BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|19923559 EMSY protein [Homo sapiens] (1322 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|19923559 EMSY protein [Homo sapiens] 2536 0.0 gi|91982772 mucin 17 [Homo sapiens] 108 3e-23 gi|83367077 mucin 16 [Homo sapiens] 94 7e-19 gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 91 1e-17 gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 87 1e-16 gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap... 84 7e-16 gi|116284392 mucin 2 precursor [Homo sapiens] 84 1e-15 gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 81 6e-15 gi|161019170 mucin 5AC [Homo sapiens] 81 8e-15 gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 80 1e-14 gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14 gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14 gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14 gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14 gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14 gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14 gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14 gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14 gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 79 3e-14 gi|167736355 mucin 4 isoform a [Homo sapiens] 78 5e-14 gi|98986457 host cell factor 1 [Homo sapiens] 77 1e-13 gi|151301154 mucin 6, gastric [Homo sapiens] 77 1e-13 gi|56549696 E1A binding protein p400 [Homo sapiens] 75 3e-13 gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti... 75 5e-13 gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 74 7e-13 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 74 1e-12 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 74 1e-12 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 70 1e-11 gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 70 1e-11 gi|38788274 bromodomain PHD finger transcription factor isoform ... 70 1e-11 >gi|19923559 EMSY protein [Homo sapiens] Length = 1322 Score = 2536 bits (6574), Expect = 0.0 Identities = 1322/1322 (100%), Positives = 1322/1322 (100%) Query: 1 MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSIST 60 MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSIST Sbjct: 1 MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSIST 60 Query: 61 ERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVA 120 ERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVA Sbjct: 61 ERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVA 120 Query: 121 NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV 180 NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV Sbjct: 121 NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV 180 Query: 181 LPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPK 240 LPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPK Sbjct: 181 LPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPK 240 Query: 241 MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300 MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY Sbjct: 241 MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300 Query: 301 AAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP 360 AAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP Sbjct: 301 AAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP 360 Query: 361 SVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ 420 SVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ Sbjct: 361 SVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ 420 Query: 421 QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS 480 QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS Sbjct: 421 QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS 480 Query: 481 SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII 540 SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII Sbjct: 481 SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII 540 Query: 541 TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV 600 TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV Sbjct: 541 TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV 600 Query: 601 TTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQ 660 TTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQ Sbjct: 601 TTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQ 660 Query: 661 QGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSS 720 QGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSS Sbjct: 661 QGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSS 720 Query: 721 SSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL 780 SSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL Sbjct: 721 SSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL 780 Query: 781 ELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTER 840 ELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTER Sbjct: 781 ELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTER 840 Query: 841 TDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHI 900 TDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHI Sbjct: 841 TDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHI 900 Query: 901 MQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE 960 MQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE Sbjct: 901 MQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE 960 Query: 961 QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQH 1020 QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQH Sbjct: 961 QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQH 1020 Query: 1021 TQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 TQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSL Sbjct: 1021 TQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA Sbjct: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS Sbjct: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 Query: 1201 TPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAI 1260 TPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAI Sbjct: 1201 TPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAI 1260 Query: 1261 PQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAE 1320 PQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAE Sbjct: 1261 PQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAE 1320 Query: 1321 RS 1322 RS Sbjct: 1321 RS 1322 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 108 bits (271), Expect = 3e-23 Identities = 256/1279 (20%), Positives = 431/1279 (33%), Gaps = 141/1279 (11%) Query: 52 LSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIE----GRRLVPLMPRLV 107 LS L +S+E TT S P ++ SI+ R PL V Sbjct: 1992 LSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPV 2051 Query: 108 PQTAF---------TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTST--TSTPTST 156 T T ++ AS AE S + S S TS P ST Sbjct: 2052 STTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLST 2111 Query: 157 PVPSGSIATVKSPRPASPASNVVVLP--SGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSP 214 + A+ S P S V+ S S + + S R+ T+ S+ Sbjct: 2112 TPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTT 2171 Query: 215 VVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVK--ITFTKPSTQTTN 272 VV + + PV+ S + + + + P +P + FT T Sbjct: 2172 VVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMP 2231 Query: 273 TTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK---LVPTSVIASTTQKPPVVITASQSS 329 T + ++ +P T P S + T +PTS ++ T P+ + Sbjct: 2232 VVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTT--PLTSIPVSHT 2289 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAI-KMASTRLPSPKS 388 LV+NS + S+TP NT T+ +S+P + STS+ TR+P + Sbjct: 2290 LVANSEVSTLSTTPVD-SNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTT 2348 Query: 389 LVSA-PTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPT 447 +V++ T L+ P T Q + S G P Sbjct: 2349 MVASFETSTLSTTPADTS---------TPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPL 2399 Query: 448 IQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV---TTPT 504 + S + +++ + P + + TS+ + ++ G + T TTP Sbjct: 2400 TSVPV-STMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 2458 Query: 505 GTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT--------VVPKSLATLGGKIIS 556 + T P VS G ++ TP + TTS + VVP S A+ G +++ Sbjct: 2459 ASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLT 2518 Query: 557 SNIVSGT------TTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEK 610 S VS T + ++T P+ S V+ + + T+ +G + T + G Sbjct: 2519 SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEG----TSMPTSTYSEGST 2574 Query: 611 TIQTVPTGAKP-----AILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ---G 662 ++++P KP A +T P+ I S+ AK I + Sbjct: 2575 PLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTS 2634 Query: 663 KTQVLIKPKPV-TFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSS 721 T +L+ PV + +A+ +S T + T TL S G SS + T + Sbjct: 2635 LTSILVSTMPVASSEASTLS--TTPVDTRTLVTTS----TGTSS---------SPTTAEG 2679 Query: 722 SSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLE 781 SS +S + S P+ +++ S + + T+P V++ +++++S A Sbjct: 2680 SSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTA--- 2736 Query: 782 LQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHS--------PESPSIAVVESELVA 833 + T+++ S P + +P+ ++ S P + S S A Sbjct: 2737 -EGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTA 2795 Query: 834 EYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASS 893 E +T+ T +E + PL + S TL + T TS S P ++ Sbjct: 2796 E-VTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854 Query: 894 PGAITHIMQQALSSH--TAFTKHSEELGTEEG---EVEEMDTLDPQTGLFYRSALTQSQS 948 G + I + S T+ + + + E +DT P T S+ + Sbjct: 2855 EGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE 2914 Query: 949 AKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLT--- 1005 +S P T L + + L + + P T Sbjct: 2915 GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEG 2974 Query: 1006 ---PLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAP 1062 P+ + P + M + TL P T V P + Sbjct: 2975 TSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGT 3034 Query: 1063 NQP-KIYVQPQTPQSQMSL--------PASSEKQTASQVEQPIITQGS-SVTKITFEGRQ 1112 P + TP + + + AS+ T P++T S + EG Sbjct: 3035 GIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTS 3094 Query: 1113 PPTVTKITGG---SSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVD 1169 P T G + VP T+PVTS S I T V + T+ E Sbjct: 3095 MPISTYSEGSTPLTGVPVSTTPVTS-SAISTLSTTPVD-------TSTPVTTSTEAHSSP 3146 Query: 1170 PPKKALATSMLTGEAGSLPSTHMVVAGM---------ANSTPQQQK-----CRESCSSPS 1215 + + T GS P T+M V+ M ++TP E+ SS + Sbjct: 3147 TTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTT 3206 Query: 1216 TVGSSLTTRKIDPPAVPAT 1234 G+S+ T P T Sbjct: 3207 AEGTSIPTSTPSEGMTPLT 3225 Score = 108 bits (269), Expect = 4e-23 Identities = 229/1138 (20%), Positives = 414/1138 (36%), Gaps = 133/1138 (11%) Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204 S STT TS PV + S T SP A S + PS + + S+ S P Sbjct: 2592 STLSTTPVDTSIPVTT-STETSSSPTTAKDTSMPISTPSEVSTSLTSILVST---MPVAS 2647 Query: 205 RRTNSSSSSPVVLKEV----------PKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP 254 ++ S++PV + + P S + P S ++NI+ ++ +L Sbjct: 2648 SEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNIL--VSTTLLA 2705 Query: 255 HMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS 314 + ++ T T T TT+ + T+ T + I + S +T ++ +++ + Sbjct: 2706 NSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM-RISTPSDGSTPLTSILVSTLPVA 2764 Query: 315 TTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS------------- 361 +++ V TA +S+ +S+ +SSS P T VT++ +STPS Sbjct: 2765 SSEASTVSTTAVDTSIPVTTSTEASSS-----PTTAEVTSMPTSTPSETSTPLTSMPVNH 2819 Query: 362 -VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ 420 V S+ A +ST+ + ++ S K+ S T P L + T Sbjct: 2820 TPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST- 2878 Query: 421 QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKI-LPKPVTATLPT 479 +PV+ + S P + E T + I P V+ L + Sbjct: 2879 ------TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTS 2932 Query: 480 SSNSPIMVVSSNGAIMTTKLV--TTPTGTQA-TYTRPTVSPSIGRMAATPG-AATYVKTT 535 S + V S + ++T V TP T A + PT + +TPG T + + Sbjct: 2933 ILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSM 2992 Query: 536 SGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLP 595 S S + V +TL ++ T+T+ ++ P T++ I + + T + +P Sbjct: 2993 SVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIP 3052 Query: 596 GKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTK 655 V TT + T+ T P + ++T+T + + P T P + Sbjct: 3053 ---VSTTPVAIPEASTLSTTPVDSNSPVVTSTE-----VSSSPTPAEGTSMPISTYSE-- 3102 Query: 656 IVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQN 715 G T V + PVT A + + T + T T + E + Sbjct: 3103 ---GSTPLTGVPVSTTPVTSSA-ISTLSTTPVDTST-------------PVTTSTEAHSS 3145 Query: 716 YTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATST 775 T S +S +S S+ S P+ ++ S S + + +P V++ +++ +ST Sbjct: 3146 PTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSST 3205 Query: 776 IKALLELQQTTVKE---KLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELV 832 + +T E L S P T S A + T ++P + S Sbjct: 3206 TAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS--------- 3256 Query: 833 AEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPAS 892 E ++ T EGT + S P + S P ++ V+ + A+ + + + PA Sbjct: 3257 TEASSSPPTAEGTSMP-------TSTPSEGSTPLTSM--PVSTTTVASSETSTLSTTPAD 3307 Query: 893 SPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQ 952 + +T Q + S A EG P T + + + T S++ Sbjct: 3308 TSTPVTTYSQASSSPPIADGTSMPTSTYSEGST-------PLTNMSF--STTPVVSSEAS 3358 Query: 953 KLSQPPLE-QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQ 1011 LS P++ T + T + + + + + + + Sbjct: 3359 TLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNT 3418 Query: 1012 AQPKP---------DVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAP 1062 P + + P +A+ LPT T + ++ + TT +A Sbjct: 3419 LSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVAS--SEAS 3476 Query: 1063 NQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGG 1122 V TP + S P +S TA P T G T +T P + T + Sbjct: 3477 TLSTTPVDTSTPVTTSS-PTNSSPTTAEVTSMPTSTAGEGSTPLT---NMPVSTTPVASS 3532 Query: 1123 SSVPKLTSPVTSISPIQASEKTAVSD-ILKMSLMEAQIDTNVEHMIVDPPKKALATSMLT 1181 + T+PV S + + +S + + S L+++ M + + L+++ +T Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLT---TMLLSSTYVT 3589 Query: 1182 GEAGSLPSTHMV-------VAGMANSTP-QQQKCRESCSSPSTVGSSLTTRKIDPPAV 1231 S PST V + +NSTP + S+PS V + LT + +V Sbjct: 3590 SSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSV 3647 Score = 106 bits (265), Expect = 1e-22 Identities = 274/1318 (20%), Positives = 467/1318 (35%), Gaps = 180/1318 (13%) Query: 76 LTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQ------TAFTVTANAVANAAIQHNAS 129 +TT S P ++ + S MP P T+ V+ VA++ ++ Sbjct: 2605 VTTSTETSSSPTTAKDTS---------MPISTPSEVSTSLTSILVSTMPVASSEASTLST 2655 Query: 130 LPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYV 189 PV T + + T T+S+PT+ S+ T ++P +N++V ST + Sbjct: 2656 TPVDTRT-----LVTTSTGTSSSPTTAE--GSSMPTSTPGERSTPLTNILV----STTLL 2704 Query: 190 KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249 + S P T++ ++ P S I+ P GS +++I+ Sbjct: 2705 ANSEASTLSTTPVD---TSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSIL---- 2757 Query: 250 NSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPT 309 +S + + ++ ST +T T I VTTS + S S A VT + PT Sbjct: 2758 ------VSTLPVASSEASTVST-TAVDTSIPVTTSTEA-------SSSPTTAEVTSM-PT 2802 Query: 310 SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS------VV 363 S + T+ P+ + V++S +G+ S+TP V + SS+P+ V Sbjct: 2803 STPSETST--PLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVP 2860 Query: 364 MSTVAQGVST-SAIKMASTRLPSPKSLVSAPTQILAQFP----KQHQQSPKQQLYQVQQQ 418 +ST ++G + ++I +++T + S ++ + T + P + SP + Sbjct: 2861 ISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPT-----TAEG 2915 Query: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478 T ++ PS VS +PL + T+ + + T V PVT + Sbjct: 2916 TSMPISTPSEVS-------TPLTSILVSTVPVAGSEASTLSTTPVDTRT----PVTTSAE 2964 Query: 479 TSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGS 538 SS SP ++ I T TP + + T P S ++ TP + TTS Sbjct: 2965 ASS-SPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTE 3023 Query: 539 II--------TVVPKSLATLGGKIISSNIVSGTTTKI------TTIPMTSKPNVIVVQKT 584 T +P S + G ++S VS T I +T P+ S V+ + Sbjct: 3024 ASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEV 3083 Query: 585 TGKGTTIQG--------------LPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATR-- 628 + T +G L G V TT + + T+ T P + T+T Sbjct: 3084 SSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAH 3143 Query: 629 --PITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQ 686 P T + P S +P T +++ + T AT V T Sbjct: 3144 SSPTTSEGTSMPTSTPSEGSTPLTYMPVS--------TMLVVSSEDSTLSATPVDTST-P 3194 Query: 687 LVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQD 746 + T T +S AE + E T S+T + S V ++ Sbjct: 3195 VTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLT 3254 Query: 747 WSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMA 806 S A + PT + + + S ST + + TTV S D S Sbjct: 3255 TSTE--ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTS--- 3309 Query: 807 VPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAF---PLLVSHRSQ----P 859 T +S S S + + + +E + T ++F P++ S S P Sbjct: 3310 -----TPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP 3364 Query: 860 QQPSQPQRTLLQHVAQSQTATQTSVVVKSIP------ASSPGAITHIMQQALSSHTAFTK 913 S P T + TA TS+ S AS P + T ++ +++ + Sbjct: 3365 VDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPV 3424 Query: 914 HSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQ 973 S L T E T+ T L + S LS P+ ++ + Sbjct: 3425 DSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVD 3484 Query: 974 TKQKQTIH--LQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQ 1031 T T + ++ MP T E + P ++ + P+ + + Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMP---------TSTAGEGSTPLTNMPVSTTPVASSEAS 3535 Query: 1032 LPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQ 1091 TL P + V + P Q ++ + S ++ SS T+S+ Sbjct: 3536 --TLSTTPVDSNTFVTSSSQASSSPATLQVTTM-RMSTPSEGSSSLTTMLLSSTYVTSSE 3592 Query: 1092 VEQPI---ITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSD 1148 P + + + VT T P IT S P S +I P+ + T +S+ Sbjct: 3593 ASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVT-ISE 3651 Query: 1149 ILKMSLMEAQIDTNV--EHMIVDPPKKALATSM--LTGEAGSLPSTHMVVAGMANSTPQQ 1204 S + T V + P T+M T GS P T M V+ +T Sbjct: 3652 AGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVS----TTRVT 3707 Query: 1205 QKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYA 1264 + S+PS V S+ T + + AT + + I++ P Sbjct: 3708 SSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTR 3767 Query: 1265 IPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS 1322 P S+ ++ PS +TS + TA E +T +GT P +++ERS Sbjct: 3768 FPESSTPSI---PSV------YTSMSMT---TASEGSSSPTTLEGTTTMPMSTTSERS 3813 Score = 105 bits (262), Expect = 3e-22 Identities = 247/1190 (20%), Positives = 434/1190 (36%), Gaps = 145/1190 (12%) Query: 88 SSSEWSIEGRRLVPLMPR--LVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYS 145 +SS + EG + P P T+ V+ VAN+ ++ PV + T Sbjct: 962 TSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNT--------- 1012 Query: 146 YTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCS-----DEDEK 200 TTST S+P P+ ++ + P+ ++ + +P +T+ S + + + Sbjct: 1013 -PLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTST 1071 Query: 201 PRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVK 260 P SSSS+ +P + T V S ++ ++ S P + + Sbjct: 1072 PVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIP 1131 Query: 261 ITFTKPSTQTTNTTTQKVIIVTTSPSSTFVP---------NILSKSHNYAAVTKLVPTSV 311 +T T ++ TT + I T+ PS P ++S N + T + + Sbjct: 1132 VT-TSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQ 1190 Query: 312 IASTTQKPPVVITASQSSL-VSNSSSGSSSSTPSPIPNTVAVT---AVVSSTPSVVMSTV 367 +A++T+ TA +S+ S S+ T P+ +T + + +S++P + V Sbjct: 1191 VATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPV 1250 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQ--QSPK-QQLYQVQQQTQQQVA 424 TS+ + P S S + +L P SP+ L T+ V Sbjct: 1251 TTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVV 1310 Query: 425 QPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSP 484 + VS P + P + + + + T V S I + +T P +++P Sbjct: 1311 TSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAI---SILSTTPVDNSTP 1367 Query: 485 IMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVP 544 + +T+ ++PT ++ T + P +PS G TP + V TT VV Sbjct: 1368 VTT--------STEACSSPTTSEGT-SMPNSNPSEG---TTPLTSIPVSTT-----PVVS 1410 Query: 545 KSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLL 604 +TL + ++ T+ + T+ P T++ I + T ++ +P N T + Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN--TPVA 1468 Query: 605 NAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKT 664 N+ T+ T P + ++T+T + S+ PA +G + Sbjct: 1469 NSEA-STLSTTPVDSNSPVVTST------------AVSSSPTPA------------EGTS 1503 Query: 665 QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724 + P + T + T + + + S ++ + + + T + +S Sbjct: 1504 IAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSM 1563 Query: 725 ESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ 784 ++S S+ S P+ + S S + T+P V++ +++++ST + Sbjct: 1564 QTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTI 1623 Query: 785 TTVKE---KLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERT 841 +T E L S P T S A + T +SP S V S AE T+ T Sbjct: 1624 STPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEG-TSMPT 1682 Query: 842 DEGTEVAFPLL-VSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHI 900 TE PL ++ R+ P S TL + T TS +S P +S G Sbjct: 1683 STYTEGRTPLTSITVRTTP-VASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGT---S 1738 Query: 901 MQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE 960 M + S S + T E TL T + + +T S A S E Sbjct: 1739 MPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS-ATPIDTSTPVTTSTEATS---SPTTAE 1794 Query: 961 QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQH 1020 T + TL T L + + H L + S TP+ P V Sbjct: 1795 GTSIPTSTLSEGMTP------LTSTPVSHTLVANSEAST--LSTTPVDSN----SPVVTS 1842 Query: 1021 T---QHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQ-QLPKLQQAPNQPKIYVQPQTPQS 1076 T P A+ + T T + + V TT + P + P T + Sbjct: 1843 TAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYA 1902 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSV-TKITFEGRQPPTVTKITGGSSVPKLTSPVTSI 1135 Q+S P GSS+ T EGR P T + S+ +S + ++ Sbjct: 1903 QVS-------------SSPTTADGSSMPTSTPREGRPPLTSIPV---STTTVASSEINTL 1946 Query: 1136 SPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLP-STHMVV 1194 S A +T V+ + S T + + P + ++ LT S+P ST +VV Sbjct: 1947 STTLADTRTPVTTYSQAS----SSPTTADGTSMPTPAYSEGSTPLT----SMPLSTTLVV 1998 Query: 1195 AGMAN---------STPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATG 1235 + A+ STP S S + G+S+ T P G Sbjct: 1999 SSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAG 2048 Score = 105 bits (262), Expect = 3e-22 Identities = 251/1225 (20%), Positives = 448/1225 (36%), Gaps = 142/1225 (11%) Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTS-TPVPSGSIATV 166 P T V+ VA++ + + PA+T S V YS S++ST T +P+ + + Sbjct: 1043 PLTRMPVSTTMVASS--ETSTLSTTPADT-STPVTTYSQASSSSTTADGTSMPTSTYSEG 1099 Query: 167 KSPRPASPASNVVVLPSGSTVYVKS-------VSCSDEDEKPRKRRRTNSSSSSPVVLKE 219 +P + P S +V+ S ++ + V+ S E S +SP Sbjct: 1100 STPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGT 1159 Query: 220 VPKAVVPVSKTI----------TVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQ 269 P A +PVS T+ T PV +++ + A+S PP + + P + Sbjct: 1160 TPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE--ASSPPPTAEVTSMPTSTPGER 1217 Query: 270 TTNTTTQKV----------IIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKP 319 +T T+ V ++TSP T P + + + ++ T TS+ STT + Sbjct: 1218 STPLTSMPVRHTPVASSEASTLSTSPVDTSTP-VTTSAETSSSPTTAEGTSLPTSTTSEG 1276 Query: 320 PVVITAS--QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIK 377 ++T+ ++LV++ + + +TP V + VSS+P+ T + S + Sbjct: 1277 STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGR 1336 Query: 378 MASTRLPSPKSLV-SAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQ-VAQPSPVSHQQQP 435 T +P +LV S+ IL+ P + T + + P+ + Sbjct: 1337 TPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTT 1396 Query: 436 QQSPLPPGIKPTIQIKQES----GVKIITQQVQPSKILPKPVTA---TLPTSSNS----P 484 + +P P + + + V T ++ P TA ++PTS+ S P Sbjct: 1397 PLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTP 1456 Query: 485 IMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGS----II 540 + + + + +T + T P V+ + + TP T + ++ S + Sbjct: 1457 LKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTAL 1516 Query: 541 TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQ-------- 592 T +P S T+ I+S TT +T+ P+T+ TT GT++Q Sbjct: 1517 TSIPVSTTTVASSEINS---LSTTPAVTSTPVTTYSQASS-SPTTADGTSMQTSTYSEGS 1572 Query: 593 -GLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651 L V T L+ + T+ T P +K + +T + T +G T+ ++ Sbjct: 1573 TPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSS---TTAEGSSMTISTPSEG 1629 Query: 652 IPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGN---SSIQE 708 P ++ T + P+ T T V + + + + + AE + S+ E Sbjct: 1630 SP--LLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTE 1687 Query: 709 GKEEPQNYT------DSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIY 762 G+ + T SS+ ST S+ +S PV +R + +M S Sbjct: 1688 GRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNS----- 1742 Query: 763 QDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESP 822 + S +T + + T V S ID S P+ + E SP + Sbjct: 1743 ------TPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTS---TPVTTSTEATSSPTTA 1793 Query: 823 SIAVVESELVAEYIT--TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTAT 880 + + ++E +T T T VA + + P + P T V+ S T Sbjct: 1794 EGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTA-VSSSPTPA 1852 Query: 881 QTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYR 940 + + + S P+ A+T I +S+ T + + L T T Q Sbjct: 1853 EGTSIATSTPSEGSTALTSI---PVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPT 1909 Query: 941 SALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQ----------TKQKQTIHLQADQLQHK 990 +A S + +PPL + T+ + T+ T + QA Sbjct: 1910 TADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQAS----- 1964 Query: 991 LPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQ----LPTLMAQPPQTVVQV 1046 P + TP E + P + + +V+ + P + P T + Sbjct: 1965 --SSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEG 2022 Query: 1047 LAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTK- 1105 + TT +Q + + P S +L SSE T S TQ ++ T+ Sbjct: 2023 SSSPTTAGGTSIQTSTPSERTTPLAGMPVS-TTLVVSSEGNTLSTTPVDSKTQVTNSTEA 2081 Query: 1106 ---ITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTN 1162 T EG T++ + GS P LTS S +P+ + E + +S S T Sbjct: 2082 SSSATAEG-SSMTISAPSEGS--PLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTE 2138 Query: 1163 VEHMIVDPPKKALATSMLTGE---AGSLPSTHMVVAGMA----------NSTPQQQKCRE 1209 V + ++ TS + S+P + VVA A STP Sbjct: 2139 VSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198 Query: 1210 SCSSPSTVGSSLTTRKIDPPAVPAT 1234 S ++ G+S+ T + P T Sbjct: 2199 RSSPTTSEGTSMPTSTPSEGSTPFT 2223 Score = 101 bits (252), Expect = 4e-21 Identities = 257/1251 (20%), Positives = 446/1251 (35%), Gaps = 162/1251 (12%) Query: 83 MSGPNSSSEWSIEGRRLVPLMPR--LVPQTAFTVTANAVANAAIQHNASLPVPAETGSKE 140 +S SSS + EG L P P T ++ V ++ + + PA T Sbjct: 249 ISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSS--EASTLSTTPAATNIPV 306 Query: 141 VVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSG-STVYVKSVSCS---- 195 + +S+ +T T +P+ + +P ++PAS + V S ST+ + V S Sbjct: 307 ITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVT 366 Query: 196 ---DEDEKPRKRRRTN------SSSSSPVVLKEVPKAVV---PVSKTITVPVSGSPKMSN 243 + P T+ S S+P+ V +V S T T+PV ++ Sbjct: 367 TSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTT 426 Query: 244 IMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAV 303 S A+S P I + PS +T T+ V+T+P ++ S++ N + Sbjct: 427 --ASEASSSPTTAEDTSIATSTPSEGSTPLTSMP---VSTTPVAS------SEASNLSTT 475 Query: 304 TKLVPTSVIAST--TQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS 361 T V ST + PP TA +S+ +++ S S+ S +T+ V + +ST S Sbjct: 476 PVDSKTQVTTSTEASSSPP---TAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLS 532 Query: 362 VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421 + V+TS+ +S+ P S+ PT ++ P V + Sbjct: 533 TTPVDTSTPVTTSSEASSSSTTPEGTSI---PTSTPSEGSTPLTNMPVSTRLVVSSEAST 589 Query: 422 QVAQPSP-----VSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT-- 474 P+ + + S G E G I + V + + + Sbjct: 590 TSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTL 649 Query: 475 ATLPTSSNSPIMVVSSNGAIMTTKLVTT-PTGTQATYTRPTVSPSIGRMAATPGAATYVK 533 +T P SN+P+ + + TT T+ PT T + P S + A+ + Sbjct: 650 STTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLS 709 Query: 534 TTSGSIITVVPKSLATLGGKIISSNIVSGTTTKIT-TIPMTSKPNVIVVQKTTGKGTTIQ 592 TT T V S + T+T + P+TS P V T+ + +T+ Sbjct: 710 TTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP-VSKTLLTSSEASTLS 768 Query: 593 GLP--GKNVVTTLLNAG-----GEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTV 645 P +TT A E T + T ++ + L + P++ VT P+ + Sbjct: 769 TTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLST 828 Query: 646 QPAAKIIPTKIVYGQQGKTQVLIKPKP---VTFQATVVSE----------QTRQLVTETL 692 P P T+V P P + + SE T + T + Sbjct: 829 TPVDSNSPVTT------STEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAI 882 Query: 693 QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVH-------VIASRRQ 745 S ++ + E + T S +S +S + S P+ V++S + Sbjct: 883 STLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEAR 942 Query: 746 DWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQM 805 S + T T + SS + + ++I + TT L S P T+ + Sbjct: 943 TLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTT---PLTSTPVSHTLVANSE 999 Query: 806 AVPIQMTQEKRHSPESPSIAVVESELVAE--YITTERTDEG-----------TEVAFPLL 852 A + T ++P + S AE + T EG T VA Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET 1059 Query: 853 VSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVK-----SIPASSPGAITHIMQQALSS 907 + + P S P T Q + S TA TS+ S P +S T ++ + +S Sbjct: 1060 STLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119 Query: 908 H------------TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQ----SAKQ 951 T T+ S T EG + T P G +++ S S++ Sbjct: 1120 TLSTTPVDTSIPVTTSTEASSSPTTAEG--TSIPTSPPSEGTTPLASMPVSTTLVVSSEA 1177 Query: 952 QKLSQPPLE-QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQE 1010 LS P++ +TQ+ T + + + + + +RH + + Sbjct: 1178 NTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEAS 1237 Query: 1011 QAQPKP---------DVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQA 1061 P + + P A+ LPT T++ + V TT L + Sbjct: 1238 TLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTT-----LVTS 1292 Query: 1062 PNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITF-EGRQP----PTV 1116 P + P + P + + +S P +G+S+ T+ EGR P P Sbjct: 1293 PEASTLLTTPVDTKG----PVVTSNEVSS---SPTPAEGTSMPTSTYSEGRTPLTSIPVN 1345 Query: 1117 TKITGGSSVPKL-TSPVTSISPIQASEKTAVSDILK--MSLMEAQIDTNVEHMIVDPPKK 1173 T + S++ L T+PV + +P+ S + S S+ + + P Sbjct: 1346 TTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIP--- 1402 Query: 1174 ALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTV-GSSLTT 1223 T +++ EA +L +T + STP E+ SSP+T G S+ T Sbjct: 1403 VSTTPVVSSEASTLSAT-----PVDTSTPGTTSA-EATSSPTTAEGISIPT 1447 Score = 95.1 bits (235), Expect = 4e-19 Identities = 234/1181 (19%), Positives = 412/1181 (34%), Gaps = 144/1181 (12%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206 T+T +T T+ P ++ +P S S+V + T V S + + + Sbjct: 67 TATGTTSTNVVEPRMYLSCSTNPEMTSIESSV----TSDTPGVSSTRMTPTESRTTSEST 122 Query: 207 TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANS-LPPHMSPVKITFTK 265 ++S++ P ++ P + + +S+ M ++ + LP + +T+ K Sbjct: 123 SDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTY-K 181 Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325 T TT+ + T+P ST +P KS N T L TS+ AST + Sbjct: 182 VDMSTPLTTSTQASSSPTTPESTTIP----KSTNSEGSTPL--TSMPASTMK-------- 227 Query: 326 SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP- 384 V++S + + +TP I V ++A SS+P+ + S TR+P Sbjct: 228 -----VASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPL 282 Query: 385 SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGI 444 S +VS+ L+ P A PV + SP Sbjct: 283 SVMLVVSSEASTLSTTP---------------------AATNIPVITSTEASSSP----- 316 Query: 445 KPTIQIKQESGVKIITQ-QVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTP 503 G I T + S L +T+P +++ M S + T+ LVTT Sbjct: 317 ------TTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSE--MSTLSITPVDTSTLVTTS 368 Query: 504 TGTQATYTRPTVSPSIGRMAAT-PGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562 T + PT + + + +T +T + S I V +T + S Sbjct: 369 TEPSSL---PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVT 425 Query: 563 TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPA 622 T ++ ++ P T++ I + T + +P V TT + + + T P +K Sbjct: 426 TASEASSSPTTAEDTSIATSTPSEGSTPLTSMP---VSTTPVASSEASNLSTTPVDSKTQ 482 Query: 623 ILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSE 682 + T+T S+ P A++ +G T + T +S Sbjct: 483 VTTSTE-------------ASSSPPTAEVNSMPTSTPSEGSTPL-----------TSMSV 518 Query: 683 QTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIAS 742 T + + S ++ + E + T +S +S S+ S P+ ++ S Sbjct: 519 STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVS 578 Query: 743 RRQDWSEHEIAMETSP--TIIYQDVSSESQSATSTIKALLELQQTTVKEK---LESKPRQ 797 R S T+P + + SSE+ S+++T + + +T E+ + S Sbjct: 579 TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEG-TSMPTSTYSERGTTITSMSVS 637 Query: 798 PTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRS 857 T+ S A + T ++P + S S AE T+ T TE + PL + Sbjct: 638 TTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG-TSMPTSTYTEGSTPLTSMPVN 696 Query: 858 QPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAI--THIMQQALSSHTAFTKHS 915 S TL + T TS S P ++ GA T + + T+ Sbjct: 697 TTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSK 756 Query: 916 EELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQ---QKLSQPPLEQTQLQVKTLQCF 972 L + E LD T + + + S + + +S P L + Sbjct: 757 TLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSIT 816 Query: 973 QTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQL 1032 + L + P + TP + + P + P+ + Sbjct: 817 PVTSPEASTLSTTPVDSNSPVTTSTEVSSSP-TP-AEGTSMPTSTYSEGRTPLTSMPVS- 873 Query: 1033 PTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQ--------MSLPASS 1084 TL+A + + V T+ + +A + P P S S+P S+ Sbjct: 874 TTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDST 933 Query: 1085 EKQTASQVEQPIITQGSSVTKIT--FEGRQPPTVTKITGGSSVPKLTSPVTSISPIQAS- 1141 +S+ T + T +T E PT + G+S+P T P +P+ ++ Sbjct: 934 TPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAE---GTSIPTST-PSEGTTPLTSTP 989 Query: 1142 -EKTAVSDILKMSLMEAQIDTN----VEHMIVDPPKKALATSMLTG--EAGSLPSTHMVV 1194 T V++ +L +D+N PP A TSM T GS P T M V Sbjct: 990 VSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPV 1049 Query: 1195 AGMA---------------NSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMR 1239 + STP + S SS + G+S+ T + P T + Sbjct: 1050 STTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVS 1109 Query: 1240 IQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGL 1280 + V +A + +IP SSS E + + Sbjct: 1110 TRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSI 1150 Score = 90.5 bits (223), Expect = 1e-17 Identities = 166/801 (20%), Positives = 301/801 (37%), Gaps = 82/801 (10%) Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204 S STT TSTPV + + A++ SP A S PS T + S+ S P Sbjct: 3358 STLSTTPVDTSTPVTTSTEASL-SPTTAEGTSIPTSSPSEGTTPLASMPVSTT---PVVS 3413 Query: 205 RRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGS-PKMSNIMQSIANSLPPHMSPVKITF 263 N+ S++PV + S + T+ S P + S S+ P +S + Sbjct: 3414 SEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMP-LSTTPVAS 3472 Query: 264 TKPSTQTTNTTTQKVIIVTTSP--SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPV 321 ++ ST +T + T+SP SS + S + A T++ STT Sbjct: 3473 SEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASS 3532 Query: 322 VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381 + ++ V +++ +SSS S P T+ VT + STPS S++ + +S +S Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSE 3592 Query: 382 RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLP 441 V T + +P + + + T +V+ P + + Sbjct: 3593 ASTPSTPSVDRSTPVTTSTQSNSTPTPPEVI-TLPMSTPSEVSTPLTIMPVSTTSVTISE 3651 Query: 442 PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATL--PTSSNSPIMVVSSNGAIMTTKL 499 G T+ + + V I + QV S + P+ T + P+ ++P+ + + TT++ Sbjct: 3652 AGTASTLPVDTSTPV-ITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMP----VSTTRV 3706 Query: 500 VTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNI 559 ++ T +T + T +P A +AT TT +P ++TLG I+ S Sbjct: 3707 TSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMS---VSMPMEISTLGTTILVS-- 3761 Query: 560 VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGA 619 TT +T P +S P++ V + T +G + TTL G T+ T Sbjct: 3762 ----TTPVTRFPESSTPSIPSVYTSMSMTTASEG---SSSPTTL---EGTTTMPMSTTSE 3811 Query: 620 KPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATV 679 + +LT T I+ + V P + P + + G I + T + ++ Sbjct: 3812 RSTLLT-TVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFS--IPAEVTTIRISI 3868 Query: 680 VSEQ----TRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST-------ESSQ 728 SE+ T LV+ TL + A ++ + TD++S+ T S Sbjct: 3869 TSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSV 3928 Query: 729 SSQDSQPVVHV------IASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLEL 782 ++ S P + + S D ++P I ++++ S S++ST + Sbjct: 3929 ITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT 3988 Query: 783 QQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTD 842 ++ T + P T A T + + + +++ + + +TT Sbjct: 3989 KEFTTPAMTTAAPL--TYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVT 4046 Query: 843 EGTEVAFP-LLVSHRSQPQQP----------------------------SQPQRTLLQHV 873 +E + P + SH P P ++P Sbjct: 4047 PSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFP 4106 Query: 874 AQSQTATQTSVVVKSIPASSP 894 + TA T+ +KS P S+P Sbjct: 4107 TVTTTAVPTNTTIKSNPTSTP 4127 Score = 89.0 bits (219), Expect = 3e-17 Identities = 233/1146 (20%), Positives = 418/1146 (36%), Gaps = 153/1146 (13%) Query: 95 EGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPT 154 EG L+ +P A + A+ ++ + N+ + E S + TST T Sbjct: 1628 EGSPLLTSIPVSTTPVA-SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYT 1686 Query: 155 STPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSP 214 P SI +P +S S + P ++ V + ++ P T+ +S+P Sbjct: 1687 EGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPV--TTSTEARSSPTTSEGTSMPNSTP 1744 Query: 215 VVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTT 274 + P++ ++PVS +P +S+ +++ + +PV T + T++ T Sbjct: 1745 ------SEGTTPLT---SIPVSTTPVLSSEASTLSATPIDTSTPV----TTSTEATSSPT 1791 Query: 275 TQKVIIVTTSPSSTFVPNILSK--SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVS 332 T + + TS S + + S SH A ++ S + P V TA SS Sbjct: 1792 TAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSS--P 1849 Query: 333 NSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSA 392 + G+S +T +P + A+T++ ST +V S +T A+ ST + + + S+ Sbjct: 1850 TPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAV--TSTPVTTYAQVSSS 1907 Query: 393 PTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQ 452 PT T + P+ + +P + +P Sbjct: 1908 PT------------------------TADGSSMPTSTPREGRPPLTSIP----------- 1932 Query: 453 ESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTR 512 + T V S+I +T + +P+ S + TT GT + Sbjct: 1933 -----VSTTTVASSEI---NTLSTTLADTRTPVTTYS-----QASSSPTTADGT----SM 1975 Query: 513 PTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPM 572 PT + S G +TP + + TT VV +TL + ++ + T+T+ ++ P Sbjct: 1976 PTPAYSEG---STPLTSMPLSTT-----LVVSSEASTLSTTPVDTSTPATTSTEGSSSPT 2027 Query: 573 TSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITK 632 T+ I + + T + G+P V TTL+ + T+ T P +K + +T + Sbjct: 2028 TAGGTSIQTSTPSERTTPLAGMP---VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSS 2084 Query: 633 MIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETL 692 GS++ +A + ++ T + P+ T T V + ++T T Sbjct: 2085 ATAE-----GSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPV-DSNSPVITSTE 2138 Query: 693 QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEI 752 +S + G S + Y+D + T S PV + + S Sbjct: 2139 VSSSPIPTEGTSM------QTSTYSDRRTPLT--------SMPVSTTVVA-----SSAIS 2179 Query: 753 AMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMT 812 + T+P D S+ ++T + + T++ S+ P + +P+ +T Sbjct: 2180 TLSTTPV----DTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPV-VT 2234 Query: 813 QEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQH 872 E +P E ++ T EGT + L S + P TL Sbjct: 2235 SEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTL-SEGTTPLTSIPVSHTL--- 2290 Query: 873 VAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLD 932 VA S+ +T + + P S T + + TA + EG T Sbjct: 2291 VANSEVST-----LSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL--TRM 2343 Query: 933 PQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLP 992 P + S T + S S P +Q T + + + +P Sbjct: 2344 PVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVP 2403 Query: 993 --QMPQLSIRHQKLTPLQQEQAQP-KPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAV 1049 MP +S + + + P + + P A+ +PT T + + V Sbjct: 2404 VSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV 2463 Query: 1050 KTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFE 1109 TT + +A V TP + S ASS TA + PI T T +T Sbjct: 2464 STTPVVS--SEAGTLSTTPVDTSTPMT-TSTEASSSPTTAEDIVVPISTASEGSTLLT-- 2518 Query: 1110 GRQPPTVTKITGGSSVPKLTSPVTSISPIQ-----ASEKTAVSDILKMSLMEAQIDTNVE 1164 P + T + + T+PV S SP+ +S T+ + ++ T + Sbjct: 2519 -SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR 2577 Query: 1165 HMIVDPPKKALATSMLTGEAGSLPST------HMVVAGMANSTPQQQK-CRESCSSPSTV 1217 M V K LA+S EA +L +T + + +S+P K S+PS V Sbjct: 2578 SMPVS--TKPLASS----EASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEV 2631 Query: 1218 GSSLTT 1223 +SLT+ Sbjct: 2632 STSLTS 2637 Score = 86.3 bits (212), Expect = 2e-16 Identities = 173/786 (22%), Positives = 289/786 (36%), Gaps = 101/786 (12%) Query: 78 TIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETG 137 TIA S P S++ ++PL V + + + + + S P + Sbjct: 3441 TIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPT 3500 Query: 138 SKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDE 197 + EV S ++T+ STP+ + ++T +P +S AS + P S +V S S + Sbjct: 3501 TAEVT--SMPTSTAGEGSTPLTNMPVST--TPVASSEASTLSTTPVDSNTFVTSSSQASS 3556 Query: 198 D----EKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVP---VSGSPKMSNIMQSIAN 250 + R T S SS + + V S+ T V S ++ QS + Sbjct: 3557 SPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNST 3616 Query: 251 SLPPHM--------SPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAA 302 PP + S V T TT+ T + +T P T P I S + + Sbjct: 3617 PTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSP 3676 Query: 303 VTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSV 362 VT T I + ++ + T S+ SS GS+ STPS + +T T+ + + S Sbjct: 3677 VTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSA 3736 Query: 363 VMSTVAQGVST--------SAIKMAS---TRLP--SPKSLVSAPTQILAQFPKQHQQSP- 408 + + VS + I +++ TR P S S+ S T + + SP Sbjct: 3737 TLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPT 3796 Query: 409 -------KQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPL--PPGIKPTIQI--------- 450 ++ T SP+S + S L PPG T + Sbjct: 3797 TLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFS 3856 Query: 451 --KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQA 508 + + ++I + + + V+ TLPTS P ++S + T+ T T T + Sbjct: 3857 IPAEVTTIRISITSERSTPLTTLLVSTTLPTS--FPGASIASTPPLDTSTTFTPSTDTAS 3914 Query: 509 TYTRP---TVSPSIGRMAATPGAATYVKTT--SGSIITVVPKSLATLGGKIISSNIVS-- 561 T T P T+S S+ +TPG ++ +T + S V P + + +I+S ++ Sbjct: 3915 TPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTP 3974 Query: 562 -----------GTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNA-GGE 609 TT + TT MT+ + V +T T G + L+A Sbjct: 3975 STSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTP 4034 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIK 669 T +V T ++RP T T P T PA P + + Sbjct: 4035 HTSTSVTTRPVTPSSESSRPSTITSHTIP----PTFPPAHSSTPP-----TTSASSTTVN 4085 Query: 670 PKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQS 729 P+ VT T TR T + + A N++I K P + ++T Sbjct: 4086 PEAVTTMTTRTKPSTR---TTSFPTVTTTAVPTNTTI---KSNPTSTPTVPRTTTCFGDG 4139 Query: 730 SQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA-----TSTIKALLELQQ 784 Q++ ASR ++ + P + Y ++ E S+ TI A +EL Sbjct: 4140 CQNT-------ASRCKNGGTWDGLKCQCPNLYYGELCEEVVSSIDIGPPETISAQMELTV 4192 Query: 785 TTVKEK 790 T K Sbjct: 4193 TVTSVK 4198 Score = 85.5 bits (210), Expect = 3e-16 Identities = 213/1033 (20%), Positives = 364/1033 (35%), Gaps = 122/1033 (11%) Query: 76 LTTIAHNMSGPNSSSEWSI------EGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNAS 129 +TT S P +S S+ EG + MP T V++ +A + S Sbjct: 3136 VTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP---VSTMLVVSSEDSTLSATPVDTS 3192 Query: 130 LPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYV 189 PV T S E + TS PTSTP +P + P SN V S +++ Sbjct: 3193 TPV---TTSTEATSSTTAEGTSIPTSTPSEG------MTPLTSVPVSNTPVASSEASI-- 3241 Query: 190 KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249 +S + D T +SSS P S + P GS ++++ S Sbjct: 3242 --LSTTPVDSNTPLTTSTEASSS--------PPTAEGTSMPTSTPSEGSTPLTSMPVSTT 3291 Query: 250 NSLPPHMSPVKITFTKPSTQTTN----TTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK 305 S + T ST T +++ + T+ P+ST+ ++ + T Sbjct: 3292 TVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTP 3351 Query: 306 LVPTSVIASTTQKPPV-----VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP 360 +V + AST PV V T++++SL ++ G+S T SP T + ++ ST Sbjct: 3352 VVSSE--ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTT 3409 Query: 361 SVVMSTV----AQGVSTSAIKMASTRLPSPKSL---VSAPTQILAQFPKQHQQSPKQQLY 413 VV S V V ++ + ST S ++ S PT ++ P Sbjct: 3410 PVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTP 3469 Query: 414 QVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV 473 + P S P + P PT + + + T + + PV Sbjct: 3470 VASSEASTLSTTPVDTS---TPVTTSSPTNSSPT--TAEVTSMPTSTAGEGSTPLTNMPV 3524 Query: 474 TATLPTSSNSPIM---VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPG--A 528 + T SS + + V SN + ++ ++ T T +PS G + T + Sbjct: 3525 STTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLS 3584 Query: 529 ATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKG 588 +TYV ++ S + +T SN + T ++ T+PM++ V Sbjct: 3585 STYVTSSEASTPSTPSVDRSTPVTTSTQSN-STPTPPEVITLPMSTPSEV---------S 3634 Query: 589 TTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATR----PITKMIVTQP---KGI 641 T + +P T+ AG T T+P ++T+T+ P+T T P Sbjct: 3635 TPLTIMPVSTTSVTISEAG---TASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSE 3691 Query: 642 GSTVQPAAKIIPTKIV--YGQQGKTQVLIKPKPVTFQATVVSEQ-TRQLVTETLQQASRV 698 GST + T++ G T ++ PVT +S T T ++ + Sbjct: 3692 GSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEI 3751 Query: 699 AEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIAS--RRQDWSEHEIAMET 756 + G + + S++ T +SS S P V+ S + S +E Sbjct: 3752 STLGTTILV-----------STTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEG 3800 Query: 757 SPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKR 816 + T+ S S T+ + + + + + L + P + L +T K Sbjct: 3801 TTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPL--------LTSTKA 3852 Query: 817 HSPESPSIAVVESELVAEYITTERTDEGTE--VAFPLLVSHRSQPQQPSQPQRTLLQHVA 874 S P+ E + IT+ER+ T V+ L S + P T Sbjct: 3853 GSFSIPA----EVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTP 3908 Query: 875 QSQTATQTSVVVKS-------IPASSPGAITHIMQQALSSHTA--FTKHSEELGTEEGEV 925 + TA+ ++ V + S+PG I ++S TA F + + T Sbjct: 3909 STDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITS 3968 Query: 926 EEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQAD 985 E++T + S T + + PL T + + T + A Sbjct: 3969 TELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPL--TYVTMSTAPSTPRTTSRGCTTSAS 4026 Query: 986 QLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMV--AKDRQLPTLMAQPPQTV 1043 L S+ + +TP E ++P HT P A PT A Sbjct: 4027 TLSATSTPHTSTSVTTRPVTP-SSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVN 4085 Query: 1044 VQVLAVKTTQQLP 1056 + + TT+ P Sbjct: 4086 PEAVTTMTTRTKP 4098 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 94.4 bits (233), Expect = 7e-19 Identities = 257/1293 (19%), Positives = 470/1293 (36%), Gaps = 186/1293 (14%) Query: 53 SKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAF 112 S+V S T+R+ ++ TIA ++ P + + +I + P + RLV Sbjct: 10739 SQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVT 10798 Query: 113 TVTA-NAVANAAIQHNASLPV--------PAETG------------SKEVVCYSYTSTTS 151 ++ A + N A+ ++ P PA+T SK S T++ Sbjct: 10799 SLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHG 10858 Query: 152 TPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSS 211 +S+ VP+ +++T + P +P +T+ + ++S + + P + Sbjct: 10859 AESSSAVPTPTVST-EVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEA 10917 Query: 212 SS----PVVLKEVPKAV---VPVSKTI---TVPV--------SGSPKMSNIMQSIANSLP 253 SS P V VP V V S+ + T+P+ +P M+ + A S Sbjct: 10918 SSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAV 10977 Query: 254 PHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIA 313 P + P P T+ + + + TT P+ T P + + A +S + Sbjct: 10978 PTVLP-----EVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVP 11032 Query: 314 STTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQG--- 370 + + + P V+T SLV++SS +S+S IP + + +TPS+ S A+ Sbjct: 11033 TVSPEVPGVVT----SLVTSSSGVNSTS----IPTLILSPGELETTPSMATSHGAEASSA 11084 Query: 371 -----VSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQ 425 VS + + + S +++ S IL + + +P T V Sbjct: 11085 VPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTP-------SMATSHGVEA 11137 Query: 426 PSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS----- 480 S V SP PG+ ++ + + S P+ T+ + S Sbjct: 11138 SSAVL-----TVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMI 11192 Query: 481 SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPS----IGRMAATPGAATYVKTTS 536 S P + VS + T LVT+ + ++ TV+ S I A PG + Sbjct: 11193 SAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPT 11252 Query: 537 GSIITVVP-KSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIV---VQKTTGKGTTIQ 592 ++ T P +++ + SS+ + TT++ + + + P+ + + ++ TTI Sbjct: 11253 LTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTIS 11312 Query: 593 -GLPGKNVVTTLLNAGG---EKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPA 648 G+PG V+T+L+ + G T TVP + TA+ VT P + ST P Sbjct: 11313 PGIPG--VLTSLVTSSGRDISATFPTVPESPHESEATAS------WVTHP-AVTSTTVPR 11363 Query: 649 AKIIPTKIVYGQQGKTQVLIKPKP-----VTFQATVVSEQTRQLVTETLQQASRVAEAGN 703 T + T I P F VS +VT + + Sbjct: 11364 T----TPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITI 11419 Query: 704 SSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQ 763 ++ EP+ T S T S + + P + V + + I+ T T + Sbjct: 11420 PTLTLSSGEPETTT---SFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFP 11476 Query: 764 DVS-SESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQ---EKRHSP 819 ++ + + T+ I+ + + T+ + K D + +P+ +T E + Sbjct: 11477 TLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTT---LPVAITSPGPEASSAV 11533 Query: 820 ESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTA 879 + +I+ S+LV + + TD T FP L +P+ + T L H A++ T Sbjct: 11534 STTTISPDMSDLVTSLVPSSGTD--TSTTFPTLSETPYEPETTA----TWLTHPAETSTT 11587 Query: 880 --------------------------TQTSVVVKSIPASSPGAIT-HIMQQALSSHTAFT 912 T++ V +IP S PG +T + A + TA Sbjct: 11588 VSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIP 11647 Query: 913 KHSEELGTEEGEVEEMDTLDPQTGLF--YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQ 970 + G E QTG R+ + ++ PP T + +T Sbjct: 11648 TLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVS-RTTS 11706 Query: 971 CFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDR 1030 F + A P+ LT + P+ A Sbjct: 11707 SFSHSSPDATPVMATS--------PRTEASSAVLTTI--SPGAPEMVTSQITSSGAATST 11756 Query: 1031 QLPTLMAQP--PQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088 +PTL P P+T A+ +T P+ + + P V PQ ++ SL +T Sbjct: 11757 TVPTLTHSPGMPETT----ALLSTH--PRTETSKTFPASTVFPQVSETTASLTIRPGAET 11810 Query: 1089 ASQVEQPIITQGSSVTKI---TFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTA 1145 ++ + P T S T + T PT + + P T P T S + + + Sbjct: 11811 STAL--PTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLS 11868 Query: 1146 VSDILKMSLM----EAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANST 1201 + + L+ A+ T+ + V P L+++ +T + P T V + ++ Sbjct: 11869 LGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDK---PQT--VTSWNTETS 11923 Query: 1202 PQQQKCRESCSSPSTVGSSLTTRKIDPPAVPAT 1234 P S + G+++T + P P T Sbjct: 11924 PSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKT 11956 Score = 91.7 bits (226), Expect = 4e-18 Identities = 263/1312 (20%), Positives = 485/1312 (36%), Gaps = 186/1312 (14%) Query: 88 SSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYT 147 SSS SI+G P + P T+ A + + + +TG T Sbjct: 6405 SSSRTSIQGTE----KPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRA-----T 6455 Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 S + T + + T + ++ L S Y+ S P +T Sbjct: 6456 SQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTS-------PPSVEKT 6508 Query: 208 NSSSSS---PVVLKEVP-KAVVPVSKT------ITVPVSGSPKMSNIMQSIANSLPPHMS 257 +SSSS P + P +P S+ ++P SG K ++++ S+A SLPP++ Sbjct: 6509 SSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVA-SLPPNLG 6567 Query: 258 PVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQ 317 P+T T+K+ +T+ + T V S+ +Y++V + S Sbjct: 6568 STSHKI--PTTSEDIKDTEKMY-PSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTS--- 6621 Query: 318 KPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVT-----------AVVSSTPSVVMST 366 P V + ++VS S GSS T + +T ++ +VS+ S V+ Sbjct: 6622 -PMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHK 6680 Query: 367 VAQGVS-TSAIKMASTR---LPSPKSLVSAP---TQILAQFPKQ---------------- 403 + G + TS ++AS+R +P P +P T+++ P Sbjct: 6681 LTTGATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTG 6740 Query: 404 -HQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQS--------------PLPPGIKPTI 448 S Q + + T A ++ Q+ P +PP I+ T Sbjct: 6741 PPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTS 6800 Query: 449 QIKQESGVKIITQQVQPSKILPKP-VTATLPTSSN---SPIMVVSSNGAIMTTK-LVTTP 503 + + PS + P V++TLP + + SP+ + + +MTT L T+P Sbjct: 6801 ----------FSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSP 6850 Query: 504 TGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGT 563 T T + P +S + + T T ++ S T T G S++++ + Sbjct: 6851 EPT--TSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADS 6908 Query: 564 TTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAI 623 T PM + + +T + + K T L G +T + Sbjct: 6909 EKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRET----SISQNASF 6964 Query: 624 LTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQ 683 T T + + T G+T A++ T++ G+T + P Q+TV+ E Sbjct: 6965 STDTSIVLSEVPT-----GTT----AEVSRTEVT--SSGRTSI-----PGPSQSTVLPEI 7008 Query: 684 TRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASR 743 + + +T L + + E+ +I + P T + + ++S + SQ H ++ Sbjct: 7009 STRTMTR-LFASPTMTESAEMTIPT-QTGPSGSTSQDTLTLDTSTTK--SQAKTHSTLTQ 7064 Query: 744 RQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLS 803 R SE M P + SS S S++ +LL L TT + S TI S Sbjct: 7065 RFPHSEMTTLMSRGPGDMSWQ-SSPSLENPSSLPSLLSLPATTSPPPISST-LPVTISSS 7122 Query: 804 QMAV-------PIQMTQEKRHSPESPSIAVVE-SELVAEYITTERTDEGTEVAFPLLVSH 855 + V P+ T SPE + + + S E +TT + TE P + Sbjct: 7123 PLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTA 7182 Query: 856 RSQPQQPSQPQRTLLQHVAQSQTATQTS-VVVKSIPASSPGAIT--HIMQQALSSHTAFT 912 S + PS + +A S+T+ TS + + S + AI+ H ++ + + + Sbjct: 7183 ASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESIS 7242 Query: 913 KHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCF 972 S +L VE ++ L S ++ ++ + S + T+ Sbjct: 7243 SLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPE 7302 Query: 973 QTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQL 1032 + ++ I + L + +++I+ Q P ++ D T ++ Sbjct: 7303 ISTTRKIIKFPTSPI---LAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHS--- 7356 Query: 1033 PTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPAS-SEKQTASQ 1091 T+ + P + + L + +P+ P + + P SQ+SL A S +S Sbjct: 7357 -TMTQRLPHSEITTLVSRGAGDVPRPSSLPVE-----ETSPPSSQLSLSAMISPSPVSST 7410 Query: 1092 VEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSP----VTSISPIQASEKTAVS 1147 + + +SVT + G+ T++ S+ P+ +SP TS+ + SE T + Sbjct: 7411 LPASSHSSSASVTSLLTPGQ--VKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDT 7468 Query: 1148 DILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPS-THMVVAGMANSTPQQQK 1206 + + A + P L S T ++ + + M ++ TP Sbjct: 7469 EKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSN 7528 Query: 1207 CRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIP 1266 R+ S P+ SSLTTR +R + ++ + + A ++ + Sbjct: 7529 TRKIQSEPA---SSLTTR-------------LRETSTSEETSLATEANTVLSKV------ 7566 Query: 1267 CHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSS 1318 S+ E S ++ + E++ M QDI GT P S SS Sbjct: 7567 ---STGATTEVSRTEAISFSRTSMSGPEQSTMSQDISI----GTIPRISASS 7611 Score = 80.5 bits (197), Expect = 1e-14 Identities = 223/1180 (18%), Positives = 438/1180 (37%), Gaps = 154/1180 (13%) Query: 149 TTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK----- 203 TT+T TS PV S P ++ AS+V+ PS + +VS S + Sbjct: 2212 TTNTETSIPVNSAG-----PPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHF 2266 Query: 204 -RRRTNSSSSSPVVLKEVPKAVVPV------SKTITVPVSGSPKMSNIMQSIANSLPPHM 256 + T+S + + E+ V P+ S T P SP ++ + S P Sbjct: 2267 PEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTT 2326 Query: 257 SPVKIT--FTKPSTQTT-NTTTQKVIIV------------TTSPSSTFVPNILSKSHNYA 301 SP+ +T FT+ ST + N TT K + ++S S +I S + + Sbjct: 2327 SPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVT 2386 Query: 302 AVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVT--AVVSST 359 + PTS+ T P + ++ + + ++++ +++++PS NT ++ + V T Sbjct: 2387 KTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGT 2446 Query: 360 PSVVMS-TVAQGVSTSAIKMASTR-LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQ 417 PS + T+ V TS+ +A +R + + ++VS T ++P V Sbjct: 2447 PSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDT--------ASGENPTSSNSVV-- 2496 Query: 418 QTQQQVAQPSPVSHQQQPQQSPLPP-GIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT 476 + P+P + + LP G T + ++ ++P+ ++A Sbjct: 2497 -----TSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAH--SLLASTIEPATAFTPHLSAA 2549 Query: 477 LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536 + T S++ +S +++TT + T T PT S + +ATP + V TS Sbjct: 2550 VVTGSSA-----TSEASLLTTSESKAIHSSPQTPTTPT-SGANWETSATPESLLVVTETS 2603 Query: 537 GSII--------TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKG 588 + + T++ +++T K S+ +SG + T +P T + + T+ Sbjct: 2604 DTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFP-TLLPDTPAIPLTATEPTSSLA 2662 Query: 589 TTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAIL--TATRP------ITKMIVTQPKG 640 T+ P + + L E T+ T A++ T + P IT VT+ Sbjct: 2663 TSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPL 2722 Query: 641 IGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPV-TFQATVVSEQTRQLVTETLQQASRVA 699 S+ P+ + P Y +G V + P T + V S+ + T L +S Sbjct: 2723 HPSSTSPSKIVAPRNTTY--EGSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGL 2780 Query: 700 E--------------AGNSSIQEGKE---------------EPQNYTDSSSSSTESSQSS 730 E A + I+ G P T S +T ++ Sbjct: 2781 ERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTAT 2840 Query: 731 QDSQPV-VHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS-----ATSTIK----ALL 780 Q + P + V + + ++ +SP+ + +++ + +T T + L Sbjct: 2841 QSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSL 2900 Query: 781 ELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTER 840 + + ++ +S P D S + + + EK +P + + ++ + + +T Sbjct: 2901 DTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEK--NPRARMMTSTKAISASSFQSTGF 2958 Query: 841 TDEGTEVAFPLLVSHRSQ-PQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITH 899 T+ A P + H + P + R + ++ + +S + + AS +T Sbjct: 2959 TETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASK---LTT 3015 Query: 900 IMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPL 959 + ++ + + L TE +E L P +++L S +Q L Sbjct: 3016 LFSTGQAARSGSSSSPISLSTE----KETSFLSPTASTSRKTSLFLGPSMARQPNILVHL 3071 Query: 960 EQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQ 1019 + + L + Q++ L + Q +I ++ T + + P Sbjct: 3072 QTSALTLSPTSTLNMSQEEPPELTSSQ-----------TIAEEEGTTAETQTLTFTPSET 3120 Query: 1020 HTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMS 1079 T V+ + P+T ++V L + I + Q Q + Sbjct: 3121 PTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNST 3180 Query: 1080 LPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQ 1139 PA +E+ +S + S T ++P +I +P T++ P++ Sbjct: 3181 WPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTV-PME 3239 Query: 1140 ASEKTAVSDILKMSLMEAQIDTNVEHMI--VDPPKKALATSMLTGEAGSL-PSTHMVVAG 1196 T V + S T++ H+ P K+ +ML E SL PS Sbjct: 3240 ----TTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTN 3295 Query: 1197 MANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQ 1236 + + TP R+S ++ S+V T + ++ TGQ Sbjct: 3296 LYSGTP--GGTRQSLATMSSVSLESPTAR----SITGTGQ 3329 Score = 77.4 bits (189), Expect = 8e-14 Identities = 265/1346 (19%), Positives = 471/1346 (34%), Gaps = 161/1346 (11%) Query: 77 TTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAET 136 TT + + SS SI G P ++P+ + A+ + +A + +P +T Sbjct: 6979 TTAEVSRTEVTSSGRTSIPG----PSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQT 7034 Query: 137 GSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSD 196 G + ++ T + + S T + P S + ++ G + S S + Sbjct: 7035 GPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPH--SEMTTLMSRGPGDMSWQSSPSLEN 7092 Query: 197 EDEKPR--KRRRTNS----SSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 P T S SS+ PV + P +PV+ +T + M + + Sbjct: 7093 PSSLPSLLSLPATTSPPPISSTLPVTISSSP---LPVTSLLTSSPVTTTDMLHTSPELVT 7149 Query: 251 SLPP---HMSPVKITFTKPSTQT------TNTTTQKVIIVTT---SPSSTFVPNILSKSH 298 S PP H S ++T K +T T TNT V I ++ SPSS + SK+ Sbjct: 7150 SSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKAT 7209 Query: 299 NYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS----SSGSSSSTPSPIPNTVAVTA 354 + +T + +A +T + S+ S S +GSS T S I + ++ Sbjct: 7210 SPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSE 7269 Query: 355 V-VSSTPSVVMSTVAQGVSTSAIKMA-STRLP---SPKSLVSAPTQ-ILAQFPK---QHQ 405 V + +T + + V TS A ST LP + + ++ PT ILA+ + + Q Sbjct: 7270 VSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQ 7329 Query: 406 QSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSP--------------LP-PGIKPTIQI 450 SP + ++H Q+ P +P P P + Sbjct: 7330 TSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEET 7389 Query: 451 KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSS---NGAIMTTKLVTTPTGTQ 507 S ++ + PS PV++TLP SS+S V+S G + TT+ V + Sbjct: 7390 SPPSSQLSLSAMISPS-----PVSSTLPASSHSSSASVTSLLTPGQVKTTE-VLDASAEP 7443 Query: 508 ATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK-SLATLGGKIISSNIVSGTTTK 566 T + P++S + + AT T + T V K ++ G + SS + TTK Sbjct: 7444 ETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTK 7503 Query: 567 IT----TIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT----------TLLNAGGEKTI 612 T TI + +V + IQ P ++ T T L + Sbjct: 7504 ATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVL 7563 Query: 613 QTVPTGAKPAI---------LTATRPITKMIVTQPKGIGSTVQPAAKIIPTK----IVYG 659 V TGA + T+ + ++Q IG+ + +A + T+ + Sbjct: 7564 SKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTESAKMTITT 7623 Query: 660 QQGKTQVLIKPKPVTFQATVVS-EQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTD 718 Q G ++ ++ AT S +T +V + G P + Sbjct: 7624 QTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKE 7683 Query: 719 SSSSSTESSQSSQDS-QPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSES----QSAT 773 +S S+ S + S PV + ++ TS D+ S S++ Sbjct: 7684 TSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSS 7743 Query: 774 STIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRH-------SPESPSIAV 826 S++ + TT K+ ++ P+ + V + K SP + + Sbjct: 7744 SSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTM 7803 Query: 827 VESELVAE---YITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTS 883 ++ ++ ++ T R TE+A L R T + V T+ Sbjct: 7804 GDTSVLTSTPAFLETRRIQ--TELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATT 7861 Query: 884 VVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSAL 943 + K S PG + +S+ T + + TE E+ P ++ Sbjct: 7862 EISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTST 7921 Query: 944 TQSQSAKQQKLSQPPLEQ--TQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRH 1001 + S ++ + Q + Q+ TL + + + + L K P S+ Sbjct: 7922 LDTSSTTSLTMTHSTISQGFSHSQMSTL---MRRGPEDVSWMSPPLLEK--TRPSFSLMS 7976 Query: 1002 QKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLA---VKTTQQLPKL 1058 T P P V T LP ++ P V +L KTT L K Sbjct: 7977 SPAT------TSPSP-VSST----------LPESISSSPLPVTSLLTSGLAKTTDMLHK- 8018 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 ++P + + + A+SE T ++ P + +VT + + + Sbjct: 8019 ---SSEPVTNSPANLSSTSVEILATSEVTTDTEKTHP--SSNRTVTDVGTSSSGHESTSF 8073 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 + S K+TSP+ S + E T+VS ++I T + L Sbjct: 8074 VLADSQTSKVTSPMVITSTM---EDTSVSTSTPGFFETSRIQTEPTSSL------TLGLR 8124 Query: 1179 MLTGEAGSLPSTHM--VVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQ 1236 + G+ +T M V++G+ + E SS T S + P T Sbjct: 8125 KTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTETIT 8184 Query: 1237 FMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEET 1296 + ++ + AE I Q P + P + + + +E ++ +Q+ E Sbjct: 8185 RLPTSSIMTESAE---MMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEM 8241 Query: 1297 AMEQDIDSSTEDGTEPSPSQSSAERS 1322 S G PSQSS E + Sbjct: 8242 TTL----VSRSPGDMLWPSQSSVEET 8263 Score = 76.6 bits (187), Expect = 1e-13 Identities = 266/1326 (20%), Positives = 472/1326 (35%), Gaps = 189/1326 (14%) Query: 21 RKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIA 80 RK++ E + + + LR T E+ L E + VLS + EV R E ++ Sbjct: 7530 RKIQSEPASSLTTRLRETS--TSEETSLATEANTVLSKVSTGATTEVSRT---EAISFSR 7584 Query: 81 HNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKE 140 +MSGP S+ + + +PR+ A++ + +A + + +TG E Sbjct: 7585 TSMSGPEQST---MSQDISIGTIPRIS------------ASSVLTESAKMTITTQTGPSE 7629 Query: 141 VVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSG----STVYVKSVSCSD 196 S + + T + V + SI P P S + P G S +VK S Sbjct: 7630 STLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTS-MGRGPGGVSWPSPPFVKET--SP 7686 Query: 197 EDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVS------------GSPKMSNI 244 T+ S L +P + +PV+ +T + G+ S++ Sbjct: 7687 PSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSL 7746 Query: 245 MQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVT 304 + L + PST T T + TTS ++L+ S + Sbjct: 7747 STTSHERLTTYKDTAHTEAVHPSTNTGGTN-----VATTSSGYKSQSSVLADSSPMCTTS 7801 Query: 305 KLVPTSVIAST-----TQKPPVVITAS------QSSLVSNSSSGSSSSTPSPIPNTVAVT 353 + TSV+ ST T++ + +S +SS +SSG+ ST T A T Sbjct: 7802 TMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATT 7861 Query: 354 AV----VSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPK 409 + V+S P ST++ +ST + ST +S + Q + Sbjct: 7862 EISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTST 7921 Query: 410 QQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP----GIKPTIQIKQESGVKIITQQVQP 465 T SH Q P + P + K +++ P Sbjct: 7922 LDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMS---SP 7978 Query: 466 SKILPKPVTATLPTS-SNSPIMVVS--SNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRM 522 + P PV++TLP S S+SP+ V S ++G TT ++ + S S+ + Sbjct: 7979 ATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEIL 8038 Query: 523 AATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITT--IPMTSKPNVIV 580 A + KT S TV ++ G + S + T+K+T+ + ++ + V Sbjct: 8039 ATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSV 8098 Query: 581 VQKTTG--KGTTIQGLPGKNVVTTLLNAGGEK----------TIQTVPTGAKPAILTATR 628 T G + + IQ P ++ L + + VPTGA + + Sbjct: 8099 STSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEV--SRT 8156 Query: 629 PITKMIVTQPKGIGS-TVQPAAKI-----IPTKIVYGQQGKTQVLIKPKP---------- 672 +T T G TV P +PT + + + + + P Sbjct: 8157 EVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHT 8216 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNS------SIQEGKEEPQNYTDSSSSSTES 726 V T +T VT+ + S Q EE SS+SS S Sbjct: 8217 VDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEE-----TSSASSLLS 8271 Query: 727 SQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQD---VSSE-SQSATSTIKALLEL 782 ++ PV + S ++ +I D +S E S+TS + + Sbjct: 8272 LPATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHE 8331 Query: 783 QQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTD 842 + TT+++ ++++ QP+ + AV T H +S ++ E+ + T T Sbjct: 8332 RLTTLEDTVDTEDMQPS---THTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTM 8388 Query: 843 EGTEVAF---PLLVSHRSQPQQPSQPQRTLLQHVAQSQ---TATQTSVVVKSIPASSPGA 896 T V+ + R Q +P+ + L+ + S+ +AT+ S V+ +P+ GA Sbjct: 8389 GETSVSISTSDFFETSRIQ-IEPTSSLTSGLRETSSSERISSATEGSTVLSEVPS---GA 8444 Query: 897 ITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQS-QSAKQQKLS 955 T + + + S ++ + G ++ + + + T L +T+S +SA + Sbjct: 8445 TTEVSRTEVIS----SRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETG 8500 Query: 956 QP--PLEQTQLQVKTLQCFQTKQKQTI-----HLQADQLQHKLP-QMPQLSIRHQKLTPL 1007 P E T + F + T H + L + P +P S+ P Sbjct: 8501 SPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSL------PS 8554 Query: 1008 QQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLA---VKTTQQLPKLQQAPNQ 1064 +E + + + LP ++ P V +L VKTT L + ++ Sbjct: 8555 VEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDML----RTSSE 8610 Query: 1065 PKIYVQPQTPQSQMSLPASSE-----KQTASQVEQPIITQGSSVTK-----------ITF 1108 P+ P + + A+SE ++ P++ G+ + K +T Sbjct: 8611 PETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTT 8670 Query: 1109 EGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIV 1168 + P T G +SV TS + T + L L E I T+ E Sbjct: 8671 KPTSPMATTSTLGNTSVS------TSTPAFPETMMTQPTSSLTSGLRE--ISTSQETSSA 8722 Query: 1169 DPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDP 1228 + A + M TG + T + G STP + ST+ ++T I Sbjct: 8723 -TERSASLSGMPTGATTKVSRTEALSLG-RTSTPG--------PAQSTISPEISTETITR 8772 Query: 1229 PAVPAT 1234 + P T Sbjct: 8773 ISTPLT 8778 Score = 76.3 bits (186), Expect = 2e-13 Identities = 195/968 (20%), Positives = 344/968 (35%), Gaps = 209/968 (21%) Query: 76 LTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNA--SLPVP 133 + T+ + S P++++ W I +P + + P F + V++ A H A S +P Sbjct: 10583 IQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNF-FHSELDTVSSTATSHGADVSSAIP 10641 Query: 134 AETGSKEVVCYSYTSTTS-TPTSTPVPSGSIATVKSPRPASPASNVVVLPS--GSTV--Y 188 E+ + T S T TST P+ KSP + + P+ ST+ Sbjct: 10642 TNISPSELDALTPLVTISGTDTSTTFPT----LTKSPHETETRTTWLTHPAETSSTIPRT 10697 Query: 189 VKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSI 248 + + S + D P + +SS + + V SP +++ S Sbjct: 10698 IPNFSHHESDATPSIATSPGAETSSAIPIMTV-----------------SPGAEDLVTS- 10739 Query: 249 ANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSK--SHNYAAVTKL 306 Q T++ T + + + T S P ++ +H A + Sbjct: 10740 --------------------QVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSA 10779 Query: 307 VPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV---------- 356 +PTS I+ + ++T+ +SL + +S+ + + T SP V+ V Sbjct: 10780 IPTSTISPAVSR---LVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVP 10836 Query: 357 -----------SSTPSVVMSTVAQGVSTSAIKMASTRLP--------SPKSLVSAPTQIL 397 +TPS+ S A+ S ST +P S ++++S IL Sbjct: 10837 WTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPIL 10896 Query: 398 AQFPKQHQQSPKQQLYQVQQQTQQQVAQPSP-------------VSHQQQPQQSPLP--- 441 P + + +P ++ + A P+P V+ + + +P Sbjct: 10897 TLSPGEPETTPSMATSHGEEASS---AIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILT 10953 Query: 442 ---------PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 P + + + S V + +V P + ++ TS+ P + +S G Sbjct: 10954 FSLGEPETTPSMATSHGTEAGSAVPTVLPEV-PGMVTSLVASSRAVTSTTLPTLTLSP-G 11011 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSI--------------------------GRMAATP 526 TT + T G +A+ T PTVSP + G + TP Sbjct: 11012 EPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTP 11071 Query: 527 GAATYVKTTSGSII---TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIV--- 580 AT + S + TV P + + SS V+ TT I T+ +S+P Sbjct: 11072 SMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTL-SSSEPETTPSMA 11130 Query: 581 ----VQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPT----GAKPAILTA--TRPI 630 V+ ++ T +PG +VT+L+ + T T+PT +P T+ T Sbjct: 11131 TSHGVEASSAVLTVSPEVPG--MVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSE 11188 Query: 631 TKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQ-----VLIKPKPVTFQATVVSEQTR 685 KMI P V P + + T +V +T + +P T + V T Sbjct: 11189 AKMISAIPT---LAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTE 11245 Query: 686 -------------------QLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTES 726 LVT + +S + S + + T +S + S Sbjct: 11246 ASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRT-TSRFSHSELDTMPSTVTSPEAESS 11304 Query: 727 SQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLE--LQQ 784 S S P + + + S +I+ T PT+ SE+ ++ T A+ + + Sbjct: 11305 SAISTTISPGIPGVLTSLVTSSGRDIS-ATFPTVPESPHESEATASWVTHPAVTSTTVPR 11363 Query: 785 TTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEG 844 TT P+I S A SP+ P ++V +T+ TD Sbjct: 11364 TTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVP-------DMVTSQVTSSGTD-- 11414 Query: 845 TEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQA 904 T + P L +P+ T + S+ T TS + ++P SPGA + Sbjct: 11415 TSITIPTLTLSSGEPE-------TTTSFITYSE--THTSSAIPTLPV-SPGASKMLTSLV 11464 Query: 905 LSSHTAFT 912 +SS T T Sbjct: 11465 ISSGTDST 11472 Score = 74.3 bits (181), Expect = 7e-13 Identities = 190/841 (22%), Positives = 331/841 (39%), Gaps = 156/841 (18%) Query: 54 KVLSISTE-RHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAF 112 K+L+ S + + E+ ++N E T + N SG S S + P+ Q Sbjct: 5103 KILATSKDSKDTKEIFPSINTEE-TNVKANNSGHESHSPALADSET-----PKATTQMVI 5156 Query: 113 TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTS--TPVPSGSIATVKSPR 170 T T A + S+PV GS E T+ PT TP + + +S Sbjct: 5157 TTTVGDPAPST-----SMPVH---GSSET-----TNIKREPTYFLTPRLRETSTSQESSF 5203 Query: 171 PASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKT 230 P + + +P+G+ V S T +SSS + + K+ VP T Sbjct: 5204 PTDTSFLLSKVPTGTITEVSS---------------TGVNSSSKISTPDHDKSTVPPD-T 5247 Query: 231 ITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFV 290 T I + +S+ + + IT T+ S + + + + +T+ S Sbjct: 5248 FT---------GEIPRVFTSSIKTKSAEMTIT-TQASPPESASHSTLPLDTSTTLSQGGT 5297 Query: 291 PNILSKSHNYAAVTKLV---PTSVIASTTQKPPVVITASQSSLVSN----SSSGSSSSTP 343 + +++ Y+ VT L+ P +V TT PPV T+S SSL+S+ S S SS++P Sbjct: 5298 HSTVTQGFPYSEVTTLMGMGPGNVSWMTT--PPVEETSSVSSLMSSPAMTSPSPVSSTSP 5355 Query: 344 -----SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILA 398 SP+P T T+V+ +T V+ +T + V++S ++S P A + A Sbjct: 5356 QSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERP-----ATYKDTA 5410 Query: 399 QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKI 458 S + V +Q S ++ + + +PL T ++ V Sbjct: 5411 HTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPL----MSTTSTLGDTSVST 5466 Query: 459 ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPS 518 T + + + T PT+S SP + SS ++ TT T T +Y PT Sbjct: 5467 STPNISQTNQIQ-----TEPTASLSPRLRESSTSEKTSS---TTETNTAFSYV-PT---- 5513 Query: 519 IGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIP-MTSKPN 577 GA T T I+ S++ L I+ +I +G T++ T P MT Sbjct: 5514 --------GAITQASRTE---ISSSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAE 5562 Query: 578 VIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI----------------------QTV 615 + V +TT G T QG+ + TTL G T+ T Sbjct: 5563 MTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTT 5622 Query: 616 PTGAKPA--------ILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVL 667 P + + +T+ P++ T P+ I S+ P ++ + +V T VL Sbjct: 5623 PPVEETSSGFSLMSPSMTSPSPVSS---TSPESIPSSPLPVTALLTSVLV----TTTNVL 5675 Query: 668 --IKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 P+PVT +S T++ +T A EA ++S+ +T+++ ++ Sbjct: 5676 GTTSPEPVTSSPPNLSSPTQERLTTYKDTAH--TEAMHASM---------HTNTAVANVG 5724 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSS--ESQSATSTIKALLE-L 782 +S S +SQ V + + S I T + + E++ T + +L+ L Sbjct: 5725 TSISGHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGL 5784 Query: 783 QQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRH----SPESPSIAVVESELVAEYITT 838 + T E++ + T+ LS+ VP T E + +I+ + ++ YI+T Sbjct: 5785 RDTRTSEEINTVTETSTV-LSE--VPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYIST 5841 Query: 839 E 839 E Sbjct: 5842 E 5842 Score = 73.9 bits (180), Expect = 9e-13 Identities = 274/1358 (20%), Positives = 489/1358 (36%), Gaps = 228/1358 (16%) Query: 109 QTAFTVTANAVANAAIQHNAS--------LPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 Q FT+ ++ A+ H+A+ + P G ++V S S T + + S Sbjct: 8799 QGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVS 8858 Query: 161 GSIATVKSPRPASPASNVVVLPSGST-----VYVKSVSCSDEDEKPRKRRRTNSSSSSPV 215 S T SP ++P+ + P T V +K+ D +P T S S + Sbjct: 8859 LSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPV----TTSPPSMNI 8914 Query: 216 VLKEVPKAVVPVSKTITVPVSGSPKMSNI-----MQSIANSLPPHMSPVKITFTKPSTQT 270 E +T + +S + ++ + Q +S P P K+T + Sbjct: 8915 TSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVT-----SPV 8969 Query: 271 TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL 330 ++T K I+ TT P+S+ + I +S + L PT ST+Q+ + +A++ S Sbjct: 8970 VTSSTIKDIVSTTIPASSEITRIEMES-----TSTLTPTPRETSTSQE---IHSATKPST 9021 Query: 331 VSNSSSGSSSSTPSPIPNTVAVTAVVSST--PSVVMSTVAQGVSTSAIKMASTR-LPSPK 387 V + S++ S +T V+SS+ PS ST++Q +ST I ST + + Sbjct: 9022 VPYKALTSATIEDS-------MTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTES 9074 Query: 388 SLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPT 447 + ++ TQ + T +Q SH Q PG P Sbjct: 9075 TEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQG--FSHSQMTALMSRTPGDVPW 9132 Query: 448 IQ---IKQESGVKIITQQVQPSKILPKPVTATLPTSSNS---PIMVVSSNGAIMTTKLVT 501 + +++ S P PV++TLP S +S P+ + ++G + TT+L+ Sbjct: 9133 LSHPSVEEASSASFSLSS--PVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLG 9190 Query: 502 TPTGTQATYTRPTVSPSIGRMAATPGAATYVK-------TTSG----SIITVVPKSLATL 550 T + + T + P +S + + A T + TSG S +V+ S+ T Sbjct: 9191 TSSEPE-TSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTK 9249 Query: 551 GGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEK 610 + +G T +T+ P S + I +T K + GL ++ +A + Sbjct: 9250 ATSSMGITYPTGDTNVLTSTPAFSDTSRI---QTKSKLSLTPGLMETSISEETSSATEKS 9306 Query: 611 TI-QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI-----IPTKIVYGQQGKT 664 T+ +VPTGA + + T I+ + P ST+ + I T + ++ T Sbjct: 9307 TVLSSVPTGATTEV-SRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLT--RKEST 9363 Query: 665 QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724 + I PK AT T TL +S + G S + T S Sbjct: 9364 DMAITPKTGPSGATSQG-------TFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGP 9416 Query: 725 E-----SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKAL 779 E S S + + P +++S + TSP+ +Y S S S+ + +L Sbjct: 9417 EDVSWPSPLSVEKNSPPSSLVSS----------SSVTSPSPLYSTPSGSSHSSPVPVTSL 9466 Query: 780 LELQQTTVKEKLESKPRQPTIDLSQMAVPI-QMTQEKRHSPESPSIAVVESELVAEYITT 838 + L++ T M + + + + E+ +I V E+ + TT Sbjct: 9467 FTSIMMKATDMLDASLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETT 9526 Query: 839 ERTDE----------GTEVAFPLLVSHRSQPQQPS--------------QPQRTLLQHVA 874 T+E T+V P++ S + S + +L + Sbjct: 9527 SATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLR 9586 Query: 875 QSQTA------TQTSVVVKSIPA-----------------SSPGAITHIMQQALSSHTAF 911 +++T+ T+TS V+ +P+ S PG M +S Sbjct: 9587 ETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVT 9646 Query: 912 TKHSEELGTEEGEVEEMDTLDPQTGLFYRSA------------LTQSQSAKQQKLSQPPL 959 + + TE E+ T+ QTG ++ L+ + S Q LS Sbjct: 9647 RLSTSPIMTESAEI----TITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHS-- 9700 Query: 960 EQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMP-QLSIRHQKLTPLQQEQAQPKPDV 1018 E T L + + + + + + L +P S+ T L + P P Sbjct: 9701 EMTNLMSRGPESLSWTSPRFV--ETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVT 9758 Query: 1019 QHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLP----------KLQQAPNQP--K 1066 +V L T + P+T T+ ++P K+ + N K Sbjct: 9759 SLILPGLVKTTEVLDT--SSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAK 9816 Query: 1067 IYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITF-----EGRQPPT--VTKI 1119 + +S S+ A SE T + I + T T E R+ PT + Sbjct: 9817 VRTSSSVHESHSSVLADSET-TITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSL 9875 Query: 1120 TGGSSVPKLTSPVTSIS---------PIQASEKTAVSDILK----------MSLMEAQID 1160 T G + TSI+ P A+ + ++++I+ S M I Sbjct: 9876 TPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDII 9935 Query: 1161 TNVEHMIVDPPKKALATSM-LTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGS 1219 T V + + +T M +T + S +T +A +T + S P + S Sbjct: 9936 TEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTH-STVPPRFLHS 9994 Query: 1220 SLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSG 1279 +TT P P+ + ++ + + ++P P SS+ PS Sbjct: 9995 EMTTLMSRSPENPSWKSSLFVEKTSSSSS--------LLSLPVTTSPSVSSTLPQSIPSS 10046 Query: 1280 LLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQS 1317 + + + M + D+STE GT SP+ S Sbjct: 10047 SFSVTSLLTP-------GMVKTTDTSTEPGTSLSPNLS 10077 Score = 70.5 bits (171), Expect = 1e-11 Identities = 185/928 (19%), Positives = 327/928 (35%), Gaps = 116/928 (12%) Query: 22 KLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAH 81 ++++E + + S LR + E+ E S VLS EV R E +++ Sbjct: 8405 RIQIEPTSSLTSGLRETS--SSERISSATEGSTVLSEVPSGATTEVSRT---EVISSRGT 8459 Query: 82 NMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEV 141 +MSGP+ +++I + RL T+ +T +A + I+ + T + + Sbjct: 8460 SMSGPD---QFTISPDISTEAITRL--STSPIMTESAESAITIETGSPGATSEGTLTLDT 8514 Query: 142 VCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKP 201 ++ S T + S + T+ S P +P S V+ S Sbjct: 8515 STTTFWSGTHSTASPGFSHSEMTTLMSRTPGD-------VPWPSLPSVEEASSVSSSLSS 8567 Query: 202 RKRRRTNSSSSSPVVLKEVPKAVV------PVSKTITVPVSGSPKMS---NIMQSIANSL 252 T+ S+ P + P V PV T + S P+ S N+ + A L Sbjct: 8568 PAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEIL 8627 Query: 253 PPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK-LVPTSV 311 PS+ T VI SPSS + +K + A T L TSV Sbjct: 8628 ATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSV 8687 Query: 312 IASTTQKPPVVITASQSSLVSN------------------SSSGSSSSTPSPIPNTVAVT 353 ST P ++T SSL S S SG + + + T A++ Sbjct: 8688 STSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALS 8747 Query: 354 AVVSSTPSVVMSTVAQGVSTSAIKMASTRL------------------PSPKSLVSAPTQ 395 +STP ST++ +ST I ST L S + + T Sbjct: 8748 LGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTS 8807 Query: 396 ILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESG 455 A +P H + + + +P+S + P P ++ T Sbjct: 8808 SRASWPGTHSAATHRSPHS---------GMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVS 8858 Query: 456 VKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTV 515 + +T P P+ +T SS+S + V+S + T ++ T + T Sbjct: 8859 LSAVTS--------PSPLYSTPSESSHSSPLRVTS---LFTPVMMKTTDMLDTSLEPVTT 8907 Query: 516 SPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSK 575 SP + + AT T I + + T G I + + +P SK Sbjct: 8908 SPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISAR---QEFYSSYPGLPEPSK 8964 Query: 576 PNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP--TGAKPAILTATRPITKM 633 VV +T K +P + +T + T+ P T I +AT+P T Sbjct: 8965 VTSPVVTSSTIKDIVSTTIPASSEITR-IEMESTSTLTPTPRETSTSQEIHSATKPST-- 9021 Query: 634 IVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQ 693 V +T++ + T+++ +G + P T + +E +L T ++ Sbjct: 9022 -VPYKALTSATIEDSM----TQVMSSSRGPS-----PDQSTMSQDISTEVITRLSTSPIK 9071 Query: 694 QASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIA 753 S + G T +S++ S S SQ H + + ++ Sbjct: 9072 TESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVP 9131 Query: 754 METSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQ 813 + P++ ++ SS S S +S + +T+ + + S T L+ V Sbjct: 9132 WLSHPSV--EEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELL 9189 Query: 814 EKRHSPES---PSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLL 870 PE+ P+++ +E++A TE T + ++ +V+ + PS Sbjct: 9190 GTSSEPETSSPPNLSSTSAEILA---ITEVTTDTEKLEMTNVVTSGYTHESPSSV----- 9241 Query: 871 QHVAQSQTATQTSVVVKSIPASSPGAIT 898 +A S T TS + + P +T Sbjct: 9242 --LADSVTTKATSSMGITYPTGDTNVLT 9267 Score = 68.9 bits (167), Expect = 3e-11 Identities = 237/1248 (18%), Positives = 455/1248 (36%), Gaps = 234/1248 (18%) Query: 31 VISALRAQGDLTK---EKKDLLGELSKVLSISTERHRAEVRRAVNDERLT--TIAHNMSG 85 V + + A ++T+ E L + S S E H A V + LT TI +M+ Sbjct: 8979 VSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQ 9038 Query: 86 PNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYS 145 SSS R P + + V + + + + +TGS Sbjct: 9039 VMSSS------RGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATS-- 9090 Query: 146 YTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRR 205 T + TST SG+ +T S + ++ G ++ S + Sbjct: 9091 -RGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLS 9149 Query: 206 RTNSSSSSPV---VLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262 +SSSPV + + + +PV+ +T + + ++ S PP++S Sbjct: 9150 SPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAE 9209 Query: 263 FTKPSTQTTNTTTQKVIIVTTS------PSSTFVPNILSKSHNYAAVTKLV-PTSVIAST 315 + TT+T ++ V TS PSS ++ +K+ + +T T+V+ ST Sbjct: 9210 ILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLTST 9269 Query: 316 TQ---------KPPVVITAS--QSSLVSNSSSGSSSST---------PSPIPNTVAVTAV 355 K + +T ++S+ +SS + ST + + T A+++ Sbjct: 9270 PAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSS 9329 Query: 356 VSSTPSVVMSTVAQGVSTSAIKMASTRLP---------SPKSLVSAPTQ---------IL 397 +S P ST++ S I ST L +PK+ S T Sbjct: 9330 RTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSST 9389 Query: 398 AQFPKQH----QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQE 453 A +P H Q+ P+ + + + V+ PSP+S ++ S L T Sbjct: 9390 ASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVT------ 9443 Query: 454 SGVKIITQQVQPSKILPKPVTATL----------------PTSSNSPIMVVSSNGAIMTT 497 S + + S P PVT+ P ++++P M ++S+ ++ + Sbjct: 9444 SPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPNMNITSDESLAAS 9503 Query: 498 KLVTTPTG------TQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLG 551 K T T A++ T S + +++PG + K S + + Sbjct: 9504 KATTETEAIHVFENTAASHVE-TTSATEELYSSSPGFSEPTKVISPVVTS---------- 9552 Query: 552 GKIISSNIVSGT---TTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGG 608 I N+VS T ++ IT I + S ++ + T T Q + +T+L Sbjct: 9553 -SSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRET---RTSQDITSSTETSTVL---- 9604 Query: 609 EKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLI 668 +P+GA P + T+++ + I Q + + V + + ++ Sbjct: 9605 ----YKMPSGATPEVSR-----TEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMT 9655 Query: 669 KPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQ 728 + +T VT L + +S++ +G ++++ ++ + + Sbjct: 9656 ESAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGL----SHSEMTNLMSRGPE 9711 Query: 729 SSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL--ELQQTT 786 S + P + + R S + + TS + + + S S+ + +L+ L +TT Sbjct: 9712 SLSWTSP--RFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTT 9769 Query: 787 VKEKLESKPR---QPTIDLSQMAVP----IQMTQEKRHSPESPSIAVVE-SELVAEYITT 838 S+P+ P + + + +P I EK H + ++A V S V E ++ Sbjct: 9770 EVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSS 9829 Query: 839 ERTDEGTEVAFPLL---------VSHRSQP------QQPSQPQRTLLQHVAQSQTA---- 879 D T + P + S P + P++P +L ++ T+ Sbjct: 9830 VLADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETT 9889 Query: 880 --TQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGL 937 T+TS V+ +P S+ ++ M + +SS+ S++ T+ P Sbjct: 9890 SITETSAVLYGVPTSATTEVS--MTEIMSSNRIHIPDSDQ-----------STMSPD--- 9933 Query: 938 FYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQL 997 +T+ S+ E TQ+ + T + Q+ A Sbjct: 9934 IITEVITRLSSSSMMS------ESTQMTITTQKSSPGATAQSTLTLATTT---------- 9977 Query: 998 SIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPK 1057 PL + + P H++ + TLM++ P+ P Sbjct: 9978 -------APLARTHSTVPPRFLHSE---------MTTLMSRSPEN-------------PS 10008 Query: 1058 LQQAPNQPKIYVQPQTPQSQM-SLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTV 1116 + + ++V+ + S + SLP ++ +S + Q I + SVT + G T Sbjct: 10009 WKSS-----LFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTD 10063 Query: 1117 TKITGGSSV-PKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNV 1163 T G+S+ P L+ TS+ + ASE T +D K+ + TNV Sbjct: 10064 TSTEPGTSLSPNLSG--TSVEILAASEVT--TDTEKIHPSSSMAVTNV 10107 Score = 65.9 bits (159), Expect = 3e-10 Identities = 251/1287 (19%), Positives = 433/1287 (33%), Gaps = 224/1287 (17%) Query: 154 TSTPVPSGSIATVK-----SPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTN 208 TS PS + VK S R SP+ P + V+ +S S D + Sbjct: 3640 TSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDIL------ST 3693 Query: 209 SSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN-SLPPHMSPVKITFTKPS 267 S + S ++VP ++V T +P + + S++ S T T + Sbjct: 3694 SWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSA 3753 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 Q T + + SP+++ +P S H +AVT T +P T+ + Sbjct: 3754 PQGATTPQELTLETMISPATSQLP--FSIGHITSAVTPAAMARSSGVTFSRPDP--TSKK 3809 Query: 328 SSLVSNSSSGSSSSTPSPIPNTVAVTAVV----SSTPSVVMSTVAQ-GVSTSAIKMASTR 382 + S ++S+ P +P + A T V + TP Q ++T A + + Sbjct: 3810 AEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSW 3869 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 KS SAP + + V + T ++V S V L Sbjct: 3870 NEKEKSTPSAPWIT-------------EMMNSVSEDTIKEVTSSSSVLRTLNTLDINLES 3916 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS---------SNSPIMVVSSNGA 493 G + K +I + K P T T+ T+ S+S I S++ Sbjct: 3917 GTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSK 3976 Query: 494 IMTTKLVTTPTGTQATYTRPTVS-PSIGRMAATPGA---------ATYVKTTS------- 536 + T+ +VTT T QA + T + P R P + + Y+ T+S Sbjct: 3977 L-TSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSII 4035 Query: 537 ----GSIITVVPKSLATLGGKIISSNIV---------SGTTTKITTIP-MTSKPNVIVVQ 582 + IT P++ T +I SS + S T+++ P MT +I+ Sbjct: 4036 SSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAM 4095 Query: 583 KTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTVPTGAKPAILTA----TRPITKMIVTQ 637 +T+ G T P + T G T Q K + + T + V + Sbjct: 4096 QTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEE 4155 Query: 638 PKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASR 697 S V A P+ I+ QG + P F ++ET + Sbjct: 4156 TSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVF------------LSET-SGLGK 4202 Query: 698 VAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETS 757 + S++ G P N + ++ + + ++S+D++ + H Sbjct: 4203 TTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSA----------------- 4245 Query: 758 PTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRH 817 D + + ATS+ + + +KP + T L + +T Sbjct: 4246 ------DTAVTNMEATSSEYSPIPGH---------TKPSKATSPLVTSHIMGDITS---- 4286 Query: 818 SPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQ 877 S +V S E T ++G L SQ + T++ HV+ Sbjct: 4287 -----STSVFGSSETTEIETVSSVNQG------LQERSTSQVASSATETSTVITHVSSGD 4335 Query: 878 TATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMD-TLDPQTG 936 T V K+ S G Q ++S FT S T E T+ QTG Sbjct: 4336 ATTH---VTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTITTQTG 4392 Query: 937 LFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQ 996 A TQ + P L +T L V T Q+++ I + P Sbjct: 4393 P--TGAATQGPYLLDTS-TMPYLTETPLAV-TPDFMQSEKTTLISKGPKDVSWTSPPSVA 4448 Query: 997 LSIRHQKLTPLQQEQAQPKPDV---QHTQHPMVAKD--------------------RQLP 1033 + LTP P QHT P+ A P Sbjct: 4449 ETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSP 4508 Query: 1034 TLMAQPPQTVVQVLAVKTTQQL--PKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQ 1091 + P ++ LA T + P + +A S +LP SSE TA+ Sbjct: 4509 QNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHS--TLPVSSEPSTATS 4566 Query: 1092 VEQPIITQGSSVTKITFEGRQPPTV-----TKITGG----SSVPKLTSPVTSISPIQASE 1142 P + G ++ I+ G + + + +T G S++ ++ S S + Sbjct: 4567 PMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVS 4626 Query: 1143 KTAVSDILKM---------------SLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSL 1187 A+++ KM S I + + + P ++T M T + GS Sbjct: 4627 VGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSS 4686 Query: 1188 PSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQ-- 1245 +T + + ST S +PS V KI T +++V Q Sbjct: 4687 GATSKIPLALDTST-----LETSAGTPSVVTEGFAHSKI------TTAMNNDVKDVSQTN 4735 Query: 1246 ------KKAEESPAEIIIQAIPQ---YAIPCHSSSNVVVEPSGLLELNNFTSQQLD---D 1293 + S A +++ +P + HS+S+ V S L T+ ++D + Sbjct: 4736 PPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLE 4795 Query: 1294 EETAMEQDIDSSTEDGTEPSPSQSSAE 1320 T+ Q + ++ +D + S + + E Sbjct: 4796 TVTSSPQSMSNTLDDISVTSAATTDIE 4822 Score = 64.7 bits (156), Expect = 6e-10 Identities = 215/1096 (19%), Positives = 385/1096 (35%), Gaps = 155/1096 (14%) Query: 207 TNSSSSSPVVLKEVPK-AVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265 T+S + VL +VP A +SK + G P S I I+ S + T+ Sbjct: 7842 TSSGTKMSTVLSKVPTGATTEISKEDVTSIPG-PAQSTISPDISTRTVSWFSTSPV-MTE 7899 Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325 + T NT T + T S+ + S + ++ +++ S +++ ++ P ++ Sbjct: 7900 SAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSW 7959 Query: 326 SQSSLVSNS----SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381 L+ + S SS +T SP P + + +SS+P V S + G++ + + + Sbjct: 7960 MSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKS 8019 Query: 382 RLP---SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQS 438 P SP +L S +ILA + + P S++ Sbjct: 8020 SEPVTNSPANLSSTSVEILA-----------------TSEVTTDTEKTHPSSNRTVTDVG 8062 Query: 439 PLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTK 498 G + T + +S +T P +T+T+ +S S S+ G T++ Sbjct: 8063 TSSSGHESTSFVLADSQTSKVTS--------PMVITSTMEDTSVS----TSTPGFFETSR 8110 Query: 499 LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG-----SIITVVPKSLATLGGK 553 + T PT + R T S S G AT + +G S V S ++ G Sbjct: 8111 IQTEPTSSLTLGLRKT-SSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGF 8169 Query: 554 IISSNIVSGTTTKITTIP----MTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +T IT +P MT +++ +T G+T + ++ TT Sbjct: 8170 AQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTT------P 8223 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIK 669 ++T T +T ++M + G + P+ + Sbjct: 8224 NWVETHST------VTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTS 8277 Query: 670 PKPVTFQATVVSE-QTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST---- 724 P PV+ +T+V + + L +L V I EP + S+ SST Sbjct: 8278 PSPVS--STLVEDFPSASLPVTSLLNPGLVITTDRMGI---SREPGTSSTSNLSSTSHER 8332 Query: 725 ----ESSQSSQDSQPVVH-VIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKAL 779 E + ++D QP H + + R S HE S + + D SE+ ATS + Sbjct: 8333 LTTLEDTVDTEDMQPSTHTAVTNVRTSISGHE-----SQSSVLSD--SETPKATSPMGTT 8385 Query: 780 LELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSI-AVVESELVAEYITT 838 + +T+V I + + +T R + S I + E V + + Sbjct: 8386 YTMGETSVSISTSDFFETSRIQIEPTS---SLTSGLRETSSSERISSATEGSTVLSEVPS 8442 Query: 839 ERTDEGTEVAFPLLVSHR----SQPQQ---PSQPQRTLLQHVAQSQTATQTSVVVKSIPA 891 T TEV+ ++S R S P Q + ++ S T+++ +I Sbjct: 8443 GAT---TEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIET 8499 Query: 892 SSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQT-GLFYRSAL--TQSQS 948 SPGA + +S T F + + EM TL +T G +L + S Sbjct: 8500 GSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEAS 8559 Query: 949 AKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQ 1008 + LS P + T F T L P L++ K T + Sbjct: 8560 SVSSSLSSPAMTSTSF-------FST-------LPESISSSPHPVTALLTLGPVKTTDML 8605 Query: 1009 QEQAQPK----PDVQHTQHPMVA-----KDRQ------------LPTLM---AQPPQTVV 1044 + ++P+ P++ T ++A KDR+ + T++ P + Sbjct: 8606 RTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLA 8665 Query: 1045 QVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVT 1104 ++ K T + N P P++ M+ P SS ++ T ++ Sbjct: 8666 DLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATER 8725 Query: 1105 KITFEGRQPPTVTKI--TGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTN 1162 + G TK+ T S+ + ++P P Q++ +S + T Sbjct: 8726 SASLSGMPTGATTKVSRTEALSLGRTSTP----GPAQSTISPEISTETITRISTPLTTTG 8781 Query: 1163 VEHMIVDPPKKALATS------MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPST 1216 M + P S + T S P TH + + +P P Sbjct: 8782 SAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTH---SAATHRSPHSGMTTPMSRGPED 8838 Query: 1217 VG--SSLTTRKIDPPA 1230 V S + K PP+ Sbjct: 8839 VSWPSRPSVEKTSPPS 8854 Score = 63.2 bits (152), Expect = 2e-09 Identities = 189/949 (19%), Positives = 330/949 (34%), Gaps = 152/949 (16%) Query: 76 LTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAE 135 +T H++S S +I ++P + + A T A++ + + + P + Sbjct: 10255 VTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGD 10314 Query: 136 TGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCS 195 T S P+STPVP S + PA + + S +T Y S Sbjct: 10315 ATLS-------TIAESLPSSTPVPFSSSTFTTTDSSTIPALHEIT-SSSATPYRVDTSLG 10366 Query: 196 DEDEKPRKR----------RRTNSSSSSPVVLKEVPKAVV--PVSKTITVPVSGS--PKM 241 E R + +SSSP++ + ++V V+ VP + + Sbjct: 10367 TESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRT 10426 Query: 242 SNIMQSIA-------------------NSLPP------HMSPVKITFTKPSTQTTNTTTQ 276 IM+ I S P H K T + T TT Sbjct: 10427 DGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTAL 10486 Query: 277 KVIIVTTSPSSTFVPNI--LSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQS---SLV 331 K T +S + P + L+ + + +PT ++ +T P V + S SL Sbjct: 10487 KTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLG 10546 Query: 332 SNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVS 391 + +S+ +TPS TA + S S V Q + S+ + +T S V Sbjct: 10547 AETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTT-----ASWVI 10601 Query: 392 APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQ-----PSPVSHQQQPQQSPL------ 440 P + + K +L V A P+ +S + +PL Sbjct: 10602 HPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGT 10661 Query: 441 -PPGIKPTI---QIKQESGVKIITQQVQPSKILPK-------------PVTATLP---TS 480 PT+ + E+ +T + S +P+ P AT P TS Sbjct: 10662 DTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETS 10721 Query: 481 SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII 540 S PIM VS + T VT+ +GT T PT++ S G T+ + + S I Sbjct: 10722 SAIPIMTVSPGAEDLVTSQVTS-SGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAI 10780 Query: 541 TVVPKSLATLGGKIISSNIVS-GTTTKITTIPMTSKPN--VIVVQKTTGKGTTIQGLP-- 595 +++ ++++S + S T T +T+ P V T T +P Sbjct: 10781 PT--STISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWT 10838 Query: 596 -------GKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPA 648 + ++ + G ++ VPT P + T + +VT + + ST P Sbjct: 10839 TSIFFHSKSDTTPSMTTSHGAESSSAVPT---PTVSTEVPGVVTPLVTSSRAVISTTIPI 10895 Query: 649 AKIIP-----TKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGN 703 + P T + G+ P P + V LVT + S Sbjct: 10896 LTLSPGEPETTPSMATSHGEEASSAIPTPTV--SPGVPGVVTSLVTSSRAVTSTTIPILT 10953 Query: 704 SSIQEGKEEPQNYTDSSSSSTESSQSSQDSQP--VVHVIASRRQDWSEHEIAM------- 754 S+ E + P T + + + + P V ++AS R S + Sbjct: 10954 FSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEP 11013 Query: 755 ETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLES-----KPRQPTIDLSQMAVPI 809 ET+P++ +S A+ST+ + V + S PT+ LS + Sbjct: 11014 ETTPSM----ATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELET 11069 Query: 810 QMTQEKRHSPE------SPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQ-QP 862 + H E +P+++ S +V +T+ R T + P+L S+P+ P Sbjct: 11070 TPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTI--PILTLSSSEPETTP 11127 Query: 863 SQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIM--QQALSSHT 909 S + + S V ++ PG +T ++ +A++S T Sbjct: 11128 SM----------ATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTT 11166 Score = 62.0 bits (149), Expect = 4e-09 Identities = 184/891 (20%), Positives = 328/891 (36%), Gaps = 130/891 (14%) Query: 65 AEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTA-FTVTANAVANAA 123 +++ A+N++ N + +S S + LV +P V T + T++ V+ ++ Sbjct: 4718 SKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSS 4777 Query: 124 IQHNASLPVPAETG-SKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLP 182 + ++ + + S E V S S ++T V S + +++ P+ N VV Sbjct: 4778 VLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSI---NTVVTN 4834 Query: 183 SGSTVYV----KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGS 238 G+T +VS E K T S+ + + +PK+ S + Sbjct: 4835 VGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLT 4894 Query: 239 PKM--SNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSK 296 PK+ ++I Q I +S T T P + T TT+ TS SST P Sbjct: 4895 PKLRETSISQEITSSTE--------TSTVPYKELTGATTEVSRTDVTSSSSTSFPG---- 4942 Query: 297 SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356 + + V+ + T + P + +A + G++S +T + Sbjct: 4943 -PDQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGPHGATSQ------DTFTMDPSN 4995 Query: 357 SSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQ 416 ++ + + S + G S + +R+P S S P+ P SP Sbjct: 4996 TTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMT----- 5050 Query: 417 QQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT 476 T ++ P P S L G+ VKI + +++ +PVT++ Sbjct: 5051 --TPSLISSTLPEDKLSSPMTSLLTSGL-----------VKIT--DILRTRL--EPVTSS 5093 Query: 477 LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536 LP S++ +++++ TK + T+ T + S A + T TT Sbjct: 5094 LPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQ 5153 Query: 537 GSIITVV----PKSLATLGGKIISSNIVSGTTTKIT-------TIPMTSKP---NVIVVQ 582 I T V P + + G ++NI T +T T +S P + ++ + Sbjct: 5154 MVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSK 5213 Query: 583 KTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP----TGAKPAILTA---TRPITKMIV 635 TG T + G N + + +K+ TVP TG P + T+ T+ I Sbjct: 5214 VPTGTITEVSS-TGVNSSSKISTPDHDKS--TVPPDTFTGEIPRVFTSSIKTKSAEMTIT 5270 Query: 636 TQ---PKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATV-------VSEQTR 685 TQ P+ + P + T Q G + + P + T+ VS T Sbjct: 5271 TQASPPESASHSTLP----LDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTT 5326 Query: 686 QLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQ 745 V ET SS+ P + S SST PV Sbjct: 5327 PPVEET------------SSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVT-------- 5366 Query: 746 DWSEHEIAMETSPTIIYQDV--SSESQSATST---IKALLELQQTTVKEKLESKPRQPTI 800 A+ TS + DV ++ +S TS+ + ++ + T K+ ++ Sbjct: 5367 -------ALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMH-- 5417 Query: 801 DLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPL-LVSHRSQP 859 + AV T H +S +A E+ ++T T T V+ +S +Q Sbjct: 5418 HSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQI 5477 Query: 860 QQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASS---PGAITHIMQQALSS 907 Q ++P +L + +S T+ +TS ++ A S GAIT + +SS Sbjct: 5478 Q--TEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISS 5526 Score = 62.0 bits (149), Expect = 4e-09 Identities = 234/1213 (19%), Positives = 406/1213 (33%), Gaps = 185/1213 (15%) Query: 129 SLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS----GSIAT----------VKSPRPASP 174 S PVP + YS S +S ++ PV S G T V S P++ Sbjct: 5928 SSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSAS 5987 Query: 175 ASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSS--SPVVLKEVPKAVVPVSKT-- 230 + + +L S ++ +++ S E+ TNS S V + P P T Sbjct: 5988 SFSGEILTSEASTNTETIHFS-ENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGS 6046 Query: 231 ------ITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTS 284 ++ GSP+ N+ + + L P + ST +NT V + + Sbjct: 6047 MMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAAT 6106 Query: 285 PSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPS 344 S A VT PT + AS +++S +S +S S S++P Sbjct: 6107 EVSR------------AEVTYYDPTFMPASAQ--------STKSPDISPEASSSHSNSP- 6145 Query: 345 PIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404 P+ + T + PS V S + TS I S PS ++ Sbjct: 6146 PLTISTHKTIATQTGPSGVTSLGQLTLDTSTIA-TSAGTPSART---------------- 6188 Query: 405 QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQ---PQQSPL-----PPGIKPTIQIKQESGV 456 Q + V V + SP S ++ Q+PL P + T+Q S + Sbjct: 6189 QDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSL 6248 Query: 457 KIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVS 516 +T +P P A + T ++ + V+ + + L T+ +AT T+ Sbjct: 6249 VSVTS-------VPTPTLAKI-TDMDTNLEPVTRSPQNLRNTLATS----EATTDTHTMH 6296 Query: 517 PSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKP 576 PSI A G + + + TV P S + SG + T++P +S Sbjct: 6297 PSINTAVANVGTTS---SPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAM 6353 Query: 577 NVIVVQKTTG------KGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI 630 I + T + +T Q + + +T+ +K T LT++ Sbjct: 6354 KKIESETTFSLIFRLRETSTSQKIGSSSDTSTVF----DKAFTAATTEVSRTELTSSSRT 6409 Query: 631 TKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP--------VTFQATVVSE 682 + +P T + ++ T + + + + P +T+ ++ + Sbjct: 6410 SIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTS 6469 Query: 683 Q--TRQLVTETLQQ------ASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQ 734 Q T +T Q SRV E G P SSSSS S + Sbjct: 6470 QAGTHSAMTHGFSQLDLSTLTSRVPE-----YISGTSPPSVEKTSSSSSLLSLPAITSPS 6524 Query: 735 PVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESK 794 PV + R H ++ TS + D+ + S + + TT ++ +++ Sbjct: 6525 PVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTE 6584 Query: 795 PRQPTIDLSQMAVPIQMTQEKRHS--PESPSIAVVESELVAEY----------------I 836 P+ +++ V ++++ +S P V S +V + I Sbjct: 6585 KMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEI 6644 Query: 837 TTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGA 896 T + +A L + SQ S + +L + T T + V S S PG Sbjct: 6645 TRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGP 6704 Query: 897 ITHIMQQALSSH-----------------TAFTKHSEELGTEEGEVEEMDTLDPQ----- 934 +S+ T T+ LG+ +DT Sbjct: 6705 DHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGT 6764 Query: 935 ----TGLFYRSALTQSQSAKQQKLS---QPPLEQTQLQ-------VKTLQCFQTKQKQTI 980 T F S +T + + LS P +E+T T + +TI Sbjct: 6765 HSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTI 6824 Query: 981 HLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPP 1040 H + L P L + L + P++ T H ++ D + A P Sbjct: 6825 HTTPSPMTSLLT--PSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHP 6882 Query: 1041 QTVVQVLAVKTTQQLPKLQQ---APNQPKIYVQPQTPQSQM-------SLPASSEKQTAS 1090 T V+TT Q A ++ P S M S+ SSE Sbjct: 6883 STSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIK 6942 Query: 1091 QVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDIL 1150 + +T G T I+ + T T I S VP T+ S + + +S +T++ Sbjct: 6943 RESTYSLTPGLRETSIS-QNASFSTDTSIV-LSEVPTGTTAEVSRTEVTSSGRTSIPGPS 7000 Query: 1151 KMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRES 1210 + +++ + + P A + + G ST + ST + Q S Sbjct: 7001 QSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHS 7060 Query: 1211 CSSPSTVGSSLTT 1223 + S +TT Sbjct: 7061 TLTQRFPHSEMTT 7073 Score = 61.6 bits (148), Expect = 5e-09 Identities = 247/1206 (20%), Positives = 426/1206 (35%), Gaps = 177/1206 (14%) Query: 84 SGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVC 143 S P S +++ PL P L + V + + + + SL E EV Sbjct: 6056 STPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTY 6115 Query: 144 YSYT------STTSTPTSTPVPSGS--------IATVKSPRPASPASNVVVL-------- 181 Y T +T +P +P S S I+T K+ + S V L Sbjct: 6116 YDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTS 6175 Query: 182 --------PSGST---VYVKSVSCSDED------EKPRKRRRTNS-SSSSPVVLKEVPKA 223 PS T V ++ S + D P NS SS +P+++ P Sbjct: 6176 TIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSP 6235 Query: 224 VV------PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTT--- 274 V S ++V +P ++ I N P SP + T +++ T T Sbjct: 6236 VTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTM 6295 Query: 275 -----TQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV----IASTTQKPPVVITA 325 T + TTS + F + S Y A + +V TS I ST+ + Sbjct: 6296 HPSINTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKK 6355 Query: 326 SQS----SLV-------SNSSSGSSSSTPSPIPNT-------VAVTAVVSSTPSVVMSTV 367 +S SL+ ++ GSSS T + V+ T + SS+ + + T Sbjct: 6356 IESETTFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTE 6415 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 +S + T L + L + + +A H+ + + L T Q S Sbjct: 6416 KPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHS 6475 Query: 428 PVSH-----QQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS-S 481 ++H S +P I T E + P+ P PV TLP S Sbjct: 6476 AMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRP 6535 Query: 482 NSPIMVVS--SNGAIMTTKLVTT-----PTGTQATYTRPTVSPSI----GRMAATPGAAT 530 +SP+ + S ++G + TT ++ + P ++ PT S I +T A T Sbjct: 6536 SSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVT 6595 Query: 531 YVKTTSGSIITVVPKSLATLGGKIISSNIVS---GTTTKITTIPMTSKPNVIVVQKTTG- 586 V TT+ + + K+ S + S T T++P +S+ I ++ T Sbjct: 6596 NVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSL 6655 Query: 587 ----KGTTIQGLP----GKNVVTTLLNAGGEKTIQTVPTGAK------PAILTATRPI-T 631 KGT+ P K+ V L G +T +T ++ P T + I T Sbjct: 6656 AHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDIST 6715 Query: 632 KMIVTQPKGIGSTVQPAAKIIP-TKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLV-T 689 ++I + P +G T II T G + + + +A S T++ + Sbjct: 6716 EVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHS 6775 Query: 690 ETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSE 749 E ++ E + +I P + +S SS+ + S PV + Sbjct: 6776 EMTTVMNKDPEILSWTI------PPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPS 6829 Query: 750 HEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ----TTVKEKLESKPRQPTIDLSQM 805 ++ T ++ D S T++ L TT ++ + P+ + Sbjct: 6830 PMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAAT 6889 Query: 806 AVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQ--PQQPS 863 V T H +S +A E + T T T V+ + VS + ++ + Sbjct: 6890 NVE---TTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKREST 6946 Query: 864 QPQRTLLQHVAQSQTA---TQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGT 920 L+ + SQ A T TS+V+ +P + ++ + S T+ S+ Sbjct: 6947 YSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSR-TEVTSSGRTSIPGPSQSTVL 7005 Query: 921 EEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQP-PLEQTQLQVKTLQCFQTKQKQT 979 E M T LF ++ T ++SA+ +Q P T TL TK + Sbjct: 7006 PEISTRTM------TRLF--ASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAK 7057 Query: 980 IHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQP 1039 H L + P H ++T L ++ D+ P + LP+L++ P Sbjct: 7058 TH---STLTQRFP--------HSEMTTL---MSRGPGDMSWQSSPSLENPSSLPSLLSLP 7103 Query: 1040 ----PQTVVQVLAVK-TTQQLPKLQQAPNQP-----KIYVQPQ-TPQSQMSLPASSEKQ- 1087 P + L V ++ LP + P ++ P+ S L +S+++ Sbjct: 7104 ATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERL 7163 Query: 1088 ------TASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQAS 1141 T ++ P +S +I G + P + S K TSP+ I+ Q Sbjct: 7164 TTGKDTTNTEAVHPSTNTAASNVEIPSSGHESP--SSALADSETSKATSPM-FITSTQED 7220 Query: 1142 EKTAVS 1147 A+S Sbjct: 7221 TTVAIS 7226 Score = 58.9 bits (141), Expect = 3e-08 Identities = 262/1319 (19%), Positives = 453/1319 (34%), Gaps = 205/1319 (15%) Query: 42 TKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVP 101 T +L G ++L+ S E + +T + SG S SI Sbjct: 10070 TSLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKA 10129 Query: 102 LMPRLVPQTAF--TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVP 159 P P + +++ + AN + P T S +++ TPT+TP Sbjct: 10130 TYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSS 10189 Query: 160 SGSIATVKSPRPA------------SPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 GS ++S + PAS +P + E + Sbjct: 10190 PGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPES 10249 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHM-----SPVKIT 262 + S + ++P ++TI+ + P +S M S A + P SP T Sbjct: 10250 RFTMSVTESTHHLSTDLLPSAETISTG-TVMPSLSEAMTSFATTGVPRAISGSGSPFSRT 10308 Query: 263 FTKPSTQTTNTTTQKVIIVTTSP--SSTFVPN------ILSKSHNYAAVTKLVPTSV--I 312 + P T +T + + T P SSTF L + + +A V TS+ Sbjct: 10309 ESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTE 10368 Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 +STT+ V++ S+L ++S G +SS SPI +T T SV + TV S Sbjct: 10369 SSTTEGRLVMV----STLDTSSQPGRTSS--SPILDT-------RMTESVELGTV---TS 10412 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + STRL ++ T+I + + P + QT A P + Sbjct: 10413 AYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVK-----GPQTSTSPASPKGLHTG 10467 Query: 433 QQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSN 491 + +K T +K S + T P+ P+ A++ +S P ++ + Sbjct: 10468 GTKRMETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITT 10527 Query: 492 GAIM-----TTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + TT + T G + + P +PS+ + A+ + + SG+ + V ++ Sbjct: 10528 PYVFPDVPETTSSLATSLGAETSTALPRTTPSVFNRESETTAS--LVSRSGAERSPVIQT 10585 Query: 547 LATLGGKIISSNIVSGTTTKITTIPMTSK--PNVI------VVQKTTGKGTTIQGLPGKN 598 L + S TIP SK PN V T G + N Sbjct: 10586 LDVSSSE--PDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTN 10643 Query: 599 V-------VTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651 + +T L+ G T T PT K T TR +T P ST+ + Sbjct: 10644 ISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTW---LTHPAETSSTI---PRT 10697 Query: 652 IPTKIVYGQQGKTQVLIKPKPVTFQA---TVVSEQTRQLVTETLQQASRVAEAGNSSIQE 708 IP + + P T A VS LVT S+V +G Sbjct: 10698 IPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVT------SQVTSSG------ 10745 Query: 709 GKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSE 768 TD + + + S + + + ++ H A +TS I +S Sbjct: 10746 --------TDRNMTIPTLTLSPGEPKTIASLVT--------HPEA-QTSSAIPTSTISPA 10788 Query: 769 SQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQE---------KRHSP 819 +++ L + +T L + P +P +S + P Q + S Sbjct: 10789 VSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSD 10848 Query: 820 ESPSIAVVE-SELVAEYITTERTDEGTEVAFPLLVSHRS-----------QPQQPSQPQR 867 +PS+ +E + T + E V PL+ S R+ P +P Sbjct: 10849 TTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPS 10908 Query: 868 TLLQHVAQSQTATQTSVVVKSIP------ASSPGAITH----IMQQALSSHTAFTKHSEE 917 H ++ +A T V +P +S A+T I+ +L + Sbjct: 10909 MATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATS 10968 Query: 918 LGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQK 977 GTE G + T+ P+ S + S++ L P L + + +T T Sbjct: 10969 HGTEAGSA--VPTVLPEVPGMVTSLVASSRAVTSTTL--PTLTLSPGEPETTPSMATSHG 11024 Query: 978 QTIHLQADQLQHKLP----------------QMPQLSIRHQKL--TP-------LQQEQA 1012 + ++P +P L + +L TP + A Sbjct: 11025 AEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSA 11084 Query: 1013 QP----KPDVQHTQHPMVAKDRQLP-------TLMAQPPQTVVQVLAVKTTQQLPKLQQA 1061 P P V P+V R + TL + P+T + + Sbjct: 11085 VPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVE-------- 11136 Query: 1062 PNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKIT---FEGRQPPTVTK 1118 + + V P+ P SL SS T++ + P +T S + T + ++ Sbjct: 11137 ASSAVLTVSPEVPGMVTSLVTSSRAVTSTTI--PTLTISSDEPETTTSLVTHSEAKMISA 11194 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 I + P + VTS+ SE +A S++ S ID+ V H + + Sbjct: 11195 IPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLT 11254 Query: 1179 MLTGEAGSLPSTHMVVA---GMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPAT 1234 + TGE P T++ + ++ST + R S S T+ S++T+ + + + +T Sbjct: 11255 VSTGE----PFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAIST 11309 Score = 56.6 bits (135), Expect = 2e-07 Identities = 226/1128 (20%), Positives = 393/1128 (34%), Gaps = 138/1128 (12%) Query: 84 SGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVC 143 S + +S W+ E P+ T + T+ ++ + S+ P T VV Sbjct: 511 SSTSKASSWTSESTAQQFSEPQ---HTQWVETSPSMKTERPPASTSVAAPITTSVPSVVS 567 Query: 144 YSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK 203 T TS+ + S T+ A P ++ +P+G ++ S + + Sbjct: 568 GFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLL 627 Query: 204 RRRTNSSSSS---PVVLKEVPKAVVP-VSKT-------------ITVPVSGSPKMSNIMQ 246 R T SS +S + VP +V P VSKT T+ S P+ S++ Sbjct: 628 TRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQS 687 Query: 247 SI-----------ANSLPPHMSPV--KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNI 293 S N+ P SP TK ST ++ V+ S +STF Sbjct: 688 SAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTF---- 743 Query: 294 LSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSST-----PSPIPN 348 SH+ A + T I++ T+ V+++ S + S ++T PSP Sbjct: 744 ---SHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGE 800 Query: 349 TVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVS---APTQILAQFPKQHQ 405 A + + ST S + T + S+ PS SL S T + P H Sbjct: 801 ETAGSVLTLST-SAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHL 859 Query: 406 QSPKQQLYQVQQQTQQQVAQP-SPVSHQQQPQQS-PLPPGIKPTIQIKQESGVKIITQQV 463 + + + ++ + V+QP + VS + S +P + PT+ + + + Sbjct: 860 FTSGE---ETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHL 916 Query: 464 QPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMA 523 V+ TSS S V +S G+ + T T T + R T + S + Sbjct: 917 ---------VSELRATSSTS---VTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQS 964 Query: 524 AT-PGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTT------------TKITTI 570 T P + KT S T V S +L ++ S S T T I T Sbjct: 965 TTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTT 1024 Query: 571 PMTSKPNVIVVQKTT---GKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTAT 627 T+ P + V T GKG +G + + A E ++ T AK ++ + Sbjct: 1025 ETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDF--TMAKESVSMSV 1082 Query: 628 RPITKMIVTQPKGIGSTVQ-------PAAKIIPTKIVYGQQGKTQVLI---------KPK 671 P M G T Q + +I + G + L P Sbjct: 1083 SPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPD 1142 Query: 672 PVTFQAT----VVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESS 727 P + ++T + S + T+ S I + E + + S+T + Sbjct: 1143 PGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLT 1202 Query: 728 QSSQDSQPVVHVIASRRQDWSEHEIAMETS----PTIIYQDVSSESQS------ATSTIK 777 S+ + + D ++E S PT+ S+ + S A+S Sbjct: 1203 PSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESP 1262 Query: 778 ALLELQQTTVKEKLESKPRQ-PTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELV---A 833 + ++L +V + P P+I+ +M SPE + + Sbjct: 1263 STIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPT 1322 Query: 834 EYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASS 893 YITT + + S R+ + P+ A S + +S + PA+ Sbjct: 1323 TYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATK 1382 Query: 894 PGAITHIMQQALSSHTAFTKHSE-----ELGTEEGEVEEMDTLDPQTGLFYRSALTQSQS 948 IT + + H +TK +E E + G V + P G S L + Sbjct: 1383 AWTITDTTEHSTQLH--YTKLAEKSSGFETQSAPGPVSVVIPTSPTIG---SSTLELTSD 1437 Query: 949 AKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQ 1008 + L P EQT + + T + + + M +I TP Sbjct: 1438 VPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTP-S 1496 Query: 1009 QEQAQPKPD---VQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKT--TQQLPKLQQAPN 1063 E ++ + D +++T + + + +L T V + + T T + QA + Sbjct: 1497 HELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQD 1556 Query: 1064 QPKIYVQP----QTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKIT 1107 + P Q+ + Q S+PAS+ ++V + TQG S ++ T Sbjct: 1557 TLSATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEAT 1604 Score = 56.2 bits (134), Expect = 2e-07 Identities = 219/1103 (19%), Positives = 385/1103 (34%), Gaps = 178/1103 (16%) Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI--AT 165 P VT A++A +++LPV +E ST TS VP+ S+ A Sbjct: 4533 PSINKAVTNMGTASSAHVLHSTLPVSSEP--------------STATSPMVPASSMGDAL 4578 Query: 166 VKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV 225 P S +++ P+ S + + + ++ S+ S + E K V Sbjct: 4579 ASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEV 4638 Query: 226 PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNT-TTQKVIIV--- 281 P +P + S+A+S + P+ I+ +TQT ++ T K+ + Sbjct: 4639 PSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDT 4698 Query: 282 TTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSS 341 +T +S P+++++ ++ +T + V + PP AS S S + Sbjct: 4699 STLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEAS-------SPSSQAPV 4751 Query: 342 TPSPIPNTVAVTAVVSSTPS-VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQF 400 + +P++VA T ST S V MS+V +++S +K A S +++ S+P Sbjct: 4752 LVTTLPSSVAFTPQWHSTSSPVSMSSV---LTSSLVKTAGKVDTSLETVTSSP------- 4801 Query: 401 PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIIT 460 Q T ++ S + + P I + +G + Sbjct: 4802 -------------QSMSNTLDDISVTSAATTDIETTH----PSINTVVTNVGTTGSAFES 4844 Query: 461 QQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIG 520 + P+P T P VTT +T T+S SI Sbjct: 4845 HSTVSA--YPEPSKVTSPN--------------------VTT-----STMEDTTISRSIP 4877 Query: 521 RMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIV 580 + + T T +TTS ++ PK T IS I S T T +T+P Sbjct: 4878 KSSKT--TRTETETTS----SLTPKLRET----SISQEITSSTET--STVPYKELTGATT 4925 Query: 581 -VQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPK 639 V +T ++ PG + T L+ E T TR T I+T+ Sbjct: 4926 EVSRTDVTSSSSTSFPGPDQSTVSLDISTE---------------TNTRLSTSPIMTESA 4970 Query: 640 GIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL----VTETLQQA 695 I T Q +G + + P T QA + S T VT + + Sbjct: 4971 EITITTQTGP--------HGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRI 5022 Query: 696 SRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSS-----QDSQPVVHVIASRRQDWSEH 750 + + + P ++ S + +T S SS + S P+ ++ S Sbjct: 5023 PQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGL------ 5076 Query: 751 EIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQ 810 + + + V+S + +ST +L T K+ ++K P+I+ + V Sbjct: 5077 -VKITDILRTRLEPVTSSLPNFSSTSDKIL----ATSKDSKDTKEIFPSINTEETNVKAN 5131 Query: 811 MTQEKRHSPESPSIAVVESE----LVAEYITTERTDEGTEVAFPLLVSHRSQ--PQQPSQ 864 + + HSP A+ +SE ITT D + P+ S + ++P+ Sbjct: 5132 NSGHESHSP-----ALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTY 5186 Query: 865 PQRTLLQHVAQSQTA---TQTSVVVKSIPASSPGAITHIMQQALSSHTAFT-----KHSE 916 L+ + SQ + T TS ++ +P G IT + ++S + + K + Sbjct: 5187 FLTPRLRETSTSQESSFPTDTSFLLSKVPT---GTITEVSSTGVNSSSKISTPDHDKSTV 5243 Query: 917 ELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE------QTQLQVKTLQ 970 T GE+ + T +T + TQ+ + S PL+ Q Q Sbjct: 5244 PPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQ 5303 Query: 971 CFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDR 1030 F + T+ + P ++ L A P + P Sbjct: 5304 GFPYSEVTTLMGMGPGNVSWMTTPPVEET--SSVSSLMSSPAMTSPSPVSSTSPQSIPSS 5361 Query: 1031 QLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKI-YVQPQTPQSQMSLPASSEKQTA 1089 LP V + TT PN I + +P T + A+ T Sbjct: 5362 PLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTN 5421 Query: 1090 SQVEQPIITQG------SSVTKITFEGRQPP--TVTKITGGSSVPKLTSPVTSISPIQAS 1141 + V + T G SSV + + P + T G +SV T ++ + IQ Sbjct: 5422 TAVTN-VGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTE 5480 Query: 1142 EKTAVSDILKMSLMEAQIDTNVE 1164 ++S L+ S + + E Sbjct: 5481 PTASLSPRLRESSTSEKTSSTTE 5503 Score = 54.3 bits (129), Expect = 8e-07 Identities = 213/1185 (17%), Positives = 425/1185 (35%), Gaps = 173/1185 (14%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAE-TGSKEVVCYSYTSTTSTPTSTPVPSGS 162 P VP A T + + ++ P P + T S+++ T +++P T + Sbjct: 9019 PSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMT 9078 Query: 163 IATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPK 222 I T ++ P + + + L + +T + S + + + S + V P Sbjct: 9079 ITT-QTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPS 9137 Query: 223 AVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVT 282 S + ++ S + ++ +S+ PV T +TT +++ + Sbjct: 9138 VEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTT-----ELLGTS 9192 Query: 283 TSPSSTFVPNILSKSHNYAAVT-------KLVPTSVIAST-TQKPPVVITASQSSLVSNS 334 + P ++ PN+ S S A+T KL T+V+ S T + P + A + + S Sbjct: 9193 SEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATS 9252 Query: 335 SSGSSSSTPSPIPNTVAVTAVVSSTP---------------------------------- 360 S G + T T V++STP Sbjct: 9253 SMGITYPTGD--------TNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATE 9304 Query: 361 -SVVMSTVAQGVS-----TSAIKMASTRLPSP-KSLVSAPTQI----------------- 396 S V+S+V G + T AI + T +P P +S +S+ T + Sbjct: 9305 KSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTD 9364 Query: 397 LAQFPKQHQQ-SPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESG 455 +A PK + Q + + + + Q+ PQ P + + S Sbjct: 9365 MAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSP 9424 Query: 456 VKIITQQVQPSKILPKPVTATLP-------TSSNSPIMVVSSNGAIM--TTKLVTT---P 503 + + S + VT+ P +S +SP+ V S +IM T ++ P Sbjct: 9425 LSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEP 9484 Query: 504 TGTQATYTRPTVSPSIGRMAATP----------GAATYVKTTSGSIITVVPKSLATLGGK 553 T A T S+ AT AA++V+TTS + + K Sbjct: 9485 ETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTK 9544 Query: 554 IISSNIVSGT---TTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEK 610 +IS + S + TT+P +S I ++ + ++ +T+ + Sbjct: 9545 VISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITS--STETST 9602 Query: 611 TIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKP 670 + +P+GA P + T+++ + I Q + + V + + ++ + Sbjct: 9603 VLYKMPSGATPEVSR-----TEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTES 9657 Query: 671 KPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSS 730 +T VT L + +S++ +G ++++ ++ + +S Sbjct: 9658 AEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQG----LSHSEMTNLMSRGPESL 9713 Query: 731 QDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL--ELQQTTVK 788 + P + + R S + + TS + + + S S+ + +L+ L +TT Sbjct: 9714 SWTSP--RFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEV 9771 Query: 789 EKLESKPR---QPTIDLSQMAVP----IQMTQEKRHSPESPSIAVVE-SELVAEYITTER 840 S+P+ P + + + +P I EK H + ++A V S V E ++ Sbjct: 9772 LDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVL 9831 Query: 841 TDEGTEVAFPLL---------VSHRSQP------QQPSQPQRTLLQHVAQSQTA------ 879 D T + P + S P + P++P +L ++ T+ Sbjct: 9832 ADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSI 9891 Query: 880 TQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFY 939 T+TS V+ +P S+ ++ M + +SS+ S++ + E+ T + + Sbjct: 9892 TETSAVLYGVPTSATTEVS--MTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMS 9949 Query: 940 RSALTQSQSAKQQKLSQPPLEQTQLQVKT-----LQCFQTKQKQTIHLQADQLQHKLPQM 994 S + QK S Q+ L + T + T + +H + L + P+ Sbjct: 9950 EST---QMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPEN 10006 Query: 995 PQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQ 1054 P L + + + T P V+ TL P + V ++ T Sbjct: 10007 PSWK---SSLFVEKTSSSSSLLSLPVTTSPSVSS-----TLPQSIPSSSFSVTSL-LTPG 10057 Query: 1055 LPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPP 1114 + K +P + P + + + A+SE T ++ P + +VT + Sbjct: 10058 MVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHP--SSSMAVTNVGTTSSGHE 10115 Query: 1115 TVTKITGGSSVPKLTSPV-TSISPIQASEKTAVSDILKMSLMEAQ 1158 + ++ S K T PV T S + S T++ + + EA+ Sbjct: 10116 LYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPANFETTGFEAE 10160 Score = 52.4 bits (124), Expect = 3e-06 Identities = 113/478 (23%), Positives = 186/478 (38%), Gaps = 55/478 (11%) Query: 63 HRAEVRRAVNDERLTTIAHNMS--GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVA 120 H AE V+ + +H S P+ + ++ R VP +P + V + V Sbjct: 11580 HPAETSTTVSGT-IPNFSHRGSDTAPSMVTSPGVDTRSGVPTTT--IPPSIPGVVTSQVT 11636 Query: 121 NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV 180 ++A + ++P + + S + T T VP I TV S P + AS V Sbjct: 11637 SSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVP---IRTVPSSEPDTMASWVTH 11693 Query: 181 LPSGSTVYVKSVSC---SDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSG 237 P ST ++ S S D P + +SS V+ P A V+ IT S Sbjct: 11694 PPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQIT---SS 11750 Query: 238 SPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKS 297 S + ++ +S P + T P T+T+ T P+ST P + S Sbjct: 11751 GAATSTTVPTLTHS-PGMPETTALLSTHPRTETSKTF----------PASTVFPQV---S 11796 Query: 298 HNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS 357 A++T + P A T+ P T+S +L+ +S S P+ P A TA +S Sbjct: 11797 ETTASLT-IRPG---AETSTALPTQTTSSLFTLLVTGTSRVDLS-PTASPGVSAKTAPLS 11851 Query: 358 STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQ 417 + P ST+ + S + +T L + S T L SP Sbjct: 11852 THPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTL-----TVSPAVSGLSSAS 11906 Query: 418 QTQQQVAQPSPVSHQQQPQQSPL-PPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTA- 475 T + + + + P + + PP T+ +G T + PS++ P T+ Sbjct: 11907 ITTDKPQTVTSWNTETSPSVTSVGPPEFSRTV-----TGT---TMTLIPSEMPTPPKTSH 11958 Query: 476 ---TLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAAT 530 PT+ MV ++N + TT ++PT + T T T++ S+ TPG +T Sbjct: 11959 GEGVSPTTILRTTMVEATN--LATTG--SSPTVAKTTTTFNTLAGSLFTPLTTPGMST 12012 Score = 50.8 bits (120), Expect = 8e-06 Identities = 113/534 (21%), Positives = 192/534 (35%), Gaps = 102/534 (19%) Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSV 192 PAET + S + + T+ PV T P +S S + P S + V Sbjct: 11495 PAETNTMVPRTTPKFSHSKSDTTLPVA----ITSPGPEASSAVSTTTISPDMSDLVTSLV 