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Search of human proteins with 194272183
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194272183 G protein-coupled receptor 124 [Homo sapiens]
(1338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194272183 G protein-coupled receptor 124 [Homo sapiens] 2733 0.0
gi|59823631 G protein-coupled receptor 125 [Homo sapiens] 963 0.0
gi|144922665 G protein-coupled receptor 123 [Homo sapiens] 341 2e-93
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 112 2e-24
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 112 2e-24
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 105 3e-22
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 103 8e-22
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 101 4e-21
gi|59710093 G-protein coupled receptor 112 [Homo sapiens] 99 2e-20
gi|109150416 peroxidasin [Homo sapiens] 96 3e-19
gi|194306623 immunoglobulin superfamily containing leucine-rich ... 96 3e-19
gi|194306621 immunoglobulin superfamily containing leucine-rich ... 96 3e-19
gi|39930401 immunoglobulin superfamily containing leucine-rich r... 96 3e-19
gi|194306618 immunoglobulin superfamily containing leucine-rich ... 96 3e-19
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 95 4e-19
gi|11321571 slit homolog 3 [Homo sapiens] 94 1e-18
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 92 3e-18
gi|61966761 leucine rich repeat containing 26 [Homo sapiens] 91 1e-17
gi|188528675 slit homolog 1 [Homo sapiens] 91 1e-17
gi|88702793 slit-like 2 [Homo sapiens] 88 5e-17
gi|21281681 leucine-rich repeat LGI family, member 3 [Homo sapiens] 87 8e-17
gi|4759146 slit homolog 2 [Homo sapiens] 86 2e-16
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 86 3e-16
gi|163792198 latrophilin 3 precursor [Homo sapiens] 86 3e-16
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 83 2e-15
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 83 2e-15
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] 83 2e-15
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] 83 2e-15
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens] 83 2e-15
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens] 83 2e-15
>gi|194272183 G protein-coupled receptor 124 [Homo sapiens]
Length = 1338
Score = 2733 bits (7084), Expect = 0.0
Identities = 1338/1338 (100%), Positives = 1338/1338 (100%)
Query: 1 MGAGGRRMRGAPARLLLPLLPWLLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPG 60
MGAGGRRMRGAPARLLLPLLPWLLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPG
Sbjct: 1 MGAGGRRMRGAPARLLLPLLPWLLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPG 60
Query: 61 PARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNII 120
PARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNII
Sbjct: 61 PARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNII 120
Query: 121 STVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELP 180
STVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELP
Sbjct: 121 STVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELP 180
Query: 181 ALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCE 240
ALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCE
Sbjct: 181 ALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCE 240
Query: 241 GALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAE 300
GALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAE
Sbjct: 241 GALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAE 300
Query: 301 SLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVAN 360
SLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVAN
Sbjct: 301 SLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVAN 360
Query: 361 NRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYT 420
NRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYT
Sbjct: 361 NRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYT 420
Query: 421 NDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQI 480
NDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQI
Sbjct: 421 NDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQI 480
