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Search of human proteins with 19923727
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923727 minichromosome maintenance complex component 8
isoform 1 [Homo sapiens]
(840 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923727 minichromosome maintenance complex component 8 isofo... 1670 0.0
gi|33469924 minichromosome maintenance complex component 8 isofo... 1626 0.0
gi|33356547 minichromosome maintenance complex component 2 [Homo... 307 3e-83
gi|33469919 minichromosome maintenance complex component 4 [Homo... 294 2e-79
gi|33469917 minichromosome maintenance complex component 4 [Homo... 294 2e-79
gi|33469968 minichromosome maintenance complex component 7 isofo... 262 1e-69
gi|7427519 minichromosome maintenance complex component 6 [Homo ... 256 8e-68
gi|23510448 minichromosome maintenance complex component 5 [Homo... 245 1e-64
gi|6631095 minichromosome maintenance complex component 3 [Homo ... 239 8e-63
gi|33469922 minichromosome maintenance complex component 7 isofo... 237 4e-62
gi|23397546 minichromosome maintenance complex component 9 [Homo... 124 4e-28
gi|209954823 minichromosome maintenance complex component-like i... 37 0.058
gi|209954821 minichromosome maintenance complex component-like i... 36 0.17
gi|90265805 phospholipase C, delta 1 isoform 2 [Homo sapiens] 35 0.38
gi|195972883 phospholipase C, delta 1 isoform 1 [Homo sapiens] 35 0.38
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 32 3.2
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 32 3.2
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 32 3.2
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 32 3.2
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 32 3.2
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 32 3.2
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 32 3.2
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] 32 3.2
gi|30061565 La ribonucleoprotein domain family member 2 isoform ... 32 3.2
gi|30061569 La ribonucleoprotein domain family member 2 isoform ... 32 3.2
gi|30061567 La ribonucleoprotein domain family member 2 isoform ... 32 3.2
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 32 3.2
gi|7242140 ClpX caseinolytic protease X homolog [Homo sapiens] 31 4.2
gi|40255119 RAS and EF-hand domain containing [Homo sapiens] 31 4.2
gi|11141871 J domain containing protein 1 isoform a [Homo sapiens] 31 4.2
>gi|19923727 minichromosome maintenance complex component 8 isoform
1 [Homo sapiens]
Length = 840
Score = 1670 bits (4324), Expect = 0.0
Identities = 840/840 (100%), Positives = 840/840 (100%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK 60
MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK
Sbjct: 1 MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK 60
Query: 61 TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS 120
TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS
Sbjct: 61 TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS 120
Query: 121 ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG 180
ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG
Sbjct: 121 ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG 180
Query: 181 LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF 240
LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF
Sbjct: 181 LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF 240
Query: 241 LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD 300
LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD
Sbjct: 241 LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD 300
Query: 301 QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEAN 360
QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEAN
Sbjct: 301 QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEAN 360
Query: 361 SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV 420
SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV
Sbjct: 361 SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV 420
Query: 421 KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN 480
KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN
Sbjct: 421 KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN 480
Query: 481 TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS 540
TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS
Sbjct: 481 TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS 540
Query: 541 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 600
LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH
Sbjct: 541 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 600
