Guide to the Human Genome
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Search of human proteins with 19923559

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923559 EMSY protein [Homo sapiens]
         (1322 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923559 EMSY protein [Homo sapiens]                              2536   0.0  
gi|91982772 mucin 17 [Homo sapiens]                                   108   3e-23
gi|83367077 mucin 16 [Homo sapiens]                                    94   7e-19
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       91   1e-17
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            87   1e-16
gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap...    84   7e-16
gi|116284392 mucin 2 precursor [Homo sapiens]                          84   1e-15
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              81   6e-15
gi|161019170 mucin 5AC [Homo sapiens]                                  81   8e-15
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            80   1e-14
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            80   2e-14
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            80   2e-14
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            80   2e-14
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            80   2e-14
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            80   2e-14
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            80   2e-14
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            80   2e-14
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            80   2e-14
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    79   3e-14
gi|167736355 mucin 4 isoform a [Homo sapiens]                          78   5e-14
gi|98986457 host cell factor 1 [Homo sapiens]                          77   1e-13
gi|151301154 mucin 6, gastric [Homo sapiens]                           77   1e-13
gi|56549696 E1A binding protein p400 [Homo sapiens]                    75   3e-13
gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti...    75   5e-13
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti...    74   7e-13
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   74   1e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   74   1e-12
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        70   1e-11
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    70   1e-11
gi|38788274 bromodomain PHD finger transcription factor isoform ...    70   1e-11

>gi|19923559 EMSY protein [Homo sapiens]
          Length = 1322

 Score = 2536 bits (6574), Expect = 0.0
 Identities = 1322/1322 (100%), Positives = 1322/1322 (100%)

Query: 1    MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSIST 60
            MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSIST
Sbjct: 1    MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSIST 60

Query: 61   ERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVA 120
            ERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVA
Sbjct: 61   ERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVA 120

Query: 121  NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV 180
            NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV
Sbjct: 121  NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV 180

Query: 181  LPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPK 240
            LPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPK
Sbjct: 181  LPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPK 240

Query: 241  MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300
            MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY
Sbjct: 241  MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300

Query: 301  AAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP 360
            AAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP
Sbjct: 301  AAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP 360

Query: 361  SVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ 420
            SVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ
Sbjct: 361  SVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ 420

Query: 421  QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS 480
            QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS
Sbjct: 421  QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS 480

Query: 481  SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII 540
            SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII
Sbjct: 481  SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII 540

Query: 541  TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV 600
            TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV
Sbjct: 541  TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV 600

Query: 601  TTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQ 660
            TTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQ
Sbjct: 601  TTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQ 660

Query: 661  QGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSS 720
            QGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSS
Sbjct: 661  QGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSS 720

Query: 721  SSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL 780
            SSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL
Sbjct: 721  SSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL 780

Query: 781  ELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTER 840
            ELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTER
Sbjct: 781  ELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTER 840

Query: 841  TDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHI 900
            TDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHI
Sbjct: 841  TDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHI 900

Query: 901  MQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE 960
            MQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE
Sbjct: 901  MQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE 960

Query: 961  QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQH 1020
            QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQH
Sbjct: 961  QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQH 1020

Query: 1021 TQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
            TQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSL
Sbjct: 1021 TQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
            PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA
Sbjct: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS
Sbjct: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200

Query: 1201 TPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAI 1260
            TPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAI
Sbjct: 1201 TPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAI 1260

Query: 1261 PQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAE 1320
            PQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAE
Sbjct: 1261 PQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAE 1320

Query: 1321 RS 1322
            RS
Sbjct: 1321 RS 1322


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  108 bits (271), Expect = 3e-23
 Identities = 256/1279 (20%), Positives = 431/1279 (33%), Gaps = 141/1279 (11%)

Query: 52   LSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIE----GRRLVPLMPRLV 107
            LS  L +S+E               TT     S P ++   SI+      R  PL    V
Sbjct: 1992 LSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPV 2051

Query: 108  PQTAF---------TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTST--TSTPTST 156
              T           T   ++         AS    AE  S  +   S  S   TS P ST
Sbjct: 2052 STTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLST 2111

Query: 157  PVPSGSIATVKSPRPASPASNVVVLP--SGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSP 214
               +   A+  S  P    S V+     S S +  +  S        R+   T+   S+ 
Sbjct: 2112 TPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTT 2171

Query: 215  VVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVK--ITFTKPSTQTTN 272
            VV       +       + PV+ S +  +   +   +  P  +P +    FT     T  
Sbjct: 2172 VVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMP 2231

Query: 273  TTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK---LVPTSVIASTTQKPPVVITASQSS 329
              T +   ++ +P  T  P   S     +  T     +PTS ++  T   P+       +
Sbjct: 2232 VVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTT--PLTSIPVSHT 2289

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAI-KMASTRLPSPKS 388
            LV+NS   + S+TP    NT   T+  +S+P       +   STS+      TR+P   +
Sbjct: 2290 LVANSEVSTLSTTPVD-SNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTT 2348

Query: 389  LVSA-PTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPT 447
            +V++  T  L+  P                 T  Q       +       S    G  P 
Sbjct: 2349 MVASFETSTLSTTPADTS---------TPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPL 2399

Query: 448  IQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV---TTPT 504
              +   S + +++ +       P   +  + TS+ +     ++ G  + T      TTP 
Sbjct: 2400 TSVPV-STMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 2458

Query: 505  GTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT--------VVPKSLATLGGKIIS 556
             +    T P VS   G ++ TP   +   TTS    +        VVP S A+ G  +++
Sbjct: 2459 ASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLT 2518

Query: 557  SNIVSGT------TTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEK 610
            S  VS T       + ++T P+ S   V+   + +   T+ +G      + T   + G  
Sbjct: 2519 SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEG----TSMPTSTYSEGST 2574

Query: 611  TIQTVPTGAKP-----AILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ---G 662
             ++++P   KP     A   +T P+   I        S+    AK     I    +    
Sbjct: 2575 PLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTS 2634

Query: 663  KTQVLIKPKPV-TFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSS 721
             T +L+   PV + +A+ +S  T  + T TL   S     G SS         + T +  
Sbjct: 2635 LTSILVSTMPVASSEASTLS--TTPVDTRTLVTTS----TGTSS---------SPTTAEG 2679

Query: 722  SSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLE 781
            SS  +S   + S P+ +++ S     +     + T+P      V++ +++++S   A   
Sbjct: 2680 SSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTA--- 2736

Query: 782  LQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHS--------PESPSIAVVESELVA 833
             + T+++    S    P   +    +P+  ++    S        P + S     S   A
Sbjct: 2737 -EGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTA 2795

Query: 834  EYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASS 893
            E +T+  T   +E + PL     +     S    TL      + T   TS    S P ++
Sbjct: 2796 E-VTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854

Query: 894  PGAITHIMQQALSSH--TAFTKHSEELGTEEG---EVEEMDTLDPQTGLFYRSALTQSQS 948
             G +  I   +  S   T+    +  + + E        +DT  P T     S+   +  
Sbjct: 2855 EGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE 2914

Query: 949  AKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLT--- 1005
                 +S P    T L    +        +   L    +  + P            T   
Sbjct: 2915 GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEG 2974

Query: 1006 ---PLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAP 1062
               P+     +  P    +   M     +  TL   P  T   V         P   +  
Sbjct: 2975 TSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGT 3034

Query: 1063 NQP-KIYVQPQTPQSQMSL--------PASSEKQTASQVEQPIITQGS-SVTKITFEGRQ 1112
              P     +  TP + + +         AS+   T      P++T    S +    EG  
Sbjct: 3035 GIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTS 3094

Query: 1113 PPTVTKITGG---SSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVD 1169
             P  T   G    + VP  T+PVTS S I     T V            + T+ E     
Sbjct: 3095 MPISTYSEGSTPLTGVPVSTTPVTS-SAISTLSTTPVD-------TSTPVTTSTEAHSSP 3146

Query: 1170 PPKKALATSMLTGEAGSLPSTHMVVAGM---------ANSTPQQQK-----CRESCSSPS 1215
               +  +    T   GS P T+M V+ M          ++TP           E+ SS +
Sbjct: 3147 TTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTT 3206

Query: 1216 TVGSSLTTRKIDPPAVPAT 1234
              G+S+ T        P T
Sbjct: 3207 AEGTSIPTSTPSEGMTPLT 3225



 Score =  108 bits (269), Expect = 4e-23
 Identities = 229/1138 (20%), Positives = 414/1138 (36%), Gaps = 133/1138 (11%)

Query: 145  SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204
            S  STT   TS PV + S  T  SP  A   S  +  PS  +  + S+  S     P   
Sbjct: 2592 STLSTTPVDTSIPVTT-STETSSSPTTAKDTSMPISTPSEVSTSLTSILVST---MPVAS 2647

Query: 205  RRTNSSSSSPVVLKEV----------PKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP 254
               ++ S++PV  + +          P      S   + P   S  ++NI+  ++ +L  
Sbjct: 2648 SEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNIL--VSTTLLA 2705

Query: 255  HMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS 314
            +     ++ T   T T  TT+ +     T+   T +  I + S     +T ++ +++  +
Sbjct: 2706 NSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM-RISTPSDGSTPLTSILVSTLPVA 2764

Query: 315  TTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS------------- 361
            +++   V  TA  +S+   +S+ +SSS     P T  VT++ +STPS             
Sbjct: 2765 SSEASTVSTTAVDTSIPVTTSTEASSS-----PTTAEVTSMPTSTPSETSTPLTSMPVNH 2819

Query: 362  -VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ 420
              V S+ A  +ST+ +  ++    S K+  S  T      P          L  +   T 
Sbjct: 2820 TPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST- 2878

Query: 421  QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKI-LPKPVTATLPT 479
                  +PV+  +    S  P      +    E      T +     I  P  V+  L +
Sbjct: 2879 ------TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTS 2932

Query: 480  SSNSPIMVVSSNGAIMTTKLV--TTPTGTQA-TYTRPTVSPSIGRMAATPG-AATYVKTT 535
               S + V  S  + ++T  V   TP  T A   + PT +       +TPG   T + + 
Sbjct: 2933 ILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSM 2992

Query: 536  SGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLP 595
            S S + V     +TL      ++    T+T+ ++ P T++   I +   +   T +  +P
Sbjct: 2993 SVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIP 3052

Query: 596  GKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTK 655
               V TT +      T+ T P  +   ++T+T      + + P     T  P +      
Sbjct: 3053 ---VSTTPVAIPEASTLSTTPVDSNSPVVTSTE-----VSSSPTPAEGTSMPISTYSE-- 3102

Query: 656  IVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQN 715
               G    T V +   PVT  A + +  T  + T T              +    E   +
Sbjct: 3103 ---GSTPLTGVPVSTTPVTSSA-ISTLSTTPVDTST-------------PVTTSTEAHSS 3145

Query: 716  YTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATST 775
             T S  +S  +S  S+ S P+ ++  S     S  +  +  +P      V++ +++ +ST
Sbjct: 3146 PTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSST 3205

Query: 776  IKALLELQQTTVKE---KLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELV 832
                  +  +T  E    L S P   T   S  A  +  T    ++P + S         
Sbjct: 3206 TAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS--------- 3256

Query: 833  AEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPAS 892
             E  ++  T EGT +         S P + S P  ++   V+ +  A+  +  + + PA 
Sbjct: 3257 TEASSSPPTAEGTSMP-------TSTPSEGSTPLTSM--PVSTTTVASSETSTLSTTPAD 3307

Query: 893  SPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQ 952
            +   +T   Q + S   A           EG         P T + +  + T   S++  
Sbjct: 3308 TSTPVTTYSQASSSPPIADGTSMPTSTYSEGST-------PLTNMSF--STTPVVSSEAS 3358

Query: 953  KLSQPPLE-QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQ 1011
             LS  P++  T +   T         +   +           +  + +    +   +   
Sbjct: 3359 TLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNT 3418

Query: 1012 AQPKP---------DVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAP 1062
                P           + +  P +A+   LPT       T + ++ + TT       +A 
Sbjct: 3419 LSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVAS--SEAS 3476

Query: 1063 NQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGG 1122
                  V   TP +  S P +S   TA     P  T G   T +T     P + T +   
Sbjct: 3477 TLSTTPVDTSTPVTTSS-PTNSSPTTAEVTSMPTSTAGEGSTPLT---NMPVSTTPVASS 3532

Query: 1123 SSVPKLTSPVTSISPIQASEKTAVSD-ILKMSLMEAQIDTNVEHMIVDPPKKALATSMLT 1181
             +    T+PV S + + +S + + S   L+++ M     +     +       L+++ +T
Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLT---TMLLSSTYVT 3589

Query: 1182 GEAGSLPSTHMV-------VAGMANSTP-QQQKCRESCSSPSTVGSSLTTRKIDPPAV 1231
                S PST  V        +  +NSTP   +      S+PS V + LT   +   +V
Sbjct: 3590 SSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSV 3647



 Score =  106 bits (265), Expect = 1e-22
 Identities = 274/1318 (20%), Positives = 467/1318 (35%), Gaps = 180/1318 (13%)

Query: 76   LTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQ------TAFTVTANAVANAAIQHNAS 129
            +TT     S P ++ + S         MP   P       T+  V+   VA++     ++
Sbjct: 2605 VTTSTETSSSPTTAKDTS---------MPISTPSEVSTSLTSILVSTMPVASSEASTLST 2655

Query: 130  LPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYV 189
             PV   T     +  + T T+S+PT+      S+ T      ++P +N++V    ST  +
Sbjct: 2656 TPVDTRT-----LVTTSTGTSSSPTTAE--GSSMPTSTPGERSTPLTNILV----STTLL 2704

Query: 190  KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249
             +   S     P     T++  ++       P      S  I+ P  GS  +++I+    
Sbjct: 2705 ANSEASTLSTTPVD---TSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSIL---- 2757

Query: 250  NSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPT 309
                  +S + +  ++ ST +T T     I VTTS  +       S S   A VT + PT
Sbjct: 2758 ------VSTLPVASSEASTVST-TAVDTSIPVTTSTEA-------SSSPTTAEVTSM-PT 2802

Query: 310  SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS------VV 363
            S  + T+   P+       + V++S +G+ S+TP      V  +   SS+P+      V 
Sbjct: 2803 STPSETST--PLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVP 2860

Query: 364  MSTVAQGVST-SAIKMASTRLPSPKSLVSAPTQILAQFP----KQHQQSPKQQLYQVQQQ 418
            +ST ++G +  ++I +++T + S ++   + T +    P     +   SP        + 
Sbjct: 2861 ISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPT-----TAEG 2915

Query: 419  TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478
            T   ++ PS VS       +PL   +  T+ +       + T  V        PVT +  
Sbjct: 2916 TSMPISTPSEVS-------TPLTSILVSTVPVAGSEASTLSTTPVDTRT----PVTTSAE 2964

Query: 479  TSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGS 538
             SS SP     ++  I T     TP  + +  T P  S     ++ TP   +   TTS  
Sbjct: 2965 ASS-SPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTE 3023

Query: 539  II--------TVVPKSLATLGGKIISSNIVSGTTTKI------TTIPMTSKPNVIVVQKT 584
                      T +P S  + G   ++S  VS T   I      +T P+ S   V+   + 
Sbjct: 3024 ASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEV 3083

Query: 585  TGKGTTIQG--------------LPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATR-- 628
            +   T  +G              L G  V TT + +    T+ T P      + T+T   
Sbjct: 3084 SSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAH 3143

Query: 629  --PITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQ 686
              P T    + P    S        +P          T +++  +  T  AT V   T  
Sbjct: 3144 SSPTTSEGTSMPTSTPSEGSTPLTYMPVS--------TMLVVSSEDSTLSATPVDTST-P 3194

Query: 687  LVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQD 746
            + T T   +S  AE  +       E     T    S+T  + S         V ++    
Sbjct: 3195 VTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLT 3254

Query: 747  WSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMA 806
             S    A  + PT     + + + S  ST    + +  TTV     S       D S   
Sbjct: 3255 TSTE--ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTS--- 3309

Query: 807  VPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAF---PLLVSHRSQ----P 859
                 T    +S  S S  + +   +     +E +   T ++F   P++ S  S     P
Sbjct: 3310 -----TPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP 3364

Query: 860  QQPSQPQRTLLQHVAQSQTATQTSVVVKSIP------ASSPGAITHIMQQALSSHTAFTK 913
               S P  T  +      TA  TS+   S        AS P + T ++   +++ +    
Sbjct: 3365 VDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPV 3424

Query: 914  HSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQ 973
             S  L T   E     T+   T L   +    S       LS  P+  ++    +     
Sbjct: 3425 DSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVD 3484

Query: 974  TKQKQTIH--LQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQ 1031
            T    T      +     ++  MP         T    E + P  ++  +  P+ + +  
Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMP---------TSTAGEGSTPLTNMPVSTTPVASSEAS 3535

Query: 1032 LPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQ 1091
              TL   P  +   V +       P   Q     ++    +   S  ++  SS   T+S+
Sbjct: 3536 --TLSTTPVDSNTFVTSSSQASSSPATLQVTTM-RMSTPSEGSSSLTTMLLSSTYVTSSE 3592

Query: 1092 VEQPI---ITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSD 1148
               P    + + + VT  T     P     IT   S P   S   +I P+  +  T +S+
Sbjct: 3593 ASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVT-ISE 3651

Query: 1149 ILKMSLMEAQIDTNV--EHMIVDPPKKALATSM--LTGEAGSLPSTHMVVAGMANSTPQQ 1204
                S +     T V     +   P     T+M   T   GS P T M V+    +T   
Sbjct: 3652 AGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVS----TTRVT 3707

Query: 1205 QKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYA 1264
                 + S+PS V S+  T   +  +  AT     +      +       I++   P   
Sbjct: 3708 SSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTR 3767

Query: 1265 IPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS 1322
             P  S+ ++   PS       +TS  +    TA E     +T +GT   P  +++ERS
Sbjct: 3768 FPESSTPSI---PSV------YTSMSMT---TASEGSSSPTTLEGTTTMPMSTTSERS 3813



 Score =  105 bits (262), Expect = 3e-22
 Identities = 247/1190 (20%), Positives = 434/1190 (36%), Gaps = 145/1190 (12%)

Query: 88   SSSEWSIEGRRLVPLMPR--LVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYS 145
            +SS  + EG  +    P     P T+  V+   VAN+     ++ PV + T         
Sbjct: 962  TSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNT--------- 1012

Query: 146  YTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCS-----DEDEK 200
               TTST  S+P P+    ++ +  P+  ++ +  +P  +T+   S + +      +   
Sbjct: 1013 -PLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTST 1071

Query: 201  PRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVK 260
            P       SSSS+      +P +      T    V  S ++    ++   S  P  + + 
Sbjct: 1072 PVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIP 1131

Query: 261  ITFTKPSTQTTNTTTQKVIIVTTSPSSTFVP---------NILSKSHNYAAVTKLVPTSV 311
            +T T     ++ TT +   I T+ PS    P          ++S   N  + T +   + 
Sbjct: 1132 VT-TSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQ 1190

Query: 312  IASTTQKPPVVITASQSSL-VSNSSSGSSSSTPSPIPNTVAVT---AVVSSTPSVVMSTV 367
            +A++T+      TA  +S+  S     S+  T  P+ +T   +   + +S++P    + V
Sbjct: 1191 VATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPV 1250

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQ--QSPK-QQLYQVQQQTQQQVA 424
                 TS+    +     P S  S  + +L   P       SP+   L      T+  V 
Sbjct: 1251 TTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVV 1310

Query: 425  QPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSP 484
              + VS    P +    P    +      + + + T  V  S I    + +T P  +++P
Sbjct: 1311 TSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAI---SILSTTPVDNSTP 1367

Query: 485  IMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVP 544
            +          +T+  ++PT ++ T + P  +PS G    TP  +  V TT      VV 
Sbjct: 1368 VTT--------STEACSSPTTSEGT-SMPNSNPSEG---TTPLTSIPVSTT-----PVVS 1410

Query: 545  KSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLL 604
               +TL    + ++    T+ + T+ P T++   I     +   T ++ +P  N  T + 
Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN--TPVA 1468

Query: 605  NAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKT 664
            N+    T+ T P  +   ++T+T             + S+  PA            +G +
Sbjct: 1469 NSEA-STLSTTPVDSNSPVVTST------------AVSSSPTPA------------EGTS 1503

Query: 665  QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724
              +  P   +   T +   T  + +  +   S      ++ +    +   + T +  +S 
Sbjct: 1504 IAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSM 1563

Query: 725  ESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ 784
            ++S  S+ S P+  +  S     S     + T+P      V++ +++++ST      +  
Sbjct: 1564 QTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTI 1623

Query: 785  TTVKE---KLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERT 841
            +T  E    L S P   T   S  A  +  T    +SP   S  V  S   AE  T+  T
Sbjct: 1624 STPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEG-TSMPT 1682

Query: 842  DEGTEVAFPLL-VSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHI 900
               TE   PL  ++ R+ P   S    TL      + T   TS   +S P +S G     
Sbjct: 1683 STYTEGRTPLTSITVRTTP-VASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGT---S 1738

Query: 901  MQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE 960
            M  +  S       S  + T      E  TL   T +   + +T S  A     S    E
Sbjct: 1739 MPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS-ATPIDTSTPVTTSTEATS---SPTTAE 1794

Query: 961  QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQH 1020
             T +   TL    T       L +  + H L    + S      TP+        P V  
Sbjct: 1795 GTSIPTSTLSEGMTP------LTSTPVSHTLVANSEAST--LSTTPVDSN----SPVVTS 1842

Query: 1021 T---QHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQ-QLPKLQQAPNQPKIYVQPQTPQS 1076
            T     P  A+   + T       T +  + V TT     +       P +   P T  +
Sbjct: 1843 TAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYA 1902

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSV-TKITFEGRQPPTVTKITGGSSVPKLTSPVTSI 1135
            Q+S               P    GSS+ T    EGR P T   +   S+    +S + ++
Sbjct: 1903 QVS-------------SSPTTADGSSMPTSTPREGRPPLTSIPV---STTTVASSEINTL 1946

Query: 1136 SPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLP-STHMVV 1194
            S   A  +T V+   + S       T  +   +  P  +  ++ LT    S+P ST +VV
Sbjct: 1947 STTLADTRTPVTTYSQAS----SSPTTADGTSMPTPAYSEGSTPLT----SMPLSTTLVV 1998

Query: 1195 AGMAN---------STPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATG 1235
            +  A+         STP       S S  +  G+S+ T        P  G
Sbjct: 1999 SSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAG 2048



 Score =  105 bits (262), Expect = 3e-22
 Identities = 251/1225 (20%), Positives = 448/1225 (36%), Gaps = 142/1225 (11%)

Query: 108  PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTS-TPVPSGSIATV 166
            P T   V+   VA++  + +     PA+T S  V  YS  S++ST    T +P+ + +  
Sbjct: 1043 PLTRMPVSTTMVASS--ETSTLSTTPADT-STPVTTYSQASSSSTTADGTSMPTSTYSEG 1099

Query: 167  KSPRPASPASNVVVLPSGSTVYVKS-------VSCSDEDEKPRKRRRTNSSSSSPVVLKE 219
             +P  + P S  +V+ S ++    +       V+ S E           S  +SP     
Sbjct: 1100 STPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGT 1159

Query: 220  VPKAVVPVSKTI----------TVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQ 269
             P A +PVS T+          T PV    +++   +  A+S PP      +  + P  +
Sbjct: 1160 TPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE--ASSPPPTAEVTSMPTSTPGER 1217

Query: 270  TTNTTTQKV----------IIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKP 319
            +T  T+  V            ++TSP  T  P + + +   ++ T    TS+  STT + 
Sbjct: 1218 STPLTSMPVRHTPVASSEASTLSTSPVDTSTP-VTTSAETSSSPTTAEGTSLPTSTTSEG 1276

Query: 320  PVVITAS--QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIK 377
              ++T+    ++LV++  + +  +TP      V  +  VSS+P+    T     + S  +
Sbjct: 1277 STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGR 1336

Query: 378  MASTRLPSPKSLV-SAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQ-VAQPSPVSHQQQP 435
               T +P   +LV S+   IL+  P  +              T  +  + P+    +   
Sbjct: 1337 TPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTT 1396

Query: 436  QQSPLPPGIKPTIQIKQES----GVKIITQQVQPSKILPKPVTA---TLPTSSNS----P 484
              + +P    P +  +  +     V   T     ++    P TA   ++PTS+ S    P
Sbjct: 1397 PLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTP 1456

Query: 485  IMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGS----II 540
            +  +  +   +     +T + T      P V+ +    + TP   T +  ++ S     +
Sbjct: 1457 LKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTAL 1516

Query: 541  TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQ-------- 592
            T +P S  T+    I+S     TT  +T+ P+T+         TT  GT++Q        
Sbjct: 1517 TSIPVSTTTVASSEINS---LSTTPAVTSTPVTTYSQASS-SPTTADGTSMQTSTYSEGS 1572

Query: 593  -GLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651
              L    V T L+ +    T+ T P  +K  +  +T   +    T  +G   T+   ++ 
Sbjct: 1573 TPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSS---TTAEGSSMTISTPSEG 1629

Query: 652  IPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGN---SSIQE 708
             P  ++      T  +  P+  T   T V   +  + +  +  +   AE  +   S+  E
Sbjct: 1630 SP--LLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTE 1687

Query: 709  GKEEPQNYT------DSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIY 762
            G+    + T       SS+ ST S+    +S PV     +R    +    +M  S     
Sbjct: 1688 GRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNS----- 1742

Query: 763  QDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESP 822
                  + S  +T    + +  T V     S      ID S    P+  + E   SP + 
Sbjct: 1743 ------TPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTS---TPVTTSTEATSSPTTA 1793

Query: 823  SIAVVESELVAEYIT--TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTAT 880
                + +  ++E +T  T      T VA     +  + P   + P  T    V+ S T  
Sbjct: 1794 EGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTA-VSSSPTPA 1852

Query: 881  QTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYR 940
            + + +  S P+    A+T I    +S+ T  +  +  L T         T   Q      
Sbjct: 1853 EGTSIATSTPSEGSTALTSI---PVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPT 1909

Query: 941  SALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQ----------TKQKQTIHLQADQLQHK 990
            +A   S      +  +PPL    +   T+   +          T+   T + QA      
Sbjct: 1910 TADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQAS----- 1964

Query: 991  LPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQ----LPTLMAQPPQTVVQV 1046
                P  +      TP   E + P   +  +   +V+ +       P   + P  T  + 
Sbjct: 1965 --SSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEG 2022

Query: 1047 LAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTK- 1105
             +  TT     +Q +    +       P S  +L  SSE  T S       TQ ++ T+ 
Sbjct: 2023 SSSPTTAGGTSIQTSTPSERTTPLAGMPVS-TTLVVSSEGNTLSTTPVDSKTQVTNSTEA 2081

Query: 1106 ---ITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTN 1162
                T EG    T++  + GS  P LTS   S +P+ + E + +S     S       T 
Sbjct: 2082 SSSATAEG-SSMTISAPSEGS--PLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTE 2138

Query: 1163 VEHMIVDPPKKALATSMLTGE---AGSLPSTHMVVAGMA----------NSTPQQQKCRE 1209
            V    +     ++ TS  +       S+P +  VVA  A           STP       
Sbjct: 2139 VSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198

Query: 1210 SCSSPSTVGSSLTTRKIDPPAVPAT 1234
              S  ++ G+S+ T      + P T
Sbjct: 2199 RSSPTTSEGTSMPTSTPSEGSTPFT 2223



 Score =  101 bits (252), Expect = 4e-21
 Identities = 257/1251 (20%), Positives = 446/1251 (35%), Gaps = 162/1251 (12%)

Query: 83   MSGPNSSSEWSIEGRRLVPLMPR--LVPQTAFTVTANAVANAAIQHNASLPVPAETGSKE 140
            +S   SSS  + EG  L    P     P T   ++   V ++  + +     PA T    
Sbjct: 249  ISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSS--EASTLSTTPAATNIPV 306

Query: 141  VVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSG-STVYVKSVSCS---- 195
            +     +S+ +T   T +P+ +     +P  ++PAS + V  S  ST+ +  V  S    
Sbjct: 307  ITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVT 366

Query: 196  ---DEDEKPRKRRRTN------SSSSSPVVLKEVPKAVV---PVSKTITVPVSGSPKMSN 243
               +    P     T+      S  S+P+    V   +V     S T T+PV     ++ 
Sbjct: 367  TSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTT 426

Query: 244  IMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAV 303
               S A+S P       I  + PS  +T  T+     V+T+P ++      S++ N +  
Sbjct: 427  --ASEASSSPTTAEDTSIATSTPSEGSTPLTSMP---VSTTPVAS------SEASNLSTT 475

Query: 304  TKLVPTSVIAST--TQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS 361
                 T V  ST  +  PP   TA  +S+ +++ S  S+   S   +T+ V +  +ST S
Sbjct: 476  PVDSKTQVTTSTEASSSPP---TAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLS 532

Query: 362  VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421
                  +  V+TS+   +S+  P   S+   PT   ++        P      V  +   
Sbjct: 533  TTPVDTSTPVTTSSEASSSSTTPEGTSI---PTSTPSEGSTPLTNMPVSTRLVVSSEAST 589

Query: 422  QVAQPSP-----VSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT-- 474
                P+       +  +    S    G         E G  I +  V  + +     +  
Sbjct: 590  TSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTL 649

Query: 475  ATLPTSSNSPIMVVSSNGAIMTTKLVTT-PTGTQATYTRPTVSPSIGRMAATPGAATYVK 533
            +T P  SN+P+   +   +  TT   T+ PT T    + P  S  +         A+ + 
Sbjct: 650  STTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLS 709

Query: 534  TTSGSIITVVPKSLATLGGKIISSNIVSGTTTKIT-TIPMTSKPNVIVVQKTTGKGTTIQ 592
            TT     T V  S         +      T+T    + P+TS P V     T+ + +T+ 
Sbjct: 710  TTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP-VSKTLLTSSEASTLS 768

Query: 593  GLP--GKNVVTTLLNAG-----GEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTV 645
              P      +TT   A       E T   + T ++ + L  + P++   VT P+    + 
Sbjct: 769  TTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLST 828

Query: 646  QPAAKIIPTKIVYGQQGKTQVLIKPKP---VTFQATVVSE----------QTRQLVTETL 692
             P     P          T+V   P P    +   +  SE           T  + T  +
Sbjct: 829  TPVDSNSPVTT------STEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAI 882

Query: 693  QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVH-------VIASRRQ 745
               S      ++ +    E   + T S  +S  +S   + S P+         V++S  +
Sbjct: 883  STLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEAR 942

Query: 746  DWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQM 805
              S   +   T  T   +  SS + +  ++I      + TT    L S P   T+  +  
Sbjct: 943  TLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTT---PLTSTPVSHTLVANSE 999

Query: 806  AVPIQMTQEKRHSPESPSIAVVESELVAE--YITTERTDEG-----------TEVAFPLL 852
            A  +  T    ++P + S         AE   + T    EG           T VA    
Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET 1059

Query: 853  VSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVK-----SIPASSPGAITHIMQQALSS 907
             +  + P   S P  T  Q  + S TA  TS+        S P +S    T ++  + +S
Sbjct: 1060 STLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119

Query: 908  H------------TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQ----SAKQ 951
                         T  T+ S    T EG    + T  P  G    +++  S     S++ 
Sbjct: 1120 TLSTTPVDTSIPVTTSTEASSSPTTAEG--TSIPTSPPSEGTTPLASMPVSTTLVVSSEA 1177

Query: 952  QKLSQPPLE-QTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQE 1010
              LS  P++ +TQ+   T         +   +       +   +  + +RH  +   +  
Sbjct: 1178 NTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEAS 1237

Query: 1011 QAQPKP---------DVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQA 1061
                 P           + +  P  A+   LPT       T++  + V TT     L  +
Sbjct: 1238 TLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTT-----LVTS 1292

Query: 1062 PNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITF-EGRQP----PTV 1116
            P    +   P   +     P  +  + +S    P   +G+S+   T+ EGR P    P  
Sbjct: 1293 PEASTLLTTPVDTKG----PVVTSNEVSS---SPTPAEGTSMPTSTYSEGRTPLTSIPVN 1345

Query: 1117 TKITGGSSVPKL-TSPVTSISPIQASEKTAVSDILK--MSLMEAQIDTNVEHMIVDPPKK 1173
            T +   S++  L T+PV + +P+  S +   S       S+  +        +   P   
Sbjct: 1346 TTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIP--- 1402

Query: 1174 ALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTV-GSSLTT 1223
               T +++ EA +L +T      +  STP      E+ SSP+T  G S+ T
Sbjct: 1403 VSTTPVVSSEASTLSAT-----PVDTSTPGTTSA-EATSSPTTAEGISIPT 1447



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 234/1181 (19%), Positives = 412/1181 (34%), Gaps = 144/1181 (12%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
            T+T +T T+   P   ++   +P   S  S+V    +  T  V S   +  + +      
Sbjct: 67   TATGTTSTNVVEPRMYLSCSTNPEMTSIESSV----TSDTPGVSSTRMTPTESRTTSEST 122

Query: 207  TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANS-LPPHMSPVKITFTK 265
            ++S++  P   ++      P    + +       +S+ M  ++ + LP   +   +T+ K
Sbjct: 123  SDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTY-K 181

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325
                T  TT+ +     T+P ST +P    KS N    T L  TS+ AST +        
Sbjct: 182  VDMSTPLTTSTQASSSPTTPESTTIP----KSTNSEGSTPL--TSMPASTMK-------- 227

Query: 326  SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP- 384
                 V++S + +  +TP  I   V ++A  SS+P+          + S      TR+P 
Sbjct: 228  -----VASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPL 282

Query: 385  SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGI 444
            S   +VS+    L+  P                      A   PV    +   SP     
Sbjct: 283  SVMLVVSSEASTLSTTP---------------------AATNIPVITSTEASSSP----- 316

Query: 445  KPTIQIKQESGVKIITQ-QVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTP 503
                      G  I T    + S  L     +T+P +++   M   S   + T+ LVTT 
Sbjct: 317  ------TTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSE--MSTLSITPVDTSTLVTTS 368

Query: 504  TGTQATYTRPTVSPSIGRMAAT-PGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562
            T   +    PT + +   + +T    +T +     S I V     +T     + S     
Sbjct: 369  TEPSSL---PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVT 425

Query: 563  TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPA 622
            T ++ ++ P T++   I     +   T +  +P   V TT + +     + T P  +K  
Sbjct: 426  TASEASSSPTTAEDTSIATSTPSEGSTPLTSMP---VSTTPVASSEASNLSTTPVDSKTQ 482

Query: 623  ILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSE 682
            + T+T               S+  P A++         +G T +           T +S 
Sbjct: 483  VTTSTE-------------ASSSPPTAEVNSMPTSTPSEGSTPL-----------TSMSV 518

Query: 683  QTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIAS 742
             T  + +      S      ++ +    E   + T    +S  +S  S+ S P+ ++  S
Sbjct: 519  STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVS 578

Query: 743  RRQDWSEHEIAMETSP--TIIYQDVSSESQSATSTIKALLELQQTTVKEK---LESKPRQ 797
             R   S       T+P  +  +   SSE+ S+++T +    +  +T  E+   + S    
Sbjct: 579  TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEG-TSMPTSTYSERGTTITSMSVS 637

Query: 798  PTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRS 857
             T+  S  A  +  T    ++P + S     S   AE  T+  T   TE + PL     +
Sbjct: 638  TTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG-TSMPTSTYTEGSTPLTSMPVN 696

Query: 858  QPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAI--THIMQQALSSHTAFTKHS 915
                 S    TL      + T   TS    S P ++ GA   T    +  +  T+     
Sbjct: 697  TTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSK 756

Query: 916  EELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQ---QKLSQPPLEQTQLQVKTLQCF 972
              L + E        LD  T +   +  + S +  +     +S P      L    +   
Sbjct: 757  TLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSIT 816

Query: 973  QTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQL 1032
                 +   L    +    P      +     TP  +  + P       + P+ +     
Sbjct: 817  PVTSPEASTLSTTPVDSNSPVTTSTEVSSSP-TP-AEGTSMPTSTYSEGRTPLTSMPVS- 873

Query: 1033 PTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQ--------MSLPASS 1084
             TL+A    + +    V T+  +    +A + P        P S          S+P S+
Sbjct: 874  TTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDST 933

Query: 1085 EKQTASQVEQPIITQGSSVTKIT--FEGRQPPTVTKITGGSSVPKLTSPVTSISPIQAS- 1141
                +S+      T   + T +T   E    PT  +   G+S+P  T P    +P+ ++ 
Sbjct: 934  TPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAE---GTSIPTST-PSEGTTPLTSTP 989

Query: 1142 -EKTAVSDILKMSLMEAQIDTN----VEHMIVDPPKKALATSMLTG--EAGSLPSTHMVV 1194
               T V++    +L    +D+N           PP  A  TSM T     GS P T M V
Sbjct: 990  VSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPV 1049

Query: 1195 AGMA---------------NSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMR 1239
            +                   STP     + S SS +  G+S+ T      + P T   + 
Sbjct: 1050 STTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVS 1109

Query: 1240 IQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGL 1280
             + V   +A       +  +IP       SSS    E + +
Sbjct: 1110 TRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSI 1150



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 166/801 (20%), Positives = 301/801 (37%), Gaps = 82/801 (10%)

Query: 145  SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204
            S  STT   TSTPV + + A++ SP  A   S     PS  T  + S+  S     P   
Sbjct: 3358 STLSTTPVDTSTPVTTSTEASL-SPTTAEGTSIPTSSPSEGTTPLASMPVSTT---PVVS 3413

Query: 205  RRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGS-PKMSNIMQSIANSLPPHMSPVKITF 263
               N+ S++PV    +       S + T+    S P  +    S   S+ P +S   +  
Sbjct: 3414 SEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMP-LSTTPVAS 3472

Query: 264  TKPSTQTTNTTTQKVIIVTTSP--SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPV 321
            ++ ST +T        + T+SP  SS     + S   + A       T++  STT     
Sbjct: 3473 SEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASS 3532

Query: 322  VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381
              +   ++ V +++  +SSS  S  P T+ VT +  STPS   S++   + +S    +S 
Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSE 3592

Query: 382  RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLP 441
                    V   T +          +P + +  +   T  +V+ P  +        +   
Sbjct: 3593 ASTPSTPSVDRSTPVTTSTQSNSTPTPPEVI-TLPMSTPSEVSTPLTIMPVSTTSVTISE 3651

Query: 442  PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATL--PTSSNSPIMVVSSNGAIMTTKL 499
             G   T+ +   + V I + QV  S + P+  T  +  P+  ++P+  +     + TT++
Sbjct: 3652 AGTASTLPVDTSTPV-ITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMP----VSTTRV 3706

Query: 500  VTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNI 559
             ++   T +T +  T +P      A   +AT   TT       +P  ++TLG  I+ S  
Sbjct: 3707 TSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMS---VSMPMEISTLGTTILVS-- 3761

Query: 560  VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGA 619
                TT +T  P +S P++  V  +    T  +G    +  TTL    G  T+    T  
Sbjct: 3762 ----TTPVTRFPESSTPSIPSVYTSMSMTTASEG---SSSPTTL---EGTTTMPMSTTSE 3811

Query: 620  KPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATV 679
            +  +LT T  I+ + V  P    +   P        +   + G     I  +  T + ++
Sbjct: 3812 RSTLLT-TVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFS--IPAEVTTIRISI 3868

Query: 680  VSEQ----TRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST-------ESSQ 728
             SE+    T  LV+ TL  +   A   ++   +        TD++S+ T         S 
Sbjct: 3869 TSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSV 3928

Query: 729  SSQDSQPVVHV------IASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLEL 782
             ++ S P   +      + S   D         ++P I   ++++ S S++ST  +    
Sbjct: 3929 ITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT 3988

Query: 783  QQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTD 842
            ++ T      + P   T      A     T  +  +  + +++   +   +  +TT    
Sbjct: 3989 KEFTTPAMTTAAPL--TYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVT 4046

Query: 843  EGTEVAFP-LLVSHRSQPQQP----------------------------SQPQRTLLQHV 873
              +E + P  + SH   P  P                            ++P        
Sbjct: 4047 PSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFP 4106

Query: 874  AQSQTATQTSVVVKSIPASSP 894
              + TA  T+  +KS P S+P
Sbjct: 4107 TVTTTAVPTNTTIKSNPTSTP 4127



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 233/1146 (20%), Positives = 418/1146 (36%), Gaps = 153/1146 (13%)

Query: 95   EGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPT 154
            EG  L+  +P      A +  A+ ++   +  N+ +    E  S        +  TST T
Sbjct: 1628 EGSPLLTSIPVSTTPVA-SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYT 1686

Query: 155  STPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSP 214
                P  SI    +P  +S  S +   P  ++  V   + ++    P     T+  +S+P
Sbjct: 1687 EGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPV--TTSTEARSSPTTSEGTSMPNSTP 1744

Query: 215  VVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTT 274
                   +   P++   ++PVS +P +S+   +++ +     +PV    T  +  T++ T
Sbjct: 1745 ------SEGTTPLT---SIPVSTTPVLSSEASTLSATPIDTSTPV----TTSTEATSSPT 1791

Query: 275  TQKVIIVTTSPSSTFVPNILSK--SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVS 332
            T +   + TS  S  +  + S   SH   A ++    S     +  P V  TA  SS   
Sbjct: 1792 TAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSS--P 1849

Query: 333  NSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSA 392
              + G+S +T +P   + A+T++  ST +V  S      +T A+   ST + +   + S+
Sbjct: 1850 TPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAV--TSTPVTTYAQVSSS 1907

Query: 393  PTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQ 452
            PT                        T    + P+    + +P  + +P           
Sbjct: 1908 PT------------------------TADGSSMPTSTPREGRPPLTSIP----------- 1932

Query: 453  ESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTR 512
                 + T  V  S+I      +T    + +P+   S       +   TT  GT    + 
Sbjct: 1933 -----VSTTTVASSEI---NTLSTTLADTRTPVTTYS-----QASSSPTTADGT----SM 1975

Query: 513  PTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPM 572
            PT + S G   +TP  +  + TT      VV    +TL    + ++  + T+T+ ++ P 
Sbjct: 1976 PTPAYSEG---STPLTSMPLSTT-----LVVSSEASTLSTTPVDTSTPATTSTEGSSSPT 2027

Query: 573  TSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITK 632
            T+    I     + + T + G+P   V TTL+ +    T+ T P  +K  +  +T   + 
Sbjct: 2028 TAGGTSIQTSTPSERTTPLAGMP---VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSS 2084

Query: 633  MIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETL 692
                     GS++  +A    + ++      T  +  P+  T   T V +    ++T T 
Sbjct: 2085 ATAE-----GSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPV-DSNSPVITSTE 2138

Query: 693  QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEI 752
              +S +   G S       +   Y+D  +  T        S PV   + +     S    
Sbjct: 2139 VSSSPIPTEGTSM------QTSTYSDRRTPLT--------SMPVSTTVVA-----SSAIS 2179

Query: 753  AMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMT 812
             + T+P     D S+   ++T    +    + T++     S+   P   +    +P+ +T
Sbjct: 2180 TLSTTPV----DTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPV-VT 2234

Query: 813  QEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQH 872
             E      +P           E  ++  T EGT +    L S  + P        TL   
Sbjct: 2235 SEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTL-SEGTTPLTSIPVSHTL--- 2290

Query: 873  VAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLD 932
            VA S+ +T     + + P  S    T   + +    TA         + EG      T  
Sbjct: 2291 VANSEVST-----LSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL--TRM 2343

Query: 933  PQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLP 992
            P +     S  T + S      S P    +Q          T    + + +       +P
Sbjct: 2344 PVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVP 2403

Query: 993  --QMPQLSIRHQKLTPLQQEQAQP-KPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAV 1049
               MP +S      +    + + P     + +  P  A+   +PT       T +  + V
Sbjct: 2404 VSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV 2463

Query: 1050 KTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFE 1109
             TT  +    +A       V   TP +  S  ASS   TA  +  PI T     T +T  
Sbjct: 2464 STTPVVS--SEAGTLSTTPVDTSTPMT-TSTEASSSPTTAEDIVVPISTASEGSTLLT-- 2518

Query: 1110 GRQPPTVTKITGGSSVPKLTSPVTSISPIQ-----ASEKTAVSDILKMSLMEAQIDTNVE 1164
               P + T +    +    T+PV S SP+      +S  T+       +   ++  T + 
Sbjct: 2519 -SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR 2577

Query: 1165 HMIVDPPKKALATSMLTGEAGSLPST------HMVVAGMANSTPQQQK-CRESCSSPSTV 1217
             M V    K LA+S    EA +L +T       +  +   +S+P   K      S+PS V
Sbjct: 2578 SMPVS--TKPLASS----EASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEV 2631

Query: 1218 GSSLTT 1223
             +SLT+
Sbjct: 2632 STSLTS 2637



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 173/786 (22%), Positives = 289/786 (36%), Gaps = 101/786 (12%)

Query: 78   TIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETG 137
            TIA   S P S++        ++PL    V  +  +  +    + +     S P  +   
Sbjct: 3441 TIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPT 3500

Query: 138  SKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDE 197
            + EV   S  ++T+   STP+ +  ++T  +P  +S AS +   P  S  +V S S +  
Sbjct: 3501 TAEVT--SMPTSTAGEGSTPLTNMPVST--TPVASSEASTLSTTPVDSNTFVTSSSQASS 3556

Query: 198  D----EKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVP---VSGSPKMSNIMQSIAN 250
                 +    R  T S  SS +    +    V  S+  T     V  S  ++   QS + 
Sbjct: 3557 SPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNST 3616

Query: 251  SLPPHM--------SPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAA 302
              PP +        S V    T     TT+ T  +    +T P  T  P I S   + + 
Sbjct: 3617 PTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSP 3676

Query: 303  VTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSV 362
            VT    T  I + ++    + T   S+    SS GS+ STPS + +T   T+  + + S 
Sbjct: 3677 VTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSA 3736

Query: 363  VMSTVAQGVST--------SAIKMAS---TRLP--SPKSLVSAPTQILAQFPKQHQQSP- 408
             + +    VS         + I +++   TR P  S  S+ S  T +      +   SP 
Sbjct: 3737 TLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPT 3796

Query: 409  -------KQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPL--PPGIKPTIQI--------- 450
                          ++ T       SP+S     + S L  PPG   T  +         
Sbjct: 3797 TLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFS 3856

Query: 451  --KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQA 508
               + + ++I     + + +    V+ TLPTS   P   ++S   + T+   T  T T +
Sbjct: 3857 IPAEVTTIRISITSERSTPLTTLLVSTTLPTS--FPGASIASTPPLDTSTTFTPSTDTAS 3914

Query: 509  TYTRP---TVSPSIGRMAATPGAATYVKTT--SGSIITVVPKSLATLGGKIISSNIVS-- 561
            T T P   T+S S+    +TPG   ++ +T  + S   V P +   +   +I+S  ++  
Sbjct: 3915 TPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTP 3974

Query: 562  -----------GTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNA-GGE 609
                        TT + TT  MT+   +  V  +T   T      G     + L+A    
Sbjct: 3975 STSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTP 4034

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIK 669
             T  +V T        ++RP T    T P     T  PA    P          +   + 
Sbjct: 4035 HTSTSVTTRPVTPSSESSRPSTITSHTIP----PTFPPAHSSTPP-----TTSASSTTVN 4085

Query: 670  PKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQS 729
            P+ VT   T     TR   T +    +  A   N++I   K  P +      ++T     
Sbjct: 4086 PEAVTTMTTRTKPSTR---TTSFPTVTTTAVPTNTTI---KSNPTSTPTVPRTTTCFGDG 4139

Query: 730  SQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA-----TSTIKALLELQQ 784
             Q++       ASR ++    +      P + Y ++  E  S+       TI A +EL  
Sbjct: 4140 CQNT-------ASRCKNGGTWDGLKCQCPNLYYGELCEEVVSSIDIGPPETISAQMELTV 4192

Query: 785  TTVKEK 790
            T    K
Sbjct: 4193 TVTSVK 4198



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 213/1033 (20%), Positives = 364/1033 (35%), Gaps = 122/1033 (11%)

Query: 76   LTTIAHNMSGPNSSSEWSI------EGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNAS 129
            +TT     S P +S   S+      EG   +  MP     T   V++     +A   + S
Sbjct: 3136 VTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP---VSTMLVVSSEDSTLSATPVDTS 3192

Query: 130  LPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYV 189
             PV   T S E    +    TS PTSTP          +P  + P SN  V  S +++  
Sbjct: 3193 TPV---TTSTEATSSTTAEGTSIPTSTPSEG------MTPLTSVPVSNTPVASSEASI-- 3241

Query: 190  KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249
              +S +  D        T +SSS        P      S   + P  GS  ++++  S  
Sbjct: 3242 --LSTTPVDSNTPLTTSTEASSS--------PPTAEGTSMPTSTPSEGSTPLTSMPVSTT 3291

Query: 250  NSLPPHMSPVKITFTKPSTQTTN----TTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK 305
                   S +  T    ST  T     +++  +   T+ P+ST+       ++   + T 
Sbjct: 3292 TVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTP 3351

Query: 306  LVPTSVIASTTQKPPV-----VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP 360
            +V +   AST    PV     V T++++SL   ++ G+S  T SP   T  + ++  ST 
Sbjct: 3352 VVSSE--ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTT 3409

Query: 361  SVVMSTV----AQGVSTSAIKMASTRLPSPKSL---VSAPTQILAQFPKQHQQSPKQQLY 413
             VV S V       V ++ +   ST   S  ++    S PT   ++        P     
Sbjct: 3410 PVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTP 3469

Query: 414  QVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV 473
                +       P   S    P  +  P    PT    + + +   T     + +   PV
Sbjct: 3470 VASSEASTLSTTPVDTS---TPVTTSSPTNSSPT--TAEVTSMPTSTAGEGSTPLTNMPV 3524

Query: 474  TATLPTSSNSPIM---VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPG--A 528
            + T   SS +  +    V SN  + ++   ++   T    T    +PS G  + T    +
Sbjct: 3525 STTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLS 3584

Query: 529  ATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKG 588
            +TYV ++  S  +      +T       SN  + T  ++ T+PM++   V          
Sbjct: 3585 STYVTSSEASTPSTPSVDRSTPVTTSTQSN-STPTPPEVITLPMSTPSEV---------S 3634

Query: 589  TTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATR----PITKMIVTQP---KGI 641
            T +  +P      T+  AG   T  T+P      ++T+T+    P+T    T P      
Sbjct: 3635 TPLTIMPVSTTSVTISEAG---TASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSE 3691

Query: 642  GSTVQPAAKIIPTKIV--YGQQGKTQVLIKPKPVTFQATVVSEQ-TRQLVTETLQQASRV 698
            GST      +  T++    G    T  ++   PVT     +S   T    T ++     +
Sbjct: 3692 GSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEI 3751

Query: 699  AEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIAS--RRQDWSEHEIAMET 756
            +  G + +            S++  T   +SS  S P V+   S     + S     +E 
Sbjct: 3752 STLGTTILV-----------STTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEG 3800

Query: 757  SPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKR 816
            + T+     S  S   T+ + + + +   +    L + P   +  L        +T  K 
Sbjct: 3801 TTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPL--------LTSTKA 3852

Query: 817  HSPESPSIAVVESELVAEYITTERTDEGTE--VAFPLLVSHRSQPQQPSQPQRTLLQHVA 874
             S   P+    E   +   IT+ER+   T   V+  L  S        + P  T      
Sbjct: 3853 GSFSIPA----EVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTP 3908

Query: 875  QSQTATQTSVVVKS-------IPASSPGAITHIMQQALSSHTA--FTKHSEELGTEEGEV 925
             + TA+  ++ V +          S+PG    I    ++S TA  F   +  + T     
Sbjct: 3909 STDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITS 3968

Query: 926  EEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQAD 985
             E++T    +     S  T  +       +  PL  T + + T         +     A 
Sbjct: 3969 TELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPL--TYVTMSTAPSTPRTTSRGCTTSAS 4026

Query: 986  QLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMV--AKDRQLPTLMAQPPQTV 1043
             L          S+  + +TP   E ++P     HT  P    A     PT  A      
Sbjct: 4027 TLSATSTPHTSTSVTTRPVTP-SSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVN 4085

Query: 1044 VQVLAVKTTQQLP 1056
             + +   TT+  P
Sbjct: 4086 PEAVTTMTTRTKP 4098


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 257/1293 (19%), Positives = 470/1293 (36%), Gaps = 186/1293 (14%)

Query: 53    SKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAF 112
             S+V S  T+R+       ++     TIA  ++ P + +  +I    + P + RLV     
Sbjct: 10739 SQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVT 10798

Query: 113   TVTA-NAVANAAIQHNASLPV--------PAETG------------SKEVVCYSYTSTTS 151
             ++ A  +  N A+ ++   P         PA+T             SK     S T++  
Sbjct: 10799 SLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHG 10858

Query: 152   TPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSS 211
               +S+ VP+ +++T + P   +P          +T+ + ++S  + +  P         +
Sbjct: 10859 AESSSAVPTPTVST-EVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEA 10917

Query: 212   SS----PVVLKEVPKAV---VPVSKTI---TVPV--------SGSPKMSNIMQSIANSLP 253
             SS    P V   VP  V   V  S+ +   T+P+          +P M+    + A S  
Sbjct: 10918 SSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAV 10977

Query: 254   PHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIA 313
             P + P       P   T+   + + +  TT P+ T  P     + + A       +S + 
Sbjct: 10978 PTVLP-----EVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVP 11032

Query: 314   STTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQG--- 370
             + + + P V+T    SLV++SS  +S+S    IP  +     + +TPS+  S  A+    
Sbjct: 11033 TVSPEVPGVVT----SLVTSSSGVNSTS----IPTLILSPGELETTPSMATSHGAEASSA 11084

Query: 371   -----VSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQ 425
                  VS     + +  + S +++ S    IL     + + +P          T   V  
Sbjct: 11085 VPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTP-------SMATSHGVEA 11137

Query: 426   PSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS----- 480
              S V        SP  PG+  ++     +        +  S   P+  T+ +  S     
Sbjct: 11138 SSAVL-----TVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMI 11192

Query: 481   SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPS----IGRMAATPGAATYVKTTS 536
             S  P + VS     + T LVT+     + ++  TV+ S    I    A PG        +
Sbjct: 11193 SAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPT 11252

Query: 537   GSIITVVP-KSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIV---VQKTTGKGTTIQ 592
              ++ T  P  +++ +     SS+ +  TT++ +   + + P+ +     + ++   TTI 
Sbjct: 11253 LTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTIS 11312

Query: 593   -GLPGKNVVTTLLNAGG---EKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPA 648
              G+PG  V+T+L+ + G     T  TVP     +  TA+       VT P  + ST  P 
Sbjct: 11313 PGIPG--VLTSLVTSSGRDISATFPTVPESPHESEATAS------WVTHP-AVTSTTVPR 11363

Query: 649   AKIIPTKIVYGQQGKTQVLIKPKP-----VTFQATVVSEQTRQLVTETLQQASRVAEAGN 703
                  T      +  T   I   P       F    VS     +VT  +  +        
Sbjct: 11364 T----TPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITI 11419

Query: 704   SSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQ 763
              ++     EP+  T   S  T S   +  + P + V     +  +   I+  T  T  + 
Sbjct: 11420 PTLTLSSGEPETTT---SFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFP 11476

Query: 764   DVS-SESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQ---EKRHSP 819
              ++ +  +  T+ I+ +   +  T+  +   K      D +   +P+ +T    E   + 
Sbjct: 11477 TLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTT---LPVAITSPGPEASSAV 11533

Query: 820   ESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTA 879
              + +I+   S+LV   + +  TD  T   FP L     +P+  +    T L H A++ T 
Sbjct: 11534 STTTISPDMSDLVTSLVPSSGTD--TSTTFPTLSETPYEPETTA----TWLTHPAETSTT 11587

Query: 880   --------------------------TQTSVVVKSIPASSPGAIT-HIMQQALSSHTAFT 912
                                       T++ V   +IP S PG +T  +   A  + TA  
Sbjct: 11588 VSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIP 11647

Query: 913   KHSEELGTEEGEVEEMDTLDPQTGLF--YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQ 970
               +   G  E           QTG     R+  +         ++ PP   T +  +T  
Sbjct: 11648 TLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVS-RTTS 11706

Query: 971   CFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDR 1030
              F         + A          P+       LT +      P+           A   
Sbjct: 11707 SFSHSSPDATPVMATS--------PRTEASSAVLTTI--SPGAPEMVTSQITSSGAATST 11756

Query: 1031  QLPTLMAQP--PQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088
              +PTL   P  P+T     A+ +T   P+ + +   P   V PQ  ++  SL      +T
Sbjct: 11757 TVPTLTHSPGMPETT----ALLSTH--PRTETSKTFPASTVFPQVSETTASLTIRPGAET 11810

Query: 1089  ASQVEQPIITQGSSVTKI---TFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTA 1145
             ++ +  P  T  S  T +   T      PT +      + P  T P T  S +  +   +
Sbjct: 11811 STAL--PTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLS 11868

Query: 1146  VSDILKMSLM----EAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANST 1201
             +  +    L+     A+  T+   + V P    L+++ +T +    P T  V +    ++
Sbjct: 11869 LGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDK---PQT--VTSWNTETS 11923

Query: 1202  PQQQKCRESCSSPSTVGSSLTTRKIDPPAVPAT 1234
             P          S +  G+++T    + P  P T
Sbjct: 11924 PSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKT 11956



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 263/1312 (20%), Positives = 485/1312 (36%), Gaps = 186/1312 (14%)

Query: 88   SSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYT 147
            SSS  SI+G       P + P T+          A +  +    +  +TG         T
Sbjct: 6405 SSSRTSIQGTE----KPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRA-----T 6455

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            S  +    T + +    T  +        ++  L S    Y+   S       P    +T
Sbjct: 6456 SQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTS-------PPSVEKT 6508

Query: 208  NSSSSS---PVVLKEVP-KAVVPVSKT------ITVPVSGSPKMSNIMQSIANSLPPHMS 257
            +SSSS    P +    P    +P S+        ++P SG  K ++++ S+A SLPP++ 
Sbjct: 6509 SSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVA-SLPPNLG 6567

Query: 258  PVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQ 317
                    P+T      T+K+   +T+ + T V    S+  +Y++V        + S   
Sbjct: 6568 STSHKI--PTTSEDIKDTEKMY-PSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTS--- 6621

Query: 318  KPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVT-----------AVVSSTPSVVMST 366
             P V     + ++VS S  GSS  T   + +T ++             +VS+  S V+  
Sbjct: 6622 -PMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHK 6680

Query: 367  VAQGVS-TSAIKMASTR---LPSPKSLVSAP---TQILAQFPKQ---------------- 403
            +  G + TS  ++AS+R   +P P     +P   T+++   P                  
Sbjct: 6681 LTTGATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTG 6740

Query: 404  -HQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQS--------------PLPPGIKPTI 448
                S  Q  + +   T    A    ++ Q+ P                  +PP I+ T 
Sbjct: 6741 PPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTS 6800

Query: 449  QIKQESGVKIITQQVQPSKILPKP-VTATLPTSSN---SPIMVVSSNGAIMTTK-LVTTP 503
                       +  + PS  +  P V++TLP + +   SP+  + +   +MTT  L T+P
Sbjct: 6801 ----------FSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSP 6850

Query: 504  TGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGT 563
              T  T + P +S +   +  T    T ++    S  T       T  G    S++++ +
Sbjct: 6851 EPT--TSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADS 6908

Query: 564  TTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAI 623
                 T PM +   +     +T    + +    K   T  L  G  +T          + 
Sbjct: 6909 EKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRET----SISQNASF 6964

Query: 624  LTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQ 683
             T T  +   + T     G+T    A++  T++     G+T +     P   Q+TV+ E 
Sbjct: 6965 STDTSIVLSEVPT-----GTT----AEVSRTEVT--SSGRTSI-----PGPSQSTVLPEI 7008

Query: 684  TRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASR 743
            + + +T  L  +  + E+   +I   +  P   T   + + ++S +   SQ   H   ++
Sbjct: 7009 STRTMTR-LFASPTMTESAEMTIPT-QTGPSGSTSQDTLTLDTSTTK--SQAKTHSTLTQ 7064

Query: 744  RQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLS 803
            R   SE    M   P  +    SS S    S++ +LL L  TT    + S     TI  S
Sbjct: 7065 RFPHSEMTTLMSRGPGDMSWQ-SSPSLENPSSLPSLLSLPATTSPPPISST-LPVTISSS 7122

Query: 804  QMAV-------PIQMTQEKRHSPESPSIAVVE-SELVAEYITTERTDEGTEVAFPLLVSH 855
             + V       P+  T     SPE  + +  + S    E +TT +    TE   P   + 
Sbjct: 7123 PLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTA 7182

Query: 856  RSQPQQPSQPQRTLLQHVAQSQTATQTS-VVVKSIPASSPGAIT--HIMQQALSSHTAFT 912
             S  + PS    +    +A S+T+  TS + + S    +  AI+  H ++ +     + +
Sbjct: 7183 ASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESIS 7242

Query: 913  KHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCF 972
              S +L      VE    ++    L   S    ++ ++ +  S      +     T+   
Sbjct: 7243 SLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPE 7302

Query: 973  QTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQL 1032
             +  ++ I      +   L +  +++I+ Q   P    ++    D   T   ++      
Sbjct: 7303 ISTTRKIIKFPTSPI---LAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHS--- 7356

Query: 1033 PTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPAS-SEKQTASQ 1091
             T+  + P + +  L  +    +P+    P +     +   P SQ+SL A  S    +S 
Sbjct: 7357 -TMTQRLPHSEITTLVSRGAGDVPRPSSLPVE-----ETSPPSSQLSLSAMISPSPVSST 7410

Query: 1092 VEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSP----VTSISPIQASEKTAVS 1147
            +     +  +SVT +   G+     T++   S+ P+ +SP     TS+  +  SE T  +
Sbjct: 7411 LPASSHSSSASVTSLLTPGQ--VKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDT 7468

Query: 1148 DILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPS-THMVVAGMANSTPQQQK 1206
            + +      A           + P   L  S  T    ++ + + M    ++  TP    
Sbjct: 7469 EKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSN 7528

Query: 1207 CRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIP 1266
             R+  S P+   SSLTTR             +R  +  ++ +  + A  ++  +      
Sbjct: 7529 TRKIQSEPA---SSLTTR-------------LRETSTSEETSLATEANTVLSKV------ 7566

Query: 1267 CHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSS 1318
               S+    E S    ++   +     E++ M QDI      GT P  S SS
Sbjct: 7567 ---STGATTEVSRTEAISFSRTSMSGPEQSTMSQDISI----GTIPRISASS 7611



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 223/1180 (18%), Positives = 438/1180 (37%), Gaps = 154/1180 (13%)

Query: 149  TTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK----- 203
            TT+T TS PV S        P  ++ AS+V+  PS     + +VS S   +         
Sbjct: 2212 TTNTETSIPVNSAG-----PPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHF 2266

Query: 204  -RRRTNSSSSSPVVLKEVPKAVVPV------SKTITVPVSGSPKMSNIMQSIANSLPPHM 256
              + T+S  +   +  E+   V P+      S   T P   SP ++   +    S  P  
Sbjct: 2267 PEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTT 2326

Query: 257  SPVKIT--FTKPSTQTT-NTTTQKVIIV------------TTSPSSTFVPNILSKSHNYA 301
            SP+ +T  FT+ ST +  N TT K   +            ++S S     +I S + +  
Sbjct: 2327 SPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVT 2386

Query: 302  AVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVT--AVVSST 359
                + PTS+   T    P + ++ +  + ++++  +++++PS   NT ++   + V  T
Sbjct: 2387 KTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGT 2446

Query: 360  PSVVMS-TVAQGVSTSAIKMASTR-LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQ 417
            PS +   T+   V TS+  +A +R + +  ++VS  T           ++P      V  
Sbjct: 2447 PSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDT--------ASGENPTSSNSVV-- 2496

Query: 418  QTQQQVAQPSPVSHQQQPQQSPLPP-GIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT 476
                  + P+P +       + LP  G   T    +     ++   ++P+      ++A 
Sbjct: 2497 -----TSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAH--SLLASTIEPATAFTPHLSAA 2549

Query: 477  LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536
            + T S++     +S  +++TT        +  T T PT S +    +ATP +   V  TS
Sbjct: 2550 VVTGSSA-----TSEASLLTTSESKAIHSSPQTPTTPT-SGANWETSATPESLLVVTETS 2603

Query: 537  GSII--------TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKG 588
             + +        T++  +++T   K  S+  +SG +   T +P T    +   + T+   
Sbjct: 2604 DTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFP-TLLPDTPAIPLTATEPTSSLA 2662

Query: 589  TTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAIL--TATRP------ITKMIVTQPKG 640
            T+    P   + +  L    E T+    T    A++  T + P      IT   VT+   
Sbjct: 2663 TSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPL 2722

Query: 641  IGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPV-TFQATVVSEQTRQLVTETLQQASRVA 699
              S+  P+  + P    Y  +G   V +   P  T  + V S+ +    T  L  +S   
Sbjct: 2723 HPSSTSPSKIVAPRNTTY--EGSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGL 2780

Query: 700  E--------------AGNSSIQEGKE---------------EPQNYTDSSSSSTESSQSS 730
            E              A +  I+ G                  P   T  S  +T    ++
Sbjct: 2781 ERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTAT 2840

Query: 731  QDSQPV-VHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS-----ATSTIK----ALL 780
            Q + P  + V  +  +      ++  +SP+  +  +++   +     +T T +      L
Sbjct: 2841 QSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSL 2900

Query: 781  ELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTER 840
            + +  ++    +S    P  D S  +  +  + EK  +P +  +   ++   + + +T  
Sbjct: 2901 DTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEK--NPRARMMTSTKAISASSFQSTGF 2958

Query: 841  TDEGTEVAFPLLVSHRSQ-PQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITH 899
            T+     A P +  H  + P   +   R   + ++    +  +S +  +  AS    +T 
Sbjct: 2959 TETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASK---LTT 3015

Query: 900  IMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPL 959
            +     ++ +  +     L TE    +E   L P      +++L    S  +Q      L
Sbjct: 3016 LFSTGQAARSGSSSSPISLSTE----KETSFLSPTASTSRKTSLFLGPSMARQPNILVHL 3071

Query: 960  EQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQ 1019
            + + L +         Q++   L + Q           +I  ++ T  + +     P   
Sbjct: 3072 QTSALTLSPTSTLNMSQEEPPELTSSQ-----------TIAEEEGTTAETQTLTFTPSET 3120

Query: 1020 HTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMS 1079
             T    V+   +        P+T    ++V     L +         I +  Q  Q   +
Sbjct: 3121 PTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNST 3180

Query: 1080 LPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQ 1139
             PA +E+  +S       +   S T      ++P    +I          +P T++ P++
Sbjct: 3181 WPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTV-PME 3239

Query: 1140 ASEKTAVSDILKMSLMEAQIDTNVEHMI--VDPPKKALATSMLTGEAGSL-PSTHMVVAG 1196
                T V  +   S       T++ H+      P K+   +ML  E  SL PS       
Sbjct: 3240 ----TTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTN 3295

Query: 1197 MANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQ 1236
            + + TP     R+S ++ S+V     T +    ++  TGQ
Sbjct: 3296 LYSGTP--GGTRQSLATMSSVSLESPTAR----SITGTGQ 3329



 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 265/1346 (19%), Positives = 471/1346 (34%), Gaps = 161/1346 (11%)

Query: 77   TTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAET 136
            TT   + +   SS   SI G    P    ++P+ +        A+  +  +A + +P +T
Sbjct: 6979 TTAEVSRTEVTSSGRTSIPG----PSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQT 7034

Query: 137  GSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSD 196
            G          +  ++ T +   + S  T + P   S  + ++    G   +  S S  +
Sbjct: 7035 GPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPH--SEMTTLMSRGPGDMSWQSSPSLEN 7092

Query: 197  EDEKPR--KRRRTNS----SSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
                P       T S    SS+ PV +   P   +PV+  +T     +  M +    +  
Sbjct: 7093 PSSLPSLLSLPATTSPPPISSTLPVTISSSP---LPVTSLLTSSPVTTTDMLHTSPELVT 7149

Query: 251  SLPP---HMSPVKITFTKPSTQT------TNTTTQKVIIVTT---SPSSTFVPNILSKSH 298
            S PP   H S  ++T  K +T T      TNT    V I ++   SPSS    +  SK+ 
Sbjct: 7150 SSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKAT 7209

Query: 299  NYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS----SSGSSSSTPSPIPNTVAVTA 354
            +   +T     + +A +T          + S+ S S     +GSS  T S I  +  ++ 
Sbjct: 7210 SPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSE 7269

Query: 355  V-VSSTPSVVMSTVAQGVSTSAIKMA-STRLP---SPKSLVSAPTQ-ILAQFPK---QHQ 405
            V + +T  +  + V     TS    A ST LP   + + ++  PT  ILA+  +   + Q
Sbjct: 7270 VSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQ 7329

Query: 406  QSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSP--------------LP-PGIKPTIQI 450
             SP     +              ++H    Q+ P              +P P   P  + 
Sbjct: 7330 TSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEET 7389

Query: 451  KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSS---NGAIMTTKLVTTPTGTQ 507
               S    ++  + PS     PV++TLP SS+S    V+S    G + TT+ V   +   
Sbjct: 7390 SPPSSQLSLSAMISPS-----PVSSTLPASSHSSSASVTSLLTPGQVKTTE-VLDASAEP 7443

Query: 508  ATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK-SLATLGGKIISSNIVSGTTTK 566
             T + P++S +   + AT    T  +       T V K   ++ G +  SS +    TTK
Sbjct: 7444 ETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTK 7503

Query: 567  IT----TIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT----------TLLNAGGEKTI 612
             T    TI +    +V  +         IQ  P  ++ T          T L       +
Sbjct: 7504 ATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVL 7563

Query: 613  QTVPTGAKPAI---------LTATRPITKMIVTQPKGIGSTVQPAAKIIPTK----IVYG 659
              V TGA   +          T+     +  ++Q   IG+  + +A  + T+     +  
Sbjct: 7564 SKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTESAKMTITT 7623

Query: 660  QQGKTQVLIKPKPVTFQATVVS-EQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTD 718
            Q G ++  ++       AT  S  +T  +V +           G          P    +
Sbjct: 7624 QTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKE 7683

Query: 719  SSSSSTESSQSSQDS-QPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSES----QSAT 773
            +S  S+  S  +  S  PV     +          ++ TS      D+   S     S++
Sbjct: 7684 TSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSS 7743

Query: 774  STIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRH-------SPESPSIAV 826
            S++      + TT K+   ++   P+ +     V    +  K         SP   +  +
Sbjct: 7744 SSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTM 7803

Query: 827  VESELVAE---YITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTS 883
             ++ ++     ++ T R    TE+A  L    R           T +  V        T+
Sbjct: 7804 GDTSVLTSTPAFLETRRIQ--TELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATT 7861

Query: 884  VVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSAL 943
             + K    S PG     +   +S+ T     +  + TE  E+       P       ++ 
Sbjct: 7862 EISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTST 7921

