQG 220
+ + + E Q RQ+ L + RQL +G ++ AA Q L
Sbjct: 1672 EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELI----------- 1720
Query: 221 QLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLED 280
+LR AE E Q ++L +E + RLQ +A A T R LEA L
Sbjct: 1721 RLR-AETEQGE---QQRQLLEEELARLQR-------------EAAAATQKRQELEAELAK 1763
Query: 281 IRA------AHRSREQQLARAARSYHKRLVD 305
+RA A ++R ++ +R+ K+ ++
Sbjct: 1764 VRAEMEVLLASKARAEEESRSTSEKSKQRLE 1794
Score = 30.4 bits (67), Expect = 3.3
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 37/291 (12%)
Query: 43 LEAEVPPDLALNKEQQLQISKELVDIQITTHH-LHEQHEAEIFQLKSEILRLESRVLELE 101
LEA LA +E++ + ++E V + Q +A + E+ RL+++V E
Sbjct: 1971 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL----EEVERLKAKVEEAR 2026
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNT---MNPENEQ 158
+ Q A ++ AQE K ++ H F VQ K + EQ
Sbjct: 2027 RLRERAEQESARQLQ--------LAQEAAQK-RLQAEEKAHAFAVQQKEQELQQTLQQEQ 2077
Query: 159 HRLGSGLQGEVKWAL----EHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
L L+GE + A E +EAR QA A RQ++ A ++A ++ +A
Sbjct: 2078 SVLDQ-LRGEAEAARRAAEEAEEARVQA-EREAAQSRRQVEEAERLKQSAEEQAQARAQA 2135
Query: 215 LCSCQGQLRQAEAENAR------LQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATT 268
+ + ++AE E AR L+ K+ D + + + A Q + Q T
Sbjct: 2136 QAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ--ELT 2193
Query: 269 ALRTFLEAT------LEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEEL 313
LR LE T L++ ++ + AR + L + + EEL
Sbjct: 2194 TLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2244
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Query: 40 ATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEI--------L 91
A L+ + ++ +E + ++ IQ L + EAEI Q K+ L
Sbjct: 1390 AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1448
Query: 92 RLES--RVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR-HKAQVPGHSDDHRFQVQP 148
R+E RV+ L+L +G A E + + RA A+E K Q ++ R QVQ
Sbjct: 1449 RIEEEIRVVRLQLEATERQRGGA---EGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505
Query: 149 KNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRL 208
++ + E L S ++ E + A E Q A Q R+ Q + A R A
Sbjct: 1506 ESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEELRL-----QAEEAERRLRQAEVER 1559
Query: 209 ATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCA-WQAVEHADGAGQAPA 266
A Q V + +AE ++ R K + E L+ +H A Q E A+ Q A
Sbjct: 1560 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1618
Score = 32.0 bits (71), Expect = 1.1
Identities = 63/271 (23%), Positives = 100/271 (36%), Gaps = 60/271 (22%)
Query: 42 SLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELE 101
S EAE+ A E+ Q+ + L + + L E+ E Q E ELE
Sbjct: 1573 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1632
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
R A + LR + Q + Q K+ E E+ +
Sbjct: 1633 ------------------RWQLKANEALRLRLQAEEVA-------QQKSLAQAEAEKQKE 1667
Query: 162 GSGLQGEVKWALEHQEARQQALVTRVATLGRQL-QGAREEARAAGQRLATQAVVLCSCQG 220
+ + + E Q RQ+ L + RQL +G ++ AA Q L
Sbjct: 1668 EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELI----------- 1716
Query: 221 QLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLED 280
+LR AE E Q ++L +E + RLQ +A A T R LEA L
Sbjct: 1717 RLR-AETEQGE---QQRQLLEEELARLQR-------------EAAAATQKRQELEAELAK 1759
Query: 281 IRA------AHRSREQQLARAARSYHKRLVD 305
+RA A ++R ++ +R+ K+ ++
Sbjct: 1760 VRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790
Score = 30.4 bits (67), Expect = 3.3
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 37/291 (12%)
Query: 43 LEAEVPPDLALNKEQQLQISKELVDIQITTHH-LHEQHEAEIFQLKSEILRLESRVLELE 101
LEA LA +E++ + ++E V + Q +A + E+ RL+++V E
Sbjct: 1967 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL----EEVERLKAKVEEAR 2022
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNT---MNPENEQ 158
+ Q A ++ AQE K ++ H F VQ K + EQ
Sbjct: 2023 RLRERAEQESARQLQ--------LAQEAAQK-RLQAEEKAHAFAVQQKEQELQQTLQQEQ 2073
Query: 159 HRLGSGLQGEVKWAL----EHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
L L+GE + A E +EAR QA A RQ++ A ++A ++ +A
Sbjct: 2074 SVLDQ-LRGEAEAARRAAEEAEEARVQA-EREAAQSRRQVEEAERLKQSAEEQAQARAQA 2131
Query: 215 LCSCQGQLRQAEAENAR------LQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATT 268
+ + ++AE E AR L+ K+ D + + + A Q + Q T
Sbjct: 2132 QAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ--ELT 2189
Query: 269 ALRTFLEAT------LEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEEL 313
LR LE T L++ ++ + AR + L + + EEL
Sbjct: 2190 TLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2240
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Query: 40 ATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEI--------L 91
