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Search of human proteins with 194306559
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
(618 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 1225 0.0
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 1098 0.0
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 1097 0.0
gi|41871960 kinesin-like 8 isoform b [Homo sapiens] 808 0.0
gi|41871955 kinesin-like 8 isoform a [Homo sapiens] 808 0.0
gi|41871946 kinesin-like 8 isoform a [Homo sapiens] 808 0.0
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens] 794 0.0
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens] 794 0.0
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens] 794 0.0
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens] 626 e-179
gi|91825557 kinesin light chain 3 [Homo sapiens] 513 e-145
gi|19923891 kinesin-like 8 isoform c [Homo sapiens] 400 e-111
gi|34304360 nephrocystin 3 [Homo sapiens] 157 2e-38
gi|87162455 hypothetical protein LOC23277 [Homo sapiens] 65 2e-10
gi|18104962 amyloid beta precursor protein-binding protein 2 [Ho... 61 3e-09
gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens] 56 9e-08
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 53 7e-07
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 53 7e-07
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s... 50 6e-06
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa... 50 6e-06
gi|38044112 restin isoform b [Homo sapiens] 50 8e-06
gi|4506751 restin isoform a [Homo sapiens] 50 8e-06
gi|83415184 transmembrane and tetratricopeptide repeat containin... 50 8e-06
gi|110815815 centlein isoform 1 [Homo sapiens] 49 1e-05
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 48 3e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 47 4e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 47 4e-05
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 47 7e-05
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 46 9e-05
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 46 9e-05
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 1225 bits (3169), Expect = 0.0
Identities = 618/618 (100%), Positives = 618/618 (100%)
Query: 1 MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD 60
MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD
Sbjct: 1 MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD 60
Query: 61 ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL 120
ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL
Sbjct: 61 ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL 120
Query: 121 RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF 180
RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF
Sbjct: 121 RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF 180
Query: 181 PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL 240
PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL
Sbjct: 181 PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL 240
Query: 241 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL 300
EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL
Sbjct: 241 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL 300
Query: 301 NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY 360
NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY
Sbjct: 301 NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY 360
Query: 361 YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD 420
YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD
Sbjct: 361 YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD 420
Query: 421 DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF 480
DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF
Sbjct: 421 DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF 480
Query: 481 EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE 540
EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE
Sbjct: 481 EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE 540
Query: 541 EVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEP 600
EVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEP
Sbjct: 541 EVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEP 600
Query: 601 LFVENDSSSSGLEDATAN 618
LFVENDSSSSGLEDATAN
Sbjct: 601 LFVENDSSSSGLEDATAN 618
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 1098 bits (2841), Expect = 0.0
Identities = 551/554 (99%), Positives = 552/554 (99%)
Query: 1 MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD 60
MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD
Sbjct: 1 MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD 60
Query: 61 ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL 120
ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL
Sbjct: 61 ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL 120
Query: 121 RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF 180
RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF
Sbjct: 121 RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF 180
Query: 181 PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL 240
PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL
Sbjct: 181 PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL 240
Query: 241 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL 300
EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL
Sbjct: 241 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL 300
Query: 301 NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY 360
NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY
Sbjct: 301 NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY 360
Query: 361 YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD 420
YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD
Sbjct: 361 YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD 420
Query: 421 DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF 480
DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF
Sbjct: 421 DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF 480
Query: 481 EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE 540
EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE
Sbjct: 481 EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE 540
Query: 541 EVSMSVEWNGDGTG 554
EVSMSVEWNG +G
Sbjct: 541 EVSMSVEWNGGVSG 554
>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
Length = 560
Score = 1097 bits (2838), Expect = 0.0
Identities = 550/550 (100%), Positives = 550/550 (100%)
Query: 1 MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD 60
MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD
Sbjct: 1 MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD 60
Query: 61 ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL 120
ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL
Sbjct: 61 ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL 120
Query: 121 RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF 180
RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF
Sbjct: 121 RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF 180
Query: 181 PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL 240
PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL
Sbjct: 181 PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL 240
Query: 241 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL 300
EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL
Sbjct: 241 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL 300
Query: 301 NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY 360
NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY
Sbjct: 301 NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY 360
Query: 361 YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD 420
YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD
Sbjct: 361 YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD 420
Query: 421 DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF 480
DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF
Sbjct: 421 DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF 480
Query: 481 EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE 540
EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE
Sbjct: 481 EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE 540
Query: 541 EVSMSVEWNG 550
EVSMSVEWNG
Sbjct: 541 EVSMSVEWNG 550
>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
Length = 637
Score = 808 bits (2088), Expect = 0.0
Identities = 414/600 (69%), Positives = 497/600 (82%), Gaps = 16/600 (2%)
Query: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 34 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 93
Query: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 94 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 153
Query: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDED-DPGQGIQQQH 195
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN+E+ DP G+ +
Sbjct: 154 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 211
Query: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 212 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 271
Query: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 315
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 272 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 331
Query: 316 AEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGP 375
AEPLC+RALEIREKVLG +HPDVAKQLNNLALLCQNQGKYE VE YYQRAL IY+ +LGP
Sbjct: 332 AEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGP 391
Query: 376 DDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
D+PNVA+TKNNLASCYLKQGK+ +AETLYKEILTRAH +EFGSVDD++KPIWMHAEEREE
Sbjct: 392 DNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREE 451
Query: 436 CKGKQ--KDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRS 493
+ + GT + EYGGWYKACKV SPTV TTL+NLGALYRRQGK EAAETLEE A+RS
Sbjct: 452 MSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRS 511
Query: 494 RKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNGDGT 553
R+QG D + + +VAE+L + + RR+ + D VK+E GGE+ S++VEW+GDG+
Sbjct: 512 RRQGTDPISQTKVAELLGESDG---RRTSQEGPGDSVKFE----GGEDASVAVEWSGDGS 564
Query: 554 GSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEPLFVENDSSSSGLE 613
G+L+RSGS K+R +RRSSE LVRKL+G E P + A L N S++ L+
