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Search of human proteins with 19718746
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
sapiens]
(437 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa... 914 0.0
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 914 0.0
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [... 671 0.0
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H... 671 0.0
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [... 291 6e-79
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [... 291 6e-79
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [... 291 6e-79
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [... 291 6e-79
gi|4505531 oxysterol binding protein [Homo sapiens] 290 2e-78
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [... 289 3e-78
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [... 289 3e-78
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 283 2e-76
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] 279 3e-75
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 142 5e-34
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 142 5e-34
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [... 139 7e-33
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ... 139 7e-33
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [... 139 7e-33
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap... 124 2e-28
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap... 124 2e-28
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap... 124 2e-28
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap... 124 2e-28
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap... 124 2e-28
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap... 124 2e-28
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap... 124 2e-28
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] 110 2e-24
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 107 2e-23
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 37 0.046
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 37 0.046
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 37 0.046
>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
sapiens]
Length = 437
Score = 914 bits (2363), Expect = 0.0
Identities = 437/437 (100%), Positives = 437/437 (100%)
Query: 1 MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEP 60
MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEP
Sbjct: 1 MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEP 60
Query: 61 LSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETY 120
LSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETY
Sbjct: 61 LSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETY 120
Query: 121 ELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTIT 180
ELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTIT
Sbjct: 121 ELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTIT 180
Query: 181 LELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKEL 240
LELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKEL
Sbjct: 181 LELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKEL 240
Query: 241 HKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEEL 300
HKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEEL
Sbjct: 241 HKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEEL 300
Query: 301 DEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCR 360
DEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCR
Sbjct: 301 DEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCR 360
Query: 361 LRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWI 420
LRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWI
Sbjct: 361 LRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWI 420
Query: 421 YSGSYWDRNYFNLPDIY 437
YSGSYWDRNYFNLPDIY
Sbjct: 421 YSGSYWDRNYFNLPDIY 437
>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
sapiens]
Length = 950
Score = 914 bits (2363), Expect = 0.0
Identities = 437/437 (100%), Positives = 437/437 (100%)
Query: 1 MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEP 60
MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEP
Sbjct: 514 MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEP 573
Query: 61 LSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETY 120
LSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETY
Sbjct: 574 LSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETY 633
Query: 121 ELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTIT 180
ELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTIT
Sbjct: 634 ELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTIT 693
Query: 181 LELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKEL 240
LELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKEL
Sbjct: 694 LELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKEL 753
Query: 241 HKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEEL 300
HKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEEL
Sbjct: 754 HKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEEL 813
Query: 301 DEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCR 360
DEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCR
Sbjct: 814 DEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCR 873
Query: 361 LRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWI 420
LRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWI
Sbjct: 874 LRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWI 933
Query: 421 YSGSYWDRNYFNLPDIY 437
YSGSYWDRNYFNLPDIY
Sbjct: 934 YSGSYWDRNYFNLPDIY 950
>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
[Homo sapiens]
Length = 480
Score = 671 bits (1731), Expect = 0.0
Identities = 305/427 (71%), Positives = 367/427 (85%), Gaps = 5/427 (1%)
Query: 15 NGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHT 74
NGI+KHRTSLP+PMFSR+DFS+W+IL+KC+G+ELSKITMP+ FNEPLSFLQR+TEYMEH
Sbjct: 55 NGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHV 114
Query: 75 YLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISE 134
YLIH+AS P+ERMQ VAAFAVSAVASQWERTGKPFNPLLGETYEL+R+DLGFR ISE
Sbjct: 115 YLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISE 174
Query: 135 QVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTN 194
QVSHHPPISAFH+EGLN+DF+FHGSIYPKLKFWGKSVEAEP+GTITLELL+HNEAYTWTN
Sbjct: 175 QVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTN 234
Query: 195 PTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKK 254
PTCCVHN+I+GKLWIEQYG VEI+NH+TG KCVL+FKPCGLFGKELHKVEG+IQDK+KKK
Sbjct: 235 PTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKK 294
Query: 255 LCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKK----NSKQMSTSEELDEMPVPDSES 310
L +YGKWTECL+ +DP +++++KK +++ +K + S+ D++PV E+
Sbjct: 295 LFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVA-QET 353
Query: 311 VFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMEN 370
V +IPGS LLWRI RPPNSAQMYNFTSF + LNE++ ME +P TDCRLRPDIR MEN
Sbjct: 354 VQVIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMEN 413
Query: 371 GEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWDRNY 430
G +D AS+EK+RLEEKQR AR+ R+K E +W+TRWF+ G NPY G DW+Y+G Y++RN+
Sbjct: 414 GNMDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNF 473
Query: 431 FNLPDIY 437
+ PDIY
Sbjct: 474 SDCPDIY 480
>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
sapiens]
Length = 468
Score = 671 bits (1731), Expect = 0.0
Identities = 305/427 (71%), Positives = 367/427 (85%), Gaps = 5/427 (1%)
Query: 15 NGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHT 74
NGI+KHRTSLP+PMFSR+DFS+W+IL+KC+G+ELSKITMP+ FNEPLSFLQR+TEYMEH
Sbjct: 43 NGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHV 102
Query: 75 YLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISE 134
YLIH+AS P+ERMQ VAAFAVSAVASQWERTGKPFNPLLGETYEL+R+DLGFR ISE
Sbjct: 103 YLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISE 162
Query: 135 QVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTN 194
QVSHHPPISAFH+EGLN+DF+FHGSIYPKLKFWGKSVEAEP+GTITLELL+HNEAYTWTN
Sbjct: 163 QVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTN 222
Query: 195 PTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKK 254
PTCCVHN+I+GKLWIEQYG VEI+NH+TG KCVL+FKPCGLFGKELHKVEG+IQDK+KKK
Sbjct: 223 PTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKK 282
Query: 255 LCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKK----NSKQMSTSEELDEMPVPDSES 310
L +YGKWTECL+ +DP +++++KK +++ +K + S+ D++PV E+
Sbjct: 283 LFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVA-QET 341
Query: 311 VFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMEN 370
V +IPGS LLWRI RPPNSAQMYNFTSF + LNE++ ME +P TDCRLRPDIR MEN
Sbjct: 342 VQVIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMEN 401
Query: 371 GEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWDRNY 430
G +D AS+EK+RLEEKQR AR+ R+K E +W+TRWF+ G NPY G DW+Y+G Y++RN+
Sbjct: 402 GNMDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNF 461
Query: 431 FNLPDIY 437
+ PDIY
Sbjct: 462 SDCPDIY 468
>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
[Homo sapiens]
Length = 820
Score = 291 bits (746), Expect = 6e-79
Identities = 160/409 (39%), Positives = 229/409 (55%), Gaps = 52/409 (12%)
Query: 19 KHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIH 78
+ RT LP+P S ++ S+W+ILR IG +LSK+ MPV NEPL+ LQRL E +E++ L+
Sbjct: 444 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 503
Query: 79 KASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVS 137
KA+ + P+ERM VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+ SEQVS
Sbjct: 504 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 563
Query: 138 HHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTC 197
HHPPISA HAE N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 564 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 621
Query: 198 CVHNIIVGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLC 256
C+HNI+ G+ WIE YG + I N H C +NF + H++EG + D+S K +
Sbjct: 622 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 681
Query: 257 ALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPG 316
L+GKW E +Y ++
Sbjct: 682 RLFGKWHESIYCGGGSS------------------------------------------- 698
Query: 317 SVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQA 376
S +WR P P Q Y+FT FA+ LNE+D +S++P TD R RPD R +E G +++A
Sbjct: 699 SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEA 758
Query: 377 SEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425
+K+R+E+ QR R+ ++ + + R+F + + W+ +G+Y
Sbjct: 759 EIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 802
>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
[Homo sapiens]
Length = 851
Score = 291 bits (746), Expect = 6e-79
Identities = 160/409 (39%), Positives = 229/409 (55%), Gaps = 52/409 (12%)