Query: 944  TQSQSAKQQKLSQPPLEQ--TQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRH 1001
              + S     ++   + Q  +  Q+ TL     +  + +   +  L  K    P  S+  
Sbjct: 7922 LDTSSTTSLTMTHSTISQGFSHSQMSTL---MRRGPEDVSWMSPPLLEK--TRPSFSLMS 7976

Query: 1002 QKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLA---VKTTQQLPKL 1058
               T        P P V  T          LP  ++  P  V  +L     KTT  L K 
Sbjct: 7977 SPAT------TSPSP-VSST----------LPESISSSPLPVTSLLTSGLAKTTDMLHK- 8018

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
                ++P          + + + A+SE  T ++   P  +   +VT +        + + 
Sbjct: 8019 ---SSEPVTNSPANLSSTSVEILATSEVTTDTEKTHP--SSNRTVTDVGTSSSGHESTSF 8073

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
            +   S   K+TSP+   S +   E T+VS         ++I T     +       L   
Sbjct: 8074 VLADSQTSKVTSPMVITSTM---EDTSVSTSTPGFFETSRIQTEPTSSL------TLGLR 8124

Query: 1179 MLTGEAGSLPSTHM--VVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQ 1236
              +   G+  +T M  V++G+      +    E  SS  T  S      + P     T  
Sbjct: 8125 KTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTETIT 8184

Query: 1237 FMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEET 1296
             +   ++  + AE     I  Q  P  + P  + +  +      +E ++  +Q+    E 
Sbjct: 8185 RLPTSSIMTESAE---MMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEM 8241

Query: 1297 AMEQDIDSSTEDGTEPSPSQSSAERS 1322
                    S   G    PSQSS E +
Sbjct: 8242 TTL----VSRSPGDMLWPSQSSVEET 8263



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 266/1326 (20%), Positives = 472/1326 (35%), Gaps = 189/1326 (14%)

Query: 21   RKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIA 80
            RK++ E  + + + LR     T E+  L  E + VLS  +     EV R    E ++   
Sbjct: 7530 RKIQSEPASSLTTRLRETS--TSEETSLATEANTVLSKVSTGATTEVSRT---EAISFSR 7584

Query: 81   HNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKE 140
             +MSGP  S+   +     +  +PR+             A++ +  +A + +  +TG  E
Sbjct: 7585 TSMSGPEQST---MSQDISIGTIPRIS------------ASSVLTESAKMTITTQTGPSE 7629

Query: 141  VVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSG----STVYVKSVSCSD 196
                S  +  +  T + V + SI     P P    S +   P G    S  +VK    S 
Sbjct: 7630 STLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTS-MGRGPGGVSWPSPPFVKET--SP 7686

Query: 197  EDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVS------------GSPKMSNI 244
                      T+    S   L  +P + +PV+  +T   +            G+   S++
Sbjct: 7687 PSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSL 7746

Query: 245  MQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVT 304
              +    L  +          PST T  T      + TTS       ++L+ S      +
Sbjct: 7747 STTSHERLTTYKDTAHTEAVHPSTNTGGTN-----VATTSSGYKSQSSVLADSSPMCTTS 7801

Query: 305  KLVPTSVIAST-----TQKPPVVITAS------QSSLVSNSSSGSSSSTPSPIPNTVAVT 353
             +  TSV+ ST     T++    + +S      +SS    +SSG+  ST      T A T
Sbjct: 7802 TMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATT 7861

Query: 354  AV----VSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPK 409
             +    V+S P    ST++  +ST  +   ST     +S         +      Q +  
Sbjct: 7862 EISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTST 7921

Query: 410  QQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP----GIKPTIQIKQESGVKIITQQVQP 465
                     T          SH Q        P     + P +  K      +++    P
Sbjct: 7922 LDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMS---SP 7978

Query: 466  SKILPKPVTATLPTS-SNSPIMVVS--SNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRM 522
            +   P PV++TLP S S+SP+ V S  ++G   TT ++   +           S S+  +
Sbjct: 7979 ATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEIL 8038

Query: 523  AATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITT--IPMTSKPNVIV 580
            A +       KT   S  TV     ++ G +  S  +    T+K+T+  +  ++  +  V
Sbjct: 8039 ATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSV 8098

Query: 581  VQKTTG--KGTTIQGLPGKNVVTTLLNAGGEK----------TIQTVPTGAKPAILTATR 628
               T G  + + IQ  P  ++   L      +           +  VPTGA   +  +  
Sbjct: 8099 STSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEV--SRT 8156

Query: 629  PITKMIVTQPKGIGS-TVQPAAKI-----IPTKIVYGQQGKTQVLIKPKP---------- 672
             +T    T   G    TV P         +PT  +  +  +  +  +  P          
Sbjct: 8157 EVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHT 8216

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNS------SIQEGKEEPQNYTDSSSSSTES 726
            V    T    +T   VT+    +        S        Q   EE      SS+SS  S
Sbjct: 8217 VDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEE-----TSSASSLLS 8271

Query: 727  SQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQD---VSSE-SQSATSTIKALLEL 782
              ++    PV   +       S    ++     +I  D   +S E   S+TS + +    
Sbjct: 8272 LPATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHE 8331

Query: 783  QQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTD 842
            + TT+++ ++++  QP+   +  AV    T    H  +S  ++  E+      + T  T 
Sbjct: 8332 RLTTLEDTVDTEDMQPS---THTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTM 8388

Query: 843  EGTEVAF---PLLVSHRSQPQQPSQPQRTLLQHVAQSQ---TATQTSVVVKSIPASSPGA 896
              T V+        + R Q  +P+    + L+  + S+   +AT+ S V+  +P+   GA
Sbjct: 8389 GETSVSISTSDFFETSRIQ-IEPTSSLTSGLRETSSSERISSATEGSTVLSEVPS---GA 8444

Query: 897  ITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQS-QSAKQQKLS 955
             T + +  + S    ++ +   G ++  +    + +  T L     +T+S +SA   +  
Sbjct: 8445 TTEVSRTEVIS----SRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETG 8500

Query: 956  QP--PLEQTQLQVKTLQCFQTKQKQTI-----HLQADQLQHKLP-QMPQLSIRHQKLTPL 1007
             P    E T     +   F +    T      H +   L  + P  +P  S+      P 
Sbjct: 8501 SPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSL------PS 8554

Query: 1008 QQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLA---VKTTQQLPKLQQAPNQ 1064
             +E +     +        +    LP  ++  P  V  +L    VKTT  L    +  ++
Sbjct: 8555 VEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDML----RTSSE 8610

Query: 1065 PKIYVQPQTPQSQMSLPASSE-----KQTASQVEQPIITQGSSVTK-----------ITF 1108
            P+    P    +   + A+SE     ++       P++  G+ + K           +T 
Sbjct: 8611 PETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTT 8670

Query: 1109 EGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIV 1168
            +   P   T   G +SV       TS      +  T  +  L   L E  I T+ E    
Sbjct: 8671 KPTSPMATTSTLGNTSVS------TSTPAFPETMMTQPTSSLTSGLRE--ISTSQETSSA 8722

Query: 1169 DPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDP 1228
               + A  + M TG    +  T  +  G   STP          + ST+   ++T  I  
Sbjct: 8723 -TERSASLSGMPTGATTKVSRTEALSLG-RTSTPG--------PAQSTISPEISTETITR 8772

Query: 1229 PAVPAT 1234
             + P T
Sbjct: 8773 ISTPLT 8778



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 195/968 (20%), Positives = 344/968 (35%), Gaps = 209/968 (21%)

Query: 76    LTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNA--SLPVP 133
             + T+  + S P++++ W I     +P + +  P   F    + V++ A  H A  S  +P
Sbjct: 10583 IQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNF-FHSELDTVSSTATSHGADVSSAIP 10641

Query: 134   AETGSKEVVCYSYTSTTS-TPTSTPVPSGSIATVKSPRPASPASNVVVLPS--GSTV--Y 188
                   E+   +   T S T TST  P+      KSP      +  +  P+   ST+   
Sbjct: 10642 TNISPSELDALTPLVTISGTDTSTTFPT----LTKSPHETETRTTWLTHPAETSSTIPRT 10697

Query: 189   VKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSI 248
             + + S  + D  P       + +SS + +  V                 SP   +++ S 
Sbjct: 10698 IPNFSHHESDATPSIATSPGAETSSAIPIMTV-----------------SPGAEDLVTS- 10739

Query: 249   ANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSK--SHNYAAVTKL 306
                                 Q T++ T + + + T   S   P  ++   +H  A  +  
Sbjct: 10740 --------------------QVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSA 10779

Query: 307   VPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV---------- 356
             +PTS I+    +   ++T+  +SL + +S+ + + T SP      V+ V           
Sbjct: 10780 IPTSTISPAVSR---LVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVP 10836

Query: 357   -----------SSTPSVVMSTVAQGVSTSAIKMASTRLP--------SPKSLVSAPTQIL 397
                         +TPS+  S  A+  S       ST +P        S ++++S    IL
Sbjct: 10837 WTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPIL 10896

Query: 398   AQFPKQHQQSPKQQLYQVQQQTQQQVAQPSP-------------VSHQQQPQQSPLP--- 441
                P + + +P       ++ +    A P+P             V+  +    + +P   
Sbjct: 10897 TLSPGEPETTPSMATSHGEEASS---AIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILT 10953

Query: 442   ---------PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                      P +  +   +  S V  +  +V P  +     ++   TS+  P + +S  G
Sbjct: 10954 FSLGEPETTPSMATSHGTEAGSAVPTVLPEV-PGMVTSLVASSRAVTSTTLPTLTLSP-G 11011

Query: 493   AIMTTKLVTTPTGTQATYTRPTVSPSI--------------------------GRMAATP 526
                TT  + T  G +A+ T PTVSP +                          G +  TP
Sbjct: 11012 EPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTP 11071

Query: 527   GAATYVKTTSGSII---TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIV--- 580
               AT     + S +   TV P     +   + SS  V+ TT  I T+  +S+P       
Sbjct: 11072 SMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTL-SSSEPETTPSMA 11130

Query: 581   ----VQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPT----GAKPAILTA--TRPI 630
                 V+ ++   T    +PG  +VT+L+ +    T  T+PT      +P   T+  T   
Sbjct: 11131 TSHGVEASSAVLTVSPEVPG--MVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSE 11188

Query: 631   TKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQ-----VLIKPKPVTFQATVVSEQTR 685
              KMI   P      V P  + + T +V     +T       +   +P T  + V    T 
Sbjct: 11189 AKMISAIPT---LAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTE 11245

Query: 686   -------------------QLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTES 726
                                 LVT   + +S +     S     + +    T +S  +  S
Sbjct: 11246 ASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRT-TSRFSHSELDTMPSTVTSPEAESS 11304

Query: 727   SQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLE--LQQ 784
             S  S    P +  + +     S  +I+  T PT+      SE+ ++  T  A+    + +
Sbjct: 11305 SAISTTISPGIPGVLTSLVTSSGRDIS-ATFPTVPESPHESEATASWVTHPAVTSTTVPR 11363

Query: 785   TTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEG 844
             TT           P+I  S  A           SP+ P       ++V   +T+  TD  
Sbjct: 11364 TTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVP-------DMVTSQVTSSGTD-- 11414

Query: 845   TEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQA 904
             T +  P L     +P+       T    +  S+  T TS  + ++P  SPGA   +    
Sbjct: 11415 TSITIPTLTLSSGEPE-------TTTSFITYSE--THTSSAIPTLPV-SPGASKMLTSLV 11464

Query: 905   LSSHTAFT 912
             +SS T  T
Sbjct: 11465 ISSGTDST 11472



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 190/841 (22%), Positives = 331/841 (39%), Gaps = 156/841 (18%)

Query: 54   KVLSISTE-RHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAF 112
            K+L+ S + +   E+  ++N E  T +  N SG  S S    +        P+   Q   
Sbjct: 5103 KILATSKDSKDTKEIFPSINTEE-TNVKANNSGHESHSPALADSET-----PKATTQMVI 5156

Query: 113  TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTS--TPVPSGSIATVKSPR 170
            T T    A +      S+PV    GS E      T+    PT   TP    +  + +S  
Sbjct: 5157 TTTVGDPAPST-----SMPVH---GSSET-----TNIKREPTYFLTPRLRETSTSQESSF 5203

Query: 171  PASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKT 230
            P   +  +  +P+G+   V S               T  +SSS +   +  K+ VP   T
Sbjct: 5204 PTDTSFLLSKVPTGTITEVSS---------------TGVNSSSKISTPDHDKSTVPPD-T 5247

Query: 231  ITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFV 290
             T           I +   +S+    + + IT T+ S   + + +   +  +T+ S    
Sbjct: 5248 FT---------GEIPRVFTSSIKTKSAEMTIT-TQASPPESASHSTLPLDTSTTLSQGGT 5297

Query: 291  PNILSKSHNYAAVTKLV---PTSVIASTTQKPPVVITASQSSLVSN----SSSGSSSSTP 343
             + +++   Y+ VT L+   P +V   TT  PPV  T+S SSL+S+    S S  SS++P
Sbjct: 5298 HSTVTQGFPYSEVTTLMGMGPGNVSWMTT--PPVEETSSVSSLMSSPAMTSPSPVSSTSP 5355

Query: 344  -----SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILA 398
                 SP+P T   T+V+ +T  V+ +T  + V++S   ++S     P     A  +  A
Sbjct: 5356 QSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERP-----ATYKDTA 5410

Query: 399  QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKI 458
                    S    +  V        +Q S ++  +  + +PL      T     ++ V  
Sbjct: 5411 HTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPL----MSTTSTLGDTSVST 5466

Query: 459  ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPS 518
             T  +  +  +      T PT+S SP +  SS     ++   TT T T  +Y  PT    
Sbjct: 5467 STPNISQTNQIQ-----TEPTASLSPRLRESSTSEKTSS---TTETNTAFSYV-PT---- 5513

Query: 519  IGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIP-MTSKPN 577
                    GA T    T    I+    S++ L    I+ +I +G  T++ T P MT    
Sbjct: 5514 --------GAITQASRTE---ISSSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAE 5562

Query: 578  VIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI----------------------QTV 615
            + V  +TT  G T QG+   +  TTL   G   T+                       T 
Sbjct: 5563 MTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTT 5622

Query: 616  PTGAKPA--------ILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVL 667
            P   + +         +T+  P++    T P+ I S+  P   ++ + +V      T VL
Sbjct: 5623 PPVEETSSGFSLMSPSMTSPSPVSS---TSPESIPSSPLPVTALLTSVLV----TTTNVL 5675

Query: 668  --IKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
                P+PVT     +S  T++ +T     A    EA ++S+         +T+++ ++  
Sbjct: 5676 GTTSPEPVTSSPPNLSSPTQERLTTYKDTAH--TEAMHASM---------HTNTAVANVG 5724

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSS--ESQSATSTIKALLE-L 782
            +S S  +SQ  V   +   +  S   I      T +     +  E++  T +  +L+  L
Sbjct: 5725 TSISGHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGL 5784

Query: 783  QQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRH----SPESPSIAVVESELVAEYITT 838
            + T   E++ +     T+ LS+  VP   T E       +    +I+  +   ++ YI+T
Sbjct: 5785 RDTRTSEEINTVTETSTV-LSE--VPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYIST 5841

Query: 839  E 839
            E
Sbjct: 5842 E 5842



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 274/1358 (20%), Positives = 489/1358 (36%), Gaps = 228/1358 (16%)

Query: 109   QTAFTVTANAVANAAIQHNAS--------LPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
             Q  FT+  ++ A+    H+A+        +  P   G ++V   S  S   T   + + S
Sbjct: 8799  QGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVS 8858

Query: 161   GSIATVKSPRPASPASNVVVLPSGST-----VYVKSVSCSDEDEKPRKRRRTNSSSSSPV 215
              S  T  SP  ++P+ +    P   T     V +K+    D   +P     T S  S  +
Sbjct: 8859  LSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPV----TTSPPSMNI 8914

Query: 216   VLKEVPKAVVPVSKTITVPVSGSPKMSNI-----MQSIANSLPPHMSPVKITFTKPSTQT 270
                E         +T  + +S +  ++ +      Q   +S P    P K+T     +  
Sbjct: 8915  TSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVT-----SPV 8969

Query: 271   TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL 330
               ++T K I+ TT P+S+ +  I  +S      + L PT    ST+Q+   + +A++ S 
Sbjct: 8970  VTSSTIKDIVSTTIPASSEITRIEMES-----TSTLTPTPRETSTSQE---IHSATKPST 9021

Query: 331   VSNSSSGSSSSTPSPIPNTVAVTAVVSST--PSVVMSTVAQGVSTSAIKMASTR-LPSPK 387
             V   +  S++   S       +T V+SS+  PS   ST++Q +ST  I   ST  + +  
Sbjct: 9022  VPYKALTSATIEDS-------MTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTES 9074

Query: 388   SLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPT 447
             + ++  TQ  +                    T    +Q    SH Q        PG  P 
Sbjct: 9075  TEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQG--FSHSQMTALMSRTPGDVPW 9132

Query: 448   IQ---IKQESGVKIITQQVQPSKILPKPVTATLPTSSNS---PIMVVSSNGAIMTTKLVT 501
             +    +++ S          P      PV++TLP S +S   P+  + ++G + TT+L+ 
Sbjct: 9133  LSHPSVEEASSASFSLSS--PVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLG 9190

Query: 502   TPTGTQATYTRPTVSPSIGRMAATPGAATYVK-------TTSG----SIITVVPKSLATL 550
             T +  + T + P +S +   + A     T  +        TSG    S  +V+  S+ T 
Sbjct: 9191  TSSEPE-TSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTK 9249

Query: 551   GGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEK 610
                 +     +G T  +T+ P  S  + I   +T  K +   GL   ++     +A  + 
Sbjct: 9250  ATSSMGITYPTGDTNVLTSTPAFSDTSRI---QTKSKLSLTPGLMETSISEETSSATEKS 9306

Query: 611   TI-QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI-----IPTKIVYGQQGKT 664
             T+  +VPTGA   + + T  I+    + P    ST+     +     I T +   ++  T
Sbjct: 9307  TVLSSVPTGATTEV-SRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLT--RKEST 9363

Query: 665   QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724
              + I PK     AT          T TL  +S  +  G  S    +      T   S   
Sbjct: 9364  DMAITPKTGPSGATSQG-------TFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGP 9416

Query: 725   E-----SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKAL 779
             E     S  S + + P   +++S          +  TSP+ +Y   S  S S+   + +L
Sbjct: 9417  EDVSWPSPLSVEKNSPPSSLVSS----------SSVTSPSPLYSTPSGSSHSSPVPVTSL 9466

Query: 780   LELQQTTVKEKLESKPRQPTIDLSQMAVPI-QMTQEKRHSPESPSIAVVESELVAEYITT 838
                      + L++     T     M +   +     + + E+ +I V E+   +   TT
Sbjct: 9467  FTSIMMKATDMLDASLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETT 9526

Query: 839   ERTDE----------GTEVAFPLLVSHRSQPQQPS--------------QPQRTLLQHVA 874
               T+E           T+V  P++ S   +    S              +   +L   + 
Sbjct: 9527  SATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLR 9586

Query: 875   QSQTA------TQTSVVVKSIPA-----------------SSPGAITHIMQQALSSHTAF 911
             +++T+      T+TS V+  +P+                 S PG     M   +S     
Sbjct: 9587  ETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVT 9646

Query: 912   TKHSEELGTEEGEVEEMDTLDPQTGLFYRSA------------LTQSQSAKQQKLSQPPL 959
                +  + TE  E+    T+  QTG    ++            L+ + S   Q LS    
Sbjct: 9647  RLSTSPIMTESAEI----TITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHS-- 9700

Query: 960   EQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMP-QLSIRHQKLTPLQQEQAQPKPDV 1018
             E T L  +  +       + +  +  +    L  +P   S+     T L    + P P  
Sbjct: 9701  EMTNLMSRGPESLSWTSPRFV--ETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVT 9758

Query: 1019  QHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLP----------KLQQAPNQP--K 1066
                   +V     L T  +  P+T        T+ ++P          K+  + N    K
Sbjct: 9759  SLILPGLVKTTEVLDT--SSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAK 9816

Query: 1067  IYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITF-----EGRQPPT--VTKI 1119
             +       +S  S+ A SE  T +     I +     T  T      E R+ PT     +
Sbjct: 9817  VRTSSSVHESHSSVLADSET-TITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSL 9875

Query: 1120  TGGSSVPKLTSPVTSIS---------PIQASEKTAVSDILK----------MSLMEAQID 1160
             T G      +   TSI+         P  A+ + ++++I+            S M   I 
Sbjct: 9876  TPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDII 9935

Query: 1161  TNVEHMIVDPPKKALATSM-LTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGS 1219
             T V   +      + +T M +T +  S  +T      +A +T    +   S   P  + S
Sbjct: 9936  TEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTH-STVPPRFLHS 9994

Query: 1220  SLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSG 1279
              +TT     P  P+    + ++      +        + ++P    P  SS+     PS 
Sbjct: 9995  EMTTLMSRSPENPSWKSSLFVEKTSSSSS--------LLSLPVTTSPSVSSTLPQSIPSS 10046

Query: 1280  LLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQS 1317
                + +  +         M +  D+STE GT  SP+ S
Sbjct: 10047 SFSVTSLLTP-------GMVKTTDTSTEPGTSLSPNLS 10077



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 185/928 (19%), Positives = 327/928 (35%), Gaps = 116/928 (12%)

Query: 22   KLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAH 81
            ++++E  + + S LR     + E+     E S VLS        EV R    E +++   
Sbjct: 8405 RIQIEPTSSLTSGLRETS--SSERISSATEGSTVLSEVPSGATTEVSRT---EVISSRGT 8459

Query: 82   NMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEV 141
            +MSGP+   +++I        + RL   T+  +T +A +   I+  +       T + + 
Sbjct: 8460 SMSGPD---QFTISPDISTEAITRL--STSPIMTESAESAITIETGSPGATSEGTLTLDT 8514

Query: 142  VCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKP 201
               ++ S T +  S       + T+ S  P         +P  S   V+  S        
Sbjct: 8515 STTTFWSGTHSTASPGFSHSEMTTLMSRTPGD-------VPWPSLPSVEEASSVSSSLSS 8567

Query: 202  RKRRRTNSSSSSPVVLKEVPKAVV------PVSKTITVPVSGSPKMS---NIMQSIANSL 252
                 T+  S+ P  +   P  V       PV  T  +  S  P+ S   N+  + A  L
Sbjct: 8568 PAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEIL 8627

Query: 253  PPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK-LVPTSV 311
                         PS+ T       VI    SPSS     + +K  +  A T  L  TSV
Sbjct: 8628 ATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSV 8687

Query: 312  IASTTQKPPVVITASQSSLVSN------------------SSSGSSSSTPSPIPNTVAVT 353
              ST   P  ++T   SSL S                   S SG  +   + +  T A++
Sbjct: 8688 STSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALS 8747

Query: 354  AVVSSTPSVVMSTVAQGVSTSAIKMASTRL------------------PSPKSLVSAPTQ 395
               +STP    ST++  +ST  I   ST L                   S +   +  T 
Sbjct: 8748 LGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTS 8807

Query: 396  ILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESG 455
              A +P  H  +  +  +             +P+S   +    P  P ++ T        
Sbjct: 8808 SRASWPGTHSAATHRSPHS---------GMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVS 8858

Query: 456  VKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTV 515
            +  +T         P P+ +T   SS+S  + V+S   + T  ++ T      +    T 
Sbjct: 8859 LSAVTS--------PSPLYSTPSESSHSSPLRVTS---LFTPVMMKTTDMLDTSLEPVTT 8907

Query: 516  SPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSK 575
            SP    + +    AT   T     I +   +  T  G I +        +    +P  SK
Sbjct: 8908 SPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISAR---QEFYSSYPGLPEPSK 8964

Query: 576  PNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP--TGAKPAILTATRPITKM 633
                VV  +T K      +P  + +T  +      T+   P  T     I +AT+P T  
Sbjct: 8965 VTSPVVTSSTIKDIVSTTIPASSEITR-IEMESTSTLTPTPRETSTSQEIHSATKPST-- 9021

Query: 634  IVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQ 693
             V       +T++ +     T+++   +G +     P   T    + +E   +L T  ++
Sbjct: 9022 -VPYKALTSATIEDSM----TQVMSSSRGPS-----PDQSTMSQDISTEVITRLSTSPIK 9071

Query: 694  QASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIA 753
              S        +   G       T  +S++  S   S  SQ   H   +     +  ++ 
Sbjct: 9072 TESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVP 9131

Query: 754  METSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQ 813
              + P++  ++ SS S S +S +        +T+ + + S     T  L+   V      
Sbjct: 9132 WLSHPSV--EEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELL 9189

Query: 814  EKRHSPES---PSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLL 870
                 PE+   P+++   +E++A    TE T +  ++    +V+     + PS       
Sbjct: 9190 GTSSEPETSSPPNLSSTSAEILA---ITEVTTDTEKLEMTNVVTSGYTHESPSSV----- 9241

Query: 871  QHVAQSQTATQTSVVVKSIPASSPGAIT 898
              +A S T   TS +  + P      +T
Sbjct: 9242 --LADSVTTKATSSMGITYPTGDTNVLT 9267



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 237/1248 (18%), Positives = 455/1248 (36%), Gaps = 234/1248 (18%)

Query: 31    VISALRAQGDLTK---EKKDLLGELSKVLSISTERHRAEVRRAVNDERLT--TIAHNMSG 85
             V + + A  ++T+   E    L    +  S S E H A     V  + LT  TI  +M+ 
Sbjct: 8979  VSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQ 9038

Query: 86    PNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYS 145
               SSS      R   P    +    +  V      +     +  + +  +TGS       
Sbjct: 9039  VMSSS------RGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATS-- 9090

Query: 146   YTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRR 205
                T +  TST   SG+ +T       S  + ++    G   ++   S  +         
Sbjct: 9091  -RGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLS 9149

Query: 206   RTNSSSSSPV---VLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262
                 +SSSPV   +   +  + +PV+  +T  +  + ++         S PP++S     
Sbjct: 9150  SPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAE 9209

Query: 263   FTKPSTQTTNTTTQKVIIVTTS------PSSTFVPNILSKSHNYAAVTKLV-PTSVIAST 315
                 +  TT+T   ++  V TS      PSS    ++ +K+ +   +T     T+V+ ST
Sbjct: 9210  ILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLTST 9269

Query: 316   TQ---------KPPVVITAS--QSSLVSNSSSGSSSST---------PSPIPNTVAVTAV 355
                        K  + +T    ++S+   +SS +  ST          + +  T A+++ 
Sbjct: 9270  PAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSS 9329

Query: 356   VSSTPSVVMSTVAQGVSTSAIKMASTRLP---------SPKSLVSAPTQ---------IL 397
              +S P    ST++   S   I   ST L          +PK+  S  T            
Sbjct: 9330  RTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSST 9389

Query: 398   AQFPKQH----QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQE 453
             A +P  H    Q+ P+  +     +  + V+ PSP+S ++    S L      T      
Sbjct: 9390  ASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVT------ 9443

Query: 454   SGVKIITQQVQPSKILPKPVTATL----------------PTSSNSPIMVVSSNGAIMTT 497
             S   + +     S   P PVT+                  P ++++P M ++S+ ++  +
Sbjct: 9444  SPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPNMNITSDESLAAS 9503

Query: 498   KLVTTPTG------TQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLG 551
             K  T          T A++   T S +    +++PG +   K  S  + +          
Sbjct: 9504  KATTETEAIHVFENTAASHVE-TTSATEELYSSSPGFSEPTKVISPVVTS---------- 9552

Query: 552   GKIISSNIVSGT---TTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGG 608
                I  N+VS T   ++ IT I + S  ++    + T    T Q +      +T+L    
Sbjct: 9553  -SSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRET---RTSQDITSSTETSTVL---- 9604

Query: 609   EKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLI 668
                   +P+GA P +       T+++ +    I    Q    +  +  V  +   + ++ 
Sbjct: 9605  ----YKMPSGATPEVSR-----TEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMT 9655

Query: 669   KPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQ 728
             +   +T             VT  L  +       +S++ +G     ++++ ++  +   +
Sbjct: 9656  ESAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGL----SHSEMTNLMSRGPE 9711

Query: 729   SSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL--ELQQTT 786
             S   + P    + + R   S   + + TS + +   +   S S+   + +L+   L +TT
Sbjct: 9712  SLSWTSP--RFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTT 9769

Query: 787   VKEKLESKPR---QPTIDLSQMAVP----IQMTQEKRHSPESPSIAVVE-SELVAEYITT 838
                   S+P+    P +  + + +P    I    EK H   + ++A V  S  V E  ++
Sbjct: 9770  EVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSS 9829

Query: 839   ERTDEGTEVAFPLL---------VSHRSQP------QQPSQPQRTLLQHVAQSQTA---- 879
                D  T +  P +             S P      + P++P  +L     ++ T+    
Sbjct: 9830  VLADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETT 9889

Query: 880   --TQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGL 937
               T+TS V+  +P S+   ++  M + +SS+      S++            T+ P    
Sbjct: 9890  SITETSAVLYGVPTSATTEVS--MTEIMSSNRIHIPDSDQ-----------STMSPD--- 9933

Query: 938   FYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQL 997
                  +T+  S+          E TQ+ + T +       Q+    A             
Sbjct: 9934  IITEVITRLSSSSMMS------ESTQMTITTQKSSPGATAQSTLTLATTT---------- 9977

Query: 998   SIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPK 1057
                     PL +  +   P   H++         + TLM++ P+              P 
Sbjct: 9978  -------APLARTHSTVPPRFLHSE---------MTTLMSRSPEN-------------PS 10008

Query: 1058  LQQAPNQPKIYVQPQTPQSQM-SLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTV 1116
              + +     ++V+  +  S + SLP ++    +S + Q I +   SVT +   G    T 
Sbjct: 10009 WKSS-----LFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTD 10063

Query: 1117  TKITGGSSV-PKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNV 1163
             T    G+S+ P L+   TS+  + ASE T  +D  K+    +   TNV
Sbjct: 10064 TSTEPGTSLSPNLSG--TSVEILAASEVT--TDTEKIHPSSSMAVTNV 10107



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 251/1287 (19%), Positives = 433/1287 (33%), Gaps = 224/1287 (17%)

Query: 154  TSTPVPSGSIATVK-----SPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTN 208
            TS   PS   + VK     S R  SP+      P  +   V+ +S S  D        + 
Sbjct: 3640 TSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDIL------ST 3693

Query: 209  SSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN-SLPPHMSPVKITFTKPS 267
            S + S    ++VP ++V      T     +P  + +  S++        S    T T  +
Sbjct: 3694 SWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSA 3753

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
             Q   T  +  +    SP+++ +P   S  H  +AVT          T  +P    T+ +
Sbjct: 3754 PQGATTPQELTLETMISPATSQLP--FSIGHITSAVTPAAMARSSGVTFSRPDP--TSKK 3809

Query: 328  SSLVSNSSSGSSSSTPSPIPNTVAVTAVV----SSTPSVVMSTVAQ-GVSTSAIKMASTR 382
            +   S     ++S+ P  +P + A T  V    + TP        Q  ++T A   + + 
Sbjct: 3810 AEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSW 3869

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
                KS  SAP                + +  V + T ++V   S V          L  
Sbjct: 3870 NEKEKSTPSAPWIT-------------EMMNSVSEDTIKEVTSSSSVLRTLNTLDINLES 3916

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS---------SNSPIMVVSSNGA 493
            G   +   K     +I   +    K    P T T+ T+         S+S I   S++  
Sbjct: 3917 GTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSK 3976

Query: 494  IMTTKLVTTPTGTQATYTRPTVS-PSIGRMAATPGA---------ATYVKTTS------- 536
            + T+ +VTT T  QA  +  T + P   R    P +         + Y+ T+S       
Sbjct: 3977 L-TSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSII 4035

Query: 537  ----GSIITVVPKSLATLGGKIISSNIV---------SGTTTKITTIP-MTSKPNVIVVQ 582
                 + IT  P++  T   +I SS +          S   T+++  P MT    +I+  
Sbjct: 4036 SSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAM 4095

Query: 583  KTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTVPTGAKPAILTA----TRPITKMIVTQ 637
            +T+  G T    P  +   T    G    T Q      K  + +     T   +   V +
Sbjct: 4096 QTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEE 4155

Query: 638  PKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASR 697
                 S V   A   P+ I+   QG +     P    F            ++ET     +
Sbjct: 4156 TSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVF------------LSET-SGLGK 4202

Query: 698  VAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETS 757
              +    S++ G   P N + ++  +  + ++S+D++ + H                   
Sbjct: 4203 TTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSA----------------- 4245

Query: 758  PTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRH 817
                  D +  +  ATS+  + +            +KP + T  L    +   +T     
Sbjct: 4246 ------DTAVTNMEATSSEYSPIPGH---------TKPSKATSPLVTSHIMGDITS---- 4286

Query: 818  SPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQ 877
                 S +V  S    E  T    ++G      L     SQ    +    T++ HV+   
Sbjct: 4287 -----STSVFGSSETTEIETVSSVNQG------LQERSTSQVASSATETSTVITHVSSGD 4335

Query: 878  TATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMD-TLDPQTG 936
              T    V K+    S G       Q ++S   FT  S    T     E    T+  QTG
Sbjct: 4336 ATTH---VTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTITTQTG 4392

Query: 937  LFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQ 996
                 A TQ         + P L +T L V T    Q+++   I      +    P    
Sbjct: 4393 P--TGAATQGPYLLDTS-TMPYLTETPLAV-TPDFMQSEKTTLISKGPKDVSWTSPPSVA 4448

Query: 997  LSIRHQKLTPLQQEQAQPKPDV---QHTQHPMVAKD--------------------RQLP 1033
             +     LTP       P       QHT  P+ A                         P
Sbjct: 4449 ETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSP 4508

Query: 1034 TLMAQPPQTVVQVLAVKTTQQL--PKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQ 1091
              +  P   ++  LA  T  +   P + +A              S  +LP SSE  TA+ 
Sbjct: 4509 QNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHS--TLPVSSEPSTATS 4566

Query: 1092 VEQPIITQGSSVTKITFEGRQPPTV-----TKITGG----SSVPKLTSPVTSISPIQASE 1142
               P  + G ++  I+  G +   +     + +T G    S++ ++ S   S   +    
Sbjct: 4567 PMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVS 4626

Query: 1143 KTAVSDILKM---------------SLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSL 1187
              A+++  KM               S     I +     + + P   ++T M T + GS 
Sbjct: 4627 VGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSS 4686

Query: 1188 PSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQ-- 1245
             +T  +   +  ST        S  +PS V       KI       T     +++V Q  
Sbjct: 4687 GATSKIPLALDTST-----LETSAGTPSVVTEGFAHSKI------TTAMNNDVKDVSQTN 4735

Query: 1246 ------KKAEESPAEIIIQAIPQ---YAIPCHSSSNVVVEPSGLLELNNFTSQQLD---D 1293
                    +  S A +++  +P    +    HS+S+ V   S L      T+ ++D   +
Sbjct: 4736 PPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLE 4795

Query: 1294 EETAMEQDIDSSTEDGTEPSPSQSSAE 1320
              T+  Q + ++ +D +  S + +  E
Sbjct: 4796 TVTSSPQSMSNTLDDISVTSAATTDIE 4822



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 215/1096 (19%), Positives = 385/1096 (35%), Gaps = 155/1096 (14%)

Query: 207  TNSSSSSPVVLKEVPK-AVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265
            T+S +    VL +VP  A   +SK     + G P  S I   I+       S   +  T+
Sbjct: 7842 TSSGTKMSTVLSKVPTGATTEISKEDVTSIPG-PAQSTISPDISTRTVSWFSTSPV-MTE 7899

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325
             +  T NT T  +   T   S+    +  S +  ++ +++    S +++  ++ P  ++ 
Sbjct: 7900 SAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSW 7959

Query: 326  SQSSLVSNS----SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381
                L+  +    S  SS +T SP P +  +   +SS+P  V S +  G++ +   +  +
Sbjct: 7960 MSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKS 8019

Query: 382  RLP---SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQS 438
              P   SP +L S   +ILA                   +      +  P S++      
Sbjct: 8020 SEPVTNSPANLSSTSVEILA-----------------TSEVTTDTEKTHPSSNRTVTDVG 8062

Query: 439  PLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTK 498
                G + T  +  +S    +T         P  +T+T+  +S S     S+ G   T++
Sbjct: 8063 TSSSGHESTSFVLADSQTSKVTS--------PMVITSTMEDTSVS----TSTPGFFETSR 8110

Query: 499  LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG-----SIITVVPKSLATLGGK 553
            + T PT +     R T S S G   AT  +       +G     S   V   S  ++ G 
Sbjct: 8111 IQTEPTSSLTLGLRKT-SSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGF 8169

Query: 554  IISSNIVSGTTTKITTIP----MTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
               +     +T  IT +P    MT    +++  +T   G+T +     ++ TT       
Sbjct: 8170 AQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTT------P 8223

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIK 669
              ++T  T      +T     ++M     +  G  + P+   +                 
Sbjct: 8224 NWVETHST------VTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTS 8277

Query: 670  PKPVTFQATVVSE-QTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST---- 724
            P PV+  +T+V +  +  L   +L     V       I     EP   + S+ SST    
Sbjct: 8278 PSPVS--STLVEDFPSASLPVTSLLNPGLVITTDRMGI---SREPGTSSTSNLSSTSHER 8332

Query: 725  ----ESSQSSQDSQPVVH-VIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKAL 779
                E +  ++D QP  H  + + R   S HE     S + +  D  SE+  ATS +   
Sbjct: 8333 LTTLEDTVDTEDMQPSTHTAVTNVRTSISGHE-----SQSSVLSD--SETPKATSPMGTT 8385

Query: 780  LELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSI-AVVESELVAEYITT 838
              + +T+V            I +   +    +T   R +  S  I +  E   V   + +
Sbjct: 8386 YTMGETSVSISTSDFFETSRIQIEPTS---SLTSGLRETSSSERISSATEGSTVLSEVPS 8442

Query: 839  ERTDEGTEVAFPLLVSHR----SQPQQ---PSQPQRTLLQHVAQSQTATQTSVVVKSIPA 891
              T   TEV+   ++S R    S P Q           +  ++ S   T+++    +I  
Sbjct: 8443 GAT---TEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIET 8499

Query: 892  SSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQT-GLFYRSAL--TQSQS 948
             SPGA +       +S T F   +    +      EM TL  +T G     +L   +  S
Sbjct: 8500 GSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEAS 8559

Query: 949  AKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQ 1008
            +    LS P +  T         F T       L         P    L++   K T + 
Sbjct: 8560 SVSSSLSSPAMTSTSF-------FST-------LPESISSSPHPVTALLTLGPVKTTDML 8605

Query: 1009 QEQAQPK----PDVQHTQHPMVA-----KDRQ------------LPTLM---AQPPQTVV 1044
            +  ++P+    P++  T   ++A     KDR+            + T++     P   + 
Sbjct: 8606 RTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLA 8665

Query: 1045 QVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVT 1104
             ++  K T  +       N       P  P++ M+ P SS      ++     T  ++  
Sbjct: 8666 DLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATER 8725

Query: 1105 KITFEGRQPPTVTKI--TGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTN 1162
              +  G      TK+  T   S+ + ++P     P Q++    +S      +      T 
Sbjct: 8726 SASLSGMPTGATTKVSRTEALSLGRTSTP----GPAQSTISPEISTETITRISTPLTTTG 8781

Query: 1163 VEHMIVDPPKKALATS------MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPST 1216
               M + P       S      + T    S P TH   +   + +P           P  
Sbjct: 8782 SAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTH---SAATHRSPHSGMTTPMSRGPED 8838

Query: 1217 VG--SSLTTRKIDPPA 1230
            V   S  +  K  PP+
Sbjct: 8839 VSWPSRPSVEKTSPPS 8854



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 189/949 (19%), Positives = 330/949 (34%), Gaps = 152/949 (16%)

Query: 76    LTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAE 135
             +T   H++S     S  +I    ++P +   +   A T    A++ +    + +   P +
Sbjct: 10255 VTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGD 10314

Query: 136   TGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCS 195
                        T   S P+STPVP  S     +     PA + +   S +T Y    S  
Sbjct: 10315 ATLS-------TIAESLPSSTPVPFSSSTFTTTDSSTIPALHEIT-SSSATPYRVDTSLG 10366

Query: 196   DEDEKPRKR----------RRTNSSSSSPVVLKEVPKAVV--PVSKTITVPVSGS--PKM 241
              E      R           +   +SSSP++   + ++V    V+    VP   +   + 
Sbjct: 10367 TESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRT 10426

Query: 242   SNIMQSIA-------------------NSLPP------HMSPVKITFTKPSTQTTNTTTQ 276
               IM+ I                     S  P      H    K   T  +   T TT  
Sbjct: 10427 DGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTAL 10486

Query: 277   KVIIVTTSPSSTFVPNI--LSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQS---SLV 331
             K     T  +S + P +  L+  +    +   +PT ++ +T    P V   + S   SL 
Sbjct: 10487 KTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLG 10546

Query: 332   SNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVS 391
             + +S+    +TPS        TA + S      S V Q +  S+ +  +T      S V 
Sbjct: 10547 AETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTT-----ASWVI 10601

Query: 392   APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQ-----PSPVSHQQQPQQSPL------ 440
              P + +    K        +L  V        A      P+ +S  +    +PL      
Sbjct: 10602 HPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGT 10661

Query: 441   -PPGIKPTI---QIKQESGVKIITQQVQPSKILPK-------------PVTATLP---TS 480
                   PT+     + E+    +T   + S  +P+             P  AT P   TS
Sbjct: 10662 DTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETS 10721

Query: 481   SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII 540
             S  PIM VS     + T  VT+ +GT    T PT++ S G         T+ +  + S I
Sbjct: 10722 SAIPIMTVSPGAEDLVTSQVTS-SGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAI 10780

Query: 541   TVVPKSLATLGGKIISSNIVS-GTTTKITTIPMTSKPN--VIVVQKTTGKGTTIQGLP-- 595
                  +++    ++++S + S    T  T   +T+ P      V   T    T   +P  
Sbjct: 10781 PT--STISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWT 10838

Query: 596   -------GKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPA 648
                      +   ++  + G ++   VPT   P + T    +   +VT  + + ST  P 
Sbjct: 10839 TSIFFHSKSDTTPSMTTSHGAESSSAVPT---PTVSTEVPGVVTPLVTSSRAVISTTIPI 10895

Query: 649   AKIIP-----TKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGN 703
               + P     T  +    G+      P P    +  V      LVT +    S       
Sbjct: 10896 LTLSPGEPETTPSMATSHGEEASSAIPTPTV--SPGVPGVVTSLVTSSRAVTSTTIPILT 10953

Query: 704   SSIQEGKEEPQNYTDSSSSSTESSQSSQDSQP--VVHVIASRRQDWSEHEIAM------- 754
              S+ E +  P   T   + +  +  +     P  V  ++AS R   S     +       
Sbjct: 10954 FSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEP 11013

Query: 755   ETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLES-----KPRQPTIDLSQMAVPI 809
             ET+P++     +S    A+ST+  +       V   + S         PT+ LS   +  
Sbjct: 11014 ETTPSM----ATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELET 11069

Query: 810   QMTQEKRHSPE------SPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQ-QP 862
               +    H  E      +P+++   S +V   +T+ R    T +  P+L    S+P+  P
Sbjct: 11070 TPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTI--PILTLSSSEPETTP 11127

Query: 863   SQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIM--QQALSSHT 909
             S            +    + S  V ++    PG +T ++   +A++S T
Sbjct: 11128 SM----------ATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTT 11166



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 184/891 (20%), Positives = 328/891 (36%), Gaps = 130/891 (14%)

Query: 65   AEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTA-FTVTANAVANAA 123
            +++  A+N++       N    + +S  S +   LV  +P  V  T  +  T++ V+ ++
Sbjct: 4718 SKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSS 4777

Query: 124  IQHNASLPVPAETG-SKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLP 182
            +  ++ +    +   S E V  S  S ++T     V S +   +++  P+    N VV  
Sbjct: 4778 VLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSI---NTVVTN 4834

Query: 183  SGSTVYV----KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGS 238
             G+T        +VS   E  K      T S+     + + +PK+            S +
Sbjct: 4835 VGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLT 4894

Query: 239  PKM--SNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSK 296
            PK+  ++I Q I +S          T T P  + T  TT+      TS SST  P     
Sbjct: 4895 PKLRETSISQEITSSTE--------TSTVPYKELTGATTEVSRTDVTSSSSTSFPG---- 4942

Query: 297  SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356
              + + V+  + T      +  P +  +A  +        G++S       +T  +    
Sbjct: 4943 -PDQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGPHGATSQ------DTFTMDPSN 4995

Query: 357  SSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQ 416
            ++  + + S +  G S   +    +R+P   S  S P+      P     SP        
Sbjct: 4996 TTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMT----- 5050

Query: 417  QQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT 476
              T   ++   P      P  S L  G+           VKI    +  +++  +PVT++
Sbjct: 5051 --TPSLISSTLPEDKLSSPMTSLLTSGL-----------VKIT--DILRTRL--EPVTSS 5093

Query: 477  LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536
            LP  S++   +++++     TK +     T+ T  +   S       A   + T   TT 
Sbjct: 5094 LPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQ 5153

Query: 537  GSIITVV----PKSLATLGGKIISSNIVSGTTTKIT-------TIPMTSKP---NVIVVQ 582
              I T V    P +   + G   ++NI    T  +T       T   +S P   + ++ +
Sbjct: 5154 MVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSK 5213

Query: 583  KTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP----TGAKPAILTA---TRPITKMIV 635
              TG  T +    G N  + +     +K+  TVP    TG  P + T+   T+     I 
Sbjct: 5214 VPTGTITEVSS-TGVNSSSKISTPDHDKS--TVPPDTFTGEIPRVFTSSIKTKSAEMTIT 5270

Query: 636  TQ---PKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATV-------VSEQTR 685
            TQ   P+    +  P    + T     Q G    + +  P +   T+       VS  T 
Sbjct: 5271 TQASPPESASHSTLP----LDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTT 5326

Query: 686  QLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQ 745
              V ET            SS+      P   + S  SST          PV         
Sbjct: 5327 PPVEET------------SSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVT-------- 5366

Query: 746  DWSEHEIAMETSPTIIYQDV--SSESQSATST---IKALLELQQTTVKEKLESKPRQPTI 800
                   A+ TS  +   DV  ++  +S TS+   + ++   +  T K+   ++      
Sbjct: 5367 -------ALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMH-- 5417

Query: 801  DLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPL-LVSHRSQP 859
              +  AV    T    H  +S  +A  E+      ++T  T   T V+     +S  +Q 
Sbjct: 5418 HSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQI 5477

Query: 860  QQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASS---PGAITHIMQQALSS 907
            Q  ++P  +L   + +S T+ +TS   ++  A S    GAIT   +  +SS
Sbjct: 5478 Q--TEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISS 5526



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 234/1213 (19%), Positives = 406/1213 (33%), Gaps = 185/1213 (15%)

Query: 129  SLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS----GSIAT----------VKSPRPASP 174
            S PVP    +     YS  S +S  ++ PV S    G   T          V S  P++ 
Sbjct: 5928 SSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSAS 5987

Query: 175  ASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSS--SPVVLKEVPKAVVPVSKT-- 230
            + +  +L S ++   +++  S E+        TNS     S V +   P    P   T  
Sbjct: 5988 SFSGEILTSEASTNTETIHFS-ENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGS 6046

Query: 231  ------ITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTS 284
                  ++    GSP+  N+ +   + L P +          ST  +NT    V +   +
Sbjct: 6047 MMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAAT 6106

Query: 285  PSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPS 344
              S             A VT   PT + AS          +++S  +S  +S S S++P 
Sbjct: 6107 EVSR------------AEVTYYDPTFMPASAQ--------STKSPDISPEASSSHSNSP- 6145

Query: 345  PIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404
            P+  +   T    + PS V S     + TS I   S   PS ++                
Sbjct: 6146 PLTISTHKTIATQTGPSGVTSLGQLTLDTSTIA-TSAGTPSART---------------- 6188

Query: 405  QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQ---PQQSPL-----PPGIKPTIQIKQESGV 456
            Q     +   V       V + SP S ++      Q+PL     P  +  T+Q    S +
Sbjct: 6189 QDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSL 6248

Query: 457  KIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVS 516
              +T        +P P  A + T  ++ +  V+ +   +   L T+    +AT    T+ 
Sbjct: 6249 VSVTS-------VPTPTLAKI-TDMDTNLEPVTRSPQNLRNTLATS----EATTDTHTMH 6296

Query: 517  PSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKP 576
            PSI    A  G  +   + +    TV P S        +     SG +   T++P +S  
Sbjct: 6297 PSINTAVANVGTTS---SPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAM 6353

Query: 577  NVIVVQKTTG------KGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI 630
              I  + T        + +T Q +   +  +T+     +K      T      LT++   
Sbjct: 6354 KKIESETTFSLIFRLRETSTSQKIGSSSDTSTVF----DKAFTAATTEVSRTELTSSSRT 6409

Query: 631  TKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP--------VTFQATVVSE 682
            +     +P     T   +  ++ T     +  +  +  +  P        +T+  ++ + 
Sbjct: 6410 SIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTS 6469

Query: 683  Q--TRQLVTETLQQ------ASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQ 734
            Q  T   +T    Q       SRV E        G   P     SSSSS  S  +     
Sbjct: 6470 QAGTHSAMTHGFSQLDLSTLTSRVPE-----YISGTSPPSVEKTSSSSSLLSLPAITSPS 6524

Query: 735  PVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESK 794
            PV   +   R     H  ++ TS  +   D+ +   S    + +      TT ++  +++
Sbjct: 6525 PVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTE 6584

Query: 795  PRQPTIDLSQMAVPIQMTQEKRHS--PESPSIAVVESELVAEY----------------I 836
               P+ +++   V    ++++ +S  P       V S +V  +                I
Sbjct: 6585 KMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEI 6644

Query: 837  TTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGA 896
            T    +    +A  L  +  SQ    S  +  +L  +    T T  + V  S   S PG 
Sbjct: 6645 TRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGP 6704

Query: 897  ITHIMQQALSSH-----------------TAFTKHSEELGTEEGEVEEMDTLDPQ----- 934
                    +S+                  T  T+    LG+       +DT         
Sbjct: 6705 DHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGT 6764

Query: 935  ----TGLFYRSALTQSQSAKQQKLS---QPPLEQTQLQ-------VKTLQCFQTKQKQTI 980
                T  F  S +T   +   + LS    P +E+T            T     +   +TI
Sbjct: 6765 HSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTI 6824

Query: 981  HLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPP 1040
            H     +   L   P L +    L    +      P++  T H ++  D     + A  P
Sbjct: 6825 HTTPSPMTSLLT--PSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHP 6882

Query: 1041 QTVVQVLAVKTTQQLPKLQQ---APNQPKIYVQPQTPQSQM-------SLPASSEKQTAS 1090
             T      V+TT      Q    A ++      P    S M       S+  SSE     
Sbjct: 6883 STSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIK 6942

Query: 1091 QVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDIL 1150
            +     +T G   T I+ +     T T I   S VP  T+   S + + +S +T++    
Sbjct: 6943 RESTYSLTPGLRETSIS-QNASFSTDTSIV-LSEVPTGTTAEVSRTEVTSSGRTSIPGPS 7000

Query: 1151 KMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRES 1210
            + +++       +  +   P     A   +  + G   ST      +  ST + Q    S
Sbjct: 7001 QSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHS 7060

Query: 1211 CSSPSTVGSSLTT 1223
              +     S +TT
Sbjct: 7061 TLTQRFPHSEMTT 7073



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 247/1206 (20%), Positives = 426/1206 (35%), Gaps = 177/1206 (14%)

Query: 84   SGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVC 143
            S P S    +++     PL P L   +   V  +   +  +  + SL    E    EV  
Sbjct: 6056 STPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTY 6115

Query: 144  YSYT------STTSTPTSTPVPSGS--------IATVKSPRPASPASNVVVL-------- 181
            Y  T       +T +P  +P  S S        I+T K+    +  S V  L        
Sbjct: 6116 YDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTS 6175

Query: 182  --------PSGST---VYVKSVSCSDED------EKPRKRRRTNS-SSSSPVVLKEVPKA 223
                    PS  T   V  ++ S  + D        P      NS SS +P+++   P  
Sbjct: 6176 TIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSP 6235

Query: 224  VV------PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTT--- 274
            V         S  ++V    +P ++ I     N  P   SP  +  T  +++ T  T   
Sbjct: 6236 VTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTM 6295

Query: 275  -----TQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV----IASTTQKPPVVITA 325
                 T    + TTS  + F   +   S  Y A + +V TS     I ST+      +  
Sbjct: 6296 HPSINTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKK 6355

Query: 326  SQS----SLV-------SNSSSGSSSSTPSPIPNT-------VAVTAVVSSTPSVVMSTV 367
             +S    SL+       ++   GSSS T +            V+ T + SS+ + +  T 
Sbjct: 6356 IESETTFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTE 6415

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
               +S      + T L +   L  +  + +A     H+ + +  L      T  Q    S
Sbjct: 6416 KPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHS 6475

Query: 428  PVSH-----QQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTS-S 481
             ++H           S +P  I  T     E      +    P+   P PV  TLP S  
Sbjct: 6476 AMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRP 6535

Query: 482  NSPIMVVS--SNGAIMTTKLVTT-----PTGTQATYTRPTVSPSI----GRMAATPGAAT 530
            +SP+ + S  ++G + TT ++ +     P     ++  PT S  I        +T  A T
Sbjct: 6536 SSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVT 6595

Query: 531  YVKTTSGSIITVVPKSLATLGGKIISSNIVS---GTTTKITTIPMTSKPNVIVVQKTTG- 586
             V TT+    +       +   K+ S  + S     T   T++P +S+   I ++ T   
Sbjct: 6596 NVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSL 6655

Query: 587  ----KGTTIQGLP----GKNVVTTLLNAGGEKTIQTVPTGAK------PAILTATRPI-T 631
                KGT+    P     K+ V   L  G  +T +T    ++      P   T +  I T
Sbjct: 6656 AHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDIST 6715

Query: 632  KMIVTQPKGIGSTVQPAAKIIP-TKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLV-T 689
            ++I + P  +G T      II  T    G   +    +     + +A   S  T++   +
Sbjct: 6716 EVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHS 6775

Query: 690  ETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSE 749
            E     ++  E  + +I      P +   +S SS+     +  S PV   +         
Sbjct: 6776 EMTTVMNKDPEILSWTI------PPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPS 6829

Query: 750  HEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ----TTVKEKLESKPRQPTIDLSQM 805
               ++ T   ++  D    S   T++    L        TT ++    +   P+   +  
Sbjct: 6830 PMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAAT 6889

Query: 806  AVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQ--PQQPS 863
             V    T    H  +S  +A  E       + T  T   T V+  + VS  +    ++ +
Sbjct: 6890 NVE---TTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKREST 6946

Query: 864  QPQRTLLQHVAQSQTA---TQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGT 920
                  L+  + SQ A   T TS+V+  +P  +   ++   +   S  T+    S+    
Sbjct: 6947 YSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSR-TEVTSSGRTSIPGPSQSTVL 7005

Query: 921  EEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQP-PLEQTQLQVKTLQCFQTKQKQT 979
             E     M      T LF  ++ T ++SA+    +Q  P   T     TL    TK +  
Sbjct: 7006 PEISTRTM------TRLF--ASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAK 7057

Query: 980  IHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQP 1039
             H     L  + P        H ++T L    ++   D+     P +     LP+L++ P
Sbjct: 7058 TH---STLTQRFP--------HSEMTTL---MSRGPGDMSWQSSPSLENPSSLPSLLSLP 7103

Query: 1040 ----PQTVVQVLAVK-TTQQLPKLQQAPNQP-----KIYVQPQ-TPQSQMSLPASSEKQ- 1087
                P  +   L V  ++  LP      + P      ++  P+    S   L  +S+++ 
Sbjct: 7104 ATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERL 7163

Query: 1088 ------TASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQAS 1141
                  T ++   P     +S  +I   G + P  +     S   K TSP+  I+  Q  
Sbjct: 7164 TTGKDTTNTEAVHPSTNTAASNVEIPSSGHESP--SSALADSETSKATSPM-FITSTQED 7220

Query: 1142 EKTAVS 1147
               A+S
Sbjct: 7221 TTVAIS 7226



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 262/1319 (19%), Positives = 453/1319 (34%), Gaps = 205/1319 (15%)

Query: 42    TKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVP 101
             T    +L G   ++L+ S      E     +   +T +    SG    S  SI       
Sbjct: 10070 TSLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKA 10129

Query: 102   LMPRLVPQTAF--TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVP 159
               P   P +    +++ +  AN       + P    T        S  +++ TPT+TP  
Sbjct: 10130 TYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSS 10189

Query: 160   SGSIATVKSPRPA------------SPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
              GS   ++S +               PAS    +P        +     E         +
Sbjct: 10190 PGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPES 10249

Query: 208   NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHM-----SPVKIT 262
               + S       +   ++P ++TI+   +  P +S  M S A +  P       SP   T
Sbjct: 10250 RFTMSVTESTHHLSTDLLPSAETISTG-TVMPSLSEAMTSFATTGVPRAISGSGSPFSRT 10308

Query: 263   FTKPSTQTTNTTTQKVIIVTTSP--SSTFVPN------ILSKSHNYAAVTKLVPTSV--I 312
              + P   T +T  + +   T  P  SSTF          L +  + +A    V TS+   
Sbjct: 10309 ESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTE 10368

Query: 313   ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
             +STT+   V++    S+L ++S  G +SS  SPI +T         T SV + TV    S
Sbjct: 10369 SSTTEGRLVMV----STLDTSSQPGRTSS--SPILDT-------RMTESVELGTV---TS 10412

Query: 373   TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
                +   STRL     ++   T+I  +   +    P +       QT    A P  +   
Sbjct: 10413 AYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVK-----GPQTSTSPASPKGLHTG 10467

Query: 433   QQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSN 491
                +       +K  T  +K  S   + T    P+     P+ A++  +S  P  ++ + 
Sbjct: 10468 GTKRMETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITT 10527

Query: 492   GAIM-----TTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
               +      TT  + T  G + +   P  +PS+    +   A+  + + SG+  + V ++
Sbjct: 10528 PYVFPDVPETTSSLATSLGAETSTALPRTTPSVFNRESETTAS--LVSRSGAERSPVIQT 10585

Query: 547   LATLGGKIISSNIVSGTTTKITTIPMTSK--PNVI------VVQKTTGKGTTIQGLPGKN 598
             L     +       S       TIP  SK  PN        V    T  G  +      N
Sbjct: 10586 LDVSSSE--PDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTN 10643

Query: 599   V-------VTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651
             +       +T L+   G  T  T PT  K    T TR      +T P    ST+    + 
Sbjct: 10644 ISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTW---LTHPAETSSTI---PRT 10697

Query: 652   IPTKIVYGQQGKTQVLIKPKPVTFQA---TVVSEQTRQLVTETLQQASRVAEAGNSSIQE 708
             IP    +       +   P   T  A     VS     LVT      S+V  +G      
Sbjct: 10698 IPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVT------SQVTSSG------ 10745

Query: 709   GKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSE 768
                     TD + +    + S  + + +  ++         H  A +TS  I    +S  
Sbjct: 10746 --------TDRNMTIPTLTLSPGEPKTIASLVT--------HPEA-QTSSAIPTSTISPA 10788

Query: 769   SQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQE---------KRHSP 819
                  +++   L  + +T    L + P +P   +S +  P Q +              S 
Sbjct: 10789 VSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSD 10848

Query: 820   ESPSIAVVE-SELVAEYITTERTDEGTEVAFPLLVSHRS-----------QPQQPSQPQR 867
              +PS+     +E  +   T   + E   V  PL+ S R+            P +P     
Sbjct: 10849 TTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPS 10908

Query: 868   TLLQHVAQSQTATQTSVVVKSIP------ASSPGAITH----IMQQALSSHTAFTKHSEE 917
                 H  ++ +A  T  V   +P       +S  A+T     I+  +L         +  
Sbjct: 10909 MATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATS 10968

Query: 918   LGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQK 977
              GTE G    + T+ P+      S +  S++     L  P L  +  + +T     T   
Sbjct: 10969 HGTEAGSA--VPTVLPEVPGMVTSLVASSRAVTSTTL--PTLTLSPGEPETTPSMATSHG 11024

Query: 978   QTIHLQADQLQHKLP----------------QMPQLSIRHQKL--TP-------LQQEQA 1012
                      +  ++P                 +P L +   +L  TP        +   A
Sbjct: 11025 AEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSA 11084

Query: 1013  QP----KPDVQHTQHPMVAKDRQLP-------TLMAQPPQTVVQVLAVKTTQQLPKLQQA 1061
              P     P V     P+V   R +        TL +  P+T   +      +        
Sbjct: 11085 VPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVE-------- 11136

Query: 1062  PNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKIT---FEGRQPPTVTK 1118
              +   + V P+ P    SL  SS   T++ +  P +T  S   + T       +   ++ 
Sbjct: 11137 ASSAVLTVSPEVPGMVTSLVTSSRAVTSTTI--PTLTISSDEPETTTSLVTHSEAKMISA 11194

Query: 1119  ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
             I   +  P +   VTS+     SE +A S++   S     ID+ V H   +        +
Sbjct: 11195 IPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLT 11254

Query: 1179  MLTGEAGSLPSTHMVVA---GMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPAT 1234
             + TGE    P T++ +      ++ST  +   R S S   T+ S++T+ + +  +  +T
Sbjct: 11255 VSTGE----PFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAIST 11309



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 226/1128 (20%), Positives = 393/1128 (34%), Gaps = 138/1128 (12%)

Query: 84   SGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVC 143
            S  + +S W+ E        P+    T +  T+ ++       + S+  P  T    VV 
Sbjct: 511  SSTSKASSWTSESTAQQFSEPQ---HTQWVETSPSMKTERPPASTSVAAPITTSVPSVVS 567

Query: 144  YSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK 203
               T  TS+     +   S  T+     A P ++   +P+G ++   S +   +      
Sbjct: 568  GFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLL 627

Query: 204  RRRTNSSSSS---PVVLKEVPKAVVP-VSKT-------------ITVPVSGSPKMSNIMQ 246
             R T SS +S    +    VP +V P VSKT              T+  S  P+ S++  
Sbjct: 628  TRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQS 687

Query: 247  SI-----------ANSLPPHMSPV--KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNI 293
            S             N+  P  SP       TK ST     ++  V+    S +STF    
Sbjct: 688  SAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTF---- 743

Query: 294  LSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSST-----PSPIPN 348
               SH+ A  +    T  I++ T+    V+++   S  + S     ++T     PSP   
Sbjct: 744  ---SHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGE 800

Query: 349  TVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVS---APTQILAQFPKQHQ 405
              A + +  ST S   +       T  +   S+  PS  SL S     T   +  P  H 
Sbjct: 801  ETAGSVLTLST-SAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHL 859

Query: 406  QSPKQQLYQVQQQTQQQVAQP-SPVSHQQQPQQS-PLPPGIKPTIQIKQESGVKIITQQV 463
             +  +   + ++ +   V+QP + VS  +    S  +P  + PT+        +  +  +
Sbjct: 860  FTSGE---ETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHL 916

Query: 464  QPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMA 523
                     V+    TSS S   V +S G+ +      T T T +   R T + S    +
Sbjct: 917  ---------VSELRATSSTS---VTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQS 964

Query: 524  AT-PGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTT------------TKITTI 570
             T P  +   KT   S  T V  S  +L   ++ S   S  T            T I T 
Sbjct: 965  TTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTT 1024

Query: 571  PMTSKPNVIVVQKTT---GKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTAT 627
              T+ P  + V  T    GKG   +G    + +     A  E ++    T AK ++  + 
Sbjct: 1025 ETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDF--TMAKESVSMSV 1082

Query: 628  RPITKMIVTQPKGIGSTVQ-------PAAKIIPTKIVYGQQGKTQVLI---------KPK 671
             P   M        G T Q           +   +I   + G +  L           P 
Sbjct: 1083 SPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPD 1142

Query: 672  PVTFQAT----VVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESS 727
            P + ++T    + S  +      T+           S I +  E  +    +  S+T  +
Sbjct: 1143 PGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLT 1202

Query: 728  QSSQDSQPVVHVIASRRQDWSEHEIAMETS----PTIIYQDVSSESQS------ATSTIK 777
             S+  +   +        D      ++E S    PT+     S+ + S      A+S   
Sbjct: 1203 PSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESP 1262

Query: 778  ALLELQQTTVKEKLESKPRQ-PTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELV---A 833
            + ++L   +V +     P   P+I+        +M      SPE  +     +       
Sbjct: 1263 STIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPT 1322

Query: 834  EYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASS 893
             YITT    + +        S R+     + P+       A S +   +S    + PA+ 
Sbjct: 1323 TYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATK 1382

Query: 894  PGAITHIMQQALSSHTAFTKHSE-----ELGTEEGEVEEMDTLDPQTGLFYRSALTQSQS 948
               IT   + +   H  +TK +E     E  +  G V  +    P  G    S L  +  
Sbjct: 1383 AWTITDTTEHSTQLH--YTKLAEKSSGFETQSAPGPVSVVIPTSPTIG---SSTLELTSD 1437

Query: 949  AKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQ 1008
               + L   P EQT + +       T   + +      +      M   +I     TP  
Sbjct: 1438 VPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTP-S 1496

Query: 1009 QEQAQPKPD---VQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKT--TQQLPKLQQAPN 1063
             E ++ + D   +++T    + +   + +L      T V +  + T  T  +    QA +
Sbjct: 1497 HELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQD 1556

Query: 1064 QPKIYVQP----QTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKIT 1107
                 + P    Q+ + Q S+PAS+     ++V   + TQG S ++ T
Sbjct: 1557 TLSATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEAT 1604



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 219/1103 (19%), Positives = 385/1103 (34%), Gaps = 178/1103 (16%)

Query: 108  PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI--AT 165
            P     VT    A++A   +++LPV +E               ST TS  VP+ S+  A 
Sbjct: 4533 PSINKAVTNMGTASSAHVLHSTLPVSSEP--------------STATSPMVPASSMGDAL 4578

Query: 166  VKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV 225
                 P S  +++   P+ S    +  + + ++           S+ S   + E  K  V
Sbjct: 4579 ASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEV 4638

Query: 226  PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNT-TTQKVIIV--- 281
            P      +P          + S+A+S   +  P+ I+    +TQT ++  T K+ +    
Sbjct: 4639 PSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDT 4698

Query: 282  TTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSS 341
            +T  +S   P+++++   ++ +T  +   V   +   PP    AS       S S  +  
Sbjct: 4699 STLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEAS-------SPSSQAPV 4751

Query: 342  TPSPIPNTVAVTAVVSSTPS-VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQF 400
              + +P++VA T    ST S V MS+V   +++S +K A     S +++ S+P       
Sbjct: 4752 LVTTLPSSVAFTPQWHSTSSPVSMSSV---LTSSLVKTAGKVDTSLETVTSSP------- 4801

Query: 401  PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIIT 460
                         Q    T   ++  S  +   +       P I   +     +G    +
Sbjct: 4802 -------------QSMSNTLDDISVTSAATTDIETTH----PSINTVVTNVGTTGSAFES 4844

Query: 461  QQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIG 520
                 +   P+P   T P                     VTT     +T    T+S SI 
Sbjct: 4845 HSTVSA--YPEPSKVTSPN--------------------VTT-----STMEDTTISRSIP 4877

Query: 521  RMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIV 580
            + + T    T  +TTS    ++ PK   T     IS  I S T T  +T+P         
Sbjct: 4878 KSSKT--TRTETETTS----SLTPKLRET----SISQEITSSTET--STVPYKELTGATT 4925

Query: 581  -VQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPK 639
             V +T    ++    PG +  T  L+   E               T TR  T  I+T+  
Sbjct: 4926 EVSRTDVTSSSSTSFPGPDQSTVSLDISTE---------------TNTRLSTSPIMTESA 4970

Query: 640  GIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL----VTETLQQA 695
             I  T Q           +G   +    + P   T QA + S  T       VT  + + 
Sbjct: 4971 EITITTQTGP--------HGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRI 5022

Query: 696  SRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSS-----QDSQPVVHVIASRRQDWSEH 750
             +     +    +    P ++  S + +T S  SS     + S P+  ++ S        
Sbjct: 5023 PQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGL------ 5076

Query: 751  EIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQ 810
             + +        + V+S   + +ST   +L     T K+  ++K   P+I+  +  V   
Sbjct: 5077 -VKITDILRTRLEPVTSSLPNFSSTSDKIL----ATSKDSKDTKEIFPSINTEETNVKAN 5131

Query: 811  MTQEKRHSPESPSIAVVESE----LVAEYITTERTDEGTEVAFPLLVSHRSQ--PQQPSQ 864
             +  + HSP     A+ +SE         ITT   D     + P+  S  +    ++P+ 
Sbjct: 5132 NSGHESHSP-----ALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTY 5186

Query: 865  PQRTLLQHVAQSQTA---TQTSVVVKSIPASSPGAITHIMQQALSSHTAFT-----KHSE 916
                 L+  + SQ +   T TS ++  +P    G IT +    ++S +  +     K + 
Sbjct: 5187 FLTPRLRETSTSQESSFPTDTSFLLSKVPT---GTITEVSSTGVNSSSKISTPDHDKSTV 5243

Query: 917  ELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLE------QTQLQVKTLQ 970
               T  GE+  + T   +T     +  TQ+   +    S  PL+      Q        Q
Sbjct: 5244 PPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQ 5303

Query: 971  CFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDR 1030
             F   +  T+          +   P        ++ L    A   P    +  P      
Sbjct: 5304 GFPYSEVTTLMGMGPGNVSWMTTPPVEET--SSVSSLMSSPAMTSPSPVSSTSPQSIPSS 5361

Query: 1031 QLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKI-YVQPQTPQSQMSLPASSEKQTA 1089
             LP         V     + TT         PN   I + +P T +      A+    T 
Sbjct: 5362 PLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTN 5421

Query: 1090 SQVEQPIITQG------SSVTKITFEGRQPP--TVTKITGGSSVPKLTSPVTSISPIQAS 1141
            + V   + T G      SSV   +   +  P  + T   G +SV   T  ++  + IQ  
Sbjct: 5422 TAVTN-VGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTE 5480

Query: 1142 EKTAVSDILKMSLMEAQIDTNVE 1164
               ++S  L+ S    +  +  E
Sbjct: 5481 PTASLSPRLRESSTSEKTSSTTE 5503



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 213/1185 (17%), Positives = 425/1185 (35%), Gaps = 173/1185 (14%)

Query: 104   PRLVPQTAFTVTANAVANAAIQHNASLPVPAE-TGSKEVVCYSYTSTTSTPTSTPVPSGS 162
             P  VP  A T      +   +  ++  P P + T S+++     T  +++P  T     +
Sbjct: 9019  PSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMT 9078

Query: 163   IATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPK 222
             I T ++  P + +   + L + +T    + S + +     +     S +   V     P 
Sbjct: 9079  ITT-QTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPS 9137

Query: 223   AVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVT 282
                  S + ++        S +  ++ +S+     PV    T    +TT     +++  +
Sbjct: 9138  VEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTT-----ELLGTS 9192