11550 Query: 193 SCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN-- 250 S T++S++ P L E P + +T P S +S + + ++ Sbjct: 11551 PSSG----------TDTSTTFPT-LSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRG 11599 Query: 251 -----------------SLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNI 293 +P P I S T++ T I T +PS Sbjct: 11600 SDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETT 11659 Query: 294 LSKSHNYAAVT------KLVPTS---VIASTTQKPPVVITASQSSLVSNSSSGSSSSTPS 344 S + + T + VP+S +AS PP S+ VS ++S S S+P Sbjct: 11660 ASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPP-----QTSTPVSRTTSSFSHSSPD 11714 Query: 345 PIPNTVAVTAVVSSTPSVVMSTVAQGVS-------TSAIKMASTRLPSPKSLVSAP--TQ 395 P V T+ + S V++T++ G TS+ ST +P+ P T Sbjct: 11715 ATP--VMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETTA 11772 Query: 396 ILAQFPKQHQQS--PKQQLY-QVQQQTQQQVAQPSPVSHQQQPQQSP------------- 439 +L+ P+ P ++ QV + T +P + P Q+ Sbjct: 11773 LLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSR 11832 Query: 440 --LPPGIKPTIQIKQ---------ESGVKIITQQVQPSKILPKPVTAT---LPTSSNSPI 485 L P P + K E+ I T + + + AT TS+++ Sbjct: 11833 VDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLT 11892 Query: 486 MVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545 + VS + +++ +TT T SPS+ + G + +T +G+ +T++P Sbjct: 11893 LTVSPAVSGLSSASITTDKPQTVTSWNTETSPSV----TSVGPPEFSRTVTGTTMTLIPS 11948 Query: 546 SLAT-----LGGKIISSNIVSGTTTKITTIPMT-SKPNVIVVQKTTGKGTTIQG 593 + T G + + I+ T + T + T S P V KTT T+ G Sbjct: 11949 EMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSP---TVAKTTTTFNTLAG 11999 Score = 45.8 bits (107), Expect = 3e-04 Identities = 222/1201 (18%), Positives = 418/1201 (34%), Gaps = 164/1201 (13%) Query: 132 VPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVL-PSGSTVYVK 190 VP ET + V S + + + + +P+G+ + KSP A+ V L PS + Sbjct: 3236 VPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTN 3295 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTIT-VPVSGSPKMSNIMQSIA 249 S + P R++ ++ SS V L+ P +++IT SP++ + + Sbjct: 3296 LYSGT-----PGGTRQSLATMSS-VSLES------PTARSITGTGQQSSPELVSKTTGME 3343 Query: 250 NSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAV---TKL 306 S+ + T S T++ + + TSP+S V ++ KS + T Sbjct: 3344 FSMWHGSTGGTTGDTHVSLSTSSNILEDPV---TSPNS--VSSLTDKSKHKTETWVSTTA 3398 Query: 307 VPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPI--------PNTVAVTAVVSS 358 +P++V+ + + S S++SS S ++ S I NT+ +T+ + Sbjct: 3399 IPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQT 3458 Query: 359 TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418 T V + + QG+ TS + + S S+ SP L ++ Sbjct: 3459 TSLVSLPSGDQGI-TSLTNPSGGKTSSASSVT----------------SPSIGLETLRAN 3501 Query: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478 + +P + SP E + +T P ++ T+ Sbjct: 3502 VSAVKSDIAPTAGHLSQTSSP------------AEVSILDVTTAPTPG------ISTTIT 3543 Query: 479 TSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGS 538 T + I + N + + + +TP + T + T PS A + T TS Sbjct: 3544 TMGTNSISTTTPNPEVGMSTMDSTPATERRTTS--TEHPSTWSSTAASDSWTVTDMTSNL 3601 Query: 539 IITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKN 598 + P +++T+ TT + S + + G+ T I G + Sbjct: 3602 KVARSPGTISTMH----------------TTSFLASSTELDSMSTPHGRITVI----GTS 3641 Query: 599 VVTTLLNAGGEKT-IQTVPTGAKPAILTATRPIT------KMIVTQPKGIGSTVQPA--- 648 +VT +A KT T P+ TA+ PI+ +M ++ P + ++ P+ Sbjct: 3642 LVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTE 3701 Query: 649 AKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQE 708 A+ +P +V T K P T +T + + L +T + S + +S + Sbjct: 3702 AEDVPVSMVSTDHAST----KTDPNTPLSTFLFDSLSTLDWDTGRSLS--SATATTSAPQ 3755 Query: 709 GKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIA------------SRRQDWSEHEIAMET 756 G PQ T + S +SQ + + SR S+ T Sbjct: 3756 GATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTST 3815 Query: 757 S-PTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEK 815 PT +SA +T+ + +T + + Q + A +++ Sbjct: 3816 QLPTTTSAHPGQVPRSAATTLDVIPHTAKT--PDATFQRQGQTALTTEARATSDSWNEKE 3873 Query: 816 RHSPESPSIAVVESELVAEYITTERTDEGT------EVAFPLLVSHRSQPQQPSQPQRTL 869 + +P +P I + + V+E E T + + L S P S P Sbjct: 3874 KSTPSAPWITEMMNS-VSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSP---- 3928 Query: 870 LQHVAQSQTATQTSVVVKSI-PASSPGAIT---HIMQQALSSHTAFTKHSEEL---GTEE 922 + +A S++ T + S + G +T H + +H+A +K + + T E Sbjct: 3929 YERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTRE 3988 Query: 923 GEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHL 982 + M T + +S A+ + S +E + + T Q I Sbjct: 3989 QAIVSMST----------TTWPESTRARTEPNSFLTIELRDVS-PYMDTSSTTQTSIISS 4037 Query: 983 QADQLQHKLPQMPQLSIRHQKLTPLQQE-QAQPKPDVQHTQ---HPMVAKDRQLPTLMAQ 1038 K P+ S + + L Q ++ P T+ P + + + M Sbjct: 4038 PGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQT 4097 Query: 1039 PPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIIT 1098 P + A T P Q T + +L + + T+ + Sbjct: 4098 SPPGATSLSA--PTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEE 4155 Query: 1099 QGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQ 1158 SS + + P+ +T P T PVTS+ SE + + MS + + Sbjct: 4156 TSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVF---LSETSGLGKTTDMSRISLE 4212 Query: 1159 IDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVG 1218 T++ + +AL+T + + ++ + +T + + PS Sbjct: 4213 PGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKAT 4272 Query: 1219 SSLTTRKIDPPAVPATGQF--------MRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSS 1270 S L T I +T F + +V Q E S +++ A + H S Sbjct: 4273 SPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVS 4332 Query: 1271 S 1271 S Sbjct: 4333 S 4333 Score = 45.1 bits (105), Expect = 5e-04 Identities = 236/1273 (18%), Positives = 443/1273 (34%), Gaps = 220/1273 (17%) Query: 65 AEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAI 124 A +R E+ T + GP +S+ S LVP A T +N + + Sbjct: 4124 ATTQRFTYSEKTTLFS---KGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQG 4180 Query: 125 QHNASLPVPAETGSKEVVCYSYT---STTSTPTSTPVPSGSIATVKSPRPASPAS-NVVV 180 +S P E T S S T +P +T AS + Sbjct: 4181 HSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKA 4240 Query: 181 LPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPK 240 + + V ++ + + P S ++SP+V + + T + V GS + Sbjct: 4241 IHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDI-----TSSTSVFGSSE 4295 Query: 241 MSNI--MQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSH 298 + I + S+ L + ++Q ++ T+ ++T S ++ Sbjct: 4296 TTEIETVSSVNQGLQE----------RSTSQVASSATETSTVITHVSSGDATTHVTKTQA 4345 Query: 299 NYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS 358 +++ T + ++T V T +SL+ SSG V +T Sbjct: 4346 TFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSG------------VTITTQTGP 4393 Query: 359 TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418 T + ST + +P + S T ++++ PK Sbjct: 4394 TGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPK---------------- 4437 Query: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478 V+ SP S + S L P + TI P T+TL Sbjct: 4438 ---DVSWTSPPSVAETSYPSSLTPFLVTTI----------------------PPATSTLQ 4472 Query: 479 ---TSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTT 535 TSS V ++G + TT ++ T + +PS + AT A T ++T Sbjct: 4473 GQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSPQNLNNPS-NEILATLAATTDIETI 4531 Query: 536 SGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLP 595 SI V T G S++++ +T+P++S+P +T + Sbjct: 4532 HPSINKAV-----TNMGTASSAHVLH------STLPVSSEP-------STATSPMVPASS 4573 Query: 596 GKNVVTTLLNAGGEKT-IQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPT 654 + + ++ G E T I+ PT + LTA R + + + ST + + II + Sbjct: 4574 MGDALASISIPGSETTDIEGEPTSS----LTAGRKENSTL----QEMNSTTE--SNIILS 4623 Query: 655 KIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQ 714 + G + + P +F AT + T Q+++ + + + P Sbjct: 4624 NVSVGAITEATKMEVP---SFDATFI---------PTPAQSTKFPDIFSVASSRLSNSPP 4671 Query: 715 NYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATS 774 + ++T++ S S+ +A++TS + E+ + T Sbjct: 4672 MTISTHMTTTQTGSSGAT---------------SKIPLALDTS--------TLETSAGTP 4708 Query: 775 TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAE 834 ++ + + K+ + D+SQ P Q++ SP S + +V Sbjct: 4709 SV-----VTEGFAHSKITTAMNNDVKDVSQTNPPF---QDEASSPSSQAPVLV------- 4753 Query: 835 YITTERTDEGTEVAF-PLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASS 893 T + VAF P S S S +L++ + T+ +T V S P S Sbjct: 4754 ------TTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLET---VTSSPQS- 4803 Query: 894 PGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQK 953 M L + + + ++ T + + T TG + S T S + K Sbjct: 4804 -------MSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSAYPEPSK 4856 Query: 954 LSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ 1013 ++ P + + ++ T+ K +T + + P++ + SI Q++T + Sbjct: 4857 VTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSI-SQEITSSTETSTV 4915 Query: 1014 PKPDVQHTQHPMVAKD--RQLPTLMAQPPQTVVQV-LAVKTTQQLPKLQQAPNQPKIYVQ 1070 P ++ + D T P Q+ V + ++ +T +L +I + Sbjct: 4916 PYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESAEITIT 4975 Query: 1071 PQT----PQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVP 1126 QT SQ + T +T G S +T + P T SV Sbjct: 4976 TQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVD 5035 Query: 1127 KLTSPVTSISPIQASEKTAVSDIL---KMSLMEAQIDTNVEHMIVDPPKKALATSMLTGE 1183 K +SP + +S + + +S L K+S + T+ I D + L +T Sbjct: 5036 KTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRL--EPVTSS 5093 Query: 1184 AGSLPSTHMVVAGMANSTPQQQKCRESCSSPST-VGSSLTTRKIDPPAV------PATGQ 1236 + ST + + + ++ S ++ T V ++ + + PA+ AT Q Sbjct: 5094 LPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQ 5153 Query: 1237 FMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSS---NVVVEPSGLLELNNFTSQQLDD 1293 + VG PA P ++P H SS N+ EP+ F + +L + Sbjct: 5154 MVITTTVG------DPA-------PSTSMPVHGSSETTNIKREPT------YFLTPRLRE 5194 Query: 1294 EETAMEQDIDSST 1306 T+ E + T Sbjct: 5195 TSTSQESSFPTDT 5207 Score = 43.1 bits (100), Expect = 0.002 Identities = 266/1350 (19%), Positives = 461/1350 (34%), Gaps = 244/1350 (18%) Query: 82 NMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEV 141 NM+ SS ++ + L+ P + + + V++ + + GS Sbjct: 1663 NMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPR 1722 Query: 142 VCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKP 201 + + S+ GS + P +SP + V GST + K V+ + Sbjct: 1723 LNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDIS 1782 Query: 202 RKRRRTNSSS---------SSPVVLKE----------VPKAVVPVSKTITVPVSGSPKMS 242 + RT SSS S+ KE P + V+ I++ +S +P Sbjct: 1783 KSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAP--- 1839 Query: 243 NIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAA 302 N S+ S H S T S T T ++ + S T ++ + + + Sbjct: 1840 NTTDSLDLSHGVHTSSAGTLATDRSLNTGVTRASRL----ENGSDTSSKSLSMGNSTHTS 1895 Query: 303 VTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP-- 360 +T + V +S +P ++++L T +P +++T SS P Sbjct: 1896 MTYTEKSEVSSSIHPRPETSAPGAETTL-----------TSTPGNRAISLTLPFSSIPVE 1944 Query: 361 SVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ 420 V+ + + G ++ M + + P + ++ I H S ++ Q Q Sbjct: 1945 EVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPY 2004 Query: 421 -QQVAQPSPVSHQ---------QQPQQSPLPPGIKPTIQIKQ--ESGVKIITQQVQ---- 464 VA + +H+ P S + TI + S + +T + Sbjct: 2005 VNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTW 2064 Query: 465 PSKILPKP-------VTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQ--ATYTRPTV 515 PS L + V+ T++ P+ +S A T G Q A T T Sbjct: 2065 PSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTD 2124 Query: 516 SPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSK 575 + S+ ++ TP A SI + VP +A I S + VSG T++ T+ Sbjct: 2125 ASSVTGLSETPVGA--------SISSEVPLPMA-----ITSRSDVSGLTSE-----STAN 2166 Query: 576 PNVIVVQKTTGKGTTIQGLP-GKNVVTTLLNAGGEKTIQTVPTGAKPAILTATR-PITKM 633 P++ K T LP +++V+ +N + ++P G+ P T T P+ Sbjct: 2167 PSLGTASSAGTKLTRTISLPTSESLVSFRMNK--DPWTVSIPLGSHPTTNTETSIPVNSA 2224 Query: 634 ----IVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLI---KPKPVTFQATVVSEQTRQ 686 + T + T A+ IPT + + T+V P+ T +S T + Sbjct: 2225 GPPGLSTVASDVIDTPSDGAESIPT-VSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHE 2283 Query: 687 LVT-------ETLQQASRVAEAGNS-SIQEGKEEPQNYTDS---------SSSSTESSQS 729 L + + + A G S SI G E + T + ++S TE+S Sbjct: 2284 LTSRVTPIPGDWMSSAMSTKPTGASPSITLG--ERRTITSAAPTTSPIVLTASFTETSTV 2341 Query: 730 SQDSQPVV---HVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTT 786 S D++ V ++ +R+ +E +S +I ++S + T T + T+ Sbjct: 2342 SLDNETTVKTSDILDARKT--NELPSDSSSSSDLINTSIASSTMDVTKT----ASISPTS 2395 Query: 787 VK-EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 + S P + D Q VP T+ ++ SPS++ T D G+ Sbjct: 2396 ISGMTASSSPSLFSSDRPQ--VPTSTTE--TNTATSPSVS----------SNTYSLDGGS 2441 Query: 846 EVAF------PLLVSHRSQPQQP----SQPQRTLLQHV----AQSQTATQTSVVVKSIPA 891 V P ++H + S+P RT V A + T ++ VV S+PA Sbjct: 2442 NVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPA 2501 Query: 892 --------------------SSPGAITH-IMQQALSSHTAFTKH-SEELGTEEGEVEEMD 929 +SP H ++ + TAFT H S + T E Sbjct: 2502 PGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEAS 2561 Query: 930 TL----------DPQTGLFYRSALTQSQSAKQQK-----------LSQPPLEQTQLQVKT 968 L PQT S SA + L+ L + T Sbjct: 2562 LLTTSESKAIHSSPQTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFST 2621 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQL-------------SIRHQKLTPLQQEQAQPK 1015 + +K T L LP P + S L + + Sbjct: 2622 VSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTV 2681 Query: 1016 PDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQ 1075 P+ T D + ++ P +++ + T+ L + P V P+ Sbjct: 2682 PETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTES--PLHPSSTSPSKIVAPRNTT 2739 Query: 1076 SQMSLPASSEKQTASQVEQPIITQGSSVTKIT-----FEGRQPPTVTKITGGSSVPKLTS 1130 + S+ + A + +Q S ++ T G + +V +T GS + Sbjct: 2740 YEGSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSG 2799 Query: 1131 PVTSISPIQASEKTAVSDILKMSLME----AQIDTNVEHMIVDPPKKALATSMLTGEAGS 1186 + S S KT S L M+ E ++I TN K + + E+G Sbjct: 2800 GIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGL 2859 Query: 1187 LPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPP--AVP---ATGQFMRIQ 1241 L TP + SSPS +SLTT PP +P T +F + Sbjct: 2860 L-------------TPV-----SASSSPSKAFASLTTA---PPTWGIPQSTLTFEFSEVP 2898 Query: 1242 NVGQKKAEESPAEIIIQAIPQYAIPCHSSS 1271 ++ K A + IP SSS Sbjct: 2899 SLDTKSASLPTPGQSLNTIPDSDASTASSS 2928 Score = 38.1 bits (87), Expect = 0.056 Identities = 173/813 (21%), Positives = 280/813 (34%), Gaps = 151/813 (18%) Query: 206 RTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265 RT +SS+ KE + T+TV + P + P + + T+ Sbjct: 130 RTRTSSTEGNFTKEAS------TYTLTVETTSGPVTEK-----------YTVPTETSTTE 172 Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325 + T T+ + + TSP TF + SK + P S+ + T +T Sbjct: 173 GDSTETPWDTRYIPVKITSPMKTFADSTASKEN--------APVSMTPAET-----TVTD 219 Query: 326 SQSSLVSNSSSGSSSS-----TPSPIPNTVAVTA--VVSSTPSVVMSTVAQGVSTSAIKM 378 S + +N S G+ S +P PN+ T+ ++ ST S+ G + + Sbjct: 220 SHTPGRTNPSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRIS 279 Query: 379 ASTRLPSPKSLVSAPTQILAQFPKQHQQSP-KQQLYQVQQQTQQQVAQP-----SPVSHQ 432 S L S S++ + F Q SP + + + T A P S Sbjct: 280 TSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETS 339 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS--NSPIMVVSS 490 + +S + P+I KQ + + + +P A S SP + + Sbjct: 340 AERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGT 399 Query: 491 NGAIMTTKLVTTPTGTQATYTRPTVS----PSIGRMAATPGAATYVKTTSGSIITVVPK- 545 + + +TT +T ++ T T + S + TP + S T+VP Sbjct: 400 STSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTL 459 Query: 546 SLATLGGKIISSNIVSGT--TTKITTIPMTS---------KPNVIVVQKTTGKGTTIQGL 594 TL KI S + VS + T ++ T TS + +++ TT + Sbjct: 460 GFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSW 519 Query: 595 PGKNVVTTLLNAGGEKTIQTVP---TGAKPAILTATRPITKMI-----------VTQPKG 640 ++ + ++T P T PA + PIT + + KG Sbjct: 520 TSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKG 579 Query: 641 I------------GSTVQPAAK--IIPTKI-------VYGQQGKTQVLIKPKPVTFQATV 679 I ST P +PT I G QG T +L + AT Sbjct: 580 IWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTR-------ATA 632 Query: 680 VSEQTRQLVTET----LQQASRVAEAGNSSIQEGKEEPQNYTDSSS--SSTESSQSSQDS 733 SE + L T + + V++ S G +P +YT SS T S QSS Sbjct: 633 SSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKP-SYTMVSSVIPETSSLQSSAFR 691 Query: 734 QPVV---------HVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTI---KALLE 781 + H +S D + H + P + V + SATST KA Sbjct: 692 EGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSS 751 Query: 782 LQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKR-HSPESPSIAVVESELVAEYITTER 840 + TT ++ +K + + LS M + T +R + SP T Sbjct: 752 I--TTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSP--------------LTHP 795 Query: 841 TDEGTEVAFPLLVSHRSQPQQPS---QPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAI 897 + G E A +L S S P TL ++S + S+P+ S G Sbjct: 796 SPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTL-------SLPSVS-GVK 847 Query: 898 THIMQQALSSHTAFTKHSEELGTEEGEVEEMDT 930 T S+H FT E T V + +T Sbjct: 848 TTFSSSTPSTH-LFTSGEETEETSNPSVSQPET 879 >gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] Length = 5765 Score = 90.5 bits (223), Expect = 1e-17 Identities = 128/554 (23%), Positives = 194/554 (35%), Gaps = 52/554 (9%) Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSV 192 P T SK S + T+ P T + S AT +P P+S LP +T V ++ Sbjct: 4292 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4351 Query: 193 SCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSL 252 S P + ++ + P S T + + + Sbjct: 4352 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4411 Query: 253 PPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVI 312 S T+ TT TTT T S+ IL++ A VT VPT Sbjct: 4412 ATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT--VPTGST 4469 Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 A+ + T S+ + + SS +TPS P T + ST + +T + Sbjct: 4470 ATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIP 4529 Query: 373 TSAIKMASTRLP---SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429 +S++ TRL +P + +S T + P+ S VA PS Sbjct: 4530 SSSLGTTWTRLSQTTTPTATMSTATP--SSTPETVHTSTVLTATATTTGATGSVATPSST 4587 Query: 430 SHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPV--------TATLPTS 480 PG T ++ + T P L PV T T PT+ Sbjct: 4588 ------------PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTT 4635 Query: 481 SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVS---------PSIGRMAAT---PGA 528 S S + S G T +++TT T T AT + T S PS+ A T G+ Sbjct: 4636 SGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGS 4695 Query: 529 ATYVKTTSGSI-ITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGK 587 T +T G+ IT V S AT S S + TT+P V+ T Sbjct: 4696 TTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLP------VLTSTATKST 4749 Query: 588 GTTIQGLPGKNVVTT----LLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGS 643 T+ +P + TT T+ T+ T + P T T + T + S Sbjct: 4750 ATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPE-TTHTSTVLTTTATMTRATNS 4808 Query: 644 TVQPAAKIIPTKIV 657 T P++ + T+I+ Sbjct: 4809 TATPSSTLGTTRIL 4822 Score = 83.6 bits (205), Expect = 1e-15 Identities = 116/530 (21%), Positives = 201/530 (37%), Gaps = 68/530 (12%) Query: 108 PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164 P T TVT + A + Q A P + T + V TS+ +TP+S+P + ++ Sbjct: 4456 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPSSSPGTATALP 4511 Query: 165 TVKSPRPASPASNVVVLPSGS-----------TVYVKSVSCSDEDEKPRKRRRTNSSSSS 213 ++S A++ +PS S T ++S + P + +++ Sbjct: 4512 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTAT 4571 Query: 214 PVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS---PVKITFTKPSTQT 270 P S T + P + + S P + PV I+ T T T Sbjct: 4572 ATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTT 4631 Query: 271 TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL 330 T TT+ + ++ P +T +L+ + A + S T+ PP + T + Sbjct: 4632 TPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTA---- 4687 Query: 331 VSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLV 390 + ++ S++ PS P T +T V++ST + +T ++ S+S+ + A+T LP L Sbjct: 4688 -TTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATT-LPV---LT 4742 Query: 391 SAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQI 450 S T+ A S + V QT ++ S + P+ + Sbjct: 4743 STATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETT------------ 4790 Query: 451 KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAI-MTTKLVTTPTGTQAT 509 S +L TAT+ ++NS S+ G + T+L TT T T AT Sbjct: 4791 -------------HTSTVLT--TTATMTRATNSTATPSSTLGTTRILTELTTTATTTAAT 4835 Query: 510 YTRPTVSPSIGRMAATPGAATYVKTTSGSIITV-VPKSLATLGGKIISSNIVSGTTTKIT 568 + T+S +TPG T++ T +I TV VP + + T + Sbjct: 4836 GSTATLS-------STPG-TTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMA 4887 Query: 569 TIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTG 618 T+P T+ + + T G T LP ++ PTG Sbjct: 4888 TMP-TATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTG 4936 Score = 82.4 bits (202), Expect = 3e-15 Identities = 121/533 (22%), Positives = 197/533 (36%), Gaps = 56/533 (10%) Query: 147 TSTTSTPTSTP----------------VPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 TS+T+ P+STP +GS AT S +P V+ P+ + Sbjct: 4237 TSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATS 4296 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 S + S R T + K +V P+ + P+ + + + Sbjct: 4297 SKATSSSS----PRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMS 4352 Query: 251 SLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSST-FVPNILSKSHNYAAVTKLVPT 309 ++ P +P + T T + TT TT + T++PSST IL++ A T Sbjct: 4353 TIHPSSTP-ETTHTS-TVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGP 4410 Query: 310 SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQ 369 + S+T ++T ++ + +S+G S++TPS P T + S+T +V + T + Sbjct: 4411 TATPSSTPGTTWILTELTTTATTTASTG-STATPSSTPGTTWILTEPSTTATVTVPTGST 4469 Query: 370 GVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429 ++S A T P + + PT ++ L + P+ Sbjct: 4470 ATASSTQATAGT--PHVSTTATTPTVTSSKATPSSSPGTATAL----PALRSTATTPTAT 4523 Query: 430 SHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV---TATLPTSSNSPIM 486 S P S + + + + T P + V TAT ++ S Sbjct: 4524 SFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVAT 4583 Query: 487 VVSSNGAIMTTKL-VTTPTGTQATYTRPTVSPSIGR-----MAATPGAATYVKTTSGSII 540 S+ G TTK+ TT TG AT P+ SP ++ T T TTSGS Sbjct: 4584 PSSTPGTAHTTKVPTTTTTGFTAT---PSSSPGTALTPPVWISTTTTPTTTTPTTSGS-- 4638 Query: 541 TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV 600 TV P S+ G ++ +++ TTT + T M + + T GT P Sbjct: 4639 TVTPSSIP---GTTHTARVLTTTTTTVATGSMATPSS-----STQTSGTP----PSLTTT 4686 Query: 601 TTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIP 653 T + A G T + G P T T T K S+ A +P Sbjct: 4687 ATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLP 4739 Score = 78.6 bits (192), Expect = 4e-14 Identities = 144/591 (24%), Positives = 215/591 (36%), Gaps = 81/591 (13%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P P T + +T A S +P+ T TST +TPT+T S Sbjct: 2986 PSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTAT---SSKA 3042 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223 + SPR A+ LP ++ KS + S P ++ + P + Sbjct: 3043 TSSSSPRTAT------TLPVLTSTATKSTATSFT---PIPSFTLGTTGTLP------EQT 3087 Query: 224 VVPVSKTITVPVSGSPKM---SNIMQSIANSLPPHMSPVKITFTKPSTQ-----TTNTTT 275 P++ T+ S +P+ S ++ + A + S + T +T TT TT Sbjct: 3088 TTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3147 Query: 276 QKVIIVTTSPSSTFVPN-ILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334 T +PSST IL++ A VT ++ AS+T+ + S+ + + Sbjct: 3148 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3207 Query: 335 SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP---SPKSLVS 391 SS +TPS P T + ST + +T + +S++ A TRL +P + +S Sbjct: 3208 VI-SSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMS 3266 Query: 392 APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451 T + P+ S + VA PS PG T ++ Sbjct: 3267 TATP--SSTPETVHTSTVLTTTTTTTRATGSVATPSST------------PGTAHTTKVP 3312 Query: 452 QESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQ 507 + T P L PV T T PT+ S + S G T ++TT T T Sbjct: 3313 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTV 3372 Query: 508 ATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTT--- 564 AT G M ATP ++T T S+ T AT G + + GTT Sbjct: 3373 AT----------GSM-ATPSSSTQTSGTPPSLTTTATTITAT--GSTTNPSSTPGTTPIP 3419 Query: 565 TKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT---LLNAGGEKTIQTVPTGAKP 621 +TT T V ++ GTT TT L T++T T A Sbjct: 3420 PVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATS 3479 Query: 622 AILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 IL T +T+P + S PAA T Q T L P P Sbjct: 3480 GILGTTH------ITEPSTVTSHT-PAATTSTT------QHSTPALSSPHP 3517 Score = 76.6 bits (187), Expect = 1e-13 Identities = 148/646 (22%), Positives = 245/646 (37%), Gaps = 86/646 (13%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206 TS+T+TP+STP + I T ++ + A+ +GST ++ S P + Sbjct: 2980 TSSTATPSSTPGTTW-ILTEQTTAATTTAT------TGST----AIPSSTPGTAPPPKVL 3028 Query: 207 TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS-PVKITFTK 265 T+++++ + + P + T T+PV S +S A S P S + T T Sbjct: 3029 TSTATTPTATSSKATSSSSPRTAT-TLPV----LTSTATKSTATSFTPIPSFTLGTTGTL 3083 Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325 P TT T I +++P +T +L+ A T+ + S+T ++T Sbjct: 3084 PEQTTTPMATMSTIHPSSTPETTHTSTVLTTK---ATTTRATSSMSTPSSTPGTTWILTE 3140 Query: 326 SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPS 385 ++ + +++G ++TPS P T + S+T +V + T + ++S A T L Sbjct: 3141 LTTAATTTAATG-PTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGT-LKV 3198 Query: 386 PKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK 445 S + PT I ++ L + P+ S P S + Sbjct: 3199 LTSTATTPTVISSRATPSSSPGTATAL----PALRSTATTPTATSVTAIPSSSLGTAWTR 3254 Query: 446 PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV---SSNGAIMTTKL-VT 501 + + + T P + V T T++ + V S+ G TTK+ T Sbjct: 3255 LSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTT 3314 Query: 502 TPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVS 561 T TG AT P+ SP + T TT GS TV P S+ G ++ +++ Sbjct: 3315 TTTGFTAT---PSSSPGTALTPPVWISTTTTPTTRGS--TVTPSSIP---GTTHTATVLT 3366 Query: 562 GTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKP 621 TTT + T M + + T GT P T + A G T + G P Sbjct: 3367 TTTTTVATGSMATPSS-----STQTSGTP----PSLTTTATTITATGSTTNPSSTPGTTP 3417 Query: 622 ----AILTATRP-ITKMIVTQPKGIGSTVQPA---------AKIIP-----------TKI 656 TAT P T VT +G+T P + +P T Sbjct: 3418 IPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSA 3477 Query: 657 VYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQ---ASRVAEA----GNSSIQEG 709 G G T + +P VT + T Q T L +SR E+ G ++ Sbjct: 3478 TSGILGTTHI-TEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHT 3536 Query: 710 KEEPQNYTDSSSSSTESS---QSSQDSQPVVHVIASRRQD---WSE 749 + + ++ S T +S SS S P+ V+ + + WSE Sbjct: 3537 RGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSE 3582 Score = 72.4 bits (176), Expect = 3e-12 Identities = 258/1279 (20%), Positives = 434/1279 (33%), Gaps = 177/1279 (13%) Query: 108 PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164 P T TVT + A + Q A P + T + V TS+ +TP S+P + ++ Sbjct: 3728 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPFSSPGTATALP 3783 Query: 165 TVKSPRPASPASNVVVLPSGS-----------TVYVKSVSCSDEDEKPRKRRRTNSSSSS 213 ++S A++ +PS S T ++S + P + +++ Sbjct: 3784 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 3843 Query: 214 PVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP---HMSPVKITFTKPSTQT 270 + P S T + P + ++ S P PV I ST T Sbjct: 3844 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWI-----STTT 3898 Query: 271 TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL 330 T TT+ + ++ P +T P +L+ + A + S T+ PP +IT + +++ Sbjct: 3899 TPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTA-TTI 3957 Query: 331 VSNSSSGSSSSTP--SPIPNTVAVTAVV-SSTPSVVMSTVAQGV--------STSAIKMA 379 + S+ + SSTP +PIP + TA ++T S V + A G +T+ Sbjct: 3958 TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGR 4017 Query: 380 STRLPSPKSLVSAPTQILA-QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQ-- 436 S SP ++ +A T + H P T +P P Sbjct: 4018 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSR 4077 Query: 437 --QSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAI 494 +SP PG T + T PSK + + PTS +PI Sbjct: 4078 TTESPPSPG---TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTS--API--------- 4123 Query: 495 MTTKLVTTPTGTQAT------YTRPTVSPSIG------RMAATPGAATYVKTTSGSIITV 542 T +VTT Q Y+ P PS G + A GA + G Sbjct: 4124 --TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAV--CEQPLGLECRA 4179 Query: 543 VPKSLATLG--GKIISSNIVSGTTTK----ITTIPMTSKPNVIVV---------QKTTGK 587 + LG G+++ ++ G + + M + V T Sbjct: 4180 QAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSS 4239 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPT-------GAKPAILTATRPITKMIVTQPKG 640 PG + T L T T T G P T P T T K Sbjct: 4240 TAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKA 4299 Query: 641 IGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQAT--VVSEQTRQLVT--ETLQQAS 696 S+ A +P + T + P P + T + EQT V T+ +S Sbjct: 4300 TSSSSPRTATTLPV-LTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSS 4358 Query: 697 RVAEAGNSSIQEGKEEPQNYTDSSSSS-------------TESSQSSQDSQPVVHVIASR 743 S++ K T S+S+ T ++ ++ + P ++ Sbjct: 4359 TPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 4418 Query: 744 RQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLS 803 W E+ T+ T S+ + S+T +L TT + P T S Sbjct: 4419 GTTWILTELT--TTATTTASTGSTATPSSTPGTTWILTEPSTTATVTV---PTGSTATAS 4473 Query: 804 QMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPS 863 TQ +P + A + V T + GT A P L S + P S Sbjct: 4474 S-------TQATAGTPHVSTTATTPT--VTSSKATPSSSPGTATALPALRSTATTPTATS 4524 Query: 864 ---QPQRTL-LQHVAQSQTATQTSVVVKSIPASSPGAI-THIMQQALSSHTAFTKHSEEL 918 P +L SQT T T+ + + P+S+P + T + A ++ T T Sbjct: 4525 FTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATP 4584 Query: 919 GTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQ 978 + G T P T + T + S+ PP+ + T T Sbjct: 4585 SSTPGTAH--TTKVPTT---TTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGST 4639 Query: 979 TIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQ 1038 H + + T A P Q + P P+L Sbjct: 4640 VTPSSIPGTTHTARVLTTTT-----TTVATGSMATPSSSTQTSGTP--------PSLTT- 4685 Query: 1039 PPQTVVQVLAV-KTTQQLPKLQQAPNQPKIYVQPQTPQSQMS-LPASSEKQTASQVEQPI 1096 T + A TT P P + TP + S +SS +TA+ + P+ Sbjct: 4686 ---TATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTL--PV 4740 Query: 1097 ITQGSSVTKITFEGRQP-PTVTKITGGSSVPKLTSPVTSISPIQAS---EKTAVSDILKM 1152 +T S+ TK T P P+ T T + + T+P++++S I S E T S +L Sbjct: 4741 LT--STATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTT 4798 Query: 1153 SLMEAQIDTNV--------EHMIVDPPKKALATSMLTGEAGSL---PSTHMVVAGMANST 1201 + + + I+ T+ TG +L P T ++ + Sbjct: 4799 TATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIA 4858 Query: 1202 PQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIP 1261 + ++ ST+G++ T + + A T + + +PA ++ ++P Sbjct: 4859 TVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPA-VLPSSLP 4917 Query: 1262 QYAIPCHSSSNV-VVEPSG 1279 +++ SSS + + P+G Sbjct: 4918 TFSVSTVSSSVLTTLRPTG 4936 Score = 70.5 bits (171), Expect = 1e-11 Identities = 107/426 (25%), Positives = 161/426 (37%), Gaps = 62/426 (14%) Query: 260 KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKP 319 K+T T +T++T +T +++P +T+ IL++ A VT VPT A+ + Sbjct: 3698 KLTTTATTTESTGSTATP----SSTPGTTW---ILTEPSTTATVT--VPTGSTATASSTQ 3748 Query: 320 PVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMA 379 T S+ + + SS +TP P T + ST + +T + +S++ Sbjct: 3749 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 3808 Query: 380 STRLP---SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQ 436 TRL +P + +S T + P+ S + VA PS Sbjct: 3809 WTRLSQTTTPTATMSTATP--SSTPETAHTSTVLTTTATTTRATGSVATPSST------- 3859 Query: 437 QSPLPPGIKPTIQIKQESGVKI-ITQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNG 492 PG T ++ + +T P PV T T PT+S S + S G Sbjct: 3860 -----PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 3914 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 T ++TT T T AT G M ATP ++T T S+IT AT G Sbjct: 3915 TTHTPTVLTTTTTTVAT----------GSM-ATPSSSTQTSGTPPSLITTATTITAT--G 3961 Query: 553 KIISSNIVSGTT---TKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT---LLNA 606 + + GTT +TT T V ++ GTT TT L+ Sbjct: 3962 STTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSP 4021 Query: 607 GGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQV 666 T++T T A L T +T+P G++ PAA T Q T Sbjct: 4022 SSPHTVRTAWTSATSGTLGTTH------ITEP-STGTSHTPAATTGTT------QHSTPA 4068 Query: 667 LIKPKP 672 L P P Sbjct: 4069 LSSPHP 4074 Score = 66.2 bits (160), Expect = 2e-10 Identities = 106/465 (22%), Positives = 179/465 (38%), Gaps = 97/465 (20%) Query: 108 PQTAFTVT----ANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P T TVT + A A++ +L V T + V S+ +TP+S+P + ++ Sbjct: 3170 PSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVI----SSRATPSSSPGTATAL 3225 Query: 164 ATVKSPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVP 221 ++S A++V +PS S T + + + P T + SS+P + V Sbjct: 3226 PALRSTATTPTATSVTAIPSSSLGTAWTRL----SQTTTPTATMSTATPSSTP---ETVH 3278 Query: 222 KAVVPVSKTITVPVSGSPKMSNIMQSIANSLP------------PHMSPVKITFTKP--- 266 + V + T T +GS + A++ P SP T P Sbjct: 3279 TSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP-GTALTPPVWI 3337 Query: 267 STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS 326 ST TT TT + ++ P +T +L+ + A + S T+ PP +T + Sbjct: 3338 STTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS-LTTT 3396 Query: 327 QSSLVSNSSSGSSSSTP--SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP 384 +++ + S+ + SSTP +PIP + TA +TP+ STV T + + +T P Sbjct: 3397 ATTITATGSTTNPSSTPGTTPIPPVLTTTA---TTPAATSSTV-----TPSSALGTTHTP 3448 Query: 385 SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGI 444 P +A T H +S LPP Sbjct: 3449 -PVPNTTATT---------HGRS--------------------------------LPPSS 3466 Query: 445 KPTIQI---KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVT 501 T++ SG+ T +PS + AT T+ +S + S + + TT+ Sbjct: 3467 PHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPP 3526 Query: 502 TPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 +P T +TR T + T AT KT + +++ P S Sbjct: 3527 SPGTTTPGHTRGT--------SRTTATATPSKTRTSTLLPSSPTS 3563 Score = 66.2 bits (160), Expect = 2e-10 Identities = 111/498 (22%), Positives = 184/498 (36%), Gaps = 60/498 (12%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPS---GSTVYVKSVSCSDEDEKPRK 203 TS+T+TP+STP + + + + + ++ PS G+T + S + P Sbjct: 3680 TSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 3739 Query: 204 RRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQ-SIANSLPPHMS----P 258 T SS+ + VS T T P S K + A +LP S P Sbjct: 3740 STATASST-------QATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 3792 Query: 259 VKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQK 318 +FT + + TT + + TT+P++T S + A + ++ T+ A+TT+ Sbjct: 3793 TATSFTAIPSSSLGTTWTR-LSQTTTPTATMSTATPSSTPETAHTSTVLTTT--ATTTRA 3849 Query: 319 PPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKM 378 V T S S+ G++ +T P T T SS+P T + + Sbjct: 3850 TGSVATPS-------STPGTAHTTKVPTTTTTGFTVTPSSSPGT--------ARTPPVWI 3894 Query: 379 ASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQS 438 ++T P+ P+ + +P V T VA S + Q S Sbjct: 3895 STTTTPTTSGSTVTPSSVPGT-----THTP-----TVLTTTTTTVATGSMATPSSSTQTS 3944 Query: 439 PLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTK 498 PP + T +G + +P PV T T+ + V+ + A+ TT Sbjct: 3945 GTPPSLITTATTITATGSTTNPSSTPGTTPIP-PVLTTTATTPAATSSTVTPSSALGTTH 4003 Query: 499 LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSN 558 P T T+ R ++SPS T + TSG++ T +T G + Sbjct: 4004 TPPVPNTTATTHGR-SLSPSSPHTVRT----AWTSATSGTLGTTHITEPST--GTSHTPA 4056 Query: 559 IVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTG 618 +GTT T + P+ + GTT PG T+ T P+ Sbjct: 4057 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTT---TPGHTTATS------RTTATATPSK 4107 Query: 619 AKPAILTATRPITKMIVT 636 + + L + P + I T Sbjct: 4108 TRTSTLLPSSPTSAPITT 4125 Score = 63.9 bits (154), Expect = 1e-09 Identities = 109/499 (21%), Positives = 183/499 (36%), Gaps = 62/499 (12%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPS---GSTVYVKSVSCSDEDEKPRK 203 TS+T+ P+STP + + + + + ++ PS G+T + S + P Sbjct: 2423 TSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 2482 Query: 204 RRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITF 263 T SS+ + VS T T P S K + P SP T Sbjct: 2483 STATASST-------QATAGTPHVSTTATTPTVTSSKAT-----------PFSSPGTATA 2524 Query: 264 TKP--STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPV 321 ST TT T T I ++S +T+ + T T A+ + P Sbjct: 2525 LPALRSTATTPTATSFTAIPSSSLGTTWT--------RLSQTTTPTATMSTATPSSTPET 2576 Query: 322 VITASQSSLVSNSSSGSSS-STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTS---AIK 377 V T++ + + ++ + S +TPS P T T V+++T + +T + T+ + Sbjct: 2577 VHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVW 2636 Query: 378 MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQ 437 +++T P+ + P+ I +P V T VA S + Q Sbjct: 2637 ISTTTTPTTRGSTVTPSSIPGT-----THTP-----TVLTTTTTTVATGSMATPSSSTQT 2686 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497 S PP + T +G + +P PV T T+ + V+ + A+ TT Sbjct: 2687 SGTPPSLTTTATTITATGSTTNPSSTPGTTPIP-PVLTTTATTPAATSSTVTPSSALGTT 2745 Query: 498 KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557 P T T+ R ++SPS T + TSG++ T +T G + Sbjct: 2746 HTPPVPNTTATTHGR-SLSPSSPHTVRT----AWTSATSGTLGTTHITEPST--GTSHTP 2798 Query: 558 NIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPT 617 +GTT T + P+ + GTT PG T+ T P+ Sbjct: 2799 AATTGTTQHSTPALSSPHPSSRTTESPPSPGTT---TPGHTRATS------RTTATATPS 2849 Query: 618 GAKPAILTATRPITKMIVT 636 + + L + P + I T Sbjct: 2850 KTRTSTLLPSSPTSAPITT 2868 Score = 63.9 bits (154), Expect = 1e-09 Identities = 100/463 (21%), Positives = 167/463 (36%), Gaps = 94/463 (20%) Query: 108 PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164 P T TVT + A + Q A P + T + V TS+ +TP S+P + ++ Sbjct: 2471 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPFSSPGTATALP 2526 Query: 165 TVKSPRPASPASNVVVLPSGS-----------TVYVKSVSCSDEDEKPR--------KRR 205 ++S A++ +PS S T ++S + P Sbjct: 2527 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTT 2586 Query: 206 RTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265 T + ++ V +K +T +G + A +LP + Sbjct: 2587 ATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWI--------- 2637 Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325 ST TT TT + ++ P +T P +L+ + A + S T+ PP +T Sbjct: 2638 -STTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPP-SLTT 2695 Query: 326 SQSSLVSNSSSGSSSSTP--SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRL 383 + +++ + S+ + SSTP +PIP + TA +TP+ STV T + + +T Sbjct: 2696 TATTITATGSTTNPSSTPGTTPIPPVLTTTA---TTPAATSSTV-----TPSSALGTTHT 2747 Query: 384 PSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPG 443 P P +A T H +S SP P Sbjct: 2748 P-PVPNTTATT---------HGRS-----------------------------LSPSSPH 2768 Query: 444 IKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTP 503 T SG T +PS AT T+ +S + S + + TT+ +P Sbjct: 2769 TVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP 2828 Query: 504 TGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 T +TR T + T AT KT + +++ P S Sbjct: 2829 GTTTPGHTRAT--------SRTTATATPSKTRTSTLLPSSPTS 2863 Score = 63.5 bits (153), Expect = 1e-09 Identities = 116/495 (23%), Positives = 173/495 (34%), Gaps = 89/495 (17%) Query: 147 TSTTSTPTSTP--------VPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDED 198 TS+T+TP+STP + + T + A+P S + P + + + Sbjct: 1894 TSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATT----- 1948 Query: 199 EKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSP 258 P + SSSP +P + T T P + S P S Sbjct: 1949 --PTVTSSKATPSSSPGTATALP----ALRSTATTPTATS------------VTPIPSSS 1990 Query: 259 VKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQK 318 + T+T+ S TT T T T +PSST P + ST Sbjct: 1991 LGTTWTRLSQTTTPTATMS----TATPSST-------------------PETAHTSTVLT 2027 Query: 319 PPVVITASQSSLVSNSSS-GSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIK 377 T + S+ + SS+ G++ +T P T TA SS+P + T + Sbjct: 2028 ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL--------TPPVW 2079 Query: 378 MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQ 437 +++T P+ + P+ I V T VA S + Q Sbjct: 2080 ISTTTTPTTRGSTVTPSSI----------PGTTHTATVLTTTTTTVATGSMATPSSSTQT 2129 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497 S PP + T +G + +P PV T T+ + V+ + A+ TT Sbjct: 2130 SGTPPSLTTTATTITATGSTTNPSSTPGTTPIP-PVLTTTATTPAATSNTVTPSSALGTT 2188 Query: 498 KLVTTPTGTQATYTR--PTVSPSIGRMAATPGAATYVKTTS-GSIITVVPKSLATLGG-- 552 P T+ R P SP R A T + + TT TV +LA G Sbjct: 2189 HTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTT 2248 Query: 553 ----KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLL-NAG 607 +SS S TT+ P T+ P T TT P K +TLL ++ Sbjct: 2249 QHSTPALSSPHPSSRTTESPPSPGTTTPG----HTTATSRTTATATPSKTRTSTLLPSSP 2304 Query: 608 GEKTIQTVPT-GAKP 621 I TV T G +P Sbjct: 2305 TSAPITTVVTMGCEP 2319 Score = 63.2 bits (152), Expect = 2e-09 Identities = 95/391 (24%), Positives = 144/391 (36%), Gaps = 54/391 (13%) Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325 PST T++T +++P +T++ + + A T T T PP V+T Sbjct: 1889 PSTPATSSTATP----SSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 1944 Query: 326 SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP- 384 + ++ + SS +TPS P T + ST + +T + +S++ TRL Sbjct: 1945 TATT----PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQ 2000 Query: 385 --SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 +P + +S T + P+ S VA PS P Sbjct: 2001 TTTPTATMSTATP--SSTPETAHTSTVLTATATTTGATGSVATPSST------------P 2046 Query: 443 GIKPTIQIKQESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTK 498 G T ++ + T P L PV T T PT+ S + S G T Sbjct: 2047 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTAT 2106 Query: 499 LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSN 558 ++TT T T AT G M ATP ++T T S+ T AT G + + Sbjct: 2107 VLTTTTTTVAT----------GSM-ATPSSSTQTSGTPPSLTTTATTITAT--GSTTNPS 2153 Query: 559 IVSGTT---TKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT---LLNAGGEKTI 612 GTT +TT T V ++ GTT + TT L T+ Sbjct: 2154 STPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTV 2213 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGS 643 +T T A IL T +T+P + S Sbjct: 2214 RTAWTSATSGILGTTH------ITEPSTVTS 2238 Score = 62.8 bits (151), Expect = 2e-09 Identities = 94/458 (20%), Positives = 169/458 (36%), Gaps = 83/458 (18%) Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK 167 P T T TA+ + A P + + + TS+ +TP+S+P + ++ ++ Sbjct: 1913 PTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALR 1972 Query: 168 SPRPASPASNVVVLPSGS-----------TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVV 216 S A++V +PS S T ++S + P + +++ Sbjct: 1973 STATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT 2032 Query: 217 LKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS---PVKITFTKPSTQTTNT 273 P S T + P + + S P + PV I ST TT T Sbjct: 2033 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWI-----STTTTPT 2087 Query: 274 TTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSN 333 T + ++ P +T +L+ + A + S T+ PP +T + +++ + Sbjct: 2088 TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPP-SLTTTATTITAT 2146 Query: 334 SSSGSSSSTP--SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVS 391 S+ + SSTP +PIP + TA +TP+ +TV +SA+ T P P ++ + Sbjct: 2147 GSTTNPSSTPGTTPIPPVLTTTA---TTPAATSNTV---TPSSALGTTHTP-PVPNTMAT 2199 Query: 392 APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQ-- 449 H +S LPP T++ Sbjct: 2200 T-----------HGRS--------------------------------LPPSSPHTVRTA 2216 Query: 450 -IKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQA 508 SG+ T +PS + + AT T+ +S + S + + TT+ +P T Sbjct: 2217 WTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP 2276 Query: 509 TYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 +T T + T AT KT + +++ P S Sbjct: 2277 GHTTAT--------SRTTATATPSKTRTSTLLPSSPTS 2306 Score = 62.4 bits (150), Expect = 3e-09 Identities = 104/416 (25%), Positives = 148/416 (35%), Gaps = 55/416 (13%) Query: 270 TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 TT TTT+ T S+ IL++ A VT VPT A+ + T S+ Sbjct: 2444 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVT--VPTGSTATASSTQATAGTPHVST 2501 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP---SP 386 + + SS +TP P T + ST + +T + +S++ TRL +P Sbjct: 2502 TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 2561 Query: 387 KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKP 446 + +S T + P+ S VA PS PG Sbjct: 2562 TATMSTATP--SSTPETVHTSTVLTTTATTTGATGSVATPSST------------PGTAH 2607 Query: 447 TIQIKQESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTKLVTT 502 T ++ + T P PV T T PT+ S + S G T ++TT Sbjct: 2608 TTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTT 2667 Query: 503 PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562 T T AT G M ATP ++T T S+ T AT G + + G Sbjct: 2668 TTTTVAT----------GSM-ATPSSSTQTSGTPPSLTTTATTITAT--GSTTNPSSTPG 2714 Query: 563 TT---TKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT---LLNAGGEKTIQTVP 616 TT +TT T V ++ GTT TT L+ T++T Sbjct: 2715 TTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAW 2774 Query: 617 TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A L T +T+P G++ PAA T Q T L P P Sbjct: 2775 TSATSGTLGTTH------ITEP-STGTSHTPAATTGTT------QHSTPALSSPHP 2817 Score = 60.5 bits (145), Expect = 1e-08 Identities = 94/451 (20%), Positives = 153/451 (33%), Gaps = 75/451 (16%) Query: 322 VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381 V+ S ++ + SS++TPS P T + ++T + ST + TS ++ A Sbjct: 1879 VLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTA-- 1936 Query: 382 RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLP 441 P PK L + T P+ S + P S Sbjct: 1937 --PPPKVLTTTAT------------------------------TPTVTSSKATPSSS--- 1961 Query: 442 PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVT 501 PG + + + V P T T + + +P +S+ T + Sbjct: 1962 PGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAH 2021 Query: 502 TPTGTQATYTRPTVSPSIGRMAATPGAA--TYVKTTSGSIITVVPKS------------- 546 T T AT T + S+ ++TPG A T V TT+ + T P S Sbjct: 2022 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS 2081 Query: 547 ---LATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT-T 602 T G ++ + + GTT T + T+ T T G P T T Sbjct: 2082 TTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTAT 2141 Query: 603 LLNAGGEKTIQTVPTGAKP----AILTATRP-ITKMIVTQPKGIGSTVQPAA-------- 649 + A G T + G P TAT P T VT +G+T P Sbjct: 2142 TITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTH 2201 Query: 650 -----KIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNS 704 P + T ++ +T +TV S T T T Q ++ + + Sbjct: 2202 GRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS-HTLAATTGTTQHSTPALSSPHP 2260 Query: 705 SIQEGKEEPQNYTDSSSSSTESSQSSQDSQP 735 S + + P T + +T +S+++ + P Sbjct: 2261 SSRTTESPPSPGTTTPGHTTATSRTTATATP 2291 Score = 59.3 bits (142), Expect = 2e-08 Identities = 82/359 (22%), Positives = 134/359 (37%), Gaps = 33/359 (9%) Query: 297 SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356 ++ + T ++ + S+T ++T ++ + S+GS++ TPS P T + Sbjct: 2413 NYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTA-TPSSTPGTTWILTEP 2471 Query: 357 SSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQ 416 S+T +V + T + ++S A T P + + PT ++ L Sbjct: 2472 STTATVTVPTGSTATASSTQATAGT--PHVSTTATTPTVTSSKATPFSSPGTATAL---- 2525 Query: 417 QQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV--- 473 + P+ S P S + + + + T P + V Sbjct: 2526 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT 2585 Query: 474 TATLPTSSNSPIMVVSSNGAIMTTK-LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYV 532 TAT ++ S S+ G TTK L TT TG AT P+ SP R + T Sbjct: 2586 TATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTAT---PSSSPGTARTLPVWISTTTT 2642 Query: 533 KTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQ 592 TT GS TV P S+ G + +++ TTT + T M + + T GT Sbjct: 2643 PTTRGS--TVTPSSIP---GTTHTPTVLTTTTTTVATGSMATPSS-----STQTSGTP-- 2690 Query: 593 GLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651 P T + A G T + G P P+ T P STV P++ + Sbjct: 2691 --PSLTTTATTITATGSTTNPSSTPGTTP-----IPPVLTTTATTPAATSSTVTPSSAL 2742 Score = 58.5 bits (140), Expect = 4e-08 Identities = 85/358 (23%), Positives = 129/358 (36%), Gaps = 33/358 (9%) Query: 299 NYAAVTKLVPTSVIASTTQKPPVV-ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS 357 NY TS A+ + P I ++ + + S S++TPS P T + S Sbjct: 3670 NYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPS 3729 Query: 358 STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQ 417 +T +V + T + ++S A T P + + PT ++ L Sbjct: 3730 TTATVTVPTGSTATASSTQATAGT--PHVSTTATTPTVTSSKATPFSSPGTATAL----P 3783 Query: 418 QTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV---T 474 + P+ S P S + + + + T P V T Sbjct: 3784 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 3843 Query: 475 ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534 AT ++ S S+ G TTK+ TT T T T T P+ SP R + T T Sbjct: 3844 ATTTRATGSVATPSSTPGTAHTTKVPTTTT-TGFTVT-PSSSPGTARTPPVWISTTTTPT 3901 Query: 535 TSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGL 594 TSGS TV P S+ G + +++ TTT + T M T T G Sbjct: 3902 TSGS--TVTPSSVP---GTTHTPTVLTTTTTTVATGSMA----------TPSSSTQTSGT 3946 Query: 595 PGKNVVT-TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651 P + T T + A G T + G P P+ T P STV P++ + Sbjct: 3947 PPSLITTATTITATGSTTNPSSTPGTTP-----IPPVLTTTATTPAATSSTVTPSSAL 3999 Score = 56.2 bits (134), Expect = 2e-07 Identities = 97/439 (22%), Positives = 158/439 (35%), Gaps = 38/439 (8%) Query: 298 HNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPS-----PIPNTVAV 352 +++ T ++ S+T ++T ++ + +S+GS+++ S P P + Sbjct: 1885 YSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 1944 Query: 353 TAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQI-LAQFPKQHQQSPKQQ 411 TA +TP+V S S +T LP+ +S + PT + P + + Sbjct: 1945 TA---TTPTVTSSKATPSSSPGT----ATALPALRSTATTPTATSVTPIPSSSLGTTWTR 1997 Query: 412 LYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPK 471 L QT A S + P+ + + T +G PS Sbjct: 1998 L----SQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATG-----SVATPSSTPGT 2048 Query: 472 PVTATLPTSSNSPIMVV-SSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAAT 530 T +PT++ + SS+ T V T T T TV+PS + T AT Sbjct: 2049 AHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPS--SIPGTTHTAT 2106 Query: 531 YVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590 + TT+ TV S+AT SS SGT +TT T + TT +T Sbjct: 2107 VLTTTT---TTVATGSMATPS----SSTQTSGTPPSLTTTATT----ITATGSTTNPSST 2155 Query: 591 IQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK 650 P V+TT + P+ A T P T M T + + + + Sbjct: 2156 PGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNT-MATTHGRSLPPSSPHTVR 2214 Query: 651 IIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGK 710 T G G T + +P VT + T Q T L + S G Sbjct: 2215 TAWTSATSGILGTTHI-TEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGT 2273 Query: 711 EEPQNYTDSSSSSTESSQS 729 P + T +S ++ ++ S Sbjct: 2274 TTPGHTTATSRTTATATPS 2292 Score = 53.5 bits (127), Expect = 1e-06 Identities = 95/441 (21%), Positives = 157/441 (35%), Gaps = 82/441 (18%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTP------ 157 P P+T T T S+ P+ T T+TT+ T+TP Sbjct: 4555 PSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGT 4614 Query: 158 --VPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTN------S 209 P I+T +P +P + SGSTV S+ + + T + Sbjct: 4615 ALTPPVWISTTTTPTTTTPTT------SGSTVTPSSIPGTTHTARVLTTTTTTVATGSMA 4668 Query: 210 SSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQ 269 + SS P ++ + TIT S + S P +P+ T ST Sbjct: 4669 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSST----------PGTTPITPVLT--STA 4716 Query: 270 TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKL--VPTSVIASTTQKPPVVIT-AS 326 TT T ++SP + +L+ + + T +P+S + +T P T S Sbjct: 4717 TTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMS 4776 Query: 327 QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS--TPSVVMST--VAQGVSTSAIKMASTR 382 S + SS+ ++ T + + T +T +S TPS + T + ++T+A A+T Sbjct: 4777 TMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATG 4836 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S T IL +PS ++ P S Sbjct: 4837 STATLSSTPGTTWIL--------------------------TEPSTIATVMVPTGS---- 4866 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS-----NSPIMVVSSNGAIMTT 497 T G + V +P +T+P+SS +P ++ SS + T Sbjct: 4867 ----TATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSS----LPT 4918 Query: 498 KLVTTPTGTQATYTRPTVSPS 518 V+T + + T RPT PS Sbjct: 4919 FSVSTVSSSVLTTLRPTGFPS 4939 Score = 50.8 bits (120), Expect = 8e-06 Identities = 70/319 (21%), Positives = 122/319 (38%), Gaps = 41/319 (12%) Query: 105 RLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTP--VPSGS 162 R++ T TV ++A + S P+ T + + + T +T+ P+STP P Sbjct: 4653 RVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTI--TATGSTTNPSSTPGTTPITP 4710 Query: 163 IATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPK 222 + T + PA+ +S S T V S ++ S+ +P Sbjct: 4711 VLTSTATTPAATSSKATSSSSPRTATTLPVLTS------------TATKSTATSFTPIPS 4758 Query: 223 AVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVT 282 + + T TVP + MS M +I S P + T +T T T + T Sbjct: 4759 STLWT--TWTVPAQTTTPMST-MSTIHTSSTPETTHTSTVLTTTATMTRATNS------T 4809 Query: 283 TSPSSTF-VPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSS 341 +PSST IL++ A T ++ S+T ++T + +GS+++ Sbjct: 4810 ATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTAT 4869 Query: 342 TPSPI--PNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQ 399 S + +T V +++ P+ STV S+S + T P SL + ++ Sbjct: 4870 ASSTLGTAHTPKVVTTMATMPTATASTVP---SSSTVGTTRTPAVLPSSLPTFSVSTVSS 4926 Query: 400 ----------FPKQHQQSP 408 FP H +P Sbjct: 4927 SVLTTLRPTGFPSSHFSTP 4945 Score = 50.1 bits (118), Expect = 1e-05 Identities = 172/904 (19%), Positives = 287/904 (31%), Gaps = 178/904 (19%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P P+TA T T S+ P+ T T+TT+ T+T PS S Sbjct: 2013 PSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT--PSSSP 2070 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTN------SSSSSPVVL 217 T +P P ++ GSTV S+ + T ++ SS Sbjct: 2071 GTALTP-PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQT 2129 Query: 218 KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQK 277 P ++ + TIT S + S P +P+ P TT TT Sbjct: 2130 SGTPPSLTTTATTITATGSTTNPSST----------PGTTPI------PPVLTTTATTPA 2173 Query: 278 VIIVTTSPSSTF-------VPNIL----------SKSHNYAAVTKLVPTSVIASTTQKPP 320 T +PSS VPN + S H + ++ +T P Sbjct: 2174 ATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 2233 Query: 321 VVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAS 380 +T+ + + ++ S+ + SP P++ + S + T A +T+ + Sbjct: 2234 STVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK 2293 Query: 381 TRLPS--PKSLVSAPTQILAQFPKQHQQSPKQQL-----------------YQVQQQTQQ 421 TR + P S SAP + + Q + + L ++ Sbjct: 2294 TRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGA 2353 Query: 422 QVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKI---LPKPVTATLP 478 QP + + Q Q + ++ + G+ + + Q K + Sbjct: 2354 VCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGL-VCRNREQVGKFKMCFNYEIRVFCC 2412 Query: 479 TSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTV--SPSIGRMAATPGAATYVKTTS 536 + P +S+ A+ ++ TT T+ T T T + S ++TPG + S Sbjct: 2413 NYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPS 2472 Query: 537 GSIITVVP--------KSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVV-----QK 583 + VP + AT G +S+ + T T P +S + Sbjct: 2473 TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTA 2532 Query: 584 TTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGS 643 TT T+ +P ++ TT + T P M P Sbjct: 2533 TTPTATSFTAIPSSSLGTTWTR-----------------LSQTTTPTATMSTATPSSTPE 2575 Query: 644 TVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGN 703 TV + + T G G T +T + T +++T T Sbjct: 2576 TVHTSTVLTTTATTTGATGSV--------ATPSSTPGTAHTTKVLTTT------------ 2615 Query: 704 SSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQ 763 T +++ SS + + PV W I+ T+PT Sbjct: 2616 -------------TTGFTATPSSSPGTARTLPV----------W----ISTTTTPTTRGS 2648 Query: 764 DVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPS 823 V+ S T+ +L TTV MA P TQ S PS Sbjct: 2649 TVTPSSIPGTTHTPTVLTTTTTTVA-------------TGSMATPSSSTQT---SGTPPS 2692 Query: 824 IAVVESELVAEYITTE-RTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQT 882 + + + A TT + GT P+L + + P A S T T + Sbjct: 2693 LTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTP-------------AATSSTVTPS 2739 Query: 883 SVV--VKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYR 940 S + + P + A TH ++LS + T + G + +P TG + Sbjct: 2740 SALGTTHTPPVPNTTATTH--GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHT 2797 Query: 941 SALT 944 A T Sbjct: 2798 PAAT 2801 Score = 50.1 bits (118), Expect = 1e-05 Identities = 100/466 (21%), Positives = 158/466 (33%), Gaps = 79/466 (16%) Query: 319 PPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSST------PSVVMSTVAQGVS 372 P TA+ SS + + +T + T TA+ SST P V+ ST + Sbjct: 2978 PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTA 3037 Query: 373 TSAIKMASTRLPSPKS------LVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQP 426 TS+ +T SP++ L S T+ A + +QT +A Sbjct: 3038 TSS---KATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094 Query: 427 SPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSK------ILPKPVTATLPTS 480 S + P+ + T+ + + + + PS IL + TA T+ Sbjct: 3095 STIHPSSTPETTH-----TSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTA 3149 Query: 481 SNSPIMVVSSNGAI-------MTTKLVTTPTGTQA-----------------TYTRPTVS 516 + P SS TT VT PTG+ A T T PTV Sbjct: 3150 ATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVI 3209 Query: 517 PSIGRMAATPGAATYV-------KTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITT 569 S +++PG AT + T + + +T +P S +LG + + T ++T Sbjct: 3210 SSRATPSSSPGTATALPALRSTATTPTATSVTAIPSS--SLGTAWTRLSQTTTPTATMST 3267 Query: 570 IPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRP 629 +S P + TT G V T + G VPT Sbjct: 3268 ATPSSTPETVHTSTVLTTTTTTTRATGS--VATPSSTPGTAHTTKVPTTTTTGFTATPSS 3325 Query: 630 ITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT 689 +T P I +T P + G T T ATV++ T + T Sbjct: 3326 SPGTALTPPVWISTTTTPTTR-----------GSTVTPSSIPGTTHTATVLTTTTTTVAT 3374 Query: 690 ETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQP 735 ++ S SS Q P T +++ + S ++ S P Sbjct: 3375 GSMATPS-------SSTQTSGTPPSLTTTATTITATGSTTNPSSTP 3413 Score = 47.8 bits (112), Expect = 7e-05 Identities = 94/394 (23%), Positives = 142/394 (36%), Gaps = 95/394 (24%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P P+T T T S+ P+ T T+TT+ T+T PS S Sbjct: 2570 PSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTAT--PSSSP 2627 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223 T ++ P ++ GSTV S+ ++ +P VL Sbjct: 2628 GTART-LPVWISTTTTPTTRGSTVTPSSIP---------------GTTHTPTVL------ 2665 Query: 224 VVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTT 283 + T T +GS M + ++S +P +T +T TT T T TT Sbjct: 2666 ----TTTTTTVATGS------MATPSSSTQTSGTPPSLT----TTATTITATGS----TT 2707 Query: 284 SPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVIT-----ASQSSLVSNSSSGS 338 +PSST TT PPV+ T A+ SS V+ SS+ Sbjct: 2708 NPSST------------------------PGTTPIPPVLTTTATTPAATSSTVTPSSALG 2743 Query: 339 SSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILA 398 ++ TP P+PNT A T S +PS + S ++ + +T + P + S Sbjct: 2744 TTHTP-PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS------- 2795 Query: 399 QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKI 458 +P Q T ++ P P S + +SP PG + S Sbjct: 2796 -------HTPAATTGTTQHST-PALSSPHPSS---RTTESPPSPGTTTPGHTRATSRT-- 2842 Query: 459 ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 T PSK + + PTS +PI V + G Sbjct: 2843 -TATATPSKTRTSTLLPSSPTS--APITTVVTMG 2873 Score = 46.6 bits (109), Expect = 2e-04 Identities = 127/564 (22%), Positives = 189/564 (33%), Gaps = 94/564 (16%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206 T+TT STP P+ S ++P PAS + V L G T PR Sbjct: 1624 TTTTQALFSTPQPTSSPGLTRAP-PASTTA-VPTLSEGLT-------------SPRYTST 1668 Query: 207 TNSSSS-SPVVLKEVPKAVVPVSKTITVPV-SGSPKMSNIMQSIANSLPPHMSPVKITFT 264 ++++ P + VP T T+P S P + + + S PP ++P + + Sbjct: 1669 LGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATS 1728 Query: 265 KPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVIT 324 + T +T K + T + P + S+ A T T TT P T Sbjct: 1729 RARPTGTASTASKEPLTT-----SLAPTLTSELSTSQAETSTPRT----ETTMSPLTNTT 1779 Query: 325 ASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP 384 SQ + + P + + + ++ A G A K R Sbjct: 1780 TSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENI---RAAGGKMCWAPKSIECRAE 1836 Query: 385 S-PKSLVSAPTQIL------AQFPKQHQQSPKQQL---YQVQQ---QTQQQVAQPSPVSH 431 + P+ + Q+L K Q+ + + Y V+ S Sbjct: 1837 NYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSS 1896 Query: 432 QQQPQQSPLPPGI--KPTIQIKQESGVKIITQQVQPSKILPKP----VTATLPTSSNSPI 485 P +P I KPT + + P P TAT PT ++S Sbjct: 1897 TATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKA 1956 Query: 486 MVVSSNGAIMT----TKLVTTPTGTQAT----------------YTRPTVSPSIGRMAAT 525 SS G TTPT T T T PT + S ++T Sbjct: 1957 TPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSST 2016 Query: 526 PGAA------TYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTS----- 574 P A T TT+G+ +V S + G ++ + + TTT T P +S Sbjct: 2017 PETAHTSTVLTATATTTGATGSVATPS--STPGTAHTTKVPTTTTTGFTATPSSSPGTAL 2074 Query: 575 KPNVIVVQKTT----GKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTG--AKPAILT--- 625 P V + TT G T +PG T+L T TV TG A P+ T Sbjct: 2075 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT----TTTTVATGSMATPSSSTQTS 2130 Query: 626 ATRPITKMIVTQPKGIGSTVQPAA 649 T P T GST P++ Sbjct: 2131 GTPPSLTTTATTITATGSTTNPSS 2154 Score = 43.5 bits (101), Expect = 0.001 Identities = 56/221 (25%), Positives = 89/221 (40%), Gaps = 25/221 (11%) Query: 104 PRLVPQTAFTVTANAVA--NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSG 161 P ++ T TV ++A +++ Q + + P T + S T+ +STP +TP+P Sbjct: 3919 PTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIP-- 3976 Query: 162 SIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVP 221 + T + PA+ +S V + T + V P T+ S SP V Sbjct: 3977 PVLTTTATTPAATSSTVTPSSALGTTHTPPV--------PNTTATTHGRSLSPSSPHTVR 4028 Query: 222 KAVVPVSK------TITVPVSG-SPKMSNIMQSIANSLPPHMSP---VKITFTKPSTQTT 271 A + IT P +G S + + +S P SP + T + PS TT Sbjct: 4029 TAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT 4088 Query: 272 ---NTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPT 309 +TT T +PS T +L S A +T +V T Sbjct: 4089 TPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 4129 >gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] Length = 1542 Score = 86.7 bits (213), Expect = 1e-16 Identities = 224/1145 (19%), Positives = 402/1145 (35%), Gaps = 88/1145 (7%) Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGS---TVYVKSVSCSDEDEKP 201 S +TTST S + + S+++ + PA+ ++ +GS T+ +K+ + Sbjct: 4 SEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG 63 Query: 202 RKRRRTNSSSSSPVVLK----EVPKAVVPVSKTITVPVSGSPKMSNIM---QSIANSLPP 254 + + + S ++ E+ S+ TV +GS + M +S ++ Sbjct: 64 SETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGS 123 Query: 255 HMSPVKITFTKP-------STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + V IT T+ S TTN+TT VT++ S S A T Sbjct: 124 ETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADS 183 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVM 364 T+ ++T + V TA S ++ S++GS ++T S TV+ T ++T S Sbjct: 184 ETTAASTTGSEMTTVFTAG-SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 242 Query: 365 S--TVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQ 422 S T A + + K+++ + S + T + + + + T Sbjct: 243 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 302 Query: 423 VAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSN 482 + + + S + I E+ K+ T + + + ++ Sbjct: 303 ETTAASTTGSEPTMASTMGSETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVG 361 Query: 483 SPIMVVSSNGAIMTTKLV-----TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTS 536 S VS+ G+ TT + +T + T + T + S A+T G+ AT V TT Sbjct: 362 SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG 421 Query: 537 GSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPG 596 TV T S + + +TT T +++ + I + T+ TT G Sbjct: 422 SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEG 481 Query: 597 KNVVTTLLNAGGE-KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGST-------VQPA 648 TT+ AG E KT T + A T T + ST V Sbjct: 482 SE-TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 540 Query: 649 