Query: 19 KHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIH 78
+ RT LP+P S ++ S+W+ILR IG +LSK+ MPV NEPL+ LQRL E +E++ L+
Sbjct: 475 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 534
Query: 79 KASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVS 137
KA+ + P+ERM VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+ SEQVS
Sbjct: 535 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 594
Query: 138 HHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTC 197
HHPPISA HAE N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 595 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 652
Query: 198 CVHNIIVGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLC 256
C+HNI+ G+ WIE YG + I N H C +NF + H++EG + D+S K +
Sbjct: 653 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 712
Query: 257 ALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPG 316
L+GKW E +Y ++
Sbjct: 713 RLFGKWHESIYCGGGSS------------------------------------------- 729
Query: 317 SVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQA 376
S +WR P P Q Y+FT FA+ LNE+D +S++P TD R RPD R +E G +++A
Sbjct: 730 SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEA 789
Query: 377 SEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425
+K+R+E+ QR R+ ++ + + R+F + + W+ +G+Y
Sbjct: 790 EIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 833
>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
[Homo sapiens]
Length = 856
Score = 291 bits (746), Expect = 6e-79
Identities = 160/409 (39%), Positives = 229/409 (55%), Gaps = 52/409 (12%)
Query: 19 KHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIH 78
+ RT LP+P S ++ S+W+ILR IG +LSK+ MPV NEPL+ LQRL E +E++ L+
Sbjct: 480 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 539
Query: 79 KASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVS 137
KA+ + P+ERM VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+ SEQVS
Sbjct: 540 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 599
Query: 138 HHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTC 197
HHPPISA HAE N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 600 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 657
Query: 198 CVHNIIVGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLC 256
C+HNI+ G+ WIE YG + I N H C +NF + H++EG + D+S K +
Sbjct: 658 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 717
Query: 257 ALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPG 316
L+GKW E +Y ++
Sbjct: 718 RLFGKWHESIYCGGGSS------------------------------------------- 734
Query: 317 SVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQA 376
S +WR P P Q Y+FT FA+ LNE+D +S++P TD R RPD R +E G +++A
Sbjct: 735 SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEA 794
Query: 377 SEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425
+K+R+E+ QR R+ ++ + + R+F + + W+ +G+Y
Sbjct: 795 EIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 838
>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
[Homo sapiens]
Length = 887
Score = 291 bits (746), Expect = 6e-79
Identities = 160/409 (39%), Positives = 229/409 (55%), Gaps = 52/409 (12%)
Query: 19 KHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIH 78
+ RT LP+P S ++ S+W+ILR IG +LSK+ MPV NEPL+ LQRL E +E++ L+
Sbjct: 511 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 570
Query: 79 KASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVS 137
KA+ + P+ERM VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+ SEQVS
Sbjct: 571 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 630
Query: 138 HHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTC 197
HHPPISA HAE N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 631 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 688
Query: 198 CVHNIIVGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLC 256
C+HNI+ G+ WIE YG + I N H C +NF + H++EG + D+S K +
Sbjct: 689 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 748
Query: 257 ALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPG 316
L+GKW E +Y ++
Sbjct: 749 RLFGKWHESIYCGGGSS------------------------------------------- 765
Query: 317 SVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQA 376
S +WR P P Q Y+FT FA+ LNE+D +S++P TD R RPD R +E G +++A
Sbjct: 766 SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEA 825
Query: 377 SEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425
+K+R+E+ QR R+ ++ + + R+F + + W+ +G+Y
Sbjct: 826 EIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 869
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 290 bits (742), Expect = 2e-78
Identities = 183/439 (41%), Positives = 241/439 (54%), Gaps = 53/439 (12%)
Query: 18 KKHRTSLP-SPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYL 76
K+ RT +P P +S N +WSI++ CIG ELSKI MPV FNEPLS LQRLTE +E+ L
Sbjct: 403 KEKRTRIPYKPNYSLN---LWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHEL 459
Query: 77 IHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVR-DDLGFRLISEQ 135
+ +A+ + +E++ VAAF VS+ ++ RT KPFNPLLGET+EL R ++ G+R + EQ
Sbjct: 460 LDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQ 519
Query: 136 VSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNP 195
VSHHPP +A HAE N + I KF GK + P GTI YTW
Sbjct: 520 VSHHPPAAAHHAES-KNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKV 578
Query: 196 TCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKEL-HKVEGYIQDKSKKK 254
