Guide to the Human Genome
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Search of human proteins with 195947361

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195947361 histidine acid phosphatase domain containing 2A
isoform 2 [Homo sapiens]
         (1408 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195947361 histidine acid phosphatase domain containing 2A iso...  2841   0.0  
gi|66932992 histidine acid phosphatase domain containing 2A isof...  2841   0.0  
gi|195947359 histidine acid phosphatase domain containing 2A iso...  2823   0.0  
gi|66932994 histidine acid phosphatase domain containing 2A isof...  1724   0.0  
gi|41281583 Histidine acid phosphatase domain containing 1 [Homo...  1574   0.0  
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    46   2e-04
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             44   0.001
gi|149999615 variable charge, X-linked 3B [Homo sapiens]               41   0.007
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]         40   0.016
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        40   0.016
gi|221139761 zinc finger protein 853 [Homo sapiens]                    39   0.027
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             39   0.027
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       39   0.027
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s...    39   0.027
gi|161019170 mucin 5AC [Homo sapiens]                                  39   0.035
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...    39   0.035
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...    39   0.035
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    39   0.035
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]          39   0.035
gi|110665701 leucine rich repeat containing 37A [Homo sapiens]         39   0.035
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    39   0.046
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                39   0.046
gi|59853352 myosin VIIA and Rab interacting protein [Homo sapiens]     38   0.060
gi|122937239 zinc finger CCCH-type domain containing 5 [Homo sap...    38   0.079
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]                  37   0.10 
gi|146134388 YLP motif containing 1 [Homo sapiens]                     37   0.10 
gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]               37   0.13 
gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]               37   0.13 
gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]                37   0.13 
gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]               37   0.13 

>gi|195947361 histidine acid phosphatase domain containing 2A isoform
            2 [Homo sapiens]
          Length = 1408

 Score = 2841 bits (7364), Expect = 0.0
 Identities = 1408/1408 (100%), Positives = 1408/1408 (100%)

Query: 1    MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 60
            MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC
Sbjct: 1    MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 60

Query: 61   AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 120
            AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK
Sbjct: 61   AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 120

Query: 121  AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 180
            AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG
Sbjct: 121  AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 180

Query: 181  EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 240
            EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR
Sbjct: 181  EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 240

Query: 241  KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 300
            KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM
Sbjct: 241  KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 300

Query: 301  EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 360
            EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE
Sbjct: 301  EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 360

Query: 361  LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 420
            LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA
Sbjct: 361  LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 420

Query: 421  LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 480
            LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY
Sbjct: 421  LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 480

Query: 481  GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 540
            GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR
Sbjct: 481  GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 540

Query: 541  AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 600
            AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL
Sbjct: 541  AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 600

Query: 601  TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 660
            TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS
Sbjct: 601  TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 660

Query: 661  LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 720
            LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE
Sbjct: 661  LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 720

Query: 721  RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 780
            RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR
Sbjct: 721  RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 780

Query: 781  EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 840
            EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH
Sbjct: 781  EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 840

Query: 841  VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 900
            VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH
Sbjct: 841  VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 900

Query: 901  VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 960
            VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS
Sbjct: 901  VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 960

Query: 961  PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 1020
            PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT
Sbjct: 961  PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 1020

Query: 1021 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1080
            GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL
Sbjct: 1021 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1080

Query: 1081 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1140
            RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP
Sbjct: 1081 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1140

Query: 1141 WYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQEL 1200
            WYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQEL
Sbjct: 1141 WYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQEL 1200

Query: 1201 SIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDI 1260
            SIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDI
Sbjct: 1201 SIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDI 1260

Query: 1261 SQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVE 1320
            SQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVE
Sbjct: 1261 SQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVE 1320

Query: 1321 VGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQ 1380
            VGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQ
Sbjct: 1321 VGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQ 1380

Query: 1381 GIPEIDKPSQEFPEEIDLQAQEVPEEIN 1408
            GIPEIDKPSQEFPEEIDLQAQEVPEEIN
Sbjct: 1381 GIPEIDKPSQEFPEEIDLQAQEVPEEIN 1408


>gi|66932992 histidine acid phosphatase domain containing 2A isoform 2
            [Homo sapiens]
          Length = 1408

 Score = 2841 bits (7364), Expect = 0.0
 Identities = 1408/1408 (100%), Positives = 1408/1408 (100%)

Query: 1    MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 60
            MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC
Sbjct: 1    MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 60

Query: 61   AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 120
            AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK
Sbjct: 61   AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 120

Query: 121  AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 180
            AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG
Sbjct: 121  AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 180

Query: 181  EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 240
            EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR
Sbjct: 181  EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 240

Query: 241  KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 300
            KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM
Sbjct: 241  KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 300

Query: 301  EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 360
            EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE
Sbjct: 301  EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 360

Query: 361  LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 420
            LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA
Sbjct: 361  LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 420

Query: 421  LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 480
            LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY
Sbjct: 421  LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 480

Query: 481  GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 540
            GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR
Sbjct: 481  GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 540

Query: 541  AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 600
            AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL
Sbjct: 541  AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 600

Query: 601  TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 660
            TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS
Sbjct: 601  TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 660

Query: 661  LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 720
            LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE
Sbjct: 661  LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 720

Query: 721  RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 780
            RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR
Sbjct: 721  RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 780

Query: 781  EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 840
            EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH
Sbjct: 781  EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 840

Query: 841  VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 900
            VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH
Sbjct: 841  VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 900

Query: 901  VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 960
            VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS
Sbjct: 901  VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 960

Query: 961  PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 1020
            PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT
Sbjct: 961  PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 1020

Query: 1021 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1080
            GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL
Sbjct: 1021 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1080

Query: 1081 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1140
            RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP
Sbjct: 1081 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1140

Query: 1141 WYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQEL 1200
            WYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQEL
Sbjct: 1141 WYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQEL 1200

Query: 1201 SIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDI 1260
            SIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDI
Sbjct: 1201 SIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDI 1260

Query: 1261 SQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVE 1320
            SQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVE
Sbjct: 1261 SQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVE 1320

Query: 1321 VGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQ 1380
            VGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQ
Sbjct: 1321 VGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQ 1380

Query: 1381 GIPEIDKPSQEFPEEIDLQAQEVPEEIN 1408
            GIPEIDKPSQEFPEEIDLQAQEVPEEIN
Sbjct: 1381 GIPEIDKPSQEFPEEIDLQAQEVPEEIN 1408


>gi|195947359 histidine acid phosphatase domain containing 2A isoform
            5 [Homo sapiens]
          Length = 1433

 Score = 2823 bits (7317), Expect = 0.0
 Identities = 1408/1433 (98%), Positives = 1408/1433 (98%), Gaps = 25/1433 (1%)

Query: 1    MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 60
            MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC
Sbjct: 1    MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 60

Query: 61   AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 120
            AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK
Sbjct: 61   AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 120

Query: 121  AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 180
            AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG
Sbjct: 121  AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 180

Query: 181  EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 240
            EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR
Sbjct: 181  EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 240

Query: 241  KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 300
            KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM
Sbjct: 241  KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 300

Query: 301  EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 360
            EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE
Sbjct: 301  EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 360

Query: 361  LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 420
            LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA
Sbjct: 361  LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 420

Query: 421  LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 480
            LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY
Sbjct: 421  LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 480

Query: 481  GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 540
            GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR
Sbjct: 481  GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 540

Query: 541  AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 600
            AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL
Sbjct: 541  AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 600

Query: 601  TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 660
            TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS
Sbjct: 601  TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 660

Query: 661  LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 720
            LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE
Sbjct: 661  LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 720

Query: 721  RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 780
            RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR
Sbjct: 721  RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 780

Query: 781  EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPL----YSRGVLSPGRHVRTRLYFT 836
            EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPL    YSRGVLSPGRHVRTRLYFT
Sbjct: 781  EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLCYLRYSRGVLSPGRHVRTRLYFT 840

Query: 837  SESHVHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSE 896
            SESHVHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSE
Sbjct: 841  SESHVHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSE 900

Query: 897  ERFHVELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRA 956
            ERFHVELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRA
Sbjct: 901  ERFHVELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRA 960

Query: 957  LQTSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG 1016
            LQTSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG
Sbjct: 961  LQTSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG 1020

Query: 1017 SQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRD------------------- 1057
            SQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRD                   
Sbjct: 1021 SQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDELLFVPAVKRFSVSFAKHP 1080

Query: 1058 --GFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQAS 1115
              GFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQAS
Sbjct: 1081 TNGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQAS 1140

Query: 1116 DNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSL 1175
            DNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSL
Sbjct: 1141 DNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSL 1200

Query: 1176 NSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQE 1235
            NSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQE
Sbjct: 1201 NSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQE 1260

Query: 1236 VPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKV 1295
            VPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKV
Sbjct: 1261 VPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKV 1320

Query: 1296 SEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVI 1355
            SEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVI
Sbjct: 1321 SEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVI 1380

Query: 1356 QPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQAQEVPEEIN 1408
            QPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQAQEVPEEIN
Sbjct: 1381 QPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQAQEVPEEIN 1433


>gi|66932994 histidine acid phosphatase domain containing 2A isoform 4
            [Homo sapiens]
          Length = 1194

 Score = 1724 bits (4466), Expect = 0.0
 Identities = 938/1274 (73%), Positives = 993/1274 (77%), Gaps = 98/1274 (7%)

Query: 1    MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 60
            MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC
Sbjct: 1    MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 60

Query: 61   AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 120
            AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK
Sbjct: 61   AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 120

