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Search of human proteins with 19923891
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923891 kinesin-like 8 isoform c [Homo sapiens]
(315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923891 kinesin-like 8 isoform c [Homo sapiens] 629 e-180
gi|41871960 kinesin-like 8 isoform b [Homo sapiens] 577 e-165
gi|41871955 kinesin-like 8 isoform a [Homo sapiens] 577 e-165
gi|41871946 kinesin-like 8 isoform a [Homo sapiens] 577 e-165
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 400 e-112
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 400 e-112
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 400 e-112
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens] 375 e-104
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens] 375 e-104
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens] 375 e-104
gi|91825557 kinesin light chain 3 [Homo sapiens] 337 1e-92
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens] 211 7e-55
gi|34304360 nephrocystin 3 [Homo sapiens] 67 3e-11
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 45 6e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 44 2e-04
gi|238908495 similar to pleckstrin homology domain protein (5V32... 44 2e-04
gi|81295809 pericentrin [Homo sapiens] 43 3e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 42 7e-04
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 42 7e-04
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 42 7e-04
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 42 7e-04
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 42 7e-04
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 42 7e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 42 0.001
gi|55770834 centromere protein F [Homo sapiens] 41 0.001
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 41 0.002
gi|28416946 myosin 18A isoform a [Homo sapiens] 41 0.002
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 41 0.002
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 41 0.002
gi|31542661 transmembrane protein 57 [Homo sapiens] 40 0.002
>gi|19923891 kinesin-like 8 isoform c [Homo sapiens]
Length = 315
Score = 629 bits (1622), Expect = e-180
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE
Sbjct: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
Query: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR
Sbjct: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
Query: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP
Sbjct: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
Query: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED
Sbjct: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
Query: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVSIPCPP 300
LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVSIPCPP
Sbjct: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVSIPCPP 300
Query: 301 HPTPRTPHHCCFGLS 315
HPTPRTPHHCCFGLS
Sbjct: 301 HPTPRTPHHCCFGLS 315
>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
Length = 637
Score = 577 bits (1487), Expect = e-165
Identities = 294/295 (99%), Positives = 295/295 (100%)
Query: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE
Sbjct: 19 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 78
Query: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR
Sbjct: 79 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 138
Query: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP
Sbjct: 139 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 198
Query: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED
Sbjct: 199 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 258
Query: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAV+
Sbjct: 259 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVA 313
Score = 82.0 bits (201), Expect = 6e-16
Identities = 42/92 (45%), Positives = 58/92 (63%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLC++ALE E+ G HPDVA LN LAL+
Sbjct: 306 GPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLC 365
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q KY+ AL+I E LGPD+P V+
Sbjct: 366 QNQGKYEAVERYYQRALAIYEGQLGPDNPNVA 397
>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 577 bits (1487), Expect = e-165
Identities = 294/295 (99%), Positives = 295/295 (100%)
Query: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE
Sbjct: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
Query: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR
Sbjct: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
Query: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP
Sbjct: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
Query: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED
Sbjct: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
Query: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAV+
Sbjct: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVA 295
Score = 82.0 bits (201), Expect = 6e-16
Identities = 42/92 (45%), Positives = 58/92 (63%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLC++ALE E+ G HPDVA LN LAL+
Sbjct: 288 GPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLC 347
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q KY+ AL+I E LGPD+P V+
Sbjct: 348 QNQGKYEAVERYYQRALAIYEGQLGPDNPNVA 379
>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 577 bits (1487), Expect = e-165
Identities = 294/295 (99%), Positives = 295/295 (100%)
Query: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE
Sbjct: 1 MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE 60
Query: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR
Sbjct: 61 EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR 120
