Guide to the Human Genome
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Search of human proteins with 19923274

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923274 discs large homolog-associated protein 1 isoform
alpha [Homo sapiens]
         (977 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923274 discs large homolog-associated protein 1 isoform alp...  1973   0.0  
gi|51339031 discs large homolog-associated protein 1 isoform bet...  1319   0.0  
gi|38202224 discs large-associated protein 2 [Homo sapiens]           924   0.0  
gi|34335253 disks large-associated protein 4 isoform a [Homo sap...   799   0.0  
gi|122937233 discs, large (Drosophila) homolog-associated protei...   629   e-180
gi|34335251 disks large-associated protein 4 isoform b [Homo sap...   425   e-118
gi|109891938 disks large-associated protein 4 isoform c [Homo sa...   309   7e-84
gi|226371669 discs large homolog 7 isoform b [Homo sapiens]            81   4e-15
gi|226371667 discs large homolog 7 isoform a [Homo sapiens]            81   4e-15
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        41   0.006
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]            40   0.008
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]            40   0.008
gi|55749544 SH3 multiple domains 1 [Homo sapiens]                      40   0.014
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              39   0.024
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]    38   0.041
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]     38   0.041
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            37   0.069
gi|83367077 mucin 16 [Homo sapiens]                                    37   0.090
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            37   0.090
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            37   0.090
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            37   0.090
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    37   0.090
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            37   0.090
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            37   0.090
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            37   0.090
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            37   0.090
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            37   0.090
gi|161019170 mucin 5AC [Homo sapiens]                                  37   0.12 
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       37   0.12 
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    37   0.12 

>gi|19923274 discs large homolog-associated protein 1 isoform alpha
           [Homo sapiens]
          Length = 977

 Score = 1973 bits (5111), Expect = 0.0
 Identities = 977/977 (100%), Positives = 977/977 (100%)

Query: 1   MKGLSGSRSHHHGVTCDSACDSLSHHSDRKPYLLSPVEHHPADHPYYTQRNSFQAECVGP 60
           MKGLSGSRSHHHGVTCDSACDSLSHHSDRKPYLLSPVEHHPADHPYYTQRNSFQAECVGP
Sbjct: 1   MKGLSGSRSHHHGVTCDSACDSLSHHSDRKPYLLSPVEHHPADHPYYTQRNSFQAECVGP 60

Query: 61  FSDPLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFERQLPLSRDGYHT 120
           FSDPLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFERQLPLSRDGYHT
Sbjct: 61  FSDPLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFERQLPLSRDGYHT 120

Query: 121 LQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGKASPDEAQAARYGK 180
           LQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGKASPDEAQAARYGK
Sbjct: 121 LQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGKASPDEAQAARYGK 180

Query: 181 RSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVMTMGRCPDRSASQYFLEAY 240
           RSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVMTMGRCPDRSASQYFLEAY
Sbjct: 181 RSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVMTMGRCPDRSASQYFLEAY 240

Query: 241 NTISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSSTLTVSRAREVYQKASVNMD 300
           NTISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSSTLTVSRAREVYQKASVNMD
Sbjct: 241 NTISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSSTLTVSRAREVYQKASVNMD 300

Query: 301 QAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSD 360
           QAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSD
Sbjct: 301 QAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSD 360

Query: 361 TSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSL 420
           TSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSL
Sbjct: 361 TSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSL 420

Query: 421 DSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALD 480
           DSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALD
Sbjct: 421 DSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALD 480

Query: 481 LPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKK 540
           LPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKK
Sbjct: 481 LPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKK 540

Query: 541 TPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALT 600
           TPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALT
Sbjct: 541 TPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALT 600

Query: 601 AAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAE 660
           AAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAE
Sbjct: 601 AAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAE 660

Query: 661 EPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDN 720
           EPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDN
Sbjct: 661 EPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDN 720

Query: 721 SCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDP 780
           SCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDP
Sbjct: 721 SCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDP 780

Query: 781 LEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQL 840
           LEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQL
Sbjct: 781 LEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQL 840

Query: 841 LMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWK 900
           LMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWK
Sbjct: 841 LMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWK 900

Query: 901 QMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSAT 960
           QMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSAT
Sbjct: 901 QMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSAT 960

Query: 961 ESAESIEIYIPEAQTRL 977
           ESAESIEIYIPEAQTRL
Sbjct: 961 ESAESIEIYIPEAQTRL 977


>gi|51339031 discs large homolog-associated protein 1 isoform beta
           [Homo sapiens]
          Length = 675

 Score = 1319 bits (3414), Expect = 0.0
 Identities = 658/659 (99%), Positives = 659/659 (100%)

Query: 319 QVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLK 378
           +VPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLK
Sbjct: 17  KVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLK 76

Query: 379 ATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRN 438
           ATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRN
Sbjct: 77  ATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRN 136

Query: 439 ESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAI 498
           ESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAI
Sbjct: 137 ESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAI 196

Query: 499 EKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISIT 558
           EKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISIT
Sbjct: 197 EKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISIT 256

Query: 559 AQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHM 618
           AQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHM
Sbjct: 257 AQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHM 316

Query: 619 GNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVG 678
           GNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVG
Sbjct: 317 GNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVG 376

Query: 679 VQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTST 738
           VQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTST
Sbjct: 377 VQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTST 436

Query: 739 VSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLK 798
           VSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLK
Sbjct: 437 VSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLK 496

Query: 799 LLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLN 858
           LLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLN
Sbjct: 497 LLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLN 556

Query: 859 PNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPK 918
           PNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPK
Sbjct: 557 PNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPK 616

Query: 919 KPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977
           KPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL
Sbjct: 617 KPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL 675


>gi|38202224 discs large-associated protein 2 [Homo sapiens]
          Length = 975

 Score =  924 bits (2389), Expect = 0.0
 Identities = 541/1020 (53%), Positives = 673/1020 (65%), Gaps = 88/1020 (8%)

Query: 1   MKGLSGSRSHH---HGVTCDSA----CDSLSHHSD-RKPYLLSPVEHHPADHPYYTQRNS 52
           MKGLSGSR+      G TC  A    C+ L H  D R PYLLSP +  P      + R+S
Sbjct: 1   MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSS 60

Query: 53  FQAECVGP---FSDPLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFER 109
             +ECV       D ++SSTFPR HY+S  + +D+CA+       K NRIPANLLDQFE+
Sbjct: 61  VHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHA--GAKINRIPANLLDQFEK 118

Query: 110 QLPLSRDGYHTLQYKRT--AVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGK 167
           QLPL RDG+HTLQY+RT  A E RS+SPGRIRHLVHSVQKLFTKSHSLEG SK + NG K
Sbjct: 119 QLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNANGTK 178

Query: 168 ASP-----DEAQAARYGKRSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVM 222
           A         A  A++ KRSKSKER+ E K RP  S  WWSSDDNLD D   Y  PS + 
Sbjct: 179 ADGRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMS-SWWSSDDNLDSDST-YRTPSVLN 236