Query: 283   TSPSSTFVPNILSKSHNYAAVT-------KLVPTSVIAST-TQKPPVVITASQSSLVSNS 334
             + P ++  PN+ S S    A+T       KL  T+V+ S  T + P  + A   +  + S
Sbjct: 9193  SEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATS 9252

Query: 335   SSGSSSSTPSPIPNTVAVTAVVSSTP---------------------------------- 360
             S G +  T          T V++STP                                  
Sbjct: 9253  SMGITYPTGD--------TNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATE 9304

Query: 361   -SVVMSTVAQGVS-----TSAIKMASTRLPSP-KSLVSAPTQI----------------- 396
              S V+S+V  G +     T AI  + T +P P +S +S+ T +                 
Sbjct: 9305  KSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTD 9364

Query: 397   LAQFPKQHQQ-SPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESG 455
             +A  PK     +  Q  + +   +          + Q+ PQ     P  +    +   S 
Sbjct: 9365  MAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSP 9424

Query: 456   VKIITQQVQPSKILPKPVTATLP-------TSSNSPIMVVSSNGAIM--TTKLVTT---P 503
             + +       S +    VT+  P       +S +SP+ V S   +IM   T ++     P
Sbjct: 9425  LSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEP 9484

Query: 504   TGTQATYTRPTVSPSIGRMAATP----------GAATYVKTTSGSIITVVPKSLATLGGK 553
               T A     T   S+    AT            AA++V+TTS +          +   K
Sbjct: 9485  ETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTK 9544

Query: 554   IISSNIVSGT---TTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEK 610
             +IS  + S +       TT+P +S    I ++  +     ++       +T+  +     
Sbjct: 9545  VISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITS--STETST 9602

Query: 611   TIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKP 670
              +  +P+GA P +       T+++ +    I    Q    +  +  V  +   + ++ + 
Sbjct: 9603  VLYKMPSGATPEVSR-----TEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTES 9657

Query: 671   KPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSS 730
               +T             VT  L  +       +S++ +G     ++++ ++  +   +S 
Sbjct: 9658  AEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQG----LSHSEMTNLMSRGPESL 9713

Query: 731   QDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL--ELQQTTVK 788
               + P    + + R   S   + + TS + +   +   S S+   + +L+   L +TT  
Sbjct: 9714  SWTSP--RFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEV 9771

Query: 789   EKLESKPR---QPTIDLSQMAVP----IQMTQEKRHSPESPSIAVVE-SELVAEYITTER 840
                 S+P+    P +  + + +P    I    EK H   + ++A V  S  V E  ++  
Sbjct: 9772  LDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVL 9831

Query: 841   TDEGTEVAFPLL---------VSHRSQP------QQPSQPQRTLLQHVAQSQTA------ 879
              D  T +  P +             S P      + P++P  +L     ++ T+      
Sbjct: 9832  ADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSI 9891

Query: 880   TQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFY 939
             T+TS V+  +P S+   ++  M + +SS+      S++       + E+ T    + +  
Sbjct: 9892  TETSAVLYGVPTSATTEVS--MTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMS 9949

Query: 940   RSALTQSQSAKQQKLSQPPLEQTQLQVKT-----LQCFQTKQKQTIHLQADQLQHKLPQM 994
              S      +   QK S     Q+ L + T      +   T   + +H +   L  + P+ 
Sbjct: 9950  EST---QMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPEN 10006

Query: 995   PQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQ 1054
             P        L   +   +     +  T  P V+      TL    P +   V ++  T  
Sbjct: 10007 PSWK---SSLFVEKTSSSSSLLSLPVTTSPSVSS-----TLPQSIPSSSFSVTSL-LTPG 10057

Query: 1055  LPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPP 1114
             + K      +P   + P    + + + A+SE  T ++   P  +   +VT +        
Sbjct: 10058 MVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHP--SSSMAVTNVGTTSSGHE 10115

Query: 1115  TVTKITGGSSVPKLTSPV-TSISPIQASEKTAVSDILKMSLMEAQ 1158
               + ++  S   K T PV T  S  + S  T++    + +  EA+
Sbjct: 10116 LYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPANFETTGFEAE 10160



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 113/478 (23%), Positives = 186/478 (38%), Gaps = 55/478 (11%)

Query: 63    HRAEVRRAVNDERLTTIAHNMS--GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVA 120
             H AE    V+   +   +H  S   P+  +   ++ R  VP     +P +   V  + V 
Sbjct: 11580 HPAETSTTVSGT-IPNFSHRGSDTAPSMVTSPGVDTRSGVPTTT--IPPSIPGVVTSQVT 11636

Query: 121   NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV 180
             ++A   + ++P    +  +     S  +   T T   VP   I TV S  P + AS V  
Sbjct: 11637 SSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVP---IRTVPSSEPDTMASWVTH 11693

Query: 181   LPSGSTVYVKSVSC---SDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSG 237
              P  ST   ++ S    S  D  P       + +SS V+    P A   V+  IT   S 
Sbjct: 11694 PPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQIT---SS 11750

Query: 238   SPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKS 297
                 S  + ++ +S P       +  T P T+T+ T           P+ST  P +   S
Sbjct: 11751 GAATSTTVPTLTHS-PGMPETTALLSTHPRTETSKTF----------PASTVFPQV---S 11796

Query: 298   HNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS 357
                A++T + P    A T+   P   T+S  +L+   +S    S P+  P   A TA +S
Sbjct: 11797 ETTASLT-IRPG---AETSTALPTQTTSSLFTLLVTGTSRVDLS-PTASPGVSAKTAPLS 11851

Query: 358   STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQ 417
             + P    ST+    + S   + +T L +  S     T  L         SP         
Sbjct: 11852 THPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTL-----TVSPAVSGLSSAS 11906

Query: 418   QTQQQVAQPSPVSHQQQPQQSPL-PPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTA- 475
              T  +    +  + +  P  + + PP    T+     +G    T  + PS++   P T+ 
Sbjct: 11907 ITTDKPQTVTSWNTETSPSVTSVGPPEFSRTV-----TGT---TMTLIPSEMPTPPKTSH 11958

Query: 476   ---TLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAAT 530
                  PT+     MV ++N  + TT   ++PT  + T T  T++ S+     TPG +T
Sbjct: 11959 GEGVSPTTILRTTMVEATN--LATTG--SSPTVAKTTTTFNTLAGSLFTPLTTPGMST 12012



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 113/534 (21%), Positives = 192/534 (35%), Gaps = 102/534 (19%)

Query: 133   PAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSV 192
             PAET +         S + + T+ PV      T   P  +S  S   + P  S +    V
Sbjct: 11495 PAETNTMVPRTTPKFSHSKSDTTLPVA----ITSPGPEASSAVSTTTISPDMSDLVTSLV 11550

Query: 193   SCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN-- 250
               S           T++S++ P  L E P      +  +T P   S  +S  + + ++  
Sbjct: 11551 PSSG----------TDTSTTFPT-LSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRG 11599

Query: 251   -----------------SLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNI 293
                               +P    P  I     S  T++ T     I T +PS       
Sbjct: 11600 SDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETT 11659

Query: 294   LSKSHNYAAVT------KLVPTS---VIASTTQKPPVVITASQSSLVSNSSSGSSSSTPS 344
              S + +    T      + VP+S    +AS    PP       S+ VS ++S  S S+P 
Sbjct: 11660 ASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPP-----QTSTPVSRTTSSFSHSSPD 11714

Query: 345   PIPNTVAVTAVVSSTPSVVMSTVAQGVS-------TSAIKMASTRLPSPKSLVSAP--TQ 395
               P  V  T+  +   S V++T++ G         TS+    ST +P+       P  T 
Sbjct: 11715 ATP--VMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETTA 11772

Query: 396   ILAQFPKQHQQS--PKQQLY-QVQQQTQQQVAQPSPVSHQQQPQQSP------------- 439
             +L+  P+       P   ++ QV + T     +P   +    P Q+              
Sbjct: 11773 LLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSR 11832

Query: 440   --LPPGIKPTIQIKQ---------ESGVKIITQQVQPSKILPKPVTAT---LPTSSNSPI 485
               L P   P +  K          E+   I T  +    +    + AT     TS+++  
Sbjct: 11833 VDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLT 11892

Query: 486   MVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545
             + VS   + +++  +TT      T      SPS+     + G   + +T +G+ +T++P 
Sbjct: 11893 LTVSPAVSGLSSASITTDKPQTVTSWNTETSPSV----TSVGPPEFSRTVTGTTMTLIPS 11948

Query: 546   SLAT-----LGGKIISSNIVSGTTTKITTIPMT-SKPNVIVVQKTTGKGTTIQG 593
              + T      G  +  + I+  T  + T +  T S P    V KTT    T+ G
Sbjct: 11949 EMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSP---TVAKTTTTFNTLAG 11999



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 222/1201 (18%), Positives = 418/1201 (34%), Gaps = 164/1201 (13%)

Query: 132  VPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVL-PSGSTVYVK 190
            VP ET  + V   S    + + + + +P+G+ +  KSP     A+  V L PS    +  
Sbjct: 3236 VPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTN 3295

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTIT-VPVSGSPKMSNIMQSIA 249
              S +     P   R++ ++ SS V L+       P +++IT      SP++ +    + 
Sbjct: 3296 LYSGT-----PGGTRQSLATMSS-VSLES------PTARSITGTGQQSSPELVSKTTGME 3343

Query: 250  NSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAV---TKL 306
             S+    +      T  S  T++   +  +   TSP+S  V ++  KS +       T  
Sbjct: 3344 FSMWHGSTGGTTGDTHVSLSTSSNILEDPV---TSPNS--VSSLTDKSKHKTETWVSTTA 3398

Query: 307  VPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPI--------PNTVAVTAVVSS 358
            +P++V+ +         + S     S++SS S  ++ S I         NT+ +T+   +
Sbjct: 3399 IPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQT 3458

Query: 359  TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418
            T  V + +  QG+ TS    +  +  S  S+                 SP   L  ++  
Sbjct: 3459 TSLVSLPSGDQGI-TSLTNPSGGKTSSASSVT----------------SPSIGLETLRAN 3501

Query: 419  TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478
                 +  +P +       SP             E  +  +T    P       ++ T+ 
Sbjct: 3502 VSAVKSDIAPTAGHLSQTSSP------------AEVSILDVTTAPTPG------ISTTIT 3543

Query: 479  TSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGS 538
            T   + I   + N  +  + + +TP   + T +  T  PS     A   + T    TS  
Sbjct: 3544 TMGTNSISTTTPNPEVGMSTMDSTPATERRTTS--TEHPSTWSSTAASDSWTVTDMTSNL 3601

Query: 539  IITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKN 598
             +   P +++T+                 TT  + S   +  +    G+ T I    G +
Sbjct: 3602 KVARSPGTISTMH----------------TTSFLASSTELDSMSTPHGRITVI----GTS 3641

Query: 599  VVTTLLNAGGEKT-IQTVPTGAKPAILTATRPIT------KMIVTQPKGIGSTVQPA--- 648
            +VT   +A   KT   T      P+  TA+ PI+      +M ++ P  + ++  P+   
Sbjct: 3642 LVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTE 3701

Query: 649  AKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQE 708
            A+ +P  +V      T    K  P T  +T + +    L  +T +  S  +    +S  +
Sbjct: 3702 AEDVPVSMVSTDHAST----KTDPNTPLSTFLFDSLSTLDWDTGRSLS--SATATTSAPQ 3755

Query: 709  GKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIA------------SRRQDWSEHEIAMET 756
            G   PQ  T  +  S  +SQ       +   +             SR    S+      T
Sbjct: 3756 GATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTST 3815

Query: 757  S-PTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEK 815
              PT          +SA +T+  +    +T   +    +  Q  +     A      +++
Sbjct: 3816 QLPTTTSAHPGQVPRSAATTLDVIPHTAKT--PDATFQRQGQTALTTEARATSDSWNEKE 3873

Query: 816  RHSPESPSIAVVESELVAEYITTERTDEGT------EVAFPLLVSHRSQPQQPSQPQRTL 869
            + +P +P I  + +  V+E    E T   +       +   L     S P   S P    
Sbjct: 3874 KSTPSAPWITEMMNS-VSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSP---- 3928

Query: 870  LQHVAQSQTATQTSVVVKSI-PASSPGAIT---HIMQQALSSHTAFTKHSEEL---GTEE 922
             + +A S++ T    +  S     + G +T   H     + +H+A +K +  +    T E
Sbjct: 3929 YERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTRE 3988

Query: 923  GEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHL 982
              +  M T          +   +S  A+ +  S   +E   +    +    T Q   I  
Sbjct: 3989 QAIVSMST----------TTWPESTRARTEPNSFLTIELRDVS-PYMDTSSTTQTSIISS 4037

Query: 983  QADQLQHKLPQMPQLSIRHQKLTPLQQE-QAQPKPDVQHTQ---HPMVAKDRQLPTLMAQ 1038
                   K P+    S +    + L Q  ++   P    T+    P + +   +   M  
Sbjct: 4038 PGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQT 4097

Query: 1039 PPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIIT 1098
             P     + A   T            P    Q  T   + +L +   + T+      +  
Sbjct: 4098 SPPGATSLSA--PTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEE 4155

Query: 1099 QGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQ 1158
              SS + +       P+   +T     P  T PVTS+     SE + +     MS +  +
Sbjct: 4156 TSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVF---LSETSGLGKTTDMSRISLE 4212

Query: 1159 IDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVG 1218
              T++   +     +AL+T   + +  ++  +         +T  +       + PS   
Sbjct: 4213 PGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKAT 4272

Query: 1219 SSLTTRKIDPPAVPATGQF--------MRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSS 1270
            S L T  I      +T  F          + +V Q   E S +++   A     +  H S
Sbjct: 4273 SPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVS 4332

Query: 1271 S 1271
            S
Sbjct: 4333 S 4333



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 236/1273 (18%), Positives = 443/1273 (34%), Gaps = 220/1273 (17%)

Query: 65   AEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAI 124
            A  +R    E+ T  +    GP  +S+ S            LVP  A T  +N +  +  
Sbjct: 4124 ATTQRFTYSEKTTLFS---KGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQG 4180

Query: 125  QHNASLPVPAETGSKEVVCYSYT---STTSTPTSTPVPSGSIATVKSPRPASPAS-NVVV 180
               +S P        E      T   S  S    T +P    +T         AS +   
Sbjct: 4181 HSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKA 4240

Query: 181  LPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPK 240
            +   +   V ++  +  +  P       S ++SP+V   +   +     T +  V GS +
Sbjct: 4241 IHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDI-----TSSTSVFGSSE 4295

Query: 241  MSNI--MQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSH 298
             + I  + S+   L            + ++Q  ++ T+   ++T   S     ++     
Sbjct: 4296 TTEIETVSSVNQGLQE----------RSTSQVASSATETSTVITHVSSGDATTHVTKTQA 4345

Query: 299  NYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS 358
             +++ T +       ++T     V T   +SL+   SSG            V +T     
Sbjct: 4346 TFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSG------------VTITTQTGP 4393

Query: 359  TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418
            T +          ST      +    +P  + S  T ++++ PK                
Sbjct: 4394 TGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPK---------------- 4437

Query: 419  TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478
                V+  SP S  +    S L P +  TI                       P T+TL 
Sbjct: 4438 ---DVSWTSPPSVAETSYPSSLTPFLVTTI----------------------PPATSTLQ 4472

Query: 479  ---TSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTT 535
               TSS      V ++G + TT ++ T         +   +PS   + AT  A T ++T 
Sbjct: 4473 GQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSPQNLNNPS-NEILATLAATTDIETI 4531

Query: 536  SGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLP 595
              SI   V     T  G   S++++       +T+P++S+P       +T     +    
Sbjct: 4532 HPSINKAV-----TNMGTASSAHVLH------STLPVSSEP-------STATSPMVPASS 4573

Query: 596  GKNVVTTLLNAGGEKT-IQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPT 654
              + + ++   G E T I+  PT +    LTA R     +    + + ST +  + II +
Sbjct: 4574 MGDALASISIPGSETTDIEGEPTSS----LTAGRKENSTL----QEMNSTTE--SNIILS 4623

Query: 655  KIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQ 714
             +  G   +   +  P   +F AT +          T  Q+++  +  + +       P 
Sbjct: 4624 NVSVGAITEATKMEVP---SFDATFI---------PTPAQSTKFPDIFSVASSRLSNSPP 4671

Query: 715  NYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATS 774
                +  ++T++  S                  S+  +A++TS        + E+ + T 
Sbjct: 4672 MTISTHMTTTQTGSSGAT---------------SKIPLALDTS--------TLETSAGTP 4708

Query: 775  TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAE 834
            ++     + +     K+ +       D+SQ   P    Q++  SP S +  +V       
Sbjct: 4709 SV-----VTEGFAHSKITTAMNNDVKDVSQTNPPF---QDEASSPSSQAPVLV------- 4753

Query: 835  YITTERTDEGTEVAF-PLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASS 893
                  T   + VAF P   S  S     S    +L++   +  T+ +T   V S P S 
Sbjct: 4754 ------TTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLET---VTSSPQS- 4803

Query: 894  PGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQK 953
                   M   L   +  +  + ++ T    +  + T    TG  + S  T S   +  K
Sbjct: 4804 -------MSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSAYPEPSK 4856

Query: 954  LSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ 1013
            ++ P +  + ++  T+     K  +T   + +      P++ + SI  Q++T   +    
Sbjct: 4857 VTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSI-SQEITSSTETSTV 4915

Query: 1014 PKPDVQHTQHPMVAKD--RQLPTLMAQPPQTVVQV-LAVKTTQQLPKLQQAPNQPKIYVQ 1070
            P  ++      +   D      T    P Q+ V + ++ +T  +L          +I + 
Sbjct: 4916 PYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESAEITIT 4975

Query: 1071 PQT----PQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVP 1126
             QT      SQ +        T        +T G S   +T    + P     T   SV 
Sbjct: 4976 TQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVD 5035

Query: 1127 KLTSPVTSISPIQASEKTAVSDIL---KMSLMEAQIDTNVEHMIVDPPKKALATSMLTGE 1183
            K +SP + +S    +  + +S  L   K+S     + T+    I D  +  L    +T  
Sbjct: 5036 KTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRL--EPVTSS 5093

Query: 1184 AGSLPSTHMVVAGMANSTPQQQKCRESCSSPST-VGSSLTTRKIDPPAV------PATGQ 1236
              +  ST   +   +  +   ++   S ++  T V ++ +  +   PA+       AT Q
Sbjct: 5094 LPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQ 5153

Query: 1237 FMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSS---NVVVEPSGLLELNNFTSQQLDD 1293
             +    VG       PA       P  ++P H SS   N+  EP+       F + +L +
Sbjct: 5154 MVITTTVG------DPA-------PSTSMPVHGSSETTNIKREPT------YFLTPRLRE 5194

Query: 1294 EETAMEQDIDSST 1306
              T+ E    + T
Sbjct: 5195 TSTSQESSFPTDT 5207



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 266/1350 (19%), Positives = 461/1350 (34%), Gaps = 244/1350 (18%)

Query: 82   NMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEV 141
            NM+    SS  ++     + L+    P  + + +   V++   +        +  GS   
Sbjct: 1663 NMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPR 1722

Query: 142  VCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKP 201
            +     +  S+        GS  +   P  +SP +  V    GST + K V+     +  
Sbjct: 1723 LNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDIS 1782

Query: 202  RKRRRTNSSS---------SSPVVLKE----------VPKAVVPVSKTITVPVSGSPKMS 242
            +   RT SSS         S+    KE           P   + V+  I++ +S +P   
Sbjct: 1783 KSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAP--- 1839

Query: 243  NIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAA 302
            N   S+  S   H S      T  S  T  T   ++     + S T   ++   +  + +
Sbjct: 1840 NTTDSLDLSHGVHTSSAGTLATDRSLNTGVTRASRL----ENGSDTSSKSLSMGNSTHTS 1895

Query: 303  VTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTP-- 360
            +T    + V +S   +P      ++++L           T +P    +++T   SS P  
Sbjct: 1896 MTYTEKSEVSSSIHPRPETSAPGAETTL-----------TSTPGNRAISLTLPFSSIPVE 1944

Query: 361  SVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQ 420
             V+ + +  G   ++  M  + +  P  + ++   I       H  S ++   Q Q    
Sbjct: 1945 EVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPY 2004

Query: 421  -QQVAQPSPVSHQ---------QQPQQSPLPPGIKPTIQIKQ--ESGVKIITQQVQ---- 464
               VA  +  +H+           P  S     +  TI  +    S +  +T  +     
Sbjct: 2005 VNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTW 2064

Query: 465  PSKILPKP-------VTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQ--ATYTRPTV 515
            PS  L +        V+    T++  P+   +S  A       T   G Q  A  T  T 
Sbjct: 2065 PSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTD 2124

Query: 516  SPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSK 575
            + S+  ++ TP  A        SI + VP  +A     I S + VSG T++      T+ 
Sbjct: 2125 ASSVTGLSETPVGA--------SISSEVPLPMA-----ITSRSDVSGLTSE-----STAN 2166

Query: 576  PNVIVVQKTTGKGTTIQGLP-GKNVVTTLLNAGGEKTIQTVPTGAKPAILTATR-PITKM 633
            P++        K T    LP  +++V+  +N   +    ++P G+ P   T T  P+   
Sbjct: 2167 PSLGTASSAGTKLTRTISLPTSESLVSFRMNK--DPWTVSIPLGSHPTTNTETSIPVNSA 2224

Query: 634  ----IVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLI---KPKPVTFQATVVSEQTRQ 686
                + T    +  T    A+ IPT + +     T+V      P+  T     +S  T +
Sbjct: 2225 GPPGLSTVASDVIDTPSDGAESIPT-VSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHE 2283

Query: 687  LVT-------ETLQQASRVAEAGNS-SIQEGKEEPQNYTDS---------SSSSTESSQS 729
            L +       + +  A      G S SI  G  E +  T +         ++S TE+S  
Sbjct: 2284 LTSRVTPIPGDWMSSAMSTKPTGASPSITLG--ERRTITSAAPTTSPIVLTASFTETSTV 2341

Query: 730  SQDSQPVV---HVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTT 786
            S D++  V    ++ +R+   +E      +S  +I   ++S +   T T      +  T+
Sbjct: 2342 SLDNETTVKTSDILDARKT--NELPSDSSSSSDLINTSIASSTMDVTKT----ASISPTS 2395

Query: 787  VK-EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            +      S P   + D  Q  VP   T+   ++  SPS++            T   D G+
Sbjct: 2396 ISGMTASSSPSLFSSDRPQ--VPTSTTE--TNTATSPSVS----------SNTYSLDGGS 2441

Query: 846  EVAF------PLLVSHRSQPQQP----SQPQRTLLQHV----AQSQTATQTSVVVKSIPA 891
             V        P  ++H  +        S+P RT    V    A  +  T ++ VV S+PA
Sbjct: 2442 NVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPA 2501

Query: 892  --------------------SSPGAITH-IMQQALSSHTAFTKH-SEELGTEEGEVEEMD 929
                                +SP    H ++   +   TAFT H S  + T      E  
Sbjct: 2502 PGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEAS 2561

Query: 930  TL----------DPQTGLFYRSALTQSQSAKQQK-----------LSQPPLEQTQLQVKT 968
             L           PQT     S      SA  +            L+   L    +   T
Sbjct: 2562 LLTTSESKAIHSSPQTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFST 2621

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQL-------------SIRHQKLTPLQQEQAQPK 1015
            +    +K   T  L        LP  P +             S     L  +  +     
Sbjct: 2622 VSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTV 2681

Query: 1016 PDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQ 1075
            P+   T       D  +   ++ P +++  +     T+    L  +   P   V P+   
Sbjct: 2682 PETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTES--PLHPSSTSPSKIVAPRNTT 2739

Query: 1076 SQMSLPASSEKQTASQVEQPIITQGSSVTKIT-----FEGRQPPTVTKITGGSSVPKLTS 1130
             + S+  +     A      + +Q S  ++ T       G +  +V  +T GS     + 
Sbjct: 2740 YEGSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSG 2799

Query: 1131 PVTSISPIQASEKTAVSDILKMSLME----AQIDTNVEHMIVDPPKKALATSMLTGEAGS 1186
             + S S      KT  S  L M+  E    ++I TN          K +     + E+G 
Sbjct: 2800 GIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGL 2859

Query: 1187 LPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPP--AVP---ATGQFMRIQ 1241
            L             TP       + SSPS   +SLTT    PP   +P    T +F  + 
Sbjct: 2860 L-------------TPV-----SASSSPSKAFASLTTA---PPTWGIPQSTLTFEFSEVP 2898

Query: 1242 NVGQKKAEESPAEIIIQAIPQYAIPCHSSS 1271
            ++  K A        +  IP       SSS
Sbjct: 2899 SLDTKSASLPTPGQSLNTIPDSDASTASSS 2928



 Score = 38.1 bits (87), Expect = 0.056
 Identities = 173/813 (21%), Positives = 280/813 (34%), Gaps = 151/813 (18%)

Query: 206 RTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265
           RT +SS+     KE        + T+TV  +  P               +  P + + T+
Sbjct: 130 RTRTSSTEGNFTKEAS------TYTLTVETTSGPVTEK-----------YTVPTETSTTE 172

Query: 266 PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325
             +  T   T+ + +  TSP  TF  +  SK +         P S+  + T      +T 
Sbjct: 173 GDSTETPWDTRYIPVKITSPMKTFADSTASKEN--------APVSMTPAET-----TVTD 219

Query: 326 SQSSLVSNSSSGSSSS-----TPSPIPNTVAVTA--VVSSTPSVVMSTVAQGVSTSAIKM 378
           S +   +N S G+  S     +P   PN+   T+  ++ ST     S+   G +  +   
Sbjct: 220 SHTPGRTNPSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRIS 279

Query: 379 ASTRLPSPKSLVSAPTQILAQFPKQHQQSP-KQQLYQVQQQTQQQVAQP-----SPVSHQ 432
            S  L S  S++       + F  Q   SP    + + +  T    A P     S     
Sbjct: 280 TSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETS 339

Query: 433 QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS--NSPIMVVSS 490
            +  +S +     P+I  KQ +   +       +  +P    A    S    SP  +  +
Sbjct: 340 AERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGT 399

Query: 491 NGAIMTTKLVTTPTGTQATYTRPTVS----PSIGRMAATPGAATYVKTTSGSIITVVPK- 545
           + + +TT   +T   ++ T T  + S          + TP   +     S    T+VP  
Sbjct: 400 STSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTL 459

Query: 546 SLATLGGKIISSNIVSGT--TTKITTIPMTS---------KPNVIVVQKTTGKGTTIQGL 594
              TL  KI S + VS +  T ++ T   TS           +  +++ TT   +     
Sbjct: 460 GFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSW 519

Query: 595 PGKNVVTTLLNAGGEKTIQTVP---TGAKPAILTATRPITKMI-----------VTQPKG 640
             ++           + ++T P   T   PA  +   PIT  +            +  KG
Sbjct: 520 TSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKG 579

Query: 641 I------------GSTVQPAAK--IIPTKI-------VYGQQGKTQVLIKPKPVTFQATV 679
           I             ST  P      +PT I         G QG T +L +       AT 
Sbjct: 580 IWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTR-------ATA 632

Query: 680 VSEQTRQLVTET----LQQASRVAEAGNSSIQEGKEEPQNYTDSSS--SSTESSQSSQDS 733
            SE +  L   T    +  +  V++    S   G  +P +YT  SS    T S QSS   
Sbjct: 633 SSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKP-SYTMVSSVIPETSSLQSSAFR 691

Query: 734 QPVV---------HVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTI---KALLE 781
           +            H  +S   D + H     + P +    V  +  SATST    KA   
Sbjct: 692 EGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSS 751

Query: 782 LQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKR-HSPESPSIAVVESELVAEYITTER 840
           +  TT   ++ +K +  +  LS M +    T  +R  +  SP               T  
Sbjct: 752 I--TTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSP--------------LTHP 795

Query: 841 TDEGTEVAFPLLVSHRSQPQQPS---QPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAI 897
           +  G E A  +L    S     S    P  TL    ++S +         S+P+ S G  
Sbjct: 796 SPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTL-------SLPSVS-GVK 847

Query: 898 THIMQQALSSHTAFTKHSEELGTEEGEVEEMDT 930
           T       S+H  FT   E   T    V + +T
Sbjct: 848 TTFSSSTPSTH-LFTSGEETEETSNPSVSQPET 879


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 128/554 (23%), Positives = 194/554 (35%), Gaps = 52/554 (9%)

Query: 133  PAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSV 192
            P  T SK     S  + T+ P  T   + S AT  +P P+S       LP  +T  V ++
Sbjct: 4292 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4351

Query: 193  SCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSL 252
            S       P     +   ++     +       P S   T  +      +    +     
Sbjct: 4352 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4411

Query: 253  PPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVI 312
                S    T+      TT TTT       T  S+     IL++    A VT  VPT   
Sbjct: 4412 ATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT--VPTGST 4469

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            A+ +       T   S+  +  +  SS +TPS  P T      + ST +   +T    + 
Sbjct: 4470 ATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIP 4529

Query: 373  TSAIKMASTRLP---SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429
            +S++    TRL    +P + +S  T   +  P+    S               VA PS  
Sbjct: 4530 SSSLGTTWTRLSQTTTPTATMSTATP--SSTPETVHTSTVLTATATTTGATGSVATPSST 4587

Query: 430  SHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPV--------TATLPTS 480
                        PG   T ++   +      T    P   L  PV        T T PT+
Sbjct: 4588 ------------PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTT 4635

Query: 481  SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVS---------PSIGRMAAT---PGA 528
            S S +   S  G   T +++TT T T AT +  T S         PS+   A T    G+
Sbjct: 4636 SGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGS 4695

Query: 529  ATYVKTTSGSI-ITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGK 587
             T   +T G+  IT V  S AT      S    S +    TT+P      V+    T   
Sbjct: 4696 TTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLP------VLTSTATKST 4749

Query: 588  GTTIQGLPGKNVVTT----LLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGS 643
             T+   +P   + TT            T+ T+ T + P   T T  +     T  +   S
Sbjct: 4750 ATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPE-TTHTSTVLTTTATMTRATNS 4808

Query: 644  TVQPAAKIIPTKIV 657
            T  P++ +  T+I+
Sbjct: 4809 TATPSSTLGTTRIL 4822



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 116/530 (21%), Positives = 201/530 (37%), Gaps = 68/530 (12%)

Query: 108  PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164
            P T  TVT    + A   + Q  A  P  + T +   V    TS+ +TP+S+P  + ++ 
Sbjct: 4456 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPSSSPGTATALP 4511

Query: 165  TVKSPRPASPASNVVVLPSGS-----------TVYVKSVSCSDEDEKPRKRRRTNSSSSS 213
             ++S      A++   +PS S           T    ++S +     P     +   +++
Sbjct: 4512 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTAT 4571

Query: 214  PVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS---PVKITFTKPSTQT 270
                        P S   T   +  P  +    +   S  P  +   PV I+ T   T T
Sbjct: 4572 ATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTT 4631

Query: 271  TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL 330
            T TT+   +  ++ P +T    +L+ +    A   +   S    T+  PP + T +    
Sbjct: 4632 TPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTA---- 4687

Query: 331  VSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLV 390
             +  ++  S++ PS  P T  +T V++ST +   +T ++  S+S+ + A+T LP    L 
Sbjct: 4688 -TTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATT-LPV---LT 4742

Query: 391  SAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQI 450
            S  T+  A        S     + V  QT   ++  S +     P+ +            
Sbjct: 4743 STATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETT------------ 4790

Query: 451  KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAI-MTTKLVTTPTGTQAT 509
                           S +L    TAT+  ++NS     S+ G   + T+L TT T T AT
Sbjct: 4791 -------------HTSTVLT--TTATMTRATNSTATPSSTLGTTRILTELTTTATTTAAT 4835

Query: 510  YTRPTVSPSIGRMAATPGAATYVKTTSGSIITV-VPKSLATLGGKIISSNIVSGTTTKIT 568
             +  T+S       +TPG  T++ T   +I TV VP          + +       T + 
Sbjct: 4836 GSTATLS-------STPG-TTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMA 4887

Query: 569  TIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTG 618
            T+P T+  + +    T G   T   LP      ++            PTG
Sbjct: 4888 TMP-TATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTG 4936



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 121/533 (22%), Positives = 197/533 (36%), Gaps = 56/533 (10%)

Query: 147  TSTTSTPTSTP----------------VPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            TS+T+ P+STP                  +GS AT  S    +P   V+  P+ +     
Sbjct: 4237 TSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATS 4296

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            S + S        R  T     +    K    +V P+  +        P+ +    +  +
Sbjct: 4297 SKATSSSS----PRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMS 4352

Query: 251  SLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSST-FVPNILSKSHNYAAVTKLVPT 309
            ++ P  +P + T T  +  TT  TT +    T++PSST     IL++    A  T     
Sbjct: 4353 TIHPSSTP-ETTHTS-TVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGP 4410

Query: 310  SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQ 369
            +   S+T     ++T   ++  + +S+G S++TPS  P T  +    S+T +V + T + 
Sbjct: 4411 TATPSSTPGTTWILTELTTTATTTASTG-STATPSSTPGTTWILTEPSTTATVTVPTGST 4469

Query: 370  GVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429
              ++S    A T  P   +  + PT   ++            L       +     P+  
Sbjct: 4470 ATASSTQATAGT--PHVSTTATTPTVTSSKATPSSSPGTATAL----PALRSTATTPTAT 4523

Query: 430  SHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV---TATLPTSSNSPIM 486
            S    P  S      + +      + +   T    P  +    V   TAT   ++ S   
Sbjct: 4524 SFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVAT 4583

Query: 487  VVSSNGAIMTTKL-VTTPTGTQATYTRPTVSPSIGR-----MAATPGAATYVKTTSGSII 540
              S+ G   TTK+  TT TG  AT   P+ SP         ++ T    T   TTSGS  
Sbjct: 4584 PSSTPGTAHTTKVPTTTTTGFTAT---PSSSPGTALTPPVWISTTTTPTTTTPTTSGS-- 4638

Query: 541  TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV 600
            TV P S+    G   ++ +++ TTT + T  M +  +      T   GT     P     
Sbjct: 4639 TVTPSSIP---GTTHTARVLTTTTTTVATGSMATPSS-----STQTSGTP----PSLTTT 4686

Query: 601  TTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIP 653
             T + A G  T  +   G  P     T   T    T  K   S+    A  +P
Sbjct: 4687 ATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLP 4739



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 144/591 (24%), Positives = 215/591 (36%), Gaps = 81/591 (13%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P   P T + +T    A        S  +P+ T          TST +TPT+T   S   
Sbjct: 2986 PSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTAT---SSKA 3042

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223
             +  SPR A+       LP  ++   KS + S     P       ++ + P       + 
Sbjct: 3043 TSSSSPRTAT------TLPVLTSTATKSTATSFT---PIPSFTLGTTGTLP------EQT 3087

Query: 224  VVPVSKTITVPVSGSPKM---SNIMQSIANSLPPHMSPVKITFTKPSTQ-----TTNTTT 275
              P++   T+  S +P+    S ++ + A +     S    + T  +T      TT  TT
Sbjct: 3088 TTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3147

Query: 276  QKVIIVTTSPSSTFVPN-ILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334
                  T +PSST     IL++    A VT    ++  AS+T+     +    S+  + +
Sbjct: 3148 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3207

Query: 335  SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP---SPKSLVS 391
               SS +TPS  P T      + ST +   +T    + +S++  A TRL    +P + +S
Sbjct: 3208 VI-SSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMS 3266

Query: 392  APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451
              T   +  P+    S          +    VA PS              PG   T ++ 
Sbjct: 3267 TATP--SSTPETVHTSTVLTTTTTTTRATGSVATPSST------------PGTAHTTKVP 3312

Query: 452  QESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQ 507
              +      T    P   L  PV   T T PT+  S +   S  G   T  ++TT T T 
Sbjct: 3313 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTV 3372

Query: 508  ATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTT--- 564
            AT          G M ATP ++T    T  S+ T      AT  G   + +   GTT   
Sbjct: 3373 AT----------GSM-ATPSSSTQTSGTPPSLTTTATTITAT--GSTTNPSSTPGTTPIP 3419

Query: 565  TKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT---LLNAGGEKTIQTVPTGAKP 621
              +TT   T       V  ++  GTT          TT    L      T++T  T A  
Sbjct: 3420 PVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATS 3479

Query: 622  AILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             IL  T       +T+P  + S   PAA    T      Q  T  L  P P
Sbjct: 3480 GILGTTH------ITEPSTVTSHT-PAATTSTT------QHSTPALSSPHP 3517



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 148/646 (22%), Positives = 245/646 (37%), Gaps = 86/646 (13%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
            TS+T+TP+STP  +  I T ++    + A+      +GST    ++  S     P  +  
Sbjct: 2980 TSSTATPSSTPGTTW-ILTEQTTAATTTAT------TGST----AIPSSTPGTAPPPKVL 3028

Query: 207  TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS-PVKITFTK 265
            T+++++      +   +  P + T T+PV      S   +S A S  P  S  +  T T 
Sbjct: 3029 TSTATTPTATSSKATSSSSPRTAT-TLPV----LTSTATKSTATSFTPIPSFTLGTTGTL 3083

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325
            P   TT   T   I  +++P +T    +L+     A  T+   +    S+T     ++T 
Sbjct: 3084 PEQTTTPMATMSTIHPSSTPETTHTSTVLTTK---ATTTRATSSMSTPSSTPGTTWILTE 3140

Query: 326  SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPS 385
              ++  + +++G  ++TPS  P T  +    S+T +V + T +   ++S    A T L  
Sbjct: 3141 LTTAATTTAATG-PTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGT-LKV 3198

Query: 386  PKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK 445
              S  + PT I ++            L       +     P+  S    P  S      +
Sbjct: 3199 LTSTATTPTVISSRATPSSSPGTATAL----PALRSTATTPTATSVTAIPSSSLGTAWTR 3254

Query: 446  PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV---SSNGAIMTTKL-VT 501
             +      + +   T    P  +    V  T  T++ +   V    S+ G   TTK+  T
Sbjct: 3255 LSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTT 3314

Query: 502  TPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVS 561
            T TG  AT   P+ SP          + T   TT GS  TV P S+    G   ++ +++
Sbjct: 3315 TTTGFTAT---PSSSPGTALTPPVWISTTTTPTTRGS--TVTPSSIP---GTTHTATVLT 3366

Query: 562  GTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKP 621
             TTT + T  M +  +      T   GT     P      T + A G  T  +   G  P
Sbjct: 3367 TTTTTVATGSMATPSS-----STQTSGTP----PSLTTTATTITATGSTTNPSSTPGTTP 3417

Query: 622  ----AILTATRP-ITKMIVTQPKGIGSTVQPA---------AKIIP-----------TKI 656
                   TAT P  T   VT    +G+T  P           + +P           T  
Sbjct: 3418 IPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSA 3477

Query: 657  VYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQ---ASRVAEA----GNSSIQEG 709
              G  G T +  +P  VT      +  T Q  T  L     +SR  E+    G ++    
Sbjct: 3478 TSGILGTTHI-TEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHT 3536

Query: 710  KEEPQNYTDSSSSSTESS---QSSQDSQPVVHVIASRRQD---WSE 749
            +   +    ++ S T +S    SS  S P+  V+ +  +    WSE
Sbjct: 3537 RGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSE 3582



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 258/1279 (20%), Positives = 434/1279 (33%), Gaps = 177/1279 (13%)

Query: 108  PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164
            P T  TVT    + A   + Q  A  P  + T +   V    TS+ +TP S+P  + ++ 
Sbjct: 3728 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPFSSPGTATALP 3783

Query: 165  TVKSPRPASPASNVVVLPSGS-----------TVYVKSVSCSDEDEKPRKRRRTNSSSSS 213
             ++S      A++   +PS S           T    ++S +     P     +   +++
Sbjct: 3784 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 3843

Query: 214  PVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP---HMSPVKITFTKPSTQT 270
                +       P S   T   +  P  +    ++  S  P      PV I     ST T
Sbjct: 3844 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWI-----STTT 3898

Query: 271  TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL 330
            T TT+   +  ++ P +T  P +L+ +    A   +   S    T+  PP +IT + +++
Sbjct: 3899 TPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTA-TTI 3957

Query: 331  VSNSSSGSSSSTP--SPIPNTVAVTAVV-SSTPSVVMSTVAQGV--------STSAIKMA 379
             +  S+ + SSTP  +PIP  +  TA   ++T S V  + A G         +T+     
Sbjct: 3958 TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGR 4017

Query: 380  STRLPSPKSLVSAPTQILA-QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQ-- 436
            S    SP ++ +A T   +      H   P          T       +P      P   
Sbjct: 4018 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSR 4077

Query: 437  --QSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAI 494
              +SP  PG   T      +     T    PSK     +  + PTS  +PI         
Sbjct: 4078 TTESPPSPG---TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTS--API--------- 4123

Query: 495  MTTKLVTTPTGTQAT------YTRPTVSPSIG------RMAATPGAATYVKTTSGSIITV 542
              T +VTT    Q        Y+ P   PS G       + A  GA    +   G     
Sbjct: 4124 --TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAV--CEQPLGLECRA 4179

Query: 543  VPKSLATLG--GKIISSNIVSGTTTK----ITTIPMTSKPNVIVV---------QKTTGK 587
              +    LG  G+++  ++  G   +    +    M     + V             T  
Sbjct: 4180 QAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSS 4239

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPT-------GAKPAILTATRPITKMIVTQPKG 640
                   PG   + T L      T  T  T       G  P     T P T    T  K 
Sbjct: 4240 TAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKA 4299

Query: 641  IGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQAT--VVSEQTRQLVT--ETLQQAS 696
              S+    A  +P  +       T   + P P +   T   + EQT   V    T+  +S
Sbjct: 4300 TSSSSPRTATTLPV-LTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSS 4358

Query: 697  RVAEAGNSSIQEGKEEPQNYTDSSSSS-------------TESSQSSQDSQPVVHVIASR 743
                   S++   K      T S+S+              T ++ ++  + P     ++ 
Sbjct: 4359 TPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 4418

Query: 744  RQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLS 803
               W   E+   T+ T      S+ + S+T     +L    TT    +   P   T   S
Sbjct: 4419 GTTWILTELT--TTATTTASTGSTATPSSTPGTTWILTEPSTTATVTV---PTGSTATAS 4473

Query: 804  QMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPS 863
                    TQ    +P   + A   +  V     T  +  GT  A P L S  + P   S
Sbjct: 4474 S-------TQATAGTPHVSTTATTPT--VTSSKATPSSSPGTATALPALRSTATTPTATS 4524

Query: 864  ---QPQRTL-LQHVAQSQTATQTSVVVKSIPASSPGAI-THIMQQALSSHTAFTKHSEEL 918
                P  +L       SQT T T+ +  + P+S+P  + T  +  A ++ T  T      
Sbjct: 4525 FTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATP 4584

Query: 919  GTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQ 978
             +  G      T  P T     +  T + S+       PP+  +     T     T    
Sbjct: 4585 SSTPGTAH--TTKVPTT---TTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGST 4639

Query: 979  TIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQ 1038
                      H    +   +      T      A P    Q +  P        P+L   
Sbjct: 4640 VTPSSIPGTTHTARVLTTTT-----TTVATGSMATPSSSTQTSGTP--------PSLTT- 4685

Query: 1039 PPQTVVQVLAV-KTTQQLPKLQQAPNQPKIYVQPQTPQSQMS-LPASSEKQTASQVEQPI 1096
               T   + A   TT         P  P +     TP +  S   +SS  +TA+ +  P+
Sbjct: 4686 ---TATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTL--PV 4740

Query: 1097 ITQGSSVTKITFEGRQP-PTVTKITGGSSVPKLTSPVTSISPIQAS---EKTAVSDILKM 1152
            +T  S+ TK T     P P+ T  T  +   + T+P++++S I  S   E T  S +L  
Sbjct: 4741 LT--STATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTT 4798

Query: 1153 SLMEAQIDTNV--------EHMIVDPPKKALATSMLTGEAGSL---PSTHMVVAGMANST 1201
            +    +   +            I+        T+  TG   +L   P T  ++   +   
Sbjct: 4799 TATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIA 4858

Query: 1202 PQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIP 1261
                    + ++ ST+G++ T + +   A   T     + +        +PA ++  ++P
Sbjct: 4859 TVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPA-VLPSSLP 4917

Query: 1262 QYAIPCHSSSNV-VVEPSG 1279
             +++   SSS +  + P+G
Sbjct: 4918 TFSVSTVSSSVLTTLRPTG 4936



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 107/426 (25%), Positives = 161/426 (37%), Gaps = 62/426 (14%)

Query: 260  KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKP 319
            K+T T  +T++T +T       +++P +T+   IL++    A VT  VPT   A+ +   
Sbjct: 3698 KLTTTATTTESTGSTATP----SSTPGTTW---ILTEPSTTATVT--VPTGSTATASSTQ 3748

Query: 320  PVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMA 379
                T   S+  +  +  SS +TP   P T      + ST +   +T    + +S++   
Sbjct: 3749 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 3808

Query: 380  STRLP---SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQ 436
             TRL    +P + +S  T   +  P+    S          +    VA PS         
Sbjct: 3809 WTRLSQTTTPTATMSTATP--SSTPETAHTSTVLTTTATTTRATGSVATPSST------- 3859

Query: 437  QSPLPPGIKPTIQIKQESGVKI-ITQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNG 492
                 PG   T ++   +     +T    P      PV   T T PT+S S +   S  G
Sbjct: 3860 -----PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 3914

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
               T  ++TT T T AT          G M ATP ++T    T  S+IT      AT  G
Sbjct: 3915 TTHTPTVLTTTTTTVAT----------GSM-ATPSSSTQTSGTPPSLITTATTITAT--G 3961

Query: 553  KIISSNIVSGTT---TKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT---LLNA 606
               + +   GTT     +TT   T       V  ++  GTT          TT    L+ 
Sbjct: 3962 STTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSP 4021

Query: 607  GGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQV 666
                T++T  T A    L  T       +T+P   G++  PAA    T      Q  T  
Sbjct: 4022 SSPHTVRTAWTSATSGTLGTTH------ITEP-STGTSHTPAATTGTT------QHSTPA 4068

Query: 667  LIKPKP 672
            L  P P
Sbjct: 4069 LSSPHP 4074



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 106/465 (22%), Positives = 179/465 (38%), Gaps = 97/465 (20%)

Query: 108  PQTAFTVT----ANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P T  TVT    + A A++      +L V   T +   V     S+ +TP+S+P  + ++
Sbjct: 3170 PSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVI----SSRATPSSSPGTATAL 3225

Query: 164  ATVKSPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVP 221
              ++S      A++V  +PS S  T + +      +   P     T + SS+P   + V 
Sbjct: 3226 PALRSTATTPTATSVTAIPSSSLGTAWTRL----SQTTTPTATMSTATPSSTP---ETVH 3278

Query: 222  KAVVPVSKTITVPVSGSPKMSNIMQSIANSLP------------PHMSPVKITFTKP--- 266
             + V  + T T   +GS    +     A++              P  SP     T P   
Sbjct: 3279 TSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP-GTALTPPVWI 3337

Query: 267  STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS 326
            ST TT TT    +  ++ P +T    +L+ +    A   +   S    T+  PP  +T +
Sbjct: 3338 STTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS-LTTT 3396

Query: 327  QSSLVSNSSSGSSSSTP--SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP 384
             +++ +  S+ + SSTP  +PIP  +  TA   +TP+   STV     T +  + +T  P
Sbjct: 3397 ATTITATGSTTNPSSTPGTTPIPPVLTTTA---TTPAATSSTV-----TPSSALGTTHTP 3448

Query: 385  SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGI 444
             P    +A T         H +S                                LPP  
Sbjct: 3449 -PVPNTTATT---------HGRS--------------------------------LPPSS 3466

Query: 445  KPTIQI---KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVT 501
              T++       SG+   T   +PS +      AT  T+ +S   + S + +  TT+   
Sbjct: 3467 PHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPP 3526

Query: 502  TPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
            +P  T   +TR T        + T   AT  KT + +++   P S
Sbjct: 3527 SPGTTTPGHTRGT--------SRTTATATPSKTRTSTLLPSSPTS 3563



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 111/498 (22%), Positives = 184/498 (36%), Gaps = 60/498 (12%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPS---GSTVYVKSVSCSDEDEKPRK 203
            TS+T+TP+STP  +  +  + +    + ++     PS   G+T  +   S +     P  
Sbjct: 3680 TSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 3739

Query: 204  RRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQ-SIANSLPPHMS----P 258
               T SS+       +       VS T T P   S K +       A +LP   S    P
Sbjct: 3740 STATASST-------QATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 3792

Query: 259  VKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQK 318
               +FT   + +  TT  + +  TT+P++T      S +   A  + ++ T+  A+TT+ 
Sbjct: 3793 TATSFTAIPSSSLGTTWTR-LSQTTTPTATMSTATPSSTPETAHTSTVLTTT--ATTTRA 3849

Query: 319  PPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKM 378
               V T S       S+ G++ +T  P   T   T   SS+P            T  + +
Sbjct: 3850 TGSVATPS-------STPGTAHTTKVPTTTTTGFTVTPSSSPGT--------ARTPPVWI 3894

Query: 379  ASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQS 438
            ++T  P+       P+ +          +P      V   T   VA  S  +     Q S
Sbjct: 3895 STTTTPTTSGSTVTPSSVPGT-----THTP-----TVLTTTTTTVATGSMATPSSSTQTS 3944

Query: 439  PLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTK 498
              PP +  T      +G          +  +P PV  T  T+  +    V+ + A+ TT 
Sbjct: 3945 GTPPSLITTATTITATGSTTNPSSTPGTTPIP-PVLTTTATTPAATSSTVTPSSALGTTH 4003

Query: 499  LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSN 558
                P  T  T+ R ++SPS      T     +   TSG++ T      +T  G   +  
Sbjct: 4004 TPPVPNTTATTHGR-SLSPSSPHTVRT----AWTSATSGTLGTTHITEPST--GTSHTPA 4056

Query: 559  IVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTG 618
              +GTT   T    +  P+    +     GTT    PG    T+        T    P+ 
Sbjct: 4057 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTT---TPGHTTATS------RTTATATPSK 4107

Query: 619  AKPAILTATRPITKMIVT 636
             + + L  + P +  I T
Sbjct: 4108 TRTSTLLPSSPTSAPITT 4125



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 109/499 (21%), Positives = 183/499 (36%), Gaps = 62/499 (12%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPS---GSTVYVKSVSCSDEDEKPRK 203
            TS+T+ P+STP  +  +  + +    + ++     PS   G+T  +   S +     P  
Sbjct: 2423 TSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 2482

Query: 204  RRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITF 263
               T SS+       +       VS T T P   S K +           P  SP   T 
Sbjct: 2483 STATASST-------QATAGTPHVSTTATTPTVTSSKAT-----------PFSSPGTATA 2524

Query: 264  TKP--STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPV 321
                 ST TT T T    I ++S  +T+           +  T    T   A+ +  P  
Sbjct: 2525 LPALRSTATTPTATSFTAIPSSSLGTTWT--------RLSQTTTPTATMSTATPSSTPET 2576

Query: 322  VITASQSSLVSNSSSGSSS-STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTS---AIK 377
            V T++  +  + ++  + S +TPS  P T   T V+++T +   +T +    T+    + 
Sbjct: 2577 VHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVW 2636

Query: 378  MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQ 437
            +++T  P+ +     P+ I          +P      V   T   VA  S  +     Q 
Sbjct: 2637 ISTTTTPTTRGSTVTPSSIPGT-----THTP-----TVLTTTTTTVATGSMATPSSSTQT 2686

Query: 438  SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497
            S  PP +  T      +G          +  +P PV  T  T+  +    V+ + A+ TT
Sbjct: 2687 SGTPPSLTTTATTITATGSTTNPSSTPGTTPIP-PVLTTTATTPAATSSTVTPSSALGTT 2745

Query: 498  KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557
                 P  T  T+ R ++SPS      T     +   TSG++ T      +T  G   + 
Sbjct: 2746 HTPPVPNTTATTHGR-SLSPSSPHTVRT----AWTSATSGTLGTTHITEPST--GTSHTP 2798

Query: 558  NIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPT 617
               +GTT   T    +  P+    +     GTT    PG    T+        T    P+
Sbjct: 2799 AATTGTTQHSTPALSSPHPSSRTTESPPSPGTT---TPGHTRATS------RTTATATPS 2849

Query: 618  GAKPAILTATRPITKMIVT 636
              + + L  + P +  I T
Sbjct: 2850 KTRTSTLLPSSPTSAPITT 2868



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 100/463 (21%), Positives = 167/463 (36%), Gaps = 94/463 (20%)

Query: 108  PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164
            P T  TVT    + A   + Q  A  P  + T +   V    TS+ +TP S+P  + ++ 
Sbjct: 2471 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPFSSPGTATALP 2526

Query: 165  TVKSPRPASPASNVVVLPSGS-----------TVYVKSVSCSDEDEKPR--------KRR 205
             ++S      A++   +PS S           T    ++S +     P            
Sbjct: 2527 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTT 2586

Query: 206  RTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265
             T + ++  V            +K +T   +G     +     A +LP  +         
Sbjct: 2587 ATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWI--------- 2637

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325
             ST TT TT    +  ++ P +T  P +L+ +    A   +   S    T+  PP  +T 
Sbjct: 2638 -STTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPP-SLTT 2695

Query: 326  SQSSLVSNSSSGSSSSTP--SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRL 383
            + +++ +  S+ + SSTP  +PIP  +  TA   +TP+   STV     T +  + +T  
Sbjct: 2696 TATTITATGSTTNPSSTPGTTPIPPVLTTTA---TTPAATSSTV-----TPSSALGTTHT 2747

Query: 384  PSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPG 443
            P P    +A T         H +S                              SP  P 
Sbjct: 2748 P-PVPNTTATT---------HGRS-----------------------------LSPSSPH 2768

Query: 444  IKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTP 503
               T      SG    T   +PS        AT  T+ +S   + S + +  TT+   +P
Sbjct: 2769 TVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP 2828

Query: 504  TGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              T   +TR T        + T   AT  KT + +++   P S
Sbjct: 2829 GTTTPGHTRAT--------SRTTATATPSKTRTSTLLPSSPTS 2863



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 116/495 (23%), Positives = 173/495 (34%), Gaps = 89/495 (17%)

Query: 147  TSTTSTPTSTP--------VPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDED 198
            TS+T+TP+STP          + +  T  +   A+P S +   P    +   + +     
Sbjct: 1894 TSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATT----- 1948

Query: 199  EKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSP 258
              P       + SSSP     +P     +  T T P + S              P   S 
Sbjct: 1949 --PTVTSSKATPSSSPGTATALP----ALRSTATTPTATS------------VTPIPSSS 1990

Query: 259  VKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQK 318
            +  T+T+ S  TT T T      T +PSST                   P +   ST   
Sbjct: 1991 LGTTWTRLSQTTTPTATMS----TATPSST-------------------PETAHTSTVLT 2027

Query: 319  PPVVITASQSSLVSNSSS-GSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIK 377
                 T +  S+ + SS+ G++ +T  P   T   TA  SS+P   +        T  + 
Sbjct: 2028 ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL--------TPPVW 2079

Query: 378  MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQ 437
            +++T  P+ +     P+ I                  V   T   VA  S  +     Q 
Sbjct: 2080 ISTTTTPTTRGSTVTPSSI----------PGTTHTATVLTTTTTTVATGSMATPSSSTQT 2129

Query: 438  SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497
            S  PP +  T      +G          +  +P PV  T  T+  +    V+ + A+ TT
Sbjct: 2130 SGTPPSLTTTATTITATGSTTNPSSTPGTTPIP-PVLTTTATTPAATSNTVTPSSALGTT 2188

Query: 498  KLVTTPTGTQATYTR--PTVSPSIGRMAATPGAATYVKTTS-GSIITVVPKSLATLGG-- 552
                 P     T+ R  P  SP   R A T   +  + TT      TV   +LA   G  
Sbjct: 2189 HTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTT 2248

Query: 553  ----KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLL-NAG 607
                  +SS   S  TT+    P T+ P       T    TT    P K   +TLL ++ 
Sbjct: 2249 QHSTPALSSPHPSSRTTESPPSPGTTTPG----HTTATSRTTATATPSKTRTSTLLPSSP 2304

Query: 608  GEKTIQTVPT-GAKP 621
                I TV T G +P
Sbjct: 2305 TSAPITTVVTMGCEP 2319



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 95/391 (24%), Positives = 144/391 (36%), Gaps = 54/391 (13%)

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325
            PST  T++T       +++P +T++    + +    A T    T      T  PP V+T 
Sbjct: 1889 PSTPATSSTATP----SSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 1944

Query: 326  SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP- 384
            + ++     +  SS +TPS  P T      + ST +   +T    + +S++    TRL  
Sbjct: 1945 TATT----PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQ 2000

Query: 385  --SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +P + +S  T   +  P+    S               VA PS              P
Sbjct: 2001 TTTPTATMSTATP--SSTPETAHTSTVLTATATTTGATGSVATPSST------------P 2046

Query: 443  GIKPTIQIKQESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTK 498
            G   T ++   +      T    P   L  PV   T T PT+  S +   S  G   T  
Sbjct: 2047 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTAT 2106

Query: 499  LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSN 558
            ++TT T T AT          G M ATP ++T    T  S+ T      AT  G   + +
Sbjct: 2107 VLTTTTTTVAT----------GSM-ATPSSSTQTSGTPPSLTTTATTITAT--GSTTNPS 2153

Query: 559  IVSGTT---TKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT---LLNAGGEKTI 612
               GTT     +TT   T       V  ++  GTT        + TT    L      T+
Sbjct: 2154 STPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTV 2213

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGS 643
            +T  T A   IL  T       +T+P  + S
Sbjct: 2214 RTAWTSATSGILGTTH------ITEPSTVTS 2238



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 94/458 (20%), Positives = 169/458 (36%), Gaps = 83/458 (18%)

Query: 108  PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK 167
            P T  T TA+  + A          P +  +      + TS+ +TP+S+P  + ++  ++
Sbjct: 1913 PTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALR 1972

Query: 168  SPRPASPASNVVVLPSGS-----------TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVV 216
            S      A++V  +PS S           T    ++S +     P     +   +++   
Sbjct: 1973 STATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT 2032

Query: 217  LKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS---PVKITFTKPSTQTTNT 273
                     P S   T   +  P  +    +   S  P  +   PV I     ST TT T
Sbjct: 2033 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWI-----STTTTPT 2087

Query: 274  TTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSN 333
            T    +  ++ P +T    +L+ +    A   +   S    T+  PP  +T + +++ + 
Sbjct: 2088 TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPP-SLTTTATTITAT 2146

Query: 334  SSSGSSSSTP--SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVS 391
             S+ + SSTP  +PIP  +  TA   +TP+   +TV     +SA+    T  P P ++ +
Sbjct: 2147 GSTTNPSSTPGTTPIPPVLTTTA---TTPAATSNTV---TPSSALGTTHTP-PVPNTMAT 2199

Query: 392  APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQ-- 449
                        H +S                                LPP    T++  
Sbjct: 2200 T-----------HGRS--------------------------------LPPSSPHTVRTA 2216

Query: 450  -IKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQA 508
                 SG+   T   +PS +    + AT  T+ +S   + S + +  TT+   +P  T  
Sbjct: 2217 WTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP 2276

Query: 509  TYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
             +T  T        + T   AT  KT + +++   P S
Sbjct: 2277 GHTTAT--------SRTTATATPSKTRTSTLLPSSPTS 2306



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 104/416 (25%), Positives = 148/416 (35%), Gaps = 55/416 (13%)

Query: 270  TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
            TT TTT+      T  S+     IL++    A VT  VPT   A+ +       T   S+
Sbjct: 2444 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVT--VPTGSTATASSTQATAGTPHVST 2501

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP---SP 386
              +  +  SS +TP   P T      + ST +   +T    + +S++    TRL    +P
Sbjct: 2502 TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 2561

Query: 387  KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKP 446
             + +S  T   +  P+    S               VA PS              PG   
Sbjct: 2562 TATMSTATP--SSTPETVHTSTVLTTTATTTGATGSVATPSST------------PGTAH 2607

Query: 447  TIQIKQESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTKLVTT 502
            T ++   +      T    P      PV   T T PT+  S +   S  G   T  ++TT
Sbjct: 2608 TTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTT 2667

Query: 503  PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562
             T T AT          G M ATP ++T    T  S+ T      AT  G   + +   G
Sbjct: 2668 TTTTVAT----------GSM-ATPSSSTQTSGTPPSLTTTATTITAT--GSTTNPSSTPG 2714

Query: 563  TT---TKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT---LLNAGGEKTIQTVP 616
            TT     +TT   T       V  ++  GTT          TT    L+     T++T  
Sbjct: 2715 TTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAW 2774

Query: 617  TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
            T A    L  T       +T+P   G++  PAA    T      Q  T  L  P P
Sbjct: 2775 TSATSGTLGTTH------ITEP-STGTSHTPAATTGTT------QHSTPALSSPHP 2817



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 94/451 (20%), Positives = 153/451 (33%), Gaps = 75/451 (16%)

Query: 322  VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381
            V+     S   ++ + SS++TPS  P T  +    ++T +   ST +    TS ++ A  
Sbjct: 1879 VLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTA-- 1936

Query: 382  RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLP 441
              P PK L +  T                               P+  S +  P  S   
Sbjct: 1937 --PPPKVLTTTAT------------------------------TPTVTSSKATPSSS--- 1961

Query: 442  PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVT 501
            PG    +   + +        V P        T T  + + +P   +S+     T +   
Sbjct: 1962 PGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAH 2021

Query: 502  TPTGTQATYTRPTVSPSIGRMAATPGAA--TYVKTTSGSIITVVPKS------------- 546
            T T   AT T    + S+   ++TPG A  T V TT+ +  T  P S             
Sbjct: 2022 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS 2081

Query: 547  ---LATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT-T 602
                 T  G  ++ + + GTT   T +  T+         T    T   G P     T T
Sbjct: 2082 TTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTAT 2141

Query: 603  LLNAGGEKTIQTVPTGAKP----AILTATRP-ITKMIVTQPKGIGSTVQPAA-------- 649
             + A G  T  +   G  P       TAT P  T   VT    +G+T  P          
Sbjct: 2142 TITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTH 2201

Query: 650  -----KIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNS 704
                    P  +       T  ++    +T  +TV S  T    T T Q ++    + + 
Sbjct: 2202 GRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS-HTLAATTGTTQHSTPALSSPHP 2260

Query: 705  SIQEGKEEPQNYTDSSSSSTESSQSSQDSQP 735
            S +  +  P   T +   +T +S+++  + P
Sbjct: 2261 SSRTTESPPSPGTTTPGHTTATSRTTATATP 2291



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 82/359 (22%), Positives = 134/359 (37%), Gaps = 33/359 (9%)

Query: 297  SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356
            ++ +   T    ++ + S+T     ++T   ++  +  S+GS++ TPS  P T  +    
Sbjct: 2413 NYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTA-TPSSTPGTTWILTEP 2471

Query: 357  SSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQ 416
            S+T +V + T +   ++S    A T  P   +  + PT   ++            L    
Sbjct: 2472 STTATVTVPTGSTATASSTQATAGT--PHVSTTATTPTVTSSKATPFSSPGTATAL---- 2525

Query: 417  QQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV--- 473
               +     P+  S    P  S      + +      + +   T    P  +    V   
Sbjct: 2526 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT 2585

Query: 474  TATLPTSSNSPIMVVSSNGAIMTTK-LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYV 532
            TAT   ++ S     S+ G   TTK L TT TG  AT   P+ SP   R      + T  
Sbjct: 2586 TATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTAT---PSSSPGTARTLPVWISTTTT 2642

Query: 533  KTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQ 592
             TT GS  TV P S+    G   +  +++ TTT + T  M +  +      T   GT   
Sbjct: 2643 PTTRGS--TVTPSSIP---GTTHTPTVLTTTTTTVATGSMATPSS-----STQTSGTP-- 2690

Query: 593  GLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651
              P      T + A G  T  +   G  P       P+     T P    STV P++ +
Sbjct: 2691 --PSLTTTATTITATGSTTNPSSTPGTTP-----IPPVLTTTATTPAATSSTVTPSSAL 2742



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 85/358 (23%), Positives = 129/358 (36%), Gaps = 33/358 (9%)

Query: 299  NYAAVTKLVPTSVIASTTQKPPVV-ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS 357
            NY        TS  A+ +  P    I    ++  + + S  S++TPS  P T  +    S
Sbjct: 3670 NYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPS 3729

Query: 358  STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQ 417
            +T +V + T +   ++S    A T  P   +  + PT   ++            L     
Sbjct: 3730 TTATVTVPTGSTATASSTQATAGT--PHVSTTATTPTVTSSKATPFSSPGTATAL----P 3783

Query: 418  QTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV---T 474
              +     P+  S    P  S      + +      + +   T    P       V   T
Sbjct: 3784 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 3843

Query: 475  ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534
            AT   ++ S     S+ G   TTK+ TT T T  T T P+ SP   R      + T   T
Sbjct: 3844 ATTTRATGSVATPSSTPGTAHTTKVPTTTT-TGFTVT-PSSSPGTARTPPVWISTTTTPT 3901

Query: 535  TSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGL 594
            TSGS  TV P S+    G   +  +++ TTT + T  M           T    T   G 
Sbjct: 3902 TSGS--TVTPSSVP---GTTHTPTVLTTTTTTVATGSMA----------TPSSSTQTSGT 3946

Query: 595  PGKNVVT-TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651
            P   + T T + A G  T  +   G  P       P+     T P    STV P++ +
Sbjct: 3947 PPSLITTATTITATGSTTNPSSTPGTTP-----IPPVLTTTATTPAATSSTVTPSSAL 3999



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 97/439 (22%), Positives = 158/439 (35%), Gaps = 38/439 (8%)

Query: 298  HNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPS-----PIPNTVAV 352
            +++   T    ++   S+T     ++T   ++  + +S+GS+++  S     P P  +  
Sbjct: 1885 YSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 1944

Query: 353  TAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQI-LAQFPKQHQQSPKQQ 411
            TA   +TP+V  S      S       +T LP+ +S  + PT   +   P     +   +
Sbjct: 1945 TA---TTPTVTSSKATPSSSPGT----ATALPALRSTATTPTATSVTPIPSSSLGTTWTR 1997

Query: 412  LYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPK 471
            L     QT    A  S  +    P+ +     +  T      +G         PS     
Sbjct: 1998 L----SQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATG-----SVATPSSTPGT 2048

Query: 472  PVTATLPTSSNSPIMVV-SSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAAT 530
              T  +PT++ +      SS+     T  V   T T  T    TV+PS   +  T   AT
Sbjct: 2049 AHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPS--SIPGTTHTAT 2106

Query: 531  YVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590
             + TT+    TV   S+AT      SS   SGT   +TT   T    +     TT   +T
Sbjct: 2107 VLTTTT---TTVATGSMATPS----SSTQTSGTPPSLTTTATT----ITATGSTTNPSST 2155

Query: 591  IQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK 650
                P   V+TT        +    P+ A     T   P T M  T  + +  +     +
Sbjct: 2156 PGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNT-MATTHGRSLPPSSPHTVR 2214

Query: 651  IIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGK 710
               T    G  G T +  +P  VT      +  T Q  T  L      +    S    G 
Sbjct: 2215 TAWTSATSGILGTTHI-TEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGT 2273

Query: 711  EEPQNYTDSSSSSTESSQS 729
              P + T +S ++  ++ S
Sbjct: 2274 TTPGHTTATSRTTATATPS 2292



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 95/441 (21%), Positives = 157/441 (35%), Gaps = 82/441 (18%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTP------ 157
            P   P+T  T T             S+  P+ T          T+TT+  T+TP      
Sbjct: 4555 PSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGT 4614

Query: 158  --VPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTN------S 209
               P   I+T  +P   +P +      SGSTV   S+  +    +      T       +
Sbjct: 4615 ALTPPVWISTTTTPTTTTPTT------SGSTVTPSSIPGTTHTARVLTTTTTTVATGSMA 4668

Query: 210  SSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQ 269
            + SS       P ++   + TIT   S +   S           P  +P+    T  ST 
Sbjct: 4669 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSST----------PGTTPITPVLT--STA 4716

Query: 270  TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKL--VPTSVIASTTQKPPVVIT-AS 326
            TT   T      ++SP +     +L+ +   +  T    +P+S + +T   P    T  S
Sbjct: 4717 TTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMS 4776

Query: 327  QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS--TPSVVMST--VAQGVSTSAIKMASTR 382
              S +  SS+  ++ T + +  T  +T   +S  TPS  + T  +   ++T+A   A+T 
Sbjct: 4777 TMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATG 4836

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S     T IL                           +PS ++    P  S    
Sbjct: 4837 STATLSSTPGTTWIL--------------------------TEPSTIATVMVPTGS---- 4866

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS-----NSPIMVVSSNGAIMTT 497
                T       G     + V     +P    +T+P+SS      +P ++ SS    + T
Sbjct: 4867 ----TATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSS----LPT 4918

Query: 498  KLVTTPTGTQATYTRPTVSPS 518
              V+T + +  T  RPT  PS
Sbjct: 4919 FSVSTVSSSVLTTLRPTGFPS 4939



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 70/319 (21%), Positives = 122/319 (38%), Gaps = 41/319 (12%)

Query: 105  RLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTP--VPSGS 162
            R++  T  TV   ++A  +     S   P+ T +   +  + T +T+ P+STP   P   
Sbjct: 4653 RVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTI--TATGSTTNPSSTPGTTPITP 4710

Query: 163  IATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPK 222
            + T  +  PA+ +S      S  T     V  S             ++ S+      +P 
Sbjct: 4711 VLTSTATTPAATSSKATSSSSPRTATTLPVLTS------------TATKSTATSFTPIPS 4758

Query: 223  AVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVT 282
            + +    T TVP   +  MS  M +I  S  P  +      T  +T T  T +      T
Sbjct: 4759 STLWT--TWTVPAQTTTPMST-MSTIHTSSTPETTHTSTVLTTTATMTRATNS------T 4809

Query: 283  TSPSSTF-VPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSS 341
             +PSST     IL++    A  T    ++   S+T     ++T   +       +GS+++
Sbjct: 4810 ATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTAT 4869

Query: 342  TPSPI--PNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQ 399
              S +   +T  V   +++ P+   STV    S+S +    T    P SL +     ++ 
Sbjct: 4870 ASSTLGTAHTPKVVTTMATMPTATASTVP---SSSTVGTTRTPAVLPSSLPTFSVSTVSS 4926

Query: 400  ----------FPKQHQQSP 408
                      FP  H  +P
Sbjct: 4927 SVLTTLRPTGFPSSHFSTP 4945



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 172/904 (19%), Positives = 287/904 (31%), Gaps = 178/904 (19%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P   P+TA T T             S+  P+ T          T+TT+  T+T  PS S 
Sbjct: 2013 PSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT--PSSSP 2070

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTN------SSSSSPVVL 217
             T  +P P   ++       GSTV   S+  +           T       ++ SS    
Sbjct: 2071 GTALTP-PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQT 2129

