Guide to the Human Genome
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Search of human proteins with 19923350

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923350 nuclear factor of activated T-cells, cytosolic
component 1 isoform B [Homo sapiens]
         (825 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923350 nuclear factor of activated T-cells, cytosolic compo...  1708   0.0  
gi|27502386 nuclear factor of activated T-cells, cytosolic compo...  1625   0.0  
gi|27502391 nuclear factor of activated T-cells, cytosolic compo...  1625   0.0  
gi|27502393 nuclear factor of activated T-cells, cytosolic compo...  1435   0.0  
gi|27502388 nuclear factor of activated T-cells, cytosolic compo...   726   0.0  
gi|27886539 nuclear factor of activated T-cells, cytoplasmic, ca...   580   e-165
gi|27886541 nuclear factor of activated T-cells, cytoplasmic, ca...   580   e-165
gi|209862843 nuclear factor of activated T-cells, cytoplasmic, c...   580   e-165
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca...   561   e-160
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca...   561   e-160
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca...   561   e-160
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal...   561   e-160
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...   427   e-119
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...   427   e-119
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom...   218   1e-56
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo...   218   1e-56
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho...   218   1e-56
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho...   218   1e-56
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom...   218   1e-56
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ...    61   4e-09
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ...    60   6e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    56   1e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   3e-06
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               51   5e-06
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              47   6e-05
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                47   9e-05
gi|157168329 formin 1 [Homo sapiens]                                   46   1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   2e-04
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            45   3e-04
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    45   3e-04

>gi|19923350 nuclear factor of activated T-cells, cytosolic
           component 1 isoform B [Homo sapiens]
          Length = 825

 Score = 1708 bits (4423), Expect = 0.0
 Identities = 825/825 (100%), Positives = 825/825 (100%)

Query: 1   MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT 60
           MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
Sbjct: 1   MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT 60

Query: 61  AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI 120
           AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
Sbjct: 61  AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI 120

Query: 121 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR 180
           EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
Sbjct: 121 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR 180

Query: 181 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240
           SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
Sbjct: 181 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240

Query: 241 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW 300
           SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
Sbjct: 241 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW 300

Query: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
           LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
Sbjct: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360

Query: 361 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP 420
           PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
Sbjct: 361 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP 420

Query: 421 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT 480
           SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
Sbjct: 421 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT 480

Query: 481 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR 540
           ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
Sbjct: 481 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR 540

Query: 541 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK 600
           NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
Sbjct: 541 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK 600

Query: 601 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI 660
           QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
Sbjct: 601 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI 660

Query: 661 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQ 720
           PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQ
Sbjct: 661 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQ 720

Query: 721 GLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGV 780
           GLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGV
Sbjct: 721 GLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGV 780

Query: 781 ASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 825
           ASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ
Sbjct: 781 ASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 825


>gi|27502386 nuclear factor of activated T-cells, cytosolic
           component 1 isoform C [Homo sapiens]
          Length = 930

 Score = 1625 bits (4207), Expect = 0.0
 Identities = 784/787 (99%), Positives = 785/787 (99%)

Query: 39  SAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 98
           +A  EHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA
Sbjct: 26  AAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 85

Query: 99  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 158
           GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS
Sbjct: 86  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 145

Query: 159 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 218
           LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE
Sbjct: 146 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 205

Query: 219 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 278
           EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS
Sbjct: 206 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 265

Query: 279 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 338
           PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT
Sbjct: 266 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 325

Query: 339 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 398
           TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK
Sbjct: 326 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 385

Query: 399 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 458
           PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH
Sbjct: 386 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 445

Query: 459 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 518
           PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE
Sbjct: 446 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 505

Query: 519 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 578
           IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL
Sbjct: 506 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 565

Query: 579 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 638
           QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH
Sbjct: 566 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 625

Query: 639 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV 698
           VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV
Sbjct: 626 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV 685

Query: 699 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 758
           PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM
Sbjct: 686 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 745

Query: 759 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP 818
           PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP
Sbjct: 746 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP 805

Query: 819 PALLPQQ 825
           PALLPQQ
Sbjct: 806 PALLPQQ 812


>gi|27502391 nuclear factor of activated T-cells, cytosolic
           component 1 isoform E [Homo sapiens]
          Length = 812

 Score = 1625 bits (4207), Expect = 0.0
 Identities = 784/787 (99%), Positives = 785/787 (99%)

Query: 39  SAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 98
           +A  EHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA
Sbjct: 26  AAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 85

Query: 99  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 158
           GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS
Sbjct: 86  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 145

Query: 159 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 218
           LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE
Sbjct: 146 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 205

Query: 219 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 278
           EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS
Sbjct: 206 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 265

Query: 279 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 338
           PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT
Sbjct: 266 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 325

Query: 339 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 398
           TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK
Sbjct: 326 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 385

Query: 399 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 458
           PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH
Sbjct: 386 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 445

Query: 459 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 518
           PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE
Sbjct: 446 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 505

Query: 519 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 578
           IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL
Sbjct: 506 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 565

Query: 579 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 638
           QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH
Sbjct: 566 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 625

Query: 639 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV 698
           VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV
Sbjct: 626 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV 685

Query: 699 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 758
           PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM
Sbjct: 686 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 745

Query: 759 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP 818
           PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP
Sbjct: 746 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP 805

Query: 819 PALLPQQ 825
           PALLPQQ
Sbjct: 806 PALLPQQ 812


>gi|27502393 nuclear factor of activated T-cells, cytosolic
           component 1 isoform A [Homo sapiens]
          Length = 716

 Score = 1435 bits (3715), Expect = 0.0
 Identities = 697/697 (100%), Positives = 697/697 (100%)

Query: 1   MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT 60
           MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
Sbjct: 1   MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT 60

Query: 61  AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI 120
           AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
Sbjct: 61  AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI 120

Query: 121 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR 180
           EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
Sbjct: 121 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR 180

Query: 181 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240
           SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
Sbjct: 181 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240

Query: 241 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW 300
           SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
Sbjct: 241 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW 300

Query: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
           LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
Sbjct: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360

Query: 361 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP 420
           PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
Sbjct: 361 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP 420

Query: 421 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT 480
           SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
Sbjct: 421 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT 480

Query: 481 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR 540
           ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
Sbjct: 481 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR 540

Query: 541 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK 600
           NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
Sbjct: 541 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK 600

Query: 601 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI 660
           QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
Sbjct: 601 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI 660

Query: 661 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697
           PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN
Sbjct: 661 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697


>gi|27502388 nuclear factor of activated T-cells, cytosolic
           component 1 isoform D [Homo sapiens]
          Length = 353

 Score =  726 bits (1874), Expect = 0.0
 Identities = 353/353 (100%), Positives = 353/353 (100%)

Query: 473 MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID 532
           MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID
Sbjct: 1   MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID 60

Query: 533 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA 592
           CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA
Sbjct: 61  CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA 120

Query: 593 QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK 652
           QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK
Sbjct: 121 QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK 180

Query: 653 PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA 712
           PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA
Sbjct: 181 PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA 240

Query: 713 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS 772
           PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS
Sbjct: 241 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS 300

Query: 773 PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 825
           PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ
Sbjct: 301 PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 353


>gi|27886539 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform B [Homo sapiens]
          Length = 921

 Score =  580 bits (1495), Expect = e-165
 Identities = 378/837 (45%), Positives = 472/837 (56%), Gaps = 94/837 (11%)

Query: 29  PAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPC----------HNLQTSTPG 78
           P    GG+ +   +    +    ++P    P AH     P           + L+  +P 
Sbjct: 16  PGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPL 75

Query: 79  IIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHD 138
                + P  +G     GP   FLS+   +P GA  L SPRIEIT      H   Q    
Sbjct: 76  ASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQAVGP 127

Query: 139 VEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYES 191
           + + D     ++ P          TL +P  E YR+P CLSPASS SS S          
Sbjct: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS---------- 177

Query: 192 NYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESW 251
                + S   SP+ SPCVSP    P++  P+         SPR SP  SPR S+ E+S 
Sbjct: 178 -----FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAEDSC 231