Sbjct: 565 GTLQRSGSLGKIRDVLRRSSELLVRKLQG---TEPRPSSSNMKRAASLNYLNQPSAAPLQ 621
>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 808 bits (2088), Expect = 0.0
Identities = 414/600 (69%), Positives = 497/600 (82%), Gaps = 16/600 (2%)
Query: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 16 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 75
Query: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 76 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 135
Query: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDED-DPGQGIQQQH 195
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN+E+ DP G+ +
Sbjct: 136 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 193
Query: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 194 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 253
Query: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 315
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 254 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 313
Query: 316 AEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGP 375
AEPLC+RALEIREKVLG +HPDVAKQLNNLALLCQNQGKYE VE YYQRAL IY+ +LGP
Sbjct: 314 AEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGP 373
Query: 376 DDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
D+PNVA+TKNNLASCYLKQGK+ +AETLYKEILTRAH +EFGSVDD++KPIWMHAEEREE
Sbjct: 374 DNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREE 433
Query: 436 CKGKQ--KDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRS 493
+ + GT + EYGGWYKACKV SPTV TTL+NLGALYRRQGK EAAETLEE A+RS
Sbjct: 434 MSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRS 493
Query: 494 RKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNGDGT 553
R+QG D + + +VAE+L + + RR+ + D VK+E GGE+ S++VEW+GDG+
Sbjct: 494 RRQGTDPISQTKVAELLGESDG---RRTSQEGPGDSVKFE----GGEDASVAVEWSGDGS 546
Query: 554 GSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEPLFVENDSSSSGLE 613
G+L+RSGS K+R +RRSSE LVRKL+G E P + A L N S++ L+
Sbjct: 547 GTLQRSGSLGKIRDVLRRSSELLVRKLQG---TEPRPSSSNMKRAASLNYLNQPSAAPLQ 603
>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 808 bits (2088), Expect = 0.0
Identities = 414/600 (69%), Positives = 497/600 (82%), Gaps = 16/600 (2%)
Query: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 16 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 75
Query: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 76 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 135
Query: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDED-DPGQGIQQQH 195
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN+E+ DP G+ +
Sbjct: 136 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 193
Query: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 194 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 253
Query: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 315
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 254 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 313
Query: 316 AEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGP 375
AEPLC+RALEIREKVLG +HPDVAKQLNNLALLCQNQGKYE VE YYQRAL IY+ +LGP
Sbjct: 314 AEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGP 373
Query: 376 DDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
D+PNVA+TKNNLASCYLKQGK+ +AETLYKEILTRAH +EFGSVDD++KPIWMHAEEREE
Sbjct: 374 DNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREE 433
Query: 436 CKGKQ--KDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRS 493
+ + GT + EYGGWYKACKV SPTV TTL+NLGALYRRQGK EAAETLEE A+RS
Sbjct: 434 MSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRS 493
Query: 494 RKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNGDGT 553
R+QG D + + +VAE+L + + RR+ + D VK+E GGE+ S++VEW+GDG+
Sbjct: 494 RRQGTDPISQTKVAELLGESDG---RRTSQEGPGDSVKFE----GGEDASVAVEWSGDGS 546
Query: 554 GSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEPLFVENDSSSSGLE 613
G+L+RSGS K+R +RRSSE LVRKL+G E P + A L N S++ L+
Sbjct: 547 GTLQRSGSLGKIRDVLRRSSELLVRKLQG---TEPRPSSSNMKRAASLNYLNQPSAAPLQ 603
>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 794 bits (2051), Expect = 0.0
Identities = 417/605 (68%), Positives = 486/605 (80%), Gaps = 18/605 (2%)
Query: 5 MSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL 64
M+ MV+ +E EKL+QDEI+ TK VIQGLE L+ EH ++L L+ + +
Sbjct: 1 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGEAEPG 53
Query: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
+E+ ++R+SLE +ELGL EAQV++ALS+HL AVESEKQKLRAQVRRL QENQWLR+EL
Sbjct: 54 SQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREEL 113
Query: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDE 184
A TQQKLQ+SEQ+VAQLEEEK+HL FM+Q++K D+D SP+E+K D K+ LDDLFPN++
Sbjct: 114 AGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKG-DVPKDTLDDLFPNED 172
Query: 185 DDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 244
+ Q + Q GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE
Sbjct: 173 E---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 229
Query: 245 KTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA 304
KTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLGKDHPAVAATLNNLA
Sbjct: 230 KTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA 289
Query: 305 VLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 364
VLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQNQGK EEVEYYY+R
Sbjct: 290 VLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRR 349
Query: 365 ALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENK 424
ALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTRAHE+EFGSV+ +NK
Sbjct: 350 ALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNK 409
Query: 425 PIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAE 484
PIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++LGALYRRQGK EAA
Sbjct: 410 PIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAH 469
Query: 485 TLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVDVVKYESGPDGGEEV 542
TLE+ A R+RKQGLD + +V E+L D ++R SR+ + ES E+V
Sbjct: 470 TLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDL---EDV 526
Query: 543 SMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEPLF 602
+ EWNGDG+GSL+RSGSF KLR ++RRSSE LV+KL+GG+ + EP NP A L
Sbjct: 527 GPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQ--EPPNPRMKRASSLN 584
Query: 603 VENDS 607
N S
Sbjct: 585 FLNKS 589
>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 794 bits (2051), Expect = 0.0
Identities = 417/605 (68%), Positives = 486/605 (80%), Gaps = 18/605 (2%)
Query: 5 MSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL 64
M+ MV+ +E EKL+QDEI+ TK VIQGLE L+ EH ++L L+ + +
Sbjct: 1 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGEAEPG 53
Query: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
+E+ ++R+SLE +ELGL EAQV++ALS+HL AVESEKQKLRAQVRRL QENQWLR+EL
Sbjct: 54 SQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREEL 113
Query: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDE 184
A TQQKLQ+SEQ+VAQLEEEK+HL FM+Q++K D+D SP+E+K D K+ LDDLFPN++
Sbjct: 114 AGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKG-DVPKDTLDDLFPNED 172
Query: 185 DDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 244
+ Q + Q GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE
Sbjct: 173 E---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 229
Query: 245 KTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA 304
KTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLGKDHPAVAATLNNLA
Sbjct: 230 KTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA 289
Query: 305 VLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 364
VLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQNQGK EEVEYYY+R
Sbjct: 290 VLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRR 349
Query: 365 ALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENK 424
ALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTRAHE+EFGSV+ +NK
Sbjct: 350 ALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNK 409
Query: 425 PIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAE 484
PIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++LGALYRRQGK EAA
Sbjct: 410 PIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAH 469
Query: 485 TLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVDVVKYESGPDGGEEV 542
TLE+ A R+RKQGLD + +V E+L D ++R SR+ + ES E+V
Sbjct: 470 TLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDL---EDV 526
Query: 543 SMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEPLF 602
+ EWNGDG+GSL+RSGSF KLR ++RRSSE LV+KL+GG+ + EP NP A L
Sbjct: 527 GPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQ--EPPNPRMKRASSLN 584
Query: 603 VENDS 607
N S
Sbjct: 585 FLNKS 589
>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 794 bits (2051), Expect = 0.0
Identities = 417/605 (68%), Positives = 486/605 (80%), Gaps = 18/605 (2%)
Query: 5 MSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL 64
M+ MV+ +E EKL+QDEI+ TK VIQGLE L+ EH ++L L+ + +
Sbjct: 1 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGEAEPG 53
Query: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
+E+ ++R+SLE +ELGL EAQV++ALS+HL AVESEKQKLRAQVRRL QENQWLR+EL
Sbjct: 54 SQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREEL 113
Query: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDE 184
A TQQKLQ+SEQ+VAQLEEEK+HL FM+Q++K D+D SP+E+K D K+ LDDLFPN++
Sbjct: 114 AGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKG-DVPKDTLDDLFPNED 172
Query: 185 DDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 244
+ Q + Q GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE
Sbjct: 173 E---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 229
Query: 245 KTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA 304
KTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLGKDHPAVAATLNNLA
Sbjct: 230 KTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA 289
Query: 305 VLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 364
VLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQNQGK EEVEYYY+R
Sbjct: 290 VLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRR 349
Query: 365 ALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENK 424
ALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTRAHE+EFGSV+ +NK