T VHNIIVGKLWI+Q G ++I+NHKTGDKC L F P F +++ KV G + D S K
Sbjct: 579 TTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKV 638
Query: 255 LCALYGKWTECL--YSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVF 312
AL G W E + + V P E +++Q E
Sbjct: 639 HFALLGTWDEKMECFKVQPVI-----------GENGGDARQRGHEAE------------- 674
Query: 313 IIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGE 372
V+LW+ P P N+ MY F+ A+ LN ES TD RLRPD R MENG
Sbjct: 675 --ESRVMLWKRNPLPKNAENMYYFSELALTLNA----WESGTAPTDSRLRPDQRLMENGR 728
Query: 373 IDQASEEKKRLEEKQRAARKNRS----KSEED------WKTRWFHQGPNPYNGAQDWIYS 422
D+A+ EK+RLEEKQR +RK R K+ ED +K WF + +P IY
Sbjct: 729 WDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTPYDPYKALWFERKKDPVTKELTHIYR 788
Query: 423 GSYWD----RNYFNLPDIY 437
G YW+ +++ + PDI+
Sbjct: 789 GEYWECKEKQDWSSCPDIF 807
>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
[Homo sapiens]
Length = 938
Score = 289 bits (740), Expect = 3e-78
Identities = 164/420 (39%), Positives = 230/420 (54%), Gaps = 51/420 (12%)
Query: 10 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTE 69
G A NG R LP+P ++ ++W+ILR IG +LSK++MPV NEPL+ LQ L E
Sbjct: 552 GGAFRNG---RRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCE 608
Query: 70 YMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLG 128
ME++ L+ KAS DP ERM VAAFAVS S + R G KPFNP+LGETYE +R+D G
Sbjct: 609 EMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKG 668
Query: 129 FRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNE 188
FR SEQVSHHPPISA H E N F+F I K KFWGKS+E P GT+ + L ++ +
Sbjct: 669 FRFFSEQVSHHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGD 726
Query: 189 AYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTG-DKCVLNFKPCGLFGKELHKVEGYI 247
Y W T C+HNI+ G+ WIE YG V I N K+ C L F + +++V+G +
Sbjct: 727 YYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVV 786
Query: 248 QDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPD 307
D+ K + L+GKW E LY
Sbjct: 787 IDQEGKAVYRLFGKWHEGLY---------------------------------------- 806
Query: 308 SESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRA 367
+ P + +WR P N Y FT FA+ LNE+D ++ ++P TD R RPD R
Sbjct: 807 ---CGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRF 863
Query: 368 MENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWD 427
+E G ++ A+ EK+R+EE QR+ R+ ++ + ++F + + N + W+ + +YW+
Sbjct: 864 LEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDA-NQREAWVSNDTYWE 922
>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
[Homo sapiens]
Length = 934
Score = 289 bits (740), Expect = 3e-78
Identities = 164/420 (39%), Positives = 230/420 (54%), Gaps = 51/420 (12%)
Query: 10 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTE 69
G A NG R LP+P ++ ++W+ILR IG +LSK++MPV NEPL+ LQ L E
Sbjct: 548 GGAFRNG---RRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCE 604
Query: 70 YMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLG 128
ME++ L+ KAS DP ERM VAAFAVS S + R G KPFNP+LGETYE +R+D G
Sbjct: 605 EMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKG 664
Query: 129 FRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNE 188
FR SEQVSHHPPISA H E N F+F I K KFWGKS+E P GT+ + L ++ +
Sbjct: 665 FRFFSEQVSHHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGD 722
Query: 189 AYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTG-DKCVLNFKPCGLFGKELHKVEGYI 247
Y W T C+HNI+ G+ WIE YG V I N K+ C L F + +++V+G +
Sbjct: 723 YYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVV 782
Query: 248 QDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPD 307
D+ K + L+GKW E LY
Sbjct: 783 IDQEGKAVYRLFGKWHEGLY---------------------------------------- 802
Query: 308 SESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRA 367
+ P + +WR P N Y FT FA+ LNE+D ++ ++P TD R RPD R
Sbjct: 803 ---CGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRF 859
Query: 368 MENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWD 427
+E G ++ A+ EK+R+EE QR+ R+ ++ + ++F + + N + W+ + +YW+
Sbjct: 860 LEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDA-NQREAWVSNDTYWE 918
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 283 bits (724), Expect = 2e-76
Identities = 176/431 (40%), Positives = 228/431 (52%), Gaps = 58/431 (13%)
Query: 19 KHRTSLPS-PMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLI 77
K R +P+ P +S N +WSI++ CIG ELS+I MPV FNEPLS LQRLTE +E+ +L+
Sbjct: 508 KRRVRIPNKPNYSLN---LWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLL 564
Query: 78 HKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVR-DDLGFRLISEQV 136
KA + VE+M VAAF+VS+ ++ R KPFNP+LGET+EL R DD+G R + EQV
Sbjct: 565 DKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQV 624
Query: 137 SHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPT 196
SHHPP SA H + + I KF GK + P G I LE Y W T
Sbjct: 625 SHHPP-SAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKST 683
Query: 197 CCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKE-LHKVEGYIQDKSKKKL 255
VHNIIVGKLWI+Q G++EI+NHKT D+C L F P F KE KV G + D K
Sbjct: 684 STVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAH 743
Query: 256 CALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDS-----ES 310
L G W E QM S+ + P S ++
Sbjct: 744 YVLSGSWDE----------------------------QMECSKVMHSSPSSPSSDGKQKT 775
Query: 311 VFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMEN 370
V+ + LLW+ P P N+ MY F+ A+ LNE + E V P TD RLRPD R ME
