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Search of human proteins with 194294540
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
(451 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 906 0.0
gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 651 0.0
gi|153791707 sorting nexin family member 30 [Homo sapiens] 381 e-106
gi|23111038 sorting nexin 2 [Homo sapiens] 106 5e-23
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 101 2e-21
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 100 5e-21
gi|4507145 sorting nexin 4 [Homo sapiens] 96 5e-20
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 94 3e-19
gi|4507143 sorting nexin 3 isoform a [Homo sapiens] 74 4e-13
gi|23111030 sorting nexin 12 [Homo sapiens] 71 2e-12
gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 67 3e-11
gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 67 3e-11
gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 67 3e-11
gi|23111047 sorting nexin 5 [Homo sapiens] 58 2e-08
gi|7657599 sorting nexin 5 [Homo sapiens] 58 2e-08
gi|23111026 sorting nexin 11 [Homo sapiens] 58 2e-08
gi|23111028 sorting nexin 11 [Homo sapiens] 58 2e-08
gi|23397574 sorting nexin 33 [Homo sapiens] 54 3e-07
gi|88703041 sorting nexin 6 isoform b [Homo sapiens] 53 6e-07
gi|23943858 sorting nexin 8 [Homo sapiens] 50 3e-06
gi|72534838 sorting nexin 6B [Homo sapiens] 50 4e-06
gi|7706706 sorting nexin 9 [Homo sapiens] 49 9e-06
gi|23111023 sorting nexin 10 [Homo sapiens] 49 1e-05
gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 44 2e-04
gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 44 2e-04
gi|23111041 sorting nexin 3 isoform b [Homo sapiens] 43 5e-04
gi|71061468 centromere protein E [Homo sapiens] 43 7e-04
gi|23238244 sorting nexin 16 isoform a [Homo sapiens] 43 7e-04
gi|23238246 sorting nexin 16 isoform a [Homo sapiens] 43 7e-04
gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1 is... 42 0.001
>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
Length = 451
Score = 906 bits (2341), Expect = 0.0
Identities = 451/451 (100%), Positives = 451/451 (100%)
Query: 1 MEGERRASQAPSSGLPAGGANGESPGGGAPFPGSSGSSALLQAEVLDLDEDEDDLEVFSK 60
MEGERRASQAPSSGLPAGGANGESPGGGAPFPGSSGSSALLQAEVLDLDEDEDDLEVFSK
Sbjct: 1 MEGERRASQAPSSGLPAGGANGESPGGGAPFPGSSGSSALLQAEVLDLDEDEDDLEVFSK 60
Query: 61 DASLMDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIIT 120
DASLMDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIIT
Sbjct: 61 DASLMDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIIT 120
Query: 121 KTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIET 180
KTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIET
Sbjct: 121 KTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIET 180
Query: 181 RRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSM 240
RRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSM
Sbjct: 181 RRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSM 240
Query: 241 RGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEE 300
RGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEE
Sbjct: 241 RGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEE 300
Query: 301 DLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELD 360
DLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELD
Sbjct: 301 DLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELD 360
Query: 361 SKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEEN 420
SKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEEN
Sbjct: 361 SKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEEN 420
Query: 421 IHYYEQCLATWESFLTSQTNLHLEEASEDKP 451
IHYYEQCLATWESFLTSQTNLHLEEASEDKP
Sbjct: 421 IHYYEQCLATWESFLTSQTNLHLEEASEDKP 451
>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
Length = 336
Score = 651 bits (1679), Expect = 0.0
Identities = 336/387 (86%), Positives = 336/387 (86%), Gaps = 51/387 (13%)
Query: 65 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR 124
MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR
Sbjct: 1 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR 60
Query: 125 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA 184
GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA
Sbjct: 61 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA 120
Query: 185 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK 244
LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK
Sbjct: 121 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK 180
Query: 245 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD 304
NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD
Sbjct: 181 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD 240
Query: 305 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE 364
TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE
Sbjct: 241 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE 300
Query: 365 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY 424
VLTYKKADTDL
Sbjct: 301 VLTYKKADTDL------------------------------------------------- 311
Query: 425 EQCLATWESFLTSQTNLHLEEASEDKP 451
CLATWESFLTSQTNLHLEEASEDKP
Sbjct: 312 --CLATWESFLTSQTNLHLEEASEDKP 336
>gi|153791707 sorting nexin family member 30 [Homo sapiens]
Length = 437
Score = 381 bits (978), Expect = e-106
Identities = 179/363 (49%), Positives = 264/363 (72%), Gaps = 5/363 (1%)
Query: 75 PTSPLSMINQIKFEDEPD--LKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEF 132
P S S++N+++ +D+ D +DLF+ VD+P+ HV T+ET+ITYRI TK++R EFD E+
Sbjct: 68 PASSSSLLNRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEY 127
Query: 133 EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRI 192
VRRRYQDF WL+ KLEE+ PT +IPPLPEKF+VKG+V+RF+++F+ETRRKAL KFL RI
Sbjct: 128 SVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRI 187
Query: 193 ADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFME 252
DHP L+FNE F IFLTA+ +L+++KKQG LL+RMG++V+ V + ++ RP EF
Sbjct: 188 TDHPVLSFNEHFNIFLTAK--DLNAYKKQGIALLTRMGESVKHVTGGYK-LRTRPLEFAA 244
Query: 253 MNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASC 312
+ ++++ F+ K+ ID+I+QRI KEE EY E++EYGP++ WSA E +L + L+ V++C
Sbjct: 245 IGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSAC 304
Query: 313 IDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKAD 372
I C A E+ ++E LPV+ EY+LYS+ + V+K+RDQ+QAE ++K+E + +K D
Sbjct: 305 IGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKED 364
Query: 373 TDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWE 432
+P ++ K +D++EC N LKAD ERW+ N + D + MA++NI YYE+CL WE
Sbjct: 365 RPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWE 424
Query: 433 SFL 435
S +
Sbjct: 425 SII 427
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 106 bits (264), Expect = 5e-23
Identities = 104/465 (22%), Positives = 190/465 (40%), Gaps = 68/465 (14%)
Query: 34 SSGSSALLQAEVLDLDEDEDDLEVFSKDASLMDMNSFSPMM---------PTSPLSMI-- 82
S+ S+ EV+ LD+D +DL + + +D P++ P +P ++I
Sbjct: 53 SANSNGPKPTEVV-LDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAP 111
Query: 83 -----------------NQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSRG 125
+I+ E D+ D+ I V +PE + ++ YR+ TKTS
Sbjct: 112 RIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLS 171
Query: 126 EFDSSEFEVRRRYQDFLWLKGKL--EEAHPTLIIPPLPEKFIV------KGMVERFNDDF 177
F SEF V+RR+ DFL L KL + H I+PP PEK IV G + + +F
Sbjct: 172 MFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEF 231
Query: 178 IETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAW--ELSSHKKQGPGLLSRMGQTVRA 235
+E RR AL ++L R HPTL + D + FL + +++ G G+L + + A
Sbjct: 232 VEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADA 291
Query: 236 VASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILW 295
V + F E E Q++ + + + +E + +
Sbjct: 292 VNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAML 351
Query: 296 SASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRD 353
SE+ L L +A ++ + +++ ++ +Y+ + GV R
Sbjct: 352 GNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRM 411
Query: 354 QI-QAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWE------------- 399
+ Q D+++ +L ++A+ ++ + DK++ A N ++ +WE
Sbjct: 412 KCWQKWEDAQITLLKKREAEAKMM---VANKPDKIQQAKNEIR-EWEAKVQQGERDFEQI 467
Query: 400 ---------RWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFL 435