Query: 218  KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQK 277
               P ++   + TIT   S +   S           P  +P+      P   TT  TT  
Sbjct: 2130 SGTPPSLTTTATTITATGSTTNPSST----------PGTTPI------PPVLTTTATTPA 2173

Query: 278  VIIVTTSPSSTF-------VPNIL----------SKSHNYAAVTKLVPTSVIASTTQKPP 320
                T +PSS         VPN +          S  H          + ++ +T    P
Sbjct: 2174 ATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 2233

Query: 321  VVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAS 380
              +T+   +  + ++  S+ +  SP P++    +  S   +    T A   +T+    + 
Sbjct: 2234 STVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK 2293

Query: 381  TRLPS--PKSLVSAPTQILAQFPKQHQQSPKQQL-----------------YQVQQQTQQ 421
            TR  +  P S  SAP   +     + Q +  + L                   ++     
Sbjct: 2294 TRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGA 2353

Query: 422  QVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKI---LPKPVTATLP 478
               QP  +  + Q Q       +   ++   + G+ +   + Q  K        +     
Sbjct: 2354 VCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGL-VCRNREQVGKFKMCFNYEIRVFCC 2412

Query: 479  TSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTV--SPSIGRMAATPGAATYVKTTS 536
               + P    +S+ A+ ++   TT   T+ T T  T   + S    ++TPG    +   S
Sbjct: 2413 NYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPS 2472

Query: 537  GSIITVVP--------KSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVV-----QK 583
             +    VP         + AT G   +S+   + T T     P +S      +       
Sbjct: 2473 TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTA 2532

Query: 584  TTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGS 643
            TT   T+   +P  ++ TT                    +   T P   M    P     
Sbjct: 2533 TTPTATSFTAIPSSSLGTTWTR-----------------LSQTTTPTATMSTATPSSTPE 2575

Query: 644  TVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGN 703
            TV  +  +  T    G  G           T  +T  +  T +++T T            
Sbjct: 2576 TVHTSTVLTTTATTTGATGSV--------ATPSSTPGTAHTTKVLTTT------------ 2615

Query: 704  SSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQ 763
                         T   +++  SS  +  + PV          W    I+  T+PT    
Sbjct: 2616 -------------TTGFTATPSSSPGTARTLPV----------W----ISTTTTPTTRGS 2648

Query: 764  DVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPS 823
             V+  S   T+    +L    TTV                 MA P   TQ    S   PS
Sbjct: 2649 TVTPSSIPGTTHTPTVLTTTTTTVA-------------TGSMATPSSSTQT---SGTPPS 2692

Query: 824  IAVVESELVAEYITTE-RTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQT 882
            +    + + A   TT   +  GT    P+L +  + P              A S T T +
Sbjct: 2693 LTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTP-------------AATSSTVTPS 2739

Query: 883  SVV--VKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYR 940
            S +    + P  +  A TH   ++LS  +  T  +       G +      +P TG  + 
Sbjct: 2740 SALGTTHTPPVPNTTATTH--GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHT 2797

Query: 941  SALT 944
             A T
Sbjct: 2798 PAAT 2801



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 100/466 (21%), Positives = 158/466 (33%), Gaps = 79/466 (16%)

Query: 319  PPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSST------PSVVMSTVAQGVS 372
            P    TA+ SS    +   +  +T +    T   TA+ SST      P V+ ST     +
Sbjct: 2978 PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTA 3037

Query: 373  TSAIKMASTRLPSPKS------LVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQP 426
            TS+    +T   SP++      L S  T+  A                + +QT   +A  
Sbjct: 3038 TSS---KATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094

Query: 427  SPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSK------ILPKPVTATLPTS 480
            S +     P+ +        T+   + +  +  +    PS       IL +  TA   T+
Sbjct: 3095 STIHPSSTPETTH-----TSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTA 3149

Query: 481  SNSPIMVVSSNGAI-------MTTKLVTTPTGTQA-----------------TYTRPTVS 516
            +  P    SS            TT  VT PTG+ A                 T T PTV 
Sbjct: 3150 ATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVI 3209

Query: 517  PSIGRMAATPGAATYV-------KTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITT 569
             S    +++PG AT +        T + + +T +P S  +LG      +  +  T  ++T
Sbjct: 3210 SSRATPSSSPGTATALPALRSTATTPTATSVTAIPSS--SLGTAWTRLSQTTTPTATMST 3267

Query: 570  IPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRP 629
               +S P  +         TT     G   V T  +  G      VPT            
Sbjct: 3268 ATPSSTPETVHTSTVLTTTTTTTRATGS--VATPSSTPGTAHTTKVPTTTTTGFTATPSS 3325

Query: 630  ITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT 689
                 +T P  I +T  P  +           G T         T  ATV++  T  + T
Sbjct: 3326 SPGTALTPPVWISTTTTPTTR-----------GSTVTPSSIPGTTHTATVLTTTTTTVAT 3374

Query: 690  ETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQP 735
             ++   S       SS Q     P   T +++ +   S ++  S P
Sbjct: 3375 GSMATPS-------SSTQTSGTPPSLTTTATTITATGSTTNPSSTP 3413



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 94/394 (23%), Positives = 142/394 (36%), Gaps = 95/394 (24%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P   P+T  T T             S+  P+ T          T+TT+  T+T  PS S 
Sbjct: 2570 PSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTAT--PSSSP 2627

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223
             T ++  P   ++       GSTV   S+                 ++ +P VL      
Sbjct: 2628 GTART-LPVWISTTTTPTTRGSTVTPSSIP---------------GTTHTPTVL------ 2665

Query: 224  VVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTT 283
                + T T   +GS      M + ++S     +P  +T    +T TT T T      TT
Sbjct: 2666 ----TTTTTTVATGS------MATPSSSTQTSGTPPSLT----TTATTITATGS----TT 2707

Query: 284  SPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVIT-----ASQSSLVSNSSSGS 338
            +PSST                          TT  PPV+ T     A+ SS V+ SS+  
Sbjct: 2708 NPSST------------------------PGTTPIPPVLTTTATTPAATSSTVTPSSALG 2743

Query: 339  SSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILA 398
            ++ TP P+PNT A T   S +PS   +      S ++  + +T +  P +  S       
Sbjct: 2744 TTHTP-PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS------- 2795

Query: 399  QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKI 458
                    +P       Q  T   ++ P P S   +  +SP  PG       +  S    
Sbjct: 2796 -------HTPAATTGTTQHST-PALSSPHPSS---RTTESPPSPGTTTPGHTRATSRT-- 2842

Query: 459  ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
             T    PSK     +  + PTS  +PI  V + G
Sbjct: 2843 -TATATPSKTRTSTLLPSSPTS--APITTVVTMG 2873



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 127/564 (22%), Positives = 189/564 (33%), Gaps = 94/564 (16%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
            T+TT    STP P+ S    ++P PAS  + V  L  G T              PR    
Sbjct: 1624 TTTTQALFSTPQPTSSPGLTRAP-PASTTA-VPTLSEGLT-------------SPRYTST 1668

Query: 207  TNSSSS-SPVVLKEVPKAVVPVSKTITVPV-SGSPKMSNIMQSIANSLPPHMSPVKITFT 264
              ++++  P       +  VP   T T+P  S  P  +  + +   S PP ++P  +  +
Sbjct: 1669 LGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATS 1728

Query: 265  KPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVIT 324
            +     T +T  K  + T     +  P + S+     A T    T     TT  P    T
Sbjct: 1729 RARPTGTASTASKEPLTT-----SLAPTLTSELSTSQAETSTPRT----ETTMSPLTNTT 1779

Query: 325  ASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP 384
             SQ +         +       P +      + +  ++     A G    A K    R  
Sbjct: 1780 TSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENI---RAAGGKMCWAPKSIECRAE 1836

Query: 385  S-PKSLVSAPTQIL------AQFPKQHQQSPKQQL---YQVQQ---QTQQQVAQPSPVSH 431
            + P+  +    Q+L          K   Q+ +  +   Y V+                S 
Sbjct: 1837 NYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSS 1896

Query: 432  QQQPQQSPLPPGI--KPTIQIKQESGVKIITQQVQPSKILPKP----VTATLPTSSNSPI 485
               P  +P    I  KPT      +            +  P P     TAT PT ++S  
Sbjct: 1897 TATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKA 1956

Query: 486  MVVSSNGAIMT----TKLVTTPTGTQAT----------------YTRPTVSPSIGRMAAT 525
               SS G            TTPT T  T                 T PT + S    ++T
Sbjct: 1957 TPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSST 2016

Query: 526  PGAA------TYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTS----- 574
            P  A      T   TT+G+  +V   S  +  G   ++ + + TTT  T  P +S     
Sbjct: 2017 PETAHTSTVLTATATTTGATGSVATPS--STPGTAHTTKVPTTTTTGFTATPSSSPGTAL 2074

Query: 575  KPNVIVVQKTT----GKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTG--AKPAILT--- 625
             P V +   TT    G   T   +PG     T+L      T  TV TG  A P+  T   
Sbjct: 2075 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT----TTTTVATGSMATPSSSTQTS 2130

Query: 626  ATRPITKMIVTQPKGIGSTVQPAA 649
             T P      T     GST  P++
Sbjct: 2131 GTPPSLTTTATTITATGSTTNPSS 2154



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 56/221 (25%), Positives = 89/221 (40%), Gaps = 25/221 (11%)

Query: 104  PRLVPQTAFTVTANAVA--NAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSG 161
            P ++  T  TV   ++A  +++ Q + + P    T +      S T+ +STP +TP+P  
Sbjct: 3919 PTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIP-- 3976

Query: 162  SIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVP 221
             + T  +  PA+ +S V    +  T +   V        P     T+  S SP     V 
Sbjct: 3977 PVLTTTATTPAATSSTVTPSSALGTTHTPPV--------PNTTATTHGRSLSPSSPHTVR 4028

Query: 222  KAVVPVSK------TITVPVSG-SPKMSNIMQSIANSLPPHMSP---VKITFTKPSTQTT 271
             A    +        IT P +G S   +    +  +S P   SP    + T + PS  TT
Sbjct: 4029 TAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT 4088

Query: 272  ---NTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPT 309
               +TT       T +PS T    +L  S   A +T +V T
Sbjct: 4089 TPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 4129


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 224/1145 (19%), Positives = 402/1145 (35%), Gaps = 88/1145 (7%)

Query: 145  SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGS---TVYVKSVSCSDEDEKP 201
            S  +TTST  S  + + S+++  +  PA+ ++      +GS   T+ +K+   +      
Sbjct: 4    SEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG 63

Query: 202  RKRRRTNSSSSSPVVLK----EVPKAVVPVSKTITVPVSGSPKMSNIM---QSIANSLPP 254
             +    + + S   ++     E+       S+  TV  +GS   +  M   +S  ++   
Sbjct: 64   SETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGS 123

Query: 255  HMSPVKITFTKP-------STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
              + V IT T+        S  TTN+TT     VT++  S         S    A T   
Sbjct: 124  ETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADS 183

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVM 364
             T+  ++T  +   V TA  S  ++ S++GS ++T S       TV+ T   ++T S   
Sbjct: 184  ETTAASTTGSEMTTVFTAG-SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 242

Query: 365  S--TVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQ 422
            S  T A  + +   K+++    +  S   + T   +    +   +  +        T   
Sbjct: 243  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 302

Query: 423  VAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSN 482
                +  +  +    S +         I  E+  K+ T   + + +          ++  
Sbjct: 303  ETTAASTTGSEPTMASTMGSETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVG 361

Query: 483  SPIMVVSSNGAIMTTKLV-----TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTS 536
            S    VS+ G+  TT  +     +T + T +  T  +   S    A+T G+ AT V TT 
Sbjct: 362  SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG 421

Query: 537  GSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPG 596
                TV      T       S + + +TT   T   +++ + I +  T+   TT     G
Sbjct: 422  SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEG 481

Query: 597  KNVVTTLLNAGGE-KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGST-------VQPA 648
                TT+  AG E KT  T  +    A  T     T   +       ST       V   
Sbjct: 482  SE-TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 540

Query: 649  AKIIPTKIVYGQQGKTQVLIKPKPVTF---------------QATVVSEQTRQLVTETLQ 693
               + T    G +  T      +  T                + T VS    +  T++ +
Sbjct: 541  GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTE 600

Query: 694  QASRVA--EAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHE 751
             +   A   AG+ +      + +N T S++ S  +S S+  S+       S     +  E
Sbjct: 601  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 660

Query: 752  IAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI-- 809
             +  T+ +    + +  S + +       E  +TT      S+    T       V I  
Sbjct: 661  GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITG 720

Query: 810  -QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQR 867
             + T+      E+ + +   SE+    IT +E T   TE +     S  ++  + +    
Sbjct: 721  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS--TEGSETTSAST 778

Query: 868  TLLQHVAQSQTATQTSVV----VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGT 920
            T  +    S T+++T++      ++  AS+ G+ T  +  A S   T FT++SE     T
Sbjct: 779  TGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 838

Query: 921  EEGEVEEMDTLDPQT--GLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQ 978
               E   + T   +T       S  T + S +  + +    E ++    + +  +T    
Sbjct: 839  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 898

Query: 979  TIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQ 1038
            TI  +      +  +    S    + T    E ++             A      T  A 
Sbjct: 899  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 958

Query: 1039 PPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIIT 1098
               +  ++  V TT        A       V     ++  +  A SE  T S       T
Sbjct: 959  TEGS--ELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS-------T 1009

Query: 1099 QGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQ 1158
             GS  T  + EG +  TV+     ++    T   T+I+  + SE T V+     S   A 
Sbjct: 1010 AGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAV 1067

Query: 1159 IDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVG 1218
              T  E            T   TG   +  ST    A +  +T          ++ ST G
Sbjct: 1068 YTTGSETTTTSTEGSETTTVSTTGSETTTAST----ADLETTTVSTS--GSGTTTASTAG 1121

Query: 1219 SSLTT 1223
            S  TT
Sbjct: 1122 SETTT 1126



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 234  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 293

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 294  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 353

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 354  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 413

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 414  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 473

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 474  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 533

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 534  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 593

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 594  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 653

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 654  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 713

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 714  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 771

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 772  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 827

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 828  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 887

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 888  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 924

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 925  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 982

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 983  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1031

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1032 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1091

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1092 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1148

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1149 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1204

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136
              +  A SE  TAS       T GS  T  +  G +  T       +S P      T+ +
Sbjct: 1205 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1257

Query: 1137 PIQASEKTAVS 1147
             I  SE T  S
Sbjct: 1258 FIIGSETTIAS 1268



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 164  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 223

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 224  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 282

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 283  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 342

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 343  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 400

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 401  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 460

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 461  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 510

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 511  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 564

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 565  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 624

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 625  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 682

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 683  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 738

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 739  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 797

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 798  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 852

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 853  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 912

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 913  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 972

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 973  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1032

Query: 927  EMDTL 931
            E  T+
Sbjct: 1033 ETTTV 1037



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 111/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 823  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 880

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 881  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 937

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 938  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 996

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 997  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1056

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1057 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1113

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437
              +  +  S  T +     K    S +         T  +    S    +         +
Sbjct: 1114 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1173

Query: 438  SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497
            +     I         +G +  T   + S+      T T  T+ +      ++     T 
Sbjct: 1174 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1227

Query: 498  KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557
                + T T  T    T +PS              +TT  S  ++ P + +  G +  + 
Sbjct: 1228 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1287

Query: 558  NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616
            +I  SG T   TT+  T+    ++ + T      I   P     TT        ++   P
Sbjct: 1288 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1344

Query: 617  TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676
                    +A       IV    G+G++   A+    T   +G +  T    +P   TFQ
Sbjct: 1345 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1399

Query: 677  AT 678
             T
Sbjct: 1400 ET 1401


>gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo
           sapiens]
          Length = 1064

 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 175/811 (21%), Positives = 284/811 (35%), Gaps = 96/811 (11%)

Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVL---PSGSTVYVKSVSCSDEDEKPRK 203
           +STT T   TP+P+GSI T  SP P        V    P  ST+   +   S      R 
Sbjct: 217 SSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRP 276

Query: 204 RRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITF 263
                 SS    +L   P   VP ++  T   + +  +S ++ ++         P  IT 
Sbjct: 277 TATNTLSSLMSNILSSTP---VPSTEMTTSHTTDTNPLSTLVTTL---------PTTITR 324

Query: 264 TKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVI 323
           + P+++TT   +      T + S+T +      +   +  T L PTS    TT+ P    
Sbjct: 325 STPTSETTYPASPTS---TVTDSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPT 381

Query: 324 TASQSSLVSNSSSGSSSSTPSPIPNTVAV-TAVVSSTP--SVVMSTVAQGVSTSAIKMAS 380
           T   ++    +S  S + + S I +TV+  T  +SS P  S  M T    V T+ +K   
Sbjct: 382 TKLVTTTTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPEL 441

Query: 381 TRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPL 440
             L      + A     +Q P     +   +   +           +       P  S +
Sbjct: 442 ILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVISAI 501

Query: 441 PPGIKPTIQIKQESG------VKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAI 494
            P    T      SG      +  +T  +  S   P     T  T++ +P         +
Sbjct: 502 TPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTPAPNTEVITSHTTTTTP------PSTL 555

Query: 495 MTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG--SIITVVPK---SLAT 549
           +TT        T  + T   +SP+ G +  +    TY  + +G  S  T +P    SL T
Sbjct: 556 VTTLPTAIARSTPTSETTYPISPT-GTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPT 614

Query: 550 LGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLP---GKNVVTTLLNA 606
           +      +  +  TTT+ T+    S  +  +        TTI   P   G  V  T +N 
Sbjct: 615 IETATTPTTNLGNTTTETTSHSTPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNP 674

Query: 607 GGEKT-IQTV-------PTGAKPAILTATRPITK-MIVTQPKGIGSTVQPAAKIIPTK-- 655
               T I T        P+      LTA   +T    V+    + ++V P+A  I  K  
Sbjct: 675 SSLSTDISTTTLKNITQPSVGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKEI 734

Query: 656 -----------------IVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRV 698
                            +   +   T  ++   PVT+  +     +    T+T   +S  
Sbjct: 735 STLVSTTTTTSPTERMTLTSTENTPTSYILTTSPVTYSFSPSMSASSDWTTDTESISS-- 792

Query: 699 AEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSP 758
           A A  S++    E     T +++S T S+     S  V      +    S     +ET+ 
Sbjct: 793 APAITSTLHTTAESTLAPT-TTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTT 851

Query: 759 TIIYQDVSSES----QSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQE 814
                D+S+ES      +T+ I + + L+ T       +     T  LS       +T  
Sbjct: 852 LTPTTDISTESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLS------SLTSS 905

Query: 815 KRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVA 874
              S   PS  V+ S+      TT  T   T V         S P   +    +    V 
Sbjct: 906 ILSSTPVPSTEVITSQ------TTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVT 959

Query: 875 QSQTATQTSVVVK-------SIPASSPGAIT 898
            S T T  S  +        S+PA++   IT
Sbjct: 960 DSTTETTYSTSITGTLSTEISLPATTSSLIT 990



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 167/797 (20%), Positives = 280/797 (35%), Gaps = 125/797 (15%)

Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPT------------- 154
           P   FT    AV + +       P+ +   S   V  S T+TTS PT             
Sbjct: 239 PTPVFTTLKTAVTSTS-------PITSTITSTNTVT-SMTTTTSRPTATNTLSSLMSNIL 290

Query: 155 -STPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSS 213
            STPVPS  + T  +      ++ V  LP   T   +S   S E   P     T + S++
Sbjct: 291 SSTPVPSTEMTTSHTTDTNPLSTLVTTLP---TTITRSTPTS-ETTYPASPTSTVTDSTT 346

Query: 214 PVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNT 273
            +    V      ++ T++ P +  P  S+  Q+    + P    V  T T+ ++Q++  
Sbjct: 347 EITYSTV------LTGTLS-PTTTLPPTSSSQQTTETPMTPTTKLVTTT-TETTSQSSLN 398

Query: 274 TTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVI--------------------- 312
            +   I  T S S+T + ++   S      T +VPT+ +                     
Sbjct: 399 FSSSAIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPELILLEVHDQRIQAKNPRY 458

Query: 313 -----ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS--------- 358
                 S+T   P   T + ++ +S  S  ++ ++ +P+ + +     V+S         
Sbjct: 459 SQTPFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVISAITPKTTVTSMTTTASGPT 518

Query: 359 --------TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSA-PTQILAQFPKQHQQSPK 409
                   T S++ ST A   +T  I   +T    P +LV+  PT I    P      P 
Sbjct: 519 TTNTLSSLTSSILSSTPAP--NTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTYPI 576

Query: 410 QQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTI---------------QIKQES 454
                V     +     S           PL     PTI               +    S
Sbjct: 577 SPTGTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNLGNTTTETTSHS 636

Query: 455 GVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPT 514
                +  +  +  +     ++ P SS + +   + N + ++T + TT   T    T+P+
Sbjct: 637 TPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTT---TLKNITQPS 693

Query: 515 VSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKIT-TIPMT 573
           V  +    AAT   +T+  ++S ++ T V  S  ++  K IS+ + + TTT  T  + +T
Sbjct: 694 VGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTSPTERMTLT 753

Query: 574 SKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKM 633
           S  N       T    T    P        ++A  + T  T    + PAI T+T   T  
Sbjct: 754 STENTPTSYILTTSPVTYSFSPS-------MSASSDWTTDTESISSAPAI-TSTLHTTAE 805

Query: 634 IVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQ 693
               P    S    +A + P        G  Q        TF  T     T  + TE+  
Sbjct: 806 STLAPTTTNS-FTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFM 864

Query: 694 ---------QASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRR 744
                     +S       +S+      P   T ++ SS  SS  S    P   VI S+ 
Sbjct: 865 TPMISTTPITSSMTLRNTMTSMTTAASRPT--TTNTLSSLTSSILSSTPVPSTEVITSQT 922

Query: 745 QDWSEHEIAMETSPTII------YQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQP 798
            + +     + T PT I       +   S S ++T T         T++   L ++   P
Sbjct: 923 TNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTDSTTETTYSTSITGTLSTEISLP 982

Query: 799 TIDLSQMAVPIQMTQEK 815
               S +   I MT  +
Sbjct: 983 ATTSSLITKGISMTSTR 999



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 190/902 (21%), Positives = 331/902 (36%), Gaps = 143/902 (15%)

Query: 119 VANAAIQHNASLPV-----PAETGSKEVVCYSYTS--TTSTPTST------PVPSGSIAT 165
           +A+ A  H  + P+     P +T   E +  S  S  T++TPTS         P   +  
Sbjct: 59  LASPAPGHRENAPMTLTTSPHDTLISETLLSSLVSSNTSTTPTSKFAFKVETTPPTVLVY 118

Query: 166 VKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV 225
           + +     P S ++ +   +++ V +               T +SS +P  + + P   V
Sbjct: 119 LATTECVYPTSFIITISHPTSICVTTTQV------------TFTSSYTPTPVTQKPVTTV 166

Query: 226 PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNT-----------T 274
               T T P++ + K ++ M S  ++     +P+       S   T+T           T
Sbjct: 167 ----TRTYPMTTTEKGTSAMISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRT 222

Query: 275 TQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334
           T++  + T S  +T  P  +  +   A  +    TS I ST     +  T S+ +  +  
Sbjct: 223 TERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTL 282

Query: 335 SSGSSSSTPS-PIPNTVAVTAVVSSTP--SVVMSTVAQGVSTSAIKMASTRLPSPKSLVS 391
           SS  S+   S P+P+T   T+  + T   S +++T+   ++ S     +T   SP S V+
Sbjct: 283 SSLMSNILSSTPVPSTEMTTSHTTDTNPLSTLVTTLPTTITRSTPTSETTYPASPTSTVT 342

Query: 392 ----------------APTQIL--AQFPKQHQQSPKQQLYQVQQQTQQQVAQPS------ 427
                           +PT  L      +Q  ++P     ++   T +  +Q S      
Sbjct: 343 DSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKLVTTTTETTSQSSLNFSSS 402

Query: 428 ---PVSHQQQPQQSPLPP---------GIKPTIQIKQESGVKIITQQVQPSKILPK---- 471
                        S LPP          I PT  +K E    +I  +V   +I  K    
Sbjct: 403 AIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPE----LILLEVHDQRIQAKNPRY 458

Query: 472 ---PVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGA 528
              P T++  TS  +  +  +++  I T  L T  T T    +  T   ++  M  T   
Sbjct: 459 SQTPFTSSTATSPETTTLTCTND--ISTESLTTAMTSTTPVISAITPKTTVTSMTTTASG 516

Query: 529 ATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGT--TTKITTIPMT---SKPNVIVVQK 583
            T   T S S+ + +  S      ++I+S+  + T  +T +TT+P     S P       
Sbjct: 517 PTTTNTLS-SLTSSILSSTPAPNTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTYP 575

Query: 584 TTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGS 643
            +  GT    +      T++       T   + + + P I TAT P T +  T  +    
Sbjct: 576 ISPTGTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNLGNTTTE---- 631

Query: 644 TVQPAAKIIPTKIVYGQQGKTQVLIKPKP------VTFQATVVSEQTRQLVTETLQQASR 697
           T   +     +  +Y     +   I   P      VTF     S  +  + T TL+  ++
Sbjct: 632 TTSHSTPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTTTLKNITQ 691

Query: 698 VAEAGNSSIQEGKEEPQNYTDSSSSS-----TESSQSSQDSQPVVHVIASRRQDWSEHE- 751
            +      +    +    +T SSSS+     T S+ S Q+ +  +  + S     S  E 
Sbjct: 692 PSVGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKE--ISTLVSTTTTTSPTER 749

Query: 752 ---IAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKP----RQPTIDLSQ 804
               + E +PT      S  + S + ++ A      TT  E + S P       T   S 
Sbjct: 750 MTLTSTENTPTSYILTTSPVTYSFSPSMSA--SSDWTTDTESISSAPAITSTLHTTAEST 807

Query: 805 MAVPIQMTQEKRHSPESPSIAVV-----ESELVAEYIT-------TERTDEGTEVAFPLL 852
           +A     +     + E PS AV      +S   +   T       T  TD  TE     +
Sbjct: 808 LAPTTTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFMTPM 867

Query: 853 VSHRSQPQQPSQPQR---TLLQHVAQSQTATQT-SVVVKSIPASSPGAITHIMQQALSSH 908
           +S  + P   S   R   T +   A   T T T S +  SI +S+P   T ++    ++ 
Sbjct: 868 IS--TTPITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSILSSTPVPSTEVITSQTTNT 925

Query: 909 TA 910
           T+
Sbjct: 926 TS 927



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 196/1007 (19%), Positives = 351/1007 (34%), Gaps = 181/1007 (17%)

Query: 241  MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300
            +S+++ S  ++ P      K+  T P+      TT+ V        ++F+  I   +   
Sbjct: 88   LSSLVSSNTSTTPTSKFAFKVETTPPTVLVYLATTECVY------PTSFIITISHPTSIC 141

Query: 301  AAVTKLVPTSVIAST--TQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS 358
               T++  TS    T  TQKP  V T +++  ++ +  G+S+   SP   T   T +V+ 
Sbjct: 142  VTTTQVTFTSSYTPTPVTQKP--VTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVTV 199

Query: 359  TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418
            TPS   S+V+   +T    ++ST                                    +
Sbjct: 200  TPS---SSVSATDTTFHTTISST-----------------------------------TR 221

Query: 419  TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478
            T ++   P+   H      SP P  +  T++    S   I +     + +     T + P
Sbjct: 222  TTERTPLPTGSIH---TTMSPTP--VFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRP 276

Query: 479  TSSNSPIMVVSSNGAIMTTKLVTTPT-GTQATYTRPTVSPSIGRMAAT-PGAATYVKTTS 536
            T++N       +  ++M+  L +TP   T+ T +  T +  +  +  T P   T    TS
Sbjct: 277  TATN-------TLSSLMSNILSSTPVPSTEMTTSHTTDTNPLSTLVTTLPTTITRSTPTS 329

Query: 537  GSIITVVPKSLAT-LGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLP 595
             +     P S  T    +I  S +++GT +  TT+P TS       Q+TT    T    P
Sbjct: 330  ETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSS-----QQTTETPMT----P 380

Query: 596  GKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTK 655
               +VTT      + ++    +     + T+T  I+ +  T       T+  +  I+PT 
Sbjct: 381  TTKLVTTTTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPT-----SGTMVTSTNIVPT- 434

Query: 656  IVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQN 715
                        +KP+ +  +   V +Q  Q       Q    +    S       E   
Sbjct: 435  ----------ADLKPELILLE---VHDQRIQAKNPRYSQTPFTSSTATS------PETTT 475

Query: 716  YTDSSSSSTESSQSSQDS-QPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATS 774
             T ++  STES  ++  S  PV+  I  +    S    A   + T     ++S   S+T 
Sbjct: 476  LTCTNDISTESLTTAMTSTTPVISAITPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTP 535

Query: 775  TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAE 834
                 +    TT      + P    +     A+       +   P SP+  V +S     
Sbjct: 536  APNTEVITSHTTT-----TTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTDSMTEIT 590

Query: 835  YITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSP 894
            Y T+      T    PL        +  + P   L        T T+T+    S P+ + 
Sbjct: 591  YSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNL------GNTTTETT--SHSTPSFTS 642

Query: 895  GAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKL 954
             AI   +  + ++ ++F   S       G +    T++P       S  T   +   + +
Sbjct: 643  SAIYSTVNISTTTISSFPPSS-------GTMVTFTTMNPS------SLSTDISTTTLKNI 689

Query: 955  SQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQP 1014
            +QP +  T           T    T+   +       P  P  SI++++++ L       
Sbjct: 690  TQPSVGSTGFLTAATDLTST---FTVSSSSAMSTSVTPSAP--SIQNKEISTLVSTTTTT 744

Query: 1015 KPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTP 1074
             P            +R   T     P + +   +  T    P +  + +           
Sbjct: 745  SP-----------TERMTLTSTENTPTSYILTTSPVTYSFSPSMSASSD------WTTDT 787

Query: 1075 QSQMSLPA--SSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPV 1132
            +S  S PA  S+   TA     P  T   +    T    +PP+    T G+     TS  
Sbjct: 788  ESISSAPAITSTLHTTAESTLAPTTTNSFT----TSANMEPPSTAVATTGTGQSTFTSST 843

Query: 1133 TSISPIQASEKTAVSDILKMSLMEAQIDT----------NVEHMIVDPPKKALATSMLTG 1182
             +   ++ +  T  +DI   S M   I T          N    +     +   T+ L+ 
Sbjct: 844  ATF--LETTTLTPTTDISTESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSS 901

Query: 1183 EAGSL------PSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
               S+      PST ++ +   N+T           SPST+ ++L T
Sbjct: 902  LTSSILSSTPVPSTEVITSQTTNTT-----------SPSTLVTTLPT 937



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 115/488 (23%), Positives = 208/488 (42%), Gaps = 65/488 (13%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +TA T T N + N   +   S   P+ T S   +  +   +T+T +S P  SG++ T  +
Sbjct: 616  ETATTPTTN-LGNTTTE-TTSHSTPSFTSS--AIYSTVNISTTTISSFPPSSGTMVTFTT 671

Query: 169  PRPASPASNV-------VVLPS-GSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEV 220
              P+S ++++       +  PS GST ++ + +     +       ++SS+ S  V    
Sbjct: 672  MNPSSLSTDISTTTLKNITQPSVGSTGFLTAAT-----DLTSTFTVSSSSAMSTSVTPSA 726

Query: 221  PKAV-VPVSKTITVPVSGSPKMSNIMQSIANSLPPHM---SPVKITFTKPSTQTTNTTTQ 276
            P      +S  ++   + SP     + S  N+   ++   SPV  +F+   + +++ TT 
Sbjct: 727  PSIQNKEISTLVSTTTTTSPTERMTLTSTENTPTSYILTTSPVTYSFSPSMSASSDWTTD 786

Query: 277  KVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQ---KPPVVITAS----QSS 329
                 T S SS   P I S  H  A  T L PT+  + TT    +PP    A+    QS+
Sbjct: 787  -----TESISSA--PAITSTLHTTAEST-LAPTTTNSFTTSANMEPPSTAVATTGTGQST 838

Query: 330  LVSNSSSGSSSSTPSP---IPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP 386
              S++++   ++T +P   I     +T ++S+TP  + S++    + +++  A++R  + 
Sbjct: 839  FTSSTATFLETTTLTPTTDISTESFMTPMISTTP--ITSSMTLRNTMTSMTTAASRPTTT 896

Query: 387  KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKP 446
             +L S  + IL+  P    +    Q       +      P+ ++           P  + 
Sbjct: 897  NTLSSLTSSILSSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTST--------PTSET 948

Query: 447  TIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVS--SNGAIMT-TKLVTTP 503
            T      S V   T +   S      +T TL T  + P    S  + G  MT T+ + T 
Sbjct: 949  TYSTSPTSTVTDSTTETTYST----SITGTLSTEISLPATTSSLITKGISMTSTRNLVTT 1004

Query: 504  TGTQATYTRPTVSPSIGRMAATPGAA-TYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562
            T    +++ PT + +I    +T   A + V TTSG I+T    + ++L   I        
Sbjct: 1005 TNENTSHSTPTFTLTIHSTISTSTTAISSVPTTSGPIVTSTTMTPSSLTADI-------- 1056

Query: 563  TTTKITTI 570
             TT +TTI
Sbjct: 1057 PTTTLTTI 1064



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 114/574 (19%), Positives = 198/574 (34%), Gaps = 74/574 (12%)

Query: 753  AMETSP-TIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQP----TIDLSQMAV 807
            AM +SP T   ++    + + +S++ A      TT+     +  R P    +I  +    
Sbjct: 181  AMISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPT 240

Query: 808  PIQMTQEKRHSPESPSIAVVES-ELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQ 866
            P+  T +   +  SP  + + S   V    TT      T     L+ +  S    PS   
Sbjct: 241  PVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTLSSLMSNILSSTPVPSTEM 300

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T     + +      S +V ++P       T I +   +S T +        T      
Sbjct: 301  TT-----SHTTDTNPLSTLVTTLP-------TTITRSTPTSETTYPASPTSTVT------ 342

Query: 927  EMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQ 986
                 D  T + Y + LT + S      + PP   +Q   +T     TK   T      Q
Sbjct: 343  -----DSTTEITYSTVLTGTLSPTT---TLPPTSSSQQTTETPMTPTTKLVTTTTETTSQ 394

Query: 987  LQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQV 1046
                       S      T +          +  T   MV     +PT   +P   +++V
Sbjct: 395  SSLNFSSSAIYSTVSTSTTAISS--------LPPTSGTMVTSTNIVPTADLKPELILLEV 446

Query: 1047 LAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVE-QPIITQGSSVTK 1105
               +   + P+  Q P        P+T     +   S+E  T +     P+I   S++T 
Sbjct: 447  HDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVI---SAITP 503

Query: 1106 ITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEH 1165
             T       TVT +T  +S P  T+ ++S++          S IL  S      +    H
Sbjct: 504  KT-------TVTSMTTTASGPTTTNTLSSLT----------SSILS-STPAPNTEVITSH 545

Query: 1166 MIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPST-VGSSLTTR 1224
                 P   L T++ T  A S P++          T        + S+  T   S+ TT 
Sbjct: 546  TTTTTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTDSMTEITYSTSMTGTWSTATTL 605

Query: 1225 KIDPPAVP----ATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGL 1280
             +   ++P    AT     + N   +    S       AI  Y+    S++ +   P   
Sbjct: 606  PLTSCSLPTIETATTPTTNLGNTTTETTSHSTPSFTSSAI--YSTVNISTTTISSFPPSS 663

Query: 1281 LELNNFTSQQLDDEETAMEQDIDSST-EDGTEPS 1313
              +  FT+       +++  DI ++T ++ T+PS
Sbjct: 664  GTMVTFTTM----NPSSLSTDISTTTLKNITQPS 693


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 142/692 (20%), Positives = 229/692 (33%), Gaps = 88/692 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3634 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3693 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3732

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3733 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3792

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3793 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3847

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3848 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3900

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3901 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3949

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3950 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P      +     + P
Sbjct: 4064 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP------ITTTTTVTP 4117

Query: 654  TKIVYGQQGKTQVLIKPKPVTFQATVVSEQT-RQLVTETLQQASRVAEAGNSSIQEGKEE 712
            T    G Q  T       P+T   TV    T     T T    +       +    G + 
Sbjct: 4118 TPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4172

Query: 713  PQN--YTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSS--- 767
            P     T +++ +   + +   + P  H   +   + +      E+S     +  SS   
Sbjct: 4173 PTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT 4232

Query: 768  ESQSATSTIKALLELQQTTVKEKLESKPRQPT 799
            ES +  ST+   +E+  T       S P  PT
Sbjct: 4233 ESTTLLSTLPPAIEMTSTAP----PSTPTAPT 4260



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 1909 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1967

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 1968 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2007

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2008 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2067

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2122

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2123 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2175

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2225 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2278

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2338

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2339 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2398

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2399 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2439



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 1978 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2036

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2037 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2076

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2077 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2137 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2191

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2192 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2244

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2293

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2294 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2347

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2407

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2408 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2467

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2468 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2508



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2047 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2105

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2106 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2145

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2260

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2261 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2313

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2314 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2362

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2363 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2416

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2536

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2537 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2577



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2116 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2174

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2175 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2214

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2215 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2275 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2329

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2330 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2383 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2431

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2432 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2485

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2545

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2546 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2605

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2606 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2646



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2185 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2243

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2244 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2283

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2284 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2343

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2344 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2398

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2399 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2500

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2501 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2554

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2674

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2675 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2254 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2313 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2352

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2353 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2412

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2413 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2467

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2468 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2521 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2569

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2570 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2623

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2624 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2683

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2684 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2743

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2744 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2784



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2323 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2382 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2421

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2481

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2482 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2536

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2537 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2589

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2590 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2638

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2639 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2692

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2753 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2812

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2813 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2853



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2392 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2451 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2490

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2491 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2550

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2551 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2605

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2606 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2659 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2707

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2708 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2761

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2762 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2821

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2822 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2881

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2882 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2922



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2461 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2520 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2559

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2674

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2675 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2727

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2728 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2776

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2777 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2830

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2891 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2950

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 2951 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2991



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2530 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2589 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2628

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2629 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2743

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2744 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2796

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2797 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2845

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2846 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2899

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3019

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3020 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3060



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2599 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2658 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2697

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2698 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2757

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2812

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2813 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2865

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2866 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2915 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2968

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3028

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3029 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3088

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3089 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3129



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2668 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2727 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2766

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2767 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2881

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2882 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 2935 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 2983

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 2984 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3037

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3098 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3157

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3158 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2737 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2796 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2835

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2836 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2895

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 2950

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 2951 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3003

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3053 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3106

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3166

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3167 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3226

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3227 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3267



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2806 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2865 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2904

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2905 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3019

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3020 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3072

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3122 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3175

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3236 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3295

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3296 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3336



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2875 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 2934 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 2973

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3088

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3089 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3141

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3142 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3190

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3191 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3244

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3364

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3365 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3405



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 2944 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3003 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3042

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3043 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3102

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3157

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3158 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3259

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3260 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3313

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3314 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3373

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3374 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3433

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3434 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3474



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3013 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3072 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3111

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3171

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3172 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3226

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3227 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3328

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3329 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3382

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3443 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3502

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3503 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3543



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3082 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3141 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3180

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3181 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3240

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3241 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3295

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3296 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3349 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3397

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3398 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3451

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3452 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3511

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3512 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3571

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3572 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3612



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3151 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3210 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3249

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3250 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3309

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3364

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3365 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3418 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3467 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3520

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3581 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3640

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3641 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3681



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3220 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3279 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3318

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3319 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3379 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3433

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3434 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3487 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3535

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3536 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3589

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3590 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3649

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3650 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3709

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3710 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3750



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3289 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3348 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3387

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3388 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3447

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3502

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3503 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3555

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3556 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3604

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3605 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3658

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3659 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3719 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3778

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3779 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3819



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3358 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3417 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3456

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3457 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3517 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3571

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3572 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3625 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3673

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3674 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3727

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3728 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3788 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3847

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3848 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3888



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3427 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3486 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3525

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3526 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3585

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3586 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3640

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3641 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3693

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3694 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3742

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3743 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3796

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3916

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3917 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3957



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3496 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3555 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3594

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3595 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3654

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3655 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3709

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3710 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3762

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3763 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3811

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3812 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3865

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3926 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3985

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 3986 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4026



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 124/581 (21%), Positives = 192/581 (33%), Gaps = 70/581 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3565 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3623

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3624 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 3663

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 3664 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3723

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 3724 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 3778

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 3779 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3831

Query: 428  PVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            P++       +P P G + PT            T     + + P P      T + +PI 
Sbjct: 3832 PITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGTQTPTTTPIT 3880

Query: 487  VVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS 546
              +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +
Sbjct: 3881 TTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3934

Query: 547  LATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGL 594
                G +  ++  ++ TTT             TT P+T+   V      TG  T T   +
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3994

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIP 653
                 VT      G +T  T P      +     P  T+   T P    +TV P      
Sbjct: 3995 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4054

Query: 654  TKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            T+        T   + P P    T   T     T   VT T
Sbjct: 4055 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4095



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 139/653 (21%), Positives = 220/653 (33%), Gaps = 74/653 (11%)

Query: 101  PLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            P  P   P    T T             + P+     +  +   +  S  +T T+TP P+
Sbjct: 1477 PSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536

Query: 161  GSIATVKSP---RPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL 217
                T  SP    P +P ++   LP  +T      + +           T ++ S P + 
Sbjct: 1537 ----TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTIT 1592

Query: 218  KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQK 277
               P      S   T   +  P  +    +     PP  +      T PS   T TTT  
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652

Query: 278  VIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS---TTQKPPVVI------TASQS 328
                TT+PS    P   + S      T   PT+  +S   TT  PP         T + S
Sbjct: 1653 ---PTTTPSP---PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706

Query: 329  SLVSNSSSGSSSSTPSPIPNTVAVTA--VVSSTPSVVMSTVAQGVSTSAIKMASTRLP-- 384
            S ++ +++ SS++TPSP P T+   +     S P+  M+T+    +T++  + +T LP  
Sbjct: 1707 SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP--TTTSSPLTTTPLPPS 1764

Query: 385  ------SPKSLVSAPTQIL----------AQFPKQHQQSPKQQL--------YQVQQQTQ 420
                  SP S  +  T  +          +  P  H+     +L        +      +
Sbjct: 1765 ITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCR 1824

Query: 421  QQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIIT------QQVQPSKILPKPVT 474
              +    P+    Q     +  G+    + ++  GV  +         VQ  + + +P T
Sbjct: 1825 ATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTT 1884

Query: 475  ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534
             T  T+ N      +      T     TPTGTQ   T P  + +      TP       T
Sbjct: 1885 MTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1944

Query: 535  TSGSIITVVPKSLATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQK 583
            T  +  T V  +    G +  ++  ++ TTT             TT P+T+   V     
Sbjct: 1945 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2004

Query: 584  TTGKGT-TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGI 641
             TG  T T   +     VT      G +T  T P      +     P  T+   T P   
Sbjct: 2005 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2064

Query: 642  GSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
             +TV P      T+        T   + P P    T   T     T   VT T
Sbjct: 2065 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2117



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 99/392 (25%), Positives = 141/392 (35%), Gaps = 48/392 (12%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSP----RPASPASNVVVLPSGSTVYVKSVSCSDEDEKPR 202
            T+TT+TP  T  PS  I T  +P     P+ P S     P  +T    + + S     P 
Sbjct: 1426 TTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS 1485

Query: 203  KRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262
                T ++++ P      P    P +  IT P S              +LPP  +P   T
Sbjct: 1486 P--PTTTTTTPPPTTTPSP----PTTTPITPPAS------------TTTLPPTTTPSPPT 1527

Query: 263  FTKPSTQTTNTTTQKVIIVTTSP-SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPV 321
             T  +   T T +       T P S+T +P   + S      T   PT     TT  PP 
Sbjct: 1528 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT-----TTPSPPT 1582

Query: 322  VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMST-VAQGVSTSAIKMAS 380
              T S  ++   +++   ++TPSP P T   T   ++TPS   +T +    ST+ +   +
Sbjct: 1583 TTTPSPPTI--TTTTPPPTTTPSP-PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639

Query: 381  TRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-QQSP 439
            T  P P +  + P       P     SP                 P P +    P   +P
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSP----------PITTTTTPPPTTTPSSPITTTP 1689

Query: 440  LPPGIKPTIQIKQESGVKIITQQVQPSKIL---PKPVTATL--PTSSNSPIMVVSSNGAI 494
             PP    T      +    IT    PS      P P T T   PT++ SP     +    
Sbjct: 1690 SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749

Query: 495  MTTKLVTTPTGTQATYTRPTVSPSIGRMAATP 526
             TT    T T    + T PT SP       TP
Sbjct: 1750 TTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 105/391 (26%), Positives = 144/391 (36%), Gaps = 56/391 (14%)

Query: 226  PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK--------PSTQTTNTTT-- 275
            P+ K IT P   +   S    S   +LPP  +P   T T         PS   T TTT  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTS-TTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP 1449

Query: 276  -----QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL 330
                    I  TT+P  T  P+  + + +    T   PT    +TT  PP   T S  + 
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPT----TTTTTPPPTTTPSPPTT 1505

Query: 331  VSNSSSGSS-----SSTPSPIPNTVAVTAVVSSTPSVVMST-VAQGVSTSAIKMASTRLP 384
               +   S+     ++TPSP P T   T   ++TPS   +T +    ST+ +   +T  P
Sbjct: 1506 TPITPPASTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564

Query: 385  SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSP---VSHQQQPQQSPLP 441
             P +  + P       P     SP      +   T      PSP    +    P  +P P
Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPP----TITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620

Query: 442  PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATL--PTSSNSPIMVVSSNGAIMTTKL 499
            P   P   I   +    +     PS   P P T T   PT++ SP    + +  I TT  
Sbjct: 1621 PTTTP---ITPPTSTTTLPPTTTPS---PPPTTTTTPPPTTTPSPPTTTTPSPPITTT-- 1672

Query: 500  VTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNI 559
             TTP         PT +PS   +  TP   T   TT     T  P S  T      S+  
Sbjct: 1673 -TTPP--------PTTTPS-SPITTTPSPPTTTMTTPSP--TTTPSSPITTTTTPSSTTT 1720

Query: 560  VSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590
             S   T +TT   T+ P+      TT   TT
Sbjct: 1721 PSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT 1751



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 103/429 (24%), Positives = 150/429 (34%), Gaps = 76/429 (17%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPA-SPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
            +T S PT+TP P  +  T   P    SP +     P  +T     ++             
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT------------- 1443

Query: 207  TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKP 266
              ++++ P      P    P+S T T P + +P             PP  +P   T T P
Sbjct: 1444 --TTTTPPPTTTPSP----PISTTTTPPPTTTPS------------PPTTTPSPPT-TTP 1484

Query: 267  STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS 326
            S  TT TTT       + P++T                   P +  ASTT  PP   T +
Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTT-------------------PITPPASTTTLPP---TTT 1522

Query: 327  QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP 386
             S   + +++   ++TPSP P T  +T   S+T     +T +   +T       T  P P
Sbjct: 1523 PSPPTTTTTTPPPTTTPSP-PTTTPITPPTSTTTLPPTTTPSPPPTT-------TTTPPP 1574

Query: 387  KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPL-PPGIK 445
             +  S PT      P     +P          T      P P +    P  +P+ PP   
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT--TTTTPPPTTTPSPPTTTPITPPTST 1632

Query: 446  PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTG 505
             T+           T    P    P P T T P   + PI   ++     T     T T 
Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP---SPPITTTTTPPPTTTPSSPITTTP 1689

Query: 506  TQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTT 565
            +  T T  T SP+      TP +     TT  S  T  P    T       +   S  TT
Sbjct: 1690 SPPTTTMTTPSPT-----TTPSSPITTTTTPSS--TTTPSPPPTTMTTPSPTTTPSPPTT 1742

Query: 566  KITTIPMTS 574
             +TT+P T+
Sbjct: 1743 TMTTLPPTT 1751



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 126/589 (21%), Positives = 198/589 (33%), Gaps = 55/589 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPAS-PASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
            +TT +P +T  PS  I T  +P P + P+S +   PS  T  + + S +     P     
Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT 1713

Query: 207  TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKP 266
            T SS+++P      P   +      T P   +  M+ +  +  +S P   +P+  + T P
Sbjct: 1714 TPSSTTTP----SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS-PLTTTPLPPSITPP 1768

Query: 267  STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV--------PTSVIASTTQK 318
            +    +TTT     V     + ++ +     H     T+L+          ++    T  
Sbjct: 1769 TFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMY 1828

Query: 319  PPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAV-------VSSTPSVVMSTVAQGV 371
            P V I     ++V + S G         P  V   A        V     V   T     
Sbjct: 1829 PDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTT 1888

Query: 372  ST-SAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVS 430
            +T +     +T + +  ++   PT    Q P     +    +      T  Q    +P++
Sbjct: 1889 TTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1948

Query: 431  HQQQPQQSPLPPGIKP--TIQIKQESGVKIITQQVQPSKILPKPVTATL-------PTSS 481
                   +P P G +   T  I   + V               P+T T        PT +
Sbjct: 1949 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2008

Query: 482  NSPIMVVSSNGAIMTTKLVT---TPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGS 538
             +P     +   I TT  VT   TPTGTQ   T P  + +      TP       TT  +
Sbjct: 2009 QTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063

Query: 539  IITVVPKSLATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGK 587
              T V  +    G +  ++  ++ TTT             TT P+T+   V      TG 
Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2123

Query: 588  GT-TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTV 645
             T T   +     VT      G +T  T P      +     P  T+   T P    +TV
Sbjct: 2124 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2183

Query: 646  QPAAKIIPTKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
             P      T+        T   + P P    T   T     T   VT T
Sbjct: 2184 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2232



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 103/483 (21%), Positives = 171/483 (35%), Gaps = 61/483 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++       T+TT T T TP P+G+     +P   +        P+G+     
Sbjct: 3910 PTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3968

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            +   +           T + + +P           P++ T TV  + +P           
Sbjct: 3969 TPITT-----------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---------TG 4008

Query: 251  SLPPHMSPVKITFTKPSTQT---TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            +  P  +P+  T T   T T   T T T   I  TT+ + T  P            T   
Sbjct: 4009 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTV 367
             T     T  + P     + ++ V+ + + + + TP+  P T   T   + TP     T 
Sbjct: 4069 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TG 4123

Query: 368  AQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS 427
             Q  +T+ I   +T  P+P       T    Q P     +    +      T  Q    +
Sbjct: 4124 TQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4176

Query: 428  PVSHQQQPQQSPLPPGIK--PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPI 485
            P++       +P P G +  P          ++ T    P    P+   +T    + S  
Sbjct: 4177 PITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTT 4236

Query: 486  MVVSSNGAIMTTKLV--TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV 543
            ++ +   AI  T     +TPT    T    T+SP      + PG  T   TT+GS     
Sbjct: 4237 LLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR-GTTTGSSSAPT 4295

Query: 544  PKSLATLGGKIISSNIVSGTTTKITTIPM-TSKPNVIVVQKTTGKGTTIQGLPGKNVVTT 602
            P ++ T             TT+  T  P   S P++I   +TTG    ++  P   ++  
Sbjct: 4296 PSTVQTT------------TTSAWTPTPTPLSTPSII---RTTG----LRPYPSSVLICC 4336

Query: 603  LLN 605
            +LN
Sbjct: 4337 VLN 4339



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 123/579 (21%), Positives = 194/579 (33%), Gaps = 57/579 (9%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRP-ASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRR 205
            T+T S PT+T  PS  I T  +P P  +P+S +   PS  T  + + S +     P    
Sbjct: 1654 TTTPSPPTTT-TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712

Query: 206  RTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265
             T SS+++P      P   +      T P   +  M+ +  +  +S P   +P+  + T 
Sbjct: 1713 TTPSSTTTP----SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS-PLTTTPLPPSITP 1767

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV--------PTSVIASTTQ 317
            P+    +TTT     V     + ++ +     H     T+L+          ++    T 
Sbjct: 1768 PTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATM 1827

Query: 318  KPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAV-------VSSTPSVVMSTVAQG 370
             P V I     ++V + S G         P  V   A        V     V   T    
Sbjct: 1828 YPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTT 1887

Query: 371  VST-SAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429
             +T +     +T + +  ++   PT    Q P     +    +      T  Q    +P+
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1947

Query: 430  SHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV 488
            +       +P P G + PT            T     + + P P      T + +PI   
Sbjct: 1948 TTTTTVTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTT 1996

Query: 489  SSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLA 548
            +      T     TPTGTQ   T P  + +      TP       TT  +  T V  +  
Sbjct: 1997 T------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2050

Query: 549  TLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQGLPG 596
              G +  ++  ++ TTT             TT P+T+   V      TG  T T   +  
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110

Query: 597  KNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGSTVQPAAKIIPTK 655
               VT      G +T  T P      +     P  T+   T P    +TV P      T+
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2170

Query: 656  IVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
                    T   + P P    T   T     T   VT T
Sbjct: 2171 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2209



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 107/530 (20%), Positives = 176/530 (33%), Gaps = 54/530 (10%)

Query: 188  YVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQS 247
            Y  +V C +   +P     T + + +P           P++ T TV  + +P  +    +
Sbjct: 1869 YEINVQCCECVTQPTTMTTTTTENPTP-------PTTTPITTTTTVTPTPTPTGTQTPTT 1921

Query: 248  IANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
               +    ++P        +  TT  TT   +  T +P+ T  P            T + 
Sbjct: 1922 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP----ITTTTTVT 1977

Query: 308  PTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS--------ST 359
            PT     T       IT + +   + + +G+ + T +PI  T  VT   +        +T
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2037

Query: 360  PSVVMSTVAQGVSTSAIKMASTR-LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418
            P    +TV    + +  +  +T  + +  ++   PT    Q P     +    +      
Sbjct: 2038 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2097

Query: 419  TQQQVAQPSPVSHQQQPQQSPLPPGIK-PTIQIKQESGVKIITQQVQPSKILPKPVTATL 477
            T  Q    +P++       +P P G + PT            T     + + P P     
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----------TPITTTTTVTPTPTPTGT 2146

Query: 478  PTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG 537
             T + +PI   +      T     TPTGTQ   T P  + +      TP       TT  
Sbjct: 2147 QTPTTTPITTTT------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2200

Query: 538  SIITVVPKSLATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTG 586
            +  T V  +    G +  ++  ++ TTT             TT P+T+   V      TG
Sbjct: 2201 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2260

Query: 587  KGT-TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPI-TKMIVTQPKGIGST 644
              T T   +     VT      G +T  T P      +     P  T+   T P    +T
Sbjct: 2261 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2320

Query: 645  VQPAAKIIPTKIVYGQQGKTQVLIKPKPV---TFQATVVSEQTRQLVTET 691
            V P      T+        T   + P P    T   T     T   VT T
Sbjct: 2321 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2370



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 75/324 (23%), Positives = 123/324 (37%), Gaps = 28/324 (8%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSP---RPASPASNVVVLPSGSTV 187
            P P  T S      S  +TT +P +T   +    T  SP    P +P ++   LP  +T 
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT- 1522

Query: 188  YVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQS 247
                         P     T   +++P      P  + P + T T+P + +P       +
Sbjct: 1523 ----------PSPPTTTTTTPPPTTTPSPPTTTP--ITPPTSTTTLPPTTTPSPP---PT 1567

Query: 248  IANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
               + PP  +P   T T PS  T  TTT       + P++T      + + +    T + 
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627

Query: 308  P----TSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVV 363
            P    T++  +TT  PP   T +     + + S  +++TPSP P T   T   ++TPS  
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPP--TTTPSPPTTTTPSP-PITTTTTPPPTTTPSSP 1684

Query: 364  MSTVAQGVSTSAIKMASTRLP-SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQ 422
            ++T     +T+    + T  P SP +  + P+      P     +           T   
Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744

Query: 423  VAQPSPVSHQQQPQQSPLPPGIKP 446
               P P +       +PLPP I P
Sbjct: 1745 TTLP-PTTTSSPLTTTPLPPSITP 1767



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 48/236 (20%), Positives = 66/236 (27%), Gaps = 10/236 (4%)

Query: 1005 TPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQ 1064
            TP         P    T  P        PT    PP T        TT   P +      
Sbjct: 1538 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP 1597

Query: 1065 PKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKI--TFEGRQPPTVTKITGG 1122
            P     P T  +    P +    T S      IT  +S T +  T     PPT T     
Sbjct: 1598 PTTTPSPPTTTTTTPPPTT----TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653

Query: 1123 SSVPKLTSPVTSISPIQASEK----TAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
            ++ P   +  T   PI  +      T  S  +  +                P      T+
Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT 1713

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPAT 1234
              +      P    +      +TP       +   P+T  S LTT  + P   P T
Sbjct: 1714 TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPT 1769



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 51/221 (23%), Positives = 65/221 (29%), Gaps = 40/221 (18%)

Query: 1014 PKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQT 1073
            P P +  T  P        PT    PP T        TT   P    +P        P T
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT----TTPIT 1509

Query: 1074 PQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVT 1133
            P      PAS+     +    P  T  ++    T     PPT T IT  +S   L  P T
Sbjct: 1510 P------PASTTTLPPTTTPSPPTTTTTTPPPTTTP--SPPTTTPITPPTSTTTL-PPTT 1560

Query: 1134 SISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMV 1193
            + SP   +  T                         PP    +    T  +   P T   
Sbjct: 1561 TPSPPPTTTTT------------------------PPPTTTPSPPTTTTPS---PPTITT 1593

Query: 1194 VAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPAT 1234
                  +TP       +   P+T  S  TT  I PP    T
Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 10/60 (16%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            S  STP+ TP PS S     +P P+ P+S     PS  T   K   C D D  PR+   T
Sbjct: 4375 SCPSTPSPTPTPSKS-----TPTPSKPSST----PSKPTPGTKPPECPDFD-PPRQENET 4424


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 118/505 (23%), Positives = 183/505 (36%), Gaps = 75/505 (14%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
            T+TT  PT TP+ + +  T  +P P S  S     P  +T  V         + P     
Sbjct: 1305 TTTTENPTPTPITTTTTVT-PTPTPTSTQSTTPT-PITTTTTVTPTPTPTGTQTPTTTPI 1362

Query: 207  TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKP 266
            T +++ +P       +       T T  V+ +P  +                   T T  
Sbjct: 1363 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG------------------TQTPT 1404

Query: 267  STQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS 326
            ST  T TTT   +  T +P+ T  P     +      T + PT     T    P  IT +
Sbjct: 1405 STPITTTTT---VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQAPTPTAITTT 1457

Query: 327  QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP 386
             +   + + +G+ + T +PI  T  VT     TP+    T  Q  + +AI   +T  P+ 
Sbjct: 1458 STVTPTPTPTGTQTPTTTPITTTTTVT----PTPT---PTGTQTPTPTAITTTTTVTPT- 1509

Query: 387  KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK- 445
                  PT    Q P     +    +      T  Q   P+P+S       +P P G + 
Sbjct: 1510 ------PTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT 1563

Query: 446  ----PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSN-GAIMTTKLV 500
                P       +     T    P+ +L    T   PT   +P    S+    I TT  V
Sbjct: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTP--TPTSTKSTTVTPITTTTTV 1621

Query: 501  T---TPTGTQA-----TYTRPTVSPSIGRMAATPGAATYVKTTSGSIITV--VPKSLATL 550
            T   TPTGTQ        T  TV+P+      + G  T+  T   + +T    P   +T 
Sbjct: 1622 TATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTP 1681

Query: 551  GGKIISSNIVSGTTTKITTIP------MTSKPNVIVVQKTTGKGTTIQ----------GL 594
                 +S+ ++ +TT ++T+P       T+ P+      TT  G T+           G 
Sbjct: 1682 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT 1741

Query: 595  PGKNVVTTLLNAGGEKTIQTVPTGA 619
            P +   T   +A    T+QT  T A
Sbjct: 1742 PTRGTTTGSSSAPTPSTVQTTTTSA 1766



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 89/403 (22%), Positives = 145/403 (35%), Gaps = 38/403 (9%)

Query: 264  TKPSTQTTNTT---TQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPP 320
            T+P+T TT TT   T   I  TT+ + T  P          +     PT +  +TT  P 
Sbjct: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPT---------STQSTTPTPITTTTTVTPT 1348

Query: 321  VVITASQSSLVSNSSSGSS-SSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMA 379
               T +Q+   +  ++ ++ + TP+P       T  +++T +V  +    G  T      
Sbjct: 1349 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---- 1404

Query: 380  STRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSP 439
            ST + +  ++   PT    Q P     +    +      T  Q   P+ ++       +P
Sbjct: 1405 STPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTP 1464

Query: 440  LPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATL---------PTSSNSPIMVVSS 490
             P G +        +   +           P P   T          PT + +P     +
Sbjct: 1465 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTP-----T 1519

Query: 491  NGAIMTTKLVT---TPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSL 547
            +  I TT  VT   TPTGTQ     P  + +      TP       TT  +  T V  + 
Sbjct: 1520 STPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1579

Query: 548  ATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAG 607
               G +  ++ +++ TTT   T   TS  +  V   TT    T    P      T++   
Sbjct: 1580 TPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPIS 1639

Query: 608  GEKTIQTVPT----GAKPAILTATRPITKMIVTQPKGIGSTVQ 646
               T+   PT       P   T+T PI ++  + P    ST Q
Sbjct: 1640 TTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQ 1682



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 93/433 (21%), Positives = 157/433 (36%), Gaps = 40/433 (9%)

Query: 131  PVPAETGSKEVVCYSYTSTTS-----------TPTSTPVPSGSIATVKSPRPASPASNVV 179
            P P  TG++       T+TT+           TPTSTP+ + +  T       +      
Sbjct: 1370 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTT 1429

Query: 180  VLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSP 239
             + + +TV         +   P     T++ + +P           P++ T TV  + +P
Sbjct: 1430 PITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1489

Query: 240  KMSNIMQSIANSLPPHMSPVKI---TFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSK 296
              +      A +    ++P      T T  ST  T TTT   +  T +P+ T  P     
Sbjct: 1490 TGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTT---VTPTPTPTGTQTPTPTPI 1546

Query: 297  SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356
            S      T + PT     T  + P     + ++ V+ + + + + TP+ +  T   T   
Sbjct: 1547 S----TTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTP 1600

Query: 357  SSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQ 416
            + TP+   ST    ++T+      T  P+P      PT I          +P        
Sbjct: 1601 TPTPTSTKSTTVTPITTTT---TVTATPTPTG-TQTPTMIPISTTTTVTPTPTPTTGSTG 1656

Query: 417  QQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT 476
              T    A  + ++    P +S  P   + T     ES   + T        LP  +  T
Sbjct: 1657 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST--------LPPAIEMT 1708

Query: 477  LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536
                 ++P    +++G    +   +T T    T TR T + S    A TP     V+TT+
Sbjct: 1709 STAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS--SSAPTPST---VQTTT 1763

Query: 537  GSIITVVPKSLAT 549
             S  T  P  L+T
Sbjct: 1764 TSAWTPTPTPLST 1776



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 85/391 (21%), Positives = 138/391 (35%), Gaps = 48/391 (12%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            P P  TG++     + T TTST T TP P+G+     +P   +        P+G+     
Sbjct: 1439 PTPTPTGTQAPTPTAIT-TTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT----- 1492

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
                  +   P     T + + +P           P++ T TV  + +P  +        
Sbjct: 1493 ------QTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546

Query: 251  SLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTS 310
            S    ++P        +  TT  TT   +  T +P+ T  P  +         T + PT 
Sbjct: 1547 STTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVL----ITTTTTMTPTP 1602

Query: 311  VIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQG 370
               ST  K   V   + ++ V+ + + + + TP+ IP +   T   + TP+   +     
Sbjct: 1603 TPTST--KSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTH 1660

Query: 371  VSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVS 430
             ST+ I   +T  P P+S  S P                        QT +  + P    
Sbjct: 1661 TSTAPIAELTTSNPPPES--STP------------------------QTSRSTSSPLT-- 1692

Query: 431  HQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSS 490
             +     S LPP I+ T      S     T       + P P T T P  + +      S
Sbjct: 1693 -ESTTLLSTLPPAIEMT-STAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS 1750

Query: 491  NGAIMTTKLVTTPTGTQATYTRPTVSPSIGR 521
            + A   + + TT T        P  +PSI R
Sbjct: 1751 SSAPTPSTVQTTTTSAWTPTPTPLSTPSIIR 1781



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 63/276 (22%), Positives = 110/276 (39%), Gaps = 29/276 (10%)

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGS----T 186
            P P  TG+ +    +  STT+T T TP P+G+     +P   +        P+G+    T
Sbjct: 1531 PTPTPTGT-QTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589

Query: 187  VYVKSVSCSDEDEKPRKRRRTNSS--------SSSPVVLKEVPKAVVPVSKTITVPVSGS 238
            V + + +       P   + T  +        +++P         ++P+S T TV  + +
Sbjct: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649

Query: 239  PKMSNIMQSIANSLPPHMSPVKITFTKP----STQTTNTTTQKVIIVTTSPSSTFVPNIL 294
            P   +       S  P     ++T + P    ST  T+ +T   +  +T+  ST  P I 
Sbjct: 1650 PTTGSTGPPTHTSTAPI---AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE 1706

Query: 295  SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTA 354
              S      T   PT+     T  PP   T S     +  ++  SSS  +P P+TV  T 
Sbjct: 1707 MTS-TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSS--APTPSTVQTTT 1763

Query: 355  VVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLV 390
              + TP+    +    + T+ ++      P P S++
Sbjct: 1764 TSAWTPTPTPLSTPSIIRTTGLR------PYPSSVL 1793



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 102/467 (21%), Positives = 160/467 (34%), Gaps = 88/467 (18%)

Query: 308  PTSVIASTTQKP-PVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMST 366
            PT++  +TT+ P P  IT + +   + + + + S+TP+PI  T  VT     TP+    T
Sbjct: 1300 PTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTP----TPT---PT 1352

Query: 367  VAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQP 426
              Q  +T+ I   +T  P+P                                T  Q    
Sbjct: 1353 GTQTPTTTPITTTTTVTPTPTP------------------------------TGTQTPTT 1382

Query: 427  SPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIM 486
            +P++       +P P G +              T     + + P P      T + +PI 
Sbjct: 1383 TPITTTTTVTPTPTPTGTQTPTS----------TPITTTTTVTPTPTPTGTQTPTTTPIT 1432

Query: 487  VVSSNGAIMTTKLVTTPTGTQA-TYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545
              +      T     TPTGTQA T T  T + ++       G  T   T   +  TV P 
Sbjct: 1433 TTT------TVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486

Query: 546  SLATLGGKIISSNIVSGTTTKI-----------TTIPMTSKPNVIVVQKTTGKGT-TIQG 593
               T G +  +   ++ TTT             T+ P+T+   V      TG  T T   
Sbjct: 1487 PTPT-GTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTP 1545

Query: 594  LPGKNVVTTLLNAGGEKTIQTVPTGAKPAIL-----TATRPITKMIVTQPKGIGSTVQPA 648
            +     VT      G +T  T P      +      T T+  T +++T    +  T  P 
Sbjct: 1546 ISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPT 1605

Query: 649  AKIIPTKIVYGQQGKTQVLIKPKPVTFQA-TVVSEQTRQLVT------------ETLQQA 695
            +    T  V      T V   P P   Q  T++   T   VT             T    
Sbjct: 1606 STKSTT--VTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTST 1663

Query: 696  SRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIAS 742
            + +AE   S+       PQ    +SS  TES+       P + + ++
Sbjct: 1664 APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST 1710



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 72/324 (22%), Positives = 112/324 (34%), Gaps = 28/324 (8%)

Query: 470  PKPVTATLP-TSSNSPIMVVSSNGA-IMTTKLVT---TPTGTQATYTRPTVSPSIGRMAA 524
            P P+T T   T + +P    S+    I TT  VT   TPTGTQ   T P  + +      
Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1372

Query: 525  TPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKI-----------TTIPMT 573
            TP       TT  +  T V  +    G +  +S  ++ TTT             TT P+T
Sbjct: 1373 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPIT 1432

Query: 574  SKPNVIVVQKTTG-KGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITK 632
            +   V      TG +  T   +   + VT      G +T  T P      +     P   
Sbjct: 1433 TTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1492

Query: 633  MIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQT-RQLVTET 691
               T P  I +T      + PT    G Q  T       P+T   TV    T     T T
Sbjct: 1493 QTPT-PTAITTT----TTVTPTPTPTGTQTPTST-----PITTTTTVTPTPTPTGTQTPT 1542

Query: 692  LQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHE 751
                S       +    G + P     +++++   + +   +Q    V+ +     +   
Sbjct: 1543 PTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTP 1602

Query: 752  IAMETSPTIIYQDVSSESQSATST 775
                T  T +    ++ + +AT T
Sbjct: 1603 TPTSTKSTTVTPITTTTTVTATPT 1626



 Score = 34.7 bits (78), Expect = 0.62
 Identities = 43/203 (21%), Positives = 70/203 (34%), Gaps = 15/203 (7%)

Query: 1033 PTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQV 1092
            PT    P  T +      T    P   Q P    + +   T  +    P S++  T +  
Sbjct: 1558 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--VLITTTTTMTPTPTPTSTKSTTVT-- 1613

Query: 1093 EQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKM 1152
              PI T  +     T  G Q PT+  I+  ++V    +P T  +       TA       
Sbjct: 1614 --PITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPI----- 1666

Query: 1153 SLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCS 1212
                A++ T+        P+ + +TS    E+ +L ST      M ++ P       + +
Sbjct: 1667 ----AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 1722

Query: 1213 SPSTVGSSLTTRKIDPPAVPATG 1235
            S     S   +    PP  P  G
Sbjct: 1723 SGGHTLSPPPSTTTSPPGTPTRG 1745



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 10/60 (16%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            S  STP+ TP PS S     +P P+ P+S     PS  T   K   C D D  PR+   T
Sbjct: 1835 SCPSTPSPTPTPSKS-----TPTPSKPSST----PSKPTPGTKPPECPDFD-PPRQENET 1884


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 124/525 (23%), Positives = 188/525 (35%), Gaps = 43/525 (8%)

Query: 133  PAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSV 192
            P  T SK     S  + T+ P  T   + S AT  +P P+S       LP  +T  V ++
Sbjct: 4762 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4821

Query: 193  SCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSL 252
            S       P     +   ++     +       P S   T  +      +    +     
Sbjct: 4822 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4881

Query: 253  PPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVI 312
                S    T+      TT TTT       T  S+     IL++    A VT  VPT   
Sbjct: 4882 ATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT--VPTGST 4939

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            A+ +       T   S+  +  +  SS +TPS  P T      + ST +   +T    + 
Sbjct: 4940 ATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIP 4999

Query: 373  TSAIKMASTRL---PSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429
            +S++    TRL    +P + +S  T   +  P+    S               VA PS  
Sbjct: 5000 SSSLGTTWTRLSQTTTPTATMSTATP--SSTPETVHTSTVLTATATTTGATGSVATPSST 5057

Query: 430  SHQQQPQQSPLPPGIKPTIQIKQESGVKI-ITQQVQPSKILPKPVTATLPTSSNSPIMVV 488
                        PG   T ++   +      T    P   L  P T   P S+ S I   
Sbjct: 5058 ------------PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTT--PMSTMSTIHTS 5103

