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Search of human proteins with 19923437
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923437 adenylate kinase 3 [Homo sapiens]
(227 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923437 adenylate kinase 3 [Homo sapiens] 455 e-128
gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens] 279 1e-75
gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens] 279 1e-75
gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens] 279 1e-75
gi|4502013 adenylate kinase 2 isoform a [Homo sapiens] 174 6e-44
gi|7524346 adenylate kinase 2 isoform b [Homo sapiens] 174 6e-44
gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo... 89 3e-18
gi|4502011 adenylate kinase 1 [Homo sapiens] 85 6e-17
gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens] 75 4e-14
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 70 2e-12
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 70 2e-12
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 56 2e-08
gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo... 55 4e-08
gi|145699133 KPL2 protein isoform 1 [Homo sapiens] 37 0.011
gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens] 34 0.12
gi|7706212 TAF9 RNA polymerase II, TATA box binding protein-asso... 32 0.58
gi|148727333 adenylate kinase 7 [Homo sapiens] 32 0.58
gi|24307899 Era-like 1 [Homo sapiens] 32 0.58
gi|62865612 TAF9 RNA polymerase II, TATA box binding protein-ass... 31 0.99
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 31 0.99
gi|14589900 mitogen-activated protein kinase kinase 6 [Homo sapi... 29 2.9
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 29 3.8
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 29 3.8
gi|59823631 G protein-coupled receptor 125 [Homo sapiens] 29 3.8
gi|125628636 keratin 80 isoform a [Homo sapiens] 28 4.9
gi|125628632 keratin 80 isoform b [Homo sapiens] 28 4.9
gi|116006953 polycystin 1-like 2 isoform c [Homo sapiens] 28 6.4
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 28 6.4
gi|112421013 signal-induced proliferation-associated 1 like 2 [H... 28 6.4
>gi|19923437 adenylate kinase 3 [Homo sapiens]
Length = 227
Score = 455 bits (1171), Expect = e-128
Identities = 227/227 (100%), Positives = 227/227 (100%)
Query: 1 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI 60
MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI
Sbjct: 1 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI 60
Query: 61 DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV 120
DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV
Sbjct: 61 DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV 120
Query: 121 IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT 180
IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
Sbjct: 121 IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT 180
Query: 181 KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP 227
KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
Sbjct: 181 KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP 227
>gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens]
Length = 223
Score = 279 bits (714), Expect = 1e-75
Identities = 132/221 (59%), Positives = 170/221 (76%), Gaps = 1/221 (0%)
Query: 4 SARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQG 63