Query: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP
Sbjct: 121 DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP 180
Query: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED
Sbjct: 181 NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED 240
Query: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAV+
Sbjct: 241 LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVA 295
Score = 82.0 bits (201), Expect = 6e-16
Identities = 42/92 (45%), Positives = 58/92 (63%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLC++ALE E+ G HPDVA LN LAL+
Sbjct: 288 GPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLC 347
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q KY+ AL+I E LGPD+P V+
Sbjct: 348 QNQGKYEAVERYYQRALAIYEGQLGPDNPNVA 379
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 400 bits (1029), Expect = e-112
Identities = 201/282 (71%), Positives = 245/282 (86%), Gaps = 4/282 (1%)
Query: 16 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 75
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
Query: 76 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 135
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
Query: 136 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 193
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN +E+DP G+ +
Sbjct: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPN-DEDDPGQGIQQQH 195
Query: 194 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 253
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
Query: 254 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAV+
Sbjct: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVA 297
Score = 85.9 bits (211), Expect = 4e-17
Identities = 43/92 (46%), Positives = 60/92 (65%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLCK+ALE E+ G+ HPDVA LN LAL+
Sbjct: 290 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLC 349
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q KY+E + AL I ++ LGPD P V+
Sbjct: 350 QNQGKYEEVEYYYQRALEIYQTKLGPDDPNVA 381
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 400 bits (1029), Expect = e-112
Identities = 201/282 (71%), Positives = 245/282 (86%), Gaps = 4/282 (1%)
Query: 16 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 75
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
Query: 76 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 135
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
Query: 136 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 193
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN +E+DP G+ +
Sbjct: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPN-DEDDPGQGIQQQH 195
Query: 194 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 253
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
Query: 254 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAV+
Sbjct: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVA 297
Score = 85.9 bits (211), Expect = 4e-17
Identities = 43/92 (46%), Positives = 60/92 (65%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLCK+ALE E+ G+ HPDVA LN LAL+
Sbjct: 290 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLC 349
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q KY+E + AL I ++ LGPD P V+
Sbjct: 350 QNQGKYEEVEYYYQRALEIYQTKLGPDDPNVA 381
>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
Length = 560
Score = 400 bits (1029), Expect = e-112
Identities = 201/282 (71%), Positives = 245/282 (86%), Gaps = 4/282 (1%)
Query: 16 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 75
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
Query: 76 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 135
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
Query: 136 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 193
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN +E+DP G+ +
Sbjct: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPN-DEDDPGQGIQQQH 195
Query: 194 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 253
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
Query: 254 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAV+
Sbjct: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVA 297
Score = 85.9 bits (211), Expect = 4e-17
Identities = 43/92 (46%), Positives = 60/92 (65%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLCK+ALE E+ G+ HPDVA LN LAL+
Sbjct: 290 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLC 349
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q KY+E + AL I ++ LGPD P V+
Sbjct: 350 QNQGKYEEVEYYYQRALEIYQTKLGPDDPNVA 381
>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 375 bits (962), Expect = e-104
Identities = 200/284 (70%), Positives = 227/284 (79%), Gaps = 8/284 (2%)
Query: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
Query: 72 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 131
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
Query: 132 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 191
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
Query: 192 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 251
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
Query: 252 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAV+
Sbjct: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVA 282
Score = 78.6 bits (192), Expect = 7e-15
Identities = 41/92 (44%), Positives = 58/92 (63%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLCK+ALE E+ G+ HPDVA L+ LAL+
Sbjct: 275 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLC 334
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q K +E + AL I + LGPD P V+
Sbjct: 335 QNQGKAEEVEYYYRRALEIYATRLGPDDPNVA 366
