Guide to the Human Genome
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Search of human proteins with 19923584

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923584 modulator of apoptosis 1 [Homo sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923584 modulator of apoptosis 1 [Homo sapiens]                   697   0.0  
gi|52486265 paraneoplastic antigen MA1 [Homo sapiens]                 380   e-105
gi|11464969 paraneoplastic antigen MA2 [Homo sapiens]                 302   3e-82
gi|156766066 paraneoplastic antigen like 5 [Homo sapiens]             301   4e-82
gi|156766064 paraneoplastic antigen like 5 [Homo sapiens]             301   4e-82
gi|24308384 paraneoplastic antigen like 5 [Homo sapiens]              301   4e-82
gi|142976816 paraneoplastic cancer-testis-brain antigen [Homo sa...   296   1e-80
gi|239746974 PREDICTED: hypothetical protein XP_002343900 [Homo ...   251   7e-67
gi|187607308 paraneoplastic antigen like 6A [Homo sapiens]            251   7e-67
gi|239746972 PREDICTED: hypothetical protein XP_002343899 [Homo ...   247   1e-65
gi|239746970 PREDICTED: hypothetical protein XP_002343898 [Homo ...   247   1e-65
gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [H...   157   1e-38
gi|169216516 PREDICTED: similar to paraneoplastic antigen MA1 [H...   157   1e-38
gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [H...   157   1e-38
gi|169216507 PREDICTED: similar to hCG1645335 [Homo sapiens]          151   1e-36
gi|169216732 PREDICTED: similar to hCG1645335 [Homo sapiens]          151   1e-36
gi|156766054 PNMA-like 1 isoform b [Homo sapiens]                     141   8e-34
gi|39780597 PNMA-like 1 isoform a [Homo sapiens]                      141   8e-34
gi|28557790 zinc finger, CCHC domain containing 12 [Homo sapiens]     117   2e-26
gi|221136806 zinc finger, CCHC domain containing 18 [Homo sapiens]    116   3e-26
gi|146219841 PNMA-like 2 [Homo sapiens]                                97   2e-20
gi|169216514 PREDICTED: similar to paraneoplastic antigen MA2 [H...    91   2e-18
gi|169216749 PREDICTED: similar to Putative paraneoplastic antig...    91   2e-18
gi|199559779 coiled-coil domain containing 8 [Homo sapiens]            47   2e-05
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]      38   0.012
gi|218505835 membrane-associated guanylate kinase-related  3 iso...    33   0.29 
gi|155969695 membrane-associated guanylate kinase-related  3 iso...    33   0.29 
gi|221554526 coiled-coil domain containing 42B [Homo sapiens]          30   2.5  
gi|223555921 hepatocellular carcinoma related protein 1 isoform ...    30   3.2  
gi|223555919 hepatocellular carcinoma related protein 1 isoform ...    30   3.2  

>gi|19923584 modulator of apoptosis 1 [Homo sapiens]
          Length = 351

 Score =  697 bits (1799), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE
Sbjct: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL
Sbjct: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE 180
           SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE
Sbjct: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE 180

Query: 181 FGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEV 240
           FGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEV
Sbjct: 181 FGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEV 240

Query: 241 FGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVIA 300
           FGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVIA
Sbjct: 241 FGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVIA 300

Query: 301 GAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEGNFT 351
           GAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEGNFT
Sbjct: 301 GAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEGNFT 351


>gi|52486265 paraneoplastic antigen MA1 [Homo sapiens]
          Length = 353

 Score =  380 bits (976), Expect = e-105
 Identities = 203/358 (56%), Positives = 260/358 (72%), Gaps = 13/358 (3%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M + LLEDWCRGMD+N ++ALL+ GI  +C  AEIEE LQA + P   YR+LGRMF R+E
Sbjct: 1   MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEETLQAAM-PQVSYRMLGRMFWREE 59

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           N K AL+ LT    +A +P+E+PGKGG+W+V+FKPP  D  FL RL+ FLA EG TV ++
Sbjct: 60  NAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDV 119

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALE-ALQPALQCLKYKKLRVFSGRESPEPGEE 179
           +R LG +N +  P     PEM A ML   L+  +QP ++ + YK+L +FSGR+ P PGEE
Sbjct: 120 ARVLGFQNPTPTPG----PEMPAEMLNYILDNVIQPLVESIWYKRLTLFSGRDIPGPGEE 175

Query: 180 EFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEE 239
            F  W+ HT ++++ WQV DVEKRRRL+ESLRGPA DVIR+LK NNP IT  ECL+ALE+
Sbjct: 176 TFDPWLEHTNEVLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLKALEQ 235

Query: 240 VFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVI 299
           VFG  ++ R+ Q+K+L TYQ   EKLSAYV+RLEPLLQK+V++GAI++D VNQARL+QVI
Sbjct: 236 VFGSVESSRDAQIKFLNTYQNPGEKLSAYVIRLEPLLQKVVEKGAIDKDNVNQARLEQVI 295

Query: 300 AGAVHK-TIRRELNL--PEDGPAPGFLQLLVLIKDYEAAEEEE----ALLQAILEGNF 350
           AGA H   IRR+L L    +GPAP   QLLV I++ EA EEEE     LLQ  LEG+F
Sbjct: 296 AGANHSGAIRRQLWLTGAGEGPAPNLFQLLVQIREEEAKEEEEEAEATLLQLGLEGHF 353