Query: 601 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 660
HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP
Sbjct: 601 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 660
Query: 661 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 720
IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT
Sbjct: 661 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 720
Query: 721 EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI 780
EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI
Sbjct: 721 EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI 780
Query: 781 SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM 840
SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM
Sbjct: 781 SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM 840
>gi|33469924 minichromosome maintenance complex component 8 isoform
2 [Homo sapiens]
Length = 824
Score = 1626 bits (4210), Expect = 0.0
Identities = 824/840 (98%), Positives = 824/840 (98%), Gaps = 16/840 (1%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK 60
MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK
Sbjct: 1 MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK 60
Query: 61 TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS 120
TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS
Sbjct: 61 TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS 120
Query: 121 ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG 180
ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG
Sbjct: 121 ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG 180
Query: 181 LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF 240
LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF
Sbjct: 181 LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF 240
Query: 241 LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD 300
LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD
Sbjct: 241 LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD 300
Query: 301 QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEAN 360
QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEE AN
Sbjct: 301 QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEE----------------AN 344
Query: 361 SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV 420
SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV
Sbjct: 345 SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV 404
Query: 421 KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN 480
KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN
Sbjct: 405 KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN 464
Query: 481 TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS 540
TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS
Sbjct: 465 TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS 524
Query: 541 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 600
LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH
Sbjct: 525 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 584
Query: 601 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 660
HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP
Sbjct: 585 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 644
Query: 661 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 720
IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT
Sbjct: 645 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 704
Query: 721 EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI 780
EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI
Sbjct: 705 EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI 764
Query: 781 SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM 840
SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM
Sbjct: 765 SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM 824
>gi|33356547 minichromosome maintenance complex component 2 [Homo
sapiens]
Length = 904
Score = 307 bits (786), Expect = 3e-83
Identities = 227/757 (29%), Positives = 372/757 (49%), Gaps = 88/757 (11%)
Query: 7 GRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQ 66
GRG GR R G E E RP + +R +E + + M
Sbjct: 125 GRGLGRMR---------RGLLYDSDEEDEERPARKRRQVERATEDGEE-------DEEMI 168
Query: 67 STLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYD----KDEI-----ER 117
+++ KG + E S + P +E F+ F H+D + K+ I E
Sbjct: 169 ESIENLEDLKGHSV--REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKEN 226
Query: 118 KGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQA 177
+ S++V++++L V +A L +AP + L A +V+ ++
Sbjct: 227 RESLVVNYEDLAAREHV------LAYFLPEAPAELLQIFDEAALEVVLAMYPKY------ 274