A L+ + ++ +E + ++ IQ L + EAEI Q K+ L
Sbjct: 1358 AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1416
Query: 92 RLES--RVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR-HKAQVPGHSDDHRFQVQP 148
R+E RV+ L+L +G A E + + RA A+E K Q ++ R QVQ
Sbjct: 1417 RIEEEIRVVRLQLEATERQRGGA---EGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1473
Query: 149 KNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRL 208
++ + E L S ++ E + A E Q A Q R+ Q + A R A
Sbjct: 1474 ESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEELRL-----QAEEAERRLRQAEVER 1527
Query: 209 ATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCA-WQAVEHADGAGQAPA 266
A Q V + +AE ++ R K + E L+ +H A Q E A+ Q A
Sbjct: 1528 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1586
Score = 32.0 bits (71), Expect = 1.1
Identities = 63/271 (23%), Positives = 100/271 (36%), Gaps = 60/271 (22%)
Query: 42 SLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELE 101
S EAE+ A E+ Q+ + L + + L E+ E Q E ELE
Sbjct: 1541 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1600
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
R A + LR + Q + Q K+ E E+ +
Sbjct: 1601 ------------------RWQLKANEALRLRLQAEEVA-------QQKSLAQAEAEKQKE 1635
Query: 162 GSGLQGEVKWALEHQEARQQALVTRVATLGRQL-QGAREEARAAGQRLATQAVVLCSCQG 220
+ + + E Q RQ+ L + RQL +G ++ AA Q L
Sbjct: 1636 EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELI----------- 1684
Query: 221 QLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLED 280
+LR AE E Q ++L +E + RLQ +A A T R LEA L
Sbjct: 1685 RLR-AETEQGE---QQRQLLEEELARLQR-------------EAAAATQKRQELEAELAK 1727
Query: 281 IRA------AHRSREQQLARAARSYHKRLVD 305
+RA A ++R ++ +R+ K+ ++
Sbjct: 1728 VRAEMEVLLASKARAEEESRSTSEKSKQRLE 1758
Score = 30.4 bits (67), Expect = 3.3
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 37/291 (12%)
Query: 43 LEAEVPPDLALNKEQQLQISKELVDIQITTHH-LHEQHEAEIFQLKSEILRLESRVLELE 101
LEA LA +E++ + ++E V + Q +A + E+ RL+++V E
Sbjct: 1935 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL----EEVERLKAKVEEAR 1990
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNT---MNPENEQ 158
+ Q A ++ AQE K ++ H F VQ K + EQ
Sbjct: 1991 RLRERAEQESARQLQ--------LAQEAAQK-RLQAEEKAHAFAVQQKEQELQQTLQQEQ 2041
Query: 159 HRLGSGLQGEVKWAL----EHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
L L+GE + A E +EAR QA A RQ++ A ++A ++ +A
Sbjct: 2042 SVLDQ-LRGEAEAARRAAEEAEEARVQA-EREAAQSRRQVEEAERLKQSAEEQAQARAQA 2099
Query: 215 LCSCQGQLRQAEAENAR------LQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATT 268
+ + ++AE E AR L+ K+ D + + + A Q + Q T
Sbjct: 2100 QAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ--ELT 2157
Query: 269 ALRTFLEAT------LEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEEL 313
LR LE T L++ ++ + AR + L + + EEL
Sbjct: 2158 TLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2208
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Query: 40 ATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEI--------L 91
A L+ + ++ +E + ++ IQ L + EAEI Q K+ L
Sbjct: 1527 AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1585
Query: 92 RLES--RVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR-HKAQVPGHSDDHRFQVQP 148
R+E RV+ L+L +G A E + + RA A+E K Q ++ R QVQ
Sbjct: 1586 RIEEEIRVVRLQLEATERQRGGA---EGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1642
Query: 149 KNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRL 208
++ + E L S ++ E + A E Q A Q R+ Q + A R A
Sbjct: 1643 ESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEELRL-----QAEEAERRLRQAEVER 1696
Query: 209 ATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCA-WQAVEHADGAGQAPA 266
A Q V + +AE ++ R K + E L+ +H A Q E A+ Q A
Sbjct: 1697 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1755
Score = 32.0 bits (71), Expect = 1.1
Identities = 63/271 (23%), Positives = 100/271 (36%), Gaps = 60/271 (22%)
Query: 42 SLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELE 101
S EAE+ A E+ Q+ + L + + L E+ E Q E ELE
Sbjct: 1710 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1769
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
R A + LR + Q + Q K+ E E+ +
Sbjct: 1770 ------------------RWQLKANEALRLRLQAEEVA-------QQKSLAQAEAEKQKE 1804
Query: 162 GSGLQGEVKWALEHQEARQQALVTRVATLGRQL-QGAREEARAAGQRLATQAVVLCSCQG 220
+ + + E Q RQ+ L + RQL +G ++ AA Q L
Sbjct: 1805 EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELI----------- 1853
Query: 221 QLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLED 280
+LR AE E Q ++L +E + RLQ +A A T R LEA L
Sbjct: 1854 RLR-AETEQGE---QQRQLLEEELARLQR-------------EAAAATQKRQELEAELAK 1896