Query: 223 TMGRCPDRSASQYFLEAYNTISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSST 282
                P   A  Y     +   + ++K S+SNNDVKCS C  L ++ D   LK+S+WS T
Sbjct: 237 RHHLGP--VAHCYPDALQSPFGDLSLKTSKSNNDVKCSACEGLALTPDAKYLKRSSWS-T 293

Query: 283 LTVSRAREVYQKASVNMDQAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRM 342
           LTVS+A+E Y+K+S+N+D+ ++  ++    R C YLQVPQDEW GY   GKD+EIPCRRM
Sbjct: 294 LTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQDEWGGYPTGGKDEEIPCRRM 353

Query: 343 RSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQI 402
           RSGSYIKAMGDE+SG+SD+SPK SPK A   E  LK              S    P  + 
Sbjct: 354 RSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLLK--------------SIGQRPLGEH 399

Query: 403 RSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMST------ISQVSEMEV 456
           ++ +YL+A S+V +  SLD   PA    SPKFRSRN+SYMRA+ST      +SQVSE E+
Sbjct: 400 QTQTYLQAASDVPVGHSLD---PAANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEAEI 456

Query: 457 NGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSP 516
           NGQFESVCESVFSE+ESQA++ALDLP  GCFR RSHSY+RAI+ G SQDDEC+ + +  P
Sbjct: 457 NGQFESVCESVFSEVESQAMDALDLP--GCFRTRSHSYLRAIQAGYSQDDECIPMMT--P 512

Query: 517 PRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQ 576
              T+T+R    ST +   T YKKTPPPVPPRTT+KP IS+TAQSSTES QDAY D + Q
Sbjct: 513 SDITSTIR----STAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQ 568

Query: 577 RGDIISQS--GLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATV 634
           R     Q   GL NST+SLDS KA+  A+E A AQ H P SQ     +++V T+     V
Sbjct: 569 RMSPWPQDSRGLYNSTDSLDSNKAMNLALETAAAQRHLPESQ-----SSSVRTSDKAILV 623

Query: 635 TTEDRKKDHFKKNRCLSIGIQVDDAEEP--------------DKTGENKAPSKFQSVGVQ 680
           +    K +   K+RC SIGIQ  D+E P              D   E++   ++ SVGVQ
Sbjct: 624 S----KAEELLKSRCSSIGIQ--DSEFPEHQPYPRSDVETATDSDTESRGLREYHSVGVQ 677

Query: 681 VEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVS 740
           VE+EK   RF RSNSVT AVQADL+  +     + + +     G   ++ S  ++ +  S
Sbjct: 678 VEDEKRHGRFKRSNSVTAAVQADLEL-EGFPGHITTEDKGLQFGSSFQRHSEPSTPTQYS 736

Query: 741 IQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLKLL 800
              +       +  +D+ T  D S LPPPDPW++    D +E  + S C RDG WFLKLL
Sbjct: 737 AVRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPAI-DTVETGRMSPCRRDGSWFLKLL 795

Query: 801 QAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPN 860
            AE  RMEGWC++MERE  EN+L E+ILGKIR+AVGSAQLLM+QKF QF  LC++N++P+
Sbjct: 796 HAETKRMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPS 855

Query: 861 AHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMD-PLDKKERRAPPPVPKK 919
           A PRPTSQDLAG+WDMLQLSIE++SMKFDEL +L+ N+WK M+ P  K+ER+ PPP+PKK
Sbjct: 856 AMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESPERKEERKVPPPIPKK 915

Query: 920 PAKGPAPLIRERSLE--SSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977
           P KG  P+ RE+SL+    QRQEAR+RLMAAKRAAS RQNSA+E A+SIEIYIPEAQTRL
Sbjct: 916 PPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSASERADSIEIYIPEAQTRL 975


>gi|34335253 disks large-associated protein 4 isoform a [Homo
           sapiens]
          Length = 989

 Score =  799 bits (2063), Expect = 0.0
 Identities = 476/1033 (46%), Positives = 623/1033 (60%), Gaps = 100/1033 (9%)

Query: 1   MKGLSGSRSHHHGVTCDSACDSLSHHSDRKPYLLSPVEHHPADHPYYTQRNSFQAECVGP 60
           MKGL  SR  H   + D   + L   +DR PYLLSP E   A    +  +N+   + + P
Sbjct: 1   MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAF-AREARFPGQNTLPGDGLFP 59

Query: 61  FSD--PLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFERQLPLSRDGY 118
            ++  P  SSTFPR HY S  E+ +E        ATK NR+PANLLDQFE+QLP+ RDG+
Sbjct: 60  LNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGF 119

Query: 119 HTLQYKRTAVEHRSDSPGRIRHLVHSVQKL-FTKSHSLEGPSKGSVNGGKASPDEAQAAR 177
            TLQ+ R   + R +SPGRIRHLVHSVQ+L FTK+ SLEG + G V GG  S        
Sbjct: 120 STLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEG-TAGKV-GGNGSKKGGMEDG 177

Query: 178 YGKRSKSKER--RAEPKARP-STSPGWWSSDDNLDGDMCIYHA---PSGVMTMGRCPDRS 231
            G+R+KSKER    EPK R  S   GWWSSDDNLDG+   + +    SG+MT+GR  +RS
Sbjct: 178 KGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERS 237

Query: 232 ASQYFLEAYNTISEQAVKASRSNN---------DVKCSTCANLPVSLDTPLLKKSAWSST 282
             +YF+ AYNTIS   +K +++N              +TC +L V  DT  +K+ +W ST
Sbjct: 238 QPRYFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSW-ST 296

Query: 283 LTVSRAREVYQKASVNMDQAMVKSESCQQERSCQYLQVP--QDEW--TGYTPRGKD---- 334
           LT+S A EV QK S  +D++++KS+SC Q  +  YLQVP    EW  T  +PR  D    
Sbjct: 297 LTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAE 356

Query: 335 DEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISN 394
             IPCRRMRSGSYIKAMGDEDS +S  SPKPSPK AARR+SYL+ATQ SL E        
Sbjct: 357 GPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGE-------- 408

Query: 395 EHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTIS----- 449
           + +P+                  RSLD LD   +L   K  S  E Y     +++     
Sbjct: 409 QSNPR------------------RSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCI 450

Query: 450 ------------------QVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRS 491
                             QV E E++ Q+E+ CES  SE ES A E LDLP+P  FR RS
Sbjct: 451 SQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRS 510

Query: 492 HSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTT 551
           HSY+RAI+ GCSQ+++ VSL+S SPP +T ++   ++   SSC+  YKKTPPPVPPRTT+
Sbjct: 511 HSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTS 570

Query: 552 KPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIH 611
           KPFIS+T QSSTESAQD Y+D Q  + ++ SQSGLSNS++SLDS     +      A   
Sbjct: 571 KPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVA--- 627