Query: 481 KELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVNARN 540
KELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVNARN
Sbjct: 481 KELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVNARN 540
Query: 541 VALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSPGQNPPPEPEPPADQQLRFRCTTGR 600
VALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSPGQNPPPEPEPPADQQLRFRCTTGR
Sbjct: 541 VALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSPGQNPPPEPEPPADQQLRFRCTTGR 600
Query: 601 PNVSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNT 660
PNVSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNT
Sbjct: 601 PNVSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNT 660
Query: 661 SRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGE 720
SRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGE
Sbjct: 661 SRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGE 720
Query: 721 AGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPCTALL 780
AGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPCTALL
Sbjct: 721 AGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPCTALL 780
Query: 781 LLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGI 840
LLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGI
Sbjct: 781 LLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGI 840
Query: 841 TLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICG 900
TLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICG
Sbjct: 841 TLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICG 900
Query: 901 ITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKA 960
ITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKA
Sbjct: 901 ITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKA 960
Query: 961 GNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQLG 1020
GNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQLG
Sbjct: 961 GNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQLG 1020
Query: 1021 ALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASW 1080
ALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASW
Sbjct: 1021 ALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASW 1080
Query: 1081 RACCPPASPAAPHAPPRALPAAAEDGSPVFGEGPPSLKSSPSGSSGHPLALGPCKLTNLQ 1140
RACCPPASPAAPHAPPRALPAAAEDGSPVFGEGPPSLKSSPSGSSGHPLALGPCKLTNLQ
Sbjct: 1081 RACCPPASPAAPHAPPRALPAAAEDGSPVFGEGPPSLKSSPSGSSGHPLALGPCKLTNLQ 1140
Query: 1141 LAQSQVCEAGAAAGGEGEPEPAGTRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKNR 1200
LAQSQVCEAGAAAGGEGEPEPAGTRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKNR
Sbjct: 1141 LAQSQVCEAGAAAGGEGEPEPAGTRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKNR 1200
Query: 1201 LKALRGGAAGALELLSSESGSLHNSPTDSYLGSSRNSPGAGLQLEGEPMLTPSEGSDTSA 1260
LKALRGGAAGALELLSSESGSLHNSPTDSYLGSSRNSPGAGLQLEGEPMLTPSEGSDTSA
Sbjct: 1201 LKALRGGAAGALELLSSESGSLHNSPTDSYLGSSRNSPGAGLQLEGEPMLTPSEGSDTSA 1260
Query: 1261 APLSEAGRAGQRRSASRDSLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAE 1320
APLSEAGRAGQRRSASRDSLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAE
Sbjct: 1261 APLSEAGRAGQRRSASRDSLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAE 1320
Query: 1321 VASGGCMKTGLWKSETTV 1338
VASGGCMKTGLWKSETTV
Sbjct: 1321 VASGGCMKTGLWKSETTV 1338
>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
Length = 1321
Score = 963 bits (2490), Expect = 0.0
Identities = 588/1372 (42%), Positives = 790/1372 (57%), Gaps = 93/1372 (6%)
Query: 5 GRRMRGAPARLLLPLLPWLLLLLAPEARGAPGCPLSIRS-CKCSGERPKGLSGGVPGPAR 63
GRR A LLLPL LL LLA G G ++ + CK G RP+G +G G A
Sbjct: 5 GRRRGRAQPPLLLPLS--LLALLALLGGGGGGGAAALPAGCKHDG-RPRG-AGRAAGAAE 60
Query: 64 RRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTV 123
+VVCS +L + P LPN TVTL+LSNNKI+ L+NGSF GLSLLE+LDLRNN+IS++
Sbjct: 61 GKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSI 120
Query: 124 QPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALK 183
PGAF GL LKRLDL+NNRIGCL ++ F+GL L+RLN+SGN+FSSL G FD L +L+
Sbjct: 121 DPGAFWGLSSLKRLDLTNNRIGCLNADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLR 180