R+++ D K E + +Q + WE+FL
Sbjct: 468 SKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFL 512
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 101 bits (251), Expect = 2e-21
Identities = 83/391 (21%), Positives = 174/391 (44%), Gaps = 31/391 (7%)
Query: 76 TSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVR 135
+ P +++ E++ D DL + + +PE + ++ Y++ T+TS F S +F V+
Sbjct: 125 SKPQPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVK 184
Query: 136 RRYQDFLWLKGKLEEAHPT--LIIPPLPEKFIV------KGMVERFNDDFIETRRKALHK 187
RR+ DFL L KL E H I+PP PEK ++ G + + +F+E RR AL +
Sbjct: 185 RRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALER 244
Query: 188 FLNRIADHPTLTFNEDFKIFLTAQAW--ELSSHKKQGPGLLSRMGQTVRAVASSMRGVKN 245
+L RI +HPT+ + D + FL + + + G GLL + AV+ +
Sbjct: 245 YLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNE 304
Query: 246 RPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEED--LV 303
F E +E Q++ + + + + +E ++ + +SE++ L
Sbjct: 305 SDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALS 364
Query: 304 DTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQI-QAELDSK 362
L +A ++ + +++ + L ++ +Y+ ++ +R + Q D++
Sbjct: 365 RALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQ 424
Query: 363 VEVLTYKKADTDLL----PEEIGKLEDKV--------------ECANNALKADWERWKQN 404
+ ++A+ LL P+++ + +D++ E + ++ + R+++
Sbjct: 425 ATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKE 484
Query: 405 MQNDIKLAFTDMAEENIHYYEQCLATWESFL 435
D K E ++ +Q WE+FL
Sbjct: 485 KSKDFKNHVIKYLETLLYSQQQLAKYWEAFL 515
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 99.8 bits (247), Expect = 5e-21
Identities = 102/457 (22%), Positives = 196/457 (42%), Gaps = 50/457 (10%)
Query: 18 GGANGESPGGGAPFPG----SSGSSALLQAEVLDLDEDEDDL----EVFSKDASLMDMNS 69
GG S PFPG S G++ + E D D + +D+ V SK S S
Sbjct: 5 GGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTS 64
Query: 70 FSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDS 129
++P + S N I E + + +DLF + ++ Y++ T+TS F S
Sbjct: 65 ---LLPINNGSKENGIHEEQDQEPQDLFAG--------DGMNAYVAYKVTTQTSLPLFRS 113
Query: 130 SEFEVRRRYQDFLWLKGKLEEAHPT--LIIPPLPEKFIV------KGMVERFNDDFIETR 181
+F V+RR+ DFL L KL E H I+PP PEK ++ G + + +F+E R
Sbjct: 114 KQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKR 173
Query: 182 RKALHKFLNRIADHPTLTFNEDFKIFLTAQAW--ELSSHKKQGPGLLSRMGQTVRAVASS 239
R AL ++L RI +HPT+ + D + FL + + + G GLL + AV+
Sbjct: 174 RAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKM 233
Query: 240 MRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASE 299
+ F E +E Q++ + + + + +E ++ + +SE
Sbjct: 234 TIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSE 293
Query: 300 ED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQI-Q 356
++ L L +A ++ + +++ + L ++ +Y+ ++ +R + Q
Sbjct: 294 DNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQ 353
Query: 357 AELDSKVEVLTYKKADTDLL----PEEIGKLEDKV--------------ECANNALKADW 398
D++ + ++A+ LL P+++ + +D++ E + ++ +
Sbjct: 354 RWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEV 413
Query: 399 ERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFL 435
R+++ D K E ++ +Q WE+FL
Sbjct: 414 IRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFL 450
>gi|4507145 sorting nexin 4 [Homo sapiens]
Length = 450
Score = 96.3 bits (238), Expect = 5e-20
Identities = 95/391 (24%), Positives = 168/391 (42%), Gaps = 57/391 (14%)
Query: 93 LKDLFITVDEPESH-----VTTIETFITYRIITKTSRGEFDSSEF--EVRRRYQDFLWLK 145
LK + I+V E E + ET+ Y I T++ S + RRY +F L+
Sbjct: 55 LKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLR 114
Query: 146 GKLEEAHPTLIIPPLPEK---FIV-KGMVERFNDDFIETRRKALHKFLNRIADHPTLTFN 201
L +P +++PPLPEK F+ K + + DF+E RR L FL RIA HP L +
Sbjct: 115 SYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRD 174
Query: 202 EDFKIFLTAQA-WELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELF 260
+ F +FLT + W+ + ++ G + ++A+ ++ R VKN + F ++ ++ +
Sbjct: 175 KIFYLFLTQEGNWKETVNE---TGFQLKADSRLKALNATFR-VKNPDKRFTDLKHYSDEL 230
Query: 261 SQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKAT 320
I+ + ++ R+ + YG + WSA E+++ D L+ +D +
Sbjct: 231 QSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSI 290