Query: 281 IRA------AHRSREQQLARAARSYHKRLVD 305
+RA A ++R ++ +R+ K+ ++
Sbjct: 1897 VRAEMEVLLASKARAEEESRSTSEKSKQRLE 1927
Score = 30.4 bits (67), Expect = 3.3
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 37/291 (12%)
Query: 43 LEAEVPPDLALNKEQQLQISKELVDIQITTHH-LHEQHEAEIFQLKSEILRLESRVLELE 101
LEA LA +E++ + ++E V + Q +A + E+ RL+++V E
Sbjct: 2104 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL----EEVERLKAKVEEAR 2159
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNT---MNPENEQ 158
+ Q A ++ AQE K ++ H F VQ K + EQ
Sbjct: 2160 RLRERAEQESARQLQ--------LAQEAAQK-RLQAEEKAHAFAVQQKEQELQQTLQQEQ 2210
Query: 159 HRLGSGLQGEVKWAL----EHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
L L+GE + A E +EAR QA A RQ++ A ++A ++ +A
Sbjct: 2211 SVLDQ-LRGEAEAARRAAEEAEEARVQA-EREAAQSRRQVEEAERLKQSAEEQAQARAQA 2268
Query: 215 LCSCQGQLRQAEAENAR------LQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATT 268
+ + ++AE E AR L+ K+ D + + + A Q + Q T
Sbjct: 2269 QAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ--ELT 2326
Query: 269 ALRTFLEAT------LEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEEL 313
LR LE T L++ ++ + AR + L + + EEL
Sbjct: 2327 TLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2377
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Query: 40 ATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEI--------L 91
A L+ + ++ +E + ++ IQ L + EAEI Q K+ L
Sbjct: 1368 AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1426
Query: 92 RLES--RVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR-HKAQVPGHSDDHRFQVQP 148
R+E RV+ L+L +G A E + + RA A+E K Q ++ R QVQ
Sbjct: 1427 RIEEEIRVVRLQLEATERQRGGA---EGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1483
Query: 149 KNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRL 208
++ + E L S ++ E + A E Q A Q R+ Q + A R A
Sbjct: 1484 ESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEELRL-----QAEEAERRLRQAEVER 1537
Query: 209 ATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCA-WQAVEHADGAGQAPA 266
A Q V + +AE ++ R K + E L+ +H A Q E A+ Q A
Sbjct: 1538 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1596
Score = 32.0 bits (71), Expect = 1.1
Identities = 63/271 (23%), Positives = 100/271 (36%), Gaps = 60/271 (22%)
Query: 42 SLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELE 101
S EAE+ A E+ Q+ + L + + L E+ E Q E ELE
Sbjct: 1551 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1610
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
R A + LR + Q + Q K+ E E+ +
Sbjct: 1611 ------------------RWQLKANEALRLRLQAEEVA-------QQKSLAQAEAEKQKE 1645
Query: 162 GSGLQGEVKWALEHQEARQQALVTRVATLGRQL-QGAREEARAAGQRLATQAVVLCSCQG 220
+ + + E Q RQ+ L + RQL +G ++ AA Q L
Sbjct: 1646 EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELI----------- 1694
Query: 221 QLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLED 280
+LR AE E Q ++L +E + RLQ +A A T R LEA L
Sbjct: 1695 RLR-AETEQGE---QQRQLLEEELARLQR-------------EAAAATQKRQELEAELAK 1737
Query: 281 IRA------AHRSREQQLARAARSYHKRLVD 305
+RA A ++R ++ +R+ K+ ++
Sbjct: 1738 VRAEMEVLLASKARAEEESRSTSEKSKQRLE 1768
Score = 30.4 bits (67), Expect = 3.3
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 37/291 (12%)
Query: 43 LEAEVPPDLALNKEQQLQISKELVDIQITTHH-LHEQHEAEIFQLKSEILRLESRVLELE 101
LEA LA +E++ + ++E V + Q +A + E+ RL+++V E
Sbjct: 1945 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL----EEVERLKAKVEEAR 2000
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNT---MNPENEQ 158
+ Q A ++ AQE K ++ H F VQ K + EQ
Sbjct: 2001 RLRERAEQESARQLQ--------LAQEAAQK-RLQAEEKAHAFAVQQKEQELQQTLQQEQ 2051
Query: 159 HRLGSGLQGEVKWAL----EHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
L L+GE + A E +EAR QA A RQ++ A ++A ++ +A
Sbjct: 2052 SVLDQ-LRGEAEAARRAAEEAEEARVQA-EREAAQSRRQVEEAERLKQSAEEQAQARAQA 2109
Query: 215 LCSCQGQLRQAEAENAR------LQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATT 268
+ + ++AE E AR L+ K+ D + + + A Q + Q T
Sbjct: 2110 QAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ--ELT 2167
Query: 269 ALRTFLEAT------LEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEEL 313
LR LE T L++ ++ + AR + L + + EEL
Sbjct: 2168 TLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2218
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Query: 40 ATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEI--------L 91
A L+ + ++ +E + ++ IQ L + EAEI Q K+ L
Sbjct: 1376 AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1434
Query: 92 RLES--RVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR-HKAQVPGHSDDHRFQVQP 148
R+E RV+ L+L +G A E + + RA A+E K Q ++ R QVQ
