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Search of human proteins with 19923899
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923899 coiled-coil domain containing 45 [Homo sapiens]
(821 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923899 coiled-coil domain containing 45 [Homo sapiens] 1647 0.0
gi|148746195 trichohyalin [Homo sapiens] 70 6e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 1e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 2e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 58 4e-08
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 58 4e-08
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 57 9e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 56 2e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 54 4e-07
gi|7705415 hook homolog 1 [Homo sapiens] 54 6e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 54 6e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 53 1e-06
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 53 1e-06
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 52 2e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 2e-06
gi|148746218 TAO kinase 3 [Homo sapiens] 52 2e-06
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 52 2e-06
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 51 4e-06
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 51 4e-06
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 51 4e-06
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 51 4e-06
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens] 51 4e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 50 6e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 50 6e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 50 6e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 50 6e-06
gi|27436948 lamin A/C isoform 3 [Homo sapiens] 50 8e-06
gi|5031875 lamin A/C isoform 2 [Homo sapiens] 50 8e-06
gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens] 50 8e-06
gi|34878777 ring finger protein 20 [Homo sapiens] 50 1e-05
>gi|19923899 coiled-coil domain containing 45 [Homo sapiens]
Length = 821
Score = 1647 bits (4264), Expect = 0.0
Identities = 821/821 (100%), Positives = 821/821 (100%)
Query: 1 MAGSDAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPDLIVIPRSQED 60
MAGSDAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPDLIVIPRSQED
Sbjct: 1 MAGSDAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPDLIVIPRSQED 60
Query: 61 DAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNLLEIFDGLLEYLTERISETSH 120
DAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNLLEIFDGLLEYLTERISETSH
Sbjct: 61 DAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNLLEIFDGLLEYLTERISETSH 120
Query: 121 EKSETEQYFKESDRGERLEEPESTKESKSSWKRVSFGRCSLSSEMLGPSWDGDEAESTGE 180
EKSETEQYFKESDRGERLEEPESTKESKSSWKRVSFGRCSLSSEMLGPSWDGDEAESTGE
Sbjct: 121 EKSETEQYFKESDRGERLEEPESTKESKSSWKRVSFGRCSLSSEMLGPSWDGDEAESTGE 180
Query: 181 IIRLGDTAHTFSLRSNGAQCPNEMLSKKALASPSSKSHEDMLYPPSVLSKSRTSFVEDTE 240
IIRLGDTAHTFSLRSNGAQCPNEMLSKKALASPSSKSHEDMLYPPSVLSKSRTSFVEDTE
Sbjct: 181 IIRLGDTAHTFSLRSNGAQCPNEMLSKKALASPSSKSHEDMLYPPSVLSKSRTSFVEDTE 240
Query: 241 TLSVSGIPNARKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLHSSHCSPAVNSTGEHTE 300
TLSVSGIPNARKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLHSSHCSPAVNSTGEHTE
Sbjct: 241 TLSVSGIPNARKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLHSSHCSPAVNSTGEHTE 300
Query: 301 FSGDLDDGLFLISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASSCNSPFPQRPR 360
FSGDLDDGLFLISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASSCNSPFPQRPR
Sbjct: 301 FSGDLDDGLFLISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASSCNSPFPQRPR 360
Query: 361 KRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQ 420
KRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQ
Sbjct: 361 KRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQ 420
Query: 421 HSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQ 480
HSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQ
Sbjct: 421 HSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQ 480
Query: 481 AQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKT 540
AQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKT
Sbjct: 481 AQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKT 540
Query: 541 TTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKE 600
TTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKE
Sbjct: 541 TTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKE 600
Query: 601 ACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENR 660
ACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENR
Sbjct: 601 ACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENR 660
Query: 661 QQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDE 720
QQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDE
Sbjct: 661 QQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDE 720
Query: 721 QRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEI 780
QRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEI
Sbjct: 721 QRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEI 780
Query: 781 QQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPSL 821
QQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPSL
Sbjct: 781 QQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPSL 821
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 70.5 bits (171), Expect = 6e-12
Identities = 101/481 (20%), Positives = 211/481 (43%), Gaps = 65/481 (13%)
Query: 348 ASSCNSPFPQRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGN 407
A + S RPRK+ ++ + EK +R SEL W + R +++ + + + T
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ-EEERAHRQQQEEEQRRDFTWQ 770
Query: 408 EEVEDGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKR 467
+ E+ +E + R LS R PP R + +Q E ++
Sbjct: 771 WQAEEKSE----------------RGRQRLSAR--PPLREQ--------RERQLRAEERQ 804
Query: 468 QRKPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTP 527
QR+ R E E+E RR + +E L+ E+EE+ ++ R + +++
Sbjct: 805 QREQR----------FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
Query: 528 ECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLL--PLMLEQFPFLYVSGPTLSK 585
+ R+ + + R + K H+L P + EQ L +
Sbjct: 855 GLQED---QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR----KEQQLLQ 907
Query: 586 MWKQQIAQVEQLKK---EACRENRSKKKLQDEIEEALR--RHDLLTTLVKKEYEHNKRLQ 640
++++ + E+ K+ E R+ R +++LQ E E+ LR R +++Y +K+LQ
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 641 DFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREE---MIFKKLFE 697
++ Q L + K RQ+ R +KY ++ +Q + + RE+ +++ +
Sbjct: 968 QKEE----QLLGEEPEKRRRQE--REKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 698 EGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAR 757
+ +Q++ + LR +++R ++R R E + ++ +++ L E ++ QEL+ +
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ--EEEQLLGEERETRRRQELERQ 1079
Query: 758 EKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRE---LEAERFRSRLQLASFQ 814
+ + + + ++ LR + EK +Q ++ + ++++ E L ER + R Q Q
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Query: 815 Y 815
Y
Sbjct: 1140 Y 1140
Score = 68.2 bits (165), Expect = 3e-11
Identities = 85/455 (18%), Positives = 185/455 (40%), Gaps = 36/455 (7%)
Query: 357 QRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEE 416
Q +R ++E + E+ Q+ + L+ +E+ + +E+ E+ E+ E+
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLR-------REQEERREQQLRREQEEERREQ 362
Query: 417 TLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDV 476
L + + + R +RR+ R + + +Q R+ Q+ RE +
Sbjct: 363 QLRREQE--------EERREQQLRREQQLRREQ----QLRREQQL---RREQQLRREQQL 407
Query: 477 RQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIY 536
R+ Q + RE + + QE + HE+E +++ R + R+ + + + +
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 537 SRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQ 596
++ Q L+ + + +K+ E + ++ ++Q + EQ
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE----------QQLRREQEERREQ 517
Query: 597 LKKEACRENRSKKKLQDEI----EEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLT 652
K E R +++L+ E E+ RR LL +K E +R Q K +R
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Query: 653 QSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRN 712
K +E R+Q R+ + +L + + +EE ++L E ++++
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 713 YAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKREL 772
+E+R +Q RR Q E +++ L + + +EH+E + ++ + + + +
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697
Query: 773 RSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSR 807
+S++ K QL+ V+ R + E R R
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Score = 63.9 bits (154), Expect = 6e-10
Identities = 104/485 (21%), Positives = 203/485 (41%), Gaps = 48/485 (9%)
Query: 357 QRPRKRLTEQELH-----DVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVE 411
QR R++ EQE + SEK +RL + D + R +++ +EE EE
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEK-QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ- 192
Query: 412 DGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKP 471
+ ++ + + R L +RRK R + + F E +++ +
Sbjct: 193 --LQSCKGHETEEFPDEEQLRRRELLELRRKG--REEKQQQRRERQDRVFQEEEEKEWRK 248
Query: 472 RETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHE-------KEEETEKIYRGEAVRK 524
RET +R+ + + E +R+ + +E + L E +E++ +++ R + +R+
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 525 GTPEC----------SQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFP 574
E Q + + Q LR + + + E L +
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 575 FLYVSGPTLSKMWKQQIAQVEQLKKEAC--RENRSKKKLQDEIEEALRRHDLLTT--LVK 630
L + +QQ+ + +QL++E RE + +++ Q E+ LRR L ++
Sbjct: 369 EEERREQQLRR--EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 631 KEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVR---ARKYYDDYRVQLCAKMMRMRTR 687
+E E + Q + R QRL + + +E R + R ++ + R Q + R
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQ-EERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 688 EEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAI 747
E + KL EE Q++R +E+R EQR + Q+E + ++ + + L E
Sbjct: 486 ERWL--KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 748 SQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFREL---EAERF 804
+ Q LK E+ + L + +RE R K E+E + +D + + +++ + L + ER
Sbjct: 544 ERREQLLKREEEKR---LEQERREQRLKREQE--ERRDQLLKREEERRQQRLKREQEERL 598
Query: 805 RSRLQ 809
RL+
Sbjct: 599 EQRLK 603
Score = 62.4 bits (150), Expect = 2e-09
Identities = 104/484 (21%), Positives = 194/484 (40%), Gaps = 82/484 (16%)
Query: 373 EKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQHSDGIVEYGPKK 432
E+ +R D L+ G R ++K +E E + +E L Q + +
Sbjct: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Query: 433 SRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLE-----------RKRQRKPRETDVRQFQA 481
R R + L ++ ++F E R++ R+ ++ R+ Q
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
Query: 482 QAFTEAFERELRR---------HKVQENIGPLR---IHEKEEETEKIYRGEAVRKGTPEC 529
+ F E E+E R+ K+QE P R + E+EE+ K+ R E R+ E
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEE-EPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 530 SQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQ 589
Q R Q LR + + + E + +Q
Sbjct: 295 QQ----QQRLRREQQLRRKQEEERREQQEERREQQ-------------------ERREQQ 331
Query: 590 QIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQ 649
+ + +QL++E +E R +++L+ E EE R L ++E E +R Q + R Q
Sbjct: 332 EERREQQLRRE--QEERREQQLRREQEEERREQQL-----RREQEEERREQQLR---REQ 381
Query: 650 RLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMR-MRTREEMIFKKLFEEGLNIQK---- 704
+L + + QQ+ R ++ + +++ ++ R + R E ++ EE + QK
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Query: 705 QRLRDLRNYAKEKRD-----------EQRRRHQDELDSMENYYKDQFSLLAEAISQEHQE 753
+R + L+ +E+RD EQ RR Q E ++++ L E +E +E
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE---EERRE 498
Query: 754 LKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASF 813
+ R + Q + + +RE R K ++E ++LQ + ++L E+ R QL
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE------QQLRREQEERREQLLKR 552
Query: 814 QYSK 817
+ K
Sbjct: 553 EEEK 556
Score = 59.3 bits (142), Expect = 1e-08
Identities = 104/492 (21%), Positives = 210/492 (42%), Gaps = 72/492 (14%)
Query: 320 KWEVYPAQVQGPR--TRKPPKGKRNENRATASSCNSPFPQRPRKRLTEQELHDVSEKLS- 376
+W+ +G + + +PP ++ E + A QR ++ L E+E + +
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ----QREQRFLPEEEEKEQRRRQRR 825
Query: 377 QRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRPG 436
+R EL ++ + +E+ +E +E EDG +E + + +K R
Sbjct: 826 EREKELQFLEE-------EEQLQRRERAQQLQEEEDGLQEDQERRRSQ-EQRRDQKWRWQ 877
Query: 437 LSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERELRRHK 496
L RK R H+L P Q L +++Q E + Q + ERE RR +
Sbjct: 878 LEEERKR--RRHTLYAKPA---LQEQLRKEQQLLQEEEEELQRE--------EREKRRRQ 924
Query: 497 VQENIGPLRIHEK-EEETEKIYRGEAVRKGTPECSQPWKIYSR-KTTTQSLRGGLPKPNK 554
QE R E+ ++E E++ R E ++ E + ++ + + + L G P+ +
Sbjct: 925 EQER--QYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982
Query: 555 AVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKM-WKQQIAQVEQLKKEA---CRENRSKKK 610
+ L E+ L + W++Q + ++L++E RE R K++
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042
Query: 611 LQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYY 670
LQ+ + +L + E + L + ++ RRQ L + KE Q
Sbjct: 1043 LQERERQYREEEEL-------QQEEEQLLGEERETRRRQELERQYRKEEELQ-------- 1087
Query: 671 DDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELD 730
QL + R R+E + EE L ++++L +E+R+++RR+
Sbjct: 1088 -QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL------LREEREKRRRQE----- 1135
Query: 731 SMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQN 790
+E Y+++ E + QE ++L RE+ + + +++R+ R E+E+QQ ++ + +
Sbjct: 1136 -LERQYREE-----EEVQQEEEQL-LREEPEKRRRQELERQYRE--EEELQQEEEQLLRE 1186
Query: 791 DDDVFFRELEAE 802
+ + +E E +
Sbjct: 1187 EQEKRRQERERQ 1198
Score = 56.6 bits (135), Expect = 9e-08
Identities = 88/465 (18%), Positives = 183/465 (39%), Gaps = 39/465 (8%)
Query: 357 QRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGT-- 414
+R R+ E+EL E+L E + R +E+ +EE EE E
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Query: 415 --------EETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERK 466
EE L Q + ++ +K R R+ R + + +Q E
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRR------RQELERQYREEEEVQQEEEQLLREEP 1158
Query: 467 RQRKPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGT 526
+R+ +E + + + + + E+ LR + + R + +EEE ++ R + R
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 527 PECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKM 586
W+ K K + + E S L Q ++ G +
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
Query: 587 WKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCI 646
+Q+ + +Q + E + ++ +E +EA RR +K E + L++ ++
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLER---EEQKEAKRRD-------RKSQEEKQLLREEREEK 1328
Query: 647 RRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQR 706
RR++ T K +E +Q+++ R+ R + K R + +K EE +QR
Sbjct: 1329 RRRQETDRKFRE-EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEE-----EQR 1382
Query: 707 LRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLH 766
LR K ++EQ+ R Q+ + +F + +S++ ++ K RE+ Q