Sbjct: 776 VYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHE---EGVAP-TDSRLRPDQRLMEK 831
Query: 371 GEIDQASEEKKRLEEKQRAARKNR--------------SKSEEDWKTRWFHQGPNPYNGA 416
G D+A+ EK+RLEEKQR +R+ R K + + WF + +P G
Sbjct: 832 GRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGE 891
Query: 417 QDWIYSGSYWD 427
+Y G YW+
Sbjct: 892 MACVYKGGYWE 902
>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
Length = 842
Score = 279 bits (714), Expect = 3e-75
Identities = 158/408 (38%), Positives = 223/408 (54%), Gaps = 48/408 (11%)
Query: 21 RTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKA 80
R LP+ D S+W+ILR IG +LSK++MPV NEPL+ LQRL E +E++ L+ +A
Sbjct: 464 RRCLPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQA 523
Query: 81 SSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVSHH 139
S ++DP ERM +AAFAVSA +S + R G KPFNP+LGETYE R D GFR ISEQVSHH
Sbjct: 524 SRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHH 583
Query: 140 PPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCV 199
PPISA HAE N F F + K KFWGKS+E P GT+ + L + + W T C+
Sbjct: 584 PPISACHAESEN--FAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCI 641
Query: 200 HNIIVGKLWIEQYGNVEIINHKTGD-KCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCAL 258
HN++ G+ WIE YG V I N + C + F + +H+V+G + +S + L L
Sbjct: 642 HNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVLHRL 701
Query: 259 YGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSV 318
+GKW E LY PG
Sbjct: 702 FGKWHEGLYRGP-------------------------------------------TPGGQ 718
Query: 319 LLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASE 378
+W+ PP+ + + FT FA+ LNE+ +++ +P TD RLRPD R +E G I A
Sbjct: 719 CIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLRPDQRYLEEGNIQAAEA 778
Query: 379 EKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYW 426
+K+R+E+ QR RK ++ + R+F + + +G + W+ + +YW
Sbjct: 779 QKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDS-SGKEWWVTNNTYW 825
>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
[Homo sapiens]
Length = 847
Score = 142 bits (359), Expect = 5e-34
Identities = 112/386 (29%), Positives = 171/386 (44%), Gaps = 59/386 (15%)
Query: 32 NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 90
N IW++L++ GM+LSK+ +P EP SFL +L++Y H + +A+ +P R+
Sbjct: 361 NKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRL 420
Query: 91 QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 146
+ V + +S + + KP+NP+LGET+ + R + I+EQVSHHPPISAF+
Sbjct: 421 KKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFY 480
Query: 147 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 206
+ F GSI K KF+G S+ A +G L L E Y T P I+ G
Sbjct: 481 VSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGT 540
Query: 207 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKE--LHKVEGYIQDKSKKKLCALYGKWTE 264
+ +E G V I KTG +L FK G ++++ G ++ K+ L L G W
Sbjct: 541 MTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK-LGKEVLATLEGHW-- 597
Query: 265 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 324
D F KK D + E+ P PD + WR+
Sbjct: 598 -----DSEVFITDKKTD---------------NSEVFWNPTPD----------IKQWRLI 627
Query: 325 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLE 384
+ +F E +K + V RA+ + +A++EK LE
Sbjct: 628 RHTVKFEEQGDF--------ESEKLWQRV-----------TRAINAKDQTEATQEKYVLE 668
Query: 385 EKQRAARKNRSKSEEDWKTRWFHQGP 410
E QR A ++R E+W + F P
Sbjct: 669 EAQRQAARDRKTKNEEWSCKLFELDP 694
>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
Length = 889
Score = 142 bits (359), Expect = 5e-34
Identities = 112/386 (29%), Positives = 171/386 (44%), Gaps = 59/386 (15%)
Query: 32 NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 90
N IW++L++ GM+LSK+ +P EP SFL +L++Y H + +A+ +P R+
Sbjct: 403 NKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRL 462
Query: 91 QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 146
+ V + +S + + KP+NP+LGET+ + R + I+EQVSHHPPISAF+
Sbjct: 463 KKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFY 522
Query: 147 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 206
+ F GSI K KF+G S+ A +G L L E Y T P I+ G
Sbjct: 523 VSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGT 582
Query: 207 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKE--LHKVEGYIQDKSKKKLCALYGKWTE 264
+ +E G V I KTG +L FK G ++++ G ++ K+ L L G W
Sbjct: 583 MTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK-LGKEVLATLEGHW-- 639
Query: 265 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 324
D F KK D + E+ P PD + WR+
Sbjct: 640 -----DSEVFITDKKTD---------------NSEVFWNPTPD----------IKQWRLI 669
Query: 325 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLE 384
+ +F E +K + V RA+ + +A++EK LE
Sbjct: 670 RHTVKFEEQGDF--------ESEKLWQRV-----------TRAINAKDQTEATQEKYVLE 710
Query: 385 EKQRAARKNRSKSEEDWKTRWFHQGP 410
E QR A ++R E+W + F P
Sbjct: 711 EAQRQAARDRKTKNEEWSCKLFELDP 736
>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
[Homo sapiens]
Length = 879
Score = 139 bits (349), Expect = 7e-33
Identities = 117/407 (28%), Positives = 175/407 (42%), Gaps = 68/407 (16%)
Query: 32 NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 90
N +W++L++ GM+LS++ +P EP SFL +L++Y H L+ +A+ D RM
Sbjct: 367 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM 426
Query: 91 QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 146
+ V + +S + + KP+NP+LGET+ + D I+EQVSHHPP+SAFH
Sbjct: 427 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH 486