>gi|11464969 paraneoplastic antigen MA2 [Homo sapiens]
          Length = 364

 Score =  302 bits (773), Expect = 3e-82
 Identities = 160/342 (46%), Positives = 223/342 (65%), Gaps = 5/342 (1%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L LLEDWCR M ++ +K+L++ GI      AEI+E LQ  L  LG YRLLG++FR+ E
Sbjct: 1   MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQE 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           N    L+ L  +T  + +P E+ GKGG+W+VIFK P+ D  FL RLN FL  EG TV  +
Sbjct: 61  NANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGM 120

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE 180
            RALG E  S      + PE+ A +L QA+      L  ++Y+KLRVFSG   P P EE 
Sbjct: 121 FRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEES 180

Query: 181 FGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEV 240
           F  W+   T+++K W V + EK+R L ESLRGPALD++ +++ +NP I+V+ECL+A ++V
Sbjct: 181 FEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQV 240

Query: 241 FGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVIA 300
           FG  ++ R  QV+YL TYQ++ EK+SAYVLRLE LL++ V++ AI R   +Q RL+QV+A
Sbjct: 241 FGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMA 300

Query: 301 GAVHKTIR--RELNLPEDGPAPGFLQLLVLIKDYEAAEEEEA 340
           GA    +   R   L + GP P FL+L+ +I++    EEEEA
Sbjct: 301 GATLNQMLWCRLRELKDQGPPPSFLELMKVIRE---EEEEEA 339


>gi|156766066 paraneoplastic antigen like 5 [Homo sapiens]
          Length = 448

 Score =  301 bits (772), Expect = 4e-82
 Identities = 163/348 (46%), Positives = 230/348 (66%), Gaps = 14/348 (4%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L LLEDWC+GMDM+PRKALLI GI   CS  EI++ ++AGL PL  YR+LGRMFRR++
Sbjct: 1   MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           N K   + L    ++  +P  IPGKGG W V+ KP +PD+ FLSRLN FL  EG ++ ++
Sbjct: 61  NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 120

Query: 121 SRALG---HENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPG 177
           +RALG       SLD E  ++P++ +P        L+P  + + Y+KL+VFSG  SP PG
Sbjct: 121 ARALGCCSLPAESLDAE--VMPQVRSP-------PLEPPKESMWYRKLKVFSGTASPSPG 171

Query: 178 EEEFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQAL 237
           EE F  W+   T+++  WQV +VEKRRRLLESLRGPAL ++RVL+ NN  ITV++CL AL
Sbjct: 172 EETFEDWLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDAL 231

Query: 238 EEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQ 297
           +++FG  ++ R  Q ++L T  K  EK+S ++LRLEPLLQK V +  +   + +  RL  
Sbjct: 232 KQIFGDKEDFRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKH 291

Query: 298 VIAG-AVHKTIRRELN-LPEDGPAPGFLQLLVLIKDYEAAEEEEALLQ 343
           ++A  A+   +R +L  L + G  P FL+L+ LI+D E  E  EA+++
Sbjct: 292 LLARVAMTPALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMK 339


>gi|156766064 paraneoplastic antigen like 5 [Homo sapiens]
          Length = 448

 Score =  301 bits (772), Expect = 4e-82
 Identities = 163/348 (46%), Positives = 230/348 (66%), Gaps = 14/348 (4%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L LLEDWC+GMDM+PRKALLI GI   CS  EI++ ++AGL PL  YR+LGRMFRR++
Sbjct: 1   MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           N K   + L    ++  +P  IPGKGG W V+ KP +PD+ FLSRLN FL  EG ++ ++
Sbjct: 61  NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 120

Query: 121 SRALG---HENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPG 177
           +RALG       SLD E  ++P++ +P        L+P  + + Y+KL+VFSG  SP PG
Sbjct: 121 ARALGCCSLPAESLDAE--VMPQVRSP-------PLEPPKESMWYRKLKVFSGTASPSPG 171

Query: 178 EEEFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQAL 237
           EE F  W+   T+++  WQV +VEKRRRLLESLRGPAL ++RVL+ NN  ITV++CL AL
Sbjct: 172 EETFEDWLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDAL 231

Query: 238 EEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQ 297
           +++FG  ++ R  Q ++L T  K  EK+S ++LRLEPLLQK V +  +   + +  RL  
Sbjct: 232 KQIFGDKEDFRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKH 291

Query: 298 VIAG-AVHKTIRRELN-LPEDGPAPGFLQLLVLIKDYEAAEEEEALLQ 343
           ++A  A+   +R +L  L + G  P FL+L+ LI+D E  E  EA+++
Sbjct: 292 LLARVAMTPALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMK 339


>gi|24308384 paraneoplastic antigen like 5 [Homo sapiens]
          Length = 448

 Score =  301 bits (772), Expect = 4e-82
 Identities = 163/348 (46%), Positives = 230/348 (66%), Gaps = 14/348 (4%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L LLEDWC+GMDM+PRKALLI GI   CS  EI++ ++AGL PL  YR+LGRMFRR++
Sbjct: 1   MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           N K   + L    ++  +P  IPGKGG W V+ KP +PD+ FLSRLN FL  EG ++ ++
Sbjct: 61  NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 120

Query: 121 SRALG---HENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPG 177
           +RALG       SLD E  ++P++ +P        L+P  + + Y+KL+VFSG  SP PG
Sbjct: 121 ARALGCCSLPAESLDAE--VMPQVRSP-------PLEPPKESMWYRKLKVFSGTASPSPG 171