Sbjct: 1383 LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ 1442
Query: 767 KVKR-------ELRSKMEKEIQQLQDMITQNDDDVFFRELEAERF 804
+ +R +LR + ++ ++ + ++ + ++ R+ +F
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
Score = 50.4 bits (119), Expect = 6e-06
Identities = 106/496 (21%), Positives = 208/496 (41%), Gaps = 61/496 (12%)
Query: 320 KWEVYPAQVQGPRTRKPP-KGKRNENRATASSCNSPFPQRPRKRLTEQELHDVSEKLSQR 378
KW+ P + R K KG+ NE + R R ++Q+L + + +R
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLED------SQLRDRQSQQDLQHLLGEQQER 1277
Query: 379 LSELDWMLKSALGDRIKEKTDH---KEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRP 435
E + R +++ H +E+ E+ E + SQ ++ ++ R
Sbjct: 1278 DREQERR-------RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKR- 1329
Query: 436 GLSMRRKPPYRSHSLSPSPVNKHKQFHLERK-RQRKPRETDVR-QFQAQAFTEAFERELR 493
RR+ R + + ++ L R+ R RK RE ++R Q Q + F E E+ LR
Sbjct: 1330 ----RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEE-EQRLR 1384
Query: 494 RHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPN 553
R + + + +E E+ R + RK E Q SR+ + R +
Sbjct: 1385 RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ----LSRQERDRKFR----EEE 1436
Query: 554 KAVPMKVSEHSLLP----LMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKK 609
+ V + E L L E+ L + +QQ+ + E+ +K E + ++
Sbjct: 1437 QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR 1496
Query: 610 KLQDEI--EEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRAR 667
+ +D E+ LR + +++E + +++ + K Q+L + + + R+Q R R
Sbjct: 1497 QERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD-RDR 1555
Query: 668 KYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQD 727
K+ ++ + +R E+ + ++ + +++Q++R K DEQ+ R Q+
Sbjct: 1556 KFREE-------EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Query: 728 ELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQ---QLQ 784
+ +F ++ Q L+ RE+ Q LH+ +R+ R +E+E Q Q +
Sbjct: 1609 GQQQLRQERDRKF-------REDEQLLQEREEQQ---LHRQERD-RKFLEEEPQLRRQER 1657
Query: 785 DMITQNDDDVFFRELE 800
+ ++D D FRE E
Sbjct: 1658 EQQLRHDRDRKFREEE 1673
Score = 50.1 bits (118), Expect = 8e-06
Identities = 74/359 (20%), Positives = 163/359 (45%), Gaps = 42/359 (11%)
Query: 464 ERKRQRKPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEE-ETEKIYRGEAV 522
E++ +R+ R RQ + + F E E +LR+ + ++ + K E +K+ R E
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFRE--EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 523 RKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSG-P 581
RK + Q R+ Q LR + + + E L ++ ++ P
Sbjct: 1595 RKFMEDEQQ----LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 582 TLSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQD 641
L + ++Q QL+ + R+ R +++L E EE R E +++ ++
Sbjct: 1651 QLRRQEREQ-----QLRHDRDRKFREEEQLLQEGEEQQLRRQ----------ERDRKFRE 1695
Query: 642 FKDCIRRQRLTQSKIKENRQQIVRA---RKYYDDYRVQLCAKMMRMRTREEMIFKKLFEE 698
+ +RRQ + K + QQ+ R RK+ ++ +++ + ++R +E ++K+ EE
Sbjct: 1696 EEQQLRRQE-RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER--YRKILEE 1752
Query: 699 GLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKARE 758
++LR R + +R E+ R+ ++E + + ++Q E+ + +E + R+
Sbjct: 1753 ------EQLRPEREEQQLRRQERDRKFREE-EQLRQEREEQQLRSQESDRKFREEEQLRQ 1805
Query: 759 KSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSK 817
+ + Q L +R+ + + E+E QL+ + + R+ ++R+ Q A+ + S+
Sbjct: 1806 EREEQQLRPQQRDGKYRWEEEQLQLE------EQEQRLRQERDRQYRAEEQFATQEKSR 1858
Score = 36.6 bits (83), Expect = 0.097
Identities = 61/290 (21%), Positives = 125/290 (43%), Gaps = 42/290 (14%)
Query: 452 PSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERELRRH----KVQENIGPLRIH 507
P + ++ L R RK RE + Q E E++LRR K +E LR
Sbjct: 1650 PQLRRQEREQQLRHDRDRKFREEE------QLLQEGEEQQLRRQERDRKFREEEQQLRRQ 1703
Query: 508 EKE----EETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEH 563
E+E +E +++ R E RK E + ++T + LR + + E
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREE-----EQLRQETEQEQLRR-----QERYRKILEEE 1753
Query: 564 SLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHD 623
L P EQ ++Q + ++E R+ R +++L+ + + R +
Sbjct: 1754 QLRPEREEQ-------------QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 624 LLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMR 683
++E + + +D K ++L Q + +E R + R R+Y + + A +
Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQL-QLEEQEQRLRQERDRQYRAEEQF---ATQEK 1856
Query: 684 MRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSME 733
R E+ ++++ ++ ++++LR+ + +++++EQR R E+ S E
Sbjct: 1857 SRREEQELWQEEEQKRRQERERKLRE-EHIRRQQKEEQRHRQVGEIKSQE 1905
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 59.3 bits (142), Expect = 1e-08
Identities = 62/290 (21%), Positives = 135/290 (46%), Gaps = 23/290 (7%)
Query: 534 KIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPL-------MLEQFPFLY--VSGPTLS 584
++Y T + L+ + + +P+ SE S + L LE+ FL V TL
Sbjct: 212 ELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 271
Query: 585 K-MWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFK 643
+ MW+Q+ E+L+++ + + ++K+ + E + + +K + KRL++ +
Sbjct: 272 EEMWRQE----EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE 327
Query: 644 DCIRRQR---LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGL 700
+R Q Q +++E +Q+ + + ++ + +M +EE ++++ E+ +
Sbjct: 328 KELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ--EKQM 385
Query: 701 NIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKS 760
Q+Q++RD E +DE+ R ++ + E + +Q + E + QE K R++
Sbjct: 386 REQEQKMRDQEERMWE-QDERLREKEERMREQEKMW-EQVEKMREEKKMQEQEKKTRDQE 443
Query: 761 QAQTLHKVKRELRSKM--EKEIQQLQDMITQNDDDVFFRELEAERFRSRL 808
+ + RE KM E+E + Q+ Q ++ + + E E + RL
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Score = 47.8 bits (112), Expect = 4e-05
Identities = 45/215 (20%), Positives = 111/215 (51%), Gaps = 29/215 (13%)
Query: 585 KMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKD 644
KMW+Q VE++++E + +KK +D+ EE ++ + + KK E + +++ ++
Sbjct: 418 KMWEQ----VEKMREEK-KMQEQEKKTRDQ-EEKMQEEERIREREKKMREEEETMREQEE 471
Query: 645 CIRRQR--LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNI 702
+++Q + + + KE +QQ + +K + + +M+ +EE I++
Sbjct: 472 KMQKQEENMWEQEEKEWQQQRLPEQK-------EKLWEQEKMQEQEEKIWE--------- 515
Query: 703 QKQRLRDLRN-YAKEK---RDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKARE 758
Q++++RD + +EK R E+ R +D++ E +DQ + + + ++ + +E
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575
Query: 759 KSQAQTLHKVKRELRSK-MEKEIQQLQDMITQNDD 792
K K++ E R + EK++++ ++M+ + ++
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Score = 36.2 bits (82), Expect = 0.13
Identities = 80/452 (17%), Positives = 180/452 (39%), Gaps = 74/452 (16%)
Query: 358 RPRKRLTEQE--LHDVSEKLSQ--RLSELDWMLKSALGD--RIKEKTDHKEENTGNEEVE 411
R K++ EQE D EK+ + R+ E + ++ +EK +EEN +E +
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 412 DGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERK--RQR 469
+ ++ L + + + E + + ++ R ++ + + E+K RQ
Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR---------DQEEMWGQEKKMWRQE 537
Query: 470 KPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEET----EKIYRGEAVRKG 525
K RE + + ++ + E + ++ QE + E+E++T EK+ E +R+
Sbjct: 538 KMREQEDQMWEQE---EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Query: 526 TPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTL-- 583
+ + ++ + + + + + E M EQ ++ +
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK-----MQEQEEKMWEQEEKMWE 649
Query: 584 --SKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQD 641
KMW+QQ ++ K + + ++K+Q++ E+ + + KK E K+ D
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE----KMEKKTQEQEKKTWD 705
Query: 642 FKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLN 701
Q K++E R +K MR EEM +
Sbjct: 706 -----------QEKMREEESMREREKK---------------MREEEEM---------MR 730
Query: 702 IQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREK-- 759
Q++++++ +E+ +E + + + E ++ Q + EH++++ +EK
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 760 SQAQTLHKVKRELRSKMEKEIQQLQDMITQND 791
Q + + + ++R + EK Q + M Q +
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Score = 31.2 bits (69), Expect = 4.1
Identities = 61/289 (21%), Positives = 108/289 (37%), Gaps = 42/289 (14%)
Query: 357 QRPRKRLTEQE--LHDVSEKL--SQRLSELDWMLKSALGDRIKEKTDHKEENTGNEE-VE 411
Q +++ EQE + + EK+ QRL E L + +EK +EE +E +E
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 412 DGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKP 471
T+E + D +K R SMR + + K E K Q +
Sbjct: 694 KKTQEQEKKTWD------QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747
Query: 472 RETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQ 531
E Q + E E+ + ++ E L HEK +E EKI+ E + E
Sbjct: 748 EEM---WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEE--- 801
Query: 532 PWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQI 591
+ + +RG K M+ E + KMW Q+
Sbjct: 802 -----KMRGQEEKMRGQEEK------MRGQEEKM--------------WGQEEKMWGQEE 836
Query: 592 AQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQ 640
Q +K +E + ++K+Q + E+ + + + +K E ++++
Sbjct: 837 KMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 58.9 bits (141), Expect = 2e-08
Identities = 84/434 (19%), Positives = 188/434 (43%), Gaps = 53/434 (12%)
Query: 357 QRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEE 416
++ K ++E+ E+ +R E+ W + + R E+ H++E +E + EE
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI--RELEEKMHEQEKIREQEEKRQEEE 417
Query: 417 TLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERK--RQRKPRET 474
+ + K+ M R+ + K + E K Q K RE
Sbjct: 418 KIREQE--------KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 475 DVRQFQAQAFTEAFERELRRHKVQENIGPLR--IHEKEE----ETEKIYRGEAVRKGTPE 528
+ RQ Q E + +E + H+ QE I + +HE+EE + EK++R E + E
Sbjct: 470 EKRQEQE----EMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEE 524
Query: 529 CSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWK 588
KI ++ + + + + H + E+ KMW+
Sbjct: 525 -----KIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE-----KRQEQEDKMWR 574
Query: 589 QQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRR 648
Q+ E+++++ + R ++K++++ E+ + + + +K E +++Q+ ++ IR
Sbjct: 575 QE----EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
Query: 649 QRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLR 708
Q + KI+E + + + ++C + +M+ +EE ++++ EE + Q++++R
Sbjct: 631 Q---EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ--EEKIREQEKKIR 685
Query: 709 DLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKV 768
+ E++ R Q+E+ M+ + + + QE + + EK + Q
Sbjct: 686 E---------QEEKIREQEEM--MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
Query: 769 KRELRSKMEKEIQQ 782
++E+R + ++E Q
Sbjct: 735 EQEVRLRQQEEKMQ 748
Score = 48.9 bits (115), Expect = 2e-05
Identities = 54/272 (19%), Positives = 117/272 (43%), Gaps = 24/272 (8%)
Query: 534 KIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQ 593
++Y T + L+ K + + + SE S + L +++ L + Q A+
Sbjct: 208 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ-AE 266
Query: 594 VEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQ 653
+ L KE KLQ ++EE + L +K + +++Q++++ I+ Q +
Sbjct: 267 ADHLGKEL---QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ---E 320
Query: 654 SKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNY 713
KI+E ++I + + K +MR +EEM+++K ++++R
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK---------EEKMRRQEEM 371
Query: 714 AKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELR 773
EK ++ RR+ + + E + E + H++ K RE+ + + + RE
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEK--------IRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 774 SKMEKEIQQLQDMITQNDDDVFFRELEAERFR 805
+ E+E + + + + RE E + +R
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Score = 47.0 bits (110), Expect = 7e-05
Identities = 40/210 (19%), Positives = 110/210 (52%), Gaps = 19/210 (9%)
Query: 586 MWKQQ--IAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFK 643
MW+++ + + E++ E + R ++++ E EE +RR + + +E +++++ +
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM------WEKEEKIRELE 397
Query: 644 DCIRRQ-RLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNI 702
+ + Q ++ + + K ++ +R ++ + ++ + ++R +EE I ++ E+ +
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ--EKKMWR 455
Query: 703 QKQRLRDLRNYAKEK-RDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQ 761
Q++++ + +EK R+E++R+ Q+E+ E +Q + + QE K R+ Q
Sbjct: 456 QEEKIHE-----QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK--Q 508
Query: 762 AQTLHKVKRELRSKMEKEIQQLQDMITQND 791
+ + + + ++R + EK +Q + M Q +
Sbjct: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEE 538
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 57.8 bits (138), Expect = 4e-08
Identities = 85/455 (18%), Positives = 194/455 (42%), Gaps = 79/455 (17%)
Query: 366 QELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGN-EEVEDGTEETLSQHSDG 424
+EL VS KL ++ E + L + L + +EK +EE EE EE + + +
Sbjct: 272 KELQSVSAKLQAQVEENE--LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 329
Query: 425 IVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLER---KRQRKPRETDVRQFQA 481
I E K R M K + K LE +++ K RE + + +
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ 389
Query: 482 QAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTT 541
+ E E+ K++E +++E+ K++R E + E
Sbjct: 390 EKIREQEEKRQEEEKIREQ------EKRQEQEAKMWRQEEKIREQEE------------- 430
Query: 542 TQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQ--IAQVEQLKK 599
K+ E KMW+Q+ I + E++++
Sbjct: 431 -----------------KIREQE-------------------KKMWRQEEKIHEQEKIRE 454
Query: 600 EACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNK-RLQDFKDCIRRQRL--TQSKI 656
E R+ + + Q EE +R + + +K +E K R Q+ K + +++ + KI
Sbjct: 455 EEKRQEQEEMWRQ---EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI 511
Query: 657 KENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKE 716
+E +++ R + + ++ + ++R +EEM+ ++ EE + Q++++++ K
Sbjct: 512 REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ--EEKMGEQEEKMQE---QEKM 566
Query: 717 KRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKV--KRELRS 774
+R E++ R Q+E + K++ E I ++ ++++ +E+ + K+ + E
Sbjct: 567 RRQEEKIREQEEKIREQ---KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623
Query: 775 KMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQ 809
+ E+++Q+ ++ + + ++ ++ +E+ + ++Q
Sbjct: 624 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Score = 50.1 bits (118), Expect = 8e-06
Identities = 59/280 (21%), Positives = 126/280 (45%), Gaps = 32/280 (11%)
Query: 534 KIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQ 593
++Y T + L+ K + + + SE S + L +++ L + Q A+
Sbjct: 208 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ-AE 266
Query: 594 VEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQ 653
+ L KE KLQ ++EE + L +K + +++Q++++ I+ Q +
Sbjct: 267 ADHLGKEL---QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ---E 320
Query: 654 SKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKK-----LFEEGLNIQKQRLR 708
KI+E ++I + + K +MR +EEM+++K EE + +++++R
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIR 380
Query: 709 DLRNYAKEKRDEQRR-RHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKS------- 760
+L +EK EQ + R Q+E E ++Q + QE K RE+
Sbjct: 381 EL----EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 761 -----QAQTLH---KVKRELRSKMEKEIQQLQDMITQNDD 792