Query: 147 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 206
+ F GSI K +F+G S+ A G TL L E YT T P I+ G
Sbjct: 487 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT 546
Query: 207 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFG--KELHKVEGYIQDKSKKKLCALYGKWTE 264
+ +E G V I K + L FK FG ++++ G I ++ L +L G W
Sbjct: 547 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR 605
Query: 265 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 324
D + K + + S L W
Sbjct: 606 ----------DVFIKEEGSGS-------------------------------SALFW--- 621
Query: 325 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDI-RAMENGEIDQASEEKKRL 383
P + + L E ++ES RL + RA+ G+ +A++EK L
Sbjct: 622 -TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFAL 673
Query: 384 EEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY---SGSYWD 427
EE QR + R +S WK + FH P Q+W Y S WD
Sbjct: 674 EEAQRQRARERQESLMPWKPQLFHLDPI----TQEWHYRYEDHSPWD 716
>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 139 bits (349), Expect = 7e-33
Identities = 117/407 (28%), Positives = 175/407 (42%), Gaps = 68/407 (16%)
Query: 32 NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 90
N +W++L++ GM+LS++ +P EP SFL +L++Y H L+ +A+ D RM
Sbjct: 299 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM 358
Query: 91 QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 146
+ V + +S + + KP+NP+LGET+ + D I+EQVSHHPP+SAFH
Sbjct: 359 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH 418
Query: 147 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 206
+ F GSI K +F+G S+ A G TL L E YT T P I+ G
Sbjct: 419 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT 478
Query: 207 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFG--KELHKVEGYIQDKSKKKLCALYGKWTE 264
+ +E G V I K + L FK FG ++++ G I ++ L +L G W
Sbjct: 479 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR 537
Query: 265 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 324
D + K + + S L W
Sbjct: 538 ----------DVFIKEEGSGS-------------------------------SALFW--- 553
Query: 325 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDI-RAMENGEIDQASEEKKRL 383
P + + L E ++ES RL + RA+ G+ +A++EK L
Sbjct: 554 -TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFAL 605
Query: 384 EEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY---SGSYWD 427
EE QR + R +S WK + FH P Q+W Y S WD
Sbjct: 606 EEAQRQRARERQESLMPWKPQLFHLDPI----TQEWHYRYEDHSPWD 648
>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 139 bits (349), Expect = 7e-33
Identities = 117/407 (28%), Positives = 175/407 (42%), Gaps = 68/407 (16%)
Query: 32 NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 90
N +W++L++ GM+LS++ +P EP SFL +L++Y H L+ +A+ D RM
Sbjct: 299 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM 358
Query: 91 QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 146
+ V + +S + + KP+NP+LGET+ + D I+EQVSHHPP+SAFH
Sbjct: 359 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH 418
Query: 147 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 206
+ F GSI K +F+G S+ A G TL L E YT T P I+ G
Sbjct: 419 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT 478
Query: 207 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFG--KELHKVEGYIQDKSKKKLCALYGKWTE 264
+ +E G V I K + L FK FG ++++ G I ++ L +L G W
Sbjct: 479 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI-TSGEEVLASLSGHWDR 537
Query: 265 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 324
D + K + + S L W
Sbjct: 538 ----------DVFIKEEGSGS-------------------------------SALFW--- 553
Query: 325 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDI-RAMENGEIDQASEEKKRL 383
P + + L E ++ES RL + RA+ G+ +A++EK L
Sbjct: 554 -TPSGEVRRQRLRQHTVPLEE-QTELESE------RLWQHVTRAISKGDQHRATQEKFAL 605
Query: 384 EEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY---SGSYWD 427
EE QR + R +S WK + FH P Q+W Y S WD
Sbjct: 606 EEAQRQRARERQESLMPWKPQLFHLDPI----TQEWHYRYEDHSPWD 648
>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
Length = 736
Score = 124 bits (310), Expect = 2e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
Query: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 444 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 503
Query: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 504 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 563
Query: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 564 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 622
Query: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
G+W +Y+ + + KK KK +++ E + S
Sbjct: 623 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 667
Query: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
LW+ D IR +ID A+E
Sbjct: 668 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 687
Query: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 688 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 723
>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
sapiens]
Length = 746
Score = 124 bits (310), Expect = 2e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 394 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 453
Query: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 454 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 513
Query: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 514 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 573
