Guide to the Human Genome
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Search of human proteins with 195947397

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]
         (463 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]                919   0.0  
gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]                  913   0.0  
gi|156105679 presenilin 2 isoform 1 [Homo sapiens]                    553   e-157
gi|156105681 presenilin 2 isoform 2 [Homo sapiens]                    551   e-157
gi|68223315 CD47 antigen isoform 3 precursor [Homo sapiens]            42   0.002
gi|38683836 CD47 antigen isoform 2 precursor [Homo sapiens]            42   0.002
gi|4502673 CD47 antigen isoform 1 precursor [Homo sapiens]             42   0.002
gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b...    34   0.32 
gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform...    34   0.32 
gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo ...    32   1.2  
gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo ...    32   1.2  
gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo ...    32   1.2  
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       31   2.1  
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       31   2.1  
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       31   2.1  
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        31   2.1  
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]       31   2.7  
gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]            31   2.7  
gi|18034692 CDW92 antigen [Homo sapiens]                               31   2.7  
gi|4505999 protein phosphatase 1G [Homo sapiens]                       30   3.5  
gi|29826282 protein phosphatase 1G [Homo sapiens]                      30   3.5  
gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo sapi...    30   4.6  
gi|7706704 G protein-coupled receptor 89B [Homo sapiens]               30   4.6  
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       30   4.6  
gi|94721321 coiled-coil domain containing 11 [Homo sapiens]            30   4.6  
gi|52218862 olfactory receptor, family 13, subfamily J, member 1...    30   4.6  
gi|57977305 G protein-coupled receptor 151 [Homo sapiens]              30   4.6  
gi|21735492 protein phosphatase 1, regulatory (inhibitor) subuni...    30   6.0  
gi|4502805 chromogranin A precursor [Homo sapiens]                     30   6.0  
gi|31415880 protein phosphatase 1, regulatory (inhibitor) subuni...    30   6.0  

>gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]
          Length = 463

 Score =  919 bits (2375), Expect = 0.0
 Identities = 463/463 (100%), Positives = 463/463 (100%)

Query: 1   MTELPAPLSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVE 60
           MTELPAPLSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVE
Sbjct: 1   MTELPAPLSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVE 60

Query: 61  QDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTET 120
           QDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTET
Sbjct: 61  QDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTET 120

Query: 121 VGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGE 180
           VGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGE
Sbjct: 121 VGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGE 180

Query: 181 VFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEW 240
           VFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEW
Sbjct: 181 VFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEW 240

Query: 241 TAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPE 300
           TAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPE
Sbjct: 241 TAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPE 300

Query: 301 AQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQEL 360
           AQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQEL
Sbjct: 301 AQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQEL 360

Query: 361 SSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLL 420
           SSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLL
Sbjct: 361 SSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLL 420

Query: 421 LAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 463
           LAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
Sbjct: 421 LAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 463


>gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]
          Length = 467

 Score =  913 bits (2360), Expect = 0.0
 Identities = 463/467 (99%), Positives = 463/467 (99%), Gaps = 4/467 (0%)

Query: 1   MTELPAPLSYFQNAQMSEDNHLSNT----NDNRERQEHNDRRSLGHPEPLSNGRPQGNSR 56
           MTELPAPLSYFQNAQMSEDNHLSNT    NDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
Sbjct: 1   MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR 60

Query: 57  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE 116
           QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
Sbjct: 61  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE 120

Query: 117 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI 176
           DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
Sbjct: 121 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI 180

Query: 177 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY 236
           YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
Sbjct: 181 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY 240

Query: 237 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE 296
           LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
Sbjct: 241 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE 300

Query: 297 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA 356
           GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
Sbjct: 301 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA 360

Query: 357 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL 416
           VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
Sbjct: 361 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL 420

Query: 417 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 463
           TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
Sbjct: 421 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 467


>gi|156105679 presenilin 2 isoform 1 [Homo sapiens]
          Length = 448

 Score =  553 bits (1425), Expect = e-157
 Identities = 303/464 (65%), Positives = 343/464 (73%), Gaps = 42/464 (9%)

Query: 3   ELPAPLSYFQNAQMSEDNHLS---NTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVV 59
           E P P S  +  Q  ED   +    + +N E  E +  R +    P   GRP G      
Sbjct: 24  ESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGVP---GRPPGL----- 75

Query: 60  EQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTE 119
                 +EELTLKYGAKHVIMLFVPVTLCM+VVVATIKSV FYT K+GQLIYTPFTEDT 
Sbjct: 76  ------EEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTP 129