Query: 121  AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 180
            AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG
Sbjct: 121  AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 180

Query: 181  EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 240
            EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR
Sbjct: 181  EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 240

Query: 241  KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 300
            KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM
Sbjct: 241  KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 300

Query: 301  EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 360
            EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE
Sbjct: 301  EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 360

Query: 361  LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 420
            LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA
Sbjct: 361  LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 420

Query: 421  LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 480
            LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY
Sbjct: 421  LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 480

Query: 481  GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 540
            GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR
Sbjct: 481  GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 540

Query: 541  AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 600
            AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL
Sbjct: 541  AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 600

Query: 601  TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 660
            TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS
Sbjct: 601  TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 660

Query: 661  LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 720
            LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE
Sbjct: 661  LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 720

Query: 721  RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 780
            RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR
Sbjct: 721  RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 780

Query: 781  EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 840
            EEKLEIAVGFCLPLLRKILLDLQRTHEDE        YSRGVLSPGRHVRTRLYFTSESH
Sbjct: 781  EEKLEIAVGFCLPLLRKILLDLQRTHEDE--------YSRGVLSPGRHVRTRLYFTSESH 832

Query: 841  VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 900
            VHSLLSVFRYGGLLDETQDA   RAL       E   + +          + PL   R  
Sbjct: 833  VHSLLSVFRYGGLLDETQDA--DRALQTSPQPPEGPGLPR----------RSPLIRNR-- 878

Query: 901  VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 960
                   G   V  E S+    G+R  SS     +  Q  + + C G  S        ++
Sbjct: 879  -----KAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSA 933

Query: 961  PQPPE-----GPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGL 1015
            P   +     G  LP  S   R+      E+L   +  R   + +  +  P         
Sbjct: 934  PNLQDYARSHGKKLPPASLKHRD------ELLFVPAVKR---FSVSFAKHP--------- 975

Query: 1016 GSQCTGLFSTTVLGGSSSAPNLQDYARSHG----KKLPP--ASLKHRDGFEGCSMVPTIY 1069
                     T    G S  P +      H     +++PP   S  + +  + C  VP I 
Sbjct: 976  ---------TNGFEGCSMVPTIYPLETLHNALSLRQVPPMETSQPYEEVSQPCQEVPDI- 1025

Query: 1070 PLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPP 1129
                   +   + +SE LS+ CQ+  D   Q      +  H+ Q   +   P        
Sbjct: 1026 -------SQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPHISQP---CQKSS 1075

Query: 1130 LQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLG-L 1188
               Q+ SE+        S  VS   P    +V+            +   V + H G+G L
Sbjct: 1076 QLCQKVSEEVCQLCLENSEEVSQ--PCQGVSVE------------VGKLVHKFHVGVGSL 1121

Query: 1189 LQET---PGSGAQELSIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQD 1245
            +QET    GS A+E+     +E+ +P Q   V     +Q    ++   Q +P+I +P Q+
Sbjct: 1122 VQETLVEVGSPAEEI----PEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQE 1177

Query: 1246 ISEALSQPCQKVPD 1259
              E +    Q+VP+
Sbjct: 1178 FPEEIDLQAQEVPE 1191



 Score =  395 bits (1016), Expect = e-109
 Identities = 193/193 (100%), Positives = 193/193 (100%)

Query: 1216 QVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTC 1275
            QVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTC
Sbjct: 1002 QVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTC 1061

Query: 1276 QEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSL 1335
            QEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSL
Sbjct: 1062 QEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSL 1121

Query: 1336 VQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEE 1395
            VQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEE
Sbjct: 1122 VQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEE 1181

Query: 1396 IDLQAQEVPEEIN 1408
            IDLQAQEVPEEIN
Sbjct: 1182 IDLQAQEVPEEIN 1194


>gi|41281583 Histidine acid phosphatase domain containing 1 [Homo
            sapiens]
          Length = 1222

 Score = 1574 bits (4076), Expect = 0.0
 Identities = 819/1199 (68%), Positives = 933/1199 (77%), Gaps = 65/1199 (5%)

Query: 11   STTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKP 70
            S    FF+G  D  +           +D +  ++EED+ PPE QI+VGIC+M KKSKSKP
Sbjct: 2    SEAPRFFVGPEDTEINPGNYRHFFHHADED--DEEEDDSPPERQIVVGICSMAKKSKSKP 59

Query: 71   MTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDKAVAYSKLRNP 130
            M +ILER+  F Y+TVV+  E+VILNEPVENWP C CLISFHSKGFPLDKAVAY+KLRNP
Sbjct: 60   MKEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNP 119

Query: 131  FLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEGEDQVEVNGAV 190
            F+INDL MQY IQDRREVY ILQ EGI LPRYA+LNRDP  P+ECNLIEGED VEVNG V
Sbjct: 120  FVINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEV 179

Query: 191  FPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEF 250
            F KPFVEKPVSAEDHNVYIYYP+SAGGGSQRLFRKIGSRSSVYSPES+VRKTGSYIYEEF
Sbjct: 180  FQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEF 239

Query: 251  MPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAMEKLVARKVCV 310
            MPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKE+RYPV+L A EKL+A KVC+
Sbjct: 240  MPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCL 299

Query: 311  AFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWS 370
            AFKQTVCGFDLLRANG S+VCDVNGFSFVKNSMKYYDDCAKILGN +MRELAPQF IPWS
Sbjct: 300  AFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWS 359

Query: 371  IPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFALFEKHGGYKT 430
            IP EAEDIPIVPTTSGTMMELRCVIA+IRHGDRTPKQKMKMEV+H +FF LFEK  GYK+
Sbjct: 360  IPLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKS 419

Query: 431  GKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMYGHFSGINRKV 490
            GKLKLK+P+QLQEVLDI R LL EL +    EIEE   KLEQLK+VLEMYGHFSGINRKV
Sbjct: 420  GKLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKV 479

Query: 491  QLTYYPHGV-KASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGG 549
            QLTY PHG  K S+E +D +RE   PSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGG
Sbjct: 480  QLTYLPHGCPKTSSEEEDSRRE--EPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGG 537

Query: 550  QGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVK 609
            QGDYAGFPGCGLLRLHST+RHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVK
Sbjct: 538  QGDYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVK 597

Query: 610  SANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTSLLNSMTIIQ 669
            SANMNGLLDSD DSLSSCQ RVKARLH ILQ+D  F  EDY++L P+ S SL+ SM +I+
Sbjct: 598  SANMNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIK 657

Query: 670  NPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLERDFRQKSGR 729
            NPVK CD+V++LI++LT QIR RM+DP+S D+QLYHSETLELML+RWSKLE+DF+ K+GR
Sbjct: 658  NPVKTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGR 717

Query: 730  YDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKLEIAVG 789
            YDISKIPDIYDC+KYDVQHNGSL L+ T EL RLSKALAD+VIPQEYGI++ EKLEIA G
Sbjct: 718  YDISKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKG 777

Query: 790  FCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFR 849
            +C PL+RKI  DLQRT +D++VNKLHP+YSRGVLSP RHVRTRLYFTSESHVHSLLS+ R
Sbjct: 778  YCTPLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILR 837

Query: 850  YGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFHVELHFSPGV 909
            YG L +E++D QW+RA+DYL+ ++ELNYMTQIVIMLYED  +D  SEERFHVELHFSPG 
Sbjct: 838  YGALCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGA 897

Query: 910  KGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRA-LQTSPQPPEGPG 968
            KG EE+ + P+G G+RPAS ENE  +  +   ++       DE DRA +   P   E   
Sbjct: 898  KGCEEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIH 957

Query: 969  LPRRSPLIRNRKAGSMEVLSETSSSRPGG------------------------------- 997
            + R+SPL R+RK  + +  S  S S P G                               
Sbjct: 958  IHRKSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSP 1017

Query: 998  -YRLFSSS-------------------RPPTEMKQS-GLGSQCTGLFSTTVLGGSSSAPN 1036
                F+SS                   R   E KQ+  +GS C GLFST+VLGGSSSAPN
Sbjct: 1018 KSLAFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPN 1077

Query: 1037 LQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTD 1096
            LQDYAR+H KKL  +     DGFE  SMVP+I PLETLHNALSL+QV EFL+ +    +D
Sbjct: 1078 LQDYARTHRKKLTSSGC--IDGFELYSMVPSICPLETLHNALSLKQVDEFLASIASPSSD 1135

Query: 1097 AQAQASAALFDSMHSS-----QASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTV 1150
               + +     ++ SS     + S N ++P + L +PP  L+         +SGPSS V
Sbjct: 1136 VPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKSTKASSKPATSGPSSAV 1194


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 78/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)

Query: 891  QDPLSEERFHVELHFSPGVKGVEEEGSAPAG--------CGFRPASSENEEMKTNQGSME 942
            +DPLS      +    PG++   + G +P+            R  S E E +   +G   
Sbjct: 61   EDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTT 120

Query: 943  NLCPGKASDEPDRALQTSPQPPEGPGLPRRSPLI------RNRKAGSMEVLSETSSSRPG 996
            +LC G  +++P     +SP           S +       +  +A S + L+     RP 
Sbjct: 121  SLC-GSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPR 179

Query: 997  -GYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASL-K 1054
             G R  SS R P+ + +S +G    G       GG  SA   Q +AR  G+     SL +
Sbjct: 180  EGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAG--QHWARLRGES--GLSLER 235