Query: 178 QEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTK 237
+ ++N HIH R+ + + +L+++R + + I G V + + P +
Sbjct: 275 -DRITN---------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSM 324
Query: 238 MAFLCAACGEIQS-FPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQEL 296
+ + C C + F + P CP G + T+ ++Q I+IQE
Sbjct: 325 VKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEE---TIYQNYQRIRIQE- 380
Query: 297 MSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNK-NDKCMFLL 355
S + AGR+PR+ + L+ DLVDSC PGD + +TGI N +GS N N +F
Sbjct: 381 -SPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYH--NNYDGSLNTANGFPVFAT 437
Query: 356 YIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIF 415
I AN ++ + E + +D+ I + ++ + + I S+ P I+
Sbjct: 438 VILANHVAKKDNKVAVG-----------ELTDEDVKMITSLSKDQQIGEKIFASIAPSIY 486
Query: 416 GHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGV 475
GHE +K GLALALFGG K K+++ RGD ++L+ GDPG KSQ L+ V+ R +
Sbjct: 487 GHEDIKRGLALALFGGEPKNPGGKHKV--RGDINVLLCGDPGTAKSQFLKYIEKVSSRAI 544
Query: 476 YVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAM 534
+ G + GLT + + S ++ LEAGALVL D+G+C IDEFDKM +Q + + EAM
Sbjct: 545 FTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAM 604
Query: 535 EQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILL 594
EQQSIS++KAG+V SL AR ++IAAANP+GG Y+ + T SEN+ + ++SRFD++ ++
Sbjct: 605 EQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVR 664
Query: 595 DTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVP 654
DT + D +L+ V+ + + SN + + +
Sbjct: 665 DTVDPVQDEMLARFVVG--------------SHVRHHPSNKEEEGLANGSAAEPAMPNTY 710
Query: 655 GETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLE 714
G ++P+P ++L+KYI YA++ V+P+L+ + Y +LRK+S S PIT R +E
Sbjct: 711 G--VEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIE 768
Query: 715 SLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGT 751
S+IR+ EA AR+ LR+ ++D + +M S + T
Sbjct: 769 SMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDT 805
>gi|33469919 minichromosome maintenance complex component 4 [Homo
sapiens]
Length = 863
Score = 294 bits (753), Expect = 2e-79
Identities = 199/650 (30%), Positives = 318/650 (48%), Gaps = 56/650 (8%)
Query: 194 IHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPL 253
I R +N ++N+ + I + G V+R S + P + F C C +
Sbjct: 258 IQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEM 317
Query: 254 PDGKYSLPTKCPVPVCRGRSFTALRSSPL---TVTMDWQSIKIQELMSDDQREAGRIPRT 310
G+ + P+ C GR T + + ++ D Q IK+QE S + AG+ P T
Sbjct: 318 DRGRIAEPSVC------GRCHTTHSMALIHNRSLFSDKQMIKLQE--SPEDMPAGQTPHT 369
Query: 311 IECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKT 370
+ +DLVD PGD V +TGI + R N K ++ +I+ + ++
Sbjct: 370 VILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRL 429
Query: 371 KSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFG 430
++ + + FS K + ++E+ + ++++ + ++L P I+ HE +K G+ L LFG
Sbjct: 430 HGLDEEAEQKL---FSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFG 486
Query: 431 GSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVT 490
G++K R R + +IL+ GDPG KSQ+LQ N+ PRG Y G ++ GLT
Sbjct: 487 GTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAY 546
Query: 491 LSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAGVVCS 549
+ KD + L+ GALVL D GIC IDEFDKM +++L E MEQQ++S+AKAG++C
Sbjct: 547 VMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQ 606
Query: 550 LPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHV 609
L ARTS++AAANP+ +N KT EN+++ LLSRFDL+F+LLD +E +D L+ H+
Sbjct: 607 LNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHL 666
Query: 610 IAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKY 669
+A L SE+ E L + +L+ Y
Sbjct: 667 VA--------------------------LYYQSEEQAEEEL----------LDMAVLKDY 690
Query: 670 IGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELR 729
I YA + PRLS EA++ L + Y+++RK RQLESLIRL EA A++ L
Sbjct: 691 IAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLS 750
Query: 730 EEATKEDAEDIVEIMKYSMLGTYSD-EFGNLDFERSQHGSGMSNRSTAKRFISALNN-VA 787
+ D E+ + + ++ + +D G +D G ++R + AL +
Sbjct: 751 NKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLIL 810
Query: 788 ERTYNNIFQFHQL-RQIAKELNIQVAD--FENFIGSLNDQGYLLKKGPKV 834
+ ++ QL I + +I + FE + +L D +L G V
Sbjct: 811 SKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTV 860
>gi|33469917 minichromosome maintenance complex component 4 [Homo
sapiens]
Length = 863
Score = 294 bits (753), Expect = 2e-79
Identities = 199/650 (30%), Positives = 318/650 (48%), Gaps = 56/650 (8%)