Query: 120 TVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLG 179
           +VGQR L+S+LN  IMISVIVVMTI LVVLYKYRCYK IH WLI+SSL+LLF F++IYLG
Sbjct: 130 SVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLG 189

Query: 180 EVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPE 239
           EV KTYNVA+DY T+ L +WNFG VGM+ IHWKGPL LQQAYLIMISALMALVFIKYLPE
Sbjct: 190 EVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPE 249

Query: 240 WTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDP 299
           W+AW+IL  ISVYDLVAVLCPKGPLRMLVETAQERNE +FPALIYSS MVW V MA+ DP
Sbjct: 250 WSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDP 309

Query: 300 EAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQE 359
            +Q  +     Y+ E  E +S D+  E     + E +E     + G            +E
Sbjct: 310 SSQGAL--QLPYDPE-MEEDSYDSFGE---PSYPEVFEPPLTGYPG------------EE 351

Query: 360 LSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLL 419
           L       E+ EERGVKLGLGDFIFYSVLVGKA+AT SGDWNTT+ACFVAILIGLCLTLL
Sbjct: 352 L-------EEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLL 404

Query: 420 LLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 463
           LLA+FKKALPALPISITFGL+FYF+TD LV+PFMD LA HQ YI
Sbjct: 405 LLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448


>gi|156105681 presenilin 2 isoform 2 [Homo sapiens]
          Length = 447

 Score =  551 bits (1420), Expect = e-157
 Identities = 299/464 (64%), Positives = 340/464 (73%), Gaps = 43/464 (9%)

Query: 3   ELPAPLSYFQNAQMSEDNHLS---NTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVV 59
           E P P S  +  Q  ED   +    + +N E  E +  R +    P   GRP G      
Sbjct: 24  ESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGVP---GRPPGL----- 75

Query: 60  EQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTE 119
                 +EELTLKYGAKHVIMLFVPVTLCM+VVVATIKSV FYT K+GQLIYTPFTEDT 
Sbjct: 76  ------EEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTP 129

Query: 120 TVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLG 179
           +VGQR L+S+LN  IMISVIVVMTI LVVLYKYRCYK IH WLI+SSL+LLF F++IYLG
Sbjct: 130 SVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLG 189

Query: 180 EVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPE 239
           EV KTYNVA+DY T+ L +WNFG VGM+ IHWKGPL LQQAYLIMISALMALVFIKYLPE
Sbjct: 190 EVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPE 249

Query: 240 WTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDP 299
           W+AW+IL  ISVYDLVAVLCPKGPLRMLVETAQERNE +FPALIYSS MVW V MA+ DP
Sbjct: 250 WSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDP 309

Query: 300 EAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQE 359
            +Q  +           + E +D+     +  + E +E     + G            +E
Sbjct: 310 SSQGALQL-------PYDPEMEDSYDSFGEPSYPEVFEPPLTGYPG------------EE 350

Query: 360 LSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLL 419
           L       E+ EERGVKLGLGDFIFYSVLVGKA+AT SGDWNTT+ACFVAILIGLCLTLL
Sbjct: 351 L-------EEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLL 403

Query: 420 LLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 463
           LLA+FKKALPALPISITFGL+FYF+TD LV+PFMD LA HQ YI
Sbjct: 404 LLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 447


>gi|68223315 CD47 antigen isoform 3 precursor [Homo sapiens]
          Length = 312

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/187 (20%), Positives = 83/187 (44%), Gaps = 15/187 (8%)

Query: 57  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLI-YTPFT 115
           +V E   E +  + LKY    V+  F P    ++V+      + F+ +   + + Y    
Sbjct: 115 EVTELTREGETIIELKY---RVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGG 171

Query: 116 EDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSF 175
            D +T+      ++L A ++I+VIV++  +L V  +Y         LI++S  +L    +
Sbjct: 172 MDEKTI------ALLVAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHY 225

Query: 176 IYLGEVFKTYNVAVDYITVALLIWNFGVVGM-----ISIHWKGPLRLQQAYLIMISALMA 230
                     +  +  + + ++ +   VVG+       I   GPL +    ++ ++ L+ 
Sbjct: 226 YVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLG 285

Query: 231 LVFIKYL 237
           LV++K++
Sbjct: 286 LVYMKFV 292


>gi|38683836 CD47 antigen isoform 2 precursor [Homo sapiens]
          Length = 305