Sbjct: 350 ALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNK 409
Query: 425 PIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAE 484
PIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++LGALYRRQGK EAA
Sbjct: 410 PIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAH 469
Query: 485 TLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVDVVKYESGPDGGEEV 542
TLE+ A R+RKQGLD + +V E+L D ++R SR+ + ES E+V
Sbjct: 470 TLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDL---EDV 526
Query: 543 SMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEPLF 602
+ EWNGDG+GSL+RSGSF KLR ++RRSSE LV+KL+GG+ + EP NP A L
Sbjct: 527 GPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQ--EPPNPRMKRASSLN 584
Query: 603 VENDS 607
N S
Sbjct: 585 FLNKS 589
>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
Length = 545
Score = 626 bits (1614), Expect = e-179
Identities = 328/499 (65%), Positives = 382/499 (76%), Gaps = 10/499 (2%)
Query: 111 RRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTD 170
+ + Q + LR E L E A+ +++ + L+ + + ++++ D
Sbjct: 22 KAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQEEKGD 81
Query: 171 STKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYE 230
K+ LDDLFPN+++ Q + Q GGYEIPARLRTLHNLVIQYASQGRYE
Sbjct: 82 VPKDTLDDLFPNEDE---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYE 138
Query: 231 VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLG 290
VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLG
Sbjct: 139 VAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLG 198
Query: 291 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQ 350
KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQ
Sbjct: 199 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQ 258
Query: 351 NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTR 410
NQGK EEVEYYY+RALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTR
Sbjct: 259 NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR 318
Query: 411 AHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNL 470
AHE+EFGSV+ +NKPIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++L
Sbjct: 319 AHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSL 378
Query: 471 GALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVD 528
GALYRRQGK EAA TLE+ A R+RKQGLD + +V E+L D ++R SR+
Sbjct: 379 GALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGA 438
Query: 529 VVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRES 588
+ ES E+V + EWNGDG+GSL+RSGSF KLR ++RRSSE LV+KL+GG+ +
Sbjct: 439 GPRSESDL---EDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQ-- 493
Query: 589 EPKNPGASLAEPLFVENDS 607
EP NP A L N S
Sbjct: 494 EPPNPRMKRASSLNFLNKS 512
Score = 143 bits (361), Expect = 4e-34
Identities = 128/413 (30%), Positives = 195/413 (47%), Gaps = 33/413 (7%)
Query: 5 MSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL 64
M+ MV+ +E EKL+QDEI+ TK VIQGLE L+ EH ++L L+ + +
Sbjct: 1 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGEAEPG 53
Query: 65 VEEKSNMIRKSLEMLELGLSEAQ-----VMMALSNHLNAVESEKQKLRAQVRRLCQENQW 119
+E+ ++R+SLE +ELGL EAQ V + L E E+ +
Sbjct: 54 SQERCILLRRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHG 113
Query: 120 LRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLD-- 177
+ A +L+ V Q + ++ + K+ +D+ + D L+
Sbjct: 114 GYEIPA----RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNIL 169
Query: 178 DLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCK 237
L D++ + + + A + G + PA TL+NL + Y +G+Y+ A PLCK
Sbjct: 170 ALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCK 229
Query: 238 QALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVA 297
+ALE EK G HPDVA L+ LAL+ ++Q K ++ AL I LG D P VA
Sbjct: 230 RALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVA 289
Query: 298 ATLNNLAVLYGKRGKYKEAEPLCKRAL-EIREKVLGKDHPD------VAKQLNNLALLCQ 350
T NNLA Y K+GKY++AE L K L EK G + D A++ +
Sbjct: 290 KTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRR 349
Query: 351 NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETL 403
+ Y E +Y +A ++ D P V T +L + Y +QGK + A TL
Sbjct: 350 DSAPYGEYGSWY-KACKV-------DSPTVNTTLRSLGALYRRQGKLEAAHTL 394
>gi|91825557 kinesin light chain 3 [Homo sapiens]
Length = 504
Score = 513 bits (1321), Expect = e-145
Identities = 259/392 (66%), Positives = 321/392 (81%), Gaps = 5/392 (1%)
Query: 17 EKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSNMIRKSL 76
E+L+ +E++ +T+QV+QGLEAL+ EH+ + L E L ++EEK ++ SL
Sbjct: 16 ERLSPEELVRQTRQVVQGLEALRAEHHGLAGHLAEALAGQGPAAGLEMLEEKQQVVSHSL 75
Query: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
E +ELGL EAQV++ALS H+ A+E+EKQ+LR+Q RRL QEN WLR+EL TQ++L+ SE+
Sbjct: 76 EAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEE 135
Query: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDEDDPGQGIQQQHS 196
SVAQLEEEK+HLEF+ QL++YD + S+ ++ ++ L LFP++E++ + +
Sbjct: 136 SVAQLEEEKRHLEFLGQLRQYDPP-AESQQSESPPRRDSLASLFPSEEEER----KGPEA 190
Query: 197 SAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVAT 256
+ AAAAQQGGYEIPARLRTLHNLVIQYA QGRYEVAVPLC+QALEDLE++SGH HPDVAT
Sbjct: 191 AGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVAT 250
Query: 257 MLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEA 316
MLNILALVYRDQNKYK+A +LL+DAL IRE+TLG +HPAVAATLNNLAVLYGKRG+Y+EA
Sbjct: 251 MLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREA 310
Query: 317 EPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPD 376
EPLC+RALEIREKVLG DHPDVAKQLNNLALLCQNQGK+E+VE +Y RAL IY+ GP
Sbjct: 311 EPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPH 370
Query: 377 DPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 408
DPNVAKTKNNLAS YLKQ K++QAE LYKEIL
Sbjct: 371 DPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Score = 137 bits (346), Expect = 2e-32
Identities = 104/299 (34%), Positives = 143/299 (47%), Gaps = 52/299 (17%)
Query: 290 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLC 349
G + PA TL+NL + Y +G+Y+ A PLC++ALE E+ G HPDVA LN LAL+
Sbjct: 200 GYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVY 259
Query: 350 QNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILT 409
++Q KY+E AL+I + LGP+ P VA T NNLA Y K+G++++AE L + L
Sbjct: 260 RDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRAL- 318
Query: 410 RAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKN 469
E RE+ G D P V L N
Sbjct: 319 ---------------------EIREKVLG-------------------ADHPDVAKQLNN 338
Query: 470 LGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPEN----MEKRRSRESL 525
L L + QGKFE E A+ S + L H VA+ N+ + K + E L
Sbjct: 339 LALLCQNQGKFEDVERHYARAL-SIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEEL 397
Query: 526 NVDVVKYES--GPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKG 582
+++ E P G + GD +L+RS S SK+R SIRR SEKLV +L+G
Sbjct: 398 YKEILHKEDLPAPLGAPNTGTA----GDAEQALRRSSSLSKIRESIRRGSEKLVSRLRG 452
>gi|19923891 kinesin-like 8 isoform c [Homo sapiens]
Length = 315
Score = 400 bits (1029), Expect = e-111
Identities = 201/282 (71%), Positives = 245/282 (86%), Gaps = 4/282 (1%)
Query: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSNMIRKSL 76
+L+Q+EI+ T+ V QGLEAL++EH ++LQSL +T++CL++ E LV EK+ +R+S+
Sbjct: 16 RLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSM 75
Query: 77 EMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQ 136
E +ELGLSEAQVM+AL++HL+ VESEKQKLRAQVRRLCQENQWLRDELA TQQ+LQ+SEQ
Sbjct: 76 ENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQ 135
Query: 137 SVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPN-DEDDPGQGIQQQH 195
+VAQLEEEKKHLEF+ QL++YD+D SE+K+ D+TK+ LDDLFPN +E+DP G+ +
Sbjct: 136 AVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGLSR-- 193
Query: 196 SSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 255
A AAQQGGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPDVA
Sbjct: 194 GQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVA 253
Query: 256 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVA 297
TMLNILALVYRDQNKYK+AA+LLNDAL+IRE TLG DHPAV+
Sbjct: 254 TMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
Score = 85.9 bits (211), Expect = 1e-16
Identities = 43/92 (46%), Positives = 60/92 (65%)
Query: 290 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLC 349
G + PA TL+NL + Y +G+Y+ A PLCK+ALE E+ G+ HPDVA LN LAL+
Sbjct: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
Query: 350 QNQGKYEEVEYYYQRALEIYQTKLGPDDPNVA 381
++Q KY+E + AL I ++ LGPD P V+
Sbjct: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
Score = 41.2 bits (95), Expect = 0.003
Identities = 26/78 (33%), Positives = 39/78 (50%)
Query: 332 GKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCY 391
G + P + L+NL + QG+YE ++ALE + G P+VA N LA Y
Sbjct: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
Query: 392 LKQGKFKQAETLYKEILT 409
Q K+K+A L + L+
Sbjct: 264 RDQNKYKEAAHLLNDALS 281
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 157 bits (398), Expect = 2e-38
Identities = 149/501 (29%), Positives = 211/501 (42%), Gaps = 101/501 (20%)
Query: 69 SNMIRKSLEMLELGLSEAQVMMALSNHLNAV---ESEKQKLRAQVRRL-CQENQWLRD-- 122
S+ +K + L LS+ +V ++ L + + KQKL + L +N + R
Sbjct: 842 SSYRQKLINYFTLQLSQDRVTWRSADELPWLFQQQGSKQKLHDCLLNLFVSQNLYKRGHF 901
Query: 123 -ELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFP 181
EL + Q + K + ++A E+ + LK+Y+ + E +D S L +
Sbjct: 902 AELLSYWQFVGKDKSAMAT--------EYFDSLKQYEKNC---EGEDNMSCLADLYETLG 950
Query: 182 NDEDDPG---QGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQ 238
D G Q I S + P ++LH L Y ++ A L KQ
Sbjct: 951 RFLKDLGLLSQAIVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQ 1010
Query: 239 ALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDA------------------------ 274
ALE E G DHP A L LA +Y+ QNKY+ A
Sbjct: 1011 ALEISENAYGADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGF 1070
Query: 275 ANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKD 334
A L AL + E TLGKD P A TLN L VLY + + A+ KR+LE+RE+VLG D
Sbjct: 1071 ALLRRRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPD 1130
Query: 335 HPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQ 394
HPD A+ LNNLA LC + +Y++ E Y+RAL+I + L PD P++A T +LA Y K
Sbjct: 1131 HPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKM 1190
Query: 395 GKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYK 454