Query: 612 GPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAP 671
            PA +            +   T+T+ +   +   K +  SIGIQ           E+  P
Sbjct: 628 -PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGP 686

Query: 672 SKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIE---DNSCPGPMAR 728
                +    E          S+S+++    D D  D  ++S +S E    +  P P + 
Sbjct: 687 KAIDVMAPSSESS------VPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSI 740

Query: 729 QFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSV 788
                   +    Q   N     +  D+ D   + S LPPPDPW+++ +  P E  Q   
Sbjct: 741 SIDAGPRQAPKIAQIKRN----LSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGA 796

Query: 789 CHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQ 848
           C RDG+WFLKLLQAE +R+EGWC QM++E +ENNL E++LGK+ +AVGSAQLLM+QKF Q
Sbjct: 797 CRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQ 856

Query: 849 FRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKK 908
           FR LCE+NLNP+A+PRPT+QDLAGFWD+LQLSIE+ISMKFDEL+ LKAN+W+ ++  +K+
Sbjct: 857 FRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKR 916

Query: 909 --ERRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKRLMAAKRAASVRQNSATESAE 964
             E++ PPPVPKKPAK    + R+++ ++S  QRQEARKRL+AAKRAASVRQNSATESA+
Sbjct: 917 KEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESAD 976

Query: 965 SIEIYIPEAQTRL 977
           SIEIY+PEAQTRL
Sbjct: 977 SIEIYVPEAQTRL 989


>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
           [Homo sapiens]
          Length = 979

 Score =  629 bits (1622), Expect = e-180
 Identities = 433/1073 (40%), Positives = 571/1073 (53%), Gaps = 190/1073 (17%)

Query: 1   MKGLSGSRSHHHGVTCDSACDSLSHHSD-----RKPYLLSPVEHHPADHPYYTQRNSF-- 53
           M+G  G R  H       A  +   H D     R PYLL   E    +  +   R     
Sbjct: 1   MRGYHGDRGSHPR----PARFADQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGH 56

Query: 54  ----------QAECVGPFSDPLA------SSTFPRRHYTSQQELK--DECALVPRTLATK 95
                     +   VGP   P        SSTFPR  Y  Q      ++C   P+     
Sbjct: 57  ISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRM-YPGQGPFDTCEDCVGHPQ--GKG 113

Query: 96  ANRIPANLLDQFERQLPLSRDGYHTLQYKR--------------TAVEHRSDSPGRIRHL 141
           A R+P  LLDQFE+QLP+ +DG+HTL Y+R              TA E RS+SP RIRHL
Sbjct: 114 APRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHL 173

Query: 142 VHSVQKLFTKSHSLEGPSKGSVNGGKASPDEAQA-------------------------- 175
           VHSVQKLF KSHSLE P K   NG KA                                 
Sbjct: 174 VHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHH 233

Query: 176 --ARYGKRSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVMTMGRCPDRSAS 233
             +R+GKRSKSK+R+ + + + + S GWWSSDDNLD D       SG +  GR P     
Sbjct: 234 HQSRHGKRSKSKDRKGDGRHQ-AKSTGWWSSDDNLDSD-------SGFLAGGRPPGEPGG 285

Query: 234 QYFLEAYN-TISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSSTLTVSRAREVY 292
            + LE  + +  + + K     ++ +C  C  + +SLD   +K+SAW  T+ VS+ R+ Y
Sbjct: 286 PFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWH-TMMVSQGRDGY 344

Query: 293 QKASVNMDQAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMG 352
             A     + ++  E+  + R+  YLQVPQD+W GY   GKD EIPCRRMRSGSYIKAMG
Sbjct: 345 PGAGPG--KGLLGPETKAKARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMG 402

Query: 353 DEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVS 412
           DE+SGDSD SPK SPK  ARR              TT + S+                V 
Sbjct: 403 DEESGDSDGSPKTSPKAVARR-------------FTTRRSSS----------------VD 433

Query: 413 EVSINRSLDSLDPAGLLTSPKFRSRNE--SYMRAMSTISQVSEMEVNGQFESVCESVFSE 470
           +  IN              P+   R+    Y R+++T  Q+S+ E+N Q E+VC SVF E
Sbjct: 434 QARIN----------CCVPPRIHPRSSIPGYSRSLTT-GQLSD-ELNQQLEAVCGSVFGE 481

Query: 471 LESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSST 530
           LESQAV+ALDLP  GCFRMRSHSY+RAI+ GCSQDD+C+ L +        T   +    
Sbjct: 482 LESQAVDALDLP--GCFRMRSHSYLRAIQAGCSQDDDCLPLLA--------TPAAVSGRP 531

Query: 531 VSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNST 590
            SS    ++K PPP+PP +   P ISITAQSST+SA +++   +G      S  GL    
Sbjct: 532 GSSF--NFRKAPPPIPPGSQAPPRISITAQSSTDSAHESFTAAEGPARRCSSADGLDGP- 588

Query: 591 ESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCL 650
               +M A T  +    A +   AS            T  I T+   +  +   ++ +  
Sbjct: 589 ----AMGARTLEL----APVPPRASPK--------PPTLIIKTIPGREELRSLARQRKWR 632

Query: 651 -SIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDN 709
            SIG+QV+   + D   EN++  +F S+GVQVEE+K   RF RSNSVT  VQADL+    
Sbjct: 633 PSIGVQVETISDSDT--ENRSRREFHSIGVQVEEDKRRARFKRSNSVTAGVQADLELEGL 690

Query: 710 LENSLESIEDNSCPGPMARQFSRDASTS-------------TVSIQGSGNHYHACAAD-D 755
              +  + ED +      R F R AS               TV  QG   +        +
Sbjct: 691 AGLATVATEDKALQ--FGRSFQRHASEPQPGPRAPTYSVFRTVHTQGQWAYREGYPLPYE 748

Query: 756 DFDTDFDPSILPPPDP---------WIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDR 806
              TD  P   P P P         WI+  +    ++ + S C RDG WF+K+L+AE ++
Sbjct: 749 PPATDGSPGPAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEK 808

Query: 807 MEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPT 866
           +E WCQQMERE  +  LPE+IL KIR+AVGS QLL++QK  QF  LC+++++P A P PT
Sbjct: 809 LEHWCQQMEREAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPT 868

Query: 867 SQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPKKPAKGPAP 926
            QDLAGFWD+LQLSIE++++KF EL QLKAN+WK ++P  K+E++ PPP+PKKP +G   
Sbjct: 869 FQDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKLLEP--KEEKKVPPPIPKKPLRGRGV 926

Query: 927 LIRERSLES--SQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977
            ++ERSL+S   QRQEARKRL+AAKRAAS R +SATESA+SIEIYIPEAQTRL
Sbjct: 927 PVKERSLDSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL 979


>gi|34335251 disks large-associated protein 4 isoform b [Homo
           sapiens]
          Length = 453

 Score =  425 bits (1092), Expect = e-118
 Identities = 231/453 (50%), Positives = 306/453 (67%), Gaps = 18/453 (3%)