Q + +H K++ E + + ++E+ + ++ I + ++
Sbjct: 437 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 57.8 bits (138), Expect = 4e-08
Identities = 115/541 (21%), Positives = 213/541 (39%), Gaps = 88/541 (16%)
Query: 311 LISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASSCNSPFPQRPRKRLTEQELHD 370
L SK KG + + P R + PP+ E PQ P + +E +
Sbjct: 459 LQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEP---------PQGPEGQPEWKEAEE 509
Query: 371 VSEKLSQRLS-ELDWMLKSALG-----DRIKEKTDHKEE-NTGNEEVEDGTEETLSQHSD 423
+ E + LS +L + A ++ KE+ EE G EE ED EE ++
Sbjct: 510 LGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAED-PEEKVAVSPT 568
Query: 424 GIVEYGPKKSRPGLSMRR--KPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQA 481
V + + P + + ++ + + V + Q HL +Q K ++Q +
Sbjct: 569 PPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEK-----MQQLRE 623
Query: 482 QAFTEAFERELRRHKVQE-NIGPLR------IHE-----KEEETEKIYRGEAVRKGTPEC 529
+ E E LR H+ +E ++ LR I E +EEE++++ A + + +
Sbjct: 624 KLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQA 683
Query: 530 SQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQ 589
+ ++ + Q LR L KA + + + MLEQ K+
Sbjct: 684 DEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQ--MLEQL--------------KE 727
Query: 590 QIAQVEQLKKEACRENRSKKKLQDEIEEALR--RHDLLTTLVKKEYEHNKRLQDFKDCIR 647
+I E K E N +K+K ++ E L R + + TL K+ +RL +
Sbjct: 728 EIEASE--KSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKH 785
Query: 648 RQRLT--QSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQ 705
R+ ++ Q KI+E +Q+ ++ ++Q C + R ++ +E
Sbjct: 786 REVVSSLQKKIQEAQQK--------EEAQLQKCLGQVEHRVHQKSYHVAGYEH------- 830
Query: 706 RLRDLRNYAKEKRDEQRRRHQDELDSM------------ENYYKDQFSLLAEAISQEHQE 753
+L + +EKR E H+ LD M E Y ++ AE + E
Sbjct: 831 ---ELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGE 887
Query: 754 LKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASF 813
L+ +++ + L V++E ++E ++ ++ + D E A+ ++RL L
Sbjct: 888 LERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEV 947
Query: 814 Q 814
Q
Sbjct: 948 Q 948
Score = 44.7 bits (104), Expect = 4e-04
Identities = 132/625 (21%), Positives = 230/625 (36%), Gaps = 75/625 (12%)
Query: 206 SKKALASPSSKSHEDMLYPP-----SVLSKSRTSFVEDTETLSVSGIPN---ARKLGEPI 257
S+ L S SK E+ L PP S R+ E+ G P A +LGE
Sbjct: 455 SQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDS 514
Query: 258 RAAIPLHPPYHPSE---PRAPCPIGKEYLHSSHCSPAVNSTGEHTEFSGDLDDGLFLISK 314
A++ L + P A C GKE HS G E + D ++ + +S
Sbjct: 515 AASLSLQLSLQREQAPSPPAACEKGKEQ-HSQ-----AEELGPGQEEAEDPEEKV-AVSP 567
Query: 315 LPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASSCNSPFPQRPRKRLTEQELHDVSEK 374
P S EV + P + + A A QR ++++ + EK
Sbjct: 568 TPPVSP-EVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQD--QRHLLESKQEKMQQLREK 624
Query: 375 LSQ-------RLSELDWMLKSALGDRIKEKTDHKEENTGNEEVED-----GTEETLSQHS 422
L Q RL + S+L +R+++ + +E EE + ++ +Q
Sbjct: 625 LCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 684
Query: 423 DGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQAQ 482
+ + + S L + ++ S N+ LE+ ++ Q
Sbjct: 685 EDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM---LEQLKEEIEASEKSEQAALN 741
Query: 483 AFTEAFERELRRHKVQENIGPLRIHEKEE--ETEKIYRGEAVRKGTPECSQPWKIYSRKT 540
A E ++LR E + EKE E E++ + S KI +
Sbjct: 742 AAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQ 801
Query: 541 TTQS-LRGGLPKPNKAVPMKVS-----EHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQV 594
++ L+ L + V K EH L L+ E+ + K++ QV
Sbjct: 802 KEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQV 861
Query: 595 EQLKKEACRENRSKKK------LQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRR 648
+E K++ L E+E R H+ V++E +KRL+D + RR
Sbjct: 862 MAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQE--QHKRLEDLR---RR 916
Query: 649 QRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLR 708
R + K++ D + L + ++ R ++ ++ EE +KQ+L
Sbjct: 917 HREQERKLQ--------------DLELDLETRAKDVKARLALL--EVQEETARREKQQLL 960
Query: 709 DLRNYAKEKRDEQRRRHQD-ELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHK 767
D++ K +E HQ E E+ + Q + I E Q K + +SQ L
Sbjct: 961 DVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQA 1020
Query: 768 VKRELR---SKMEKEIQQLQDMITQ 789
++L+ S +E E Q+ Q ++ +
Sbjct: 1021 QSQQLQKHFSSLEAEAQKKQHLLRE 1045
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 56.6 bits (135), Expect = 9e-08
Identities = 105/512 (20%), Positives = 209/512 (40%), Gaps = 89/512 (17%)
Query: 362 RLTEQ--ELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLS 419
RL EQ E +E + +L +L ++ ++ ++ TD +E + +E+ +
Sbjct: 1214 RLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPS-TDQQESCSSTPGLEEPLFKATE 1272
Query: 420 QHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVN---------------KHKQFHLE 464
QH ++P L P + SHS S + + ++ LE
Sbjct: 1273 QHH----------TQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELE 1322
Query: 465 RK-----RQRKPRETDVRQFQAQAFTEAFERE-LRRHKVQENIGPLRIHEKEEETEKIYR 518
K + + +V Q Q Q + E E L+ + + + +K E ++
Sbjct: 1323 LKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIA 1382
Query: 519 G-EAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLY 577
G E +R+ P+ + K+ S+K S G +A K+ ++EQ +
Sbjct: 1383 GLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE-----IIEQEDLIK 1437
Query: 578 VSGPTLSKMWKQQIAQVEQLKKEACR----------ENRSKKKLQDEIEEALRRHDLLTT 627
L K+ +++QL+ E C E+R+K+++Q +++ AL
Sbjct: 1438 ALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISR----- 1492
Query: 628 LVKKEYEHNKRLQDFKDCIRR--QRLTQSKIKENRQQIVRARKYYD----------DYRV 675
K+ + NK LQ+ R +RLT+S + + Q+ K D + R
Sbjct: 1493 --KEALKENKSLQEELSLARGTIERLTKS-LADVESQVSAQNKEKDTVLGRLALLQEERD 1549
Query: 676 QLCAKMMRMRTREEMIFK-----KLFEEGLNIQKQRL-RDLRNYA----------KEKRD 719
+L +M R + + KL EGL K++L +++ + +EK
Sbjct: 1550 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHK 1609
Query: 720 EQRRRHQDELDSMENYYKD--QFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKME 777
E ++ ++ L S EN + + + EA+ QE QEL + +S + +++L+ + E
Sbjct: 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ-EAE 1668
Query: 778 KEIQQLQDMITQNDDDVFFRELEAERFRSRLQ 809
+E++++++ + + + LE E RL+
Sbjct: 1669 QEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1700
Score = 54.3 bits (129), Expect = 4e-07
Identities = 87/444 (19%), Positives = 189/444 (42%), Gaps = 49/444 (11%)
Query: 361 KRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQ 420
K E+E D+ E+L +L+EL+ ++G+ ++ TD + +N E ++ +S+
Sbjct: 1912 KETAEEEKDDLEERLMNQLAELN----GSIGNYCQDVTDAQIKNELLESEMKNLKKCVSE 1967
Query: 421 HSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQ 480
+ + +K++ +R++ + P NK L+ + K +E Q
Sbjct: 1968 LEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKD 2027
Query: 481 AQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKT 540
+ E R K E + + E E + + RK +K+ T
Sbjct: 2028 CIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDT 2087
Query: 541 TTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKE 600
+++ R +L L+ L + ++ KQ+ +E+ ++
Sbjct: 2088 QSEAAR------------------VLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ 2129
Query: 601 ACRENRSKKKLQDEIEEALRRH---------DLLTTLVKKEYEHNKRLQDFKDCIRRQ-- 649
A ++ +KK E +ALRR ++ TL KK+ E ++LQ+ D Q
Sbjct: 2130 AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKE-VQQLQENLDSTVTQLA 2188
Query: 650 --RLTQSKIKENRQQIV-RARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQR 706
+ S ++++R +++ A+K+ + + +++EE I +L E+ ++ K +
Sbjct: 2189 AFTKSMSSLQDDRDRVIDEAKKWERKFSDAI-------QSKEEEI--RLKEDNCSVLKDQ 2239
Query: 707 LRDLRNYAKE-KRDEQRRRHQDELDSMENYYKDQF-SLLAEAISQEHQELKAREKSQAQT 764
LR + + +E K + R H ++ + + Q + + + E++EL ++ +
Sbjct: 2240 LRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2299
Query: 765 LHKVKRELRSKMEKEIQQLQDMIT 788
H + EL +K+E E++ L+D +T
Sbjct: 2300 YHSSQNEL-AKLESELKSLKDQLT 2322
Score = 39.7 bits (91), Expect = 0.011
Identities = 92/472 (19%), Positives = 186/472 (39%), Gaps = 71/472 (15%)
Query: 381 ELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRPGLSMR 440
+ D +++ L + +++D + NT E+V+ E L+ +VE + + ++
Sbjct: 21 DTDQNMRAPLDPELHQESDMEFNNTTQEDVQ----ERLAYAEQLVVELKDIIRQKDVQLQ 76
Query: 441 RKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFT-----EAFERELRRH 495
+K + NK K+ L K + + + +AQ T E +L +H
Sbjct: 77 QKDEALQEERKAAD-NKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKH 135
Query: 496 KVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKA 555
E+E E EKI K+ ++ +L+ L +
Sbjct: 136 DKSST-------EEEMEIEKIKH---------------KLQEKEELISTLQAQLTQAQAE 173
Query: 556 VPMKVSEHSLLPLMLEQF-----PFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKKK 610
P + S +M++Q F+ LS+ +Q AQ +K+A E + +
Sbjct: 174 QPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLH 233
Query: 611 LQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYY 670
+DE+ + + + D+ T + +K ++L++ ++ + + ++++ + QQ + A +
Sbjct: 234 -EDELLQLVTQADVETEMQQKLRVLQRKLEEHEESL----VGRAQVVDLLQQELTAAEQR 288
Query: 671 DDYRVQLCAKM------MRMRTREEMIFKKLFEEGLNIQ-KQRLRDLRNYAKE-----KR 718
+ Q +M +R E K+ E + ++ +R N +E ++
Sbjct: 289 NQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQ 348
Query: 719 DEQRRRHQDELDS----MENYYKDQFS------LLAEAISQEHQELKAREKSQAQTLHKV 768
EQ + Q EL+S +E +K + L + QE Q K Q L +
Sbjct: 349 FEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQD 408
Query: 769 KRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPS 820
K E + + IQQL+D + Q + E +F +RL L + + S
Sbjct: 409 KNEQAVQSAQTIQQLEDQLQQ-------KSKEISQFLNRLPLQQHETASQTS 453
Score = 35.4 bits (80), Expect = 0.22
Identities = 73/351 (20%), Positives = 143/351 (40%), Gaps = 35/351 (9%)
Query: 459 KQFHLERKRQRKPRETDVRQFQA------QAFTEAFERELRRHKVQENIGPLRIHEKE-- 510
K H + + Q K + ++Q Q Q E E + ++Q + I KE
Sbjct: 1437 KALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL 1496
Query: 511 EETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLML 570
+E + + ++ +GT E T+SL + + K + L L+
Sbjct: 1497 KENKSLQEELSLARGTIE-----------RLTKSLADVESQVSAQNKEKDTVLGRLALLQ 1545
Query: 571 EQFPFLYVSGPTLSKMWKQQIAQ-VEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLV 629
E+ L ++ S + Q ++ E LK K+KL EIE +T
Sbjct: 1546 EERDKL-ITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEST-- 1602
Query: 630 KKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREE 689
+ E +K LQ + + + S E Q +V A + + +L K+ ++
Sbjct: 1603 -EWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVR---QEKQELYGKLRSTEANKK 1658
Query: 690 MIFKKLFEEGLNIQKQRLRDLRNYAKEKR------DEQRRRHQDELDSMENYYKDQFSLL 743
K+L E +++ + + +R +AK K+ +E+ R + E+ + K+ L
Sbjct: 1659 ETEKQLQEAEQEMEEMKEK-MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETL 1717
Query: 744 AEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDV 794
+ + +EL+ R K + +TL K + L S+ + +++QD+ Q + +V
Sbjct: 1718 LSSNASMKEELE-RVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNV 1767
Score = 33.5 bits (75), Expect = 0.82
Identities = 40/195 (20%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 608 KKKLQDEIEEALRRHDL----LTTLVKKEYEHNKRLQDF-KDCIRRQRLTQSKIKENRQQ 662
++ +Q I E ++HD L L+ +E E N L++ K + + +K +++
Sbjct: 2392 EEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKE 2451
Query: 663 IVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEK---RD 719
++ + D + V+ + + R R +++L E L+I ++ + ++ A E ++
Sbjct: 2452 NIQQKAQLDSF-VKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2510
Query: 720 EQR--RRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKME 777
E R R H D+L+S + E ++Q +++K + + +EL +K
Sbjct: 2511 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYA 2570
Query: 778 KEIQQLQDMITQNDD 792
K ++L++ N+D
Sbjct: 2571 KLEEKLKESEEANED 2585
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 55.8 bits (133), Expect = 2e-07
Identities = 79/454 (17%), Positives = 192/454 (42%), Gaps = 82/454 (18%)
Query: 366 QELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGN-EEVEDGTEETLSQHSDG 424
+EL VS KL ++ E + L + L + +EK +EE EE EE + + +
Sbjct: 333 KELQSVSAKLQAQVEENE--LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 390
Query: 425 IVEYGPKKSRPGLSM---RRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQA 481
I E K R M K + + +Q + +++ K RE + + +
Sbjct: 391 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 482 QAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTT 541
+ E E+ K++E +++E+ K++R E + E
Sbjct: 451 EKIREQEEKRQEEEKIREQ------EKRQEQEAKMWRQEEKIREQEE------------- 491
Query: 542 TQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQ--IAQVEQLKK 599
K+ E KMW+Q+ I + E++++
Sbjct: 492 -----------------KIREQE-------------------EKMWRQEEKIHEQEKIRE 515
Query: 600 EACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLT----QSK 655
E R+ + + Q EE +R + + +K +E ++++ ++ + RQ + K
Sbjct: 516 EEKRQEQEEMWRQ---EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572
Query: 656 IKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAK 715
I+E +++ R + + ++ + ++R +EEM ++ EE + Q++++ + +
Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQ--EEKMGEQEEKMCEQEEKMQ 630
Query: 716 EKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSK 775
E ++E+ RR ++++ E ++Q E I ++ + ++ +E+ + + E +
Sbjct: 631 E-QEEKMRRQEEKIREQEKKIREQ----EEKIREQEEMMQEQEEKMWE-----QEEKMCE 680
Query: 776 MEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQ 809
E+++Q+ ++ + + ++ ++ +E+ + ++Q
Sbjct: 681 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Score = 53.1 bits (126), Expect = 1e-06
Identities = 51/253 (20%), Positives = 130/253 (51%), Gaps = 33/253 (13%)
Query: 587 WKQQIAQVEQL---KKEACRENRSKKKLQDEI----EEALRRHDLLTTLVKKE------- 632
W+++I + E+ ++E RE K + Q+E+ EE +RR + + +++
Sbjct: 373 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 432
Query: 633 -YEHNKRLQDFKDCIRRQ-RLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEM 690
+E +++++ ++ + Q ++ + + K ++ +R ++ + ++ + ++R +EE
Sbjct: 433 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 691 IFKKLFEEGLNIQKQRLRDLRNYAKEK-RDEQRRRHQDELDSMENYYKDQFSLLAEAISQ 749
I ++ EE + Q++++ + +EK R+E++R+ Q+E+ E ++Q + +
Sbjct: 493 IREQ--EEKMWRQEEKIHE-----QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Query: 750 EHQELKAREKS-----QAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERF 804
QE K R++ Q + +H + ++R + EK +Q ++ I + ++ + RE E E+
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ-EEKIREQEEKI--REQE-EKI 601
Query: 805 RSRLQLASFQYSK 817
R + ++ Q K
Sbjct: 602 REQEEMTQEQEEK 614
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/379 (16%), Positives = 161/379 (42%), Gaps = 40/379 (10%)
Query: 357 QRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEE 416
Q + R E+++ + EK+ +R E+ W + + + + + +E+ EE+ EE
Sbjct: 380 QEEKIREQEEKIREQEEKM-RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 417 TLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDV 476
+ + + + E + + + +Q R+++ K RE +
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 498
Query: 477 RQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIY 536
+ ++ + E+ K QE R EK E E+I+R Q KI+
Sbjct: 499 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR------------QKEKIH 546
Query: 537 SRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQ 596
++ + + K + H + EQ K+W+Q+ E+
Sbjct: 547 EQEEKIRK------QEEKMWRQEEKMHDQEEKIREQE----------EKVWRQE----EK 586
Query: 597 LKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQ----RLT 652