Query: 1055 HRDGF-EGCSMVPTIYPLETLH----------NALSLRQVSEFLS--RVCQRHT----DA 1097
            HR    +  SM P   P  T             A S R++    S  R+ QR T      
Sbjct: 236  HRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASST 295

Query: 1098 QAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPW---YSSGPSSTVSSAG 1154
            Q + S A      +S+AS      PR   S   +   R+    W    +S PS +     
Sbjct: 296  QQEISRASSTQQETSRASSTQEDTPRA--SSTQEDTPRASSTQWNTPRASSPSRSTQLDN 353

Query: 1155 PSSPTTVDGNSQFGF 1169
            P + +T   N Q  F
Sbjct: 354  PRTSSTQQDNPQTSF 368


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 78/366 (21%), Positives = 130/366 (35%), Gaps = 60/366 (16%)

Query: 915  EGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTSPQPPEGPGLPRRSP 974
            E + PA    RP SS  +E    Q    +L  G+  + P    + +P+P EG   PR+ P
Sbjct: 310  ESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDP 369

Query: 975  LIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSA 1034
                     + ++      +P      SS  PP++  +                GG+   
Sbjct: 370  -------PWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQ------------VENGGTEEV 410

Query: 1035 PNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTI-------YPLETLHNALSLRQVSEFL 1087
                  A    K   P   +  D  E     P++       +P  T  +      ++   
Sbjct: 411  AQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTS 470

Query: 1088 SRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRS----------- 1136
            S   ++    +A +++ L  ++H+S+ S +   PP    SP L ++  S           
Sbjct: 471  SPKTKKRPAPRAPSASPL--ALHASRLSHS--EPPSATPSPALSVESLSSESASQTAGAE 526

Query: 1137 --EKPPWYSSGPSSTVSSAG-PSSPTTVDGNSQFGFSDQ---------PSLNSHVAEEHQ 1184
              E P    S     V + G P +P ++  NS    S +         P  +  +A   +
Sbjct: 527  LLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTR 586

Query: 1185 G-LGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPC 1243
            G  G     P SGA    +     L   ++SP VP   +S P  +V   C+E P   +P 
Sbjct: 587  GSSGPQPAKPCSGATPTPL-----LLVGDRSP-VPSPGSSSPQLQVKSSCKENPFNRKPS 640

Query: 1244 QDISEA 1249
               S A
Sbjct: 641  PAASPA 646


>gi|149999615 variable charge, X-linked 3B [Homo sapiens]
          Length = 216

 Score = 41.2 bits (95), Expect = 0.007
 Identities = 45/155 (29%), Positives = 70/155 (45%), Gaps = 16/155 (10%)

Query: 1153 AGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGS-GAQELSIEGEQELFEP 1211
            A  ++P    G +  G SDQPS       +H+   L  E P S G Q   +  E EL EP
Sbjct: 60   AAVTAPEAESGPAAPGPSDQPSQE---LPQHE---LPPEEPVSEGTQHDPLSQESELEEP 113

Query: 1212 -NQSPQV--PPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENH 1268
             +Q  +V  P  + SQ  E +SQ  +    +SQ  Q + E LSQ  +    +SQ+ Q   
Sbjct: 114  LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQ-VEEPLSQESEVEEPLSQESQVEE 172

Query: 1269 DNGNHTCQEVP-----HISQPCQKSSQLCQKVSEE 1298
                 +  E P      + +P  + S++ + +S+E
Sbjct: 173  PLSQESEMEEPLSQESQVEEPLSQESEMEEPLSQE 207


>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
          Length = 860

 Score = 40.0 bits (92), Expect = 0.016
 Identities = 80/354 (22%), Positives = 126/354 (35%), Gaps = 40/354 (11%)

Query: 1004 SRPPTEMKQSGLGSQCTGLF---STTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFE 1060
            +RP +E ++ G  S    L    S  +      A  +    R  G+  P       D   
Sbjct: 323  ARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSD-IS 381

Query: 1061 GCSMVPTIYPLETLHNALSLRQVSE-FLSRVCQRHTDAQAQASAALFDSMHSSQASDNPF 1119
                VP+   LE    A+ +   +E FL         AQA ++++  +S HS+    +P 
Sbjct: 382  TLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPD 441

Query: 1120 SPPR---------TLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSQFGFS 1170
            S  R         T H      ++ S KP     G    V S   S+  T     +  F+
Sbjct: 442  SEQRQSVEASGHHTHHQSDNNNEKLSPKP-----GTGEPVLSLHYSTEGTTTSTIKLNFT 496

Query: 1171 DQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVP--PMETSQPYE- 1227
            D+ S    +A   +G+G               EG++E F P  S Q P    ET  P E 
Sbjct: 497  DEWS---SIASSSRGIG----------SHCKSEGQEESFVPQSSVQPPEGDSETKAPEES 543

Query: 1228 -EVSQPCQEVPDISQPCQD-ISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPHISQPC 1285
             E     QE      P ++ I+   S      P  S   + N  N + +C  VP  S   
Sbjct: 544  SEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSC-GVPEESASS 602

Query: 1286 QKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQET 1339
            +K+ +   + S++       N    +   Q  +   G   H+      S +Q+T
Sbjct: 603  EKAKE--PETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDT 654


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 40.0 bits (92), Expect = 0.016
 Identities = 71/330 (21%), Positives = 114/330 (34%), Gaps = 47/330 (14%)

Query: 927  ASSENEEMKTNQGSMENLCPGKASD-----EPDRALQTSPQPPEGPGLPRRSPLIRNRKA 981
            AS  +EE +T+  S  +      S      E   +  +SP        P  S      + 
Sbjct: 1933 ASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 1992

Query: 982  GSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYA 1041
             +    S +S    G   L + S     + +S      +G   TT L GS++ P L + +
Sbjct: 1993 STA---SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 2049

Query: 1042 RS-HGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQ 1100
             + H     PA+              T+ P  T  + +S    +   SR    HT A   
Sbjct: 2050 TTFHSSPRSPAT--------------TLSPASTTSSGVSEESTTSH-SRPGSTHTTAFPD 2094

Query: 1101 ASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTT 1160
            ++     S HS+ +  +P S   TL          S++     S P ST ++  P S T 
Sbjct: 2095 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTA 2154

Query: 1161 VD-GNSQFGFSDQP-----------SLNSHVAEE----HQGLGLLQET--PGSGAQELSI 1202
            +  G     F   P           + +S + E     H   G  + T  P S      +
Sbjct: 2155 LSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP-GL 2213

Query: 1203 EGEQELFEPN----QSPQVPPMETSQPYEE 1228
            +GE   F+ +     +   PP   + P EE
Sbjct: 2214 QGESTAFQTHPASTHTTPSPPSTATAPVEE 2243



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 58/264 (21%), Positives = 93/264 (35%), Gaps = 39/264 (14%)

Query: 988  SETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARS-HGK 1046
            S +S    G   L + S     + +S      +G   TT L GS++ P L + + + H  
Sbjct: 3553 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 3612

Query: 1047 KLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALF 1106
               PA+              T+ P  T  + +S    +   SR    HT A   ++    
Sbjct: 3613 PRSPAT--------------TLSPASTTSSGVSEESTTSH-SRPGSTHTTAFPDSTTTPG 3657

Query: 1107 DSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVD-GNS 1165
             S HS+ +  +P S   TL          S++     S   ST ++  P S T +  G  
Sbjct: 3658 LSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQE 3717

Query: 1166 QFGFSDQP-----------SLNSHVAEE----HQGLGLLQET--PGSGAQELSIEGEQEL 1208
               F   P           + +S + E     H   G  + T  P S      ++GE   
Sbjct: 3718 STTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP-GLQGESTA 3776

Query: 1209 FEPN----QSPQVPPMETSQPYEE 1228
            F+ +     +   PP   + P EE
Sbjct: 3777 FQTHPASTHTTPSPPSTATAPVEE 3800



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 75/313 (23%), Positives = 113/313 (36%), Gaps = 27/313 (8%)

Query: 903  LHFSPGVKGVE--EEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 960
            +H SPG  G       SA +     P +S      T   ++          E      +S
Sbjct: 4278 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 4337

Query: 961  PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLF---SSSRPPTEMKQSGLGS 1017
            P+ P+       SP        S E  S TS SRPG        SS+  P   ++S    
Sbjct: 4338 PRSPD----TTLSPASTTSSGVSEE--STTSHSRPGSMHTTAFPSSTTMPGVSQESTASH 4391

Query: 1018 QCTGLFSTTVLGGSSSA----PNLQDYARSHGKK---LPPASLKHRDGFEGCSMV--PTI 1068
               G   TT+  GS++A    P    +  S G     L P +       E  + V   T 
Sbjct: 4392 SSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTG 4451

Query: 1069 YPLETLHNALSLRQVSE---FLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTL 1125
             P  TL  A S  +  E   F S    + T      + + F  + S+ +  +P S P T 
Sbjct: 4452 SPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL-STTSHGSPSSTPTTH 4510

Query: 1126 HSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTT---VDGNSQFGFSDQPSLNSHVAEE 1182
             S       RSE+     S P +T ++  P+  TT   V+ ++ +  S   +   H  E 
Sbjct: 4511 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 4570

Query: 1183 HQGLGLLQETPGS 1195
            +   G  +E+  S
Sbjct: 4571 NTTSGRGEESTTS 4583



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 53/239 (22%), Positives = 86/239 (35%), Gaps = 24/239 (10%)

Query: 988  SETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARS-HGK 1046
            S +S    G   L + S     + +S      +G   TT L GS++ P L + + + H  
Sbjct: 913  SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSS 972