Query: 252 LGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD-SW 300
           LG  S      SR +SP  KR++S    L    P  SP  S +PSP  S  V+  D  S 
Sbjct: 232 LGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSP 291

Query: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
            G      S+ I+ A+N+L TDS      G+P K  KT+ +  P            + + 
Sbjct: 292 AGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------VSAA 335

Query: 361 PPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----TSYM 408
           P  A      Y + + +       R+    +  L VP     W  PKPL P     +  +
Sbjct: 336 PSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICSIPV 390

Query: 409 SPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLE 468
           + +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA  GGHP+VQLHGY+E
Sbjct: 391 TASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYME 450

Query: 469 NEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMR 528
           N+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MR
Sbjct: 451 NKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMR 510

Query: 529 AVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECS 588
           A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECS
Sbjct: 511 ATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECS 570

Query: 589 QRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDR 648
           QRSA ELP+VE+Q TDS  V GG++M+L+G NF  +SKV+F EK  DG  +WEMEA  D+
Sbjct: 571 QRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDK 630

Query: 649 DLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDD 708
           D  +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P  VP IKTEPTD+
Sbjct: 631 DKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEPTDE 688

Query: 709 YEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKL 768
           Y+P   C P   GL    +PYY Q   +   P SCLVA   PC Q  T + ++P    + 
Sbjct: 689 YDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDARYQQ 744

Query: 769 HDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 823
            + +   Y +   S     LG  QPA  A   ++ D  R V  H GS GQ    L P
Sbjct: 745 QNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800


>gi|27886541 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform C [Homo sapiens]
          Length = 925

 Score =  580 bits (1495), Expect = e-165
 Identities = 378/837 (45%), Positives = 472/837 (56%), Gaps = 94/837 (11%)

Query: 29  PAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPC----------HNLQTSTPG 78
           P    GG+ +   +    +    ++P    P AH     P           + L+  +P 
Sbjct: 16  PGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPL 75

Query: 79  IIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHD 138
                + P  +G     GP   FLS+   +P GA  L SPRIEIT      H   Q    
Sbjct: 76  ASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQAVGP 127

Query: 139 VEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYES 191
           + + D     ++ P          TL +P  E YR+P CLSPASS SS S          
Sbjct: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS---------- 177

Query: 192 NYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESW 251
                + S   SP+ SPCVSP    P++  P+         SPR SP  SPR S+ E+S 
Sbjct: 178 -----FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAEDSC 231

Query: 252 LGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD-SW 300
           LG  S      SR +SP  KR++S    L    P  SP  S +PSP  S  V+  D  S 
Sbjct: 232 LGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSP 291

Query: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
            G      S+ I+ A+N+L TDS      G+P K  KT+ +  P            + + 
Sbjct: 292 AGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------VSAA 335

Query: 361 PPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----TSYM 408
           P  A      Y + + +       R+    +  L VP     W  PKPL P     +  +
Sbjct: 336 PSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICSIPV 390

Query: 409 SPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLE 468
           + +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA  GGHP+VQLHGY+E
Sbjct: 391 TASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYME 450

Query: 469 NEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMR 528
           N+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MR
Sbjct: 451 NKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMR 510

Query: 529 AVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECS 588
           A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECS
Sbjct: 511 ATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECS 570

Query: 589 QRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDR 648
           QRSA ELP+VE+Q TDS  V GG++M+L+G NF  +SKV+F EK  DG  +WEMEA  D+
Sbjct: 571 QRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDK 630

Query: 649 DLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDD 708
           D  +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P  VP IKTEPTD+
Sbjct: 631 DKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEPTDE 688

Query: 709 YEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKL 768
           Y+P   C P   GL    +PYY Q   +   P SCLVA   PC Q  T + ++P    + 
Sbjct: 689 YDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDARYQQ 744

Query: 769 HDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 823
            + +   Y +   S     LG  QPA  A   ++ D  R V  H GS GQ    L P
Sbjct: 745 QNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800


>gi|209862843 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform D [Homo sapiens]
          Length = 901

 Score =  580 bits (1495), Expect = e-165
 Identities = 378/824 (45%), Positives = 469/824 (56%), Gaps = 91/824 (11%)

Query: 32  RAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGA 91
           R  G++   E   +  AS    PA P            + L+  +P      + P  +G 
Sbjct: 16  RIMGSVDQEEPNAHKVASPPSGPAYPDDVLD-------YGLKPYSPLASLSGEPPGRFGE 68

Query: 92  ALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRS 151
               GP   FLS+   +P GA  L SPRIEIT      H   Q    + + D     ++ 
Sbjct: 69  PDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQAVGPLRMRDAGLLVEQP 120

Query: 152 PSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSP 204
           P          TL +P  E YR+P CLSPASS SS S               + S   SP
Sbjct: 121 PLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS---------------FISDTFSP 165

Query: 205 WQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARS------SR 258
           + SPCVSP    P++  P+         SPR SP  SPR S+ E+S LG  S      SR
Sbjct: 166 YTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAEDSCLGRHSPVPRPASR 224

Query: 259 PASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD-SWLGNTTQYTSSAIV 313
            +SP  KR++S    L    P  SP  S +PSP  S  V+  D  S  G      S+ I+
Sbjct: 225 SSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIM 284

Query: 314 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 373
            A+N+L TDS      G+P K  KT+ +  P            + + P  A      Y +
Sbjct: 285 DALNSLATDSPC----GIPPKMWKTSPDPSP------------VSAAPSKAGLPRHIYPA 328

Query: 374 FQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----TSYMSPTLPALDWQLPS 421
            + +       R+    +  L VP     W  PKPL P     +  ++ +LP L+W L S
Sbjct: 329 VEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICSIPVTASLPPLEWPLSS 383

Query: 422 HSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTA 481
            SG YELRIEVQPK HHRAHYETEGSRGAVKA  GGHP+VQLHGY+EN+PL LQ+FIGTA
Sbjct: 384 QSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTA 443

Query: 482 DDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRN 541
           D+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MRA IDCAGILKLRN
Sbjct: 444 DERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRN 503

Query: 542 SDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQ 601
           +DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECSQRSA ELP+VE+Q
Sbjct: 504 ADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQ 563

Query: 602 STDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIP 661
            TDS  V GG++M+L+G NF  +SKV+F EK  DG  +WEMEA  D+D  +PN L VEIP
Sbjct: 564 DTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIP 623

Query: 662 PFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQG 721
            +RN+ I +PV V+FYV NGKRKRSQ Q FTY P  VP IKTEPTD+Y+P   C P   G
Sbjct: 624 EYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEPTDEYDPTLICSPTHGG 681

Query: 722 LSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVA 781
           L    +PYY Q   +   P SCLVA   PC Q  T + ++P    +  + +   Y +   
Sbjct: 682 LG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDARYQQQNPAAVLYQRS-K 736

Query: 782 SPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 823
           S     LG  QPA  A   ++ D  R V  H GS GQ    L P
Sbjct: 737 SLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 780


>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 1 [Homo sapiens]
          Length = 1075

 Score =  561 bits (1446), Expect = e-160
 Identities = 355/754 (47%), Positives = 454/754 (60%), Gaps = 71/754 (9%)

Query: 24  GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
           GE   PAP   G+ + A+ E    AS  +    P P+  +T L  P H L + +  + P 
Sbjct: 19  GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77

Query: 83  ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
               S   Y    +   + Y        P G P   E P I+ITS     H   +    D
Sbjct: 78  FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130

Query: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYESNYSYPY 197
           +++ D        PS   L LP   +YR+ S   SPASS+SSRS  S+ASS ES  S+ Y
Sbjct: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCES-LSHIY 189

Query: 198 ----------------ASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPS 239
                            SP TSP  SP  C   +T   + G    L       SPR SP 
Sbjct: 190 DDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPC 242

Query: 240 TSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGS 290
            SPR+SVT+E+WL  R     SSRP SPC KR++S    +  Y    SPHHSP PSP  S
Sbjct: 243 HSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHS 300

Query: 291 PRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKV 350
           PR SVT+D+WL N + +  S +  A+         D    +P+K+RKT+ +Q   +  K+
Sbjct: 301 PRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKL 355