Query: 532 SSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTE 591
           SSC+  YKKTPPPVPPRTT+KPFIS+T QSSTESAQD Y+D Q  + ++ SQSGLSNS++
Sbjct: 12  SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 71

Query: 592 SLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLS 651
           SLDS     +      A    PA +            +   T+T+ +   +   K +  S
Sbjct: 72  SLDSSTRPPSVTRGGVA----PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSS 127

Query: 652 IGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLE 711
           IGIQVD   +P    E    +KFQS+GVQVE++  +R    S+S+++    D D  D  +
Sbjct: 128 IGIQVD-CIQPVPKEEPSPATKFQSIGVQVEDD--WRSSVPSHSMSSRRDTDSDTQDAND 184

Query: 712 NSLESIE---DNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPP 768
           +S +S E    +  P P +         +    Q   N  +     D+ D   + S LPP
Sbjct: 185 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYG----DNSDPALEASSLPP 240

Query: 769 PDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDIL 828
           PDPW+++ +  P E  Q   C RDG+WFLKLLQAE +R+EGWC QM++E +ENNL E++L
Sbjct: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300

Query: 829 GKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKF 888
           GK+ +AVGSAQLLM+QKF QFR LCE+NLNP+A+PRPT+QDLAGFWD+LQLSIE+ISMKF
Sbjct: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360

Query: 889 DELHQLKANNWKQMDPLDKK--ERRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKR 944
           DEL+ LKAN+W+ ++  +K+  E++ PPPVPKKPAK    + R+++ ++S  QRQEARKR
Sbjct: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420

Query: 945 LMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977
           L+AAKRAASVRQNSATESA+SIEIY+PEAQTRL
Sbjct: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453


>gi|109891938 disks large-associated protein 4 isoform c [Homo
           sapiens]
          Length = 285

 Score =  309 bits (792), Expect = 7e-84
 Identities = 148/227 (65%), Positives = 189/227 (83%), Gaps = 4/227 (1%)

Query: 755 DDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQM 814
           D+ D   + S LPPPDPW+++ +  P E  Q   C RDG+WFLKLLQAE +R+EGWC QM
Sbjct: 59  DNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQM 118

Query: 815 EREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFW 874
           ++E +ENNL E++LGK+ +AVGSAQLLM+QKF QFR LCE+NLNP+A+PRPT+QDLAGFW
Sbjct: 119 DKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFW 178

Query: 875 DMLQLSIENISMKFDELHQLKANNWKQMDPLDKK--ERRAPPPVPKKPAKGPAPLIRERS 932
           D+LQLSIE+ISMKFDEL+ LKAN+W+ ++  +K+  E++ PPPVPKKPAK    + R+++
Sbjct: 179 DLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKA 238

Query: 933 LESS--QRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977
            ++S  QRQEARKRL+AAKRAASVRQNSATESA+SIEIY+PEAQTRL
Sbjct: 239 SDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 285


>gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
          Length = 842

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 55/179 (30%), Positives = 91/179 (50%), Gaps = 8/179 (4%)

Query: 790 HRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQF 849
           H    +F  +LQ+E +++   C + +R+  E ++P+D    IRTAVG  +LLM ++F QF
Sbjct: 427 HHGVPYFRNILQSETEKLTSHCFEWDRK-LELDIPDDAKDLIRTAVGQTRLLMKERFKQF 485

Query: 850 RELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKE 909
             L ++          T  DL GFWDM+   IE++  KF+ L +L+ + W+  + ++   
Sbjct: 486 EGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNM 545

Query: 910 RRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRA--ASVRQNSATESAESI 966
            +      KK   G A   ++   + + R  AR RL A K A    +RQ    E+A S+
Sbjct: 546 NK--NVFRKKVVSGIASKPKQ---DDAGRIAARNRLAAIKNAMRERIRQEECAETAVSV 599


>gi|226371667 discs large homolog 7 isoform a [Homo sapiens]
          Length = 846

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 55/179 (30%), Positives = 91/179 (50%), Gaps = 8/179 (4%)

Query: 790 HRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQF 849
           H    +F  +LQ+E +++   C + +R+  E ++P+D    IRTAVG  +LLM ++F QF
Sbjct: 427 HHGVPYFRNILQSETEKLTSHCFEWDRK-LELDIPDDAKDLIRTAVGQTRLLMKERFKQF 485

Query: 850 RELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKE 909
             L ++          T  DL GFWDM+   IE++  KF+ L +L+ + W+  + ++   
Sbjct: 486 EGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNM 545

Query: 910 RRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRA--ASVRQNSATESAESI 966
            +      KK   G A   ++   + + R  AR RL A K A    +RQ    E+A S+
Sbjct: 546 NK--NVFRKKVVSGIASKPKQ---DDAGRIAARNRLAAIKNAMRERIRQEECAETAVSV 599


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 79/313 (25%), Positives = 119/313 (38%), Gaps = 37/313 (11%)

Query: 158  PSKGSVNGGKASPDEAQAARYGKRSKSK-ERRAEPKARPSTS-PGWWSSDDNLDGDMCIY 215
            PS+ S++G  +SP      R   R +S+ +   EPKA P T  P   S       + C+ 
Sbjct: 1454 PSRHSLSG--SSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLT 1511

Query: 216  H------APSGV--MTMGRCP----DRSASQYFLEAYNTISEQAVKASRSNNDVKCSTCA 263
                   + S V   T+ R P     RS S   L+   + S Q    S S+ D K  T  
Sbjct: 1512 PQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKT-- 1569

Query: 264  NLPVSLDTPLLKKSAWSSTLTVSRAREVYQKASVNMDQAMVKSESCQQERSCQYLQVPQD 323
                   TPL ++S   S+  V     +  + S +     VK +     R+    Q   D
Sbjct: 1570 ------RTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP----RAAPRAQSGSD 1619

Query: 324  EWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDT--SPKPSPKVAARRESYLKATQ 381
              +   P+        RR RSGS  K  G    G S T  SP+  PK    R     + +
Sbjct: 1620 --SSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE 1677

Query: 382  PSLTELT-TLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDP----AGLLTSPKFRS 436
            P     T   + S+  SP+L  ++    R+ S  S   +     P    +  ++SP+   
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737

Query: 437  RNESYMRAMSTIS 449
            ++ S  R  S  S
Sbjct: 1738 KSRSSRRRRSASS 1750


>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 14/128 (10%)

Query: 510 SLRSSSPPRTTTTVRTIQSS-TVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQD 568
           S  SSS   +T+T   I SS T S+ IT+   T        TT   ISIT+ SS  S+  
Sbjct: 115 STSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSS-- 172

Query: 569 AYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTT 628
                      I S S  + ST S  +   +T+   + +       S    + T+T TT+
Sbjct: 173 -----------ITSTSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTS 221

Query: 629 TTIATVTT 636
           T+  + +T
Sbjct: 222 TSTTSTST 229


>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 14/128 (10%)