+++LLRAVI+G PGSGKGTV RI +F L+HLSSG LR+N+ TE+G +AK +I++
Sbjct: 2 ASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKS 61
Query: 64 KLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQ 123
L+PD V+TRL + EL+N WLLDGFPRTL QAEALD+ ++D VI+LN+PFE +K
Sbjct: 62 LLVPDHVITRLMMSELENRRGQHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFETLKD 121
Query: 124 RLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPV 183
RL+ RWIHP SGRVYN++FNPP GIDD+TGEPL+Q+EDDKPE V RL+ Y+D KPV
Sbjct: 122 RLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPV 181
Query: 184 LEYYQKKGVLETFSGTETNKIWPYVYAFLQTKV-PQRSQKA 223
+E Y+ +GVL FSGTETNKIWPYVY K+ P +S++A
Sbjct: 182 IELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEA 222
>gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens]
Length = 223
Score = 279 bits (714), Expect = 1e-75
Identities = 132/221 (59%), Positives = 170/221 (76%), Gaps = 1/221 (0%)
Query: 4 SARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQG 63
+++LLRAVI+G PGSGKGTV RI +F L+HLSSG LR+N+ TE+G +AK +I++
Sbjct: 2 ASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKS 61
Query: 64 KLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQ 123
L+PD V+TRL + EL+N WLLDGFPRTL QAEALD+ ++D VI+LN+PFE +K
Sbjct: 62 LLVPDHVITRLMMSELENRRGQHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFETLKD 121
Query: 124 RLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPV 183
RL+ RWIHP SGRVYN++FNPP GIDD+TGEPL+Q+EDDKPE V RL+ Y+D KPV
Sbjct: 122 RLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPV 181
Query: 184 LEYYQKKGVLETFSGTETNKIWPYVYAFLQTKV-PQRSQKA 223
+E Y+ +GVL FSGTETNKIWPYVY K+ P +S++A
Sbjct: 182 IELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEA 222
>gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens]
Length = 223
Score = 279 bits (714), Expect = 1e-75
Identities = 132/221 (59%), Positives = 170/221 (76%), Gaps = 1/221 (0%)
Query: 4 SARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQG 63
+++LLRAVI+G PGSGKGTV RI +F L+HLSSG LR+N+ TE+G +AK +I++
Sbjct: 2 ASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKS 61
Query: 64 KLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQ 123
L+PD V+TRL + EL+N WLLDGFPRTL QAEALD+ ++D VI+LN+PFE +K
Sbjct: 62 LLVPDHVITRLMMSELENRRGQHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFETLKD 121
Query: 124 RLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPV 183
RL+ RWIHP SGRVYN++FNPP GIDD+TGEPL+Q+EDDKPE V RL+ Y+D KPV
Sbjct: 122 RLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPV 181
Query: 184 LEYYQKKGVLETFSGTETNKIWPYVYAFLQTKV-PQRSQKA 223
+E Y+ +GVL FSGTETNKIWPYVY K+ P +S++A
Sbjct: 182 IELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEA 222
>gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
Length = 239
Score = 174 bits (441), Expect = 6e-44
Identities = 89/200 (44%), Positives = 134/200 (67%), Gaps = 6/200 (3%)
Query: 8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIP 67
+RAV++G PG+GKGT + R+ +F + HL++GD+LR + G+E+G KA +D GKL+
Sbjct: 16 IRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVS 75
Query: 68 DDVMTRLALHELKN-LTQYSWLLDGFPRTLPQAEALD-----RAYQIDTVINLNVPFEVI 121
D+++ L L+ L + +LLDGFPRT+ QAE LD R ++D+VI ++P ++
Sbjct: 76 DEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLL 135
Query: 122 KQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTK 181