Query: 178 EEEFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQAL 237
           EE F  W+   T+++  WQV +VEKRRRLLESLRGPAL ++RVL+ NN  ITV++CL AL
Sbjct: 172 EETFEDWLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDAL 231

Query: 238 EEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQ 297
           +++FG  ++ R  Q ++L T  K  EK+S ++LRLEPLLQK V +  +   + +  RL  
Sbjct: 232 KQIFGDKEDFRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKH 291

Query: 298 VIAG-AVHKTIRRELN-LPEDGPAPGFLQLLVLIKDYEAAEEEEALLQ 343
           ++A  A+   +R +L  L + G  P FL+L+ LI+D E  E  EA+++
Sbjct: 292 LLARVAMTPALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMK 339


>gi|142976816 paraneoplastic cancer-testis-brain antigen [Homo
           sapiens]
          Length = 463

 Score =  296 bits (759), Expect = 1e-80
 Identities = 162/351 (46%), Positives = 222/351 (63%), Gaps = 5/351 (1%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L LL+DWCRG  +N R+ +LI GI + C   E EE LQ     LG YR++GRMFRR+E
Sbjct: 1   MPLTLLQDWCRGEHLNTRRCMLILGIPEDCGEDEFEETLQEACRHLGRYRVIGRMFRREE 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           N +  L+ L  +  +AL+P+EIPGKGG W VI KP + D  FL+RLN FL  E  TV ++
Sbjct: 61  NAQAILLELAQDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRTVSDM 120

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQAL-EALQPALQCLKYKKLRVFSGRESPEPGEE 179
           +R LG +     P   + PE W    AQ L  A+QP L+ + Y++LRVFSG     PG  
Sbjct: 121 NRVLGSDTNCSAPRVTISPEFWT--WAQTLGAAVQPLLEQMLYRELRVFSGNTISIPGAL 178

Query: 180 EFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEE 239
            F  W+ HTT+M++ WQVP+ EKRRRL+E LRGPAL V+  L+ +N  ITV+ECL AL++
Sbjct: 179 AFDAWLEHTTEMLQMWQVPEGEKRRRLMECLRGPALQVVSGLRASNASITVEECLAALQQ 238

Query: 240 VFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVI 299
           VFG  ++ +  QVK    YQ+  EK+S++VLRLEPLLQ+ V+   + R  VNQ RL +V+
Sbjct: 239 VFGPVESHKIAQVKLCKAYQEAGEKVSSFVLRLEPLLQRAVENNVVSRRNVNQTRLKRVL 298

Query: 300 AGA-VHKTIRRELNL-PEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEG 348
           +GA +   +R +L L  +    PGFL L+ L+++ E  E      +  LEG
Sbjct: 299 SGATLPDKLRDKLKLMKQRRKPPGFLALVKLLREEEEWEATLGPDRESLEG 349


>gi|239746974 PREDICTED: hypothetical protein XP_002343900 [Homo
           sapiens]
          Length = 399

 Score =  251 bits (641), Expect = 7e-67
 Identities = 142/344 (41%), Positives = 209/344 (60%), Gaps = 23/344 (6%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M + +L+DWCR M +N R+ LLI GI + C  AE +E+L+A L P+G + +LG++FR ++
Sbjct: 1   MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKVFREED 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTF--LSRLNEFLAGEGMTVG 118
           N   ALV L  E ++ALVP+EIPG GG W V+F P      F  L R+  F   EG  V 
Sbjct: 61  NATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVE 120

Query: 119 ELSRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGE 178
            ++ ALG          G+    W   + Q   A+QP ++ ++Y+ L VFSGR+ P PGE
Sbjct: 121 SVAGALG---------VGLRRVCWLRSIGQ---AVQPWVEAVRYQSLGVFSGRDQPAPGE 168

Query: 179 EEFGRWMFHTTQMIKAWQ-VPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQAL 237
           E F  W+ HTT+M+  WQ V + E+RRRLLE LRG AL ++  L   NP  T  +CL AL
Sbjct: 169 ESFEVWLDHTTEMLHVWQGVSERERRRRLLEGLRGTALQLVHALLAENPARTAQDCLAAL 228

Query: 238 EEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQ 297
            +VFG  ++   ++VK LT  Q+  E+LSA+VLRLE LLQK +++ A+ R + ++ RL Q
Sbjct: 229 AQVFGDNESQATIRVKCLTAQQQSGERLSAFVLRLEVLLQKAMEKEALARASADRVRLRQ 288

Query: 298 VIAGA-----VHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAE 336
           ++  A     + + +R+   L   G +P FL++L L+++ EA E
Sbjct: 289 MLTRAHLTEPLDEALRK---LRMAGRSPSFLEMLGLVRESEAWE 329


>gi|187607308 paraneoplastic antigen like 6A [Homo sapiens]
          Length = 399

 Score =  251 bits (641), Expect = 7e-67
 Identities = 142/344 (41%), Positives = 209/344 (60%), Gaps = 23/344 (6%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M + +L+DWCR M +N R+ LLI GI + C  AE +E+L+A L P+G + +LG++FR ++
Sbjct: 1   MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKVFREED 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTF--LSRLNEFLAGEGMTVG 118
           N   ALV L  E ++ALVP+EIPG GG W V+F P      F  L R+  F   EG  V 
Sbjct: 61  NATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVE 120

Query: 119 ELSRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGE 178
            ++ ALG          G+    W   + Q   A+QP ++ ++Y+ L VFSGR+ P PGE
Sbjct: 121 SVAGALG---------VGLRRVCWLRSIGQ---AVQPWVEAVRYQSLGVFSGRDQPAPGE 168