Query: 194 IHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPL 253
I R +N ++N+ + I + G V+R S + P + F C C +
Sbjct: 258 IQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEM 317
Query: 254 PDGKYSLPTKCPVPVCRGRSFTALRSSPL---TVTMDWQSIKIQELMSDDQREAGRIPRT 310
G+ + P+ C GR T + + ++ D Q IK+QE S + AG+ P T
Sbjct: 318 DRGRIAEPSVC------GRCHTTHSMALIHNRSLFSDKQMIKLQE--SPEDMPAGQTPHT 369
Query: 311 IECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKT 370
+ +DLVD PGD V +TGI + R N K ++ +I+ + ++
Sbjct: 370 VILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRL 429
Query: 371 KSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFG 430
++ + + FS K + ++E+ + ++++ + ++L P I+ HE +K G+ L LFG
Sbjct: 430 HGLDEEAEQKL---FSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFG 486
Query: 431 GSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVT 490
G++K R R + +IL+ GDPG KSQ+LQ N+ PRG Y G ++ GLT
Sbjct: 487 GTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAY 546
Query: 491 LSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAGVVCS 549
+ KD + L+ GALVL D GIC IDEFDKM +++L E MEQQ++S+AKAG++C
Sbjct: 547 VMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQ 606
Query: 550 LPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHV 609
L ARTS++AAANP+ +N KT EN+++ LLSRFDL+F+LLD +E +D L+ H+
Sbjct: 607 LNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHL 666
Query: 610 IAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKY 669
+A L SE+ E L + +L+ Y
Sbjct: 667 VA--------------------------LYYQSEEQAEEEL----------LDMAVLKDY 690
Query: 670 IGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELR 729
I YA + PRLS EA++ L + Y+++RK RQLESLIRL EA A++ L
Sbjct: 691 IAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLS 750
Query: 730 EEATKEDAEDIVEIMKYSMLGTYSD-EFGNLDFERSQHGSGMSNRSTAKRFISALNN-VA 787
+ D E+ + + ++ + +D G +D G ++R + AL +
Sbjct: 751 NKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLIL 810
Query: 788 ERTYNNIFQFHQL-RQIAKELNIQVAD--FENFIGSLNDQGYLLKKGPKV 834
+ ++ QL I + +I + FE + +L D +L G V
Sbjct: 811 SKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTV 860
>gi|33469968 minichromosome maintenance complex component 7 isoform
1 [Homo sapiens]
Length = 719
Score = 262 bits (669), Expect = 1e-69
Identities = 177/548 (32%), Positives = 278/548 (50%), Gaps = 63/548 (11%)
Query: 207 LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPV 266
++ VRA+ GK + +RG V RVS +KP + C CG P+ + CP
Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208
Query: 267 PVCR-----GRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 321
C+ GR + R S + +Q +K+QE DQ G IPR+I + +
Sbjct: 209 QECQTNRSGGRLYLQTRGSRF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 263
Query: 322 SCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGM 381
PGD V++TGI + G R + Y+EA+ I + KS +D G
Sbjct: 264 IAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSETYLEAHRIV----KMNKSEDDESGAGE 318
Query: 382 LMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR 441
L L+ + AEE+ ++ + S+ P I+GHE VK L L L GG +
Sbjct: 319 LTREELRQI-------AEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQ---SPRG 368
Query: 442 IPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFA 501
+ IRG+ +I ++GDPG+ KSQ+L +APR Y G ++ GLT + +DS SG+
Sbjct: 369 MKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELT 428
Query: 502 LEAGALVLGDQGICGIDEFDKMGN-QHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAA 560
LE GALVL DQG+C IDEFDKM A+ E MEQQ+IS+AKAG++ +L AR SI+AAA
Sbjct: 429 LEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAA 488
Query: 561 NPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRTI 620
NP G YN +++ +N+++ +ALLSRFDL++++ D P+ +D L++H+ + ++
Sbjct: 489 NPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQ-- 546
Query: 621 SSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQYVYPR 680
P +P+ +L+R+YI R+ P
Sbjct: 547 ---------------------------------PPSQFEPLDMKLMRRYIAMCRE-KQPM 572
Query: 681 LSTEAARVLQDFYLELRKQSQRLNSSPITT-RQLESLIRLTEARARLELREEATKEDAED 739
+ A + Y+E+R+++ + T+ R L +++RL+ A ARL + + KED +
Sbjct: 573 VPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNE 632
Query: 740 IVEIMKYS 747
+ +M+ S
Sbjct: 633 AIRLMEMS 640
>gi|7427519 minichromosome maintenance complex component 6 [Homo
sapiens]
Length = 821
Score = 256 bits (653), Expect = 8e-68
Identities = 182/624 (29%), Positives = 309/624 (49%), Gaps = 85/624 (13%)
Query: 206 QLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCP 265
+++ + ++ G + G VVR + P FLC C + KY+ P C
Sbjct: 122 KIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICR 181