GK +A LY E+ ++ FG
Sbjct: 1191 GKLDKAVPLY-ELAVEIRQKSFGP------------------------------------ 1213
Query: 455 ACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPE 514
P+V T L NL LY + K A L E A++ + L +H RV E L
Sbjct: 1214 ----KHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMH-PRVGETLK--- 1265
Query: 515 NMEKRRSRESLNVDVVKYESG 535
N+ V+ YE G
Sbjct: 1266 -----------NLAVLSYEGG 1275
Score = 112 bits (280), Expect = 1e-24
Identities = 114/399 (28%), Positives = 181/399 (45%), Gaps = 40/399 (10%)
Query: 5 MSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL 64
+S ++ +DK T E KQ + E ++ S L L ETL KD L
Sbjct: 905 LSYWQFVGKDKSAMAT--EYFDSLKQYEKNCEG--EDNMSCLADLYETLGRFLKD--LGL 958
Query: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHL------------NAVESEKQKLRAQVRR 112
+ + +++SLE+ E L +A S H NA + KQ L
Sbjct: 959 LSQAIVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENA 1018
Query: 113 LCQENQWLRDEL---ANTQQKLQKSEQS---------VAQLEEEKK-HLEFMNQLKKYDD 159
++ + EL A QK K EQ+ + Q +KK +L L++
Sbjct: 1019 YGADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRAL 1078
Query: 160 DISP-SEDKDTDSTKEPLDDL-----FPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARL 213
+ + KDT L++L N+ + Q +++ S + G + P
Sbjct: 1079 QLEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKR---SLEMRERVLGPDHPDCA 1135
Query: 214 RTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKD 273
++L+NL + +Y+ A L ++AL+ + DHP +A + LA++Y+ K
Sbjct: 1136 QSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDK 1195
Query: 274 AANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK 333
A L A+ IR+K+ G HP+VA L NLAVLY + K+ EA PL +RAL+I E LG+
Sbjct: 1196 AVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGR 1255
Query: 334 DHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTK 372
HP V + L NLA+L G +E+ Y+RA+EI + +
Sbjct: 1256 MHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEIKEAE 1294
Score = 77.0 bits (188), Expect = 5e-14
Identities = 70/266 (26%), Positives = 114/266 (42%), Gaps = 25/266 (9%)
Query: 280 DALAIREKTL-GKDHPAVAATL-NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPD 337
D+L EK G+D+ + A L L G +A +R+LEIRE L DHP
Sbjct: 924 DSLKQYEKNCEGEDNMSCLADLYETLGRFLKDLGLLSQAIVPLQRSLEIRETALDPDHPR 983
Query: 338 VAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKF 397
VA+ L+ LA + K+ E Y++ALEI + G D P A+ LA+ Y KQ K+
Sbjct: 984 VAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHPYTARELEALATLYQKQNKY 1043
Query: 398 KQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACK 457
+QAE K+ + H++ + ++ + Q + + G+
Sbjct: 1044 EQAEHFRKKSF-KIHQKAIKKKGN------LYGFALLRRRALQLEELTLGK--------- 1087
Query: 458 VDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHK------QRVAEVLN 511
D+P TL LG LY Q E A+ + ++ R++ L H +A + N
Sbjct: 1088 -DTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCN 1146
Query: 512 DPENMEKRRSRESLNVDVVKYESGPD 537
+ + +K +D+ + PD
Sbjct: 1147 EKKQYDKAEELYERALDIRRRALAPD 1172
>gi|87162455 hypothetical protein LOC23277 [Homo sapiens]
Length = 1309
Score = 64.7 bits (156), Expect = 2e-10
Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 7/196 (3%)
Query: 226 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIR 285
QG + L +AL G H + L +LA ++ Y +A + A+ +
Sbjct: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
Query: 286 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNL 345
E+ +G +HP +LA+ + A L RA + V G+DHP++A NN+
Sbjct: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
Query: 346 ALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKF-------K 398
L+ +Y+ + + AL + GP VA + + +A Y + +F K
Sbjct: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
Query: 399 QAETLYKEILTRAHER 414
+ T+YK L HE+
Sbjct: 1171 EGYTIYKTQLGEDHEK 1186
Score = 50.4 bits (119), Expect = 5e-06
Identities = 47/205 (22%), Positives = 86/205 (41%), Gaps = 8/205 (3%)
Query: 186 DPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEK 245
D + + Q + + + G E P ++ +L + + + A+ L +A +
Sbjct: 1035 DYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLL 1094
Query: 246 TSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAV 305
G DHP++A + N + LV +Y + L +ALA+ K G VA + + +A
Sbjct: 1095 VFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVAR 1154
Query: 306 LYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRA 365
+Y + +++ A K I + LG+DH + L L Q QR
Sbjct: 1155 VYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ-------AVALQRT 1207
Query: 366 L-EIYQTKLGPDDPNVAKTKNNLAS 389
+ EIY+ + P + T ++AS
Sbjct: 1208 MNEIYRNGSSANIPPLKFTAPSMAS 1232
Score = 47.4 bits (111), Expect = 4e-05
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 5/167 (2%)
Query: 227 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
G Y A+ ++A+ E+ G +HP+ LAL ++ A +LL A +
Sbjct: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
Query: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
G+DHP +A NN+ ++ +Y + + AL + K G VA + +A
Sbjct: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
Query: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLK 393
+ +++ ++ + + IY+T+LG D KTK +S YLK
Sbjct: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
Score = 32.3 bits (72), Expect = 1.3
Identities = 23/80 (28%), Positives = 35/80 (43%)
Query: 309 KRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEI 368
++G KE L AL + V G H + L LA L G Y E Q+A+ +
Sbjct: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
Query: 369 YQTKLGPDDPNVAKTKNNLA 388
+ +G + PN + +LA
Sbjct: 1050 SERVMGTEHPNTIQEYMHLA 1069
>gi|18104962 amyloid beta precursor protein-binding protein 2 [Homo
sapiens]
Length = 585
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/231 (24%), Positives = 109/231 (47%), Gaps = 18/231 (7%)
Query: 220 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 268
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
Query: 269 NKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 328
++A +L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
Query: 329 KVLGKDHPDVAKQLNNLALLCQ-NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNL 387
++LG++ +VA + +LA L + +YE E Y R++ I + G + L
Sbjct: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
Query: 388 ASCYLKQGKFKQAETLYKEILT---RAHEREFGSVDDENKPIWMHAEEREE 435
Y G +++ Y +L+ R +R++ SV D + + + EE
Sbjct: 521 IKLYNSIGNYEKVFE-YHNVLSNWNRLRDRQY-SVTDALEDVSTSPQSTEE 569
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/286 (23%), Positives = 112/286 (39%), Gaps = 19/286 (6%)
Query: 228 RYEVAVPLCKQALEDLEKTSGH-DHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
+Y + K A ++K S H + A + L + ++ Y +A +A+ +E
Sbjct: 178 KYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAM--KE 235
Query: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
T G V L + + ++K+AE L K A+ + G HP + L +
Sbjct: 236 ITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYG 295
Query: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLA-SCYLKQ---GKFKQA-- 400
N + YQ AL+I Q+ G + +VA +LA S Y+ Q GKF A
Sbjct: 296 FYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALF 355
Query: 401 ----------ETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYG 450
L ++ L A + ++ E I H +E E+ ++
Sbjct: 356 HAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQ 415
Query: 451 GWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQ 496
KA + NLG LY+ KF+ AE + A++ ++Q
Sbjct: 416 LAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQ 461
>gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]
Length = 501
Score = 56.2 bits (134), Expect = 9e-08
Identities = 37/146 (25%), Positives = 77/146 (52%), Gaps = 9/146 (6%)
Query: 268 QNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKYKEAEPLCKRALE 325
+ K + L D +++ EK H + L+ A +L+ K+ +A+ + ++AL+
Sbjct: 331 EEKIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS--QAQRMYEKALQ 386
Query: 326 IREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKN 385
I E++ G+ HP +++LA QG+++E Y QRA ++ + + P + +
Sbjct: 387 ISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQ---INHPELHMVLS 443
Query: 386 NLASCYLKQGKFKQAETLYKEILTRA 411
NLA+ + + ++ QA+ +Y+E L +A
Sbjct: 444 NLAAVLMHRERYTQAKEIYQEALKQA 469
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 53.1 bits (126), Expect = 7e-07
Identities = 47/157 (29%), Positives = 68/157 (43%), Gaps = 24/157 (15%)
Query: 252 PDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 311
P+ A + LA VY +Q A + A+ ++ P NLA ++G
Sbjct: 246 PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------PHFPDAYCNLANALKEKG 297
Query: 312 KYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQT 371
EAE AL + P A LNNLA + + QG EE Y++ALE++
Sbjct: 298 SVAEAEDCYNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF-- 347
Query: 372 KLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 408
P A +NLAS +QGK ++A YKE +
Sbjct: 348 ------PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 378
Score = 51.2 bits (121), Expect = 3e-06
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 24/154 (15%)
Query: 218 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANL 277
NL Y QG ++A+ ++A+E P LA +++ +A +
Sbjct: 254 NLACVYYEQGLIDLAIDTYRRAIEL--------QPHFPDAYCNLANALKEKGSVAEAEDC 305
Query: 278 LNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPD 337
N AL + P A +LNNLA + ++G +EA L ++ALE+ P+
Sbjct: 306 YNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEV--------FPE 349
Query: 338 VAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQT 371
A +NLA + Q QGK +E +Y+ A+ I T
Sbjct: 350 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 383
Score = 38.1 bits (87), Expect = 0.024
Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 269
P +L+NL QG E AV L ++ALE P+ A + LA V + Q
Sbjct: 314 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQG 365
Query: 270 KYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 329
K ++A +A+ I P A +N+ + + A RA++I
Sbjct: 366 KLQEALMHYKEAIRI--------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI--- 414
Query: 330 VLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLAS 389
+P A +NLA + ++ G E Y+ AL KL PD P+ NLA
Sbjct: 415 -----NPAFADAHSNLASIHKDSGNIPEAIASYRTAL-----KLKPDFPD---AYCNLAH 461
Query: 390 C 390
C
Sbjct: 462 C 462
Score = 32.3 bits (72), Expect = 1.3
Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 16/114 (14%)
Query: 291 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQ 350
K +P +A +NL +Y +RG+ +EA + AL ++ PD NLA
Sbjct: 73 KQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLK--------PDFIDGYINLAAALV 124
Query: 351 NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLY 404
G E Y AL+ +P++ +++L + G+ ++A+ Y
Sbjct: 125 AAGDMEGAVQAYVSALQY--------NPDLYCVRSDLGNLLKALGRLEEAKACY 170
Score = 32.0 bits (71), Expect = 1.7
Identities = 53/213 (24%), Positives = 75/213 (35%), Gaps = 34/213 (15%)
Query: 287 KTLGKDHPAVAATLN------NLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAK 340
K LG+ A A L N AV + G A+ A+ EK + D P+
Sbjct: 158 KALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLD-PNFLD 216
Query: 341 QLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQA 400
NL + + ++ Y RAL + PN A NLA Y +QG A
Sbjct: 217 AYINLGNVLKEARIFDRAVAAYLRALSL--------SPNHAVVHGNLACVYYEQGLIDLA 268
Query: 401 ETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGE--YGGWYKACKV 458
Y+ + E +P + A K+K + E Y + C
Sbjct: 269 IDTYRRAI-------------ELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLC-- 313
Query: 459 DSPTVTTTLKNLGALYRRQGKFEAAETLEEAAM 491
PT +L NL + R QG E A L A+
Sbjct: 314 --PTHADSLNNLANIKREQGNIEEAVRLYRKAL 344
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 53.1 bits (126), Expect = 7e-07
Identities = 47/157 (29%), Positives = 68/157 (43%), Gaps = 24/157 (15%)
Query: 252 PDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 311
P+ A + LA VY +Q A + A+ ++ P NLA ++G
Sbjct: 256 PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------PHFPDAYCNLANALKEKG 307
Query: 312 KYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQT 371
EAE AL + P A LNNLA + + QG EE Y++ALE++
Sbjct: 308 SVAEAEDCYNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF-- 357
Query: 372 KLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 408
P A +NLAS +QGK ++A YKE +
Sbjct: 358 ------PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 388
Score = 51.2 bits (121), Expect = 3e-06
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 24/154 (15%)
Query: 218 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANL 277
NL Y QG ++A+ ++A+E P LA +++ +A +
Sbjct: 264 NLACVYYEQGLIDLAIDTYRRAIEL--------QPHFPDAYCNLANALKEKGSVAEAEDC 315
Query: 278 LNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPD 337
N AL + P A +LNNLA + ++G +EA L ++ALE+ P+
Sbjct: 316 YNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEV--------FPE 359
Query: 338 VAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQT 371
A +NLA + Q QGK +E +Y+ A+ I T
Sbjct: 360 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 393
Score = 38.1 bits (87), Expect = 0.024
Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 269
P +L+NL QG E AV L ++ALE P+ A + LA V + Q
Sbjct: 324 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQG 375
Query: 270 KYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 329
K ++A +A+ I P A +N+ + + A RA++I
Sbjct: 376 KLQEALMHYKEAIRI--------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI--- 424
Query: 330 VLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLAS 389
+P A +NLA + ++ G E Y+ AL KL PD P+ NLA
Sbjct: 425 -----NPAFADAHSNLASIHKDSGNIPEAIASYRTAL-----KLKPDFPD---AYCNLAH 471
Query: 390 C 390
C
Sbjct: 472 C 472
Score = 32.3 bits (72), Expect = 1.3
Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 16/114 (14%)
Query: 291 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQ 350
K +P +A +NL +Y +RG+ +EA + AL ++ PD NLA
Sbjct: 83 KQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLK--------PDFIDGYINLAAALV 134
Query: 351 NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLY 404
G E Y AL+ +P++ +++L + G+ ++A+ Y
Sbjct: 135 AAGDMEGAVQAYVSALQY--------NPDLYCVRSDLGNLLKALGRLEEAKACY 180
Score = 32.0 bits (71), Expect = 1.7
Identities = 53/213 (24%), Positives = 75/213 (35%), Gaps = 34/213 (15%)
Query: 287 KTLGKDHPAVAATLN------NLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAK 340
K LG+ A A L N AV + G A+ A+ EK + D P+
Sbjct: 168 KALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLD-PNFLD 226
Query: 341 QLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQA 400
NL + + ++ Y RAL + PN A NLA Y +QG A
Sbjct: 227 AYINLGNVLKEARIFDRAVAAYLRALSL--------SPNHAVVHGNLACVYYEQGLIDLA 278
Query: 401 ETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGE--YGGWYKACKV 458
Y+ + E +P + A K+K + E Y + C
Sbjct: 279 IDTYRRAI-------------ELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLC-- 323
Query: 459 DSPTVTTTLKNLGALYRRQGKFEAAETLEEAAM 491
PT +L NL + R QG E A L A+
Sbjct: 324 --PTHADSLNNLANIKREQGNIEEAVRLYRKAL 354
>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
sapiens]
Length = 796
Score = 50.1 bits (118), Expect = 6e-06
Identities = 47/185 (25%), Positives = 89/185 (48%), Gaps = 9/185 (4%)
Query: 11 IKEDKLE--KLTQDEIISKTKQ--VIQGLEALKNEHNSILQSLLETLKC--LKKDDESNL 64
+KE +LE +L + E ++KT+Q ++Q +E +K+E ++ +L E+ + + + N+
Sbjct: 569 LKESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIENI 628
Query: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
+S L+ ++ SEA + N L+ + E + L V +NQ L++EL
Sbjct: 629 QTYQSTAEENFLQEIKNAKSEASIY---KNSLSEIGKECEMLSKMVMETKTDNQILKEEL 685
Query: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDE 184
Q+ K E S+++L E+K LE + + + D E + L D N
Sbjct: 686 KKHSQENIKFENSISRLTEDKILLENYVRSIENERDTLEFEMRHLQREYLSLSDKICNQH 745
Query: 185 DDPGQ 189
+DP +
Sbjct: 746 NDPSK 750
Score = 37.0 bits (84), Expect = 0.054
Identities = 37/174 (21%), Positives = 82/174 (47%), Gaps = 20/174 (11%)
Query: 12 KEDKLEKLTQDEIISKTKQVIQGLEALKNEHN--SILQSLLETLKCLKKDDESNLVEEKS 69
K+ +E L D++ SK + + + NE+N SI ++T L DE ++E+K+
Sbjct: 499 KQQMMEAL--DQLKSKEHKTQSDMAIVNNENNRMSIEMEAMKT-NILLIQDEKEMLEKKT 555
Query: 70 NMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQ 129
+ + K L L E+Q+ + ++ +++ + + L Q + ++DE N +
Sbjct: 556 HQLLKEKSSLGNELKESQL------EIIQLKEKERLAKTEQETLLQIIETVKDEKLNLET 609
Query: 130 KLQKSEQSVAQLEEEKKHLE---------FMNQLKKYDDDISPSEDKDTDSTKE 174
LQ+S + +E E ++++ F+ ++K + S ++ ++ KE
Sbjct: 610 TLQESTAARQIMEREIENIQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKE 663
Score = 32.3 bits (72), Expect = 1.3
Identities = 24/110 (21%), Positives = 50/110 (45%), Gaps = 1/110 (0%)
Query: 47 QSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKL 106
QSL++ ++ +K + NLVEEKS + K + E + + + N ++ + + L
Sbjct: 430 QSLIQKVETYEKQLK-NLVEEKSTIQSKLSKTEEYSKECLKEFKKIISKYNVLQGQNKTL 488
Query: 107 RAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKK 156
+ +L E Q + + L + K K++ +A + E + + K
Sbjct: 489 EEKNIQLSLEKQQMMEALDQLKSKEHKTQSDMAIVNNENNRMSIEMEAMK 538
>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
sapiens]
Length = 833
Score = 50.1 bits (118), Expect = 6e-06
Identities = 47/185 (25%), Positives = 89/185 (48%), Gaps = 9/185 (4%)
Query: 11 IKEDKLE--KLTQDEIISKTKQ--VIQGLEALKNEHNSILQSLLETLKC--LKKDDESNL 64
+KE +LE +L + E ++KT+Q ++Q +E +K+E ++ +L E+ + + + N+
Sbjct: 606 LKESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIENI 665
Query: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
+S L+ ++ SEA + N L+ + E + L V +NQ L++EL
Sbjct: 666 QTYQSTAEENFLQEIKNAKSEASIY---KNSLSEIGKECEMLSKMVMETKTDNQILKEEL 722
Query: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDE 184
Q+ K E S+++L E+K LE + + + D E + L D N
Sbjct: 723 KKHSQENIKFENSISRLTEDKILLENYVRSIENERDTLEFEMRHLQREYLSLSDKICNQH 782
Query: 185 DDPGQ 189
+DP +
Sbjct: 783 NDPSK 787
Score = 37.0 bits (84), Expect = 0.054
Identities = 37/174 (21%), Positives = 82/174 (47%), Gaps = 20/174 (11%)
Query: 12 KEDKLEKLTQDEIISKTKQVIQGLEALKNEHN--SILQSLLETLKCLKKDDESNLVEEKS 69
K+ +E L D++ SK + + + NE+N SI ++T L DE ++E+K+
Sbjct: 536 KQQMMEAL--DQLKSKEHKTQSDMAIVNNENNRMSIEMEAMKT-NILLIQDEKEMLEKKT 592
Query: 70 NMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQ 129
+ + K L L E+Q+ + ++ +++ + + L Q + ++DE N +
Sbjct: 593 HQLLKEKSSLGNELKESQL------EIIQLKEKERLAKTEQETLLQIIETVKDEKLNLET 646
Query: 130 KLQKSEQSVAQLEEEKKHLE---------FMNQLKKYDDDISPSEDKDTDSTKE 174
LQ+S + +E E ++++ F+ ++K + S ++ ++ KE
Sbjct: 647 TLQESTAARQIMEREIENIQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKE 700
Score = 32.3 bits (72), Expect = 1.3
Identities = 24/110 (21%), Positives = 50/110 (45%), Gaps = 1/110 (0%)
Query: 47 QSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKL 106
QSL++ ++ +K + NLVEEKS + K + E + + + N ++ + + L
Sbjct: 467 QSLIQKVETYEKQLK-NLVEEKSTIQSKLSKTEEYSKECLKEFKKIISKYNVLQGQNKTL 525
Query: 107 RAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKK 156
+ +L E Q + + L + K K++ +A + E + + K
Sbjct: 526 EEKNIQLSLEKQQMMEALDQLKSKEHKTQSDMAIVNNENNRMSIEMEAMK 575
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 49.7 bits (117), Expect = 8e-06
Identities = 89/451 (19%), Positives = 191/451 (42%), Gaps = 52/451 (11%)
Query: 1 MYDNMSTMVYIKEDKLEKLTQ----------DEIISKTKQVIQGLEAL--KNEHNSILQS 48
+ +N+S + +KE LEK Q +E +S + + + + L K E ++L S
Sbjct: 789 LQENLSEVSQVKET-LEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSS 847
Query: 49 LLETL---------KCLKKDD-ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNA 98
LE L K +KD+ E L++ K + E++++ + + +++ L
Sbjct: 848 DLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRL 907
Query: 99 VESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQL-EEEKKHLE-FMNQLKK 156
E + ++L+ ++ + + +L+ + + K ++S+Q A+ EEEKK LE ++ L+K
Sbjct: 908 KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEK 967
Query: 157 YDD-------DISPSEDKDTDSTKEPLDDLFPN------DEDDPGQGIQQQHSSAAAAAQ 203
+ ++ ++ T TK +++ N D +D +G ++++S +
Sbjct: 968 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELE 1027
Query: 204 QGGYEI-PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILA 262
+ + A+ +Q Q E L +LED ++T+ ++ T+
Sbjct: 1028 ELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLA--SLEDTKQTNAKLQNELDTLKENNL 1085
Query: 263 LVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKR 322
+ NK K+ + N + K + A A L+ L + K AE L +
Sbjct: 1086 KNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL--QEENVKLAEELGRS 1143
Query: 323 ALEIREKVLGKDHPDVAKQLNNLALLCQNQGKY----EEVEYYYQRALEIYQTKLGPDDP 378
E+ ++ V N L + + + K+ +E + Q+++ I L D
Sbjct: 1144 RDEVTSHQKLEEERSVLN--NQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDA 1201