AKIIPTKIVYGQQGKTQVLIKPKPVTF---------------QATVVSEQTRQLVTETLQ 693 + T G + T + T + T VS + T++ + Sbjct: 541 GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 600 Query: 694 QASRVA--EAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHE 751 + A AG+ + + +N T S++ S +S S+ S+ S + E Sbjct: 601 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 660 Query: 752 IAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI-- 809 + T+ + + + S + + E +TT S+ T V I Sbjct: 661 GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITG 720 Query: 810 -QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQR 867 + T+ E+ + + SE+ IT +E T TE + S ++ + + Sbjct: 721 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS--TEGSETTSAST 778 Query: 868 TLLQHVAQSQTATQTSVV----VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGT 920 T + S T+++T++ ++ AS+ G+ T + A S T FT++SE T Sbjct: 779 TGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 838 Query: 921 EEGEVEEMDTLDPQT--GLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQ 978 E + T +T S T + S + + + E ++ + + +T Sbjct: 839 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 898 Query: 979 TIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQ 1038 TI + + + S + T E ++ A T A Sbjct: 899 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 958 Query: 1039 PPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIIT 1098 + ++ V TT A V ++ + A SE T S T Sbjct: 959 TEGS--ELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS-------T 1009 Query: 1099 QGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQ 1158 GS T + EG + TV+ ++ T T+I+ + SE T V+ S A Sbjct: 1010 AGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAV 1067 Query: 1159 IDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVG 1218 T E T TG + ST A + +T ++ ST G Sbjct: 1068 YTTGSETTTTSTEGSETTTVSTTGSETTTAST----ADLETTTVSTS--GSGTTTASTAG 1121 Query: 1219 SSLTT 1223 S TT Sbjct: 1122 SETTT 1126 Score = 79.3 bits (194), Expect = 2e-14 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 234 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 293 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 294 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 353 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 354 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 413 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 414 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 473 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 474 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 533 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 534 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 593 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 594 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 653 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 654 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 713 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 714 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 771 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 772 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 827 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 828 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 887 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 888 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 924 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 925 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 982 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 983 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1031 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1032 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1091 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1092 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1148 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1149 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1204 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136 + A SE TAS T GS T + G + T +S P T+ + Sbjct: 1205 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1257 Query: 1137 PIQASEKTAVS 1147 I SE T S Sbjct: 1258 FIIGSETTIAS 1268 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 164 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 223 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 224 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 282 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 283 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 342 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 343 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 400 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 401 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 460 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 461 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 510 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 511 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 564 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 565 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 624 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 625 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 682 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 683 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 738 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 739 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 797 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 798 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 852 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 853 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 912 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 913 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 972 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 973 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1032 Query: 927 EMDTL 931 E T+ Sbjct: 1033 ETTTV 1037 Score = 50.4 bits (119), Expect = 1e-05 Identities = 111/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 823 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 880 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 881 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 937 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 938 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 996 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 997 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1056 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1057 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1113 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437 + + S T + K S + T + S + + Sbjct: 1114 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1173 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497 + I +G + T + S+ T T T+ + ++ T Sbjct: 1174 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1227 Query: 498 KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557 + T T T T +PS +TT S ++ P + + G + + Sbjct: 1228 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1287 Query: 558 NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616 +I SG T TT+ T+ ++ + T I P TT ++ P Sbjct: 1288 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1344 Query: 617 TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676 +A IV G+G++ A+ T +G + T +P TFQ Sbjct: 1345 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1399 Query: 677 AT 678 T Sbjct: 1400 ET 1401 >gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sapiens] Length = 1064 Score = 84.3 bits (207), Expect = 7e-16 Identities = 175/811 (21%), Positives = 284/811 (35%), Gaps = 96/811 (11%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVL---PSGSTVYVKSVSCSDEDEKPRK 203 +STT T TP+P+GSI T SP P V P ST+ + S R Sbjct: 217 SSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRP 276 Query: 204 RRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITF 263 SS +L P VP ++ T + + +S ++ ++ P IT Sbjct: 277 TATNTLSSLMSNILSSTP---VPSTEMTTSHTTDTNPLSTLVTTL---------PTTITR 324 Query: 264 TKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVI 323 + P+++TT + T + S+T + + + T L PTS TT+ P Sbjct: 325 STPTSETTYPASPTS---TVTDSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPT 381 Query: 324 TASQSSLVSNSSSGSSSSTPSPIPNTVAV-TAVVSSTP--SVVMSTVAQGVSTSAIKMAS 380 T ++ +S S + + S I +TV+ T +SS P S M T V T+ +K Sbjct: 382 TKLVTTTTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPEL 441 Query: 381 TRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPL 440 L + A +Q P + + + + P S + Sbjct: 442 ILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVISAI 501 Query: 441 PPGIKPTIQIKQESG------VKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAI 494 P T SG + +T + S P T T++ +P + Sbjct: 502 TPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTPAPNTEVITSHTTTTTP------PSTL 555 Query: 495 MTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG--SIITVVPK---SLAT 549 +TT T + T +SP+ G + + TY + +G S T +P SL T Sbjct: 556 VTTLPTAIARSTPTSETTYPISPT-GTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPT 614 Query: 550 LGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLP---GKNVVTTLLNA 606 + + + TTT+ T+ S + + TTI P G V T +N Sbjct: 615 IETATTPTTNLGNTTTETTSHSTPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNP 674 Query: 607 GGEKT-IQTV-------PTGAKPAILTATRPITK-MIVTQPKGIGSTVQPAAKIIPTK-- 655 T I T P+ LTA +T V+ + ++V P+A I K Sbjct: 675 SSLSTDISTTTLKNITQPSVGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKEI 734 Query: 656 -----------------IVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRV 698 + + T ++ PVT+ + + T+T +S Sbjct: 735 STLVSTTTTTSPTERMTLTSTENTPTSYILTTSPVTYSFSPSMSASSDWTTDTESISS-- 792 Query: 699 AEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSP 758 A A S++ E T +++S T S+ S V + S +ET+ Sbjct: 793 APAITSTLHTTAESTLAPT-TTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTT 851 Query: 759 TIIYQDVSSES----QSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQE 814 D+S+ES +T+ I + + L+ T + T LS +T Sbjct: 852 LTPTTDISTESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLS------SLTSS 905 Query: 815 KRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVA 874 S PS V+ S+ TT T T V S P + + V Sbjct: 906 ILSSTPVPSTEVITSQ------TTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVT 959 Query: 875 QSQTATQTSVVVK-------SIPASSPGAIT 898 S T T S + S+PA++ IT Sbjct: 960 DSTTETTYSTSITGTLSTEISLPATTSSLIT 990 Score = 83.2 bits (204), Expect = 2e-15 Identities = 167/797 (20%), Positives = 280/797 (35%), Gaps = 125/797 (15%) Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPT------------- 154 P FT AV + + P+ + S V S T+TTS PT Sbjct: 239 PTPVFTTLKTAVTSTS-------PITSTITSTNTVT-SMTTTTSRPTATNTLSSLMSNIL 290 Query: 155 -STPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSS 213 STPVPS + T + ++ V LP T +S S E P T + S++ Sbjct: 291 SSTPVPSTEMTTSHTTDTNPLSTLVTTLP---TTITRSTPTS-ETTYPASPTSTVTDSTT 346 Query: 214 PVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNT 273 + V ++ T++ P + P S+ Q+ + P V T T+ ++Q++ Sbjct: 347 EITYSTV------LTGTLS-PTTTLPPTSSSQQTTETPMTPTTKLVTTT-TETTSQSSLN 398 Query: 274 TTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVI--------------------- 312 + I T S S+T + ++ S T +VPT+ + Sbjct: 399 FSSSAIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPELILLEVHDQRIQAKNPRY 458 Query: 313 -----ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS--------- 358 S+T P T + ++ +S S ++ ++ +P+ + + V+S Sbjct: 459 SQTPFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVISAITPKTTVTSMTTTASGPT 518 Query: 359 --------TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSA-PTQILAQFPKQHQQSPK 409 T S++ ST A +T I +T P +LV+ PT I P P Sbjct: 519 TTNTLSSLTSSILSSTPAP--NTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTYPI 576 Query: 410 QQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTI---------------QIKQES 454 V + S PL PTI + S Sbjct: 577 SPTGTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNLGNTTTETTSHS 636 Query: 455 GVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPT 514 + + + + ++ P SS + + + N + ++T + TT T T+P+ Sbjct: 637 TPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTT---TLKNITQPS 693 Query: 515 VSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKIT-TIPMT 573 V + AAT +T+ ++S ++ T V S ++ K IS+ + + TTT T + +T Sbjct: 694 VGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTSPTERMTLT 753 Query: 574 SKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKM 633 S N T T P ++A + T T + PAI T+T T Sbjct: 754 STENTPTSYILTTSPVTYSFSPS-------MSASSDWTTDTESISSAPAI-TSTLHTTAE 805 Query: 634 IVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQ 693 P S +A + P G Q TF T T + TE+ Sbjct: 806 STLAPTTTNS-FTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFM 864 Query: 694 ---------QASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRR 744 +S +S+ P T ++ SS SS S P VI S+ Sbjct: 865 TPMISTTPITSSMTLRNTMTSMTTAASRPT--TTNTLSSLTSSILSSTPVPSTEVITSQT 922 Query: 745 QDWSEHEIAMETSPTII------YQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQP 798 + + + T PT I + S S ++T T T++ L ++ P Sbjct: 923 TNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTDSTTETTYSTSITGTLSTEISLP 982 Query: 799 TIDLSQMAVPIQMTQEK 815 S + I MT + Sbjct: 983 ATTSSLITKGISMTSTR 999 Score = 78.2 bits (191), Expect = 5e-14 Identities = 190/902 (21%), Positives = 331/902 (36%), Gaps = 143/902 (15%) Query: 119 VANAAIQHNASLPV-----PAETGSKEVVCYSYTS--TTSTPTST------PVPSGSIAT 165 +A+ A H + P+ P +T E + S S T++TPTS P + Sbjct: 59 LASPAPGHRENAPMTLTTSPHDTLISETLLSSLVSSNTSTTPTSKFAFKVETTPPTVLVY 118 Query: 166 VKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV 225 + + P S ++ + +++ V + T +SS +P + + P V Sbjct: 119 LATTECVYPTSFIITISHPTSICVTTTQV------------TFTSSYTPTPVTQKPVTTV 166 Query: 226 PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNT-----------T 274 T T P++ + K ++ M S ++ +P+ S T+T T Sbjct: 167 ----TRTYPMTTTEKGTSAMISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRT 222 Query: 275 TQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334 T++ + T S +T P + + A + TS I ST + T S+ + + Sbjct: 223 TERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTL 282 Query: 335 SSGSSSSTPS-PIPNTVAVTAVVSSTP--SVVMSTVAQGVSTSAIKMASTRLPSPKSLVS 391 SS S+ S P+P+T T+ + T S +++T+ ++ S +T SP S V+ Sbjct: 283 SSLMSNILSSTPVPSTEMTTSHTTDTNPLSTLVTTLPTTITRSTPTSETTYPASPTSTVT 342 Query: 392 ----------------APTQIL--AQFPKQHQQSPKQQLYQVQQQTQQQVAQPS------ 427 +PT L +Q ++P ++ T + +Q S Sbjct: 343 DSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKLVTTTTETTSQSSLNFSSS 402 Query: 428 ---PVSHQQQPQQSPLPP---------GIKPTIQIKQESGVKIITQQVQPSKILPK---- 471 S LPP I PT +K E +I +V +I K Sbjct: 403 AIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPE----LILLEVHDQRIQAKNPRY 458 Query: 472 ---PVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGA 528 P T++ TS + + +++ I T L T T T + T ++ M T Sbjct: 459 SQTPFTSSTATSPETTTLTCTND--ISTESLTTAMTSTTPVISAITPKTTVTSMTTTASG 516 Query: 529 ATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGT--TTKITTIPMT---SKPNVIVVQK 583 T T S S+ + + S ++I+S+ + T +T +TT+P S P Sbjct: 517 PTTTNTLS-SLTSSILSSTPAPNTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTYP 575 Query: 584 TTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGS 643 + GT + T++ T + + + P I TAT P T + T + Sbjct: 576 ISPTGTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNLGNTTTE---- 631 Query: 644 TVQPAAKIIPTKIVYGQQGKTQVLIKPKP------VTFQATVVSEQTRQLVTETLQQASR 697 T + + +Y + I P VTF S + + T TL+ ++ Sbjct: 632 TTSHSTPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTTTLKNITQ 691 Query: 698 VAEAGNSSIQEGKEEPQNYTDSSSSS-----TESSQSSQDSQPVVHVIASRRQDWSEHE- 751 + + + +T SSSS+ T S+ S Q+ + + + S S E Sbjct: 692 PSVGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKE--ISTLVSTTTTTSPTER 749 Query: 752 ---IAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKP----RQPTIDLSQ 804 + E +PT S + S + ++ A TT E + S P T S Sbjct: 750 MTLTSTENTPTSYILTTSPVTYSFSPSMSA--SSDWTTDTESISSAPAITSTLHTTAEST 807 Query: 805 MAVPIQMTQEKRHSPESPSIAVV-----ESELVAEYIT-------TERTDEGTEVAFPLL 852 +A + + E PS AV +S + T T TD TE + Sbjct: 808 LAPTTTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFMTPM 867 Query: 853 VSHRSQPQQPSQPQR---TLLQHVAQSQTATQT-SVVVKSIPASSPGAITHIMQQALSSH 908 +S + P S R T + A T T T S + SI +S+P T ++ ++ Sbjct: 868 IS--TTPITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSILSSTPVPSTEVITSQTTNT 925 Query: 909 TA 910 T+ Sbjct: 926 TS 927 Score = 65.9 bits (159), Expect = 3e-10 Identities = 196/1007 (19%), Positives = 351/1007 (34%), Gaps = 181/1007 (17%) Query: 241 MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300 +S+++ S ++ P K+ T P+ TT+ V ++F+ I + Sbjct: 88 LSSLVSSNTSTTPTSKFAFKVETTPPTVLVYLATTECVY------PTSFIITISHPTSIC 141 Query: 301 AAVTKLVPTSVIAST--TQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS 358 T++ TS T TQKP V T +++ ++ + G+S+ SP T T +V+ Sbjct: 142 VTTTQVTFTSSYTPTPVTQKP--VTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVTV 199 Query: 359 TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418 TPS S+V+ +T ++ST + Sbjct: 200 TPS---SSVSATDTTFHTTISST-----------------------------------TR 221 Query: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478 T ++ P+ H SP P + T++ S I + + + T + P Sbjct: 222 TTERTPLPTGSIH---TTMSPTP--VFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRP 276 Query: 479 TSSNSPIMVVSSNGAIMTTKLVTTPT-GTQATYTRPTVSPSIGRMAAT-PGAATYVKTTS 536 T++N + ++M+ L +TP T+ T + T + + + T P T TS Sbjct: 277 TATN-------TLSSLMSNILSSTPVPSTEMTTSHTTDTNPLSTLVTTLPTTITRSTPTS 329 Query: 537 GSIITVVPKSLAT-LGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLP 595 + P S T +I S +++GT + TT+P TS Q+TT T P Sbjct: 330 ETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSS-----QQTTETPMT----P 380 Query: 596 GKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTK 655 +VTT + ++ + + T+T I+ + T T+ + I+PT Sbjct: 381 TTKLVTTTTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPT-----SGTMVTSTNIVPT- 434 Query: 656 IVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQN 715 +KP+ + + V +Q Q Q + S E Sbjct: 435 ----------ADLKPELILLE---VHDQRIQAKNPRYSQTPFTSSTATS------PETTT 475 Query: 716 YTDSSSSSTESSQSSQDS-QPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATS 774 T ++ STES ++ S PV+ I + S A + T ++S S+T Sbjct: 476 LTCTNDISTESLTTAMTSTTPVISAITPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTP 535 Query: 775 TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAE 834 + TT + P + A+ + P SP+ V +S Sbjct: 536 APNTEVITSHTTT-----TTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTDSMTEIT 590 Query: 835 YITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSP 894 Y T+ T PL + + P L T T+T+ S P+ + Sbjct: 591 YSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNL------GNTTTETT--SHSTPSFTS 642 Query: 895 GAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKL 954 AI + + ++ ++F S G + T++P S T + + + Sbjct: 643 SAIYSTVNISTTTISSFPPSS-------GTMVTFTTMNPS------SLSTDISTTTLKNI 689 Query: 955 SQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQP 1014 +QP + T T T+ + P P SI++++++ L Sbjct: 690 TQPSVGSTGFLTAATDLTST---FTVSSSSAMSTSVTPSAP--SIQNKEISTLVSTTTTT 744 Query: 1015 KPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTP 1074 P +R T P + + + T P + + + Sbjct: 745 SP-----------TERMTLTSTENTPTSYILTTSPVTYSFSPSMSASSD------WTTDT 787 Query: 1075 QSQMSLPA--SSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPV 1132 +S S PA S+ TA P T + T +PP+ T G+ TS Sbjct: 788 ESISSAPAITSTLHTTAESTLAPTTTNSFT----TSANMEPPSTAVATTGTGQSTFTSST 843 Query: 1133 TSISPIQASEKTAVSDILKMSLMEAQIDT----------NVEHMIVDPPKKALATSMLTG 1182 + ++ + T +DI S M I T N + + T+ L+ Sbjct: 844 ATF--LETTTLTPTTDISTESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSS 901 Query: 1183 EAGSL------PSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 S+ PST ++ + N+T SPST+ ++L T Sbjct: 902 LTSSILSSTPVPSTEVITSQTTNTT-----------SPSTLVTTLPT 937 Score = 63.9 bits (154), Expect = 1e-09 Identities = 115/488 (23%), Positives = 208/488 (42%), Gaps = 65/488 (13%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +TA T T N + N + S P+ T S + + +T+T +S P SG++ T + Sbjct: 616 ETATTPTTN-LGNTTTE-TTSHSTPSFTSS--AIYSTVNISTTTISSFPPSSGTMVTFTT 671 Query: 169 PRPASPASNV-------VVLPS-GSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEV 220 P+S ++++ + PS GST ++ + + + ++SS+ S V Sbjct: 672 MNPSSLSTDISTTTLKNITQPSVGSTGFLTAAT-----DLTSTFTVSSSSAMSTSVTPSA 726 Query: 221 PKAV-VPVSKTITVPVSGSPKMSNIMQSIANSLPPHM---SPVKITFTKPSTQTTNTTTQ 276 P +S ++ + SP + S N+ ++ SPV +F+ + +++ TT Sbjct: 727 PSIQNKEISTLVSTTTTTSPTERMTLTSTENTPTSYILTTSPVTYSFSPSMSASSDWTTD 786 Query: 277 KVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQ---KPPVVITAS----QSS 329 T S SS P I S H A T L PT+ + TT +PP A+ QS+ Sbjct: 787 -----TESISSA--PAITSTLHTTAEST-LAPTTTNSFTTSANMEPPSTAVATTGTGQST 838 Query: 330 LVSNSSSGSSSSTPSP---IPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP 386 S++++ ++T +P I +T ++S+TP + S++ + +++ A++R + Sbjct: 839 FTSSTATFLETTTLTPTTDISTESFMTPMISTTP--ITSSMTLRNTMTSMTTAASRPTTT 896 Query: 387 KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKP 446 +L S + IL+ P + Q + P+ ++ P + Sbjct: 897 NTLSSLTSSILSSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTST--------PTSET 948 Query: 447 TIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVS--SNGAIMT-TKLVTTP 503 T S V T + S +T TL T + P S + G MT T+ + T Sbjct: 949 TYSTSPTSTVTDSTTETTYST----SITGTLSTEISLPATTSSLITKGISMTSTRNLVTT 1004 Query: 504 TGTQATYTRPTVSPSIGRMAATPGAA-TYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562 T +++ PT + +I +T A + V TTSG I+T + ++L I Sbjct: 1005 TNENTSHSTPTFTLTIHSTISTSTTAISSVPTTSGPIVTSTTMTPSSLTADI-------- 1056 Query: 563 TTTKITTI 570 TT +TTI Sbjct: 1057 PTTTLTTI 1064 Score = 40.0 bits (92), Expect = 0.015 Identities = 114/574 (19%), Positives = 198/574 (34%), Gaps = 74/574 (12%) Query: 753 AMETSP-TIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQP----TIDLSQMAV 807 AM +SP T ++ + + +S++ A TT+ + R P +I + Sbjct: 181 AMISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPT 240 Query: 808 PIQMTQEKRHSPESPSIAVVES-ELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQ 866 P+ T + + SP + + S V TT T L+ + S PS Sbjct: 241 PVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTLSSLMSNILSSTPVPSTEM 300 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T + + S +V ++P T I + +S T + T Sbjct: 301 TT-----SHTTDTNPLSTLVTTLP-------TTITRSTPTSETTYPASPTSTVT------ 342 Query: 927 EMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQ 986 D T + Y + LT + S + PP +Q +T TK T Q Sbjct: 343 -----DSTTEITYSTVLTGTLSPTT---TLPPTSSSQQTTETPMTPTTKLVTTTTETTSQ 394 Query: 987 LQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQV 1046 S T + + T MV +PT +P +++V Sbjct: 395 SSLNFSSSAIYSTVSTSTTAISS--------LPPTSGTMVTSTNIVPTADLKPELILLEV 446 Query: 1047 LAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVE-QPIITQGSSVTK 1105 + + P+ Q P P+T + S+E T + P+I S++T Sbjct: 447 HDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVI---SAITP 503 Query: 1106 ITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEH 1165 T TVT +T +S P T+ ++S++ S IL S + H Sbjct: 504 KT-------TVTSMTTTASGPTTTNTLSSLT----------SSILS-STPAPNTEVITSH 545 Query: 1166 MIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPST-VGSSLTTR 1224 P L T++ T A S P++ T + S+ T S+ TT Sbjct: 546 TTTTTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTDSMTEITYSTSMTGTWSTATTL 605 Query: 1225 KIDPPAVP----ATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGL 1280 + ++P AT + N + S AI Y+ S++ + P Sbjct: 606 PLTSCSLPTIETATTPTTNLGNTTTETTSHSTPSFTSSAI--YSTVNISTTTISSFPPSS 663 Query: 1281 LELNNFTSQQLDDEETAMEQDIDSST-EDGTEPS 1313 + FT+ +++ DI ++T ++ T+PS Sbjct: 664 GTMVTFTTM----NPSSLSTDISTTTLKNITQPS 693 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 83.6 bits (205), Expect = 1e-15 Identities = 142/692 (20%), Positives = 229/692 (33%), Gaps = 88/692 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3634 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3693 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3732 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3733 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3792 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3793 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3847 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3848 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3900 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3901 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3949 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3950 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P + + P Sbjct: 4064 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP------ITTTTTVTP 4117 Query: 654 TKIVYGQQGKTQVLIKPKPVTFQATVVSEQT-RQLVTETLQQASRVAEAGNSSIQEGKEE 712 T G Q T P+T TV T T T + + G + Sbjct: 4118 TPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4172 Query: 713 PQN--YTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSS--- 767 P T +++ + + + + P H + + + E+S + SS Sbjct: 4173 PTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT 4232 Query: 768 ESQSATSTIKALLELQQTTVKEKLESKPRQPT 799 ES + ST+ +E+ T S P PT Sbjct: 4233 ESTTLLSTLPPAIEMTSTAP----PSTPTAPT 4260 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 1909 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1967 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 1968 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2007 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2008 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2067 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2122 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2123 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2175 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2224 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2225 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2278 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2338 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2339 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2398 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2399 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2439 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 1978 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2036 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2037 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2076 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2077 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2137 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2191 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2192 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2244 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2293 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2294 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2347 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2407 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2408 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2467 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2468 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2508 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2047 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2105 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2106 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2145 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2260 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2261 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2313 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2314 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2362 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2363 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2416 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2536 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2537 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2577 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2116 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2174 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2175 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2214 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2215 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2275 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2329 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2330 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2383 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2431 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2432 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2485 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2545 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2546 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2605 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2606 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2646 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2185 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2243 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2244 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2283 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2284 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2343 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2344 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2398 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2399 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2500 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2501 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2554 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2674 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2675 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2254 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2313 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2352 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2353 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2412 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2413 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2467 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2468 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2521 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2569 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2570 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2623 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2624 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2683 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2684 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2743 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2744 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2784 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2323 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2382 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2421 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2481 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2482 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2536 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2537 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2589 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2590 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2638 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2639 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2692 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2753 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2812 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2813 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2853 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2392 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2451 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2490 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2491 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2550 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2551 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2605 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2606 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2659 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2707 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2708 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2761 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2762 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2821 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2822 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2881 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2882 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2922 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2461 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2520 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2559 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2674 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2675 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2727 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2728 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2776 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2777 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2830 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2891 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2950 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 2951 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2991 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2530 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2589 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2628 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2629 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2743 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2744 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2796 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2797 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2845 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2846 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2899 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3019 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3020 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3060 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2599 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2658 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2697 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2698 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2757 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2812 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2813 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2865 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2866 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2914 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2915 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2968 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3028 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3029 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3088 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3089 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3129 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2668 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2727 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2766 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2767 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2881 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2882 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 2935 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2983 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 2984 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3037 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3098 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3157 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3158 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2737 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2796 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2835 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2836 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2895 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2950 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 2951 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3003 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3052 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3053 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3106 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3166 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3167 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3226 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3227 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3267 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2806 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2865 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2904 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2905 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3019 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3020 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3072 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3121 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3122 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3175 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3236 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3295 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3296 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3336 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2875 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 2934 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2973 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3088 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3089 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3141 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3142 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3190 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3191 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3244 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3364 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3365 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3405 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 2944 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3003 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3042 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3043 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3102 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3157 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3158 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3259 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3260 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3313 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3314 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3373 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3374 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3433 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3434 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3474 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3013 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3072 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3111 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3171 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3172 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3226 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3227 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3328 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3329 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3382 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3443 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3502 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3503 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3543 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3082 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3141 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3180 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3181 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3240 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3241 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3295 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3296 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3349 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3397 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3398 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3451 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3452 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3511 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3512 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3571 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3572 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3612 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3151 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3210 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3249 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3250 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3309 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3364 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3365 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3418 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3466 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3467 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3520 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3581 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3640 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3641 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3681 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3220 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3279 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3318 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3319 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3379 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3433 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3434 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3487 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3535 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3536 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3589 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3590 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3649 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3650 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3709 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3710 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3750 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3289 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3348 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3387 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3388 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3447 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3502 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3503 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3555 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3556 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3604 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3605 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3658 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3659 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3719 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3778 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3779 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3819 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3358 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3417 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3456 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3457 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3517 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3571 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3572 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3625 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3673 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3674 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3727 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3728 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3788 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3847 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3848 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3888 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3427 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3486 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3525 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3526 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3585 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3586 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3640 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3641 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3693 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3694 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3742 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3743 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3796 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3916 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3917 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3957 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3496 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3555 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3594 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3595 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3654 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3655 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3709 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3710 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3762 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3763 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3811 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3812 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3865 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3926 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3985 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 3986 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4026 Score = 82.4 bits (202), Expect = 3e-15 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3565 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3623 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3624 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3663 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 3664 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3723 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 3724 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3778 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 3779 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3831 Query: 428 PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 P++ +P P G + PT T + + P P T + +PI Sbjct: 3832 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3880 Query: 487 VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546 + T TPTGTQ T P + + TP TT + T V + Sbjct: 3881 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3934 Query: 547 LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3994 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653 VT G +T T P + P T+ T P +TV P Sbjct: 3995 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4054 Query: 654 TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T+ T + P P T T T VT T Sbjct: 4055 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4095 Score = 82.0 bits (201), Expect = 3e-15 Identities = 139/653 (21%), Positives = 220/653 (33%), Gaps = 74/653 (11%) Query: 101 PLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 P P P T T + P+ + + + S +T T+TP P+ Sbjct: 1477 PSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536 Query: 161 GSIATVKSP---RPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL 217 T SP P +P ++ LP +T + + T ++ S P + Sbjct: 1537 ----TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTIT 1592 Query: 218 KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQK 277 P S T + P + + PP + T PS T TTT Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652 Query: 278 VIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS---TTQKPPVVI------TASQS 328 TT+PS P + S T PT+ +S TT PP T + S Sbjct: 1653 ---PTTTPSP---PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706 Query: 329 SLVSNSSSGSSSSTPSPIPNTVAVTA--VVSSTPSVVMSTVAQGVSTSAIKMASTRLP-- 384 S ++ +++ SS++TPSP P T+ + S P+ M+T+ +T++ + +T LP Sbjct: 1707 SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP--TTTSSPLTTTPLPPS 1764 Query: 385 ------SPKSLVSAPTQIL----------AQFPKQHQQSPKQQL--------YQVQQQTQ 420 SP S + T + + P H+ +L + + Sbjct: 1765 ITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCR 1824 Query: 421 QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIIT------QQVQPSKILPKPVT 474 + P+ Q + G+ + ++ GV + VQ + + +P T Sbjct: 1825 ATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTT 1884 Query: 475 ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534 T T+ N + T TPTGTQ T P + + TP T Sbjct: 1885 MTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1944 Query: 535 TSGSIITVVPKSLATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQK 583 T + T V + G + ++ ++ TTT TT P+T+ V Sbjct: 1945 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2004 Query: 584 TTGKGT-TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGI 641 TG T T + VT G +T T P + P T+ T P Sbjct: 2005 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2064 Query: 642 GSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 +TV P T+ T + P P T T T VT T Sbjct: 2065 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2117 Score = 79.0 bits (193), Expect = 3e-14 Identities = 99/392 (25%), Positives = 141/392 (35%), Gaps = 48/392 (12%) Query: 147 TSTTSTPTSTPVPSGSIATVKSP----RPASPASNVVVLPSGSTVYVKSVSCSDEDEKPR 202 T+TT+TP T PS I T +P P+ P S P +T + + S P Sbjct: 1426 TTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS 1485 Query: 203 KRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262 T ++++ P P P + IT P S +LPP +P T Sbjct: 1486 P--PTTTTTTPPPTTTPSP----PTTTPITPPAS------------TTTLPPTTTPSPPT 1527 Query: 263 FTKPSTQTTNTTTQKVIIVTTSP-SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPV 321 T + T T + T P S+T +P + S T PT TT PP Sbjct: 1528 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT-----TTPSPPT 1582 Query: 322 VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMST-VAQGVSTSAIKMAS 380 T S ++ +++ ++TPSP P T T ++TPS +T + ST+ + + Sbjct: 1583 TTTPSPPTI--TTTTPPPTTTPSP-PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639 Query: 381 TRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-QQSP 439 T P P + + P P SP P P + P +P Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSP----------PITTTTTPPPTTTPSSPITTTP 1689 Query: 440 LPPGIKPTIQIKQESGVKIITQQVQPSKIL---PKPVTATL--PTSSNSPIMVVSSNGAI 494 PP T + IT PS P P T T PT++ SP + Sbjct: 1690 SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749 Query: 495 MTTKLVTTPTGTQATYTRPTVSPSIGRMAATP 526 TT T T + T PT SP TP Sbjct: 1750 TTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781 Score = 74.3 bits (181), Expect = 7e-13 Identities = 105/391 (26%), Positives = 144/391 (36%), Gaps = 56/391 (14%) Query: 226 PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK--------PSTQTTNTTT-- 275 P+ K IT P + S S +LPP +P T T PS T TTT Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTS-TTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP 1449 Query: 276 -----QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL 330 I TT+P T P+ + + + T PT +TT PP T S + Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPT----TTTTTPPPTTTPSPPTT 1505 Query: 331 VSNSSSGSS-----SSTPSPIPNTVAVTAVVSSTPSVVMST-VAQGVSTSAIKMASTRLP 384 + S+ ++TPSP P T T ++TPS +T + ST+ + +T P Sbjct: 1506 TPITPPASTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564 Query: 385 SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSP---VSHQQQPQQSPLP 441 P + + P P SP + T PSP + P +P P Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPP----TITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620 Query: 442 PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATL--PTSSNSPIMVVSSNGAIMTTKL 499 P P I + + PS P P T T PT++ SP + + I TT Sbjct: 1621 PTTTP---ITPPTSTTTLPPTTTPS---PPPTTTTTPPPTTTPSPPTTTTPSPPITTT-- 1672 Query: 500 VTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNI 559 TTP PT +PS + TP T TT T P S T S+ Sbjct: 1673 -TTPP--------PTTTPS-SPITTTPSPPTTTMTTPSP--TTTPSSPITTTTTPSSTTT 1720 Query: 560 VSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590 S T +TT T+ P+ TT TT Sbjct: 1721 PSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT 1751 Score = 72.8 bits (177), Expect = 2e-12 Identities = 103/429 (24%), Positives = 150/429 (34%), Gaps = 76/429 (17%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPA-SPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206 +T S PT+TP P + T P SP + P +T ++ Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT------------- 1443 Query: 207 TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKP 266 ++++ P P P+S T T P + +P PP +P T T P Sbjct: 1444 --TTTTPPPTTTPSP----PISTTTTPPPTTTPS------------PPTTTPSPPT-TTP 1484 Query: 267 STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS 326 S TT TTT + P++T P + ASTT PP T + Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTT-------------------PITPPASTTTLPP---TTT 1522 Query: 327 QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP 386 S + +++ ++TPSP P T +T S+T +T + +T T P P Sbjct: 1523 PSPPTTTTTTPPPTTTPSP-PTTTPITPPTSTTTLPPTTTPSPPPTT-------TTTPPP 1574 Query: 387 KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPL-PPGIK 445 + S PT P +P T P P + P +P+ PP Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT--TTTTPPPTTTPSPPTTTPITPPTST 1632 Query: 446 PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTG 505 T+ T P P P T T P + PI ++ T T T Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP---SPPITTTTTPPPTTTPSSPITTTP 1689 Query: 506 TQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTT 565 + T T T SP+ TP + TT S T P T + S TT Sbjct: 1690 SPPTTTMTTPSPT-----TTPSSPITTTTTPSS--TTTPSPPPTTMTTPSPTTTPSPPTT 1742 Query: 566 KITTIPMTS 574 +TT+P T+ Sbjct: 1743 TMTTLPPTT 1751 Score = 72.8 bits (177), Expect = 2e-12 Identities = 126/589 (21%), Positives = 198/589 (33%), Gaps = 55/589 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPAS-PASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206 +TT +P +T PS I T +P P + P+S + PS T + + S + P Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT 1713 Query: 207 TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKP 266 T SS+++P P + T P + M+ + + +S P +P+ + T P Sbjct: 1714 TPSSTTTP----SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS-PLTTTPLPPSITPP 1768 Query: 267 STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV--------PTSVIASTTQK 318 + +TTT V + ++ + H T+L+ ++ T Sbjct: 1769 TFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMY 1828 Query: 319 PPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAV-------VSSTPSVVMSTVAQGV 371 P V I ++V + S G P V A V V T Sbjct: 1829 PDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTT 1888 Query: 372 ST-SAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVS 430 +T + +T + + ++ PT Q P + + T Q +P++ Sbjct: 1889 TTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1948 Query: 431 HQQQPQQSPLPPGIKP--TIQIKQESGVKIITQQVQPSKILPKPVTATL-------PTSS 481 +P P G + T I + V P+T T PT + Sbjct: 1949 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2008 Query: 482 NSPIMVVSSNGAIMTTKLVT---TPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGS 538 +P + I TT VT TPTGTQ T P + + TP TT + Sbjct: 2009 QTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063 Query: 539 IITVVPKSLATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGK 587 T V + G + ++ ++ TTT TT P+T+ V TG Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2123 Query: 588 GT-TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTV 645 T T + VT G +T T P + P T+ T P +TV Sbjct: 2124 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2183 Query: 646 QPAAKIIPTKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 P T+ T + P P T T T VT T Sbjct: 2184 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2232 Score = 72.4 bits (176), Expect = 3e-12 Identities = 103/483 (21%), Positives = 171/483 (35%), Gaps = 61/483 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ T+TT T T TP P+G+ +P + P+G+ Sbjct: 3910 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3968 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + + T + + +P P++ T TV + +P Sbjct: 3969 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 4008 Query: 251 SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P+ T T T T T T T I TT+ + T P T Sbjct: 4009 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367 T T + P + ++ V+ + + + + TP+ P T T + TP T Sbjct: 4069 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 4123 Query: 368 AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427 Q +T+ I +T P+P T Q P + + T Q + Sbjct: 4124 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4176 Query: 428 PVSHQQQPQQSPLPPGIK--PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPI 485 P++ +P P G + P ++ T P P+ +T + S Sbjct: 4177 PITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTT 4236 Query: 486 MVVSSNGAIMTTKLV--TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV 543 ++ + AI T +TPT T T+SP + PG T TT+GS Sbjct: 4237 LLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR-GTTTGSSSAPT 4295 Query: 544 PKSLATLGGKIISSNIVSGTTTKITTIPM-TSKPNVIVVQKTTGKGTTIQGLPGKNVVTT 602 P ++ T TT+ T P S P++I +TTG ++ P ++ Sbjct: 4296 PSTVQTT------------TTSAWTPTPTPLSTPSII---RTTG----LRPYPSSVLICC 4336 Query: 603 LLN 605 +LN Sbjct: 4337 VLN 4339 Score = 72.0 bits (175), Expect = 4e-12 Identities = 123/579 (21%), Positives = 194/579 (33%), Gaps = 57/579 (9%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRP-ASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRR 205 T+T S PT+T PS I T +P P +P+S + PS T + + S + P Sbjct: 1654 TTTPSPPTTT-TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712 Query: 206 RTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265 T SS+++P P + T P + M+ + + +S P +P+ + T Sbjct: 1713 TTPSSTTTP----SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS-PLTTTPLPPSITP 1767 Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV--------PTSVIASTTQ 317 P+ +TTT V + ++ + H T+L+ ++ T Sbjct: 1768 PTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATM 1827 Query: 318 KPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAV-------VSSTPSVVMSTVAQG 370 P V I ++V + S G P V A V V T Sbjct: 1828 YPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTT 1887 Query: 371 VST-SAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429 +T + +T + + ++ PT Q P + + T Q +P+ Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1947 Query: 430 SHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV 488 + +P P G + PT T + + P P T + +PI Sbjct: 1948 TTTTTVTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTT 1996 Query: 489 SSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLA 548 + T TPTGTQ T P + + TP TT + T V + Sbjct: 1997 T------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2050 Query: 549 TLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGLPG 596 G + ++ ++ TTT TT P+T+ V TG T T + Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110 Query: 597 KNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIPTK 655 VT G +T T P + P T+ T P +TV P T+ Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2170 Query: 656 IVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 T + P P T T T VT T Sbjct: 2171 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2209 Score = 71.6 bits (174), Expect = 5e-12 Identities = 107/530 (20%), Positives = 176/530 (33%), Gaps = 54/530 (10%) Query: 188 YVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQS 247 Y +V C + +P T + + +P P++ T TV + +P + + Sbjct: 1869 YEINVQCCECVTQPTTMTTTTTENPTP-------PTTTPITTTTTVTPTPTPTGTQTPTT 1921 Query: 248 IANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + ++P + TT TT + T +P+ T P T + Sbjct: 1922 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVT 1977 Query: 308 PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS--------ST 359 PT T IT + + + + +G+ + T +PI T VT + +T Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2037 Query: 360 PSVVMSTVAQGVSTSAIKMASTR-LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418 P +TV + + + +T + + ++ PT Q P + + Sbjct: 2038 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2097 Query: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATL 477 T Q +P++ +P P G + PT T + + P P Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGT 2146 Query: 478 PTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG 537 T + +PI + T TPTGTQ T P + + TP TT Sbjct: 2147 QTPTTTPITTTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2200 Query: 538 SIITVVPKSLATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTG 586 + T V + G + ++ ++ TTT TT P+T+ V TG Sbjct: 2201 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2260 Query: 587 KGT-TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGST 644 T T + VT G +T T P + P T+ T P +T Sbjct: 2261 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2320 Query: 645 VQPAAKIIPTKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691 V P T+ T + P P T T T VT T Sbjct: 2321 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2370 Score = 70.5 bits (171), Expect = 1e-11 Identities = 75/324 (23%), Positives = 123/324 (37%), Gaps = 28/324 (8%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSP---RPASPASNVVVLPSGSTV 187 P P T S S +TT +P +T + T SP P +P ++ LP +T Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT- 1522 Query: 188 YVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQS 247 P T +++P P + P + T T+P + +P + Sbjct: 1523 ----------PSPPTTTTTTPPPTTTPSPPTTTP--ITPPTSTTTLPPTTTPSPP---PT 1567 Query: 248 IANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + PP +P T T PS T TTT + P++T + + + T + Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627 Query: 308 P----TSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVV 363 P T++ +TT PP T + + + S +++TPSP P T T ++TPS Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPP--TTTPSPPTTTTPSP-PITTTTTPPPTTTPSSP 1684 Query: 364 MSTVAQGVSTSAIKMASTRLP-SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQ 422 ++T +T+ + T P SP + + P+ P + T Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744 Query: 423 VAQPSPVSHQQQPQQSPLPPGIKP 446 P P + +PLPP I P Sbjct: 1745 TTLP-PTTTSSPLTTTPLPPSITP 1767 Score = 36.6 bits (83), Expect = 0.16 Identities = 48/236 (20%), Positives = 66/236 (27%), Gaps = 10/236 (4%) Query: 1005 TPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQ 1064 TP P T P PT PP T TT P + Sbjct: 1538 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP 1597 Query: 1065 PKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKI--TFEGRQPPTVTKITGG 1122 P P T + P + T S IT +S T + T PPT T Sbjct: 1598 PTTTPSPPTTTTTTPPPTT----TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653 Query: 1123 SSVPKLTSPVTSISPIQASEK----TAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ P + T PI + T S + + P T+ Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT 1713 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPAT 1234 + P + +TP + P+T S LTT + P P T Sbjct: 1714 TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPT 1769 Score = 33.1 bits (74), Expect = 1.8 Identities = 51/221 (23%), Positives = 65/221 (29%), Gaps = 40/221 (18%) Query: 1014 PKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQT 1073 P P + T P PT PP T TT P +P P T Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT----TTPIT 1509 Query: 1074 PQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVT 1133 P PAS+ + P T ++ T PPT T IT +S L P T Sbjct: 1510 