>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 375 bits (962), Expect = e-104
Identities = 200/284 (70%), Positives = 227/284 (79%), Gaps = 8/284 (2%)
Query: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
Query: 72 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 131
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
Query: 132 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 191
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
Query: 192 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 251
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
Query: 252 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAV+
Sbjct: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVA 282
Score = 78.6 bits (192), Expect = 7e-15
Identities = 41/92 (44%), Positives = 58/92 (63%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLCK+ALE E+ G+ HPDVA L+ LAL+
Sbjct: 275 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLC 334
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q K +E + AL I + LGPD P V+
Sbjct: 335 QNQGKAEEVEYYYRRALEIYATRLGPDDPNVA 366
>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 375 bits (962), Expect = e-104
Identities = 200/284 (70%), Positives = 227/284 (79%), Gaps = 8/284 (2%)
Query: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
Query: 72 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 131
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
Query: 132 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 191
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
Query: 192 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 251
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
Query: 252 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAV+
Sbjct: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVA 282
Score = 78.6 bits (192), Expect = 7e-15
Identities = 41/92 (44%), Positives = 58/92 (63%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + PA TL+NL + Y +G+Y+ A PLCK+ALE E+ G+ HPDVA L+ LAL+
Sbjct: 275 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLC 334
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++Q K +E + AL I + LGPD P V+
Sbjct: 335 QNQGKAEEVEYYYRRALEIYATRLGPDDPNVA 366
>gi|91825557 kinesin light chain 3 [Homo sapiens]
Length = 504
Score = 337 bits (863), Expect = 1e-92
Identities = 183/282 (64%), Positives = 215/282 (76%), Gaps = 9/282 (3%)
Query: 16 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGL--VHEKARQLRR 73
RLS EE++ TR V QGLEALR+EH + L+ E L G GL + EK + +
Sbjct: 17 RLSPEELVRQTRQVVQGLEALRAEHHGLAGHLA---EALAGQGPAAGLEMLEEKQQVVSH 73
Query: 74 SMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRS 133
S+E IELGL EAQV+LAL++H+ +E+EKQ+LR+Q RRL QEN WLR+EL TQ+RL+ S
Sbjct: 74 SLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRAS 133
Query: 134 EQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR 193
E++VAQLEEEK+HLEFLGQLRQYD S++ E +DSL LFP+EEEE
Sbjct: 134 EESVAQLEEEKRHLEFLGQLRQYDPPAE-SQQSESPPRRDSLASLFPSEEEERKG---PE 189
Query: 194 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 253
GA AAQQGGYEIPARLRTLHNLVIQYA QGRYEVAVPLC+QALEDLER+SG HPDVA
Sbjct: 190 AAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVA 249
Query: 254 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
TMLNILALVYRDQNKYKEA LL+DAL IRE TLGP+HPAV+
Sbjct: 250 TMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVA 291
>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
Length = 545
Score = 211 bits (537), Expect = 7e-55
Identities = 104/133 (78%), Positives = 117/133 (87%), Gaps = 2/133 (1%)
Query: 163 SEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYA 222
++E++GD KD+LDDLFPNE+E+ P+ S G G + Q GGYEIPARLRTLHNLVIQYA
Sbjct: 75 AQEEKGDVPKDTLDDLFPNEDEQSPAP--SPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 132
Query: 223 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI 282
+QGRYEVAVPLCKQALEDLE+TSG HPDVATMLNILALVYRDQNKYKEAAHLLNDAL+I
Sbjct: 133 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 192
Query: 283 RESTLGPDHPAVS 295
RE TLG DHPAV+
Sbjct: 193 REKTLGKDHPAVA 205
Score = 106 bits (264), Expect = 3e-23
Identities = 92/294 (31%), Positives = 138/294 (46%), Gaps = 21/294 (7%)
Query: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
Query: 72 RRSMENIELGLSEAQ-----VMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGT 126
RRS+E IELGL EAQ V L E E+ + + + G
Sbjct: 62 RRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSP------GGGDVSGQHGGY 115
Query: 127 Q--QRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDL---FPN 181
+ RL+ V Q + ++ + +Q ED + + L+ L + +
Sbjct: 116 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
Query: 182 EEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDL 241
+ + + L A + G + PA TL+NL + Y +G+Y+ A PLCK+ALE
Sbjct: 176 QNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIR 235
Query: 242 ERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
E+ G+ HPDVA L+ LAL+ ++Q K +E + AL I + LGPD P V+
Sbjct: 236 EKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVA 289
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 66.6 bits (161), Expect = 3e-11
Identities = 36/92 (39%), Positives = 49/92 (53%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + P RTL+ L + Y Q E A K++LE ER G HPD A LN LA +
Sbjct: 1086 GKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALC 1145
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
++ +Y +A L AL IR L PDHP+++
Sbjct: 1146 NEKKQYDKAEELYERALDIRRRALAPDHPSLA 1177
Score = 60.5 bits (145), Expect = 2e-09
Identities = 35/87 (40%), Positives = 49/87 (56%)
Query: 208 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQN 267
P+ T+ +L I Y G+ + AVPL + A+E +++ G HP VAT L LA++Y
Sbjct: 1174 PSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMK 1233