Query: 489  SSNGAIMT-TKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSL 547
            S+     T T L TT T T+AT +  T S ++G    T    T + TT+ +  T    S 
Sbjct: 5104 STPETTHTSTVLTTTATMTRATNSTATPSSTLG----TTRILTELTTTATT--TAATGST 5157

Query: 548  ATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTL---- 603
            ATL          +  TT I T P T    ++    T    +T+       VVTT+    
Sbjct: 5158 ATLSS--------TPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMP 5209

Query: 604  -LNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
               A    +  TV T   PA+L ++ P T  + T    + +T++P
Sbjct: 5210 TATASTVPSSSTVGTTRTPAVLPSSLP-TFSVSTVSSSVLTTLRP 5253



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 123/565 (21%), Positives = 208/565 (36%), Gaps = 77/565 (13%)

Query: 147  TSTTSTPTSTP----------------VPSGSIATVKSPRPASPASNVVVLPSGSTVYVK 190
            TS+T+ P+STP                  +GS AT  S    +P   V+  P+ +     
Sbjct: 4707 TSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATS 4766

Query: 191  SVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIAN 250
            S + S        R  T     +    K    +V P+  +        P+ +    +  +
Sbjct: 4767 SKATSSSS----PRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMS 4822

Query: 251  SLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSST-FVPNILSKSHNYAAVTKLVPT 309
            ++ P  +P + T T  +  TT  TT +    T++PSST     IL++    A  T     
Sbjct: 4823 TIHPSSTP-ETTHTS-TVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGP 4880

Query: 310  SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQ 369
            +   S+T     ++T   ++  + +S+G S++TPS  P T  +    S+T +V + T + 
Sbjct: 4881 TATPSSTPGTTWILTELTTTATTTASTG-STATPSSTPGTTWILTEPSTTATVTVPTGST 4939

Query: 370  GVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPV 429
              ++S    A T  P   +  + PT                                S  
Sbjct: 4940 ATASSTQATAGT--PHVSTTATTPT-----------------------------VTSSKA 4968

Query: 430  SHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVS 489
            +    P  +   P ++ T      +    I     PS  L    T T  + + +P   +S
Sbjct: 4969 TPSSSPGTATALPALRSTATTPTATSFTAI-----PSSSL--GTTWTRLSQTTTPTATMS 5021

Query: 490  SNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAA--TYVKTTSGSIITVVPKSL 547
            +     T + V T T   AT T    + S+   ++TPG A  T V TT+ +  T  P S 
Sbjct: 5022 TATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS 5081

Query: 548  ATLGGKIISSNIVSGTTTKITTIPMTSKP------NVIVVQKTTGKGTTIQGLPGKNVVT 601
                G  ++    +  +T ++TI  +S P       V+    T  + T     P   + T
Sbjct: 5082 P---GTALTPPTTTPMST-MSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGT 5137

Query: 602  TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ 661
            T +      T  T       A L++T P T  I+T+P  I + + P           G  
Sbjct: 5138 TRILTELTTTATTTAATGSTATLSST-PGTTWILTEPSTIATVMVPTGSTATASSTLGTA 5196

Query: 662  GKTQVL--IKPKPVTFQATVVSEQT 684
               +V+  +   P    +TV S  T
Sbjct: 5197 HTPKVVTTMATMPTATASTVPSSST 5221



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 144/636 (22%), Positives = 237/636 (37%), Gaps = 121/636 (19%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
            TS+T+TP+STP  +  I T ++    + A+      +GST    ++  S     P  +  
Sbjct: 3560 TSSTATPSSTPGTTW-ILTEQTTAATTTAT------TGST----AIPSSTPGTAPPPKVL 3608

Query: 207  TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS-PVKITFTK 265
            T+++++      +   +  P + T T+PV      S   +S A S  P  S  +  T T 
Sbjct: 3609 TSTATTPTATSSKATSSSSPRTAT-TLPV----LTSTATKSTATSFTPIPSFTLGTTGTL 3663

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325
            P   TT   T   I  +++P +T    +L+     A  T+   +    S+T     ++T 
Sbjct: 3664 PEQTTTPMATMSTIHPSSTPETTHTSTVLTTK---ATTTRATSSMSTPSSTPGTTWILTE 3720

Query: 326  SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPS 385
              ++  + +++G  ++TPS  P T  +    S+T +V + T +   ++S    A T    
Sbjct: 3721 LTTAATTTAATG-PTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTL--- 3776

Query: 386  PKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK 445
             K L S  T                               P+ +S +  P  SP      
Sbjct: 3777 -KVLTSTAT------------------------------TPTVISSRATPSSSPGTATAL 3805

Query: 446  PTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMT-TKLVTTPT 504
            P ++                        TAT PT+++   +  SS G   T     TTPT
Sbjct: 3806 PALR-----------------------STATTPTATSVTAIPSSSLGTAWTRLSQTTTPT 3842

Query: 505  GTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTT 564
             T +T T P+ +P     +      T     +GS+ T  P S     G   ++ + + TT
Sbjct: 3843 ATMSTAT-PSSTPETVHTSTVLTTTTTTTRATGSVAT--PSSTP---GTAHTTKVPTTTT 3896

Query: 565  TKITTIPMTS-----KPNVIVVQKTT----GKGTTIQGLPGKNVVTTLLNAGGEKTIQTV 615
            T  T  P +S      P V +   TT    G   T   +PG     T+L      T  TV
Sbjct: 3897 TGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT----TTTTV 3952

Query: 616  PTG--AKPAILTATRPIT-------KMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQV 666
             TG  A P+  T T   T           T  + +  +     +   T    G  G T +
Sbjct: 3953 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI 4012

Query: 667  LIKPKPVTFQATVVSEQTRQLVTETLQQ---ASRVAEA----GNSSIQEGKEEPQNYTDS 719
              +P  VT      +  T Q  T  L     +SR  E+    G ++    +   +    +
Sbjct: 4013 -TEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATA 4071

Query: 720  SSSSTESS---QSSQDSQPVVHVIASRRQD---WSE 749
            + S T +S    SS  S P+  V+ +  +    WSE
Sbjct: 4072 TPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSE 4107



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 131/569 (23%), Positives = 199/569 (34%), Gaps = 55/569 (9%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P   P T + +T    A        S  +P+ T          TST +TPT+T   S   
Sbjct: 3566 PSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTAT---SSKA 3622

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223
             +  SPR A+       LP  ++   KS + S     P       ++ + P       + 
Sbjct: 3623 TSSSSPRTAT------TLPVLTSTATKSTATSFT---PIPSFTLGTTGTLP------EQT 3667

Query: 224  VVPVSKTITVPVSGSPKM---SNIMQSIANSLPPHMSPVKITFTKPSTQ-----TTNTTT 275
              P++   T+  S +P+    S ++ + A +     S    + T  +T      TT  TT
Sbjct: 3668 TTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3727

Query: 276  QKVIIVTTSPSSTFVPN-ILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334
                  T +PSST     IL++    A VT    ++  AS+T+     +    S+  + +
Sbjct: 3728 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3787

Query: 335  SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP---SPKSLVS 391
               SS +TPS  P T      + ST +   +T    + +S++  A TRL    +P + +S
Sbjct: 3788 VI-SSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMS 3846

Query: 392  APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451
              T   +  P+    S          +    VA PS              PG   T ++ 
Sbjct: 3847 TATP--SSTPETVHTSTVLTTTTTTTRATGSVATPSST------------PGTAHTTKVP 3892

Query: 452  QESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQ 507
              +      T    P   L  PV   T T PT+  S +   S  G   T  ++TT T T 
Sbjct: 3893 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTV 3952

Query: 508  AT--YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTT 565
            AT     P+ S        TP       TT G   ++ P S  T+     S+      TT
Sbjct: 3953 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGR--SLPPSSPHTVRTAWTSATSGILGTT 4010

Query: 566  KITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILT 625
             IT     +         TT   T     P  +  TT        T      G      T
Sbjct: 4011 HITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTAT 4070

Query: 626  ATRPITKMIVTQPKGIGSTVQPAAKIIPT 654
            AT   T+     P     T  P   ++ T
Sbjct: 4071 ATPSKTRTSTLLPS--SPTSAPITTVVTT 4097



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 102/418 (24%), Positives = 156/418 (37%), Gaps = 53/418 (12%)

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQ---KPPVV 322
            PST  T++T       +++P +T+   IL++    A  T    ++ I S+T     PP V
Sbjct: 3555 PSTPATSSTATP----SSTPGTTW---ILTEQTTAATTTATTGSTAIPSSTPGTAPPPKV 3607

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T++ ++  + SS  +SSS+P             ++T  V+ ST  +  +TS   + S  
Sbjct: 3608 LTSTATTPTATSSKATSSSSPR-----------TATTLPVLTSTATKSTATSFTPIPSFT 3656

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
            L +  +L    T  +A     H  S  +  +     T +     +  S    P  +P   
Sbjct: 3657 LGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRA-TSSMSTPSSTPGTT 3715

Query: 443  GIKPTIQIKQESGVKI---ITQQVQPSK--ILPKP---VTATLPTSSNSPIMVVSSNGAI 494
             I   +     +        T    P    IL +P    T T+PT S +     SS  A 
Sbjct: 3716 WILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTA---TASSTRAT 3772

Query: 495  MTTKLVTTPTGTQATY--TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVP-KSLATLG 551
              T  V T T T  T   +R T S S G   A P   +   T + + +T +P  SL T  
Sbjct: 3773 AGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAW 3832

Query: 552  GKIISSNIVSGTTTKITTIPMTSKPNV---------IVVQKTTGKGTTIQGLPG---KNV 599
             ++  S   + T T  T  P ++   V             + TG   T    PG      
Sbjct: 3833 TRL--SQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTK 3890

Query: 600  VTTLLNAGGEKTIQTVP-TGAKPA--ILTATRPITKMIVTQPKGIGSTVQPAAKIIPT 654
            V T    G   T  + P T   P   I T T P T+     P  I  T   A  +  T
Sbjct: 3891 VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTT 3948



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 180/866 (20%), Positives = 307/866 (35%), Gaps = 128/866 (14%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P   P+TA T T         +   S+  P+ T          T+TT+  T T  PS S 
Sbjct: 4352 PSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVT--PSSSP 4409

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223
             T ++P P   ++      SGSTV   SV  +           T  ++ S          
Sbjct: 4410 GTARTP-PVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGS---------M 4459

Query: 224  VVPVSKTITVPVSGSPKMSNIMQSI-ANSLPPHMSP--VKITFTKPSTQTTNTTTQKVII 280
              P S T T   + +P + N   +    SL P  SP  V+  +T  ++ T  TT   +  
Sbjct: 4460 ATPSSSTQTSGTTHTPPVPNTTATTHGRSLSP-SSPHTVRTAWTSATSGTLGTT--HITE 4516

Query: 281  VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340
             +T  S T      +  H+  A++   P+S    TT+ PP   T +     + S + +++
Sbjct: 4517 PSTGTSHTPAATTGTTQHSTPALSSPHPSS---RTTESPPSPGTTTPGHTTATSRT-TAT 4572

Query: 341  STPSPIPNTVAVTAVVSSTP--SVVMSTVAQGVSTSAIKMASTRLPSPK-------SLVS 391
            +TPS    +  + +  +S P  +VV +      + S     S  +P P        S + 
Sbjct: 4573 ATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 4632

Query: 392  APTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451
            A    + + P             +  + + Q     P+    Q  +  L  G+    + +
Sbjct: 4633 AAGGAVCEQP-------------LGLECRAQAQPGVPLGELGQVVECSLDFGL--VCRNR 4677

Query: 452  QESG---------VKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502
            ++ G         +++           P   +  +P+S+     +++    + TT   T 
Sbjct: 4678 EQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTE---LTTTATTTA 4734

Query: 503  PTGTQAT-------------YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLAT 549
             TG+ AT              T P  +P+     AT  ++    TT   + +   KS AT
Sbjct: 4735 STGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTAT 4794

Query: 550  LGGKIISSNI-VSGTTTKITTIPM--------------TSKPNVIVVQKTTGKGT----T 590
                I SS +  +GT  + TT P+              T    V+  + TT + T    T
Sbjct: 4795 SVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTST 4854

Query: 591  IQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKM--IVTQPKGIGSTVQPA 648
                PG   + T L      T  T PT    +    T  +T++    T     GST  P+
Sbjct: 4855 PSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS 4914

Query: 649  AKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQE 708
            +            G T +L +P   T   TV +         T   +S  A AG   +  
Sbjct: 4915 S----------TPGTTWILTEPS-TTATVTVPT-------GSTATASSTQATAGTPHVST 4956

Query: 709  GKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEI---AMETSPTIIYQDV 765
                P     SS ++  SS  +  + P +   A+     S   I   ++ T+ T + Q  
Sbjct: 4957 TATTPT--VTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTT 5014

Query: 766  SSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIA 825
            +  +  +T+T  +  E   T+    + +     T     +A P         +P +    
Sbjct: 5015 TPTATMSTATPSSTPETVHTST---VLTATATTTGATGSVATP-------SSTPGTAHTT 5064

Query: 826  VVESELVAEYITTERTDEGTEVAFPLL--VSHRSQPQQPSQPQRTLLQHVAQSQTATQTS 883
             V +     +  T  +  GT +  P    +S  S     S P+ T    V  + TAT T 
Sbjct: 5065 KVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVL-TTTATMTR 5123

Query: 884  VVVKSIPASSPGAITHIMQQALSSHT 909
                +   SS    T I+ +  ++ T
Sbjct: 5124 ATNSTATPSSTLGTTRILTELTTTAT 5149



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 90/391 (23%), Positives = 155/391 (39%), Gaps = 48/391 (12%)

Query: 108  PQTAFTVT----ANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P T  TVT    + A A++      +L V   T +   V     S+ +TP+S+P  + ++
Sbjct: 3750 PSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVI----SSRATPSSSPGTATAL 3805

Query: 164  ATVKSPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVP 221
              ++S      A++V  +PS S  T + +      +   P     T + SS+P   + V 
Sbjct: 3806 PALRSTATTPTATSVTAIPSSSLGTAWTRL----SQTTTPTATMSTATPSSTP---ETVH 3858

Query: 222  KAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIV 281
             + V  + T T   +GS    +     A     H + V  T T   T T +++    +  
Sbjct: 3859 TSTVLTTTTTTTRATGSVATPSSTPGTA-----HTTKVPTTTTTGFTATPSSSPGTALTP 3913

Query: 282  TTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSS 341
                S+T  P     +   +++     T+ + +TT     V T S ++  S++ +  ++ 
Sbjct: 3914 PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT--TVATGSMATPSSSTQTSGTTH 3971

Query: 342  TPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFP 401
            TP P+PNT A T   S  PS   +      S ++  + +T +  P S V++ T       
Sbjct: 3972 TP-PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP-STVTSHTPAATTST 4029

Query: 402  KQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQ 461
             QH              +   ++ P P S   +  +SP  PG   T       G    T 
Sbjct: 4030 TQH--------------STPALSSPHPSS---RTTESPPSPG---TTTPGHTRGTSRTTA 4069

Query: 462  QVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
               PSK     +  + PTS  +PI  V + G
Sbjct: 4070 TATPSKTRTSTLLPSSPTS--APITTVVTTG 4098



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 99/429 (23%), Positives = 161/429 (37%), Gaps = 63/429 (14%)

Query: 260  KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKP 319
            K+T T  +T++T +T       +++P +T+   IL++    A VT  VPT   A+ +   
Sbjct: 4223 KLTTTATTTESTGSTATP----SSTPGTTW---ILTEPSTTATVT--VPTGSTATASSTQ 4273

Query: 320  PVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMA 379
                T   S+  +  +  SS +TP   P T      + ST +   +T    + +S++   
Sbjct: 4274 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 4333

Query: 380  STRL---PSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQ 436
             TRL    +P + +S  T   +  P+    S          +    VA PS         
Sbjct: 4334 WTRLSQTTTPTATMSTATP--SSTPETAHTSTVLTTTATTTRATGSVATPSST------- 4384

Query: 437  QSPLPPGIKPTIQIKQESGVKI-ITQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNG 492
                 PG   T ++   +     +T    P      PV   T T PT+S S +   S  G
Sbjct: 4385 -----PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 4439

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT-VVPKSLATLG 551
               T  ++TT T T AT          G M ATP ++T    TSG+  T  VP + AT  
Sbjct: 4440 TTHTPTVLTTTTTTVAT----------GSM-ATPSSST---QTSGTTHTPPVPNTTATTH 4485

Query: 552  GKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKT 611
            G+ +S +      T  T+    +     + + +TG   T     G    +T   +    +
Sbjct: 4486 GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 4545

Query: 612  IQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPK 671
             +T  +   P              T P    +T +  A   P+K       +T  L+   
Sbjct: 4546 SRTTESPPSPG------------TTTPGHTTATSRTTATATPSKT------RTSTLLPSS 4587

Query: 672  PVTFQATVV 680
            P +   T V
Sbjct: 4588 PTSAPITTV 4596



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 84/387 (21%), Positives = 151/387 (39%), Gaps = 40/387 (10%)

Query: 108  PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK 167
            P T  T TA+  + A          P +  +      + TS+ +TP+S+P  + ++  ++
Sbjct: 2603 PTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALR 2662

Query: 168  SPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV 225
            S      A++V  +PS S  T + +      +   P     T + SS+P   +    + V
Sbjct: 2663 STATTPTATSVTPIPSSSLGTTWTR----LSQTTTPTATMSTATPSSTP---ETAHTSTV 2715

Query: 226  PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSP 285
              +   T   +GS    +     A     H + V  T T   T T +++    +      
Sbjct: 2716 LTATATTTGATGSVATPSSTPGTA-----HTTKVPTTTTTGFTATPSSSPGTALTPPVWI 2770

Query: 286  SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSP 345
            S+T  P     +   +++     T+ + +TT     V T S ++  S++ +  ++ TP P
Sbjct: 2771 STTTTPTTRGSTVTPSSIPGTTHTATVLTTT--TTTVATGSMATPSSSTQTSGTTHTP-P 2827

Query: 346  IPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQ 405
            +PNT+A T   S  PS   +      S ++  + +T +  P S V++ T        QH 
Sbjct: 2828 VPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP-STVTSHTLAATTGTTQH- 2885

Query: 406  QSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQP 465
                         +   ++ P P S   +  +SP  PG   T      +     T    P
Sbjct: 2886 -------------STPALSSPHPSS---RTTESPPSPG---TTTPGHTTATSRTTATATP 2926

Query: 466  SKILPKPVTATLPTSSNSPIMVVSSNG 492
            SK     +  + PTS  +PI  V + G
Sbjct: 2927 SKTRTSTLLPSSPTS--APITTVVTMG 2951



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 182/854 (21%), Positives = 294/854 (34%), Gaps = 138/854 (16%)

Query: 108  PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164
            P T  TVT    + A   + Q  A  P  + T +   V    TS+ +TP S+P  + ++ 
Sbjct: 4253 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPFSSPGTATALP 4308

Query: 165  TVKSPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPK 222
             ++S      A++   +PS S  T + +      +   P     T + SS+P   +    
Sbjct: 4309 ALRSTATTPTATSFTAIPSSSLGTTWTR----LSQTTTPTATMSTATPSSTP---ETAHT 4361

Query: 223  AVVPVSKTITVPVSGSPKMSNIMQSIANSLP-PHMSPVKITFTKPSTQTTNTTTQKVIIV 281
            + V  +   T   +GS    +     A++   P  +    T T  S+  T  T    I  
Sbjct: 4362 STVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIST 4421

Query: 282  TTSPS---STFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGS 338
            TT+P+   ST  P+ +         T   PT +  +TT     V T S ++  S++ +  
Sbjct: 4422 TTTPTTSGSTVTPSSVPG-------TTHTPTVLTTTTT----TVATGSMATPSSSTQTSG 4470

Query: 339  SSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILA 398
            ++ TP P+PNT A T   S +PS   +      S ++  + +T +  P +  S       
Sbjct: 4471 TTHTP-PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS------- 4522

Query: 399  QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKI 458
                    +P       Q  T   ++ P P S   +  +SP  PG   T      +    
Sbjct: 4523 -------HTPAATTGTTQHST-PALSSPHPSS---RTTESPPSPG---TTTPGHTTATSR 4568

Query: 459  ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQAT------YTR 512
             T    PSK     +  + PTS  +PI           T +VTT    Q        Y+ 
Sbjct: 4569 TTATATPSKTRTSTLLPSSPTS--API-----------TTVVTTGCEPQCAWSEWLDYSY 4615

Query: 513  PTVSPSIG------RMAATPGAATYVKTTSGSIITVVPKSLATLG--GKIISSNIVSGTT 564
            P   PS G       + A  GA    +   G       +    LG  G+++  ++  G  
Sbjct: 4616 PMPGPSGGDFDTYSNIRAAGGAV--CEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLV 4673

Query: 565  TK----ITTIPMTSKPNVIVV---------QKTTGKGTTIQGLPGKNVVTTLLNAGGEKT 611
             +    +    M     + V             T         PG   + T L      T
Sbjct: 4674 CRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTT 4733

Query: 612  IQTVPT-------GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKT 664
              T  T       G  P     T P T    T  K   S+    A  +P  +       T
Sbjct: 4734 ASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPV-LTSTATKST 4792

Query: 665  QVLIKPKPVTFQAT--VVSEQTRQLVT--ETLQQASRVAEAGNSSIQEGKEEPQNYTDSS 720
               + P P +   T   + EQT   V    T+  +S       S++   K      T S+
Sbjct: 4793 ATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSST 4852

Query: 721  SSS-------------TESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSS 767
            S+              T ++ ++  + P     ++    W   E+   T+ T      S+
Sbjct: 4853 STPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELT--TTATTTASTGST 4910

Query: 768  ESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVV 827
             + S+T     +L    TT    +   P   T   S        TQ    +P   + A  
Sbjct: 4911 ATPSSTPGTTWILTEPSTTATVTV---PTGSTATASS-------TQATAGTPHVSTTATT 4960

Query: 828  ESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPS---QPQRTL-LQHVAQSQTATQTS 883
             +  V     T  +  GT  A P L S  + P   S    P  +L       SQT T T+
Sbjct: 4961 PT--VTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 5018

Query: 884  VVVKSIPASSPGAI 897
             +  + P+S+P  +
Sbjct: 5019 TMSTATPSSTPETV 5032



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 98/427 (22%), Positives = 150/427 (35%), Gaps = 87/427 (20%)

Query: 322  VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381
            V+     S   ++ + SS++TPS  P T  +    ++T +   ST +    TS ++ A  
Sbjct: 2569 VLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTA-- 2626

Query: 382  RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLP 441
              P PK L +  T                               P+  S +  P  SP  
Sbjct: 2627 --PPPKVLTTTAT------------------------------TPTVTSSKATPSSSPGT 2654

Query: 442  PGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMT-TKLV 500
                P ++                        TAT PT+++   +  SS G   T     
Sbjct: 2655 ATALPALR-----------------------STATTPTATSVTPIPSSSLGTTWTRLSQT 2691

Query: 501  TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
            TTPT T +T T P+ +P     A T    T   TT+G+  +V   S  +  G   ++ + 
Sbjct: 2692 TTPTATMSTAT-PSSTP---ETAHTSTVLTATATTTGATGSVATPS--STPGTAHTTKVP 2745

Query: 561  SGTTTKITTIPMTS-----KPNVIVVQKTT----GKGTTIQGLPGKNVVTTLLNAGGEKT 611
            + TTT  T  P +S      P V +   TT    G   T   +PG     T+L      T
Sbjct: 2746 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT----T 2801

Query: 612  IQTVPTG--AKPAILTATRPIT-------KMIVTQPKGIGSTVQPAAKIIPTKIVYGQQG 662
              TV TG  A P+  T T   T        M  T  + +  +     +   T    G  G
Sbjct: 2802 TTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILG 2861

Query: 663  KTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSS 722
             T +  +P  VT      +  T Q  T  L      +    S    G   P + T +S +
Sbjct: 2862 TTHI-TEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRT 2920

Query: 723  STESSQS 729
            +  ++ S
Sbjct: 2921 TATATPS 2927



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 97/419 (23%), Positives = 149/419 (35%), Gaps = 56/419 (13%)

Query: 270  TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
            TT TTT+      T  S+     IL++    A VT  VPT   A+ +       T   S+
Sbjct: 3079 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVT--VPTGSTATASSTQATAGTPHVST 3136

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRL---PSP 386
              +  +  SS +TP   P T      + ST +   +T    + +S++    TRL    +P
Sbjct: 3137 TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 3196

Query: 387  KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKP 446
             + +S  T   +  P+    S               VA PS              PG   
Sbjct: 3197 TATMSTATP--SSTPETVHTSTVLTTTATTTGATGSVATPSST------------PGTAH 3242

Query: 447  TIQIKQESGVKI-ITQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTKLVTT 502
            T ++   +      T    P      PV   T T PT+  S +   S  G   T  ++TT
Sbjct: 3243 TTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTT 3302

Query: 503  PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT-VVPKSLATLGGKIISSNIVS 561
             T T AT          G M ATP ++T    TSG+  T  VP + AT  G+ +S +   
Sbjct: 3303 TTTTVAT----------GSM-ATPSSST---QTSGTTHTPPVPNTTATTHGRSLSPSSPH 3348

Query: 562  GTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKP 621
               T  T+    +     + + +TG   T     G    +T   +    + +T  +   P
Sbjct: 3349 TVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP 3408

Query: 622  AILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
                          T P    +T +  A   P+K       +T  L+   P +   T V
Sbjct: 3409 G------------TTTPGHTRATSRTTATATPSKT------RTSTLLPSSPTSAPITTV 3449



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 128/609 (21%), Positives = 213/609 (34%), Gaps = 85/609 (13%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P   P+TA T T             S+  P+ T          T+TT+  T+T  PS S 
Sbjct: 2703 PSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT--PSSSP 2760

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223
             T  +P P   ++       GSTV   S+  +           T  ++ S          
Sbjct: 2761 GTALTP-PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGS---------M 2810

Query: 224  VVPVSKTITVPVSGSPKMSNIMQSI-ANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVT 282
              P S T T   + +P + N M +    SLPP  SP  +     S  +    T  +   +
Sbjct: 2811 ATPSSSTQTSGTTHTPPVPNTMATTHGRSLPP-SSPHTVRTAWTSATSGILGTTHITEPS 2869

Query: 283  TSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSST 342
            T  S T      +  H+  A++   P+S    TT+ PP   T +     + S + ++++T
Sbjct: 2870 TVTSHTLAATTGTTQHSTPALSSPHPSS---RTTESPPSPGTTTPGHTTATSRT-TATAT 2925

Query: 343  PSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP---------KSLVSAP 393
            PS    +  + +  +S P   + T+      +  +      P P          S + A 
Sbjct: 2926 PSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA 2985

Query: 394  TQILAQFP-------KQHQQSPKQQLYQVQQ---------QTQQQVAQPSPVSHQQ---- 433
               + + P       +     P ++L QV +         + ++QV +     + +    
Sbjct: 2986 GGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVF 3045

Query: 434  --QPQQSPLPPGIKPTIQIKQESGVK-IITQQVQPSKILPKPVTATLPTSSNSPIMVVSS 490
                   P  P    T       G   I+T+    +       +   P+S+     +++ 
Sbjct: 3046 CCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTE 3105

Query: 491  NGAIMTTKLVTTPTGTQA----------------TYTRPTVSPSIGRMAATPGAATYV-- 532
                 TT  VT PTG+ A                T T PTV+ S     ++PG AT +  
Sbjct: 3106 PS---TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPA 3162

Query: 533  -----KTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGK 587
                  T + +  T +P S  +LG      +  +  T  ++T   +S P  +        
Sbjct: 3163 LRSTATTPTATSFTAIPSS--SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT 3220

Query: 588  GTTIQGLPGKNVV--TTLLNAGGEKTIQTVPTG--AKPAI---LTATRPITKMIVTQPKG 640
              T  G  G      +T   A   K + T  TG  A P+       T P+     T P  
Sbjct: 3221 TATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTT 3280

Query: 641  IGSTVQPAA 649
             GSTV P++
Sbjct: 3281 RGSTVTPSS 3289



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 94/423 (22%), Positives = 153/423 (36%), Gaps = 62/423 (14%)

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITA 325
            PST  T++T       +++P +T++    + +    A T    T      T  PP V+T 
Sbjct: 2579 PSTPATSSTATP----SSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 2634

Query: 326  SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLP- 384
            + ++     +  SS +TPS  P T      + ST +   +T    + +S++    TRL  
Sbjct: 2635 TATT----PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQ 2690

Query: 385  --SPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +P + +S  T   +  P+    S               VA PS              P
Sbjct: 2691 TTTPTATMSTATP--SSTPETAHTSTVLTATATTTGATGSVATPSST------------P 2736

Query: 443  GIKPTIQIKQESGVKII-TQQVQPSKILPKPV---TATLPTSSNSPIMVVSSNGAIMTTK 498
            G   T ++   +      T    P   L  PV   T T PT+  S +   S  G   T  
Sbjct: 2737 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTAT 2796

Query: 499  LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT-VVPKSLATLGGKIISS 557
            ++TT T T AT          G M ATP ++T    TSG+  T  VP ++AT  G+ +  
Sbjct: 2797 VLTTTTTTVAT----------GSM-ATPSSST---QTSGTTHTPPVPNTMATTHGRSLPP 2842

Query: 558  NIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPT 617
            +      T  T+          + + +T    T+    G    +T   +    + +T  +
Sbjct: 2843 SSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTES 2902

Query: 618  GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677
               P              T P    +T +  A   P+K       +T  L+   P +   
Sbjct: 2903 PPSPG------------TTTPGHTTATSRTTATATPSKT------RTSTLLPSSPTSAPI 2944

Query: 678  TVV 680
            T V
Sbjct: 2945 TTV 2947



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/390 (22%), Positives = 150/390 (38%), Gaps = 47/390 (12%)

Query: 108  PQTAFTVTANAVANA---AIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIA 164
            P T  TVT    + A   + Q  A  P  + T +   V    TS+ +TP S+P  + ++ 
Sbjct: 3106 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV----TSSKATPFSSPGTATALP 3161

Query: 165  TVKSPRPASPASNVVVLPSGS--TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPK 222
             ++S      A++   +PS S  T + +      +   P     T + SS+P   + V  
Sbjct: 3162 ALRSTATTPTATSFTAIPSSSLGTTWTR----LSQTTTPTATMSTATPSSTP---ETVHT 3214

Query: 223  AVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVT 282
            + V  +   T   +GS    +     A     H + V  T T   T T +++      + 
Sbjct: 3215 STVLTTTATTTGATGSVATPSSTPGTA-----HTTKVLTTTTTGFTATPSSSPGTARTLP 3269

Query: 283  TSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSST 342
               S+T  P     +   +++     T  + +TT     V T S ++  S++ +  ++ T
Sbjct: 3270 VWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTT--TTTVATGSMATPSSSTQTSGTTHT 3327

Query: 343  PSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPK 402
            P P+PNT A T   S +PS   +      S ++  + +T +  P +  S           
Sbjct: 3328 P-PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS----------- 3375

Query: 403  QHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQ 462
                +P       Q  T   ++ P P S   +  +SP  PG       +  S     T  
Sbjct: 3376 ---HTPAATTGTTQHST-PALSSPHPSS---RTTESPPSPGTTTPGHTRATSRT---TAT 3425

Query: 463  VQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
              PSK     +  + PTS  +PI  V + G
Sbjct: 3426 ATPSKTRTSTLLPSSPTS--APITTVVTMG 3453



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 92/432 (21%), Positives = 148/432 (34%), Gaps = 78/432 (18%)

Query: 147  TSTTSTPTSTP--------VPSGSIATVKSPRPASPASN--------------VVVLPSG 184
            TS+T+TP+STP        + + +  T  +   A+P+S                V +P+G
Sbjct: 4205 TSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 4264

Query: 185  STVYVKSVSCSDEDEKPRKRRRT---NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKM 241
            ST    S   +           T    SS ++P        A+  +  T T P + S   
Sbjct: 4265 STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATS--- 4321

Query: 242  SNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYA 301
                     ++P   S +  T+T+ S  TT T T      +++P +     +L+ +    
Sbjct: 4322 -------FTAIP--SSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTT 4372

Query: 302  AVTKLVPT-SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTP------SPIPNTVAVTA 354
              T  V T S    T     V  T +    V+ SSS  ++ TP      +  P T   T 
Sbjct: 4373 RATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTV 4432

Query: 355  VVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQ 414
              SS P    +      +T+ +   S   PS  +  S  T                    
Sbjct: 4433 TPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTH------------------- 4473

Query: 415  VQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT 474
                    V   +  +H +    SP  P    T      SG    T   +PS        
Sbjct: 4474 -----TPPVPNTTATTHGR--SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 4526

Query: 475  ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534
            AT  T+ +S   + S + +  TT+   +P  T   +T  T        + T   AT  KT
Sbjct: 4527 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTAT--------SRTTATATPSKT 4578

Query: 535  TSGSIITVVPKS 546
             + +++   P S
Sbjct: 4579 RTSTLLPSSPTS 4590



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 90/383 (23%), Positives = 143/383 (37%), Gaps = 40/383 (10%)

Query: 297  SHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356
            ++ +   T    ++ + S+T     ++T   ++  +  S+GS++ TPS  P T  +    
Sbjct: 3048 NYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTA-TPSSTPGTTWILTEP 3106

Query: 357  SSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQ 416
            S+T +V + T +   ++S    A T  P   +  + PT   ++            L    
Sbjct: 3107 STTATVTVPTGSTATASSTQATAGT--PHVSTTATTPTVTSSKATPFSSPGTATAL---- 3160

Query: 417  QQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV--- 473
               +     P+  S    P  S      + +      + +   T    P  +    V   
Sbjct: 3161 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT 3220

Query: 474  TATLPTSSNSPIMVVSSNGAIMTTK-LVTTPTGTQATYTRPTVSPSIGRMAATPGAATYV 532
            TAT   ++ S     S+ G   TTK L TT TG  AT   P+ SP   R      + T  
Sbjct: 3221 TATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTAT---PSSSPGTARTLPVWISTTTT 3277

Query: 533  KTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQ 592
             TT GS  TV P S+    G   +  +++ TTT + T  M +  +      T   GTT  
Sbjct: 3278 PTTRGS--TVTPSSIP---GTTHTPTVLTTTTTTVATGSMATPSS-----STQTSGTTHT 3327

Query: 593  GLPGKNVVTT---LLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAA 649
                    TT    L+     T++T  T A    L  T       +T+P   G++  PAA
Sbjct: 3328 PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH------ITEP-STGTSHTPAA 3380

Query: 650  KIIPTKIVYGQQGKTQVLIKPKP 672
                T      Q  T  L  P P
Sbjct: 3381 TTGTT------QHSTPALSSPHP 3397



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 88/432 (20%), Positives = 146/432 (33%), Gaps = 78/432 (18%)

Query: 147  TSTTSTPTSTP--------VPSGSIATVKSPRPASPASN--------------VVVLPSG 184
            TS+T+ P+STP        + + +  T  +   A+P+S                V +P+G
Sbjct: 3058 TSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 3117

Query: 185  STVYVKSVSCSDEDEKPRKRRRT---NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKM 241
            ST    S   +           T    SS ++P        A+  +  T T P + S   
Sbjct: 3118 STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATS--- 3174

Query: 242  SNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYA 301
                     ++P   S +  T+T+ S  TT T T      +++P +     +L+ +    
Sbjct: 3175 -------FTAIP--SSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTT 3225

Query: 302  AVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPI-------PNTVAVTA 354
              T  V T      T     V+T + +   +  SS   ++   P+       P T   T 
Sbjct: 3226 GATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTV 3285

Query: 355  VVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQ 414
              SS P    +      +T+ +   S   PS  +  S  T                    
Sbjct: 3286 TPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTH------------------- 3326

Query: 415  VQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT 474
                    V   +  +H +    SP  P    T      SG    T   +PS        
Sbjct: 3327 -----TPPVPNTTATTHGR--SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 3379

Query: 475  ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534
            AT  T+ +S   + S + +  TT+   +P  T   +TR T        + T   AT  KT
Sbjct: 3380 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRAT--------SRTTATATPSKT 3431

Query: 535  TSGSIITVVPKS 546
             + +++   P S
Sbjct: 3432 RTSTLLPSSPTS 3443



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 92/381 (24%), Positives = 138/381 (36%), Gaps = 38/381 (9%)

Query: 299  NYAAVTKLVPTSVIASTTQKPPVV-ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS 357
            NY        TS  A+ +  P    I    ++  + + S  S++TPS  P T  +    S
Sbjct: 4195 NYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPS 4254

Query: 358  STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQ 417
            +T +V + T +   ++S    A T  P   +  + PT   ++            L     
Sbjct: 4255 TTATVTVPTGSTATASSTQATAGT--PHVSTTATTPTVTSSKATPFSSPGTATAL----P 4308

Query: 418  QTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPV---T 474
              +     P+  S    P  S      + +      + +   T    P       V   T
Sbjct: 4309 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 4368

Query: 475  ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534
            AT   ++ S     S+ G   TTK+ TT T T  T T P+ SP   R      + T   T
Sbjct: 4369 ATTTRATGSVATPSSTPGTAHTTKVPTTTT-TGFTVT-PSSSPGTARTPPVWISTTTTPT 4426

Query: 535  TSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGL 594
            TSGS  TV P S+    G   +  +++ TTT + T  M +  +      T   GTT    
Sbjct: 4427 TSGS--TVTPSSVP---GTTHTPTVLTTTTTTVATGSMATPSS-----STQTSGTTHTPP 4476

Query: 595  PGKNVVTT---LLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI 651
                  TT    L+     T++T  T A    L  T       +T+P   G++  PAA  
Sbjct: 4477 VPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH------ITEP-STGTSHTPAATT 4529

Query: 652  IPTKIVYGQQGKTQVLIKPKP 672
              T      Q  T  L  P P
Sbjct: 4530 GTT------QHSTPALSSPHP 4544



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 177/869 (20%), Positives = 299/869 (34%), Gaps = 131/869 (15%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P   P+T  T T             S+  P+ T          T+TT+  T+T  PS S 
Sbjct: 3205 PSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTAT--PSSSP 3262

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223
             T ++  P   ++       GSTV   S+  +           T  ++ S          
Sbjct: 3263 GTART-LPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGS---------M 3312

Query: 224  VVPVSKTITVPVSGSPKMSNIMQSI-ANSLPPHMSP--VKITFTKPSTQTTNTTTQKVII 280
              P S T T   + +P + N   +    SL P  SP  V+  +T  ++ T  TT   +  
Sbjct: 3313 ATPSSSTQTSGTTHTPPVPNTTATTHGRSLSP-SSPHTVRTAWTSATSGTLGTT--HITE 3369

Query: 281  VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340
             +T  S T      +  H+  A++   P+S    TT+ PP   T +     + S + +++
Sbjct: 3370 PSTGTSHTPAATTGTTQHSTPALSSPHPSS---RTTESPPSPGTTTPGHTRATSRT-TAT 3425

Query: 341  STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP---------KSLVS 391
            +TPS    +  + +  +S P   + T+      +  +      P P          S + 
Sbjct: 3426 ATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 3485

Query: 392  APTQILAQFP-------KQHQQSPKQQLYQVQQ---------QTQQQVAQPSPVSHQQ-- 433
            A    + + P       +     P ++L QV +         + ++QV +     + +  
Sbjct: 3486 AAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 3545

Query: 434  ----QPQQSPLPPGIKPTIQIKQESGVK-IITQQVQPSKILPKPVTATLPTSSNSPIMVV 488
                     P  P    T       G   I+T+Q            AT   ++ S  +  
Sbjct: 3546 VFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQT---------TAATTTATTGSTAIPS 3596

Query: 489  SSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLA 548
            S+ G     K++T      +T T PT + S    +++P  A    TT   + +   KS A
Sbjct: 3597 STPGTAPPPKVLT------STATTPTATSSKATSSSSPRTA----TTLPVLTSTATKSTA 3646

Query: 549  TLGGKIISSNI-VSGTTTKITTIPM--------------TSKPNVIVVQKTTGKGT---- 589
            T    I S  +  +GT  + TT PM              T    V+  + TT + T    
Sbjct: 3647 TSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMS 3706

Query: 590  TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAA 649
            T    PG   + T L      T  T PT        ++ P T  I+T+P    +   P  
Sbjct: 3707 TPSSTPGTTWILTELTTAATTTAATGPTAT-----PSSTPGTTWILTEPSTTATVTVPTG 3761

Query: 650  KIIPTKIVYGQQGKTQVLIK----PKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSS 705
                        G  +VL      P  ++ +AT  S          L+  +    A + +
Sbjct: 3762 STATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVT 3821

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSE--HEIAMETSPTIIYQ 763
                         SSS  T  ++ SQ + P   +  +      E  H   + T+ T   +
Sbjct: 3822 A----------IPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTR 3871

Query: 764  DVSSESQSATSTIKALLELQQTTVKEKLESKPRQP--TIDLSQMAVPIQMTQEKRHSPES 821
               S +  +++   A      TT      + P     T     + +    T   R S  +
Sbjct: 3872 ATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVT 3931

Query: 822  PSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQ 881
            PS ++  +   A  +TT  T   T           + P   +Q   T       + TAT 
Sbjct: 3932 PS-SIPGTTHTATVLTTTTTTVAT--------GSMATPSSSTQTSGTTHTPPVPNTTATT 3982

Query: 882  TSVVVKSIPASSPGAITHIMQQALSSHTA 910
                 +S+P SSP    H ++ A +S T+
Sbjct: 3983 HG---RSLPPSSP----HTVRTAWTSATS 4004



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 58/253 (22%), Positives = 98/253 (38%), Gaps = 25/253 (9%)

Query: 104  PRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSI 163
            P   P+T  T T             S+  P+ T          T+TT+  T+T  PS S 
Sbjct: 5025 PSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT--PSSSP 5082

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPV-----VLK 218
             T  +P   +P S +  + + ST      S          R   ++++ S       +L 
Sbjct: 5083 GTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILT 5142

Query: 219  EVPKAVVPVSKT-ITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQK 277
            E+       + T  T  +S +P  + I+    +++   M P   T T  ST  T  T + 
Sbjct: 5143 ELTTTATTTAATGSTATLSSTPGTTWILTE-PSTIATVMVPTGSTATASSTLGTAHTPKV 5201

Query: 278  VIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSN-SSS 336
            V  + T P++T                  VP+S    TT+ P V+ ++  +  VS  SSS
Sbjct: 5202 VTTMATMPTAT---------------ASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSS 5246

Query: 337  GSSSSTPSPIPNT 349
              ++  P+  P++
Sbjct: 5247 VLTTLRPTGFPSS 5259



 Score = 37.7 bits (86), Expect = 0.074
 Identities = 47/185 (25%), Positives = 73/185 (39%), Gaps = 20/185 (10%)

Query: 1065 PKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQP-PTVTKITGGS 1123
            PK+   P T  +  S  A+S     +    P++T  S+ TK T     P P+ T  T G+
Sbjct: 4752 PKVLTSPATTPTATSSKATSSSSPRTATTLPVLT--STATKSTATSVTPIPSSTLGTTGT 4809

Query: 1124 SVPKLTSPVTSISPIQAS---EKTAVSDIL--KMSLMEAQIDTNVEH------MIVDPPK 1172
               + T+PV ++S I  S   E T  S +L  K +   A   T+          I+    
Sbjct: 4810 LPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELT 4869

Query: 1173 KALATSMLTGEA---GSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPP 1229
             A  T+  TG      S P T  ++  +  +         + +  ST G   TT  +  P
Sbjct: 4870 TAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG---TTWILTEP 4926

Query: 1230 AVPAT 1234
            +  AT
Sbjct: 4927 STTAT 4931


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 224/1122 (19%), Positives = 394/1122 (35%), Gaps = 201/1122 (17%)

Query: 226  PVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSP 285
            P    I+  +  SP  SN      ++ P      K+  T P+    + TT+ V       
Sbjct: 82   PHDTLISETLLNSPVSSN-----TSTTPTSKFAFKVETTPPTVLVYSATTECVY------ 130

Query: 286  SSTFVPNILSKSHNYAAVTKLVPTSVIAST--TQKPPVVITASQSSLVSNSSSGSSSSTP 343
             ++F+  I   +      T++  TS   ST  TQKP   +T++ S  ++ +  G+S+ T 
Sbjct: 131  PTSFIITISHPTSICVTTTQVAFTSSYTSTPVTQKPVTTVTSTYS--MTTTEKGTSAMTS 188

Query: 344  SPIPNTVAVTAVVSSTPSVVMSTVAQGVST-SAIKMASTRLPSPKSLVSAPTQILAQFPK 402
            SP   T   T +V+ TPS V +T     +T S+    + R P P   +   T        
Sbjct: 189  SPSTTTARETPIVTVTPSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTT-------- 240

Query: 403  QHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQ 462
                                               SP P  +  T++    S   I +  
Sbjct: 241  -----------------------------------SPTP--VFTTLKTAVTSTSPITSSI 263

Query: 463  VQPSKILPKPVTATLPTSSN---SPIMVVSSNGAIMTTKLV------TTPTGTQATYTRP 513
               + +     TA+ PT++N   SP   + S+  +++T+ +      TTP  T  T    
Sbjct: 264  TSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPVLSTETITSGITNTTPLSTLVTTLPT 323

Query: 514  TVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMT 573
            T+S S      TP + T   T+  S +T           KI  S  ++GT +  T++P T
Sbjct: 324  TISRS------TPTSETTYPTSPTSTVT-------DSTTKIAYSTSMTGTLSTETSLPPT 370

Query: 574  SKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRP-ITK 632
            S         TT   TT    P  N+VTT        T     +     + + + P  T 
Sbjct: 371  SSS-----LPTTETATT----PMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTS 421

Query: 633  MIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETL 692
             I T      ST +  +    TK    +      LI     T  +T  S  +    TET 
Sbjct: 422  SITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHST-PSFTSSITTTETT 480

Query: 693  QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEI 752
              ++R   +  ++ +      +++T SS ++TE+                     + H  
Sbjct: 481  SHSARSFTSSITTTETTSHNTRSFT-SSITTTET---------------------NSHST 518

Query: 753  AMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMT 812
               TS     +  S  + S +S+I        TT +  L S P           +   +T
Sbjct: 519  TSFTSSITTTETTSHSTPSFSSSI--------TTTETPLHSTP----------GLTSWVT 560

Query: 813  QEKRHSPESPSIAVVESELVAEYITTERTDEGTE-VAFPLLVSHRSQPQQPSQPQRTLLQ 871
              K  S  +P        L +   TTE T   T      +  +  +    PS    T+  
Sbjct: 561  TTKTTSHITPG-------LTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYS 613

Query: 872  HVAQSQTA-----TQTSVVVKSIPASSPGAITHIMQQALSSHT---AFTKHSEELGTEEG 923
             V+ S TA     T +   V   P +     T I   +L + T     T  S    T+  
Sbjct: 614  TVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFP 673

Query: 924  EV-EEMDTLDPQTGLFYRSALTQS-QSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIH 981
             +  ++ TL  +T +   S   QS +++     + P +   ++ ++  +        T  
Sbjct: 674  SIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSI 733

Query: 982  LQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQ 1041
            +   +   + P +         LT     Q  P P    T     + D    TL    P 
Sbjct: 734  VVIPETPTQTPPV---------LTSATGTQTSPAP----TTVTFGSTDSSTSTLHTLTPS 780

Query: 1042 TVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGS 1101
            T +  +   +T Q+P    + +   +   P TP  Q SL ++SE  T S       T   
Sbjct: 781  TALSTIV--STSQVP--IPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAI 836

Query: 1102 SVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDT 1161
              +  T      PT+   +  SS         SI+P+ +   T +  +     + +  + 
Sbjct: 837  LTSFSTIIWSSTPTIIMSSSPSS--------ASITPVFS---TTIHSVPSSPYIFSTENV 885

Query: 1162 NVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMAN-STPQQQKCRESCSSPSTVGSS 1220
                +   P   + AT+  +  + SL +    +   +  S P    C      P T+  +
Sbjct: 886  GSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLPSTTPC------PGTITIT 939

Query: 1221 LTTRKIDPPAVPATGQFMRIQNVGQKKAEESP-AEIIIQAIPQYAIPCHSSSNVVVEPSG 1279
            +         VPA+     ++     +A   P   + +       + C +S ++    + 
Sbjct: 940  I---------VPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTT 990

Query: 1280 LLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAER 1321
             ++    TS  + + E+++  +  SST  GT P+ +  ++ R
Sbjct: 991  YMD----TSSMMPESESSISPNASSSTGTGTVPTNTVFTSTR 1028



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 165/839 (19%), Positives = 290/839 (34%), Gaps = 148/839 (17%)

Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
           T+ TST + T    G+ A   SP   +     +V     TV   SVS +D          
Sbjct: 168 TTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIV-----TVTPSSVSATDTTFHTTISST 222

Query: 207 TNSSSSSPVVLKEVPKAVVP--------VSKTITVPVSGSPKMSNIMQSIANSLPPH--- 255
           T ++  +P+    +     P         + T T P++ S   +N + S+  +       
Sbjct: 223 TRTTERTPLPTGSIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTAT 282

Query: 256 ---MSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFV---PNILSKSHNYAAVT-KLVP 308
               SP +   +     +T T T    I  T+P ST V   P  +S+S   +  T    P
Sbjct: 283 NTLSSPTRTILSSTPVLSTETITSG--ITNTTPLSTLVTTLPTTISRSTPTSETTYPTSP 340

Query: 309 TSVIASTTQKPPVVITASQSSLVSNSSS--GSSSSTP------SPIPNTVAVTAVVS--S 358
           TS +  +T K  +  + S +  +S  +S   +SSS P      +P+ N V  T  +S  S
Sbjct: 341 TSTVTDSTTK--IAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHS 398

Query: 359 TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418
           TPS   ST+   V++ +    ++ + + ++   +  +  + F      S +   +     
Sbjct: 399 TPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLIT 458

Query: 419 TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP 478
           T +  +  +P                         S +         ++     +T T  
Sbjct: 459 TTETTSHSTP----------------------SFTSSITTTETTSHSARSFTSSITTTET 496

Query: 479 TSSN----SPIMVVSSNGAIMTTKLVTTPTGTQAT-YTRPTVSPSIGR----MAATPGAA 529
           TS N    +  +  +   +  TT   ++ T T+ T ++ P+ S SI      + +TPG  
Sbjct: 497 TSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLT 556

Query: 530 TYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGT 589
           ++V TT                    +S+I  G T+ ITT   TS          T   T
Sbjct: 557 SWVTTTK------------------TTSHITPGLTSSITTTETTSHSTPGFTSSITTTET 598

Query: 590 TIQGLPGKNVVTTLLNAGGEKTIQT----------VPTGAKPAILTATRPITKMIVTQPK 639
           T +  P  +  T         T  T           PT   P+ L+   P T +    P 
Sbjct: 599 TSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPS 658

Query: 640 GIGS----TVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQA 695
            +G+    T       IPT I       + +  +   ++   ++ S +T  LV  T    
Sbjct: 659 SVGTSTSLTTTTDFPSIPTDI-------STLPTRTHIISSSPSIQSTETSSLVGTTSPTM 711

Query: 696 SRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAME 755
           S V                     +   TE++  S  S  +V +           E   +
Sbjct: 712 STVR-------------------MTLRITENTPISSFSTSIVVI----------PETPTQ 742

Query: 756 TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEK 815
           T P +     +  S + T+      +   +T+     S      +  SQ+ +P   +   
Sbjct: 743 TPPVLTSATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTL 802

Query: 816 RHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQ 875
           + +P +PS+    S       TTE    G+     +L S  S     S P   +    + 
Sbjct: 803 QTTPSTPSLQT--SLTSTSEFTTESFTRGSTSTNAILTSF-STIIWSSTPTIIMSSSPSS 859

Query: 876 SQTATQTSVVVKSIPAS---------SPGAITHIMQQALSSHTAFTKHSEELGTEEGEV 925
           +      S  + S+P+S            +IT     + S+ T+ +  S  L T   E+
Sbjct: 860 ASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEI 918



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 191/871 (21%), Positives = 316/871 (36%), Gaps = 135/871 (15%)

Query: 108  PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK 167
            P   FT    AV + +       P+ +   S   V  S T+T S PT+T   S    T+ 
Sbjct: 242  PTPVFTTLKTAVTSTS-------PITSSITSTNTVT-SMTTTASQPTATNTLSSPTRTIL 293

Query: 168  SPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPV 227
            S  P      +    + +T     V+             T  S S+P      P +    
Sbjct: 294  SSTPVLSTETITSGITNTTPLSTLVTTLP----------TTISRSTPTSETTYPTSPTST 343

Query: 228  SKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSS 287
                T  ++ S  M+  + S   SLPP  S +      P+T+T  T    ++  TT  SS
Sbjct: 344  VTDSTTKIAYSTSMTGTL-STETSLPPTSSSL------PTTETATTPMTNLVTTTTEISS 396

Query: 288  TFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIP 347
               P+  S +      +   P    + TT + P   T   +S  +N+ + +S  +PS   
Sbjct: 397  HSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKT-TSHRSPSFTS 455

Query: 348  NTVAVTAVVSSTPSVVMS-TVAQGVS------TSAIKMASTRLPSPKSLVSAPTQILAQF 400
                      STPS   S T  +  S      TS+I    T   + +S  S+ T    + 
Sbjct: 456  LITTTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSIT--TTET 513

Query: 401  PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGI-------KPTIQIKQE 453
                  S    +   +  +    +  S ++  + P  S   PG+       K T  I   
Sbjct: 514  NSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHS--TPGLTSWVTTTKTTSHITPG 571

Query: 454  SGVKIITQQVQPSKI--LPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYT 511
                I T +            +T T  TS ++P +  SS+    T    TT   +  T +
Sbjct: 572  LTSSITTTETTSHSTPGFTSSITTTETTSESTPSL--SSSTIYSTVSTSTTAITSHFTTS 629

Query: 512  RPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTI 570
               V+P+      TP + +T + TT  S+ T+ P S+ T      +++  S   T I+T+
Sbjct: 630  ETAVTPT----PVTPSSLSTDIPTT--SLRTLTPSSVGTSTSLTTTTDFPS-IPTDISTL 682

Query: 571  P-----MTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILT 625
            P     ++S P++   + ++  GTT    P  + V   L       I +  T     ++ 
Sbjct: 683  PTRTHIISSSPSIQSTETSSLVGTT---SPTMSTVRMTLRITENTPISSFSTSI--VVIP 737

Query: 626  ATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQ-QGKTQVLIKPKPVTFQATVVSEQT 684
             T   T  ++T     G+   PA    PT + +G     T  L    P T  +T+VS  T
Sbjct: 738  ETPTQTPPVLT--SATGTQTSPA----PTTVTFGSTDSSTSTLHTLTPSTALSTIVS--T 789

Query: 685  RQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSS----SSST---------------- 724
             Q+   +   ++        S+Q        +T  S    S+ST                
Sbjct: 790  SQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTP 849

Query: 725  ----ESSQSSQDSQPV----VHVIASRRQDWSEHEI---AMETSPTIIYQDVSSESQSAT 773
                 SS SS    PV    +H + S    +S   +   ++   P++     +S S +++
Sbjct: 850  TIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSS 909

Query: 774  STIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVA 833
            S   AL E+   +      + P   TI ++ +             P SP+   VE +   
Sbjct: 910  SLTTALTEITPFSYISLPSTTPCPGTITITIV-------------PASPTDPCVEMD--- 953

Query: 834  EYITTERTDEGTE--VAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPA 891
               +TE T   T     FP      + P   S  Q TL  ++  S      S++ +S  +
Sbjct: 954  --PSTEATSPPTTPLTVFPFTTEMVTCPTSIS-IQTTLTTYMDTS------SMMPESESS 1004

Query: 892  SSPGAITHIMQQALSSHTAFTKHSEELGTEE 922
             SP A +      + ++T FT  S  L T E
Sbjct: 1005 ISPNASSSTGTGTVPTNTVFT--STRLPTSE 1033



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 146/756 (19%), Positives = 272/756 (35%), Gaps = 83/756 (10%)

Query: 110  TAFTVTANAVANAAIQHNA----SLPVPAETGSKEVVCY--SYTSTTSTPTSTPVPSGSI 163
            +A + T++        HN     S     ET S     +  S T+T +T  STP  S SI
Sbjct: 483  SARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSI 542

Query: 164  ATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKA 223
             T ++P  ++P     V  + +T ++     S           T   +SS    +   ++
Sbjct: 543  TTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTSES 602

Query: 224  VVPVSKTI---TVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVII 280
               +S +    TV  S +   S+   S     P  ++P  ++   P+T     T   V  
Sbjct: 603  TPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGT 662

Query: 281  VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340
             T+  ++T  P+I +        T ++ +S    +T+   +V T S +      +   + 
Sbjct: 663  STSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITE 722

Query: 341  STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQF 400
            +TP    +T  V    + T +  + T A G  TS         P+P ++    T   +  
Sbjct: 723  NTPISSFSTSIVVIPETPTQTPPVLTSATGTQTS---------PAPTTVTFGSTD--SST 771

Query: 401  PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIIT 460
               H  +P   L  +   +Q     P P +H    Q +P  P ++ ++    E   +  T
Sbjct: 772  STLHTLTPSTALSTIVSTSQ----VPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFT 827

Query: 461  QQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT----PTGTQATYTRPTVS 516
            +    +  +    +  + +S+ + IM  S + A +T    TT    P+      T    S
Sbjct: 828  RGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGS 887

Query: 517  PSI-GRMAATPGAATYVKTTSGSIIT----VVPKSLATL------GGKII---------- 555
             SI G  + +  A T   +TS S+ T    + P S  +L       G I           
Sbjct: 888  ASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTD 947

Query: 556  -------SSNIVSGTTTKITTIPMTSK----PNVIVVQKTTGKGTTIQGLPGKNVVTTLL 604
                   S+   S  TT +T  P T++    P  I +Q T         +  ++  +   
Sbjct: 948  PCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSSMMPESESSISP 1007

Query: 605  NAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKT 664
            NA       TVPT     + T+TR  T            T    + +IP  +     G +
Sbjct: 1008 NASSSTGTGTVPTN---TVFTSTRLPT----------SETWLSNSSVIPLPL----PGVS 1050

Query: 665  QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724
             + +  KP +   T++  +T    T      +R +E   ++ Q     P   T   ++  
Sbjct: 1051 TIPLTMKPSSSLPTIL--RTSSKSTHPSPPTTRTSETPVATTQ----TPTTLTSRRTTRI 1104

Query: 725  ESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ 784
             S  ++Q +             W + + A     +     + +  Q+         +   
Sbjct: 1105 TSQMTTQSTLTTTAGTCDNGGTWEQGQCACLPGFSGDRCQLQTRCQNGGQWDGLKCQCPS 1164

Query: 785  TTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPE 820
            T      E    Q  +D+ +  V ++++ +++ SP+
Sbjct: 1165 TFYGSSCEFAVEQVDLDVVETEVGMEVSVDQQFSPD 1200


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+ + +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 206/1094 (18%), Positives = 367/1094 (33%), Gaps = 104/1094 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPII---TQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVT 1133
              +  A SE  TAS          T GS  T  +  G +  T       +S P      T
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET 1243

Query: 1134 SISPIQASEKTAVS 1147
            + + I  SE T  S
Sbjct: 1244 NTAFIIGSETTIAS 1257



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 718  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 777  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 952  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011

Query: 927  EMDTL 931
            E  T+
Sbjct: 1012 ETTTV 1016



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++        +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 122/629 (19%), Positives = 221/629 (35%), Gaps = 58/629 (9%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  +  S  T +     K    S +         T  +    S    +     +    
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT---- 1148

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502
                   + + + V  I  +   S       T T  ++  S     S+ G+  TT    +
Sbjct: 1149 ------TVSETTTVSTIGSEATTSSAAGSEATTT--STEGSETTTASTAGSETTT---AS 1197

Query: 503  PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562
              G++   T  + + S    A+T G+ T    T+GS  T  P S    G +  ++ I+  
Sbjct: 1198 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1251

Query: 563  TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617
             TT  +T  +      +   +TT    T  G    +      T +L    + +IQ +  T
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311

Query: 618  GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677
                   T TR      VT   G+  T   A+  +P  IV    G     +     T   
Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1370

Query: 678  TV--VSEQTRQLVTETLQQASRVAEAGNS 704
             V   +  TR+  + T Q+   V+   N+
Sbjct: 1371 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1399



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%)

Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
           TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
           SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61  SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
             +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
           SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
           S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
               S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                         +    T    +  S+T+T ++   ++  AS+ G+ T       S  
Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 909 TAFTKHSEELGT 920
           T  +    E  T
Sbjct: 394 TTVSTTGSETTT 405


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+ + +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136
              +  A SE  TAS       T GS  T  +  G +  T       +S P      T+ +
Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236

Query: 1137 PIQASEKTAVS 1147
             I  SE T  S
Sbjct: 1237 FIIGSETTIAS 1247



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 718  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 777  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 952  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011

Query: 927  EMDTL 931
            E  T+
Sbjct: 1012 ETTTV 1016



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++        +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 111/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437
              +  +  S  T +     K    S +         T  +    S    +         +
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152

Query: 438  SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497
            +     I         +G +  T   + S+      T T  T+ +      ++     T 
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1206

Query: 498  KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557
                + T T  T    T +PS              +TT  S  ++ P + +  G +  + 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266

Query: 558  NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616
            +I  SG T   TT+  T+    ++ + T      I   P     TT        ++   P
Sbjct: 1267 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1323

Query: 617  TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676
                    +A       IV    G+G++   A+    T   +G +  T    +P   TFQ
Sbjct: 1324 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1378

Query: 677  AT 678
             T
Sbjct: 1379 ET 1380



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%)

Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
           TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
           SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61  SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
             +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
           SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
           S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
               S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                         +    T    +  S+T+T ++   ++  AS+ G+ T       S  
Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 909 TAFTKHSEELGT 920
           T  +    E  T
Sbjct: 394 TTVSTTGSETTT 405


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+ + +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136
              +  A SE  TAS       T GS  T  +  G +  T       +S P      T+ +
Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236

Query: 1137 PIQASEKTAVS 1147
             I  SE T  S
Sbjct: 1237 FIIGSESTIAS 1247



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 718  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 777  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 952  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011

Query: 927  EMDTL 931
            E  T+
Sbjct: 1012 ETTTV 1016



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++        +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 110/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437
              +  +  S  T +     K    S +         T  +    S    +         +
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152

Query: 438  SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497
            +     I         +G +  T   + S+      T T  T+ +      ++     T 
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1206

Query: 498  KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557
                + T T  T    T +PS              ++T  S  ++ P + +  G +  + 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTV 1266

Query: 558  NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616
            +I  SG T   TT+  T+    ++ + T      I   P     TT        ++   P
Sbjct: 1267 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1323

Query: 617  TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676
                    +A       IV    G+G++   A+    T   +G +  T    +P   TFQ
Sbjct: 1324 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1378

Query: 677  AT 678
             T
Sbjct: 1379 ET 1380



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%)

Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
           TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
           SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61  SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
             +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
           SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
           S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
               S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                         +    T    +  S+T+T ++   ++  AS+ G+ T       S  
Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 909 TAFTKHSEELGT 920
           T  +    E  T
Sbjct: 394 TTVSTTGSETTT 405


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+ + +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136
              +  A SE  TAS       T GS  T  +  G +  T       +S P      T+ +
Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236

Query: 1137 PIQASEKTAVS 1147
             I  SE T  S
Sbjct: 1237 FIIGSETTIAS 1247



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 718  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 777  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 952  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011

Query: 927  EMDTL 931
            E  T+
Sbjct: 1012 ETTTV 1016



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++        +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 121/629 (19%), Positives = 220/629 (34%), Gaps = 68/629 (10%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  +  S  T +     K    S +         T  +    S    +          
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM--------- 1143

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502
                           + T   + + +      AT  +++ S     S+ G+  TT    +
Sbjct: 1144 -------------TTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTT---AS 1187

Query: 503  PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562
              G++   T  + + S    A+T G+ T    T+GS  T  P S    G +  ++ I+  
Sbjct: 1188 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1241

Query: 563  TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617
             TT  +T  +      +   +TT    T  G    +      T +L    + +IQ +  T
Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1301

Query: 618  GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677
                   T TRP     VT   G+  T   A+  +P  IV    G     +     T   
Sbjct: 1302 PMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1360

Query: 678  TV--VSEQTRQLVTETLQQASRVAEAGNS 704
             V   +  TR+  + T Q+   V+   N+
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1389



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%)

Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
           TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
           SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61  SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
             +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
           SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
           S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
               S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                         +    T    +  S+T+T ++   ++  AS+ G+ T       S  
Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 909 TAFTKHSEELGT 920
           T  +    E  T
Sbjct: 394 TTVSTTGSETTT 405


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+ + +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136
              +  A SE  TAS       T GS  T  +  G +  T       +S P      T+ +
Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236

Query: 1137 PIQASEKTAVS 1147
             I  SE T  S
Sbjct: 1237 FIIGSETTIAS 1247



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 718  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 777  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 952  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011

Query: 927  EMDTL 931
            E  T+
Sbjct: 1012 ETTTV 1016



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++        +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 121/629 (19%), Positives = 220/629 (34%), Gaps = 68/629 (10%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  +  S  T +     K    S +         T  +    S    +          
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM--------- 1143

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502
                           + T   + + +      AT  +++ S     S+ G+  TT    +
Sbjct: 1144 -------------TTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTT---AS 1187

Query: 503  PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562
              G++   T  + + S    A+T G+ T    T+GS  T  P S    G +  ++ I+  
Sbjct: 1188 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1241

Query: 563  TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617
             TT  +T  +      +   +TT    T  G    +      T +L    + +IQ +  T
Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1301

Query: 618  GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677
                   T TRP     VT   G+  T   A+  +P  IV    G     +     T   
Sbjct: 1302 PMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1360

Query: 678  TV--VSEQTRQLVTETLQQASRVAEAGNS 704
             V   +  TR+  + T Q+   V+   N+
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1389



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%)

Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
           TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
           SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61  SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
             +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
           SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
           S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
               S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                         +    T    +  S+T+T ++   ++  AS+ G+ T       S  
Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 909 TAFTKHSEELGT 920
           T  +    E  T
Sbjct: 394 TTVSTTGSETTT 405


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+ + +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 206/1094 (18%), Positives = 367/1094 (33%), Gaps = 104/1094 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPII---TQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVT 1133
              +  A SE  TAS          T GS  T  +  G +  T       +S P      T
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET 1243

Query: 1134 SISPIQASEKTAVS 1147
            + + I  SE T  S
Sbjct: 1244 NTAFIIGSETTIAS 1257



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 718  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 777  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 952  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011

Query: 927  EMDTL 931
            E  T+
Sbjct: 1012 ETTTV 1016



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++        +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 122/629 (19%), Positives = 221/629 (35%), Gaps = 58/629 (9%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  +  S  T +     K    S +         T  +    S    +     +    
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT---- 1148

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502
                   + + + V  I  +   S       T T  ++  S     S+ G+  TT    +
Sbjct: 1149 ------TVSETTTVSTIGSEATTSSAAGSEATTT--STEGSETTTASTAGSETTT---AS 1197

Query: 503  PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562
              G++   T  + + S    A+T G+ T    T+GS  T  P S    G +  ++ I+  
Sbjct: 1198 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1251

Query: 563  TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617
             TT  +T  +      +   +TT    T  G    +      T +L    + +IQ +  T
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311

Query: 618  GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677
                   T TR      VT   G+  T   A+  +P  IV    G     +     T   
Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1370

Query: 678  TV--VSEQTRQLVTETLQQASRVAEAGNS 704
             V   +  TR+  + T Q+   V+   N+
Sbjct: 1371 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1399



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%)

Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
           TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
           SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61  SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
             +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
           SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
           S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
               S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                         +    T    +  S+T+T ++   ++  AS+ G+ T       S  
Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 909 TAFTKHSEELGT 920
           T  +    E  T
Sbjct: 394 TTVSTTGSETTT 405


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+ + +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 206/1094 (18%), Positives = 367/1094 (33%), Gaps = 104/1094 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPII---TQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVT 1133
              +  A SE  TAS          T GS  T  +  G +  T       +S P      T
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET 1243

Query: 1134 SISPIQASEKTAVS 1147
            + + I  SE T  S
Sbjct: 1244 NTAFIIGSETTIAS 1257



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 718  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 777  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 952  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011

Query: 927  EMDTL 931
            E  T+
Sbjct: 1012 ETTTV 1016



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++        +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 122/629 (19%), Positives = 221/629 (35%), Gaps = 58/629 (9%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  +  S  T +     K    S +         T  +    S    +     +    
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT---- 1148

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT 502
                   + + + V  I  +   S       T T  ++  S     S+ G+  TT    +
Sbjct: 1149 ------TVSETTTVSTIGSEATTSSAAGSEATTT--STEGSETTTASTAGSETTT---AS 1197

Query: 503  PTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSG 562
              G++   T  + + S    A+T G+ T    T+GS  T  P S    G +  ++ I+  
Sbjct: 1198 TAGSET--TTASTAGSETTTASTSGSETNTACTTGS-ETSTPSS---AGSETNTAFIIGS 1251

Query: 563  TTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV----VTTLLNAGGEKTIQTVP-T 617
             TT  +T  +      +   +TT    T  G    +      T +L    + +IQ +  T
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311

Query: 618  GAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQA 677
                   T TR      VT   G+  T   A+  +P  IV    G     +     T   
Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP-GIVLNTSGLGTSTMGASSTTSAH 1370

Query: 678  TV--VSEQTRQLVTETLQQASRVAEAGNS 704
             V   +  TR+  + T Q+   V+   N+
Sbjct: 1371 GVRTTTGSTREPTSSTFQETGPVSMGTNT 1399



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%)

Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
           TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
           SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61  SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
             +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
           SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
           S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
               S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                         +    T    +  S+T+T ++   ++  AS+ G+ T       S  
Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 909 TAFTKHSEELGT 920
           T  +    E  T
Sbjct: 394 TTVSTTGSETTT 405


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1125 (19%), Positives = 386/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+ + +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTI-----PMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136
              +  A SE  TAS       T GS  T  +  G +  T       +S P      T+ +
Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236

Query: 1137 PIQASEKTAVS 1147
             I  SE T  S
Sbjct: 1237 FIIGSESTIAS 1247



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 187/905 (20%), Positives = 323/905 (35%), Gaps = 113/905 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQP 647
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T  +   +T   
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTTGSE--TTTTST 717

Query: 648  AAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNSS 705
                I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +S
Sbjct: 718  EGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------SP 758
            I  G E     T +S+  +E+++ S  S  +  V     +       A ET       S 
Sbjct: 777  IM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 759  TIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP----I 809
            TI      SE+ + TS     T  A  E  +TT      S+    T   S+         
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 810  QMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQPQ 866
            + T       E+ + +   SE+     T +E T   TE +     S          +   
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 867  RTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVE 926
             T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T      
Sbjct: 952  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011

Query: 927  EMDTL 931
            E  T+
Sbjct: 1012 ETTTV 1016



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 164/923 (17%), Positives = 303/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++        +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 110/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437
              +  +  S  T +     K    S +         T  +    S    +         +
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152

Query: 438  SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497
            +     I         +G +  T   + S+      T T  T+ +      ++     T 
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1206

Query: 498  KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557
                + T T  T    T +PS              ++T  S  ++ P + +  G +  + 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTV 1266