Query: 510 SLRSSSPPRTTTTVRTIQSS-TVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQD 568
           S  SSS   +T+T   I SS T S+ IT+   T        TT   ISIT+ SS  S+  
Sbjct: 115 STSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSS-- 172

Query: 569 AYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTT 628
                      I S S  + ST S  +   +T+   + +       S    + T+T TT+
Sbjct: 173 -----------ITSTSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTS 221

Query: 629 TTIATVTT 636
           T+  + +T
Sbjct: 222 TSTTSTST 229


>gi|55749544 SH3 multiple domains 1 [Homo sapiens]
          Length = 1105

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 26/231 (11%)

Query: 352 GDEDSGDSDT---SPKPSPKVAARRESYL---KATQPSLTELTTLKISNEHSPKLQIR-- 403
           GD DS  S +   + K SPK  + + S L   KA + +  E+     S   S  + I   
Sbjct: 612 GDSDSPGSSSLSLTRKNSPKSGSPKSSSLLKLKAEKNAQAEMGKNHSSASFSSSITINTT 671

Query: 404 ----SHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQ 459
               S S   ++S+ S +    S   AG+  +PK R++ ++   A  T    ++  V  +
Sbjct: 672 CCSSSSSSSSSLSKTSGDLKPRSASDAGIRGTPKVRAKKDADANAGLTSCPRAKPSVRPK 731

Query: 460 FESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRT 519
                    +  ESQ+ E +D+      ++R    +R   KG   +D      S  PP+T
Sbjct: 732 ------PFLNRAESQSQEKMDISTLRR-QLRPTGQLRGGLKGSKSED------SELPPQT 778

Query: 520 TTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTK-PFISITAQSSTESAQDA 569
            +   +  S   SS + T   T PP P +   + P  S    S+ +  QD+
Sbjct: 779 ASEAPSEGSRRSSSDLITLPATTPPCPTKKEWEGPATSYMTCSAYQKVQDS 829


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 38.9 bits (89), Expect = 0.024
 Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 3/61 (4%)

Query: 515 SPPRTTTTVRTIQSSTVSSCITTYKKTPPPV---PPRTTTKPFISITAQSSTESAQDAYM 571
           SPP   TT+  +Q S V S   +   +PPP    PP  T KP + + A S++E+A++   
Sbjct: 706 SPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ 765

Query: 572 D 572
           D
Sbjct: 766 D 766


>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
          Length = 2087

 Score = 38.1 bits (87), Expect = 0.041
 Identities = 79/348 (22%), Positives = 126/348 (36%), Gaps = 61/348 (17%)

Query: 356  SGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVS 415
            S   D S KPS        ++       L++  ++ IS   S  L  R    +  VS  +
Sbjct: 871  SPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTT 930

Query: 416  INRSLDSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQA 475
               +  S       T  K     ++  R+ + I ++   E   Q     ES    L+  A
Sbjct: 931  AQNASSS-------TWDKCVEERDATNRSPTQIVKMKTNETVAQ--EAYESEVQPLDQVA 981

Query: 476  VEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCI 535
             E ++LP      + S S  +A+  G +Q        +  PP+ +  V ++         
Sbjct: 982  AEEVELPGKEDQSVSS-SQSKAVASGQTQTGAV----THDPPQDSVPVSSVSL------- 1029

Query: 536  TTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSN------- 588
                  PPP PP+   +    + A +  ESAQ A      + G   SQ+G +N       
Sbjct: 1030 -----IPPPPPPKNVAR----MLALALAESAQQASTQSLKRPG--TSQAGYTNYGDIAVA 1078

Query: 589  STESLDSMKALTAAIEAANAQIHGPASQ-HMGNNT---------ATVTTTTTIATVTTED 638
            +TE   S      A++ A  Q   PA Q H+ NN           T  T     + TTE 
Sbjct: 1079 TTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTES 1138

Query: 639  RKKDHFKKNRCLSIGIQVD-DAEEPDKTGENKAPSKFQSVGVQVEEEK 685
             ++ H           QVD    +P +   +  P K +   V ++ EK
Sbjct: 1139 GEQHH-----------QVDLTGNQPHQAYLSGDPEKARITSVPLDSEK 1175


>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
          Length = 1738

 Score = 38.1 bits (87), Expect = 0.041
 Identities = 79/348 (22%), Positives = 126/348 (36%), Gaps = 61/348 (17%)

Query: 356 SGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVS 415
           S   D S KPS        ++       L++  ++ IS   S  L  R    +  VS  +
Sbjct: 522 SPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTT 581

Query: 416 INRSLDSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQA 475
              +  S       T  K     ++  R+ + I ++   E   Q     ES    L+  A
Sbjct: 582 AQNASSS-------TWDKCVEERDATNRSPTQIVKMKTNETVAQ--EAYESEVQPLDQVA 632

Query: 476 VEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCI 535
            E ++LP      + S S  +A+  G +Q        +  PP+ +  V ++         
Sbjct: 633 AEEVELPGKEDQSVSS-SQSKAVASGQTQTGAV----THDPPQDSVPVSSVSL------- 680

Query: 536 TTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSN------- 588
                 PPP PP+   +    + A +  ESAQ A      + G   SQ+G +N       
Sbjct: 681 -----IPPPPPPKNVAR----MLALALAESAQQASTQSLKRPG--TSQAGYTNYGDIAVA 729

Query: 589 STESLDSMKALTAAIEAANAQIHGPASQ-HMGNNT---------ATVTTTTTIATVTTED 638
           +TE   S      A++ A  Q   PA Q H+ NN           T  T     + TTE 
Sbjct: 730 TTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTES 789

Query: 639 RKKDHFKKNRCLSIGIQVD-DAEEPDKTGENKAPSKFQSVGVQVEEEK 685
            ++ H           QVD    +P +   +  P K +   V ++ EK
Sbjct: 790 GEQHH-----------QVDLTGNQPHQAYLSGDPEKARITSVPLDSEK 826


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 37.4 bits (85), Expect = 0.069
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 40  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 91

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   ++   TA  E     I G  +     MG+ T T +T
Sbjct: 92  -AGSENTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNST 150

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 151 TSSETTVTS 159



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 477 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 536

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 537 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 589

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 590 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 648

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 649 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 708

Query: 742 QGSG 745
           +GSG
Sbjct: 709 EGSG 712



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 938  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 994

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 995  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1050



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 836 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 888

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 889 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 948

Query: 633 TVTTE 637
           T  +E
Sbjct: 949 TEGSE 953



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513  SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
            +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 887  ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 938

Query: 573  GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
              G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 939  TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 994

Query: 629  TTIATVTTE 637
            TT +T  +E
Sbjct: 995  TTASTAGSE 1003



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 657 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 716

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 717 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 772

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 773 TTSASTTGSE 782



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 319 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 378

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 379 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 438

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 439 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 497

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 498 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 553

Query: 746 N 746
           N
Sbjct: 554 N 554


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 76/397 (19%), Positives = 146/397 (36%), Gaps = 54/397 (13%)