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/187 (20%), Positives = 83/187 (44%), Gaps = 15/187 (8%)

Query: 57  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLI-YTPFT 115
           +V E   E +  + LKY    V+  F P    ++V+      + F+ +   + + Y    
Sbjct: 115 EVTELTREGETIIELKY---RVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGG 171

Query: 116 EDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSF 175
            D +T+      ++L A ++I+VIV++  +L V  +Y         LI++S  +L    +
Sbjct: 172 MDEKTI------ALLVAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHY 225

Query: 176 IYLGEVFKTYNVAVDYITVALLIWNFGVVGM-----ISIHWKGPLRLQQAYLIMISALMA 230
                     +  +  + + ++ +   VVG+       I   GPL +    ++ ++ L+ 
Sbjct: 226 YVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLG 285

Query: 231 LVFIKYL 237
           LV++K++
Sbjct: 286 LVYMKFV 292


>gi|4502673 CD47 antigen isoform 1 precursor [Homo sapiens]
          Length = 323

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/187 (20%), Positives = 83/187 (44%), Gaps = 15/187 (8%)

Query: 57  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLI-YTPFT 115
           +V E   E +  + LKY    V+  F P    ++V+      + F+ +   + + Y    
Sbjct: 115 EVTELTREGETIIELKY---RVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGG 171

Query: 116 EDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSF 175
            D +T+      ++L A ++I+VIV++  +L V  +Y         LI++S  +L    +
Sbjct: 172 MDEKTI------ALLVAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHY 225

Query: 176 IYLGEVFKTYNVAVDYITVALLIWNFGVVGM-----ISIHWKGPLRLQQAYLIMISALMA 230
                     +  +  + + ++ +   VVG+       I   GPL +    ++ ++ L+ 
Sbjct: 226 YVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLG 285

Query: 231 LVFIKYL 237
           LV++K++
Sbjct: 286 LVYMKFV 292


>gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b
           [Homo sapiens]
          Length = 933

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 3/119 (2%)

Query: 261 KGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERES 320
           K  LR  V T  + +  L    +Y+S   W   + E D + +   +   K + E  E ES
Sbjct: 414 KSMLRPEVGTTSQ-DSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEES 472

Query: 321 QDTVAENDDGGFSEEWEAQR-DSHLGPHRSTPESRAAVQELSSSILAGE-DPEERGVKL 377
           +  V  + +   +   E +    +L PH   P+ +A V+ LS+++ A   D  E  + +
Sbjct: 473 EGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISI 531


>gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform a
           [Homo sapiens]
          Length = 950

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 3/119 (2%)

Query: 261 KGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERES 320
           K  LR  V T  + +  L    +Y+S   W   + E D + +   +   K + E  E ES
Sbjct: 431 KSMLRPEVGTTSQ-DSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEES 489

Query: 321 QDTVAENDDGGFSEEWEAQR-DSHLGPHRSTPESRAAVQELSSSILAGE-DPEERGVKL 377
           +  V  + +   +   E +    +L PH   P+ +A V+ LS+++ A   D  E  + +
Sbjct: 490 EGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISI 548


>gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo
           sapiens]
          Length = 426

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 377 LGLGDF----IFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL- 431
           LGLGD     IF ++L+    +            F A + GL LT+ ++ IFK A PAL 
Sbjct: 261 LGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALL 320

Query: 432 ---PISITFGLVFYFATDYLVQPF 452
              P  I F ++   A   + + F
Sbjct: 321 YLVPACIGFPVLVALAKGEVTEMF 344


>gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo
           sapiens]
          Length = 394

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 377 LGLGDF----IFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL- 431
           LGLGD     IF ++L+    +            F A + GL LT+ ++ IFK A PAL 
Sbjct: 261 LGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALL 320

Query: 432 ---PISITFGLVFYFATDYLVQPF 452
              P  I F ++   A   + + F
Sbjct: 321 YLVPACIGFPVLVALAKGEVTEMF 344


>gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo
           sapiens]
          Length = 377

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 377 LGLGDF----IFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL- 431
           LGLGD     IF ++L+    +            F A + GL LT+ ++ IFK A PAL 
Sbjct: 261 LGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALL 320

Query: 432 ---PISITFGLVFYFATDYLVQPF 452
              P  I F ++   A   + + F
Sbjct: 321 YLVPACIGFPVLVALAKGEVTEMF 344


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 16/61 (26%), Positives = 28/61 (45%)