Query: 268 KYKEAAHLLNDALSIRESTLGPDHPAV 294
K+ EA L AL I E +LG HP V
Sbjct: 1234 KHVEALPLYERALKIYEDSLGRMHPRV 1260
Score = 50.8 bits (120), Expect = 2e-06
Identities = 28/80 (35%), Positives = 39/80 (48%)
Query: 208 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQN 267
P ++LH L Y ++ A L KQALE E G HP A L LA +Y+ QN
Sbjct: 982 PRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHPYTARELEALATLYQKQN 1041
Query: 268 KYKEAAHLLNDALSIRESTL 287
KY++A H + I + +
Sbjct: 1042 KYEQAEHFRKKSFKIHQKAI 1061
Score = 50.1 bits (118), Expect = 3e-06
Identities = 28/92 (30%), Positives = 49/92 (53%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + P ++L+NL + +Y+ A L ++AL+ R HP +A + LA++Y
Sbjct: 1128 GPDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILY 1187
Query: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
+ K +A L A+ IR+ + GP HP+V+
Sbjct: 1188 KKMGKLDKAVPLYELAVEIRQKSFGPKHPSVA 1219
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/113 (31%), Positives = 47/113 (41%), Gaps = 24/113 (21%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVA------------------------VPLCKQALE 239
G + P R L L Y Q +YE A L ++AL+
Sbjct: 1020 GADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQ 1079
Query: 240 DLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHP 292
E T G+ PD A LN L ++Y QN + A L +L +RE LGPDHP
Sbjct: 1080 LEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHP 1132
Score = 45.4 bits (106), Expect = 6e-05
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 3/93 (3%)
Query: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
G + P+ L NL + Y+ ++ A+PL ++AL+ E + GR HP V L LA++
Sbjct: 1212 GPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLS 1271
Query: 264 RDQNKYKEAAHLLNDALSIRE---STLGPDHPA 293
+ +++AA L A+ I+E S LG P+
Sbjct: 1272 YEGGDFEKAAELYKRAMEIKEAETSLLGGKAPS 1304
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 228 EVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTL 287
+ VPL +++LE E HP VA L+ LA VY K+ A L AL I E+
Sbjct: 961 QAIVPL-QRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAY 1019
Query: 288 GPDHP 292
G DHP
Sbjct: 1020 GADHP 1024
Score = 28.9 bits (63), Expect = 6.2
Identities = 15/44 (34%), Positives = 22/44 (50%)
Query: 252 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
+A + L +D +A L +L IRE+ L PDHP V+
Sbjct: 942 LADLYETLGRFLKDLGLLSQAIVPLQRSLEIRETALDPDHPRVA 985
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 45.4 bits (106), Expect = 6e-05
Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 30/170 (17%)
Query: 8 QRDEPAGHRLSQEEILGSTRLVS-------------QGLEA----LRSEHQAVLQSLSQT 50
Q G RLS+EE+L +T ++ + LEA ++ E + V+Q
Sbjct: 1704 QEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNA 1763
Query: 51 IECLQQGGHEEGLVHEKARQ-------LRRSMENIELGLSEAQVMLALASHLSTVESEK- 102
E ++ E + E+ ++ L R+ EN+E +++ Q LA A ++ + S K
Sbjct: 1764 EEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQ 1823
Query: 103 -QKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQL----EEEKKHL 147
QKL ++VR L E + A Q+ +R E+ + +L EE+KK+L
Sbjct: 1824 IQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL 1873
Score = 30.8 bits (68), Expect = 1.6
Identities = 38/156 (24%), Positives = 68/156 (43%), Gaps = 15/156 (9%)
Query: 34 EALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALAS 93
E L+++ ++ Q + I LQ V E+ L +S +E + E L+
Sbjct: 883 EELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKE------LSE 936
Query: 94 HLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHL----EF 149
+ E +L A+ R+L E L+ E+ + L +SE+ E + K+L EF
Sbjct: 937 RVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEF 996
Query: 150 LGQ-LRQYDEDGHTSEEKEGDATKDSLDDLFPNEEE 184
L + + + + +E A + +LDDL EE+
Sbjct: 997 LNEDISKLNRAAKVVQE----AHQQTLDDLHMEEEK 1028
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/163 (22%), Positives = 77/163 (47%), Gaps = 9/163 (5%)
Query: 34 EALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALAS 93
E +R + + +L+ QT E +Q G +E + E+ Q+R E + + + M
Sbjct: 269 EQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMR---EQEEQMREQEE 324
Query: 94 HLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQ-RLQRSEQAVAQLEEEKKHLEFLGQ 152
+ E + + + Q+ +E W ++E G Q+ ++Q+ E+ V + EE+ + E Q
Sbjct: 325 QMGKQEEQMWEQKEQMWEQ-KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE--EQ 381
Query: 153 LRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQ 195
+R+ +E EE+ G+ K+ + + E++ G + Q
Sbjct: 382 MRKQEEQMRKQEEQMGE-QKEQMGEQKEQMREQEEQMGEQKEQ 423
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 34 EALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENI-----ELGLSEAQVM 88
E +R + + + + Q E +Q G +E + E+ Q+ E + ++G E Q M
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ-M 361
Query: 89 LALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLE 148
+ E + +K Q+R+ QE Q + E +Q+ Q EQ E+E++ E
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRK--QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGE 419
Query: 149 FLGQLRQYDEDGHTSEEKE 167
Q+R+ +E H E+KE
Sbjct: 420 QKEQMRKQEE--HMGEQKE 436
Score = 38.1 bits (87), Expect = 0.010
Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 26/162 (16%)
Query: 7 GQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHE 66
GQ E G QEE +G E ++ + + + + Q + +Q G +E V +
Sbjct: 192 GQMGEQEGQMGEQEEQMGEQE------EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 67 KARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGT 126
+ Q+++ E + +++++R Q ++ ++ + + + T
Sbjct: 246 QEEQVQKQEEQMR--------------------KQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 127 QQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEG 168
+Q Q EQ E+E++ E Q+R+ +E EE+ G
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG 327