P------PASTTTLPPTTTPSPPTTTTTTPPPTTTP--SPPTTTPITPPTSTTTL-PPTT 1560 Query: 1134 SISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMV 1193 + SP + T PP + T + P T Sbjct: 1561 TPSPPPTTTTT------------------------PPPTTTPSPPTTTTPS---PPTITT 1593 Query: 1194 VAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPAT 1234 +TP + P+T S TT I PP T Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634 Score = 32.0 bits (71), Expect = 4.0 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 10/60 (16%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 S STP+ TP PS S +P P+ P+S PS T K C D D PR+ T Sbjct: 4375 SCPSTPSPTPTPSKS-----TPTPSKPSST----PSKPTPGTKPPECPDFD-PPRQENET 4424 >gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] Length = 2639 Score = 81.3 bits (199), Expect = 6e-15 Identities = 118/505 (23%), Positives = 183/505 (36%), Gaps = 75/505 (14%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206 T+TT PT TP+ + + T +P P S S P +T V + P Sbjct: 1305 TTTTENPTPTPITTTTTVT-PTPTPTSTQSTTPT-PITTTTTVTPTPTPTGTQTPTTTPI 1362 Query: 207 TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKP 266 T +++ +P + T T V+ +P + T T Sbjct: 1363 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG------------------TQTPT 1404 Query: 267 STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS 326 ST T TTT + T +P+ T P + T + PT T P IT + Sbjct: 1405 STPITTTTT---VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQAPTPTAITTT 1457 Query: 327 QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP 386 + + + +G+ + T +PI T VT TP+ T Q + +AI +T P+ Sbjct: 1458 STVTPTPTPTGTQTPTTTPITTTTTVT----PTPT---PTGTQTPTPTAITTTTTVTPT- 1509 Query: 387 KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK- 445 PT Q P + + T Q P+P+S +P P G + Sbjct: 1510 ------PTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT 1563 Query: 446 ----PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSN-GAIMTTKLV 500 P + T P+ +L T PT +P S+ I TT V Sbjct: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTP--TPTSTKSTTVTPITTTTTV 1621 Query: 501 T---TPTGTQA-----TYTRPTVSPSIGRMAATPGAATYVKTTSGSIITV--VPKSLATL 550 T TPTGTQ T TV+P+ + G T+ T + +T P +T Sbjct: 1622 TATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTP 1681 Query: 551 GGKIISSNIVSGTTTKITTIP------MTSKPNVIVVQKTTGKGTTIQ----------GL 594 +S+ ++ +TT ++T+P T+ P+ TT G T+ G Sbjct: 1682 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT 1741 Query: 595 PGKNVVTTLLNAGGEKTIQTVPTGA 619 P + T +A T+QT T A Sbjct: 1742 PTRGTTTGSSSAPTPSTVQTTTTSA 1766 Score = 79.0 bits (193), Expect = 3e-14 Identities = 89/403 (22%), Positives = 145/403 (35%), Gaps = 38/403 (9%) Query: 264 TKPSTQTTNTT---TQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPP 320 T+P+T TT TT T I TT+ + T P + PT + +TT P Sbjct: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPT---------STQSTTPTPITTTTTVTPT 1348 Query: 321 VVITASQSSLVSNSSSGSS-SSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMA 379 T +Q+ + ++ ++ + TP+P T +++T +V + G T Sbjct: 1349 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---- 1404 Query: 380 STRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSP 439 ST + + ++ PT Q P + + T Q P+ ++ +P Sbjct: 1405 STPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTP 1464 Query: 440 LPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATL---------PTSSNSPIMVVSS 490 P G + + + P P T PT + +P + Sbjct: 1465 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTP-----T 1519 Query: 491 NGAIMTTKLVT---TPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSL 547 + I TT VT TPTGTQ P + + TP TT + T V + Sbjct: 1520 STPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1579 Query: 548 ATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAG 607 G + ++ +++ TTT T TS + V TT T P T++ Sbjct: 1580 TPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPIS 1639 Query: 608 GEKTIQTVPT----GAKPAILTATRPITKMIVTQPKGIGSTVQ 646 T+ PT P T+T PI ++ + P ST Q Sbjct: 1640 TTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQ 1682 Score = 73.2 bits (178), Expect = 2e-12 Identities = 93/433 (21%), Positives = 157/433 (36%), Gaps = 40/433 (9%) Query: 131 PVPAETGSKEVVCYSYTSTTS-----------TPTSTPVPSGSIATVKSPRPASPASNVV 179 P P TG++ T+TT+ TPTSTP+ + + T + Sbjct: 1370 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTT 1429 Query: 180 VLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSP 239 + + +TV + P T++ + +P P++ T TV + +P Sbjct: 1430 PITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1489 Query: 240 KMSNIMQSIANSLPPHMSPVKI---TFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSK 296 + A + ++P T T ST T TTT + T +P+ T P Sbjct: 1490 TGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTT---VTPTPTPTGTQTPTPTPI 1546 Query: 297 SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356 S T + PT T + P + ++ V+ + + + + TP+ + T T Sbjct: 1547 S----TTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTP 1600 Query: 357 SSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQ 416 + TP+ ST ++T+ T P+P PT I +P Sbjct: 1601 TPTPTSTKSTTVTPITTTT---TVTATPTPTG-TQTPTMIPISTTTTVTPTPTPTTGSTG 1656 Query: 417 QQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT 476 T A + ++ P +S P + T ES + T LP + T Sbjct: 1657 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST--------LPPAIEMT 1708 Query: 477 LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536 ++P +++G + +T T T TR T + S A TP V+TT+ Sbjct: 1709 STAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS--SSAPTPST---VQTTT 1763 Query: 537 GSIITVVPKSLAT 549 S T P L+T Sbjct: 1764 TSAWTPTPTPLST 1776 Score = 66.2 bits (160), Expect = 2e-10 Identities = 85/391 (21%), Positives = 138/391 (35%), Gaps = 48/391 (12%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 P P TG++ + T TTST T TP P+G+ +P + P+G+ Sbjct: 1439 PTPTPTGTQAPTPTAIT-TTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT----- 1492 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 + P T + + +P P++ T TV + +P + Sbjct: 1493 ------QTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546 Query: 251 SLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTS 310 S ++P + TT TT + T +P+ T P + T + PT Sbjct: 1547 STTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVL----ITTTTTMTPTP 1602 Query: 311 VIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQG 370 ST K V + ++ V+ + + + + TP+ IP + T + TP+ + Sbjct: 1603 TPTST--KSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTH 1660 Query: 371 VSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVS 430 ST+ I +T P P+S S P QT + + P Sbjct: 1661 TSTAPIAELTTSNPPPES--STP------------------------QTSRSTSSPLT-- 1692 Query: 431 HQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSS 490 + S LPP I+ T S T + P P T T P + + S Sbjct: 1693 -ESTTLLSTLPPAIEMT-STAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS 1750 Query: 491 NGAIMTTKLVTTPTGTQATYTRPTVSPSIGR 521 + A + + TT T P +PSI R Sbjct: 1751 SSAPTPSTVQTTTTSAWTPTPTPLSTPSIIR 1781 Score = 58.5 bits (140), Expect = 4e-08 Identities = 63/276 (22%), Positives = 110/276 (39%), Gaps = 29/276 (10%) Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGS----T 186 P P TG+ + + STT+T T TP P+G+ +P + P+G+ T Sbjct: 1531 PTPTPTGT-QTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589 Query: 187 VYVKSVSCSDEDEKPRKRRRTNSS--------SSSPVVLKEVPKAVVPVSKTITVPVSGS 238 V + + + P + T + +++P ++P+S T TV + + Sbjct: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649 Query: 239 PKMSNIMQSIANSLPPHMSPVKITFTKP----STQTTNTTTQKVIIVTTSPSSTFVPNIL 294 P + S P ++T + P ST T+ +T + +T+ ST P I Sbjct: 1650 PTTGSTGPPTHTSTAPI---AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE 1706 Query: 295 SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTA 354 S T PT+ T PP T S + ++ SSS +P P+TV T Sbjct: 1707 MTS-TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSS--APTPSTVQTTT 1763 Query: 355 VVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLV 390 + TP+ + + T+ ++ P P S++ Sbjct: 1764 TSAWTPTPTPLSTPSIIRTTGLR------PYPSSVL 1793 Score = 57.8 bits (138), Expect = 7e-08 Identities = 102/467 (21%), Positives = 160/467 (34%), Gaps = 88/467 (18%) Query: 308 PTSVIASTTQKP-PVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMST 366 PT++ +TT+ P P IT + + + + + + S+TP+PI T VT TP+ T Sbjct: 1300 PTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTP----TPT---PT 1352 Query: 367 VAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQP 426 Q +T+ I +T P+P T Q Sbjct: 1353 GTQTPTTTPITTTTTVTPTPTP------------------------------TGTQTPTT 1382 Query: 427 SPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486 +P++ +P P G + T + + P P T + +PI Sbjct: 1383 TPITTTTTVTPTPTPTGTQTPTS----------TPITTTTTVTPTPTPTGTQTPTTTPIT 1432 Query: 487 VVSSNGAIMTTKLVTTPTGTQA-TYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545 + T TPTGTQA T T T + ++ G T T + TV P Sbjct: 1433 TTT------TVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486 Query: 546 SLATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQG 593 T G + + ++ TTT T+ P+T+ V TG T T Sbjct: 1487 PTPT-GTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTP 1545 Query: 594 LPGKNVVTTLLNAGGEKTIQTVPTGAKPAIL-----TATRPITKMIVTQPKGIGSTVQPA 648 + VT G +T T P + T T+ T +++T + T P Sbjct: 1546 ISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPT 1605 Query: 649 AKIIPTKIVYGQQGKTQVLIKPKPVTFQA-TVVSEQTRQLVT------------ETLQQA 695 + T V T V P P Q T++ T VT T Sbjct: 1606 STKSTT--VTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTST 1663 Query: 696 SRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIAS 742 + +AE S+ PQ +SS TES+ P + + ++ Sbjct: 1664 APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST 1710 Score = 45.8 bits (107), Expect = 3e-04 Identities = 72/324 (22%), Positives = 112/324 (34%), Gaps = 28/324 (8%) Query: 470 PKPVTATLP-TSSNSPIMVVSSNGA-IMTTKLVT---TPTGTQATYTRPTVSPSIGRMAA 524 P P+T T T + +P S+ I TT VT TPTGTQ T P + + Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1372 Query: 525 TPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKI-----------TTIPMT 573 TP TT + T V + G + +S ++ TTT TT P+T Sbjct: 1373 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPIT 1432 Query: 574 SKPNVIVVQKTTG-KGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITK 632 + V TG + T + + VT G +T T P + P Sbjct: 1433 TTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1492 Query: 633 MIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQT-RQLVTET 691 T P I +T + PT G Q T P+T TV T T T Sbjct: 1493 QTPT-PTAITTT----TTVTPTPTPTGTQTPTST-----PITTTTTVTPTPTPTGTQTPT 1542 Query: 692 LQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHE 751 S + G + P +++++ + + +Q V+ + + Sbjct: 1543 PTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTP 1602 Query: 752 IAMETSPTIIYQDVSSESQSATST 775 T T + ++ + +AT T Sbjct: 1603 TPTSTKSTTVTPITTTTTVTATPT 1626 Score = 34.7 bits (78), Expect = 0.62 Identities = 43/203 (21%), Positives = 70/203 (34%), Gaps = 15/203 (7%) Query: 1033 PTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQV 1092 PT P T + T P Q P + + T + P S++ T + Sbjct: 1558 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--VLITTTTTMTPTPTPTSTKSTTVT-- 1613 Query: 1093 EQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKM 1152 PI T + T G Q PT+ I+ ++V +P T + TA Sbjct: 1614 --PITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPI----- 1666 Query: 1153 SLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCS 1212 A++ T+ P+ + +TS E+ +L ST M ++ P + + Sbjct: 1667 ----AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 1722 Query: 1213 SPSTVGSSLTTRKIDPPAVPATG 1235 S S + PP P G Sbjct: 1723 SGGHTLSPPPSTTTSPPGTPTRG 1745 Score = 32.0 bits (71), Expect = 4.0 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 10/60 (16%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 S STP+ TP PS S +P P+ P+S PS T K C D D PR+ T Sbjct: 1835 SCPSTPSPTPTPSKS-----TPTPSKPSST----PSKPTPGTKPPECPDFD-PPRQENET 1884 >gi|161019170 mucin 5AC [Homo sapiens] Length = 6207 Score = 80.9 bits (198), Expect = 8e-15 Identities = 124/525 (23%), Positives = 188/525 (35%), Gaps = 43/525 (8%) Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSV 192 P T SK S + T+ P T + S AT +P P+S LP +T V ++ Sbjct: 4762 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4821 Query: 193 SCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSL 252 S P + ++ + P S T + + + Sbjct: 4822 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4881 Query: 253 PPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVI 312 S T+ TT TTT T S+ IL++ A VT VPT Sbjct: 4882 ATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT--VPTGST 4939 Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 A+ + T S+ + + SS +TPS P T + ST + +T + Sbjct: 4940 ATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIP 4999 Query: 373 TSAIKMASTRL---PSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429 +S++ TRL +P + +S T + P+ S VA PS Sbjct: 5000 SSSLGTTWTRLSQTTTPTATMSTATP--SSTPETVHTSTVLTATATTTGATGSVATPSST 5057 Query: 430 SHQQQPQQSPLPPGIKPTIQIKQESGVKI-ITQQVQPSKILPKPVTATLPTSSNSPIMVV 488 PG T ++ + T P L P T P S+ S I Sbjct: 5058 ------------PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTT--PMSTMSTIHTS 5103 Query: 489 SSNGAIMT-TKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSL 547 S+ T T L TT T T+AT + T S ++G T T + TT+ + T S Sbjct: 5104 STPETTHTSTVLTTTATMTRATNSTATPSSTLG----TTRILTELTTTATT--TAATGST 5157 Query: 548 ATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTL---- 603 ATL + TT I T P T ++ T +T+ VVTT+ Sbjct: 5158 ATLSS--------TPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMP 5209 Query: 604 -LNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 A + TV T PA+L ++ P T + T + +T++P Sbjct: 5210 TATASTVPSSSTVGTTRTPAVLPSSLP-TFSVSTVSSSVLTTLRP 5253 Score = 80.5 bits (197), Expect = 1e-14 Identities = 123/565 (21%), Positives = 208/565 (36%), Gaps = 77/565 (13%) Query: 147 TSTTSTPTSTP----------------VPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190 TS+T+ P+STP +GS AT S +P V+ P+ + Sbjct: 4707 TSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATS 4766 Query: 191 SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250 S + S R T + K +V P+ + P+ + + + Sbjct: 4767 SKATSSSS----PRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMS 4822 Query: 251 SLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSST-FVPNILSKSHNYAAVTKLVPT 309 ++ P +P + T T + TT TT + T++PSST IL++ A T Sbjct: 4823 TIHPSSTP-ETTHTS-TVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGP 4880 Query: 310 SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQ 369 + S+T ++T ++ + +S+G S++TPS P T + S+T +V + T + Sbjct: 4881 TATPSSTPGTTWILTELTTTATTTASTG-STATPSSTPGTTWILTEPSTTATVTVPTGST 4939 Query: 370 GVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429 ++S A T P + + PT S Sbjct: 4940 ATASSTQATAGT--PHVSTTATTPT-----------------------------VTSSKA 4968 Query: 430 SHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVS 489 + P + P ++ T + I PS L T T + + +P +S Sbjct: 4969 TPSSSPGTATALPALRSTATTPTATSFTAI-----PSSSL--GTTWTRLSQTTTPTATMS 5021 Query: 490 SNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAA--TYVKTTSGSIITVVPKSL 547 + T + V T T AT T + S+ ++TPG A T V TT+ + T P S Sbjct: 5022 TATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS 5081 Query: 548 ATLGGKIISSNIVSGTTTKITTIPMTSKP------NVIVVQKTTGKGTTIQGLPGKNVVT 601 G ++ + +T ++TI +S P V+ T + T P + T Sbjct: 5082 P---GTALTPPTTTPMST-MSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGT 5137 Query: 602 TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ 661 T + T T A L++T P T I+T+P I + + P G Sbjct: 5138 TRILTELTTTATTTAATGSTATLSST-PGTTWILTEPSTIATVMVPTGSTATASSTLGTA 5196 Query: 662 GKTQVL--IKPKPVTFQATVVSEQT 684 +V+ + P +TV S T Sbjct: 5197 HTPKVVTTMATMPTATASTVPSSST 5221 Score = 73.6 bits (179), Expect = 1e-12 Identities = 144/636 (22%), Positives = 237/636 (37%), Gaps = 121/636 (19%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206 TS+T+TP+STP + I T ++ + A+ +GST ++ S P + Sbjct: 3560 TSSTATPSSTPGTTW-ILTEQTTAATTTAT------TGST----AIPSSTPGTAPPPKVL 3608 Query: 207 TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS-PVKITFTK 265 T+++++ + + P + T T+PV S +S A S P S + T T Sbjct: 3609 TSTATTPTATSSKATSSSSPRTAT-TLPV----LTSTATKSTATSFTPIPSFTLGTTGTL 3663 Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325 P TT T I +++P +T +L+ A T+ + S+T ++T Sbjct: 3664 PEQTTTPMATMSTIHPSSTPETTHTSTVLTTK---ATTTRATSSMSTPSSTPGTTWILTE 3720 Query: 326 SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPS 385 ++ + +++G ++TPS P T + S+T +V + T + ++S A T Sbjct: 3721 LTTAATTTAATG-PTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTL--- 3776 Query: 386 PKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK 445 K L S T P+ +S + P SP Sbjct: 3777 -KVLTSTAT------------------------------TPTVISSRATPSSSPGTATAL 3805 Query: 446 PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMT-TKLVTTPT 504 P ++ TAT PT+++ + SS G T TTPT Sbjct: 3806 PALR-----------------------STATTPTATSVTAIPSSSLGTAWTRLSQTTTPT 3842 Query: 505 GTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTT 564 T +T T P+ +P + T +GS+ T P S G ++ + + TT Sbjct: 3843 ATMSTAT-PSSTPETVHTSTVLTTTTTTTRATGSVAT--PSSTP---GTAHTTKVPTTTT 3896 Query: 565 TKITTIPMTS-----KPNVIVVQKTT----GKGTTIQGLPGKNVVTTLLNAGGEKTIQTV 615 T T P +S P V + TT G T +PG T+L T TV Sbjct: 3897 TGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT----TTTTV 3952 Query: 616 PTG--AKPAILTATRPIT-------KMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQV 666 TG A P+ T T T T + + + + T G G T + Sbjct: 3953 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI 4012 Query: 667 LIKPKPVTFQATVVSEQTRQLVTETLQQ---ASRVAEA----GNSSIQEGKEEPQNYTDS 719 +P VT + T Q T L +SR E+ G ++ + + + Sbjct: 4013 -TEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATA 4071 Query: 720 SSSSTESS---QSSQDSQPVVHVIASRRQD---WSE 749 + S T +S SS S P+ V+ + + WSE Sbjct: 4072 TPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSE 4107 Score = 68.6 bits (166), Expect = 4e-11 Identities = 131/569 (23%), Positives = 199/569 (34%), Gaps = 55/569 (9%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P P T + +T A S +P+ T TST +TPT+T S Sbjct: 3566 PSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTAT---SSKA 3622 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223 + SPR A+ LP ++ KS + S P ++ + P + Sbjct: 3623 TSSSSPRTAT------TLPVLTSTATKSTATSFT---PIPSFTLGTTGTLP------EQT 3667 Query: 224 VVPVSKTITVPVSGSPKM---SNIMQSIANSLPPHMSPVKITFTKPSTQ-----TTNTTT 275 P++ T+ S +P+ S ++ + A + S + T +T TT TT Sbjct: 3668 TTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3727 Query: 276 QKVIIVTTSPSSTFVPN-ILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334 T +PSST IL++ A VT ++ AS+T+ + S+ + + Sbjct: 3728 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3787 Query: 335 SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP---SPKSLVS 391 SS +TPS P T + ST + +T + +S++ A TRL +P + +S Sbjct: 3788 VI-SSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMS 3846 Query: 392 APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451 T + P+ S + VA PS PG T ++ Sbjct: 3847 TATP--SSTPETVHTSTVLTTTTTTTRATGSVATPSST------------PGTAHTTKVP 3892 Query: 452 QESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQ 507 + T P L PV T T PT+ S + S G T ++TT T T Sbjct: 3893 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTV 3952 Query: 508 AT--YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTT 565 AT P+ S TP TT G ++ P S T+ S+ TT Sbjct: 3953 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGR--SLPPSSPHTVRTAWTSATSGILGTT 4010 Query: 566 KITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILT 625 IT + TT T P + TT T G T Sbjct: 4011 HITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTAT 4070 Query: 626 ATRPITKMIVTQPKGIGSTVQPAAKIIPT 654 AT T+ P T P ++ T Sbjct: 4071 ATPSKTRTSTLLPS--SPTSAPITTVVTT 4097 Score = 65.5 bits (158), Expect = 3e-10 Identities = 102/418 (24%), Positives = 156/418 (37%), Gaps = 53/418 (12%) Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQ---KPPVV 322 PST T++T +++P +T+ IL++ A T ++ I S+T PP V Sbjct: 3555 PSTPATSSTATP----SSTPGTTW---ILTEQTTAATTTATTGSTAIPSSTPGTAPPPKV 3607 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T++ ++ + SS +SSS+P ++T V+ ST + +TS + S Sbjct: 3608 LTSTATTPTATSSKATSSSSPR-----------TATTLPVLTSTATKSTATSFTPIPSFT 3656 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 L + +L T +A H S + + T + + S P +P Sbjct: 3657 LGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRA-TSSMSTPSSTPGTT 3715 Query: 443 GIKPTIQIKQESGVKI---ITQQVQPSK--ILPKP---VTATLPTSSNSPIMVVSSNGAI 494 I + + T P IL +P T T+PT S + SS A Sbjct: 3716 WILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTA---TASSTRAT 3772 Query: 495 MTTKLVTTPTGTQATY--TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVP-KSLATLG 551 T V T T T T +R T S S G A P + T + + +T +P SL T Sbjct: 3773 AGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAW 3832 Query: 552 GKIISSNIVSGTTTKITTIPMTSKPNV---------IVVQKTTGKGTTIQGLPG---KNV 599 ++ S + T T T P ++ V + TG T PG Sbjct: 3833 TRL--SQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTK 3890 Query: 600 VTTLLNAGGEKTIQTVP-TGAKPA--ILTATRPITKMIVTQPKGIGSTVQPAAKIIPT 654 V T G T + P T P I T T P T+ P I T A + T Sbjct: 3891 VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTT 3948 Score = 64.3 bits (155), Expect = 7e-10 Identities = 180/866 (20%), Positives = 307/866 (35%), Gaps = 128/866 (14%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P P+TA T T + S+ P+ T T+TT+ T T PS S Sbjct: 4352 PSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVT--PSSSP 4409 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223 T ++P P ++ SGSTV SV + T ++ S Sbjct: 4410 GTARTP-PVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGS---------M 4459 Query: 224 VVPVSKTITVPVSGSPKMSNIMQSI-ANSLPPHMSP--VKITFTKPSTQTTNTTTQKVII 280 P S T T + +P + N + SL P SP V+ +T ++ T TT + Sbjct: 4460 ATPSSSTQTSGTTHTPPVPNTTATTHGRSLSP-SSPHTVRTAWTSATSGTLGTT--HITE 4516 Query: 281 VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340 +T S T + H+ A++ P+S TT+ PP T + + S + +++ Sbjct: 4517 PSTGTSHTPAATTGTTQHSTPALSSPHPSS---RTTESPPSPGTTTPGHTTATSRT-TAT 4572 Query: 341 STPSPIPNTVAVTAVVSSTP--SVVMSTVAQGVSTSAIKMASTRLPSPK-------SLVS 391 +TPS + + + +S P +VV + + S S +P P S + Sbjct: 4573 ATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 4632 Query: 392 APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451 A + + P + + + Q P+ Q + L G+ + + Sbjct: 4633 AAGGAVCEQP-------------LGLECRAQAQPGVPLGELGQVVECSLDFGL--VCRNR 4677 Query: 452 QESG---------VKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502 ++ G +++ P + +P+S+ +++ + TT T Sbjct: 4678 EQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTE---LTTTATTTA 4734 Query: 503 PTGTQAT-------------YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLAT 549 TG+ AT T P +P+ AT ++ TT + + KS AT Sbjct: 4735 STGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTAT 4794 Query: 550 LGGKIISSNI-VSGTTTKITTIPM--------------TSKPNVIVVQKTTGKGT----T 590 I SS + +GT + TT P+ T V+ + TT + T T Sbjct: 4795 SVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTST 4854 Query: 591 IQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKM--IVTQPKGIGSTVQPA 648 PG + T L T T PT + T +T++ T GST P+ Sbjct: 4855 PSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS 4914 Query: 649 AKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQE 708 + G T +L +P T TV + T +S A AG + Sbjct: 4915 S----------TPGTTWILTEPS-TTATVTVPT-------GSTATASSTQATAGTPHVST 4956 Query: 709 GKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEI---AMETSPTIIYQDV 765 P SS ++ SS + + P + A+ S I ++ T+ T + Q Sbjct: 4957 TATTPT--VTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTT 5014 Query: 766 SSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIA 825 + + +T+T + E T+ + + T +A P +P + Sbjct: 5015 TPTATMSTATPSSTPETVHTST---VLTATATTTGATGSVATP-------SSTPGTAHTT 5064 Query: 826 VVESELVAEYITTERTDEGTEVAFPLL--VSHRSQPQQPSQPQRTLLQHVAQSQTATQTS 883 V + + T + GT + P +S S S P+ T V + TAT T Sbjct: 5065 KVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVL-TTTATMTR 5123 Query: 884 VVVKSIPASSPGAITHIMQQALSSHT 909 + SS T I+ + ++ T Sbjct: 5124 ATNSTATPSSTLGTTRILTELTTTAT 5149 Score = 63.5 bits (153), Expect = 1e-09 Identities = 90/391 (23%), Positives = 155/391 (39%), Gaps = 48/391 (12%) Query: 108 PQTAFTVT----ANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P T TVT + A A++ +L V T + V S+ +TP+S+P + ++ Sbjct: 3750 PSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVI----SSRATPSSSPGTATAL 3805 Query: 164 ATVKSPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVP 221 ++S A++V +PS S T + + + P T + SS+P + V Sbjct: 3806 PALRSTATTPTATSVTAIPSSSLGTAWTRL----SQTTTPTATMSTATPSSTP---ETVH 3858 Query: 222 KAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIV 281 + V + T T +GS + A H + V T T T T +++ + Sbjct: 3859 TSTVLTTTTTTTRATGSVATPSSTPGTA-----HTTKVPTTTTTGFTATPSSSPGTALTP 3913 Query: 282 TTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSS 341 S+T P + +++ T+ + +TT V T S ++ S++ + ++ Sbjct: 3914 PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT--TVATGSMATPSSSTQTSGTTH 3971 Query: 342 TPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFP 401 TP P+PNT A T S PS + S ++ + +T + P S V++ T Sbjct: 3972 TP-PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP-STVTSHTPAATTST 4029 Query: 402 KQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQ 461 QH + ++ P P S + +SP PG T G T Sbjct: 4030 TQH--------------STPALSSPHPSS---RTTESPPSPG---TTTPGHTRGTSRTTA 4069 Query: 462 QVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 PSK + + PTS +PI V + G Sbjct: 4070 TATPSKTRTSTLLPSSPTS--APITTVVTTG 4098 Score = 63.5 bits (153), Expect = 1e-09 Identities = 99/429 (23%), Positives = 161/429 (37%), Gaps = 63/429 (14%) Query: 260 KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKP 319 K+T T +T++T +T +++P +T+ IL++ A VT VPT A+ + Sbjct: 4223 KLTTTATTTESTGSTATP----SSTPGTTW---ILTEPSTTATVT--VPTGSTATASSTQ 4273 Query: 320 PVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMA 379 T S+ + + SS +TP P T + ST + +T + +S++ Sbjct: 4274 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 4333 Query: 380 STRL---PSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQ 436 TRL +P + +S T + P+ S + VA PS Sbjct: 4334 WTRLSQTTTPTATMSTATP--SSTPETAHTSTVLTTTATTTRATGSVATPSST------- 4384 Query: 437 QSPLPPGIKPTIQIKQESGVKI-ITQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNG 492 PG T ++ + +T P PV T T PT+S S + S G Sbjct: 4385 -----PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 4439 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT-VVPKSLATLG 551 T ++TT T T AT G M ATP ++T TSG+ T VP + AT Sbjct: 4440 TTHTPTVLTTTTTTVAT----------GSM-ATPSSST---QTSGTTHTPPVPNTTATTH 4485 Query: 552 GKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKT 611 G+ +S + T T+ + + + +TG T G +T + + Sbjct: 4486 GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 4545 Query: 612 IQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPK 671 +T + P T P +T + A P+K +T L+ Sbjct: 4546 SRTTESPPSPG------------TTTPGHTTATSRTTATATPSKT------RTSTLLPSS 4587 Query: 672 PVTFQATVV 680 P + T V Sbjct: 4588 PTSAPITTV 4596 Score = 60.1 bits (144), Expect = 1e-08 Identities = 84/387 (21%), Positives = 151/387 (39%), Gaps = 40/387 (10%) Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK 167 P T T TA+ + A P + + + TS+ +TP+S+P + ++ ++ Sbjct: 2603 PTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALR 2662 Query: 168 SPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV 225 S A++V +PS S T + + + P T + SS+P + + V Sbjct: 2663 STATTPTATSVTPIPSSSLGTTWTR----LSQTTTPTATMSTATPSSTP---ETAHTSTV 2715 Query: 226 PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSP 285 + T +GS + A H + V T T T T +++ + Sbjct: 2716 LTATATTTGATGSVATPSSTPGTA-----HTTKVPTTTTTGFTATPSSSPGTALTPPVWI 2770 Query: 286 SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSP 345 S+T P + +++ T+ + +TT V T S ++ S++ + ++ TP P Sbjct: 2771 STTTTPTTRGSTVTPSSIPGTTHTATVLTTT--TTTVATGSMATPSSSTQTSGTTHTP-P 2827 Query: 346 IPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQ 405 +PNT+A T S PS + S ++ + +T + P S V++ T QH Sbjct: 2828 VPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP-STVTSHTLAATTGTTQH- 2885 Query: 406 QSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQP 465 + ++ P P S + +SP PG T + T P Sbjct: 2886 -------------STPALSSPHPSS---RTTESPPSPG---TTTPGHTTATSRTTATATP 2926 Query: 466 SKILPKPVTATLPTSSNSPIMVVSSNG 492 SK + + PTS +PI V + G Sbjct: 2927 SKTRTSTLLPSSPTS--APITTVVTMG 2951 Score = 58.5 bits (140), Expect = 4e-08 Identities = 182/854 (21%), Positives = 294/854 (34%), Gaps = 138/854 (16%) Query: 108 PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164 P T TVT + A + Q A P + T + V TS+ +TP S+P + ++ Sbjct: 4253 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPFSSPGTATALP 4308 Query: 165 TVKSPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPK 222 ++S A++ +PS S T + + + P T + SS+P + Sbjct: 4309 ALRSTATTPTATSFTAIPSSSLGTTWTR----LSQTTTPTATMSTATPSSTP---ETAHT 4361 Query: 223 AVVPVSKTITVPVSGSPKMSNIMQSIANSLP-PHMSPVKITFTKPSTQTTNTTTQKVIIV 281 + V + T +GS + A++ P + T T S+ T T I Sbjct: 4362 STVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIST 4421 Query: 282 TTSPS---STFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGS 338 TT+P+ ST P+ + T PT + +TT V T S ++ S++ + Sbjct: 4422 TTTPTTSGSTVTPSSVPG-------TTHTPTVLTTTTT----TVATGSMATPSSSTQTSG 4470 Query: 339 SSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILA 398 ++ TP P+PNT A T S +PS + S ++ + +T + P + S Sbjct: 4471 TTHTP-PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS------- 4522 Query: 399 QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKI 458 +P Q T ++ P P S + +SP PG T + Sbjct: 4523 -------HTPAATTGTTQHST-PALSSPHPSS---RTTESPPSPG---TTTPGHTTATSR 4568 Query: 459 ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQAT------YTR 512 T PSK + + PTS +PI T +VTT Q Y+ Sbjct: 4569 TTATATPSKTRTSTLLPSSPTS--API-----------TTVVTTGCEPQCAWSEWLDYSY 4615 Query: 513 PTVSPSIG------RMAATPGAATYVKTTSGSIITVVPKSLATLG--GKIISSNIVSGTT 564 P PS G + A GA + G + LG G+++ ++ G Sbjct: 4616 PMPGPSGGDFDTYSNIRAAGGAV--CEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLV 4673 Query: 565 TK----ITTIPMTSKPNVIVV---------QKTTGKGTTIQGLPGKNVVTTLLNAGGEKT 611 + + M + V T PG + T L T Sbjct: 4674 CRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTT 4733 Query: 612 IQTVPT-------GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKT 664 T T G P T P T T K S+ A +P + T Sbjct: 4734 ASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPV-LTSTATKST 4792 Query: 665 QVLIKPKPVTFQAT--VVSEQTRQLVT--ETLQQASRVAEAGNSSIQEGKEEPQNYTDSS 720 + P P + T + EQT V T+ +S S++ K T S+ Sbjct: 4793 ATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSST 4852 Query: 721 SSS-------------TESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSS 767 S+ T ++ ++ + P ++ W E+ T+ T S+ Sbjct: 4853 STPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELT--TTATTTASTGST 4910 Query: 768 ESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVV 827 + S+T +L TT + P T S TQ +P + A Sbjct: 4911 ATPSSTPGTTWILTEPSTTATVTV---PTGSTATASS-------TQATAGTPHVSTTATT 4960 Query: 828 ESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPS---QPQRTL-LQHVAQSQTATQTS 883 + V T + GT A P L S + P S P +L SQT T T+ Sbjct: 4961 PT--VTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 5018 Query: 884 VVVKSIPASSPGAI 897 + + P+S+P + Sbjct: 5019 TMSTATPSSTPETV 5032 Score = 58.2 bits (139), Expect = 5e-08 Identities = 98/427 (22%), Positives = 150/427 (35%), Gaps = 87/427 (20%) Query: 322 VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381 V+ S ++ + SS++TPS P T + ++T + ST + TS ++ A Sbjct: 2569 VLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTA-- 2626 Query: 382 RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLP 441 P PK L + T P+ S + P SP Sbjct: 2627 --PPPKVLTTTAT------------------------------TPTVTSSKATPSSSPGT 2654 Query: 442 PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMT-TKLV 500 P ++ TAT PT+++ + SS G T Sbjct: 2655 ATALPALR-----------------------STATTPTATSVTPIPSSSLGTTWTRLSQT 2691 Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TTPT T +T T P+ +P A T T TT+G+ +V S + G ++ + Sbjct: 2692 TTPTATMSTAT-PSSTP---ETAHTSTVLTATATTTGATGSVATPS--STPGTAHTTKVP 2745 Query: 561 SGTTTKITTIPMTS-----KPNVIVVQKTT----GKGTTIQGLPGKNVVTTLLNAGGEKT 611 + TTT T P +S P V + TT G T +PG T+L T Sbjct: 2746 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT----T 2801 Query: 612 IQTVPTG--AKPAILTATRPIT-------KMIVTQPKGIGSTVQPAAKIIPTKIVYGQQG 662 TV TG A P+ T T T M T + + + + T G G Sbjct: 2802 TTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILG 2861 Query: 663 KTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSS 722 T + +P VT + T Q T L + S G P + T +S + Sbjct: 2862 TTHI-TEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRT 2920 Query: 723 STESSQS 729 + ++ S Sbjct: 2921 TATATPS 2927 Score = 57.4 bits (137), Expect = 9e-08 Identities = 97/419 (23%), Positives = 149/419 (35%), Gaps = 56/419 (13%) Query: 270 TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 TT TTT+ T S+ IL++ A VT VPT A+ + T S+ Sbjct: 3079 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVT--VPTGSTATASSTQATAGTPHVST 3136 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRL---PSP 386 + + SS +TP P T + ST + +T + +S++ TRL +P Sbjct: 3137 TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 3196 Query: 387 KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKP 446 + +S T + P+ S VA PS PG Sbjct: 3197 TATMSTATP--SSTPETVHTSTVLTTTATTTGATGSVATPSST------------PGTAH 3242 Query: 447 TIQIKQESGVKI-ITQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTKLVTT 502 T ++ + T P PV T T PT+ S + S G T ++TT Sbjct: 3243 TTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTT 3302 Query: 503 PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT-VVPKSLATLGGKIISSNIVS 561 T T AT G M ATP ++T TSG+ T VP + AT G+ +S + Sbjct: 3303 TTTTVAT----------GSM-ATPSSST---QTSGTTHTPPVPNTTATTHGRSLSPSSPH 3348 Query: 562 GTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKP 621 T T+ + + + +TG T G +T + + +T + P Sbjct: 3349 TVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP 3408 Query: 622 AILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 T P +T + A P+K +T L+ P + T V Sbjct: 3409 G------------TTTPGHTRATSRTTATATPSKT------RTSTLLPSSPTSAPITTV 3449 Score = 56.6 bits (135), Expect = 2e-07 Identities = 128/609 (21%), Positives = 213/609 (34%), Gaps = 85/609 (13%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P P+TA T T S+ P+ T T+TT+ T+T PS S Sbjct: 2703 PSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT--PSSSP 2760 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223 T +P P ++ GSTV S+ + T ++ S Sbjct: 2761 GTALTP-PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGS---------M 2810 Query: 224 VVPVSKTITVPVSGSPKMSNIMQSI-ANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVT 282 P S T T + +P + N M + SLPP SP + S + T + + Sbjct: 2811 ATPSSSTQTSGTTHTPPVPNTMATTHGRSLPP-SSPHTVRTAWTSATSGILGTTHITEPS 2869 Query: 283 TSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSST 342 T S T + H+ A++ P+S TT+ PP T + + S + ++++T Sbjct: 2870 TVTSHTLAATTGTTQHSTPALSSPHPSS---RTTESPPSPGTTTPGHTTATSRT-TATAT 2925 Query: 343 PSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP---------KSLVSAP 393 PS + + + +S P + T+ + + P P S + A Sbjct: 2926 PSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA 2985 Query: 394 TQILAQFP-------KQHQQSPKQQLYQVQQ---------QTQQQVAQPSPVSHQQ---- 433 + + P + P ++L QV + + ++QV + + + Sbjct: 2986 GGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVF 3045 Query: 434 --QPQQSPLPPGIKPTIQIKQESGVK-IITQQVQPSKILPKPVTATLPTSSNSPIMVVSS 490 P P T G I+T+ + + P+S+ +++ Sbjct: 3046 CCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTE 3105 Query: 491 NGAIMTTKLVTTPTGTQA----------------TYTRPTVSPSIGRMAATPGAATYV-- 532 TT VT PTG+ A T T PTV+ S ++PG AT + Sbjct: 3106 PS---TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPA 3162 Query: 533 -----KTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGK 587 T + + T +P S +LG + + T ++T +S P + Sbjct: 3163 LRSTATTPTATSFTAIPSS--SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT 3220 Query: 588 GTTIQGLPGKNVV--TTLLNAGGEKTIQTVPTG--AKPAI---LTATRPITKMIVTQPKG 640 T G G +T A K + T TG A P+ T P+ T P Sbjct: 3221 TATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTT 3280 Query: 641 IGSTVQPAA 649 GSTV P++ Sbjct: 3281 RGSTVTPSS 3289 Score = 56.2 bits (134), Expect = 2e-07 Identities = 94/423 (22%), Positives = 153/423 (36%), Gaps = 62/423 (14%) Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325 PST T++T +++P +T++ + + A T T T PP V+T Sbjct: 2579 PSTPATSSTATP----SSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 2634 Query: 326 SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP- 384 + ++ + SS +TPS P T + ST + +T + +S++ TRL Sbjct: 2635 TATT----PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQ 2690 Query: 385 --SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 +P + +S T + P+ S VA PS P Sbjct: 2691 TTTPTATMSTATP--SSTPETAHTSTVLTATATTTGATGSVATPSST------------P 2736 Query: 443 GIKPTIQIKQESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTK 498 G T ++ + T P L PV T T PT+ S + S G T Sbjct: 2737 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTAT 2796 Query: 499 LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT-VVPKSLATLGGKIISS 557 ++TT T T AT G M ATP ++T TSG+ T VP ++AT G+ + Sbjct: 2797 VLTTTTTTVAT----------GSM-ATPSSST---QTSGTTHTPPVPNTMATTHGRSLPP 2842 Query: 558 NIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPT 617 + T T+ + + +T T+ G +T + + +T + Sbjct: 2843 SSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTES 2902 Query: 618 GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677 P T P +T + A P+K +T L+ P + Sbjct: 2903 PPSPG------------TTTPGHTTATSRTTATATPSKT------RTSTLLPSSPTSAPI 2944 Query: 678 TVV 680 T V Sbjct: 2945 TTV 2947 Score = 55.8 bits (133), Expect = 3e-07 Identities = 87/390 (22%), Positives = 150/390 (38%), Gaps = 47/390 (12%) Query: 108 PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164 P T TVT + A + Q A P + T + V TS+ +TP S+P + ++ Sbjct: 3106 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPFSSPGTATALP 3161 Query: 165 TVKSPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPK 222 ++S A++ +PS S T + + + P T + SS+P + V Sbjct: 3162 ALRSTATTPTATSFTAIPSSSLGTTWTR----LSQTTTPTATMSTATPSSTP---ETVHT 3214 Query: 223 AVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVT 282 + V + T +GS + A H + V T T T T +++ + Sbjct: 3215 STVLTTTATTTGATGSVATPSSTPGTA-----HTTKVLTTTTTGFTATPSSSPGTARTLP 3269 Query: 283 TSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSST 342 S+T P + +++ T + +TT V T S ++ S++ + ++ T Sbjct: 3270 VWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTT--TTTVATGSMATPSSSTQTSGTTHT 3327 Query: 343 PSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPK 402 P P+PNT A T S +PS + S ++ + +T + P + S Sbjct: 3328 P-PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS----------- 3375 Query: 403 QHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQ 462 +P Q T ++ P P S + +SP PG + S T Sbjct: 3376 ---HTPAATTGTTQHST-PALSSPHPSS---RTTESPPSPGTTTPGHTRATSRT---TAT 3425 Query: 463 VQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 PSK + + PTS +PI V + G Sbjct: 3426 ATPSKTRTSTLLPSSPTS--APITTVVTMG 3453 Score = 55.8 bits (133), Expect = 3e-07 Identities = 92/432 (21%), Positives = 148/432 (34%), Gaps = 78/432 (18%) Query: 147 TSTTSTPTSTP--------VPSGSIATVKSPRPASPASN--------------VVVLPSG 184 TS+T+TP+STP + + + T + A+P+S V +P+G Sbjct: 4205 TSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 4264 Query: 185 STVYVKSVSCSDEDEKPRKRRRT---NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKM 241 ST S + T SS ++P A+ + T T P + S Sbjct: 4265 STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATS--- 4321 Query: 242 SNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYA 301 ++P S + T+T+ S TT T T +++P + +L+ + Sbjct: 4322 -------FTAIP--SSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTT 4372 Query: 302 AVTKLVPT-SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTP------SPIPNTVAVTA 354 T V T S T V T + V+ SSS ++ TP + P T T Sbjct: 4373 RATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTV 4432 Query: 355 VVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQ 414 SS P + +T+ + S PS + S T Sbjct: 4433 TPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTH------------------- 4473 Query: 415 VQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT 474 V + +H + SP P T SG T +PS Sbjct: 4474 -----TPPVPNTTATTHGR--SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 4526 Query: 475 ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534 AT T+ +S + S + + TT+ +P T +T T + T AT KT Sbjct: 4527 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTAT--------SRTTATATPSKT 4578 Query: 535 TSGSIITVVPKS 546 + +++ P S Sbjct: 4579 RTSTLLPSSPTS 4590 Score = 55.5 bits (132), Expect = 3e-07 Identities = 90/383 (23%), Positives = 143/383 (37%), Gaps = 40/383 (10%) Query: 297 SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356 ++ + T ++ + S+T ++T ++ + S+GS++ TPS P T + Sbjct: 3048 NYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTA-TPSSTPGTTWILTEP 3106 Query: 357 SSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQ 416 S+T +V + T + ++S A T P + + PT ++ L Sbjct: 3107 STTATVTVPTGSTATASSTQATAGT--PHVSTTATTPTVTSSKATPFSSPGTATAL---- 3160 Query: 417 QQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV--- 473 + P+ S P S + + + + T P + V Sbjct: 3161 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT 3220 Query: 474 TATLPTSSNSPIMVVSSNGAIMTTK-LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYV 532 TAT ++ S S+ G TTK L TT TG AT P+ SP R + T Sbjct: 3221 TATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTAT---PSSSPGTARTLPVWISTTTT 3277 Query: 533 KTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQ 592 TT GS TV P S+ G + +++ TTT + T M + + T GTT Sbjct: 3278 PTTRGS--TVTPSSIP---GTTHTPTVLTTTTTTVATGSMATPSS-----STQTSGTTHT 3327 Query: 593 GLPGKNVVTT---LLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAA 649 TT L+ T++T T A L T +T+P G++ PAA Sbjct: 3328 PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH------ITEP-STGTSHTPAA 3380 Query: 650 KIIPTKIVYGQQGKTQVLIKPKP 672 T Q T L P P Sbjct: 3381 TTGTT------QHSTPALSSPHP 3397 Score = 55.1 bits (131), Expect = 4e-07 Identities = 88/432 (20%), Positives = 146/432 (33%), Gaps = 78/432 (18%) Query: 147 TSTTSTPTSTP--------VPSGSIATVKSPRPASPASN--------------VVVLPSG 184 TS+T+ P+STP + + + T + A+P+S V +P+G Sbjct: 3058 TSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 3117 Query: 185 STVYVKSVSCSDEDEKPRKRRRT---NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKM 241 ST S + T SS ++P A+ + T T P + S Sbjct: 3118 STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATS--- 3174 Query: 242 SNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYA 301 ++P S + T+T+ S TT T T +++P + +L+ + Sbjct: 3175 -------FTAIP--SSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTT 3225 Query: 302 AVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPI-------PNTVAVTA 354 T V T T V+T + + + SS ++ P+ P T T Sbjct: 3226 GATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTV 3285 Query: 355 VVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQ 414 SS P + +T+ + S PS + S T Sbjct: 3286 TPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTH------------------- 3326 Query: 415 VQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT 474 V + +H + SP P T SG T +PS Sbjct: 3327 -----TPPVPNTTATTHGR--SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 3379 Query: 475 ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534 AT T+ +S + S + + TT+ +P T +TR T + T AT KT Sbjct: 3380 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRAT--------SRTTATATPSKT 3431 Query: 535 TSGSIITVVPKS 546 + +++ P S Sbjct: 3432 RTSTLLPSSPTS 3443 Score = 53.5 bits (127), Expect = 1e-06 Identities = 92/381 (24%), Positives = 138/381 (36%), Gaps = 38/381 (9%) Query: 299 NYAAVTKLVPTSVIASTTQKPPVV-ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS 357 NY TS A+ + P I ++ + + S S++TPS P T + S Sbjct: 4195 NYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPS 4254 Query: 358 STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQ 417 +T +V + T + ++S A T P + + PT ++ L Sbjct: 4255 TTATVTVPTGSTATASSTQATAGT--PHVSTTATTPTVTSSKATPFSSPGTATAL----P 4308 Query: 418 QTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV---T 474 + P+ S P S + + + + T P V T Sbjct: 4309 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 4368 Query: 475 ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534 AT ++ S S+ G TTK+ TT T T T T P+ SP R + T T Sbjct: 4369 ATTTRATGSVATPSSTPGTAHTTKVPTTTT-TGFTVT-PSSSPGTARTPPVWISTTTTPT 4426 Query: 535 TSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGL 594 TSGS TV P S+ G + +++ TTT + T M + + T GTT Sbjct: 4427 TSGS--TVTPSSVP---GTTHTPTVLTTTTTTVATGSMATPSS-----STQTSGTTHTPP 4476 Query: 595 PGKNVVTT---LLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651 TT L+ T++T T A L T +T+P G++ PAA Sbjct: 4477 VPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH------ITEP-STGTSHTPAATT 4529 Query: 652 IPTKIVYGQQGKTQVLIKPKP 672 T Q T L P P Sbjct: 4530 GTT------QHSTPALSSPHP 4544 Score = 53.1 bits (126), Expect = 2e-06 Identities = 177/869 (20%), Positives = 299/869 (34%), Gaps = 131/869 (15%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P P+T T T S+ P+ T T+TT+ T+T PS S Sbjct: 3205 PSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTAT--PSSSP 3262 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223 T ++ P ++ GSTV S+ + T ++ S Sbjct: 3263 GTART-LPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGS---------M 3312 Query: 224 VVPVSKTITVPVSGSPKMSNIMQSI-ANSLPPHMSP--VKITFTKPSTQTTNTTTQKVII 280 P S T T + +P + N + SL P SP V+ +T ++ T TT + Sbjct: 3313 ATPSSSTQTSGTTHTPPVPNTTATTHGRSLSP-SSPHTVRTAWTSATSGTLGTT--HITE 3369 Query: 281 VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340 +T S T + H+ A++ P+S TT+ PP T + + S + +++ Sbjct: 3370 PSTGTSHTPAATTGTTQHSTPALSSPHPSS---RTTESPPSPGTTTPGHTRATSRT-TAT 3425 Query: 341 STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP---------KSLVS 391 +TPS + + + +S P + T+ + + P P S + Sbjct: 3426 ATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 3485 Query: 392 APTQILAQFP-------KQHQQSPKQQLYQVQQ---------QTQQQVAQPSPVSHQQ-- 433 A + + P + P ++L QV + + ++QV + + + Sbjct: 3486 AAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 3545 Query: 434 ----QPQQSPLPPGIKPTIQIKQESGVK-IITQQVQPSKILPKPVTATLPTSSNSPIMVV 488 P P T G I+T+Q AT ++ S + Sbjct: 3546 VFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQT---------TAATTTATTGSTAIPS 3596 Query: 489 SSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLA 548 S+ G K++T +T T PT + S +++P A TT + + KS A Sbjct: 3597 STPGTAPPPKVLT------STATTPTATSSKATSSSSPRTA----TTLPVLTSTATKSTA 3646 Query: 549 TLGGKIISSNI-VSGTTTKITTIPM--------------TSKPNVIVVQKTTGKGT---- 589 T I S + +GT + TT PM T V+ + TT + T Sbjct: 3647 TSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMS 3706 Query: 590 TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAA 649 T PG + T L T T PT ++ P T I+T+P + P Sbjct: 3707 TPSSTPGTTWILTELTTAATTTAATGPTAT-----PSSTPGTTWILTEPSTTATVTVPTG 3761 Query: 650 KIIPTKIVYGQQGKTQVLIK----PKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSS 705 G +VL P ++ +AT S L+ + A + + Sbjct: 3762 STATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVT 3821 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSE--HEIAMETSPTIIYQ 763 SSS T ++ SQ + P + + E H + T+ T + Sbjct: 3822 A----------IPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTR 3871 Query: 764 DVSSESQSATSTIKALLELQQTTVKEKLESKPRQP--TIDLSQMAVPIQMTQEKRHSPES 821 S + +++ A TT + P T + + T R S + Sbjct: 3872 ATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVT 3931 Query: 822 PSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQ 881 PS ++ + A +TT T T + P +Q T + TAT Sbjct: 3932 PS-SIPGTTHTATVLTTTTTTVAT--------GSMATPSSSTQTSGTTHTPPVPNTTATT 3982 Query: 882 TSVVVKSIPASSPGAITHIMQQALSSHTA 910 +S+P SSP H ++ A +S T+ Sbjct: 3983 HG---RSLPPSSP----HTVRTAWTSATS 4004 Score = 44.7 bits (104), Expect = 6e-04 Identities = 58/253 (22%), Positives = 98/253 (38%), Gaps = 25/253 (9%) Query: 104 PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163 P P+T T T S+ P+ T T+TT+ T+T PS S Sbjct: 5025 PSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT--PSSSP 5082 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPV-----VLK 218 T +P +P S + + + ST S R ++++ S +L Sbjct: 5083 GTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILT 5142 Query: 219 EVPKAVVPVSKT-ITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQK 277 E+ + T T +S +P + I+ +++ M P T T ST T T + Sbjct: 5143 ELTTTATTTAATGSTATLSSTPGTTWILTE-PSTIATVMVPTGSTATASSTLGTAHTPKV 5201 Query: 278 VIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSN-SSS 336 V + T P++T VP+S TT+ P V+ ++ + VS SSS Sbjct: 5202 VTTMATMPTAT---------------ASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSS 5246 Query: 337 GSSSSTPSPIPNT 349 ++ P+ P++ Sbjct: 5247 VLTTLRPTGFPSS 5259 Score = 37.7 bits (86), Expect = 0.074 Identities = 47/185 (25%), Positives = 73/185 (39%), Gaps = 20/185 (10%) Query: 1065 PKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQP-PTVTKITGGS 1123 PK+ P T + S A+S + P++T S+ TK T P P+ T T G+ Sbjct: 4752 PKVLTSPATTPTATSSKATSSSSPRTATTLPVLT--STATKSTATSVTPIPSSTLGTTGT 4809 Query: 1124 SVPKLTSPVTSISPIQAS---EKTAVSDIL--KMSLMEAQIDTNVEH------MIVDPPK 1172 + T+PV ++S I S E T S +L K + A T+ I+ Sbjct: 4810 LPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELT 4869 Query: 1173 KALATSMLTGEA---GSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPP 1229 A T+ TG S P T ++ + + + + ST G TT + P Sbjct: 4870 TAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG---TTWILTEP 4926 Query: 1230 AVPAT 1234 + AT Sbjct: 4927 STTAT 4931 >gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] Length = 1486 Score = 80.1 bits (196), Expect = 1e-14 Identities = 224/1122 (19%), Positives = 394/1122 (35%), Gaps = 201/1122 (17%) Query: 226 PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSP 285 P I+ + SP SN ++ P K+ T P+ + TT+ V Sbjct: 82 PHDTLISETLLNSPVSSN-----TSTTPTSKFAFKVETTPPTVLVYSATTECVY------ 130 Query: 286 SSTFVPNILSKSHNYAAVTKLVPTSVIAST--TQKPPVVITASQSSLVSNSSSGSSSSTP 343 ++F+ I + T++ TS ST TQKP +T++ S ++ + G+S+ T Sbjct: 131 PTSFIITISHPTSICVTTTQVAFTSSYTSTPVTQKPVTTVTSTYS--MTTTEKGTSAMTS 188 Query: 344 SPIPNTVAVTAVVSSTPSVVMSTVAQGVST-SAIKMASTRLPSPKSLVSAPTQILAQFPK 402 SP T T +V+ TPS V +T +T S+ + R P P + T Sbjct: 189 SPSTTTARETPIVTVTPSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTT-------- 240 Query: 403 QHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQ 462 SP P + T++ S I + Sbjct: 241 -----------------------------------SPTP--VFTTLKTAVTSTSPITSSI 263 Query: 463 VQPSKILPKPVTATLPTSSN---SPIMVVSSNGAIMTTKLV------TTPTGTQATYTRP 513 + + TA+ PT++N SP + S+ +++T+ + TTP T T Sbjct: 264 TSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPVLSTETITSGITNTTPLSTLVTTLPT 323 Query: 514 TVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMT 573 T+S S TP + T T+ S +T KI S ++GT + T++P T Sbjct: 324 TISRS------TPTSETTYPTSPTSTVT-------DSTTKIAYSTSMTGTLSTETSLPPT 370 Query: 574 SKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRP-ITK 632 S TT TT P N+VTT T + + + + P T Sbjct: 371 SSS-----LPTTETATT----PMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTS 421 Query: 633 MIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETL 692 I T ST + + TK + LI T +T S + TET Sbjct: 422 SITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHST-PSFTSSITTTETT 480 Query: 693 QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEI 752 ++R + ++ + +++T SS ++TE+ + H Sbjct: 481 SHSARSFTSSITTTETTSHNTRSFT-SSITTTET---------------------NSHST 518 Query: 753 AMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMT 812 TS + S + S +S+I TT + L S P + +T Sbjct: 519 TSFTSSITTTETTSHSTPSFSSSI--------TTTETPLHSTP----------GLTSWVT 560 Query: 813 QEKRHSPESPSIAVVESELVAEYITTERTDEGTE-VAFPLLVSHRSQPQQPSQPQRTLLQ 871 K S +P L + TTE T T + + + PS T+ Sbjct: 561 TTKTTSHITPG-------LTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYS 613 Query: 872 HVAQSQTA-----TQTSVVVKSIPASSPGAITHIMQQALSSHT---AFTKHSEELGTEEG 923 V+ S TA T + V P + T I +L + T T S T+ Sbjct: 614 TVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFP 673 Query: 924 EV-EEMDTLDPQTGLFYRSALTQS-QSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIH 981 + ++ TL +T + S QS +++ + P + ++ ++ + T Sbjct: 674 SIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSI 733 Query: 982 LQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQ 1041 + + + P + LT Q P P T + D TL P Sbjct: 734 VVIPETPTQTPPV---------LTSATGTQTSPAP----TTVTFGSTDSSTSTLHTLTPS 780 Query: 1042 TVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGS 1101 T + + +T Q+P + + + P TP Q SL ++SE T S T Sbjct: 781 TALSTIV--STSQVP--IPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAI 836 Query: 1102 SVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDT 1161 + T PT+ + SS SI+P+ + T + + + + + Sbjct: 837 LTSFSTIIWSSTPTIIMSSSPSS--------ASITPVFS---TTIHSVPSSPYIFSTENV 885 Query: 1162 NVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMAN-STPQQQKCRESCSSPSTVGSS 1220 + P + AT+ + + SL + + + S P C P T+ + Sbjct: 886 GSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLPSTTPC------PGTITIT 939 Query: 1221 LTTRKIDPPAVPATGQFMRIQNVGQKKAEESP-AEIIIQAIPQYAIPCHSSSNVVVEPSG 1279 + VPA+ ++ +A P + + + C +S ++ + Sbjct: 940 I---------VPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTT 990 Query: 1280 LLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAER 1321 ++ TS + + E+++ + SST GT P+ + ++ R Sbjct: 991 YMD----TSSMMPESESSISPNASSSTGTGTVPTNTVFTSTR 1028 Score = 75.5 bits (184), Expect = 3e-13 Identities = 165/839 (19%), Positives = 290/839 (34%), Gaps = 148/839 (17%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206 T+ TST + T G+ A SP + +V TV SVS +D Sbjct: 168 TTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIV-----TVTPSSVSATDTTFHTTISST 222 Query: 207 TNSSSSSPVVLKEVPKAVVP--------VSKTITVPVSGSPKMSNIMQSIANSLPPH--- 255 T ++ +P+ + P + T T P++ S +N + S+ + Sbjct: 223 TRTTERTPLPTGSIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTAT 282 Query: 256 ---MSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFV---PNILSKSHNYAAVT-KLVP 308 SP + + +T T T I T+P ST V P +S+S + T P Sbjct: 283 NTLSSPTRTILSSTPVLSTETITSG--ITNTTPLSTLVTTLPTTISRSTPTSETTYPTSP 340 Query: 309 TSVIASTTQKPPVVITASQSSLVSNSSS--GSSSSTP------SPIPNTVAVTAVVS--S 358 TS + +T K + + S + +S +S +SSS P +P+ N V T +S S Sbjct: 341 TSTVTDSTTK--IAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHS 398 Query: 359 TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418 TPS ST+ V++ + ++ + + ++ + + + F S + + Sbjct: 399 TPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLIT 458 Query: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478 T + + +P S + ++ +T T Sbjct: 459 TTETTSHSTP----------------------SFTSSITTTETTSHSARSFTSSITTTET 496 Query: 479 TSSN----SPIMVVSSNGAIMTTKLVTTPTGTQAT-YTRPTVSPSIGR----MAATPGAA 529 TS N + + + + TT ++ T T+ T ++ P+ S SI + +TPG Sbjct: 497 TSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLT 556 Query: 530 TYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGT 589 ++V TT +S+I G T+ ITT TS T T Sbjct: 557 SWVTTTK------------------TTSHITPGLTSSITTTETTSHSTPGFTSSITTTET 598 Query: 590 TIQGLPGKNVVTTLLNAGGEKTIQT----------VPTGAKPAILTATRPITKMIVTQPK 639 T + P + T T T PT P+ L+ P T + P Sbjct: 599 TSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPS 658 Query: 640 GIGS----TVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQA 695 +G+ T IPT I + + + ++ ++ S +T LV T Sbjct: 659 SVGTSTSLTTTTDFPSIPTDI-------STLPTRTHIISSSPSIQSTETSSLVGTTSPTM 711 Query: 696 SRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAME 755 S V + TE++ S S +V + E + Sbjct: 712 STVR-------------------MTLRITENTPISSFSTSIVVI----------PETPTQ 742 Query: 756 TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEK 815 T P + + S + T+ + +T+ S + SQ+ +P + Sbjct: 743 TPPVLTSATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTL 802 Query: 816 RHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQ 875 + +P +PS+ S TTE G+ +L S S S P + + Sbjct: 803 QTTPSTPSLQT--SLTSTSEFTTESFTRGSTSTNAILTSF-STIIWSSTPTIIMSSSPSS 859 Query: 876 SQTATQTSVVVKSIPAS---------SPGAITHIMQQALSSHTAFTKHSEELGTEEGEV 925 + S + S+P+S +IT + S+ T+ + S L T E+ Sbjct: 860 ASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEI 918 Score = 73.6 bits (179), Expect = 1e-12 Identities = 191/871 (21%), Positives = 316/871 (36%), Gaps = 135/871 (15%) Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK 167 P FT AV + + P+ + S V S T+T S PT+T S T+ Sbjct: 242 PTPVFTTLKTAVTSTS-------PITSSITSTNTVT-SMTTTASQPTATNTLSSPTRTIL 293 Query: 168 SPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPV 227 S P + + +T V+ T S S+P P + Sbjct: 294 SSTPVLSTETITSGITNTTPLSTLVTTLP----------TTISRSTPTSETTYPTSPTST 343 Query: 228 SKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSS 287 T ++ S M+ + S SLPP S + P+T+T T ++ TT SS Sbjct: 344 VTDSTTKIAYSTSMTGTL-STETSLPPTSSSL------PTTETATTPMTNLVTTTTEISS 396 Query: 288 TFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIP 347 P+ S + + P + TT + P T +S +N+ + +S +PS Sbjct: 397 HSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKT-TSHRSPSFTS 455 Query: 348 NTVAVTAVVSSTPSVVMS-TVAQGVS------TSAIKMASTRLPSPKSLVSAPTQILAQF 400 STPS S T + S TS+I T + +S S+ T + Sbjct: 456 LITTTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSIT--TTET 513 Query: 401 PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGI-------KPTIQIKQE 453 S + + + + S ++ + P S PG+ K T I Sbjct: 514 NSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHS--TPGLTSWVTTTKTTSHITPG 571 Query: 454 SGVKIITQQVQPSKI--LPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYT 511 I T + +T T TS ++P + SS+ T TT + T + Sbjct: 572 LTSSITTTETTSHSTPGFTSSITTTETTSESTPSL--SSSTIYSTVSTSTTAITSHFTTS 629 Query: 512 RPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTI 570 V+P+ TP + +T + TT S+ T+ P S+ T +++ S T I+T+ Sbjct: 630 ETAVTPT----PVTPSSLSTDIPTT--SLRTLTPSSVGTSTSLTTTTDFPS-IPTDISTL 682 Query: 571 P-----MTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILT 625 P ++S P++ + ++ GTT P + V L I + T ++ Sbjct: 683 PTRTHIISSSPSIQSTETSSLVGTT---SPTMSTVRMTLRITENTPISSFSTSI--VVIP 737 Query: 626 ATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQ-QGKTQVLIKPKPVTFQATVVSEQT 684 T T ++T G+ PA PT + +G T L P T +T+VS T Sbjct: 738 ETPTQTPPVLT--SATGTQTSPA----PTTVTFGSTDSSTSTLHTLTPSTALSTIVS--T 789 Query: 685 RQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSS----SSST---------------- 724 Q+ + ++ S+Q +T S S+ST Sbjct: 790 SQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTP 849 Query: 725 ----ESSQSSQDSQPV----VHVIASRRQDWSEHEI---AMETSPTIIYQDVSSESQSAT 773 SS SS PV +H + S +S + ++ P++ +S S +++ Sbjct: 850 TIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSS 909 Query: 774 STIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVA 833 S AL E+ + + P TI ++ + P SP+ VE + Sbjct: 910 SLTTALTEITPFSYISLPSTTPCPGTITITIV-------------PASPTDPCVEMD--- 953 Query: 834 EYITTERTDEGTE--VAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPA 891 +TE T T FP + P S Q TL ++ S S++ +S + Sbjct: 954 --PSTEATSPPTTPLTVFPFTTEMVTCPTSIS-IQTTLTTYMDTS------SMMPESESS 1004 Query: 892 SSPGAITHIMQQALSSHTAFTKHSEELGTEE 922 SP A + + ++T FT S L T E Sbjct: 1005 ISPNASSSTGTGTVPTNTVFT--STRLPTSE 1033 Score = 70.5 bits (171), Expect = 1e-11 Identities = 146/756 (19%), Positives = 272/756 (35%), Gaps = 83/756 (10%) Query: 110 TAFTVTANAVANAAIQHNA----SLPVPAETGSKEVVCY--SYTSTTSTPTSTPVPSGSI 163 +A + T++ HN S ET S + S T+T +T STP S SI Sbjct: 483 SARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSI 542 Query: 164 ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223 T ++P ++P V + +T ++ S T +SS + ++ Sbjct: 543 TTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTSES 602 Query: 224 VVPVSKTI---TVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVII 280 +S + TV S + S+ S P ++P ++ P+T T V Sbjct: 603 TPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGT 662 Query: 281 VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340 T+ ++T P+I + T ++ +S +T+ +V T S + + + Sbjct: 663 STSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITE 722 Query: 341 STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQF 400 +TP +T V + T + + T A G TS P+P ++ T + Sbjct: 723 NTPISSFSTSIVVIPETPTQTPPVLTSATGTQTS---------PAPTTVTFGSTD--SST 771 Query: 401 PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIIT 460 H +P L + +Q P P +H Q +P P ++ ++ E + T Sbjct: 772 STLHTLTPSTALSTIVSTSQ----VPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFT 827 Query: 461 QQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT----PTGTQATYTRPTVS 516 + + + + + +S+ + IM S + A +T TT P+ T S Sbjct: 828 RGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGS 887 Query: 517 PSI-GRMAATPGAATYVKTTSGSIIT----VVPKSLATL------GGKII---------- 555 SI G + + A T +TS S+ T + P S +L G I Sbjct: 888 ASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTD 947 Query: 556 -------SSNIVSGTTTKITTIPMTSK----PNVIVVQKTTGKGTTIQGLPGKNVVTTLL 604 S+ S TT +T P T++ P I +Q T + ++ + Sbjct: 948 PCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSSMMPESESSISP 1007 Query: 605 NAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKT 664 NA TVPT + T+TR T T + +IP + G + Sbjct: 1008 NASSSTGTGTVPTN---TVFTSTRLPT----------SETWLSNSSVIPLPL----PGVS 1050 Query: 665 QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724 + + KP + T++ +T T +R +E ++ Q P T ++ Sbjct: 1051 TIPLTMKPSSSLPTIL--RTSSKSTHPSPPTTRTSETPVATTQ----TPTTLTSRRTTRI 1104 Query: 725 ESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ 784 S ++Q + W + + A + + + Q+ + Sbjct: 1105 TSQMTTQSTLTTTAGTCDNGGTWEQGQCACLPGFSGDRCQLQTRCQNGGQWDGLKCQCPS 1164 Query: 785 TTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPE 820 T E Q +D+ + V ++++ +++ SP+ Sbjct: 1165 TFYGSSCEFAVEQVDLDVVETEVGMEVSVDQQFSPD 1200 >gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 79.7 bits (195), Expect = 2e-14 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 78.6 bits (192), Expect = 4e-14 Identities = 206/1094 (18%), Positives = 367/1094 (33%), Gaps = 104/1094 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPII---TQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVT 1133 + A SE TAS T GS T + G + T +S P T Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET 1243 Query: 1134 SISPIQASEKTAVS 1147 + + I SE T S Sbjct: 1244 NTAFIIGSETTIAS 1257 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 718 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 777 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 892 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011 Query: 927 EMDTL 931 E T+ Sbjct: 1012 ETTTV 1016 Score = 60.8 bits (146), Expect = 8e-09 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 51.2 bits (121), Expect = 6e-06 Identities = 122/629 (19%), Positives = 221/629 (35%), Gaps = 58/629 (9%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + + S T + K S + T + S + + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT---- 1148 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502 + + + V I + S T T ++ S S+ G+ TT + Sbjct: 1149 ------TVSETTTVSTIGSEATTSSAAGSEATTT--STEGSETTTASTAGSETTT---AS 1197 Query: 503 PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562 G++ T + + S A+T G+ T T+GS T P S G + ++ I+ Sbjct: 1198 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1251 Query: 563 TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617 TT +T + + +TT T G + T +L + +IQ + T Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311 Query: 618 GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677 T TR VT G+ T A+ +P IV G + T Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1370 Query: 678 TV--VSEQTRQLVTETLQQASRVAEAGNS 704 V + TR+ + T Q+ V+ N+ Sbjct: 1371 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1399 Score = 42.7 bits (99), Expect = 0.002 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + T + S+T+T ++ ++ AS+ G+ T S Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393 Query: 909 TAFTKHSEELGT 920 T + E T Sbjct: 394 TTVSTTGSETTT 405 >gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 79.7 bits (195), Expect = 2e-14 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 79.3 bits (194), Expect = 2e-14 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136 + A SE TAS T GS T + G + T +S P T+ + Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236 Query: 1137 PIQASEKTAVS 1147 I SE T S Sbjct: 1237 FIIGSETTIAS 1247 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 718 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 777 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 892 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011 Query: 927 EMDTL 931 E T+ Sbjct: 1012 ETTTV 1016 Score = 60.8 bits (146), Expect = 8e-09 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 50.4 bits (119), Expect = 1e-05 Identities = 111/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437 + + S T + K S + T + S + + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497 + I +G + T + S+ T T T+ + ++ T Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1206 Query: 498 KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557 + T T T T +PS +TT S ++ P + + G + + Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266 Query: 558 NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616 +I SG T TT+ T+ ++ + T I P TT ++ P Sbjct: 1267 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1323 Query: 617 TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676 +A IV G+G++ A+ T +G + T +P TFQ Sbjct: 1324 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1378 Query: 677 AT 678 T Sbjct: 1379 ET 1380 Score = 42.7 bits (99), Expect = 0.002 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + T + S+T+T ++ ++ AS+ G+ T S Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393 Query: 909 TAFTKHSEELGT 920 T + E T Sbjct: 394 TTVSTTGSETTT 405 >gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 79.7 bits (195), Expect = 2e-14 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 79.7 bits (195), Expect = 2e-14 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136 + A SE TAS T GS T + G + T +S P T+ + Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236 Query: 1137 PIQASEKTAVS 1147 I SE T S Sbjct: 1237 FIIGSESTIAS 1247 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 718 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 777 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 892 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011 Query: 927 EMDTL 931 E T+ Sbjct: 1012 ETTTV 1016 Score = 60.8 bits (146), Expect = 8e-09 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 48.9 bits (115), Expect = 3e-05 Identities = 110/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437 + + S T + K S + T + S + + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497 + I +G + T + S+ T T T+ + ++ T Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1206 Query: 498 KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557 + T T T T +PS ++T S ++ P + + G + + Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTV 1266 Query: 558 NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616 +I SG T TT+ T+ ++ + T I P TT ++ P Sbjct: 1267 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1323 Query: 617 TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676 +A IV G+G++ A+ T +G + T +P TFQ Sbjct: 1324 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1378 Query: 677 AT 678 T Sbjct: 1379 ET 1380 Score = 42.7 bits (99), Expect = 0.002 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + T + S+T+T ++ ++ AS+ G+ T S Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393 Query: 909 TAFTKHSEELGT 920 T + E T Sbjct: 394 TTVSTTGSETTT 405 >gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 79.7 bits (195), Expect = 2e-14 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 79.3 bits (194), Expect = 2e-14 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136 + A SE TAS T GS T + G + T +S P T+ + Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236 Query: 1137 PIQASEKTAVS 1147 I SE T S Sbjct: 1237 FIIGSETTIAS 1247 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 718 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 777 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 892 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011 Query: 927 EMDTL 931 E T+ Sbjct: 1012 ETTTV 1016 Score = 60.8 bits (146), Expect = 8e-09 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 53.5 bits (127), Expect = 1e-06 Identities = 121/629 (19%), Positives = 220/629 (34%), Gaps = 68/629 (10%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + + S T + K S + T + S + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM--------- 1143 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502 + T + + + AT +++ S S+ G+ TT + Sbjct: 1144 -------------TTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTT---AS 1187 Query: 503 PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562 G++ T + + S A+T G+ T T+GS T P S G + ++ I+ Sbjct: 1188 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1241 Query: 563 TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617 TT +T + + +TT T G + T +L + +IQ + T Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1301 Query: 618 GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677 T TRP VT G+ T A+ +P IV G + T Sbjct: 1302 PMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1360 Query: 678 TV--VSEQTRQLVTETLQQASRVAEAGNS 704 V + TR+ + T Q+ V+ N+ Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1389 Score = 42.7 bits (99), Expect = 0.002 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + T + S+T+T ++ ++ AS+ G+ T S Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393 Query: 909 TAFTKHSEELGT 920 T + E T Sbjct: 394 TTVSTTGSETTT 405 >gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] Length = 1704 Score = 79.7 bits (195), Expect = 2e-14 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 79.3 bits (194), Expect = 2e-14 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136 + A SE TAS T GS T + G + T +S P T+ + Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236 Query: 1137 PIQASEKTAVS 1147 I SE T S Sbjct: 1237 FIIGSETTIAS 1247 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 718 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 777 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 892 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011 Query: 927 EMDTL 931 E T+ Sbjct: 1012 ETTTV 1016 Score = 60.8 bits (146), Expect = 8e-09 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 53.5 bits (127), Expect = 1e-06 Identities = 121/629 (19%), Positives = 220/629 (34%), Gaps = 68/629 (10%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + + S T + K S + T + S + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM--------- 1143 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502 + T + + + AT +++ S S+ G+ TT + Sbjct: 1144 -------------TTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTT---AS 1187 Query: 503 PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562 G++ T + + S A+T G+ T T+GS T P S G + ++ I+ Sbjct: 1188 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1241 Query: 563 TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617 TT +T + + +TT T G + T +L + +IQ + T Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1301 Query: 618 GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677 T TRP VT G+ T A+ +P IV G + T Sbjct: 1302 PMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1360 Query: 678 TV--VSEQTRQLVTETLQQASRVAEAGNS 704 V + TR+ + T Q+ V+ N+ Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1389 Score = 42.7 bits (99), Expect = 0.002 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + T + S+T+T ++ ++ AS+ G+ T S Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393 Query: 909 TAFTKHSEELGT 920 T + E T Sbjct: 394 TTVSTTGSETTT 405 >gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 79.7 bits (195), Expect = 2e-14 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 78.6 bits (192), Expect = 4e-14 Identities = 206/1094 (18%), Positives = 367/1094 (33%), Gaps = 104/1094 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPII---TQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVT 1133 + A SE TAS T GS T + G + T +S P T Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET 1243 Query: 1134 SISPIQASEKTAVS 1147 + + I SE T S Sbjct: 1244 NTAFIIGSETTIAS 1257 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 718 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 777 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 892 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011 Query: 927 EMDTL 931 E T+ Sbjct: 1012 ETTTV 1016 Score = 60.8 bits (146), Expect = 8e-09 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 51.2 bits (121), Expect = 6e-06 Identities = 122/629 (19%), Positives = 221/629 (35%), Gaps = 58/629 (9%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + + S T + K S + T + S + + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT---- 1148 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502 + + + V I + S T T ++ S S+ G+ TT + Sbjct: 1149 ------TVSETTTVSTIGSEATTSSAAGSEATTT--STEGSETTTASTAGSETTT---AS 1197 Query: 503 PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562 G++ T + + S A+T G+ T T+GS T P S G + ++ I+ Sbjct: 1198 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1251 Query: 563 TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617 TT +T + + +TT T G + T +L + +IQ + T Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311 Query: 618 GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677 T TR VT G+ T A+ +P IV G + T Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1370 Query: 678 TV--VSEQTRQLVTETLQQASRVAEAGNS 704 V + TR+ + T Q+ V+ N+ Sbjct: 1371 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1399 Score = 42.7 bits (99), Expect = 0.002 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + T + S+T+T ++ ++ AS+ G+ T S Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393 Query: 909 TAFTKHSEELGT 920 T + E T Sbjct: 394 TTVSTTGSETTT 405 >gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 79.7 bits (195), Expect = 2e-14 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 78.6 bits (192), Expect = 4e-14 Identities = 206/1094 (18%), Positives = 367/1094 (33%), Gaps = 104/1094 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPII---TQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVT 1133 + A SE TAS T GS T + G + T +S P T Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET 1243 Query: 1134 SISPIQASEKTAVS 1147 + + I SE T S Sbjct: 1244 NTAFIIGSETTIAS 1257 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 718 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 777 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 892 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011 Query: 927 EMDTL 931 E T+ Sbjct: 1012 ETTTV 1016 Score = 60.8 bits (146), Expect = 8e-09 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 51.2 bits (121), Expect = 6e-06 Identities = 122/629 (19%), Positives = 221/629 (35%), Gaps = 58/629 (9%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + + S T + K S + T + S + + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT---- 1148 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502 + + + V I + S T T ++ S S+ G+ TT + Sbjct: 1149 ------TVSETTTVSTIGSEATTSSAAGSEATTT--STEGSETTTASTAGSETTT---AS 1197 Query: 503 PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562 G++ T + + S A+T G+ T T+GS T P S G + ++ I+ Sbjct: 1198 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1251 Query: 563 TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617 TT +T + + +TT T G + T +L + +IQ + T Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311 Query: 618 GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677 T TR VT G+ T A+ +P IV G + T Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1370 Query: 678 TV--VSEQTRQLVTETLQQASRVAEAGNS 704 V + TR+ + T Q+ V+ N+ Sbjct: 1371 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1399 Score = 42.7 bits (99), Expect = 0.002 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + T + S+T+T ++ ++ AS+ G+ T S Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393 Query: 909 TAFTKHSEELGT 920 T + E T Sbjct: 394 TTVSTTGSETTT 405 >gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 79.7 bits (195), Expect = 2e-14 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 79.7 bits (195), Expect = 2e-14 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136 + A SE TAS T GS T + G + T +S P T+ + Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236 Query: 1137 PIQASEKTAVS 1147 I SE T S Sbjct: 1237 FIIGSESTIAS 1247 Score = 69.3 bits (168), Expect = 2e-11 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647 TI G TT+ G E T+ T +G +T + TK+ T + +T Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717 Query: 648 AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705 I T + G + T + T +T SE T T ET ++ +E +S Sbjct: 718 EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758 I G E T +S+ +E+++ S S + V + A ET S Sbjct: 777 IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 759 TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 810 QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866 + T E+ + + SE+ T +E T TE + S + Sbjct: 892 ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951 Query: 867 RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011 Query: 927 EMDTL 931 E T+ Sbjct: 1012 ETTTV 1016 Score = 60.8 bits (146), Expect = 8e-09 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 48.9 bits (115), Expect = 3e-05 Identities = 110/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437 + + S T + K S + T + S + + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497 + I +G + T + S+ T T T+ + ++ T Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1206 Query: 498 KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557 + T T T T +PS ++T S ++ P + + G + + Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTV 1266 Query: 558 NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616 +I SG T TT+ T+ ++ + T I P TT ++ P Sbjct: 1267 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1323 Query: 617 TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676 +A IV G+G++ A+ T +G + T +P TFQ Sbjct: 1324 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1378 Query: 677 AT 678 T Sbjct: 1379 ET 1380 Score = 42.7 bits (99), Expect = 0.002 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + T + S+T+T ++ ++ AS+ G+ T S Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393 Query: 909 TAFTKHSEELGT 920 T + E T Sbjct: 394 TTVSTTGSETTT 405 >gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo sapiens] Length = 1521 Score = 79.0 bits (193), Expect = 3e-14 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T TA++ AA + + GS+ V + + TT+ T + + Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272 Query: 169 PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219 AS +GS + S S+ P + + +SS V E Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332 Query: 220 VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277 +A S+T TV +GS + + S T + ++TT +T+ + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 278 VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329 V+T+ S T +I ++ AV+ V + AST + + S S Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452 Query: 330 LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 + S+ GS ++T + + S + +T + + I +T + S Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512 Query: 390 VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445 +A + ++ + + V+ + + S + + G + Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 446 PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504 T + SG T + + + T ++++S S+ G+ TT T+ Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632 Query: 505 GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554 T A+ T + + S M +T G+ + +T GS T V + ++T G Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692 Query: 555 ISSNIVSGTTTKITTIPM-----TSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 + +I TTK++T +++ + I TG TT G TT + G Sbjct: 693 TTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667 +T TG++ T T T T +GS A+ I TK+ T V Sbjct: 751 ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806 Query: 668 IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725 + T +T SE T +ET+ ++ +E ++ EG E T+ S ++T Sbjct: 807 TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866 Query: 726 SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785 S++SS+ T+ T I + ++ S + T E +T Sbjct: 867 STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T S+ + S+ E + S S +E IT + EG+ Sbjct: 904 TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 E + T A S+T T ++ ++ AS G+ T + Sbjct: 962 ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 906 SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958 S T + E TE E + T +T Y + T ++ ++ +S Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018 E T L +T T + + I K T E ++ Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076 + A ++ T+ TV + V T A + ++ Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136 + A SE TAS T GS T + G + T +S P T+ + Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236 Query: 1137 PIQASEKTAVS 1147 I SE T S Sbjct: 1237 FIIGSETTIAS 1247 Score = 78.6 bits (192), Expect = 4e-14 Identities = 222/1125 (19%), Positives = 385/1125 (34%), Gaps = 107/1125 (9%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207 ST + T+TP P+GS T+ S SGS + S + S+ T Sbjct: 39 STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76 Query: 208 NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267 SS+ S T T ++GS + S ++ + + S Sbjct: 77 TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 TTN+TT VT++ S S A T T+ ++T + V TA Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181 Query: 328 SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382 S ++ S++GS ++T S TV+ T ++T S S T A + + K+++ Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442 + S + T + + + + T + + + S + Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Query: 443 GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500 I E+ K+ T + + + ++ S VS+ G+ TT + Sbjct: 302 ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360 Query: 501 ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556 +T + T + T + S A+T G+ AT V TT TV T Sbjct: 361 SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420 Query: 557 SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615 S + + +TT T +++ + I + T+ TT G TT+ AG E KT T Sbjct: 421 SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479 Query: 616 PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668 + A T T + ST V + T G + T Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539 Query: 669 KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711 + T + T VS + T++ + + A AG+ + Sbjct: 540 GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599 Query: 712 EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771 + +N T S++ S +S S+ S+ S + E + T+ + + + S + Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 772 ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828 + E +TT S+ T V I + T+ E+ + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEG 719 Query: 829 SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885 SE+ IT +E T TE + S ++ + + T + S T+++T++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777 Query: 886 --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938 ++ AS+ G+ T + A S T FT++SE T E + T +T Sbjct: 778 MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 S T + S + + + E ++ + + +T TI + + + S Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058 + T E ++ A T A + ++ V TT Sbjct: 898 TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955 Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118 A V ++ + A SE T S T GS T + EG + TV+ Sbjct: 956 VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008 Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178 ++ T T+I+ + SE T V+ S A T E T Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066 Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 TG + ST A + +T ++ ST GS TT Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105 Score = 67.8 bits (164), Expect = 7e-11 Identities = 188/906 (20%), Positives = 324/906 (35%), Gaps = 115/906 (12%) Query: 109 QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168 +T T + A ++ + TGS+ ++ S T TP++ + +++T S Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218 + ++ + ST + ++ + S + K T S++ S Sbjct: 203 -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261 Query: 219 EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264 E A SKT T +G P M++ M S +A+++ P + V + Sbjct: 262 ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321 Query: 265 KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 + +T +T + V+T+ S T +I+ + + T T+ AST Sbjct: 322 EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375 + S + S++GS ++T S + T S + V +TV + + S Sbjct: 380 GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439 Query: 376 ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 I +AST S +A T+ S + Y +T + S+ Sbjct: 440 GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491 + G T + S + S + T + S N+ + S Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 492 GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543 + TT L TT T T+ + T + + + +T G+ T +T+GS T V Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603 Query: 544 ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587 S +T G + +++ S TT + TT+ T +V TTG Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661 Query: 588 GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTV-Q 646 TI G TT+ G E T+ T +G +T + TK+ T G +T+ Sbjct: 662 ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTT---GSETTITS 716 Query: 647 PAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNS 704 I T + G + T + T +T SE T T ET ++ +E + Sbjct: 717 TEGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMA 775 Query: 705 SIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------S 757 SI G E T +S+ +E+++ S S + V + A ET S Sbjct: 776 SIM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS 830 Query: 758 PTIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP---- 808 TI SE+ + TS T A E +TT S+ T S+ Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEG 890 Query: 809 IQMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQP 865 + T E+ + + SE+ T +E T TE + S + Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950 Query: 866 QRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEV 925 T+ S+T T T++ ++ AS+ G+ T + A S T + E T Sbjct: 951 SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 926 EEMDTL 931 E T+ Sbjct: 1011 SETTTV 1016 Score = 62.8 bits (151), Expect = 2e-09 Identities = 165/923 (17%), Positives = 304/923 (32%), Gaps = 97/923 (10%) Query: 313 ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ASTT I S + S++GS ++TPSP T + T +VS + S + +T G Sbjct: 18 ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + + A + + S T A + T + Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 ++ + +G + T S+ T +++S S+ G Sbjct: 119 AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171 Query: 493 AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 + MTT T T T P+ + S +T G+ T +T+GS T + +T Sbjct: 172 SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222 Query: 553 KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612 + +++ + TTK++T + T G TT T T Sbjct: 223 ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276 Query: 613 QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672 T A T + P + + ST+ P TK+ T V Sbjct: 277 STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332 Query: 673 VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 +TV SE T T +E +SI G E + T S ++T S++ S+ Sbjct: 333 TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792 + + + SE T ++ + T T + + TTV E Sbjct: 384 T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435 Query: 793 SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848 + I ++ + + T E+ ++ SE Y TT ++ G E Sbjct: 436 ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 + + + T + T T + +++ T + L + Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T T+ SE E T D G S T + +A + + + T Sbjct: 555 TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027 +T T + + S + T + ++ ++ + + Sbjct: 609 ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080 + + T+ A +T V TT + K+ ++ I + + S+ Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASI 727 Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140 SE TAS T+GS T + EG + + + ++ TS T+++ I Sbjct: 728 -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200 SE T S I + + + + + + + +A++ + T V + + Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832 Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223 P E+ ++ ST GS TT Sbjct: 833 IPASTAGSETTTTTSTEGSETTT 855 Score = 50.4 bits (119), Expect = 1e-05 Identities = 111/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%) Query: 103 MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160 M + + + T A+ A+ + S +PA T E + TST + T+T Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859 Query: 161 GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217 GS T S + + + GS S S+ + T ++S+ + Sbjct: 860 GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 218 ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272 E A S+T T GS +++ + + + ++ + T T ++TT Sbjct: 917 STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975 Query: 273 TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322 +T + V+T+ S T +I + T T+V I ST Sbjct: 976 ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382 +T + S + ++GS ++T S + T VS+T S + + T+ + + + Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 383 LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437 + + S T + K S + T + S + + Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497 + I +G + T + S+ T T T+ + ++ T Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1206 Query: 498 KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557 + T T T T +PS +TT S ++ P + + G + + Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266 Query: 558 NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616 +I SG T TT+ T+ ++ + T I P TT ++ P Sbjct: 1267 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1323 Query: 617 TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676 +A IV G+G++ A+ T +G + T +P TFQ Sbjct: 1324 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1378 Query: 677 AT 678 T Sbjct: 1379 ET 1380 Score = 43.1 bits (100), Expect = 0.002 Identities = 158/835 (18%), Positives = 268/835 (32%), Gaps = 104/835 (12%) Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560 TT + T + T + S A+T G+ T + +GS T+V + Sbjct: 16 TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60 Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620 SG ++ITT N V + G GTT + G TT+ AG E T ++ TG + Sbjct: 61 SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113 Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680 +++A T T +TV A T + T T +T Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171 Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732 SE T +ET+ + + V+ AG+ + + T S++ S ++ S+ Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231 Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788 S+ A SE ++ S T SE+ +A + T A +TT Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286 Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848 S+P + + + T PE+ ++ SE+ + T + V Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340 Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 S+T T ++ ++ AS G+ T S Sbjct: 341 ---------------------------SETTTVSTTGSETTTASIMGSETSTDSTTGSET 373 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 T + E T E E T+ TG + T + S + + E +++ + Sbjct: 374 TTASTEGSETTTASTEGSEATTVS-TTG-----SETTTVSITDSETTTTCTEGSEMTAVS 427 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAK 1028 F+T T + + S + T + ++ K A Sbjct: 428 TTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS 487 Query: 1029 DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088 + L T T V + TT + + + T ++ S ++ T Sbjct: 488 NTGLET-------TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS--ENTTVST 538 Query: 1089 ASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVS- 1147 + T G T + EG + TV+ ++ T+ + SE T VS Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 1148 -DILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQK 1206 D + A +T A TS T A + S V+ + T Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658 Query: 1207 CRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIP 1266 + ST GS TT V ATG + G + I + Sbjct: 659 TGSERTITSTEGSETTT-------VSATGSETTVSTEG-----SGTTTVSITGSETTKVS 706 Query: 1267 CHSSSNVVVEPSGL-LELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAE 1320 S + G + + T + T + +STE S S + +E Sbjct: 707 TTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSE 761 >gi|167736355 mucin 4 isoform a [Homo sapiens] Length = 5284 Score = 78.2 bits (191), Expect = 5e-14 Identities = 278/1293 (21%), Positives = 449/1293 (34%), Gaps = 168/1293 (12%) Query: 113 TVTANAVANAAIQHNASLPVPAETG-SKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRP 171 T + + +A+ H A +P TG + +V ++ T S ++ P+G ++ SP Sbjct: 841 TQSTTELLSASASHGA---IPVSTGMASSIVPGTFHPTLSEASTAGRPTGQ-SSPTSPS- 895 Query: 172 ASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV--PVSK 229 ASP + T ++ SD + T++ S+ P + + P ++ Sbjct: 896 ASPQETAAISRMAQTQRTRTSRGSDTISLASQA--TDTFSTVPPTPPSITSTGLTSPQTE 953 Query: 230 TITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVI---------- 279 T T+ SGS K + +L + +P+ +T+ S T +TT V Sbjct: 954 THTLSPSGSGK------TFTTALISNATPLPVTYAS-SASTGHTTPLHVTDASSVSTGHA 1006 Query: 280 --IVTTSPSS------TFVPNILSKSHNYAAVTKLVPTSVI-ASTTQKPPVVITASQSS- 329 + TSPSS T +P + S + VT L TS AST P+ +T + S+ Sbjct: 1007 TPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSAS 1066 Query: 330 --------LVSNSSSGSSSSTPSPIPNTV-AVTAVVSSTPSVVMSTVAQGVSTSAIKMAS 380 + S SS+ + +TP P+ +T A T +S P S+V+ G T+ + + Sbjct: 1067 TGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTG-HTTPLPVTD 1125 Query: 381 TRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQP-SPVSHQQQPQQSP 439 T S S P + H +P T Q P + +S +P Sbjct: 1126 TSSASTGHATSLPVTDTSSVSTGHT-TPLHVTDASSASTGQATPLPVTSLSSVSTGDTTP 1184 Query: 440 LPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNS----PIMVVSSNGAI 494 LP + + + + T P PVT S++ P+ + S+ Sbjct: 1185 LPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG 1244 Query: 495 MTTKLVTTPTGT----QATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT---VVPKSL 547 TT L T T + QAT T + S+ TP T + S +T V S Sbjct: 1245 HTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSS 1304 Query: 548 ATLGGK--IISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT--- 602 A+ G + +++ S +T +P+TS + +TG T + +V T Sbjct: 1305 ASTGHATPLPVTSLSSASTGDTMPLPVTSPSSA-----STGDTTPLPVTDASSVSTGHTT 1359 Query: 603 ---LLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYG 659 + +A T Q P +T T + VT P ++ A ++ T Sbjct: 1360 PLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSS--ASTGHATPLLVTDTSSA 1417 Query: 660 QQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDS 719 G P PVT ++V ++ L AS G P TD+ Sbjct: 1418 STGHAT----PLPVTDASSVSTDHATSLPVTIPSAAST-----------GHTTPLPVTDT 1462 Query: 720 SSSST----------ESSQSSQDSQPVVHVIASRRQDWSEHEIAME-TSPTIIYQDVSSE 768 SS+ST SS S+ D+ P+ + S + H + TSP S Sbjct: 1463 SSASTGQATSLLVTDTSSVSTGDTTPLP--VTSTSSASTGHVTPLHVTSP--------SS 1512 Query: 769 SQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSP--------E 820 + + +T + L + + + P+ + P+ +T S Sbjct: 1513 ASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVT 1572 Query: 821 SPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQ--HVAQSQT 878 SPS A T +G P+ + P S T L + + T Sbjct: 1573 SPSSASTGHTTPLPVTDTSSASKGDTTPLPV-----TSPSSASTGHTTPLPVTDTSSAST 1627 Query: 879 ATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEEL---GTEEGEVEEMDTLDPQT 935 T + V + + S G T + S +A T H+ L T L P T Sbjct: 1628 GDTTPLPVTNASSLSTGHATPL--HVTSPSSASTGHATPLPVTSTSSASTGHATPL-PVT 1684 Query: 936 GLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMP 995 GL + ++ S + T L V +L T LP Sbjct: 1685 GLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTP-----------LPVTS 1733 Query: 996 QLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQP-PQTVVQVLAVKTTQQ 1054 S +PL A Q T P V + T A P P T + + T + Sbjct: 1734 PSSASTGHASPLLVTDASSASTGQATPLP-VTDTSSVSTAHATPLPVTGLSSASTDDTTR 1792 Query: 1055 LPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPI-ITQGSSVTKITFEGRQP 1113 LP V + + LP +S ++ P+ +T SS + T + Sbjct: 1793 LPVTD---------VSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSAS--TGDTTSL 1841 Query: 1114 PTVTKITGGSSVPKLTSPVTSISPIQASEKTA--VSDILKMSLMEAQ----IDTNVEHMI 1167 P VT + SS + PVT S + T+ V+D +S + DTN Sbjct: 1842 P-VTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTG 1900 Query: 1168 VDPPKKAL-ATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKI 1226 P A+S+ TG A SLP T + A ++TP S SS T +T Sbjct: 1901 DTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASS 1960 Query: 1227 DPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYA--IPCHSSSNVVVEPSGLLELN 1284 P + +V A P +A +P +S+V + L + Sbjct: 1961 VPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVT 2020 Query: 1285 NFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQS 1317 + +S D D S++ P P S Sbjct: 2021 SLSSASTGDTTPLPVTDTSSASTGQDTPLPVTS 2053 Score = 75.9 bits (185), Expect = 2e-13 Identities = 262/1263 (20%), Positives = 426/1263 (33%), Gaps = 171/1263 (13%) Query: 113 TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK----- 167 T T++A A + + P A TG + + TS+ ST +TP+P S+++V Sbjct: 2916 TDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTT 2975 Query: 168 ---------------SPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSS 212 +P P + S+ + + + S S D P T+S+S+ Sbjct: 2976 PLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSAST 3035 Query: 213 SPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTN 272 + P V +S T + P S S ++ P ++ T +T Sbjct: 3036 G----QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPV 3091 Query: 273 TTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVS 332 T+ V T+P P+ S H A + V + AST + +T + S+ Sbjct: 3092 TSLSSVSTGDTTPLPVTSPSSASTGH---ATSLPVTDTSSASTGDTTSLPVTDTSSAYTG 3148 Query: 333 NSSS-----GSSSSTPSPIPNTVAVTAVVS---STPSVVMSTVAQGVST---SAIKMAST 381 +++S SSSST P V T+ VS +TP +V T A ST + + + S Sbjct: 3149 DTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLV--TDASSASTGHATPLHVTSP 3206 Query: 382 RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQP-SPVSHQQQPQQSPL 440 S P + H +P T P + +S Q +PL Sbjct: 3207 SSASTGDTTPVPVTDTSSVSTGH-ATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPL 3265 Query: 441 PPGIKPTIQIKQESGVKIIT-QQVQPSKILPKPVTATLPTSSN--SPIMVVSSNGAIM-- 495 P ++ + + + P PVT+T S+ +P+ V S++ A Sbjct: 3266 PVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGH 3325 Query: 496 TTKLVTTPT---GTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552 TT L T T T T P SPS +A+ G T + T +P S +T Sbjct: 3326 TTPLPVTDTSSASTGDTTPLPVTSPS----SASTGHTTPLHVT-------IPSSASTGDT 3374 Query: 553 KIIS-SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGL-PGKNVVTTLLNAGGEK 610 + + S +T T +P+T +V T T++ + G + +A Sbjct: 3375 STLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSAS 3434 Query: 611 TIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKP 670 T Q P +T T ++VT + + A + T G T L Sbjct: 3435 TGQATPLPVTSLSSVSTGDTTPLLVTDASSV--STGHATPLPVTDTSSASTGDTTRL--- 3489 Query: 671 KPVTFQATVVSEQTRQLVTETLQQASR-----VAEAGNSSIQEGKEEPQNYTDSSSSST- 724 PVT ++ + Q L +L S + SS+ G P TD+SS+ST Sbjct: 3490 -PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTG 3548 Query: 725 ---------ESSQSSQDSQPVVHVIASRRQDWSEHEIAME---------------TSPT- 759 SS S+ + P+ I S + + TSP+ Sbjct: 3549 DTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSS 3608 Query: 760 -----IIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMA------VP 808 + V+S S ++T LL ++V + P D S + +P Sbjct: 3609 ASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATP--LPVTDASSASTGDTTPLP 3666 Query: 809 IQMTQEKRHSPESP----SIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQ 864 + T +P S++ V + T+ + T A PL V + P S Sbjct: 3667 VTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPV---TIPSSVST 3723 Query: 865 PQRTLLQHVAQSQTAT--QTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEE 922 L + S +T T + V + ++S G T + SS A T+H+ L Sbjct: 3724 GDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSS--ASTRHATPLPV-- 3779 Query: 923 GEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQL----QVKTLQCFQTKQKQ 978 DT T R +T SA + P+ T L T Sbjct: 3780 -----TDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVS 3834 Query: 979 TIHLQADQLQHK----------LPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAK 1028 T H + + + LP S+ TPL T P+ + Sbjct: 3835 TGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSP 3894 Query: 1029 DRQLPTLMAQPPQTVVQVLAVKTTQQLP-----KLQQAPNQPKIYVQPQTPQ----SQMS 1079 P T + T LP L P P + S + Sbjct: 3895 SSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLP 3954 Query: 1080 LPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQ 1139 + +S T P+ +S++ ++ P VT + S+ PVTS+S + Sbjct: 3955 VTDASSASTGHATPLPL----TSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVS 4010 Query: 1140 ASEKTAVSDILKMSLMEAQID-------TNVEHMIVDPPKKALATSMLTGEAGSLPSTHM 1192 + T + + S ++V P +S TG+ LP T Sbjct: 4011 TGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDT 4070 Query: 1193 VVAGMANSTPQQQKCRESCSS------PSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQK 1246 A ++TP S S+ P T SS++T P AV + + + Sbjct: 4071 SSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDSPL 4130 Query: 1247 KAE 1249 K E Sbjct: 4131 KME 4133 Score = 73.2 bits (178), Expect = 2e-12 Identities = 275/1225 (22%), Positives = 423/1225 (34%), Gaps = 221/1225 (18%) Query: 113 TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS---- 168 T T++A A + P A TG + + TS+ ST +TP+P S+++ + Sbjct: 2196 TDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTT 2255 Query: 169 PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSS------------SSPVV 216 P P + AS+V + S S S D P +S+S SS Sbjct: 2256 PLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSAST 2315 Query: 217 LKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS-----------PVKIT--- 262 P V +S T + P S S ++ P H++ P+ +T Sbjct: 2316 GHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSS 2375 Query: 263 -----------FTKPSTQTTNTTTQKVIIVTTSPSS---TFVPNILSKSHNYAAVTKLVP 308 T S+ +T TT + T+S S+ T +P S + T+L Sbjct: 2376 SASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPV 2435 Query: 309 TSVI-ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVM--S 365 T+V AST P+ +T S SS+ + +TP P +T +V+ +TP +V S Sbjct: 2436 TNVSSASTGHATPLPVT-------STSSASTGDTTPLPGTDTSSVSTG-HTTPLLVTDAS 2487 Query: 366 TVAQGVST----SAIKMASTRLPSPKSLVSAP---TQILAQFPKQHQQSPKQQLYQVQQQ 418 +V+ G +T ++ AST +P + P T P + S + Sbjct: 2488 SVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASS-----LSTRHA 2542 Query: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPVTATL 477 T V PS S + LP + + + T P PVT T Sbjct: 2543 TSLHVTSPSSAS---TGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTY 2599 Query: 478 PTSSNS----PIMVVSSNGAIMTTKLVTTPTGTQAT-YTRP---TVSPSIGRMAATPGAA 529 S+ P+ SS TT L T T + +T + P T + S+ ATP Sbjct: 2600 SASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHV 2659 Query: 530 TYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGT 589 T + S T +P + A+ S +T T++P+T +V TG T Sbjct: 2660 TSPSSASTGHTTPLPVTDAS-----------SVSTGHATSLPVTDASSVF-----TGHAT 2703 Query: 590 TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAA 649 ++ VT +A T P A +T T + VT + + Sbjct: 2704 SLP-------VTIPSSASSG---HTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPL 2753 Query: 650 KIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL-VTETLQ----QASRVAEAGNS 704 + V P P+T ++V + T L VT+T QA+ + S Sbjct: 2754 PVTDASSVSTGHAT------PLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLS 2807 Query: 705 SIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQD 764 S+ G P TD+SS+ST S PV ++ + H + + T Sbjct: 2808 SVSTGDTTPLPVTDTSSAST----GHATSLPVTDTSSAS----TGHATPLPDTDT----- 2854 Query: 765 VSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQM----AVPIQMTQEKRHSPE 820 S+ ST A L T + P D S + A P+ +T SP Sbjct: 2855 ------SSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVT-----SPS 2903 Query: 821 SPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLL--QHVAQSQT 878 S S V T+ + T A PL H + P S T L + + T Sbjct: 2904 SASTGHATPLPV-----TDTSSASTGHANPL---HVTSPSSASTGHATPLPVTDTSSAST 2955 Query: 879 ATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLF 938 T + V S+ + S G T + S +A T H+ L DT TG Sbjct: 2956 GHATPLPVTSLSSVSTGDTTPL--PVTSPSSASTGHTTPLPV-------TDTSSASTGQA 3006 Query: 939 YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998 +T + SA + T L V T Q LP S Sbjct: 3007 TALPVTSTSSASTG-------DTTPLPVTDTSSASTGQAT-----------PLPVTSLSS 3048 Query: 999 IRHQKLTPLQQEQAQPKPDVQHTQH--PMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLP 1056 + TPL P T H P++ D + P V + +V T P Sbjct: 3049 VSTGDTTPL----PVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTP 3104 Query: 1057 KLQQAPNQ---------PKIYVQPQTPQSQMSLPA--SSEKQTASQVEQPIITQGSSVTK 1105 +P+ P + SLP +S T P+ SS T Sbjct: 3105 LPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTG 3164 Query: 1106 ITFEGRQPPTVTK---ITGGSSVPKLTSPVTSIS-----PIQASEKTAVS--DILKMSLM 1155 T P VT+ ++ G + P L + +S S P+ + ++ S D + + Sbjct: 3165 DT----TPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVT 3220 Query: 1156 EAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSS-- 1213 + ++V P +S TG+ LP T + A +TP S S+ Sbjct: 3221 DT---SSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGD 3277 Query: 1214 ----PSTVGSSLTTRKIDPPAVPAT 1234 P T SS +T P V +T Sbjct: 3278 TMPLPVTSPSSASTGHATPLPVTST 3302 Score = 71.6 bits (174), Expect = 5e-12 Identities = 265/1355 (19%), Positives = 456/1355 (33%), Gaps = 165/1355 (12%) Query: 47 DLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRL 106 ++ G +S+ S S E + + N +T+ ++ S+ + VP+ L Sbjct: 230 NVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSL 289 Query: 107 VPQTAFTVTA--------NAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPV 158 +P T+ + + + Q + +T S E S +T +T TPV Sbjct: 290 MPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNT--LTPV 347 Query: 159 PSGSIATVKSPRPASPASNVV--VLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVV 216 + ++ + SP +P+ V PSG T S S+ K R +S S Sbjct: 348 TTSTV--LSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDS--T 403 Query: 217 LKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA-------NSLPPHMSPVKITFTKPSTQ 269 L + + VS TI+ S K+S I S +SLPP +S T + Sbjct: 404 LGNTEETSLSVSGTISAITS---KVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAE 460 Query: 270 TTNTTTQKVI--------IVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPV 321 TT ++ I T ++T+ + SK H + T+L TS A+T Sbjct: 461 TTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRL---- 516 Query: 322 VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTA------VVSSTPSVVMSTVAQGVSTSA 375 + N S+G++ + P +P+ V+ SS + + T G T Sbjct: 517 --------VTGNPSTGTAGTIPR-VPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQW 567 Query: 376 IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQ-- 433 + T + ++L+S+P+ + Q K + + + T QQ+ +H Sbjct: 568 TQETGT---TGEALLSSPSYSVTQMIKTATSPSSSPM--LDRHTSQQITTAPSTNHSTIH 622 Query: 434 ----QPQQSPLPP--GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMV 487 PQ+SP G Q QES + +K + P ++ S +SP + Sbjct: 623 STSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTP-GSSFTASGHSPSEI 681 Query: 488 VSSNGAIMT--TKLVTTPTG----TQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541 V + ++ T PTG TQA T +PS P T + T +T Sbjct: 682 VPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGA--LT 739 Query: 542 VVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT 601 + ++T GG S +T+ T MT + T G T P + Sbjct: 740 LANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQA---ESTEASGQTQTSEPASSGSR 796 Query: 602 TLLNAGGEKTIQTVPTGAKPAILT--ATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYG 659 T +AG + +G P+ +T T + P T Q +++ +G Sbjct: 797 TT-SAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHG 855 Query: 660 Q-QGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTD 718 T + P TF T+ +EA + G+ P T Sbjct: 856 AIPVSTGMASSIVPGTFHPTL-------------------SEASTAGRPTGQSSP---TS 893 Query: 719 SSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKA 778 S+S E++ S+ +Q SR D I++ + T + V S TST Sbjct: 894 PSASPQETAAISRMAQ-TQRTRTSRGSD----TISLASQATDTFSTVPPTPPSITSTGLT 948 Query: 779 LLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYIT- 837 + + T+ K + + +P+ +P S + + T Sbjct: 949 SPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATP 1008 Query: 838 ---TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSP 894 T + T PL V+ S + + + + T T + V ++S Sbjct: 1009 LPVTSPSSVSTGHTTPLPVTDTSS-ESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSAST 1067 Query: 895 GAITHIMQQALSSHTA-------FTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQ 947 G +T + +LSS + T S + DT TG +T + Sbjct: 1068 GHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTS 1127 Query: 948 SAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPL 1007 SA + P+ T V T Q LP S+ TPL Sbjct: 1128 SASTGHATSLPVTDTS-SVSTGHTTPLHVTDASSASTGQAT-PLPVTSLSSVSTGDTTPL 1185 Query: 1008 QQEQAQPKPDVQHTQH--PMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQP 1065 P T H P++ D + P V +V T P+ Sbjct: 1186 PVTS----PSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAA 1241 Query: 1066 KIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSV------TKITFEGRQPPT-VTK 1118 P + S ++ + + + ++ G + T G P VT Sbjct: 1242 STGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTS 1301 Query: 1119 ITGGSSVPKLTSPVTSIS----------PIQASEKTAVSDILKMSLMEAQIDTNVEHMIV 1168 + S+ PVTS+S P+ + + D + + +A ++V Sbjct: 1302 PSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDA---SSVSTGHT 1358 Query: 1169 DPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSS-LTTRKID 1227 P A+S TG+A LP T + ++TP +SPS+ + T + Sbjct: 1359 TPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPL------PVTSPSSASTGHATPLLVT 1412 Query: 1228 PPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFT 1287 + +TG + A + IP A H++ L + + + Sbjct: 1413 DTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTP---------LPVTDTS 1463 Query: 1288 SQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS 1322 S + + D S + T P P S++ S Sbjct: 1464 SASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAS 1498 Score = 68.9 bits (167), Expect = 3e-11 Identities = 263/1232 (21%), Positives = 427/1232 (34%), Gaps = 165/1232 (13%) Query: 111 AFTVTANAVANAAIQHNASLPVP----AETGSKEVVCYSYTSTTSTPTSTPVPSGSIATV 166 A ++ ++ + H LPV TG + + TS+ ST +TP+P S+++ Sbjct: 1966 ATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSA 2025 Query: 167 K----SPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSS---SSPVVLKE 219 +P P + S+ S S D P +S+S ++P+++ + Sbjct: 2026 STGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTD 2085 Query: 220 VPKAVVPVSKTITVPVSGSPKMSN---IMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ 276 + ++ V + S + + + A+SL + T PS+ +T TT Sbjct: 2086 ASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTG-DTTPLPVTSPSSASTGDTTP 2144 Query: 277 KVIIVTTSPS-----STFVPNILSKSHNYAAVTKLVPTSVI---------------ASTT 316 + T+S S S V + S S +A + TS AST Sbjct: 2145 LPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTG 2204 Query: 317 QKPPVVITASQSS--------LVSNSSSGSS-SSTPSPIPN-TVAVTAVVSSTPSVVMST 366 Q P+ +T+ S+ LV+++SS S+ +TP P+ + + A T + P S+ Sbjct: 2205 QATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASS 2264 Query: 367 VAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQ-VAQ 425 V+ G +TS + T L S + + P + + P L+ + A Sbjct: 2265 VSTGHATS---LPVTSLSSVSTGDTTPLPVTS--PSSASTGHATPLHVTDASSASTGHAT 2319 Query: 426 PSPV---SHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSS 481 P PV S +PLP + + + + V P PVT++ SS Sbjct: 2320 PLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASS 2379 Query: 482 NS----PIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG 537 P+ SS TT L T T + +T T P G +A+ G T + T+ Sbjct: 2380 GHTTPLPVTDASSASTGDTTPLPVTDTSSAST-GHATHLPVTGLSSASTGDTTRLPVTNV 2438 Query: 538 SI--------ITVVPKSLATLGGKI-ISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKG 588 S + V S A+ G + S +T TT + + + + TT Sbjct: 2439 SSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLP 2498 Query: 589 TTIQGLPGKNVVTTL--LNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQ 646 T T L + T T P A +TR T + VT P + Sbjct: 2499 VTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHA 2558 Query: 647 PAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL-VTETLQ----QASRVAEA 701 + + T P PVT ++ + T L VT+T QA+ + Sbjct: 2559 TSLPVTDTSAASTGHA------TPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVT 2612 Query: 702 GNSSIQEGKEEPQNYTDSSSSST----------ESSQSSQDSQPVVHVIASRRQDWSEHE 751 SS G P TD+SS+ST SS S+ + P +HV + Sbjct: 2613 DTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATP-LHVTSPSSASTG--- 2668 Query: 752 IAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQM 811 T+P + S + ATS + + P+ S P+ + Sbjct: 2669 ---HTTPLPVTDASSVSTGHATSL--PVTDASSVFTGHATSLPVTIPSSASSGHTTPLPV 2723 Query: 812 TQEKRHSP-ESPSIAVVESELVA-----EYITTERTDEGTEVAFPL-LVSHRSQPQQPSQ 864 T S + S+ V ++ V+ T+ + T A PL L S S + Sbjct: 2724 TDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTT 2783 Query: 865 PQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGE 924 P + + + T T + V S+ + S G T + SS A T H+ L + Sbjct: 2784 P--LPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSS--ASTGHATSLPVTDTS 2839 Query: 925 ---------VEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTK 975 + + DT TG +T + SA T L V T Sbjct: 2840 SASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIG-------HATSLPVTDTSSISTG 2892 Query: 976 QKQTIHLQADQLQH-----KLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQH--PMVAK 1028 +H+ + LP S PL P T H P+ Sbjct: 2893 HATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLH----VTSPSSASTGHATPLPVT 2948 Query: 1029 DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088 D + P V + +V T P +P+ TP + + +S T Sbjct: 2949 DTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSAS--TGHTTP---LPVTDTSSAST 3003 Query: 1089 ASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSD 1148 P+ + S+ T T P VT + S+ PVTS+S + + T + Sbjct: 3004 GQATALPVTSTSSASTGDT----TPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLP- 3058 Query: 1149 ILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCR 1208 S A ++ D A+S TG+A LP T + ++TP Sbjct: 3059 --VTSPSSASTGHATPLLVTD------ASSASTGQATPLPVTSLSSVSTGDTTPLPVTSP 3110 Query: 1209 ESCSS------PSTVGSSLTTRKIDPPAVPAT 1234 S S+ P T SS +T D ++P T Sbjct: 3111 SSASTGHATSLPVTDTSSASTG--DTTSLPVT 3140 Score = 68.2 bits (165), Expect = 5e-11 Identities = 266/1261 (21%), Positives = 429/1261 (34%), Gaps = 207/1261 (16%) Query: 126 HNASLPVP----AETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS----PRPASPASN 177 H SLPV A +G + + S+ ST +T +P ++V + P P + AS+ Sbjct: 2701 HATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASS 2760 Query: 178 VVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVV-LKEVPKAVVPVSKTITVPVS 236 V + S S D P T+S+S+ L + V T +PV+ Sbjct: 2761 VSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVT 2820 Query: 237 GSPKMSNIMQSIANSLPP---------HMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSS 287 + S A SLP H +P+ P T T++ +T ++ + +S Sbjct: 2821 DTSSAST---GHATSLPVTDTSSASTGHATPL------PDTDTSSASTGHATLLPVTDTS 2871 Query: 288 TFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIP 347 S S +A + TS I ST P+ +T S SS+ + +TP P+ Sbjct: 2872 -------SASIGHATSLPVTDTSSI-STGHATPLHVT-------SPSSASTGHATPLPVT 2916 Query: 348 NTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQS 407 +T + + ++ V + A + + + T S P L+ Sbjct: 2917 DTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSV------- 2969 Query: 408 PKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPS 466 T V PS S +PLP + Q + + + T Sbjct: 2970 ------STGDTTPLPVTSPSSAS---TGHTTPLPVTDTSSASTGQATALPVTSTSSASTG 3020 Query: 467 KILPKPVTATLPTSSNS----PIMVVSSNGAIMTTKL-VTTPTGTQATYTRP---TVSPS 518 P PVT T S+ P+ +SS TT L VT+P+ + P T + S Sbjct: 3021 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASS 3080 Query: 519 IGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNV 578 ATP T + + S T +P + + ++++ T+ +T TS P Sbjct: 3081 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVT 3140 Query: 579 IVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKT------IQTVPTG-AKPAILT-----A 626 TG T++ V T ++ G+ T +V TG A P ++T + Sbjct: 3141 DTSSAYTGDTTSLP------VTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSAS 3194 Query: 627 TRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVT-FQATVVSEQTR 685 T T + VT P + + T V P PVT + + TR Sbjct: 3195 TGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHAT------PLPVTGLSSASTGDTTR 3248 Query: 686 QLVTE----TLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST----------ESSQSSQ 731 VT+ + QA+ + SS+ G P T SS+ST SS S+ Sbjct: 3249 LPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTG 3308 Query: 732 DSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKL 791 + PV + S + H T+P + D SS S T+ + +T Sbjct: 3309 HATPVP--VTSTSSASTGH-----TTPLPV-TDTSSASTGDTTPLPVTSPSSASTG---- 3356 Query: 792 ESKPRQPTI-------DLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEG 844 + P TI D S + V + H+ P T+ + Sbjct: 3357 HTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLP--------------VTDTSSVS 3402 Query: 845 TEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQA 904 T A PL V+ S + + + T T + V S+ + S G T ++ Sbjct: 3403 TGHATPLPVTSLSSVSTGDTTPLPVTD-ASSASTGQATPLPVTSLSSVSTGDTTPLLVTD 3461 Query: 905 LSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQL 964 SS + T H+ L DT TG R +T + SA + T L Sbjct: 3462 ASSVS--TGHATPLPVT-------DTSSASTGDTTRLPVTDTSSASTG-------QATPL 3505 Query: 965 QVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHP 1024 V +L T D + +S H P+ + D T+ P Sbjct: 3506 PVTSLSSVST---------GDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDT--TRLP 3554 Query: 1025 MVAKDRQLPTLMAQP-PQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPAS 1083 V T A P P T+ + T LP + + TP + + + Sbjct: 3555 -VTDTSSASTGQATPLPVTIPSSSSSGHTTPLP----VTSTSSVSTGHVTP---LHVTSP 3606 Query: 1084 SEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEK 1143 S T P+ + S+ T P VT + S+ PVT S + Sbjct: 3607 SSASTGHVTPLPVTSTSSASTGHA----TPLLVTDASSVSTGHATPLPVTDASSASTGDT 3662 Query: 1144 TA--VSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANST 1201 T V+D S +A P +S+ TG+ LP T A ++T Sbjct: 3663 TPLPVTDTSSASTGQAT-----------PLPVTSLSSVSTGDTTPLPVTDASSASTGHAT 3711 Query: 1202 PQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIP 1261 P S S+ T+ +T+ P+ +TG + G A Sbjct: 3712 PLPVTIPSSVSTGDTMPLPVTS-----PSSASTGHATPLPVTGLSSASTGDTT------- 3759 Query: 1262 QYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAER 1321 +P +S+ + L + + +S DD D+ S++ P P S++ Sbjct: 3760 --PLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSA 3817 Query: 1322 S 1322 S Sbjct: 3818 S 3818 Score = 63.2 bits (152), Expect = 2e-09 Identities = 136/554 (24%), Positives = 213/554 (38%), Gaps = 73/554 (13%) Query: 126 HNASLPVP----AETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK----SPRP---ASP 174 H LPV A TG + + TS+ ST +TP+P S+++V +P P AS Sbjct: 3645 HATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASS 3704 Query: 175 ASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVP 234 AS P T+ SVS D P +S SS P V +S T Sbjct: 3705 ASTGHATPLPVTI-PSSVSTGDTMPLP------VTSPSSASTGHATPLPVTGLSSASTGD 3757 Query: 235 VSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNIL 294 + P + +++ H +P+ +T T S+ +T+ TT+ + +S S+ + Sbjct: 3758 TTPLP-----VTDTSSASTRHATPLPVTDT--SSASTDDTTRLPVTDVSSASTGHATPLP 3810 Query: 295 SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL--VSNSSSGSSSSTPSPIPNTVAV 352 S + A+ P V +++ V T +SL S SS+ + +TP P+ +T +V Sbjct: 3811 VTSTSSASTGDTTPLPVTDTSS-----VSTGHATSLPVTSRSSASTGHATPLPVTDTSSV 3865 Query: 353 -TAVVSSTPSVVMSTVAQGVST----SAIKMASTRLPSP---KSLVSAPTQILAQFPKQH 404 T + P S+V+ G +T ++ AST +P S SA T P + Sbjct: 3866 STGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTN 3925 Query: 405 QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIIT-QQV 463 S T V PS S + S LP + + + + + V Sbjct: 3926 ASS-----LSTGHATPLHVTSPSSAS---RGDTSTLPVTDASSASTGHATPLPLTSLSSV 3977 Query: 464 QPSKILPKPVTATLPTSSNS----PIMVVSSNGAIMTTKL-VTTPTGTQATYTRP---TV 515 P PVT T S+ P+ +SS TT L VT P+ + +T T Sbjct: 3978 STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTD 4037 Query: 516 SPSIGRMAATPGAATYVKTTSGSIITVVP---KSLATLG--GKIISSNIVSGTTTKITTI 570 + S+ TP T + S T +P S A+ G + ++ S +T T + Sbjct: 4038 ASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPL 4097 Query: 571 PMTSKPNV-------IVVQKTTGKGTTIQGLPGK----NVVTTLLNAGGEKTIQTVPTGA 619 P+TS +V + V T T P K + T L G + T P Sbjct: 4098 PVTSLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPT 4157 Query: 620 KPAILTATRPITKM 633 + +T P T M Sbjct: 4158 TSQTIISTIPSTAM 4171 Score = 62.4 bits (150), Expect = 3e-09 Identities = 159/703 (22%), Positives = 263/703 (37%), Gaps = 122/703 (17%) Query: 110 TAFTVTANAVANAAIQHNASLPVP----AETGSKEVVCYSYTSTTSTPTSTPVPSGSIAT 165 T+ VT + A+ H LPV A TG + + TS+ ST +TP+P S ++ Sbjct: 1231 TSLPVTIPSAASTG--HTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSS 1288 Query: 166 ----------VKSPRPAS-------PASNVVVLPSGSTV---YVKSVSCSDEDEKPRKRR 205 V SP AS P +++ +G T+ S S D P Sbjct: 1289 ASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVT 1348 Query: 206 RTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265 +S S+ P V S T + P S S ++ P + T Sbjct: 1349 DASSVSTGHTT----PLHVTDASSASTGQATPLPVTSLSSVSTGDTTP-------LPVTS 1397 Query: 266 PSTQTTNTTTQKVIIVTTSPSSTF-----VPNILSKSHNYA-AVTKLVPTSVIASTTQKP 319 PS+ +T T ++ T+S S+ V + S S ++A ++ +P++ T Sbjct: 1398 PSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPL 1457 Query: 320 PVVITASQSS------LVSNSSSGSSS-STPSPIPNTVA-----VTAVVSSTPSVVMSTV 367 PV T+S S+ LV+++SS S+ +TP P+ +T + VT + ++PS + Sbjct: 1458 PVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGH 1517 Query: 368 AQGVSTSAIKMASTR------LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421 A + +++ AST + SP S + T L + V + Sbjct: 1518 ATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSA 1577 Query: 422 QVAQPSPV-----SHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPVT- 474 +P+ S + +PLP + + + + T P PVT Sbjct: 1578 STGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTN 1637 Query: 475 -ATLPTSSNSPIMVVSSNGA-------IMTTKLVTTPTG----------TQATYTRPTVS 516 ++L T +P+ V S + A + T + TG + AT T Sbjct: 1638 ASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRL 1697 Query: 517 PSIGRMAATPGAATYVKTTSGSIIT--------VVPKSLATLG--GKIISSNIVSGTTTK 566 P +A+ G AT + TS S ++ V S A+ G ++ ++ S +T + Sbjct: 1698 PVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQ 1757 Query: 567 ITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTA 626 T +P+T +V T LP VT L +A + T + T A Sbjct: 1758 ATPLPVTDTSSVSTAHATP--------LP----VTGLSSASTDDTTRLPVTDVSSASTGQ 1805 Query: 627 TRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQ 686 P+ VT P ++ + T G T L PVT ++ S T Sbjct: 1806 AIPLP---VTSPSS--ASTGDTTPLPVTDASSASTGDTTSL----PVTIPSSASSGHTTS 1856 Query: 687 L-VTETLQ----QASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724 L VT+ A+ + SS+ G P TD++S+ST Sbjct: 1857 LPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSAST 1899 Score = 60.5 bits (145), Expect = 1e-08 Identities = 264/1338 (19%), Positives = 450/1338 (33%), Gaps = 188/1338 (14%) Query: 56 LSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVT 115 +S S++ H+ + + + T+ M+ SS S+ +M P T Sbjct: 70 ISASSQNHQTKSTETTSKAQTDTLTQMMTSTLFSSP-SVHN-----VMETAPPDEMTTSF 123 Query: 116 ANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPA 175 ++V N + + ++ + T S + TST T +STPV S T + Sbjct: 124 PSSVTNTLMMTSKTITMTTSTDST-LGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTT 182 Query: 176 SNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPV 235 S ++ S S ++ R + T S +S T+T Sbjct: 183 S--------WRTSIQDTSASSQNHWTRSTQTTRESQTS----------------TLTHRT 218 Query: 236 SGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTT--TQKVIIVTTSPSSTFVPNI 293 + +P S + ++ ++ SP T T TNT+ T + I VTTS ST Sbjct: 219 TSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTL--GN 276 Query: 294 LSKSHNYAAVTKLVPTSVIASTTQKP--PVVITASQSSLVSNSSSGSSSSTPSPIPNTVA 351 ++ + L+P + A T P T S++S ++ + T S V+ Sbjct: 277 PGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVS 336 Query: 352 VTAVVSSTPSVVMSTVAQGVS--TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPK 409 +++ V STV S + ++ PS ++ S+P+ + F Sbjct: 337 QINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTF--------- 387 Query: 410 QQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKIL 469 + + ++ S + + ++ S T ++ ++ + PS + Sbjct: 388 ---LVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLP 444 Query: 470 PKPVTATLPTSSNSPIMVVSSNGAIMT----TKLVTTPTGTQATYT--RPTVSPSIGRMA 523 PK TA S GA T + +P +Q +T T PS Sbjct: 445 PKISTA---------FHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPS---SF 492 Query: 524 ATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTI-----PMTSKPNV 578 ++ G T+ +T S T L T ++ + +K++ I P T + Sbjct: 493 SSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHS 552 Query: 579 IVVQKTTGKGTTIQGLPGKNVV-TTLLNAGGEKTIQTVPTGAKPAIL-TATRPITKMIVT 636 + KTTG G Q LL++ Q + T P+ R ++ I T Sbjct: 553 TTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITT 612 Query: 637 QPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQAS 696 P ST+ + Q+G TQ Q T S+ TR + + Sbjct: 613 APSTNHSTIHSTSTSPQESPAVSQRGHTQAP--------QTTQESQTTRSV--SPMTDTK 662 Query: 697 RVAEAGNSSIQEGKEE----PQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEI 752 V G+S G PQ+ S+++T + + D + + S H+ Sbjct: 663 TVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDA 722 Query: 753 AMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMT 812 + S S S T + T+ + S P P Q T Sbjct: 723 TLGPS--------GGTSLSKTGAL---------TLANSVVSTPGGPE---GQWTSASAST 762 Query: 813 QEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQH 872 + + + +E + T+E G+ + S + P + + Sbjct: 763 SPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGS--EG 820 Query: 873 VAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKH-----------SEELGTE 921 ++ S T+ S S+P +H Q +A H S GT Sbjct: 821 ISTSGETTRFS--------SNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTF 872 Query: 922 EGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIH 981 + E T TG +S+ T ++ Q+ + + QTQ + +T ++ TI Sbjct: 873 HPTLSEASTAGRPTG---QSSPTSPSASPQETAAISRMAQTQ-RTRT-----SRGSDTIS 923 Query: 982 L--QADQLQHKLPQMPQLSIRHQKLTPLQQE--QAQPKPDVQHTQHPMVAKDRQLPTLMA 1037 L QA +P P SI LT Q E P + +++ LP A Sbjct: 924 LASQATDTFSTVPPTPP-SITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYA 982 Query: 1038 QPPQT-------VVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTAS 1090 T V +V T P +P+ + TP + + +S + T Sbjct: 983 SSASTGHTTPLHVTDASSVSTGHATPLPVTSPS--SVSTGHTTP---LPVTDTSSESTGH 1037 Query: 1091 QVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTS-PVTSISPIQASEKT--AVS 1147 P+ + S+ T G P T +S +T PVTS+S + T V+ Sbjct: 1038 VTPLPVTSFSSAST-----GDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVT 1092 Query: 1148 DILKMSLMEAQ----IDT-NVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTP 1202 D S A DT +V P +S TG A SLP T ++TP Sbjct: 1093 DTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTP 1152 Query: 1203 QQQKCRESCSS------PSTVGSSLTTRKIDP-----PAVPATGQFMRIQNVGQKKAEES 1251 S S+ P T SS++T P P+ +TG + A Sbjct: 1153 LHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTG 1212 Query: 1252 PAEIIIQAIPQYAIPCHSSSNVVVEPSGL-------LELNNFTSQQLDDEETAMEQDIDS 1304 A + H++S V PS L + + +S + + D S Sbjct: 1213 HATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSS 1272 Query: 1305 STEDGTEPSPSQSSAERS 1322 + T P P S++ S Sbjct: 1273 VSTGDTTPLPVTSTSSAS 1290 Score = 49.7 bits (117), Expect = 2e-05 Identities = 75/308 (24%), Positives = 125/308 (40%), Gaps = 36/308 (11%) Query: 113 TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVP---SGSIAT---- 165 T T++ A + P A TG V + TS+ ST +TP+P + S++T Sbjct: 3876 TSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHAT 3935 Query: 166 ---VKSPRPASPASN----VVVLPSGSTVYVKSV------SCSDEDEKPRKRRRTNSSS- 211 V SP AS V S ST + + S S D P T+S+S Sbjct: 3936 PLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSAST 3995 Query: 212 --SSPVVLKEVPKA----VVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265 ++P+ + + P+ TI S S + ++ H +P+ +T T Sbjct: 3996 GQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTST- 4054 Query: 266 PSTQTTNTTTQKVIIVTTSPS---STFVPNILSKSHNYAAVTKLVPTSVIA-STTQKPPV 321 S+ +T TT + T+S S +T +P + S + T L TS+ + ST P+ Sbjct: 4055 -SSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPL 4113 Query: 322 VITASQSSLVSNSSSGSSSSTP---SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKM 378 ++++ S+ +S S TP +P T +S P T+ + ++A+ Sbjct: 4114 AVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHT 4173 Query: 379 ASTRLPSP 386 ST P P Sbjct: 4174 RSTAAPIP 4181 Score = 35.4 bits (80), Expect = 0.37 Identities = 125/620 (20%), Positives = 214/620 (34%), Gaps = 80/620 (12%) Query: 310 SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQ 369 ++I + PV T S ++ + S+ +SS T + ++ ++ T S ++ AQ Sbjct: 33 TLITGSKTAAPVTSTGSTTATLEGQSTAASSRTSN---QDISASSQNHQTKSTETTSKAQ 89 Query: 370 GVSTSAIKMASTRLPSPK----SLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQ 425 T M ST SP + P ++ FP S L + + Sbjct: 90 -TDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPS----SVTNTLMMTSKTITMTTST 144 Query: 426 PSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPI 485 S + + ++ + T S V I Q S+ T+ TS++S Sbjct: 145 DSTLGNTEETSTAGTESSTPVT------SAVSITAGQEGQSRTTSWR-TSIQDTSASSQN 197 Query: 486 MVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545 S TT+ T T T T + P+ SPS+ + T T Sbjct: 198 HWTRST---QTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKT--------------- 239 Query: 546 SLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKN----VVT 601 + G+ +S++ S T T + MTS+ + TT G+T+ G PG+ V Sbjct: 240 ---SPSGETATSSLCSVTNTSM----MTSEK----ITVTTSTGSTL-GNPGETSSVPVTG 287 Query: 602 TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ 661 +L+ + P G PA + T ++ S I T Sbjct: 288 SLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPV 347 Query: 662 GKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKE-EPQNYTDSS 720 + VL P TV E T T S + N+ + K DS+ Sbjct: 348 TTSTVLSSPSGFNPSGTVSQETFPSGETTT----SSPSSVSNTFLVTSKVFRMPTSRDST 403 Query: 721 SSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL 780 +TE + S S + + + W ++ SP+ + +S+ + S Sbjct: 404 LGNTEETSLSV-SGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQS------ 456 Query: 781 ELQQTTVK--EKLESKP--RQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI 836 E +TT + E+ P Q L + K H+ S + S A + Sbjct: 457 EGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRL 516 Query: 837 TTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHV----------AQSQTATQTSVVV 886 T GT P + S S +P +P T H AQ+Q +T Sbjct: 517 VTGNPSTGTAGTIPRVPSKVSAIGEPGEP-TTYSSHSTTLPKTTGAGAQTQWTQETGTTG 575 Query: 887 KSIPASSPGAITHIMQQALS 906 +++ +S ++T +++ A S Sbjct: 576 EALLSSPSYSVTQMIKTATS 595 >gi|98986457 host cell factor 1 [Homo sapiens] Length = 2035 Score = 77.0 bits (188), Expect = 1e-13 Identities = 151/658 (22%), Positives = 246/658 (37%), Gaps = 153/658 (23%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPA------------------------SNVVVLPS 183 +T ++PT PVPS KSP PA+ A + + VLP+ Sbjct: 407 ATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT 466 Query: 184 --GSTVYVKSVSCSDEDEKPRK--------------RRRTNSSSSSPVVLKEVP---KAV 224 GS++ V + + + K R + + +PV + +P + V Sbjct: 467 VPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMV 526 Query: 225 VPVSKTITVPVSGSPKMSNIMQSIA-----NSLPPHMSPVKITFTKPSTQTTNTTTQKVI 279 VP + SP+MS + A +PP +P ++ TT K + Sbjct: 527 VPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSV------PAGTTIVKTM 580 Query: 280 IVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSS 339 VT P +T +P A K+ + V+ S P + + ++ V S S ++ Sbjct: 581 AVT--PGTTTLP----------ATVKVASSPVMVS---NPATRMLKTAAAQVGTSVSSAT 625 Query: 340 SSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS-TSAIKMASTRLPSPKSLVSAPTQILA 398 +++ PI V + + V++TV GV+ T + + +P +L+S ++++ Sbjct: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 Query: 399 QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGI----------KPT- 447 Q VQ A PV+ Q + PLP G KPT Sbjct: 686 VV----------QTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTT 734 Query: 448 -IQIKQESGVK-----IITQQVQPSKILPKPVT--ATLPTSS----NSPIMVVSSNG--- 492 I Q SG + V PS P T T+P S+ V SS G Sbjct: 735 IITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKS 794 Query: 493 --AIMTTKLVTTPTGTQATYTR--PTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLA 548 I+TTK++T+ TG A P ++ G+ T G+I+ VP Sbjct: 795 PITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMG-- 852 Query: 549 TLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGG 608 G ++++ VS +TT +VV+ TT G T G V T+L AGG Sbjct: 853 --GVRLVTPVTVSAVKPAVTT---------LVVKGTT--GVTTLGTVTGTVSTSLAGAGG 899 Query: 609 EKT-------IQTVPTGA-------KPAILTATRPITKMIVTQPKGIGS---TVQPAAKI 651 T I T+ T A P +T + T + T G+ + T+QP ++ Sbjct: 900 HSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTL--TAAGGLTTPTITMQPVSQP 957 Query: 652 IPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEG 709 ++ G + PV+ A+ +EQ VT +A++G +Q G Sbjct: 958 TQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVT--------IADSGQGDVQPG 1007 Score = 51.6 bits (122), Expect = 5e-06 Identities = 220/1140 (19%), Positives = 361/1140 (31%), Gaps = 182/1140 (15%) Query: 73 DERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPV 132 D + TTI + ++ +I G + + P T+ +A I + V Sbjct: 729 DGKPTTIITTTQASGAGTKPTILG--ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGV 786 Query: 133 PAETGSKEVVCYSYTSTTSTPTSTP------VPS--------GSIATVKSPRPASPASNV 178 + G K + T ++ T P VP G V P P + + Sbjct: 787 TSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTIL 846 Query: 179 VVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVP---------VSK 229 +P G V V+ S KP ++ L V V S Sbjct: 847 RTVPMGGVRLVTPVTVSAV--KPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSA 904 Query: 230 TITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTF 289 ++ P++ ++ + + N +S + T T TT T T + + T Sbjct: 905 SLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQ----- 959 Query: 290 VPNILSKSHNYAAVTKLVPTSVIAS-TTQKPPVVITASQS----------SLVSNSSSGS 338 V I + S A +P S++AS TT++P +T + S +LV ++ Sbjct: 960 VTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCE 1019 Query: 339 SSSTPSPIPNTVAVTAVVSSTP----------------SVVMSTVAQGVSTSAIKMASTR 382 + T + T V A + P S+V STV Q + S +++ S Sbjct: 1020 THETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQ-NGSVVRVCSNP 1078 Query: 383 L--PSPKSLVSAPTQILAQFPKQHQQS-PKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSP 439 + T + QH S P + ++ A S ++ Q+ + Sbjct: 1079 PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRA 1138 Query: 440 LPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKL 499 G I+I +G + Q S+ + +AT T + S G ++ + Sbjct: 1139 CAAGTPAVIRISVATGA-LEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197 Query: 500 VTTPTGTQATYTRPTV--------SPSI-----GRMAATPGAATYVKTTSGS-IITVVPK 545 P G + + SPSI GR + A +++ G+ + P Sbjct: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 Query: 546 SLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLN 605 + GG TT +T + P+ V Q + N TT N Sbjct: 1258 CESLQGGS-------PSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS-N 1309 Query: 606 AGGEKTI------QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYG 659 AG + + +T TG TAT G T QP G Sbjct: 1310 AGSAQRVCSNPPCETHETGTTHTATTATSN------------GGTGQPEG---------G 1348 Query: 660 QQGKTQVLIKPKPVTFQATVVSEQTRQLVTE------TLQQASRVAEAGNSSIQEG---- 709 QQ + T T +S L+ + T++ VA A + + Q G Sbjct: 1349 QQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALL 1408 Query: 710 --------------KEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAME 755 + T ++++ T + S+QD P D E E Sbjct: 1409 APFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAA-------SDQGEVESTQG 1461 Query: 756 TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESK-PRQPTIDLSQMAVPIQMTQE 814 S I + S + T+T+ + L TTV + P P + Q++ + Sbjct: 1462 DSVNI------TSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLP 1515 Query: 815 KRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVA 874 R +S S A++ AE ++ +T E A L + Q S + V Sbjct: 1516 PRQLLQSASTALMGES--AEVLSASQTPE-LPAAVDLSSTGEPSSGQESAGSAVVATVVV 1572 Query: 875 QSQTATQTSVVVKSIP----ASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDT 930 Q TQ+ V S+P A + T +M L+ + E + EE Sbjct: 1573 QPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQA 1632 Query: 931 LDPQTGLFYRSALTQ-----------SQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQT 979 L Q L + + Q +L E + Q T+ T+Q+ Sbjct: 1633 LAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELA 1692 Query: 980 IHLQADQLQHKLPQMPQLSIRHQKLTPLQQ------------EQAQPKPDVQHTQHPMVA 1027 +Q QLQ Q + + L P E A P P A Sbjct: 1693 ALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALL-PSTA 1751 Query: 1028 KDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQ 1087 + P+ PQ VV K + A + V+P P P E Q Sbjct: 1752 TESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQ 1811 Score = 39.3 bits (90), Expect = 0.025 Identities = 110/481 (22%), Positives = 172/481 (35%), Gaps = 131/481 (27%) Query: 426 PSPV-SHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT----LPTS 480 P+PV S P +SP P P +Q + G+ ++ Q P P T T LPT Sbjct: 414 PNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAA------PAPPTTTTIQVLPTV 467 Query: 481 SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII 540 S I V PT + T P V G A TT ++ Sbjct: 468 PGSSISV---------------PTAAR-TQGVPAVLKVTGPQA----------TTGTPLV 501 Query: 541 TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV 600 T+ P S A GK +T++P + +VV + +GT I P + + Sbjct: 502 TMRPASQA---GK---------APVTVTSLPAGVR---MVVPTQSAQGTVIGSSPQMSGM 546 Query: 601 TTLLNAGGEKTIQTVPTGAKPAILT--ATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVY 658 L A Q +P + P +L+ A I K + P G+T PA Sbjct: 547 AAL--AAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTP---GTTTLPAT--------- 592 Query: 659 GQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTD 718 V + PV V + TR L T Q + V+ A N+S + P Sbjct: 593 -------VKVASSPVM----VSNPATRMLKTAAAQVGTSVSSATNTSTR-----PIITVH 636 Query: 719 SSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSAT-STIK 777 S + T + Q+ Q V V+ + + T++ +S SA S + Sbjct: 637 KSGTVTVAQQA----QVVTTVVGG-----------VTKTITLVKSPISVPGGSALISNLG 681 Query: 778 ALLELQQTTVKEKLESKPRQPTIDLSQMAV-PI-QMTQEKRHSPESPSIAVVES---ELV 832 ++ + QT KP Q + Q + P+ Q+ Q K P + +V S + Sbjct: 682 KVMSVVQT--------KPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPT 733 Query: 833 AEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPAS 892 TT+ + GT+ P + V+ S T T+ ++K+IP S Sbjct: 734 TIITTTQASGAGTK------------------PTILGISSVSPSTTKPGTTTIIKTIPMS 775 Query: 893 S 893 + Sbjct: 776 A 776 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 76.6 bits (187), Expect = 1e-13 Identities = 231/1194 (19%), Positives = 370/1194 (30%), Gaps = 161/1194 (13%) Query: 100 VPLMPRLVPQTAFTVTANAVANAAIQ------HNASLPVPAETGSKEVVCYSYTSTTSTP 153 VP MP PQ T + Q + ++ + + TG ++ S T TP Sbjct: 1194 VPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTP 1253 Query: 154 TSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSS 213 + S T S P P + V P ++ + + KP + T +++S Sbjct: 1254 LLPATLTSSKPTASSGEPPRPTT--AVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311 Query: 214 PVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNT 273 A T+T+P + S + N P + + T +P+ +T Sbjct: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371 Query: 274 TTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKP---PVVITASQSSL 330 T T P++T + + T S + + P PV T+ ++ Sbjct: 1372 PTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATT 1431 Query: 331 VSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLV 390 + S ++ P+ +P + + V ST +V+ T AQ ++++ A T P + + Sbjct: 1432 TYPTPSHPETTLPTHVP-PFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTL 1490 Query: 391 SAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQI 450 A P S Q + + + S S P+ +P Sbjct: 1491 KATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPT 1550 Query: 451 KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT---PTGTQ 507 + + S P P T P + +SP SS G + T TT PT + Sbjct: 1551 STRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPF---SSTGPMTATSFKTTTTYPTPSH 1607 Query: 508 ATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKI 567 T PT P TP T + T + T ++ +GT Sbjct: 1608 PQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT-----------SASIHSMPTGTIPPP 1656 Query: 568 TTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTAT 627 TT+ T + T GT+ Q L N T + T T A T+T Sbjct: 1657 TTLKATGSTHTAPTMTLTTSGTS-QALSSLNTAKTSTSLHS----HTSSTHHAEATSTST 1711 Query: 628 RPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL 687 IT P G+ P VT T S + Sbjct: 1712 TNIT----PNPTSTGT-------------------------PPMTVTTSGTSQSRSSFST 1742 Query: 688 VTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQ-- 745 + S + P+ + S++S T + S+ PV H ++ Sbjct: 1743 AKTSTSLHSHTSST---------HHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRL 1793 Query: 746 --DWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLS 803 ++ H T+P V++ S T+T T T Sbjct: 1794 PTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTH 1853 Query: 804 QMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPS 863 + +P S S + TT + T A P+ + Q PS Sbjct: 1854 TVIIPTHTQMATSASIHSMPTGTIPPP------TTIKATGSTHTAPPMTPTTSGTSQSPS 1907 Query: 864 Q----------PQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSS-HTAFT 912 P T H + + T++ K + + H + S T FT Sbjct: 1908 SFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFT 1967 Query: 913 KHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQ---KLSQPPLEQTQLQVKTL 969 HS G+ + P T +++ T + Q PP + + T Sbjct: 1968 THSPPTGS-----SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTH 2022 Query: 970 QCFQTKQKQ-----TIH------------LQADQLQHKLPQMPQLSIRHQKLTPLQQEQA 1012 T Q +IH L+A H P M +T Q Sbjct: 2023 TVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPM--------TVTTSGTSQT 2074 Query: 1013 QPKPDVQHTQHPMVAKDRQLP-TLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQP 1071 ++ LP ++PP + + T QLP L A Q Sbjct: 2075 HSSFSTATASSSFISSSSWLPQNSSSRPPSSPI-------TTQLPHLSSATTPVSTTNQL 2127 Query: 1072 QTPQS-QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTS 1130 + S S P++ S P + S T +F P T ++ GS T Sbjct: 2128 SSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVS-APVHSTTLSSGSHSSLSTH 2186 Query: 1131 PVT---SISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSL 1187 P T S SP+ S A I + H I P + + T Sbjct: 2187 PTTASVSASPLFPSSPAA----------STTIRATLPHTISSPFTLSALLPISTVTVSPT 2236 Query: 1188 PSTHMVVAGMA-NSTPQQQKCRESC---SSPSTV--GSSLTTRKIDPPAVPATG 1235 PS+H+ + +A STP+ + SS ST +SLTTR VP +G Sbjct: 2237 PSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTR------VPTSG 2284 Score = 69.7 bits (169), Expect = 2e-11 Identities = 200/945 (21%), Positives = 297/945 (31%), Gaps = 144/945 (15%) Query: 426 PSPVSHQQ--QPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP--TSS 481 PSP S+ P Q+PL P + + SG +P P+P TA P TS Sbjct: 1238 PSPSSNHTPASPTQTPLLPATLTSSKPTASSG--------EP----PRPTTAVTPQATSG 1285 Query: 482 NSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541 P + S T PT TQAT TR T S A+P + ++T+ + +T Sbjct: 1286 LPPTATLRSTA--------TKPTVTQAT-TRATAS------TASPATTSTAQSTTRTTMT 1330 Query: 542 V-VPKSLATLGGKIISSNI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV 599 + P + T S+N + GTT TT P + + TTG T G P + Sbjct: 1331 LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPAS------TTGPTTPQPGQPTRPT 1384 Query: 600 VTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKI--- 656 T +T QT T T P T P GS V + T Sbjct: 1385 AT--------ETTQTRTT------TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHAT 1430 Query: 657 -VYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQN 715 Y + + F ++V+ T ++T T A A N S G P Sbjct: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPT--HAQMATSASNHSAPTGTIPPPT 1488 Query: 716 Y---------------TDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTI 760 T S +S SS S+ + +H S E+ ++ TI Sbjct: 1489 TLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLH---SHTSSTHHPEVTPTSTTTI 1545 Query: 761 IYQDVSSESQSATSTIKALLELQQ----TTVKEKLESKPRQPTIDLSQMAVPIQMTQEKR 816 S+ +++ + + + TT S P T ++ + T Sbjct: 1546 TPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTP 1605 Query: 817 HSPESP---SIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHV 873 P++ + + LV T T ++A S S P P TL + Sbjct: 1606 SHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATS--ASIHSMPTGTIPPPTTL-KAT 1662 Query: 874 AQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDP 933 + TA ++ + T +L SHT+ T H+E T + T Sbjct: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPT--- 1719 Query: 934 QTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQ 993 TG + T S + S K ++H H P+ Sbjct: 1720 STGTPPMTVTTSGTSQSRSSFS-----------------TAKTSTSLHSHTSSTHH--PE 1760 Query: 994 MPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMA--QPPQTVVQVLA--- 1048 + S +TP P H A +LPT PP + + Sbjct: 1761 VTSTST--TSITPNHTSTGTRTP----VAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814 Query: 1049 -VKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKIT 1107 T+ Q P+ P + P SL S + T +S+ + Sbjct: 1815 VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMAT-SASIHSMP 1873 Query: 1108 FEGRQPPTVTKITGGS-SVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHM 1166 PPT K TG + + P +T + S +S TA K S ++ H Sbjct: 1874 TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTA-----KTSTSLPYHTSSTHHP 1928 Query: 1167 IVDPPKKALATSMLTGEAGSLPSTHMVVAG-------MANSTPQQQKCRESCSSPSTVGS 1219 V P T T P H A +P S + P T S Sbjct: 1929 EVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATS 1988 Query: 1220 SLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPC--HSSSNVVVEP 1277 TT P+ P T + S +II Q A HS+ V P Sbjct: 1989 FQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPP 2048 Query: 1278 SGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS 1322 L+ T TA + +S T S S ++A S Sbjct: 2049 PTTLKATGST-------HTAPPMTVTTSGTSQTHSSFSTATASSS 2086 Score = 63.9 bits (154), Expect = 1e-09 Identities = 120/479 (25%), Positives = 178/479 (37%), Gaps = 70/479 (14%) Query: 110 TAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSP 169 T T +A +A H+ +P T + ST + P TP SG T +SP Sbjct: 1854 TVIIPTHTQMATSASIHS----MPTGTIPPPTTIKATGSTHTAPPMTPTTSG---TSQSP 1906 Query: 170 RPASPASNVVVLP--SGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVV-LKEVPKAVVP 226 S A LP + ST + + S + P+ T++ + +PV + +P Sbjct: 1907 SSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPK---HTSTGTRTPVAHTTSASSSRLP 1963 Query: 227 VSKTITVPVSGSPKMSNIMQSIANS----------------LPPHMSPVKITFTKPSTQT 270 T P +GS S+ A S LP H+ P + PST T Sbjct: 1964 TPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHT 2023 Query: 271 TNTTTQKVIIVTTS----PSSTFVPNILSKS--HNYAAVTKLVPTSVIASTTQKPPVVIT 324 TT + + S P+ T P K+ + A V TS T+Q T Sbjct: 2024 VIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTS---GTSQTHSSFST 2080 Query: 325 ASQSSLVSNSSSG---SSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381 A+ SS +SSS +SSS P P T + + S+T V ST Q ++S+ Sbjct: 2081 ATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPV--STTNQ--------LSSS 2130 Query: 382 RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQS--- 438 PSP SAP+ + + P H SP+ V + A + S Sbjct: 2131 FSPSP----SAPSTVSSYVPSSHS-SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185 Query: 439 -PLPPGIKPTIQIKQESGVKIITQQVQPSKIL-PKPVTATLPTSSNSPIMVVSSNGAIMT 496 P + + + P I P ++A LP S+ + SS+ A T Sbjct: 2186 HPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245 Query: 497 TKLVTTPTGTQATYTRP------TVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLAT 549 +TP T +T+T P T S S P + +V TSG +T +P S T Sbjct: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVP-TSGFVSLTSG--VTGIPTSPVT 2301 Score = 49.3 bits (116), Expect = 2e-05 Identities = 66/279 (23%), Positives = 117/279 (41%), Gaps = 28/279 (10%) Query: 88 SSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYT 147 SSS W + P + Q +A + Q ++S P+ + V Y + Sbjct: 2089 SSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFS-PSPSAPSTVSSYVPS 2147 Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASN-----VVVLPSGSTVYVKSVSCSDEDEKPR 202 S +S TS+P S + V +P ++ S+ + P+ ++V + S Sbjct: 2148 SHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTT 2207 Query: 203 KRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262 R + SSP L A++P+S T+TV SP S+ + S + P T Sbjct: 2208 IRATLPHTISSPFTLS----ALLPIS-TVTV----SPTPSSHLASSTIAFPSTPRTTAST 2258 Query: 263 FTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVV 322 T P+ + +TT++ + T P+S FV + + +PTS + + T + P Sbjct: 2259 HTAPAFSSQSTTSRSTSLTTRVPTSGFV--------SLTSGVTGIPTSPVTNLTTRHPGP 2310 Query: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS 361 T S ++ SS + STP+ P V+++ + TP+ Sbjct: 2311 -TLSPTTRFLTSSLTAHGSTPASAP----VSSLGTPTPT 2344 Score = 45.4 bits (106), Expect = 4e-04 Identities = 73/304 (24%), Positives = 108/304 (35%), Gaps = 53/304 (17%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSG--------STVYVKSVSCSDEDE 199 S STPT T P ++ S A P + V SG ST S S Sbjct: 2037 SIHSTPTGTVPPPTTLKATGSTHTAPP---MTVTTSGTSQTHSSFSTATASSSFISSSSW 2093 Query: 200 KPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP--HMS 257 P+ SS L + A PVS T + S SP S S +S P H S Sbjct: 2094 LPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPS--APSTVSSYVPSSHSS 2151 Query: 258 PVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQ 317 P + PS T+++ + TT S + + + + L P+S ASTT Sbjct: 2152 PQT---SSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTI 2208 Query: 318 KPPVVITASQ-----------SSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS----- 361 + + T S + VS + S +S+ P+T TA + P+ Sbjct: 2209 RATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQS 2268 Query: 362 -----------------VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404 V +++ G+ TS + +TR P P +S T+ L H Sbjct: 2269 TTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGP--TLSPTTRFLTSSLTAH 2326 Query: 405 QQSP 408 +P Sbjct: 2327 GSTP 2330 >gi|56549696 E1A binding protein p400 [Homo sapiens] Length = 3122 Score = 75.5 bits (184), Expect = 3e-13 Identities = 158/693 (22%), Positives = 243/693 (35%), Gaps = 112/693 (16%) Query: 409 KQQLYQVQQQTQQQVAQPSPVSHQQQPQ-QSPLPPGIKPTIQIKQ-ESGVKIITQQVQPS 466 K+ L Q+ Q VAQP P Q P Q P PP +P Q +G + Q QP Sbjct: 2489 KKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQ 2548 Query: 467 -KILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAAT 525 + P+PV A + P + + A++ + T+ TGT + + + +A Sbjct: 2549 PQTQPQPVQA---PAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGV 2605 Query: 526 PGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTT 585 P AAT+ V P +L T GG + + + + P T+ P+++ + T Sbjct: 2606 P-AATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQ 2664 Query: 586 GKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTV 645 G + + VVTT L +QT P + AT V P G T+ Sbjct: 2665 GV-RAVTSVTASAVVTTNLT-----PVQTPARSLVPQVSQATG------VQLP---GKTI 2709 Query: 646 QPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSS 705 PA FQ +Q +Q + QQ + Sbjct: 2710 TPA-------------------------HFQLLRQQQQQQQQQQQQQQQQQQ-------- 2736 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDV 765 Q+ +++ Q +++S + Q +Q + A + EH I M+ Sbjct: 2737 -QQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLT-PEHLIKMQ---------- 2784 Query: 766 SSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIA 825 K L++ + +S P QPT V +Q +Q + +SP + Sbjct: 2785 -----------KQKLQMPPQPPPPQAQSAPPQPTAQ-----VQVQTSQPPQQ--QSPQLT 2826 Query: 826 VVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV 885 V + +T GT VA + P Q Q + Q Sbjct: 2827 TVTAPRPGALLT------GTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPP 2880 Query: 886 VKSIPA---SSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSA 942 V S+PA SSPG T M A S A + + G T+ Q + Sbjct: 2881 VVSVPAAVVSSPGVTTLPMNVAGIS-VAIGQPQKAAG---------QTVVAQPVHMQQLL 2930 Query: 943 LTQSQSAKQQKLSQPPLEQTQLQVK---TLQCFQTKQKQTIHLQADQLQHKLPQMPQLSI 999 + Q+ +QQK QP Q V+ T Q T Q A Q K + Sbjct: 2931 KLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPIS 2990 Query: 1000 RHQKLTPLQQEQAQPK----PDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQL 1055 + QKL QQ Q Q + P V Q P+ + + PQTV A QQ+ Sbjct: 2991 QAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQV 3050 Query: 1056 PKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088 + ++ VQ + Q Q+ AS+ QT Sbjct: 3051 QMIPAVTATAQV-VQQKLIQQQVVTTASAPLQT 3082 Score = 71.6 bits (174), Expect = 5e-12 Identities = 126/562 (22%), Positives = 213/562 (37%), Gaps = 58/562 (10%) Query: 267 STQTTNTTTQKVIIVTTS--PSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVIT 324 ++ T + VI+ T + P++TF +S N + + P ++ P V+ Sbjct: 2586 TSMPTGAVSGNVIVNTIAGVPAATF------QSINKRLASPVAPGALTTPGGSAPAQVVH 2639 Query: 325 ASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMA----- 379 S + ++ S + T V AV S T S V++T V T A + Sbjct: 2640 TQPPPRAVGSPATATPDLVS-MATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQ 2698 Query: 380 --STRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQT-----QQQVAQPSPVSHQ 432 +LP K++ A Q+L Q +Q QQ +QQ Q QQQ QQQ S V Sbjct: 2699 ATGVQLPG-KTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVP 2757 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492 Q Q+ P IK ++ E +K+ Q++Q P P + P + + V +S Sbjct: 2758 QIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQP 2817 Query: 493 AIMTTKLVTTPTGTQ--ATYTRPTVSP-SIGRMAATPGAATYVKTTSGSIITVVPK--SL 547 + +TT T + A T TV+ + R+ P T G + T P+ + Sbjct: 2818 PQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVP---TSQLQAQGQMQTQAPQPAQV 2874 Query: 548 ATLGGKIISSNIVSGTTTKITTIPM-TSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNA 606 A ++S ++ +TT+PM + +V + Q G T+ P L Sbjct: 2875 ALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQ 2934 Query: 607 GGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQV 666 + + + A + IT +T P A + T+ + + Q Sbjct: 2935 QAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQK 2994 Query: 667 LIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTES 726 L + V Q V + + +QQ + VA SIQ+ Q + + + T++ Sbjct: 2995 LAGAQQVQTQIQVAK------LPQVVQQQTPVA-----SIQQVASASQQASPQTVALTQA 3043 Query: 727 SQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTT 786 + + Q Q + V A+ A +I Q V + + + T A Q Sbjct: 3044 TAAGQQVQMIPAVTAT----------AQVVQQKLIQQQVVTTASAPLQTPGAPNPAQ--- 3090 Query: 787 VKEKLESKPRQPTIDLSQMAVP 808 V +S +QP + QM VP Sbjct: 3091 VPASSDSPSQQPKL---QMRVP 3109 Score = 41.2 bits (95), Expect = 0.007 Identities = 48/167 (28%), Positives = 69/167 (41%), Gaps = 25/167 (14%) Query: 382 RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ-QVAQPSPVSHQQQPQQSPL 440 RLP P + +A QF +Q Q Q Q+ +TQQ V P+P S Q P+ Sbjct: 559 RLP-PAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPS-----SQLPI 612 Query: 441 PPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT-------------LPTSSNSPIMV 487 PP + + + K+ Q Q S LP+ V +T LPTSS S + Sbjct: 613 PPSQPAQLALHVPTPGKVQVQASQLSS-LPQMVASTRLPVDPAPPCPRPLPTSSTSSLAP 671 Query: 488 VSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534 VS +G + ++P ++ T +SP R TPG T Sbjct: 672 VSGSGP-GPSPARSSPVNRPSSATNKALSPVTSR---TPGVVASAPT 714 Score = 41.2 bits (95), Expect = 0.007 Identities = 65/325 (20%), Positives = 107/325 (32%), Gaps = 18/325 (5%) Query: 945 QSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQAD-QLQHKLPQMPQLSIRHQK 1003 Q Q +QQ+ Q +Q Q Q + Q T Q Q +Q Q ++ + +L+ H Sbjct: 2722 QQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLI 2781 Query: 1004 LTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPN 1063 Q+ Q P+P Q Q+ +QPPQ L T + L Sbjct: 2782 KMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTT 2841 Query: 1064 QPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKI---T 1120 + V T L A + QT + + V + P VT + Sbjct: 2842 VANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNV 2901 Query: 1121 GGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSML 1180 G SV + P + ++ + +LK+ Q ++ P A + Sbjct: 2902 AGISV-AIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGP--AAVQQKI 2958 Query: 1181 TGEAGSLPSTHMVVAGMAN--------STPQQQKCRESCSSPSTVGSSLTTRKIDPPAVP 1232 T + + P VA A +TP Q + + V + + K+ P V Sbjct: 2959 TAQQITTPGAQQKVAYAAQPALKTQFLTTPISQ--AQKLAGAQQVQTQIQVAKL-PQVVQ 3015 Query: 1233 ATGQFMRIQNVGQKKAEESPAEIII 1257 IQ V + SP + + Sbjct: 3016 QQTPVASIQQVASASQQASPQTVAL 3040 Score = 37.7 bits (86), Expect = 0.074 Identities = 65/274 (23%), Positives = 102/274 (37%), Gaps = 30/274 (10%) Query: 991 LPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVK 1050 LP + S+R +++ ++ A D Q Q P VA Q P QPP Q Sbjct: 2472 LPPIQVASLRAERIAKEKKALA----DQQKAQQPAVA---QPPPPQPQPPPPPQQ----- 2519 Query: 1051 TTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEG 1110 LP+ Q A +QP PQ Q + A QP IT G S + Sbjct: 2520 PPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTI 2579 Query: 1111 RQPPTVTKI-TGGSSVPKLTSPVTSI--SPIQASEKTAVSDILKMSLMEAQIDTNVEHMI 1167 + T T + TG S + + + + + Q+ K S + +L + + Sbjct: 2580 KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVH 2639 Query: 1168 VDPPKKALAT-SMLTGEAGSLPSTHMVVAGMA---------NSTPQQQKCRESCSSPS-T 1216 PP +A+ + + T + S+ +T V A + N TP Q R S Sbjct: 2640 TQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQA 2699 Query: 1217 VGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEE 1250 G L + I PA Q +R Q Q++ ++ Sbjct: 2700 TGVQLPGKTI----TPAHFQLLRQQQQQQQQQQQ 2729 Score = 34.7 bits (78), Expect = 0.62 Identities = 51/247 (20%), Positives = 90/247 (36%), Gaps = 33/247 (13%) Query: 992 PQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTL------------MAQP 1039 PQ QL+ + Q P + P+ +LP AQ Sbjct: 520 PQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQ 579 Query: 1040 PQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQ 1099 PQ V+ +T Q+P Q PN P P P SQ+ +P S Q A V P Sbjct: 580 PQ----VVEAQTQLQIPVKTQQPNVP----IPAPPSSQLPIPPSQPAQLALHVPTP---- 627 Query: 1100 GSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQI 1159 K+ + Q ++ ++ + +P +P P+ S ++++ + + Sbjct: 628 ----GKVQVQASQLSSLPQMVASTRLPVDPAPPCP-RPLPTSSTSSLAPVSGSGPGPSPA 682 Query: 1160 DTNVEHMIVDPPKKALA--TSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTV 1217 ++ + KAL+ TS G S P+ A N+T Q +++ + T+ Sbjct: 683 RSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPA--QNATSSQDSSQDTLTEQITL 740 Query: 1218 GSSLTTR 1224 + + R Sbjct: 741 ENQVHQR 747 >gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial [Homo sapiens] Length = 1063 Score = 74.7 bits (182), Expect = 5e-13 Identities = 126/560 (22%), Positives = 210/560 (37%), Gaps = 63/560 (11%) Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204 S TST ST STP + SI T ++ ++P+ + + +T + + S + + R Sbjct: 83 SITSTESTSHSTPPFTSSITTNETTSHSTPSFTTSITKTKTTSH-STPSFTSSNSITDSR 141 Query: 205 RRTNSSSSSPVVLKEVPKAVVP--VSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262 + +S V E+ P +S IT + S +I +++ + + Sbjct: 142 SHSTPPFTSSVTTPEMTSHNTPSFMSSIITTETTSHSTPSFTSSTIHSTVSSSTTAITSP 201 Query: 263 FTKPSTQTTNTTTQKVIIVTTSPSS---TFVPNILSKSHNYAAVTKL--VPTSVIASTTQ 317 FT T T+T + + T P++ T P LS S + T L +PT + + T Sbjct: 202 FTTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLSLSTSTSLTTTTDLPSIPTDISSLPT- 260 Query: 318 KPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVT-AVVSSTPSVVMSTVAQGVSTSAI 376 P+ I +S S+ S +S S T SP +TV T +TP ST + Sbjct: 261 --PIHIISSSPSIQSTETS-SLVGTTSPTMSTVRATLRSTENTPISSFSTSIVVTPETPT 317 Query: 377 KMASTRLPSPKSLVSAPTQILAQFPKQ-------HQQSPKQQLYQVQQQTQQQVAQPSPV 429 A L S ++P F H +P L ++ +Q P P Sbjct: 318 TQAPPVLMSATGTQTSPVPTTVTFGSMDSSTSTLHTLTPSTALSKIMSTSQ----FPIPS 373 Query: 430 SHQQQPQQSPLPPGIKPTIQIKQE-------------------------SGVKIITQQVQ 464 +H Q +P P ++ ++ E S I Sbjct: 374 THSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSS 433 Query: 465 PSKILPKPVTA-TLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSP-SIGRM 522 PS PV A T+ + +SP + + N + + + + T T PT S + Sbjct: 434 PSSASITPVFATTIHSVPSSPYIFSTENVGSASITAFPSLSSSSTTSTSPTSSSLTTALT 493 Query: 523 AATPGAATYVKTTS---GSI-ITVVPKSLATLGGKI-ISSNIVSGTTTKITTIPMTSK-- 575 TP + + +T+ G+I IT+VP S ++ S+ S TT +T P T++ Sbjct: 494 EITPFSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMV 553 Query: 576 --PNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKM 633 P+ I +Q T + ++ + + NA TVPT + T+TR T Sbjct: 554 TCPSSISMQTTLATHMDTSSMTPESESSIIPNASSSTGTGTVPTN---TVFTSTRLPTSE 610 Query: 634 IVTQPKGIGSTVQPAAKIIP 653 + T P IP Sbjct: 611 TWLSNNSVIPTPLPGVSTIP 630 Score = 57.4 bits (137), Expect = 9e-08 Identities = 151/705 (21%), Positives = 256/705 (36%), Gaps = 144/705 (20%) Query: 267 STQTTNTTTQKVI--IVTTSPSSTFVPNILSK-------SHNYAAVTKLVPTSVIAS-TT 316 +T+TT+ +T IVTT +S P S H+ T L+ TS + S +T Sbjct: 1 TTETTSRSTPGFTSSIVTTETTSPHTPGFTSSITTTETIPHSTPTFTSLITTSEMTSHST 60 Query: 317 QKPPVVITASQSSLVSNSSSGSS-SSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA 375 IT ++S+ S S SS +ST S +T T+ +++ + ST + S + Sbjct: 61 PSLTFSITTTKSTSYSPPSFTSSITSTESTSHSTPPFTSSITTNETTSHSTPSFTTSITK 120 Query: 376 IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP 435 K S PS S S + H P V P SH Sbjct: 121 TKTTSHSTPSFTSSNSITDS------RSHSTPP----------FTSSVTTPEMTSHN--- 161 Query: 436 QQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPI-MVVSSNGAI 494 T S I + + + P+ ++S I VSS+ Sbjct: 162 ------------------------TPSFMSSIITTETTSHSTPSFTSSTIHSTVSSSTTA 197 Query: 495 MTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKI 554 +T+ T TG +T + P+ +T + TT S+ T+ P SL+T Sbjct: 198 ITSPFTTAETGVTSTPSSPS------------SLSTDIPTT--SLRTLTPLSLSTSTSLT 243 Query: 555 ISSNIVSGTTTKITTIP-----MTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609 ++++ S T I+++P ++S P++ + ++ GTT P + V L + Sbjct: 244 TTTDLPS-IPTDISSLPTPIHIISSSPSIQSTETSSLVGTT---SPTMSTVRATLRSTEN 299 Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYG-QQGKTQVLI 668 I + T ++T P T+ G+ P +PT + +G T L Sbjct: 300 TPISSFSTS---IVVTPETPTTQAPPVLMSATGTQTSP----VPTTVTFGSMDSSTSTLH 352 Query: 669 KPKPVTFQATVVSEQTRQLV---TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST- 724 P T + ++S + + TLQ + S + +++T S+S+ Sbjct: 353 TLTPSTALSKIMSTSQFPIPSTHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNA 412 Query: 725 ------------------ESSQSSQDSQPV----VHVIASRRQDWSEHEI---AMETSPT 759 SS SS PV +H + S +S + ++ P+ Sbjct: 413 ILTSFSTIIWSSTPTIIMSSSPSSASITPVFATTIHSVPSSPYIFSTENVGSASITAFPS 472 Query: 760 IIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSP 819 + +S S +++S AL E+ + + P TI ++ + P Sbjct: 473 LSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGTITITIV-------------P 519 Query: 820 ESPSIAVVESELVAEYITTERTDEGTE--VAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQ 877 SP+ VE + +TE T T FP + P S Q TL H+ S Sbjct: 520 ASPTDPCVEMD-----PSTEATSPPTTPLTVFPFTTEMVTCPSSISM-QTTLATHMDTSS 573 Query: 878 TATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEE 922 ++ + +SS G T + ++T FT S L T E Sbjct: 574 MTPESESSIIPNASSSTGTGT------VPTNTVFT--STRLPTSE 610 Score = 54.3 bits (129), Expect = 8e-07 Identities = 103/501 (20%), Positives = 195/501 (38%), Gaps = 76/501 (15%) Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPA-----SNVVVLPSGSTVYVKSVSCSDEDEKPR 202 +T +T STP + SI T ++ P +P + +P + + ++ S+ Sbjct: 1 TTETTSRSTPGFTSSIVTTETTSPHTPGFTSSITTTETIPHSTPTFTSLITTSEM----- 55 Query: 203 KRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262 +S S+P + ++ T P S + +++ +S ++S PP S + Sbjct: 56 ------TSHSTP----SLTFSITTTKSTSYSPPSFTSSITST-ESTSHSTPPFTSSI--- 101 Query: 263 FTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQK-PPV 321 TTN TT +T +T + + SH+ + T S+ S + PP Sbjct: 102 -------TTNETTSH----STPSFTTSITKTKTTSHSTPSFTS--SNSITDSRSHSTPPF 148 Query: 322 VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAS- 380 + + + S++ TPS + + + STPS ST+ VS+S + S Sbjct: 149 TSSVTTPEMTSHN-------TPSFMSSIITTETTSHSTPSFTSSTIHSTVSSSTTAITSP 201 Query: 381 --TRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS-PVSHQQQPQQ 437 T S S+P+ + P ++ PS P P Sbjct: 202 FTTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLSLSTSTSLTTTTDLPSIPTDISSLPTP 261 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497 + P+IQ + S + T + V ATL ++ N+PI + +T Sbjct: 262 IHIISS-SPSIQSTETSSLVGTTSPTMST------VRATLRSTENTPI-------SSFST 307 Query: 498 KLVTTPTGTQATYTRPTVSPSIG-RMAATPGAATY--VKTTSGSIITVVPKSLATLGGKI 554 +V TP T T P + + G + + P T+ + +++ ++ T+ P +T KI Sbjct: 308 SIVVTPE-TPTTQAPPVLMSATGTQTSPVPTTVTFGSMDSSTSTLHTLTP---STALSKI 363 Query: 555 ISSNIVSGTTTKITTIPMT-SKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQ 613 +S++ +T +T+ T S P++ +T + TT G +L + Sbjct: 364 MSTSQFPIPSTHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILT-----SFS 418 Query: 614 TVPTGAKPAILTATRPITKMI 634 T+ + P I+ ++ P + I Sbjct: 419 TIIWSSTPTIIMSSSPSSASI 439 Score = 50.8 bits (120), Expect = 8e-06 Identities = 108/491 (21%), Positives = 182/491 (37%), Gaps = 76/491 (15%) Query: 77 TTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAET 136 T + S P+S S I L L P L T+ ++T + +SLP P Sbjct: 207 TGVTSTPSSPSSLST-DIPTTSLRTLTP-LSLSTSTSLTTTTDLPSIPTDISSLPTPIHI 264 Query: 137 GSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRP---ASPASNVVVLPSGSTVYVKSVS 193 S S +++ T++P S AT++S +S ++++VV P T V Sbjct: 265 ISSSPSIQSTETSSLVGTTSPTMSTVRATLRSTENTPISSFSTSIVVTPETPTTQAPPVL 324 Query: 194 CSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLP 253 S + +SPV ++ + T+ ++ S +S IM + +P Sbjct: 325 MS-----------ATGTQTSPVPTTVTFGSMDSSTSTLHT-LTPSTALSKIMSTSQFPIP 372 Query: 254 P-HMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNIL----------------SK 296 H S ++ T + PS QT+ T+T + + + ST IL S Sbjct: 373 STHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSS 432 Query: 297 SHNYAAVTKLVPTSV--------IASTTQKPPVVITA----SQSSLVSNSSSGSSSSTP- 343 S + A++T + T++ I ST ITA S SS S S + SS +T Sbjct: 433 SPSSASITPVFATTIHSVPSSPYIFSTENVGSASITAFPSLSSSSTTSTSPTSSSLTTAL 492 Query: 344 --------------SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389 +P P T+ +T V +S + +TS T P + Sbjct: 493 TEITPFSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEM 552 Query: 390 VSAPTQI-----LAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP-- 442 V+ P+ I LA +P+ + + + P + + P Sbjct: 553 VTCPSSISMQTTLATHMDTSSMTPESESSIIPNASSSTGTGTVPTNTVFTSTRLPTSETW 612 Query: 443 ----GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTK 498 + PT GV I ++PS LP + + ++ SP +S ++ TT+ Sbjct: 613 LSNNSVIPT----PLPGVSTIPLTMKPSSSLPTILRTSSKSTHPSPPTARTSETSVATTQ 668 Query: 499 LVTTPTGTQAT 509 TT T + T Sbjct: 669 TPTTLTTRRTT 679 Score = 44.3 bits (103), Expect = 8e-04 Identities = 61/247 (24%), Positives = 95/247 (38%), Gaps = 21/247 (8%) Query: 137 GSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSD 196 GS + + S++ST +++P S + P S S P T+ + V S Sbjct: 463 GSASITAFPSLSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASP 522 Query: 197 EDEKPRKRRRTNSSSSSPVVLKEVPKAVVP-VSKTITVPVSGSPKMSNIMQSIANSLPPH 255 D P ++ ++SP P V P ++ +T P S S + + +S+ P Sbjct: 523 TD--PCVEMDPSTEATSPPT---TPLTVFPFTTEMVTCPSSISMQTTLATHMDTSSMTPE 577 Query: 256 MSPVKITFTKPSTQTTNTTTQKVIIVTTSPSS-TFVPNILSKSHNYAAVTKLVPTSVIAS 314 I ST T T V T P+S T++ N N T L S I Sbjct: 578 SESSIIPNASSSTGTGTVPTNTVFTSTRLPTSETWLSN------NSVIPTPLPGVSTIP- 630 Query: 315 TTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTS 374 T KP SSL + + S S+ PSP + T+V ++ ++T TS Sbjct: 631 LTMKP-------SSSLPTILRTSSKSTHPSPPTARTSETSVATTQTPTTLTTRRTTPITS 683 Query: 375 AIKMAST 381 + ST Sbjct: 684 WMTTQST 690 >gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial [Homo sapiens] Length = 909 Score = 74.3 bits (181), Expect = 7e-13 Identities = 126/626 (20%), Positives = 244/626 (38%), Gaps = 60/626 (9%) Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204 S T+T +T STP + SI+T ++ ++P+ ++ + +T + + S + Sbjct: 34 SITTTETTSHSTPSFTSSISTTETTSHSTPSFTSLITITETTSH-STPSYTTSITTTETP 92 Query: 205 RRTNSSSSSPVVLKEVPKAVVP-VSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITF 263 + S ++ + E P P + +IT + S + SI + S T Sbjct: 93 SHSTPSYTTSITTTETPSHSTPSFTSSITTTETTSHSTPSFTSSIRTTETTSYSTPSFTS 152 Query: 264 TKPSTQTTNTTTQKVI--IVTTSPSSTFVPNILSK-------SHNYAAVTKLVPTSVIA- 313 + T+TT+ +T I I TT S+ P+ S SH+ T + T+ Sbjct: 153 SNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTETTS 212 Query: 314 -STTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 ST + T +S + S + S +++ +P +T + T+++++T + ST + Sbjct: 213 HSTPSFTSSITTTETTSHDTPSFTSSITTSETPSHSTPSSTSLITTTKTTSHSTPS---F 269 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 TS+I T S S S+ T + + +S + + + + S ++ Sbjct: 270 TSSITTTETTSHSAHSFTSSIT--TTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTT 327 Query: 433 QQPQQS-PLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS---NSPIMVV 488 + S P T + V P+ + P ++ +PT+S +P V Sbjct: 328 ETTSHSTPSFSSSITTTETXXXXXXXTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVG 387 Query: 489 SSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLA 548 +S TT + PT TR + S + +T ++ V TTS ++ TV Sbjct: 388 TSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTE-TSSLVGTTSPTMSTV------ 440 Query: 549 TLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGG 608 + +I + +S +T I IP T V+ TG T+ P VT Sbjct: 441 RMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTS----PAPTTVTFGSTDSS 496 Query: 609 EKTIQTV-PTGAKPAILTATRPITKMIVTQPKGIGSTVQ--PAAKIIPTKIVYGQQGKTQ 665 T+ T+ P+ A I++ ++ V P ST+Q P+ + T + + T+ Sbjct: 497 TSTLHTLTPSTALSTIVSTSQ------VPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTE 550 Query: 666 VLIKPKP-----VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEP------- 713 + +T +T++ T ++ + ++ + +++I P Sbjct: 551 SFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTEN 610 Query: 714 ------QNYTDSSSSSTESSQSSQDS 733 + SSS+T S+ S+ S Sbjct: 611 VGSASITGFPSLSSSATTSTSSTSSS 636 Score = 63.2 bits (152), Expect = 2e-09 Identities = 121/591 (20%), Positives = 214/591 (36%), Gaps = 88/591 (14%) Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS--GSIAT 165 P + ++T + + S ET S ++ + TT+ TS PS SI T Sbjct: 182 PSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHDTPSFTSSITT 241 Query: 166 VKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV 225 ++P ++P+S ++ + +T + S +S +SS + Sbjct: 242 SETPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTETTSHNTR 301 Query: 226 PVSKTITVPVSGSPKMSNIMQSI------ANSLPPHMSPVKITFTKPS----------TQ 269 + +IT + S ++ SI ++S P S + T T T Sbjct: 302 SFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETXXXXXXXTSETAVTP 361 Query: 270 TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKL--VPTSVIASTTQKPPVVITASQ 327 T T + + T+ T P+ + S + T +PT + T+ + + S Sbjct: 362 TPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSI 421 Query: 328 SSLVSNSSSGSSSSTPSPIPNTVAVT------------AVVSSTPSVV--MSTVAQGVST 373 S ++S G++S T S + T+ +T V+ TP+ + T A G T Sbjct: 422 QSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQT 481 Query: 374 SAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQ 433 S P+P ++ T + H +P L + +Q P P +H Sbjct: 482 S---------PAPTTVTFGSTD--SSTSTLHTLTPSTALSTIVSTSQ----VPIPSTHSS 526 Query: 434 QPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGA 493 Q +P P ++ ++ E + T+ + + + + +S+ + IM S + A Sbjct: 527 TLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSA 586 Query: 494 IMTTKLVTT----PTGTQATYTRPTVSPSI-GRMAATPGAATYVKTTSGSIIT----VVP 544 +T TT P+ T S SI G + + A T +TS S+ T + P Sbjct: 587 SITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITP 646 Query: 545 KSLATL------GGKII-----------------SSNIVSGTTTKITTIPMTSK----PN 577 S +L G I S+ S TT +T P T++ P Sbjct: 647 FSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPT 706 Query: 578 VIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATR 628 I +Q T + ++ + NA TVPT + T+TR Sbjct: 707 SISIQTTLTTYMDTSSMMPESESSISPNASSSTGTGTVPTN---TVFTSTR 754 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 73.6 bits (179), Expect = 1e-12 Identities = 171/906 (18%), Positives = 313/906 (34%), Gaps = 109/906 (12%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASN------VVVLPSGSTVYVKSVSCSDEDEK 200 TSTT + P + A +PRP+ P ++ + + +TV K + +++ Sbjct: 104 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 163 Query: 201 PRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVK 260 + +T S+ + + K K + P SK + P +PK + A + P +P Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP---TPKAETTTKGPALTTPKEPTPT- 219 Query: 261 ITFTKPSTQT----TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 T +P++ T T TT + P+ T + + A T P A TT Sbjct: 220 -TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP----APTT 274 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSP-IPNTVAVTAVVSSTPSVVMSTVAQGVSTSA 375 K P T + + + S+ ++ P+P P A T P+ +T Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP---TTPK 331 Query: 376 IKMASTRLPSP----KSLVSAPTQILAQFPKQ-HQQSPKQQL-YQVQQQTQQQVAQPSPV 429 +T+ P+P + +AP + PK+ +PK+ ++ + +P+P Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391 Query: 430 SHQQQP--QQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT--ATLPTSSNSPI 485 + + P + P P K +E + + P P T PT+ P Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451 Query: 486 MVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545 A TTK T + T P + TP TT + P+ Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP-------TTPEKLAPTTPE 504 Query: 546 SLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLN 605 A + ++ T P + P T P Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564 Query: 606 AGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK-IIPTKIVYGQQGKT 664 ++T T P G P L P T PK +PA K + PT ++ + Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAP------TTPK------KPAPKELAPTTT---KEPTS 609 Query: 665 QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAE-AGNSSIQE------GKEEPQNYT 717 KP P T + T + T + A + ++++E K P+ Sbjct: 610 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 669 Query: 718 DSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIK 777 +++ S+ S + + A E +PT + + ++ T Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKETAP--------TTPKEPAPTTPKKPAPTTPETPPPTTS 721 Query: 778 ALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAE-YI 836 + T + P + T +LS P + +SP+ P + ++ + + Sbjct: 722 EVSTPTTTKEPTTIHKSPDESTPELSAEPTP----KALENSPKEPGVPTTKTPAATKPEM 777 Query: 837 TTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQ-TATQTSVVVKSIPASSPG 895 TT D+ TE + + ++ T + +S+ TAT T V + ++P Sbjct: 778 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 837 Query: 896 AITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLS 955 IT + L+ TK + + T E + +T P+ R+ +++ + K QK + Sbjct: 838 KITTLKTTTLAPKVTTTK--KTITTTEIMNKPEETAKPKD----RATNSKATTPKPQKPT 891 Query: 956 QPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPK 1015 + P + T TK+ +T MP+ +R K TP ++ Sbjct: 892 KAPKKPT----------STKKPKT--------------MPR--VRKPKTTPTPRKMTSTM 925 Query: 1016 PDVQHT 1021 P++ T Sbjct: 926 PELNPT 931 Score = 66.2 bits (160), Expect = 2e-10 Identities = 141/699 (20%), Positives = 228/699 (32%), Gaps = 76/699 (10%) Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPS---GSIATVKSPRPASPASNVVVLPSGSTVYV 189 PA T +KE + T T P P+ + T K P P +P P Sbjct: 262 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK------ 315 Query: 190 KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249 E + T ++ P + P P T P +P + A Sbjct: 316 -------EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPA 365 Query: 250 NSLPPHMSPVKITFTKPST--QTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P P+T + TTT+ T P+ T + + + T Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 425 Query: 308 PTSVI----ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVV 363 P A TT K P T + + + + ++T P P T A +TP Sbjct: 426 PAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPA--PTTPKET 482 Query: 364 MSTVAQGVS-TSAIKMASTRLPSPKSLVS---APTQILAQFPKQHQQSPKQQLYQVQQQT 419 T + ++ T+ K+A T P APT P ++ T Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 542 Query: 420 QQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQ---VQPSKILPKPVTAT 476 ++ A +P + P P K T + ++ P K PK + Sbjct: 543 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-- 600 Query: 477 LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536 PT++ P A TTP GT T + + A T T T Sbjct: 601 -PTTTKEPTSTTCDKPA------PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 653 Query: 537 GSIITV----VPKSLA--TLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590 T PK LA T G +++ TT T P T K K T Sbjct: 654 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 713 Query: 591 IQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK 650 P + V+T TI P + P + + P K + PK G Sbjct: 714 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL--SAEPTPKALENSPKEPG-------- 763 Query: 651 IIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGK 710 +PT KT KP+ T +E+ + ET A ++ + ++ ++ Sbjct: 764 -VPTT-------KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 815 Query: 711 EEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQ 770 E T + +ST ++QD+ P I + + ++ T TI ++ ++ + Sbjct: 816 ESKITATTTQVTST----TTQDTTP--FKITTLKTTTLAPKVT-TTKKTITTTEIMNKPE 868 Query: 771 SATSTIKALLELQQTTVKEKLESK-PRQPTIDLSQMAVP 808 + TT K + +K P++PT +P Sbjct: 869 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP 907 Score = 60.8 bits (146), Expect = 8e-09 Identities = 125/588 (21%), Positives = 200/588 (34%), Gaps = 64/588 (10%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKP----- 201 T+T S PT+ PS + T K P P +P P ++P Sbjct: 406 TTTKSAPTTPKEPSPT--TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463 Query: 202 RKRRRTNSSSSSPVVLKE----VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS 257 +K T +P KE PK + P + P + + +A + P + Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523 Query: 258 PV---KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS 314 P + T P NT + P+ T + A T T A Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---AP 580 Query: 315 TTQKPPVVIT----ASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS------STPSVVM 364 TT K P T A + + + +S++ P P T TA + +TP Sbjct: 581 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 640 Query: 365 STVAQGVSTSAIK---MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421 T +G + + +K + + P+PK L T+ S K ++ Sbjct: 641 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKETAPT 695 Query: 422 QVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS 481 +P+P + ++ +P P PT S V T +P+ I P +T P S Sbjct: 696 TPKEPAPTTPKKPAPTTPETP--PPT-----TSEVSTPTTTKEPTTIHKSPDEST-PELS 747 Query: 482 NSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541 P N + K PT T+P ++ + T +TT+ + Sbjct: 748 AEPTPKALEN----SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA--P 801 Query: 542 VVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT 601 + K AT K S I + TT +T + P I KTT + T Sbjct: 802 KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 861 Query: 602 TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ 661 ++N K +T + AT P + PK ST +P K +P ++ Sbjct: 862 EIMN----KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP--KTMPRV----RK 911 Query: 662 GKTQVLIKPKPVTFQATVVS-EQTRQLVTETLQQASRVAEAGNSSIQE 708 KT P P +T+ T ++ LQ +R + NS + E Sbjct: 912 PKT----TPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 955 Score = 60.1 bits (144), Expect = 1e-08 Identities = 61/308 (19%), Positives = 121/308 (39%), Gaps = 26/308 (8%) Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPSG----SIATVKSPRPASPASNVVVLPSGSTVY 188 P + KE+ + TST + P P+ + T K P P +P P Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 719 Query: 189 VKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAV--------VPVSKTITVPVSGSPK 240 VS ++P ++ S+ + + PKA+ VP +KT P + P+ Sbjct: 720 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT---PAATKPE 776 Query: 241 MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300 M+ + +P T T+ T TTT+K + ++T V + ++ Sbjct: 777 MTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 836 Query: 301 AAVTKLVPTSVIASTTQKPPVVITA------SQSSLVSNSSSGSSSSTPSPIPNTVAVTA 354 +T L T++ T + T +++ + ++ S ++TP P T A Sbjct: 837 FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 896 Query: 355 VVSSTPSVVMSTVAQGVSTSAIKMASTRLP--SPKSLVSAPTQILAQFPKQHQQSPKQQL 412 S+ M V + +T + ++ +P +P S ++ + + Q + Q+P +L Sbjct: 897 PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIA---EAMLQTTTRPNQTPNSKL 953 Query: 413 YQVQQQTQ 420 +V +++ Sbjct: 954 VEVNPKSE 961 Score = 53.1 bits (126), Expect = 2e-06 Identities = 94/456 (20%), Positives = 146/456 (32%), Gaps = 69/456 (15%) Query: 101 PLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAE---TGSKEVVCYSYTSTTSTPTSTP 157 P P+ T TA P P E T +KE TSTT + Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP-----TSTTCDKPAPT 618 Query: 158 VPSGSIATV-KSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPV- 215 P G+ T K P P +P P G+ +KP + +++ P Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 678 Query: 216 VLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTT 275 + P P T P +P PP P + P+T TT Sbjct: 679 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP---PTTSEVSTPTTTKEPTTI 735 Query: 276 QKVIIVTTSP-SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334 K +T S+ P L S V PT+ + T KP + TA + + Sbjct: 736 HKSPDESTPELSAEPTPKALENSPKEPGV----PTTKTPAAT-KPEMTTTAKDKTTERDL 790 Query: 335 SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPT 394 + ++T +P T +T S + +T Q ST+ ++ + K+ AP Sbjct: 791 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 850 Query: 395 QILAQ---FPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451 + + P++ + T + P P Q+P ++P P Sbjct: 851 VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP----QKPTKAPKKP--------- 897 Query: 452 QESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYT 511 T +P K +P+ K TTPT + T T Sbjct: 898 --------TSTKKP-KTMPR------------------------VRKPKTTPTPRKMTST 924 Query: 512 RPTVSPSIGRMAATPGAATYVKTTSGS-IITVVPKS 546 P ++P+ A T T S ++ V PKS Sbjct: 925 MPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 960 Score = 48.9 bits (115), Expect = 3e-05 Identities = 170/908 (18%), Positives = 283/908 (31%), Gaps = 117/908 (12%) Query: 281 VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340 VTT +ST N +S S K+ I PP T+ ++SL N + Sbjct: 99 VTTPDTSTTQHNKVSTS------PKITTAKPINPRPSLPPNSDTSKETSLTVNKET---- 148 Query: 341 STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQF 400 V ++T + ST + +TSA + S S K L + Sbjct: 149 ----------TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 198 Query: 401 PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK--PTIQIKQESGVKI 458 PK + L ++ T +P+ + ++ P P IK PT K+ + Sbjct: 199 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKE-----PTPTTIKSAPTTP-KEPAPTTT 252 Query: 459 ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPS 518 + P + P PT+ P + A TTK T A T +P+ Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312 Query: 519 IGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNV 578 + A TT PK A T T P P Sbjct: 313 TPKEPA--------PTTPKEPTPTTPKEPAPT------------TKEPAPTTPKEPAPTA 352 Query: 579 IVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRP---ITKMIV 635 T P + TT + PT K A T P TK Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412 Query: 636 TQPK--GIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQ 693 T PK +T +PA PT ++ KP P T + + T T + Sbjct: 413 TTPKEPSPTTTKEPA----PTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465 Query: 694 QASRVAE--AGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHE 751 A + A + + P+ T ++ + + + +A + Sbjct: 466 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 525 Query: 752 IAMETSPTIIYQDV-SSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQ 810 E +PT ++ + A +T K E TT KE + P++ + P Sbjct: 526 TPEEPAPTTPKAAAPNTPKEPAPTTPK---EPAPTTPKEPAPTTPKETAPTTPKGTAPTT 582 Query: 811 MTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLL 870 + + +P+ P+ + +A T E T + P + P P +P T Sbjct: 583 LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPAPTTP 636 Query: 871 QHVA-QSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMD 929 + A + T + + + P + + + T + T E Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 696 Query: 930 TLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQH 989 +P + A T ++ PP +++ T TK+ TIH D+ Sbjct: 697 PKEPAPTTPKKPAPTTPET--------PPPTTSEVSTPT----TTKEPTTIHKSPDESTP 744 Query: 990 KLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAV 1049 +L P TP E + +P V T+ P K T Sbjct: 745 ELSAEP---------TPKALENSPKEPGVPTTKTPAATKPEMTTTAKD------------ 783 Query: 1050 KTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFE 1109 KTT++ + P+T + + + T E I + VT T + Sbjct: 784 KTTER-----------DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832 Query: 1110 GRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVD 1169 P +T + + PK+T+ +I+ + K + K ++ T Sbjct: 833 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 892 Query: 1170 PPKKALAT 1177 PKK +T Sbjct: 893 APKKPTST 900 Score = 40.4 bits (93), Expect = 0.011 Identities = 181/968 (18%), Positives = 296/968 (30%), Gaps = 116/968 (11%) Query: 345 PIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404 P P V S + ST+ ST SPK + P P Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST---SPKITTAKPINPRPSLPPNS 134 Query: 405 QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQ 464 S + L V ++T + + + + Q K T I++ S + Sbjct: 135 DTSKETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL----AP 189 Query: 465 PSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAA 524 SK+L KP +P ++ G +TT TPT + + P+ + + Sbjct: 190 TSKVLAKP----------TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 239 Query: 525 TPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKT 584 P T+ PK A TTTK P T K K Sbjct: 240 APTTPKEPAPTTTKSAPTTPKEPAP-------------TTTK-EPAPTTPKEPAPTTTKE 285 Query: 585 TGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK-PAILTATRPITKMIVTQPKGIGS 643 TT K+ TT + PT K PA T P T PK Sbjct: 286 PAPTTT------KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP----TTPKEPAP 335 Query: 644 TVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRV----A 699 T + A P ++ KP P T + + T T + + A Sbjct: 336 TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389 Query: 700 EAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIA----ME 755 S +EP T S+ +T S ++ + + A E Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449 Query: 756 TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEK 815 +PT + + ++ T E TT KE + P++ T + P Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTPK--EPAPTTPKETAPTTPKKLTPTTPEKLAPT------ 501 Query: 816 RHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQ 875 +PE P A E +A E T E P + P P +P T + A Sbjct: 502 --TPEKP--APTTPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAP 556 Query: 876 SQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELG---TEEGEVEEMDTLD 932 + K ++P + + T +EL T+E D Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 616 Query: 933 PQTGLFYRSALTQSQSAKQQKLSQP-------------PLEQTQLQVKTLQCFQTKQKQT 979 P T + + K P P T + + T K Sbjct: 617 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676 Query: 980 IHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQP 1039 +D+ P P+ + P +P P T P + + PT +P Sbjct: 677 TSTTSDK---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS-EVSTPTTTKEP 732 Query: 1040 PQTVVQVLAVKTTQQL---PKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPI 1096 T + ++T +L P + N PK P T + P + E+ + Sbjct: 733 --TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 790 Query: 1097 ITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLME 1156 T + T ++ T T+ T S + T+ VTS + + + LK + + Sbjct: 791 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT--LKTTTLA 848 Query: 1157 AQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPST 1216 ++ T KK + T+ + + +TP+ QK ++ P++ Sbjct: 849 PKVTTT---------KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 899 Query: 1217 VGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVE 1276 T ++ P T + M E +P I +A+ Q + + N Sbjct: 900 TKKPKTMPRVRKPKTTPTPRKMT-----STMPELNPTSRIAEAMLQTTTRPNQTPN---- 950 Query: 1277 PSGLLELN 1284 S L+E+N Sbjct: 951 -SKLVEVN 957 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 73.6 bits (179), Expect = 1e-12 Identities = 171/906 (18%), Positives = 313/906 (34%), Gaps = 109/906 (12%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASN------VVVLPSGSTVYVKSVSCSDEDEK 200 TSTT + P + A +PRP+ P ++ + + +TV K + +++ Sbjct: 145 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 204 Query: 201 PRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVK 260 + +T S+ + + K K + P SK + P +PK + A + P +P Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP---TPKAETTTKGPALTTPKEPTPT- 260 Query: 261 ITFTKPSTQT----TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316 T +P++ T T TT + P+ T + + A T P A TT Sbjct: 261 -TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP----APTT 315 Query: 317 QKPPVVITASQSSLVSNSSSGSSSSTPSP-IPNTVAVTAVVSSTPSVVMSTVAQGVSTSA 375 K P T + + + S+ ++ P+P P A T P+ +T Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP---TTPK 372 Query: 376 IKMASTRLPSP----KSLVSAPTQILAQFPKQ-HQQSPKQQL-YQVQQQTQQQVAQPSPV 429 +T+ P+P + +AP + PK+ +PK+ ++ + +P+P Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 432 Query: 430 SHQQQP--QQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT--ATLPTSSNSPI 485 + + P + P P K +E + + P P T PT+ P Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492 Query: 486 MVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545 A TTK T + T P + TP TT + P+ Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP-------TTPEKLAPTTPE 545 Query: 546 SLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLN 605 A + ++ T P + P T P Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605 Query: 606 AGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK-IIPTKIVYGQQGKT 664 ++T T P G P L P T PK +PA K + PT ++ + Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAP------TTPK------KPAPKELAPTTT---KEPTS 650 Query: 665 QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAE-AGNSSIQE------GKEEPQNYT 717 KP P T + T + T + A + ++++E K P+ Sbjct: 651 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 710 Query: 718 DSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIK 777 +++ S+ S + + A E +PT + + ++ T Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKETAP--------TTPKEPAPTTPKKPAPTTPETPPPTTS 762 Query: 778 ALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAE-YI 836 + T + P + T +LS P + +SP+ P + ++ + + Sbjct: 763 EVSTPTTTKEPTTIHKSPDESTPELSAEPTP----KALENSPKEPGVPTTKTPAATKPEM 818 Query: 837 TTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQ-TATQTSVVVKSIPASSPG 895 TT D+ TE + + ++ T + +S+ TAT T V + ++P Sbjct: 819 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 878 Query: 896 AITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLS 955 IT + L+ TK + + T E + +T P+ R+ +++ + K QK + Sbjct: 879 KITTLKTTTLAPKVTTTK--KTITTTEIMNKPEETAKPKD----RATNSKATTPKPQKPT 932 Query: 956 QPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPK 1015 + P + T TK+ +T MP+ +R K TP ++ Sbjct: 933 KAPKKPT----------STKKPKT--------------MPR--VRKPKTTPTPRKMTSTM 966 Query: 1016 PDVQHT 1021 P++ T Sbjct: 967 PELNPT 972 Score = 66.2 bits (160), Expect = 2e-10 Identities = 141/699 (20%), Positives = 228/699 (32%), Gaps = 76/699 (10%) Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPS---GSIATVKSPRPASPASNVVVLPSGSTVYV 189 PA T +KE + T T P P+ + T K P P +P P Sbjct: 303 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK------ 356 Query: 190 KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249 E + T ++ P + P P T P +P + A Sbjct: 357 -------EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPA 406 Query: 250 NSLPPHMSPVKITFTKPST--QTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307 + P +P P+T + TTT+ T P+ T + + + T Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 466 Query: 308 PTSVI----ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVV 363 P A TT K P T + + + + ++T P P T A +TP Sbjct: 467 PAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPA--PTTPKET 523 Query: 364 MSTVAQGVS-TSAIKMASTRLPSPKSLVS---APTQILAQFPKQHQQSPKQQLYQVQQQT 419 T + ++ T+ K+A T P APT P ++ T Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 583 Query: 420 QQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQ---VQPSKILPKPVTAT 476 ++ A +P + P P K T + ++ P K PK + Sbjct: 584 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-- 641 Query: 477 LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536 PT++ P A TTP GT T + + A T T T Sbjct: 642 -PTTTKEPTSTTCDKPA------PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 694 Query: 537 GSIITV----VPKSLA--TLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590 T PK LA T G +++ TT T P T K K T Sbjct: 695 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 754 Query: 591 IQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK 650 P + V+T TI P + P + + P K + PK G Sbjct: 755 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL--SAEPTPKALENSPKEPG-------- 804 Query: 651 IIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGK 710 +PT KT KP+ T +E+ + ET A ++ + ++ ++ Sbjct: 805 -VPTT-------KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 856 Query: 711 EEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQ 770 E T + +ST ++QD+ P I + + ++ T TI ++ ++ + Sbjct: 857 ESKITATTTQVTST----TTQDTTP--FKITTLKTTTLAPKVT-TTKKTITTTEIMNKPE 909 Query: 771 SATSTIKALLELQQTTVKEKLESK-PRQPTIDLSQMAVP 808 + TT K + +K P++PT +P Sbjct: 910 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP 948 Score = 60.8 bits (146), Expect = 8e-09 Identities = 125/588 (21%), Positives = 200/588 (34%), Gaps = 64/588 (10%) Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKP----- 201 T+T S PT+ PS + T K P P +P P ++P Sbjct: 447 TTTKSAPTTPKEPSPT--TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504 Query: 202 RKRRRTNSSSSSPVVLKE----VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS 257 +K T +P KE PK + P + P + + +A + P + Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564 Query: 258 PV---KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS 314 P + T P NT + P+ T + A T T A Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---AP 621 Query: 315 TTQKPPVVIT----ASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS------STPSVVM 364 TT K P T A + + + +S++ P P T TA + +TP Sbjct: 622 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 681 Query: 365 STVAQGVSTSAIK---MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421 