Query: 351 EPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMS 409
           E   +D GS  P  + + +D    Q+  K   C DQ+L+VP  P+ W+KPKP     + +
Sbjct: 356 ELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRT 414

Query: 410 PTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLEN 469
            +LP LDW LP+H G  EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E 
Sbjct: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473

Query: 470 EPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRA 529
           +P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533

Query: 530 VIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQ 589
            IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQ
Sbjct: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593

Query: 590 RSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRD 649
           RSAQELP +EK S +S  V GG +MV++G NFL +SK+IF+EK  DG   WE+E K  R+
Sbjct: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653

Query: 650 LCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDY 709
            C+   +V+E+PP+ N  +T+ V V FY+CNGKRK+SQ QRFTY P    ++K E  ++ 
Sbjct: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV---LMKQEHREEI 710

Query: 710 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSC 743
           + +      S    P+P P  +Q+   P   S C
Sbjct: 711 DLS------SVPSLPVPHPAQTQR---PSSDSGC 735


>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 4 [Homo sapiens]
          Length = 1045

 Score =  561 bits (1446), Expect = e-160
 Identities = 355/754 (47%), Positives = 454/754 (60%), Gaps = 71/754 (9%)

Query: 24  GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
           GE   PAP   G+ + A+ E    AS  +    P P+  +T L  P H L + +  + P 
Sbjct: 19  GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77

Query: 83  ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
               S   Y    +   + Y        P G P   E P I+ITS     H   +    D
Sbjct: 78  FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130

Query: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYESNYSYPY 197
           +++ D        PS   L LP   +YR+ S   SPASS+SSRS  S+ASS ES  S+ Y
Sbjct: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCES-LSHIY 189

Query: 198 ----------------ASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPS 239
                            SP TSP  SP  C   +T   + G    L       SPR SP 
Sbjct: 190 DDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPC 242

Query: 240 TSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGS 290
            SPR+SVT+E+WL  R     SSRP SPC KR++S    +  Y    SPHHSP PSP  S
Sbjct: 243 HSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHS 300

Query: 291 PRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKV 350
           PR SVT+D+WL N + +  S +  A+         D    +P+K+RKT+ +Q   +  K+
Sbjct: 301 PRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKL 355

Query: 351 EPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMS 409
           E   +D GS  P  + + +D    Q+  K   C DQ+L+VP  P+ W+KPKP     + +
Sbjct: 356 ELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRT 414

Query: 410 PTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLEN 469
            +LP LDW LP+H G  EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E 
Sbjct: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473

Query: 470 EPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRA 529
           +P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533

Query: 530 VIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQ 589
            IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQ
Sbjct: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593

Query: 590 RSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRD 649
           RSAQELP +EK S +S  V GG +MV++G NFL +SK+IF+EK  DG   WE+E K  R+
Sbjct: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653

Query: 650 LCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDY 709
            C+   +V+E+PP+ N  +T+ V V FY+CNGKRK+SQ QRFTY P    ++K E  ++ 
Sbjct: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV---LMKQEHREEI 710

Query: 710 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSC 743
           + +      S    P+P P  +Q+   P   S C
Sbjct: 711 DLS------SVPSLPVPHPAQTQR---PSSDSGC 735


>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 3 [Homo sapiens]
          Length = 1065

 Score =  561 bits (1446), Expect = e-160
 Identities = 355/754 (47%), Positives = 454/754 (60%), Gaps = 71/754 (9%)

Query: 24  GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
           GE   PAP   G+ + A+ E    AS  +    P P+  +T L  P H L + +  + P 
Sbjct: 19  GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77

Query: 83  ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
               S   Y    +   + Y        P G P   E P I+ITS     H   +    D
Sbjct: 78  FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130

Query: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYESNYSYPY 197
           +++ D        PS   L LP   +YR+ S   SPASS+SSRS  S+ASS ES  S+ Y
Sbjct: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCES-LSHIY 189

Query: 198 ----------------ASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPS 239
                            SP TSP  SP  C   +T   + G    L       SPR SP 
Sbjct: 190 DDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPC 242

Query: 240 TSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGS 290
            SPR+SVT+E+WL  R     SSRP SPC KR++S    +  Y    SPHHSP PSP  S
Sbjct: 243 HSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHS 300

Query: 291 PRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKV 350
           PR SVT+D+WL N + +  S +  A+         D    +P+K+RKT+ +Q   +  K+
Sbjct: 301 PRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKL 355

Query: 351 EPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMS 409
           E   +D GS  P  + + +D    Q+  K   C DQ+L+VP  P+ W+KPKP     + +
Sbjct: 356 ELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRT 414

Query: 410 PTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLEN 469
            +LP LDW LP+H G  EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E 
Sbjct: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473

Query: 470 EPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRA 529
           +P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533

Query: 530 VIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQ 589
            IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQ
Sbjct: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593

Query: 590 RSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRD 649
           RSAQELP +EK S +S  V GG +MV++G NFL +SK+IF+EK  DG   WE+E K  R+
Sbjct: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653

Query: 650 LCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDY 709
            C+   +V+E+PP+ N  +T+ V V FY+CNGKRK+SQ QRFTY P    ++K E  ++ 
Sbjct: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV---LMKQEHREEI 710

Query: 710 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSC 743
           + +      S    P+P P  +Q+   P   S C
Sbjct: 711 DLS------SVPSLPVPHPAQTQR---PSSDSGC 735


>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 2 [Homo sapiens]
          Length = 1068

 Score =  561 bits (1446), Expect = e-160
 Identities = 355/754 (47%), Positives = 454/754 (60%), Gaps = 71/754 (9%)

Query: 24  GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
           GE   PAP   G+ + A+ E    AS  +    P P+  +T L  P H L + +  + P 
Sbjct: 19  GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77

Query: 83  ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
               S   Y    +   + Y        P G P   E P I+ITS     H   +    D
Sbjct: 78  FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130

Query: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYESNYSYPY 197
           +++ D        PS   L LP   +YR+ S   SPASS+SSRS  S+ASS ES  S+ Y
Sbjct: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCES-LSHIY 189

Query: 198 ----------------ASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPS 239
                            SP TSP  SP  C   +T   + G    L       SPR SP 
Sbjct: 190 DDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPC 242

Query: 240 TSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGS 290
            SPR+SVT+E+WL  R     SSRP SPC KR++S    +  Y    SPHHSP PSP  S
Sbjct: 243 HSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHS 300

Query: 291 PRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKV 350
           PR SVT+D+WL N + +  S +  A+         D    +P+K+RKT+ +Q   +  K+
Sbjct: 301 PRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKL 355

Query: 351 EPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMS 409
           E   +D GS  P  + + +D    Q+  K   C DQ+L+VP  P+ W+KPKP     + +
Sbjct: 356 ELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRT 414

Query: 410 PTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLEN 469
            +LP LDW LP+H G  EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E 
Sbjct: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473

Query: 470 EPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRA 529
           +P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533

Query: 530 VIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQ 589
            IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQ
Sbjct: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593

Query: 590 RSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRD 649
           RSAQELP +EK S +S  V GG +MV++G NFL +SK+IF+EK  DG   WE+E K  R+
Sbjct: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653

Query: 650 LCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDY 709
            C+   +V+E+PP+ N  +T+ V V FY+CNGKRK+SQ QRFTY P    ++K E  ++ 
Sbjct: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV---LMKQEHREEI 710

Query: 710 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSC 743
           + +      S    P+P P  +Q+   P   S C
Sbjct: 711 DLS------SVPSLPVPHPAQTQR---PSSDSGC 735


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score =  427 bits (1099), Expect = e-119
 Identities = 330/845 (39%), Positives = 405/845 (47%), Gaps = 143/845 (16%)

Query: 41  EEEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAG 99
           E   YG A   +  P  P P  HS  P P  +         P         +   GGP G
Sbjct: 113 EPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGGPGG 163

Query: 100 YFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP------- 146
               +G     G   LE P I ITS            +N   + D    D  P       
Sbjct: 164 GAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGY 218

Query: 147 --------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYA 198
                    +  SPS  + SL S   + D S    A   +     SE +   S +     
Sbjct: 219 REAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGLG-- 275