++++ + ++K++++ E + + + +K E +++Q+ ++ +RRQ R
Sbjct: 587 IREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Query: 653 QSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRN 712
+ KI+E ++I + + ++ + +M +EE + ++ EE + Q++++ + +
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMWE-QE 703
Query: 713 YAKEKRDEQRRRHQDELDS 731
+++E+ + HQ+ L++
Sbjct: 704 VRLRQQEEKMQEHQEHLEA 722
Score = 43.1 bits (100), Expect = 0.001
Identities = 53/272 (19%), Positives = 115/272 (42%), Gaps = 38/272 (13%)
Query: 534 KIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQ 593
++Y T + L+ K + + + SE S + L +++ L + Q A+
Sbjct: 269 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ-AE 327
Query: 594 VEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQ 653
+ L KE KLQ ++EE + L +K + +++Q++++ I+ Q +
Sbjct: 328 ADHLGKEL---QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ---E 381
Query: 654 SKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNY 713
KI+E ++I + +MR +EEM+++K ++++R
Sbjct: 382 EKIREQEEKIREQEE--------------KMRRQEEMMWEK---------EEKMRRQEEM 418
Query: 714 AKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELR 773
EK ++ RR+ + + E + E + H++ K RE+ + + + RE
Sbjct: 419 MWEKEEKMRRQEEMMWEKEEK--------IRELEEKMHEQEKIREQEEKRQEEEKIREQE 470
Query: 774 SKMEKEIQQLQDMITQNDDDVFFRELEAERFR 805
+ E+E + + + + RE E + +R
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWR 502
Score = 37.0 bits (84), Expect = 0.074
Identities = 43/242 (17%), Positives = 108/242 (44%), Gaps = 39/242 (16%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIR 647
+Q ++ V KK+A R K +D + L R+ + +K E N +LQ+ +
Sbjct: 239 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELK---EKNAKLQEKLQLVE 295
Query: 648 RQRLT-QSKIKENRQQIVRARKYYDDYRVQLCAK-----------MMRMRTREEMIFKKL 695
++ Q +KE ++++ RA+ ++Q A ++ + E ++ +L
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355
Query: 696 -----------------FEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKD 738
+EE + Q++++R+ +E+ ++ RR+ + + E +
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 415
Query: 739 QFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRE 798
+ E + ++ ++++ +E+ + K+ REL KM ++ +++++ + ++ RE
Sbjct: 416 E-----EMMWEKEEKMRRQEEMMWEKEEKI-RELEEKMHEQ-EKIREQEEKRQEEEKIRE 468
Query: 799 LE 800
E
Sbjct: 469 QE 470
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 54.3 bits (129), Expect = 4e-07
Identities = 87/397 (21%), Positives = 162/397 (40%), Gaps = 90/397 (22%)
Query: 413 GTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPR 472
G +E + +DG E P S RRK RS+ + S +++ + HLE + + PR
Sbjct: 428 GQQEAKTDQADGPRE-------PPQSARRK---RSYKQAVSELDEEQ--HLEDEELQPPR 475
Query: 473 ETD--------------------VRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEE 512
V++ Q + R + + ++ N PLR+ KE+E
Sbjct: 476 SKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNT-PLRMDPKEKE 534
Query: 513 TEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKA---VPMKVSEHSLLPLM 569
+++ E +R RK + LR + +K +K+ L +
Sbjct: 535 RQRL---ENLR--------------RKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKV 577
Query: 570 LEQFPFLYVSGPTLSKMWKQQIAQV----EQLKKEACRENRSKKKLQDEIEEALRRHDLL 625
L+ + K +Q+ AQ+ E+ K+E E ++KKK
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK--------------- 622
Query: 626 TTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMR 685
KK E R + ++ R + L Q + + Q++++ +K + R++ A+ R+
Sbjct: 623 -AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 681
Query: 686 TREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAE 745
+ E ++Q R+ +E+R+++RR + +L E ++Q L AE
Sbjct: 682 EQREQ----------ERREQERREQERREQERREQERREQERQLAEQERR-REQERLQAE 730
Query: 746 AISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQ 782
+EL+ REK+ +++REL K +KE QQ
Sbjct: 731 ------RELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
Score = 53.1 bits (126), Expect = 1e-06
Identities = 79/338 (23%), Positives = 144/338 (42%), Gaps = 49/338 (14%)
Query: 439 MRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERELRRHKVQ 498
M P S+ S + ++ ++ K + + R ++R+ + +LRR KV+
Sbjct: 504 MLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEA-------EQLRRQKVE 556
Query: 499 ENIGPLRIHEKEEETEKIYRGEAVRK--GTPECSQPWKIYSRKTTTQSLRGGLPKPNKAV 556
E+ + E K+ R E +RK E + K +K Q K KA
Sbjct: 557 ED------KRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
Query: 557 PMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIE 616
+++E K +++ +VE +K+ E R + LQ E E
Sbjct: 611 EERLAEEK-----------------AKKKAAAKKMEEVEARRKQE-EEARRLRWLQQEEE 652
Query: 617 EALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQ 676
E RRH L L KK+ E +RL+ + +RL + + +E R+Q R ++ + R
Sbjct: 653 E--RRHQEL--LQKKKEEEQERLRKAAEA---KRLAEQREQERREQERREQERREQER-- 703
Query: 677 LCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYY 736
R + R E ++L E+ +++RL+ R + ++ + ++ Q + + E
Sbjct: 704 ------REQERREQE-RQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKK 756
Query: 737 KDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRS 774
K++ LAE QE QE KA+E + A V +++S
Sbjct: 757 KEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 794
Score = 41.2 bits (95), Expect = 0.004
Identities = 50/235 (21%), Positives = 108/235 (45%), Gaps = 37/235 (15%)
Query: 593 QVEQLKKEACRENRSKK----KLQDE-----IEEALRRHDLLTTLVKKEYEHN-KRLQDF 642
+ EQL+++ E++ ++ KL+ E + +A R + + KK+ E ++ +
Sbjct: 546 EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 605
Query: 643 KDCIRRQRLTQSKIKEN----RQQIVRARKYYDDY--RVQLCAKMMRMRTREEMIFKKLF 696
+ + +RL + K K+ + + V AR+ ++ R++ + R +E++ KK
Sbjct: 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665
Query: 697 EEGLNIQKQ-RLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELK 755
EE ++K + L +++R EQ RR Q+ + QE +E +
Sbjct: 666 EEQERLRKAAEAKRLAEQREQERREQERREQERRE------------------QERREQE 707
Query: 756 AREKSQAQTLHKVKREL-RSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQ 809
RE+ + + +RE R + E+E+Q+ + + + + RELE ++ + Q
Sbjct: 708 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQL-QRELEEKKKKEEQQ 761
Score = 35.8 bits (81), Expect = 0.17
Identities = 43/204 (21%), Positives = 89/204 (43%), Gaps = 18/204 (8%)
Query: 608 KKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRAR 667
K+K + +E LRR + L +++ E +KR RR + K +E +++++AR
Sbjct: 531 KEKERQRLEN-LRRKEEAEQLRRQKVEEDKR--------RRLEEVKLKREERLRKVLQAR 581
Query: 668 KYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQD 727
+ + + + ++ + + + +K EE L +K + + A +K +E R +
Sbjct: 582 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK----KKAAAKKMEEVEARRKQ 637
Query: 728 ELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMI 787
E ++ + Q E + HQEL ++K + Q + E + E+ Q+ ++
Sbjct: 638 EEEARRLRWLQQ-----EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 692
Query: 788 TQNDDDVFFRELEAERFRSRLQLA 811
+ + E ER QLA
Sbjct: 693 RREQERREQERREQERREQERQLA 716
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 53.9 bits (128), Expect = 6e-07
Identities = 47/209 (22%), Positives = 101/209 (48%), Gaps = 14/209 (6%)
Query: 593 QVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLT 652
QV+ L + E++ L E++ +H+ L ++ E L++ + +R ++
Sbjct: 377 QVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQ 436
Query: 653 QSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRN 712
Q + Q A K Y++ L A++M + RE I + + L +Q++ + R
Sbjct: 437 QDHLN---QTDASATKSYEN----LAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERI 489
Query: 713 YAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAR-EKSQAQTLHKVKRE 771
+++ EQ+ R +EL++ + K++ L + I + L+ + KS+ ++ K+K++
Sbjct: 490 EELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQK 549
Query: 772 LRSKMEK------EIQQLQDMITQNDDDV 794
L + MEK E+Q+ Q++I D+
Sbjct: 550 LEAHMEKLTEVHEELQKKQELIEDLQPDI 578
Score = 45.4 bits (106), Expect = 2e-04
Identities = 87/398 (21%), Positives = 160/398 (40%), Gaps = 77/398 (19%)
Query: 473 ETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEK---EEETEKIYRGEAVRKGTPEC 529
E V+ A E +E+ + +G L K EE E + E +R+ E
Sbjct: 145 EESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEEL 204
Query: 530 SQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTL-SKMWK 588
+ TT Q + L VSE+ ++ L+Q + T+ +K +
Sbjct: 205 DM------QVTTLQDEKNSL----------VSENEMMNEKLDQLDGSFDDPNTVVAKKYF 248
Query: 589 QQIAQVEQLKKEACRENRSK-------KKLQDEIEEALRRHDLLTTL------VKKEYE- 634
Q+EQL++E R +K ++L+ ++ E R+D LT+L +K E +
Sbjct: 249 HAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDV 308
Query: 635 -----------------HNKRLQDFKDCIRRQRLTQ-----------------SKIKENR 660
+ ++LQD D ++ + Q K R
Sbjct: 309 LRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAAR 368
Query: 661 QQIVRARKYYDDYRVQLCAKMMRMRTRE-EMIFKKLFEEGLNIQKQRLRDLRNYAKEKRD 719
Q+ ++ D V+L ++ R T EM + E L +K+RL + R+ KE +
Sbjct: 369 TQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNE 428
Query: 720 EQR--RRHQDELDSME-NYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKM 776
E R + QD L+ + + K +L AE + E++E+ R + + + L + +
Sbjct: 429 ELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKML---RLQQEGSE 485
Query: 777 EKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQ 814
+ I++LQ+ + Q + ELE E+ S+ ++ Q
Sbjct: 486 NERIEELQEQLEQKHRKM--NELETEQRLSKERIRELQ 521
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 53.9 bits (128), Expect = 6e-07
Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 23/196 (11%)
Query: 593 QVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNK------RLQDFKDCI 646
+VEQ+K+E ++ K DE E + L KK+ K R + ++
Sbjct: 587 RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 646
Query: 647 RRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQR 706
R + L Q + + Q++++ +K + R++ A+ R+ + E ++Q
Sbjct: 647 RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ----------ERREQE 696
Query: 707 LRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLH 766
R+ +E+R+++RR + +L E ++Q L AE +EL+ REK+
Sbjct: 697 RREQERREQERREQERREQERQLAEQERR-REQERLQAE------RELQEREKALRLQKE 749
Query: 767 KVKRELRSKMEKEIQQ 782
+++REL K +KE QQ
Sbjct: 750 QLQRELEEKKKKEEQQ 765
Score = 51.2 bits (121), Expect = 4e-06
Identities = 77/311 (24%), Positives = 132/311 (42%), Gaps = 42/311 (13%)
Query: 472 RETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEE------ETEKIYRGEAVRK- 524
R T +R +F E + L + +E LR + EE E K+ R E +RK
Sbjct: 522 RNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKV 581
Query: 525 -GTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTL 583
E + K +K Q K KA +++E
Sbjct: 582 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEK-----------------AK 624
Query: 584 SKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFK 643
K +++ +VE +K+ E R + LQ E EE RRH L L KK+ E +RL+
Sbjct: 625 KKAAAKKMEEVEARRKQE-EEARRLRWLQQEEEE--RRHQEL--LQKKKEEEQERLRKAA 679
Query: 644 DCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQ 703
+ +RL + + +E R+Q R ++ + R R + R E ++L E+ +
Sbjct: 680 EA---KRLAEQREQERREQERREQERREQER--------REQERREQE-RQLAEQERRRE 727
Query: 704 KQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQ 763
++RL+ R + ++ + ++ Q + + E K++ LAE QE QE KA+E + A
Sbjct: 728 QERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGAS 787
Query: 764 TLHKVKRELRS 774
V +++S
Sbjct: 788 KALNVTVDVQS 798
Score = 41.2 bits (95), Expect = 0.004
Identities = 50/235 (21%), Positives = 108/235 (45%), Gaps = 37/235 (15%)
Query: 593 QVEQLKKEACRENRSKK----KLQDE-----IEEALRRHDLLTTLVKKEYEHN-KRLQDF 642
+ EQL+++ E++ ++ KL+ E + +A R + + KK+ E ++ +
Sbjct: 550 EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 609
Query: 643 KDCIRRQRLTQSKIKEN----RQQIVRARKYYDDY--RVQLCAKMMRMRTREEMIFKKLF 696
+ + +RL + K K+ + + V AR+ ++ R++ + R +E++ KK
Sbjct: 610 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 669
Query: 697 EEGLNIQKQ-RLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELK 755
EE ++K + L +++R EQ RR Q+ + QE +E +
Sbjct: 670 EEQERLRKAAEAKRLAEQREQERREQERREQERRE------------------QERREQE 711
Query: 756 AREKSQAQTLHKVKREL-RSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQ 809
RE+ + + +RE R + E+E+Q+ + + + + RELE ++ + Q
Sbjct: 712 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQL-QRELEEKKKKEEQQ 765
Score = 35.4 bits (80), Expect = 0.22
Identities = 40/184 (21%), Positives = 84/184 (45%), Gaps = 13/184 (7%)
Query: 630 KKEYEHNKRLQDFKDCIRRQRLTQSKIK--ENRQQIVRARKYYDDYRVQLCAKMMRMRTR 687
K+E E +R + +D +R+RL + K+K E +++++AR+ + + + ++ + +
Sbjct: 548 KEEAEQLRRQKVEED--KRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 605
Query: 688 EEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAI 747
+ +K EE L +K + + A +K +E R + E ++ + Q E
Sbjct: 606 IDEKTEKAKEERLAEEKAK----KKAAAKKMEEVEARRKQEEEARRLRWLQQ-----EEE 656
Query: 748 SQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSR 807
+ HQEL ++K + Q + E + E+ Q+ ++ + + E ER
Sbjct: 657 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 716
Query: 808 LQLA 811
QLA
Sbjct: 717 RQLA 720
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 52.8 bits (125), Expect = 1e-06
Identities = 51/255 (20%), Positives = 119/255 (46%), Gaps = 35/255 (13%)
Query: 583 LSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEE----ALRRHDLLTTLVKKEYEHNKR 638
L K+ ++QI L+ + C+ + KK L+D I E + +L K + +H
Sbjct: 973 LKKLEEEQII----LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAM 1028
Query: 639 LQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKM----MRMRTREEMI--- 691
+ D ++ +RR+ + ++++ R+++ D +L A++ M++ +EE +
Sbjct: 1029 ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAA 1088
Query: 692 FKKLFEEGL--NIQKQRLRDLRNYAKE-------------KRDEQRRRHQDELDSMENYY 736
++ EE N+ +++R+L + E K ++Q+R +EL++++
Sbjct: 1089 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148
Query: 737 KDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFF 796
+D A QEL+++ + + L K E E +IQ+++ +Q +++
Sbjct: 1149 EDTLDSTAA-----QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAE 1203
Query: 797 RELEAERFRSRLQLA 811
+ + +R ++ L+ A
Sbjct: 1204 QLEQTKRVKANLEKA 1218
Score = 49.7 bits (117), Expect = 1e-05
Identities = 73/334 (21%), Positives = 133/334 (39%), Gaps = 50/334 (14%)
Query: 491 ELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLP 550
+ + K+Q+NI L E+ EE E + + K T E K+ + + L
Sbjct: 935 QAEKKKMQQNIQELE--EQLEEEESARQKLQLEKVTTEAKLK-KLEEEQIILEDQNCKLA 991
Query: 551 KPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKKK 610
K K + +++E + E+ +L+K+ + A + L++ RE + +++
Sbjct: 992 KEKKLLEDRIAEFTTNLTEEEE------KSKSLAKLKNKHEAMITDLEERLRREEKQRQE 1045
Query: 611 LQ--------------DEIEEALRR-HDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSK 655
L+ D+I E + +L L KKE E L ++ ++ + K
Sbjct: 1046 LEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK 1105
Query: 656 IKENRQQIVRARKYYDDYRVQL--CAKMMRMRTREEMIFKKLFEEGLN--IQKQRLRDLR 711
I+E QI ++ + R K R E K E+ L+ +Q LR R
Sbjct: 1106 IRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKR 1165
Query: 712 ----NYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHK 767
N K+ +E+ + H+ ++ M + LAE + Q + +KA + QTL
Sbjct: 1166 EQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT-KRVKANLEKAKQTLEN 1224
Query: 768 VKREL-----------------RSKMEKEIQQLQ 784
+ EL R K+E ++Q+LQ
Sbjct: 1225 ERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQ 1258
Score = 38.9 bits (89), Expect = 0.020
Identities = 50/260 (19%), Positives = 110/260 (42%), Gaps = 20/260 (7%)
Query: 571 EQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVK 630