Query: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 574 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 632
Query: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
G+W +Y+ + + KK KK +++ E + S
Sbjct: 633 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 677
Query: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
LW+ D IR +ID A+E
Sbjct: 678 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 697
Query: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 698 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 733
>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
sapiens]
Length = 723
Score = 124 bits (310), Expect = 2e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 371 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 430
Query: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 431 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 490
Query: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 491 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 550
Query: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 551 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 609
Query: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
G+W +Y+ + + KK KK +++ E + S
Sbjct: 610 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 654
Query: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
LW+ D IR +ID A+E
Sbjct: 655 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 674
Query: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 675 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 710
>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
sapiens]
Length = 626
Score = 124 bits (310), Expect = 2e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 274 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 333
Query: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 334 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 393
Query: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 394 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 453
Query: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 454 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 512
Query: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
G+W +Y+ + + KK KK +++ E + S
Sbjct: 513 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 557
Query: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
LW+ D IR +ID A+E
Sbjct: 558 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 577
Query: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 578 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 613
>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
sapiens]
Length = 571
Score = 124 bits (310), Expect = 2e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 219 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 278
Query: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 279 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 338
Query: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 339 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 398
Query: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 399 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 457
Query: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
G+W +Y+ + + KK KK +++ E + S
Sbjct: 458 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 502
Query: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
LW+ D IR +ID A+E
Sbjct: 503 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 522
Query: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 523 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 558
>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 124 bits (310), Expect = 2e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 206 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 265
Query: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 266 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 325
Query: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 326 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 385
Query: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 386 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 444
Query: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
G+W +Y+ + + KK KK +++ E + S
Sbjct: 445 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 489
Query: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
LW+ D IR +ID A+E
Sbjct: 490 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 509
Query: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 545
>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 124 bits (310), Expect = 2e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 206 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 265
Query: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 266 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 325
Query: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 326 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 385
Query: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 386 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 444
Query: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
G+W +Y+ + + KK KK +++ E + S
Sbjct: 445 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 489
Query: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
LW+ D IR +ID A+E
Sbjct: 490 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 509