Query: 358  DSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSIN 417
            +S ++  P+P+  +  +    AT+PS      L  +       Q+ S S   +  + +++
Sbjct: 8995 ESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMS 9054

Query: 418  RSLDSLDPAGLLTSPKFRSRNESYMRAM-----STISQVSEMEVNGQFESVCESVFSE-L 471
            + + +     L TSP      E  +        +T      ++ +  F S   S  S+  
Sbjct: 9055 QDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGF 9114

Query: 472  ESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVS-LRSSSPPRTTTTVRTIQSST 530
                + AL    PG     SH    ++E+  S      S + +SS P ++T   +I SS+
Sbjct: 9115 SHSQMTALMSRTPGDVPWLSHP---SVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSS 9171

Query: 531  V-------SSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQ 583
            +       S  + T +       P T++ P +S T+                   +I++ 
Sbjct: 9172 LPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTS------------------AEILAI 9213

Query: 584  SGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDH 643
            + ++  TE L+    +T      +   H   S  + ++  T  T++   T  T D     
Sbjct: 9214 TEVTTDTEKLEMTNVVT------SGYTHESPSSVLADSVTTKATSSMGITYPTGD----- 9262

Query: 644  FKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQAD 703
               N   S     D +    K+  +  P   ++  +  E      + T  +SV T    +
Sbjct: 9263 --TNVLTSTPAFSDTSRIQTKSKLSLTPGLMET-SISEETSSATEKSTVLSSVPTGATTE 9319

Query: 704  LDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVS 740
            +   + + +S  SI     PGP     S D S  T++
Sbjct: 9320 VSRTEAISSSRTSI-----PGPAQSTMSSDTSMETIT 9351



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 7/135 (5%)

Query: 507  ECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESA 566
            E  S  S+SPP T +T +TI + T  S +T+  +         T+    S   Q   +S 
Sbjct: 6136 EASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSE 6195

Query: 567  QDAYMDGQGQRGDIISQSGLS-NSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATV 625
              + M+      D++  S  S     SL S   L   +  + + +     +H  ++  +V
Sbjct: 6196 TTSVMN--NDLNDVLKTSPFSAEEANSLSSQAPL--LVTTSPSPVTSTLQEHSTSSLVSV 6251

Query: 626  TT--TTTIATVTTED 638
            T+  T T+A +T  D
Sbjct: 6252 TSVPTPTLAKITDMD 6266



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 39/164 (23%), Positives = 65/164 (39%), Gaps = 9/164 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            TTT    +  ST+ S   T ++T     P T +    S +   +  ++        G   
Sbjct: 3552 TTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTIS 3611

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA-TVTTE 637
             + + S L++STE LDSM      I      +  P+S      T T T+  T++ + TT 
Sbjct: 3612 TMHTTSFLASSTE-LDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTA 3670

Query: 638  DRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQV 681
                  F + + +SI +       PD    +  PS  ++  V V
Sbjct: 3671 STPISTFSRVQRMSISV-------PDILSTSWTPSSTEAEDVPV 3707


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 696 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 751

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 752 TTSASTTGSE 761



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 696 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 751

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 752 TTSASTTGSE 761



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 696 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 751

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 752 TTSASTTGSE 761



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
           sapiens]
          Length = 1521

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 696 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 751

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 752 TTSASTTGSE 761



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 696 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 751

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 752 TTSASTTGSE 761



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 696 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 751

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 752 TTSASTTGSE 761



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 696 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 751

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 752 TTSASTTGSE 761



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           S++   TTT +     +T +S   +   TP P   +TT    +SI+    T ++      
Sbjct: 19  STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT---IVSISGSEITTTST----- 70

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKAL--TAAIEAANAQIHGPAS---QHMGNNTATVTT 627
             G     +S +G   +T S+   +    TA  E     I G  +     MG+ T T +T
Sbjct: 71  -AGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 628 TTTIATVTT 636
           T++  TVT+
Sbjct: 130 TSSETTVTS 138



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 52/244 (21%), Positives = 82/244 (33%), Gaps = 19/244 (7%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFI--SITAQSSTESAQDAY 570
           +S+    TTTV T  S T ++  T  + T        TT  F   S T  +STE ++   
Sbjct: 456 ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 571 MDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTT 630
           +   G     +S  G  N+T S       T   E       G  +       + +TT +T
Sbjct: 516 VSATGSEMTTVSTEGSENTTVS-------TTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 631 IATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRF 690
               TT D   +        + G +       D      + +  ++        +     
Sbjct: 569 TGAETTTD-STEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 691 TRSNSVTTA--------VQADLDFHDNLENSLESIED-NSCPGPMARQFSRDASTSTVSI 741
           T S+  TTA          +  D    + ++  S     S  G      S   S +TVS 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 742 QGSG 745
           +GSG
Sbjct: 688 EGSG 691



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)

Query: 519  TTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRG 578
            +TT   T  +ST  S  TT       +   +TT    S T   S E ++   +   G   
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTG---SETITVSAEGSETTTVTTMGSET 973

Query: 579  DIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTED 638
               S +G   +T S    +  TA+IE +            G+ T TV+TT T  T+T+ +
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETT----TVSSTGSETTTVSTTGTETTITSTE 1029



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTTV T  S T+ +     + T       TTT    S T  +STE ++     
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETT-------TTTSTEGSETTTASTEGSETTTAS 867

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
            +       +  G   +T S +  +  T + E +           +   + T + TTT +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 633 TVTTE 637
           T  +E
Sbjct: 928 TEGSE 932



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 16/129 (12%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
           +S+    TTT  TI S T ++  T   +T       TTT    S T  +STE ++   + 
Sbjct: 866 ASTESSETTTATTIGSETTTAS-TEGSET-------TTTSTEGSETTTASTEGSEITTVS 917

Query: 573 GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT----T 628
             G      S  G   +T S +  + LT      +  I   A    G+ T TVTT    T
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSE-LTTVSTTGSETITVSAE---GSETTTVTTMGSET 973

Query: 629 TTIATVTTE 637
           TT +T  +E
Sbjct: 974 TTASTAGSE 982



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 513 SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP-PRTTTKPFISITAQSSTESAQDAYM 571
           +S+    TTTV T  S T     T  ++T        TTT          STE +    +
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 572 DGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTT---- 627
              G     +S +G   +T S +  +  TA+I  +        +   G+ T T +T    
Sbjct: 696 SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETT----TASTEGSETTTASTEGSE 751

Query: 628 TTTIATVTTE 637
           TT+ +T  +E
Sbjct: 752 TTSASTTGSE 761



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 45/241 (18%), Positives = 83/241 (34%), Gaps = 9/241 (3%)

Query: 510 SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
           ++ S +   +T    T + ST SS +TT           +T     +  + + +E+   +
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 570 YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTT 629
            M  +            + STE  ++  A T   EA      G  +  +    +  TTT 
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTC 417