Query: 1047 KLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALF 1106
               PA+              T+ P  T  + +S    +   SR    HT A   ++    
Sbjct: 973  PRSPAT--------------TLSPASTTSSGVSEESTTS-RSRPGSTHTTAFPDSTTTPG 1017

Query: 1107 DSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSQ 1166
             S HS+ +  +P S   TL          S++     S   ST ++  P S T +     
Sbjct: 1018 LSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTAL----S 1073

Query: 1167 FGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPMETSQP 1225
            FG  +  + +S+    H  L     T  SG  E S         P  +  + P  ++ P
Sbjct: 1074 FG-QESTTFHSNPGSTHTTL-FPDSTTSSGIVEASTRVHSSTGSPRTT--LSPASSTSP 1128



 Score = 35.4 bits (80), Expect = 0.39
 Identities = 67/297 (22%), Positives = 104/297 (35%), Gaps = 28/297 (9%)

Query: 919  PAGCGFRPASSENEEMKTNQGSMENLC-PGKAS----DEPDRALQTSPQPPEGPGLPRRS 973
            PAG        ++     + GSME    PG  +     E      +SP+ P+   LP   
Sbjct: 596  PAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPA-- 653

Query: 974  PLIRNRKAGSMEVLSETSSSRPGGYRLFS---SSRPPTEMKQSGLGSQCTGLFSTTVLGG 1030
                +  +  +   S TS SRPG     +   S+  P   ++S       G   TT+  G
Sbjct: 654  ----SMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPG 709

Query: 1031 SSSAPNL-QDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLE--------TLHNALSLR 1081
            S++A +L  +Y   H +     +    D      ++    P+         TL  A S  
Sbjct: 710  STTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTT 769

Query: 1082 QVSE---FLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEK 1138
            +  E   F S    + T      + + F    S+ +  +P S P T  S         E+
Sbjct: 770  RQGESTTFHSWPSSKDTRPAPPTTTSAFVEP-STTSHGSPSSIPTTHISARSTTSGLVEE 828

Query: 1139 PPWYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGS 1195
               Y S P ST +   P S TT  G  +   +   S    ++        L E P S
Sbjct: 829  STTYHSSPGSTQTMHFPESDTT-SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 884



 Score = 35.4 bits (80), Expect = 0.39
 Identities = 73/310 (23%), Positives = 111/310 (35%), Gaps = 27/310 (8%)

Query: 903  LHFSPGVKGVE--EEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 960
            +H SPG  G       SA +     P +S      T   ++          E      +S
Sbjct: 1638 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 1697

Query: 961  PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFS---SSRPPTEMKQSGLGS 1017
            P+ P+       SP        S E  S TS SRPG     +   S+  P   ++S    
Sbjct: 1698 PRSPD----TTLSPASTTSSGVSEE--STTSHSRPGSTHTTAFPGSTTMPGVSQESTASH 1751

Query: 1018 QCTGLFSTTVLGGSSSA----PNLQDYARSHGKK---LPPASLKHRDGFEGCSMV--PTI 1068
               G   TT+  GS++A    P    +  S G     L P +       E  + V   T 
Sbjct: 1752 SSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTG 1811

Query: 1069 YPLETLHNALSLRQVSE---FLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTL 1125
             P  TL  A S  +  E   F S    + T      + + F  + S+ +  +P S P T 
Sbjct: 1812 SPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVEL-STTSHGSPSSTPTTH 1870

Query: 1126 HSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTT---VDGNSQFGFSDQPSLNSHVAEE 1182
             S       RSE+     S P +T ++  P+  TT   V+ ++ +  S   +   H  E 
Sbjct: 1871 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPES 1930

Query: 1183 HQGLGLLQET 1192
                G  +E+
Sbjct: 1931 STASGRSEES 1940



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 60/250 (24%), Positives = 90/250 (36%), Gaps = 41/250 (16%)

Query: 959  TSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYR----LFSSSRPPTEMKQSG 1014
            T+P PP     P       +R  GS       +SS   G+     +F SS   +    S 
Sbjct: 2229 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2288

Query: 1015 LGSQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETL 1074
              S  +G   +T    S  +P   +     G    P   +    F      PT       
Sbjct: 2289 AHSTTSGRGESTT---SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT------ 2339

Query: 1075 HNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQ 1134
                +L   S     V +  T +++Q       S HS+ +       P +  +P L    
Sbjct: 2340 ----TLSPASMTSLGVGEESTTSRSQPG-----STHSTVS-------PASTTTPGLS--- 2380

Query: 1135 RSEKPPWYSSGPSSTVSSAGPSSPTT-VDGNSQFGFSDQPSLNSHV---AEEHQGLGLLQ 1190
              E    YSS P ST ++  P +PTT V G     F  +P+ ++H     E+    GL +
Sbjct: 2381 -EESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPA-STHTTLFTEDSTTSGLTE 2438

Query: 1191 ET---PGSGA 1197
            E+   PGS A
Sbjct: 2439 ESTAFPGSPA 2448



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 60/272 (22%), Positives = 96/272 (35%), Gaps = 47/272 (17%)

Query: 987  LSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT------GLFSTTVLGGSSSAPNLQDY 1040
            L E S++ P       ++  P     SGL  + T          TT L GS + P+L + 
Sbjct: 2463 LGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 2522

Query: 1041 ARSH--GKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQ 1098
            + +     + P A+L                P  T  + +S  + S   S+    HT A 
Sbjct: 2523 STTFYTSPRSPDATLS---------------PATTTSSGVS-EESSTSHSQPGSTHTTAF 2566

Query: 1099 AQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSP 1158
              ++     S HS+ +  +P S   TL          S++     S P ST ++  P S 
Sbjct: 2567 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGST 2626

Query: 1159 TTVD-GNSQFGFSDQP-----------SLNSHVAEE----HQGLGLLQET--PGSGAQEL 1200
            T +  G     F   P           + +S + E     H   G  + T  P S     
Sbjct: 2627 TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP- 2685

Query: 1201 SIEGEQELFEPN----QSPQVPPMETSQPYEE 1228
             ++GE   F+ +     +   PP   + P EE
Sbjct: 2686 GLQGESTTFQTHPASTHTTPSPPSTATAPVEE 2717



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 73/313 (23%), Positives = 112/313 (35%), Gaps = 27/313 (8%)

Query: 903  LHFSPGVKGVE--EEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 960
            +H SPG  G       SA +     P +S      T   ++          E      +S
Sbjct: 3195 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 3254

Query: 961  PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFS---SSRPPTEMKQSGLGS 1017
            P+ P+       SP        S E  S TS SRPG     +   S+  P   ++S    
Sbjct: 3255 PRSPD----TTLSPASTTSSGVSEE--STTSHSRPGSTHTTAFPGSTTMPGVSQESTASH 3308

Query: 1018 QCTGLFSTTVLGGSSSAPNLQDYAR-------SHGKKLPPASLKHRDGFEGCSMV--PTI 1068
               G   TT+  GS++A +L   +        S    L P +       E  + V   T 
Sbjct: 3309 SSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTG 3368

Query: 1069 YPLETLHNALSLRQVSE---FLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTL 1125
             P  TL  A S  +  E   F S    + T      + + F  + S+ +  +P S P T 
Sbjct: 3369 SPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL-STTSHGSPSSTPTTH 3427

Query: 1126 HSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTT---VDGNSQFGFSDQPSLNSHVAEE 1182
             S       RSE+     S P +T ++  P+  TT   V+ ++ +  S   +   H  E 
Sbjct: 3428 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 3487

Query: 1183 HQGLGLLQETPGS 1195
                G  +E+  S
Sbjct: 3488 DTTSGRGEESTTS 3500



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 47/210 (22%), Positives = 71/210 (33%), Gaps = 18/210 (8%)

Query: 988  SETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYA---RSH 1044
            S +S    G   L + S     + +S      +G   TT L GS++ P L + +    S 
Sbjct: 4636 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 4695

Query: 1045 GKKLPPASLKHRDGFEGCSMVPTIY---PLETLHNALSLRQVSEFLSRVCQRHTDAQAQA 1101
                P           G S   T     P+ T       R  +  L      +  +    
Sbjct: 4696 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 4755

Query: 1102 SAALFD-----SMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPS 1156
                F      S  S ++  +  S   T+ SPP       E+P  Y S P S  ++  P 
Sbjct: 4756 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPE 4815

Query: 1157 SPTTVDGNSQFGFSDQPSLNSHVAEEHQGL 1186
            S TT  G S      + S  SH + +  G+
Sbjct: 4816 SSTT-SGRS------EESTASHSSPDTNGI 4838



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 60/250 (24%), Positives = 89/250 (35%), Gaps = 41/250 (16%)

Query: 959  TSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYR----LFSSSRPPTEMKQSG 1014
            T+P PP     P       +R  GS       +SS   G+     +F SS   +    S 
Sbjct: 2703 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2762

Query: 1015 LGSQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETL 1074
              S  +G   +T    S  +P   +     G    P   +    F      PT       
Sbjct: 2763 AHSTTSGRGESTT---SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT------ 2813

Query: 1075 HNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQ 1134
                +L   S     V +  T +++Q       S HS+ +       P +  +P L    
Sbjct: 2814 ----TLSPASMTSLGVGEESTTSRSQPG-----STHSTVS-------PASTTTPGLS--- 2854

Query: 1135 RSEKPPWYSSGPSSTVSSAGPSSPTT-VDGNSQFGFSDQPSLNSHV---AEEHQGLGLLQ 1190
              E    YSS P ST ++  P S TT V G     F  +P+ ++H     E+    GL +
Sbjct: 2855 -EESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPA-STHTTLFTEDSTTSGLTE 2912