Query: 558  NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616
            +I  SG T   TT+  T+    ++ + T      I   P     TT        ++   P
Sbjct: 1267 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1323

Query: 617  TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676
                    +A       IV    G+G++   A+    T   +G +  T    +P   TFQ
Sbjct: 1324 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1378

Query: 677  AT 678
             T
Sbjct: 1379 ET 1380



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/432 (20%), Positives = 153/432 (35%), Gaps = 54/432 (12%)

Query: 501 TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
           TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561 SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
           SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61  SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621 PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
             +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114 TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681 SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
           SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172 SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733 SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
           S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232 SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789 EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
               S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287 STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849 FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                         +    T    +  S+T+T ++   ++  AS+ G+ T       S  
Sbjct: 341 -------SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 909 TAFTKHSEELGT 920
           T  +    E  T
Sbjct: 394 TTVSTTGSETTT 405


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 206/1091 (18%), Positives = 367/1091 (33%), Gaps = 108/1091 (9%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    TA++   AA    +     +  GS+  V  + + TT+  T     + +      
Sbjct: 213  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272

Query: 169  PRPASPAS--NVVVLPSGSTVYVKSVSCSDEDEK----PRKRRRTNSSSSSPVVL---KE 219
               AS           +GS   + S   S+        P   + + +SS    V     E
Sbjct: 273  TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 332

Query: 220  VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ--K 277
              +A    S+T TV  +GS   +  +     S          T +   ++TT  +T+  +
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 278  VIIVTTSPSSTFVPNIL--------SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSS 329
               V+T+ S T   +I         ++     AV+  V  +  AST      + + S S 
Sbjct: 393  ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452

Query: 330  LVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
              + S+ GS ++T +   +         S  +   +T  +  +   I   +T   +  S 
Sbjct: 453  TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512

Query: 390  VSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA----QPSPVSHQQQPQQSPLPPGIK 445
             +A +   ++      +  +             V+    + +  S +     +    G +
Sbjct: 513  TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 446  PTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPT 504
             T    + SG     T   + + +       T  ++++S     S+ G+  TT   T+  
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632

Query: 505  GTQATY-----TRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKS-----LATLGGKI 554
             T A+      T  + + S   M +T G+   + +T GS  T V  +     ++T G   
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692

Query: 555  ISSNIVSGTTTKITTIPM-----TSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
             + +I    TTK++T        +++ + I     TG  TT     G    TT  +  G 
Sbjct: 693  TTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSE--TTTASTEGS 750

Query: 610  KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKI--IPTKIVYGQQGKTQVL 667
            +T     TG++    T T   T    T    +GS    A+ I    TK+       T V 
Sbjct: 751  ETTSASTTGSE----TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF 806

Query: 668  IKPKPVTFQATVVSEQTRQLV--TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTE 725
             +    T  +T  SE T      +ET+  ++  +E   ++  EG E     T+ S ++T 
Sbjct: 807  TENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 726  SSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQT 785
            S++SS+                        T+ T I  + ++ S   + T     E  +T
Sbjct: 867  STESSE-----------------------TTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T      S+    +   S+         E   +    S     S   +E IT   + EG+
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV--SAEGS 961

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
            E                +    T     A S+T T ++   ++  AS  G+ T  +    
Sbjct: 962  ETT-----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 906  SSHTAFTKHSEE---LGTEEGEVEEMDTLDPQTGLFY----RSALTQSQSAKQQKLSQPP 958
            S  T  +    E     TE  E   + T   +T   Y     +  T ++ ++   +S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDV 1018
             E T      L   +T    T             +   + I   K T    E ++     
Sbjct: 1071 SETTTASTADL---ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1019 QHTQHPMVAK--DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQS 1076
              +     A     ++ T+      TV +   V T         A          +  ++
Sbjct: 1128 TTSSETTTASTTGSEMTTVFT----TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSIS 1136
              +  A SE  TAS       T GS  T  +  G +  T       +S P      T+ +
Sbjct: 1184 TTASTAGSETTTAS-------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1236

Query: 1137 PIQASEKTAVS 1147
             I  SE T  S
Sbjct: 1237 FIIGSETTIAS 1247



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 222/1125 (19%), Positives = 385/1125 (34%), Gaps = 107/1125 (9%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRT 207
            ST  + T+TP P+GS  T+ S              SGS +   S + S+          T
Sbjct: 39   STAGSETTTPSPTGSQTTIVSI-------------SGSEITTTSTAGSEN---------T 76

Query: 208  NSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPS 267
              SS+               S T T  ++GS    +   S   ++    +   +     S
Sbjct: 77   TVSSAG--------------SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
              TTN+TT     VT++  S         S    A T    T+  ++T  +   V TA  
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG- 181

Query: 328  SSLVSNSSSGSSSSTPSPI---PNTVAVTAVVSSTPSVVMS--TVAQGVSTSAIKMASTR 382
            S  ++ S++GS ++T S       TV+ T   ++T S   S  T A  + +   K+++  
Sbjct: 182  SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP 442
              +  S   + T   +    +   +  +        T       +  +  +    S +  
Sbjct: 242  SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 443  GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLV-- 500
                   I  E+  K+ T   + + +          ++  S    VS+ G+  TT  +  
Sbjct: 302  ETTMASTIGPET-TKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMG 360

Query: 501  ---TTPTGTQATYTRPTVSPSIGRMAATPGA-ATYVKTTSGSIITVVPKSLATLGGKIIS 556
               +T + T +  T  +   S    A+T G+ AT V TT     TV      T       
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 557  SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE-KTIQTV 615
            S + + +TT   T   +++ + I +  T+   TT     G    TT+  AG E KT  T 
Sbjct: 421  SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSE-TTTVTTAGSETKTAYTT 479

Query: 616  PTGAKPAILTATRPITKMIVTQPKGIGST-------VQPAAKIIPTKIVYGQQGKTQVLI 668
             +    A  T     T   +       ST       V      + T    G +  T    
Sbjct: 480  GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT 539

Query: 669  KPKPVTF---------------QATVVSEQTRQLVTETLQQASRVA--EAGNSSIQEGKE 711
              +  T                + T VS    +  T++ + +   A   AG+ +      
Sbjct: 540  GSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 712  EPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQS 771
            + +N T S++ S  +S S+  S+       S     +  E +  T+ +    + +  S +
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 772  ATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPI---QMTQEKRHSPESPSIAVVE 828
             +       E  +TT      S+    T       V I   + T+      E+   +   
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEG 719

Query: 829  SELVAEYIT-TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV-- 885
            SE+    IT +E T   TE +     S  ++  + +    T  +    S T+++T++   
Sbjct: 720  SEITTASITGSETTTASTEGSETTTAS--TEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 886  --VKSIPASSPGAITHIMQQALSS-HTAFTKHSEE--LGTEEGEVEEMDTLDPQT--GLF 938
               ++  AS+ G+ T  +  A S   T FT++SE     T   E   + T   +T     
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
              S  T + S +  + +    E ++    + +  +T    TI  +      +  +    S
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKL 1058
                + T    E ++             A      T  A    +  ++  V TT      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGS--ELTTVSTTGSETIT 955

Query: 1059 QQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTK 1118
              A       V     ++  +  A SE  T S       T GS  T  + EG +  TV+ 
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVS-------TAGSETTTASIEGSETTTVSS 1008

Query: 1119 ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS 1178
                ++    T   T+I+  + SE T V+     S   A   T  E            T 
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVT--TAGSETTAVYTTGSETTTTSTEGSETTTV 1066

Query: 1179 MLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
              TG   +  ST    A +  +T          ++ ST GS  TT
Sbjct: 1067 STTGSETTTAST----ADLETTTVSTS--GSGTTTASTAGSETTT 1105



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 188/906 (20%), Positives = 324/906 (35%), Gaps = 115/906 (12%)

Query: 109  QTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS 168
            +T    T  +    A   ++     + TGS+    ++  S T TP++    + +++T  S
Sbjct: 143  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRK-----RRRTNSSSSSPVVL-----K 218
                + ++      + ST + ++ + S    +  K        T S++ S          
Sbjct: 203  -ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDS 261

Query: 219  EVPKAVVPVSKTITVPVSG-----------SPKMSNIMQS---IANSLPPHMSPVKITFT 264
            E   A    SKT T   +G            P M++ M S   +A+++ P  + V    +
Sbjct: 262  ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASS 321

Query: 265  KPSTQ--------TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
            + +T           +T   +   V+T+ S T   +I+    +  + T    T+  AST 
Sbjct: 322  EVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT--ASTE 379

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA- 375
                   +   S   + S++GS ++T S   +    T    S  + V +TV +  + S  
Sbjct: 380  GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTE 439

Query: 376  ---IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
               I +AST   S     +A T+           S  +  Y    +T       +  S+ 
Sbjct: 440  GSEITIAST---SDSETTTASTEGSETTTVTTAGSETKTAYTTGSET-------TTASNT 489

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVV-SSN 491
                 +    G   T    + S    +      S    +  T +   S N+ +    S  
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAV------SATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 492  GAIMTTKLVTTPTGTQAT-YTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV------- 543
              + TT L TT T T+ +  T  + + +     +T G+ T   +T+GS  T V       
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 544  ---------PKSLATLGGKIISSNIVSGTTT-------KITTIPMTSKPNVIVVQKTTGK 587
                       S +T G +  +++  S  TT       + TT+  T     +V   TTG 
Sbjct: 604  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV--STTGS 661

Query: 588  GTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTV-Q 646
              TI    G    TT+   G E T+ T  +G     +T +   TK+  T   G  +T+  
Sbjct: 662  ERTITSTEGSE-TTTVSATGSETTVSTEGSGTTTVSITGSE-TTKVSTT---GSETTITS 716

Query: 647  PAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVT--ETLQQASRVAEAGNS 704
                 I T  + G +  T    +    T  +T  SE T    T  ET   ++  +E   +
Sbjct: 717  TEGSEITTASITGSE-TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMA 775

Query: 705  SIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMET-------S 757
            SI  G E     T +S+  +E+++ S  S  +  V     +       A ET       S
Sbjct: 776  SIM-GSET----TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS 830

Query: 758  PTIIYQDVSSESQSATS-----TIKALLELQQTTVKEKLESKPRQPTIDLSQMAVP---- 808
             TI      SE+ + TS     T  A  E  +TT      S+    T   S+        
Sbjct: 831  ETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEG 890

Query: 809  IQMTQEKRHSPESPSIAVVESELVAEYIT-TERTDEGTEVAFPLLVSHRSQ--PQQPSQP 865
             + T       E+ + +   SE+     T +E T   TE +     S          +  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 866  QRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEV 925
              T+      S+T T T++  ++  AS+ G+ T  +  A S  T  +    E  T     
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 926  EEMDTL 931
             E  T+
Sbjct: 1011 SETTTV 1016



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 165/923 (17%), Positives = 304/923 (32%), Gaps = 97/923 (10%)

Query: 313  ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ASTT      I    S   + S++GS ++TPSP   T + T +VS + S + +T   G  
Sbjct: 18   ASTTGSETTTILIKASETTTASTAGSETTTPSP---TGSQTTIVSISGSEITTTSTAGSE 74

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             + +  A +   +     S  T   A                  + T   +         
Sbjct: 75   NTTVSSAGSGTTTASMAGSETTVSTAG----------------SETTTVSITGTETTMVS 118

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
                ++           +   +G +  T     S+        T   +++S     S+ G
Sbjct: 119  AMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-------TTTAYTADSETTAASTTG 171

Query: 493  AIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            + MTT      T    T T P+ + S     +T G+ T   +T+GS  T    + +T   
Sbjct: 172  SEMTTVF----TAGSETIT-PSTAGSETTTVSTAGSETTTVSTTGSETT----TASTAHS 222

Query: 553  KIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTI 612
            +  +++ +   TTK++T    +         T G  TT          T         T 
Sbjct: 223  ETTAASTMGSETTKVSTAGSET------TVSTAGSETTAASTEDSETNTAFTEDSKTTTA 276

Query: 613  QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKP 672
             T       A  T + P     +     + ST+ P      TK+       T V      
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPET----TKVSTASSEVTTVFAAGSE 332

Query: 673  VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
                +TV SE T    T         +E   +SI  G E   + T  S ++T S++ S+ 
Sbjct: 333  TIRASTVGSETTTVSTTG--------SETTTASIM-GSETSTDSTTGSETTTASTEGSET 383

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLE 792
            +        +   + SE      T        ++    + T T  + +    TTV E   
Sbjct: 384  T--------TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 793  SKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI----TTERTDEGTEVA 848
            +      I ++  +   + T       E+ ++    SE    Y     TT  ++ G E  
Sbjct: 436  ASTEGSEITIASTS-DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                +   +        + T +       T   T     +  +++    T +    L + 
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  T+ SE         E   T D   G    S  T + +A  +  +    +       T
Sbjct: 555  TTSTEGSEMTTVSTTGAE--TTTDSTEG----SGTTAASTAGSETTTVSTADSENTTAST 608

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQ-PKPDVQHTQHPMVA 1027
                +T    T   +         +    S    + T +    ++        ++  + +
Sbjct: 609  ADS-ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1028 KD-RQLPTLMAQPPQTVVQVLAVKTT------QQLPKLQQAPNQPKIYVQPQTPQSQMSL 1080
             +  +  T+ A   +T V      TT       +  K+    ++  I     +  +  S+
Sbjct: 668  TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASI 727

Query: 1081 PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQA 1140
               SE  TAS       T+GS  T  + EG +  + +     ++    TS  T+++ I  
Sbjct: 728  -TGSETTTAS-------TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1141 SEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANS 1200
            SE T  S I   +   +   + +  +  +  +  +A++       +   T  V    + +
Sbjct: 780  SETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST-------TASETTTVSTAGSET 832

Query: 1201 TPQQQKCRESCSSPSTVGSSLTT 1223
             P      E+ ++ ST GS  TT
Sbjct: 833  IPASTAGSETTTTTSTEGSETTT 855



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 111/602 (18%), Positives = 205/602 (34%), Gaps = 49/602 (8%)

Query: 103  MPRLVPQTAFTVTANAVAN--AAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS 160
            M  +  + + T  A+  A+    +    S  +PA T   E    + TST  + T+T    
Sbjct: 802  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT--TTTSTEGSETTTASTE 859

Query: 161  GSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVL--- 217
            GS  T  S   +   +   +   GS     S   S+      +   T ++S+    +   
Sbjct: 860  GSETTTASTESSETTTATTI---GSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 218  ----KEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT-FTKPSTQTTN 272
                 E   A    S+T T    GS +++ +  + + ++       + T  T   ++TT 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGS-ELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 273  TTT--QKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSV--------IASTTQKPPVV 322
             +T   +   V+T+ S T   +I        + T    T+V        I ST       
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382
            +T + S   +  ++GS ++T S      + T  VS+T S   +     + T+ +  + + 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTS---TEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 383  LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP-----QQ 437
              +  +  S  T +     K    S +         T  +    S    +         +
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152

Query: 438  SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497
            +     I         +G +  T   + S+      T T  T+ +      ++     T 
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSE------TTTASTAGSETTTASTAGSETTTA 1206

Query: 498  KLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISS 557
                + T T  T    T +PS              +TT  S  ++ P + +  G +  + 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266

Query: 558  NI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVP 616
            +I  SG T   TT+  T+    ++ + T      I   P     TT        ++   P
Sbjct: 1267 SITASGATAASTTVSSTT---FVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAP 1323

Query: 617  TGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQ 676
                    +A       IV    G+G++   A+    T   +G +  T    +P   TFQ
Sbjct: 1324 --GMDFTASAASHTVPGIVLNTSGLGTSTMGASS---TTSAHGVRTTTGSTREPTSSTFQ 1378

Query: 677  AT 678
             T
Sbjct: 1379 ET 1380



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 158/835 (18%), Positives = 268/835 (32%), Gaps = 104/835 (12%)

Query: 501  TTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIV 560
            TT + T +  T   +  S    A+T G+ T   + +GS  T+V                +
Sbjct: 16   TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVS---------------I 60

Query: 561  SGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK 620
            SG  ++ITT       N  V   + G GTT   + G    TT+  AG E T  ++ TG +
Sbjct: 61   SG--SEITTTSTAGSENTTV--SSAGSGTTTASMAGSE--TTVSTAGSETTTVSI-TGTE 113

Query: 621  PAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVV 680
              +++A    T    T      +TV   A    T +       T         T  +T  
Sbjct: 114  TTMVSAMGSETTTNSTTSS--ETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTG 171

Query: 681  SEQTRQLV--TETL------QQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQD 732
            SE T      +ET+       + + V+ AG+ +        +  T S++ S  ++ S+  
Sbjct: 172  SEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMG 231

Query: 733  SQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSA----TSTIKALLELQQTTVK 788
            S+      A      SE  ++   S T       SE+ +A    + T  A     +TT  
Sbjct: 232  SETTKVSTAG-----SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAA 286

Query: 789  EKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVA 848
                S+P   +       +  + T      PE+  ++   SE+   +     T   + V 
Sbjct: 287  STTGSEPTMAS------TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 849  FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                                       S+T T ++   ++  AS  G+ T       S  
Sbjct: 341  ---------------------------SETTTVSTTGSETTTASIMGSETSTDSTTGSET 373

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
            T  +    E  T   E  E  T+   TG     + T + S    + +    E +++   +
Sbjct: 374  TTASTEGSETTTASTEGSEATTVS-TTG-----SETTTVSITDSETTTTCTEGSEMTAVS 427

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAK 1028
               F+T    T   +         +    S    + T +    ++ K           A 
Sbjct: 428  TTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS 487

Query: 1029 DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088
            +  L T       T V  +   TT    +  +         +  T  ++ S   ++   T
Sbjct: 488  NTGLET-------TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS--ENTTVST 538

Query: 1089 ASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVS- 1147
                   + T G   T  + EG +  TV+     ++        T+ +    SE T VS 
Sbjct: 539  TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598

Query: 1148 -DILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQK 1206
             D    +   A  +T            A  TS  T  A +  S    V+   + T     
Sbjct: 599  ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658

Query: 1207 CRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIP 1266
                 +  ST GS  TT       V ATG    +   G          + I       + 
Sbjct: 659  TGSERTITSTEGSETTT-------VSATGSETTVSTEG-----SGTTTVSITGSETTKVS 706

Query: 1267 CHSSSNVVVEPSGL-LELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAE 1320
               S   +    G  +   + T  +     T   +   +STE     S S + +E
Sbjct: 707  TTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSE 761


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 278/1293 (21%), Positives = 449/1293 (34%), Gaps = 168/1293 (12%)

Query: 113  TVTANAVANAAIQHNASLPVPAETG-SKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRP 171
            T +   + +A+  H A   +P  TG +  +V  ++  T S  ++   P+G  ++  SP  
Sbjct: 841  TQSTTELLSASASHGA---IPVSTGMASSIVPGTFHPTLSEASTAGRPTGQ-SSPTSPS- 895

Query: 172  ASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV--PVSK 229
            ASP     +     T   ++   SD      +   T++ S+ P     +    +  P ++
Sbjct: 896  ASPQETAAISRMAQTQRTRTSRGSDTISLASQA--TDTFSTVPPTPPSITSTGLTSPQTE 953

Query: 230  TITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVI---------- 279
            T T+  SGS K      +   +L  + +P+ +T+   S  T +TT   V           
Sbjct: 954  THTLSPSGSGK------TFTTALISNATPLPVTYAS-SASTGHTTPLHVTDASSVSTGHA 1006

Query: 280  --IVTTSPSS------TFVPNILSKSHNYAAVTKLVPTSVI-ASTTQKPPVVITASQSS- 329
              +  TSPSS      T +P   + S +   VT L  TS   AST    P+ +T + S+ 
Sbjct: 1007 TPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSAS 1066

Query: 330  --------LVSNSSSGSSSSTPSPIPNTV-AVTAVVSSTPSVVMSTVAQGVSTSAIKMAS 380
                    + S SS+ +  +TP P+ +T  A T   +S P    S+V+ G  T+ + +  
Sbjct: 1067 TGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTG-HTTPLPVTD 1125

Query: 381  TRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQP-SPVSHQQQPQQSP 439
            T   S     S P    +     H  +P          T Q    P + +S       +P
Sbjct: 1126 TSSASTGHATSLPVTDTSSVSTGHT-TPLHVTDASSASTGQATPLPVTSLSSVSTGDTTP 1184

Query: 440  LPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSSNS----PIMVVSSNGAI 494
            LP     +      + + +  T         P PVT     S++     P+ + S+    
Sbjct: 1185 LPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG 1244

Query: 495  MTTKLVTTPTGT----QATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT---VVPKSL 547
             TT L  T T +    QAT    T + S+     TP   T   + S   +T   V   S 
Sbjct: 1245 HTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSS 1304

Query: 548  ATLGGK--IISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTT--- 602
            A+ G    +  +++ S +T     +P+TS  +      +TG  T +      +V T    
Sbjct: 1305 ASTGHATPLPVTSLSSASTGDTMPLPVTSPSSA-----STGDTTPLPVTDASSVSTGHTT 1359

Query: 603  ---LLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYG 659
               + +A    T Q  P         +T   T + VT P    ++   A  ++ T     
Sbjct: 1360 PLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSS--ASTGHATPLLVTDTSSA 1417

Query: 660  QQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDS 719
              G       P PVT  ++V ++    L       AS            G   P   TD+
Sbjct: 1418 STGHAT----PLPVTDASSVSTDHATSLPVTIPSAAST-----------GHTTPLPVTDT 1462

Query: 720  SSSST----------ESSQSSQDSQPVVHVIASRRQDWSEHEIAME-TSPTIIYQDVSSE 768
            SS+ST           SS S+ D+ P+   + S     + H   +  TSP        S 
Sbjct: 1463 SSASTGQATSLLVTDTSSVSTGDTTPLP--VTSTSSASTGHVTPLHVTSP--------SS 1512

Query: 769  SQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSP--------E 820
            + +  +T   +  L   +  + +      P+   +    P+ +T     S          
Sbjct: 1513 ASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVT 1572

Query: 821  SPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQ--HVAQSQT 878
            SPS A            T    +G     P+     + P   S    T L     + + T
Sbjct: 1573 SPSSASTGHTTPLPVTDTSSASKGDTTPLPV-----TSPSSASTGHTTPLPVTDTSSAST 1627

Query: 879  ATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEEL---GTEEGEVEEMDTLDPQT 935
               T + V +  + S G  T +     S  +A T H+  L    T          L P T
Sbjct: 1628 GDTTPLPVTNASSLSTGHATPL--HVTSPSSASTGHATPLPVTSTSSASTGHATPL-PVT 1684

Query: 936  GLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMP 995
            GL   +    ++       S    + T L V +L    T                LP   
Sbjct: 1685 GLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTP-----------LPVTS 1733

Query: 996  QLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQP-PQTVVQVLAVKTTQQ 1054
              S      +PL    A      Q T  P V     + T  A P P T +   +   T +
Sbjct: 1734 PSSASTGHASPLLVTDASSASTGQATPLP-VTDTSSVSTAHATPLPVTGLSSASTDDTTR 1792

Query: 1055 LPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPI-ITQGSSVTKITFEGRQP 1113
            LP            V   +    + LP +S    ++    P+ +T  SS +  T +    
Sbjct: 1793 LPVTD---------VSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSAS--TGDTTSL 1841

Query: 1114 PTVTKITGGSSVPKLTSPVTSISPIQASEKTA--VSDILKMSLMEAQ----IDTNVEHMI 1167
            P VT  +  SS    + PVT  S +     T+  V+D   +S  +       DTN     
Sbjct: 1842 P-VTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTG 1900

Query: 1168 VDPPKKAL-ATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKI 1226
               P     A+S+ TG A SLP T +  A   ++TP       S SS  T    +T    
Sbjct: 1901 DTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASS 1960

Query: 1227 DPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYA--IPCHSSSNVVVEPSGLLELN 1284
             P     +       +V    A   P          +A  +P   +S+V    +  L + 
Sbjct: 1961 VPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVT 2020

Query: 1285 NFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQS 1317
            + +S    D       D  S++     P P  S
Sbjct: 2021 SLSSASTGDTTPLPVTDTSSASTGQDTPLPVTS 2053



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 262/1263 (20%), Positives = 426/1263 (33%), Gaps = 171/1263 (13%)

Query: 113  TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK----- 167
            T T++A    A   + + P  A TG    +  + TS+ ST  +TP+P  S+++V      
Sbjct: 2916 TDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTT 2975

Query: 168  ---------------SPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSS 212
                           +P P +  S+     + +     + S S  D  P     T+S+S+
Sbjct: 2976 PLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSAST 3035

Query: 213  SPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTN 272
                 +  P  V  +S   T   +  P  S    S  ++ P  ++      T  +T    
Sbjct: 3036 G----QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPV 3091

Query: 273  TTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVS 332
            T+   V    T+P     P+  S  H   A +  V  +  AST     + +T + S+   
Sbjct: 3092 TSLSSVSTGDTTPLPVTSPSSASTGH---ATSLPVTDTSSASTGDTTSLPVTDTSSAYTG 3148

Query: 333  NSSS-----GSSSSTPSPIPNTVAVTAVVS---STPSVVMSTVAQGVST---SAIKMAST 381
            +++S      SSSST    P  V  T+ VS   +TP +V  T A   ST   + + + S 
Sbjct: 3149 DTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLV--TDASSASTGHATPLHVTSP 3206

Query: 382  RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQP-SPVSHQQQPQQSPL 440
               S       P    +     H  +P          T      P + +S     Q +PL
Sbjct: 3207 SSASTGDTTPVPVTDTSSVSTGH-ATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPL 3265

Query: 441  PPGIKPTIQIKQESGVKIIT-QQVQPSKILPKPVTATLPTSSN--SPIMVVSSNGAIM-- 495
            P     ++       + + +          P PVT+T   S+   +P+ V S++ A    
Sbjct: 3266 PVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGH 3325

Query: 496  TTKLVTTPT---GTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGG 552
            TT L  T T    T  T   P  SPS    +A+ G  T +  T       +P S +T   
Sbjct: 3326 TTPLPVTDTSSASTGDTTPLPVTSPS----SASTGHTTPLHVT-------IPSSASTGDT 3374

Query: 553  KIIS-SNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGL-PGKNVVTTLLNAGGEK 610
              +  +   S +T   T +P+T   +V     T    T++  +  G      + +A    
Sbjct: 3375 STLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSAS 3434

Query: 611  TIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKP 670
            T Q  P         +T   T ++VT    +  +   A  +  T       G T  L   
Sbjct: 3435 TGQATPLPVTSLSSVSTGDTTPLLVTDASSV--STGHATPLPVTDTSSASTGDTTRL--- 3489

Query: 671  KPVTFQATVVSEQTRQLVTETLQQASR-----VAEAGNSSIQEGKEEPQNYTDSSSSST- 724
             PVT  ++  + Q   L   +L   S      +     SS+  G   P   TD+SS+ST 
Sbjct: 3490 -PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTG 3548

Query: 725  ---------ESSQSSQDSQPVVHVIASRRQDWSEHEIAME---------------TSPT- 759
                      SS S+  + P+   I S         + +                TSP+ 
Sbjct: 3549 DTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSS 3608

Query: 760  -----IIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMA------VP 808
                 +    V+S S ++T     LL    ++V     +    P  D S  +      +P
Sbjct: 3609 ASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATP--LPVTDASSASTGDTTPLP 3666

Query: 809  IQMTQEKRHSPESP----SIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQ 864
            +  T        +P    S++ V +        T+ +   T  A PL V   + P   S 
Sbjct: 3667 VTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPV---TIPSSVST 3723

Query: 865  PQRTLLQHVAQSQTAT--QTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEE 922
                 L   + S  +T   T + V  + ++S G  T +     SS  A T+H+  L    
Sbjct: 3724 GDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSS--ASTRHATPLPV-- 3779

Query: 923  GEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQL----QVKTLQCFQTKQKQ 978
                  DT    T    R  +T   SA     +  P+  T          L    T    
Sbjct: 3780 -----TDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVS 3834

Query: 979  TIHLQADQLQHK----------LPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAK 1028
            T H  +  +  +          LP     S+     TPL             T  P+ + 
Sbjct: 3835 TGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSP 3894

Query: 1029 DRQLPTLMAQPPQTVVQVLAVKTTQQLP-----KLQQAPNQPKIYVQPQTPQ----SQMS 1079
                       P T     +   T  LP      L      P     P +      S + 
Sbjct: 3895 SSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLP 3954

Query: 1080 LPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQ 1139
            +  +S   T      P+    +S++ ++     P  VT  +  S+      PVTS+S + 
Sbjct: 3955 VTDASSASTGHATPLPL----TSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVS 4010

Query: 1140 ASEKTAVSDILKMSLMEAQID-------TNVEHMIVDPPKKALATSMLTGEAGSLPSTHM 1192
              + T +   +  S              ++V      P      +S  TG+   LP T  
Sbjct: 4011 TGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDT 4070

Query: 1193 VVAGMANSTPQQQKCRESCSS------PSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQK 1246
              A   ++TP       S S+      P T  SS++T    P AV +      + +    
Sbjct: 4071 SSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDSPL 4130

Query: 1247 KAE 1249
            K E
Sbjct: 4131 KME 4133



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 275/1225 (22%), Positives = 423/1225 (34%), Gaps = 221/1225 (18%)

Query: 113  TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS---- 168
            T T++A    A     + P  A TG    +  + TS+ ST  +TP+P  S+++  +    
Sbjct: 2196 TDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTT 2255

Query: 169  PRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSS------------SSPVV 216
            P P + AS+V    + S       S S  D  P      +S+S            SS   
Sbjct: 2256 PLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSAST 2315

Query: 217  LKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS-----------PVKIT--- 262
                P  V  +S   T   +  P  S    S  ++ P H++           P+ +T   
Sbjct: 2316 GHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSS 2375

Query: 263  -----------FTKPSTQTTNTTTQKVIIVTTSPSS---TFVPNILSKSHNYAAVTKLVP 308
                        T  S+ +T  TT   +  T+S S+   T +P     S +    T+L  
Sbjct: 2376 SASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPV 2435

Query: 309  TSVI-ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVM--S 365
            T+V  AST    P+ +T       S SS+ +  +TP P  +T +V+    +TP +V   S
Sbjct: 2436 TNVSSASTGHATPLPVT-------STSSASTGDTTPLPGTDTSSVSTG-HTTPLLVTDAS 2487

Query: 366  TVAQGVST----SAIKMASTRLPSPKSLVSAP---TQILAQFPKQHQQSPKQQLYQVQQQ 418
            +V+ G +T    ++   AST   +P  +   P   T      P  +  S        +  
Sbjct: 2488 SVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASS-----LSTRHA 2542

Query: 419  TQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPVTATL 477
            T   V  PS  S       + LP            + + +  T         P PVT T 
Sbjct: 2543 TSLHVTSPSSAS---TGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTY 2599

Query: 478  PTSSNS----PIMVVSSNGAIMTTKLVTTPTGTQAT-YTRP---TVSPSIGRMAATPGAA 529
              S+      P+   SS     TT L  T T + +T +  P   T + S+    ATP   
Sbjct: 2600 SASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHV 2659

Query: 530  TYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGT 589
            T   + S    T +P + A+           S +T   T++P+T   +V      TG  T
Sbjct: 2660 TSPSSASTGHTTPLPVTDAS-----------SVSTGHATSLPVTDASSVF-----TGHAT 2703

Query: 590  TIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAA 649
            ++        VT   +A       T P     A   +T   T + VT    + +      
Sbjct: 2704 SLP-------VTIPSSASSG---HTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPL 2753

Query: 650  KIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL-VTETLQ----QASRVAEAGNS 704
             +     V            P P+T  ++V +  T  L VT+T      QA+ +     S
Sbjct: 2754 PVTDASSVSTGHAT------PLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLS 2807

Query: 705  SIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQD 764
            S+  G   P   TD+SS+ST        S PV    ++     + H   +  + T     
Sbjct: 2808 SVSTGDTTPLPVTDTSSAST----GHATSLPVTDTSSAS----TGHATPLPDTDT----- 2854

Query: 765  VSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQM----AVPIQMTQEKRHSPE 820
                  S+ ST  A L     T    +      P  D S +    A P+ +T     SP 
Sbjct: 2855 ------SSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVT-----SPS 2903

Query: 821  SPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLL--QHVAQSQT 878
            S S        V     T+ +   T  A PL   H + P   S    T L     + + T
Sbjct: 2904 SASTGHATPLPV-----TDTSSASTGHANPL---HVTSPSSASTGHATPLPVTDTSSAST 2955

Query: 879  ATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLF 938
               T + V S+ + S G  T +     S  +A T H+  L          DT    TG  
Sbjct: 2956 GHATPLPVTSLSSVSTGDTTPL--PVTSPSSASTGHTTPLPV-------TDTSSASTGQA 3006

Query: 939  YRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLS 998
                +T + SA          + T L V       T Q              LP     S
Sbjct: 3007 TALPVTSTSSASTG-------DTTPLPVTDTSSASTGQAT-----------PLPVTSLSS 3048

Query: 999  IRHQKLTPLQQEQAQPKPDVQHTQH--PMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLP 1056
            +     TPL        P    T H  P++  D    +     P  V  + +V T    P
Sbjct: 3049 VSTGDTTPL----PVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTP 3104

Query: 1057 KLQQAPNQ---------PKIYVQPQTPQSQMSLPA--SSEKQTASQVEQPIITQGSSVTK 1105
                +P+          P       +     SLP   +S   T      P+    SS T 
Sbjct: 3105 LPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTG 3164

Query: 1106 ITFEGRQPPTVTK---ITGGSSVPKLTSPVTSIS-----PIQASEKTAVS--DILKMSLM 1155
             T     P  VT+   ++ G + P L +  +S S     P+  +  ++ S  D   + + 
Sbjct: 3165 DT----TPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVT 3220

Query: 1156 EAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSS-- 1213
            +    ++V      P      +S  TG+   LP T +  A    +TP       S S+  
Sbjct: 3221 DT---SSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGD 3277

Query: 1214 ----PSTVGSSLTTRKIDPPAVPAT 1234
                P T  SS +T    P  V +T
Sbjct: 3278 TMPLPVTSPSSASTGHATPLPVTST 3302



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 265/1355 (19%), Positives = 456/1355 (33%), Gaps = 165/1355 (12%)

Query: 47   DLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRL 106
            ++ G +S+  S S E   + +    N   +T+    ++    S+  +      VP+   L
Sbjct: 230  NVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSL 289

Query: 107  VPQTAFTVTA--------NAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPV 158
            +P T+  +             +  + Q   +     +T S E    S  +T +T   TPV
Sbjct: 290  MPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNT--LTPV 347

Query: 159  PSGSIATVKSPRPASPASNVV--VLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVV 216
             + ++  + SP   +P+  V     PSG T      S S+      K  R  +S  S   
Sbjct: 348  TTSTV--LSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDS--T 403

Query: 217  LKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA-------NSLPPHMSPVKITFTKPSTQ 269
            L    +  + VS TI+   S   K+S I  S         +SLPP +S    T      +
Sbjct: 404  LGNTEETSLSVSGTISAITS---KVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAE 460

Query: 270  TTNTTTQKVI--------IVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPV 321
            TT    ++          I T   ++T+  +  SK H   + T+L  TS  A+T      
Sbjct: 461  TTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRL---- 516

Query: 322  VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTA------VVSSTPSVVMSTVAQGVSTSA 375
                    +  N S+G++ + P  +P+ V+           SS  + +  T   G  T  
Sbjct: 517  --------VTGNPSTGTAGTIPR-VPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQW 567

Query: 376  IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQ-- 433
             +   T   + ++L+S+P+  + Q  K         +  + + T QQ+      +H    
Sbjct: 568  TQETGT---TGEALLSSPSYSVTQMIKTATSPSSSPM--LDRHTSQQITTAPSTNHSTIH 622

Query: 434  ----QPQQSPLPP--GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMV 487
                 PQ+SP     G     Q  QES        +  +K +  P  ++   S +SP  +
Sbjct: 623  STSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTP-GSSFTASGHSPSEI 681

Query: 488  VSSNGAIMT--TKLVTTPTG----TQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541
            V  +   ++  T     PTG    TQA  T    +PS       P   T +  T    +T
Sbjct: 682  VPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGA--LT 739

Query: 542  VVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT 601
            +    ++T GG        S +T+  T   MT        + T   G T    P  +   
Sbjct: 740  LANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQA---ESTEASGQTQTSEPASSGSR 796

Query: 602  TLLNAGGEKTIQTVPTGAKPAILT--ATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYG 659
            T  +AG      +  +G  P+     +T   T    + P     T Q   +++     +G
Sbjct: 797  TT-SAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHG 855

Query: 660  Q-QGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTD 718
                 T +     P TF  T+                   +EA  +    G+  P   T 
Sbjct: 856  AIPVSTGMASSIVPGTFHPTL-------------------SEASTAGRPTGQSSP---TS 893

Query: 719  SSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKA 778
             S+S  E++  S+ +Q       SR  D     I++ +  T  +  V     S TST   
Sbjct: 894  PSASPQETAAISRMAQ-TQRTRTSRGSD----TISLASQATDTFSTVPPTPPSITSTGLT 948

Query: 779  LLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYIT- 837
              + +  T+      K     +  +   +P+           +P      S +   + T 
Sbjct: 949  SPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATP 1008

Query: 838  ---TERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSP 894
               T  +   T    PL V+  S  +         +   + + T   T + V    ++S 
Sbjct: 1009 LPVTSPSSVSTGHTTPLPVTDTSS-ESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSAST 1067

Query: 895  GAITHIMQQALSSHTA-------FTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQ 947
            G +T +   +LSS +         T  S         +   DT    TG      +T + 
Sbjct: 1068 GHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTS 1127

Query: 948  SAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPL 1007
            SA     +  P+  T   V T                 Q    LP     S+     TPL
Sbjct: 1128 SASTGHATSLPVTDTS-SVSTGHTTPLHVTDASSASTGQAT-PLPVTSLSSVSTGDTTPL 1185

Query: 1008 QQEQAQPKPDVQHTQH--PMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQP 1065
                    P    T H  P++  D    +     P  V    +V T          P+  
Sbjct: 1186 PVTS----PSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAA 1241

Query: 1066 KIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSV------TKITFEGRQPPT-VTK 1118
                    P +  S  ++ +  +    +   ++ G +       T     G   P  VT 
Sbjct: 1242 STGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTS 1301

Query: 1119 ITGGSSVPKLTSPVTSIS----------PIQASEKTAVSDILKMSLMEAQIDTNVEHMIV 1168
             +  S+      PVTS+S          P+ +    +  D   + + +A   ++V     
Sbjct: 1302 PSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDA---SSVSTGHT 1358

Query: 1169 DPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSS-LTTRKID 1227
             P     A+S  TG+A  LP T +      ++TP         +SPS+  +   T   + 
Sbjct: 1359 TPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPL------PVTSPSSASTGHATPLLVT 1412

Query: 1228 PPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFT 1287
              +  +TG    +            A  +   IP  A   H++          L + + +
Sbjct: 1413 DTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTP---------LPVTDTS 1463

Query: 1288 SQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS 1322
            S       + +  D  S +   T P P  S++  S
Sbjct: 1464 SASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAS 1498



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 263/1232 (21%), Positives = 427/1232 (34%), Gaps = 165/1232 (13%)

Query: 111  AFTVTANAVANAAIQHNASLPVP----AETGSKEVVCYSYTSTTSTPTSTPVPSGSIATV 166
            A ++     ++ +  H   LPV       TG    +  + TS+ ST  +TP+P  S+++ 
Sbjct: 1966 ATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSA 2025

Query: 167  K----SPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSS---SSPVVLKE 219
                 +P P +  S+               S S  D  P      +S+S   ++P+++ +
Sbjct: 2026 STGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTD 2085

Query: 220  VPKAVVPVSKTITVPVSGSPKMSN---IMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQ 276
                    + ++ V  + S    +   +  + A+SL        +  T PS+ +T  TT 
Sbjct: 2086 ASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTG-DTTPLPVTSPSSASTGDTTP 2144

Query: 277  KVIIVTTSPS-----STFVPNILSKSHNYAAVTKLVPTSVI---------------ASTT 316
              +  T+S S     S  V +  S S  +A    +  TS                 AST 
Sbjct: 2145 LPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTG 2204

Query: 317  QKPPVVITASQSS--------LVSNSSSGSS-SSTPSPIPN-TVAVTAVVSSTPSVVMST 366
            Q  P+ +T+  S+        LV+++SS S+  +TP P+ + + A T   +  P    S+
Sbjct: 2205 QATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASS 2264

Query: 367  VAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQ-VAQ 425
            V+ G +TS   +  T L S  +  + P  + +  P          L+     +     A 
Sbjct: 2265 VSTGHATS---LPVTSLSSVSTGDTTPLPVTS--PSSASTGHATPLHVTDASSASTGHAT 2319

Query: 426  PSPV---SHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPVTATLPTSS 481
            P PV   S       +PLP     +      + + +     V      P PVT++   SS
Sbjct: 2320 PLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASS 2379

Query: 482  NS----PIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSG 537
                  P+   SS     TT L  T T + +T    T  P  G  +A+ G  T +  T+ 
Sbjct: 2380 GHTTPLPVTDASSASTGDTTPLPVTDTSSAST-GHATHLPVTGLSSASTGDTTRLPVTNV 2438

Query: 538  SI--------ITVVPKSLATLGGKI-ISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKG 588
            S         + V   S A+ G    +     S  +T  TT  + +  + +    TT   
Sbjct: 2439 SSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLP 2498

Query: 589  TTIQGLPGKNVVTTL--LNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQ 646
             T          T L   +     T  T P     A   +TR  T + VT P    +   
Sbjct: 2499 VTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHA 2558

Query: 647  PAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL-VTETLQ----QASRVAEA 701
             +  +  T               P PVT  ++  +  T  L VT+T      QA+ +   
Sbjct: 2559 TSLPVTDTSAASTGHA------TPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVT 2612

Query: 702  GNSSIQEGKEEPQNYTDSSSSST----------ESSQSSQDSQPVVHVIASRRQDWSEHE 751
              SS   G   P   TD+SS+ST           SS S+  + P +HV +          
Sbjct: 2613 DTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATP-LHVTSPSSASTG--- 2668

Query: 752  IAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQM 811
                T+P  +    S  +  ATS    + +                P+   S    P+ +
Sbjct: 2669 ---HTTPLPVTDASSVSTGHATSL--PVTDASSVFTGHATSLPVTIPSSASSGHTTPLPV 2723

Query: 812  TQEKRHSP-ESPSIAVVESELVA-----EYITTERTDEGTEVAFPL-LVSHRSQPQQPSQ 864
            T     S   + S+ V ++  V+         T+ +   T  A PL L S  S     + 
Sbjct: 2724 TDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTT 2783

Query: 865  PQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGE 924
            P    +   + + T   T + V S+ + S G  T +     SS  A T H+  L   +  
Sbjct: 2784 P--LPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSS--ASTGHATSLPVTDTS 2839

Query: 925  ---------VEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTK 975
                     + + DT    TG      +T + SA            T L V       T 
Sbjct: 2840 SASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIG-------HATSLPVTDTSSISTG 2892

Query: 976  QKQTIHLQADQLQH-----KLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQH--PMVAK 1028
                +H+ +           LP     S       PL        P    T H  P+   
Sbjct: 2893 HATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLH----VTSPSSASTGHATPLPVT 2948

Query: 1029 DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088
            D    +     P  V  + +V T    P    +P+         TP   + +  +S   T
Sbjct: 2949 DTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSAS--TGHTTP---LPVTDTSSAST 3003

Query: 1089 ASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSD 1148
                  P+ +  S+ T  T     P  VT  +  S+      PVTS+S +   + T +  
Sbjct: 3004 GQATALPVTSTSSASTGDT----TPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLP- 3058

Query: 1149 ILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCR 1208
                S   A        ++ D      A+S  TG+A  LP T +      ++TP      
Sbjct: 3059 --VTSPSSASTGHATPLLVTD------ASSASTGQATPLPVTSLSSVSTGDTTPLPVTSP 3110

Query: 1209 ESCSS------PSTVGSSLTTRKIDPPAVPAT 1234
             S S+      P T  SS +T   D  ++P T
Sbjct: 3111 SSASTGHATSLPVTDTSSASTG--DTTSLPVT 3140



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 266/1261 (21%), Positives = 429/1261 (34%), Gaps = 207/1261 (16%)

Query: 126  HNASLPVP----AETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKS----PRPASPASN 177
            H  SLPV     A +G    +  +  S+ ST  +T +P    ++V +    P P + AS+
Sbjct: 2701 HATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASS 2760

Query: 178  VVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVV-LKEVPKAVVPVSKTITVPVS 236
            V    +         S S  D  P     T+S+S+     L     + V    T  +PV+
Sbjct: 2761 VSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVT 2820

Query: 237  GSPKMSNIMQSIANSLPP---------HMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSS 287
             +   S      A SLP          H +P+      P T T++ +T    ++  + +S
Sbjct: 2821 DTSSAST---GHATSLPVTDTSSASTGHATPL------PDTDTSSASTGHATLLPVTDTS 2871

Query: 288  TFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIP 347
                   S S  +A    +  TS I ST    P+ +T       S SS+ +  +TP P+ 
Sbjct: 2872 -------SASIGHATSLPVTDTSSI-STGHATPLHVT-------SPSSASTGHATPLPVT 2916

Query: 348  NTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQS 407
            +T + +   ++   V   + A     + + +  T   S       P   L+         
Sbjct: 2917 DTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSV------- 2969

Query: 408  PKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPS 466
                       T   V  PS  S       +PLP     +    Q + + +  T      
Sbjct: 2970 ------STGDTTPLPVTSPSSAS---TGHTTPLPVTDTSSASTGQATALPVTSTSSASTG 3020

Query: 467  KILPKPVTATLPTSSNS----PIMVVSSNGAIMTTKL-VTTPTGTQATYTRP---TVSPS 518
               P PVT T   S+      P+  +SS     TT L VT+P+     +  P   T + S
Sbjct: 3021 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASS 3080

Query: 519  IGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNV 578
                 ATP   T + + S    T +P +  +      ++++    T+  +T   TS P  
Sbjct: 3081 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVT 3140

Query: 579  IVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKT------IQTVPTG-AKPAILT-----A 626
                  TG  T++       V  T  ++ G+ T        +V TG A P ++T     +
Sbjct: 3141 DTSSAYTGDTTSLP------VTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSAS 3194

Query: 627  TRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVT-FQATVVSEQTR 685
            T   T + VT P    +       +  T  V            P PVT   +    + TR
Sbjct: 3195 TGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHAT------PLPVTGLSSASTGDTTR 3248

Query: 686  QLVTE----TLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST----------ESSQSSQ 731
              VT+    +  QA+ +     SS+  G   P   T  SS+ST           SS S+ 
Sbjct: 3249 LPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTG 3308

Query: 732  DSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKL 791
             + PV   + S     + H     T+P  +  D SS S   T+ +        +T     
Sbjct: 3309 HATPVP--VTSTSSASTGH-----TTPLPV-TDTSSASTGDTTPLPVTSPSSASTG---- 3356

Query: 792  ESKPRQPTI-------DLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEG 844
             + P   TI       D S + V    +    H+   P               T+ +   
Sbjct: 3357 HTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLP--------------VTDTSSVS 3402

Query: 845  TEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQA 904
            T  A PL V+  S           +    + + T   T + V S+ + S G  T ++   
Sbjct: 3403 TGHATPLPVTSLSSVSTGDTTPLPVTD-ASSASTGQATPLPVTSLSSVSTGDTTPLLVTD 3461

Query: 905  LSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQL 964
             SS +  T H+  L          DT    TG   R  +T + SA          + T L
Sbjct: 3462 ASSVS--TGHATPLPVT-------DTSSASTGDTTRLPVTDTSSASTG-------QATPL 3505

Query: 965  QVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHP 1024
             V +L    T          D     +     +S  H    P+    +    D   T+ P
Sbjct: 3506 PVTSLSSVST---------GDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDT--TRLP 3554

Query: 1025 MVAKDRQLPTLMAQP-PQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPAS 1083
             V       T  A P P T+    +   T  LP      +   +     TP   + + + 
Sbjct: 3555 -VTDTSSASTGQATPLPVTIPSSSSSGHTTPLP----VTSTSSVSTGHVTP---LHVTSP 3606

Query: 1084 SEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEK 1143
            S   T      P+ +  S+ T        P  VT  +  S+      PVT  S     + 
Sbjct: 3607 SSASTGHVTPLPVTSTSSASTGHA----TPLLVTDASSVSTGHATPLPVTDASSASTGDT 3662

Query: 1144 TA--VSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANST 1201
            T   V+D    S  +A            P      +S+ TG+   LP T    A   ++T
Sbjct: 3663 TPLPVTDTSSASTGQAT-----------PLPVTSLSSVSTGDTTPLPVTDASSASTGHAT 3711

Query: 1202 PQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIP 1261
            P       S S+  T+   +T+     P+  +TG    +   G   A             
Sbjct: 3712 PLPVTIPSSVSTGDTMPLPVTS-----PSSASTGHATPLPVTGLSSASTGDTT------- 3759

Query: 1262 QYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAER 1321
               +P   +S+     +  L + + +S   DD       D+ S++     P P  S++  
Sbjct: 3760 --PLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSA 3817

Query: 1322 S 1322
            S
Sbjct: 3818 S 3818



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 136/554 (24%), Positives = 213/554 (38%), Gaps = 73/554 (13%)

Query: 126  HNASLPVP----AETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVK----SPRP---ASP 174
            H   LPV     A TG    +  + TS+ ST  +TP+P  S+++V     +P P   AS 
Sbjct: 3645 HATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASS 3704

Query: 175  ASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVP 234
            AS     P   T+   SVS  D    P       +S SS       P  V  +S   T  
Sbjct: 3705 ASTGHATPLPVTI-PSSVSTGDTMPLP------VTSPSSASTGHATPLPVTGLSSASTGD 3757

Query: 235  VSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNIL 294
             +  P     +   +++   H +P+ +T T  S+ +T+ TT+  +   +S S+     + 
Sbjct: 3758 TTPLP-----VTDTSSASTRHATPLPVTDT--SSASTDDTTRLPVTDVSSASTGHATPLP 3810

Query: 295  SKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSL--VSNSSSGSSSSTPSPIPNTVAV 352
              S + A+     P  V  +++     V T   +SL   S SS+ +  +TP P+ +T +V
Sbjct: 3811 VTSTSSASTGDTTPLPVTDTSS-----VSTGHATSLPVTSRSSASTGHATPLPVTDTSSV 3865

Query: 353  -TAVVSSTPSVVMSTVAQGVST----SAIKMASTRLPSP---KSLVSAPTQILAQFPKQH 404
             T   +  P    S+V+ G +T    ++   AST   +P    S  SA T      P  +
Sbjct: 3866 STGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTN 3925

Query: 405  QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIIT-QQV 463
              S           T   V  PS  S   +   S LP     +      + + + +   V
Sbjct: 3926 ASS-----LSTGHATPLHVTSPSSAS---RGDTSTLPVTDASSASTGHATPLPLTSLSSV 3977

Query: 464  QPSKILPKPVTATLPTSSNS----PIMVVSSNGAIMTTKL-VTTPTGTQATYTRP---TV 515
                  P PVT T   S+      P+  +SS     TT L VT P+   + +T     T 
Sbjct: 3978 STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTD 4037

Query: 516  SPSIGRMAATPGAATYVKTTSGSIITVVP---KSLATLG--GKIISSNIVSGTTTKITTI 570
            + S+     TP   T   + S    T +P    S A+ G    +  ++  S +T   T +
Sbjct: 4038 ASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPL 4097

Query: 571  PMTSKPNV-------IVVQKTTGKGTTIQGLPGK----NVVTTLLNAGGEKTIQTVPTGA 619
            P+TS  +V       + V   T   T     P K     + T  L   G +   T P   
Sbjct: 4098 PVTSLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPT 4157

Query: 620  KPAILTATRPITKM 633
                + +T P T M
Sbjct: 4158 TSQTIISTIPSTAM 4171



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 159/703 (22%), Positives = 263/703 (37%), Gaps = 122/703 (17%)

Query: 110  TAFTVTANAVANAAIQHNASLPVP----AETGSKEVVCYSYTSTTSTPTSTPVPSGSIAT 165
            T+  VT  + A+    H   LPV     A TG    +  + TS+ ST  +TP+P  S ++
Sbjct: 1231 TSLPVTIPSAASTG--HTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSS 1288

Query: 166  ----------VKSPRPAS-------PASNVVVLPSGSTV---YVKSVSCSDEDEKPRKRR 205
                      V SP  AS       P +++    +G T+        S S  D  P    
Sbjct: 1289 ASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVT 1348

Query: 206  RTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265
              +S S+        P  V   S   T   +  P  S    S  ++ P       +  T 
Sbjct: 1349 DASSVSTGHTT----PLHVTDASSASTGQATPLPVTSLSSVSTGDTTP-------LPVTS 1397

Query: 266  PSTQTTNTTTQKVIIVTTSPSSTF-----VPNILSKSHNYA-AVTKLVPTSVIASTTQKP 319
            PS+ +T   T  ++  T+S S+       V +  S S ++A ++   +P++     T   
Sbjct: 1398 PSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPL 1457

Query: 320  PVVITASQSS------LVSNSSSGSSS-STPSPIPNTVA-----VTAVVSSTPSVVMSTV 367
            PV  T+S S+      LV+++SS S+  +TP P+ +T +     VT +  ++PS   +  
Sbjct: 1458 PVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGH 1517

Query: 368  AQGVSTSAIKMASTR------LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421
            A  +  +++  AST       + SP S  +  T  L         +       V   +  
Sbjct: 1518 ATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSA 1577

Query: 422  QVAQPSPV-----SHQQQPQQSPLPPGIKPTIQIKQESGVKII-TQQVQPSKILPKPVT- 474
                 +P+     S   +   +PLP     +      + + +  T         P PVT 
Sbjct: 1578 STGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTN 1637

Query: 475  -ATLPTSSNSPIMVVSSNGA-------IMTTKLVTTPTG----------TQATYTRPTVS 516
             ++L T   +P+ V S + A       +  T   +  TG          + AT    T  
Sbjct: 1638 ASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRL 1697

Query: 517  PSIGRMAATPGAATYVKTTSGSIIT--------VVPKSLATLG--GKIISSNIVSGTTTK 566
            P     +A+ G AT +  TS S ++        V   S A+ G    ++ ++  S +T +
Sbjct: 1698 PVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQ 1757

Query: 567  ITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTA 626
             T +P+T   +V     T         LP    VT L +A  + T +   T    A    
Sbjct: 1758 ATPLPVTDTSSVSTAHATP--------LP----VTGLSSASTDDTTRLPVTDVSSASTGQ 1805

Query: 627  TRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQ 686
              P+    VT P    ++      +  T       G T  L    PVT  ++  S  T  
Sbjct: 1806 AIPLP---VTSPSS--ASTGDTTPLPVTDASSASTGDTTSL----PVTIPSSASSGHTTS 1856

Query: 687  L-VTETLQ----QASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724
            L VT+        A+ +     SS+  G   P   TD++S+ST
Sbjct: 1857 LPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSAST 1899



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 264/1338 (19%), Positives = 450/1338 (33%), Gaps = 188/1338 (14%)

Query: 56   LSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVT 115
            +S S++ H+ +     +  +  T+   M+    SS  S+       +M    P    T  
Sbjct: 70   ISASSQNHQTKSTETTSKAQTDTLTQMMTSTLFSSP-SVHN-----VMETAPPDEMTTSF 123

Query: 116  ANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPA 175
             ++V N  +  + ++ +   T S  +     TST  T +STPV S    T      +   
Sbjct: 124  PSSVTNTLMMTSKTITMTTSTDST-LGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTT 182

Query: 176  SNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPV 235
            S            ++  S S ++   R  + T  S +S                T+T   
Sbjct: 183  S--------WRTSIQDTSASSQNHWTRSTQTTRESQTS----------------TLTHRT 218

Query: 236  SGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTT--TQKVIIVTTSPSSTFVPNI 293
            + +P  S  + ++  ++    SP   T T      TNT+  T + I VTTS  ST     
Sbjct: 219  TSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTL--GN 276

Query: 294  LSKSHNYAAVTKLVPTSVIASTTQKP--PVVITASQSSLVSNSSSGSSSSTPSPIPNTVA 351
              ++ +      L+P +  A  T  P      T S++S    ++   +  T S     V+
Sbjct: 277  PGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVS 336

Query: 352  VTAVVSSTPSVVMSTVAQGVS--TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPK 409
                +++   V  STV    S    +  ++    PS ++  S+P+ +   F         
Sbjct: 337  QINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTF--------- 387

Query: 410  QQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKIL 469
                   +  +   ++ S + + ++   S        T ++        ++  + PS + 
Sbjct: 388  ---LVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLP 444

Query: 470  PKPVTATLPTSSNSPIMVVSSNGAIMT----TKLVTTPTGTQATYT--RPTVSPSIGRMA 523
            PK  TA              S GA  T     +   +P  +Q  +T    T  PS     
Sbjct: 445  PKISTA---------FHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPS---SF 492

Query: 524  ATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTI-----PMTSKPNV 578
            ++ G  T+ +T   S  T     L T      ++  +    +K++ I     P T   + 
Sbjct: 493  SSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHS 552

Query: 579  IVVQKTTGKGTTIQGLPGKNVV-TTLLNAGGEKTIQTVPTGAKPAIL-TATRPITKMIVT 636
              + KTTG G   Q           LL++      Q + T   P+      R  ++ I T
Sbjct: 553  TTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITT 612

Query: 637  QPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQAS 696
             P    ST+   +          Q+G TQ          Q T  S+ TR +    +    
Sbjct: 613  APSTNHSTIHSTSTSPQESPAVSQRGHTQAP--------QTTQESQTTRSV--SPMTDTK 662

Query: 697  RVAEAGNSSIQEGKEE----PQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEI 752
             V   G+S    G       PQ+    S+++T +   + D         + +   S H+ 
Sbjct: 663  TVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDA 722

Query: 753  AMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMT 812
             +  S           S S T  +         T+   + S P  P     Q       T
Sbjct: 723  TLGPS--------GGTSLSKTGAL---------TLANSVVSTPGGPE---GQWTSASAST 762

Query: 813  QEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQH 872
                 +  + +     +E   +  T+E    G+        +  S     + P  +  + 
Sbjct: 763  SPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGS--EG 820

Query: 873  VAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKH-----------SEELGTE 921
            ++ S   T+ S        S+P   +H  Q      +A   H           S   GT 
Sbjct: 821  ISTSGETTRFS--------SNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTF 872

Query: 922  EGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIH 981
               + E  T    TG   +S+ T   ++ Q+  +   + QTQ + +T     ++   TI 
Sbjct: 873  HPTLSEASTAGRPTG---QSSPTSPSASPQETAAISRMAQTQ-RTRT-----SRGSDTIS 923

Query: 982  L--QADQLQHKLPQMPQLSIRHQKLTPLQQE--QAQPKPDVQHTQHPMVAKDRQLPTLMA 1037
            L  QA      +P  P  SI    LT  Q E     P    +     +++    LP   A
Sbjct: 924  LASQATDTFSTVPPTPP-SITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYA 982

Query: 1038 QPPQT-------VVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTAS 1090
                T       V    +V T    P    +P+   +     TP   + +  +S + T  
Sbjct: 983  SSASTGHTTPLHVTDASSVSTGHATPLPVTSPS--SVSTGHTTP---LPVTDTSSESTGH 1037

Query: 1091 QVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTS-PVTSISPIQASEKT--AVS 1147
                P+ +  S+ T     G   P     T  +S   +T  PVTS+S     + T   V+
Sbjct: 1038 VTPLPVTSFSSAST-----GDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVT 1092

Query: 1148 DILKMSLMEAQ----IDT-NVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTP 1202
            D    S   A      DT +V      P      +S  TG A SLP T        ++TP
Sbjct: 1093 DTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTP 1152

Query: 1203 QQQKCRESCSS------PSTVGSSLTTRKIDP-----PAVPATGQFMRIQNVGQKKAEES 1251
                   S S+      P T  SS++T    P     P+  +TG    +       A   
Sbjct: 1153 LHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTG 1212

Query: 1252 PAEIIIQAIPQYAIPCHSSSNVVVEPSGL-------LELNNFTSQQLDDEETAMEQDIDS 1304
             A  +           H++S  V  PS         L + + +S       + +  D  S
Sbjct: 1213 HATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSS 1272

Query: 1305 STEDGTEPSPSQSSAERS 1322
             +   T P P  S++  S
Sbjct: 1273 VSTGDTTPLPVTSTSSAS 1290



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 75/308 (24%), Positives = 125/308 (40%), Gaps = 36/308 (11%)

Query: 113  TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVP---SGSIAT---- 165
            T T++     A     + P  A TG    V  + TS+ ST  +TP+P   + S++T    
Sbjct: 3876 TSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHAT 3935

Query: 166  ---VKSPRPASPASN----VVVLPSGSTVYVKSV------SCSDEDEKPRKRRRTNSSS- 211
               V SP  AS        V    S ST +   +      S S  D  P     T+S+S 
Sbjct: 3936 PLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSAST 3995

Query: 212  --SSPVVLKEVPKA----VVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTK 265
              ++P+ +  +         P+  TI    S     S  +   ++    H +P+ +T T 
Sbjct: 3996 GQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTST- 4054

Query: 266  PSTQTTNTTTQKVIIVTTSPS---STFVPNILSKSHNYAAVTKLVPTSVIA-STTQKPPV 321
             S+ +T  TT   +  T+S S   +T +P   + S +    T L  TS+ + ST    P+
Sbjct: 4055 -SSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPL 4113

Query: 322  VITASQSSLVSNSSSGSSSSTP---SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKM 378
             ++++ S+   +S S     TP   +P   T       +S P     T+   + ++A+  
Sbjct: 4114 AVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHT 4173

Query: 379  ASTRLPSP 386
             ST  P P
Sbjct: 4174 RSTAAPIP 4181



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 125/620 (20%), Positives = 214/620 (34%), Gaps = 80/620 (12%)

Query: 310 SVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQ 369
           ++I  +    PV  T S ++ +   S+ +SS T +     ++ ++    T S   ++ AQ
Sbjct: 33  TLITGSKTAAPVTSTGSTTATLEGQSTAASSRTSN---QDISASSQNHQTKSTETTSKAQ 89

Query: 370 GVSTSAIKMASTRLPSPK----SLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQ 425
              T    M ST   SP        + P ++   FP     S    L    +      + 
Sbjct: 90  -TDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPS----SVTNTLMMTSKTITMTTST 144

Query: 426 PSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPI 485
            S + + ++   +        T      S V I   Q   S+      T+   TS++S  
Sbjct: 145 DSTLGNTEETSTAGTESSTPVT------SAVSITAGQEGQSRTTSWR-TSIQDTSASSQN 197

Query: 486 MVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545
               S     TT+   T T T  T + P+ SPS+  +  T    T               
Sbjct: 198 HWTRST---QTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKT--------------- 239

Query: 546 SLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKN----VVT 601
              +  G+  +S++ S T T +    MTS+     +  TT  G+T+ G PG+     V  
Sbjct: 240 ---SPSGETATSSLCSVTNTSM----MTSEK----ITVTTSTGSTL-GNPGETSSVPVTG 287

Query: 602 TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ 661
           +L+       +   P G  PA  + T        ++     S        I T       
Sbjct: 288 SLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPV 347

Query: 662 GKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKE-EPQNYTDSS 720
             + VL  P       TV  E      T T    S  +   N+ +   K        DS+
Sbjct: 348 TTSTVLSSPSGFNPSGTVSQETFPSGETTT----SSPSSVSNTFLVTSKVFRMPTSRDST 403

Query: 721 SSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALL 780
             +TE +  S  S  +  + +     W    ++   SP+ +   +S+   +  S      
Sbjct: 404 LGNTEETSLSV-SGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQS------ 456

Query: 781 ELQQTTVK--EKLESKP--RQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYI 836
           E  +TT +  E+    P   Q    L +          K H+  S +     S   A  +
Sbjct: 457 EGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRL 516

Query: 837 TTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHV----------AQSQTATQTSVVV 886
            T     GT    P + S  S   +P +P  T   H           AQ+Q   +T    
Sbjct: 517 VTGNPSTGTAGTIPRVPSKVSAIGEPGEP-TTYSSHSTTLPKTTGAGAQTQWTQETGTTG 575

Query: 887 KSIPASSPGAITHIMQQALS 906
           +++ +S   ++T +++ A S
Sbjct: 576 EALLSSPSYSVTQMIKTATS 595


>gi|98986457 host cell factor 1 [Homo sapiens]
          Length = 2035

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 151/658 (22%), Positives = 246/658 (37%), Gaps = 153/658 (23%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPA------------------------SNVVVLPS 183
            +T ++PT  PVPS      KSP PA+ A                        + + VLP+
Sbjct: 407  ATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT 466

Query: 184  --GSTVYVKSVSCSDEDEKPRK--------------RRRTNSSSSSPVVLKEVP---KAV 224
              GS++ V + + +       K               R  + +  +PV +  +P   + V
Sbjct: 467  VPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMV 526

Query: 225  VPVSKTITVPVSGSPKMSNIMQSIA-----NSLPPHMSPVKITFTKPSTQTTNTTTQKVI 279
            VP        +  SP+MS +    A       +PP  +P  ++          TT  K +
Sbjct: 527  VPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSV------PAGTTIVKTM 580

Query: 280  IVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSS 339
             VT  P +T +P          A  K+  + V+ S    P   +  + ++ V  S S ++
Sbjct: 581  AVT--PGTTTLP----------ATVKVASSPVMVS---NPATRMLKTAAAQVGTSVSSAT 625

Query: 340  SSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS-TSAIKMASTRLPSPKSLVSAPTQILA 398
            +++  PI        V  +  + V++TV  GV+ T  +  +   +P   +L+S   ++++
Sbjct: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685

Query: 399  QFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGI----------KPT- 447
                        Q   VQ       A   PV+   Q  + PLP G           KPT 
Sbjct: 686  VV----------QTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTT 734

Query: 448  -IQIKQESGVK-----IITQQVQPSKILPKPVT--ATLPTSS----NSPIMVVSSNG--- 492
             I   Q SG       +    V PS   P   T   T+P S+         V SS G   
Sbjct: 735  IITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKS 794

Query: 493  --AIMTTKLVTTPTGTQATYTR--PTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLA 548
               I+TTK++T+ TG  A      P ++   G+   T           G+I+  VP    
Sbjct: 795  PITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMG-- 852

Query: 549  TLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGG 608
              G ++++   VS     +TT         +VV+ TT  G T  G     V T+L  AGG
Sbjct: 853  --GVRLVTPVTVSAVKPAVTT---------LVVKGTT--GVTTLGTVTGTVSTSLAGAGG 899

Query: 609  EKT-------IQTVPTGA-------KPAILTATRPITKMIVTQPKGIGS---TVQPAAKI 651
              T       I T+ T A        P  +T +   T +  T   G+ +   T+QP ++ 
Sbjct: 900  HSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTL--TAAGGLTTPTITMQPVSQP 957

Query: 652  IPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEG 709
                ++    G     +   PV+  A+  +EQ    VT        +A++G   +Q G
Sbjct: 958  TQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVT--------IADSGQGDVQPG 1007



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 220/1140 (19%), Positives = 361/1140 (31%), Gaps = 182/1140 (15%)

Query: 73   DERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPV 132
            D + TTI        + ++ +I G  +  + P        T+      +A I    +  V
Sbjct: 729  DGKPTTIITTTQASGAGTKPTILG--ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGV 786

Query: 133  PAETGSKEVVCYSYTSTTSTPTSTP------VPS--------GSIATVKSPRPASPASNV 178
             +  G K  +    T   ++ T  P      VP         G    V    P  P + +
Sbjct: 787  TSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTIL 846

Query: 179  VVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVP---------VSK 229
              +P G    V  V+ S    KP         ++    L  V   V            S 
Sbjct: 847  RTVPMGGVRLVTPVTVSAV--KPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSA 904

Query: 230  TITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTF 289
            ++  P++    ++ +   + N     +S  + T T     TT T T + +   T      
Sbjct: 905  SLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQ----- 959

Query: 290  VPNILSKSHNYAAVTKLVPTSVIAS-TTQKPPVVITASQS----------SLVSNSSSGS 338
            V  I + S   A     +P S++AS TT++P   +T + S          +LV ++    
Sbjct: 960  VTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCE 1019

Query: 339  SSSTPSPIPNTVAVTAVVSSTP----------------SVVMSTVAQGVSTSAIKMASTR 382
            +  T +    T  V A +   P                S+V STV Q  + S +++ S  
Sbjct: 1020 THETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQ-NGSVVRVCSNP 1078

Query: 383  L--PSPKSLVSAPTQILAQFPKQHQQS-PKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSP 439
                      +  T   +    QH  S P  + ++         A  S  ++ Q+  +  
Sbjct: 1079 PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRA 1138

Query: 440  LPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKL 499
               G    I+I   +G  +   Q   S+   +  +AT  T +        S G ++   +
Sbjct: 1139 CAAGTPAVIRISVATGA-LEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197

Query: 500  VTTPTGTQATYTRPTV--------SPSI-----GRMAATPGAATYVKTTSGS-IITVVPK 545
               P G    + +           SPSI     GR +     A   +++ G+    + P 
Sbjct: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257

Query: 546  SLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLN 605
              +  GG          TT  +T +     P+  V Q  +            N  TT  N
Sbjct: 1258 CESLQGGS-------PSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS-N 1309

Query: 606  AGGEKTI------QTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYG 659
            AG  + +      +T  TG      TAT              G T QP           G
Sbjct: 1310 AGSAQRVCSNPPCETHETGTTHTATTATSN------------GGTGQPEG---------G 1348

Query: 660  QQGKTQVLIKPKPVTFQATVVSEQTRQLVTE------TLQQASRVAEAGNSSIQEG---- 709
            QQ       +    T   T +S     L+ +      T++    VA A + + Q G    
Sbjct: 1349 QQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALL 1408

Query: 710  --------------KEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAME 755
                          +      T ++++ T +  S+QD  P          D  E E    
Sbjct: 1409 APFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAA-------SDQGEVESTQG 1461

Query: 756  TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESK-PRQPTIDLSQMAVPIQMTQE 814
             S  I      + S + T+T+ + L    TTV +      P  P  +  Q++   +    
Sbjct: 1462 DSVNI------TSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLP 1515

Query: 815  KRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVA 874
             R   +S S A++     AE ++  +T E    A  L  +      Q S     +   V 
Sbjct: 1516 PRQLLQSASTALMGES--AEVLSASQTPE-LPAAVDLSSTGEPSSGQESAGSAVVATVVV 1572

Query: 875  QSQTATQTSVVVKSIP----ASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDT 930
            Q    TQ+ V   S+P    A +    T +M   L+        + E   +    EE   
Sbjct: 1573 QPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQA 1632

Query: 931  LDPQTGLFYRSALTQ-----------SQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQT 979
            L  Q  L                   + +  Q +L     E  + Q  T+    T+Q+  
Sbjct: 1633 LAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELA 1692

Query: 980  IHLQADQLQHKLPQMPQLSIRHQKLTPLQQ------------EQAQPKPDVQHTQHPMVA 1027
              +Q  QLQ    Q     +  + L P               E A   P       P  A
Sbjct: 1693 ALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALL-PSTA 1751

Query: 1028 KDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQ 1087
             +   P+     PQ VV     K        + A     + V+P  P      P   E Q
Sbjct: 1752 TESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQ 1811