Query: 321 EKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLL---- 376
+ + E + EY+ Y+E L V ++ + +Q +L+ + L KK + L
Sbjct: 291 DDILED-EEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGT 349
Query: 377 ------------------PEE----IGKLEDKVECANNALK--------------ADWER 400
PE+ I LE+++ LK AD ER
Sbjct: 350 VRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIER 409
Query: 401 WKQNMQNDIKLAFTDMAEENIHYYEQCLATW 431
+K+ D+K A A I ++ + W
Sbjct: 410 FKEQKNRDLKEALISYAVMQISMCKKGIQVW 440
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 94.0 bits (232), Expect = 3e-19
Identities = 94/388 (24%), Positives = 164/388 (42%), Gaps = 73/388 (18%)
Query: 76 TSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVR 135
+ P +++ E++ D DL + + +PE + ++ Y++ T+TS F S +F V+
Sbjct: 125 SKPQPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVK 184
Query: 136 RRYQDFLWLKGKLEEAHPT--LIIPPLPEKFIV------KGMVERFNDDFIETRRKALHK 187
RR+ DFL L KL E H I+PP PEK ++ G + + +F+E RR AL +
Sbjct: 185 RRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALER 244
Query: 188 FLNRIADHPTLTFNEDFKIFLTAQAW--ELSSHKKQGPGLLSRMGQTVRAVASSMRGVKN 245
+L RI +HPT+ + D + FL + + + G GLL + AV+
Sbjct: 245 YLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMT----- 299
Query: 246 RPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDT 305
++MN F +K+ ++ QR+ K +H A E LV+
Sbjct: 300 -----IKMNESDIWFEEKLQEVECEEQRLRK--------------LH----AVVETLVNH 336
Query: 306 LKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEV 365
K++A + K S A+L + S L + AE++ K+E
Sbjct: 337 RKELALNTAQFAK---------SLAMLGSSEDNTALSRALSQL--------AEVEEKIEQ 379
Query: 366 LTYKKADTD--LLPE----------------EIGKLEDKVECANNALKADWERWKQNMQN 407
L ++A+ D LL E + + E E + ++ + R+++
Sbjct: 380 LHQEQANNDFFLLAELLSDYIRLLAIVRWESRVTQYERDFERISTVVRKEVIRFEKEKSK 439
Query: 408 DIKLAFTDMAEENIHYYEQCLATWESFL 435
D K E ++ +Q WE+FL
Sbjct: 440 DFKNHVIKYLETLLYSQQQLAKYWEAFL 467
>gi|4507143 sorting nexin 3 isoform a [Homo sapiens]
Length = 162
Score = 73.6 bits (179), Expect = 4e-13
Identities = 44/123 (35%), Positives = 64/123 (52%), Gaps = 6/123 (4%)
Query: 91 PDLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEE 150
P L I V P++ F TY I KT+ F E VRRRY DF WL+ +LE
Sbjct: 24 PPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELER 83
Query: 151 AHPTLIIPPLPEKFIVKGMVER-----FNDDFIETRRKALHKFLNRIADHPTLTFNEDFK 205
+++PPLP K ++ + R F+D+FIE R++ L +F+N++A HP
Sbjct: 84 -ESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLH 142
Query: 206 IFL 208
+FL
Sbjct: 143 MFL 145
>gi|23111030 sorting nexin 12 [Homo sapiens]
Length = 162
Score = 70.9 bits (172), Expect = 2e-12
Identities = 44/127 (34%), Positives = 64/127 (50%), Gaps = 6/127 (4%)
Query: 91 PDLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEE 150
P L I + P++ F TY + +T+ F E VRRRY DF WLK +LE
Sbjct: 25 PPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELER 84
Query: 151 AHPTLIIPPLPEKFIVKGMVER-----FNDDFIETRRKALHKFLNRIADHPTLTFNEDFK 205
+++PPLP K + + + R F + FIE RR+ L +F+N+IA HP
Sbjct: 85 -DSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLH 143
Query: 206 IFLTAQA 212
+FL +A
Sbjct: 144 MFLQEEA 150
>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
Length = 591
Score = 67.4 bits (163), Expect = 3e-11
Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 19/131 (14%)
Query: 99 TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 156
T+D+P ++ ++++I+Y+++ ++ V RRY+ F WL +L E P +
Sbjct: 279 TIDDPTKQTKFKGMKSYISYKLVPT-------HTQVPVHRRYKHFDWLYARLAEKFPVIS 331
Query: 157 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA------ 210
+P LPEK RF +DFI RRK L ++N +A HP L + F+ FLT
Sbjct: 332 VPHLPEK----QATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDE 387
Query: 211 QAWELSSHKKQ 221
+AW+ K +
Sbjct: 388 KAWKQGKRKAE 398
>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
Length = 624
Score = 67.4 bits (163), Expect = 3e-11
Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 19/131 (14%)
Query: 99 TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 156
T+D+P ++ ++++I+Y+++ ++ V RRY+ F WL +L E P +
Sbjct: 279 TIDDPTKQTKFKGMKSYISYKLVPT-------HTQVPVHRRYKHFDWLYARLAEKFPVIS 331