Query: 179 EEFGRWMFHTTQMIKAWQ-VPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQAL 237
           E F  W+ HTT+M+  WQ V + E+RRRLLE LRG AL ++  L   NP  T  +CL AL
Sbjct: 169 ESFEVWLDHTTEMLHVWQGVSERERRRRLLEGLRGTALQLVHALLAENPARTAQDCLAAL 228

Query: 238 EEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQ 297
            +VFG  ++   ++VK LT  Q+  E+LSA+VLRLE LLQK +++ A+ R + ++ RL Q
Sbjct: 229 AQVFGDNESQATIRVKCLTAQQQSGERLSAFVLRLEVLLQKAMEKEALARASADRVRLRQ 288

Query: 298 VIAGA-----VHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAE 336
           ++  A     + + +R+   L   G +P FL++L L+++ EA E
Sbjct: 289 MLTRAHLTEPLDEALRK---LRMAGRSPSFLEMLGLVRESEAWE 329


>gi|239746972 PREDICTED: hypothetical protein XP_002343899 [Homo
           sapiens]
          Length = 399

 Score =  247 bits (630), Expect = 1e-65
 Identities = 141/344 (40%), Positives = 207/344 (60%), Gaps = 23/344 (6%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M + +L+DWCR M +N R+ LLI GI + C  AE +E+L+A L P+G + +LG+ FR ++
Sbjct: 1   MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKAFREED 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTF--LSRLNEFLAGEGMTVG 118
           N   ALV L  E ++ALVP+EIPG GG W V+F P      F  L R+  F   EG  V 
Sbjct: 61  NATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVE 120

Query: 119 ELSRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGE 178
            ++ ALG          G+    W   + Q   A+QP ++ ++ + L VFSGR+ P PGE
Sbjct: 121 SVAGALG---------VGLRRVCWLRSIGQ---AVQPWVEAVRCQSLGVFSGRDQPAPGE 168

Query: 179 EEFGRWMFHTTQMIKAWQ-VPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQAL 237
           E F  W+ HTT+M+  WQ V + E+RRRLLE LRG AL ++  L   NP  T  +CL AL
Sbjct: 169 ESFEVWLDHTTEMLHVWQGVSERERRRRLLEGLRGTALQLVHALLAENPARTAQDCLAAL 228

Query: 238 EEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQ 297
            +VFG  ++   ++VK LT  Q+  E+LSA+VLRLE LLQK +++ A+ R + ++ RL Q
Sbjct: 229 AQVFGDNESQATIRVKCLTAQQQSGERLSAFVLRLEVLLQKAMEKEALARASADRVRLRQ 288

Query: 298 VIAGA-----VHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAE 336
           ++  A     + + +R+   L   G +P FL++L L+++ EA E
Sbjct: 289 MLTRAHLTEPLDEALRK---LRMAGRSPSFLEMLGLVRESEAWE 329


>gi|239746970 PREDICTED: hypothetical protein XP_002343898 [Homo
           sapiens]
          Length = 399

 Score =  247 bits (630), Expect = 1e-65
 Identities = 141/344 (40%), Positives = 207/344 (60%), Gaps = 23/344 (6%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M + +L+DWCR M +N R+ LLI GI + C  AE +E+L+A L P+G + +LG+ FR ++
Sbjct: 1   MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKAFREED 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTF--LSRLNEFLAGEGMTVG 118
           N   ALV L  E ++ALVP+EIPG GG W V+F P      F  L R+  F   EG  V 
Sbjct: 61  NATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVE 120

Query: 119 ELSRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGE 178
            ++ ALG          G+    W   + Q   A+QP ++ ++ + L VFSGR+ P PGE
Sbjct: 121 SVAGALG---------VGLRRVCWLRSIGQ---AVQPWVEAVRCQSLGVFSGRDQPAPGE 168

Query: 179 EEFGRWMFHTTQMIKAWQ-VPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQAL 237
           E F  W+ HTT+M+  WQ V + E+RRRLLE LRG AL ++  L   NP  T  +CL AL
Sbjct: 169 ESFEVWLDHTTEMLHVWQGVSERERRRRLLEGLRGTALQLVHALLAENPARTAQDCLAAL 228

Query: 238 EEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQ 297
            +VFG  ++   ++VK LT  Q+  E+LSA+VLRLE LLQK +++ A+ R + ++ RL Q
Sbjct: 229 AQVFGDNESQATIRVKCLTAQQQSGERLSAFVLRLEVLLQKAMEKEALARASADRVRLRQ 288

Query: 298 VIAGA-----VHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAE 336
           ++  A     + + +R+   L   G +P FL++L L+++ EA E
Sbjct: 289 MLTRAHLTEPLDEALRK---LRMAGRSPSFLEMLGLVRESEAWE 329


>gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
           sapiens]
          Length = 601

 Score =  157 bits (398), Expect = 1e-38
 Identities = 111/340 (32%), Positives = 168/340 (49%), Gaps = 64/340 (18%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           + L +L+DWCR M +N  ++LLI  I   C   E +EA++A L+PLG YR+L ++FR++ 
Sbjct: 191 IALAMLQDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFRKEL 250

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
             + ALV                                        EF   EG+    +
Sbjct: 251 GARAALV----------------------------------------EF--AEGLNQSLI 268

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE 180
            R +  + G            W   +    + L+P ++ + Y++LR FSGRE P   EE 
Sbjct: 269 PRQIAGKGGP-----------WK--VISLPQTLRPLVKTMAYRELRPFSGREQPGCVEES 315