Sbjct: 1435 RIEEEIRVVRLQLEATERQRGGA---EGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1491
Query: 149 KNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRL 208
++ + E L S ++ E + A E Q A Q R+ Q + A R A
Sbjct: 1492 ESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEELRL-----QAEEAERRLRQAEVER 1545
Query: 209 ATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCA-WQAVEHADGAGQAPA 266
A Q V + +AE ++ R K + E L+ +H A Q E A+ Q A
Sbjct: 1546 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1604
Score = 32.0 bits (71), Expect = 1.1
Identities = 63/271 (23%), Positives = 100/271 (36%), Gaps = 60/271 (22%)
Query: 42 SLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELE 101
S EAE+ A E+ Q+ + L + + L E+ E Q E ELE
Sbjct: 1559 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1618
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
R A + LR + Q + Q K+ E E+ +
Sbjct: 1619 ------------------RWQLKANEALRLRLQAEEVA-------QQKSLAQAEAEKQKE 1653
Query: 162 GSGLQGEVKWALEHQEARQQALVTRVATLGRQL-QGAREEARAAGQRLATQAVVLCSCQG 220
+ + + E Q RQ+ L + RQL +G ++ AA Q L
Sbjct: 1654 EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELI----------- 1702
Query: 221 QLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLED 280
+LR AE E Q ++L +E + RLQ +A A T R LEA L
Sbjct: 1703 RLR-AETEQGE---QQRQLLEEELARLQR-------------EAAAATQKRQELEAELAK 1745
Query: 281 IRA------AHRSREQQLARAARSYHKRLVD 305
+RA A ++R ++ +R+ K+ ++
Sbjct: 1746 VRAEMEVLLASKARAEEESRSTSEKSKQRLE 1776
Score = 30.4 bits (67), Expect = 3.3
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 37/291 (12%)
Query: 43 LEAEVPPDLALNKEQQLQISKELVDIQITTHH-LHEQHEAEIFQLKSEILRLESRVLELE 101
LEA LA +E++ + ++E V + Q +A + E+ RL+++V E
Sbjct: 1953 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL----EEVERLKAKVEEAR 2008
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNT---MNPENEQ 158
+ Q A ++ AQE K ++ H F VQ K + EQ
Sbjct: 2009 RLRERAEQESARQLQ--------LAQEAAQK-RLQAEEKAHAFAVQQKEQELQQTLQQEQ 2059
Query: 159 HRLGSGLQGEVKWAL----EHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
L L+GE + A E +EAR QA A RQ++ A ++A ++ +A
Sbjct: 2060 SVLDQ-LRGEAEAARRAAEEAEEARVQA-EREAAQSRRQVEEAERLKQSAEEQAQARAQA 2117
Query: 215 LCSCQGQLRQAEAENAR------LQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATT 268
+ + ++AE E AR L+ K+ D + + + A Q + Q T
Sbjct: 2118 QAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ--ELT 2175
Query: 269 ALRTFLEAT------LEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEEL 313
LR LE T L++ ++ + AR + L + + EEL
Sbjct: 2176 TLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2226
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 39.7 bits (91), Expect = 0.005
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Query: 40 ATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEI--------L 91
A L+ + ++ +E + ++ IQ L + EAEI Q K+ L
Sbjct: 1417 AKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1475
Query: 92 RLES--RVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR-HKAQVPGHSDDHRFQVQP 148
R+E RV+ L+L +G A E + + RA A+E K Q ++ R QVQ
Sbjct: 1476 RIEEEIRVVRLQLEATERQRGGA---EGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1532
Query: 149 KNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRL 208
++ + E L S ++ E + A E Q A Q R+ Q + A R A
Sbjct: 1533 ESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEELRL-----QAEEAERRLRQAEVER 1586
Query: 209 ATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCA-WQAVEHADGAGQAPA 266
A Q V + +AE ++ R K + E L+ +H A Q E A+ Q A
Sbjct: 1587 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1645
Score = 32.0 bits (71), Expect = 1.1
Identities = 63/271 (23%), Positives = 100/271 (36%), Gaps = 60/271 (22%)
Query: 42 SLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELE 101
S EAE+ A E+ Q+ + L + + L E+ E Q E ELE
Sbjct: 1600 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1659
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
R A + LR + Q + Q K+ E E+ +
Sbjct: 1660 ------------------RWQLKANEALRLRLQAEEVA-------QQKSLAQAEAEKQKE 1694
Query: 162 GSGLQGEVKWALEHQEARQQALVTRVATLGRQL-QGAREEARAAGQRLATQAVVLCSCQG 220
+ + + E Q RQ+ L + RQL +G ++ AA Q L
Sbjct: 1695 EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELI----------- 1743
Query: 221 QLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLED 280
+LR AE E Q ++L +E + RLQ +A A T R LEA L
Sbjct: 1744 RLR-AETEQGE---QQRQLLEEELARLQR-------------EAAAATQKRQELEAELAK 1786
Query: 281 IRA------AHRSREQQLARAARSYHKRLVD 305
+RA A ++R ++ +R+ K+ ++
Sbjct: 1787 VRAEMEVLLASKARAEEESRSTSEKSKQRLE 1817
Score = 30.4 bits (67), Expect = 3.3
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 37/291 (12%)