Query: 1191 ET---PGSGA 1197
            E+   PGS A
Sbjct: 2913 ESTAFPGSPA 2922



 Score = 31.6 bits (70), Expect = 5.6
 Identities = 58/218 (26%), Positives = 79/218 (36%), Gaps = 34/218 (15%)

Query: 952  EPDRALQTSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRL--FSSSRPPTE 1009
            E      TSP+ P+       SP        S E  S TS S+PG      F  S   ++
Sbjct: 1438 EKSTTFYTSPRSPDAT----LSPATTTSSGVSEE--SSTSHSQPGSTHTTAFPDSTTTSD 1491

Query: 1010 MKQSGLGSQCT-GLFSTTVLGGSSSAPNL-QDYARSHGKKLPPASLKHRDGFEGCSMV-- 1065
            + Q    S  + G    T+  GS++A +L Q     H       +    D      +V  
Sbjct: 1492 LSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA 1551

Query: 1066 --PTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPR 1123
              PT     +LH  L+               T A  Q  +  F S  SS  SD   SPP 
Sbjct: 1552 STPTHSSTGSLHTTLTPAS-----------STSAGLQEESTTFQSWPSS--SDTTPSPPG 1598

Query: 1124 TLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTV 1161
            T  +P        E    Y S PSST ++   +S TT+
Sbjct: 1599 TTAAPV-------EVSTTYHSRPSSTPTTHFSASSTTL 1629



 Score = 30.8 bits (68), Expect = 9.6
 Identities = 58/218 (26%), Positives = 78/218 (35%), Gaps = 34/218 (15%)

Query: 952  EPDRALQTSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRL--FSSSRPPTE 1009
            E      TSP+ P+       SP        S E  S TS S+PG      F  S   + 
Sbjct: 2995 EKSTTFYTSPRSPDAT----LSPATTTSSGVSEE--SSTSHSQPGSTHTTAFPDSTTTSG 3048

Query: 1010 MKQSGLGSQCT-GLFSTTVLGGSSSAPNL-QDYARSHGKKLPPASLKHRDGFEGCSMV-- 1065
            + Q    S  + G    T+  GS++A +L Q     H       +    D      +V  
Sbjct: 3049 LSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA 3108

Query: 1066 --PTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPR 1123
              PT     +LH  L+               T A  Q  +  F S  SS  SD   SPP 
Sbjct: 3109 STPTHSSTGSLHTTLTPAS-----------STSAGLQEESTTFQSWPSS--SDTTPSPPG 3155

Query: 1124 TLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTV 1161
            T  +P        E    Y S PSST ++   +S TT+
Sbjct: 3156 TTAAPV-------EVSTTYHSRPSSTPTTHFSASSTTL 3186


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 39.3 bits (90), Expect = 0.027
 Identities = 43/178 (24%), Positives = 75/178 (42%), Gaps = 23/178 (12%)

Query: 1145 GPSSTVSSAGPSSPTTVDGNSQFGFSDQ-PSLNSHVAEEHQGLGLLQETPGSGAQELSIE 1203
            GP +    +G S     +   +   S Q P++++ V     G   + E    G +EL ++
Sbjct: 38   GPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPV-----GASEIAEETRPGQRELQLQ 92

Query: 1204 GEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKV------ 1257
              ++  EP Q PQ   ++  QP+ E+ Q         QP QD  + LSQ  Q+       
Sbjct: 93   QLEQQPEPQQQPQHEQLQQPQPHLELQQ---------QPQQDGQQQLSQLQQEKHQSVHH 143

Query: 1258 PDISQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQ 1315
             ++  + Q  H       Q+V    +  Q+  QL  + ++E  Q  L+  E++ Q  Q
Sbjct: 144  QELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQE--QQVLQQQEQLQQQVQ 199


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 39.3 bits (90), Expect = 0.027
 Identities = 59/264 (22%), Positives = 94/264 (35%), Gaps = 39/264 (14%)

Query: 988  SETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARS-HGK 1046
            S +S    G   L + S     + +S      +G   TT L GS++ P L + + + H  
Sbjct: 72   SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 131

Query: 1047 KLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALF 1106
               PA+              T+ P  T  + +S    +   SR    HT A   ++    
Sbjct: 132  PRSPAT--------------TLSPASTTSSGVSEESTTSH-SRPGSTHTTAFPDSTTTPG 176

Query: 1107 DSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVD-GNS 1165
             S HS+ +  +P S   TL          S++     S P ST ++  P S T +  G  
Sbjct: 177  LSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE 236

Query: 1166 QFGFSDQP-----------SLNSHVAEE----HQGLGLLQET--PGSGAQELSIEGEQEL 1208
               F   P           + +S + E     H   G  + T  P S      ++GE   
Sbjct: 237  STTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP-GLQGESTA 295

Query: 1209 FEPN----QSPQVPPMETSQPYEE 1228
            F+ +     +   PP   + P EE
Sbjct: 296  FQTHPASTHTTPSPPSTATAPVEE 319



 Score = 30.8 bits (68), Expect = 9.6
 Identities = 47/202 (23%), Positives = 68/202 (33%), Gaps = 22/202 (10%)

Query: 959  TSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQ 1018
            T+P PP     P       +R  GS       +SS   G+   S             G+ 
Sbjct: 305  TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH---SEKSTIFHSSPDASGTT 361

Query: 1019 CTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNAL 1078
             +   STT      S+ +      +H    P ++        G S  PT     T H++ 
Sbjct: 362  PSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTT-----SGLSQEPT-----TSHSSQ 411

Query: 1079 SLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEK 1138
               + +   +      T A  + S     + HS      P S P T  S       RSE+
Sbjct: 412  GSTEATLDTTPSPPGTTAAPVEVST----TYHS-----RPSSTPTTHFSASSTTLGRSEE 462

Query: 1139 PPWYSSGPSSTVSSAGPSSPTT 1160
                 S P ST ++A P S TT
Sbjct: 463  STTVHSSPGSTETTALPGSTTT 484


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 39.3 bits (90), Expect = 0.027
 Identities = 79/357 (22%), Positives = 135/357 (37%), Gaps = 38/357 (10%)

Query: 928  SSENEEMKTNQGSMENLCPGKASDEPDRALQT-SPQPPEGPGLPRRSPLIRNRKAGSMEV 986
            + + +E K N+         K++D  ++ L   +P P   P  P  +             
Sbjct: 2705 TDKGKEDKENRDQSAQCTASKSNDSTEQNLSDGTPMPDSYPTTPSSTD------------ 2752

Query: 987  LSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARSHGK 1046
             + TS S+     L SS + PT      LG     L S    GGSS+   +       G 
Sbjct: 2753 -AATSESKETLGTLQSSQQQPTLPTPPALGEVPQELQSPAGEGGSSTQLLMPVEPEELGP 2811

Query: 1047 KLPPASLKHRDGFEGCSMVPTIYPL--ETLHNALSLRQVSEFLSRVCQRHTDAQAQASAA 1104
              P    +        S  PTI  L  E   ++ +L  VS   S++     D  + AS  
Sbjct: 2812 TRPSGEAETTQ--MELSPAPTITSLSPERAEDSDALTAVS---SQLEGSPMDTSSLASCT 2866

Query: 1105 LFDSMHSSQASDNPFSPPRTLHSPP-------LQLQQRSE------KPPWYSSGPSSTVS 1151
            L +++  + A+ +    PR   S P        ++Q RS+      +PP  SS P+S+ S
Sbjct: 2867 LEEAVGDTSAAGSS-EQPRAGSSTPGDAPPAVAEVQGRSDGSGESAQPPEDSSPPASSES 2925

Query: 1152 SAGPSSPTTVDGNSQFGFSDQ--PSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELF 1209
            S+   S   + G    G  ++  PS +S   +   G+ L +    S    L  +  +E+ 
Sbjct: 2926 SSTRDSAVAISGADSRGILEEPLPSTSSEEEDPLAGISLPEGVDPSFLAALPDDIRREVL 2985

Query: 1210 EPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQE 1266
            + NQ    PP  T+      +      P +++   +   AL    Q+     Q+ ++
Sbjct: 2986 Q-NQLGIRPPTRTAPSTNSSAPAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQ 3041


>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
            sapiens]
          Length = 1634

 Score = 39.3 bits (90), Expect = 0.027
 Identities = 75/337 (22%), Positives = 116/337 (34%), Gaps = 44/337 (13%)

Query: 1092 QRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVS 1151
            Q H + + Q    L D   SS   + P   P+ L   P  +QQ +   P  SS  S T+ 
Sbjct: 217  QFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLP 276

Query: 1152 SAGPSSPTTVDGNSQFGFSD--------QPSLNSHVAEEHQGLGLLQETPGSGAQELSIE 1203
            +   S     +  + +   +        + ++ S    E +     QETP    +E+   
Sbjct: 277  NHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEV--- 333

Query: 1204 GEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQ 1263
                  EP+ + Q  P+E   P  E      E     QP +   E  S P Q+  +   Q
Sbjct: 334  ------EPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQ--ETPGQ 385

Query: 1264 CQENHD-----NGNHTCQEV--PHIS-QPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQ 1315
              E+H+      G+H    +  P +S +P      +  + S EV    +           
Sbjct: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGS 445

Query: 1316 GVSVEVGKLVHKFHVGVGSLVQETLVEVGSPA----------EEIPEEVIQPYQEFSVEV 1365
            G  VE   + H    G   L+ E+  E G  A          E I  E   P Q+ +   
Sbjct: 446  GNDVEPPAIQH----GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501