++F L T+S + ++ + E EA + L +EEA+ + L L K
Sbjct: 1444 KKFDQLLAEEKTISAKYAEERDRAEA---EAREKETKALSLARALEEAMEQKAELERLNK 1500
Query: 631 KEYEHNKRLQDFKDCI--------RRQRLTQSKIKENRQQIVRAR---KYYDDYRVQLCA 679
+ + L KD + + +R + +++E + Q+ + +D +++L
Sbjct: 1501 QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV 1560
Query: 680 KMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQ--DELDSMENYYK 737
+ M+ + E + E+ +KQ +R +R E DE+++R +E K
Sbjct: 1561 NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLK 1620
Query: 738 DQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFR 797
D + + A + +K K QAQ +K +R + + + + +++ +
Sbjct: 1621 DLEAHIDSANKNRDEAIKQLRKLQAQ----MKDCMRELDDTRASREEILAQAKENEKKLK 1676
Query: 798 ELEAERFRSRLQLASFQYSK 817
+EAE + + +LA+ + +K
Sbjct: 1677 SMEAEMIQLQEELAAAERAK 1696
Score = 38.5 bits (88), Expect = 0.026
Identities = 38/170 (22%), Positives = 81/170 (47%), Gaps = 13/170 (7%)
Query: 647 RRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQR 706
R+Q+LT K+ + + + +R+ K + +R+E EE + +++++
Sbjct: 802 RQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQ 861
Query: 707 LRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLH 766
L A E R + Q +L + + ++Q E + E +EL+AR ++ Q L
Sbjct: 862 L------AAENRLTEMETLQSQLMAEKLQLQEQLQAETE-LCAEAEELRARLTAKKQELE 914
Query: 767 KVKRELRSKMEKEIQQLQDM------ITQNDDDVFFRELEAERFRSRLQL 810
++ +L +++E+E ++ Q + + QN ++ + E E R +LQL
Sbjct: 915 EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964
Score = 36.6 bits (83), Expect = 0.097
Identities = 90/483 (18%), Positives = 193/483 (39%), Gaps = 49/483 (10%)
Query: 357 QRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGT-- 414
+R + E++ D+ E+L +EL+ L S + +E N + +E+
Sbjct: 1123 ERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKT 1182
Query: 415 -----EETLSQHSDGIVEYGP-----KKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLE 464
+E +HS + E K+ + L ++ + V Q +
Sbjct: 1183 HEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGD 1242
Query: 465 RKRQRKPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRK 524
+ +RK E +++ Q + F E E R ++ + + L++ E + T + + ++ K
Sbjct: 1243 SEHKRKKVEAQLQELQVK-FNEG---ERVRTELADKVTKLQV-ELDNVTGLLSQSDS--K 1295
Query: 525 GTPECSQPWKIYSRKTTTQSL-----RGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVS 579
+ + S+ TQ L R L K ++ ++S + E+ +
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH-- 1353
Query: 580 GPTLSKMWKQQIAQVEQLKKE-----ACRENRS--KKKLQDEIEEALRRHDLLTTLVKKE 632
L K AQV +KK+ C E K+KLQ ++E +RH+ K
Sbjct: 1354 --NLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL 1411
Query: 633 YEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQ---LCAKMMRMRTREE 689
+ RLQ D + + +++ + + +K +D + + AK R R E
Sbjct: 1412 EKTKTRLQQELDDL---LVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE 1468
Query: 690 MIFKKLFEEGLNIQKQRLRDLRNYAK-EKRDEQRRRHQDELDSMENYYKDQFSLLAEAIS 748
++ + L++ + + A+ E+ ++Q R ++L S KD +
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS----KDDVGKSVHELE 1524
Query: 749 QEHQELKAREKSQAQTLHKVKRELRSKMEKEIQ---QLQDMITQNDDDVFFRELEAERFR 805
+ + L+ + + L +++ EL++ + +++ LQ M Q + D+ R+ ++E +
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKK 1584
Query: 806 SRL 808
+L
Sbjct: 1585 KQL 1587
Score = 34.3 bits (77), Expect = 0.48
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 10/61 (16%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIR 647
KQ Q+E+ ++EA R N S++KLQ E+E+A D + N+ + K+ +R
Sbjct: 1873 KQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAM----------NREVSSLKNKLR 1922
Query: 648 R 648
R
Sbjct: 1923 R 1923
Score = 30.4 bits (67), Expect = 7.0
Identities = 78/467 (16%), Positives = 182/467 (38%), Gaps = 47/467 (10%)
Query: 367 ELHDVSEKLSQRLSELDWM--LKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQHSDG 424
++ D+ +K+ + L+ +K L ++ + EE + + T+ L Q D
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424
Query: 425 IVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQ-AQA 483
++ + + ++ +K L+ K + + + RE + + A+A
Sbjct: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARA 1484
Query: 484 FTEAFERELRRHKVQENIGPLR---IHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKT 540
EA E++ ++ + + K++ + ++ E ++ + ++ KT
Sbjct: 1485 LEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ-----QVEEMKT 1539
Query: 541 TTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQI--------A 592
+ L L A K+ L M QF S+ K+Q+ A
Sbjct: 1540 QLEELEDELQATEDA---KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEA 1596
Query: 593 QVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQ-DFKDCIRR--- 648
++E +K+ ++KKL+ ++++ D + + ++LQ KDC+R
Sbjct: 1597 ELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDD 1656
Query: 649 ------QRLTQSKIKENRQQIVRAR--KYYDDYRVQLCAKMMRMRTREEMIFKKLFEEG- 699
+ L Q+K E + + + A + ++ AK + R+E+ + G
Sbjct: 1657 TRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGK 1716
Query: 700 --LNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSM---ENYYKDQFSL-------LAEAI 747
L ++++R + R E+ E+ + + + ++ N DQ + A+
Sbjct: 1717 GALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN 1776
Query: 748 SQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDV 794
Q+L+ + K L +++ ++SK + I L+ I Q ++ +
Sbjct: 1777 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQL 1823
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 52.8 bits (125), Expect = 1e-06
Identities = 95/486 (19%), Positives = 201/486 (41%), Gaps = 69/486 (14%)
Query: 325 PAQVQGPRTRKPPKGKRNENRATASSCNSPFPQRPRK--------RLTEQELHDVSEKLS 376
P G +T+K K + T+ C+SP + ++ +T +L++ E L
Sbjct: 38 PGIPAGAKTKKK-KTDSSPETTTSGGCHSPGDSQYQELAVALESSSVTISQLNENIESLK 96
Query: 377 QRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRPG 436
Q+ +++ L+ A +KT+++ E +E TL + Y K++
Sbjct: 97 QQKKQVEHQLEEA------KKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARH 150
Query: 437 LSMRRKP--PYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERE--- 491
K +SL + + ++Q + R + R+ Q + + +E
Sbjct: 151 FEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERAL 210
Query: 492 LRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPK 551
L H Q ++ + +E K +GE R + WK+ T + K
Sbjct: 211 LNAHVTQVTESLKQVQLERDEYAKHIKGERARWQ----ERMWKMSVEARTLKE-----EK 261
Query: 552 PNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKKKL 611
++ E SL L + ++ P ++ + VEQL+ EA + + L
Sbjct: 262 KRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSV-------VEQLQDEAKHLRQEVEGL 314
Query: 612 QDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYD 671
+ +++ + + L+ L K E +RLQ+ ++ +R Q + + +E
Sbjct: 315 EGKLQSQVENNQALSLLSK---EQKQRLQEQEEMLREQEAQRVREQE------------- 358
Query: 672 DYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDE--L 729
+LC + R+R ++ K L E+G ++KQ R + + +++E+R + Q++
Sbjct: 359 ----RLCEQNERLREQQ----KTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLW 410
Query: 730 DSMENYYKDQFSLLAE----AISQEHQELKAREKSQAQTLHKVKRELRS--KMEKEIQQL 783
D E +K + L + A+SQ H+ K + Q + + E +S ++E+++++L
Sbjct: 411 DQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQC-SFEDLNNEKKSALQLEQQVKEL 469
Query: 784 QDMITQ 789
Q+ + +
Sbjct: 470 QEKLDE 475
Score = 38.5 bits (88), Expect = 0.026
Identities = 56/266 (21%), Positives = 108/266 (40%), Gaps = 44/266 (16%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEE-----ALRRHDLLTTLVKKEYEHNKRLQDF 642
KQQ QVE +EA + N K Q E E L + DL TTL + ++
Sbjct: 96 KQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEES 155
Query: 643 KDCIRRQRLTQSKIKENR----------------------------QQIVRARKYYDDYR 674
KD R + + +I+E QQ ++ R + +
Sbjct: 156 KDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLNAHV 215
Query: 675 VQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLR---DLRNYAKEKRDEQRRRHQDE--L 729
Q+ + +++ + K + E Q++ + + R +EK+ + R + E L
Sbjct: 216 TQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSL 275
Query: 730 DSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKE-----IQQLQ 784
++N + SL A++ ++L+ K Q + ++ +L+S++E + + Q
Sbjct: 276 SELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQ 335
Query: 785 DMITQNDDDVFFRELEAERFRSRLQL 810
Q +++ RE EA+R R + +L
Sbjct: 336 KQRLQEQEEM-LREQEAQRVREQERL 360
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 52.4 bits (124), Expect = 2e-06
Identities = 71/329 (21%), Positives = 149/329 (45%), Gaps = 56/329 (17%)
Query: 496 KVQENIGPLRIHEKEEETEKIY------------RGEAVRKGTPEC-SQPWKIYSRKTTT 542
++ ENI L KEE+ +I+ + + PE + P K+ + T
Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDET 166
Query: 543 QSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEAC 602
LR L + + +V + +L L+ + L + ++ Q E+L+++
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRR------QEERLREQEERLREQEERLREQEE 220
Query: 603 RENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRL--QDFKDCIRRQRLTQSKIKENR 660
R +++L+++ E + + L ++ EH +RL Q+ + C + +RL + + + +
Sbjct: 221 RLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHE 280
Query: 661 QQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDE 720
Q+ +LC + R+R +EE + ++ EE L Q++RL + E
Sbjct: 281 QE------------ERLCEQEERLREQEERLCEQ--EERLREQEERLCE---------QE 317
Query: 721 QRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEI 780
+R R Q+E + Q E + +E ++L +E+ Q + ++RE ++ +E+
Sbjct: 318 ERLREQEERLCEQEKLPGQ-----ERLLEEVEKLLEQERRQEEQERLLERE---RLLEEV 369
Query: 781 QQL--QDMITQNDDDVFFREL--EAERFR 805
++L Q+ + Q D+ ++ +E E ER R
Sbjct: 370 EELLEQERLRQQDERLWQQETLQELERLR 398
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 52.4 bits (124), Expect = 2e-06
Identities = 56/263 (21%), Positives = 124/263 (47%), Gaps = 27/263 (10%)
Query: 534 KIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPL-------MLEQFPFLY--VSGPTLS 584
++Y T + L+ + + + + SE S + L LE+ FL V TL
Sbjct: 174 ELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233
Query: 585 K-MWKQQIAQVEQLKKEACREN---RSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQ 640
+ MW+Q+ EQ KK +E R +++L+++ + + + + K+ E K L+
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR 293
Query: 641 DFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGL 700
+ + +R Q+ K++E +Q+ + + ++ + +M +EE ++++ E+ +
Sbjct: 294 EQEKELREQK----KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ--EKQM 347
Query: 701 NIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKS 760
Q+Q++RD E +DE+ R ++ + E ++ + + QE + ++ REK
Sbjct: 348 REQEQKMRDQEERMWE-QDERLREKEERMREQEKMWEQEEKM------QEEERIREREKK 400
Query: 761 QAQTLHKVKRELRSKMEKEIQQL 783
+ + RE KM+K+ + +
Sbjct: 401 MREE-EETMREQEEKMQKQEENM 422
Score = 51.6 bits (122), Expect = 3e-06
Identities = 90/446 (20%), Positives = 185/446 (41%), Gaps = 49/446 (10%)
Query: 357 QRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEE 416
+R KRL EQE ++L ++ EL K L ++ ++ + +E+ EE EE
Sbjct: 279 RRQEKRLREQE-----KELREQEKELREQKK--LREQEEQMQEQEEKMWEQEEKMREQEE 331
Query: 417 TLSQHSDGIVEYGPKKSRPGLSMRRKPPY------RSHSLSPSPVNKHKQFHLERKRQRK 470
+ + + + E + MR + R + K + E K Q +
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 471 PRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKE-----EETEKIYRGEAVRKG 525
R + + + E+E + K +EN+ E + E+ EK++ E +++
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 526 TPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSK 585
+ W+ + + + G K + M+ E M EQ + K
Sbjct: 452 EEKI---WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ----MWEQEEKMRDQE---QK 501
Query: 586 MWKQQIA---QVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDF 642
MW Q+ Q E+L+++ R KK Q E E +R KK E K+ D
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQE--EKMREE-------KKTQEQEKKTWDQ 552
Query: 643 KDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNI 702
++ +R + + + K+ R++ R+ + + Q +MR +EE ++++ EE +
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQ----EEKMREQEEKMWEQ--EEKMQE 606
Query: 703 QKQRLRDLRNYAKEKRDEQRRRHQDEL--DSMENYYKDQFSLLAEAISQEHQELKAREKS 760
Q++++ + E+ +E + + Q+E+ + E + + + + QE K RE+
Sbjct: 607 QEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 761 Q-AQTLHKVKRELRSKMEKEIQQLQD 785
+ Q + RE KM+ + +++++
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMRE 692
Score = 45.8 bits (107), Expect = 2e-04
Identities = 90/451 (19%), Positives = 188/451 (41%), Gaps = 54/451 (11%)
Query: 358 RPRKRLTEQE--LHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTE 415
R +RL EQE + + EK+ ++ L K L ++ KE + K+ E++++ E
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQEKRLREQEKE-LREQEKELREQKKLREQEEQMQE-QE 316
Query: 416 ETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETD 475
E + + + + E K R + + KQ R++++K R+ +
Sbjct: 317 EKMWEQEEKMREQEEKMWRQEERLWEQ---------------EKQM---REQEQKMRDQE 358
Query: 476 VRQF-QAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAV------RKGTPE 528
R + Q + E ER + K+ E ++ E+ E EK R E K +
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 529 CSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWK 588
W+ ++ Q L K + M+ E + E+ KMW+
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE-QEEKIRDQEEMWGQEKKMWR 477
Query: 589 QQIA--QVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCI 646
Q+ Q +Q+ ++ + ++K+ D+ E + + L ++ E K Q ++ +
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ-EEKM 536
Query: 647 RRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQR 706
R ++ TQ + K+ Q + R+ ++ + +MR EEM+ ++ EE + Q+++
Sbjct: 537 REEKKTQEQEKKTWDQEEKMRE-----EERMREREKKMREEEEMMREQ--EEKMQEQEEK 589
Query: 707 LRDLRNYA---KEKRDEQRRR---------HQDELDSMENYYKDQFSLLAEAISQEHQEL 754
+R+ +EK EQ + Q+E D M+ +++ E QE +E
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE--QEEMMWEQEEKMQEQEEK 647
Query: 755 KAREKSQAQTLHKVKRELRSKMEKEIQQLQD 785
++ + + + RE KM+ + +++++
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMRE 678
Score = 39.7 bits (91), Expect = 0.011
Identities = 47/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIR 647
++ ++ V K+A R K +D + L R+ + +KK+ N LQ+
Sbjct: 144 QRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKK---NAELQEKLRLAE 200
Query: 648 RQRLT-QSKIKENRQQIVRARKYYDDYRVQLCAKMM-----RMRTREEMIFKKLFEEGLN 701
++ Q +KE ++++ RA+ + + M +R +E+ I K+ EE +
Sbjct: 201 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMW 258
Query: 702 IQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQ 761
Q++RLR+ +E+ ++ RR+ + L E ++Q L E QE + +E+ +
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQ-EKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317
Query: 762 AQTLHKVK-RELRSKMEKEIQQLQDMITQ 789
+ K RE KM ++ ++L + Q
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
>gi|148746218 TAO kinase 3 [Homo sapiens]
Length = 898
Score = 52.4 bits (124), Expect = 2e-06
Identities = 54/218 (24%), Positives = 107/218 (49%), Gaps = 31/218 (14%)
Query: 596 QLKKEACRENRSKKKLQDEIEEA-LRRHDLLTTLVKKEYEHNKRLQDFK-DCIRRQRLTQ 653
+++++ RE +KK+ Q E+E A L RHD T + EY LQ + D IR Q T+
Sbjct: 625 EVEQQNIREELNKKRTQKEMEHAMLIRHDESTR--ELEYRQLHTLQKLRMDLIRLQHQTE 682
Query: 654 --SKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLR 711
++++ N++ R R+ + + ++L + ++ E I KK F++ +Q ++ + L+
Sbjct: 683 LENQLEYNKR---RERELHRKHVMELRQQPKNLKAMEMQI-KKQFQDTCKVQTKQYKALK 738
Query: 712 NYA-------------KEKRDEQRRR----HQDELDSMENYYKDQFSLLAEAISQEHQEL 754
N+ K +DEQ R+ + S+ Q L EA E Q L
Sbjct: 739 NHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQAL 798
Query: 755 KAREKSQAQTLH----KVKRELRSKMEKEIQQLQDMIT 788
+ + + + + L+ K+K + ++ E+E+Q+L+ ++