Score = 36.6 bits (83), Expect = 0.030
Identities = 40/180 (22%), Positives = 78/180 (43%), Gaps = 6/180 (3%)
Query: 7 GQRDEPAGHRLSQE-EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVH 65
GQ E G QE ++ V + +R + V + Q E Q +EG V
Sbjct: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
Query: 66 EKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAG 125
E+ Q+R + ++G E Q M + E + QK Q+ ++ + +++
Sbjct: 182 EQEGQVRE--QEGQMGEQEGQ-MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
Query: 126 TQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEE 185
++++Q+ E+ V + EE+ + E Q+R+ +E EE+ + + + E+EE
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQE--EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEE 296
>gi|238908495 similar to pleckstrin homology domain protein (5V327)
[Homo sapiens]
Length = 506
Score = 43.5 bits (101), Expect = 2e-04
Identities = 30/144 (20%), Positives = 71/144 (49%), Gaps = 7/144 (4%)
Query: 33 LEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLAL- 91
++ LR E + + + L T CL+ E+ + L++++E + + + ML
Sbjct: 205 VQELRMEQEQIKRELELTARCLKGVEQEKKELRHLTESLQQTLEELSIEKKKTLEMLEEN 264
Query: 92 ASHLSTVESEKQK------LRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKK 145
+HL T+ ++ ++ L + +R++ ++ Q L +E ++R++ +E+ LEEE++
Sbjct: 265 ENHLQTLANQSEQPPPSGGLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEERE 324
Query: 146 HLEFLGQLRQYDEDGHTSEEKEGD 169
Q Q T+E+++ +
Sbjct: 325 FYSSQSQALQNSLQELTAEKQQAE 348
Score = 38.1 bits (87), Expect = 0.010
Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 24/207 (11%)
Query: 1 MSGLVLGQRDEPA---GHRLSQEEILGSTRLVS-------QGLEALRSEHQAVLQSLSQT 50
+ G ++ ++EP+ ++S ++ G+ L + Q LE L+ + ++ +Q
Sbjct: 86 LGGCLVEPKEEPSMPYAMKISHQDFHGNILLAAESEFEQTQWLEMLQESGKVTWKN-AQL 144
Query: 51 IECLQQGGHEEGL--VHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQ 108
E + + +GL EK L + ME E + + L +E+EKQ+
Sbjct: 145 GEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREELERLNQVLEAEKQQFEEV 204
Query: 109 VRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEG 168
V+ L E + ++ EL T + L+ EQ EKK L L + Q + + E+K+
Sbjct: 205 VQELRMEQEQIKRELELTARCLKGVEQ-------EKKELRHLTESLQQTLEELSIEKKKT 257
Query: 169 ----DATKDSLDDLFPNEEEEDPSNGL 191
+ ++ L L E+ PS GL
Sbjct: 258 LEMLEENENHLQTLANQSEQPPPSGGL 284
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/162 (25%), Positives = 71/162 (43%), Gaps = 24/162 (14%)
Query: 28 LVSQGLEALRSEHQAVLQS------------LSQTIECLQQGGHEEGLVHEKARQLRRSM 75
+++Q LE L+ +H+ LQS L+ T+ QG H+ EK L
Sbjct: 1011 ILTQELEKLKRKHEGELQSVRDHLRTEVSTELAGTVAHELQGVHQGEFGSEKKTALHEKE 1070
Query: 76 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ--RS 133
E + L ++AQ + EK+ L Q+++ + Q L+D++ ++ RS
Sbjct: 1071 ETLRLQSAQAQPFH---------QEEKESLSLQLQKKNHQVQQLKDQVLSLSHEIEECRS 1121
Query: 134 EQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSL 175
E V Q E+++ E L D + S + G A +D+L
Sbjct: 1122 ELEVLQQRRERENREGANLLSMLKADVNLSHSERG-ALQDAL 1162
Score = 38.5 bits (88), Expect = 0.008
Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 34/179 (18%)
Query: 11 EPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQ 70
E A R E+I + L L S HQA ++ L + ++ E G
Sbjct: 383 ELAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQS------EHG-------- 428
Query: 71 LRRSMENIELGL--SEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQ 128
R +E++E SE + L L + ++ E K + + ++RRL W + + A T +
Sbjct: 429 --RCLEDLEFKFKESEKEKQLELENLQASYEDLKAQSQEEIRRL-----WSQLDSARTSR 481
Query: 129 RLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTS---------EEKEGDATKDSLDDL 178
Q + QL +E L QL+Q ++ H S E+K DA K +DL
Sbjct: 482 --QELSELHEQLLARTSRVEDLEQLKQREKTQHESELEQLRIYFEKKLRDAEKTYQEDL 538
Score = 31.2 bits (69), Expect = 1.3
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 17/163 (10%)
Query: 26 TRLVSQGLEALRSEHQAV--LQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLS 83
++L + L L+ E Q+ L+ L ++E Q+ V K Q + EL +
Sbjct: 2667 SQLEEEQLRHLQRESQSAKALEELRASLET-QRAQSSRLCVALKHEQTAKDNLQKELRIE 2725
Query: 84 EAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQA------- 136
++ LA S + ++ L A+ R + ++ LR E T+Q QR+++A
Sbjct: 2726 HSRCEALLAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQ 2785
Query: 137 -----VAQLEEEKKH-LEFLGQLRQYDEDG-HTSEEKEGDATK 172
+ +L+EEK ++ L + + H+ ++ E +A K
Sbjct: 2786 AHHALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQK 2828
Score = 28.9 bits (63), Expect = 6.2
Identities = 48/226 (21%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 19 QEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENI 78
+ +L + + L ++Q LQ L + + G ++ QLRR +E +
Sbjct: 2514 RSSLLSEIQALRAQLRMTHLQNQEKLQHLRTALTSAEARGSQQ------EHQLRRQVELL 2567
Query: 79 ELGLSEAQVMLALASHLS-TVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAV 137
+ + + +A L T+ E++K + + L E +RD + + Q+SEQ
Sbjct: 2568 AYKVEQEK---CIAGDLQKTLSEEQEKANSVQKLLAAEQTVVRDLKSDLCESRQKSEQLS 2624
Query: 138 AQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGA 197
L E ++ + L + E+ + +E ++ + L EEE + Q A
Sbjct: 2625 RSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSA 2684
Query: 198 TAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLER 243
A + E+ A L T Q A R VA+ + A ++L++
Sbjct: 2685 KALE----ELRASLET------QRAQSSRLCVALKHEQTAKDNLQK 2720
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/252 (21%), Positives = 114/252 (45%), Gaps = 8/252 (3%)
Query: 21 EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIEL 80
+++ + R ++ +E S + L S + L++ EE A R S E ++
Sbjct: 738 QVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQS 797
Query: 81 GLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQ- 139
L E++V + LAS L EK+K+ ++V ++ E ++ E Q L+ EQ V +