Query: 8  LSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDE 67
          +S  +++  SE+     ++D  E +   +RRS    E       +    +  E DEEE+E
Sbjct: 1  MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 68 E 68
          E
Sbjct: 61 E 61


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 16/61 (26%), Positives = 28/61 (45%)

Query: 8  LSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDE 67
          +S  +++  SE+     ++D  E +   +RRS    E       +    +  E DEEE+E
Sbjct: 1  MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 68 E 68
          E
Sbjct: 61 E 61


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 16/61 (26%), Positives = 28/61 (45%)

Query: 8  LSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDE 67
          +S  +++  SE+     ++D  E +   +RRS    E       +    +  E DEEE+E
Sbjct: 1  MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 68 E 68
          E
Sbjct: 61 E 61


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 16/61 (26%), Positives = 28/61 (45%)

Query: 8  LSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDE 67
          +S  +++  SE+     ++D  E +   +RRS    E       +    +  E DEEE+E
Sbjct: 1  MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 68 E 68
          E
Sbjct: 61 E 61


>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
          Length = 1134

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 34/159 (21%), Positives = 61/159 (38%), Gaps = 39/159 (24%)

Query: 135  MISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITV 194
            ++  ++V T+ L +      +  I+ ++I  SLL    FS ++ G               
Sbjct: 1007 LVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGG--------------- 1051

Query: 195  ALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDL 254
              +IW F             L  Q+ Y          VFI+ L    AWL + ++    L
Sbjct: 1052 --VIWPF-------------LNYQRMYY---------VFIQMLSSGPAWLAIVLLVTISL 1087

Query: 255  VAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVN 293
            +  +  K   R L  TA ER +T    L    + +++++
Sbjct: 1088 LPDVLKKVLCRQLWPTATERVQTKSQCLSVEQSTIFMLS 1126


>gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]
          Length = 520

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 3/58 (5%)

Query: 377 LGLGDFIFYSVLVG---KASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL 431
           LG GD I   +L+    +        +   ++  VA  IG+ LT ++L + KK  PAL
Sbjct: 408 LGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPAL 465


>gi|18034692 CDW92 antigen [Homo sapiens]
          Length = 657

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 38/235 (16%), Positives = 93/235 (39%), Gaps = 12/235 (5%)

Query: 47  SNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKD 106
           + G P  N +  VE       +    Y    +I +   +  C  + VA      ++TR  
Sbjct: 361 TTGSPVQNEQGFVEFKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDK 420

Query: 107 GQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLY------KYRCYKVIHA 160
             L +TP       + +  L ++   + +I+++ +  ++L+ ++      +  C + +  
Sbjct: 421 RNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGKENACARCVLK 480

Query: 161 WLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVA-----LLIWNFGVVGMISIHWKGPL 215
             I     L    +++       T   + ++ T A     +L+ N   V  I+      L
Sbjct: 481 SCICCLWCLEKCLNYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVATINTVGDFML 540

Query: 216 RLQQAYLIMISALMALVFIKYLPEWTAWLI-LAVISVYDLVAVLCPKGPLRMLVE 269
            L +  ++  + L  ++ + Y  ++T W++ L ++ ++  +   C      M+V+
Sbjct: 541 FLGKVLIVCSTGLAGIMLLNYQQDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVD 595


>gi|4505999 protein phosphatase 1G [Homo sapiens]
          Length = 546

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 6   APLSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEE 65
           A   +F++++   D       D+ E  E  D  S    E   N   + ++ +  E DEEE
Sbjct: 252 AKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYS---SEEAENEEDEDDTEEAEEDDEEE 308

Query: 66  DEEL 69
           +EE+
Sbjct: 309 EEEM 312


>gi|29826282 protein phosphatase 1G [Homo sapiens]
          Length = 546

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 6   APLSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEE 65
           A   +F++++   D       D+ E  E  D  S    E   N   + ++ +  E DEEE
Sbjct: 252 AKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYS---SEEAENEEDEDDTEEAEEDDEEE 308

Query: 66  DEEL 69
           +EE+
Sbjct: 309 EEEM 312


>gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo
           sapiens]
          Length = 455

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 18/85 (21%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 124 RALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIY--LGEV 181
           R  H  +N  +++ ++V M    +  +     +++H   ++ S LL   F + +  LG+ 
Sbjct: 71  RYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTFMYFFWKLGDP 130