Query: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 545
>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
Length = 747
Score = 110 bits (276), Expect = 2e-24
Identities = 96/422 (22%), Positives = 161/422 (38%), Gaps = 102/422 (24%)
Query: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAV-- 101
+GM+L+++ +P E S L+ ++M H L ++ + +RM + +++
Sbjct: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
Query: 102 ASQWERTGKPFNPLLGETY------------------------------------ELVRD 125
+ KP+NP++GET+ ++ D
Sbjct: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
Query: 126 DLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLE 185
R ++EQVSHHPP+S F+AE + ++ K KF G S+ G L LLE
Sbjct: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
Query: 186 HNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG 245
H E YT++ P C I+ W+E G V + KTG + F +G +LH+V
Sbjct: 559 HGEEYTFSLP-CAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTA 617
Query: 246 YIQDK-SKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMP 304
++ + +C + G+W L Y + K + K + L++
Sbjct: 618 EVKHNITNTVVCRVQGEWNSVLEF-------TYSNGETKYVDLTKLAVTKKRVRPLEKQD 670
Query: 305 VPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPD 364
+S LW+ N D ES
Sbjct: 671 PFESRR---------LWK---------------------NVTDSLRES------------ 688
Query: 365 IRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGS 424
EID+A+E K LEE+QR ++R+++ WKT++F W+Y
Sbjct: 689 -------EIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF------IKEGDGWVYHKP 735
Query: 425 YW 426
W
Sbjct: 736 LW 737
>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
sapiens]
Length = 764
Score = 107 bits (268), Expect = 2e-23
Identities = 86/326 (26%), Positives = 142/326 (43%), Gaps = 48/326 (14%)
Query: 11 DALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEY 70
D S+ K T L M + + I + +GM+L+K+ +P E S L+ ++
Sbjct: 377 DEKSDNEDKEETEL-GVMEDQRSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADF 435
Query: 71 MEHTYLIHKASSLSDPVERMQCVAAFAVSAV--ASQWERTGKPFNPLLGETY----ELVR 124
M H L+ ++ + P ER+ C + ++A + KP+NP++GET+ E+ +
Sbjct: 436 MAHPDLLLAITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPK 495
Query: 125 DDLG--------------------------FRLISEQVSHHPPISAFHAEGLNNDFIFHG 158
D + R ++EQVSHHPPIS F+ E +
Sbjct: 496 DRVKPKRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNT 555
Query: 159 SIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEII 218
++ K KF G SV G L LLEH E Y +T P+ +I+ W+E G V I
Sbjct: 556 HVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIP-WVELGGKVSIN 614
Query: 219 NHKTGDKCVLNFKPCGLFGKELHKVEGYIQ-DKSKKKLCALYGKWT---ECLYS------ 268
KTG + F +G ++H+V ++ + + +C +G+W E Y+
Sbjct: 615 CAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKV 674
Query: 269 VDPATFDAYKKN----DKKNTEEKKN 290
+D T Y K +K+ E +N
Sbjct: 675 IDTTTLPVYPKKIRPLEKQGPMESRN 700
Score = 44.7 bits (104), Expect = 2e-04
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
Query: 366 RAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425
R + G+ID A+E+K+ LEEKQR + R WK ++F Q W+Y
Sbjct: 707 RYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQ------EGDGWVYFNPL 760
Query: 426 W 426
W
Sbjct: 761 W 761
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 36.6 bits (83), Expect = 0.046
Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 12/134 (8%)
Query: 275 DAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSE--SVFIIPGSVLLWR--IAPRPPNS 330
D ++ KK E+++ + S SEE D+ + E S+ +PG L R + + N
Sbjct: 304 DHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENK 363
Query: 331 AQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAA 390
+ + + +D E+ I + I++ EE++R+EE+QR
Sbjct: 364 SNSEALKQQQQLQQQQQRDPEAHIKH--------LLHQRQRRIEEQKEERRRVEEQQRRE 415
Query: 391 RKNRSKSEEDWKTR 404
R+ R E++ + R
Sbjct: 416 REQRKLQEKEQQRR 429
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 36.6 bits (83), Expect = 0.046
Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 12/134 (8%)
Query: 275 DAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSE--SVFIIPGSVLLWR--IAPRPPNS 330
D ++ KK E+++ + S SEE D+ + E S+ +PG L R + + N
Sbjct: 304 DHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENK 363
Query: 331 AQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAA 390
+ + + +D E+ I + I++ EE++R+EE+QR
Sbjct: 364 SNSEALKQQQQLQQQQQRDPEAHIKH--------LLHQRQRRIEEQKEERRRVEEQQRRE 415
Query: 391 RKNRSKSEEDWKTR 404
R+ R E++ + R
Sbjct: 416 REQRKLQEKEQQRR 429
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 36.6 bits (83), Expect = 0.046
Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 12/134 (8%)
Query: 275 DAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSE--SVFIIPGSVLLWR--IAPRPPNS 330
D ++ KK E+++ + S SEE D+ + E S+ +PG L R + + N
Sbjct: 304 DHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENK 363
Query: 331 AQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAA 390
+ + + +D E+ I + I++ EE++R+EE+QR
Sbjct: 364 SNSEALKQQQQLQQQQQRDPEAHIKH--------LLHQRQRRIEEQKEERRRVEEQQRRE 415
Query: 391 RKNRSKSEEDWKTR 404
R+ R E++ + R
Sbjct: 416 REQRKLQEKEQQRR 429
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,564,080
Number of Sequences: 37866
Number of extensions: 857806
Number of successful extensions: 3944
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 3754
Number of HSP's gapped (non-prelim): 153
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.