Query: 184 VVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGAL 243
++ TE+L CDC++ W+ W + +++ + + T C YP +L AQ + +++ L C+ L
Sbjct: 181 SLEFQTEYLLCDCNILWMHRWVKEKNITVRD-TRCVYPKSLQAQPVTGVKQELLTCDPPL 239
Query: 244 ELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLI 303
EL + ++ PS RQVVF+GD LPFQC ASY+ D ++ WY + VE DE GI + +++I
Sbjct: 240 ELPSFYMTPSHRQVVFEGDSLPFQCMASYIDQDMQVLWYQDGRIVETDESQGIFVEKNMI 299
Query: 304 HDCTFITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVANNRG 363
H+C+ I S LT+S+I ++G W C V +GN ++ V+IVVLE+SA YCP ERV NN+G
Sbjct: 300 HNCSLIASALTISNIQAGSTGNWGCHVQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKG 359
Query: 364 DFRWPRTLAGITAYQSCLQYPFTS-VPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYTND 422
DFRWPRTLAGITAY C + S + G +A RRCDR G W DYS C Y ND
Sbjct: 360 DFRWPRTLAGITAYLQCTRNTHGSGIYPGNPQDERKAWRRCDRGGFWADDDYSRCQYAND 419
Query: 423 ITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYV--DQI 480
+TRVLY F MP+N +NA+ A QL YT EAA+FSD MDV++VA+MI+KF + ++
Sbjct: 420 VTRVLYMFNQMPLNLTNAVATARQLLAYTVEAANFSDKMDVIFVAEMIEKFGRFTKEEKS 479
Query: 481 KELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVNARN 540
KEL +VMVD+ASN+ML DE +LWLAQRE KACSRIV L+RI L+ A S + N
Sbjct: 480 KELGDVMVDIASNIMLADERVLWLAQREAKACSRIVQCLQRIATYRLAGGAHVYSTYSPN 539
Query: 541 VALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSPGQNPPPEPEPPADQQLRFRCTTGR 600
+ALEAY+IK + G+TCT FQ+ V + +PE D+QL F+C
Sbjct: 540 IALEAYVIKSTGFTGMTCTVFQK----VAASDRTGLSDYGRRDPEGNLDKQLSFKCNVSN 595
Query: 601 PNVSLSSFHIKNSVALASIQLPPSLFS-SLPAALAPPVPPDCTLQLLVFRNGRLFHSHSN 659
+ SS +KN++ ASIQLPPSLFS L P LQL+ FRNG+LF + N
Sbjct: 596 ---TFSSLALKNTIVEASIQLPPSLFSPKQKRELRPTDDSLYKLQLIAFRNGKLFPATGN 652
Query: 660 TSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPG 719
++ A GKRR V TPVI G V PV V+LR A GA+ VAA W +
Sbjct: 653 ST--NLADDGKRRTVVTPVILTKIDGVNVDTHHIPVNVTLRRIAHGADAVAARWDFDLLN 710
Query: 720 EAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPCTAL 779
GGW S+GC + S N++ + C L N AVLM+L+ A LHPVVY +
Sbjct: 711 GQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQAASL-LHPVVYTTAII 769
Query: 780 LLLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVG 839
LLLCL A I++YI +HS IR+S K WHML+NLCFHI +T VF GGIT T +CQAVG
Sbjct: 770 LLLCLLAVIVSYIYHHSLIRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASICQAVG 829
Query: 840 ITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIIC 899
I LHYS+L+T+LW+GV AR ++K++T +A Q+ D P P PMLRFYLI GGIP+I+C
Sbjct: 830 IILHYSTLATVLWVGVTARNIYKQVTKKAKRCQDPDEPPPPPRPMLRFYLIGGGIPIIVC 889
Query: 900 GITAAVNIHNY--RDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRL-----RG 952
GITAA NI NY R ++PYCW+ W PSLGAFY P + I + +YFL ++L R
Sbjct: 890 GITAAANIKNYGSRPNAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERK 949
Query: 953 PLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSL 1012
+ P R + E+ S S SL++T + E+ +
Sbjct: 950 YELKEPTEEQQRLAANENGEINHQD---------SMSLSLISTSAL--------ENEHTF 992
Query: 1013 YSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCAR 1072
+S QL T LY+A+W GALAVS + +V S ++G + + F HHC
Sbjct: 993 HS---QLLGASLTLLLYVALWMFGALAVSLYYPLDLVFSFVFGATSLSFSAFFVVHHCVN 1049
Query: 1073 RRDVRASW-RACCPPASPAAPHA---PPRALPAAAEDGSPVFGEGPPSLKSSPSGSSGHP 1128
R DVR +W CCP S + PP + + GE P SS S +
Sbjct: 1050 REDVRLAWIMTCCPGRSSYSVQVNVQPP--------NSNGTNGEAPKCPNSSAESSCTNK 1101
Query: 1129 LALG------PCKLTNLQLAQSQVCEAGAAAGGEGEPEPAGTRGNL-----AHRHPNNVH 1177
A CKLTNLQ A +Q + + + T ++ H P V
Sbjct: 1102 SASSFKNSSQGCKLTNLQAAAAQCHANSLPLNSTPQLDNSLTEHSMDNDIKMHVAPLEVQ 1161
Query: 1178 -----HGRRAHKSRAKGHRAGEACGKNRLKALRGGAAGALELLSSESGSLHNSPTDSYLG 1232
H R HK+R+KGHRA +RL LR A ++ +S GS+ N S LG
Sbjct: 1162 FRTNVHSSRHHKNRSKGHRA------SRLTVLR---EYAYDVPTSVEGSVQNGLPKSRLG 1212
Query: 1233 SSR---NSPGAGLQLEGEPMLTPSEGSDTSAAPLSEAGRAGQR---RSASRDSLKGGGAL 1286
++ S A L P + S + + L ++ R ++ ++ +D+L+ +
Sbjct: 1213 NNEGHSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRNFEKPVSTTSKKDALRKPAVV 1272
Query: 1287 EKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 1338
E E+ ++SY LN A NG K + L+G + S G ++TGLWK ETTV