Query: 199 SPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL------ 252
               SP  SP  SP+   PE+ +       +L G        SP     E+SWL      
Sbjct: 276 ----SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLSAPG 317

Query: 253 -GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWLGNT 304
               S RPASPC KR+YS +G     SP  S   S       P   P + +  D      
Sbjct: 318 PTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGP 377

Query: 305 TQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPA 364
             Y  +                  + +P K+R+T+ EQ  ++    EP   + G  P  A
Sbjct: 378 FDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGA 421

Query: 365 DFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALDWQL 419
           +   E  +     RK      YLAVP  P  W+K +     P+  TS     LP LDW L
Sbjct: 422 E---ESVAPPGGSRKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLDWPL 473

Query: 420 PSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIG 479
           PS     ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+FIG
Sbjct: 474 PSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQMFIG 532

Query: 480 TADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKL 539
           TAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGILKL
Sbjct: 533 TADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKL 592

Query: 540 RNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVE 599
           RNSDIELRKGETDIGRKNTRVRLVFRVHVPQ  G+ +S+Q AS PIECSQRSAQELP VE
Sbjct: 593 RNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVE 652

Query: 600 KQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVE 659
             S  +  V GG+++VL+G NFL DSKV+F+E+ PDG   WE EA  +R      +L + 
Sbjct: 653 AYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLT 712

Query: 660 IPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE----PAPTC 715
           +P + N+R++ PV V FYV NG+RKRS  Q F +LP    I K EP  D      P+ + 
Sbjct: 713 VPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGFPSASA 769

Query: 716 GP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPGVSPKL 768
            P       SP   PY S     P   +  L  GF     P  PQ        P   P L
Sbjct: 770 TPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPSYRPGL 825

Query: 769 HDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GSPGQPP 818
                   T G A P              PAV  +PRP  + P          G P  PP
Sbjct: 826 RMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGLPFSPP 871

Query: 819 PALLP 823
               P
Sbjct: 872 APFRP 876


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score =  427 bits (1099), Expect = e-119
 Identities = 330/845 (39%), Positives = 405/845 (47%), Gaps = 143/845 (16%)

Query: 41  EEEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAG 99
           E   YG A   +  P  P P  HS  P P  +         P         +   GGP G
Sbjct: 50  EPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGGPGG 100

Query: 100 YFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP------- 146
               +G     G   LE P I ITS            +N   + D    D  P       
Sbjct: 101 GAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGY 155

Query: 147 --------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYA 198
                    +  SPS  + SL S   + D S    A   +     SE +   S +     
Sbjct: 156 REAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGLG-- 212

Query: 199 SPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL------ 252
               SP  SP  SP+   PE+ +       +L G        SP     E+SWL      
Sbjct: 213 ----SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLSAPG 254

Query: 253 -GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWLGNT 304
               S RPASPC KR+YS +G     SP  S   S       P   P + +  D      
Sbjct: 255 PTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGP 314

Query: 305 TQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPA 364
             Y  +                  + +P K+R+T+ EQ  ++    EP   + G  P  A
Sbjct: 315 FDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGA 358

Query: 365 DFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALDWQL 419
           +   E  +     RK      YLAVP  P  W+K +     P+  TS     LP LDW L
Sbjct: 359 E---ESVAPPGGSRKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLDWPL 410

Query: 420 PSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIG 479
           PS     ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+FIG
Sbjct: 411 PSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQMFIG 469

Query: 480 TADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKL 539
           TAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGILKL
Sbjct: 470 TADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKL 529

Query: 540 RNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVE 599
           RNSDIELRKGETDIGRKNTRVRLVFRVHVPQ  G+ +S+Q AS PIECSQRSAQELP VE
Sbjct: 530 RNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVE 589

Query: 600 KQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVE 659
             S  +  V GG+++VL+G NFL DSKV+F+E+ PDG   WE EA  +R      +L + 
Sbjct: 590 AYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLT 649

Query: 660 IPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE----PAPTC 715
           +P + N+R++ PV V FYV NG+RKRS  Q F +LP    I K EP  D      P+ + 
Sbjct: 650 VPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGFPSASA 706

Query: 716 GP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPGVSPKL 768
            P       SP   PY S     P   +  L  GF     P  PQ        P   P L
Sbjct: 707 TPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPSYRPGL 762

Query: 769 HDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GSPGQPP 818
                   T G A P              PAV  +PRP  + P          G P  PP
Sbjct: 763 RMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGLPFSPP 808

Query: 819 PALLP 823
               P
Sbjct: 809 APFRP 813



 Score = 30.4 bits (67), Expect = 7.0
 Identities = 52/211 (24%), Positives = 74/211 (35%), Gaps = 55/211 (26%)

Query: 646 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTY-LPANVPIIKTE 704
           TD D   P       PP+ +     P   + Y+  G         F Y +P   P  +T 
Sbjct: 711 TDMDFSPPR------PPYPSYPHEDPACETPYLSEG---------FGYGMPPLYP--QTG 753

Query: 705 PTDDYEPAPTCGPVSQG---------LSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS 755
           P   Y P     P ++G         +S LPRP+ S          S  +   PP P R 
Sbjct: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRP 813

Query: 756 TLMPAAP---GVSPKLHDLSPA---AYTKGVASPGHCH-LGLPQP----AGEAPAVQD-- 802
             +PA+P   G  P   D+ P     Y K    PG+    G P+      G +   +D  
Sbjct: 814 PPLPASPPLEGPFPSQSDVHPLPAEGYNK--VGPGYGPGEGAPEQEKSRGGYSSGFRDSV 871

Query: 803 -------------VPRPVATHPGSPGQPPPA 820
                        + R ++  P  PG+ PPA
Sbjct: 872 PIQGITLEEVSEIIGRDLSGFPAPPGEEPPA 902


>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
           sapiens]
          Length = 1455

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 248

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 249 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 306

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 307 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 366

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 367 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 423

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 424 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 467


>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
           sapiens]
          Length = 1531

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 267 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 324

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 325 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 382

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 383 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 442

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 443 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 499

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 500 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 543



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 47/205 (22%), Positives = 68/205 (33%), Gaps = 39/205 (19%)

Query: 47  YASSNVSPALP----LPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPA 98
           Y+  +V   LP    LP +  T  A          G  PPA    D  S   ++  GG  
Sbjct: 22  YSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGAC 81

Query: 99  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEV----------------- 141
             F +S           +S  +++ SC      +N+   + ++                 
Sbjct: 82  SSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTV 141

Query: 142 -------EDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYS 194
                  ED+L +S+ S       L S     + SC        S   N   SSY  N  
Sbjct: 142 LYISPPPEDLLDNSRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTE 196

Query: 195 YPYASPQTSPWQSPCVSPKTTDPEE 219
            P  S + +P Q P V  K  D EE
Sbjct: 197 VPRKSRKRNPKQRPGV--KRRDCEE 219


>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
           sapiens]
          Length = 1548

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 342

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 343 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 400

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 401 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 460

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 461 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 517

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 518 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 44/192 (22%), Positives = 63/192 (32%), Gaps = 35/192 (18%)

Query: 56  LPLPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDG 111
           L LP +  T  A          G  PPA    D  S   ++  GG    F +S       
Sbjct: 53  LQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYS 112

Query: 112 APALESPRIEITSCLGLYHNNNQFFHDVEV------------------------EDVLPS 147
               +S  +++ SC      +N+   + ++                        ED+L +
Sbjct: 113 TSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDN 172

Query: 148 SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 207
           S+ S       L S     + SC        S   N   SSY  N   P  S + +P Q 
Sbjct: 173 SRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQR 227

Query: 208 PCVSPKTTDPEE 219
           P V  K  D EE
Sbjct: 228 PGV--KRRDCEE 237


>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
           sapiens]
          Length = 1549

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 342

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 343 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 400

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 401 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 460

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 461 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 517

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 518 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 44/192 (22%), Positives = 63/192 (32%), Gaps = 35/192 (18%)

Query: 56  LPLPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDG 111
           L LP +  T  A          G  PPA    D  S   ++  GG    F +S       
Sbjct: 53  LQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYS 112