Query: 157 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA------ 210
+P LPEK RF +DFI RRK L ++N +A HP L + F+ FLT
Sbjct: 332 VPHLPEK----QATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDE 387
Query: 211 QAWELSSHKKQ 221
+AW+ K +
Sbjct: 388 KAWKQGKRKAE 398
>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
Length = 628
Score = 67.4 bits (163), Expect = 3e-11
Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 19/131 (14%)
Query: 99 TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 156
T+D+P ++ ++++I+Y+++ ++ V RRY+ F WL +L E P +
Sbjct: 279 TIDDPTKQTKFKGMKSYISYKLVPT-------HTQVPVHRRYKHFDWLYARLAEKFPVIS 331
Query: 157 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA------ 210
+P LPEK RF +DFI RRK L ++N +A HP L + F+ FLT
Sbjct: 332 VPHLPEK----QATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDE 387
Query: 211 QAWELSSHKKQ 221
+AW+ K +
Sbjct: 388 KAWKQGKRKAE 398
>gi|23111047 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 58.2 bits (139), Expect = 2e-08
Identities = 74/343 (21%), Positives = 137/343 (39%), Gaps = 34/343 (9%)
Query: 114 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVKGMVE 171
+ + + TKT+ F S EF V R+++DF+WL L E + LIIPP P K G E
Sbjct: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104
Query: 172 RF-----------NDDF------IETRRKALHK--------FLNRIADHPTLTFNEDFKI 206
+ ++F +E A+ K FL R++ HP L+ + +F +
Sbjct: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164
Query: 207 FLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSM--RGVKNRPEEFMEMNNFIELFSQKI 264
FL +LS +K + ++V A + GVK + F + NF+ + +I
Sbjct: 165 FLEYDQ-DLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRI 223
Query: 265 NLIDKISQRIYKEEREYFDE-MKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKR 323
+ ++ + + D+ + +H L + L VA ++ K +
Sbjct: 224 KDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRV 283
Query: 324 MSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL---TYKKADTDLLPEEI 380
S L ++ Y+L E ++ RR + + ++ + L K D L
Sbjct: 284 SSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQ 343
Query: 381 GKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHY 423
+ K E + + K + +K+ + +M+E I +
Sbjct: 344 QECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKH 386
>gi|7657599 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 58.2 bits (139), Expect = 2e-08
Identities = 74/343 (21%), Positives = 137/343 (39%), Gaps = 34/343 (9%)
Query: 114 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVKGMVE 171
+ + + TKT+ F S EF V R+++DF+WL L E + LIIPP P K G E
Sbjct: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104
Query: 172 RF-----------NDDF------IETRRKALHK--------FLNRIADHPTLTFNEDFKI 206
+ ++F +E A+ K FL R++ HP L+ + +F +
Sbjct: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164
Query: 207 FLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSM--RGVKNRPEEFMEMNNFIELFSQKI 264
FL +LS +K + ++V A + GVK + F + NF+ + +I
Sbjct: 165 FLEYDQ-DLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRI 223
Query: 265 NLIDKISQRIYKEEREYFDE-MKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKR 323
+ ++ + + D+ + +H L + L VA ++ K +
Sbjct: 224 KDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRV 283
Query: 324 MSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL---TYKKADTDLLPEEI 380
S L ++ Y+L E ++ RR + + ++ + L K D L
Sbjct: 284 SSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQ 343
Query: 381 GKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHY 423
+ K E + + K + +K+ + +M+E I +
Sbjct: 344 QECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKH 386
>gi|23111026 sorting nexin 11 [Homo sapiens]
Length = 270
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 4/100 (4%)
Query: 112 TFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVE 171
+++ Y+I T+ F + VRRRY++F+WL+ +L+ + +P LP K G
Sbjct: 34 SYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPVPELPGKSTFFGT-- 91
Query: 172 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQ 211
+D+FIE RR+ L FL ++ L + +FL +Q
Sbjct: 92 --SDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQSQ 129
>gi|23111028 sorting nexin 11 [Homo sapiens]