+R+T R IHP SGR Y+ EFNPPK DD+TGEPLI+R DD + + RL+AY QT
Sbjct: 136 IRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTT 195
Query: 182 PVLEYYQKKGVLETFSGTET 201
P++EYY+K+G+ ++T
Sbjct: 196 PLIEYYRKRGIHSAIDASQT 215
>gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
Length = 232
Score = 174 bits (441), Expect = 6e-44
Identities = 89/200 (44%), Positives = 134/200 (67%), Gaps = 6/200 (3%)
Query: 8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIP 67
+RAV++G PG+GKGT + R+ +F + HL++GD+LR + G+E+G KA +D GKL+
Sbjct: 16 IRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVS 75
Query: 68 DDVMTRLALHELKN-LTQYSWLLDGFPRTLPQAEALD-----RAYQIDTVINLNVPFEVI 121
D+++ L L+ L + +LLDGFPRT+ QAE LD R ++D+VI ++P ++
Sbjct: 76 DEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLL 135
Query: 122 KQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTK 181
+R+T R IHP SGR Y+ EFNPPK DD+TGEPLI+R DD + + RL+AY QT
Sbjct: 136 IRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTT 195
Query: 182 PVLEYYQKKGVLETFSGTET 201
P++EYY+K+G+ ++T
Sbjct: 196 PLIEYYRKRGIHSAIDASQT 215
>gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo
sapiens]
Length = 479
Score = 89.0 bits (219), Expect = 3e-18
Identities = 59/215 (27%), Positives = 108/215 (50%), Gaps = 11/215 (5%)
Query: 9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPD 68
R +++G GSGK ++ + + L ++ G LL++ + T G L + F ++ +PD
Sbjct: 270 RVLLLGPVGSGKSLQAALLAQKYRLVNVCCGQLLKEAVADRTTFGELIQPFFEKEMAVPD 329
Query: 69 DVMTRLALHEL--KNLTQYSWLLDGFPRTLPQAEALDR-AYQIDTVINLNVPFEVIKQRL 125
++ ++ L ++ Q W+L G PR L QA L+R Y + V LNVPF+ I +RL
Sbjct: 330 SLLMKVLSQRLDQQDCIQKGWVLHGVPRDLDQAHLLNRLGYNPNRVFFLNVPFDSIMERL 389
Query: 126 TARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLE 185
T R I P +G Y++ + PP T+ I L+Q D E V ++ + + + +
Sbjct: 390 TLRRIDPVTGERYHLMYKPPPTMEIQ----ARLLQNPKDAEEQVKLKMDLFYRNSADLEQ 445
Query: 186 YYQKKGVLETFSG-TETNKIWPYVYAFLQTKVPQR 219
Y G T +G + ++ Y+ + + +P++
Sbjct: 446 LY---GSAITLNGDQDPYTVFEYIESGIINPLPKK 477
Score = 56.2 bits (134), Expect = 2e-08
Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 15/184 (8%)
Query: 9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRG--TEIGVLAKAFIDQGKLI 66
R VI+G P SGK T++ + KHL+S L +N++ + A+ Q K +
Sbjct: 59 RIVILGPPASGKTTIAMWL-----CKHLNSSLLTLENLILNEFSYTATEARRLYLQRKTV 113
Query: 67 PDDVMTRLALHEL--KNLTQYSWLLDGFPRTLPQAEALDR-AYQIDTVINLNVPFEVIKQ 123
P ++ +L L ++ + W+LDG P T QA + VI L+ P V+ +
Sbjct: 114 PSALLVQLIQERLAEEDCIKQGWILDGIPETREQALRIQTLGITPRHVIVLSAPDTVLIE 173
Query: 124 RLTARWIHPASGRVYNIEFN-PPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKP 182
R + I P +G +Y+ F+ PP++ ++ ++ + + ET K L+ + + +
Sbjct: 174 RNLGKRIDPQTGEIYHTTFDWPPES----EIQNRLMVPEDISELETAQKLLEYHRNIVRV 229
Query: 183 VLEY 186
+ Y
Sbjct: 230 IPSY 233
>gi|4502011 adenylate kinase 1 [Homo sapiens]
Length = 194
Score = 84.7 bits (208), Expect = 6e-17
Identities = 56/185 (30%), Positives = 91/185 (49%), Gaps = 30/185 (16%)
Query: 12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVM 71
++G PGSGKGT +I + HLS+GDLLR + G+ G +++G+L+P + +
Sbjct: 13 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETV 72
Query: 72 TRLALHEL--KNLTQYSWLLDGFPRTLPQAEALDRAY-QIDTVINLNVPFEVIKQRLTAR 128
+ + K T +L+DG+PR + Q E +R Q ++ ++ E + QRL R
Sbjct: 73 LDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKR 132