Query: 266 VPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVP 325
PVC R L ++ +D+Q ++IQE ++ R G IPR++E L + V+S
Sbjct: 182 NPVCANRRRFLLDTNKSRF-VDFQKVRIQETQAELPR--GSIPRSLEVILRAEAVESAQA 238
Query: 326 GDTVTITGIVKV-----------SNAEEGSR---------------------NKNDKCMF 353
GD TG + V + AE SR + + + +F
Sbjct: 239 GDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVF 298
Query: 354 LLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPV 413
L A + G++ + E + + + ++K+ + E+ ++NL+ + SL P
Sbjct: 299 LACCVAPTNPRFGGKELRDEEQTAE-SIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPT 357
Query: 414 IFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPR 473
I G++ VK G+ L LFGG K + + RGD ++ +VGDP KSQ L+ +PR
Sbjct: 358 IHGNDEVKRGVLLMLFGGVPKTTGEGTSL--RGDINVCIVGDPSTAKSQFLKHVEEFSPR 415
Query: 474 GVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLE 532
VY G ++ +GLT + +D S +F +EAGAL+L D G+C IDEFDKM + Q A+ E
Sbjct: 416 AVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHE 475
Query: 533 AMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFI 592
AMEQQ+IS+ KAGV +L ARTSI+AAANP+ GHY+++K++ +N+ + + ++SRFDL FI
Sbjct: 476 AMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFI 535
Query: 593 LLDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKV 652
L+D NE D+ ++ ++ + + + +I R+ S D
Sbjct: 536 LVDECNEVTDYAIARRIVDLHSRIEESID-----RVYSLDD------------------- 571
Query: 653 VPGETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQ---SQRLNSSPIT 709
+R+Y+ +ARQ+ P++S E+ + + Y LR++ +S IT
Sbjct: 572 -------------IRRYLLFARQF-KPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRIT 617
Query: 710 TRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYS-----DEFGNLDFERS 764
RQLES+IRL+EA AR+ +E + ++ ++ S++ + D+ + E
Sbjct: 618 VRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVD 677
Query: 765 QHGSGMSNRSTAKRFISALNNVAE 788
+ G++ + + ++ +N E
Sbjct: 678 EGAGGINGHADSPAPVNGINGYNE 701
>gi|23510448 minichromosome maintenance complex component 5 [Homo
sapiens]
Length = 734
Score = 245 bits (625), Expect = 1e-64
Identities = 178/565 (31%), Positives = 291/565 (51%), Gaps = 70/565 (12%)
Query: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE----IQSFPLPDGKYSL 260
+ +++++++ + + G ++ S ++ T+++ C +C I P +G Y+L
Sbjct: 135 SSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEG-YAL 193
Query: 261 PTKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECEL 315
P KC P C + + V D+Q++K+QEL D G +PR ++
Sbjct: 194 PRKCNTDQAGRPKCPLDPYFIMPDKCKCV--DFQTLKLQEL--PDAVPHGEMPRHMQLYC 249
Query: 316 VHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLL---YIEANSISNSKGQKTKS 372
L D VPG+ VTI GI + + D+ + YI I +
Sbjct: 250 DRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGI--------QV 301
Query: 373 SEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGS 432
DG S ++ + + A N++++I S+ P IFG +K +A LFGGS
Sbjct: 302 DTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGS 361
Query: 433 QKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLS 492
+K D + RGD ++L++GDPG KSQ+L+ +P GVY G ++ +GLT ++
Sbjct: 362 RKRLPDG--LTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVM 419
Query: 493 KDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLP 551
+D SS +F +E GA+VL D G+ IDEFDKM + A+ EAMEQQ+IS+AKAG+ +L
Sbjct: 420 RDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLN 479
Query: 552 ARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIA 611
+R S++AAAN V G +++ K +N+ +LSRFD++FI+ D NE D +L++HVI
Sbjct: 480 SRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVIT 538
Query: 612 IRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIG 671
+ +S+ T + + V GE I L+K+I
Sbjct: 539 LH------VSALT------------------------QTQAVEGE----IDLAKLKKFIA 564
Query: 672 YARQYVYPRLSTEAARVLQDFYLELR-------KQSQRLNSSPITTRQLESLIRLTEARA 724
Y R PRLS EAA L++ Y+ +R + S R +S PIT RQLE+++R+ EA +
Sbjct: 565 YCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALS 624
Query: 725 RLELREEATKEDAEDIVEIMKYSML 749
+++L+ AT+ D E+ + + + S L
Sbjct: 625 KMKLQPFATEADVEEALRLFQVSTL 649
>gi|6631095 minichromosome maintenance complex component 3 [Homo
sapiens]
Length = 808
Score = 239 bits (610), Expect = 8e-63
Identities = 172/547 (31%), Positives = 276/547 (50%), Gaps = 37/547 (6%)
Query: 219 IALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPD--GKYSLPTKCPVPVCRGRSFTA 276
+ + G V + S ++P + C A + D + P+ P +
Sbjct: 125 VCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPL 184
Query: 277 LRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVK 336
L+V D Q+I IQE+ ++ AG++PR+++ L DLVD PGD V + G +