Query: 1366 GRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQAQE 1402
                 E    +L  Q  P     + EFP  +  Q  E
Sbjct: 502  HPQTAEEGESSLTHQEAP---AQTPEFPNVVVAQPPE 535


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 38.9 bits (89), Expect = 0.035
 Identities = 50/199 (25%), Positives = 71/199 (35%), Gaps = 24/199 (12%)

Query: 963  PPEGPGLPRRSPL-IRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTG 1021
            P   PG     P+ I      +    + T SS PG     +++   T       GS  T 
Sbjct: 3903 PSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG--TTHTATVLTTTTTTVATGSMATP 3960

Query: 1022 LFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLR 1081
              ST   G + + P     A +HG+ LPP+S  H       S    I  L T H      
Sbjct: 3961 SSSTQTSGTTHTPPVPNTTATTHGRSLPPSS-PHTVRTAWTSATSGI--LGTTH------ 4011

Query: 1082 QVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPW 1141
                    + +  T      +A    + HS+ A  +P    RT  SPP          P 
Sbjct: 4012 --------ITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPP----SPGTTTPG 4059

Query: 1142 YSSGPSSTVSSAGPSSPTT 1160
            ++ G S T ++A PS   T
Sbjct: 4060 HTRGTSRTTATATPSKTRT 4078



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 49/199 (24%), Positives = 71/199 (35%), Gaps = 24/199 (12%)

Query: 963  PPEGPGLPRRSPL-IRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTG 1021
            P   PG     P+ I      +    + T SS PG     +++   T       GS  T 
Sbjct: 2756 PSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG--TTHTATVLTTTTTTVATGSMATP 2813

Query: 1022 LFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLR 1081
              ST   G + + P     A +HG+ LPP+S  H       S    I  L T H      
Sbjct: 2814 SSSTQTSGTTHTPPVPNTMATTHGRSLPPSS-PHTVRTAWTSATSGI--LGTTH------ 2864

Query: 1082 QVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPW 1141
                    + +  T      +A    + HS+ A  +P    RT  SPP          P 
Sbjct: 2865 --------ITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPP----SPGTTTPG 2912

Query: 1142 YSSGPSSTVSSAGPSSPTT 1160
            +++  S T ++A PS   T
Sbjct: 2913 HTTATSRTTATATPSKTRT 2931



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 50/203 (24%), Positives = 73/203 (35%), Gaps = 32/203 (15%)

Query: 963  PPEGPGLPRRSPL-IRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQS----GLGS 1017
            P   PG  R  P+ I      +    + T SS PG      ++  PT +  +      GS
Sbjct: 4405 PSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG------TTHTPTVLTTTTTTVATGS 4458

Query: 1018 QCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNA 1077
              T   ST   G + + P     A +HG+ L P+S  H       S   T   L T H  
Sbjct: 4459 MATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSS-PHTVRTAWTS--ATSGTLGTTH-- 4513

Query: 1078 LSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSE 1137
                        + +  T      +A    + HS+ A  +P    RT  SPP        
Sbjct: 4514 ------------ITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPP----SPGT 4557

Query: 1138 KPPWYSSGPSSTVSSAGPSSPTT 1160
              P +++  S T ++A PS   T
Sbjct: 4558 TTPGHTTATSRTTATATPSKTRT 4580



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 50/203 (24%), Positives = 72/203 (35%), Gaps = 32/203 (15%)

Query: 963  PPEGPGLPRRSPL-IRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQS----GLGS 1017
            P   PG  R  P+ I      +    + T SS PG      ++  PT +  +      GS
Sbjct: 3258 PSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPG------TTHTPTVLTTTTTTVATGS 3311

Query: 1018 QCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNA 1077
              T   ST   G + + P     A +HG+ L P+S  H       S   T   L T H  
Sbjct: 3312 MATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSS-PHTVRTAWTS--ATSGTLGTTH-- 3366

Query: 1078 LSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSE 1137
                        + +  T      +A    + HS+ A  +P    RT  SPP        
Sbjct: 3367 ------------ITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPP----SPGT 3410

Query: 1138 KPPWYSSGPSSTVSSAGPSSPTT 1160
              P ++   S T ++A PS   T
Sbjct: 3411 TTPGHTRATSRTTATATPSKTRT 3433


>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 1 [Homo sapiens]
          Length = 1635

 Score = 38.9 bits (89), Expect = 0.035
 Identities = 75/337 (22%), Positives = 116/337 (34%), Gaps = 44/337 (13%)

Query: 1092 QRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVS 1151
            Q H + + Q    L D   SS   + P   P+ L   P  +QQ +   P  SS  S T+ 
Sbjct: 217  QFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLP 276

Query: 1152 SAGPSSPTTVDGNSQFGFSD--------QPSLNSHVAEEHQGLGLLQETPGSGAQELSIE 1203
            +   S     +  + +   +        + ++ S    E +     QETP    +E+   
Sbjct: 277  NHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEV--- 333

Query: 1204 GEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQ 1263
                  EP+ + Q  P+E   P  E      E     QP +   E  S P Q+  +   Q
Sbjct: 334  ------EPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQ--ETPGQ 385

Query: 1264 CQENHD-----NGNHTCQEV--PHIS-QPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQ 1315
              E+H+      G+H    +  P +S +P      +  + S EV    +           
Sbjct: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGS 445

Query: 1316 GVSVEVGKLVHKFHVGVGSLVQETLVEVGSPA----------EEIPEEVIQPYQEFSVEV 1365
            G  VE   + H    G   L+ E+  E G  A          E I  E   P Q+ +   
Sbjct: 446  GNDVEPPAIQH----GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501

Query: 1366 GRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQAQE 1402
                 E    +L  Q  P     + EFP  +  Q  E
Sbjct: 502  HPQTAEEGESSLTHQEAP---AQTPEFPNVVVAQPPE 535


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 2 [Homo sapiens]
          Length = 1700

 Score = 38.9 bits (89), Expect = 0.035
 Identities = 75/337 (22%), Positives = 116/337 (34%), Gaps = 44/337 (13%)

Query: 1092 QRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVS 1151
            Q H + + Q    L D   SS   + P   P+ L   P  +QQ +   P  SS  S T+ 
Sbjct: 217  QFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLP 276

Query: 1152 SAGPSSPTTVDGNSQFGFSD--------QPSLNSHVAEEHQGLGLLQETPGSGAQELSIE 1203
            +   S     +  + +   +        + ++ S    E +     QETP    +E+   
Sbjct: 277  NHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEV--- 333

Query: 1204 GEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQ 1263
                  EP+ + Q  P+E   P  E      E     QP +   E  S P Q+  +   Q
Sbjct: 334  ------EPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQ--ETPGQ 385

Query: 1264 CQENHD-----NGNHTCQEV--PHIS-QPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQ 1315
              E+H+      G+H    +  P +S +P      +  + S EV    +           
Sbjct: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGS 445

Query: 1316 GVSVEVGKLVHKFHVGVGSLVQETLVEVGSPA----------EEIPEEVIQPYQEFSVEV 1365
            G  VE   + H    G   L+ E+  E G  A          E I  E   P Q+ +   
Sbjct: 446  GNDVEPPAIQH----GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501

Query: 1366 GRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQAQE 1402
                 E    +L  Q  P     + EFP  +  Q  E
Sbjct: 502  HPQTAEEGESSLTHQEAP---AQTPEFPNVVVAQPPE 535


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 38.9 bits (89), Expect = 0.035
 Identities = 69/318 (21%), Positives = 112/318 (35%), Gaps = 40/318 (12%)

Query: 958  QTSPQPPEGP-GL--PRRSPLIRNRKAGSM--------------EVLSETSSSRPG---- 996
            Q SPQPP+GP G+  P +  +++ +  G++               VLS    ++ G    
Sbjct: 3789 QLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLM 3848

Query: 997  GYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPAS-LKH 1055
            G+RL ++ +   + +    GS          L   S  P L        ++L     L+ 
Sbjct: 3849 GHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQ 3908

Query: 1056 RDGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSS--- 1112
            +   +           +     L  +Q  + L +  Q+    Q Q               
Sbjct: 3909 QQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQ 3968

Query: 1113 ---QASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSQFGF 1169
               Q      +  RTL SP  Q QQ+    P   + P    SS G   PT +    +   
Sbjct: 3969 QQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNT 4028

Query: 1170 SDQPSLNSHVAE---EHQG----LGLLQET----PGSGAQELSIEGEQELFEPNQSPQVP 1218
             D P+++S   E    HQG    +G   E+    PG     LS + +  L +P   PQ  
Sbjct: 4029 VD-PAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPS 4087

Query: 1219 PMETSQPYEEVSQPCQEV 1236
             ++   P     Q  Q+V
Sbjct: 4088 SLQLQPPLRLPGQQQQQV 4105



 Score = 34.3 bits (77), Expect = 0.87
 Identities = 49/164 (29%), Positives = 67/164 (40%), Gaps = 22/164 (13%)

Query: 1102 SAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTTV 1161
            S  L +S  S    ++P SPP    S P    + S   P   S PS  + +  P SP   
Sbjct: 486  SRPLEESPLSPPPEESPLSPPP--ESSPFSPLEESPLSPPEESPPSPALET--PLSPPPE 541

Query: 1162 DGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEP--NQSPQVPP 1219
                   F + P   S   EE      L  +P   A  LS   E+    P   +SP  PP
Sbjct: 542  ASPLSPPFEESPL--SPPPEE------LPTSPPPEASRLSPPPEESPMSPPPEESPMSPP 593