Query: 43 LEAEVPPDLALNKEQQLQISKELVDIQITTHH-LHEQHEAEIFQLKSEILRLESRVLELE 101
LEA LA +E++ + ++E V + Q +A + E+ RL+++V E
Sbjct: 1994 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL----EEVERLKAKVEEAR 2049
Query: 102 LRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNT---MNPENEQ 158
+ Q A ++ AQE K ++ H F VQ K + EQ
Sbjct: 2050 RLRERAEQESARQLQ--------LAQEAAQK-RLQAEEKAHAFAVQQKEQELQQTLQQEQ 2100
Query: 159 HRLGSGLQGEVKWAL----EHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVV 214
L L+GE + A E +EAR QA A RQ++ A ++A ++ +A
Sbjct: 2101 SVLDQ-LRGEAEAARRAAEEAEEARVQA-EREAAQSRRQVEEAERLKQSAEEQAQARAQA 2158
Query: 215 LCSCQGQLRQAEAENAR------LQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATT 268
+ + ++AE E AR L+ K+ D + + + A Q + Q T
Sbjct: 2159 QAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ--ELT 2216
Query: 269 ALRTFLEAT------LEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEEL 313
LR LE T L++ ++ + AR + L + + EEL
Sbjct: 2217 TLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2267
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 38.5 bits (88), Expect = 0.012
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 15/135 (11%)
Query: 75 LHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQ 134
LHE A + KS I LE+++ +LE + VE + R +AA + L+ K +
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQ-----------VEQEAREKQAATKSLKQKDK 1849
Query: 135 VPGHSDDHRFQVQPKNTMNPE-NEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQ 193
+ QV+ + M + EQ G+ ++K LE E Q + L R+
Sbjct: 1850 ---KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Query: 194 LQGAREEARAAGQRL 208
L A E A G+ +
Sbjct: 1907 LDEATESNEAMGREV 1921
Score = 33.1 bits (74), Expect = 0.51
Identities = 57/281 (20%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 50 DLALNKEQQLQISKELVDIQITTHH-----LHEQHEAEIFQLKSEILRLESRVLELELRG 104
+L +EQ++ + K+ +D + +H + ++H + +L ++ + + L+ +
Sbjct: 1167 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD-KN 1225
Query: 105 DGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSG 164
T + + + R A QE+ HK + QVQ + + E+ R
Sbjct: 1226 KQTLEKENADLAGELRVLGQAKQEVEHKKK------KLEAQVQELQSKCSDGERARAELN 1279
Query: 165 -----LQGEVKWA---LEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLC 216
LQ EV+ L E + L VA+L QLQ +E L +
Sbjct: 1280 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE-------LLQEETRQKL 1332
Query: 217 SCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEA 276
+ +LRQ E E LQ QL + + +H + ++ +D +
Sbjct: 1333 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS--------------KK 1378
Query: 277 TLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEELLVAY 317
L+D S + L + + K + +L++++EE AY
Sbjct: 1379 KLQDFA----STVEALEEGKKRFQKEIENLTQQYEEKAAAY 1415
Score = 28.9 bits (63), Expect = 9.6
Identities = 37/181 (20%), Positives = 72/181 (39%), Gaps = 25/181 (13%)
Query: 86 LKSEILRLESRVLELELRGD---GTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDH 142
L+ E RLE+R+ +LE + G + + V + + EL + ++
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1786
Query: 143 RFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAR---- 198
R Q++ +N ++ H + ++ + K + EA+ L +V R+ Q A
Sbjct: 1787 RQQLERQNK-ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 199 -------------EEARAAGQRLATQA----VVLCSCQGQLRQAEAENARLQLQLKKLKD 241
E+ R ++ QA + + QL +AE E+ R+ +KL+
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905
Query: 242 E 242
E
Sbjct: 1906 E 1906
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 38.5 bits (88), Expect = 0.012
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 15/135 (11%)
Query: 75 LHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQ 134
LHE A + KS I LE+++ +LE + VE + R +AA + L+ K +
Sbjct: 1808 LHEMEGAVKSKFKSTIAALEAKIAQLEEQ-----------VEQEAREKQAATKSLKQKDK 1856
Query: 135 VPGHSDDHRFQVQPKNTMNPE-NEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQ 193
+ QV+ + M + EQ G+ ++K LE E Q + L R+
Sbjct: 1857 ---KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913
Query: 194 LQGAREEARAAGQRL 208
L A E A G+ +
Sbjct: 1914 LDEATESNEAMGREV 1928
Score = 33.1 bits (74), Expect = 0.51
Identities = 57/281 (20%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 50 DLALNKEQQLQISKELVDIQITTHH-----LHEQHEAEIFQLKSEILRLESRVLELELRG 104
+L +EQ++ + K+ +D + +H + ++H + +L ++ + + L+ +
Sbjct: 1174 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD-KN 1232
Query: 105 DGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSG 164
T + + + R A QE+ HK + QVQ + + E+ R
Sbjct: 1233 KQTLEKENADLAGELRVLGQAKQEVEHKKK------KLEAQVQELQSKCSDGERARAELN 1286