Sbjct: 185 ETEYGLSVYKDHQTITIQEM--PEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYR 242
Query: 337 VSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEI 396
++G L+ +S Q + S+ED K + KD+
Sbjct: 243 CLPGKKGGYTSGTFRTVLIACNVKQMSKD-AQPSFSAEDIAKIKKFSKTRSKDI------ 295
Query: 397 QAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDP 456
F + SL P I GH+ VK + L GG ++ D +N IRGD +IL++GDP
Sbjct: 296 ------FDQLAKSLAPSIHGHDYVKKAILCLLLGGVER--DLENGSHIRGDINILLIGDP 347
Query: 457 GLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICG 516
+ KSQ+L+ APR + G ++ GLT ++ D +G+ LEAGA+VL D+G+
Sbjct: 348 SVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVC 407
Query: 517 IDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSE 575
IDEFDKM + + A+ E MEQ +++AKAG+ L AR S++AAANPV G Y++ KT E
Sbjct: 408 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPME 467
Query: 576 NLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAI--------RAGKQRTISSATVAR 627
N+ + +LLSRFDL+FI+LD + D +S+HV+ + + G + SA V
Sbjct: 468 NIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSA-VDI 526
Query: 628 MNSQDSNTSVLEVVSEKPLSERLKVVPG---ETIDPIPHQLLRKYIGYARQYVYPRLSTE 684
+ + D N S + + + ++ G + + ++KYI A+ + P L+ E
Sbjct: 527 LATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPVLTQE 585
Query: 685 AARVLQDFYLELRKQ----SQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDI 740
+A + + Y LR Q S +SP+T R LE+LIRL A A+ + + +DAE+
Sbjct: 586 SATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEA 645
Query: 741 VEIMKYS 747
VE+++Y+
Sbjct: 646 VELVQYA 652
>gi|33469922 minichromosome maintenance complex component 7 isoform
2 [Homo sapiens]
Length = 543
Score = 237 bits (604), Expect = 4e-62
Identities = 164/515 (31%), Positives = 259/515 (50%), Gaps = 63/515 (12%)
Query: 240 FLCAACGEIQSFPLPDGKYSLPTKCPVPVCR-----GRSFTALRSSPLTVTMDWQSIKIQ 294
+ C CG P+ + CP C+ GR + R S + +Q +K+Q
Sbjct: 6 YTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRF---IKFQEMKMQ 62
Query: 295 ELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFL 354
E DQ G IPR+I + + PGD V++TGI + G R +
Sbjct: 63 E--HSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSE 119
Query: 355 LYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVI 414
Y+EA+ I + KS +D G L L+ + AEE+ ++ + S+ P I
Sbjct: 120 TYLEAHRIV----KMNKSEDDESGAGELTREELRQI-------AEEDFYEKLAASIAPEI 168
Query: 415 FGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRG 474
+GHE VK L L L GG + + IRG+ +I ++GDPG+ KSQ+L +APR
Sbjct: 169 YGHEDVKKALLLLLVGGVDQ---SPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRS 225
Query: 475 VYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN-QHQALLEA 533
Y G ++ GLT + +DS SG+ LE GALVL DQG+C IDEFDKM A+ E
Sbjct: 226 QYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEV 285
Query: 534 MEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFIL 593
MEQQ+IS+AKAG++ +L AR SI+AAANP G YN +++ +N+++ +ALLSRFDL++++
Sbjct: 286 MEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLI 345
Query: 594 LDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVV 653
D P+ +D L++H+ + ++
Sbjct: 346 QDRPDRDNDLRLAQHITYVHQHSRQ----------------------------------- 370
Query: 654 PGETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITT-RQ 712
P +P+ +L+R+YI R+ P + A + Y+E+R+++ + T+ R
Sbjct: 371 PPSQFEPLDMKLMRRYIAMCRE-KQPMVPESLADYITAAYVEMRREAWASKDATYTSART 429
Query: 713 LESLIRLTEARARLELREEATKEDAEDIVEIMKYS 747
L +++RL+ A ARL + + KED + + +M+ S
Sbjct: 430 LLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
>gi|23397546 minichromosome maintenance complex component 9 [Homo
sapiens]
Length = 391
Score = 124 bits (311), Expect = 4e-28
Identities = 99/317 (31%), Positives = 153/317 (48%), Gaps = 48/317 (15%)
Query: 193 HIHARVYNYEPLTQLKNV---RANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQ 249
++HAR+ +L + G ++++ GTV+R S +K L + ++C C +
Sbjct: 95 NLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVF 154
Query: 250 SFPLPDGKYSL---PTKCP-VPVCRGRSFTALR--SSPLTVTMDWQSIKIQELMSDDQRE 303
+Y P+ CP + C FT L SS T D+Q IKIQE + +
Sbjct: 155 VIKADFEQYYTFCRPSSCPSLESCDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQ--RLS 212
Query: 304 AGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKND-KCMFLLYIEANSI 362
G IPR+++ L DLVDSC GD +TI GIV + + D +C + ++AN I
Sbjct: 213 VGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVM----QRWKPFQQDVRCEVEIVLKANYI 268
Query: 363 SNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLF------------KLIVNSL 410
+ Q + G++M+ +E+Q E F +I+ SL
Sbjct: 269 QVNNEQSS---------GIIMD---------EEVQKEFEDFWEYYKSDPFAGRNVILASL 310
Query: 411 CPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNV 470