Length = 270
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 4/100 (4%)
Query: 112 TFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVE 171
+++ Y+I T+ F + VRRRY++F+WL+ +L+ + +P LP K G
Sbjct: 34 SYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPVPELPGKSTFFGT-- 91
Query: 172 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQ 211
+D+FIE RR+ L FL ++ L + +FL +Q
Sbjct: 92 --SDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQSQ 129
>gi|23397574 sorting nexin 33 [Homo sapiens]
Length = 574
Score = 53.9 bits (128), Expect = 3e-07
Identities = 36/128 (28%), Positives = 66/128 (51%), Gaps = 16/128 (12%)
Query: 99 TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 156
+V++P ++ I+++I+Y++ T T V RRY+ F WL +L +
Sbjct: 233 SVEDPTKQTKFKGIKSYISYKL-TPTHAAS------PVYRRYKHFDWLYNRLLHKFTVIS 285
Query: 157 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA---QAW 213
+P LPEK RF +DFIE R++ L +++ + HP L+ E F+ FL+ + W
Sbjct: 286 VPHLPEK----QATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQW 341
Query: 214 ELSSHKKQ 221
++ + +
Sbjct: 342 KMGKRRAE 349
>gi|88703041 sorting nexin 6 isoform b [Homo sapiens]
Length = 418
Score = 52.8 bits (125), Expect = 6e-07
Identities = 76/356 (21%), Positives = 145/356 (40%), Gaps = 41/356 (11%)
Query: 114 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKL--EEAHPTLIIPPLP---------E 162
+ + + TK+S F +EF V R++++F+WL E + IIPP P E
Sbjct: 58 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE 117
Query: 163 KF--IVKGMVERFNDDFIETRRK-------------ALHK-FLNRIADHPTLTFNEDFKI 206
K + +G ++F + +++ A+H+ FL R+A HP L + +F +
Sbjct: 118 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV 177
Query: 207 FLTAQAWELSSHKKQGPGLLSRMGQTVRAVASS--MRGVKNRPEEFMEMNNFIELFSQKI 264
FL +LS K L + + A + GVK+ + F F+ + ++
Sbjct: 178 FLEYNQ-DLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRV 236
Query: 265 NLIDKISQRIYKEEREYFDEMKEYG-PIHILWSASEEDLVDTLKDVASCIDRCCKATEKR 323
S R+ + + D+ G ++ L + D+ V+ D+ K +
Sbjct: 237 KDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARV 296
Query: 324 MSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKA-DTDLLPEEIG- 381
+ L ++ Y+ S+ ++ RR + + ++ + L +A + D+L E
Sbjct: 297 SADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQ 356
Query: 382 -----KLEDKVECANNAL-KADWERWKQNMQNDIKLAFTDM--AEENIHYYEQCLA 429
K E E A L R +N ++LA ++ A+ N+ + CLA
Sbjct: 357 QLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLA 412
>gi|23943858 sorting nexin 8 [Homo sapiens]
Length = 465
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 7/98 (7%)
Query: 126 EFDSSEFE--VRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRK 183
E S F+ V RRY DF+ + L P ++P LP K ++ + +FIE RR+
Sbjct: 96 EVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGA-----DREFIEARRR 150
Query: 184 ALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQ 221
AL +F+N +A HP + + K+FL+ ++ + K+
Sbjct: 151 ALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKE 188
>gi|72534838 sorting nexin 6B [Homo sapiens]
Length = 403
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/289 (21%), Positives = 121/289 (41%), Gaps = 40/289 (13%)
Query: 114 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKL--EEAHPTLIIPPLPEKFIVKGMVE 171
+ + + TK+ F +EF V R++++F+WL E + LIIPP P + + E
Sbjct: 40 VKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASRE 99
Query: 172 RF-----------NDDFIETRRK-------------ALHK-FLNRIADHPTLTFNEDFKI 206
+ ++F + +++ A+H+ FL R+A HPTL + +F +
Sbjct: 100 KLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFV 159
Query: 207 FLTAQAWELSSHKKQGPGLLSRMGQTV-----RAVASSMRGVKNRPEEFMEMNNFIELFS 261
FL +LS K LL + + A+ + M G+K + F F+ +
Sbjct: 160 FL-EYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYH 218
Query: 262 QKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLK----DVASCIDRCC 317
+I + R+ + + D +Y PI S+ V+ L+ +A +R
Sbjct: 219 TRIRDACLRADRVMRAHKCLAD---DYIPISAALSSLGTQEVNQLRTSFLKLAELFERLR 275
Query: 318 KATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL 366
K + S L ++ Y+ S+ ++ RR + A+ ++ + L
Sbjct: 276 KLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKAL 324