Query: 181 FGRWMFHTTQMIKAW-QVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEE 239
           F  W+     M++ W    + E+RRRLL+SL G ALD++  L   +P  +  +CL AL +
Sbjct: 316 FESWLEDAKDMLQLWCHASERERRRRLLDSLDGLALDIVSGLLEEDPDFSAQDCLTALGQ 375

Query: 240 VFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVI 299
           VF   D     ++K+LT  Q  +E L A+V+RLE LLQK V++GA+     N  RL QV+
Sbjct: 376 VFRSRDTWMTSRMKFLTCTQGPQEGLFAFVVRLEGLLQKAVEKGAVHPAMANHLRLRQVL 435

Query: 300 -----AGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEA 334
                + A+  T+RR   +  +   P FL+LL LI+D EA
Sbjct: 436 SRARPSEALQDTLRR---MQLERRPPDFLRLLRLIRDMEA 472


>gi|169216516 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
           sapiens]
          Length = 541

 Score =  157 bits (398), Expect = 1e-38
 Identities = 111/340 (32%), Positives = 168/340 (49%), Gaps = 64/340 (18%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           + L +L+DWCR M +N  ++LLI  I   C   E +EA++A L+PLG YR+L ++FR++ 
Sbjct: 131 IALAMLQDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFRKEL 190

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
             + ALV                                        EF   EG+    +
Sbjct: 191 GARAALV----------------------------------------EF--AEGLNQSLI 208

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE 180
            R +  + G            W   +    + L+P ++ + Y++LR FSGRE P   EE 
Sbjct: 209 PRQIAGKGGP-----------WK--VISLPQTLRPLVKTMAYRELRPFSGREQPGCVEES 255

Query: 181 FGRWMFHTTQMIKAW-QVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEE 239
           F  W+     M++ W    + E+RRRLL+SL G ALD++  L   +P  +  +CL AL +
Sbjct: 256 FESWLEDAKDMLQLWCHASERERRRRLLDSLDGLALDIVSGLLEEDPDFSAQDCLTALGQ 315

Query: 240 VFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVI 299
           VF   D     ++K+LT  Q  +E L A+V+RLE LLQK V++GA+     N  RL QV+
Sbjct: 316 VFRSRDTWMTSRMKFLTCTQGPQEGLFAFVVRLEGLLQKAVEKGAVHPAMANHLRLRQVL 375

Query: 300 -----AGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEA 334
                + A+  T+RR   +  +   P FL+LL LI+D EA
Sbjct: 376 SRARPSEALQDTLRR---MQLERRPPDFLRLLRLIRDMEA 412


>gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
           sapiens]
          Length = 601

 Score =  157 bits (398), Expect = 1e-38
 Identities = 111/340 (32%), Positives = 168/340 (49%), Gaps = 64/340 (18%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           + L +L+DWCR M +N  ++LLI  I   C   E +EA++A L+PLG YR+L ++FR++ 
Sbjct: 191 IALAMLQDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFRKEL 250

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
             + ALV                                        EF   EG+    +
Sbjct: 251 GARAALV----------------------------------------EF--AEGLNQSLI 268

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE 180
            R +  + G            W   +    + L+P ++ + Y++LR FSGRE P   EE 
Sbjct: 269 PRQIAGKGGP-----------WK--VISLPQTLRPLVKTMAYRELRPFSGREQPGCVEES 315

Query: 181 FGRWMFHTTQMIKAW-QVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEE 239
           F  W+     M++ W    + E+RRRLL+SL G ALD++  L   +P  +  +CL AL +
Sbjct: 316 FESWLEDAKDMLQLWCHASERERRRRLLDSLDGLALDIVSGLLEEDPDFSAQDCLTALGQ 375

Query: 240 VFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVI 299
           VF   D     ++K+LT  Q  +E L A+V+RLE LLQK V++GA+     N  RL QV+
Sbjct: 376 VFRSRDTWMTSRMKFLTCTQGPQEGLFAFVVRLEGLLQKAVEKGAVHPAMANHLRLRQVL 435

Query: 300 -----AGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEA 334
                + A+  T+RR   +  +   P FL+LL LI+D EA
Sbjct: 436 SRARPSEALQDTLRR---MQLERRPPDFLRLLRLIRDMEA 472


>gi|169216507 PREDICTED: similar to hCG1645335 [Homo sapiens]
          Length = 409

 Score =  151 bits (381), Expect = 1e-36
 Identities = 116/340 (34%), Positives = 161/340 (47%), Gaps = 67/340 (19%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L +L DWCR M  N  ++LLI GI   C   E +EA++A L+PLG YR+L + FR++ 
Sbjct: 1   MALAMLRDWCRWMGANAERSLLILGIPDDCKEHEFQEAVRAALSPLGRYRVLTKHFRKEL 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
             K A                                     L    E+L          
Sbjct: 61  GAKAA-------------------------------------LVEFAEYL---------- 73

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE 180
                  N SL P Q  IP    P     L   QP L+   Y++LR FS RE P   EE 
Sbjct: 74  -------NRSLIPHQ--IPGNGGPWKVIFLP--QPVLENRAYRELRPFSRREQPGCEEES 122

Query: 181 FGRWMFHTTQMIKAW-QVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEE 239
           F  W+ H   M++ W    + EK+R LLESL GPAL+V+  L   +  ++  +CL AL +
Sbjct: 123 FESWVEHAKDMLQLWCHASEREKKRWLLESLGGPALEVVSGLLEEDTNLSALDCLAALGQ 182