T +G + + +K + + P+PK L T+ S K ++ Sbjct: 682 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKETAPT 736 Query: 422 QVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS 481 +P+P + ++ +P P PT S V T +P+ I P +T P S Sbjct: 737 TPKEPAPTTPKKPAPTTPETP--PPT-----TSEVSTPTTTKEPTTIHKSPDEST-PELS 788 Query: 482 NSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541 P N + K PT T+P ++ + T +TT+ + Sbjct: 789 AEPTPKALEN----SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA--P 842 Query: 542 VVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT 601 + K AT K S I + TT +T + P I KTT + T Sbjct: 843 KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 902 Query: 602 TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ 661 ++N K +T + AT P + PK ST +P K +P ++ Sbjct: 903 EIMN----KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP--KTMPRV----RK 952 Query: 662 GKTQVLIKPKPVTFQATVVS-EQTRQLVTETLQQASRVAEAGNSSIQE 708 KT P P +T+ T ++ LQ +R + NS + E Sbjct: 953 PKT----TPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 996 Score = 60.1 bits (144), Expect = 1e-08 Identities = 61/308 (19%), Positives = 121/308 (39%), Gaps = 26/308 (8%) Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPSG----SIATVKSPRPASPASNVVVLPSGSTVY 188 P + KE+ + TST + P P+ + T K P P +P P Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 760 Query: 189 VKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAV--------VPVSKTITVPVSGSPK 240 VS ++P ++ S+ + + PKA+ VP +KT P + P+ Sbjct: 761 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT---PAATKPE 817 Query: 241 MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300 M+ + +P T T+ T TTT+K + ++T V + ++ Sbjct: 818 MTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 877 Query: 301 AAVTKLVPTSVIASTTQKPPVVITA------SQSSLVSNSSSGSSSSTPSPIPNTVAVTA 354 +T L T++ T + T +++ + ++ S ++TP P T A Sbjct: 878 FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 937 Query: 355 VVSSTPSVVMSTVAQGVSTSAIKMASTRLP--SPKSLVSAPTQILAQFPKQHQQSPKQQL 412 S+ M V + +T + ++ +P +P S ++ + + Q + Q+P +L Sbjct: 938 PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIA---EAMLQTTTRPNQTPNSKL 994 Query: 413 YQVQQQTQ 420 +V +++ Sbjct: 995 VEVNPKSE 1002 Score = 53.1 bits (126), Expect = 2e-06 Identities = 94/456 (20%), Positives = 146/456 (32%), Gaps = 69/456 (15%) Query: 101 PLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAE---TGSKEVVCYSYTSTTSTPTSTP 157 P P+ T TA P P E T +KE TSTT + Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP-----TSTTCDKPAPT 659 Query: 158 VPSGSIATV-KSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPV- 215 P G+ T K P P +P P G+ +KP + +++ P Sbjct: 660 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 719 Query: 216 VLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTT 275 + P P T P +P PP P + P+T TT Sbjct: 720 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP---PTTSEVSTPTTTKEPTTI 776 Query: 276 QKVIIVTTSP-SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334 K +T S+ P L S V PT+ + T KP + TA + + Sbjct: 777 HKSPDESTPELSAEPTPKALENSPKEPGV----PTTKTPAAT-KPEMTTTAKDKTTERDL 831 Query: 335 SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPT 394 + ++T +P T +T S + +T Q ST+ ++ + K+ AP Sbjct: 832 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 891 Query: 395 QILAQ---FPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451 + + P++ + T + P P Q+P ++P P Sbjct: 892 VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP----QKPTKAPKKP--------- 938 Query: 452 QESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYT 511 T +P K +P+ K TTPT + T T Sbjct: 939 --------TSTKKP-KTMPR------------------------VRKPKTTPTPRKMTST 965 Query: 512 RPTVSPSIGRMAATPGAATYVKTTSGS-IITVVPKS 546 P ++P+ A T T S ++ V PKS Sbjct: 966 MPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1001 Score = 48.9 bits (115), Expect = 3e-05 Identities = 170/908 (18%), Positives = 283/908 (31%), Gaps = 117/908 (12%) Query: 281 VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340 VTT +ST N +S S K+ I PP T+ ++SL N + Sbjct: 140 VTTPDTSTTQHNKVSTS------PKITTAKPINPRPSLPPNSDTSKETSLTVNKET---- 189 Query: 341 STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQF 400 V ++T + ST + +TSA + S S K L + Sbjct: 190 ----------TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 239 Query: 401 PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK--PTIQIKQESGVKI 458 PK + L ++ T +P+ + ++ P P IK PT K+ + Sbjct: 240 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKE-----PTPTTIKSAPTTP-KEPAPTTT 293 Query: 459 ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPS 518 + P + P PT+ P + A TTK T A T +P+ Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353 Query: 519 IGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNV 578 + A TT PK A T T P P Sbjct: 354 TPKEPA--------PTTPKEPTPTTPKEPAPT------------TKEPAPTTPKEPAPTA 393 Query: 579 IVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRP---ITKMIV 635 T P + TT + PT K A T P TK Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453 Query: 636 TQPK--GIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQ 693 T PK +T +PA PT ++ KP P T + + T T + Sbjct: 454 TTPKEPSPTTTKEPA----PTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506 Query: 694 QASRVAE--AGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHE 751 A + A + + P+ T ++ + + + +A + Sbjct: 507 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 566 Query: 752 IAMETSPTIIYQDV-SSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQ 810 E +PT ++ + A +T K E TT KE + P++ + P Sbjct: 567 TPEEPAPTTPKAAAPNTPKEPAPTTPK---EPAPTTPKEPAPTTPKETAPTTPKGTAPTT 623 Query: 811 MTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLL 870 + + +P+ P+ + +A T E T + P + P P +P T Sbjct: 624 LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPAPTTP 677 Query: 871 QHVA-QSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMD 929 + A + T + + + P + + + T + T E Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 737 Query: 930 TLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQH 989 +P + A T ++ PP +++ T TK+ TIH D+ Sbjct: 738 PKEPAPTTPKKPAPTTPET--------PPPTTSEVSTPT----TTKEPTTIHKSPDESTP 785 Query: 990 KLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAV 1049 +L P TP E + +P V T+ P K T Sbjct: 786 ELSAEP---------TPKALENSPKEPGVPTTKTPAATKPEMTTTAKD------------ 824 Query: 1050 KTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFE 1109 KTT++ + P+T + + + T E I + VT T + Sbjct: 825 KTTER-----------DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873 Query: 1110 GRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVD 1169 P +T + + PK+T+ +I+ + K + K ++ T Sbjct: 874 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 933 Query: 1170 PPKKALAT 1177 PKK +T Sbjct: 934 APKKPTST 941 Score = 40.4 bits (93), Expect = 0.011 Identities = 181/968 (18%), Positives = 296/968 (30%), Gaps = 116/968 (11%) Query: 345 PIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404 P P V S + ST+ ST SPK + P P Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST---SPKITTAKPINPRPSLPPNS 175 Query: 405 QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQ 464 S + L V ++T + + + + Q K T I++ S + Sbjct: 176 DTSKETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL----AP 230 Query: 465 PSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAA 524 SK+L KP +P ++ G +TT TPT + + P+ + + Sbjct: 231 TSKVLAKP----------TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 280 Query: 525 TPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKT 584 P T+ PK A TTTK P T K K Sbjct: 281 APTTPKEPAPTTTKSAPTTPKEPAP-------------TTTK-EPAPTTPKEPAPTTTKE 326 Query: 585 TGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK-PAILTATRPITKMIVTQPKGIGS 643 TT K+ TT + PT K PA T P T PK Sbjct: 327 PAPTTT------KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP----TTPKEPAP 376 Query: 644 TVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRV----A 699 T + A P ++ KP P T + + T T + + A Sbjct: 377 TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430 Query: 700 EAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIA----ME 755 S +EP T S+ +T S ++ + + A E Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490 Query: 756 TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEK 815 +PT + + ++ T E TT KE + P++ T + P Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTPK--EPAPTTPKETAPTTPKKLTPTTPEKLAPT------ 542 Query: 816 RHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQ 875 +PE P A E +A E T E P + P P +P T + A Sbjct: 543 --TPEKP--APTTPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAP 597 Query: 876 SQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELG---TEEGEVEEMDTLD 932 + K ++P + + T +EL T+E D Sbjct: 598 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 657 Query: 933 PQTGLFYRSALTQSQSAKQQKLSQP-------------PLEQTQLQVKTLQCFQTKQKQT 979 P T + + K P P T + + T K Sbjct: 658 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717 Query: 980 IHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQP 1039 +D+ P P+ + P +P P T P + + PT +P Sbjct: 718 TSTTSDK---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS-EVSTPTTTKEP 773 Query: 1040 PQTVVQVLAVKTTQQL---PKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPI 1096 T + ++T +L P + N PK P T + P + E+ + Sbjct: 774 --TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 831 Query: 1097 ITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLME 1156 T + T ++ T T+ T S + T+ VTS + + + LK + + Sbjct: 832 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT--LKTTTLA 889 Query: 1157 AQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPST 1216 ++ T KK + T+ + + +TP+ QK ++ P++ Sbjct: 890 PKVTTT---------KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 940 Query: 1217 VGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVE 1276 T ++ P T + M E +P I +A+ Q + + N Sbjct: 941 TKKPKTMPRVRKPKTTPTPRKMT-----STMPELNPTSRIAEAMLQTTTRPNQTPN---- 991 Query: 1277 PSGLLELN 1284 S L+E+N Sbjct: 992 -SKLVEVN 998 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 70.5 bits (171), Expect = 1e-11 Identities = 269/1257 (21%), Positives = 418/1257 (33%), Gaps = 192/1257 (15%) Query: 85 GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCY 144 GP S++ S G L+P N A+ ++ AS PV + TGS Sbjct: 1772 GPESTTFHSSPGSTETTLLPD-----------NTTASGLLE--ASTPVHSSTGSPHTTLS 1818 Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPS---GSTVYVKSVSCSDEDEKP 201 STT ST S + P P + S V L + GS + S Sbjct: 1819 PAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 1878 Query: 202 RKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGS---------------PKMSNIMQ 246 + + + SSPV P P T + V S P+ S Sbjct: 1879 GRSEESTTVHSSPVATATTPS---PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASG 1935 Query: 247 SIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNI------------- 293 S H S + PS TT+ ++ +SP ST + Sbjct: 1936 RSEESRTSHSSTTHTISSPPS--TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 1993 Query: 294 -LSKSHNYAAVTKLVP----TSVIASTTQKPPVVITASQSSLVSNSSS----GSSSSTPS 344 S S A T ++P TSV+ + P+ + +++ + S++ S+T Sbjct: 1994 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH 2053 Query: 345 PIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404 P + A T +ST S S V++ +TS + ST + + P Sbjct: 2054 SSPRSPATTLSPASTTS---SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 2110 Query: 405 QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQ-PQQSPLPPGIKPTIQIKQESGVKIITQQV 463 T +Q S SH + L PG + QES + Sbjct: 2111 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS 2170 Query: 464 QPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTG-----------TQATYTR 512 + + P T++ +++ V SS G+ TT + T T T Sbjct: 2171 THTTLFPDSTTSSGIVEAST--RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 2228 Query: 513 PTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLG----GKIISSNIVSGTTTKIT 568 T SP A + TY ++ + T P S T G I S+ + TT + Sbjct: 2229 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2288 Query: 569 TIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE--KTIQTVPTGAKPAILTA 626 TS + + T I LPG L A + ++ T PA +T+ Sbjct: 2289 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTS 2348 Query: 627 TRPITKMIV--TQPKGIGSTVQPAAKIIP------TKIVYGQQGKTQVLIKPK------- 671 + +QP STV PA+ P T + G T+ + P+ Sbjct: 2349 LGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVR 2408 Query: 672 ---PVTFQATVVSEQ----TRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724 P TF + S T T L + S +S Q G D ST Sbjct: 2409 GEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEEST 2468 Query: 725 ESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ 784 SS + + S + + E++P+ + S S + T+T+ Sbjct: 2469 TFPSSSGSTGTTLSPARS-----TTSGLVGESTPSRL-----SPSSTETTTL-------- 2510 Query: 785 TTVKEKLESKPRQPTI-DLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDE 843 P PT LS+ + + + SP A S V+E +T + Sbjct: 2511 ----------PGSPTTPSLSEKSTTFYTSPRSPDATLSP--ATTTSSGVSEESSTSHSQP 2558 Query: 844 GT--EVAFP-------LLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPAS-- 892 G+ AFP L + P TLL + +Q S S P S Sbjct: 2559 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 2618 Query: 893 ---SPGAITHIM--QQALSSHTA----FTKHSEELGTEEGEVEEMDTLDPQTGLFYRSAL 943 SPG+ T + Q++ + H++ T + T G VE + TG R+ L Sbjct: 2619 TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTL 2677 Query: 944 TQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLP-QMPQLSIRHQ 1002 + + S + QT T T ++ H+ P P Sbjct: 2678 SPASSTSPGLQGESTTFQTH-PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 2736 Query: 1003 KLTPLQQEQA---QPKPDVQHT----QHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQL 1055 T E++ PD T H + + T P T + L TT Sbjct: 2737 STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT--T 2794 Query: 1056 PKLQQAPNQPKIYVQPQTPQSQMSLPAS------SEKQTASQVEQPIITQGSSVTKITFE 1109 P L +A Y P++P + +S PAS E+ T S+ QP GS+ + ++ Sbjct: 2795 PGLSEA--STTFYSSPRSPTTTLS-PASMTSLGVGEESTTSR-SQP----GSTHSTVSPA 2846 Query: 1110 GRQPPTVTK--ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMI 1167 P +++ T SS P T T++ P S T+V + T+ Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTE--TTVFP--RSTTTSVRGEEPTTFHSRPASTHTTLFT 2902 Query: 1168 VDPPKKALATSMLTGEAGSLP-STHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223 D TS LT E+ + P S G+ + ES + PS+ GS+ TT Sbjct: 2903 EDS-----TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT 2954 Score = 65.1 bits (157), Expect = 4e-10 Identities = 268/1277 (20%), Positives = 432/1277 (33%), Gaps = 151/1277 (11%) Query: 128 ASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTV 187 AS PV + TGS +STT T S + SP P+ S V L ST Sbjct: 391 ASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKL---STT 447 Query: 188 YVKSVSCSDEDEKPRKRRRTNSSSSSPVV---LKEVPKAVVPVSKTITVPVSGSPKMSNI 244 Y S P T+ S+SS + + P PV+ T P + S ++ Sbjct: 448 YHSS---------PSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHV 498 Query: 245 MQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNIL-SKSHNYAAV 303 +S A H SP STQT + + S+TF + +KS + Sbjct: 499 EESTAY----HRSP-------GSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTT 547 Query: 304 TKLVPTSVIAS-----TT--QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356 L TS +S TT + + S+ S S+SS + ++T P +T +V V Sbjct: 548 AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSV-LVG 606 Query: 357 SSTPSVVM-----------STVAQGVS-TSAIKMASTRLPSPKSLVSAPTQ--ILAQFPK 402 STPS + ST G+S S +S R P L ++ T + + Sbjct: 607 DSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTT 666 Query: 403 QHQQSPKQQLYQVQ-QQTQQQVAQPSPVSHQQQ-PQQSPLPPGIKPTIQIKQESGVKIIT 460 H + T ++Q S SH P + L PG + E Sbjct: 667 SHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSR 726 Query: 461 QQVQPSKILPKPVTAT--------LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATY-T 511 + +LP TA+ + +S+ SP +S G+ TT G T+ + Sbjct: 727 PGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGS-------TTRQGESTTFHS 779 Query: 512 RPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIP 571 P+ + T A TTS + +P + + + +S +V +TT ++ Sbjct: 780 WPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT--HISARSTTSGLVEESTTYHSSPG 837 Query: 572 MTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTV--PTG--AKPAILTAT 627 T + T+G+G + + T +++ T V PT + P TAT Sbjct: 838 STQTMHFPESDTTSGRGE--ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG-STAT 894 Query: 628 RPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL 687 T + ST +++ IV + T VL+ ++T + + Sbjct: 895 THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG------ESTTSPISSGSM 948 Query: 688 VTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDW 747 T L ++ S T S +ST SS S++S SR + Sbjct: 949 ETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEES------TTSRSRPG 1002 Query: 748 SEHEIAMETSPTI--IYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQM 805 S H A S T + + ++ S ST LL TT ES + + Sbjct: 1003 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDT 1062 Query: 806 AVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQP 865 A+ T ES + T G A + S P+ P Sbjct: 1063 ALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 1122 Query: 866 QRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH----TAFTKHSEELGTE 921 + + TA QT S P T ++++ + H + T H T Sbjct: 1123 ASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT 1182 Query: 922 EGEVEE---MDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQ 978 G E+ + +G SA + + + S+ + ++ TL T Sbjct: 1183 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR--ISPGSTEITTLPGSTTTPGL 1240 Query: 979 TIHLQADQLQHKLPQMPQLSIRHQKLTPL-QQEQAQPKPDVQHTQHPMVAKDRQLPTLMA 1037 + +A + P+ P ++ +T L E++ + H V+ P Sbjct: 1241 S---EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS-----PASTT 1292 Query: 1038 QPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPAS------SEKQTASQ 1091 P + +++ + P+ V + P + S PAS +E T S Sbjct: 1293 TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSG 1352 Query: 1092 VEQ--------PIITQ-GSSVTKITFEGRQPPTVTKITGGSSVPKLT------------S 1130 + + P TQ G T T + + T + GS+ KL+ S Sbjct: 1353 LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGES 1412 Query: 1131 PVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPP-KKALATSMLTGEAGSLP- 1188 + +SP T SL E D A TS E S Sbjct: 1413 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH 1472 Query: 1189 ----STHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRI--QN 1242 STH +ST +E +S S+ GS+ T + GQ + Sbjct: 1473 SQPGSTH--TTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSS 1530 Query: 1243 VGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDI 1302 G + P + I + + + P HSS+ + L + TS L +E T + Sbjct: 1531 PGDTETTLLPDDTITSGLVEASTPTHSSTGSL---HTTLTPASSTSAGLQEESTTFQSWP 1587 Query: 1303 DSSTEDGTEPSPSQSSA 1319 SS T PSP ++A Sbjct: 1588 SSS---DTTPSPPGTTA 1601 Score = 64.7 bits (156), Expect = 6e-10 Identities = 267/1364 (19%), Positives = 450/1364 (32%), Gaps = 222/1364 (16%) Query: 81 HNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAF---TVTANAVANAAIQHNASLPVPAETG 137 H P S++ +E P P T F + T+ + I H++ P +G Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS----PDASG 2757 Query: 138 SKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDE 197 + +S TS T++ + GS + + LP +T S + + Sbjct: 2758 TTPSSAHSTTSGRGESTTSRISPGS-------------TEITTLPGSTTTPGLSEASTTF 2804 Query: 198 DEKPRKRRRTNSSSSSP---VVLKEVPKAVVPVS--KTITVPVSGSPKMSNIMQSIANSL 252 PR T S +S V + P S T++ + +P +S ++ +S Sbjct: 2805 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2864 Query: 253 PPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK---LVPT 309 P T P + TT+ ++ + P+ST + ++ + +T+ P Sbjct: 2865 PGSTE----TTVFPRSTTTSVRGEEPTTFHSRPASTHT-TLFTEDSTTSGLTEESTAFPG 2919 Query: 310 SVIASTTQKPPVVITAS--QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS----TPSVV 363 S ++ T P + TA + S SSSGS+ +T SP +T + S+ +PS Sbjct: 2920 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2979 Query: 364 MSTVAQGVST--SAIKMASTRLPSPKS-------LVSAPTQILAQFPKQHQQSPKQQLYQ 414 +T G T S + ++T SP+S + + + + H Q Sbjct: 2980 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 3039 Query: 415 VQQQTQQQ-VAQPSPVSHQQQ-PQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKP 472 T ++Q SH Q ++ L PG + Q+S + + +LP Sbjct: 3040 FPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD 3099 Query: 473 ------VTATLPTSS-----NSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGR 521 V A+ PT S ++ + SS A + + T + ++ T P SP Sbjct: 3100 TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP--SPPGTT 3157 Query: 522 MAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGT-TTKITTIPMTSKPNVIV 580 A + TY S + T S TLG S+ + S T P S +V+V Sbjct: 3158 AAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLV 3217 Query: 581 VQKTTGK----GTTIQGLPGKNVVTTLLNAGGE--KTIQTVPTGAKPAILTATRPITKMI 634 + TT T LPG L + ++ T PA T++ + Sbjct: 3218 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 3277 Query: 635 V--TQPKGIGSTVQPAAKIIP-----TKIVYGQQGKTQVLIK----------PKPVTFQA 677 ++P +T P + +P + + G T + P+ TF + Sbjct: 3278 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 3337 Query: 678 TVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVV 737 S +T L T AS + EA ++ + P + S+T +S Sbjct: 3338 GPGSTETTLLPDNT--TASGLLEA-STPVHSSTGSPHTTLSPAGSTTRQGES-------- 3386 Query: 738 HVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQ 797 + Q W + PT T A +EL T+ S Sbjct: 3387 ----TTFQSWPNSKDTTPAPPT---------------TTSAFVELSTTS----HGSPSST 3423 Query: 798 PTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRS 857 PT S + + ++E SP +A + A T+ +E T Sbjct: 3424 PTTHFSASSTTLGRSEESTTVHSSP-VATATTPSPARSTTSGLVEEST------------ 3470 Query: 858 QPQQPSQPQRTLLQHVAQSQTA-----------TQTSVVVKSIPASSPGAITHIMQQALS 906 S P T H +S T + T+ + S P+++ + S Sbjct: 3471 --TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS 3528 Query: 907 SHTAFTKHSEELGTEEGEVEE---MDTLDPQTGLFYRSALTQSQ----SAKQQKLSQPPL 959 + T H + T G EE + TG A + + + +S + Sbjct: 3529 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 3588 Query: 960 EQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPL----QQEQAQPK 1015 E T L T +++ T H P+ P ++ T + + + Sbjct: 3589 ETTALPGSTTTPGLSEKSTTF--------HSSPRSPATTLSPASTTSSGVSEESTTSHSR 3640 Query: 1016 PDVQHT-----QHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQ 1070 P HT R T + P T +L TT Q++ Sbjct: 3641 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS-GSSQESTTSHSSSGS 3699 Query: 1071 PQTPQSQMSLPASSEKQTASQV-EQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLT 1129 T S S A S Q ++ P T + T T++ + P+ T Sbjct: 3700 TDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 3759 Query: 1130 -SPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALA----TSMLTGEA 1184 SP +S SP E TA Q H PP A A ++ Sbjct: 3760 LSPASSTSPGLQGESTAF-----------QTHPASTHTTPSPPSTATAPVEESTTYHRSP 3808 Query: 1185 GSLPSTHMVVAG----------MANSTPQQQKCRESCSSPSTVG-SSLTTRKIDPPAVPA 1233 GS P+TH + + +S+P S + +T G TT +I P + Sbjct: 3809 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 3868 Query: 1234 TGQFMRIQNVGQKKAEE-------------SPAEIIIQAIPQYAIPCHS---SSNVVVEP 1277 T G +A SPA + + + + S S++ V P Sbjct: 3869 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP 3928 Query: 1278 SGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAER 1321 + + T+ L +E T + STE P + +S R Sbjct: 3929 A------STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRR 3966 Score = 64.3 bits (155), Expect = 7e-10 Identities = 273/1345 (20%), Positives = 467/1345 (34%), Gaps = 198/1345 (14%) Query: 85 GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCY 144 GP S++ S G L+P N A+ ++ AS PV + TGS Sbjct: 3329 GPESTTFHSGPGSTETTLLPD-----------NTTASGLLE--ASTPVHSSTGSPHTTLS 3375 Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204 STT ST S + +P P + S V L + S P Sbjct: 3376 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTS------------HGSPSST 3423 Query: 205 RRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFT 264 T+ S+SS + + V S + + SP S + S H SP Sbjct: 3424 PTTHFSASSTTLGRSEESTTVH-SSPVATATTPSPARSTTSGLVEESTTYHSSP------ 3476 Query: 265 KPSTQT-----TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS----- 314 STQT ++TT+ + TTS SST + +S + + + PTS +S Sbjct: 3477 -GSTQTMHFPESDTTSGRGEESTTSHSST--THTISSAPSTTSALVEEPTSYHSSPGSTA 3533 Query: 315 TTQKPPVVITA--SQSSLVSNSSSGSSSSTPSPIPNTVAV------TAVVSS----TPSV 362 TT P T+ S+ S S+SS ++ + P +T +V T+ +SS T ++ Sbjct: 3534 TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL 3593 Query: 363 VMSTVAQGVSTSAIKM-ASTRLP----SPKSLVSA------------------------- 392 ST G+S + +S R P SP S S+ Sbjct: 3594 PGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDST 3653 Query: 393 PTQILAQFPKQHQQSP--KQQLYQVQQQTQQQVAQPSPVSHQQQ-PQQSPLPPGIKPTIQ 449 T L++ SP T +Q S SH + L PG + Sbjct: 3654 TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALS 3713 Query: 450 IKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTG---- 505 QES + + + P T++ +++ V SS G+ TT + T Sbjct: 3714 FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAST--RVHSSTGSPRTTLSPASSTSPGLQ 3771 Query: 506 -------TQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLG----GKI 554 T T T SP A + TY ++ + T P S T G I Sbjct: 3772 GESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 3831 Query: 555 ISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE--KTI 612 S+ + TT + TS + + T I LPG L A + Sbjct: 3832 FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP 3891 Query: 613 QTVPTGAKPAILTATRPITKMIV--TQPKGIGSTVQPAAKIIP------TKIVYGQQGKT 664 ++ T PA +T+ + +QP STV PA+ P T + G T Sbjct: 3892 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGST 3951 Query: 665 QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724 + + P+ +T S + + T + AS ++++ T+ S++ Sbjct: 3952 ETTVFPR-----STTTSVRREEPTTFHSRPAST-----HTTLFTEDSTTSGLTEESTAFP 4001 Query: 725 ESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ 784 S S+Q P A ++ + + ++ T + S+ S + + L Sbjct: 4002 GSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS-PS 4060 Query: 785 TTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEG 844 +T L P P+ LS+ + + + SP A S V+E +T + G Sbjct: 4061 STETTTLPGSPTTPS--LSEKSTTFYTSPRSPDATLSP--ATTTSSGVSEESSTSHSQPG 4116 Query: 845 T--EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQ 902 + AFP + Q+P+ SQ +T+ ++ S ASS G Q Sbjct: 4117 STHTTAFPDSTTTSGLSQEPTTSH--------SSQGSTEATLSPGSTTASSLG------Q 4162 Query: 903 QALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQT 962 Q+ + H++ G E + DT+ +GL S T S + P + Sbjct: 4163 QSTTFHSS-------PGDTETTLLPDDTI--TSGLVEASTPTHSSTGSLHTTLTPASSTS 4213 Query: 963 ---QLQVKTLQCFQTKQKQT--------IHLQADQLQHKLPQMPQLSIRHQKLTPL--QQ 1009 Q + T Q + + T + ++ H P + T L + Sbjct: 4214 TGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 4273 Query: 1010 EQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPK--- 1066 E T + L+ +P + + + +TT A K Sbjct: 4274 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 4333 Query: 1067 IYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGS--S 1124 Y P++P + +S PAS+ S+ ++ S+ F P+ T + G S S Sbjct: 4334 FYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPGSMHTTAF-----PSSTTMPGVSQES 4387 Query: 1125 VPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEA 1184 +SP ++ + + TA S + + + + ++ D + T Sbjct: 4388 TASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVH 4447 Query: 1185 GSLPSTHMVVAGMANSTPQQQ--------KCRESCSSPSTVGSS---LTTRKIDPPAVPA 1233 S S H ++ ++T Q + +++ +P T S+ L+T P+ Sbjct: 4448 SSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTP 4507 Query: 1234 TGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDD 1293 T F + E + A P S+++ +VE S + ++Q + Sbjct: 4508 TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHF 4567 Query: 1294 EETAMEQDIDSSTEDGTEPSPSQSS 1318 E+ ++++ G E + S SS Sbjct: 4568 PES------NTTSGRGEESTTSHSS 4586 Score = 62.8 bits (151), Expect = 2e-09 Identities = 152/683 (22%), Positives = 247/683 (36%), Gaps = 106/683 (15%) Query: 85 GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCY 144 GP S++ S G L+P N A+ ++ AS PV + TGS Sbjct: 4412 GPESTTFHSSPGSTETTLLPD-----------NTTASGLLE--ASTPVHSSTGSPHTTLS 4458 Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204 STT ST S + +P P + S V L + S P Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTS------------HGSPSST 4506 Query: 205 RRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFT 264 T+ S+SS + + V S + + SP S + S H SP Sbjct: 4507 PTTHFSASSTTLGRSEESTTVH-SSPVATATTPSPARSTTSGLVEESTTYHSSP------ 4559 Query: 265 KPSTQT-----TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS----- 314 STQT +NTT+ + TTS SST + +S + + + PTS +S Sbjct: 4560 -GSTQTMHFPESNTTSGRGEESTTSHSST--THTISSAPSTTSALVEEPTSYHSSPGSTA 4616 Query: 315 TTQKPPVVITA--SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372 TT P T+ S+ S S+SS ++ + P +T +V S+T S ++ G Sbjct: 4617 TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT-----SPISSGSM 4671 Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432 + ST P + + P H + L + ++ T SPV+ Sbjct: 4672 ETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEEST---TVHSSPVATA 4728 Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT-----LPTSSNSPIMV 487 P P T + +ES + + P+ TA+ TS +S Sbjct: 4729 TTPS-----PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 4783 Query: 488 VSSNGAIMTTKLVTTPT------GTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541 +SS + T+ LV PT G+ AT P S + GR + + + T IT Sbjct: 4784 ISSPPS-TTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNG---IT 4839 Query: 542 VVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT 601 +P T G S+ + TT+ T+ TT PG + + Sbjct: 4840 PLPAHFTTSGRIAESTTFYISPGSMETTLASTA---------TT---------PGLSAKS 4881 Query: 602 TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKII-----PTKI 656 T+L + QT+ + + + P + + +Q + +T PA+ + Sbjct: 4882 TILYSSSRSPDQTLSPASMTSSSISGEPTS--LYSQAESTHTTAFPASTTTSGLSQESTT 4939 Query: 657 VYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQ-EGKEEPQN 715 + + G T+ + P +T S ++ T Q S ++ +S G E Sbjct: 4940 FHSKPGSTETTLSPGSIT-----TSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEEST 4994 Query: 716 YTDSSSSSTESSQSSQDSQPVVH 738 SS STE++ S + +H Sbjct: 4995 TFYSSPGSTETTAFSHSNTMSIH 5017 Score = 60.1 bits (144), Expect = 1e-08 Identities = 261/1326 (19%), Positives = 429/1326 (32%), Gaps = 210/1326 (15%) Query: 73 DERLTTIAHNMSGPN--SSSEWSIEGRRLVPLMPRLVPQTAFTVTANAV-ANAAIQHNAS 129 D L + SGP+ S++ S G L P +F + +N H Sbjct: 1033 DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 1092 Query: 130 LPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYV 189 P + S+T +P +T P+ S T + S A + +T Sbjct: 1093 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS--TSPGLQGESTAFQTHPASTHTTPSP 1150 Query: 190 KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249 S + + +E R S+ P P S T SG + S I S Sbjct: 1151 PSTATAPVEESTTYHRSPGST----------PTTHFPASST----TSGHSEKSTIFHSSP 1196 Query: 250 NSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY-----AAVT 304 ++ S T + TT+ + +TT P ST P + S + + T Sbjct: 1197 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 1256 Query: 305 KLVPTSVIA------STTQK----------PPVVIT----ASQSSLVSNSSSGSSSSTPS 344 L P S+ + STT + P T + +S+ V +SS GS+ +T Sbjct: 1257 TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVF 1316 Query: 345 PIPNTVAV-----TAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPS---------PKSLV 390 P T +V T S S + + +TS + ST P P +L Sbjct: 1317 PHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLT 1376 Query: 391 SAPT-QILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQ 449 +A + FP S +L + T V + +P ++ PG PT Sbjct: 1377 TADLGEESTTFPSS-SGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG-SPTTP 1434 Query: 450 IKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT---------KLV 500 E T P L P T T S S G+ TT L Sbjct: 1435 SLSEKSTTFYTSPRSPDATL-SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLS 1493 Query: 501 TTPTGTQATY--TRPTVSP------SIGRMAAT----PG------------------AAT 530 PT + ++ T T+SP S+G+ + T PG A+T Sbjct: 1494 QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAST 1553 Query: 531 YVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590 +++GS+ T + + +T G S + T P V+ +T + Sbjct: 1554 PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSR 1613 Query: 591 IQGLPGK--NVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIV----TQPKGIGST 644 P + +T L E T GA L TR T ++V T P GST Sbjct: 1614 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 1673 Query: 645 VQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNS 704 A T ++ T P+ + S + + E+ SR + Sbjct: 1674 ETTALPGSTTTAGLSEK-STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTT 1732 Query: 705 SIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQD 764 + P +S++S + + P +S + + + ++ T + D Sbjct: 1733 AFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPD 1792 Query: 765 -------------VSSESQSATSTI----KALLELQQTTVKEKLESKPRQPTIDLSQMAV 807 V S + S +T+ + + TT + SK P + A Sbjct: 1793 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAF 1852 Query: 808 PIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEV-AFPLLVSHRSQPQQP---- 862 ++++ SP S + A T R++E T V + P+ + P + Sbjct: 1853 -VELSTTSHGSPSS----TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 1907 Query: 863 ---------SQPQRTLLQHVAQSQTATQTSVVVKSIPASS-------PGAITHIMQQALS 906 S P T H +S TA+ S ++ +S+ P + ++++ S Sbjct: 1908 LVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTS 1967 Query: 907 SHTA----FTKHSEELGTEEGEVEE---MDTLDPQTGLFYRSALTQSQ----SAKQQKLS 955 H++ T H + T G EE + TG A + + + +S Sbjct: 1968 YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPIS 2027 Query: 956 QPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPL----QQEQ 1011 +E T L T +++ T H P+ P ++ T + Sbjct: 2028 SGSMETTALPGSTTTPGLSEKSTTF--------HSSPRSPATTLSPASTTSSGVSEESTT 2079 Query: 1012 AQPKPDVQHT-----QHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQ--APNQ 1064 + +P HT R T + P T +L TT P + + + Sbjct: 2080 SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2139 Query: 1065 PKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSS 1124 P +P S +L E T P T + T T++ + Sbjct: 2140 PGSTDTALSPGSTTALSFGQESTTFH--SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2197 Query: 1125 VPKLT-SPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALA----TSM 1179 P+ T SP +S SP E TA Q H PP A A ++ Sbjct: 2198 SPRTTLSPASSTSPGLQGESTAF-----------QTHPASTHTTPSPPSTATAPVEESTT 2246 Query: 1180 LTGEAGSLPSTHMVVAG----------MANSTPQQQKCRESCSSPSTVG-SSLTTRKIDP 1228 GS P+TH + + +S+P S + +T G TT +I P Sbjct: 2247 YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 2306 Query: 1229 PAVPAT 1234 + T Sbjct: 2307 GSTEIT 2312 Score = 49.3 bits (116), Expect = 2e-05 Identities = 182/856 (21%), Positives = 285/856 (33%), Gaps = 148/856 (17%) Query: 128 ASLPVPAETGSKEVVCY--SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGS 185 AS P + TGS S TST ST S ++ +P SP S V S Sbjct: 4191 ASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTP---SPPSTTAVPVEVS 4247 Query: 186 TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIM 245 T Y +P T+ S+SS + + V S T Sbjct: 4248 TTY---------HSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT------------- 4285 Query: 246 QSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK 305 +L P S + +P+T ++ + + T P ST + KS + + + Sbjct: 4286 ---GTALFPTRSATSVLVGEPTTSPISSGSTET---TALPGSTTTAGLSEKSTTFYSSPR 4339 Query: 306 LVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSP----IPNTVAVTAVVSSTPS 361 T++ ++T V S+ S S+S GS +T P +P + S+P Sbjct: 4340 SPDTTLSPASTTSSGV----SEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPG 4395 Query: 362 VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421 +T++ G +T AS+ P + S+P S + L Sbjct: 4396 STDTTLSPGSTT-----ASSLGPESTTFHSSP------------GSTETTLLPDNTTASG 4438 Query: 422 QVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSK-ILPKPVTAT---- 476 + +PV + L P T Q G Q SK P P T T Sbjct: 4439 LLEASTPVHSSTGSPHTTLSPAGSTTRQ-----GESTTFQSWPNSKDTTPAPPTTTSAFV 4493 Query: 477 --LPTSSNSPIMVVSSNGAIMTTKL----VTTPTGTQATYTRPTVSPSIGRMAATPGAAT 530 TS SP +++ + +T L +T + T T SP+ + +T Sbjct: 4494 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 4553 Query: 531 YVKTTSGSIITV-VPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGT 589 ++ GS T+ P+S T G S+ S TT I++ P T+ V + T Sbjct: 4554 TYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALV-------EEPT 4606 Query: 590 TIQGLPGKNVVT------TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIV----TQPK 639 + PG T T E T A I+ R T +++ T P Sbjct: 4607 SYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI 4666 Query: 640 GIGS---TVQPAAKIIP---------------TKIVYGQQGKTQVLIKPKPVTFQATVVS 681 GS T P + P T + T + + T ++ V+ Sbjct: 4667 SSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 4726 Query: 682 EQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIA 741 T + + V E+ G + ++ +SS++S S +S H I+ Sbjct: 4727 TATTPSPARS-TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTIS 4785 Query: 742 SRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTID 801 S S A+ PT + SS AT+ TT ES + D Sbjct: 4786 SPPSTTS----ALVEEPTSYH---SSPGSIATTHFPE----SSTTSGRSEESTASHSSPD 4834 Query: 802 LSQMA-VPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQ 860 + + +P T R + ES + + + +T T G +L S P Sbjct: 4835 TNGITPLPAHFTTSGRIA-ESTTFYISPGSMETTLAST-ATTPGLSAKSTILYSSSRSPD 4892 Query: 861 QPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGT 920 Q P A+ TS +S G T + QA S+HT S T Sbjct: 4893 QTLSP-------------ASMTS-------SSISGEPTSLYSQAESTHTTAFPAST---T 4929 Query: 921 EEGEVEEMDTLDPQTG 936 G +E T + G Sbjct: 4930 TSGLSQESTTFHSKPG 4945 Score = 45.1 bits (105), Expect = 5e-04 Identities = 78/364 (21%), Positives = 137/364 (37%), Gaps = 43/364 (11%) Query: 59 STERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANA 118 ST R+E R + ++ H +S P S++ +E P + T F ++ Sbjct: 4764 STASGRSEESRTSH----SSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFP-ESST 4818 Query: 119 VANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTST-PVPSGSIATVKSPRPASPASN 177 + + + AS P G + + TS ++T + GS+ T + +P Sbjct: 4819 TSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPG-- 4876 Query: 178 VVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSG 237 L + ST+ S D+ P ++S S P L ++ + + SG Sbjct: 4877 ---LSAKSTILYSSSRSPDQTLSPASMT-SSSISGEPTSLYSQAESTHTTAFPASTTTSG 4932 Query: 238 SPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQK-VIIVTTSPSSTFVPNILSK 296 + S S S +SP IT + + + T +Q + T SP+ST VP + + Sbjct: 4933 LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992 Query: 297 SHNYAAVTKLVPTSVIA----------STTQKP----------PVVITAS---QSSLVSN 333 S + + T+ + +T P P +T + Q S + Sbjct: 4993 STTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFH 5052 Query: 334 SSSGSSSSTPSPIPNTVA------VTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPK 387 SSS ++ +TP P +T + T +S +P+ A STS + ST + Sbjct: 5053 SSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASS-STSGLTEESTTFHTSP 5111 Query: 388 SLVS 391 S S Sbjct: 5112 SFTS 5115 >gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo sapiens] Length = 2036 Score = 70.5 bits (171), Expect = 1e-11 Identities = 187/826 (22%), Positives = 291/826 (35%), Gaps = 152/826 (18%) Query: 136 TGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV-LPSGSTVYVKS--- 191 +G E S++STT T +S P + ++ + +SP S P ST +S Sbjct: 338 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 397 Query: 192 -VSCSDEDEKPR---KRRRTNS-----SSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMS 242 S S +D R T S S++SP+ + +P S T G + S Sbjct: 398 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTT----TPGLSERS 453 Query: 243 NIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTS-PSSTFVPNILSKSHNYA 301 S S +SP T + S ++T + ++ TT+ P ST P + S Sbjct: 454 TTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSH 513 Query: 302 AVTKLVPTSVI-ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTV---------- 350 + T+++ ASTT P SQ S S+SSSGS+ + SP T Sbjct: 514 SSPGSTDTTLLPASTTTSGP-----SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 568 Query: 351 -----------------------AVTAVVSST--------PSVVMSTVAQGVSTS-AIKM 378 A T V SST P+ S QG ST+ Sbjct: 569 HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 628 Query: 379 ASTR-LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQ 437 AST PSP S +AP + + + +P T ++ S + H Sbjct: 629 ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF--PASSTTSGHSEKSTIFHSSPDAS 686 Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQP--SKILPKPVTATLPTSSNSPIMVVSS----- 490 P T + ES T ++ P ++I P + T P S + SS Sbjct: 687 GTTPSSAHSTTSGRGES----TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 742 Query: 491 ---NGAIMTTKLV---TTPTGTQATYTRPTVSPSIGRMAATPG-----AATYVKTTSGSI 539 + A MT+ V +T + +Q T TVSP+ TPG Y + + Sbjct: 743 TTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA---STTTPGLSEESTTVYSSSRGSTE 799 Query: 540 ITVVPKSLAT-LGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKN 598 TV P S T + G+ ++ +T T S + + + T G+ G Sbjct: 800 TTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 859 Query: 599 VVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQ-------PKGIGSTVQPAAKI 651 T + G E T +G+ L+ R T +V + P +T P + Sbjct: 860 ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 919 Query: 652 IPTKIVYGQQGKTQVLIKPKPVTFQATVVS-EQTRQLVTETLQQASRVAEAGNSSIQEGK 710 P+ + K TF + S + T T T S E+ S Q G Sbjct: 920 TPS-------------LSEKSTTFYTSPRSPDATLSPATTTSSGVSE--ESSTSHSQPGS 964 Query: 711 EEPQNYTDSSSSSTES-----SQSSQDSQPVVHVIASR------RQDWSEHEIAMETSPT 759 + DS+++S S S SSQ S S +Q + H +T T Sbjct: 965 THTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 1024 Query: 760 IIYQD--------VSSESQSAT----------STIKALLELQQTTVKEKLESKPRQPTID 801 ++ D S+ + S+T S+ A L+ + TT + S P+ Sbjct: 1025 LLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS-P 1083 Query: 802 LSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEV 847 A P++++ P S + A T R++E T V Sbjct: 1084 PGTTAAPVEVSTTYHSRPSS----TPTTHFSASSTTLGRSEESTTV 1125 Score = 57.4 bits (137), Expect = 9e-08 Identities = 266/1346 (19%), Positives = 440/1346 (32%), Gaps = 180/1346 (13%) Query: 77 TTIAHNMSGPNSS--SEWSIEGRRLVPLMPRLVPQTAFTVTA----NAVANAAIQHNASL 130 +T +H+ GP + S S L P + T T N A+ ++ AS+ Sbjct: 179 STASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE--ASM 236 Query: 131 PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLP-------S 183 PV + T S STT ST S + K RPA P + + S Sbjct: 237 PVHSSTRSPHTTLSPAGSTTRQGESTTFHSW--PSSKDTRPAPPTTTSAFVEPSTTSHGS 294 Query: 184 GSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSN 243 S++ +S + T SS P++ + S S Sbjct: 295 PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 354 Query: 244 IMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAV 303 I + + + P + ST TT+ TTS S + S S A Sbjct: 355 ISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS----TTSGRSE--ESTASHSSQDATG 408 Query: 304 TKLVP----TSVIASTTQKPPVVITASQSSLVSNSSS----GSSSSTPSPIPNTVAVTAV 355 T ++P TSV+ + P+ + +++ + S++ S+T P + A T Sbjct: 409 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 468 Query: 356 VSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQV 415 +ST S S V++ +TS + ST + + P Sbjct: 469 PASTTS---SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 525 Query: 416 QQQTQQQVAQPSPVSHQQQ-PQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT 474 T +Q S SH + L PG + QES + + P T Sbjct: 526 ASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTT 585 Query: 475 ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTG-----------TQATYTRPTVSPSIGRMA 523 ++ +++ V SS G+ TT + T T T T SP A Sbjct: 586 SSGIVEAST--RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATA 643 Query: 524 ATPGAATYVKTTSGSIITVVPKSLATLG----GKIISSNIVSGTTTKITTIPMTSKPNVI 579 + TY ++ + T P S T G I S+ + TT + TS Sbjct: 644 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 703 Query: 580 VVQKTTGKGTTIQGLPGKNVVTTLLNAGGE--KTIQTVPTGAKPAILTATRPITKMIV-- 635 + + T I LPG L A + ++ T PA +T+ + Sbjct: 704 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 763 Query: 636 TQPKGIGSTVQPAAKIIP------TKIVYGQQGKTQVLIKP----------KPVTFQATV 679 +QP STV PA+ P T + +G T+ + P +P TF + Sbjct: 764 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRP 823 Query: 680 VSEQ----TRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQP 735 S T T L + S +S Q G D ST SS + Sbjct: 824 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 883 Query: 736 VVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKP 795 + S + + E++P+ + S S + T+T+ P Sbjct: 884 KLSPARS-----TTSGLVGESTPSRL-----SPSSTETTTL------------------P 915 Query: 796 RQPTI-DLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT--EVAFPLL 852 PT LS+ + + + SP A S V+E +T + G+ AFP Sbjct: 916 GSPTTPSLSEKSTTFYTSPRSPDATLSP--ATTTSSGVSEESSTSHSQPGSTHTTAFPDS 973 Query: 853 VSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFT 912 + Q+P+ SQ +T+ ++ S ASS G QQ+ + H++ Sbjct: 974 TTTSDLSQEPTTSH--------SSQGSTEATLSPGSTTASSLG------QQSTTFHSS-- 1017 Query: 913 KHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQT---QLQVKTL 969 G E + DT+ +GL S T S + P + Q + T Sbjct: 1018 -----PGDTETTLLPDDTI--TSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF 1070 Query: 970 QCFQTKQKQT--------IHLQADQLQHKLPQMPQLSIRHQKLTPL--QQEQAQPKPDVQ 1019 Q + + T ++ H P + T L +E Sbjct: 1071 QSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPG 1130 Query: 1020 HTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPK---IYVQPQTPQS 1076 T + L+ +P + + + +TT A K Y P++P + Sbjct: 1131 ATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 1190 Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEG--RQPPTVTKITGGSSVPKLTSPVTS 1134 +S PAS+ S+ ++ S F G P + T S P T T+ Sbjct: 1191 TLS-PASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD--TT 1247 Query: 1135 ISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSML---TGEAGSLPSTH 1191 +SP + + + +T + P A+ +L T S S H Sbjct: 1248 LSPGSTTASSLGPESTTFHSSPGSTETTL------LPDNTTASGLLEASTPVHSSTGSPH 1301 Query: 1192 MVVAGMANSTPQQQ--------KCRESCSSPSTVGSS---LTTRKIDPPAVPATGQFMRI 1240 ++ ++T Q + +++ +P T S+ L+T P+ T F Sbjct: 1302 TTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 1361 Query: 1241 QNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPS-------GLLELNNFTSQQLDD 1293 + E + A P S+++ +VE S G + +F Sbjct: 1362 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 1421 Query: 1294 EETAMEQDIDSSTEDGTEPSPSQSSA 1319 + + SST PS +SA Sbjct: 1422 GRSEESRTSHSSTTHTISSPPSTTSA 1447 Score = 55.8 bits (133), Expect = 3e-07 Identities = 206/906 (22%), Positives = 321/906 (35%), Gaps = 161/906 (17%) Query: 136 TGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCS 195 +G E + STT T +STP + ++A S + ++ ST+ +S Sbjct: 10 SGHSEESATFHGSTTHTKSSTPSTTAALAHT-SYHSSLGSTETTHFRDSSTISGRSEESK 68 Query: 196 DEDEKPRKRRRT---NSSSSSPVVLKEVPKAVVPVS-KTITVPVS----GSPKMSNIMQS 247 P T S+ S +V P + S +T +P S G + S S Sbjct: 69 ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYS 128 Query: 248 IANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTS-PSSTFVPNI-----LSKSHNYA 301 S P +T + S ++T + ++ TT+ P ST +P + S S Sbjct: 129 SPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 188 Query: 302 AVTKLVPTSVIAST----------------TQKPPVVITAS---QSSLVSNSSSGSSSST 342 T L P S AS+ T P TAS ++S+ +SS+ S +T Sbjct: 189 TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTT 248 Query: 343 PSPIPNTV--AVTAVVSSTPSVVMSTVAQGVSTSA-IKMASTRLPSPKSL------VSAP 393 SP +T + S PS + A +TSA ++ ++T SP S+ + Sbjct: 249 LSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARST 308 Query: 394 TQILAQFPKQHQQSP--KQQLYQVQQQTQQQVAQPSPVSHQ-----------------QQ 434 T L + + SP Q ++ + T + S SH ++ Sbjct: 309 TSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE 368 Query: 435 PQQSPLPPGIKPTIQI---------KQESGVKIITQQVQPSKILPKPVTAT--LPTSSNS 483 P PG T +ES +Q + +LP T + L S+ S Sbjct: 369 PTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 428 Query: 484 PIMVVSSNGAIMTTKL---VTTPTGTQATYT--------RPTVSPSIGRMAATPGAATYV 532 PI S+G++ TT L TTP ++ + T T+SP+ + +T Sbjct: 429 PI----SSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 484 Query: 533 KTTSGSI-ITVVPKSLATLG----GKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGK 587 ++ GS T P S T G S+ S TT + TS P+ + Sbjct: 485 RSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSS 544 Query: 588 GTTIQGL-PGKNVVTTLLNAGGEK-TIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTV 645 G+T L PG TT L+ G E T + P + + + ++ + ST Sbjct: 545 GSTDTALSPGS---TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 601 Query: 646 QPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSS 705 P + P T ++ + FQ S T T + V E+ Sbjct: 602 SPRTTLSPA-------SSTSPGLQGESTAFQTHPASTHTTPSPPST--ATAPVEESTTYH 652 Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDV 765 G ++ SS++S S +S+ + H A T+P+ + Sbjct: 653 RSPGSTPTTHFPASSTTSGHSEKST-----IFH----------SSPDASGTTPSSAHSTT 697 Query: 766 SSESQSATSTIK----ALLELQQTTVKEKLE-------SKPRQPTIDLSQMAVPIQMTQE 814 S +S TS I + L +T L S PR PT LS P MT Sbjct: 698 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS----PASMT-- 751 Query: 815 KRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVA 874 S V E TT R+ G+ + VS S + T + + Sbjct: 752 --------------SLGVGEESTTSRSQPGSTHS---TVSPASTTTPGLSEESTTV--YS 792 Query: 875 QSQTATQTSVVVKSIPASSPG-AITHIMQQALSSHTA-FTKHSEELG-TEEGEVEEMDTL 931 S+ +T+T+V S S G T + S+HT FT+ S G TEE Sbjct: 793 SSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 852 Query: 932 DPQTGL 937 QTGL Sbjct: 853 STQTGL 858 Score = 46.6 bits (109), Expect = 2e-04 Identities = 81/322 (25%), Positives = 121/322 (37%), Gaps = 44/322 (13%) Query: 85 GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCY 144 GP S++ S G L+P N A+ ++ AS PV + TGS Sbjct: 1259 GPESTTFHSSPGSTETTLLPD-----------NTTASGLLE--ASTPVHSSTGSPHTTLS 1305 Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204 STT ST S + P P + S V L + S P Sbjct: 1306 PAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS------------HGSPSST 1353 Query: 205 RRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKI-TF 263 T+ S+SS + + V S + + SP S + S H SP T Sbjct: 1354 PTTHFSASSTTLGRSEESTTVH-SSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM 1412 Query: 264 TKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS-----TTQK 318 P + T + +++ TS SST + +S + + PTS +S TT Sbjct: 1413 HFPESSTASGRSEE---SRTSHSST--THTISSPPSTTSALVEEPTSYHSSPGSIATTHF 1467 Query: 319 PPVVITA--SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSST----PSVVMSTVAQGVS 372 P T+ S+ S S+SS ++ TP P T + S+T P + +T+A + Sbjct: 1468 PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTAT 1527 Query: 373 TSAIKMASTRLPSPKSLVSAPT 394 T + ST L + LV PT Sbjct: 1528 TPGLSAKSTILYT-SDLVGEPT 1548 Score = 40.0 bits (92), Expect = 0.015 Identities = 214/1117 (19%), Positives = 358/1117 (32%), Gaps = 149/1117 (13%) Query: 320 PVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS---------------------- 357 P T S S S + GS++ T S P+T A A S Sbjct: 4 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63 Query: 358 --------STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPK 409 S+P + +TV ST ++ + PSP S S T L + S K Sbjct: 64 SEESKASHSSPDAMATTVLPAGSTPSV-LVGDSTPSPISSGSMETTALPGSTTKPGLSEK 122 Query: 410 QQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLP---PGIKPTIQIKQESGVKIITQQVQPS 466 + ++ P+ ++ ++S PG T + + ++Q+ S Sbjct: 123 STTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTAS 182 Query: 467 KILPKPVTATLPTSSNSPIMV-------VSSNGAIMTTKL-----------VTTPTGTQA 508 P P TL S + + S G+ TT L + P + Sbjct: 183 HSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSST 242 Query: 509 TYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKIT 568 T+SP+ G + T+ S P + + + +++ S ++ T Sbjct: 243 RSPHTTLSPA-GSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT 301 Query: 569 TIPMTSKPNVIVVQKTT---GKGTT-------IQGLPGKNVVTTLLNAGGEKTIQTVPTG 618 I S + +V + TT G+T G+ +T ++ TI + P+ Sbjct: 302 HISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST 361 Query: 619 AKPAI-----------LTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVL 667 + TAT T + ST +++ IV + T VL Sbjct: 362 TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL 421 Query: 668 IKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESS 727 + ++T + + T L ++ S T S +ST SS Sbjct: 422 LG------ESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSS 475 Query: 728 QSSQDSQPVVHVIASRRQDWSEHEIAMETSPTI--IYQDVSSESQSATSTIKALLELQQT 785 S++S SR + S H A S T + + ++ S ST LL T Sbjct: 476 GVSEES------TTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 529 Query: 786 TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845 T ES + + A+ T ES + T G Sbjct: 530 TSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGI 589 Query: 846 EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905 A + S P+ P + + TA QT S P T ++++ Sbjct: 590 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 649 Query: 906 SSH----TAFTKHSEELGTEEGEVEE---MDTLDPQTGLFYRSALTQSQSAKQQKLSQPP 958 + H + T H T G E+ + +G SA + + + S+ Sbjct: 650 TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR-- 707 Query: 959 LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPL-QQEQAQPKPD 1017 + ++ TL T + +A + P+ P ++ +T L E++ Sbjct: 708 ISPGSTEITTLPGSTTTPGLS---EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 764 Query: 1018 VQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQ 1077 + H V+ P P + +++ + P+ V + P + Sbjct: 765 QPGSTHSTVS-----PASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTF 819 Query: 1078 MSLPAS------SEKQTASQVEQ--------PIITQ-GSSVTKITFEGRQPPTVTKITGG 1122 S PAS +E T S + + P TQ G T T + + T + G Sbjct: 820 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 879 Query: 1123 SSVPKLT------------SPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDP 1170 S+ KL+ S + +SP T SL E D Sbjct: 880 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 939 Query: 1171 P-KKALATSMLTGEAGSLP-----STHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTR 1224 A TS E S STH +ST +E +S S+ GS+ T Sbjct: 940 TLSPATTTSSGVSEESSTSHSQPGSTH--TTAFPDSTTTSDLSQEPTTSHSSQGSTEATL 997 Query: 1225 KIDPPAVPATGQFMRI--QNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLE 1282 + GQ + G + P + I + + + P HSS+ + L Sbjct: 998 SPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL---HTTLT 1054 Query: 1283 LNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSA 1319 + TS L +E T + SS T PSP ++A Sbjct: 1055 PASSTSAGLQEESTTFQSWPSSS---DTTPSPPGTTA 1088 >gi|38788274 bromodomain PHD finger transcription factor isoform 1 [Homo sapiens] Length = 2920 Score = 70.5 bits (171), Expect = 1e-11 Identities = 198/1025 (19%), Positives = 367/1025 (35%), Gaps = 120/1025 (11%) Query: 114 VTANAVANAAIQHNASLPVPAETGSKEVV------CYSYTSTTSTPT----STPVPSGSI 163 +T + + + + E G K+ V C T TT+T T STP GS+ Sbjct: 1585 ITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSV 1644 Query: 164 ATVKSPRPASPASNVVVLPSGSTV---YVKSVSCSDEDE--------KPRKRRRTNSSSS 212 + + V S +T V S++ S E K + ++T S ++ Sbjct: 1645 DIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTA 1704 Query: 213 SPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS----PVKITFTKPST 268 P K V K S ++ V + + + + P+ + P + PS Sbjct: 1705 LPSYRKFVTK-----SSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSP 1759 Query: 269 QTTNTTTQKVIIVTTSPSS--TFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS 326 + T T + + T + + + +L S + + P + T+ IT + Sbjct: 1760 RPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTT 1819 Query: 327 QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP 386 + ++ G + V TP + +G+ +SA++ P Sbjct: 1820 E--IIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQ 1877 Query: 387 KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKP 446 V T + + + +L++++ ++ + + QQ ++ Sbjct: 1878 TGPVIIETWVAEE---------ELELWEIRAFAERVEKEKAQAVEQQAKKR--------- 1919 Query: 447 TIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMT-TKLV-TTPT 504 ++Q+ I T P+ + T S +MV +G++ T TK+V TT Sbjct: 1920 ---LEQQKPTVIATSTTSPTS------STTSTISPAQKVMVAPISGSVTTGTKMVLTTKV 1970 Query: 505 GTQATYTRPTVSPSIGRMAATPGAATYVKT--TSGSIITVVPKSLATLGGKIISSNIVSG 562 G+ AT T AT+VK ++ ++ V K L + +S + Sbjct: 1971 GSPATVTFQQ------NKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQ-QTF 2023 Query: 563 TTTKITTIPMTSKPNVIVVQKTTGKGTTIQG---LPGKNVVTTLLNAG--GEKTIQT--- 614 T+ + T +T +PN TT I G PG V+ T L G+ I+T Sbjct: 2024 TSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVM 2083 Query: 615 VPTGAKPAILTAT---RPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPK 671 V GA ++T +P++ V+ P + ST + T Q +Q P+ Sbjct: 2084 VQPGAPQQVMTQIIRGQPVSTA-VSAPNTVSSTPGQKSLTSATSTSNIQSSASQ---PPR 2139 Query: 672 PVTFQATVVSEQTRQLVTET--LQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQS 729 P Q + Q QL Q + V + + + + PQ T + Q+ Sbjct: 2140 PQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQA 2199 Query: 730 SQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKE 789 + + V + + + T+ T + + + S + +++ Q Sbjct: 2200 AMPNGTVQRFLFT---PLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLP 2256 Query: 790 KLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAF 849 +S P Q A P Q + P+SP+ V+++ + TT + +E Sbjct: 2257 PAQSSSVGPAEAQPQTAQPSAQPQPQTQ-PQSPAQPEVQTQPEVQTQTTVSSHVPSEAQP 2315 Query: 850 PLLVSHRSQPQQPSQPQRTLL-QHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908 S + Q SQPQ + Q + Q+ +QT + + SPG + + Q S Sbjct: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQV-QTTTSQP 2374 Query: 909 TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968 H+ +G+ + + T L+ Q+ Q +S P Q Q+Q Sbjct: 2375 IPIQPHTSLQIPSQGQPQSQPQVQSST-----QTLSSGQTLNQVTVSSPSRPQLQIQ--- 2426 Query: 969 LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAK 1028 Q Q + QLQ ++ + Q+ + + Q QAQ Q + + + Sbjct: 2427 -------QPQPQVIAVPQLQQQVQVLSQIQSQ-----VVAQIQAQQSGVPQQIKLQLPIQ 2474 Query: 1029 DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088 +Q + Q VV V A +QL ++QQ +Q Q + Q Q+ + Q Sbjct: 2475 IQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQ-----QQKKKQQQIEIKREHTLQA 2529 Query: 1089 ASQVE 1093 ++Q E Sbjct: 2530 SNQSE 2534 Score = 52.0 bits (123), Expect = 4e-06 Identities = 111/589 (18%), Positives = 204/589 (34%), Gaps = 87/589 (14%) Query: 24 ELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNM 83 E+ A+A + +AQ + KK L + V++ ST + ++ + +A Sbjct: 1896 EIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPIS 1955 Query: 84 SGPNSSSEWSIEGRRLVPL-----MPRLVPQTAFTVTANAVANAAI---QHNASLPVPAE 135 + ++ + + P + QT T +N+ + Q +P+ Sbjct: 1956 GSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSS 2015 Query: 136 TGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPAS-----PASNVVVLPSGSTVYVK 190 TG+ + S+ T+T T P SGS T + + + P V+ P + K Sbjct: 2016 TGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGK 2075 Query: 191 SVSCSDEDEKPRKRRR--TNSSSSSPV-VLKEVPKAV--VPVSKTITVPVSGSPKMSNIM 245 ++ + +P ++ T PV P V P K++T S SNI Sbjct: 2076 AIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATS----TSNIQ 2131 Query: 246 QSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK 305 S + P VK+T + + T + + V ++ + Sbjct: 2132 SSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTV-----------VIQGQGQTTGQLQ 2180 Query: 306 LVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMS 365 L+P V ++ A + V + +A TA +ST + +S Sbjct: 2181 LIPQGVTVLPGPGQQLMQAAMPNGTVQRF-----------LFTPLATTATTASTTTTTVS 2229 Query: 366 TVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQ 425 T A G S ++ + P Q + P + Q QT Q AQ Sbjct: 2230 TTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPA-----------EAQPQTAQPSAQ 2278 Query: 426 PSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP--TSSNS 483 P P + Q P Q P +Q + E + PS+ P ++ P + + Sbjct: 2279 PQPQTQPQSPAQ--------PEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQ 2330 Query: 484 PIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV 543 P SN + V +P+ T+ + P+ +PG + V+TT+ I + Sbjct: 2331 P----QSNVQGQSPVRVQSPSQTRIRPSTPS--------QLSPGQQSQVQTTTSQPIPIQ 2378 Query: 544 PKSLATLGG----------KIISSNIVSGTTTKITTIPMTSKPNVIVVQ 582 P + + + + + SG T T+ S+P + + Q Sbjct: 2379 PHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ 2427 Score = 50.8 bits (120), Expect = 8e-06 Identities = 178/1024 (17%), Positives = 340/1024 (33%), Gaps = 111/1024 (10%) Query: 171 PASPASNVVVLPSGSTVYVKS-VSCSDEDEKPRKRRRTNSSSSSPVV------LKEVPKA 223 P + ++ V S ++ V D +E+ +++ SSS L+ +P Sbjct: 1448 PENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPST 1507 Query: 224 VVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTT 283 S T P + P+ +++ Q + S VK + P T + I Sbjct: 1508 KESDSTQTTTPSASCPESNSVNQ--VEDMEIETSEVKKVTSSPITSEEESNLSNDFIDEN 1565 Query: 284 SPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTP 343 N+ +S +T++ + +T K + + V +S+ + ST Sbjct: 1566 GLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTV 1625 Query: 344 SPIPNTVAVTAVVSSTPSV-VMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPK 402 + TV + S+ SV ++S Q + + + + +LV++ T K Sbjct: 1626 TTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMT-----VSK 1680 Query: 403 QHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQ---ESGVKII 459 ++ K +L + + + + P + + S + P +K+ + G++ Sbjct: 1681 EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIR-- 1738 Query: 460 TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSI 519 +V KP P S P ++ + T K + + + Sbjct: 1739 --EVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDM 1796 Query: 520 GRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSN---------IVSGTTTKITTI 570 A G T +T+ I T +G I S I T K T Sbjct: 1797 AAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPT 1856 Query: 571 PMTS-------KPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKT----IQTVPTGA 619 P +P K TG + + + + A E+ Q V A Sbjct: 1857 PQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQA 1916 Query: 620 KPAILTATRPITKMIVTQP-KGIGSTVQPAAKIIPTKIVYGQQGKTQVLI-----KPKPV 673 K + + T P ST+ PA K++ I T++++ P V Sbjct: 1917 KKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATV 1976 Query: 674 TFQ---------ATVVSE-QTRQLVTETLQQASRVAEAGNSSIQEG--KEEPQNYTDSSS 721 TFQ AT V + Q+ V + Q+ + + + Q+ +P+ T + Sbjct: 1977 TFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIR 2036 Query: 722 SSTESSQSSQDSQPVVHVIASR------RQDWSEHEIAMETSPTIIYQDVSSESQSATST 775 +T S + + V+ R R + + T + + Q T Sbjct: 2037 PNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQI 2096 Query: 776 IKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVA-- 833 I+ + + S P Q ++ + IQ + + P+ + + ++L Sbjct: 2097 IRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLT 2156 Query: 834 ------EYITTERTDEGTEVA--------FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTA 879 + +T +G +L Q Q + P T+ + + Sbjct: 2157 QGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLAT 2216 Query: 880 TQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGL-- 937 T T+ + S+ A T +Q+ S + L + PQT Sbjct: 2217 TATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPS 2276 Query: 938 FYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQL 997 TQ QS Q ++ P QTQ T+ + Q H Q+ + Q PQ Sbjct: 2277 AQPQPQTQPQSPAQPEVQTQPEVQTQT---TVSSHVPSEAQPTHAQSSKPQVAAQSQPQS 2333 Query: 998 SIRHQKLTPLQQ-EQAQPKPDVQHTQHPMVAKDRQLPTLMAQP----PQTVVQVLAVKTT 1052 +++ Q +Q Q + +P P + Q+ T +QP P T +Q+ + Sbjct: 2334 NVQGQSPVRVQSPSQTRIRPSTPSQLSP--GQQSQVQTTTSQPIPIQPHTSLQIPSQGQP 2391 Query: 1053 QQLPKLQQA-----------------PNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQP 1095 Q P++Q + P++P++ +Q PQ + Q SQ++ Sbjct: 2392 QSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQ 2451 Query: 1096 IITQ 1099 ++ Q Sbjct: 2452 VVAQ 2455 Score = 39.3 bits (90), Expect = 0.025 Identities = 69/326 (21%), Positives = 117/326 (35%), Gaps = 59/326 (18%) Query: 150 TSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNS 209 T+ P++ P P +P SPA P T + P + + T++ Sbjct: 2272 TAQPSAQPQPQ--------TQPQSPAQ-----PEVQTQPEVQTQTTVSSHVPSEAQPTHA 2318 Query: 210 SSSSP-VVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP-HMSPVKITFTKPS 267 SS P V + P++ V + V SP + I S + L P S V+ T ++P Sbjct: 2319 QSSKPQVAAQSQPQSNVQGQSPVRVQ---SPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2375 Query: 268 TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327 +T+ Q + + P + S + ++ L V S+ +P + I Q Sbjct: 2376 PIQPHTSLQ----IPSQGQPQSQPQVQSSTQTLSSGQTL--NQVTVSSPSRPQLQIQQPQ 2429 Query: 328 SSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPK 387 +++ +P V+S S V++ + S Sbjct: 2430 PQVIA-------------VPQLQQQVQVLSQIQSQVVAQIQAQQS--------------- 2461 Query: 388 SLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPT 447 P QI Q P Q QQS Q +Q+Q Q A + Q + + Sbjct: 2462 ---GVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQ 2518 Query: 448 IQIKQESGVKIITQQVQPSKILPKPV 473 I+IK+E ++ Q S+I+ K V Sbjct: 2519 IEIKREHTLQASNQ----SEIIQKQV 2540 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.120 0.323 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 50,430,305 Number of Sequences: 37866 Number of extensions: 2474227 Number of successful extensions: 22848 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 147 Number of HSP's successfully gapped in prelim test: 753 Number of HSP's that attempted gapping in prelim test: 11806 Number of HSP's gapped (non-prelim): 5311 length of query: 1322 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1208 effective length of database: 13,930,794 effective search space: 16828399152 effective search space used: 16828399152 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.