>gi|7706706 sorting nexin 9 [Homo sapiens]
Length = 595
Score = 48.9 bits (115), Expect = 9e-06
Identities = 66/333 (19%), Positives = 131/333 (39%), Gaps = 36/333 (10%)
Query: 110 IETFITYRII-TKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI-IPPLPEKFIVK 167
++++I Y++ T T+R V RY+ F WL +L + I IP LP+K +
Sbjct: 266 LKSYIEYQLTPTNTNRS--------VNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTG 317
Query: 168 GMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLT---AQAWELSSHKKQGPG 224
RF ++FI+ R + L ++ R+ HP ++ +E F+ FL + W+ K +
Sbjct: 318 ----RFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDE 373
Query: 225 LLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKE-----ER 279
L M + + + ++ + F + + + + Q +K +
Sbjct: 374 LAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPK 433
Query: 280 EYFDEMKEYGPIHILWSAS----EEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVV 335
EY K + ++S+S E DL D + + + ++ L+
Sbjct: 434 EYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN 493
Query: 336 HEYVLYSEM---LMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANN 392
HEY + ++G K + E D V A + + ++ + +V +
Sbjct: 494 HEYKGFLGCFPDIIGTHKGAIEKVKESDKLV-------ATSKITLQDKQNMVKRVSIMSY 546
Query: 393 ALKADWERWKQNMQNDIKLAFTDMAEENIHYYE 425
AL+A+ + N D E+ + +YE
Sbjct: 547 ALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYE 579
>gi|23111023 sorting nexin 10 [Homo sapiens]
Length = 201
Score = 48.5 bits (114), Expect = 1e-05
Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 112 TFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVE 171
++I Y I T+ F VRRRY++F+WL+ +L+ + +P LP K + M
Sbjct: 28 SYIDYEICIHTNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNN 87
Query: 172 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFL 208
R ++ RR+ L FL ++ + L + +FL
Sbjct: 88 R---QHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFL 121
>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
Length = 893
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
Query: 128 DSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHK 187
+ + V RRY +F L+ KL E H LP K I+ N +F++++R+ +
Sbjct: 554 EPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPK----NYEFLKSKREEFQE 609
Query: 188 FLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRP 247
+L ++ HP L+ ++ FL+ E K P + +G+ +++V + K +
Sbjct: 610 YLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDV--NLGKIIKSVPGKLMKEKGQH 667
Query: 248 EEFMEMN 254
E MN
Sbjct: 668 LEPFIMN 674
>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
Length = 946
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
Query: 128 DSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHK 187
+ + V RRY +F L+ KL E H LP K I+ N +F++++R+ +
Sbjct: 607 EPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPK----NYEFLKSKREEFQE 662
Query: 188 FLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRP 247
+L ++ HP L+ ++ FL+ E K P + +G+ +++V + K +
Sbjct: 663 YLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDV--NLGKIIKSVPGKLMKEKGQH 720
Query: 248 EEFMEMN 254
E MN
Sbjct: 721 LEPFIMN 727
>gi|23111041 sorting nexin 3 isoform b [Homo sapiens]
Length = 130
Score = 43.1 bits (100), Expect = 5e-04
Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 150 EAHPTLIIPPLPEKFIVKGMVER-----FNDDFIETRRKALHKFLNRIADHPTLTFNEDF 204
E +++PPLP K ++ + R F+D+FIE R++ L +F+N++A HP
Sbjct: 50 EIRVKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCL 109
Query: 205 KIFL 208
+FL
Sbjct: 110 HMFL 113
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 42.7 bits (99), Expect = 7e-04
Identities = 45/235 (19%), Positives = 94/235 (40%), Gaps = 11/235 (4%)
Query: 224 GLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKE------ 277
GLL +G+T +A++ K+ +EF F QK ++ + ++R+ +E
Sbjct: 793 GLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSK 852
Query: 278 EREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHE 337
E + FD G + S ++L + ++V ++ + ++++ L V E
Sbjct: 853 EAQKFD--SSLGALKTELSYKTQELQEKTREVQERLNE-MEQLKEQLENRDSTLQTVERE 909
Query: 338 YVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKAD 397
L +E L ++ + E D ++ + + D L +I + L+