Query: 165 -----LQGEVKWA---LEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLC 216
LQ EV+ L E + L VA+L QLQ +E L +
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE-------LLQEETRQKL 1339
Query: 217 SCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEA 276
+ +LRQ E E LQ QL + + +H + ++ +D +
Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS--------------KK 1385
Query: 277 TLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEELLVAY 317
L+D S + L + + K + +L++++EE AY
Sbjct: 1386 KLQDFA----STVEALEEGKKRFQKEIENLTQQYEEKAAAY 1422
Score = 28.9 bits (63), Expect = 9.6
Identities = 37/181 (20%), Positives = 72/181 (39%), Gaps = 25/181 (13%)
Query: 86 LKSEILRLESRVLELELRGD---GTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDH 142
L+ E RLE+R+ +LE + G + + V + + EL + ++
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1793
Query: 143 RFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAR---- 198
R Q++ +N ++ H + ++ + K + EA+ L +V R+ Q A
Sbjct: 1794 RQQLERQNK-ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 199 -------------EEARAAGQRLATQA----VVLCSCQGQLRQAEAENARLQLQLKKLKD 241
E+ R ++ QA + + QL +AE E+ R+ +KL+
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1912
Query: 242 E 242
E
Sbjct: 1913 E 1913
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 38.5 bits (88), Expect = 0.012
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 15/135 (11%)
Query: 75 LHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQ 134
LHE A + KS I LE+++ +LE + VE + R +AA + L+ K +
Sbjct: 1808 LHEMEGAVKSKFKSTIAALEAKIAQLEEQ-----------VEQEAREKQAATKSLKQKDK 1856
Query: 135 VPGHSDDHRFQVQPKNTMNPE-NEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQ 193
+ QV+ + M + EQ G+ ++K LE E Q + L R+
Sbjct: 1857 ---KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913
Query: 194 LQGAREEARAAGQRL 208
L A E A G+ +
Sbjct: 1914 LDEATESNEAMGREV 1928
Score = 33.1 bits (74), Expect = 0.51
Identities = 57/281 (20%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 50 DLALNKEQQLQISKELVDIQITTHH-----LHEQHEAEIFQLKSEILRLESRVLELELRG 104
+L +EQ++ + K+ +D + +H + ++H + +L ++ + + L+ +
Sbjct: 1174 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD-KN 1232
Query: 105 DGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSG 164
T + + + R A QE+ HK + QVQ + + E+ R
Sbjct: 1233 KQTLEKENADLAGELRVLGQAKQEVEHKKK------KLEAQVQELQSKCSDGERARAELN 1286
Query: 165 -----LQGEVKWA---LEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLC 216
LQ EV+ L E + L VA+L QLQ +E L +
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE-------LLQEETRQKL 1339
Query: 217 SCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEA 276
+ +LRQ E E LQ QL + + +H + ++ +D +
Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS--------------KK 1385
Query: 277 TLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEELLVAY 317
L+D S + L + + K + +L++++EE AY
Sbjct: 1386 KLQDFA----STVEALEEGKKRFQKEIENLTQQYEEKAAAY 1422
Score = 28.9 bits (63), Expect = 9.6
Identities = 37/181 (20%), Positives = 72/181 (39%), Gaps = 25/181 (13%)
Query: 86 LKSEILRLESRVLELELRGD---GTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDH 142
L+ E RLE+R+ +LE + G + + V + + EL + ++
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1793
Query: 143 RFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAR---- 198
R Q++ +N ++ H + ++ + K + EA+ L +V R+ Q A
Sbjct: 1794 RQQLERQNK-ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 199 -------------EEARAAGQRLATQA----VVLCSCQGQLRQAEAENARLQLQLKKLKD 241
E+ R ++ QA + + QL +AE E+ R+ +KL+
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1912
Query: 242 E 242
E
Sbjct: 1913 E 1913
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 38.5 bits (88), Expect = 0.012
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 15/135 (11%)
Query: 75 LHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQ 134
LHE A + KS I LE+++ +LE + VE + R +AA + L+ K +
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQ-----------VEQEAREKQAATKSLKQKDK 1849
Query: 135 VPGHSDDHRFQVQPKNTMNPE-NEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQ 193
+ QV+ + M + EQ G+ ++K LE E Q + L R+
Sbjct: 1850 ---KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Query: 194 LQGAREEARAAGQRL 208
L A E A G+ +
Sbjct: 1907 LDEATESNEAMGREV 1921
Score = 33.1 bits (74), Expect = 0.51
Identities = 57/281 (20%), Positives = 110/281 (39%), Gaps = 45/281 (16%)
Query: 50 DLALNKEQQLQISKELVDIQITTHH-----LHEQHEAEIFQLKSEILRLESRVLELELRG 104
+L +EQ++ + K+ +D + +H + ++H + +L ++ + + L+ +
Sbjct: 1167 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD-KN 1225
Query: 105 DGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSG 164