Query: 630 TIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRR 689
           T  +  T       F+     + G ++  A   D      +    ++  V     +    
Sbjct: 418 TEGSEMTA-VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTA 476

Query: 690 FTRSNSVTTAVQADLD----FHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSG 745
           +T  +  TTA    L+    F    + +  S E +      A      +  +TVS +GS 
Sbjct: 477 YTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA----TGSEMTTVSTEGSE 532

Query: 746 N 746
           N
Sbjct: 533 N 533


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 36.6 bits (83), Expect = 0.12
 Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 16/124 (12%)

Query: 513  SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
            +SS   T  T++ + S+  +  + + + TP   P   T  P +  TA + T ++  A   
Sbjct: 3766 ASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTA--- 3822

Query: 573  GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
                    I  S L  +   L      TA +  A      P+S     +T+TV TTTT  
Sbjct: 3823 --------IPSSSLGTAWTRLSQTTTPTATMSTAT-----PSSTPETVHTSTVLTTTTTT 3869

Query: 633  TVTT 636
            T  T
Sbjct: 3870 TRAT 3873



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 34/140 (24%), Positives = 53/140 (37%), Gaps = 19/140 (13%)

Query: 510  SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
            +LR++ PP+  TT  T  +      +T+ K TP   P   T  P +  TA + T ++   
Sbjct: 2622 TLRTAPPPKVLTTTATTPT------VTSSKATPSSSPGTATALPALRSTATTPTATSVTP 2675

Query: 570  YMDGQ-GQRGDIISQSGLSNSTESL------------DSMKALTAAIEAANAQIHGPASQ 616
                  G     +SQ+    +T S              ++   TA    A   +  P+S 
Sbjct: 2676 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSST 2735

Query: 617  HMGNNTATVTTTTTIATVTT 636
                +T  V TTTT     T
Sbjct: 2736 PGTAHTTKVPTTTTTGFTAT 2755



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 9/71 (12%)

Query: 485  GCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPP 544
            G F+M  +  +R +   C  DD C    ++ PP  TT + T  ++T  +  +T + T  P
Sbjct: 2276 GVFKMCYNYRIRVL---CCSDDHCRGRATTPPP--TTELETATTTTTQALFSTPQPTSSP 2330

Query: 545  ----VPPRTTT 551
                 PP +TT
Sbjct: 2331 GLTRAPPASTT 2341



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 36/149 (24%), Positives = 55/149 (36%), Gaps = 26/149 (17%)

Query: 510  SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
            +LRS++   T T+V  I SS++ +  T   +T  P    +T  P  S    + T +   A
Sbjct: 2660 ALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPS-STPETAHTSTVLTA 2718

Query: 570  YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHG----------------- 612
                 G  G + + S    +  +       T    A  +   G                 
Sbjct: 2719 TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTT 2778

Query: 613  ------PASQHMGNNTATV--TTTTTIAT 633
                  P+S     +TATV  TTTTT+AT
Sbjct: 2779 RGSTVTPSSIPGTTHTATVLTTTTTTVAT 2807



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 13/140 (9%)

Query: 510  SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
            S  ++S  + T     + ++  +  +T+ K TP   P   T  P +  TA + T ++  A
Sbjct: 4938 STATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTA 4997

Query: 570  YMDGQ-GQRGDIISQSGLSNSTESL------------DSMKALTAAIEAANAQIHGPASQ 616
                  G     +SQ+    +T S              ++   TA    A   +  P+S 
Sbjct: 4998 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSST 5057

Query: 617  HMGNNTATVTTTTTIATVTT 636
                +T  V TTTT     T
Sbjct: 5058 PGTAHTTKVPTTTTTGFTAT 5077



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 13/140 (9%)

Query: 510  SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
            S  ++S  + T     + ++  +  +T+ K TP   P   T  P +  TA + T ++  A
Sbjct: 3118 STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTA 3177

Query: 570  YMDGQ-GQRGDIISQSGLSNSTESL------------DSMKALTAAIEAANAQIHGPASQ 616
                  G     +SQ+    +T S              ++   TA    A   +  P+S 
Sbjct: 3178 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSST 3237

Query: 617  HMGNNTATVTTTTTIATVTT 636
                +T  V TTTT     T
Sbjct: 3238 PGTAHTTKVLTTTTTGFTAT 3257



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 18/140 (12%)

Query: 514  SSPPRTT---TTVRTIQSSTVSSCITTYKKTPPPV--PPRTTTKPFISITAQSSTESAQD 568
            SS P TT   T + T  ++T S+  T    + P    PP+  T P  + TA SS  ++  
Sbjct: 4714 SSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSS 4773

Query: 569  A--------YMDGQGQRGDIISQSGLSNST-ESLDSMKALTAAIEAANAQIHGPASQHMG 619
            +         +     +    S + + +ST  +  ++   T    A  + IH P+S    
Sbjct: 4774 SPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIH-PSSTPET 4832

Query: 620  NNTATVTT---TTTIATVTT 636
             +T+TV T   TTT AT +T
Sbjct: 4833 THTSTVLTTKATTTRATSST 4852


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 36.6 bits (83), Expect = 0.12
 Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 16/124 (12%)

Query: 513  SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
            +SS   T  T++ + S+  +  + + + TP   P   T  P +  TA + T ++  A   
Sbjct: 3186 ASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTA--- 3242

Query: 573  GQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIA 632
                    I  S L  +   L      TA +  A      P+S     +T+TV TTTT  
Sbjct: 3243 --------IPSSSLGTAWTRLSQTTTPTATMSTAT-----PSSTPETVHTSTVLTTTTTT 3289

Query: 633  TVTT 636
            T  T
Sbjct: 3290 TRAT 3293



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 34/140 (24%), Positives = 53/140 (37%), Gaps = 19/140 (13%)

Query: 510  SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
            +LR++ PP+  TT  T  +      +T+ K TP   P   T  P +  TA + T ++   
Sbjct: 1932 TLRTAPPPKVLTTTATTPT------VTSSKATPSSSPGTATALPALRSTATTPTATSVTP 1985

Query: 570  YMDGQ-GQRGDIISQSGLSNSTESL------------DSMKALTAAIEAANAQIHGPASQ 616
                  G     +SQ+    +T S              ++   TA    A   +  P+S 
Sbjct: 1986 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSST 2045

Query: 617  HMGNNTATVTTTTTIATVTT 636
                +T  V TTTT     T
Sbjct: 2046 PGTAHTTKVPTTTTTGFTAT 2065



 Score = 33.5 bits (75), Expect = 1.00
 Identities = 29/130 (22%), Positives = 48/130 (36%), Gaps = 12/130 (9%)

Query: 514  SSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP--------PRTTTKPFISITAQSS--- 562
            SS P T  T   + ++T ++  T    TP   P        P TTT  F +  + S    
Sbjct: 3271 SSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA 3330

Query: 563  -TESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNN 621
             T     +       RG  ++ S +  +T +   +   T  +   +      ++Q  G  
Sbjct: 3331 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTP 3390