Query: 379 NVAKTKNNLASCYLKQGKFKQAETLYKEILT 409
+ K +N + + +G+ A++L+ + T
Sbjct: 1202 ELEKLRNEVT---VLRGENASAKSLHSVVQT 1229
Score = 30.8 bits (68), Expect = 3.9
Identities = 104/578 (17%), Positives = 220/578 (38%), Gaps = 54/578 (9%)
Query: 46 LQSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQK 105
L++ +E ++ + + NL ++ + ++ E+ A++M + N++E+ + K
Sbjct: 613 LKTQIEKMRLDYQHEIENLQNQQDS--ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSK 670
Query: 106 L-RAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEE-EKKHLEFMNQLKKYDDDISP 163
L +A+ + L E+ +T KLQ++E V +LE + K E + + +
Sbjct: 671 LDKAEDQHLV--------EMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKA 722
Query: 164 SEDKDTDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQY 223
+E+K D LD L + + + + AA Q EI + I
Sbjct: 723 TEEKLLD-----LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITR 777
Query: 224 ASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALA 283
QGR E+ + ++ L ++ + + L IL + K+ +A+
Sbjct: 778 ELQGR-ELKLTNLQENLSEVSQVK----ETLEKELQIL------KEKFAEASEEAVSVQR 826
Query: 284 IREKTLGKDHP------AVAATLNNLAV-LYGKRGKYKEAEPLCKRALEIREKVLGKDHP 336
++T+ K H +++ L L L K++E + ++ ++ +EK+
Sbjct: 827 SMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKL----EN 882
Query: 337 DVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGK 396
D+A+ + K + +R +E Q KL + N + + ++ +K +
Sbjct: 883 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQ 942
Query: 397 FKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKAC 456
+Q E + ER+ + D K + + +E K + + TS +
Sbjct: 943 SQQEAAKKHEEEKKELERK---LSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 999
Query: 457 KVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM 516
+ + T K GA G + E L + A +++ Q + + E M
Sbjct: 1000 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKA-------AQTAEDAMQIMEQM 1052
Query: 517 EKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKL 576
K ++ +++ K ++ E+ E N L +S + K
Sbjct: 1053 TKEKTETLASLEDTK-QTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKE 1111
Query: 577 VRKLKGGSSRESEP----KNPGASLAEPLFVENDSSSS 610
+ LK ++++S+ + LAE L D +S
Sbjct: 1112 IETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTS 1149
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 49.7 bits (117), Expect = 8e-06
Identities = 89/451 (19%), Positives = 191/451 (42%), Gaps = 52/451 (11%)
Query: 1 MYDNMSTMVYIKEDKLEKLTQ----------DEIISKTKQVIQGLEAL--KNEHNSILQS 48
+ +N+S + +KE LEK Q +E +S + + + + L K E ++L S
Sbjct: 824 LQENLSEVSQVKET-LEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSS 882
Query: 49 LLETL---------KCLKKDD-ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNA 98
LE L K +KD+ E L++ K + E++++ + + +++ L
Sbjct: 883 DLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRL 942
Query: 99 VESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQL-EEEKKHLE-FMNQLKK 156
E + ++L+ ++ + + +L+ + + K ++S+Q A+ EEEKK LE ++ L+K
Sbjct: 943 KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEK 1002
Query: 157 YDD-------DISPSEDKDTDSTKEPLDDLFPN------DEDDPGQGIQQQHSSAAAAAQ 203
+ ++ ++ T TK +++ N D +D +G ++++S +
Sbjct: 1003 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELE 1062
Query: 204 QGGYEI-PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILA 262
+ + A+ +Q Q E L +LED ++T+ ++ T+
Sbjct: 1063 ELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLA--SLEDTKQTNAKLQNELDTLKENNL 1120
Query: 263 LVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKR 322
+ NK K+ + N + K + A A L+ L + K AE L +
Sbjct: 1121 KNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL--QEENVKLAEELGRS 1178
Query: 323 ALEIREKVLGKDHPDVAKQLNNLALLCQNQGKY----EEVEYYYQRALEIYQTKLGPDDP 378
E+ ++ V N L + + + K+ +E + Q+++ I L D
Sbjct: 1179 RDEVTSHQKLEEERSVLN--NQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDA 1236
Query: 379 NVAKTKNNLASCYLKQGKFKQAETLYKEILT 409
+ K +N + + +G+ A++L+ + T
Sbjct: 1237 ELEKLRNEVT---VLRGENASAKSLHSVVQT 1264
Score = 30.8 bits (68), Expect = 3.9
Identities = 104/578 (17%), Positives = 220/578 (38%), Gaps = 54/578 (9%)
Query: 46 LQSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQK 105
L++ +E ++ + + NL ++ + ++ E+ A++M + N++E+ + K
Sbjct: 648 LKTQIEKMRLDYQHEIENLQNQQDS--ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSK 705
Query: 106 L-RAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEE-EKKHLEFMNQLKKYDDDISP 163
L +A+ + L E+ +T KLQ++E V +LE + K E + + +
Sbjct: 706 LDKAEDQHLV--------EMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKA 757
Query: 164 SEDKDTDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQY 223
+E+K D LD L + + + + AA Q EI + I
Sbjct: 758 TEEKLLD-----LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITR 812
Query: 224 ASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALA 283
QGR E+ + ++ L ++ + + L IL + K+ +A+
Sbjct: 813 ELQGR-ELKLTNLQENLSEVSQVK----ETLEKELQIL------KEKFAEASEEAVSVQR 861
Query: 284 IREKTLGKDHP------AVAATLNNLAV-LYGKRGKYKEAEPLCKRALEIREKVLGKDHP 336
++T+ K H +++ L L L K++E + ++ ++ +EK+
Sbjct: 862 SMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKL----EN 917
Query: 337 DVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGK 396
D+A+ + K + +R +E Q KL + N + + ++ +K +
Sbjct: 918 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQ 977
Query: 397 FKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKAC 456
+Q E + ER+ + D K + + +E K + + TS +
Sbjct: 978 SQQEAAKKHEEEKKELERK---LSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 1034
Query: 457 KVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM 516
+ + T K GA G + E L + A +++ Q + + E M
Sbjct: 1035 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKA-------AQTAEDAMQIMEQM 1087
Query: 517 EKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKL 576
K ++ +++ K ++ E+ E N L +S + K
Sbjct: 1088 TKEKTETLASLEDTK-QTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKE 1146
Query: 577 VRKLKGGSSRESEP----KNPGASLAEPLFVENDSSSS 610
+ LK ++++S+ + LAE L D +S
Sbjct: 1147 IETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTS 1184
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 49.7 bits (117), Expect = 8e-06
Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 24/165 (14%)
Query: 251 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 310
HP L L + + Q K ++A LL D++ K P A ++LA L ++
Sbjct: 436 HPQHNRALFNLGNLLKSQEKKEEAITLLKDSI--------KYGPEFADAYSSLASLLAEQ 487
Query: 311 GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQ 370
++KEAE + + + K+ PD + NN + + G E+ +YQ+A+
Sbjct: 488 ERFKEAEEIYQTGI--------KNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAI---- 535
Query: 371 TKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHERE 415
KL P +VA NL Y G+ AE YK L AH+ E
Sbjct: 536 -KLSPSH-HVAMV--NLGRLYRSLGENSMAEEWYKRALQVAHKAE 576
Score = 37.4 bits (85), Expect = 0.041
Identities = 44/207 (21%), Positives = 82/207 (39%), Gaps = 46/207 (22%)
Query: 208 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL-----------------------EDLE 244
++ + L L Y + GRYE A+ + ++A ++ E
Sbjct: 570 QVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAE 629
Query: 245 KTSGH---DHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLN 301
K + H + +L+ +Y Q + A + ++ AL ++ K P V
Sbjct: 630 KMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKD-----PKV----- 679
Query: 302 NLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYY 361
++ L+ +G + L +A E +V + +PD A+ N+ + +GKY Y
Sbjct: 680 -ISELFFTKGNQLREQNLLDKAFE-SYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAY 737
Query: 362 YQRALEIYQTKLGPDDPNVAKTKNNLA 388
Y+RAL++ P+ K NLA
Sbjct: 738 YERALQLV--------PDSKLLKENLA 756
Score = 33.5 bits (75), Expect = 0.60
Identities = 36/160 (22%), Positives = 64/160 (40%), Gaps = 30/160 (18%)
Query: 336 PDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQG 395
P AK N A ++QG+ +E Y+Y+ AL++Y P A NNL +
Sbjct: 372 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLY--------PRHASALNNLGTLTRDTA 423
Query: 396 KFKQAETLYKEILT--RAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWY 453
+A+ Y+ L H R ++ + + E++EE KD +G
Sbjct: 424 ---EAKMYYQRALQLHPQHNRALFNLGN----LLKSQEKKEEAITLLKDSIKYG------ 470
Query: 454 KACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRS 493
P +L +L Q +F+ AE + + +++
Sbjct: 471 -------PEFADAYSSLASLLAEQERFKEAEEIYQTGIKN 503
>gi|110815815 centlein isoform 1 [Homo sapiens]
Length = 1406
Score = 49.3 bits (116), Expect = 1e-05
Identities = 60/286 (20%), Positives = 125/286 (43%), Gaps = 33/286 (11%)
Query: 18 KLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETL-KCLKKDDESNLVE-------EKS 69
K E++ + + + L+ LK H SI ++ ++ L +C+ + E L ++S
Sbjct: 619 KRENQELMIQKMNLEEELDELK-VHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRS 677
Query: 70 NMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQ 129
+ EMLE L Q + L N L + E +KL+ ++L +EN +L+ L Q+
Sbjct: 678 TPEKNGKEMLEQTL---QKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQE 734
Query: 130 KLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLD-DLFPNDEDDPG 188
+ E+ + Q+ + K +E N + IS E + T ++ + + N+ ++
Sbjct: 735 DTETREKELEQIIKGSKDVEKEN--TELQVKISELETEVTSLRRQVAEANALRNENEELI 792
Query: 189 QGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEK--T 246
+++ H SA A + + GRY+ + K + +K +
Sbjct: 793 NPMEKSHQSADRAKSE--------------MATMKVRSGRYDCKTTMTKVKFKAAKKNCS 838
Query: 247 SGHDHPDVATMLNILALVYRDQNK--YKDAANLLNDALAIREKTLG 290
G H + + +++ V+ + +K ++D + +D+ A +TLG
Sbjct: 839 VGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLG 884
Score = 31.2 bits (69), Expect = 3.0
Identities = 38/156 (24%), Positives = 63/156 (40%), Gaps = 19/156 (12%)
Query: 32 IQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMA 91
+ LE L S ++ L E LK + N+ K + + E E V +
Sbjct: 454 LSSLETLMVSQKSEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRS 513
Query: 92 --LSNHLNAVESEK-QKLRAQVRRL----------CQENQWLRDELANTQQKLQKSEQSV 138
LS + +SE+ QKLR R++ QEN LRD +++LQ + +
Sbjct: 514 RSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNY 573
Query: 139 AQLEEEKKHLE------FMNQLKKYDDDISPSEDKD 168
++E+ K E + ++K+ D ED D
Sbjct: 574 RAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSD 609
Score = 30.4 bits (67), Expect = 5.0
Identities = 40/155 (25%), Positives = 75/155 (48%), Gaps = 19/155 (12%)