Query: 112 APALESPRIEITSCLGLYHNNNQFFHDVEV------------------------EDVLPS 147
               +S  +++ SC      +N+   + ++                        ED+L +
Sbjct: 113 TSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDN 172

Query: 148 SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 207
           S+ S       L S     + SC        S   N   SSY  N   P  S + +P Q 
Sbjct: 173 SRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQR 227

Query: 208 PCVSPKTTDPEE 219
           P V  K  D EE
Sbjct: 228 PGV--KRRDCEE 237


>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
           sapiens]
          Length = 1455

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 248

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 249 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 306

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 307 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 366

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 367 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 423

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 424 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 467


>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 2 [Homo sapiens]
          Length = 548

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 108/446 (24%), Positives = 163/446 (36%), Gaps = 64/446 (14%)

Query: 423 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 476
           SGPY   IE   +   R  Y+ EG S G++           HP ++++GY     + + L
Sbjct: 17  SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76

Query: 477 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 530
                 D   RPH     H + GK      +EA L   + +       I  + +  +   
Sbjct: 77  ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129

Query: 531 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPIECSQ 589
           I    I    N   E ++G+ D+      VRL F+V V  PSGR L L  V S+PI  ++
Sbjct: 130 IS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPIFDNR 184

Query: 590 R-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK-TD 647
             +  EL +          + G +  +L      +D +V F          WE     + 
Sbjct: 185 APNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQ 238

Query: 648 RDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIKTE-- 704
            D+ +  ++V   PP+ +  + +PV VS  +     R+ S+   F YLP      + E  
Sbjct: 239 ADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEK 298

Query: 705 -------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLAMPPD 739
                              PTD   P       S+  +      P P P+ S    +  D
Sbjct: 299 RKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYD 358

Query: 740 PSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPA 799
               +V       Q S L PA P V P+    +PA     V++       +P  A   P 
Sbjct: 359 EFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAPGPPQ 416

Query: 800 VQDVPRPVATHPGSPGQPPPALLPQQ 825
               P P  T  G  G    ALL  Q
Sbjct: 417 AVAPPAPKPTQAGE-GTLSEALLQLQ 441


>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 1 [Homo sapiens]
          Length = 551

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 108/450 (24%), Positives = 166/450 (36%), Gaps = 69/450 (15%)

Query: 423 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 476
           SGPY   IE   +   R  Y+ EG S G++           HP ++++GY     + + L
Sbjct: 17  SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76

Query: 477 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 530
                 D   RPH     H + GK      +EA L   + +       I  + +  +   
Sbjct: 77  ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129

Query: 531 IDCAGILKLRNSD----IELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPI 585
           I     ++  N+     IE ++G+ D+      VRL F+V V  PSGR L L  V S+PI
Sbjct: 130 ISQR--IQTNNNPFQVPIEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPI 183

Query: 586 ECSQR-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEA 644
             ++  +  EL +          + G +  +L      +D +V F          WE   
Sbjct: 184 FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARG 237

Query: 645 K-TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIK 702
             +  D+ +  ++V   PP+ +  + +PV VS  +     R+ S+   F YLP      +
Sbjct: 238 SFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHR 297

Query: 703 TE---------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLA 735
            E                     PTD   P       S+  +      P P P+ S    
Sbjct: 298 IEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLST 357

Query: 736 MPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAG 795
           +  D    +V       Q S L PA P V P+    +PA     V++       +P  A 
Sbjct: 358 INYDEFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAP 415

Query: 796 EAPAVQDVPRPVATHPGSPGQPPPALLPQQ 825
             P     P P  T  G  G    ALL  Q
Sbjct: 416 GPPQAVAPPAPKPTQAGE-GTLSEALLQLQ 444


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 130/535 (24%), Positives = 171/535 (31%), Gaps = 114/535 (21%)

Query: 7   PVPSKFPL----GPAAAVFGRGE--TLGPAPRA-------GGTMKSAEEEHYGYASSNVS 53
           P PS  P     GP  +V    E  T  P+P A       GG  + A       A+   S
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242

Query: 54  PALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAA-----LDGGPAGYFLSSG 105
           PA   P+A  T  AP H  Q    G   + PP   P    AA     L   P      S 
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302

Query: 106 HTRPDGAPALE-------SPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSP------ 152
              P   P+L+       +P  + T+ LG      Q  H       LPS   SP      
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLG--SPTLQATH-----SFLPSPPLSPLATPPP 355

Query: 153 -STATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQ----- 206
            +   L+LP L+A   P    P S L++ S  +  +        P++ P + P Q     
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415

Query: 207 --SPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCN 264
             SP VSP  T P +  P  L A  L   P  SP  SP  S +      A     A P  
Sbjct: 416 PASPPVSPSATPPSQA-PPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPLQ 472

Query: 265 KRKYSLNGRQPPYSPHHSPTPSPHG--SPRVSVTDDSWLGNTTQYTSSAIVAAINALTTD 322
             K       PP +P    TP      SP  S    +    +     S +          
Sbjct: 473 LAK------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526

Query: 323 SSLDLGDGVPVKSRKTTLEQP--------------PSVALKVEPVGEDLGSPPPP----- 363
            +  L    P      TL+ P              P + L + P     G PPPP     
Sbjct: 527 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSPS 581

Query: 364 --------------ADFAPEDYSSFQHIRKGGFC-----DQYLAVPQHPYQWAKPKPLSP 404
                         A   PE+   +    +GG       D  LA   HP  W++  P  P
Sbjct: 582 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA-CHPAAWSR-GPAPP 639

Query: 405 TSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHP 459
            ++       L W   +  G  +    +         YETEG   A  A     P
Sbjct: 640 LAFRGAPGAPLPWPPATGPGSADGLCTI---------YETEGPESATPAPGALDP 685



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 20/114 (17%)

Query: 712 APTCGPVSQGLSPL--PRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLH 769
           AP   P S  LSPL  P P     LA+       L A F P P      P +P  SP + 
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASPPV- 421

Query: 770 DLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLP 823
             SP+A     A P             AP +Q  P P A+ P SP   PP   P
Sbjct: 422 --SPSATPPSQAPPSLA----------APPLQVPPSPPASPPMSPSATPPPQAP 463



 Score = 38.1 bits (87), Expect = 0.034
 Identities = 40/134 (29%), Positives = 51/134 (38%), Gaps = 6/134 (4%)

Query: 695 PANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRP-YYSQQLAMPPDPSSCLVAGFPPCPQ 753
           P+  P     P+    P+P   P SQ  + L  P   +    +P  P S L    P  P 
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359

Query: 754 RSTLMP-AAPGVSPKLHDLSPAAYTKGVASPGHCHLGL---PQPAGEAPAVQDVPRPVAT 809
              L P  AP   P    LSP A T    +P    + L   P     +P VQ    P A+
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLA-TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418

Query: 810 HPGSPGQPPPALLP 823
            P SP   PP+  P
Sbjct: 419 PPVSPSATPPSQAP 432



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 37/116 (31%), Positives = 42/116 (36%), Gaps = 12/116 (10%)

Query: 713 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAG---FPPCPQRSTLMPAAPGVSPKLH 769
           P   PV    SP   P  S     P      L A     PP P      PA+P +SP   
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP------PASPPMSPSAT 457

Query: 770 DLSPAAYTKGVASPGHCHLGLPQ--PAGEAPAVQDVPRPVATHPGSPGQPPPALLP 823
              P A     A P       PQ  PA   P +Q +P P A+ PG     P A LP
Sbjct: 458 P-PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 1/115 (0%)

Query: 705 PTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGV 764
           P+    P+P+  P  Q L   P    SQ       P+      F P P  S L    P  
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357

Query: 765 SPKLHDLSPAAYTKGVASPGHCHLGLPQP-AGEAPAVQDVPRPVATHPGSPGQPP 818
            P L      A     ASP    L  P P A  A AV  +  P +  P  P Q P
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 33/122 (27%), Positives = 44/122 (36%), Gaps = 13/122 (10%)

Query: 703 TEPTDDYEPAPTCG-----PVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTL 757
           TEP+      P+ G     P S+ LS    P  S   + P    +      P  P+   L
Sbjct: 209 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 268