Sbjct: 798 SL-ESEVSV-LASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNEL 855
Query: 140 LEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATA 199
L++ ++ E L ++++Y E EE + + ++ +E + + LS ++
Sbjct: 856 LQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSK 915
Query: 200 AQQGGYE-IPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNI 258
Q E + +++ L N + + Q + ++V + L G+ DV +L
Sbjct: 916 RQSQQLEALQQQVKQLQNQLAECKKQHQEVISV----YRMHLLYAVQGQMDEDVQKVLKQ 971
Query: 259 LALVYRDQNKYK 270
+ + ++Q++ K
Sbjct: 972 ILTMCKNQSQKK 983
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/252 (21%), Positives = 114/252 (45%), Gaps = 8/252 (3%)
Query: 21 EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIEL 80
+++ + R ++ +E S + L S + L++ EE A R S E ++
Sbjct: 727 QVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQS 786
Query: 81 GLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQ- 139
L E++V + LAS L EK+K+ ++V ++ E ++ E Q L+ EQ V +
Sbjct: 787 SL-ESEVSV-LASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNEL 844
Query: 140 LEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATA 199
L++ ++ E L ++++Y E EE + + ++ +E + + LS ++
Sbjct: 845 LQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSK 904
Query: 200 AQQGGYE-IPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNI 258
Q E + +++ L N + + Q + ++V + L G+ DV +L
Sbjct: 905 RQSQQLEALQQQVKQLQNQLAECKKQHQEVISV----YRMHLLYAVQGQMDEDVQKVLKQ 960
Query: 259 LALVYRDQNKYK 270
+ + ++Q++ K
Sbjct: 961 ILTMCKNQSQKK 972
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/252 (21%), Positives = 114/252 (45%), Gaps = 8/252 (3%)
Query: 21 EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIEL 80
+++ + R ++ +E S + L S + L++ EE A R S E ++
Sbjct: 706 QVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQS 765
Query: 81 GLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQ- 139
L E++V + LAS L EK+K+ ++V ++ E ++ E Q L+ EQ V +
Sbjct: 766 SL-ESEVSV-LASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNEL 823
Query: 140 LEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATA 199
L++ ++ E L ++++Y E EE + + ++ +E + + LS ++
Sbjct: 824 LQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSK 883
Query: 200 AQQGGYE-IPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNI 258
Q E + +++ L N + + Q + ++V + L G+ DV +L
Sbjct: 884 RQSQQLEALQQQVKQLQNQLAECKKQHQEVISV----YRMHLLYAVQGQMDEDVQKVLKQ 939
Query: 259 LALVYRDQNKYK 270
+ + ++Q++ K
Sbjct: 940 ILTMCKNQSQKK 951
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/252 (21%), Positives = 114/252 (45%), Gaps = 8/252 (3%)
Query: 21 EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIEL 80
+++ + R ++ +E S + L S + L++ EE A R S E ++
Sbjct: 735 QVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQS 794
Query: 81 GLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQ- 139
L E++V + LAS L EK+K+ ++V ++ E ++ E Q L+ EQ V +
Sbjct: 795 SL-ESEVSV-LASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNEL 852
Query: 140 LEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATA 199
L++ ++ E L ++++Y E EE + + ++ +E + + LS ++
Sbjct: 853 LQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSK 912
Query: 200 AQQGGYE-IPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNI 258
Q E + +++ L N + + Q + ++V + L G+ DV +L
Sbjct: 913 RQSQQLEALQQQVKQLQNQLAECKKQHQEVISV----YRMHLLYAVQGQMDEDVQKVLKQ 968
Query: 259 LALVYRDQNKYK 270
+ + ++Q++ K
Sbjct: 969 ILTMCKNQSQKK 980
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/252 (21%), Positives = 114/252 (45%), Gaps = 8/252 (3%)
Query: 21 EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIEL 80
+++ + R ++ +E S + L S + L++ EE A R S E ++
Sbjct: 735 QVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQS 794
Query: 81 GLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQ- 139
L E++V + LAS L EK+K+ ++V ++ E ++ E Q L+ EQ V +
Sbjct: 795 SL-ESEVSV-LASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNEL 852
Query: 140 LEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATA 199
L++ ++ E L ++++Y E EE + + ++ +E + + LS ++
Sbjct: 853 LQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSK 912
Query: 200 AQQGGYE-IPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNI 258
Q E + +++ L N + + Q + ++V + L G+ DV +L
Sbjct: 913 RQSQQLEALQQQVKQLQNQLAECKKQHQEVISV----YRMHLLYAVQGQMDEDVQKVLKQ 968
Query: 259 LALVYRDQNKYK 270
+ + ++Q++ K
Sbjct: 969 ILTMCKNQSQKK 980
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/252 (21%), Positives = 114/252 (45%), Gaps = 8/252 (3%)
Query: 21 EILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIEL 80
+++ + R ++ +E S + L S + L++ EE A R S E ++
Sbjct: 735 QVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQS 794
Query: 81 GLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQ- 139
L E++V + LAS L EK+K+ ++V ++ E ++ E Q L+ EQ V +
Sbjct: 795 SL-ESEVSV-LASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNEL 852
Query: 140 LEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGATA 199
L++ ++ E L ++++Y E EE + + ++ +E + + LS ++
Sbjct: 853 LQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSK 912
Query: 200 AQQGGYE-IPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNI 258
Q E + +++ L N + + Q + ++V + L G+ DV +L
Sbjct: 913 RQSQQLEALQQQVKQLQNQLAECKKQHQEVISV----YRMHLLYAVQGQMDEDVQKVLKQ 968
Query: 259 LALVYRDQNKYK 270
+ + ++Q++ K
Sbjct: 969 ILTMCKNQSQKK 980
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 6/120 (5%)
Query: 29 VSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVM 88
+ + L A + Q + + L + L + + + E+ + LR + ++EL EA+
Sbjct: 1752 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1811
Query: 89 LALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLE 148
L L V ++Q+ A Q+ L+DE Q+RL ++A+AQLE EK+ +E