Query: 240 VFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVI 299
           VF   D     ++K+LT  Q  +E L A+V+RLE LLQ+ V++GA+     N  RL QV+
Sbjct: 183 VFRNQDTRMTSRLKFLTCTQGPQEGLFAFVVRLEGLLQRAVEKGAVCPALANYLRLQQVL 242

Query: 300 -----AGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEA 334
                + A+  T+R    +  +   PGFL LL LI++ EA
Sbjct: 243 SWARPSEALQDTLR---GMQLEKRPPGFLGLLRLIREMEA 279


>gi|169216732 PREDICTED: similar to hCG1645335 [Homo sapiens]
          Length = 409

 Score =  151 bits (381), Expect = 1e-36
 Identities = 116/340 (34%), Positives = 161/340 (47%), Gaps = 67/340 (19%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L +L DWCR M  N  ++LLI GI   C   E +EA++A L+PLG YR+L + FR++ 
Sbjct: 1   MALAMLRDWCRWMGANAERSLLILGIPDDCKEHEFQEAVRAALSPLGRYRVLTKHFRKEL 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
             K A                                     L    E+L          
Sbjct: 61  GAKAA-------------------------------------LVEFAEYL---------- 73

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEE 180
                  N SL P Q  IP    P     L   QP L+   Y++LR FS RE P   EE 
Sbjct: 74  -------NRSLIPHQ--IPGNGGPWKVIFLP--QPVLENRAYRELRPFSRREQPGCEEES 122

Query: 181 FGRWMFHTTQMIKAW-QVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEE 239
           F  W+ H   M++ W    + EK+R LLESL GPAL+V+  L   +  ++  +CL AL +
Sbjct: 123 FESWVEHAKDMLQLWCHASEREKKRWLLESLGGPALEVVSGLLEEDTNLSALDCLAALGQ 182

Query: 240 VFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVI 299
           VF   D     ++K+LT  Q  +E L A+V+RLE LLQ+ V++GA+     N  RL QV+
Sbjct: 183 VFRNQDTRMTSRLKFLTCTQGPQEGLFAFVVRLEGLLQRAVEKGAVCPALANYLRLQQVL 242

Query: 300 -----AGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEA 334
                + A+  T+R    +  +   PGFL LL LI++ EA
Sbjct: 243 SWARPSEALQDTLR---GMQLEKRPPGFLGLLRLIREMEA 279


>gi|156766054 PNMA-like 1 isoform b [Homo sapiens]
          Length = 378

 Score =  141 bits (356), Expect = 8e-34
 Identities = 75/194 (38%), Positives = 110/194 (56%), Gaps = 2/194 (1%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M + LLEDWCRGM+++  ++LL+ GI + C  AEIEE L   L+PLG YR+L ++F R+E
Sbjct: 5   MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           N K AL+ +    + + +P+E PG+GG+WRV+ + P  D  FL  LNEFL  EG T  ++
Sbjct: 65  NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGE-E 179
            R L   + +L   Q   PE WA  L   L A+   + C+   ++R      + E  E E
Sbjct: 125 VRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMD-AEIRSREEARAQEAAEFE 183

Query: 180 EFGRWMFHTTQMIK 193
           E   W     + +K
Sbjct: 184 EMAAWALAAGRKVK 197


>gi|39780597 PNMA-like 1 isoform a [Homo sapiens]
          Length = 439

 Score =  141 bits (356), Expect = 8e-34
 Identities = 75/194 (38%), Positives = 110/194 (56%), Gaps = 2/194 (1%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M + LLEDWCRGM+++  ++LL+ GI + C  AEIEE L   L+PLG YR+L ++F R+E
Sbjct: 5   MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
           N K AL+ +    + + +P+E PG+GG+WRV+ + P  D  FL  LNEFL  EG T  ++
Sbjct: 65  NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124

Query: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGE-E 179
            R L   + +L   Q   PE WA  L   L A+   + C+   ++R      + E  E E
Sbjct: 125 VRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMD-AEIRSREEARAQEAAEFE 183

Query: 180 EFGRWMFHTTQMIK 193
           E   W     + +K
Sbjct: 184 EMAAWALAAGRKVK 197


>gi|28557790 zinc finger, CCHC domain containing 12 [Homo sapiens]
          Length = 402

 Score =  117 bits (292), Expect = 2e-26
 Identities = 66/200 (33%), Positives = 112/200 (56%), Gaps = 8/200 (4%)

Query: 142 WAPMLAQAL-EALQPALQCLKYKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQVPDV 200
           WA  + ++L  +L P +  +  + +++FSGR  P  GEE F  W+     ++  W + + 
Sbjct: 21  WAHSMLRSLGRSLGPIMASMADRNMKLFSGRVVPAQGEETFENWLTQVNGVLPDWNMSEE 80

Query: 201 EKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYLTTYQK 260
           EK +RL+++LRGPA +V+RVL+  NP ++V + L+A++ VFG +++      K+  T Q 
Sbjct: 81  EKLKRLMKTLRGPAREVMRVLQATNPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQA 140

Query: 261 DEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQ-VIAGAVHKTIRRELN------L 313
             EK S YV+RLE  LQ  +Q G I     N+ RL Q ++ G + + +R  L        
Sbjct: 141 QGEKASLYVIRLEVQLQNAIQAGIIAEKDANRTRLQQLLLGGELSRDLRLRLKDFLRMYA 200