Query: 129 WIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQ 188
SGRV DD ET+ KRL+ Y T+PV+ +Y+
Sbjct: 133 --GETSGRV-------------------------DDNEETIKKRLETYYKATEPVIAFYE 165
Query: 189 KKGVL 193
K+G++
Sbjct: 166 KRGIV 170
>gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]
Length = 228
Score = 75.5 bits (184), Expect = 4e-14
Identities = 54/211 (25%), Positives = 99/211 (46%), Gaps = 40/211 (18%)
Query: 4 SARLLRAVI---MGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLR-GTEIGVLAKAF 59
S RL++ ++ +G PG+GKGT +RI + HLS+G+LLRD ++ G L + +
Sbjct: 29 SPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKY 88
Query: 60 IDQGKLIPDDVMTRLALHEL-----KNLTQYSWLLDGFPRTLPQAE----ALDRAYQIDT 110
I +GK++P ++ L E+ N + +L+DGFPR + +D +
Sbjct: 89 IKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSF 148
Query: 111 VINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVI 170
V+ + E+ +R R +SG R DD E++
Sbjct: 149 VLFFDCNNEICIERCLER--GKSSG-------------------------RSDDNRESLE 181
Query: 171 KRLKAYEDQTKPVLEYYQKKGVLETFSGTET 201
KR++ Y TKP+++ Y++ G ++ +++
Sbjct: 182 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKS 212
>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
Length = 562
Score = 69.7 bits (169), Expect = 2e-12
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 30/193 (15%)
Query: 12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVM 71
I+G PGSGKGT ++ + HLS+G+LLR+ + +E L + +++G L+P ++
Sbjct: 381 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 440
Query: 72 TRLALHELKNL--TQYSWLLDGFPRTLPQAEALDRAY-QIDTVINLNVPFEVIKQRLTAR 128
L + +L+DG+PR + Q E R VI ++ + + RL R
Sbjct: 441 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQR 500
Query: 129 WIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQ 188
++ +DD T +T+ KRL+AY + PV+ YY+
Sbjct: 501 ---------------SRSSLPVDDTT------------KTIAKRLEAYYRASIPVIAYYE 533
Query: 189 KKGVLETFSGTET 201
K L + T
Sbjct: 534 TKTQLHKINAEGT 546
Score = 62.0 bits (149), Expect = 4e-10
Identities = 50/191 (26%), Positives = 91/191 (47%), Gaps = 33/191 (17%)
Query: 11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNM---LRGTEIGVLAKAFIDQGKLIP 67
+++G PGSGKGT S +I + +++S G+LLR + + ++AK I G+L P
Sbjct: 136 LVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK-IITTGELAP 194
Query: 68 DDV-MTRLALHELKNLTQYSWLLDGFPRTLPQAEAL-DRAYQIDTVINLNVPFEVIKQRL 125
+ +T + ++ + ++DGFPR + QA + D+ D V+ L + +K+RL
Sbjct: 195 QETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERL 254
Query: 126 TARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLE 185
R + G P DD + +RL ++ P+++
Sbjct: 255 LKR----------------------AEQQGRP-----DDNVKATQRRLMNFKQNAAPLVK 287
Query: 186 YYQKKGVLETF 196
Y+Q+KG++ TF
Sbjct: 288 YFQEKGLIMTF 298
>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
Length = 536
Score = 69.7 bits (169), Expect = 2e-12
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 30/193 (15%)
Query: 12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVM 71
I+G PGSGKGT ++ + HLS+G+LLR+ + +E L + +++G L+P ++
Sbjct: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414
Query: 72 TRLALHELKNL--TQYSWLLDGFPRTLPQAEALDRAY-QIDTVINLNVPFEVIKQRLTAR 128
L + +L+DG+PR + Q E R VI ++ + + RL R
Sbjct: 415 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQR 474
Query: 129 WIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQ 188
++ +DD T +T+ KRL+AY + PV+ YY+