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 110/481 (22%), Positives = 172/481 (35%), Gaps = 131/481 (27%)

Query: 426 PSPV-SHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT----LPTS 480
           P+PV S    P +SP P    P +Q   + G+ ++ Q        P P T T    LPT 
Sbjct: 414 PNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAA------PAPPTTTTIQVLPTV 467

Query: 481 SNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII 540
             S I V               PT  + T   P V    G  A          TT   ++
Sbjct: 468 PGSSISV---------------PTAAR-TQGVPAVLKVTGPQA----------TTGTPLV 501

Query: 541 TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVV 600
           T+ P S A   GK             +T++P   +   +VV   + +GT I   P  + +
Sbjct: 502 TMRPASQA---GK---------APVTVTSLPAGVR---MVVPTQSAQGTVIGSSPQMSGM 546

Query: 601 TTLLNAGGEKTIQTVPTGAKPAILT--ATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVY 658
             L  A      Q +P  + P +L+  A   I K +   P   G+T  PA          
Sbjct: 547 AAL--AAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTP---GTTTLPAT--------- 592

Query: 659 GQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTD 718
                  V +   PV     V +  TR L T   Q  + V+ A N+S +     P     
Sbjct: 593 -------VKVASSPVM----VSNPATRMLKTAAAQVGTSVSSATNTSTR-----PIITVH 636

Query: 719 SSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSAT-STIK 777
            S + T + Q+    Q V  V+             +  + T++   +S    SA  S + 
Sbjct: 637 KSGTVTVAQQA----QVVTTVVGG-----------VTKTITLVKSPISVPGGSALISNLG 681

Query: 778 ALLELQQTTVKEKLESKPRQPTIDLSQMAV-PI-QMTQEKRHSPESPSIAVVES---ELV 832
            ++ + QT        KP Q +    Q +  P+ Q+ Q K   P    + +V S   +  
Sbjct: 682 KVMSVVQT--------KPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPT 733

Query: 833 AEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPAS 892
               TT+ +  GT+                  P    +  V+ S T   T+ ++K+IP S
Sbjct: 734 TIITTTQASGAGTK------------------PTILGISSVSPSTTKPGTTTIIKTIPMS 775

Query: 893 S 893
           +
Sbjct: 776 A 776


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 231/1194 (19%), Positives = 370/1194 (30%), Gaps = 161/1194 (13%)

Query: 100  VPLMPRLVPQTAFTVTANAVANAAIQ------HNASLPVPAETGSKEVVCYSYTSTTSTP 153
            VP MP   PQ   T       +   Q       + ++ + + TG      ++  S T TP
Sbjct: 1194 VPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTP 1253

Query: 154  TSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSS 213
                  + S  T  S  P  P +   V P  ++    + +      KP   + T  +++S
Sbjct: 1254 LLPATLTSSKPTASSGEPPRPTT--AVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311

Query: 214  PVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNT 273
                     A      T+T+P   +   S  +    N   P  +  + T  +P+  +T  
Sbjct: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371

Query: 274  TTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKP---PVVITASQSSL 330
             T       T P++T      + +      T     S   + +  P   PV  T+  ++ 
Sbjct: 1372 PTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATT 1431

Query: 331  VSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLV 390
               + S   ++ P+ +P   + + V  ST +V+  T AQ  ++++   A T    P + +
Sbjct: 1432 TYPTPSHPETTLPTHVP-PFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTL 1490

Query: 391  SAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQI 450
             A        P     S   Q +      +   +  S  S    P+ +P           
Sbjct: 1491 KATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPT 1550

Query: 451  KQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTT---PTGTQ 507
               +   +       S   P P T   P + +SP    SS G +  T   TT   PT + 
Sbjct: 1551 STRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPF---SSTGPMTATSFKTTTTYPTPSH 1607

Query: 508  ATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKI 567
               T PT  P       TP   T +  T   + T                ++ +GT    
Sbjct: 1608 PQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT-----------SASIHSMPTGTIPPP 1656

Query: 568  TTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTAT 627
            TT+  T   +       T  GT+ Q L   N   T  +        T  T    A  T+T
Sbjct: 1657 TTLKATGSTHTAPTMTLTTSGTS-QALSSLNTAKTSTSLHS----HTSSTHHAEATSTST 1711

Query: 628  RPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL 687
              IT      P   G+                          P  VT   T  S  +   
Sbjct: 1712 TNIT----PNPTSTGT-------------------------PPMTVTTSGTSQSRSSFST 1742

Query: 688  VTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQ-- 745
               +    S  +             P+  + S++S T +  S+    PV H  ++     
Sbjct: 1743 AKTSTSLHSHTSST---------HHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRL 1793

Query: 746  --DWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLS 803
               ++ H     T+P      V++ S   T+T         T             T    
Sbjct: 1794 PTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTH 1853

Query: 804  QMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPS 863
             + +P         S  S     +         TT +    T  A P+  +     Q PS
Sbjct: 1854 TVIIPTHTQMATSASIHSMPTGTIPPP------TTIKATGSTHTAPPMTPTTSGTSQSPS 1907

Query: 864  Q----------PQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSS-HTAFT 912
                       P  T   H  +    + T++  K     +   + H    + S   T FT
Sbjct: 1908 SFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFT 1967

Query: 913  KHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQ---KLSQPPLEQTQLQVKTL 969
             HS   G+         +  P T   +++  T    +  Q       PP   + +   T 
Sbjct: 1968 THSPPTGS-----SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTH 2022

Query: 970  QCFQTKQKQ-----TIH------------LQADQLQHKLPQMPQLSIRHQKLTPLQQEQA 1012
                T   Q     +IH            L+A    H  P M         +T     Q 
Sbjct: 2023 TVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPM--------TVTTSGTSQT 2074

Query: 1013 QPKPDVQHTQHPMVAKDRQLP-TLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQP 1071
                         ++    LP    ++PP + +       T QLP L  A        Q 
Sbjct: 2075 HSSFSTATASSSFISSSSWLPQNSSSRPPSSPI-------TTQLPHLSSATTPVSTTNQL 2127

Query: 1072 QTPQS-QMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTS 1130
             +  S   S P++      S    P  +  S  T  +F    P   T ++ GS     T 
Sbjct: 2128 SSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVS-APVHSTTLSSGSHSSLSTH 2186

Query: 1131 PVT---SISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSL 1187
            P T   S SP+  S   A             I   + H I  P   +    + T      
Sbjct: 2187 PTTASVSASPLFPSSPAA----------STTIRATLPHTISSPFTLSALLPISTVTVSPT 2236

Query: 1188 PSTHMVVAGMA-NSTPQQQKCRESC---SSPSTV--GSSLTTRKIDPPAVPATG 1235
            PS+H+  + +A  STP+      +    SS ST    +SLTTR      VP +G
Sbjct: 2237 PSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTR------VPTSG 2284



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 200/945 (21%), Positives = 297/945 (31%), Gaps = 144/945 (15%)

Query: 426  PSPVSHQQ--QPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP--TSS 481
            PSP S+     P Q+PL P    + +    SG        +P    P+P TA  P  TS 
Sbjct: 1238 PSPSSNHTPASPTQTPLLPATLTSSKPTASSG--------EP----PRPTTAVTPQATSG 1285

Query: 482  NSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541
              P   + S          T PT TQAT TR T S       A+P   +  ++T+ + +T
Sbjct: 1286 LPPTATLRSTA--------TKPTVTQAT-TRATAS------TASPATTSTAQSTTRTTMT 1330

Query: 542  V-VPKSLATLGGKIISSNI-VSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNV 599
            +  P +  T      S+N  + GTT   TT P  +  +      TTG  T   G P +  
Sbjct: 1331 LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPAS------TTGPTTPQPGQPTRPT 1384

Query: 600  VTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKI--- 656
             T        +T QT  T         T P T      P   GS V     +  T     
Sbjct: 1385 AT--------ETTQTRTT------TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHAT 1430

Query: 657  -VYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQN 715
              Y      +  +      F  ++V+  T  ++T T   A     A N S   G   P  
Sbjct: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPT--HAQMATSASNHSAPTGTIPPPT 1488

Query: 716  Y---------------TDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTI 760
                            T S +S   SS S+  +   +H   S        E+   ++ TI
Sbjct: 1489 TLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLH---SHTSSTHHPEVTPTSTTTI 1545

Query: 761  IYQDVSSESQSATSTIKALLELQQ----TTVKEKLESKPRQPTIDLSQMAVPIQMTQEKR 816
                 S+ +++  +   +    +     TT      S P   T  ++  +     T    
Sbjct: 1546 TPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTP 1605

Query: 817  HSPESP---SIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHV 873
              P++     +    + LV     T  T    ++A     S  S P     P  TL +  
Sbjct: 1606 SHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATS--ASIHSMPTGTIPPPTTL-KAT 1662

Query: 874  AQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDP 933
              + TA   ++       +     T     +L SHT+ T H+E   T    +    T   
Sbjct: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPT--- 1719

Query: 934  QTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQ 993
             TG    +  T   S  +   S                   K   ++H       H  P+
Sbjct: 1720 STGTPPMTVTTSGTSQSRSSFS-----------------TAKTSTSLHSHTSSTHH--PE 1760

Query: 994  MPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMA--QPPQTVVQVLA--- 1048
            +   S     +TP         P      H   A   +LPT      PP     + +   
Sbjct: 1761 VTSTST--TSITPNHTSTGTRTP----VAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814

Query: 1049 -VKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKIT 1107
               T+ Q       P+ P   +    P    SL   S           + T  +S+  + 
Sbjct: 1815 VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMAT-SASIHSMP 1873

Query: 1108 FEGRQPPTVTKITGGS-SVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHM 1166
                 PPT  K TG + + P +T   +  S   +S  TA     K S       ++  H 
Sbjct: 1874 TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTA-----KTSTSLPYHTSSTHHP 1928

Query: 1167 IVDPPKKALATSMLTGEAGSLPSTHMVVAG-------MANSTPQQQKCRESCSSPSTVGS 1219
             V P      T   T      P  H   A            +P       S + P T  S
Sbjct: 1929 EVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATS 1988

Query: 1220 SLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPC--HSSSNVVVEP 1277
              TT     P+ P T     +          S   +II    Q A     HS+    V P
Sbjct: 1989 FQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPP 2048

Query: 1278 SGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS 1322
               L+    T        TA    + +S    T  S S ++A  S
Sbjct: 2049 PTTLKATGST-------HTAPPMTVTTSGTSQTHSSFSTATASSS 2086



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 120/479 (25%), Positives = 178/479 (37%), Gaps = 70/479 (14%)

Query: 110  TAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSP 169
            T    T   +A +A  H+    +P  T        +  ST + P  TP  SG   T +SP
Sbjct: 1854 TVIIPTHTQMATSASIHS----MPTGTIPPPTTIKATGSTHTAPPMTPTTSG---TSQSP 1906

Query: 170  RPASPASNVVVLP--SGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVV-LKEVPKAVVP 226
               S A     LP  + ST + +    S  +  P+    T++ + +PV        + +P
Sbjct: 1907 SSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPK---HTSTGTRTPVAHTTSASSSRLP 1963

Query: 227  VSKTITVPVSGSPKMSNIMQSIANS----------------LPPHMSPVKITFTKPSTQT 270
               T   P +GS   S+     A S                LP H+ P   +   PST T
Sbjct: 1964 TPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHT 2023

Query: 271  TNTTTQKVIIVTTS----PSSTFVPNILSKS--HNYAAVTKLVPTSVIASTTQKPPVVIT 324
               TT   +  + S    P+ T  P    K+    + A    V TS    T+Q      T
Sbjct: 2024 VIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTS---GTSQTHSSFST 2080

Query: 325  ASQSSLVSNSSSG---SSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAST 381
            A+ SS   +SSS    +SSS P   P T  +  + S+T  V  ST  Q        ++S+
Sbjct: 2081 ATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPV--STTNQ--------LSSS 2130

Query: 382  RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQS--- 438
              PSP    SAP+ + +  P  H  SP+     V   +    A     +       S   
Sbjct: 2131 FSPSP----SAPSTVSSYVPSSHS-SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185

Query: 439  -PLPPGIKPTIQIKQESGVKIITQQVQPSKIL-PKPVTATLPTSSNSPIMVVSSNGAIMT 496
             P    +  +             +   P  I  P  ++A LP S+ +     SS+ A  T
Sbjct: 2186 HPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245

Query: 497  TKLVTTPTGTQATYTRP------TVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLAT 549
                +TP  T +T+T P      T S S       P  + +V  TSG  +T +P S  T
Sbjct: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVP-TSGFVSLTSG--VTGIPTSPVT 2301



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 66/279 (23%), Positives = 117/279 (41%), Gaps = 28/279 (10%)

Query: 88   SSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYT 147
            SSS W  +     P    +  Q     +A    +   Q ++S   P+ +    V  Y  +
Sbjct: 2089 SSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFS-PSPSAPSTVSSYVPS 2147

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASN-----VVVLPSGSTVYVKSVSCSDEDEKPR 202
            S +S  TS+P    S + V +P  ++  S+     +   P+ ++V    +  S       
Sbjct: 2148 SHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTT 2207

Query: 203  KRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262
             R     + SSP  L     A++P+S T+TV    SP  S+ + S   + P        T
Sbjct: 2208 IRATLPHTISSPFTLS----ALLPIS-TVTV----SPTPSSHLASSTIAFPSTPRTTAST 2258

Query: 263  FTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVV 322
             T P+  + +TT++   + T  P+S FV        +  +    +PTS + + T + P  
Sbjct: 2259 HTAPAFSSQSTTSRSTSLTTRVPTSGFV--------SLTSGVTGIPTSPVTNLTTRHPGP 2310

Query: 323  ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS 361
             T S ++    SS  +  STP+  P    V+++ + TP+
Sbjct: 2311 -TLSPTTRFLTSSLTAHGSTPASAP----VSSLGTPTPT 2344



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 73/304 (24%), Positives = 108/304 (35%), Gaps = 53/304 (17%)

Query: 148  STTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSG--------STVYVKSVSCSDEDE 199
            S  STPT T  P  ++    S   A P   + V  SG        ST    S   S    
Sbjct: 2037 SIHSTPTGTVPPPTTLKATGSTHTAPP---MTVTTSGTSQTHSSFSTATASSSFISSSSW 2093

Query: 200  KPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP--HMS 257
             P+       SS     L  +  A  PVS T  +  S SP  S    S  +S  P  H S
Sbjct: 2094 LPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPS--APSTVSSYVPSSHSS 2151

Query: 258  PVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQ 317
            P     + PS  T+++     +  TT  S +        +    + + L P+S  ASTT 
Sbjct: 2152 PQT---SSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTI 2208

Query: 318  KPPVVITASQ-----------SSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPS----- 361
            +  +  T S            +  VS + S   +S+    P+T   TA   + P+     
Sbjct: 2209 RATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQS 2268

Query: 362  -----------------VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404
                             V +++   G+ TS +   +TR P P   +S  T+ L      H
Sbjct: 2269 TTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGP--TLSPTTRFLTSSLTAH 2326

Query: 405  QQSP 408
              +P
Sbjct: 2327 GSTP 2330


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 158/693 (22%), Positives = 243/693 (35%), Gaps = 112/693 (16%)

Query: 409  KQQLYQVQQQTQQQVAQPSPVSHQQQPQ-QSPLPPGIKPTIQIKQ-ESGVKIITQQVQPS 466
            K+ L   Q+  Q  VAQP P   Q  P  Q P PP  +P     Q  +G   +  Q QP 
Sbjct: 2489 KKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQ 2548

Query: 467  -KILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAAT 525
             +  P+PV A    +   P +    + A++   + T+ TGT       + +  +  +A  
Sbjct: 2549 PQTQPQPVQA---PAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGV 2605

Query: 526  PGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTT 585
            P AAT+          V P +L T GG   +  + +    +    P T+ P+++ +  T 
Sbjct: 2606 P-AATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQ 2664

Query: 586  GKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTV 645
            G    +  +    VVTT L       +QT      P +  AT       V  P   G T+
Sbjct: 2665 GV-RAVTSVTASAVVTTNLT-----PVQTPARSLVPQVSQATG------VQLP---GKTI 2709

Query: 646  QPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSS 705
             PA                          FQ     +Q +Q   +  QQ  +        
Sbjct: 2710 TPA-------------------------HFQLLRQQQQQQQQQQQQQQQQQQ-------- 2736

Query: 706  IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDV 765
             Q+ +++ Q    +++S  +  Q    +Q    + A  +    EH I M+          
Sbjct: 2737 -QQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLT-PEHLIKMQ---------- 2784

Query: 766  SSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIA 825
                       K  L++       + +S P QPT       V +Q +Q  +   +SP + 
Sbjct: 2785 -----------KQKLQMPPQPPPPQAQSAPPQPTAQ-----VQVQTSQPPQQ--QSPQLT 2826

Query: 826  VVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV 885
             V +      +T      GT VA   +      P    Q Q  +     Q          
Sbjct: 2827 TVTAPRPGALLT------GTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPP 2880

Query: 886  VKSIPA---SSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSA 942
            V S+PA   SSPG  T  M  A  S  A  +  +  G          T+  Q     +  
Sbjct: 2881 VVSVPAAVVSSPGVTTLPMNVAGIS-VAIGQPQKAAG---------QTVVAQPVHMQQLL 2930

Query: 943  LTQSQSAKQQKLSQPPLEQTQLQVK---TLQCFQTKQKQTIHLQADQLQHKLPQMPQLSI 999
              + Q+ +QQK  QP   Q    V+   T Q   T   Q     A Q   K   +     
Sbjct: 2931 KLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPIS 2990

Query: 1000 RHQKLTPLQQEQAQPK----PDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQL 1055
            + QKL   QQ Q Q +    P V   Q P+ +  +         PQTV    A    QQ+
Sbjct: 2991 QAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQV 3050

Query: 1056 PKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088
              +       ++ VQ +  Q Q+   AS+  QT
Sbjct: 3051 QMIPAVTATAQV-VQQKLIQQQVVTTASAPLQT 3082



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 126/562 (22%), Positives = 213/562 (37%), Gaps = 58/562 (10%)

Query: 267  STQTTNTTTQKVIIVTTS--PSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVIT 324
            ++  T   +  VI+ T +  P++TF      +S N    + + P ++       P  V+ 
Sbjct: 2586 TSMPTGAVSGNVIVNTIAGVPAATF------QSINKRLASPVAPGALTTPGGSAPAQVVH 2639

Query: 325  ASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMA----- 379
                     S + ++    S +  T  V AV S T S V++T    V T A  +      
Sbjct: 2640 TQPPPRAVGSPATATPDLVS-MATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQ 2698

Query: 380  --STRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQT-----QQQVAQPSPVSHQ 432
                +LP  K++  A  Q+L Q  +Q QQ  +QQ  Q QQQ      QQQ    S V   
Sbjct: 2699 ATGVQLPG-KTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVP 2757

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNG 492
            Q   Q+  P  IK   ++  E  +K+  Q++Q     P P   + P    + + V +S  
Sbjct: 2758 QIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQP 2817

Query: 493  AIMTTKLVTTPTGTQ--ATYTRPTVSP-SIGRMAATPGAATYVKTTSGSIITVVPK--SL 547
                +  +TT T  +  A  T  TV+   + R+   P   T      G + T  P+   +
Sbjct: 2818 PQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVP---TSQLQAQGQMQTQAPQPAQV 2874

Query: 548  ATLGGKIISSNIVSGTTTKITTIPM-TSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNA 606
            A     ++S      ++  +TT+PM  +  +V + Q     G T+   P        L  
Sbjct: 2875 ALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQ 2934

Query: 607  GGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQV 666
               +  + +   A        + IT   +T P         A   + T+ +     + Q 
Sbjct: 2935 QAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQK 2994

Query: 667  LIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTES 726
            L   + V  Q  V        + + +QQ + VA     SIQ+     Q  +  + + T++
Sbjct: 2995 LAGAQQVQTQIQVAK------LPQVVQQQTPVA-----SIQQVASASQQASPQTVALTQA 3043

Query: 727  SQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTT 786
            + + Q  Q +  V A+          A      +I Q V + + +   T  A    Q   
Sbjct: 3044 TAAGQQVQMIPAVTAT----------AQVVQQKLIQQQVVTTASAPLQTPGAPNPAQ--- 3090

Query: 787  VKEKLESKPRQPTIDLSQMAVP 808
            V    +S  +QP +   QM VP
Sbjct: 3091 VPASSDSPSQQPKL---QMRVP 3109



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 48/167 (28%), Positives = 69/167 (41%), Gaps = 25/167 (14%)

Query: 382 RLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ-QVAQPSPVSHQQQPQQSPL 440
           RLP P  + +A      QF +Q Q    Q   Q+  +TQQ  V  P+P S      Q P+
Sbjct: 559 RLP-PAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPS-----SQLPI 612

Query: 441 PPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT-------------LPTSSNSPIMV 487
           PP     + +   +  K+  Q  Q S  LP+ V +T             LPTSS S +  
Sbjct: 613 PPSQPAQLALHVPTPGKVQVQASQLSS-LPQMVASTRLPVDPAPPCPRPLPTSSTSSLAP 671

Query: 488 VSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKT 534
           VS +G    +   ++P    ++ T   +SP   R   TPG      T
Sbjct: 672 VSGSGP-GPSPARSSPVNRPSSATNKALSPVTSR---TPGVVASAPT 714



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 65/325 (20%), Positives = 107/325 (32%), Gaps = 18/325 (5%)

Query: 945  QSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQAD-QLQHKLPQMPQLSIRHQK 1003
            Q Q  +QQ+  Q   +Q Q Q +  Q   T Q Q   +Q   Q   ++  + +L+  H  
Sbjct: 2722 QQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLI 2781

Query: 1004 LTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPN 1063
                Q+ Q  P+P     Q        Q+    +QPPQ     L   T  +   L     
Sbjct: 2782 KMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTT 2841

Query: 1064 QPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKI---T 1120
               + V   T      L A  + QT +     +      V  +       P VT +    
Sbjct: 2842 VANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNV 2901

Query: 1121 GGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSML 1180
             G SV  +  P  +      ++   +  +LK+     Q    ++      P  A     +
Sbjct: 2902 AGISV-AIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGP--AAVQQKI 2958

Query: 1181 TGEAGSLPSTHMVVAGMAN--------STPQQQKCRESCSSPSTVGSSLTTRKIDPPAVP 1232
            T +  + P     VA  A         +TP  Q   +  +    V + +   K+ P  V 
Sbjct: 2959 TAQQITTPGAQQKVAYAAQPALKTQFLTTPISQ--AQKLAGAQQVQTQIQVAKL-PQVVQ 3015

Query: 1233 ATGQFMRIQNVGQKKAEESPAEIII 1257
                   IQ V     + SP  + +
Sbjct: 3016 QQTPVASIQQVASASQQASPQTVAL 3040



 Score = 37.7 bits (86), Expect = 0.074
 Identities = 65/274 (23%), Positives = 102/274 (37%), Gaps = 30/274 (10%)

Query: 991  LPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVK 1050
            LP +   S+R +++   ++  A    D Q  Q P VA   Q P    QPP    Q     
Sbjct: 2472 LPPIQVASLRAERIAKEKKALA----DQQKAQQPAVA---QPPPPQPQPPPPPQQ----- 2519

Query: 1051 TTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEG 1110
                LP+ Q A +QP        PQ Q       +   A    QP IT G S   +    
Sbjct: 2520 PPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTI 2579

Query: 1111 RQPPTVTKI-TGGSSVPKLTSPVTSI--SPIQASEKTAVSDILKMSLMEAQIDTNVEHMI 1167
            +   T T + TG  S   + + +  +  +  Q+  K   S +   +L         + + 
Sbjct: 2580 KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVH 2639

Query: 1168 VDPPKKALAT-SMLTGEAGSLPSTHMVVAGMA---------NSTPQQQKCRESCSSPS-T 1216
              PP +A+ + +  T +  S+ +T  V A  +         N TP Q   R      S  
Sbjct: 2640 TQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQA 2699

Query: 1217 VGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEE 1250
             G  L  + I     PA  Q +R Q   Q++ ++
Sbjct: 2700 TGVQLPGKTI----TPAHFQLLRQQQQQQQQQQQ 2729



 Score = 34.7 bits (78), Expect = 0.62
 Identities = 51/247 (20%), Positives = 90/247 (36%), Gaps = 33/247 (13%)

Query: 992  PQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTL------------MAQP 1039
            PQ  QL+ + Q           P  +      P+     +LP               AQ 
Sbjct: 520  PQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQ 579

Query: 1040 PQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQ 1099
            PQ    V+  +T  Q+P   Q PN P     P  P SQ+ +P S   Q A  V  P    
Sbjct: 580  PQ----VVEAQTQLQIPVKTQQPNVP----IPAPPSSQLPIPPSQPAQLALHVPTP---- 627

Query: 1100 GSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQI 1159
                 K+  +  Q  ++ ++   + +P   +P     P+  S  ++++ +       +  
Sbjct: 628  ----GKVQVQASQLSSLPQMVASTRLPVDPAPPCP-RPLPTSSTSSLAPVSGSGPGPSPA 682

Query: 1160 DTNVEHMIVDPPKKALA--TSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTV 1217
             ++  +       KAL+  TS   G   S P+     A   N+T  Q   +++ +   T+
Sbjct: 683  RSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPA--QNATSSQDSSQDTLTEQITL 740

Query: 1218 GSSLTTR 1224
             + +  R
Sbjct: 741  ENQVHQR 747


>gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial
           [Homo sapiens]
          Length = 1063

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 126/560 (22%), Positives = 210/560 (37%), Gaps = 63/560 (11%)

Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204
           S TST ST  STP  + SI T ++   ++P+    +  + +T +  + S +  +     R
Sbjct: 83  SITSTESTSHSTPPFTSSITTNETTSHSTPSFTTSITKTKTTSH-STPSFTSSNSITDSR 141

Query: 205 RRTNSSSSSPVVLKEVPKAVVP--VSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262
             +    +S V   E+     P  +S  IT   +     S    +I +++    + +   
Sbjct: 142 SHSTPPFTSSVTTPEMTSHNTPSFMSSIITTETTSHSTPSFTSSTIHSTVSSSTTAITSP 201

Query: 263 FTKPSTQTTNTTTQKVIIVTTSPSS---TFVPNILSKSHNYAAVTKL--VPTSVIASTTQ 317
           FT   T  T+T +    + T  P++   T  P  LS S +    T L  +PT + +  T 
Sbjct: 202 FTTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLSLSTSTSLTTTTDLPSIPTDISSLPT- 260

Query: 318 KPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVT-AVVSSTPSVVMSTVAQGVSTSAI 376
             P+ I +S  S+ S  +S S   T SP  +TV  T     +TP    ST       +  
Sbjct: 261 --PIHIISSSPSIQSTETS-SLVGTTSPTMSTVRATLRSTENTPISSFSTSIVVTPETPT 317

Query: 377 KMASTRLPSPKSLVSAPTQILAQFPKQ-------HQQSPKQQLYQVQQQTQQQVAQPSPV 429
             A   L S     ++P      F          H  +P   L ++   +Q     P P 
Sbjct: 318 TQAPPVLMSATGTQTSPVPTTVTFGSMDSSTSTLHTLTPSTALSKIMSTSQ----FPIPS 373

Query: 430 SHQQQPQQSPLPPGIKPTIQIKQE-------------------------SGVKIITQQVQ 464
           +H    Q +P  P ++ ++    E                         S    I     
Sbjct: 374 THSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSS 433

Query: 465 PSKILPKPVTA-TLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSP-SIGRM 522
           PS     PV A T+ +  +SP +  + N    +     + + +  T T PT S  +    
Sbjct: 434 PSSASITPVFATTIHSVPSSPYIFSTENVGSASITAFPSLSSSSTTSTSPTSSSLTTALT 493

Query: 523 AATPGAATYVKTTS---GSI-ITVVPKSLATLGGKI-ISSNIVSGTTTKITTIPMTSK-- 575
             TP +   + +T+   G+I IT+VP S      ++  S+   S  TT +T  P T++  
Sbjct: 494 EITPFSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMV 553

Query: 576 --PNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKM 633
             P+ I +Q T         +  ++  + + NA       TVPT     + T+TR  T  
Sbjct: 554 TCPSSISMQTTLATHMDTSSMTPESESSIIPNASSSTGTGTVPTN---TVFTSTRLPTSE 610

Query: 634 IVTQPKGIGSTVQPAAKIIP 653
                  +  T  P    IP
Sbjct: 611 TWLSNNSVIPTPLPGVSTIP 630



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 151/705 (21%), Positives = 256/705 (36%), Gaps = 144/705 (20%)

Query: 267 STQTTNTTTQKVI--IVTTSPSSTFVPNILSK-------SHNYAAVTKLVPTSVIAS-TT 316
           +T+TT+ +T      IVTT  +S   P   S         H+    T L+ TS + S +T
Sbjct: 1   TTETTSRSTPGFTSSIVTTETTSPHTPGFTSSITTTETIPHSTPTFTSLITTSEMTSHST 60

Query: 317 QKPPVVITASQSSLVSNSSSGSS-SSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSA 375
                 IT ++S+  S  S  SS +ST S   +T   T+ +++  +   ST +   S + 
Sbjct: 61  PSLTFSITTTKSTSYSPPSFTSSITSTESTSHSTPPFTSSITTNETTSHSTPSFTTSITK 120

Query: 376 IKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQP 435
            K  S   PS  S  S          + H   P              V  P   SH    
Sbjct: 121 TKTTSHSTPSFTSSNSITDS------RSHSTPP----------FTSSVTTPEMTSHN--- 161

Query: 436 QQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPI-MVVSSNGAI 494
                                   T     S I  +  + + P+ ++S I   VSS+   
Sbjct: 162 ------------------------TPSFMSSIITTETTSHSTPSFTSSTIHSTVSSSTTA 197

Query: 495 MTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKI 554
           +T+   T  TG  +T + P+              +T + TT  S+ T+ P SL+T     
Sbjct: 198 ITSPFTTAETGVTSTPSSPS------------SLSTDIPTT--SLRTLTPLSLSTSTSLT 243

Query: 555 ISSNIVSGTTTKITTIP-----MTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE 609
            ++++ S   T I+++P     ++S P++   + ++  GTT    P  + V   L +   
Sbjct: 244 TTTDLPS-IPTDISSLPTPIHIISSSPSIQSTETSSLVGTT---SPTMSTVRATLRSTEN 299

Query: 610 KTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYG-QQGKTQVLI 668
             I +  T     ++T   P T+         G+   P    +PT + +G     T  L 
Sbjct: 300 TPISSFSTS---IVVTPETPTTQAPPVLMSATGTQTSP----VPTTVTFGSMDSSTSTLH 352

Query: 669 KPKPVTFQATVVSEQTRQLV---TETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST- 724
              P T  + ++S     +    + TLQ    +     S     +   +++T  S+S+  
Sbjct: 353 TLTPSTALSKIMSTSQFPIPSTHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNA 412

Query: 725 ------------------ESSQSSQDSQPV----VHVIASRRQDWSEHEI---AMETSPT 759
                              SS SS    PV    +H + S    +S   +   ++   P+
Sbjct: 413 ILTSFSTIIWSSTPTIIMSSSPSSASITPVFATTIHSVPSSPYIFSTENVGSASITAFPS 472

Query: 760 IIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSP 819
           +     +S S +++S   AL E+   +      + P   TI ++ +             P
Sbjct: 473 LSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGTITITIV-------------P 519

Query: 820 ESPSIAVVESELVAEYITTERTDEGTE--VAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQ 877
            SP+   VE +      +TE T   T     FP      + P   S  Q TL  H+  S 
Sbjct: 520 ASPTDPCVEMD-----PSTEATSPPTTPLTVFPFTTEMVTCPSSISM-QTTLATHMDTSS 573

Query: 878 TATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEE 922
              ++   +    +SS G  T      + ++T FT  S  L T E
Sbjct: 574 MTPESESSIIPNASSSTGTGT------VPTNTVFT--STRLPTSE 610



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 103/501 (20%), Positives = 195/501 (38%), Gaps = 76/501 (15%)

Query: 148 STTSTPTSTPVPSGSIATVKSPRPASPA-----SNVVVLPSGSTVYVKSVSCSDEDEKPR 202
           +T +T  STP  + SI T ++  P +P      +    +P  +  +   ++ S+      
Sbjct: 1   TTETTSRSTPGFTSSIVTTETTSPHTPGFTSSITTTETIPHSTPTFTSLITTSEM----- 55

Query: 203 KRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKIT 262
                 +S S+P     +  ++     T   P S +  +++  +S ++S PP  S +   
Sbjct: 56  ------TSHSTP----SLTFSITTTKSTSYSPPSFTSSITST-ESTSHSTPPFTSSI--- 101

Query: 263 FTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQK-PPV 321
                  TTN TT      +T   +T +    + SH+  + T     S+  S +   PP 
Sbjct: 102 -------TTNETTSH----STPSFTTSITKTKTTSHSTPSFTS--SNSITDSRSHSTPPF 148

Query: 322 VITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMAS- 380
             + +   + S++       TPS + + +       STPS   ST+   VS+S   + S 
Sbjct: 149 TSSVTTPEMTSHN-------TPSFMSSIITTETTSHSTPSFTSSTIHSTVSSSTTAITSP 201

Query: 381 --TRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPS-PVSHQQQPQQ 437
             T      S  S+P+ +    P    ++                  PS P      P  
Sbjct: 202 FTTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLSLSTSTSLTTTTDLPSIPTDISSLPTP 261

Query: 438 SPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT 497
             +     P+IQ  + S +   T     +      V ATL ++ N+PI       +  +T
Sbjct: 262 IHIISS-SPSIQSTETSSLVGTTSPTMST------VRATLRSTENTPI-------SSFST 307

Query: 498 KLVTTPTGTQATYTRPTVSPSIG-RMAATPGAATY--VKTTSGSIITVVPKSLATLGGKI 554
            +V TP  T  T   P +  + G + +  P   T+  + +++ ++ T+ P   +T   KI
Sbjct: 308 SIVVTPE-TPTTQAPPVLMSATGTQTSPVPTTVTFGSMDSSTSTLHTLTP---STALSKI 363

Query: 555 ISSNIVSGTTTKITTIPMT-SKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQ 613
           +S++     +T  +T+  T S P++     +T + TT     G      +L      +  
Sbjct: 364 MSTSQFPIPSTHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILT-----SFS 418

Query: 614 TVPTGAKPAILTATRPITKMI 634
           T+   + P I+ ++ P +  I
Sbjct: 419 TIIWSSTPTIIMSSSPSSASI 439



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 108/491 (21%), Positives = 182/491 (37%), Gaps = 76/491 (15%)

Query: 77  TTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAET 136
           T +    S P+S S   I    L  L P L   T+ ++T      +     +SLP P   
Sbjct: 207 TGVTSTPSSPSSLST-DIPTTSLRTLTP-LSLSTSTSLTTTTDLPSIPTDISSLPTPIHI 264

Query: 137 GSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRP---ASPASNVVVLPSGSTVYVKSVS 193
            S      S  +++   T++P  S   AT++S      +S ++++VV P   T     V 
Sbjct: 265 ISSSPSIQSTETSSLVGTTSPTMSTVRATLRSTENTPISSFSTSIVVTPETPTTQAPPVL 324

Query: 194 CSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLP 253
            S              + +SPV       ++   + T+   ++ S  +S IM +    +P
Sbjct: 325 MS-----------ATGTQTSPVPTTVTFGSMDSSTSTLHT-LTPSTALSKIMSTSQFPIP 372

Query: 254 P-HMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNIL----------------SK 296
             H S ++ T + PS QT+ T+T +    + +  ST    IL                S 
Sbjct: 373 STHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSS 432

Query: 297 SHNYAAVTKLVPTSV--------IASTTQKPPVVITA----SQSSLVSNSSSGSSSSTP- 343
           S + A++T +  T++        I ST       ITA    S SS  S S + SS +T  
Sbjct: 433 SPSSASITPVFATTIHSVPSSPYIFSTENVGSASITAFPSLSSSSTTSTSPTSSSLTTAL 492

Query: 344 --------------SPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSL 389
                         +P P T+ +T V +S     +       +TS      T  P    +
Sbjct: 493 TEITPFSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEM 552

Query: 390 VSAPTQI-----LAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPP-- 442
           V+ P+ I     LA        +P+ +   +   +        P +      + P     
Sbjct: 553 VTCPSSISMQTTLATHMDTSSMTPESESSIIPNASSSTGTGTVPTNTVFTSTRLPTSETW 612

Query: 443 ----GIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTK 498
                + PT       GV  I   ++PS  LP  +  +  ++  SP    +S  ++ TT+
Sbjct: 613 LSNNSVIPT----PLPGVSTIPLTMKPSSSLPTILRTSSKSTHPSPPTARTSETSVATTQ 668

Query: 499 LVTTPTGTQAT 509
             TT T  + T
Sbjct: 669 TPTTLTTRRTT 679



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 61/247 (24%), Positives = 95/247 (38%), Gaps = 21/247 (8%)

Query: 137 GSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSD 196
           GS  +  +   S++ST +++P  S     +    P S  S     P   T+ +  V  S 
Sbjct: 463 GSASITAFPSLSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASP 522

Query: 197 EDEKPRKRRRTNSSSSSPVVLKEVPKAVVP-VSKTITVPVSGSPKMSNIMQSIANSLPPH 255
            D  P      ++ ++SP      P  V P  ++ +T P S S + +       +S+ P 
Sbjct: 523 TD--PCVEMDPSTEATSPPT---TPLTVFPFTTEMVTCPSSISMQTTLATHMDTSSMTPE 577

Query: 256 MSPVKITFTKPSTQTTNTTTQKVIIVTTSPSS-TFVPNILSKSHNYAAVTKLVPTSVIAS 314
                I     ST T    T  V   T  P+S T++ N      N    T L   S I  
Sbjct: 578 SESSIIPNASSSTGTGTVPTNTVFTSTRLPTSETWLSN------NSVIPTPLPGVSTIP- 630

Query: 315 TTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTS 374
            T KP        SSL +   + S S+ PSP     + T+V ++     ++T      TS
Sbjct: 631 LTMKP-------SSSLPTILRTSSKSTHPSPPTARTSETSVATTQTPTTLTTRRTTPITS 683

Query: 375 AIKMAST 381
            +   ST
Sbjct: 684 WMTTQST 690


>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
           [Homo sapiens]
          Length = 909

 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 126/626 (20%), Positives = 244/626 (38%), Gaps = 60/626 (9%)

Query: 145 SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204
           S T+T +T  STP  + SI+T ++   ++P+   ++  + +T +  + S +         
Sbjct: 34  SITTTETTSHSTPSFTSSISTTETTSHSTPSFTSLITITETTSH-STPSYTTSITTTETP 92

Query: 205 RRTNSSSSSPVVLKEVPKAVVP-VSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITF 263
             +  S ++ +   E P    P  + +IT   + S    +   SI  +     S    T 
Sbjct: 93  SHSTPSYTTSITTTETPSHSTPSFTSSITTTETTSHSTPSFTSSIRTTETTSYSTPSFTS 152

Query: 264 TKPSTQTTNTTTQKVI--IVTTSPSSTFVPNILSK-------SHNYAAVTKLVPTSVIA- 313
           +   T+TT+ +T   I  I TT   S+  P+  S        SH+    T  + T+    
Sbjct: 153 SNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTETTS 212

Query: 314 -STTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            ST      + T   +S  + S + S +++ +P  +T + T+++++T +   ST +    
Sbjct: 213 HSTPSFTSSITTTETTSHDTPSFTSSITTSETPSHSTPSSTSLITTTKTTSHSTPS---F 269

Query: 373 TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
           TS+I    T   S  S  S+ T    +    + +S    +   +  +    +  S ++  
Sbjct: 270 TSSITTTETTSHSAHSFTSSIT--TTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTT 327

Query: 433 QQPQQS-PLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS---NSPIMVV 488
           +    S P       T +             V P+ + P  ++  +PT+S    +P  V 
Sbjct: 328 ETTSHSTPSFSSSITTTETXXXXXXXTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVG 387

Query: 489 SSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLA 548
           +S     TT   + PT      TR  +  S   + +T   ++ V TTS ++ TV      
Sbjct: 388 TSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTE-TSSLVGTTSPTMSTV------ 440

Query: 549 TLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGG 608
            +  +I  +  +S  +T I  IP T      V+   TG  T+    P    VT       
Sbjct: 441 RMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTS----PAPTTVTFGSTDSS 496

Query: 609 EKTIQTV-PTGAKPAILTATRPITKMIVTQPKGIGSTVQ--PAAKIIPTKIVYGQQGKTQ 665
             T+ T+ P+ A   I++ ++      V  P    ST+Q  P+   + T +    +  T+
Sbjct: 497 TSTLHTLTPSTALSTIVSTSQ------VPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTE 550

Query: 666 VLIKPKP-----VTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEP------- 713
              +        +T  +T++   T  ++  +   ++ +    +++I      P       
Sbjct: 551 SFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTEN 610

Query: 714 ------QNYTDSSSSSTESSQSSQDS 733
                   +   SSS+T S+ S+  S
Sbjct: 611 VGSASITGFPSLSSSATTSTSSTSSS 636



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 121/591 (20%), Positives = 214/591 (36%), Gaps = 88/591 (14%)

Query: 108 PQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPS--GSIAT 165
           P  + ++T     + +     S     ET S     ++ + TT+  TS   PS   SI T
Sbjct: 182 PSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHDTPSFTSSITT 241

Query: 166 VKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVV 225
            ++P  ++P+S  ++  + +T +      S            +S +SS    +       
Sbjct: 242 SETPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTETTSHNTR 301

Query: 226 PVSKTITVPVSGSPKMSNIMQSI------ANSLPPHMSPVKITFTKPS----------TQ 269
             + +IT   + S   ++   SI      ++S P   S +  T T             T 
Sbjct: 302 SFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETXXXXXXXTSETAVTP 361

Query: 270 TTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKL--VPTSVIASTTQKPPVVITASQ 327
           T  T +     + T+   T  P+ +  S +    T    +PT +    T+   +  + S 
Sbjct: 362 TPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSI 421

Query: 328 SSLVSNSSSGSSSSTPSPIPNTVAVT------------AVVSSTPSVV--MSTVAQGVST 373
            S  ++S  G++S T S +  T+ +T             V+  TP+    + T A G  T
Sbjct: 422 QSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQT 481

Query: 374 SAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQ 433
           S         P+P ++    T   +     H  +P   L  +   +Q     P P +H  
Sbjct: 482 S---------PAPTTVTFGSTD--SSTSTLHTLTPSTALSTIVSTSQ----VPIPSTHSS 526

Query: 434 QPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGA 493
             Q +P  P ++ ++    E   +  T+    +  +    +  + +S+ + IM  S + A
Sbjct: 527 TLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSA 586

Query: 494 IMTTKLVTT----PTGTQATYTRPTVSPSI-GRMAATPGAATYVKTTSGSIIT----VVP 544
            +T    TT    P+      T    S SI G  + +  A T   +TS S+ T    + P
Sbjct: 587 SITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITP 646

Query: 545 KSLATL------GGKII-----------------SSNIVSGTTTKITTIPMTSK----PN 577
            S  +L       G I                  S+   S  TT +T  P T++    P 
Sbjct: 647 FSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPT 706

Query: 578 VIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATR 628
            I +Q T         +  ++  +   NA       TVPT     + T+TR
Sbjct: 707 SISIQTTLTTYMDTSSMMPESESSISPNASSSTGTGTVPTN---TVFTSTR 754


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 171/906 (18%), Positives = 313/906 (34%), Gaps = 109/906 (12%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASN------VVVLPSGSTVYVKSVSCSDEDEK 200
            TSTT     +  P  + A   +PRP+ P ++       + +   +TV  K  + +++   
Sbjct: 104  TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 163

Query: 201  PRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVK 260
               + +T S+  +  + K   K + P SK +  P   +PK     +  A + P   +P  
Sbjct: 164  TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP---TPKAETTTKGPALTTPKEPTPT- 219

Query: 261  ITFTKPSTQT----TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
             T  +P++ T    T TT +        P+ T   +  +     A  T   P    A TT
Sbjct: 220  -TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP----APTT 274

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSP-IPNTVAVTAVVSSTPSVVMSTVAQGVSTSA 375
             K P   T  + +  +  S+ ++   P+P  P   A T      P+          +T  
Sbjct: 275  PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP---TTPK 331

Query: 376  IKMASTRLPSP----KSLVSAPTQILAQFPKQ-HQQSPKQQL-YQVQQQTQQQVAQPSPV 429
                +T+ P+P    +   +AP +     PK+    +PK+      ++ +     +P+P 
Sbjct: 332  EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391

Query: 430  SHQQQP--QQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT--ATLPTSSNSPI 485
            + +  P   + P P   K      +E       +    +   P P T     PT+   P 
Sbjct: 392  TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451

Query: 486  MVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545
                   A  TTK     T  +   T P  +        TP       TT   +    P+
Sbjct: 452  PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP-------TTPEKLAPTTPE 504

Query: 546  SLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLN 605
              A    + ++       T      P  + P             T    P          
Sbjct: 505  KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564

Query: 606  AGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK-IIPTKIVYGQQGKT 664
               ++T  T P G  P  L    P      T PK      +PA K + PT     ++  +
Sbjct: 565  TTPKETAPTTPKGTAPTTLKEPAP------TTPK------KPAPKELAPTTT---KEPTS 609

Query: 665  QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAE-AGNSSIQE------GKEEPQNYT 717
                KP P T + T  +       T   + A    +    ++++E       K  P+   
Sbjct: 610  TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 669

Query: 718  DSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIK 777
             +++    S+ S + +       A             E +PT   +   +  ++   T  
Sbjct: 670  PTTTKGPTSTTSDKPAPTTPKETAP--------TTPKEPAPTTPKKPAPTTPETPPPTTS 721

Query: 778  ALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAE-YI 836
             +     T     +   P + T +LS    P    +   +SP+ P +   ++    +  +
Sbjct: 722  EVSTPTTTKEPTTIHKSPDESTPELSAEPTP----KALENSPKEPGVPTTKTPAATKPEM 777

Query: 837  TTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQ-TATQTSVVVKSIPASSPG 895
            TT   D+ TE          +   + ++   T  +   +S+ TAT T V   +   ++P 
Sbjct: 778  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 837

Query: 896  AITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLS 955
             IT +    L+     TK  + + T E   +  +T  P+     R+  +++ + K QK +
Sbjct: 838  KITTLKTTTLAPKVTTTK--KTITTTEIMNKPEETAKPKD----RATNSKATTPKPQKPT 891

Query: 956  QPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPK 1015
            + P + T           TK+ +T              MP+  +R  K TP  ++     
Sbjct: 892  KAPKKPT----------STKKPKT--------------MPR--VRKPKTTPTPRKMTSTM 925

Query: 1016 PDVQHT 1021
            P++  T
Sbjct: 926  PELNPT 931



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 141/699 (20%), Positives = 228/699 (32%), Gaps = 76/699 (10%)

Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPS---GSIATVKSPRPASPASNVVVLPSGSTVYV 189
           PA T +KE    +      T T  P P+    +  T K P P +P       P       
Sbjct: 262 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK------ 315

Query: 190 KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249
                  E      +  T ++   P    + P    P     T P   +P      +  A
Sbjct: 316 -------EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPA 365

Query: 250 NSLPPHMSPVKITFTKPST--QTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            + P   +P       P+T  +   TTT+     T  P+ T   +  +     +  T   
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 425

Query: 308 PTSVI----ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVV 363
           P        A TT K P   T  + +  +     + ++T  P P T    A   +TP   
Sbjct: 426 PAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPA--PTTPKET 482

Query: 364 MSTVAQGVS-TSAIKMASTRLPSPKSLVS---APTQILAQFPKQHQQSPKQQLYQVQQQT 419
             T  + ++ T+  K+A T    P        APT      P   ++            T
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 542

Query: 420 QQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQ---VQPSKILPKPVTAT 476
            ++ A  +P        + P P   K T     +       ++     P K  PK +   
Sbjct: 543 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-- 600

Query: 477 LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536
            PT++  P        A       TTP GT  T  +     +    A T    T   T  
Sbjct: 601 -PTTTKEPTSTTCDKPA------PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 653

Query: 537 GSIITV----VPKSLA--TLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590
               T      PK LA  T  G   +++     TT   T P T K       K     T 
Sbjct: 654 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 713

Query: 591 IQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK 650
               P  + V+T        TI   P  + P +  +  P  K +   PK  G        
Sbjct: 714 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL--SAEPTPKALENSPKEPG-------- 763

Query: 651 IIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGK 710
            +PT        KT    KP+  T      +E+  +   ET   A ++ +   ++ ++  
Sbjct: 764 -VPTT-------KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 815

Query: 711 EEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQ 770
           E     T +  +ST    ++QD+ P    I + +      ++   T  TI   ++ ++ +
Sbjct: 816 ESKITATTTQVTST----TTQDTTP--FKITTLKTTTLAPKVT-TTKKTITTTEIMNKPE 868

Query: 771 SATSTIKALLELQQTTVKEKLESK-PRQPTIDLSQMAVP 808
                       + TT K +  +K P++PT       +P
Sbjct: 869 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP 907



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 125/588 (21%), Positives = 200/588 (34%), Gaps = 64/588 (10%)

Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKP----- 201
           T+T S PT+   PS +  T K P P +P       P                ++P     
Sbjct: 406 TTTKSAPTTPKEPSPT--TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463

Query: 202 RKRRRTNSSSSSPVVLKE----VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS 257
           +K   T     +P   KE     PK + P +     P +         + +A + P   +
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523

Query: 258 PV---KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS 314
           P    +   T P     NT  +        P+ T        +    A T    T   A 
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---AP 580

Query: 315 TTQKPPVVIT----ASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS------STPSVVM 364
           TT K P   T    A +    + +   +S++   P P T   TA  +      +TP    
Sbjct: 581 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 640

Query: 365 STVAQGVSTSAIK---MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421
            T  +G + + +K     + + P+PK L    T+           S K      ++    
Sbjct: 641 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKETAPT 695

Query: 422 QVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS 481
              +P+P + ++    +P  P   PT      S V   T   +P+ I   P  +T P  S
Sbjct: 696 TPKEPAPTTPKKPAPTTPETP--PPT-----TSEVSTPTTTKEPTTIHKSPDEST-PELS 747

Query: 482 NSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541
             P      N    + K    PT      T+P ++ +           T  +TT+ +   
Sbjct: 748 AEPTPKALEN----SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA--P 801

Query: 542 VVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT 601
            + K  AT   K   S I + TT   +T    + P  I   KTT     +         T
Sbjct: 802 KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 861

Query: 602 TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ 661
            ++N    K  +T     +     AT P  +     PK   ST +P  K +P      ++
Sbjct: 862 EIMN----KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP--KTMPRV----RK 911

Query: 662 GKTQVLIKPKPVTFQATVVS-EQTRQLVTETLQQASRVAEAGNSSIQE 708
            KT     P P    +T+     T ++    LQ  +R  +  NS + E
Sbjct: 912 PKT----TPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 955



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 61/308 (19%), Positives = 121/308 (39%), Gaps = 26/308 (8%)

Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPSG----SIATVKSPRPASPASNVVVLPSGSTVY 188
           P +   KE+   +    TST +  P P+     +  T K P P +P       P      
Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 719

Query: 189 VKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAV--------VPVSKTITVPVSGSPK 240
              VS     ++P    ++   S+  +  +  PKA+        VP +KT   P +  P+
Sbjct: 720 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT---PAATKPE 776

Query: 241 MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300
           M+   +          +P   T     T+ T TTT+K      + ++T V +  ++    
Sbjct: 777 MTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 836

Query: 301 AAVTKLVPTSVIASTTQKPPVVITA------SQSSLVSNSSSGSSSSTPSPIPNTVAVTA 354
             +T L  T++    T     + T        +++   + ++ S ++TP P   T A   
Sbjct: 837 FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 896

Query: 355 VVSSTPSVVMSTVAQGVSTSAIKMASTRLP--SPKSLVSAPTQILAQFPKQHQQSPKQQL 412
             S+     M  V +  +T   +  ++ +P  +P S ++   + + Q   +  Q+P  +L
Sbjct: 897 PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIA---EAMLQTTTRPNQTPNSKL 953

Query: 413 YQVQQQTQ 420
            +V  +++
Sbjct: 954 VEVNPKSE 961



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 94/456 (20%), Positives = 146/456 (32%), Gaps = 69/456 (15%)

Query: 101 PLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAE---TGSKEVVCYSYTSTTSTPTSTP 157
           P  P+    T    TA              P P E   T +KE      TSTT    +  
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP-----TSTTCDKPAPT 618

Query: 158 VPSGSIATV-KSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPV- 215
            P G+  T  K P P +P       P G+             +KP  +    +++  P  
Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 678

Query: 216 VLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTT 275
              + P    P     T P   +P             PP   P     + P+T    TT 
Sbjct: 679 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP---PTTSEVSTPTTTKEPTTI 735

Query: 276 QKVIIVTTSP-SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334
            K    +T   S+   P  L  S     V    PT+   + T KP +  TA   +   + 
Sbjct: 736 HKSPDESTPELSAEPTPKALENSPKEPGV----PTTKTPAAT-KPEMTTTAKDKTTERDL 790

Query: 335 SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPT 394
            +   ++T +P       T    +T S + +T  Q  ST+       ++ + K+   AP 
Sbjct: 791 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 850

Query: 395 QILAQ---FPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451
               +      +    P++      + T  +   P P    Q+P ++P  P         
Sbjct: 851 VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP----QKPTKAPKKP--------- 897

Query: 452 QESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYT 511
                   T   +P K +P+                          K  TTPT  + T T
Sbjct: 898 --------TSTKKP-KTMPR------------------------VRKPKTTPTPRKMTST 924

Query: 512 RPTVSPSIGRMAATPGAATYVKTTSGS-IITVVPKS 546
            P ++P+     A     T    T  S ++ V PKS
Sbjct: 925 MPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 960



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 170/908 (18%), Positives = 283/908 (31%), Gaps = 117/908 (12%)

Query: 281  VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340
            VTT  +ST   N +S S       K+     I      PP   T+ ++SL  N  +    
Sbjct: 99   VTTPDTSTTQHNKVSTS------PKITTAKPINPRPSLPPNSDTSKETSLTVNKET---- 148

Query: 341  STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQF 400
                       V    ++T +   ST  +  +TSA +  S    S K L      +    
Sbjct: 149  ----------TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 198

Query: 401  PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK--PTIQIKQESGVKI 458
            PK    +    L   ++ T     +P+  + ++     P P  IK  PT   K+ +    
Sbjct: 199  PKAETTTKGPALTTPKEPTPTTPKEPASTTPKE-----PTPTTIKSAPTTP-KEPAPTTT 252

Query: 459  ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPS 518
             +    P +  P       PT+   P    +   A  TTK   T     A  T    +P+
Sbjct: 253  KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312

Query: 519  IGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNV 578
              +  A         TT        PK  A              T     T P    P  
Sbjct: 313  TPKEPA--------PTTPKEPTPTTPKEPAPT------------TKEPAPTTPKEPAPTA 352

Query: 579  IVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRP---ITKMIV 635
                  T         P +   TT          +  PT  K A  T   P    TK   
Sbjct: 353  PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412

Query: 636  TQPK--GIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQ 693
            T PK     +T +PA    PT     ++       KP P T +    +       T T +
Sbjct: 413  TTPKEPSPTTTKEPA----PTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465

Query: 694  QASRVAE--AGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHE 751
             A    +  A  +  +     P+  T ++      +   + +      +A    +     
Sbjct: 466  PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 525

Query: 752  IAMETSPTIIYQDV-SSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQ 810
               E +PT       ++  + A +T K   E   TT KE   + P++      +   P  
Sbjct: 526  TPEEPAPTTPKAAAPNTPKEPAPTTPK---EPAPTTPKEPAPTTPKETAPTTPKGTAPTT 582

Query: 811  MTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLL 870
            + +    +P+ P+      + +A   T E T    +   P      + P  P +P  T  
Sbjct: 583  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPAPTTP 636

Query: 871  QHVA-QSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMD 929
            +  A  +   T  + + +  P +        +    +     T   +   T   E     
Sbjct: 637  KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 696

Query: 930  TLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQH 989
              +P      + A T  ++        PP   +++   T     TK+  TIH   D+   
Sbjct: 697  PKEPAPTTPKKPAPTTPET--------PPPTTSEVSTPT----TTKEPTTIHKSPDESTP 744

Query: 990  KLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAV 1049
            +L   P         TP   E +  +P V  T+ P   K     T               
Sbjct: 745  ELSAEP---------TPKALENSPKEPGVPTTKTPAATKPEMTTTAKD------------ 783

Query: 1050 KTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFE 1109
            KTT++            +   P+T  +   +   +   T    E  I    + VT  T +
Sbjct: 784  KTTER-----------DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832

Query: 1110 GRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVD 1169
               P  +T +   +  PK+T+   +I+  +   K   +   K     ++  T        
Sbjct: 833  DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 892

Query: 1170 PPKKALAT 1177
             PKK  +T
Sbjct: 893  APKKPTST 900



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 181/968 (18%), Positives = 296/968 (30%), Gaps = 116/968 (11%)

Query: 345  PIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404
            P P    V    S   +          ST+     ST   SPK   + P       P   
Sbjct: 78   PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST---SPKITTAKPINPRPSLPPNS 134

Query: 405  QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQ 464
              S +  L  V ++T  +  + +  + Q            K T  I++ S   +      
Sbjct: 135  DTSKETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL----AP 189

Query: 465  PSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAA 524
             SK+L KP          +P    ++ G  +TT    TPT  +   +     P+   + +
Sbjct: 190  TSKVLAKP----------TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 239

Query: 525  TPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKT 584
             P        T+       PK  A              TTTK    P T K       K 
Sbjct: 240  APTTPKEPAPTTTKSAPTTPKEPAP-------------TTTK-EPAPTTPKEPAPTTTKE 285

Query: 585  TGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK-PAILTATRPITKMIVTQPKGIGS 643
                TT      K+  TT          +  PT  K PA  T   P      T PK    
Sbjct: 286  PAPTTT------KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP----TTPKEPAP 335

Query: 644  TVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRV----A 699
            T +  A   P      ++       KP P T +    +       T T + +       A
Sbjct: 336  TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389

Query: 700  EAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIA----ME 755
                 S     +EP   T  S+ +T    S   ++             +  + A     E
Sbjct: 390  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449

Query: 756  TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEK 815
             +PT   +   + ++    T     E   TT KE   + P++ T    +   P       
Sbjct: 450  PAPTTPKEPAPTTTKKPAPTTPK--EPAPTTPKETAPTTPKKLTPTTPEKLAPT------ 501

Query: 816  RHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQ 875
              +PE P  A    E +A     E T    E   P      + P  P +P  T  +  A 
Sbjct: 502  --TPEKP--APTTPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAP 556

Query: 876  SQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELG---TEEGEVEEMDTLD 932
            +          K    ++P        +  +  T      +EL    T+E      D   
Sbjct: 557  TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 616

Query: 933  PQTGLFYRSALTQSQSAKQQKLSQP-------------PLEQTQLQVKTLQCFQTKQKQT 979
            P T         +  +    K   P             P   T  +    +   T  K  
Sbjct: 617  PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676

Query: 980  IHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQP 1039
                +D+     P  P+ +       P      +P P    T  P  + +   PT   +P
Sbjct: 677  TSTTSDK---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS-EVSTPTTTKEP 732

Query: 1040 PQTVVQVLAVKTTQQL---PKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPI 1096
              T +     ++T +L   P  +   N PK    P T     + P  +        E+ +
Sbjct: 733  --TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 790

Query: 1097 ITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLME 1156
             T   + T      ++  T T+ T  S +   T+ VTS +    +     +  LK + + 
Sbjct: 791  RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT--LKTTTLA 848

Query: 1157 AQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPST 1216
             ++ T          KK + T+ +  +                +TP+ QK  ++   P++
Sbjct: 849  PKVTTT---------KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 899

Query: 1217 VGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVE 1276
                 T  ++  P    T + M          E +P   I +A+ Q     + + N    
Sbjct: 900  TKKPKTMPRVRKPKTTPTPRKMT-----STMPELNPTSRIAEAMLQTTTRPNQTPN---- 950

Query: 1277 PSGLLELN 1284
             S L+E+N
Sbjct: 951  -SKLVEVN 957


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 171/906 (18%), Positives = 313/906 (34%), Gaps = 109/906 (12%)

Query: 147  TSTTSTPTSTPVPSGSIATVKSPRPASPASN------VVVLPSGSTVYVKSVSCSDEDEK 200
            TSTT     +  P  + A   +PRP+ P ++       + +   +TV  K  + +++   
Sbjct: 145  TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 204

Query: 201  PRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVK 260
               + +T S+  +  + K   K + P SK +  P   +PK     +  A + P   +P  
Sbjct: 205  TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP---TPKAETTTKGPALTTPKEPTPT- 260

Query: 261  ITFTKPSTQT----TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTT 316
             T  +P++ T    T TT +        P+ T   +  +     A  T   P    A TT
Sbjct: 261  -TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP----APTT 315

Query: 317  QKPPVVITASQSSLVSNSSSGSSSSTPSP-IPNTVAVTAVVSSTPSVVMSTVAQGVSTSA 375
             K P   T  + +  +  S+ ++   P+P  P   A T      P+          +T  
Sbjct: 316  PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP---TTPK 372

Query: 376  IKMASTRLPSP----KSLVSAPTQILAQFPKQ-HQQSPKQQL-YQVQQQTQQQVAQPSPV 429
                +T+ P+P    +   +AP +     PK+    +PK+      ++ +     +P+P 
Sbjct: 373  EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 432

Query: 430  SHQQQP--QQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT--ATLPTSSNSPI 485
            + +  P   + P P   K      +E       +    +   P P T     PT+   P 
Sbjct: 433  TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492

Query: 486  MVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPK 545
                   A  TTK     T  +   T P  +        TP       TT   +    P+
Sbjct: 493  PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP-------TTPEKLAPTTPE 545

Query: 546  SLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLN 605
              A    + ++       T      P  + P             T    P          
Sbjct: 546  KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605

Query: 606  AGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK-IIPTKIVYGQQGKT 664
               ++T  T P G  P  L    P      T PK      +PA K + PT     ++  +
Sbjct: 606  TTPKETAPTTPKGTAPTTLKEPAP------TTPK------KPAPKELAPTTT---KEPTS 650

Query: 665  QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAE-AGNSSIQE------GKEEPQNYT 717
                KP P T + T  +       T   + A    +    ++++E       K  P+   
Sbjct: 651  TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 710

Query: 718  DSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIK 777
             +++    S+ S + +       A             E +PT   +   +  ++   T  
Sbjct: 711  PTTTKGPTSTTSDKPAPTTPKETAP--------TTPKEPAPTTPKKPAPTTPETPPPTTS 762

Query: 778  ALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAE-YI 836
             +     T     +   P + T +LS    P    +   +SP+ P +   ++    +  +
Sbjct: 763  EVSTPTTTKEPTTIHKSPDESTPELSAEPTP----KALENSPKEPGVPTTKTPAATKPEM 818

Query: 837  TTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQ-TATQTSVVVKSIPASSPG 895
            TT   D+ TE          +   + ++   T  +   +S+ TAT T V   +   ++P 
Sbjct: 819  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 878

Query: 896  AITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLS 955
             IT +    L+     TK  + + T E   +  +T  P+     R+  +++ + K QK +
Sbjct: 879  KITTLKTTTLAPKVTTTK--KTITTTEIMNKPEETAKPKD----RATNSKATTPKPQKPT 932

Query: 956  QPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPK 1015
            + P + T           TK+ +T              MP+  +R  K TP  ++     
Sbjct: 933  KAPKKPT----------STKKPKT--------------MPR--VRKPKTTPTPRKMTSTM 966

Query: 1016 PDVQHT 1021
            P++  T
Sbjct: 967  PELNPT 972



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 141/699 (20%), Positives = 228/699 (32%), Gaps = 76/699 (10%)

Query: 133 PAETGSKEVVCYSYTSTTSTPTSTPVPS---GSIATVKSPRPASPASNVVVLPSGSTVYV 189
           PA T +KE    +      T T  P P+    +  T K P P +P       P       
Sbjct: 303 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK------ 356

Query: 190 KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249
                  E      +  T ++   P    + P    P     T P   +P      +  A
Sbjct: 357 -------EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPA 406

Query: 250 NSLPPHMSPVKITFTKPST--QTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307
            + P   +P       P+T  +   TTT+     T  P+ T   +  +     +  T   
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 466

Query: 308 PTSVI----ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVV 363
           P        A TT K P   T  + +  +     + ++T  P P T    A   +TP   
Sbjct: 467 PAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPA--PTTPKET 523

Query: 364 MSTVAQGVS-TSAIKMASTRLPSPKSLVS---APTQILAQFPKQHQQSPKQQLYQVQQQT 419
             T  + ++ T+  K+A T    P        APT      P   ++            T
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 583

Query: 420 QQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQ---VQPSKILPKPVTAT 476
            ++ A  +P        + P P   K T     +       ++     P K  PK +   
Sbjct: 584 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-- 641

Query: 477 LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTS 536
            PT++  P        A       TTP GT  T  +     +    A T    T   T  
Sbjct: 642 -PTTTKEPTSTTCDKPA------PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 694

Query: 537 GSIITV----VPKSLA--TLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590
               T      PK LA  T  G   +++     TT   T P T K       K     T 
Sbjct: 695 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 754

Query: 591 IQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAK 650
               P  + V+T        TI   P  + P +  +  P  K +   PK  G        
Sbjct: 755 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL--SAEPTPKALENSPKEPG-------- 804

Query: 651 IIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGK 710
            +PT        KT    KP+  T      +E+  +   ET   A ++ +   ++ ++  
Sbjct: 805 -VPTT-------KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 856

Query: 711 EEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQ 770
           E     T +  +ST    ++QD+ P    I + +      ++   T  TI   ++ ++ +
Sbjct: 857 ESKITATTTQVTST----TTQDTTP--FKITTLKTTTLAPKVT-TTKKTITTTEIMNKPE 909

Query: 771 SATSTIKALLELQQTTVKEKLESK-PRQPTIDLSQMAVP 808
                       + TT K +  +K P++PT       +P
Sbjct: 910 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP 948



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 125/588 (21%), Positives = 200/588 (34%), Gaps = 64/588 (10%)

Query: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKP----- 201
           T+T S PT+   PS +  T K P P +P       P                ++P     
Sbjct: 447 TTTKSAPTTPKEPSPT--TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504

Query: 202 RKRRRTNSSSSSPVVLKE----VPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS 257
           +K   T     +P   KE     PK + P +     P +         + +A + P   +
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564

Query: 258 PV---KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS 314
           P    +   T P     NT  +        P+ T        +    A T    T   A 
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---AP 621

Query: 315 TTQKPPVVIT----ASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS------STPSVVM 364
           TT K P   T    A +    + +   +S++   P P T   TA  +      +TP    
Sbjct: 622 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 681

Query: 365 STVAQGVSTSAIK---MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421
            T  +G + + +K     + + P+PK L    T+           S K      ++    
Sbjct: 682 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK-----GPTSTTSDKPAPTTPKETAPT 736

Query: 422 QVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSS 481
              +P+P + ++    +P  P   PT      S V   T   +P+ I   P  +T P  S
Sbjct: 737 TPKEPAPTTPKKPAPTTPETP--PPT-----TSEVSTPTTTKEPTTIHKSPDEST-PELS 788

Query: 482 NSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541
             P      N    + K    PT      T+P ++ +           T  +TT+ +   
Sbjct: 789 AEPTPKALEN----SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA--P 842

Query: 542 VVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT 601
            + K  AT   K   S I + TT   +T    + P  I   KTT     +         T
Sbjct: 843 KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 902

Query: 602 TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQ 661
            ++N    K  +T     +     AT P  +     PK   ST +P  K +P      ++
Sbjct: 903 EIMN----KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP--KTMPRV----RK 952

Query: 662 GKTQVLIKPKPVTFQATVVS-EQTRQLVTETLQQASRVAEAGNSSIQE 708
            KT     P P    +T+     T ++    LQ  +R  +  NS + E
Sbjct: 953 PKT----TPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 996



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 61/308 (19%), Positives = 121/308 (39%), Gaps = 26/308 (8%)

Query: 133  PAETGSKEVVCYSYTSTTSTPTSTPVPSG----SIATVKSPRPASPASNVVVLPSGSTVY 188
            P +   KE+   +    TST +  P P+     +  T K P P +P       P      
Sbjct: 701  PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 760

Query: 189  VKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAV--------VPVSKTITVPVSGSPK 240
               VS     ++P    ++   S+  +  +  PKA+        VP +KT   P +  P+
Sbjct: 761  TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT---PAATKPE 817

Query: 241  MSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY 300
            M+   +          +P   T     T+ T TTT+K      + ++T V +  ++    
Sbjct: 818  MTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 877

Query: 301  AAVTKLVPTSVIASTTQKPPVVITA------SQSSLVSNSSSGSSSSTPSPIPNTVAVTA 354
              +T L  T++    T     + T        +++   + ++ S ++TP P   T A   
Sbjct: 878  FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 937

Query: 355  VVSSTPSVVMSTVAQGVSTSAIKMASTRLP--SPKSLVSAPTQILAQFPKQHQQSPKQQL 412
              S+     M  V +  +T   +  ++ +P  +P S ++   + + Q   +  Q+P  +L
Sbjct: 938  PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIA---EAMLQTTTRPNQTPNSKL 994

Query: 413  YQVQQQTQ 420
             +V  +++
Sbjct: 995  VEVNPKSE 1002



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 94/456 (20%), Positives = 146/456 (32%), Gaps = 69/456 (15%)

Query: 101  PLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAE---TGSKEVVCYSYTSTTSTPTSTP 157
            P  P+    T    TA              P P E   T +KE      TSTT    +  
Sbjct: 605  PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP-----TSTTCDKPAPT 659

Query: 158  VPSGSIATV-KSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPV- 215
             P G+  T  K P P +P       P G+             +KP  +    +++  P  
Sbjct: 660  TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 719

Query: 216  VLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTT 275
               + P    P     T P   +P             PP   P     + P+T    TT 
Sbjct: 720  TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP---PTTSEVSTPTTTKEPTTI 776

Query: 276  QKVIIVTTSP-SSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNS 334
             K    +T   S+   P  L  S     V    PT+   + T KP +  TA   +   + 
Sbjct: 777  HKSPDESTPELSAEPTPKALENSPKEPGV----PTTKTPAAT-KPEMTTTAKDKTTERDL 831

Query: 335  SSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPT 394
             +   ++T +P       T    +T S + +T  Q  ST+       ++ + K+   AP 
Sbjct: 832  RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 891

Query: 395  QILAQ---FPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIK 451
                +      +    P++      + T  +   P P    Q+P ++P  P         
Sbjct: 892  VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP----QKPTKAPKKP--------- 938

Query: 452  QESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYT 511
                    T   +P K +P+                          K  TTPT  + T T
Sbjct: 939  --------TSTKKP-KTMPR------------------------VRKPKTTPTPRKMTST 965

Query: 512  RPTVSPSIGRMAATPGAATYVKTTSGS-IITVVPKS 546
             P ++P+     A     T    T  S ++ V PKS
Sbjct: 966  MPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1001



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 170/908 (18%), Positives = 283/908 (31%), Gaps = 117/908 (12%)