Query: 622  TATVTTTTTI 631
             +  TT TTI
Sbjct: 3391 PSLTTTATTI 3400



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 9/71 (12%)

Query: 485  GCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPP 544
            G F+M  +  +R +   C  DD C    ++ PP  TT + T  ++T  +  +T + T  P
Sbjct: 1586 GVFKMCYNYRIRVL---CCSDDHCRGRATTPPP--TTELETATTTTTQALFSTPQPTSSP 1640

Query: 545  ----VPPRTTT 551
                 PP +TT
Sbjct: 1641 GLTRAPPASTT 1651



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 36/149 (24%), Positives = 55/149 (36%), Gaps = 26/149 (17%)

Query: 510  SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
            +LRS++   T T+V  I SS++ +  T   +T  P    +T  P  S    + T +   A
Sbjct: 1970 ALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPS-STPETAHTSTVLTA 2028

Query: 570  YMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHG----------------- 612
                 G  G + + S    +  +       T    A  +   G                 
Sbjct: 2029 TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTT 2088

Query: 613  ------PASQHMGNNTATV--TTTTTIAT 633
                  P+S     +TATV  TTTTT+AT
Sbjct: 2089 RGSTVTPSSIPGTTHTATVLTTTTTTVAT 2117



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 13/140 (9%)

Query: 510  SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
            S  ++S  + T     + ++  +  +T+ K TP   P   T  P +  TA + T ++  A
Sbjct: 4468 STATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTA 4527

Query: 570  YMDGQ-GQRGDIISQSGLSNSTESL------------DSMKALTAAIEAANAQIHGPASQ 616
                  G     +SQ+    +T S              ++   TA    A   +  P+S 
Sbjct: 4528 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSST 4587

Query: 617  HMGNNTATVTTTTTIATVTT 636
                +T  V TTTT     T
Sbjct: 4588 PGTAHTTKVPTTTTTGFTAT 4607



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 29/129 (22%), Positives = 51/129 (39%), Gaps = 7/129 (5%)

Query: 513  SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMD 572
            SSS PRT TT+  + S+   S  T++   P      T T P  + T  S+  +   +   
Sbjct: 4728 SSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTP 4787

Query: 573  GQGQRGDIISQSG----LSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTT 628
                   +++ +      +NST +  S    T  +          A+     +TAT+++T
Sbjct: 4788 ETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAAT---GSTATLSST 4844

Query: 629  TTIATVTTE 637
                 + TE
Sbjct: 4845 PGTTWILTE 4853



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 29/131 (22%), Positives = 51/131 (38%), Gaps = 14/131 (10%)

Query: 514  SSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVP--------PRTTTKPFISITAQSSTES 565
            SS P T  T   + ++  ++  T    TP   P        P TTT  F ++T  SS  +
Sbjct: 3828 SSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGF-TVTPSSSPGT 3886

Query: 566  AQD-----AYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGN 620
            A+      +        G  ++ S +  +T +   +   T  +   +      ++Q  G 
Sbjct: 3887 ARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGT 3946

Query: 621  NTATVTTTTTI 631
              + +TT TTI
Sbjct: 3947 PPSLITTATTI 3957



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 28/130 (21%), Positives = 56/130 (43%), Gaps = 7/130 (5%)

Query: 513  SSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQD---- 568
            S +PP  TTT  TI ++  ++  ++   T P  P  T+T    + T+  +T S+      
Sbjct: 4677 SGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTAT 4736

Query: 569  --AYMDGQGQRGDIISQSGLSNST-ESLDSMKALTAAIEAANAQIHGPASQHMGNNTATV 625
                +     +    S + + +ST  +  ++ A T    +  + IH  ++    + +  +
Sbjct: 4737 TLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVL 4796

Query: 626  TTTTTIATVT 635
            TTT T+   T
Sbjct: 4797 TTTATMTRAT 4806



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 13/140 (9%)

Query: 510  SLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDA 569
            S  ++S  + T     + ++  +  +T+ K TP   P   T  P +  TA + T ++  A
Sbjct: 2483 STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTA 2542

Query: 570  YMDGQ-GQRGDIISQSGLSNSTESL------------DSMKALTAAIEAANAQIHGPASQ 616
                  G     +SQ+    +T S              ++   TA    A   +  P+S 
Sbjct: 2543 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSST 2602

Query: 617  HMGNNTATVTTTTTIATVTT 636
                +T  V TTTT     T
Sbjct: 2603 PGTAHTTKVLTTTTTGFTAT 2622



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 18/140 (12%)

Query: 514  SSPPRTT---TTVRTIQSSTVSSCITTYKKTPPPV--PPRTTTKPFISITAQSSTESAQD 568
            SS P TT   T + T  ++T S+  T    + P    PP+  T P  + TA SS  ++  
Sbjct: 4244 SSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSS 4303

Query: 569  A--------YMDGQGQRGDIISQSGLSNST-ESLDSMKALTAAIEAANAQIHGPASQHMG 619
            +         +     +    S + + +ST  +  ++   T    A  + IH P+S    
Sbjct: 4304 SPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIH-PSSTPET 4362

Query: 620  NNTATVTT---TTTIATVTT 636
             +T+TV T   TTT AT +T
Sbjct: 4363 THTSTVLTTKATTTRATSST 4382


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 36.6 bits (83), Expect = 0.12
 Identities = 51/254 (20%), Positives = 101/254 (39%), Gaps = 35/254 (13%)

Query: 333  KDDEIPCRRM--RSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQ----PSLTE 386
            +++EIP   +   +   ++++  E+S + + + +   +  A  ++    TQ    P ++ 
Sbjct: 1411 EEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSM 1470

Query: 387  LTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMS 446
            +     S  +SP   ++SH   ++V  VS + ++ +L+      SP+  S +   M+ M 
Sbjct: 1471 VEDCHASEHNSPISSVQSHPS-QSVRSVS-SPNVPALESGYTQISPEQGSLSAPSMQNME 1528

Query: 447  TISQVSEMEVNGQFESVCESVFSELES--------QAVEALDLPMPGCFRMRSHSYVRAI 498
            T   +    V+   + V +S FS+L S        +   + D  M G     S S     
Sbjct: 1529 TSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCS 1588

Query: 499  EKGCSQDDE------------------CVSLRSSS-PPRTTTTVRTIQSSTVSSCITTYK 539
              G S                      C  ++ SS  P    ++++ QS  V    +  +
Sbjct: 1589 YGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQ 1648

Query: 540  KTPPPVPPRTTTKP 553
            + PPP PP+    P
Sbjct: 1649 QQPPPPPPQQPQPP 1662


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.126    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,447,434
Number of Sequences: 37866
Number of extensions: 1878498
Number of successful extensions: 8188
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 7333
Number of HSP's gapped (non-prelim): 640
length of query: 977
length of database: 18,247,518
effective HSP length: 112
effective length of query: 865
effective length of database: 14,006,526
effective search space: 12115644990
effective search space used: 12115644990
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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