Sbjct: 475 ---------------SRSSLPVDDTT------------KTIAKRLEAYYRASIPVIAYYE 507
Query: 189 KKGVLETFSGTET 201
K L + T
Sbjct: 508 TKTQLHKINAEGT 520
Score = 62.0 bits (149), Expect = 4e-10
Identities = 50/191 (26%), Positives = 91/191 (47%), Gaps = 33/191 (17%)
Query: 11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNM---LRGTEIGVLAKAFIDQGKLIP 67
+++G PGSGKGT S +I + +++S G+LLR + + ++AK I G+L P
Sbjct: 110 LVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK-IITTGELAP 168
Query: 68 DDV-MTRLALHELKNLTQYSWLLDGFPRTLPQAEAL-DRAYQIDTVINLNVPFEVIKQRL 125
+ +T + ++ + ++DGFPR + QA + D+ D V+ L + +K+RL
Sbjct: 169 QETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERL 228
Query: 126 TARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLE 185
R + G P DD + +RL ++ P+++
Sbjct: 229 LKR----------------------AEQQGRP-----DDNVKATQRRLMNFKQNAAPLVK 261
Query: 186 YYQKKGVLETF 196
Y+Q+KG++ TF
Sbjct: 262 YFQEKGLIMTF 272
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 56.2 bits (134), Expect = 2e-08
Identities = 42/123 (34%), Positives = 69/123 (56%), Gaps = 5/123 (4%)
Query: 8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRD--NMLRGTEIGVLAKAFIDQGKL 65
+R +I+G P SGK TV+ +IT+ + LKHLS G LR N TE+ ++ + +G
Sbjct: 1412 IRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGMT 1471
Query: 66 IPDDV-MTRLALHELKNLTQYSW-LLDGFPRTLPQAEALDRAYQIDTVI-NLNVPFEVIK 122
PD++ + L L ++++ + ++DG+P T Q L+ I VI L+VP + I
Sbjct: 1472 APDELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELSVPSKEIF 1531
Query: 123 QRL 125
+RL
Sbjct: 1532 KRL 1534
Score = 55.5 bits (132), Expect = 4e-08
Identities = 36/148 (24%), Positives = 76/148 (51%), Gaps = 10/148 (6%)
Query: 11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDV 70
V+ G PG GK T++ IT ++ + + +L + + TE GV+ ++ + G+ IPD++
Sbjct: 34 VVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQSIPDEL 93
Query: 71 MTRLALHELKN--LTQYSWLLDGFP-------RTLPQAEALDRA-YQIDTVINLNVPFEV 120
+ +L L +L + + + +++ P TL Q E + + D +IN+ P
Sbjct: 94 VIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPDYD 153
Query: 121 IKQRLTARWIHPASGRVYNIEFNPPKTV 148
+ QR++ + H +G +Y+ + P+ +
Sbjct: 154 LCQRISGQRQHNNTGYIYSRDQWDPEVI 181
>gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo
sapiens]
Length = 421
Score = 55.5 bits (132), Expect = 4e-08
Identities = 36/148 (24%), Positives = 76/148 (51%), Gaps = 10/148 (6%)
Query: 11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDV 70
V+ G PG GK T++ IT ++ + + +L + + TE GV+ ++ + G+ IPD++
Sbjct: 34 VVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQSIPDEL 93
Query: 71 MTRLALHELKN--LTQYSWLLDGFP-------RTLPQAEALDRA-YQIDTVINLNVPFEV 120
+ +L L +L + + + +++ P TL Q E + + D +IN+ P
Sbjct: 94 VIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPDYD 153
Query: 121 IKQRLTARWIHPASGRVYNIEFNPPKTV 148
+ QR++ + H +G +Y+ + P+ +
Sbjct: 154 LCQRISGQRQHNNTGYIYSRDQWDPEVI 181
>gi|145699133 KPL2 protein isoform 1 [Homo sapiens]
Length = 1822
Score = 37.4 bits (85), Expect = 0.011
Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 5/142 (3%)
Query: 51 EIGVLAKAFIDQGKLIPDDVMTRLALHELKNL-TQYSWLLDGFPRTLPQAEALDRAYQID 109
++G ++ + +GK IPD ++ + ++ + + +LDGFP TL QA+ L+ A
Sbjct: 685 QLGAKSEQLLKKGKSIPDVLLVDIIVNAINEIPVNQDCILDGFPMTLNQAQLLEEAL--- 741
Query: 110 TVINLNV-PFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPET 168
T N N+ E K + + I PA+ + + V + D++ + R +D