T + + + R A QE+ HK + QVQ + + E+ R
Sbjct: 1226 KQTLEKENADLAGELRVLGQAKQEVEHKKK------KLEAQVQELQSKCSDGERARAELN 1279
Query: 165 -----LQGEVKWA---LEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLC 216
LQ EV+ L E + L VA+L QLQ +E L +
Sbjct: 1280 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE-------LLQEETRQKL 1332
Query: 217 SCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEA 276
+ +LRQ E E LQ QL + + +H + ++ +D +
Sbjct: 1333 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS--------------KK 1378
Query: 277 TLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEELLVAY 317
L+D S + L + + K + +L++++EE AY
Sbjct: 1379 KLQDFA----STVEALEEGKKRFQKEIENLTQQYEEKAAAY 1415
Score = 28.9 bits (63), Expect = 9.6
Identities = 37/181 (20%), Positives = 72/181 (39%), Gaps = 25/181 (13%)
Query: 86 LKSEILRLESRVLELELRGD---GTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDH 142
L+ E RLE+R+ +LE + G + + V + + EL + ++
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1786
Query: 143 RFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAR---- 198
R Q++ +N ++ H + ++ + K + EA+ L +V R+ Q A
Sbjct: 1787 RQQLERQNK-ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 199 -------------EEARAAGQRLATQA----VVLCSCQGQLRQAEAENARLQLQLKKLKD 241
E+ R ++ QA + + QL +AE E+ R+ +KL+
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905
Query: 242 E 242
E
Sbjct: 1906 E 1906
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 38.1 bits (87), Expect = 0.016
Identities = 71/310 (22%), Positives = 117/310 (37%), Gaps = 29/310 (9%)
Query: 24 RAKDWLPGAPGGTAVWATSLE------AEVPPDLALNKE----QQLQISKELVDIQITTH 73
R K+ L G AV + E +E L L KE ++ ++L ++
Sbjct: 869 REKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 928
Query: 74 HLHEQHEAEIFQ---LKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELR 130
L + +A + L E+ L +++ + + + A + R +A+ +E R
Sbjct: 929 QLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQR 988
Query: 131 HKAQVPGHSDD-HRFQVQPKNTMNP-ENEQHRLGSGLQGEVKWALEHQEARQQALVTRVA 188
H +D R Q + + E E+ +L S LQ E + L EA ++ L +A
Sbjct: 989 -----AAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIA 1043
Query: 189 TLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQ 248
L Q R+E + QA+ L + + R L L+ E R
Sbjct: 1044 AL----QQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDA 1099
Query: 249 HCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSR 308
Q+ + D + T+ LR L A E+ AAH ++L AR K+ R
Sbjct: 1100 ----QSRQEQDRSTVNALTSELRD-LRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLR 1154
Query: 309 RHEELLVAYR 318
EEL R
Sbjct: 1155 EAEELRTQLR 1164
Score = 36.6 bits (83), Expect = 0.046
Identities = 68/291 (23%), Positives = 118/291 (40%), Gaps = 37/291 (12%)
Query: 52 ALNKEQQLQISKELVDIQITT--HHLH-EQHEAEIFQLKSEILRLESRVLELELRGDGTS 108
A + Q+L+ + EL+ + + H L Q +AE +L+ E +L++ EL + D
Sbjct: 587 AQREVQRLRSANELLSREKSNLAHSLQVAQQQAE--ELRQEREKLQAAQEELRRQRDRLE 644
Query: 109 QGCAVPVESDPRHPRAAAQELRHKAQVPG-HSDDHRFQVQPKNTMNPENEQHRLGSGLQG 167
+ V+ R R + R Q+ G S + V+ + ++ Q + +
Sbjct: 645 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 704
Query: 168 EVKWALEHQEARQQAL---VTRVATLGRQLQGAREEARAAGQRLATQAVVL--------- 215
EV AL EA + L +T++ LQ + + A + LA + L
Sbjct: 705 EVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEE 764
Query: 216 --CSCQGQLRQAEAE------------NARLQLQLKKLKDEYVLRLQHCAWQAVEHADGA 261
+ QG+ RQAE E RL+ ++ + E LR+ A +A+E
Sbjct: 765 EKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQ---- 820
Query: 262 GQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEE 312
Q P R+ L+ L + REQ+L +A R +++ L R E
Sbjct: 821 -QLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 870
Score = 33.9 bits (76), Expect = 0.30
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 10/90 (11%)
Query: 157 EQHRLGSGLQGEVKWALEHQEARQQALVT----------RVATLGRQLQGAREEARAAGQ 206
EQ GL+G ++ A + QEA +Q L T ++A L RQL G +E A +
Sbjct: 796 EQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 855
Query: 207 RLATQAVVLCSCQGQLRQAEAENARLQLQL 236
Q L + E+A L +QL
Sbjct: 856 EAQRQVEALERAAREKEALAKEHAGLAVQL 885
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 37.4 bits (85), Expect = 0.027
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 21/188 (11%)
Query: 62 SKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRH 121
+ ++V++Q L E+ E+ Q+K + L SRV E+E + + E + ++
Sbjct: 267 TSQIVELQ----ELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKY 322
Query: 122 PRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQ 181
R + + K + + R K ++ + E + ++ LE++ A ++
Sbjct: 323 QRDIREAMAQKEDM-----EERITTLEKRYLSAQRESTSI-----HDMNDKLENELANKE 372