Query: 1220 METSQ---PYEE--VSQPCQEVPDISQPCQDISEALSQPCQKVP 1258
             E S+   P+EE  +S P +E P +S P +  +  LS P +  P
Sbjct: 594  PEASRLFPPFEESPLSPPPEESP-LSPPPE--ASRLSPPPEDSP 634



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 37/142 (26%), Positives = 49/142 (34%), Gaps = 29/142 (20%)

Query: 1139 PPWYSSGPSSTVSSA--GPSSPTTVDGNSQFGFSDQPSLNSH------------------ 1178
            PP+  S  +  V     G SSP+   G    GF D PS  +H                  
Sbjct: 2276 PPFGESRKALEVKKEELGASSPSY--GPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP 2333

Query: 1179 ----VAEEHQGLGLL-QETPGSGAQELSIEGEQELFEPNQ--SPQVPPMETSQPYEEVSQ 1231
                V  +  GLGL  QE P + A   S     ++F P     P   P  T +P     +
Sbjct: 2334 RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE 2393

Query: 1232 PCQEVPDISQPCQDISEALSQP 1253
             C  +P  S P    S   + P
Sbjct: 2394 SCCALPPRSLPSDPFSRVPASP 2415


>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 38.9 bits (89), Expect = 0.035
 Identities = 75/337 (22%), Positives = 116/337 (34%), Gaps = 44/337 (13%)

Query: 1092 QRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVS 1151
            Q H + + Q    L D   SS   + P   P+ L   P  +QQ +   P  SS  S T+ 
Sbjct: 217  QFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLP 276

Query: 1152 SAGPSSPTTVDGNSQFGFSD--------QPSLNSHVAEEHQGLGLLQETPGSGAQELSIE 1203
            +   S     +  + +   +        + ++ S    E +     QETP    +E+   
Sbjct: 277  NHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEV--- 333

Query: 1204 GEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQ 1263
                  EP+ + Q  P+E   P  E      E     QP +   E  S P Q+  +   Q
Sbjct: 334  ------EPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQ--ETPGQ 385

Query: 1264 CQENHD-----NGNHTCQEV--PHIS-QPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQ 1315
              E+H+      G+H    +  P +S +P      +  + S EV    +           
Sbjct: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGS 445

Query: 1316 GVSVEVGKLVHKFHVGVGSLVQETLVEVGSPA----------EEIPEEVIQPYQEFSVEV 1365
            G  VE   + H    G   L+ E+  E G  A          E I  E   P Q+ +   
Sbjct: 446  GNDVEPPAIQH----GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501

Query: 1366 GRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQAQE 1402
                 E    +L  Q  P     + EFP  +  Q  E
Sbjct: 502  HPQTAEEGESSLTHQEAP---AQTPEFPNVVVAQPPE 535


>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
          Length = 1700

 Score = 38.9 bits (89), Expect = 0.035
 Identities = 75/337 (22%), Positives = 116/337 (34%), Gaps = 44/337 (13%)

Query: 1092 QRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVS 1151
            Q H + + Q    L D   SS   + P   P+ L   P  +QQ +   P  SS  S T+ 
Sbjct: 217  QFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLP 276

Query: 1152 SAGPSSPTTVDGNSQFGFSD--------QPSLNSHVAEEHQGLGLLQETPGSGAQELSIE 1203
            +   S     +  + +   +        + ++ S    E +     QETP    +E+   
Sbjct: 277  NHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEV--- 333

Query: 1204 GEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQ 1263
                  EP+ + Q  P+E   P  E      E     QP +   E  S P Q+  +   Q
Sbjct: 334  ------EPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQ--ETPGQ 385

Query: 1264 CQENHD-----NGNHTCQEV--PHIS-QPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQ 1315
              E+H+      G+H    +  P +S +P      +  + S EV    +           
Sbjct: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGS 445

Query: 1316 GVSVEVGKLVHKFHVGVGSLVQETLVEVGSPA----------EEIPEEVIQPYQEFSVEV 1365
            G  VE   + H    G   L+ E+  E G  A          E I  E   P Q+ +   
Sbjct: 446  GNDVEPPAIQH----GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501

Query: 1366 GRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQAQE 1402
                 E    +L  Q  P     + EFP  +  Q  E
Sbjct: 502  HPQTAEEGESSLTHQEAP---AQTPEFPNVVVAQPPE 535


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 38.5 bits (88), Expect = 0.046
 Identities = 69/319 (21%), Positives = 106/319 (33%), Gaps = 76/319 (23%)

Query: 919  PAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTSPQPPEGPGLPRRSPLIRN 978
            P      PA S ++E+ T Q       P   +      +   PQ P  P  P R P+   
Sbjct: 1814 PGNGNMSPAQSFHKELFTKQP------PSTPTSTSSDDVFVKPQAPPPPPAPSRIPI--- 1864

Query: 979  RKAGSMEVLSETSSSRPGGYRLFS----SSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSA 1034
                  + LS+  +S+P   ++FS    +SRPP+ M                        
Sbjct: 1865 -----QDSLSQAQTSQPPSPQVFSPGSSNSRPPSPM------------------------ 1895

Query: 1035 PNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRH 1094
                 YA+  G   PP            + V    PL ++   L + + +          
Sbjct: 1896 ---DPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETT---------- 1942

Query: 1095 TDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTVSSAG 1154
                A   + + D   SS  +++P++ P             + +P      P S   S  
Sbjct: 1943 ----ANRPSPVRDLCSSSTTNNDPYAKPPD-----------TPRPVMTDQFPKSLGLSRS 1987

Query: 1155 PS-SPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFE-PN 1212
            P  S  T  G    G SD  +  S  A+  Q     Q  P S A+ L      +    P 
Sbjct: 1988 PVVSEQTAKGPIAAGTSDHFTKPSPRADVFQR----QRIPDSYARPLLTPAPLDSGPGPF 2043

Query: 1213 QSPQVPPMETSQPYEEVSQ 1231
            ++P  PP  +  PY  VSQ
Sbjct: 2044 KTPMQPPPSSQDPYGSVSQ 2062


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 38.5 bits (88), Expect = 0.046
 Identities = 73/303 (24%), Positives = 110/303 (36%), Gaps = 36/303 (11%)

Query: 891  QDPLSEERFHVELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKA- 949
            Q P  E+   +  H+ P      E+  +P    F  +  + EE +++  S  ++C     
Sbjct: 582  QSPQGEDS--LSPHYFPQSPPQGEDSMSPLY--FPQSPLQGEEFQSSLQSPVSICSSSTP 637

Query: 950  SDEPDRALQTSPQPPEGP-GLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPT 1008
            S  P    ++S  PPEGP   P  SP        S   L    S+  G       S  P 
Sbjct: 638  SSLPQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPESAPEG-----EDSLSPL 692

Query: 1009 EMKQSGLGSQCTGLFSTTVLGGSSSAPNLQD-YARSHGKKLPPASLKHRDGFEG----CS 1063
            ++ QS L     G  S + L    S P  +D  +  H  + PP     +   +     CS
Sbjct: 693  QIPQSPL----EGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQSSLQSPVSICS 748

Query: 1064 MVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPR 1123
               ++   ++   +          S + +  +   +   A+L  S H S     P SPP 
Sbjct: 749  SSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHES-----PQSPPE 803

Query: 1124 TLHSPPLQL----------QQRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQP 1173
                 PLQ              S+  P  SS PSST SS   SSP +   +    FS   
Sbjct: 804  GPAQSPLQSPVSSFPSSTSSSLSQSSP-VSSFPSSTSSSLSKSSPESPLQSPVISFSSST 862

Query: 1174 SLN 1176
            SL+
Sbjct: 863  SLS 865


>gi|59853352 myosin VIIA and Rab interacting protein [Homo sapiens]
          Length = 859

 Score = 38.1 bits (87), Expect = 0.060
 Identities = 66/287 (22%), Positives = 110/287 (38%), Gaps = 32/287 (11%)

Query: 958  QTSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGS 1017
            ++  Q  E PG P       + ++ S +V  E +S+ PGGY      R P  + +S    
Sbjct: 251  KSEQQVEEEPGWP-------HPQSCSTKVADEGTSASPGGY------RAPAALWRSQSAF 297

Query: 1018 QCTG--LFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLH 1075
              TG     T  +   S  P  Q         LP  S K  D  +  ++ P +   +   
Sbjct: 298  SITGEEALKTPPVEAPSRQPRDQGQHPRAESALP--SWKSVDRLDETNLAPVLQSPD--G 353

Query: 1076 NALSLRQVSEFLSRVCQRHTDAQAQA------SAALFDSMHSSQASDNPFSPPRTLHSPP 1129
            N ++L+  +   +R+  +      QA       A+ +D M S    D  +S   +   P 
Sbjct: 354  NWVALKDGAPPPTRLLAKPKSGTFQALEVASSVASAYDEMGSDSEEDFDWSEALSKLCPR 413

Query: 1130 LQLQQRSEKP-PWYSSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQG-LG 1187
             +   R+ +P P  +        +A PSS  + +  +    S+  S  S     HQ  L 
Sbjct: 414  SRALPRNPQPQPTQAQSSDQGPIAASPSSALSPNPEAMCSDSETSSAGSSREVGHQARLS 473

Query: 1188 LLQETP--GSGAQELSIEGEQELFEPNQSPQVPPMETSQPYEEVSQP 1232
             LQ        A+++ + GE ++   N +PQ+   ETS   E    P
Sbjct: 474  WLQRKAPRNPAAEKMRLHGELDV---NFNPQLASRETSDSSEPEEAP 517