CP +FG LVK +A+ L GG Q+ D +RG+ H+L+VGDPG GKSQ L+ A +
Sbjct: 311 CPQVFGMYLVKLAVAMVLAGGIQR--TDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKI 368
Query: 471 APRGVYVCGNTTTTSGL 487
PR V G +T++G+
Sbjct: 369 TPRSVLTTGIGSTSAGI 385
>gi|209954823 minichromosome maintenance complex component-like
isoform b [Homo sapiens]
Length = 632
Score = 37.4 bits (85), Expect = 0.058
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 682 STEAARVLQDFYLELRK-QSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDI 740
S EA R+ +YL R+ ++ + S ++ L+ L+ L+EA ARL LR + KED
Sbjct: 555 SLEAERMTHGYYLASRRIRTGSVCGSKLSASALKYLVFLSEAHARLNLRNKVLKEDVLIA 614
Query: 741 VEIMKYSMLGTYSDE 755
+ + S+ Y +E
Sbjct: 615 ALLFETSLTLKYGNE 629
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 450 ILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDS-SSGDFALEAGALV 508
IL++ L ++L + N+ PRG+ ++ + TLS++ +G +++AG+ +
Sbjct: 346 ILIITSDTLLIDRLLNFSINLVPRGI----RHLVSTEIFPTLSRNKYGTGAVSIQAGSAL 401
Query: 509 LGDQGICGIDEF-----DKMGNQHQALLEA 533
L GIC I + DK+ Q Q +LE+
Sbjct: 402 LAKGGICFIGDLASHKKDKL-EQLQTVLES 430
>gi|209954821 minichromosome maintenance complex component-like
isoform a [Homo sapiens]
Length = 681
Score = 35.8 bits (81), Expect = 0.17
Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 682 STEAARVLQDFYLELRK-QSQRLNSSPITTRQLESLIRLTEARARLELREEATKED 736
S EA R+ +YL R+ ++ + S ++ L+ L+ L+EA ARL LR + KED
Sbjct: 555 SLEAERMTHGYYLASRRIRTGSVCGSKLSASALKYLVFLSEAHARLNLRNKVLKED 610
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 450 ILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDS-SSGDFALEAGALV 508
IL++ L ++L + N+ PRG+ ++ + TLS++ +G +++AG+ +
Sbjct: 346 ILIITSDTLLIDRLLNFSINLVPRGI----RHLVSTEIFPTLSRNKYGTGAVSIQAGSAL 401
Query: 509 LGDQGICGIDEF-----DKMGNQHQALLEA 533
L GIC I + DK+ Q Q +LE+
Sbjct: 402 LAKGGICFIGDLASHKKDKL-EQLQTVLES 430
>gi|90265805 phospholipase C, delta 1 isoform 2 [Homo sapiens]
Length = 756
Score = 34.7 bits (78), Expect = 0.38
Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 22/141 (15%)
Query: 689 LQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSM 748
LQ+ + ++S+++ +P + QL S+ + E R + R E ++ A D+ E +S+
Sbjct: 44 LQEDCKTIWQESRKVMRTPES--QLFSIEDIQEVR--MGHRTEGLEKFARDVPEDRCFSI 99
Query: 749 LGTYSDEFGNLDF----------------ERSQHGSGMSNRSTAKRFISALNNVAERTYN 792
+ + D+ LD + H M R + +I + A++ +
Sbjct: 100 V--FKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKD 157
Query: 793 NIFQFHQLRQIAKELNIQVAD 813
N F +L+ KELNIQV D
Sbjct: 158 NKMSFKELQNFLKELNIQVDD 178
>gi|195972883 phospholipase C, delta 1 isoform 1 [Homo sapiens]
Length = 777
Score = 34.7 bits (78), Expect = 0.38
Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 22/141 (15%)
Query: 689 LQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSM 748
LQ+ + ++S+++ +P + QL S+ + E R + R E ++ A D+ E +S+
Sbjct: 65 LQEDCKTIWQESRKVMRTPES--QLFSIEDIQEVR--MGHRTEGLEKFARDVPEDRCFSI 120
Query: 749 LGTYSDEFGNLDF----------------ERSQHGSGMSNRSTAKRFISALNNVAERTYN 792
+ + D+ LD + H M R + +I + A++ +
Sbjct: 121 V--FKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKD 178
Query: 793 NIFQFHQLRQIAKELNIQVAD 813
N F +L+ KELNIQV D
Sbjct: 179 NKMSFKELQNFLKELNIQVDD 199
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 448 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 493
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 344 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 388
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 448 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 493
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 326 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 370
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 448 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 493
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 308 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 352
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 448 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 493
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 307 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 351
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 448 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 493
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 290 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 334
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 448 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 493
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 271 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 315