Query: 182 ALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQ-------AEAENARLQL 234
A++ ++ RQLQ E A Q+ +A L + +L Q AE + ++
Sbjct: 373 AILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEE 432
Query: 235 QLKKLKDE 242
+++ L+ +
Sbjct: 433 RMRHLEGQ 440
>gi|8922940 gamma-taxilin [Homo sapiens]
Length = 528
Score = 37.0 bits (84), Expect = 0.035
Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 9/115 (7%)
Query: 194 LQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQ-------LKKLKDEYVLR 246
+Q AREE + A + L Q QL Q + NA+L+ + LKKL ++Y LR
Sbjct: 227 MQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALR 286
Query: 247 LQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHK 301
+H V Q L+ + E R RE L A S HK
Sbjct: 287 EEHI--DKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHK 339
>gi|122692281 hypothetical protein LOC645369 [Homo sapiens]
Length = 621
Score = 37.0 bits (84), Expect = 0.035
Identities = 78/327 (23%), Positives = 115/327 (35%), Gaps = 49/327 (14%)
Query: 93 LESRVLELE---LRGDGTSQGCAVPVE--SDPRHPRA-AAQELRHKAQVPGHSDDHRFQV 146
++SR LEL+ G G + G A + S P HP A + R A P + R
Sbjct: 254 VQSRGLELKPGGCGGSGDAFGAAAMLAKGSWPPHPAAPSGGRPRGAASPPDLASSPRCPR 313
Query: 147 QPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQ 206
+P + +R SG+ G + A A + + + G + A +
Sbjct: 314 EPPSLAEAVYSVYRERSGVAGSRRAAAATAAAAASSCSSPAPCSPPESWGRQSTASSFVD 373
Query: 207 RLATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPA 266
+ +L G+ R +AE A C+WQ G+ + P
Sbjct: 374 SSLSAFALLPLQGGRDRGGDAEGAS------------------CSWQRPPGERGSQEIPR 415
Query: 267 --TTALRTFLEATLEDIRAAHRSREQQ----LARAARSYHKRL------VDLSRRHEELL 314
T L +R A R E+ ARAAR RL L RR L
Sbjct: 416 GELDLSMTNLRGAEGSMRGARREPEEPEGAVAARAARGQGGRLPRTGRYAALRRRSTSGL 475
Query: 315 VAYRAPGNPQAIFDIASLDLEPLPVPLVTDFSHREDQHGGPGALLSSPKKRPGGASQGGT 374
YRAP +P+ S D + P+ S G P P +R G+SQ
Sbjct: 476 PDYRAPPSPEPPPSPGSADPDSSPLAKAASPSPPLRLEGSP------PTRRDSGSSQSD- 528
Query: 375 SEPQGLDAASWAQIHQKLRDFSRSTQS 401
D +S + + LR+ ST+S
Sbjct: 529 ------DPSSSNKGYTPLREAGTSTES 549
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 37.0 bits (84), Expect = 0.035
Identities = 63/289 (21%), Positives = 111/289 (38%), Gaps = 54/289 (18%)
Query: 44 EAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELR 103
E+ + LA+ +E+ + + ++ + L+ Q E+E+ LK E L
Sbjct: 965 ESALKTTLAMKEEKIVLLEAQMEE----KASLNRQLESELQMLKKECETLRQ-------- 1012
Query: 104 GDGTSQGCAVPVESDPRHP--RAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRL 161
+QG +++ +HP + AA +A PGH + ++ K+ E R
Sbjct: 1013 ----NQGEGQHLQNSFKHPAGKTAASHQGKEAWGPGHKEATMELLRVKDRAI---ELERN 1065
Query: 162 GSGLQGE---VKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSC 218
+ LQ E +K L+H E + +++ TL +Q +E +
Sbjct: 1066 NAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQSAFLQEHNT--------------TL 1111
Query: 219 QGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATL 278
Q Q + + EN+ L Q L +Y L H + E+ Q TA EA L
Sbjct: 1112 QTQTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENESLQRQQEQLTAA---YEALL 1168
Query: 279 EDIRAAHRSREQQLAR---------AARSYHKRL----VDLSRRHEELL 314
+D E+Q A ++ H+ L +L RH ++L
Sbjct: 1169 QDHEHLGTLHERQSAEYEALIRQHSCLKTLHRNLELEHKELGERHGDML 1217
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 36.6 bits (83), Expect = 0.046
Identities = 48/194 (24%), Positives = 81/194 (41%), Gaps = 19/194 (9%)
Query: 55 KEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVP 114
++QQ ++ ++ D+++ + + L+ EI L+ R+ E E R SQ
Sbjct: 708 RQQQETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQS---- 763
Query: 115 VESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALE 174
V S R + L Q S ++ KN + RLG Q + A+E
Sbjct: 764 VSSTTRPLLRQIENL----QATLGSQTSSWEKLEKNLSD------RLGES-QTLLAAAVE 812
Query: 175 HQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQL 234
+ A + L+ + ++ R R Q L S + +L + E EN R Q+
Sbjct: 813 RERAATEELLANKIQMS-SMESQNSLLRQENSRFQAQ---LESEKNRLCKLEDENNRYQV 868
Query: 235 QLKKLKDEYVLRLQ 248
+L+ LKDEYV L+
Sbjct: 869 ELENLKDEYVRTLE 882
>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
Length = 1989
Score = 36.2 bits (82), Expect = 0.060
Identities = 19/51 (37%), Positives = 29/51 (56%)
Query: 348 REDQHGGPGALLSSPKKRPGGASQGGTSEPQGLDAASWAQIHQKLRDFSRS 398
R G LL P++RP +++GG S G ++S + Q+LR+FSRS
Sbjct: 39 RSSSSSSGGGLLPYPRRRPPHSARGGGSGGGGGSSSSSSSSQQQLRNFSRS 89
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,238,596
Number of Sequences: 37866
Number of extensions: 960845
Number of successful extensions: 4114
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 3912
Number of HSP's gapped (non-prelim): 370
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.