Query: 182 FKTYNVAVDYITVALLIWNFGVVGM 206
           F   +     +++  LI   GV+G+
Sbjct: 131 FPILSPKHGILSIEQLISRVGVIGV 155


>gi|7706704 G protein-coupled receptor 89B [Homo sapiens]
          Length = 455

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 18/85 (21%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 124 RALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIY--LGEV 181
           R  H  +N  +++ ++V M    +  +     +++H   ++ S LL   F + +  LG+ 
Sbjct: 71  RYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTFMYFFWKLGDP 130

Query: 182 FKTYNVAVDYITVALLIWNFGVVGM 206
           F   +     +++  LI   GV+G+
Sbjct: 131 FPILSPKHGILSIEQLISRVGVIGV 155


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 15/68 (22%), Positives = 32/68 (47%)

Query: 1    MTELPAPLSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVE 60
            M E P+ LS     Q + ++ ++  +   E +   +  S G  E   + + +    +  E
Sbjct: 2383 MDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDE 2442

Query: 61   QDEEEDEE 68
            +D++ED+E
Sbjct: 2443 EDDQEDDE 2450


>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
          Length = 514

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 300 EAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRS--TPESRAAV 357
           E + R+ + +K   E  E+E QD VAE  D  F E  E  R   L  H+     E +A +
Sbjct: 125 EKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRVELLSIHQKKVCEERKAQI 184

Query: 358 ---QELSSSILAGE 368
              +ELS   L  E
Sbjct: 185 AFNEELSRQKLVEE 198


>gi|52218862 olfactory receptor, family 13, subfamily J, member 1
           [Homo sapiens]
          Length = 312

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 112 TPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLF 171
           T  +ED    G   L  +  A I +S ++++  +L V    RC K     L   +++LLF
Sbjct: 192 TSVSEDFLLAGSILLLPVPLAFICLSYLLILATILRVPSAARCCKAFSTCLAHLAVVLLF 251

Query: 172 FFS--FIYLGEVFKTYNVAVDYITV 194
           + +  F+YL    K  +++ +  TV
Sbjct: 252 YGTIIFMYLKPKSKEAHISDEVFTV 276


>gi|57977305 G protein-coupled receptor 151 [Homo sapiens]
          Length = 419

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 16/110 (14%)

Query: 223 IMISALMALVFIKYLPEWTAWLILAVISVYDLVAV--LCPKGPLRMLVETAQERNETLFP 280
           +M+ ++  +  + +LPEW AWL      V+ L A     P+G + +        ++ L  
Sbjct: 250 VMLLSIAIISALLWLPEWVAWL-----WVWHLKAAGPAPPQGFIAL--------SQVLMF 296

Query: 281 ALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDG 330
           ++  ++ +++LV M+E   E  + V K        T  ESQ+T A N +G
Sbjct: 297 SISSANPLIFLV-MSEEFREGLKGVWKWMITKKPPTVSESQETPAGNSEG 345


>gi|21735492 protein phosphatase 1, regulatory (inhibitor) subunit
           1B isoform 1 [Homo sapiens]
          Length = 204

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 15/67 (22%)

Query: 5   PAPLSYFQNAQMSEDNHLSNTNDNR---ERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQ 61
           P  L   Q    S    +SN N+N+   E  E  + R LG+P            R+  E+
Sbjct: 76  PPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYP------------REEDEE 123

Query: 62  DEEEDEE 68
           +EE+DEE
Sbjct: 124 EEEDDEE 130


>gi|4502805 chromogranin A precursor [Homo sapiens]
          Length = 457

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 14/55 (25%), Positives = 29/55 (52%), Gaps = 4/55 (7%)

Query: 17  SEDNHLSNTNDNRERQEHNDR----RSLGHPEPLSNGRPQGNSRQVVEQDEEEDE 67
           S  + +    D++E ++  +     R    PEP+   + +GN++   E++EEE+E
Sbjct: 125 SSKDVMEKREDSKEAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEE 179


>gi|31415880 protein phosphatase 1, regulatory (inhibitor) subunit
          1B isoform 2 [Homo sapiens]
          Length = 168

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 15/67 (22%)

Query: 5  PAPLSYFQNAQMSEDNHLSNTNDNR---ERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQ 61
          P  L   Q    S    +SN N+N+   E  E  + R LG+P            R+  E+
Sbjct: 40 PPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYP------------REEDEE 87

Query: 62 DEEEDEE 68
          +EE+DEE
Sbjct: 88 EEEDDEE 94


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,556,402
Number of Sequences: 37866
Number of extensions: 704466
Number of successful extensions: 3209
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3153
Number of HSP's gapped (non-prelim): 59
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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