Sbjct: 910 KTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNA 969
Query: 398 WERWKQNMQ--NDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDK 450
E KQ+ + N +K ++ N+H E T + F + ++ E K
Sbjct: 970 LESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAK 1024
Score = 29.6 bits (65), Expect = 5.8
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 22/193 (11%)
Query: 243 VKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDL 302
+K + +M N I+L+ ++ K+ + KE + F+E+ + ++ +DL
Sbjct: 655 MKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKL--TSLIDGKVPKDL 712
Query: 303 VDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEML---MGVMKRRDQIQ--- 356
+ L+ D +K ++ E + E +L SE+ V + R +IQ
Sbjct: 713 LCNLELEGKITD-----LQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKS 767
Query: 357 -------AELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWK--QNMQN 407
+E D + +K++ L EEIGK +D + + K+ + ++ + +
Sbjct: 768 EELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHM 827
Query: 408 DIKLAFTDMAEEN 420
D + + + EEN
Sbjct: 828 DFEQKYKMVLEEN 840
>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 42.7 bits (99), Expect = 7e-04
Identities = 59/229 (25%), Positives = 94/229 (41%), Gaps = 33/229 (14%)
Query: 113 FITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHP--TLIIPPLPEKFIVKGMV 170
F Y+I+ K + E + V RRY DF L KL+E P L +PP +
Sbjct: 124 FTVYKILVKKTPEE----SWVVFRRYTDFSRLNDKLKEMFPGFRLALPP------KRWFK 173
Query: 171 ERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMG 230
+ +N DF+E R+ L FL + H + + FL PG +
Sbjct: 174 DNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD---------DPPGPFDSLE 224
Query: 231 QTVRAVASSM-----RGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYK---EEREYF 282
++ RA ++ R K E+ EM + +L S+K ID + RI E E
Sbjct: 225 ES-RAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESL 283
Query: 283 DEMKEYGP--IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSE 329
D + G + + SA E D D L + + ++ C + + + +SE
Sbjct: 284 DVSETEGEQILKVESSALEVD-QDVLDEESRADNKPCLSFSEPENAVSE 331
>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 42.7 bits (99), Expect = 7e-04
Identities = 59/229 (25%), Positives = 94/229 (41%), Gaps = 33/229 (14%)
Query: 113 FITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHP--TLIIPPLPEKFIVKGMV 170
F Y+I+ K + E + V RRY DF L KL+E P L +PP +
Sbjct: 124 FTVYKILVKKTPEE----SWVVFRRYTDFSRLNDKLKEMFPGFRLALPP------KRWFK 173
Query: 171 ERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMG 230
+ +N DF+E R+ L FL + H + + FL PG +
Sbjct: 174 DNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD---------DPPGPFDSLE 224
Query: 231 QTVRAVASSM-----RGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYK---EEREYF 282
++ RA ++ R K E+ EM + +L S+K ID + RI E E
Sbjct: 225 ES-RAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESL 283
Query: 283 DEMKEYGP--IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSE 329
D + G + + SA E D D L + + ++ C + + + +SE
Sbjct: 284 DVSETEGEQILKVESSALEVD-QDVLDEESRADNKPCLSFSEPENAVSE 331
>gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1
isoform a [Homo sapiens]
Length = 1066
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 97 FITVDEPESHVTTIETF-ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTL 155
F TV EP+ H + +T R++++ R D E V +RY DF L +L + H L
Sbjct: 14 FYTVTEPQRHPRGYTVYKVTARVVSR--RNPEDVQEIIVWKRYSDFKKLHKELWQIHKNL 71
Query: 156 -----IIPPLPEKFIVKGMV-ERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIF 207
+ PP KG+V RF++ IE RR+ L A+ P L ++ + F
Sbjct: 72 FRHSELFPP-----FAKGIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDF 124
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,623,609
Number of Sequences: 37866
Number of extensions: 805515
Number of successful extensions: 4673
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 4519
Number of HSP's gapped (non-prelim): 180
length of query: 451
length of database: 18,247,518
effective HSP length: 106
effective length of query: 345
effective length of database: 14,233,722
effective search space: 4910634090
effective search space used: 4910634090
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.