Sbjct: 799 RLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVS 836
Score = 49.7 bits (117), Expect = 1e-05
Identities = 62/273 (22%), Positives = 122/273 (44%), Gaps = 42/273 (15%)
Query: 583 LSKMWKQQIAQVEQLKKEACRENRS---------KKKLQDEIEEALRRHDLLTTLVKKEY 633
L K+ K+Q+A +E+ K A + + KK L +E +++ + +K+E
Sbjct: 508 LEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEM 567
Query: 634 --EHNKRLQDFKDCI--RRQRLTQSKIKENRQQIVRARKYYDD----YRVQLCAK----- 680
+H+ ++ ++ I ++ L ++ +E + + R YYD ++ ++ K
Sbjct: 568 NEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVE 627
Query: 681 -------MMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSME 733
+ + RT++EM L + ++ R L K + D R +HQ EL++
Sbjct: 628 QQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQL 687
Query: 734 NYYKDQFSLL----AEAISQEHQELKARE---KSQAQTLHKVKRELRSKMEKEIQQLQDM 786
Y K + L + Q+ + LKA E K Q Q KV ++K K ++ Q
Sbjct: 688 EYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKV----QTKQYKALKNHQLE 743
Query: 787 IT-QNDDDVFFRELEAERFRSRLQLASFQYSKS 818
+T +N+ + L+ E+ R +L + + QY +S
Sbjct: 744 VTPKNEHKTILKTLKDEQTR-KLAILAEQYEQS 775
Score = 36.6 bits (83), Expect = 0.097
Identities = 31/178 (17%), Positives = 83/178 (46%), Gaps = 10/178 (5%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKD-CI 646
+QQ ++ ++ + ++ + K+Q + +AL+ H L T + EH L+ KD
Sbjct: 706 RQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVT---PKNEHKTILKTLKDEQT 762
Query: 647 RRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQR 706
R+ + + +++ +++ ++ D + + +R++ ++EM ++ + +Q +
Sbjct: 763 RKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEA 822
Query: 707 LRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQT 764
+ E+R RR H +E +++ + L + S+ + L R++ + +T
Sbjct: 823 QHERELQKLEQRVSLRRAH------LEQKIEEELAALQKERSERIKNLLERQEREIET 874
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/226 (24%), Positives = 107/226 (47%), Gaps = 30/226 (13%)
Query: 589 QQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDF------ 642
+Q+ Q+E+ KKE ++++K D E A R ++ L+K YE +R++D
Sbjct: 672 KQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEI--PLIKSAYEE-QRIKDMDLWEQQ 728
Query: 643 -KDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLN 701
++ I +L + K E++ ++ R + D + +MR++ + ++ EE L
Sbjct: 729 EEERITTMQLEREKALEHKNRMSRMLEDRDLF-------VMRLKAARQSVY----EEKLK 777
Query: 702 IQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQ 761
++RL + R+ E+R QR+ + YY+++ E E Q LK RE+ +
Sbjct: 778 QFEERLAEERHNRLEERKRQRKE-----ERRITYYREKEE--EEQRRAEEQMLKEREERE 830
Query: 762 AQTLHKVKRELRSKME--KEIQQLQDMITQNDDDVFFRELEAERFR 805
K + ELR E K++++++ Q + ++ RE E R
Sbjct: 831 RAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEER 876
Score = 37.4 bits (85), Expect = 0.057
Identities = 62/346 (17%), Positives = 142/346 (41%), Gaps = 42/346 (12%)
Query: 415 EETLSQHSDGIVEY---GPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQ-RK 470
+E QH + Y K+ + L+ R+ R L + + K+ +R+ + +K
Sbjct: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
Query: 471 PRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRG---------EA 521
R+ + + + +A ER L+ H E I + E+ E+ +K G E
Sbjct: 604 VRKAEEERLRQEAKEREKERILQEH---EQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
Query: 522 VRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPM--KVSEHSLLPLMLEQFPFLYVS 579
+ + P+ ++ + + L+ L K + + +PL+ + +
Sbjct: 661 LEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK 720
Query: 580 GPTLSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVK--KEYEHNK 637
L + +++ QL++E E++++ + L DL +K ++ + +
Sbjct: 721 DMDLWEQQEEERITTMQLEREKALEHKNR------MSRMLEDRDLFVMRLKAARQSVYEE 774
Query: 638 RLQDFKDCIRRQRLTQSKIKENRQQIVRARKYY----DDYRVQLCAKMMRMRTREEMIFK 693
+L+ F++ + +R + + ++ +++ R YY ++ + + +M++ R E +
Sbjct: 775 KLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAER 834
Query: 694 KLFEEGLNI------------QKQRLRDLRNYAKEKRDEQRRRHQD 727
EE L +K+R R+L +E+R E+ RR D
Sbjct: 835 AKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGD 880
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 51.2 bits (121), Expect = 4e-06
Identities = 53/230 (23%), Positives = 105/230 (45%), Gaps = 27/230 (11%)
Query: 591 IAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQR 650
+ Q++QL+K KL+ E EA R K+E E KR ++ +RRQ
Sbjct: 717 LEQLQQLEKAKAA------KLEQERREAEMR-------AKREEEERKRQEE----LRRQ- 758
Query: 651 LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDL 710
Q +I +Q+ R R+ ++ + + +R + +E+ ++ EE ++Q+ L
Sbjct: 759 --QEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE--EERQQQEEAL 814
Query: 711 RNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKR 770
R + +R+E+ RR Q+EL + +++ E + +E + R + +A L +
Sbjct: 815 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 874
Query: 771 ELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPS 820
E R + E E+Q+ ++++ Q ++ R + + Q K PS
Sbjct: 875 E-RKRKELEVQRQKELMRQRQQ----QQEALRRLQQQQQQQQLAQMKLPS 919
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/209 (22%), Positives = 100/209 (47%), Gaps = 24/209 (11%)
Query: 583 LSKMWKQQIAQVEQLKKEA---CRENRSKKKLQDEI----EEALRRHDLLTTLVKKEYEH 635
L ++ K + A++EQ ++EA + ++K Q+E+ EE LRR ++E E
Sbjct: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 779
Query: 636 NKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKL 695
+R Q+ + +RRQR + ++ R++ R ++ R++ + R ++E + +K
Sbjct: 780 ARRKQE--EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ 837
Query: 696 FEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELK 755
EE +A+E+ + QRR ++ L E + L E ++ +EL+
Sbjct: 838 EEEA-----------AKWAREEEEAQRRLEENRLRMEE----EAARLRHEEEERKRKELE 882
Query: 756 AREKSQAQTLHKVKRELRSKMEKEIQQLQ 784
+ + + + ++E +++++ QQ Q
Sbjct: 883 VQRQKELMRQRQQQQEALRRLQQQQQQQQ 911
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/226 (20%), Positives = 104/226 (46%), Gaps = 27/226 (11%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKL-QDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCI 646
++Q ++ + ++E R+ R +++L + + EEALRR ++++ E +R Q ++ +
Sbjct: 756 RRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ-EEAL 814
Query: 647 RRQRLTQSKIKENRQQIVRARKY-----------------YDDYRVQLCAKMMRMRTREE 689
RR + + +E R+Q RK ++ R+++ + R+R EE
Sbjct: 815 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 874
Query: 690 MIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQ 749
+K E + QK+ +R + + R Q+++ Q +L M+ + + +
Sbjct: 875 ERKRKELE--VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
Query: 750 EHQ------ELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQ 789
+ Q E++ E+ + + L + +R + ++ K +QQ Q Q
Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 978
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 51.2 bits (121), Expect = 4e-06
Identities = 53/230 (23%), Positives = 105/230 (45%), Gaps = 27/230 (11%)
Query: 591 IAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQR 650
+ Q++QL+K KL+ E EA R K+E E KR ++ +RRQ
Sbjct: 744 LEQLQQLEKAKAA------KLEQERREAEMR-------AKREEEERKRQEE----LRRQ- 785
Query: 651 LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDL 710
Q +I +Q+ R R+ ++ + + +R + +E+ ++ EE ++Q+ L
Sbjct: 786 --QEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE--EERQQQEEAL 841
Query: 711 RNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKR 770
R + +R+E+ RR Q+EL + +++ E + +E + R + +A L +
Sbjct: 842 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
Query: 771 ELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPS 820
E R + E E+Q+ ++++ Q ++ R + + Q K PS
Sbjct: 902 E-RKRKELEVQRQKELMRQRQQ----QQEALRRLQQQQQQQQLAQMKLPS 946
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/209 (22%), Positives = 100/209 (47%), Gaps = 24/209 (11%)
Query: 583 LSKMWKQQIAQVEQLKKEA---CRENRSKKKLQDEI----EEALRRHDLLTTLVKKEYEH 635
L ++ K + A++EQ ++EA + ++K Q+E+ EE LRR ++E E
Sbjct: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 806
Query: 636 NKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKL 695
+R Q+ + +RRQR + ++ R++ R ++ R++ + R ++E + +K
Sbjct: 807 ARRKQE--EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ 864
Query: 696 FEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELK 755
EE +A+E+ + QRR ++ L E + L E ++ +EL+
Sbjct: 865 EEEA-----------AKWAREEEEAQRRLEENRLRMEE----EAARLRHEEEERKRKELE 909
Query: 756 AREKSQAQTLHKVKRELRSKMEKEIQQLQ 784
+ + + + ++E +++++ QQ Q
Sbjct: 910 VQRQKELMRQRQQQQEALRRLQQQQQQQQ 938
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/226 (20%), Positives = 104/226 (46%), Gaps = 27/226 (11%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKL-QDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCI 646
++Q ++ + ++E R+ R +++L + + EEALRR ++++ E +R Q ++ +
Sbjct: 783 RRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ-EEAL 841
Query: 647 RRQRLTQSKIKENRQQIVRARKY-----------------YDDYRVQLCAKMMRMRTREE 689
RR + + +E R+Q RK ++ R+++ + R+R EE
Sbjct: 842 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
Query: 690 MIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQ 749
+K E + QK+ +R + + R Q+++ Q +L M+ + + +
Sbjct: 902 ERKRKELE--VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
Query: 750 EHQ------ELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQ 789
+ Q E++ E+ + + L + +R + ++ K +QQ Q Q
Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 1005
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 51.2 bits (121), Expect = 4e-06
Identities = 53/230 (23%), Positives = 105/230 (45%), Gaps = 27/230 (11%)
Query: 591 IAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQR 650
+ Q++QL+K KL+ E EA R K+E E KR ++ +RRQ
Sbjct: 723 LEQLQQLEKAKAA------KLEQERREAEMR-------AKREEEERKRQEE----LRRQ- 764
Query: 651 LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDL 710
Q +I +Q+ R R+ ++ + + +R + +E+ ++ EE ++Q+ L
Sbjct: 765 --QEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE--EERQQQEEAL 820
Query: 711 RNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKR 770
R + +R+E+ RR Q+EL + +++ E + +E + R + +A L +
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Query: 771 ELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPS 820
E R + E E+Q+ ++++ Q ++ R + + Q K PS
Sbjct: 881 E-RKRKELEVQRQKELMRQRQQ----QQEALRRLQQQQQQQQLAQMKLPS 925
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/209 (22%), Positives = 100/209 (47%), Gaps = 24/209 (11%)
Query: 583 LSKMWKQQIAQVEQLKKEA---CRENRSKKKLQDEI----EEALRRHDLLTTLVKKEYEH 635
L ++ K + A++EQ ++EA + ++K Q+E+ EE LRR ++E E
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 636 NKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKL 695
+R Q+ + +RRQR + ++ R++ R ++ R++ + R ++E + +K
Sbjct: 786 ARRKQE--EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ 843
Query: 696 FEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELK 755
EE +A+E+ + QRR ++ L E + L E ++ +EL+
Sbjct: 844 EEEA-----------AKWAREEEEAQRRLEENRLRMEE----EAARLRHEEEERKRKELE 888
Query: 756 AREKSQAQTLHKVKRELRSKMEKEIQQLQ 784
+ + + + ++E +++++ QQ Q
Sbjct: 889 VQRQKELMRQRQQQQEALRRLQQQQQQQQ 917
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/226 (20%), Positives = 104/226 (46%), Gaps = 27/226 (11%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKL-QDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCI 646
++Q ++ + ++E R+ R +++L + + EEALRR ++++ E +R Q ++ +
Sbjct: 762 RRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ-EEAL 820
Query: 647 RRQRLTQSKIKENRQQIVRARKY-----------------YDDYRVQLCAKMMRMRTREE 689
RR + + +E R+Q RK ++ R+++ + R+R EE
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Query: 690 MIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQ 749
+K E + QK+ +R + + R Q+++ Q +L M+ + + +
Sbjct: 881 ERKRKELE--VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 750 EHQ------ELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQ 789
+ Q E++ E+ + + L + +R + ++ K +QQ Q Q
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 51.2 bits (121), Expect = 4e-06
Identities = 53/230 (23%), Positives = 105/230 (45%), Gaps = 27/230 (11%)
Query: 591 IAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQR 650
+ Q++QL+K KL+ E EA R K+E E KR ++ +RRQ
Sbjct: 723 LEQLQQLEKAKAA------KLEQERREAEMR-------AKREEEERKRQEE----LRRQ- 764
Query: 651 LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDL 710
Q +I +Q+ R R+ ++ + + +R + +E+ ++ EE ++Q+ L
Sbjct: 765 --QEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE--EERQQQEEAL 820
Query: 711 RNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKR 770
R + +R+E+ RR Q+EL + +++ E + +E + R + +A L +
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Query: 771 ELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPS 820
E R + E E+Q+ ++++ Q ++ R + + Q K PS
Sbjct: 881 E-RKRKELEVQRQKELMRQRQQ----QQEALRRLQQQQQQQQLAQMKLPS 925
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/209 (22%), Positives = 100/209 (47%), Gaps = 24/209 (11%)
Query: 583 LSKMWKQQIAQVEQLKKEA---CRENRSKKKLQDEI----EEALRRHDLLTTLVKKEYEH 635
L ++ K + A++EQ ++EA + ++K Q+E+ EE LRR ++E E
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 636 NKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKL 695
+R Q+ + +RRQR + ++ R++ R ++ R++ + R ++E + +K
Sbjct: 786 ARRKQE--EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ 843
Query: 696 FEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELK 755
EE +A+E+ + QRR ++ L E + L E ++ +EL+
Sbjct: 844 EEEA-----------AKWAREEEEAQRRLEENRLRMEE----EAARLRHEEEERKRKELE 888
Query: 756 AREKSQAQTLHKVKRELRSKMEKEIQQLQ 784
+ + + + ++E +++++ QQ Q
Sbjct: 889 VQRQKELMRQRQQQQEALRRLQQQQQQQQ 917
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/226 (20%), Positives = 104/226 (46%), Gaps = 27/226 (11%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKL-QDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCI 646
++Q ++ + ++E R+ R +++L + + EEALRR ++++ E +R Q ++ +
Sbjct: 762 RRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ-EEAL 820
Query: 647 RRQRLTQSKIKENRQQIVRARKY-----------------YDDYRVQLCAKMMRMRTREE 689
RR + + +E R+Q RK ++ R+++ + R+R EE
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Query: 690 MIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQ 749
+K E + QK+ +R + + R Q+++ Q +L M+ + + +
Sbjct: 881 ERKRKELE--VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 750 EHQ------ELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQ 789
+ Q E++ E+ + + L + +R + ++ K +QQ Q Q
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
Length = 1133
Score = 51.2 bits (121), Expect = 4e-06
Identities = 77/415 (18%), Positives = 169/415 (40%), Gaps = 56/415 (13%)
Query: 357 QRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTG-----NEEVE 411
++ R LT Q ++ ++ E++ + + + + DH+E+ + EV+
Sbjct: 665 EQARAELTAQHQRRLAAIAQEKDQEMERLRELQRASILDMRRDHEEQLQRLKLLKDREVD 724
Query: 412 DGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKP 471
T T S + + +K L H LS H ER+ +
Sbjct: 725 AATSATSHTRSLNSIIHQMEKFSSSL----------HELSSRVEASHLTTSQERELGIRQ 774
Query: 472 RETDVRQFQAQAFTEAFERELRRHKVQENIGPL--RIHEKEEETEKIYRGEAVRKGTPEC 529
R+ +R Q + + + E R + QE IG + R++E+ E+
Sbjct: 775 RDEQLRALQERLGQQQRDMEEERSRQQEVIGKMEARLNEQSRLLEQ-------------- 820
Query: 530 SQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVS------EHSLLPLMLEQFPFLYVSGP-- 581
+ W++ + ++ +S++ L + K +++ E + L+ EQ + G
Sbjct: 821 -ERWRVTAEQSKAESMQRALEEQRKVTAQQMAMERAELERAKSALLEEQKSVMLKCGEER 879
Query: 582 -TLSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQ 640
L+ W + AQ ++L KE R++++ + ++ +R L +L K++ E R