Sbjct: 742 TGCNRNLTEVERKKAQKSTLAIDPATSKEIPLPSPAFDFVILLDVSDTSSMSRMNDIIAE 801
Query: 169 VIKRLKAYEDQTKPVLEYYQKK 190
+ A+ED ++ V Q K
Sbjct: 802 ELSYKTAHEDISQRVAAENQDK 823
>gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens]
Length = 179
Score = 33.9 bits (76), Expect = 0.12
Identities = 12/41 (29%), Positives = 26/41 (63%)
Query: 161 REDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTET 201
R DD E++ KR++ Y TKP+++ Y++ G ++ +++
Sbjct: 123 RSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKS 163
>gi|7706212 TAF9 RNA polymerase II, TATA box binding
protein-associated factor isoform b [Homo sapiens]
Length = 172
Score = 31.6 bits (70), Expect = 0.58
Identities = 13/37 (35%), Positives = 22/37 (59%)
Query: 11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNML 47
++ G PG GK T+ + + LK+++ GDL R+ L
Sbjct: 7 LLTGTPGVGKTTLGKELASKSGLKYINVGDLAREEQL 43
>gi|148727333 adenylate kinase 7 [Homo sapiens]
Length = 723
Score = 31.6 bits (70), Expect = 0.58
Identities = 23/126 (18%), Positives = 52/126 (41%), Gaps = 31/126 (24%)
Query: 8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLR------------GTE---- 51
++ I+G P GK +++ + +++L H+ D++ + + + G E
Sbjct: 368 IKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEE 427
Query: 52 -------------IGVLAKAFIDQGKLIPDDVMTRLALHELKNL--TQYSWLLDGFPRTL 96
+ + ++ + D + R +LK++ ++LDGFP+T
Sbjct: 428 EEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKTY 487
Query: 97 PQAEAL 102
QA+ L
Sbjct: 488 DQAKDL 493
>gi|24307899 Era-like 1 [Homo sapiens]
Length = 437
Score = 31.6 bits (70), Expect = 0.58
Identities = 12/27 (44%), Positives = 22/27 (81%)
Query: 1 MGASARLLRAVIMGAPGSGKGTVSSRI 27
M ++R+LR V++GAP +GK T+S+++
Sbjct: 107 MPENSRVLRVVLLGAPNAGKSTLSNQL 133
>gi|62865612 TAF9 RNA polymerase II, TATA box binding
protein-associated factor isoform c [Homo sapiens]
Length = 169
Score = 30.8 bits (68), Expect = 0.99
Identities = 13/34 (38%), Positives = 20/34 (58%)
Query: 14 GAPGSGKGTVSSRITTHFELKHLSSGDLLRDNML 47
G PG GK T+ + + LK+++ GDL R+ L
Sbjct: 7 GTPGVGKTTLGKELASKSGLKYINVGDLAREEQL 40
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 30.8 bits (68), Expect = 0.99
Identities = 30/123 (24%), Positives = 51/123 (41%), Gaps = 11/123 (8%)
Query: 13 MGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMT 72
MG PG G+ +S R+ + F + +++ + + GT I + F ++ K I +V+T
Sbjct: 2531 MGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPI-GNVVT 2589
Query: 73 RLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTV----INLNVPFEVIKQRLTAR 128
L Y+ ++ F T + L I V + N F K +T
Sbjct: 2590 E------ATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRL 2643
Query: 129 WIH 131
WIH
Sbjct: 2644 WIH 2646
>gi|14589900 mitogen-activated protein kinase kinase 6 [Homo
sapiens]
Length = 334
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/61 (29%), Positives = 29/61 (47%)
Query: 22 TVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKN 81
TV T F GD+ L T + K ID+G+ IP+D++ ++A+ +K
Sbjct: 106 TVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKA 165
Query: 82 L 82
L
Sbjct: 166 L 166
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 28.9 bits (63), Expect = 3.8
Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 144 PPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYY 187
P ++ + D E L+ R DKP TV RL E++TKP+ ++