Sbjct: 1812 L---QQLREVLRQRQEGEAAALNTVQK---LQDERRLLQERLGSLQRALAQLEAEKREVE 1865
Score = 38.9 bits (89), Expect = 0.006
Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 13/167 (7%)
Query: 10 DEPAGHRLSQEEILGSTRLVSQGL-------EALRSEHQAVLQSLSQTIECLQQGGHEEG 62
+E RL +E + GS V + L E L +E QA+L + +T+ G ++
Sbjct: 897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLA-KETLTGELAGLRQQI 955
Query: 63 LVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDE 122
+ ++ L + + +L +E + +L + E + Q+L+ + +E L E
Sbjct: 956 IATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRE---LEAE 1012
Query: 123 LAGTQQRLQR-SEQAVAQLEEEKKHL-EFLGQLRQYDEDGHTSEEKE 167
A Q +LQR E+ +A+LE EK+ L E + L+Q ++G E E
Sbjct: 1013 RAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESE 1059
Score = 37.4 bits (85), Expect = 0.017
Identities = 31/161 (19%), Positives = 67/161 (41%), Gaps = 8/161 (4%)
Query: 33 LEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQV-MLAL 91
LE L + + + L + E L + + ++ + ++ ++ E G E ++ M L
Sbjct: 668 LEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKL 727
Query: 92 ASHLSTVESEKQKLRAQVRRLCQEN-------QWLRDELAGTQQRLQRSEQAVAQLEEEK 144
+ ++++ KL A L Q+ L +E + Q R +++EQ EE+
Sbjct: 728 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 787
Query: 145 KHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEE 185
+ LE L ++ G + + +++L+ P E
Sbjct: 788 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHE 828
Score = 36.2 bits (82), Expect = 0.039
Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 4/132 (3%)
Query: 63 LVHEKARQLRRSMENIELGLSEAQVMLA-LASHLSTVESEKQKLRAQVRRLCQENQWLRD 121
L+H + + ++++ +Q +L L LS ESE++ L Q++RL +
Sbjct: 523 LIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQ 582
Query: 122 ELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSL---DDL 178
Q+ +QR A L EK +L Q+ Q + E ++ A ++ L D
Sbjct: 583 AHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDR 642
Query: 179 FPNEEEEDPSNG 190
E+E+ +G
Sbjct: 643 LEEEQEDAVQDG 654
Score = 34.7 bits (78), Expect = 0.11
Identities = 43/150 (28%), Positives = 62/150 (41%), Gaps = 26/150 (17%)
Query: 16 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 75
R S EE+ + + +L+ ++ Q L+ E G E G +LR +
Sbjct: 1216 RRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAG-------ELRTGL 1268
Query: 76 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 135
+ +E EA+ E Q+LR Q++ L EN L ELA Q RL E+
Sbjct: 1269 QEVERSRLEAR-------------RELQELRRQMKMLDSENTRLGRELAELQGRLALGER 1315
Query: 136 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEE 165
A E++ E LG LRQ G S E
Sbjct: 1316 A-----EKESRRETLG-LRQRLLKGEASLE 1339
Score = 32.3 bits (72), Expect = 0.56
Identities = 33/145 (22%), Positives = 62/145 (42%), Gaps = 5/145 (3%)
Query: 8 QRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEK 67
Q + G + +++LG+ R E+ R + LQ L + Q + ++
Sbjct: 534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 593
Query: 68 ARQ----LRRSMENIELGLSEAQVMLA-LASHLSTVESEKQKLRAQVRRLCQENQWLRDE 122
R L R N+ L AQ L +++ +++LR Q RL +E + +
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 123 LAGTQQRLQRSEQAVAQLEEEKKHL 147
A ++ L+RS + + QLE ++ L
Sbjct: 654 GARVRRELERSHRQLEQLEGKRSVL 678
Score = 31.6 bits (70), Expect = 0.96
Identities = 46/172 (26%), Positives = 67/172 (38%), Gaps = 34/172 (19%)
Query: 5 VLGQRDEPAGHRLS----QEEILGSTRLVSQG----LEALRSEHQAVLQSLSQTIECLQQ 56
VL +R + A LS Q LG +G LE R E + LQ L + + Q+
Sbjct: 1765 VLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQE 1824
Query: 57 GG-----------HEEGLVHEKARQLRRSMENIELGLSEAQVM--------LALASHLST 97
G E L+ E+ L+R++ +E E + +AL L
Sbjct: 1825 GEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDK 1884
Query: 98 VESEKQKLRAQVRRLCQENQWLRD-------ELAGTQQRLQRSEQAVAQLEE 142
VE EK + RL E L ELA Q+++Q+ E V LE+
Sbjct: 1885 VEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQ 1936
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/170 (24%), Positives = 78/170 (45%), Gaps = 7/170 (4%)
Query: 29 VSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSE-AQV 87
+++ L+ E+ ++ + LQ + LV A + +E ++ + E A+
Sbjct: 2138 IAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARS 2197
Query: 88 MLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKK-H 146
+ L T+ SEK+ L Q++ + L L+ + L+ EQA Q++EE K
Sbjct: 2198 LKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTA 2257
Query: 147 LEFL-GQLRQYDE--DGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR 193
+E L QL++ +E +++ AT+ SLD P EEE N + +
Sbjct: 2258 VEMLQNQLKELNEAVAALCGDQEIMKATEQSLDP--PIEEEHQLRNSIEK 2305
Score = 30.4 bits (67), Expect = 2.1
Identities = 59/239 (24%), Positives = 95/239 (39%), Gaps = 40/239 (16%)
Query: 33 LEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLA-- 90
LE L+S ++ + L T + + K +L+R M + +E Q L+
Sbjct: 2583 LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGE 2642
Query: 91 ---LASHLSTVESEKQKLRAQVRRLCQENQWLRDEL------AGTQQRLQRSEQAVAQL- 140
LA L + E + + Q++ L EN L+ L ++ R E A QL
Sbjct: 2643 KNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 2702
Query: 141 --EEEKKHLEFLGQL-RQYDEDGHTSEEK----EGDATKDSLD-DLFPNEEEEDPSNGLS 192
E EKKH L +QY+ + T EK E + L+ DL + +EE L+
Sbjct: 2703 LHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-----LN 2757
Query: 193 RGQGATAAQQGGYEIPARLRTLHNLVIQYA---------AQGRYEVAVPLCKQALEDLE 242
AT +I L+ ++Y AQG+ ++ + CKQ E+ E
Sbjct: 2758 NSLKATT------QILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKE 2810
Score = 30.0 bits (66), Expect = 2.8
Identities = 24/113 (21%), Positives = 50/113 (44%), Gaps = 12/113 (10%)
Query: 44 LQSLSQTIECLQQGGHE-----EGLVHEKARQLRRSMENIELGLSEA-----QVMLALAS 93
L+ L++ + C +Q E + EK ++ + + + Q+ L
Sbjct: 364 LKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQ 423