Query: 758 MPAAPG-VSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQ 816
               P  V+P   D +PA      +SP      L  P+  AP     P  + T P  P  
Sbjct: 269 QALRPPQVTPPRKDAAPALGPLS-SSP------LATPSPSAPPSPSAPPSLQTLPSPPAT 321

Query: 817 PP 818
           PP
Sbjct: 322 PP 323


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 86/312 (27%), Positives = 119/312 (38%), Gaps = 64/312 (20%)

Query: 7   PVPSKFPL----GPAAAVFGRGE--TLGPAPRA-------GGTMKSAEEEHYGYASSNVS 53
           P PS  P     GP  +V    E  T  P+P A       GG  + A       A+   S
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 54  PALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYFLSSGHTRPD 110
           PA   P+A  T  AP H  Q    G   + PP   P    AA   GP     SS    P 
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS---SSPLATPS 308

Query: 111 GAPALES---PRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRD 167
            + AL+S   P +  T      H+++      ++   LP +  SPS      PSL+    
Sbjct: 309 PSAALQSQAPPTLPATP-----HSSSL---TCQLATPLPLAPPSPSAP----PSLQTLPS 356

Query: 168 PSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPR-GLG 226
           P    PA+  S  + +  + + ++ +S+           SP +SP  T P +  P   L 
Sbjct: 357 P----PATPPSQATTSLGSPTLQATHSF---------LPSPPLSPLATPPPQAPPALALP 403

Query: 227 ACTLLGSPRHSPSTSPRASVTEES-------WLGARSSRPASPCNKRKYSLNGRQPPYSP 279
                 SP  SP  SP A+ + ++        L A  S P SP           Q P+SP
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP---------PVQAPFSP 454

Query: 280 HHSPTPSPHGSP 291
             SP  SP  +P
Sbjct: 455 PASPPVSPSATP 466



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 20/114 (17%)

Query: 712 APTCGPVSQGLSPL--PRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLH 769
           AP   P S  LSPL  P P     LA+       L A F P P      P +P  SP + 
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASPPV- 460

Query: 770 DLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLP 823
             SP+A     A P             AP +Q  P P A+ P SP   PP   P
Sbjct: 461 --SPSATPPSQAPPSLA----------APPLQVPPSPPASPPMSPSATPPPQAP 502



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 43/140 (30%), Positives = 53/140 (37%), Gaps = 6/140 (4%)

Query: 689 QRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRP-YYSQQLAMPPDPSSCLVAG 747
           Q  T LP   P     P+    P+P   P SQ  + L  P   +    +P  P S L   
Sbjct: 333 QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 392

Query: 748 FPPCPQRSTLMP-AAPGVSPKLHDLSPAAYTKGVASPGHCHLGL---PQPAGEAPAVQDV 803
            P  P    L P  AP   P    LSP A T    +P    + L   P     +P VQ  
Sbjct: 393 PPQAPPALALPPLQAPPSPPASPPLSPLA-TPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451

Query: 804 PRPVATHPGSPGQPPPALLP 823
             P A+ P SP   PP+  P
Sbjct: 452 FSPPASPPVSPSATPPSQAP 471



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 37/116 (31%), Positives = 42/116 (36%), Gaps = 12/116 (10%)

Query: 713 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAG---FPPCPQRSTLMPAAPGVSPKLH 769
           P   PV    SP   P  S     P      L A     PP P      PA+P +SP   
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP------PASPPMSPSAT 496

Query: 770 DLSPAAYTKGVASPGHCHLGLPQ--PAGEAPAVQDVPRPVATHPGSPGQPPPALLP 823
              P A     A P       PQ  PA   P +Q +P P A+ PG     P A LP
Sbjct: 497 P-PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 19/127 (14%)

Query: 710 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS--TLMPAAPGVSPK 767
           + AP  GP+S      P P  + Q   PP   +   +    C   +   L P +P   P 
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS 350

Query: 768 LHDL------SPAAYTKGVASP----GHCHLGLP------QPAGEAPAVQDVPRPVATHP 811
           L  L       P+  T  + SP     H  L  P       P  +AP    +P P+   P
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP-PLQAPP 409

Query: 812 GSPGQPP 818
             P  PP
Sbjct: 410 SPPASPP 416



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 61/276 (22%), Positives = 91/276 (32%), Gaps = 58/276 (21%)

Query: 9   PSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAP 68
           P+  PL P A          P+P+A     +A   H   A  +  P+ P+    S   +P
Sbjct: 412 PASPPLSPLAT---------PSPQA----PNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458

Query: 69  CHNLQTSTPGIIPPADHPSGYGA----ALDGGPAGYFLSSGHTRPDGAPA-LESPRIEIT 123
                  +P   PP+  P    A         PA   +S   T P  AP  L +P +++ 
Sbjct: 459 -----PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513

Query: 124 SCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSC-------LSPASS 176
                                 P  +  P+ AT   P L+A   P          SP++S
Sbjct: 514 K---------------------PPPQAPPALAT---PPLQALPSPPASFPGQAPFSPSAS 549

Query: 177 LSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVS----PKTTDPEEGFPRGLGACTLLG 232
           L      +         + P      SP  SP +     P T  P+           L  
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609

Query: 233 SPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKY 268
            P   PS SP ++++     G  SS  ++P   R Y
Sbjct: 610 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 37/116 (31%), Positives = 52/116 (44%), Gaps = 11/116 (9%)

Query: 709 YEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKL 768
           + PAP   P + G+ P     +     + P PS+ +       PQ   + PAAP V P+ 
Sbjct: 337 HPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVH------PQAPGVHPAAPAVHPQA 390

Query: 769 HDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDV-PRPVATHPGSPGQPPPALLP 823
             + P A      +PG  H   PQP G  P+   V P+P   HP +PG  PP  +P
Sbjct: 391 PGVHPPAPGMHPQAPG-VH---PQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMP 442



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/127 (32%), Positives = 51/127 (40%), Gaps = 9/127 (7%)

Query: 694 LPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQ 753
           LPA  P +K  P       P   P+ + L P P       L +PP P +      PP P 
Sbjct: 223 LPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPP----PGGLPLPPMPPTGPAPSGPPGPP 278

Query: 754 RSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGS 813
           +  L P APGV P    + P A      +PG   +  P P    PA    P     HP +
Sbjct: 279 Q--LPPPAPGVHPPAPVVHPPASGVHPPAPG---VHPPAPGVHPPAPGVHPPTSGVHPPA 333

Query: 814 PGQPPPA 820
           PG  PPA
Sbjct: 334 PGVHPPA 340


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 47/172 (27%), Positives = 65/172 (37%), Gaps = 23/172 (13%)

Query: 130  HNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSY 189
            HN+  F+ +         + R PS  T   PS   +R PS  S  SSL  R  +    S+
Sbjct: 1539 HNHPSFYRE--------RTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSH 1590

Query: 190  ESNYSYPYASPQTSPWQSPCVSPKTTDPEEG----FPRGLGACTLLG------SPRHSPS 239
             S     ++SP    W+SP      + PE        RGL + +            HSPS
Sbjct: 1591 CSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPS 1650

Query: 240  TSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSP 291
                 S +E S   +   R  SP  +     + R P    H SP+   H SP
Sbjct: 1651 ERSHRSPSERSHRSSSERRHRSPSQR-----SHRGPSERSHCSPSERRHRSP 1697



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 38/144 (26%), Positives = 48/144 (33%), Gaps = 19/144 (13%)

Query: 148  SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 207
            S R PS  +   PS   +R PS  S       R  +    S+ S     + SP      S
Sbjct: 1677 SHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHS 1736

Query: 208  PCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRK 267
            P      +  E                 HSPS     S +E S       R  SP  +R 
Sbjct: 1737 PSERSHHSPSERR--------------HHSPSERSHCSPSERSHCSPSERRHRSPSERRH 1782

Query: 268  YSLNGRQPPYSPHHSPTPSPHGSP 291
            +S     P    HHSP+   H SP
Sbjct: 1783 HS-----PSEKSHHSPSERSHHSP 1801



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 39/148 (26%), Positives = 49/148 (33%), Gaps = 19/148 (12%)