Sbjct: 880 RRLAAEWAEFSAQ-QKLSKE-----RAEREAERALQVDTQREGTLISLAKEQAELKIRAS 933
Query: 641 DFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGL 700
+ + ++ ++ +++ RQ++ ++ R+ A +++R E K+ E
Sbjct: 934 ELRAEEKQLAAERAALEQERQELRLEKE-----RINATALRVKLRAEEVESMSKVASEKY 988
Query: 701 NIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELK 755
++ LR+ A++ + EQ+ R Q E K + + E +S Q L+
Sbjct: 989 EEGERALRE----AQQVQAEQQARLQAVQQQQERLRKQEQHMHQEHLSLAQQRLQ 1039
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 50.4 bits (119), Expect = 6e-06
Identities = 48/235 (20%), Positives = 116/235 (49%), Gaps = 21/235 (8%)
Query: 585 KMWKQQIAQVEQLKKEACREN---RSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQD 641
KMW+Q+ EQ +K +E+ R ++K++++ E+ + + + +K E ++++Q+
Sbjct: 326 KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
Query: 642 FKDCIRRQRLTQSKIKENRQQIV-RARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGL 700
++ + RQ + +E RQ+ + R K + ++ + M +EE I + EE +
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI--RELEEMM 443
Query: 701 NIQKQRLRDLRNYAKEK------RDEQRRRHQDELDSMENYYKDQFSLLA---------E 745
Q+++LR++ +E+ ++E+ +R ++++ E Q LL E
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Query: 746 AISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELE 800
+ ++ +++ +E+ + K++R+ E+E++ Q + +V +ELE
Sbjct: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
Score = 45.4 bits (106), Expect = 2e-04
Identities = 83/425 (19%), Positives = 173/425 (40%), Gaps = 85/425 (20%)
Query: 455 VNK-HKQFHLERKRQRKPRE---TDVRQFQAQAFTEAFERELRR---------------- 494
+NK +Q + K KPRE D + FQ E RR
Sbjct: 36 INKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESED 95
Query: 495 -HKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSL----RGGL 549
+ +E++ + ++E + V+K + E +K K ++ R +
Sbjct: 96 SKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVI 155
Query: 550 PKP----NKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACREN 605
KP + K E+SLL L F G + K+ K++ A +L + +
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLH-FDHAVRMGTYIEKLTKERDAPSLELYRNTITDE 214
Query: 606 RSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLT------------- 652
K+K E++E LR L K E + N ++D K + R +L
Sbjct: 215 ELKEK-NAELQEKLR----LVESEKSEIQLN--VKDLKRKLERAQLLLPQQQLQVEADRL 267
Query: 653 -----------QSKIKENR----------QQIVRARKYYDDYRVQLCAKMMRMRTREEMI 691
Q++++EN +++ R + + ++C + +++R +EE +
Sbjct: 268 GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKM 327
Query: 692 FKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDE--LDSMENYYKDQFSLLAEAISQ 749
+++ EE ++ Q++++R+ + K R E++ R Q+E + E ++ + E I +
Sbjct: 328 WRQ--EEKMHEQEEKIREQED--KMWRQEEKIREQEEKIREQEEKMWRQE-----EKIRE 378
Query: 750 EHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQ 809
+ ++++ +E+ + K++ + + EK +Q + M + D RE E E +R +
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM---REQDEKIREQEEEMWRQEEK 435
Query: 810 LASFQ 814
+ +
Sbjct: 436 IRELE 440
Score = 39.7 bits (91), Expect = 0.011
Identities = 45/219 (20%), Positives = 104/219 (47%), Gaps = 18/219 (8%)
Query: 585 KMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKD 644
+MW+Q+ EQ +K + R +KK++++ E+ + + + +K E + +QD ++
Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 645 CIR----RQRLTQSKIKENRQQIVRARKYYDDY------RVQLCAKMMRMRTREEMIFK- 693
+R + + + K++E ++I R + + + +L + ++ +EE +++
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ 508
Query: 694 --KLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEH 751
K++E+ +Q+Q + R K + E R Q+E + + + Q+
Sbjct: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKA 568
Query: 752 QEL-KAREKSQAQTLHK----VKRELRSKMEKEIQQLQD 785
+ L A +S +Q L ++ EL+S+ + +QQ QD
Sbjct: 569 ELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQD 607
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 50.4 bits (119), Expect = 6e-06
Identities = 48/235 (20%), Positives = 116/235 (49%), Gaps = 21/235 (8%)
Query: 585 KMWKQQIAQVEQLKKEACREN---RSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQD 641
KMW+Q+ EQ +K +E+ R ++K++++ E+ + + + +K E ++++Q+
Sbjct: 326 KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
Query: 642 FKDCIRRQRLTQSKIKENRQQIV-RARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGL 700
++ + RQ + +E RQ+ + R K + ++ + M +EE I + EE +
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI--RELEEMM 443
Query: 701 NIQKQRLRDLRNYAKEK------RDEQRRRHQDELDSMENYYKDQFSLLA---------E 745
Q+++LR++ +E+ ++E+ +R ++++ E Q LL E
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Query: 746 AISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELE 800
+ ++ +++ +E+ + K++R+ E+E++ Q + +V +ELE
Sbjct: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
Score = 45.1 bits (105), Expect = 3e-04
Identities = 83/425 (19%), Positives = 173/425 (40%), Gaps = 85/425 (20%)
Query: 455 VNK-HKQFHLERKRQRKPRE---TDVRQFQAQAFTEAFERELRR---------------- 494
+NK +Q + K KPRE D + FQ E RR
Sbjct: 36 INKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESED 95
Query: 495 -HKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSL----RGGL 549
+ +E++ + ++E + V+K + E +K K ++ R +
Sbjct: 96 SKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVI 155
Query: 550 PKP----NKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACREN 605
KP + K E+SLL L F G + K+ K++ A +L + +
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLH-FDHAVRMGTYIEKLTKERDALSLELYRNTITDE 214
Query: 606 RSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLT------------- 652
K+K E++E LR L K E + N ++D K + R +L
Sbjct: 215 ELKEK-NAELQEKLR----LVESEKSEIQLN--VKDLKRKLERAQLLLPQQQLQVEADRL 267
Query: 653 -----------QSKIKENR----------QQIVRARKYYDDYRVQLCAKMMRMRTREEMI 691
Q++++EN +++ R + + ++C + +++R +EE +
Sbjct: 268 GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKM 327
Query: 692 FKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDE--LDSMENYYKDQFSLLAEAISQ 749
+++ EE ++ Q++++R+ + K R E++ R Q+E + E ++ + E I +
Sbjct: 328 WRQ--EEKMHEQEEKIREQED--KMWRQEEKIREQEEKIREQEEKMWRQE-----EKIRE 378
Query: 750 EHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQ 809
+ ++++ +E+ + K++ + + EK +Q + M + D RE E E +R +
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM---REQDEKIREQEEEMWRQEEK 435
Query: 810 LASFQ 814
+ +
Sbjct: 436 IRELE 440
Score = 39.7 bits (91), Expect = 0.011
Identities = 45/219 (20%), Positives = 104/219 (47%), Gaps = 18/219 (8%)
Query: 585 KMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKD 644
+MW+Q+ EQ +K + R +KK++++ E+ + + + +K E + +QD ++
Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 645 CIR----RQRLTQSKIKENRQQIVRARKYYDDY------RVQLCAKMMRMRTREEMIFK- 693
+R + + + K++E ++I R + + + +L + ++ +EE +++
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ 508
Query: 694 --KLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEH 751
K++E+ +Q+Q + R K + E R Q+E + + + Q+
Sbjct: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKA 568
Query: 752 QEL-KAREKSQAQTLHK----VKRELRSKMEKEIQQLQD 785
+ L A +S +Q L ++ EL+S+ + +QQ QD
Sbjct: 569 ELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQD 607
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 50.4 bits (119), Expect = 6e-06
Identities = 72/369 (19%), Positives = 155/369 (42%), Gaps = 45/369 (12%)
Query: 463 LERKRQRKPRETDVRQFQAQAFTEAFER--ELR------RHKVQENIGPLRIH-EKEEET 513
+ERK Q+ E ++ Q QA TE F E+R + +++E + L E+EEE
Sbjct: 878 MERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEER 937
Query: 514 EKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQF 573
+I + E + ++ + Q L+ L K +K E +L L +
Sbjct: 938 NQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ--LEKVTAEAKIKKMEEEILLLEDQNS 995
Query: 574 PFLYVSGPTLSKMWK--QQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKK 631
F+ ++ + Q+A+ E+ K + ++ + ++EE L++ + ++
Sbjct: 996 KFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEK----TRQ 1051
Query: 632 EYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRM-----RT 686
E E KR D + + + QI + D+ ++QL K + R
Sbjct: 1052 ELEKAKRKLD------------GETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG 1099
Query: 687 REEMIFKKLFEEGLNIQKQRLRDLRN------YAKEKRDEQRRRHQDELDSMENYYKDQF 740
+E + K + + + ++ +L+ ++ K ++Q+R +EL++++ +D
Sbjct: 1100 DDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
Query: 741 SLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELE 800
A QEL+ + + + L K E E +IQ ++ +++ + +
Sbjct: 1160 DTTAA-----QQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQ 1214
Query: 801 AERFRSRLQ 809
A+RF++ L+
Sbjct: 1215 AKRFKANLE 1223
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/172 (23%), Positives = 85/172 (49%), Gaps = 17/172 (9%)
Query: 647 RRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQR 706
++Q+L+ K+ + +++ +RV K + TR+E + EE L +++++
Sbjct: 809 KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ 868
Query: 707 LRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLH 766
+ + + +E R+HQ L+ +N +Q E + E +E++AR ++ Q L
Sbjct: 869 TK-----VEGELEEMERKHQQLLEE-KNILAEQLQAETELFA-EAEEMRARLAAKKQELE 921
Query: 767 KVKRELRSKMEKEIQQLQDMITQND--------DDVFFRELEAERFRSRLQL 810
++ +L S++E+E ++ Q I QN+ D+ + E E R +LQL
Sbjct: 922 EILHDLESRVEEEEERNQ--ILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL 971
Score = 37.0 bits (84), Expect = 0.074
Identities = 51/243 (20%), Positives = 108/243 (44%), Gaps = 25/243 (10%)
Query: 589 QQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRR 648
+Q +++ +E + + K++ E+EE R+H L++++ ++LQ +
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQ---QLLEEKNILAEQLQAETELFAE 905
Query: 649 QRLTQSKIKENRQQI------VRARKYYDDYRVQLCA-KMMRMRTREEMIFKKLFEEGLN 701
++++ +Q++ + +R ++ R Q+ + +M+ + + ++L EE
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 702 IQKQRLRDLRNYAKEKR--------DEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQE 753
QK +L + AK K+ ++Q + E ME+ + S LAE +
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 754 LKAREK-----SQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRL 808
K R K S + K + + R ++EK ++L T D + EL+A+ +L
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI--AELQAQIDELKL 1083
Query: 809 QLA 811
QLA
Sbjct: 1084 QLA 1086
Score = 32.3 bits (72), Expect = 1.8
Identities = 50/249 (20%), Positives = 107/249 (42%), Gaps = 30/249 (12%)
Query: 593 QVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLT 652
+V +LKK E ++ + +I++ +RH + ++ E KR + + ++ T
Sbjct: 1175 EVAELKKALEEETKNHEA---QIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET 1231
Query: 653 QSKIKENRQQIVRARKYYDDY-RVQLCAKMMRMRTRE---EMIFKKLFEEGLNIQKQRLR 708
+K ++++ K ++ R +L A++ + + + + +L E+ +Q +
Sbjct: 1232 DNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL-- 1289
Query: 709 DLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAR------EKSQA 762
D + E+ +++ + + S+E+ +D LL E Q+ L +R EK+
Sbjct: 1290 DNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK-LNLSSRIRQLEEEKNSL 1348
Query: 763 QTLHKVKRELRSKMEKEIQQLQDMITQN----DDDVFFRE----------LEAERFRSRL 808
Q + + E R +EK++ LQ + DDD+ E +AE RL
Sbjct: 1349 QEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRL 1408
Query: 809 QLASFQYSK 817
+ + Y K
Sbjct: 1409 EEKALAYDK 1417
Score = 32.3 bits (72), Expect = 1.8
Identities = 15/39 (38%), Positives = 27/39 (69%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLT 626
KQ Q+E+ ++EA R N S++KLQ E+++A ++ L+
Sbjct: 1880 KQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLS 1918
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 50.4 bits (119), Expect = 6e-06
Identities = 91/468 (19%), Positives = 191/468 (40%), Gaps = 90/468 (19%)
Query: 364 TEQELHDVSEKLSQRLSELDWMLK--SALGDRIKEKTDHKEENTGNEEVEDGTEETLSQH 421
T++++H+ E + +++L +K + G+ ++E+ + K E EE+E
Sbjct: 369 TKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKE-KSERAAFEELEKALSTAQKT- 426
Query: 422 SDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQ------RKPRETD 475
+++R L ++ + Q L R +Q +K E
Sbjct: 427 ---------EEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQ 477
Query: 476 VRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKE-EETEKIYRGEAVRKGTPECSQPWK 534
+ + Q + E+EL R K QE L+ E+E +E K+ A+ K S+ K
Sbjct: 478 IAKLQ-----KLHEKELAR-KEQELTKKLQTREREFQEQMKV----ALEKSQ---SEYLK 524
Query: 535 IYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQV 594
I K +SL + K + SE+ L L E ++ ++ +I ++
Sbjct: 525 ISQEKEQQESLALEELELQKKAILTESENKLRDLQQE------------AETYRTRILEL 572
Query: 595 EQLKKEACRENRSKKK-LQDEIEEALRRHDL-LTTLVKKEYEHNKRLQDFKDCIRRQRLT 652
E +++ +EN+++ K L +E +H+ +T +V+K + L+ +D + ++L
Sbjct: 573 ESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 632
Query: 653 -------------QSKIKENRQQIVRARK-----YYDDYRVQLCAKMMRMRTREEMIFKK 694
+ K ++ ++ +++ ++ + ++ + K+ +T E + +
Sbjct: 633 VLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSE 692
Query: 695 L---------FEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSM-----------EN 734
L EE L++ K + ++ + K DEQ+ HQ ++DS+ E
Sbjct: 693 LSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEK 752
Query: 735 YYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQ 782
KDQ + L + + + LK + +KR E E+QQ
Sbjct: 753 ALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRS-----EGELQQ 795
Score = 48.1 bits (113), Expect = 3e-05
Identities = 86/481 (17%), Positives = 187/481 (38%), Gaps = 49/481 (10%)
Query: 361 KRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGN--------EEVED 412
KR EQ++ + ++L ++ E + K + E +E + VE
Sbjct: 1641 KRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVES 1700
Query: 413 GTEETL--SQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRK 470
ETL + + + Y ++ +K S+ + + ++ L+R Q K
Sbjct: 1701 SQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKL-LQRVGQEK 1759
Query: 471 PRET----DVRQFQAQAFTEAFERELRRHKVQENIGPLR--IHEKEEETEKIYRGEAVRK 524
++R + + E ++H+ Q IG L+ + EK ++ I ++
Sbjct: 1760 EETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKE 1819
Query: 525 GTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLS 584
G Q Q+L K + K +L +++ V +
Sbjct: 1820 GGKNNIQ---------AKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVH 1870
Query: 585 KMWKQQI-AQVEQLKKEACRENRSK--KKLQDEIEEALRRHDLLTTLVKK-EYEHN---- 636
++ +++ ++ E+L+ + R+K + L++ EE + H + L+ E +HN
Sbjct: 1871 RVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEF 1930
Query: 637 -------KRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMR-MRTRE 688
++ + K+ +R Q+ + KE++Q++ +K YD R + + + +
Sbjct: 1931 KLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKH 1990
Query: 689 EMIFKKLFEEGLNIQKQRLRDLR-------NYAKEKRDEQRRRHQDELDSMENYYKDQFS 741
K+L E Q+ ++L N A+E E HQ+E + + ++
Sbjct: 1991 NSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDD 2050
Query: 742 LLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEA 801
L + + L ARE+ + ++ +L +K Q+L+ +D+V EL+
Sbjct: 2051 DLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQT 2110
Query: 802 E 802
+
Sbjct: 2111 Q 2111
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/218 (19%), Positives = 101/218 (46%), Gaps = 13/218 (5%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKK-EYEHNKRLQDFKDCI 646
KQ Q E+L+++ + +S++ +E+E+AL +K + E +++++ +
Sbjct: 392 KQMTTQGEELREQ---KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS 448
Query: 647 RRQRLT-QSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQ 705
+R++ Q ++ +Q++V K + ++ AK+ ++ +E ++ + L +++
Sbjct: 449 EEERISLQQELSRVKQEVVDVMKKSSEEQI---AKLQKLHEKELARKEQELTKKLQTRER 505