Query: 314 PEDGPAPGFLQLLVLIKDYE 333
            E    P FL+L+ ++++ E
Sbjct: 201 NEQERLPNFLELIRMVREEE 220


>gi|221136806 zinc finger, CCHC domain containing 18 [Homo sapiens]
          Length = 403

 Score =  116 bits (290), Expect = 3e-26
 Identities = 65/200 (32%), Positives = 115/200 (57%), Gaps = 8/200 (4%)

Query: 142 WAPMLAQAL-EALQPALQCLKYKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQVPDV 200
           WA  + ++L  +L P +  +  + +++FSGR  P  G+E F  W+    +++  W + + 
Sbjct: 21  WAHSMLRSLGRSLCPLVVKMAERNMKLFSGRVVPAQGKETFENWLIQVNEVLPDWSMSEE 80

Query: 201 EKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYLTTYQK 260
           EK +RL+++LRGPA +V+R+L+  NP ++V + L+A++ VFG +++      K+  T Q 
Sbjct: 81  EKLKRLMKTLRGPAREVMRLLQAANPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQA 140

Query: 261 DEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVIAGA-VHKTIRRELN------L 313
             EK S YV+RLE  LQ  +Q G +     NQ RL Q++ GA +++ +R  L        
Sbjct: 141 QGEKASLYVIRLEVQLQNAIQAGILAEKDANQTRLQQLLLGAELNRDLRFRLKHLLRMYA 200

Query: 314 PEDGPAPGFLQLLVLIKDYE 333
            +    P FL+L+ +I++ E
Sbjct: 201 NKQERLPNFLELIKMIREEE 220


>gi|146219841 PNMA-like 2 [Homo sapiens]
          Length = 635

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 45/116 (38%), Positives = 68/116 (58%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M + LL+DWCR +D++  +ALL+ GI +    A++E  LQ  L PLG +RL       +E
Sbjct: 1   MAMSLLQDWCRSLDVDAHRALLVTGIPEGLEQADVEAVLQPTLLPLGTFRLRHMKALMNE 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMT 116
             + ALV    + +HA +P+EIPGK G+WRV++K    D   L ++   L  +G T
Sbjct: 61  KAQAALVEFVEDVNHAAIPREIPGKDGVWRVLWKDRAQDTRVLRQMRRLLLDDGPT 116


>gi|169216514 PREDICTED: similar to paraneoplastic antigen MA2 [Homo
           sapiens]
          Length = 340

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 48/120 (40%), Positives = 70/120 (58%), Gaps = 1/120 (0%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L +L DWCR M +N  ++LLI  I   C   E +EA++A L+PLG YR+L ++FR++ 
Sbjct: 1   MALAMLRDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFRKEL 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEF-LAGEGMTVGE 119
             + ALV      + +L+P++I GKGG W+VI  P   D  F    +E   AGE    G+
Sbjct: 61  GARAALVEFAEGLNQSLIPRQIAGKGGPWKVISLPQALDAEFQDIPSEAGAAGEEEEAGD 120



 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 55/159 (34%), Positives = 77/159 (48%), Gaps = 16/159 (10%)

Query: 111 AGEGMTVGELSRALGHENGSLDPEQGMIPEMWAPMLAQALE-----ALQPALQCLKYKKL 165
           AGE   VGE   A+G    +   E G + E     + +A        LQ  L+   Y++L
Sbjct: 185 AGEAEAVGEAG-AVGEAGAA--GEAGAVGEARGTNVTRAWVQPRRCTLQAVLENRAYQEL 241

Query: 166 RVFSGRESPEPGEEEFGRWMFHTTQMIKAW-QVPDVEKRRRLLESLRGPALDVIRVLKIN 224
           R FSGRE P   EE F  WM H   M++ W    + E++R LLESL GPALDV+  L   
Sbjct: 242 RPFSGREQPGCEEESFESWMEHAKDMLQLWYHASERERKRWLLESLGGPALDVVSGLLEE 301

Query: 225 NPLITVDECLQALE-------EVFGVTDNPRELQVKYLT 256
           +P +   +C   L+       + FG  D     ++K+LT
Sbjct: 302 DPNLAALDCQVLLDCWAAVLGQAFGNRDPRMTSRLKFLT 340


>gi|169216749 PREDICTED: similar to Putative paraneoplastic
           antigen-like protein 6B-like protein [Homo sapiens]
          Length = 340

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 48/120 (40%), Positives = 70/120 (58%), Gaps = 1/120 (0%)

Query: 1   MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
           M L +L DWCR M +N  ++LLI  I   C   E +EA++A L+PLG YR+L ++FR++ 
Sbjct: 1   MALAMLRDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFRKEL 60

Query: 61  NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEF-LAGEGMTVGE 119
             + ALV      + +L+P++I GKGG W+VI  P   D  F    +E   AGE    G+
Sbjct: 61  GARAALVEFAEGLNQSLIPRQIAGKGGPWKVISLPQALDAEFQDIPSEAGAAGEEEEAGD 120



 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 55/159 (34%), Positives = 77/159 (48%), Gaps = 16/159 (10%)

Query: 111 AGEGMTVGELSRALGHENGSLDPEQGMIPEMWAPMLAQALE-----ALQPALQCLKYKKL 165
           AGE   VGE   A+G    +   E G + E     + +A        LQ  L+   Y++L
Sbjct: 185 AGEAEAVGEAG-AVGEAGAA--GEAGAVGEARGTNVTRAWVQPRRCTLQAVLENRAYQEL 241