Query: 148  SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 207
            S RS S      PS  ++R PS  S  S    R  +    S+       + SP     +S
Sbjct: 1661 SHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRS 1720

Query: 208  PCVSPKTTDPEEGFPRGLGACTLLGSP----RHSPSTSPRASVTEESWLGARSSRPASPC 263
            P      +  E              SP     HSPS     S +E S          SP 
Sbjct: 1721 PARRSHRSPSERSHH----------SPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770

Query: 264  NKRKYSLNGRQPPYSPHHSPTPSPHGSP 291
             +R      R P    HHSP+   H SP
Sbjct: 1771 ERRH-----RSPSERRHHSPSEKSHHSP 1793


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 42/129 (32%), Positives = 49/129 (37%), Gaps = 23/129 (17%)

Query: 708 DYEPAPTC-GPVSQGL-SPLPRPYYSQQLAMPPD--PSSCLVAGFPPCPQRSTLMPAAPG 763
           D  P P+   PV   L S LP P      + PP   P   L  G PP      + P A G
Sbjct: 213 DAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAG 272

Query: 764 VSPKLHDLSPAAYTKGVASPGHCHL--------GLPQPAGEAPAV-----QDVPRPVATH 810
             P      P+A T G   PGH H         G+P P      +       +  P A  
Sbjct: 273 HGP------PSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGP 326

Query: 811 PGSPGQPPP 819
           PGS GQPPP
Sbjct: 327 PGSGGQPPP 335



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 9/101 (8%)

Query: 195 YPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGA 254
           +P+A P  S  Q P   P+   P  G P   G   +   PR  P  SP          G 
Sbjct: 321 HPHAGPPGSGGQPP---PR---PPPGMPHP-GPPPMGMPPRGPPFGSPMGHPGPMPPHGM 373

Query: 255 RSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSV 295
           R   P  P     Y+   R PPY     P P P  +PR  V
Sbjct: 374 RGPPPLMP--PHGYTGPPRPPPYGYQRGPLPPPRPTPRPPV 412


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 49/192 (25%), Positives = 77/192 (40%), Gaps = 24/192 (12%)

Query: 638 HVWEMEAKTDRDLCKPNSLVVEIPP--FRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
           H W    +  +D+C   S   + PP  FRN  + +        C  + K ++  +     
Sbjct: 552 HRWRGGCEERKDVCI--STDDDCPPKTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKK 609

Query: 696 ANVPII-KTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQR 754
            N+  + +  P +D++       +   L P+     +QQ A+PP P+S  +   PP P  
Sbjct: 610 LNISSLSQLSPPNDHKD------IHAALQPMEGMASNQQKALPPPPAS--IPPPPPLPSG 661

Query: 755 -STLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP--AGEAPAVQDVPRPVATHP 811
             +L PA P        + P +    +  P      LP P  AG  P     P P +  P
Sbjct: 662 LGSLSPAPP--------MPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAP 713

Query: 812 GSPGQPPPALLP 823
            +PG PPPA  P
Sbjct: 714 PNPGGPPPAPPP 725


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 71/262 (27%), Positives = 91/262 (34%), Gaps = 66/262 (25%)

Query: 57  PLPTAH---STLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAP 113
           PL T H      PAPC      +P   PP + PS               S     P   P
Sbjct: 552 PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS---------------SIATPPPQAPP 596

Query: 114 ALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSP-------STATLSLPSLEAYR 166
           AL SP ++                       LPS   SP       +   L+LP L+A  
Sbjct: 597 ALASPPLQ----------------------GLPSPPLSPLATPPPQAPPXLALPPLQAPP 634

Query: 167 DPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQ-------SPCVSPKTTDPEE 219
            P    P S L++ S  +  +        P++ P + P Q       SP VSP  T P +
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694

Query: 220 GFPRGLGACTLL--GSPRHSPSTSPRASVTEES-------WLGARSSRPASPCNKRKYSL 270
             P  L A  L    SP  SP  SP A+   ++        L    S PASP      + 
Sbjct: 695 A-PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753

Query: 271 NGRQPPY--SPHHSPTPSPHGS 290
             R PP   +P     PSP  S
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPAS 775



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 118/448 (26%), Positives = 156/448 (34%), Gaps = 93/448 (20%)

Query: 7   PVPSKFPL----GPAAAVFGRGE--TLGPAPRA-------GGTMKSAEEEHYGYASSNVS 53
           P PS  P     GP  +V    E  T  P+P A       GG  + A       A+   S
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 54  PALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYFLSS---GHT 107
           PA   P+A  T  AP H  Q    G   + PP   P    AA   GP    LSS      
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP----LSSSPLATP 307

Query: 108 RPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRD 167
            P G  A   P                           P +  +P  AT  LP       
Sbjct: 308 SPSGTKARPVPP--------------------------PDNAATPLPAT--LPPSPPLAT 339

Query: 168 PSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSP---------CVSPKTTDPE 218
           P  L+P S  +  S  +  S   +  S    S  T P Q+P          V    T P 
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399

Query: 219 EGFP------RGLGACTLLGSP----RHSPST-SPR---ASVTEESWLGARSSRPASPCN 264
              P        L A T LGSP     HS  T SPR   AS+T  S     S+ P SP  
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS--RPASTPPDSPPL 457

Query: 265 KRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAI--NALTTD 322
           +   SL    PP     SP  SP  SP +++     L +   ++  A ++++    L T 
Sbjct: 458 QAPLSLPA-SPPLQTSLSPAVSPLSSP-LTIHPLQALSSLASHSPQAPLSSLIMPPLETQ 515

Query: 323 SSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGF 382
           SSL             +L+ PP+ +L   P+       PPP   A    ++  H+     
Sbjct: 516 SSL----------APPSLQTPPA-SLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPP- 562

Query: 383 CDQYLAVPQHPYQWAKPKPLSPTSYMSP 410
           C     +   P     P P +P+S  +P
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATP 590



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 43/135 (31%), Positives = 50/135 (37%), Gaps = 31/135 (22%)

Query: 712 APTCGPVSQGLSPL--PRPYYSQQLAM-------PPDPSSCLVAGFPPCPQRSTLMPAAP 762
           AP   P S  LSPL  P P     LA+        P PS  + A F P        PA+P
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP--------PASP 683

Query: 763 GVSPKLHDLSPAAYTKGV----------ASPGHCHLGLPQPAGE----APAVQDVPRPVA 808
            VSP     S A  +             ASP       P P       AP +Q  P P A
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743

Query: 809 THPGSPGQPPPALLP 823
           + P SP   PP  +P
Sbjct: 744 SPPMSPSATPPPRVP 758



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 37/121 (30%), Positives = 50/121 (41%), Gaps = 12/121 (9%)

Query: 710 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSC--LVAGFPPCPQRST---LMPAAPGV 764
           + AP  GP+S      P P  ++   +PP  ++   L A  PP P  +T   L P +P  
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350

Query: 765 SPKLHDL-SPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP-GSPG-QPPPAL 821
            P L  L SP A     A P         P    P++Q +P     H   SP  Q PP+ 
Sbjct: 351 PPSLQTLPSPPATPPSQAPPSM----TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406

Query: 822 L 822
           L
Sbjct: 407 L 407



 Score = 37.0 bits (84), Expect = 0.075
 Identities = 43/150 (28%), Positives = 49/150 (32%), Gaps = 23/150 (15%)

Query: 695 PANVPIIKTEPTDDYEPA----PTCGPVSQGLSPL--PRPYYSQQLAMPPDPSSCLVAGF 748
           P   P     P     PA    P  G  S  LSPL  P P     LA+PP  +       
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639

Query: 749 PPCPQRSTLMPAAPGV---------------SPKLHDLSPAAYTKGVASPGHCHLGLPQP 793
           PP    +T  P AP                  P     SP A      SP         P
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPP 697

Query: 794 AGEAPAVQDVPRPVATHPGSPGQPPPALLP 823
           +  AP +Q  P P A+ P SP   PP   P
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAP 727