Query: 94 HLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQA--VAQLEEEK 144
L ++ L+A++ +L Q L + L +Q+L R+EQA +Q++E +
Sbjct: 424 ELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE 476
Score = 28.9 bits (63), Expect = 6.2
Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 21/129 (16%)
Query: 30 SQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGL----VHEKARQLRRSMENIELGLSEA 85
S+ L+A SE ++S+ +E E L E+ QLRR +E + + +
Sbjct: 2072 SESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEAD 2131
Query: 86 QVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ----AVAQLE 141
+ L E K++ R EN L+D++ ++ LQ SE+ + E
Sbjct: 2132 E-----KKQLHIAEKLKERER--------ENDSLKDKVENLERELQMSEENQELVILDAE 2178
Query: 142 EEKKHLEFL 150
K +E L
Sbjct: 2179 NSKAEVETL 2187
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/167 (25%), Positives = 76/167 (45%), Gaps = 14/167 (8%)
Query: 11 EPAGHRLSQEEILGST--RLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKA 68
E H + + LG + +L +Q E L E A + Q + + H +
Sbjct: 121 EEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQD---ETNHLRKELESVG 177
Query: 69 RQLRRSMENIE-LGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDE---LA 124
RQL+ +EN + L L + L + ++++LR Q RLC++ + LR++ L
Sbjct: 178 RQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLR 237
Query: 125 GTQQRLQRSEQAVAQLEE-----EKKHLEFLGQLRQYDEDGHTSEEK 166
++RL E+ + + EE E++ E +LR+ +E H EE+
Sbjct: 238 EQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEER 284
Score = 37.0 bits (84), Expect = 0.023
Identities = 46/215 (21%), Positives = 91/215 (42%), Gaps = 15/215 (6%)
Query: 15 HRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRS 74
+R +E + + + E LR + + + + + E ++ +E + E+ +LR
Sbjct: 194 NRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREH 253
Query: 75 MENI---ELGLSEAQVMLA-----LASHLSTVESEKQKLRAQVRRLCQENQWLRDE---L 123
E + E L E + L L + ++++LR Q RLC++ + LR++ L
Sbjct: 254 EERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERL 313
Query: 124 AGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEE 183
++RL+ E+ + + E+ L ++ + E EE+E ++ L + E
Sbjct: 314 CEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLE----EV 369
Query: 184 EEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLV 218
EE R Q QQ + RLR L ++
Sbjct: 370 EELLEQERLRQQDERLWQQETLQELERLRELERML 404
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/165 (23%), Positives = 79/165 (47%), Gaps = 12/165 (7%)
Query: 37 RSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALASHL- 95
+ E Q LQ+L +E L+Q ++ LV + ++R +E ++ + + +LAS L
Sbjct: 1790 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLK 1849
Query: 96 ----STVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEF-L 150
E Q++ A+ R ++N+ L+ +L T++ + + A+ +K LE L
Sbjct: 1850 ENMEKLTEERDQRIAAENREK-EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDL 1908
Query: 151 GQLRQYDE----DGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 191
L ++ D + ++ GD + +++D ++E ED N L
Sbjct: 1909 ESLEAANQSLQADLKLAFKRIGD-LQAAIEDEMESDENEDLINSL 1952
Score = 30.8 bits (68), Expect = 1.6
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 22/172 (12%)
Query: 60 EEGLVHEKARQLRRSMENIELGLSE-AQVMLALASHLSTVESEKQKLRAQVRRLCQENQW 118
E+ ++ +A L++ +E ++ ++ Q +++L + L + S++ K A + ++ ++ +
Sbjct: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
Query: 119 LR----------DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEG 168
L DE AGT Q L EQA +LE E + + D E ++
Sbjct: 1547 LEAKVKDQEEELDEQAGTIQML---EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQS 1603
Query: 169 DATKDSLDDLFPNEEEEDPSNGLS-----RGQGATAAQQ---GGYEIPARLR 212
K ++ EE ED L G+ AT + Q +E RLR
Sbjct: 1604 CQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLR 1655
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 5/148 (3%)
Query: 66 EKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAG 125
EK + RR E +E E + E E ++L A+ R +E + E
Sbjct: 495 EKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERA 554
Query: 126 TQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP----N 181
++R + +E+A Q EEE + E ++RQ E EE+E K L+++
Sbjct: 555 LRER-EEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRT 613
Query: 182 EEEEDPSNGLSRGQGATAAQQGGYEIPA 209
E + ++ G A A GG E+ A
Sbjct: 614 EATDKKTSDQRNGDIAKGALTGGTEVSA 641
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/145 (22%), Positives = 69/145 (47%), Gaps = 11/145 (7%)
Query: 19 QEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGH--------EEGLVH--EKA 68
+EEI+ T+LV QG +H + L E ++ E L E+
Sbjct: 124 KEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQ 183
Query: 69 RQLRRSMENIELGLSEAQVMLALASHLSTVE-SEKQKLRAQVRRLCQENQWLRDELAGTQ 127
++ RS E E +S+ Q + + ++ E +K+KL +++++ + + E+ Q
Sbjct: 184 QETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQ 243
Query: 128 QRLQRSEQAVAQLEEEKKHLEFLGQ 152
Q +Q+S++ + +LE++ K + L +
Sbjct: 244 QYVQKSKEELQKLEQQLKEQKILNE 268
>gi|31542661 transmembrane protein 57 [Homo sapiens]
Length = 664
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/77 (28%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
Query: 70 QLRRSMENIELGLSEA-QVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQ 128
+L + ++ ++ L + QV L S +S++ S ++ +R+++ +L QEN+ L+++L Q
Sbjct: 385 RLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQ 444
Query: 129 RLQRSEQAVAQLEEEKK 145
Q+ +Q ++QLE++ K
Sbjct: 445 MKQKDKQNISQLEKKLK 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,794,234
Number of Sequences: 37866
Number of extensions: 585935
Number of successful extensions: 5151
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 489
Number of HSP's that attempted gapping in prelim test: 3796
Number of HSP's gapped (non-prelim): 1593
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.