Query: 15 KLEKLTQDE-IISKTKQVIQGLEALKNE------HNSILQSLLETLKCLKKDDE---SNL 64
+LE ++ +E ++++T+ + + L +LK E + SL + L+ D S +
Sbjct: 88 RLEGISVEEAMVTRTQLLEEELSSLKEELALCQADKEFVWSLWKRLQVTNPDLTQVVSLV 147
Query: 65 VE-EKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESE-KQKLRAQVRR---LCQENQW 119
VE EK K ++LE+ QV A ES KQ++ V+R + +EN +
Sbjct: 148 VEREKQKSEAKDRKVLEI----LQVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAF 203
Query: 120 LRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQL 154
LR E ++ ++K + Q + +E ++ E N+L
Sbjct: 204 LRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRL 238
Score = 30.4 bits (67), Expect = 5.0
Identities = 20/97 (20%), Positives = 48/97 (49%), Gaps = 4/97 (4%)
Query: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
V+E++ +RK LE + + + V++++++ R ++ L +EN+ L
Sbjct: 197 VDEENAFLRKEFSDLEKKFKDKS--QEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRC 254
Query: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDI 161
+ L+K + A L +EK + ++K ++D++
Sbjct: 255 TDLLNDLEKLRKQEAHLRKEKYSTD--AKIKTFEDNL 289
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 47.8 bits (112), Expect = 3e-05
Identities = 46/191 (24%), Positives = 79/191 (41%), Gaps = 33/191 (17%)
Query: 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 269
P + + N Y +G Y LC++A+E + + + D+ +A + Y +
Sbjct: 256 PTNMTYITNQAAVYFEKGDYNKCRELCEKAIE-VGRENREDYRQIAKAYARIGNSYFKEE 314
Query: 270 KYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 329
KYKDA + N +LA P V K ++AE + K ++
Sbjct: 315 KYKDAIHFYNKSLAEHRT------PDVLK-------------KCQQAEKILK-----EQE 350
Query: 330 VLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLAS 389
L +PD+A + N C +G Y + +Y A++ +P AK +N A+
Sbjct: 351 RLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIK--------RNPKDAKLYSNRAA 402
Query: 390 CYLKQGKFKQA 400
CY K +F+ A
Sbjct: 403 CYTKLLEFQLA 413
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/171 (21%), Positives = 71/171 (41%), Gaps = 41/171 (23%)
Query: 279 NDALAIREKTLGKD--------------------HPAVAATLNNLAVLYGKRGKYKEAEP 318
N A++EK LG D P + N A +Y ++G Y +
Sbjct: 221 NKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRE 280
Query: 319 LCKRALEI-REKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQT------ 371
LC++A+E+ RE +D+ +AK + + KY++ ++Y ++L ++T
Sbjct: 281 LCEKAIEVGREN--REDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKK 338
Query: 372 ------------KLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTR 410
+L +P++A + N + ++G + QA Y E + R
Sbjct: 339 CQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKR 389
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 47.4 bits (111), Expect = 4e-05
Identities = 109/585 (18%), Positives = 229/585 (39%), Gaps = 64/585 (10%)
Query: 7 TMVYIKEDKLEKL-TQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLV 65
T V + ED+L +L TQ ++ ++ +Q ++ L+ EH L + + L++ E
Sbjct: 228 TQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ--ELTAA 285
Query: 66 EEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELA 125
E+++ ++ + L+ +E + + + + + EK +L R+L N L++E+
Sbjct: 286 EQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHN--LQEEMH 343
Query: 126 NTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDED 185
+ ++ +++ Q+ A+LE LE Q K + + S T + L +D
Sbjct: 344 HLLEQFEQAGQAQAELESRYSALE---QKHKAEMEEKTSHILSLQKTGQELQSACDALKD 400
Query: 186 DPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEK 245
+ +Q ++ A +AQ T+ L Q + + E++ L + L+ E
Sbjct: 401 QNSKLLQDKNEQAVQSAQ-----------TIQQLEDQLQQKSK-EISQFLNRLPLQQHET 448
Query: 246 TSGHDHPDV-------ATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAA 298
S PDV T NI +L R + LL ++ + E + +
Sbjct: 449 ASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI 508
Query: 299 TLNNLAVLYGKRGKYKE-------AEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQN 351
TL G+ + A A E + VL K+L+ LL +
Sbjct: 509 TLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELS--VLLLEM 566
Query: 352 QGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRA 411
+ EE+ + L++ + D V K +KQ + + + ++
Sbjct: 567 KEAQEEIAFL---KLQLQGKRAEEADHEVLDQKE------MKQMEGEGIAPIKMKVFLED 617
Query: 412 HEREFGSVDDENKPIWMHAEEREECKGKQKDGT----SFGEYGGWYKACKVDSPTVTTTL 467
++F + +E + A E+E+ + + T S + G K+ K D + +
Sbjct: 618 TGQDFPLMPNEESS--LPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAV 675
Query: 468 KNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNV 527
++G ++ + + ++ LE N HK A+ + + EK + +LN
Sbjct: 676 PDIGQCHQDELERLKSQILELEL---------NFHK---AQEIYEKNLDEKAKEISNLNQ 723
Query: 528 DVVKYESGPDGGEEVSMSVEWNGDG-TGSLKRSGSFSKLRASIRR 571
+ +++ D ++ D +K ++LRA +++
Sbjct: 724 LIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQ 768
Score = 37.0 bits (84), Expect = 0.054
Identities = 38/184 (20%), Positives = 78/184 (42%), Gaps = 29/184 (15%)
Query: 12 KEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSNM 71
KE ++ + + + ++ +++ +EA++ E + L T + KK+ E L E + M
Sbjct: 1613 KEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRST-EANKKETEKQLQEAEQEM 1671
Query: 72 IRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVR-----------RLCQENQWL 120
+M + S+ Q ++ L E E +LRA+V L N +
Sbjct: 1672 EEMKEKMRKFAKSKQQKILEL-------EEENDRLRAEVHPAGDTAKECMETLLSSNASM 1724
Query: 121 RDELANTQ----------QKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTD 170
++EL + Q L + S+++ ++ KH N K+ + + + D T+
Sbjct: 1725 KEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTN 1784
Query: 171 STKE 174
T+E
Sbjct: 1785 VTEE 1788
Score = 35.8 bits (81), Expect = 0.12
Identities = 36/129 (27%), Positives = 60/129 (46%), Gaps = 13/129 (10%)
Query: 38 LKNEHNSILQSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLN 97
L + + + L + LK LKK+ +SN KS M +K E LE L +A+ HL
Sbjct: 2084 LDDTQSEAARVLADNLK-LKKELQSNKESVKSQMKQKD-EDLERRLEQAE-----EKHLK 2136
Query: 98 AVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKY 157
EK+ ++ ++ L +E L + + Q L K ++ V QL+E + QL +
Sbjct: 2137 ----EKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLD--STVTQLAAF 2190
Query: 158 DDDISPSED 166
+S +D
Sbjct: 2191 TKSMSSLQD 2199
Score = 32.0 bits (71), Expect = 1.7
Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 16/150 (10%)
Query: 9 VYIKEDKLEKLTQDEIISKTKQVIQGLEALKN--EHNSILQSLLETLKCLKKDDESNLVE 66
V ++ + L K Q ++S+ + + ++ LK+ E N Q+ LE + K D+++N+ E
Sbjct: 1731 VKMEYETLSKKFQS-LMSEKDSLSEEVQDLKHQIEGNVSKQANLEATE--KHDNQTNVTE 1787
Query: 67 EKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELAN 126
E + I G +E Q +++S ES A ++ DE+ N
Sbjct: 1788 EGTQSIP--------GETEEQDSLSMSTRPTCSESVPSAKSANPA--VSKDFSSHDEINN 1837
Query: 127 TQQKLQKSEQSVAQLEEEK-KHLEFMNQLK 155
Q++ + ++ +A LEEEK K+ EF L+
Sbjct: 1838 YLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1867
Score = 32.0 bits (71), Expect = 1.7
Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 2/137 (1%)
Query: 26 SKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSE 85
+K K+ I+GL + ++ NS + L+ ++D + ++ K + ++ LE+ E
Sbjct: 2506 NKLKEEIRGLRSHMDDLNSE-NAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKE 2564
Query: 86 AQVMMA-LSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEE 144
+ A L L E + LR L +E Q L E+ + + + + + V L+EE
Sbjct: 2565 LENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2624
Query: 145 KKHLEFMNQLKKYDDDI 161
+ QLK ++++
Sbjct: 2625 GTLGLYHAQLKVKEEEV 2641
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 47.4 bits (111), Expect = 4e-05
Identities = 45/161 (27%), Positives = 81/161 (50%), Gaps = 12/161 (7%)
Query: 7 TMVYIKEDKLEKLTQDEIISKTKQVI----QGLEALKNEHNSIL---QSLLETLKCLKKD 59
T V + E+KLE +I + K I Q LE K E + ++L ++CL K+
Sbjct: 1729 TQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKE 1788
Query: 60 DESNLVEEKSNMIRKSLEMLE--LGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQEN 117
E ++EK ++ K L + L +E M SN L +E +KL+ ++ +L ++
Sbjct: 1789 KED--LQEKCDIWEKKLAQTKRVLAAAEENSKMEQSN-LEKLELNVRKLQQELDQLNRDK 1845
Query: 118 QWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYD 158
L ++++ QQ+LQ+ ++V L+EE +++ L K D
Sbjct: 1846 LSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQD 1886
Score = 38.5 bits (88), Expect = 0.018
Identities = 38/157 (24%), Positives = 80/157 (50%), Gaps = 23/157 (14%)
Query: 29 KQVIQGLEALKNEHNSILQSLLETLK---CLKKDDES-NLV----EEKSNMIRKSLEMLE 80
KQV EALK + + + ++LLE + C++K+ + LV E++ + K L ++
Sbjct: 2071 KQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQ 2130
Query: 81 LGLSEAQVMMA-----------LSNHLNAVESE-KQKLRAQVRRLCQENQWLRDELANTQ 128
+E + MA +S+ + ++SE K ++R ++ L NQ+L + A+ +
Sbjct: 2131 YEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNL---NQFLPELPADLE 2187
Query: 129 QKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSE 165
L+++E +LE K++L F +++ ++ S+
Sbjct: 2188 AILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQ 2224
Score = 37.7 bits (86), Expect = 0.032
Identities = 128/618 (20%), Positives = 237/618 (38%), Gaps = 92/618 (14%)
Query: 13 EDKLEKLTQDEIISKTKQV------IQGLEALKNEHNSIL------QSLLETLKCLKKDD 60
E ++EK Q EI K K++ I L++ +H+ + + L+ + +
Sbjct: 516 ELQMEKQKQ-EIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQL 574
Query: 61 ESNLVEEKSNMIRKSLEM--LELGLSEAQVMM--ALSNHLNAVESEKQK----LRAQVRR 112
ES L E S + +++ E+ LE L+E Q+ AL L V S Q+ ++ Q +
Sbjct: 575 ESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQ 634
Query: 113 LCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDST 172
E + LRDE Q+L + EQ QLE E M + + + + S
Sbjct: 635 AQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASL 694
Query: 173 KEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVA 232
++ DL + + ++ + + A A Q E+ R + Q A Q E
Sbjct: 695 QQTQGDLSAYEAE-----LEARLNLRDAEANQLKEELEKVTRLTQ--LEQSALQAELEKE 747
Query: 233 VPLCKQAL------EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
K AL E+ E+ + H + + + L+ + +++ N + D L E
Sbjct: 748 RQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPE 807
Query: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
+ VAA ++ L R K K + + VLGK D+ KQ +
Sbjct: 808 E--------VAARVDEL------RRKLKLGTG--EMNIHSPSDVLGKSLADLQKQFSE-- 849
Query: 347 LLCQNQGKYEEV---EYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETL 403
+L +++ + +E E Q + + Q KL + + K +Q E
Sbjct: 850 ILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDK-RQHEAR 908
Query: 404 YKEILTRAH----------------EREFGSVDDENKPIWMHAEEREECKGKQKDGTSFG 447