Query: 706 RLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTL 765
++ A EK + + E + E+ ++ L +AI E + + +A+T
Sbjct: 506 EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 565
Query: 766 HKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAER 803
EL S +EK +Q+ +N LEAE+
Sbjct: 566 RTRILELESSLEKSLQE-----NKNQSKDLAVHLEAEK 598
Score = 45.1 bits (105), Expect = 3e-04
Identities = 79/497 (15%), Positives = 210/497 (42%), Gaps = 54/497 (10%)
Query: 363 LTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDG--------- 413
L E + E+L +RL EL+ + + ++ K T ++ E++E
Sbjct: 311 LLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETK 370
Query: 414 --TEETLSQHSDGIVEYGPK---KSRPGLSMR---RKPPYRSHSLSPSPVNKHKQFHLER 465
ETL + I + + + G +R K + ++ ++ R
Sbjct: 371 RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEAR 430
Query: 466 KRQRKPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKG 525
++ + + ++ + + E + +V++ + + EE+ K+ +
Sbjct: 431 RKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELA 490
Query: 526 TPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEH-------SLLPLMLEQFPFLYV 578
E K+ +R+ Q + +++ +K+S+ +L L L++ L
Sbjct: 491 RKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTE 550
Query: 579 SGPTL------SKMWKQQIAQVEQLKKEACRENRSKKK-LQDEIEEALRRHDL-LTTLVK 630
S L ++ ++ +I ++E +++ +EN+++ K L +E +H+ +T +V+
Sbjct: 551 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVE 610
Query: 631 KEYEHNKRLQDFKDCIRRQRL---------TQSKIKENRQQIVRARKYYDDYRVQLCAKM 681
K + L+ +D + ++L K++E +Q + Q +
Sbjct: 611 KHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEE 670
Query: 682 MRMRTREEMIFKKLFEEGLNIQ-------KQRLRDLRNYAKEKRDEQRRRHQDELDSMEN 734
M +T E++ K+ E L+ + + +L + + K++ D+ ++ + ++D +N
Sbjct: 671 MNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKN 730
Query: 735 YYKDQFSLLAEAISQEHQ-ELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDD 793
+++ Q ++I +EH+ ++ EK+ +++++ L+ + +K +++ Q + + D
Sbjct: 731 HHQQQ----VDSIIKEHEVSIQRTEKALKDQINQLELLLKER-DKHLKEHQAHVENLEAD 785
Query: 794 VFFRELEAERFRSRLQL 810
+ E E ++ ++L +
Sbjct: 786 IKRSEGELQQASAKLDV 802
Score = 43.5 bits (101), Expect = 8e-04
Identities = 40/212 (18%), Positives = 100/212 (47%), Gaps = 14/212 (6%)
Query: 589 QQIAQVEQLKKEACRE-NRSKKKLQDEIEEALRRHDLLTTLVKKEYE-HNKRLQDFKDCI 646
+Q+A+VE KK+ C E + K ++QD +++ +++ + VK + + +L+D
Sbjct: 840 KQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN--- 896
Query: 647 RRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQR 706
+ Q T+ + E I++ R+ +++ + + + I + +E Q+++
Sbjct: 897 KEQEQTKQILVEKENMILQMREGQKK-EIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 955
Query: 707 LRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQT-- 764
+ ++ AKE ++ +++ D+ E K + A +SQ+ ++ A+ AQ
Sbjct: 956 MEKVKQKAKEMQETLKKKLLDQ----EAKLKKELENTALELSQKEKQFNAKMLEMAQANS 1011
Query: 765 --LHKVKRELRSKMEKEIQQLQDMITQNDDDV 794
+ L + +++I+ L ++ + +DV
Sbjct: 1012 AGISDAVSRLETNQKEQIESLTEVHRRELNDV 1043
Score = 40.4 bits (93), Expect = 0.007
Identities = 82/488 (16%), Positives = 196/488 (40%), Gaps = 79/488 (16%)
Query: 366 QELHDVSEKLSQRLSELDWMLKSALGDRIKEKTD-----HKEENTGNEEVEDGTE----- 415
++L +E R+ EL+ L+ +L + + D E+N N+E+ E
Sbjct: 556 RDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTE 615
Query: 416 -ETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHK----QFHLERKRQRK 470
E+L D + + + + + K K Q H+E ++
Sbjct: 616 LESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKT 675
Query: 471 PRETDVRQFQAQAFTEAFERELR-RHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPEC 529
+ DV+Q + ++ + L+ RHK++E + L+ ++T+K+ + + +
Sbjct: 676 LEKLDVKQTELESLSSELSEVLKARHKLEEELSVLK-----DQTDKMKQELEAKMDEQKN 730
Query: 530 SQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQ 589
++ S + + + KA+ ++++ L L+L++ K K+
Sbjct: 731 HHQQQVDS---IIKEHEVSIQRTEKALKDQINQ---LELLLKE----------RDKHLKE 774
Query: 590 QIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQ 649
A VE L+ + K+ + E+++A + D+ + +E K ++ ++++
Sbjct: 775 HQAHVENLEADI-------KRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQK 827
Query: 650 RL---TQSKIKENRQQIVRARKY-----YDDYRVQLCAKMMRMRTREE----------MI 691
L T+ + + V A+K D +++Q+ M ++ + +
Sbjct: 828 LLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQV 887
Query: 692 FKKLFEEGLNIQ---KQRLRDLRNYAKEKRDEQRRR----------HQDELDSMENYYKD 738
++ E+G Q KQ L + N + R+ Q++ +D + + Y+
Sbjct: 888 YESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET 947
Query: 739 QFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRE 798
+F + ++ +++K + K +TL K + +K++KE++ ++Q + +
Sbjct: 948 KF----KNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKM 1003
Query: 799 LEAERFRS 806
LE + S
Sbjct: 1004 LEMAQANS 1011
Score = 39.3 bits (90), Expect = 0.015
Identities = 42/218 (19%), Positives = 96/218 (44%), Gaps = 13/218 (5%)
Query: 583 LSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNK-RLQD 641
LS+ + + ++ +L++E + ++KK LQ+E + +L D ++++ + K RL++
Sbjct: 178 LSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRN 237
Query: 642 -------FKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKK 694
K + + + KE + D V+ + + R+E + K+
Sbjct: 238 GPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKR 297
Query: 695 LFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQEL 754
+E + K++ L KE EQ EL+ +++ + + + L + +
Sbjct: 298 C-KETIQSHKEQC-TLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLI 355
Query: 755 KAREKSQAQTLHKVKRELRSKM---EKEIQQLQDMITQ 789
+ E+ + + + KR++ + E+EI QL+ I Q
Sbjct: 356 EQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 393
Score = 33.9 bits (76), Expect = 0.63
Identities = 49/264 (18%), Positives = 122/264 (46%), Gaps = 48/264 (18%)
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIR 647
K+ Q+E KEA ++ L++E+++ +R D L K E E +K + +
Sbjct: 1461 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCL----KGEMEDDKSKME-----K 1511
Query: 648 RQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQ-KQR 706
++ ++++K +I+ + + K + + + E++ K + + +I+ K+
Sbjct: 1512 KESNLETELKSQTARIMELEDH-------ITQKTIEIESLNEVL--KNYNQQKDIEHKEL 1562
Query: 707 LRDLRNYAK--EKRDEQRRRHQDELDSMENYY----------KDQFSLLAEAISQEHQEL 754
++ L+++ + E++D + + ++++ ++EN K + + ++ + +EL
Sbjct: 1563 VQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1622
Query: 755 KARE---------------KSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFREL 799
KA E + Q + +K++L S+ME++ +Q + + ++ +
Sbjct: 1623 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQ 1682
Query: 800 EAERFRSRLQ--LASFQYSKSPSL 821
E ER L+ L S + S+S +L
Sbjct: 1683 EREREVHILEEKLKSVESSQSETL 1706
>gi|27436948 lamin A/C isoform 3 [Homo sapiens]
Length = 634
Score = 50.1 bits (118), Expect = 8e-06
Identities = 52/233 (22%), Positives = 104/233 (44%), Gaps = 25/233 (10%)
Query: 594 VEQLKKEACRENRSKKKLQDEIEEALRRH-----DLLTTLVK-KEYEH--NKRLQDFKDC 645
++ + KE R K+++E +E R+ DL+ + K+ E N +
Sbjct: 92 LDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTA 151
Query: 646 IRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQ 705
+ +R + ++ + R Q+ + + + QL ++EM+ + E L K+
Sbjct: 152 LSEKRTLEGELHDLRGQVAKLEAALGEAKKQL---------QDEMLRRVDAENRLQTMKE 202
Query: 706 RLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQF-SLLAEAISQEHQELKAREKSQAQT 764
L +N E+ E +RRH+ L ++N + +F S LA+A+ QEL+A+ + Q +
Sbjct: 203 ELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL----QELRAQHEDQVE- 257
Query: 765 LHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSK 817
+ K+EL ++ + +N + V E ++ R R+ S Q S+
Sbjct: 258 --QYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQ 308
Score = 38.9 bits (89), Expect = 0.020
Identities = 48/244 (19%), Positives = 110/244 (45%), Gaps = 32/244 (13%)
Query: 590 QIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKK-EYEHNKRLQDFKDCIRR 648
Q+A++E EA KK+LQDE+ + + L T+ ++ +++ N ++ ++ RR
Sbjct: 168 QVAKLEAALGEA------KKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRR 221
Query: 649 QRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLR 708
+I +Q+ ++ +L + +R + E ++ +E +L
Sbjct: 222 HETRLVEIDNGKQR---------EFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLD 272
Query: 709 DLRNYAKEKRD------EQRRRHQDELDSMENYYKDQFSLLA--EAISQEHQELKAREKS 760
+ R A+ + E+ ++ + +DS+ LA EA ++ ++ ARE+
Sbjct: 273 NARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERD 332
Query: 761 QAQTLHKVKR----ELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYS 816
++ L K E+R++M++++ + Q+++ D ++E +R L+ +
Sbjct: 333 TSRRLLAEKEREMAEMRARMQQQLDEYQELL----DIKLALDMEIHAYRKLLEGEEERLR 388
Query: 817 KSPS 820
SPS
Sbjct: 389 LSPS 392
>gi|5031875 lamin A/C isoform 2 [Homo sapiens]
Length = 572
Score = 50.1 bits (118), Expect = 8e-06
Identities = 52/233 (22%), Positives = 104/233 (44%), Gaps = 25/233 (10%)
Query: 594 VEQLKKEACRENRSKKKLQDEIEEALRRH-----DLLTTLVK-KEYEH--NKRLQDFKDC 645
++ + KE R K+++E +E R+ DL+ + K+ E N +
Sbjct: 92 LDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTA 151
Query: 646 IRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQ 705
+ +R + ++ + R Q+ + + + QL ++EM+ + E L K+
Sbjct: 152 LSEKRTLEGELHDLRGQVAKLEAALGEAKKQL---------QDEMLRRVDAENRLQTMKE 202
Query: 706 RLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQF-SLLAEAISQEHQELKAREKSQAQT 764
L +N E+ E +RRH+ L ++N + +F S LA+A+ QEL+A+ + Q +
Sbjct: 203 ELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL----QELRAQHEDQVE- 257
Query: 765 LHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSK 817
+ K+EL ++ + +N + V E ++ R R+ S Q S+
Sbjct: 258 --QYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQ 308
Score = 38.9 bits (89), Expect = 0.020
Identities = 48/244 (19%), Positives = 110/244 (45%), Gaps = 32/244 (13%)
Query: 590 QIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKK-EYEHNKRLQDFKDCIRR 648
Q+A++E EA KK+LQDE+ + + L T+ ++ +++ N ++ ++ RR
Sbjct: 168 QVAKLEAALGEA------KKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRR 221
Query: 649 QRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLR 708
+I +Q+ ++ +L + +R + E ++ +E +L
Sbjct: 222 HETRLVEIDNGKQR---------EFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLD 272
Query: 709 DLRNYAKEKRD------EQRRRHQDELDSMENYYKDQFSLLA--EAISQEHQELKAREKS 760
+ R A+ + E+ ++ + +DS+ LA EA ++ ++ ARE+
Sbjct: 273 NARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERD 332
Query: 761 QAQTLHKVKR----ELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYS 816
++ L K E+R++M++++ + Q+++ D ++E +R L+ +
Sbjct: 333 TSRRLLAEKEREMAEMRARMQQQLDEYQELL----DIKLALDMEIHAYRKLLEGEEERLR 388
Query: 817 KSPS 820
SPS
Sbjct: 389 LSPS 392
>gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens]
Length = 664
Score = 50.1 bits (118), Expect = 8e-06
Identities = 52/233 (22%), Positives = 104/233 (44%), Gaps = 25/233 (10%)
Query: 594 VEQLKKEACRENRSKKKLQDEIEEALRRH-----DLLTTLVK-KEYEH--NKRLQDFKDC 645
++ + KE R K+++E +E R+ DL+ + K+ E N +
Sbjct: 92 LDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTA 151
Query: 646 IRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQ 705
+ +R + ++ + R Q+ + + + QL ++EM+ + E L K+
Sbjct: 152 LSEKRTLEGELHDLRGQVAKLEAALGEAKKQL---------QDEMLRRVDAENRLQTMKE 202
Query: 706 RLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQF-SLLAEAISQEHQELKAREKSQAQT 764
L +N E+ E +RRH+ L ++N + +F S LA+A+ QEL+A+ + Q +
Sbjct: 203 ELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL----QELRAQHEDQVE- 257
Query: 765 LHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSK 817
+ K+EL ++ + +N + V E ++ R R+ S Q S+
Sbjct: 258 --QYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQ 308
Score = 38.9 bits (89), Expect = 0.020
Identities = 48/244 (19%), Positives = 110/244 (45%), Gaps = 32/244 (13%)
Query: 590 QIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKK-EYEHNKRLQDFKDCIRR 648
Q+A++E EA KK+LQDE+ + + L T+ ++ +++ N ++ ++ RR
Sbjct: 168 QVAKLEAALGEA------KKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRR 221
Query: 649 QRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLR 708
+I +Q+ ++ +L + +R + E ++ +E +L
Sbjct: 222 HETRLVEIDNGKQR---------EFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLD 272
Query: 709 DLRNYAKEKRD------EQRRRHQDELDSMENYYKDQFSLLA--EAISQEHQELKAREKS 760
+ R A+ + E+ ++ + +DS+ LA EA ++ ++ ARE+
Sbjct: 273 NARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERD 332
Query: 761 QAQTLHKVKR----ELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYS 816
++ L K E+R++M++++ + Q+++ D ++E +R L+ +
Sbjct: 333 TSRRLLAEKEREMAEMRARMQQQLDEYQELL----DIKLALDMEIHAYRKLLEGEEERLR 388
Query: 817 KSPS 820
SPS
Sbjct: 389 LSPS 392
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 49.7 bits (117), Expect = 1e-05
Identities = 77/374 (20%), Positives = 164/374 (43%), Gaps = 64/374 (17%)
Query: 470 KPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPEC 529
K + D + +++ E ERE R + + + E+E E +K+ E R +
Sbjct: 551 KASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDK 610
Query: 530 SQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSL--LPLMLEQFPFLYVSGPTLSKMW 587
+ RK + ++ + +K ++ S + L+L+ +Y S P
Sbjct: 611 EKGKHDDGRKKEAEIIK------QLKIELKKAQESQKEMKLLLD----MYRSAP------ 654
Query: 588 KQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIR 647
K+Q +V+ + E KK + E+E+ +R L L KE + NK++ D +D +R
Sbjct: 655 KEQRDKVQLMAAE--------KKSKAELEDLRQR---LKDLEDKEKKENKKMAD-EDALR 702
Query: 648 RQRLTQSKIKENRQQIVRAR--------------KYYDDYRVQLCAKMMRMRTREEMIFK 693
+ R + +I+ ++++ A+ + ++D + Q M ++R +++ FK
Sbjct: 703 KIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFK 762
Query: 694 KLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDS---MENYYKDQFSLLAEAISQE 750
+ E I+ ++ L KE+ +Q + ++D+ + +++ LL I
Sbjct: 763 LMSE---RIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTG 819
Query: 751 HQELKAR------EKSQAQTLHKVKRELRSKME---KEIQQLQDMITQN----DDDVF-F 796
+EL R K +A ++ +L++++E K++ QD I +N + D+F F
Sbjct: 820 EKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDMFNF 879
Query: 797 RELEAERFRSRLQL 810
+ + + R R +L
Sbjct: 880 KRAQEDISRLRRKL 893
Score = 32.0 bits (71), Expect = 2.4
Identities = 46/207 (22%), Positives = 94/207 (45%), Gaps = 28/207 (13%)
Query: 593 QVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLT 652
QVE ++++ E KKL+ E+ ++ D L V+KEYE + +F+ +
Sbjct: 419 QVELIERD---EVSLHKKLRTEV---IQLEDTLAQ-VRKEYEMLRI--EFEQTLAANEQA 469
Query: 653 QSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRD--- 709
+E R I + ++ QL +++R + +KL E ++ K RLR
Sbjct: 470 GPINREMRHLISSLQ----NHNHQLKGEVLRYK-------RKLREAQSDLNKTRLRSGSA 518
Query: 710 ---LRNYAKEKRDE--QRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQT 764
++ ++ +DE + + ++L S + K E S+ +E + RE+ + +
Sbjct: 519 LLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKER 578
Query: 765 LHKVKRELRSKMEKEIQQLQDMITQND 791
+ +RE + E+E Q+L++ + D
Sbjct: 579 EREREREKEKEREREKQKLKESEKERD 605
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,961,822
Number of Sequences: 37866
Number of extensions: 1650333
Number of successful extensions: 9414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 692
Number of HSP's that attempted gapping in prelim test: 7286
Number of HSP's gapped (non-prelim): 2364
length of query: 821
length of database: 18,247,518
effective HSP length: 111
effective length of query: 710
effective length of database: 14,044,392
effective search space: 9971518320
effective search space used: 9971518320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.