Sbjct: 2281 PVVSISVHD--DEELLPRALDKPVTVQFRLLETEERTKPICVFW 2322
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 28.9 bits (63), Expect = 3.8
Identities = 13/41 (31%), Positives = 20/41 (48%)
Query: 13 MGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIG 53
MG PG G+ TV+ R+ HF + D + + T +G
Sbjct: 2343 MGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILG 2383
>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
Length = 1321
Score = 28.9 bits (63), Expect = 3.8
Identities = 24/89 (26%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 105 AYQIDTVINLNVPFEVIKQRLTARWIHPASGRVY----NIEFNPPKTVGIDDLTGEPLIQ 160
AY + T + +V + K RL H S R Y ++NPP+ D + P
Sbjct: 1191 AYDVPTSVEGSVQNGLPKSRLGNNEGHSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSS 1250
Query: 161 REDDKPETVIKRLKAYEDQTKPVLEYYQK 189
R +KP + + A LE QK
Sbjct: 1251 RNFEKPVSTTSKKDALRKPAVVELENQQK 1279
>gi|125628636 keratin 80 isoform a [Homo sapiens]
Length = 452
Score = 28.5 bits (62), Expect = 4.9
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 53 GVLAKAFIDQGKLIPDDVMTRLALHELKN--LTQYSWLLDGFPRTLPQAEALDRAYQI 108
G ++K ++ G L+P DV A+ +LKN + L D F + + +AL++ Q+
Sbjct: 53 GTISKVTVNPGLLVPLDVKLDPAVQQLKNQEKEEMKALNDKFASLIGKVQALEQRNQL 110
>gi|125628632 keratin 80 isoform b [Homo sapiens]
Length = 422
Score = 28.5 bits (62), Expect = 4.9
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 53 GVLAKAFIDQGKLIPDDVMTRLALHELKN--LTQYSWLLDGFPRTLPQAEALDRAYQI 108
G ++K ++ G L+P DV A+ +LKN + L D F + + +AL++ Q+
Sbjct: 53 GTISKVTVNPGLLVPLDVKLDPAVQQLKNQEKEEMKALNDKFASLIGKVQALEQRNQL 110
>gi|116006953 polycystin 1-like 2 isoform c [Homo sapiens]
Length = 991
Score = 28.1 bits (61), Expect = 6.4
Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 21/99 (21%)
Query: 69 DVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQI--------------DTVINL 114
D++ R+ + E + +SW LD P QAE L A ++ + + L
Sbjct: 679 DILLRVTMGEDSPVAMFSWYLDNTP--TEQAEPLLDACRLRGFWPRSLTLLQSNTSTLLL 736
Query: 115 NVPF-----EVIKQRLTARWIHPASGRVYNIEFNPPKTV 148
N F EVI+ R TA H Y I PP+ V
Sbjct: 737 NSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREV 775
>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
Length = 2459
Score = 28.1 bits (61), Expect = 6.4
Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 21/99 (21%)
Query: 69 DVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQI--------------DTVINL 114
D++ R+ + E + +SW LD P QAE L A ++ + + L
Sbjct: 679 DILLRVTMGEDSPVAMFSWYLDNTP--TEQAEPLLDACRLRGFWPRSLTLLQSNTSTLLL 736
Query: 115 NVPF-----EVIKQRLTARWIHPASGRVYNIEFNPPKTV 148
N F EVI+ R TA H Y I PP+ V
Sbjct: 737 NSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREV 775
>gi|112421013 signal-induced proliferation-associated 1 like 2 [Homo
sapiens]
Length = 1722
Score = 28.1 bits (61), Expect = 6.4
Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 18 SGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEI-GVLAKAFIDQGKLIPDDVM 71
S T+SS +++ + KH SGDL+ +L T I G + ID +P ++
Sbjct: 1224 SSSNTLSSNTSSNSDDKHFGSGDLMDPELLGLTYIKGASTDSGIDTAPCMPATIL 1278
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,468,303
Number of Sequences: 37866
Number of extensions: 363390
Number of successful extensions: 916
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 863
Number of HSP's gapped (non-prelim): 40
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.