Query: 166 RVFSGRESPEPGEEEFGRWMFHTTQMIKAW-QVPDVEKRRRLLESLRGPALDVIRVLKIN 224
           R FSGRE P   EE F  WM H   M++ W    + E++R LLESL GPALDV+  L   
Sbjct: 242 RPFSGREQPGCKEESFESWMEHAKDMLQLWYHASERERKRWLLESLGGPALDVVSGLLEE 301

Query: 225 NPLITVDECLQALE-------EVFGVTDNPRELQVKYLT 256
           +P +   +C   L+       + FG  D     ++K+LT
Sbjct: 302 DPNLAALDCQVLLDCWAAVLGQAFGNRDPRMTSRLKFLT 340


>gi|199559779 coiled-coil domain containing 8 [Homo sapiens]
          Length = 538

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 33/53 (62%)

Query: 72  ETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGELSRAL 124
           +  + L+P+E+   GG+WRVI KP   +  F  RL +FL  EG T+ +++R +
Sbjct: 7   DVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIM 59


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 10/78 (12%)

Query: 138 IPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEE-----EFGRWMFHTTQMI 192
           +PEM  P L + L  LQ     L Y  L +     + +PG+E     E G+W++H + + 
Sbjct: 94  VPEMVRPTLERTLRVLQ-----LDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLC 148

Query: 193 KAWQVPDVEKRRRLLESL 210
             W+  +  K   L++SL
Sbjct: 149 ATWEAMEACKDAGLVKSL 166


>gi|218505835 membrane-associated guanylate kinase-related  3
           isoform 1 [Homo sapiens]
          Length = 1481

 Score = 33.5 bits (75), Expect = 0.29
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 8/72 (11%)

Query: 281 QRGAIERDAVNQARLDQVIAGAVH-KTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEE 339
           Q+G+I+       +L QVI   ++ +TI      P DG  PG     + ++ ++A EE  
Sbjct: 122 QKGSIDH------KLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESG 175

Query: 340 ALLQA-ILEGNF 350
           ALL++   +GNF
Sbjct: 176 ALLESGTYDGNF 187


>gi|155969695 membrane-associated guanylate kinase-related  3
           isoform 2 [Homo sapiens]
          Length = 1125

 Score = 33.5 bits (75), Expect = 0.29
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 8/72 (11%)

Query: 281 QRGAIERDAVNQARLDQVIAGAVH-KTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEE 339
           Q+G+I+       +L QVI   ++ +TI      P DG  PG     + ++ ++A EE  
Sbjct: 122 QKGSIDH------KLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESG 175

Query: 340 ALLQA-ILEGNF 350
           ALL++   +GNF
Sbjct: 176 ALLESGTYDGNF 187


>gi|221554526 coiled-coil domain containing 42B [Homo sapiens]
          Length = 308

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 10/101 (9%)

Query: 217 VIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLL 276
           V+R+L+    L+  D+ LQA +EVF        L+ ++    QK+ E L    +R +  L
Sbjct: 32  VLRLLEKRQELVDADQALQAQKEVF--RTKTAALKQRWEQLEQKERE-LKGSFIRFDKFL 88

Query: 277 Q-------KLVQRGAIERDAVNQARLDQVIAGAVHKTIRRE 310
           Q       + ++R A ER    +  ++ +      + +RRE
Sbjct: 89  QDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRRE 129


>gi|223555921 hepatocellular carcinoma related protein 1 isoform 2
           [Homo sapiens]
          Length = 372

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 32/165 (19%)

Query: 213 PALDVIRVLKINNPLITVDECLQALEEVFG--VTDNP------RELQVKYLTTYQKDEEK 264
           P+  V+  L +  P+ TVD  +   +  FG  + D P       EL V  LT   + EE 
Sbjct: 169 PSFGVLSNLPL--PIPTVDASIPTSQNGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEV 226

Query: 265 LSAYVLRLEPLLQKLVQRGAIER----------------DAVNQARLDQV-----IAGAV 303
           L    L L  L Q +  +  + +                +A  Q  LD+      +    
Sbjct: 227 LLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYELLTQMKSTF 286

Query: 304 HKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEG 348
            K ++R+  L E   A   LQ  + +  +EA EE + + +  LEG
Sbjct: 287 EKKMQRQHELSESCSASA-LQARLKVAAHEAEEESDNIAEDFLEG 330


>gi|223555919 hepatocellular carcinoma related protein 1 isoform 1
           [Homo sapiens]
          Length = 397

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 32/165 (19%)

Query: 213 PALDVIRVLKINNPLITVDECLQALEEVFG--VTDNP------RELQVKYLTTYQKDEEK 264
           P+  V+  L +  P+ TVD  +   +  FG  + D P       EL V  LT   + EE 
Sbjct: 194 PSFGVLSNLPL--PIPTVDASIPTSQNGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEV 251

Query: 265 LSAYVLRLEPLLQKLVQRGAIER----------------DAVNQARLDQV-----IAGAV 303
           L    L L  L Q +  +  + +                +A  Q  LD+      +    
Sbjct: 252 LLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYELLTQMKSTF 311

Query: 304 HKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEG 348
            K ++R+  L E   A   LQ  + +  +EA EE + + +  LEG
Sbjct: 312 EKKMQRQHELSESCSASA-LQARLKVAAHEAEEESDNIAEDFLEG 355


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,018,017
Number of Sequences: 37866
Number of extensions: 630003
Number of successful extensions: 1561
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1495
Number of HSP's gapped (non-prelim): 48
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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