>gi|122937239 zinc finger CCCH-type domain containing 5 [Homo
           sapiens]
          Length = 886

 Score = 37.7 bits (86), Expect = 0.079
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 8/110 (7%)

Query: 895 SEERFHVELHFSPGVKGVEEEGSAPAG--CGFRPASSE--NEEMKTNQGSMENLCPGKAS 950
           +E++FH E++ S     +++ GS P G  C F        +++++ +        PG   
Sbjct: 361 TEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLSDDLQPSSAVSSPTQPGPVL 420

Query: 951 DEPDRALQTSPQPPEGPGLPRRSPLI-RNRKAGSMEVLSETSSSRPGGYR 999
             P  A  + P  P  P  P  S L+ RN   GS    S    S PG  R
Sbjct: 421 YMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSP---SNLCGSPPGSIR 467


>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
          Length = 2030

 Score = 37.4 bits (85), Expect = 0.10
 Identities = 62/262 (23%), Positives = 89/262 (33%), Gaps = 40/262 (15%)

Query: 921  GCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTSPQPPEGPGLPRRSPLIRNRK 980
            G G   +SS +    +  G+M  L  G   D P+            P           R 
Sbjct: 1675 GTGRHSSSSLSSHASSEAGNMVMLGDGSMGDAPEDLYHHMQLAYPNP-----------RY 1723

Query: 981  AGSMEVLSETSSSR--PGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQ 1038
             GS+  +S  SSS+  P    L S+   P++M  S   S            GS S P+  
Sbjct: 1724 QGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSA----------RGSPSLPDKY 1773

Query: 1039 DYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALS---LRQVSEFLSRVCQRHT 1095
             +AR     LP     +RD          +YP   L N       R + + +   C+  +
Sbjct: 1774 RHAREMMLLLPT----YRDRPSSA-----MYPAAILENGQPPNFQRALFQQVVGACKPCS 1824

Query: 1096 DAQAQAS-----AALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPPWYSSGPSSTV 1150
            D     +     +  FD+ H       P  P RTL   PL     S   P      S++ 
Sbjct: 1825 DPNLSVAEKGHYSLHFDAFHHPLGDTPPALPARTLRKSPLHPIPASPTSPQSGLDGSNST 1884

Query: 1151 SSAGPSSPTTVDGNSQFGFSDQ 1172
             S   SS  +    S FG S +
Sbjct: 1885 LSGSASSGVSSLSESNFGHSSE 1906


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 37.4 bits (85), Expect = 0.10
 Identities = 35/138 (25%), Positives = 55/138 (39%), Gaps = 9/138 (6%)

Query: 1100 QASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQR---SEKPPWYSSGPSSTVSSAGPS 1156
            Q +AA      SSQ+S  P  P   L   P+        +  PP  S+GPS  V+S  P 
Sbjct: 645  QLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPL 704

Query: 1157 SPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQ 1216
            S + +  +S   FS    L    A   Q +  +++ P      L         E   SP+
Sbjct: 705  SKSALPYSS---FSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLE---SPR 758

Query: 1217 VPPMETSQPYEEVSQPCQ 1234
             P  +  + +E++   C+
Sbjct: 759  GPRFDGPRRFEDLGSRCE 776



 Score = 31.2 bits (69), Expect = 7.3
 Identities = 37/129 (28%), Positives = 46/129 (35%), Gaps = 22/129 (17%)

Query: 1115 SDNPFSPPRT---LHSPPLQLQQRSEKPPWYSSGPSSTVS------------SAGPSSPT 1159
            S  P+ PP       SPP Q        P YSS  SS+ S             A PS P+
Sbjct: 179  SSQPYLPPAQPSPSQSPPSQ--SYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPS 236

Query: 1160 TVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPP 1219
                 SQ      PS     A       + QE   SGA+  S E +Q   EP+ S   P 
Sbjct: 237  QGHSKSQLLAPPPPS-----APPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQ 291

Query: 1220 METSQPYEE 1228
             +    Y +
Sbjct: 292  EQQQYWYRQ 300


>gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]
          Length = 554

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 62/254 (24%), Positives = 88/254 (34%), Gaps = 61/254 (24%)

Query: 909  VKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTSPQPPEGPG 968
            +K VE+E  +P            E   T QG      PG  S       Q+S      PG
Sbjct: 323  LKSVEDEMDSPG----------EEPFYTGQGRS----PGSGS-------QSSGWHEVEPG 361

Query: 969  LPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVL 1028
            +P  + L ++ K+G                  FSS   P+  + S LG+  T      + 
Sbjct: 362  MPSPTTLKKSEKSG------------------FSS---PSPSQTSSLGTAFTQHHRPVIT 400

Query: 1029 GGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLS 1088
            G     P    +A       P + +  + G          +P ETL          EF+ 
Sbjct: 401  G-----PRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETL---------KEFVQ 446

Query: 1089 RVCQRHTDAQAQASAALFDSMHSSQASD--NPFSPPRTLHSPPLQLQQRSEKPPWYSSGP 1146
             VC    DA  QA    F + + S      NPF P   L  PP     R    P   + P
Sbjct: 447  LVCP---DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 503

Query: 1147 SSTVSSAGPSSPTT 1160
             +T +  G +SPT+
Sbjct: 504  PTTSTEGGAASPTS 517


>gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]
          Length = 501

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 62/254 (24%), Positives = 88/254 (34%), Gaps = 61/254 (24%)

Query: 909  VKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTSPQPPEGPG 968
            +K VE+E  +P            E   T QG      PG  S       Q+S      PG
Sbjct: 270  LKSVEDEMDSPG----------EEPFYTGQGRS----PGSGS-------QSSGWHEVEPG 308

Query: 969  LPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVL 1028
            +P  + L ++ K+G                  FSS   P+  + S LG+  T      + 
Sbjct: 309  MPSPTTLKKSEKSG------------------FSS---PSPSQTSSLGTAFTQHHRPVIT 347

Query: 1029 GGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLS 1088
            G     P    +A       P + +  + G          +P ETL          EF+ 
Sbjct: 348  G-----PRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETL---------KEFVQ 393

Query: 1089 RVCQRHTDAQAQASAALFDSMHSSQASD--NPFSPPRTLHSPPLQLQQRSEKPPWYSSGP 1146
             VC    DA  QA    F + + S      NPF P   L  PP     R    P   + P
Sbjct: 394  LVCP---DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 450

Query: 1147 SSTVSSAGPSSPTT 1160
             +T +  G +SPT+
Sbjct: 451  PTTSTEGGAASPTS 464


>gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]
          Length = 498

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 62/254 (24%), Positives = 88/254 (34%), Gaps = 61/254 (24%)

Query: 909  VKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTSPQPPEGPG 968
            +K VE+E  +P            E   T QG      PG  S       Q+S      PG
Sbjct: 278  LKSVEDEMDSPG----------EEPFYTGQGRS----PGSGS-------QSSGWHEVEPG 316

Query: 969  LPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVL 1028
            +P  + L ++ K+G                  FSS   P+  + S LG+  T      + 
Sbjct: 317  MPSPTTLKKSEKSG------------------FSS---PSPSQTSSLGTAFTQHHRPVIT 355

Query: 1029 GGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLS 1088
            G     P    +A       P + +  + G          +P ETL          EF+ 
Sbjct: 356  G-----PRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETL---------KEFVQ 401

Query: 1089 RVCQRHTDAQAQASAALFDSMHSSQASD--NPFSPPRTLHSPPLQLQQRSEKPPWYSSGP 1146
             VC    DA  QA    F + + S      NPF P   L  PP     R    P   + P
Sbjct: 402  LVCP---DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 458

Query: 1147 SSTVSSAGPSSPTT 1160
             +T +  G +SPT+
Sbjct: 459  PTTSTEGGAASPTS 472


>gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]
          Length = 509

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 62/254 (24%), Positives = 88/254 (34%), Gaps = 61/254 (24%)

Query: 909  VKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTSPQPPEGPG 968
            +K VE+E  +P            E   T QG      PG  S       Q+S      PG
Sbjct: 278  LKSVEDEMDSPG----------EEPFYTGQGRS----PGSGS-------QSSGWHEVEPG 316

Query: 969  LPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVL 1028
            +P  + L ++ K+G                  FSS   P+  + S LG+  T      + 
Sbjct: 317  MPSPTTLKKSEKSG------------------FSS---PSPSQTSSLGTAFTQHHRPVIT 355

Query: 1029 GGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSLRQVSEFLS 1088
            G     P    +A       P + +  + G          +P ETL          EF+ 
Sbjct: 356  G-----PRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETL---------KEFVQ 401

Query: 1089 RVCQRHTDAQAQASAALFDSMHSSQASD--NPFSPPRTLHSPPLQLQQRSEKPPWYSSGP 1146
             VC    DA  QA    F + + S      NPF P   L  PP     R    P   + P
Sbjct: 402  LVCP---DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 458

Query: 1147 SSTVSSAGPSSPTT 1160
             +T +  G +SPT+
Sbjct: 459  PTTSTEGGAASPTS 472


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,403,207
Number of Sequences: 37866
Number of extensions: 3040682
Number of successful extensions: 9353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 202
Number of HSP's that attempted gapping in prelim test: 8772
Number of HSP's gapped (non-prelim): 599
length of query: 1408
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1293
effective length of database: 13,892,928
effective search space: 17963555904
effective search space used: 17963555904
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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