>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
Length = 924
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 448 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 493
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 253 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 297
>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
Length = 960
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 448 PHILVVGDPGLGKSQMLQ--AACNVAPRGVYVCGNTTTTSGLTVTLSK 493
P ++VVGD GK+ +L+ A + PRG G T S + VTLS+
Sbjct: 289 PRVVVVGDQSAGKTSVLEMIAQARIFPRG---SGEMMTRSPVKVTLSE 333
>gi|30061565 La ribonucleoprotein domain family member 2 isoform 2
[Homo sapiens]
Length = 522
Score = 31.6 bits (70), Expect = 3.2
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 10/55 (18%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGN------FSGKWREREHRPDLSKTTGKRTS 49
+ G +RGRG GRGR RGRG GN +S ++E R D T TS
Sbjct: 144 IRGSFRGRGRGRGR----GRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTS 194
>gi|30061569 La ribonucleoprotein domain family member 2 isoform 3
[Homo sapiens]
Length = 358
Score = 31.6 bits (70), Expect = 3.2
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 10/55 (18%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGN------FSGKWREREHRPDLSKTTGKRTS 49
+ G +RGRG GRGR RGRG GN +S ++E R D T TS
Sbjct: 144 IRGSFRGRGRGRGR----GRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTS 194
>gi|30061567 La ribonucleoprotein domain family member 2 isoform 1
[Homo sapiens]
Length = 914
Score = 31.6 bits (70), Expect = 3.2
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 10/55 (18%)
Query: 1 MNGEYRGRGFGRGRFQSWKRGRGGGN------FSGKWREREHRPDLSKTTGKRTS 49
+ G +RGRG GRGR RGRG GN +S ++E R D T TS
Sbjct: 144 IRGSFRGRGRGRGR----GRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTS 194
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 31.6 bits (70), Expect = 3.2
Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 11/107 (10%)
Query: 403 FKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQ 462
++L+ +L + H V + L LF + ++ NRI + L+VG G GK
Sbjct: 2774 WELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQS 2833
Query: 463 MLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVL 509
+ + A ++ V+ +TL K DF ++ +L L
Sbjct: 2834 LTRLAAFISSMDVF-----------QITLRKGYQIQDFKMDLASLCL 2869
>gi|7242140 ClpX caseinolytic protease X homolog [Homo sapiens]
Length = 633
Score = 31.2 bits (69), Expect = 4.2
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 6/113 (5%)
Query: 449 HILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALV 508
+IL++G G GK+ + Q +C TT T V +S +A V
Sbjct: 288 NILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNV 347
Query: 509 -LGDQGICGIDEFDKMGNQ---HQALLEAME--QQSISLAKAGVVCSLPARTS 555
QGI +DE DK+G+ HQ E QQ + G + ++P + S
Sbjct: 348 EKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNS 400
>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
Length = 740
Score = 31.2 bits (69), Expect = 4.2
Identities = 32/153 (20%), Positives = 70/153 (45%), Gaps = 11/153 (7%)
Query: 677 VYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTR--QLESLIRLTEAR----ARLELRE 730
V PRL V+++F E+R QS + + I + Q ++ ++L+E R++ E
Sbjct: 158 VEPRLIQPYEHVIKNFIREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAE 217
Query: 731 EATKEDAEDIVEIMKYSMLGTYSDEFGNLD--FERSQHGSGMSNRSTAKRFISALNNVAE 788
T++D + E + Y E G+L ++ + S R + K ++AL +
Sbjct: 218 HKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALK---K 274
Query: 789 RTYNNIFQFHQLRQIAKELNIQVADFENFIGSL 821
+ Y+ + ++++ E +A ++ + +L
Sbjct: 275 QIYDLSMENQKVKKDLLEAQTNIAFLQSELDAL 307
>gi|11141871 J domain containing protein 1 isoform a [Homo sapiens]
Length = 198
Score = 31.2 bits (69), Expect = 4.2
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 33 EREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPL 92
+RE + + +T ++T ++ P+ L + +PQ+ S+ F GW L F S L
Sbjct: 132 QRERKKEELASTAEKTEQKEPKPLEKSVSPQNSDSS--GFADVNGWHLRFRWSKDAPSEL 189
Query: 93 IEKIQAFE 100
+ K + +E
Sbjct: 190 LRKFRNYE 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,955,231
Number of Sequences: 37866
Number of extensions: 1311355
Number of successful extensions: 4139
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 4034
Number of HSP's gapped (non-prelim): 65
length of query: 840
length of database: 18,247,518
effective HSP length: 111
effective length of query: 729
effective length of database: 14,044,392
effective search space: 10238361768
effective search space used: 10238361768
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.