Query: 281  VTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSS 340
            VTT  +ST   N +S S       K+     I      PP   T+ ++SL  N  +    
Sbjct: 140  VTTPDTSTTQHNKVSTS------PKITTAKPINPRPSLPPNSDTSKETSLTVNKET---- 189

Query: 341  STPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQF 400
                       V    ++T +   ST  +  +TSA +  S    S K L      +    
Sbjct: 190  ----------TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 239

Query: 401  PKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIK--PTIQIKQESGVKI 458
            PK    +    L   ++ T     +P+  + ++     P P  IK  PT   K+ +    
Sbjct: 240  PKAETTTKGPALTTPKEPTPTTPKEPASTTPKE-----PTPTTIKSAPTTP-KEPAPTTT 293

Query: 459  ITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPS 518
             +    P +  P       PT+   P    +   A  TTK   T     A  T    +P+
Sbjct: 294  KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353

Query: 519  IGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNV 578
              +  A         TT        PK  A              T     T P    P  
Sbjct: 354  TPKEPA--------PTTPKEPTPTTPKEPAPT------------TKEPAPTTPKEPAPTA 393

Query: 579  IVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRP---ITKMIV 635
                  T         P +   TT          +  PT  K A  T   P    TK   
Sbjct: 394  PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453

Query: 636  TQPK--GIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQ 693
            T PK     +T +PA    PT     ++       KP P T +    +       T T +
Sbjct: 454  TTPKEPSPTTTKEPA----PTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506

Query: 694  QASRVAE--AGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHE 751
             A    +  A  +  +     P+  T ++      +   + +      +A    +     
Sbjct: 507  PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 566

Query: 752  IAMETSPTIIYQDV-SSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQ 810
               E +PT       ++  + A +T K   E   TT KE   + P++      +   P  
Sbjct: 567  TPEEPAPTTPKAAAPNTPKEPAPTTPK---EPAPTTPKEPAPTTPKETAPTTPKGTAPTT 623

Query: 811  MTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLL 870
            + +    +P+ P+      + +A   T E T    +   P      + P  P +P  T  
Sbjct: 624  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPAPTTP 677

Query: 871  QHVA-QSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMD 929
            +  A  +   T  + + +  P +        +    +     T   +   T   E     
Sbjct: 678  KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 737

Query: 930  TLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQH 989
              +P      + A T  ++        PP   +++   T     TK+  TIH   D+   
Sbjct: 738  PKEPAPTTPKKPAPTTPET--------PPPTTSEVSTPT----TTKEPTTIHKSPDESTP 785

Query: 990  KLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAV 1049
            +L   P         TP   E +  +P V  T+ P   K     T               
Sbjct: 786  ELSAEP---------TPKALENSPKEPGVPTTKTPAATKPEMTTTAKD------------ 824

Query: 1050 KTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFE 1109
            KTT++            +   P+T  +   +   +   T    E  I    + VT  T +
Sbjct: 825  KTTER-----------DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873

Query: 1110 GRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVD 1169
               P  +T +   +  PK+T+   +I+  +   K   +   K     ++  T        
Sbjct: 874  DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 933

Query: 1170 PPKKALAT 1177
             PKK  +T
Sbjct: 934  APKKPTST 941



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 181/968 (18%), Positives = 296/968 (30%), Gaps = 116/968 (11%)

Query: 345  PIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404
            P P    V    S   +          ST+     ST   SPK   + P       P   
Sbjct: 119  PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST---SPKITTAKPINPRPSLPPNS 175

Query: 405  QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQ 464
              S +  L  V ++T  +  + +  + Q            K T  I++ S   +      
Sbjct: 176  DTSKETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL----AP 230

Query: 465  PSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAA 524
             SK+L KP          +P    ++ G  +TT    TPT  +   +     P+   + +
Sbjct: 231  TSKVLAKP----------TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 280

Query: 525  TPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKT 584
             P        T+       PK  A              TTTK    P T K       K 
Sbjct: 281  APTTPKEPAPTTTKSAPTTPKEPAP-------------TTTK-EPAPTTPKEPAPTTTKE 326

Query: 585  TGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAK-PAILTATRPITKMIVTQPKGIGS 643
                TT      K+  TT          +  PT  K PA  T   P      T PK    
Sbjct: 327  PAPTTT------KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP----TTPKEPAP 376

Query: 644  TVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRV----A 699
            T +  A   P      ++       KP P T +    +       T T + +       A
Sbjct: 377  TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430

Query: 700  EAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIA----ME 755
                 S     +EP   T  S+ +T    S   ++             +  + A     E
Sbjct: 431  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490

Query: 756  TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEK 815
             +PT   +   + ++    T     E   TT KE   + P++ T    +   P       
Sbjct: 491  PAPTTPKEPAPTTTKKPAPTTPK--EPAPTTPKETAPTTPKKLTPTTPEKLAPT------ 542

Query: 816  RHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQ 875
              +PE P  A    E +A     E T    E   P      + P  P +P  T  +  A 
Sbjct: 543  --TPEKP--APTTPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAP 597

Query: 876  SQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELG---TEEGEVEEMDTLD 932
            +          K    ++P        +  +  T      +EL    T+E      D   
Sbjct: 598  TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 657

Query: 933  PQTGLFYRSALTQSQSAKQQKLSQP-------------PLEQTQLQVKTLQCFQTKQKQT 979
            P T         +  +    K   P             P   T  +    +   T  K  
Sbjct: 658  PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717

Query: 980  IHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQP 1039
                +D+     P  P+ +       P      +P P    T  P  + +   PT   +P
Sbjct: 718  TSTTSDK---PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS-EVSTPTTTKEP 773

Query: 1040 PQTVVQVLAVKTTQQL---PKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPI 1096
              T +     ++T +L   P  +   N PK    P T     + P  +        E+ +
Sbjct: 774  --TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 831

Query: 1097 ITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLME 1156
             T   + T      ++  T T+ T  S +   T+ VTS +    +     +  LK + + 
Sbjct: 832  RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT--LKTTTLA 889

Query: 1157 AQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPST 1216
             ++ T          KK + T+ +  +                +TP+ QK  ++   P++
Sbjct: 890  PKVTTT---------KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 940

Query: 1217 VGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVE 1276
                 T  ++  P    T + M          E +P   I +A+ Q     + + N    
Sbjct: 941  TKKPKTMPRVRKPKTTPTPRKMT-----STMPELNPTSRIAEAMLQTTTRPNQTPN---- 991

Query: 1277 PSGLLELN 1284
             S L+E+N
Sbjct: 992  -SKLVEVN 998


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 269/1257 (21%), Positives = 418/1257 (33%), Gaps = 192/1257 (15%)

Query: 85   GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCY 144
            GP S++  S  G     L+P            N  A+  ++  AS PV + TGS      
Sbjct: 1772 GPESTTFHSSPGSTETTLLPD-----------NTTASGLLE--ASTPVHSSTGSPHTTLS 1818

Query: 145  SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPS---GSTVYVKSVSCSDEDEKP 201
               STT    ST   S   +    P P +  S  V L +   GS     +   S      
Sbjct: 1819 PAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 1878

Query: 202  RKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGS---------------PKMSNIMQ 246
             +   + +  SSPV     P    P   T +  V  S               P+ S    
Sbjct: 1879 GRSEESTTVHSSPVATATTPS---PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASG 1935

Query: 247  SIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNI------------- 293
                S   H S      + PS  TT+   ++     +SP ST   +              
Sbjct: 1936 RSEESRTSHSSTTHTISSPPS--TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 1993

Query: 294  -LSKSHNYAAVTKLVP----TSVIASTTQKPPVVITASQSSLVSNSSS----GSSSSTPS 344
              S S   A  T ++P    TSV+   +   P+   + +++ +  S++       S+T  
Sbjct: 1994 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH 2053

Query: 345  PIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQH 404
              P + A T   +ST S   S V++  +TS  +  ST   +     + P           
Sbjct: 2054 SSPRSPATTLSPASTTS---SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 2110

Query: 405  QQSPKQQLYQVQQQTQQQVAQPSPVSHQQQ-PQQSPLPPGIKPTIQIKQESGVKIITQQV 463
                          T    +Q S  SH       + L PG    +   QES     +   
Sbjct: 2111 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS 2170

Query: 464  QPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTG-----------TQATYTR 512
              + + P   T++    +++   V SS G+  TT    + T            T    T 
Sbjct: 2171 THTTLFPDSTTSSGIVEAST--RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 2228

Query: 513  PTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLG----GKIISSNIVSGTTTKIT 568
             T SP     A    + TY ++   +  T  P S  T G      I  S+  +  TT  +
Sbjct: 2229 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2288

Query: 569  TIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE--KTIQTVPTGAKPAILTA 626
                TS        + +   T I  LPG      L  A      + ++  T   PA +T+
Sbjct: 2289 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTS 2348

Query: 627  TRPITKMIV--TQPKGIGSTVQPAAKIIP------TKIVYGQQGKTQVLIKPK------- 671
                 +     +QP    STV PA+   P      T +     G T+  + P+       
Sbjct: 2349 LGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVR 2408

Query: 672  ---PVTFQATVVSEQ----TRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724
               P TF +   S      T    T  L + S       +S Q G        D    ST
Sbjct: 2409 GEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEEST 2468

Query: 725  ESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ 784
                SS  +   +    S     +   +  E++P+ +     S S + T+T+        
Sbjct: 2469 TFPSSSGSTGTTLSPARS-----TTSGLVGESTPSRL-----SPSSTETTTL-------- 2510

Query: 785  TTVKEKLESKPRQPTI-DLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDE 843
                      P  PT   LS+ +     +     +  SP  A   S  V+E  +T  +  
Sbjct: 2511 ----------PGSPTTPSLSEKSTTFYTSPRSPDATLSP--ATTTSSGVSEESSTSHSQP 2558

Query: 844  GT--EVAFP-------LLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPAS-- 892
            G+    AFP       L     +    P     TLL     +   +Q S    S P S  
Sbjct: 2559 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 2618

Query: 893  ---SPGAITHIM--QQALSSHTA----FTKHSEELGTEEGEVEEMDTLDPQTGLFYRSAL 943
               SPG+ T +   Q++ + H++     T    +  T  G VE    +   TG   R+ L
Sbjct: 2619 TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTL 2677

Query: 944  TQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLP-QMPQLSIRHQ 1002
            + + S       +    QT     T          T  ++     H+ P   P       
Sbjct: 2678 SPASSTSPGLQGESTTFQTH-PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 2736

Query: 1003 KLTPLQQEQA---QPKPDVQHT----QHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQL 1055
              T    E++      PD   T     H   +   +  T    P  T +  L   TT   
Sbjct: 2737 STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT--T 2794

Query: 1056 PKLQQAPNQPKIYVQPQTPQSQMSLPAS------SEKQTASQVEQPIITQGSSVTKITFE 1109
            P L +A      Y  P++P + +S PAS       E+ T S+  QP    GS+ + ++  
Sbjct: 2795 PGLSEA--STTFYSSPRSPTTTLS-PASMTSLGVGEESTTSR-SQP----GSTHSTVSPA 2846

Query: 1110 GRQPPTVTK--ITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMI 1167
                P +++   T  SS P  T   T++ P   S  T+V      +       T+     
Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTE--TTVFP--RSTTTSVRGEEPTTFHSRPASTHTTLFT 2902

Query: 1168 VDPPKKALATSMLTGEAGSLP-STHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTT 1223
             D       TS LT E+ + P S      G+  +        ES + PS+ GS+ TT
Sbjct: 2903 EDS-----TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT 2954



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 268/1277 (20%), Positives = 432/1277 (33%), Gaps = 151/1277 (11%)

Query: 128  ASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTV 187
            AS PV + TGS        +STT     T   S   +   SP P+   S  V L   ST 
Sbjct: 391  ASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKL---STT 447

Query: 188  YVKSVSCSDEDEKPRKRRRTNSSSSSPVV---LKEVPKAVVPVSKTITVPVSGSPKMSNI 244
            Y  S         P     T+ S+SS  +    +  P    PV+   T P + S    ++
Sbjct: 448  YHSS---------PSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHV 498

Query: 245  MQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNIL-SKSHNYAAV 303
             +S A     H SP        STQT +          +  S+TF  +   +KS   +  
Sbjct: 499  EESTAY----HRSP-------GSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTT 547

Query: 304  TKLVPTSVIAS-----TT--QKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVV 356
              L  TS  +S     TT  +    +   S+ S  S+SS  + ++T  P  +T +V  V 
Sbjct: 548  AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSV-LVG 606

Query: 357  SSTPSVVM-----------STVAQGVS-TSAIKMASTRLPSPKSLVSAPTQ--ILAQFPK 402
             STPS +            ST   G+S  S    +S R P    L ++ T   +  +   
Sbjct: 607  DSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTT 666

Query: 403  QHQQSPKQQLYQVQ-QQTQQQVAQPSPVSHQQQ-PQQSPLPPGIKPTIQIKQESGVKIIT 460
             H +             T   ++Q S  SH    P  + L PG      +  E       
Sbjct: 667  SHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSR 726

Query: 461  QQVQPSKILPKPVTAT--------LPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATY-T 511
                 + +LP   TA+        + +S+ SP   +S  G+       TT  G   T+ +
Sbjct: 727  PGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGS-------TTRQGESTTFHS 779

Query: 512  RPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIP 571
             P+   +      T  A     TTS    + +P +   +  +  +S +V  +TT  ++  
Sbjct: 780  WPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT--HISARSTTSGLVEESTTYHSSPG 837

Query: 572  MTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTV--PTG--AKPAILTAT 627
             T   +      T+G+G   +     +  T  +++    T   V  PT   + P   TAT
Sbjct: 838  STQTMHFPESDTTSGRGE--ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG-STAT 894

Query: 628  RPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQL 687
                    T  +   ST   +++     IV   +  T VL+       ++T     +  +
Sbjct: 895  THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG------ESTTSPISSGSM 948

Query: 688  VTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDW 747
             T  L  ++        S           T  S +ST SS  S++S        SR +  
Sbjct: 949  ETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEES------TTSRSRPG 1002

Query: 748  SEHEIAMETSPTI--IYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQM 805
            S H  A   S T   + +  ++   S  ST   LL    TT     ES     +   +  
Sbjct: 1003 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDT 1062

Query: 806  AVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQP 865
            A+    T       ES +                 T  G   A   + S    P+    P
Sbjct: 1063 ALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 1122

Query: 866  QRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH----TAFTKHSEELGTE 921
              +    +    TA QT         S P   T  ++++ + H    +  T H     T 
Sbjct: 1123 ASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT 1182

Query: 922  EGEVEE---MDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQ 978
             G  E+     +    +G    SA + +    +   S+  +     ++ TL    T    
Sbjct: 1183 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR--ISPGSTEITTLPGSTTTPGL 1240

Query: 979  TIHLQADQLQHKLPQMPQLSIRHQKLTPL-QQEQAQPKPDVQHTQHPMVAKDRQLPTLMA 1037
            +   +A    +  P+ P  ++    +T L   E++        + H  V+     P    
Sbjct: 1241 S---EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS-----PASTT 1292

Query: 1038 QPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPAS------SEKQTASQ 1091
             P  +        +++   +    P+     V  + P +  S PAS      +E  T S 
Sbjct: 1293 TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSG 1352

Query: 1092 VEQ--------PIITQ-GSSVTKITFEGRQPPTVTKITGGSSVPKLT------------S 1130
            + +        P  TQ G   T  T +  +  T    + GS+  KL+            S
Sbjct: 1353 LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGES 1412

Query: 1131 PVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPP-KKALATSMLTGEAGSLP- 1188
              + +SP      T        SL E            D     A  TS    E  S   
Sbjct: 1413 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH 1472

Query: 1189 ----STHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRI--QN 1242
                STH       +ST      +E  +S S+ GS+  T         + GQ       +
Sbjct: 1473 SQPGSTH--TTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSS 1530

Query: 1243 VGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDI 1302
             G  +    P + I   + + + P HSS+  +      L   + TS  L +E T  +   
Sbjct: 1531 PGDTETTLLPDDTITSGLVEASTPTHSSTGSL---HTTLTPASSTSAGLQEESTTFQSWP 1587

Query: 1303 DSSTEDGTEPSPSQSSA 1319
             SS    T PSP  ++A
Sbjct: 1588 SSS---DTTPSPPGTTA 1601



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 267/1364 (19%), Positives = 450/1364 (32%), Gaps = 222/1364 (16%)

Query: 81   HNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAF---TVTANAVANAAIQHNASLPVPAETG 137
            H    P S++   +E        P   P T F   + T+     + I H++    P  +G
Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS----PDASG 2757

Query: 138  SKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDE 197
            +     +S TS     T++ +  GS             + +  LP  +T    S + +  
Sbjct: 2758 TTPSSAHSTTSGRGESTTSRISPGS-------------TEITTLPGSTTTPGLSEASTTF 2804

Query: 198  DEKPRKRRRTNSSSSSP---VVLKEVPKAVVPVS--KTITVPVSGSPKMSNIMQSIANSL 252
               PR    T S +S     V  +       P S   T++   + +P +S    ++ +S 
Sbjct: 2805 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2864

Query: 253  PPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK---LVPT 309
            P        T   P + TT+   ++     + P+ST    + ++    + +T+     P 
Sbjct: 2865 PGSTE----TTVFPRSTTTSVRGEEPTTFHSRPASTHT-TLFTEDSTTSGLTEESTAFPG 2919

Query: 310  SVIASTTQKPPVVITAS--QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSS----TPSVV 363
            S  ++ T  P  + TA   + S    SSSGS+ +T SP  +T +     S+    +PS  
Sbjct: 2920 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2979

Query: 364  MSTVAQGVST--SAIKMASTRLPSPKS-------LVSAPTQILAQFPKQHQQSPKQQLYQ 414
             +T   G  T  S  + ++T   SP+S         +  + +  +    H Q        
Sbjct: 2980 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 3039

Query: 415  VQQQTQQQ-VAQPSPVSHQQQ-PQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKP 472
                T    ++Q    SH  Q   ++ L PG      + Q+S     +     + +LP  
Sbjct: 3040 FPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD 3099

Query: 473  ------VTATLPTSS-----NSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGR 521
                  V A+ PT S     ++ +   SS  A +  +  T  +   ++ T P  SP    
Sbjct: 3100 TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP--SPPGTT 3157

Query: 522  MAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGT-TTKITTIPMTSKPNVIV 580
             A    + TY    S +  T    S  TLG    S+ + S    T     P  S  +V+V
Sbjct: 3158 AAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLV 3217

Query: 581  VQKTTGK----GTTIQGLPGKNVVTTLLNAGGE--KTIQTVPTGAKPAILTATRPITKMI 634
             + TT       T    LPG      L         + ++  T   PA  T++    +  
Sbjct: 3218 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 3277

Query: 635  V--TQPKGIGSTVQPAAKIIP-----TKIVYGQQGKTQVLIK----------PKPVTFQA 677
               ++P    +T  P +  +P     +   +   G T   +           P+  TF +
Sbjct: 3278 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 3337

Query: 678  TVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVV 737
               S +T  L   T   AS + EA ++ +      P      + S+T   +S        
Sbjct: 3338 GPGSTETTLLPDNT--TASGLLEA-STPVHSSTGSPHTTLSPAGSTTRQGES-------- 3386

Query: 738  HVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQ 797
                +  Q W   +      PT               T  A +EL  T+      S    
Sbjct: 3387 ----TTFQSWPNSKDTTPAPPT---------------TTSAFVELSTTS----HGSPSST 3423

Query: 798  PTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRS 857
            PT   S  +  +  ++E      SP +A   +   A   T+   +E T            
Sbjct: 3424 PTTHFSASSTTLGRSEESTTVHSSP-VATATTPSPARSTTSGLVEEST------------ 3470

Query: 858  QPQQPSQPQRTLLQHVAQSQTA-----------TQTSVVVKSIPASSPGAITHIMQQALS 906
                 S P  T   H  +S T            + T+  + S P+++   +        S
Sbjct: 3471 --TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS 3528

Query: 907  SHTAFTKHSEELGTEEGEVEE---MDTLDPQTGLFYRSALTQSQ----SAKQQKLSQPPL 959
              +  T H  +  T  G  EE     +    TG     A + +      +    +S   +
Sbjct: 3529 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 3588

Query: 960  EQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPL----QQEQAQPK 1015
            E T L   T     +++  T         H  P+ P  ++     T      +   +  +
Sbjct: 3589 ETTALPGSTTTPGLSEKSTTF--------HSSPRSPATTLSPASTTSSGVSEESTTSHSR 3640

Query: 1016 PDVQHT-----QHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQ 1070
            P   HT             R   T  + P  T   +L   TT      Q++         
Sbjct: 3641 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS-GSSQESTTSHSSSGS 3699

Query: 1071 PQTPQSQMSLPASSEKQTASQV-EQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLT 1129
              T  S  S  A S  Q ++     P  T  +     T         T++   +  P+ T
Sbjct: 3700 TDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 3759

Query: 1130 -SPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALA----TSMLTGEA 1184
             SP +S SP    E TA            Q      H    PP  A A    ++      
Sbjct: 3760 LSPASSTSPGLQGESTAF-----------QTHPASTHTTPSPPSTATAPVEESTTYHRSP 3808

Query: 1185 GSLPSTHMVVAG----------MANSTPQQQKCRESCSSPSTVG-SSLTTRKIDPPAVPA 1233
            GS P+TH   +           + +S+P       S +  +T G    TT +I P +   
Sbjct: 3809 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 3868

Query: 1234 TGQFMRIQNVGQKKAEE-------------SPAEIIIQAIPQYAIPCHS---SSNVVVEP 1277
            T         G  +A               SPA +    + + +    S   S++  V P
Sbjct: 3869 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP 3928

Query: 1278 SGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAER 1321
            +      + T+  L +E T +      STE    P  + +S  R
Sbjct: 3929 A------STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRR 3966



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 273/1345 (20%), Positives = 467/1345 (34%), Gaps = 198/1345 (14%)

Query: 85   GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCY 144
            GP S++  S  G     L+P            N  A+  ++  AS PV + TGS      
Sbjct: 3329 GPESTTFHSGPGSTETTLLPD-----------NTTASGLLE--ASTPVHSSTGSPHTTLS 3375

Query: 145  SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204
               STT    ST   S   +   +P P +  S  V L + S               P   
Sbjct: 3376 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTS------------HGSPSST 3423

Query: 205  RRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFT 264
              T+ S+SS  + +      V  S  +    + SP  S     +  S   H SP      
Sbjct: 3424 PTTHFSASSTTLGRSEESTTVH-SSPVATATTPSPARSTTSGLVEESTTYHSSP------ 3476

Query: 265  KPSTQT-----TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS----- 314
              STQT     ++TT+ +    TTS SST   + +S + +  +     PTS  +S     
Sbjct: 3477 -GSTQTMHFPESDTTSGRGEESTTSHSST--THTISSAPSTTSALVEEPTSYHSSPGSTA 3533

Query: 315  TTQKPPVVITA--SQSSLVSNSSSGSSSSTPSPIPNTVAV------TAVVSS----TPSV 362
            TT  P    T+  S+ S  S+SS  ++ +   P  +T +V      T+ +SS    T ++
Sbjct: 3534 TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL 3593

Query: 363  VMSTVAQGVSTSAIKM-ASTRLP----SPKSLVSA------------------------- 392
              ST   G+S  +    +S R P    SP S  S+                         
Sbjct: 3594 PGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDST 3653

Query: 393  PTQILAQFPKQHQQSP--KQQLYQVQQQTQQQVAQPSPVSHQQQ-PQQSPLPPGIKPTIQ 449
             T  L++       SP            T    +Q S  SH       + L PG    + 
Sbjct: 3654 TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALS 3713

Query: 450  IKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTG---- 505
              QES     +     + + P   T++    +++   V SS G+  TT    + T     
Sbjct: 3714 FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAST--RVHSSTGSPRTTLSPASSTSPGLQ 3771

Query: 506  -------TQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLG----GKI 554
                   T    T  T SP     A    + TY ++   +  T  P S  T G      I
Sbjct: 3772 GESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 3831

Query: 555  ISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGE--KTI 612
              S+  +  TT  +    TS        + +   T I  LPG      L  A      + 
Sbjct: 3832 FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP 3891

Query: 613  QTVPTGAKPAILTATRPITKMIV--TQPKGIGSTVQPAAKIIP------TKIVYGQQGKT 664
            ++  T   PA +T+     +     +QP    STV PA+   P      T +     G T
Sbjct: 3892 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGST 3951

Query: 665  QVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSST 724
            +  + P+     +T  S +  +  T   + AS      ++++          T+ S++  
Sbjct: 3952 ETTVFPR-----STTTSVRREEPTTFHSRPAST-----HTTLFTEDSTTSGLTEESTAFP 4001

Query: 725  ESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQ 784
             S  S+Q   P     A   ++ +    +  ++ T +    S+ S     +  + L    
Sbjct: 4002 GSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS-PS 4060

Query: 785  TTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEG 844
            +T    L   P  P+  LS+ +     +     +  SP  A   S  V+E  +T  +  G
Sbjct: 4061 STETTTLPGSPTTPS--LSEKSTTFYTSPRSPDATLSP--ATTTSSGVSEESSTSHSQPG 4116

Query: 845  T--EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQ 902
            +    AFP   +     Q+P+            SQ +T+ ++   S  ASS G      Q
Sbjct: 4117 STHTTAFPDSTTTSGLSQEPTTSH--------SSQGSTEATLSPGSTTASSLG------Q 4162

Query: 903  QALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQT 962
            Q+ + H++        G  E  +   DT+   +GL   S  T S +        P    +
Sbjct: 4163 QSTTFHSS-------PGDTETTLLPDDTI--TSGLVEASTPTHSSTGSLHTTLTPASSTS 4213

Query: 963  ---QLQVKTLQCFQTKQKQT--------IHLQADQLQHKLPQMPQLSIRHQKLTPL--QQ 1009
               Q +  T Q + +    T        + ++     H  P     +      T L   +
Sbjct: 4214 TGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 4273

Query: 1010 EQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPK--- 1066
            E          T   +         L+ +P  + +   + +TT        A    K   
Sbjct: 4274 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 4333

Query: 1067 IYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGS--S 1124
             Y  P++P + +S PAS+     S+      ++  S+    F     P+ T + G S  S
Sbjct: 4334 FYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPGSMHTTAF-----PSSTTMPGVSQES 4387

Query: 1125 VPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEA 1184
                +SP ++ + +     TA S   + +   +   +    ++ D    +      T   
Sbjct: 4388 TASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVH 4447

Query: 1185 GSLPSTHMVVAGMANSTPQQQ--------KCRESCSSPSTVGSS---LTTRKIDPPAVPA 1233
             S  S H  ++   ++T Q +          +++  +P T  S+   L+T     P+   
Sbjct: 4448 SSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTP 4507

Query: 1234 TGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDD 1293
            T  F        +  E +       A      P  S+++ +VE S     +  ++Q +  
Sbjct: 4508 TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHF 4567

Query: 1294 EETAMEQDIDSSTEDGTEPSPSQSS 1318
             E+      ++++  G E + S SS
Sbjct: 4568 PES------NTTSGRGEESTTSHSS 4586



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 152/683 (22%), Positives = 247/683 (36%), Gaps = 106/683 (15%)

Query: 85   GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCY 144
            GP S++  S  G     L+P            N  A+  ++  AS PV + TGS      
Sbjct: 4412 GPESTTFHSSPGSTETTLLPD-----------NTTASGLLE--ASTPVHSSTGSPHTTLS 4458

Query: 145  SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204
               STT    ST   S   +   +P P +  S  V L + S               P   
Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTS------------HGSPSST 4506

Query: 205  RRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFT 264
              T+ S+SS  + +      V  S  +    + SP  S     +  S   H SP      
Sbjct: 4507 PTTHFSASSTTLGRSEESTTVH-SSPVATATTPSPARSTTSGLVEESTTYHSSP------ 4559

Query: 265  KPSTQT-----TNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS----- 314
              STQT     +NTT+ +    TTS SST   + +S + +  +     PTS  +S     
Sbjct: 4560 -GSTQTMHFPESNTTSGRGEESTTSHSST--THTISSAPSTTSALVEEPTSYHSSPGSTA 4616

Query: 315  TTQKPPVVITA--SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVS 372
            TT  P    T+  S+ S  S+SS  ++ +   P  +T +V    S+T     S ++ G  
Sbjct: 4617 TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT-----SPISSGSM 4671

Query: 373  TSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQ 432
             +     ST  P      +      +  P  H  +    L + ++ T       SPV+  
Sbjct: 4672 ETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEEST---TVHSSPVATA 4728

Query: 433  QQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTAT-----LPTSSNSPIMV 487
              P      P    T  + +ES     +     +   P+  TA+       TS +S    
Sbjct: 4729 TTPS-----PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 4783

Query: 488  VSSNGAIMTTKLVTTPT------GTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIIT 541
            +SS  +  T+ LV  PT      G+ AT   P  S + GR   +  + +   T     IT
Sbjct: 4784 ISSPPS-TTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNG---IT 4839

Query: 542  VVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVT 601
             +P    T G    S+       +  TT+  T+         TT         PG +  +
Sbjct: 4840 PLPAHFTTSGRIAESTTFYISPGSMETTLASTA---------TT---------PGLSAKS 4881

Query: 602  TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKII-----PTKI 656
            T+L +      QT+   +  +   +  P +  + +Q +   +T  PA+         +  
Sbjct: 4882 TILYSSSRSPDQTLSPASMTSSSISGEPTS--LYSQAESTHTTAFPASTTTSGLSQESTT 4939

Query: 657  VYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQ-EGKEEPQN 715
             + + G T+  + P  +T      S   ++  T   Q  S ++    +S    G  E   
Sbjct: 4940 FHSKPGSTETTLSPGSIT-----TSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEEST 4994

Query: 716  YTDSSSSSTESSQSSQDSQPVVH 738
               SS  STE++  S  +   +H
Sbjct: 4995 TFYSSPGSTETTAFSHSNTMSIH 5017



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 261/1326 (19%), Positives = 429/1326 (32%), Gaps = 210/1326 (15%)

Query: 73   DERLTTIAHNMSGPN--SSSEWSIEGRRLVPLMPRLVPQTAFTVTANAV-ANAAIQHNAS 129
            D  L   +   SGP+  S++  S  G     L P      +F   +    +N    H   
Sbjct: 1033 DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 1092

Query: 130  LPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYV 189
             P    +           S+T +P +T  P+ S  T    +  S A       + +T   
Sbjct: 1093 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS--TSPGLQGESTAFQTHPASTHTTPSP 1150

Query: 190  KSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIA 249
             S + +  +E     R   S+          P    P S T     SG  + S I  S  
Sbjct: 1151 PSTATAPVEESTTYHRSPGST----------PTTHFPASST----TSGHSEKSTIFHSSP 1196

Query: 250  NSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNY-----AAVT 304
            ++     S    T +     TT+  +     +TT P ST  P +   S  +     +  T
Sbjct: 1197 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 1256

Query: 305  KLVPTSVIA------STTQK----------PPVVIT----ASQSSLVSNSSSGSSSSTPS 344
             L P S+ +      STT +           P   T    + +S+ V +SS GS+ +T  
Sbjct: 1257 TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVF 1316

Query: 345  PIPNTVAV-----TAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPS---------PKSLV 390
            P   T +V     T   S   S   +   +  +TS +   ST  P          P +L 
Sbjct: 1317 PHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLT 1376

Query: 391  SAPT-QILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQ 449
            +A   +    FP     S   +L   +  T   V + +P        ++   PG  PT  
Sbjct: 1377 TADLGEESTTFPSS-SGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG-SPTTP 1434

Query: 450  IKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTT---------KLV 500
               E      T    P   L  P T T    S       S  G+  TT          L 
Sbjct: 1435 SLSEKSTTFYTSPRSPDATL-SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLS 1493

Query: 501  TTPTGTQATY--TRPTVSP------SIGRMAAT----PG------------------AAT 530
              PT + ++   T  T+SP      S+G+ + T    PG                  A+T
Sbjct: 1494 QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAST 1553

Query: 531  YVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTT 590
               +++GS+ T +  + +T  G    S       +   T P         V+ +T   + 
Sbjct: 1554 PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSR 1613

Query: 591  IQGLPGK--NVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIV----TQPKGIGST 644
                P    +  +T L    E T      GA    L  TR  T ++V    T P   GST
Sbjct: 1614 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 1673

Query: 645  VQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNS 704
               A     T     ++  T     P+      +  S  +  +  E+    SR      +
Sbjct: 1674 ETTALPGSTTTAGLSEK-STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTT 1732

Query: 705  SIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQD 764
            +       P    +S++S +    +     P     +S   + +    +  ++ T +  D
Sbjct: 1733 AFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPD 1792

Query: 765  -------------VSSESQSATSTI----KALLELQQTTVKEKLESKPRQPTIDLSQMAV 807
                         V S + S  +T+        + + TT +    SK   P    +  A 
Sbjct: 1793 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAF 1852

Query: 808  PIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEV-AFPLLVSHRSQPQQP---- 862
             ++++     SP S       +   A   T  R++E T V + P+  +    P +     
Sbjct: 1853 -VELSTTSHGSPSS----TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 1907

Query: 863  ---------SQPQRTLLQHVAQSQTATQTSVVVKSIPASS-------PGAITHIMQQALS 906
                     S P  T   H  +S TA+  S   ++  +S+       P   + ++++  S
Sbjct: 1908 LVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTS 1967

Query: 907  SHTA----FTKHSEELGTEEGEVEE---MDTLDPQTGLFYRSALTQSQ----SAKQQKLS 955
             H++     T H  +  T  G  EE     +    TG     A + +      +    +S
Sbjct: 1968 YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPIS 2027

Query: 956  QPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPL----QQEQ 1011
               +E T L   T     +++  T         H  P+ P  ++     T      +   
Sbjct: 2028 SGSMETTALPGSTTTPGLSEKSTTF--------HSSPRSPATTLSPASTTSSGVSEESTT 2079

Query: 1012 AQPKPDVQHT-----QHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQ--APNQ 1064
            +  +P   HT             R   T  + P  T   +L   TT   P  +   + + 
Sbjct: 2080 SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2139

Query: 1065 PKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSS 1124
            P       +P S  +L    E  T      P  T  +     T         T++   + 
Sbjct: 2140 PGSTDTALSPGSTTALSFGQESTTFH--SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2197

Query: 1125 VPKLT-SPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALA----TSM 1179
             P+ T SP +S SP    E TA            Q      H    PP  A A    ++ 
Sbjct: 2198 SPRTTLSPASSTSPGLQGESTAF-----------QTHPASTHTTPSPPSTATAPVEESTT 2246

Query: 1180 LTGEAGSLPSTHMVVAG----------MANSTPQQQKCRESCSSPSTVG-SSLTTRKIDP 1228
                 GS P+TH   +           + +S+P       S +  +T G    TT +I P
Sbjct: 2247 YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 2306

Query: 1229 PAVPAT 1234
             +   T
Sbjct: 2307 GSTEIT 2312



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 182/856 (21%), Positives = 285/856 (33%), Gaps = 148/856 (17%)

Query: 128  ASLPVPAETGSKEVVCY--SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGS 185
            AS P  + TGS        S TST     ST   S   ++  +P   SP S   V    S
Sbjct: 4191 ASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTP---SPPSTTAVPVEVS 4247

Query: 186  TVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIM 245
            T Y           +P     T+ S+SS  + +      V  S   T             
Sbjct: 4248 TTY---------HSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT------------- 4285

Query: 246  QSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK 305
                 +L P  S   +   +P+T   ++ + +    T  P ST    +  KS  + +  +
Sbjct: 4286 ---GTALFPTRSATSVLVGEPTTSPISSGSTET---TALPGSTTTAGLSEKSTTFYSSPR 4339

Query: 306  LVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSP----IPNTVAVTAVVSSTPS 361
               T++  ++T    V    S+ S  S+S  GS  +T  P    +P     +    S+P 
Sbjct: 4340 SPDTTLSPASTTSSGV----SEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPG 4395

Query: 362  VVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421
               +T++ G +T     AS+  P   +  S+P             S +  L         
Sbjct: 4396 STDTTLSPGSTT-----ASSLGPESTTFHSSP------------GSTETTLLPDNTTASG 4438

Query: 422  QVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSK-ILPKPVTAT---- 476
             +   +PV        + L P    T Q     G     Q    SK   P P T T    
Sbjct: 4439 LLEASTPVHSSTGSPHTTLSPAGSTTRQ-----GESTTFQSWPNSKDTTPAPPTTTSAFV 4493

Query: 477  --LPTSSNSPIMVVSSNGAIMTTKL----VTTPTGTQATYTRPTVSPSIGRMAATPGAAT 530
                TS  SP    +++ +  +T L     +T   +    T  T SP+    +     +T
Sbjct: 4494 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 4553

Query: 531  YVKTTSGSIITV-VPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGT 589
               ++ GS  T+  P+S  T G    S+   S TT  I++ P T+   V        + T
Sbjct: 4554 TYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALV-------EEPT 4606

Query: 590  TIQGLPGKNVVT------TLLNAGGEKTIQTVPTGAKPAILTATRPITKMIV----TQPK 639
            +    PG    T      T      E T       A   I+   R  T +++    T P 
Sbjct: 4607 SYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI 4666

Query: 640  GIGS---TVQPAAKIIP---------------TKIVYGQQGKTQVLIKPKPVTFQATVVS 681
              GS   T  P +   P               T   +     T +    +  T  ++ V+
Sbjct: 4667 SSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 4726

Query: 682  EQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIA 741
              T      +   +  V E+       G  +  ++ +SS++S  S +S        H I+
Sbjct: 4727 TATTPSPARS-TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTIS 4785

Query: 742  SRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTID 801
            S     S    A+   PT  +   SS    AT+          TT     ES     + D
Sbjct: 4786 SPPSTTS----ALVEEPTSYH---SSPGSIATTHFPE----SSTTSGRSEESTASHSSPD 4834

Query: 802  LSQMA-VPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQ 860
             + +  +P   T   R + ES +  +    +     +T  T  G      +L S    P 
Sbjct: 4835 TNGITPLPAHFTTSGRIA-ESTTFYISPGSMETTLAST-ATTPGLSAKSTILYSSSRSPD 4892

Query: 861  QPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGT 920
            Q   P             A+ TS       +S  G  T +  QA S+HT     S    T
Sbjct: 4893 QTLSP-------------ASMTS-------SSISGEPTSLYSQAESTHTTAFPAST---T 4929

Query: 921  EEGEVEEMDTLDPQTG 936
              G  +E  T   + G
Sbjct: 4930 TSGLSQESTTFHSKPG 4945



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 78/364 (21%), Positives = 137/364 (37%), Gaps = 43/364 (11%)

Query: 59   STERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANA 118
            ST   R+E  R  +    ++  H +S P S++   +E        P  +  T F   ++ 
Sbjct: 4764 STASGRSEESRTSH----SSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFP-ESST 4818

Query: 119  VANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTST-PVPSGSIATVKSPRPASPASN 177
             +  + +  AS   P   G   +  +  TS     ++T  +  GS+ T  +    +P   
Sbjct: 4819 TSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPG-- 4876

Query: 178  VVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSG 237
               L + ST+   S    D+   P     ++S S  P  L    ++    +   +   SG
Sbjct: 4877 ---LSAKSTILYSSSRSPDQTLSPASMT-SSSISGEPTSLYSQAESTHTTAFPASTTTSG 4932

Query: 238  SPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQK-VIIVTTSPSSTFVPNILSK 296
              + S    S   S    +SP  IT +  + + T   +Q    + T SP+ST VP +  +
Sbjct: 4933 LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992

Query: 297  SHNYAAVTKLVPTSVIA----------STTQKP----------PVVITAS---QSSLVSN 333
            S  + +      T+  +           +T  P          P  +T +   Q S   +
Sbjct: 4993 STTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFH 5052

Query: 334  SSSGSSSSTPSPIPNTVA------VTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPK 387
            SSS ++ +TP P  +T +       T  +S +P+      A   STS +   ST   +  
Sbjct: 5053 SSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASS-STSGLTEESTTFHTSP 5111

Query: 388  SLVS 391
            S  S
Sbjct: 5112 SFTS 5115


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 187/826 (22%), Positives = 291/826 (35%), Gaps = 152/826 (18%)

Query: 136  TGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVV-LPSGSTVYVKS--- 191
            +G  E    S++STT T +S P  + ++    +   +SP S      P  ST   +S   
Sbjct: 338  SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 397

Query: 192  -VSCSDEDEKPR---KRRRTNS-----SSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMS 242
              S S +D         R T S     S++SP+    +    +P S T      G  + S
Sbjct: 398  TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTT----TPGLSERS 453

Query: 243  NIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTS-PSSTFVPNILSKSHNYA 301
                S   S    +SP   T +  S ++T + ++     TT+ P ST  P +   S    
Sbjct: 454  TTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSH 513

Query: 302  AVTKLVPTSVI-ASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTV---------- 350
            +      T+++ ASTT   P     SQ S  S+SSSGS+ +  SP   T           
Sbjct: 514  SSPGSTDTTLLPASTTTSGP-----SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 568

Query: 351  -----------------------AVTAVVSST--------PSVVMSTVAQGVSTS-AIKM 378
                                   A T V SST        P+   S   QG ST+     
Sbjct: 569  HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 628

Query: 379  ASTR-LPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQ 437
            AST   PSP S  +AP +    + +    +P          T    ++ S + H      
Sbjct: 629  ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF--PASSTTSGHSEKSTIFHSSPDAS 686

Query: 438  SPLPPGIKPTIQIKQESGVKIITQQVQP--SKILPKPVTATLPTSSNSPIMVVSS----- 490
               P     T   + ES     T ++ P  ++I   P + T P  S +     SS     
Sbjct: 687  GTTPSSAHSTTSGRGES----TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 742

Query: 491  ---NGAIMTTKLV---TTPTGTQATYTRPTVSPSIGRMAATPG-----AATYVKTTSGSI 539
               + A MT+  V   +T + +Q   T  TVSP+      TPG        Y  +   + 
Sbjct: 743  TTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA---STTTPGLSEESTTVYSSSRGSTE 799

Query: 540  ITVVPKSLAT-LGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKN 598
             TV P S  T + G+  ++      +T  T     S  + +  + T   G+      G  
Sbjct: 800  TTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 859

Query: 599  VVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQ-------PKGIGSTVQPAAKI 651
               T  + G E T     +G+    L+  R  T  +V +       P    +T  P +  
Sbjct: 860  ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 919

Query: 652  IPTKIVYGQQGKTQVLIKPKPVTFQATVVS-EQTRQLVTETLQQASRVAEAGNSSIQEGK 710
             P+             +  K  TF  +  S + T    T T    S   E+  S  Q G 
Sbjct: 920  TPS-------------LSEKSTTFYTSPRSPDATLSPATTTSSGVSE--ESSTSHSQPGS 964

Query: 711  EEPQNYTDSSSSSTES-----SQSSQDSQPVVHVIASR------RQDWSEHEIAMETSPT 759
                 + DS+++S  S     S SSQ S        S       +Q  + H    +T  T
Sbjct: 965  THTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 1024

Query: 760  IIYQD--------VSSESQSAT----------STIKALLELQQTTVKEKLESKPRQPTID 801
            ++  D         S+ + S+T          S+  A L+ + TT +    S    P+  
Sbjct: 1025 LLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS-P 1083

Query: 802  LSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEV 847
                A P++++      P S       +   A   T  R++E T V
Sbjct: 1084 PGTTAAPVEVSTTYHSRPSS----TPTTHFSASSTTLGRSEESTTV 1125



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 266/1346 (19%), Positives = 440/1346 (32%), Gaps = 180/1346 (13%)

Query: 77   TTIAHNMSGPNSS--SEWSIEGRRLVPLMPRLVPQTAFTVTA----NAVANAAIQHNASL 130
            +T +H+  GP  +  S  S     L P       +   T T     N  A+  ++  AS+
Sbjct: 179  STASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE--ASM 236

Query: 131  PVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLP-------S 183
            PV + T S         STT    ST   S    + K  RPA P +    +        S
Sbjct: 237  PVHSSTRSPHTTLSPAGSTTRQGESTTFHSW--PSSKDTRPAPPTTTSAFVEPSTTSHGS 294

Query: 184  GSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSN 243
             S++    +S         +   T  SS         P++     +      S S     
Sbjct: 295  PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 354

Query: 244  IMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAV 303
            I  + + +      P     +  ST TT+         TTS  S    +  S S   A  
Sbjct: 355  ISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS----TTSGRSE--ESTASHSSQDATG 408

Query: 304  TKLVP----TSVIASTTQKPPVVITASQSSLVSNSSS----GSSSSTPSPIPNTVAVTAV 355
            T ++P    TSV+   +   P+   + +++ +  S++       S+T    P + A T  
Sbjct: 409  TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 468

Query: 356  VSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQV 415
             +ST S   S V++  +TS  +  ST   +     + P                      
Sbjct: 469  PASTTS---SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 525

Query: 416  QQQTQQQVAQPSPVSHQQQ-PQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVT 474
               T    +Q S  SH       + L PG    +   QES           + + P   T
Sbjct: 526  ASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTT 585

Query: 475  ATLPTSSNSPIMVVSSNGAIMTTKLVTTPTG-----------TQATYTRPTVSPSIGRMA 523
            ++    +++   V SS G+  TT    + T            T    T  T SP     A
Sbjct: 586  SSGIVEAST--RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATA 643

Query: 524  ATPGAATYVKTTSGSIITVVPKSLATLG----GKIISSNIVSGTTTKITTIPMTSKPNVI 579
                + TY ++   +  T  P S  T G      I  S+  +  TT  +    TS     
Sbjct: 644  PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 703

Query: 580  VVQKTTGKGTTIQGLPGKNVVTTLLNAGGE--KTIQTVPTGAKPAILTATRPITKMIV-- 635
               + +   T I  LPG      L  A      + ++  T   PA +T+     +     
Sbjct: 704  TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 763

Query: 636  TQPKGIGSTVQPAAKIIP------TKIVYGQQGKTQVLIKP----------KPVTFQATV 679
            +QP    STV PA+   P      T +    +G T+  + P          +P TF +  
Sbjct: 764  SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRP 823

Query: 680  VSEQ----TRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQP 735
             S      T    T  L + S       +S Q G        D    ST    SS  +  
Sbjct: 824  ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 883

Query: 736  VVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKP 795
             +    S     +   +  E++P+ +     S S + T+T+                  P
Sbjct: 884  KLSPARS-----TTSGLVGESTPSRL-----SPSSTETTTL------------------P 915

Query: 796  RQPTI-DLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT--EVAFPLL 852
              PT   LS+ +     +     +  SP  A   S  V+E  +T  +  G+    AFP  
Sbjct: 916  GSPTTPSLSEKSTTFYTSPRSPDATLSP--ATTTSSGVSEESSTSHSQPGSTHTTAFPDS 973

Query: 853  VSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFT 912
             +     Q+P+            SQ +T+ ++   S  ASS G      QQ+ + H++  
Sbjct: 974  TTTSDLSQEPTTSH--------SSQGSTEATLSPGSTTASSLG------QQSTTFHSS-- 1017

Query: 913  KHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQT---QLQVKTL 969
                  G  E  +   DT+   +GL   S  T S +        P    +   Q +  T 
Sbjct: 1018 -----PGDTETTLLPDDTI--TSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF 1070

Query: 970  QCFQTKQKQT--------IHLQADQLQHKLPQMPQLSIRHQKLTPL--QQEQAQPKPDVQ 1019
            Q + +    T          ++     H  P     +      T L   +E         
Sbjct: 1071 QSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPG 1130

Query: 1020 HTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPK---IYVQPQTPQS 1076
             T   +         L+ +P  + +   + +TT        A    K    Y  P++P +
Sbjct: 1131 ATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 1190

Query: 1077 QMSLPASSEKQTASQVEQPIITQGSSVTKITFEG--RQPPTVTKITGGSSVPKLTSPVTS 1134
             +S PAS+     S+      ++  S     F G    P    + T   S P  T   T+
Sbjct: 1191 TLS-PASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD--TT 1247

Query: 1135 ISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSML---TGEAGSLPSTH 1191
            +SP   +  +   +           +T +       P    A+ +L   T    S  S H
Sbjct: 1248 LSPGSTTASSLGPESTTFHSSPGSTETTL------LPDNTTASGLLEASTPVHSSTGSPH 1301

Query: 1192 MVVAGMANSTPQQQ--------KCRESCSSPSTVGSS---LTTRKIDPPAVPATGQFMRI 1240
              ++   ++T Q +          +++  +P T  S+   L+T     P+   T  F   
Sbjct: 1302 TTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 1361

Query: 1241 QNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPS-------GLLELNNFTSQQLDD 1293
                 +  E +       A      P  S+++ +VE S       G  +  +F       
Sbjct: 1362 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 1421

Query: 1294 EETAMEQDIDSSTEDGTEPSPSQSSA 1319
              +   +   SST       PS +SA
Sbjct: 1422 GRSEESRTSHSSTTHTISSPPSTTSA 1447



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 206/906 (22%), Positives = 321/906 (35%), Gaps = 161/906 (17%)

Query: 136 TGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCS 195
           +G  E     + STT T +STP  + ++A   S   +  ++        ST+  +S    
Sbjct: 10  SGHSEESATFHGSTTHTKSSTPSTTAALAHT-SYHSSLGSTETTHFRDSSTISGRSEESK 68

Query: 196 DEDEKPRKRRRT---NSSSSSPVVLKEVPKAVVPVS-KTITVPVS----GSPKMSNIMQS 247
                P     T     S+ S +V    P  +   S +T  +P S    G  + S    S
Sbjct: 69  ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYS 128

Query: 248 IANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTS-PSSTFVPNI-----LSKSHNYA 301
              S      P  +T +  S ++T + ++     TT+ P ST +P +      S S    
Sbjct: 129 SPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 188

Query: 302 AVTKLVPTSVIAST----------------TQKPPVVITAS---QSSLVSNSSSGSSSST 342
             T L P S  AS+                T   P   TAS   ++S+  +SS+ S  +T
Sbjct: 189 TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTT 248

Query: 343 PSPIPNTV--AVTAVVSSTPSVVMSTVAQGVSTSA-IKMASTRLPSPKSL------VSAP 393
            SP  +T     +    S PS   +  A   +TSA ++ ++T   SP S+        + 
Sbjct: 249 LSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARST 308

Query: 394 TQILAQFPKQHQQSP--KQQLYQVQQQTQQQVAQPSPVSHQ-----------------QQ 434
           T  L +    +  SP   Q ++  +  T     + S  SH                  ++
Sbjct: 309 TSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE 368

Query: 435 PQQSPLPPGIKPTIQI---------KQESGVKIITQQVQPSKILPKPVTAT--LPTSSNS 483
           P      PG   T             +ES     +Q    + +LP   T +  L  S+ S
Sbjct: 369 PTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 428

Query: 484 PIMVVSSNGAIMTTKL---VTTPTGTQATYT--------RPTVSPSIGRMAATPGAATYV 532
           PI    S+G++ TT L    TTP  ++ + T          T+SP+    +     +T  
Sbjct: 429 PI----SSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 484

Query: 533 KTTSGSI-ITVVPKSLATLG----GKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGK 587
           ++  GS   T  P S  T G         S+  S  TT +     TS P+       +  
Sbjct: 485 RSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSS 544

Query: 588 GTTIQGL-PGKNVVTTLLNAGGEK-TIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTV 645
           G+T   L PG    TT L+ G E  T  + P      +   +   + ++    +   ST 
Sbjct: 545 GSTDTALSPGS---TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 601

Query: 646 QPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSS 705
            P   + P          T   ++ +   FQ    S  T      T    + V E+    
Sbjct: 602 SPRTTLSPA-------SSTSPGLQGESTAFQTHPASTHTTPSPPST--ATAPVEESTTYH 652

Query: 706 IQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDV 765
              G     ++  SS++S  S +S+     + H              A  T+P+  +   
Sbjct: 653 RSPGSTPTTHFPASSTTSGHSEKST-----IFH----------SSPDASGTTPSSAHSTT 697

Query: 766 SSESQSATSTIK----ALLELQQTTVKEKLE-------SKPRQPTIDLSQMAVPIQMTQE 814
           S   +S TS I      +  L  +T    L        S PR PT  LS    P  MT  
Sbjct: 698 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS----PASMT-- 751

Query: 815 KRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVA 874
                         S  V E  TT R+  G+  +    VS  S        + T +   +
Sbjct: 752 --------------SLGVGEESTTSRSQPGSTHS---TVSPASTTTPGLSEESTTV--YS 792

Query: 875 QSQTATQTSVVVKSIPASSPG-AITHIMQQALSSHTA-FTKHSEELG-TEEGEVEEMDTL 931
            S+ +T+T+V   S   S  G   T    +  S+HT  FT+ S   G TEE         
Sbjct: 793 SSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 852

Query: 932 DPQTGL 937
             QTGL
Sbjct: 853 STQTGL 858



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 81/322 (25%), Positives = 121/322 (37%), Gaps = 44/322 (13%)

Query: 85   GPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCY 144
            GP S++  S  G     L+P            N  A+  ++  AS PV + TGS      
Sbjct: 1259 GPESTTFHSSPGSTETTLLPD-----------NTTASGLLE--ASTPVHSSTGSPHTTLS 1305

Query: 145  SYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKR 204
               STT    ST   S   +    P P +  S  V L + S               P   
Sbjct: 1306 PAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS------------HGSPSST 1353

Query: 205  RRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKI-TF 263
              T+ S+SS  + +      V  S  +    + SP  S     +  S   H SP    T 
Sbjct: 1354 PTTHFSASSTTLGRSEESTTVH-SSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM 1412

Query: 264  TKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIAS-----TTQK 318
              P + T +  +++     TS SST   + +S   +  +     PTS  +S     TT  
Sbjct: 1413 HFPESSTASGRSEE---SRTSHSST--THTISSPPSTTSALVEEPTSYHSSPGSIATTHF 1467

Query: 319  PPVVITA--SQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSST----PSVVMSTVAQGVS 372
            P    T+  S+ S  S+SS  ++  TP P   T +     S+T    P  + +T+A   +
Sbjct: 1468 PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTAT 1527

Query: 373  TSAIKMASTRLPSPKSLVSAPT 394
            T  +   ST L +   LV  PT
Sbjct: 1528 TPGLSAKSTILYT-SDLVGEPT 1548



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 214/1117 (19%), Positives = 358/1117 (32%), Gaps = 149/1117 (13%)

Query: 320  PVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVS---------------------- 357
            P   T S  S  S +  GS++ T S  P+T A  A  S                      
Sbjct: 4    PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63

Query: 358  --------STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPK 409
                    S+P  + +TV    ST ++ +     PSP S  S  T  L     +   S K
Sbjct: 64   SEESKASHSSPDAMATTVLPAGSTPSV-LVGDSTPSPISSGSMETTALPGSTTKPGLSEK 122

Query: 410  QQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLP---PGIKPTIQIKQESGVKIITQQVQPS 466
               +    ++      P+ ++     ++S      PG   T      + +  ++Q+   S
Sbjct: 123  STTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTAS 182

Query: 467  KILPKPVTATLPTSSNSPIMV-------VSSNGAIMTTKL-----------VTTPTGTQA 508
               P P   TL   S +   +        S  G+  TT L            + P  +  
Sbjct: 183  HSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSST 242

Query: 509  TYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKIT 568
                 T+SP+ G       + T+    S       P +  +   +  +++  S ++   T
Sbjct: 243  RSPHTTLSPA-GSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT 301

Query: 569  TIPMTSKPNVIVVQKTT---GKGTT-------IQGLPGKNVVTTLLNAGGEKTIQTVPTG 618
             I   S  + +V + TT     G+T            G+   +T  ++    TI + P+ 
Sbjct: 302  HISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST 361

Query: 619  AKPAI-----------LTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVL 667
                +            TAT        T  +   ST   +++     IV   +  T VL
Sbjct: 362  TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL 421

Query: 668  IKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESS 727
            +       ++T     +  + T  L  ++        S           T  S +ST SS
Sbjct: 422  LG------ESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSS 475

Query: 728  QSSQDSQPVVHVIASRRQDWSEHEIAMETSPTI--IYQDVSSESQSATSTIKALLELQQT 785
              S++S        SR +  S H  A   S T   + +  ++   S  ST   LL    T
Sbjct: 476  GVSEES------TTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 529

Query: 786  TVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGT 845
            T     ES     +   +  A+    T       ES +                 T  G 
Sbjct: 530  TSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGI 589

Query: 846  EVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQAL 905
              A   + S    P+    P  +    +    TA QT         S P   T  ++++ 
Sbjct: 590  VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 649

Query: 906  SSH----TAFTKHSEELGTEEGEVEE---MDTLDPQTGLFYRSALTQSQSAKQQKLSQPP 958
            + H    +  T H     T  G  E+     +    +G    SA + +    +   S+  
Sbjct: 650  TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR-- 707

Query: 959  LEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPL-QQEQAQPKPD 1017
            +     ++ TL    T    +   +A    +  P+ P  ++    +T L   E++     
Sbjct: 708  ISPGSTEITTLPGSTTTPGLS---EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 764

Query: 1018 VQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQ 1077
               + H  V+     P     P  +        +++   +    P+     V  + P + 
Sbjct: 765  QPGSTHSTVS-----PASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTF 819

Query: 1078 MSLPAS------SEKQTASQVEQ--------PIITQ-GSSVTKITFEGRQPPTVTKITGG 1122
             S PAS      +E  T S + +        P  TQ G   T  T +  +  T    + G
Sbjct: 820  HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 879

Query: 1123 SSVPKLT------------SPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDP 1170
            S+  KL+            S  + +SP      T        SL E            D 
Sbjct: 880  STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 939

Query: 1171 P-KKALATSMLTGEAGSLP-----STHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTR 1224
                A  TS    E  S       STH       +ST      +E  +S S+ GS+  T 
Sbjct: 940  TLSPATTTSSGVSEESSTSHSQPGSTH--TTAFPDSTTTSDLSQEPTTSHSSQGSTEATL 997

Query: 1225 KIDPPAVPATGQFMRI--QNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLE 1282
                    + GQ       + G  +    P + I   + + + P HSS+  +      L 
Sbjct: 998  SPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL---HTTLT 1054

Query: 1283 LNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSA 1319
              + TS  L +E T  +    SS    T PSP  ++A
Sbjct: 1055 PASSTSAGLQEESTTFQSWPSSS---DTTPSPPGTTA 1088


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 198/1025 (19%), Positives = 367/1025 (35%), Gaps = 120/1025 (11%)

Query: 114  VTANAVANAAIQHNASLPVPAETGSKEVV------CYSYTSTTSTPT----STPVPSGSI 163
            +T      + +   +   +  E G K+ V      C   T TT+T T    STP   GS+
Sbjct: 1585 ITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSV 1644

Query: 164  ATVKSPRPASPASNVVVLPSGSTV---YVKSVSCSDEDE--------KPRKRRRTNSSSS 212
              +     +       V  S +T     V S++ S E          K  + ++T S ++
Sbjct: 1645 DIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTA 1704

Query: 213  SPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMS----PVKITFTKPST 268
             P   K V K     S   ++ V  +  +  + +       P+ +    P    +  PS 
Sbjct: 1705 LPSYRKFVTK-----SSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSP 1759

Query: 269  QTTNTTTQKVIIVTTSPSS--TFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITAS 326
            + T   T +  + T    +  + +  +L  S  +  +    P     + T+     IT +
Sbjct: 1760 RPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTT 1819

Query: 327  QSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSP 386
            +  ++     G            +     V  TP    +   +G+ +SA++      P  
Sbjct: 1820 E--IIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQ 1877

Query: 387  KSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKP 446
               V   T +  +         + +L++++   ++   + +    QQ  ++         
Sbjct: 1878 TGPVIIETWVAEE---------ELELWEIRAFAERVEKEKAQAVEQQAKKR--------- 1919

Query: 447  TIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMT-TKLV-TTPT 504
               ++Q+    I T    P+       + T   S    +MV   +G++ T TK+V TT  
Sbjct: 1920 ---LEQQKPTVIATSTTSPTS------STTSTISPAQKVMVAPISGSVTTGTKMVLTTKV 1970

Query: 505  GTQATYTRPTVSPSIGRMAATPGAATYVKT--TSGSIITVVPKSLATLGGKIISSNIVSG 562
            G+ AT T                 AT+VK   ++  ++ V  K L  +     +S   + 
Sbjct: 1971 GSPATVTFQQ------NKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQ-QTF 2023

Query: 563  TTTKITTIPMTSKPNVIVVQKTTGKGTTIQG---LPGKNVVTTLLNAG--GEKTIQT--- 614
            T+ +  T  +T +PN      TT     I G    PG  V+ T L     G+  I+T   
Sbjct: 2024 TSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVM 2083

Query: 615  VPTGAKPAILTAT---RPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPK 671
            V  GA   ++T     +P++   V+ P  + ST    +    T     Q   +Q    P+
Sbjct: 2084 VQPGAPQQVMTQIIRGQPVSTA-VSAPNTVSSTPGQKSLTSATSTSNIQSSASQ---PPR 2139

Query: 672  PVTFQATVVSEQTRQLVTET--LQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQS 729
            P   Q  +   Q  QL       Q  + V +    +  + +  PQ  T       +  Q+
Sbjct: 2140 PQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQA 2199

Query: 730  SQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKE 789
            +  +  V   + +     +       T+ T +    +   +   S +   +++ Q     
Sbjct: 2200 AMPNGTVQRFLFT---PLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLP 2256

Query: 790  KLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAF 849
              +S    P     Q A P    Q +   P+SP+   V+++   +  TT  +   +E   
Sbjct: 2257 PAQSSSVGPAEAQPQTAQPSAQPQPQTQ-PQSPAQPEVQTQPEVQTQTTVSSHVPSEAQP 2315

Query: 850  PLLVSHRSQPQQPSQPQRTLL-QHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSH 908
                S + Q    SQPQ  +  Q   + Q+ +QT +   +    SPG  + + Q   S  
Sbjct: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQV-QTTTSQP 2374

Query: 909  TAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKT 968
                 H+      +G+ +    +   T       L+  Q+  Q  +S P   Q Q+Q   
Sbjct: 2375 IPIQPHTSLQIPSQGQPQSQPQVQSST-----QTLSSGQTLNQVTVSSPSRPQLQIQ--- 2426

Query: 969  LQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAK 1028
                   Q Q   +   QLQ ++  + Q+  +      + Q QAQ     Q  +  +  +
Sbjct: 2427 -------QPQPQVIAVPQLQQQVQVLSQIQSQ-----VVAQIQAQQSGVPQQIKLQLPIQ 2474

Query: 1029 DRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQT 1088
             +Q   +     Q VV V A    +QL ++QQ  +Q     Q +  Q Q+ +      Q 
Sbjct: 2475 IQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQ-----QQKKKQQQIEIKREHTLQA 2529

Query: 1089 ASQVE 1093
            ++Q E
Sbjct: 2530 SNQSE 2534



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 111/589 (18%), Positives = 204/589 (34%), Gaps = 87/589 (14%)

Query: 24   ELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNM 83
            E+ A+A  +   +AQ    + KK L  +   V++ ST    +     ++  +   +A   
Sbjct: 1896 EIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPIS 1955

Query: 84   SGPNSSSEWSIEGRRLVPL-----MPRLVPQTAFTVTANAVANAAI---QHNASLPVPAE 135
                + ++  +  +   P        +   QT  T      +N+ +   Q      +P+ 
Sbjct: 1956 GSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSS 2015

Query: 136  TGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPAS-----PASNVVVLPSGSTVYVK 190
            TG+ +    S+   T+T T  P  SGS  T  + +  +     P   V+  P   +   K
Sbjct: 2016 TGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGK 2075

Query: 191  SVSCSDEDEKPRKRRR--TNSSSSSPV-VLKEVPKAV--VPVSKTITVPVSGSPKMSNIM 245
            ++  +    +P   ++  T      PV      P  V   P  K++T   S     SNI 
Sbjct: 2076 AIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATS----TSNIQ 2131

Query: 246  QSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTK 305
             S +    P    VK+T  + +  T      + + V           ++          +
Sbjct: 2132 SSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTV-----------VIQGQGQTTGQLQ 2180

Query: 306  LVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMS 365
            L+P  V         ++  A  +  V              +   +A TA  +ST +  +S
Sbjct: 2181 LIPQGVTVLPGPGQQLMQAAMPNGTVQRF-----------LFTPLATTATTASTTTTTVS 2229

Query: 366  TVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQ 425
            T A G         S ++   +     P Q  +  P            + Q QT Q  AQ
Sbjct: 2230 TTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPA-----------EAQPQTAQPSAQ 2278

Query: 426  PSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLP--TSSNS 483
            P P +  Q P Q        P +Q + E   +       PS+  P    ++ P   + + 
Sbjct: 2279 PQPQTQPQSPAQ--------PEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQ 2330

Query: 484  PIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVV 543
            P     SN    +   V +P+ T+   + P+          +PG  + V+TT+   I + 
Sbjct: 2331 P----QSNVQGQSPVRVQSPSQTRIRPSTPS--------QLSPGQQSQVQTTTSQPIPIQ 2378

Query: 544  PKSLATLGG----------KIISSNIVSGTTTKITTIPMTSKPNVIVVQ 582
            P +   +            +  +  + SG T    T+   S+P + + Q
Sbjct: 2379 PHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ 2427



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 178/1024 (17%), Positives = 340/1024 (33%), Gaps = 111/1024 (10%)

Query: 171  PASPASNVVVLPSGSTVYVKS-VSCSDEDEKPRKRRRTNSSSSSPVV------LKEVPKA 223
            P +   ++ V  S    ++   V   D +E+     +++  SSS         L+ +P  
Sbjct: 1448 PENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPST 1507

Query: 224  VVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTT 283
                S   T P +  P+ +++ Q     +    S VK   + P T    +      I   
Sbjct: 1508 KESDSTQTTTPSASCPESNSVNQ--VEDMEIETSEVKKVTSSPITSEEESNLSNDFIDEN 1565

Query: 284  SPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTP 343
                    N+  +S     +T++   +   +T  K  + +       V +S+   + ST 
Sbjct: 1566 GLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTV 1625

Query: 344  SPIPNTVAVTAVVSSTPSV-VMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPK 402
            +    TV   +  S+  SV ++S   Q  +     +  +   +  +LV++ T       K
Sbjct: 1626 TTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMT-----VSK 1680

Query: 403  QHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQ---ESGVKII 459
            ++    K +L +  +  + +     P   +   + S     + P   +K+   + G++  
Sbjct: 1681 EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIR-- 1738

Query: 460  TQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSI 519
              +V       KP     P  S  P   ++    + T K +   +              +
Sbjct: 1739 --EVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDM 1796

Query: 520  GRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSN---------IVSGTTTKITTI 570
               A   G  T  +T+   I T        +G   I S          I    T K T  
Sbjct: 1797 AAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPT 1856

Query: 571  PMTS-------KPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKT----IQTVPTGA 619
            P          +P      K TG       +  + +    + A  E+      Q V   A
Sbjct: 1857 PQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQA 1916

Query: 620  KPAILTATRPITKMIVTQP-KGIGSTVQPAAKIIPTKIVYGQQGKTQVLI-----KPKPV 673
            K  +      +     T P     ST+ PA K++   I       T++++      P  V
Sbjct: 1917 KKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATV 1976

Query: 674  TFQ---------ATVVSE-QTRQLVTETLQQASRVAEAGNSSIQEG--KEEPQNYTDSSS 721
            TFQ         AT V + Q+   V +  Q+   +  +   + Q+     +P+  T +  
Sbjct: 1977 TFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIR 2036

Query: 722  SSTESSQSSQDSQPVVHVIASR------RQDWSEHEIAMETSPTIIYQDVSSESQSATST 775
             +T  S  +  +  V+     R      R    +  +      T +     +  Q  T  
Sbjct: 2037 PNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQI 2096

Query: 776  IKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVA-- 833
            I+        +    + S P Q ++  +     IQ +  +   P+   + +  ++L    
Sbjct: 2097 IRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLT 2156

Query: 834  ------EYITTERTDEGTEVA--------FPLLVSHRSQPQQPSQPQRTLLQHVAQSQTA 879
                  + +T     +G              +L     Q  Q + P  T+ + +      
Sbjct: 2157 QGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLAT 2216

Query: 880  TQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGL-- 937
            T T+    +   S+  A T   +Q+  S        + L   +          PQT    
Sbjct: 2217 TATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPS 2276

Query: 938  FYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQL 997
                  TQ QS  Q ++   P  QTQ    T+      + Q  H Q+ + Q      PQ 
Sbjct: 2277 AQPQPQTQPQSPAQPEVQTQPEVQTQT---TVSSHVPSEAQPTHAQSSKPQVAAQSQPQS 2333

Query: 998  SIRHQKLTPLQQ-EQAQPKPDVQHTQHPMVAKDRQLPTLMAQP----PQTVVQVLAVKTT 1052
            +++ Q    +Q   Q + +P       P   +  Q+ T  +QP    P T +Q+ +    
Sbjct: 2334 NVQGQSPVRVQSPSQTRIRPSTPSQLSP--GQQSQVQTTTSQPIPIQPHTSLQIPSQGQP 2391

Query: 1053 QQLPKLQQA-----------------PNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQP 1095
            Q  P++Q +                 P++P++ +Q   PQ         + Q  SQ++  
Sbjct: 2392 QSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQ 2451

Query: 1096 IITQ 1099
            ++ Q
Sbjct: 2452 VVAQ 2455



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 69/326 (21%), Positives = 117/326 (35%), Gaps = 59/326 (18%)

Query: 150  TSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNS 209
            T+ P++ P P          +P SPA      P   T        +     P + + T++
Sbjct: 2272 TAQPSAQPQPQ--------TQPQSPAQ-----PEVQTQPEVQTQTTVSSHVPSEAQPTHA 2318

Query: 210  SSSSP-VVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP-HMSPVKITFTKPS 267
             SS P V  +  P++ V     + V    SP  + I  S  + L P   S V+ T ++P 
Sbjct: 2319 QSSKPQVAAQSQPQSNVQGQSPVRVQ---SPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2375

Query: 268  TQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQ 327
                +T+ Q    + +       P + S +   ++   L    V  S+  +P + I   Q
Sbjct: 2376 PIQPHTSLQ----IPSQGQPQSQPQVQSSTQTLSSGQTL--NQVTVSSPSRPQLQIQQPQ 2429

Query: 328  SSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPK 387
              +++             +P       V+S   S V++ +    S               
Sbjct: 2430 PQVIA-------------VPQLQQQVQVLSQIQSQVVAQIQAQQS--------------- 2461

Query: 388  SLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPT 447
                 P QI  Q P Q QQS   Q +Q+Q     Q A       + Q  +       +  
Sbjct: 2462 ---GVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQ 2518

Query: 448  IQIKQESGVKIITQQVQPSKILPKPV 473
            I+IK+E  ++   Q    S+I+ K V
Sbjct: 2519 IEIKREHTLQASNQ----SEIIQKQV 2540


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.120    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,430,305
Number of Sequences: 37866
Number of extensions: 2474227
Number of successful extensions: 22848
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 147
Number of HSP's successfully gapped in prelim test: 753
Number of HSP's that attempted gapping in prelim test: 11806
Number of HSP's gapped (non-prelim): 5311
length of query: 1322
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1208
effective length of database: 13,930,794
effective search space: 16828399152
effective search space used: 16828399152
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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