 Score = 36.6 bits (83), Expect = 0.098
 Identities = 37/135 (27%), Positives = 53/135 (39%), Gaps = 12/135 (8%)

Query: 695 PANVPIIKTEPTDDYEPAPTCGP-VSQGLSPLPR---PYYSQQLAMPPDPSSCLVAGFPP 750
           P+  P     P     P+P   P +S   +P P+   P  +  L +PP P +      PP
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS-----PP 746

Query: 751 CPQRSTLMPAAPGV--SPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVA 808
               +T  P  P +  +P L  + P+       SP         PA   P +Q +P P A
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQ-VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805

Query: 809 THPGSPGQPPPALLP 823
           + PG     P A LP
Sbjct: 806 SFPGQAPFSPSASLP 820



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 25/163 (15%)

Query: 145 LPSSKRSP---STATLSLPSLEAYRDPS---CLSPASSLSSRSCNSEASSYESNYSYP-- 196
           LPS    P   ++A L+ P LE    P+     +P S L++    + +S        P  
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597

Query: 197 YASPQTSPWQSPCVSPKTTDPEEGFPR-GLGACTLLGSPRHSPSTSPRASVTEES----- 250
            ASP      SP +SP  T P +  P   L       SP  SP  SP A+ + ++     
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657

Query: 251 --WLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSP 291
              L A  S P SP           Q P+SP  SP  SP  +P
Sbjct: 658 VHLLQAPFSPPPSP---------PVQAPFSPPASPPVSPSATP 691



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 31/109 (28%), Positives = 40/109 (36%), Gaps = 19/109 (17%)

Query: 713 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS 772
           P   P  +  +P   P  S  LA P  PS       PP    +T +PA    SP L    
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATP-SPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341

Query: 773 PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPAL 821
           P A               P      P++Q +P P AT    P Q PP++
Sbjct: 342 PLA---------------PPSPSAPPSLQTLPSPPAT---PPSQAPPSM 372



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 56/232 (24%), Positives = 76/232 (32%), Gaps = 45/232 (19%)

Query: 214 TTDPEEGFP------RGLGACTLLGSPRHSPSTSPR----------ASVTEESWLGARSS 257
           T+ P  G P      R   A T +G PR +PS  PR          +S +E S     ++
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TT 218

Query: 258 RPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAIN 317
            P+    +R  +  G Q P S   S + +P  SP  S            + S      + 
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278

Query: 318 ALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHI 377
           AL            P K     L    S  L           P PP D A     +    
Sbjct: 279 ALRPPQVTP-----PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA---- 329

Query: 378 RKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSP----TLPALDWQLPSHSGP 425
                      +P  P   A P PL+P S  +P    TLP+     PS + P
Sbjct: 330 ----------TLPPSP-PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 54/185 (29%), Positives = 79/185 (42%), Gaps = 29/185 (15%)

Query: 151 SPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCV 210
           SPS +  S+PS     D    SP++S +S   NS  +S+ ++++   + P  S W SP  
Sbjct: 38  SPSASGASIPS-----DSGWASPSASGASTPSNSGWASFSASWA---SIPSDSGWASPSA 89

Query: 211 SPKTTDPEEGF--PRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKY 268
           S  +T  + G+  P   GA     S   SPS S  AS+    W        ASP      
Sbjct: 90  SWASTPSDSGWASPSASGASIPSDSGWASPSVS-GASIPSAFW--------ASP------ 134

Query: 269 SLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTS-SAIVAAINALTTDSSLDL 327
           S +G     +P  S   SP  S   + +D  W   +  +TS SA  A+ +A    +  D 
Sbjct: 135 SASGAS---TPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDS 191

Query: 328 GDGVP 332
           G   P
Sbjct: 192 GWASP 196



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 46/157 (29%), Positives = 65/157 (41%), Gaps = 10/157 (6%)

Query: 151 SPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYS-YPYASPQTSPWQSPC 209
           SPST+  S PS   +      S  +S SS SC S ++S  S  S   +ASP  S W S  
Sbjct: 202 SPSTSWASSPSDFGWASTPSDSGWAS-SSASCISPSASGASTSSDSGWASPSAS-WVSTS 259

Query: 210 VSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARS-SRPASPCNKRKY 268
            S  +T  + G+     +   + S       S   + +  SW  A S S  +SP   R  
Sbjct: 260 TSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRAS 319

Query: 269 SLN-GRQPPYSPHHSPTPS-----PHGSPRVSVTDDS 299
           +L+      +S   +  PS      H +  VS T DS
Sbjct: 320 TLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDS 356


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/133 (34%), Positives = 49/133 (36%), Gaps = 27/133 (20%)

Query: 705  PTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP-----SSCLVAGFPPCPQRSTLMP 759
            P     P P C PV     PLP PY     A  P P     SS + AGFP          
Sbjct: 899  PNPTPAPPPPCFPVPPP-QPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFP---------- 947

Query: 760  AAP--GVSPKLHDLSPAAYTKGVASPG------HCHLGLPQPAGEAPAVQDVPRPVATHP 811
             AP  G  P+ H     +   G   P       H HL  PQ  G  P     P P A  P
Sbjct: 948  -APRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQS--PYPYAPQP 1004

Query: 812  GSPGQPPPALLPQ 824
            G  GQPPP L  Q
Sbjct: 1005 GVLGQPPPPLHTQ 1017



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 68/258 (26%), Positives = 85/258 (32%), Gaps = 54/258 (20%)

Query: 2    PSTSFPVPSKFPLG-----PAAAVFGRGETLG-PAPRAGGTMKSAEEEHYGYASSNVSPA 55
            P    P P  +P G     PA   F  G   G PAPR G   +   + H   A     P 
Sbjct: 914  PPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQ 973

Query: 56   LPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPAL 115
             PLP  H  L  P        PG++PP    S Y  A   G  G      HT+    PA 
Sbjct: 974  QPLPLQHPHLFPP------QAPGLLPP---QSPYPYAPQPGVLGQPPPPLHTQLYPGPA- 1023

Query: 116  ESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSK-----RSPSTATLSLPSLEAYRDPSC 170
                                      +D LP+        SP       P L     PS 
Sbjct: 1024 --------------------------QDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPST 1057

Query: 171  --LSP-ASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGA 227
              + P A+ L+ R  +S   S  S +  P  +P   P   P   P   +P     RG  A
Sbjct: 1058 RPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVP-PRPPAAEPPPCLRRGAAA 1116

Query: 228  CTLLGS---PRHSPSTSP 242
              LL S    +H  + SP
Sbjct: 1117 ADLLSSSPESQHGGTQSP 1134



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 19/128 (14%)

Query: 711 PAPTCGPVSQGLSPLPRPYYSQQLAMPPDPS------SCLVAGFPPCPQRSTLMPAAPG- 763
           P P   PV+ G +  P P Y+ +L + P  S      S    G  P P  + L  A P  
Sbjct: 808 PGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQ 867

Query: 764 -VSPKL-HDLSPAAYT-KGVASPGHCHL--------GLPQPAGEAPAVQDVPRPVATHPG 812
              P+L   + PA  T   + +P   H           P P    P  Q +P P  T+P 
Sbjct: 868 FSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPY-TYPA 926

Query: 813 SPGQPPPA 820
              QP PA
Sbjct: 927 GAKQPIPA 934



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 12/110 (10%)

Query: 724 PLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDL---------SPA 774
           P PRP   + L    + S  + AG PP   RS  +P      P+L D           P 
Sbjct: 716 PPPRPTAPKPLLPRREESEAVEAGDPPEELRS--LPPDMVAGPRLPDTFLGSATPLHFPP 773

Query: 775 AYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP-GSPGQPPPALLP 823
           +       PG  +L  P P G       + +P A  P   P  P PAL P
Sbjct: 774 SPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYP 823


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,638,612
Number of Sequences: 37866
Number of extensions: 2679372
Number of successful extensions: 11369
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 508
Number of HSP's that attempted gapping in prelim test: 9283
Number of HSP's gapped (non-prelim): 2278
length of query: 825
length of database: 18,247,518
effective HSP length: 111
effective length of query: 714
effective length of database: 14,044,392
effective search space: 10027695888
effective search space used: 10027695888
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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