+++ H + + D+E + I E E+ K K +D S
Sbjct: 909 IQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEK-KKKLEDAKSQE 967
Query: 448 EYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAE-TLEEAAMRSRKQGLDNVHKQRV 506
+ G K K V T+ K AE T+ + ++S + ++++R
Sbjct: 968 QVFGLDKELKKLKKAVATS-----------DKLATAELTIAKDQLKSLHGTVMKINQER- 1015
Query: 507 AEVLNDPENMEKRRSRESLNVDVVKYESG------PDGGEEVSMSVEWNGDGTGSLKRSG 560
AE L + E ++ ++ + ++ + E GE+ + +E G GTG+ +
Sbjct: 1016 AEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEKTGVGTGANSQVL 1075
Query: 561 SFSKLRASIRRSSEKLVR 578
KL ++ R ++ R
Sbjct: 1076 EIEKLNETMERQRTEIAR 1093
Score = 36.2 bits (82), Expect = 0.092
Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 4/135 (2%)
Query: 11 IKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSN 70
+K D+ + Q + + I+ E LK E N I+ + +CL K E + E+
Sbjct: 1492 VKADQQLRSLQADAKDLEQHKIKQEEILK-EINKIVAAKDSDFQCLSKKKEK--LTEELQ 1548
Query: 71 MIRKSLEMLELGLSE-AQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQ 129
++K +EM E QV+ L A +E +KL++QV QE L +L + ++
Sbjct: 1549 KLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKE 1608
Query: 130 KLQKSEQSVAQLEEE 144
+L + S+ Q + +
Sbjct: 1609 ELHLLQGSMVQAKAD 1623
Score = 33.1 bits (74), Expect = 0.78
Identities = 38/164 (23%), Positives = 68/164 (41%), Gaps = 24/164 (14%)
Query: 12 KEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSNM 71
KE +K D+++SK + + L+ E +SL +TL K+ L E + +
Sbjct: 1980 KELTDQKSKLDQVLSKVLAAEERVRTLQEEERWC-ESLEKTLSQTKRQ----LSEREQQL 2034
Query: 72 IRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLC----------------- 114
+ KS E+L L + S N +E++K QV L
Sbjct: 2035 VEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQ 2094
Query: 115 -QENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEF-MNQLKK 156
QEN ++ E+A + Q + + +L +E +++ +LKK
Sbjct: 2095 KQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKK 2138
Score = 31.6 bits (70), Expect = 2.3
Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 34/179 (18%)
Query: 8 MVYIKEDKLEKLT------QDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDE 61
++ K +LEKL Q E+ +Q+ E L S++Q+ + + L+ +
Sbjct: 1574 LLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGET 1633
Query: 62 SNLVEEKSNMIRKSLEMLE----------LGLSEAQVMMALSNHLNAVESEKQKLRAQVR 111
V EK N IR+ +LE + +SE + + L +E E++ L+ +R
Sbjct: 1634 E--VTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQ--EIEKEEENLQVVLR 1689
Query: 112 RLCQENQWLR---DELANTQQKLQ----KSEQSVAQLE-------EEKKHLEFMNQLKK 156
++ + L+ D L +LQ + +Q V++LE EEK LE + Q+ +
Sbjct: 1690 QMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQ 1748
Score = 30.8 bits (68), Expect = 3.9
Identities = 15/58 (25%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 92 LSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLE 149
L N ++ +E Q L+++ R E +W+R +++++++ ++ L +EKK LE
Sbjct: 1321 LENEVSRLEDIMQHLKSKKR----EERWMRASKRQSEKEMEELHHNIDDLLQEKKSLE 1374
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 46.6 bits (109), Expect = 7e-05
Identities = 51/232 (21%), Positives = 100/232 (43%), Gaps = 18/232 (7%)
Query: 23 EIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLE-- 80
++++ K ++Q + LK E Q +LE LKC + D ES L+E+ + E+ +
Sbjct: 835 KLVNLEKDLVQQKDILKKEVQEE-QEILECLKC-EHDKESRLLEKHDESVTDVTEVPQDF 892
Query: 81 ---------LGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKL 131
L E Q+ L NHL + EKQ+ L + L + L ++++
Sbjct: 893 EKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQR---AFEILDRGPLSLDNTLYQVEKEM 949
Query: 132 QKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDEDDPGQGI 191
++ E+ +AQ + L+ + ++ +I+ E+K KE L+ + + +
Sbjct: 950 EEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERAL 1009
Query: 192 Q--QQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALE 241
++ SA G EI + + L +L Q + ++ ++ALE
Sbjct: 1010 ARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALE 1061
Score = 33.1 bits (74), Expect = 0.78
Identities = 29/135 (21%), Positives = 70/135 (51%), Gaps = 21/135 (15%)
Query: 29 KQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL--VEEKSNMIRKSLEMLELGLSEA 86
+Q + LE L+++ + L+E ++ +K D++ L ++++ RK E+++L + +
Sbjct: 600 RQQREELEKLESK-----RKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQ 654
Query: 87 QVMMA-----LSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQL 141
+ + + N L + +EK+K E + LR++ QK ++ E++ ++
Sbjct: 655 EESLKRRSFHIENKLKDLLAEKEKF---------EEERLREQQEIELQKKRQEEETFLRV 705
Query: 142 EEEKKHLEFMNQLKK 156
+EE + L+ +N +K
Sbjct: 706 QEELQRLKELNNNEK 720
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 46.2 bits (108), Expect = 9e-05
Identities = 56/226 (24%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 204 QGGYEIPARLRTLHNLVIQ----YASQGR--------------YEVAVPLCKQALEDLEK 245
+G Y+ +L H + Q YA+QGR Y+ AV +Q L+ +
Sbjct: 487 KGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISME 546
Query: 246 TSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAV 305
+ D A+ LA+ Y+ + A + L I + +D + A L+NL
Sbjct: 547 VN--DRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIAREL--RDIQSEARALSNLGN 602
Query: 306 LYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRA 365
+ RG+Y +A P ++ L + + +D K +NL G Y+E YY++
Sbjct: 603 FHCSRGEYVQAAPYYEQYLRLAPDL--QDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQD 660
Query: 366 LEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRA 411
L + K D + AK NL + F +AE K +L+ A
Sbjct: 661 LAL--AKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLA 704
Score = 44.3 bits (103), Expect = 3e-04
Identities = 47/187 (25%), Positives = 77/187 (41%), Gaps = 7/187 (3%)
Query: 228 RYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREK 287
+Y+ A+ Q LE ++ S D P LA VY KY A + L + +K
Sbjct: 769 KYDKALGYHTQELEVYQELS--DLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQK 826
Query: 288 TLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHP-DVAKQLNNLA 346
KD A N+ + +EA ++ L + +++ G + D + NL
Sbjct: 827 L--KDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLG 884
Query: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKE 406
+ G YEE YY++ L + Q+ D AK L + + G +QA +++
Sbjct: 885 DCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQ--AKAYRGLGNGHRAMGSLQQALVCFEK 942
Query: 407 ILTRAHE 413
L AHE
Sbjct: 943 RLVVAHE 949
Score = 39.7 bits (91), Expect = 0.008
Identities = 58/256 (22%), Positives = 97/256 (37%), Gaps = 43/256 (16%)
Query: 195 HSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDV 254
H A+Q E+ + R L N+ Y + G +E AV +Q L+ + K G+ +
Sbjct: 337 HKQCVLLAKQSKDEL-SEARELGNMGAVYIAMGDFENAVQCHEQHLK-IAKDLGNKREEA 394
Query: 255 ATMLNILALVYRDQNKYKD----------AANLLNDALAIR------------------- 285
N+ + + +N K A L+ A+ +R
Sbjct: 395 RAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAK 454
Query: 286 ---EKTLG-----KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPD 337
E+ LG KD A +NL +++ +G Y A L K L I +++ D+
Sbjct: 455 QYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQEL--SDYAA 512
Query: 338 VAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKF 397
+ N+ G Y++ Y+++ L+I D + A T NLA Y G
Sbjct: 513 QGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEV--NDRASQASTHGNLAVAYQALGAH 570
Query: 398 KQAETLYKEILTRAHE 413
+A Y+ L A E
Sbjct: 571 DRALQHYQNHLNIARE 586
Score = 39.7 bits (91), Expect = 0.008
Identities = 55/236 (23%), Positives = 93/236 (39%), Gaps = 38/236 (16%)
Query: 208 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL------EDLEKTS------GHDHPDVA 255
+I + R L NL + S+G Y A P +Q L +D+E G+ H +
Sbjct: 589 DIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLG 648
Query: 256 TMLNILALVYRDQNKYKDAANLLNDALAI--------------REKTLGKDHPAVAATLN 301
+ +D KD + L+ A A + + K ++A +LN
Sbjct: 649 NYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLN 708
Query: 302 NLAVLYGKRGKYKEAEPLCKR----ALEIREKVLGKDHPDVAKQLNNLALLCQNQG---- 353
N + G + +CK+ A++ E+ LG H ++L A
Sbjct: 709 NSQAKFRALGNLGDIF-ICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMI 767
Query: 354 -KYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 408
KY++ Y+ + LE+YQ D P + +LA+ Y+ GK+ A Y+E L
Sbjct: 768 QKYDKALGYHTQELEVYQEL--SDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQL 821
Score = 31.6 bits (70), Expect = 2.3
Identities = 37/156 (23%), Positives = 61/156 (39%), Gaps = 31/156 (19%)
Query: 353 GKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAH 412
G E+ Y Q+ L++ +T LG D + NL S + +G +++A T ++ L A
Sbjct: 248 GNTEKSTGYMQQDLDVAKT-LG-DQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLA- 304
Query: 413 EREFGSVDDENKPIWMHAEEREECKGKQKD----GTSFGEYGGW---YKACKV------D 459
M ++RE T+ G+Y +K C + D
Sbjct: 305 ---------------MKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKD 349
Query: 460 SPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRK 495
+ L N+GA+Y G FE A E ++ K
Sbjct: 350 ELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAK 385
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 46.2 bits (108), Expect = 9e-05
Identities = 36/164 (21%), Positives = 82/164 (50%), Gaps = 15/164 (9%)
Query: 5 MSTMVYIKEDKLEKLT---QDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDE 61
M Y KE K ++ ++EI++ TK V QG ++H++I L + K+ D+
Sbjct: 105 MVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQ 164
Query: 62 --SNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVES----------EKQKLRAQ 109
S +V+ + ++ + + + E S+ + A+S ++ +K+KL +
Sbjct: 165 LLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKE 224
Query: 110 VRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQ 153
++++ + + E+ QQ +QKS++ + +LE++ K + +N+
Sbjct: 225 LKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNE 268
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,608,424
Number of Sequences: 37866
Number of extensions: 1025097
Number of successful extensions: 6781
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 582
Number of HSP's that attempted gapping in prelim test: 4686
Number of HSP's gapped (non-prelim): 2120
length of query: 618
length of database: 18,247,518
effective HSP length: 108
effective length of query: 510
effective length of database: 14,157,990
effective search space: 7220574900
effective search space used: 7220574900
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.