Sbjct: 1273 ELENQQKSYGLNLAIQNGPIKSNGQEG-PLLGTD--STGNVRTGLWKHETTV 1321
>gi|144922665 G protein-coupled receptor 123 [Homo sapiens]
Length = 560
Score = 341 bits (875), Expect = 2e-93
Identities = 235/589 (39%), Positives = 297/589 (50%), Gaps = 58/589 (9%)
Query: 766 GAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGG 825
G LHPVVY CTA++LLCL A+ +TYI++ S+IR+SRKG H LLN CFH A+T VFAGG
Sbjct: 14 GEFLHPVVYACTAVMLLCLLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGG 73
Query: 826 ITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPML 885
I T Y ++CQAVGI LHYS+LST+LW+GV AR ++K++T +AP + D P+L
Sbjct: 74 INRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPYPRQPLL 133
Query: 886 RFYLIAGGIPLIICGITAAVNIHNY---RDHSPYCWLVWRPSLGAFYIPVALILLITWIY 942
RFYL++GG+P IICG+TAA NI NY + + YCW+ W PSLGAFY P A+I L+T +Y
Sbjct: 134 RFYLVSGGVPFIICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVY 193
Query: 943 FLCAGLRLRG------PLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATG 996
FL ++LR L P+ A+ E G +R T P S+L
Sbjct: 194 FLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGRGIRPGTPPAHDAP----GASVL--- 246
Query: 997 SARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGV 1056
+ +S QL A T FL+ A WA GALAVSQ +V SCLYG
Sbjct: 247 -------------QNEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGA 293
Query: 1057 AASALGLFVFTHHCARRRDVRASWRACCPPASPAAP--HAPPRALPAAAEDGSPVFGEGP 1114
LGLFV HHCA+R DV W ACCPP A P A AL AA SP G+
Sbjct: 294 FCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPALDANGAALGRAACLHSPGLGQ-- 351
Query: 1115 PSLKSSPSGSSGHPLALGPCKLTNLQLAQSQVCEAGAAAGGEGEPEPAGTRGNLAHRHPN 1174
P G + P GPCK+TNLQ AQ A + + AH H
Sbjct: 352 ------PRGFAHPP---GPCKMTNLQAAQGHASCLSPATPCCAKMHCEPLTADEAHVHLQ 402
Query: 1175 NVHHGRRAHKSRAKGHRAGEACGKNRLKALRGGAAGALELLSSESGSLHNSPTDSYLGSS 1234
G H G G + A + SS GS +S TDS S
Sbjct: 403 --EEGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRSSRTDSPPSSL 460
Query: 1235 RNSPGAG-----LQLEGEPMLTPSEGSDTSAAPLSEAGRAGQRRSASRDSLKGGGALEKE 1289
G Q + PM+T EGSD S A S + G R++ G G LE
Sbjct: 461 DGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPG------REAALGPGHLEML 514
Query: 1290 SHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 1338
+S P S NG PKG + + G + G ++TG WK+ETTV
Sbjct: 515 RRTQSLPFGGPSQNGLPKGKLLEGLP-FGTD--GTGNIRTGPWKNETTV 560
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 112 bits (280), Expect = 2e-24
Identities = 78/263 (29%), Positives = 128/263 (48%), Gaps = 7/263 (2%)
Query: 88 TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIIS-TVQP--GAFLGLGELKRLDLSNNRI 144
TL + NN+++ + + +F GLS L+ LDL+NN IS T++ GAF GL +L+RL L NRI
Sbjct: 339 TLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRI 398
Query: 145 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 204
+T + F GL L L++S N SLQ F ++ L+ + L T L CDC L+WL W
Sbjct: 399 RSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQW 458
Query: 205 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRL 264
+ Q + CA+P L +++ ++ C+ + + Q +G L
Sbjct: 459 VAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPK--PQITVQPETQSAIKGSNL 516
Query: 265 PFQCS-ASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWAS 323
F CS AS + W + + E + + T+ L L + +
Sbjct: 517 SFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASE 576
Query: 324 GEWECTVSMAQGNA-SKKVEIVV 345
G+++C +S G++ S K ++ V
Sbjct: 577 GKYQCVISNHFGSSYSVKAKLTV 599
Score = 52.4 bits (124), Expect = 3e-06
Identities = 34/112 (30%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Query: 76 PPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELK 135
PP+ LP L L+ NKI + +F GL L+ L ++ N ++ + GAF GL ++
Sbjct: 208 PPKMFKLPQ-LQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNME 266
Query: 136 RLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 187
L L +N + +T GL L L++S N + + P ++ L +DL
Sbjct: 267 ILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDL 318
Score = 52.4 bits (124), Expect = 3e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Query: 88 TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 147
+L + N +T L +G+F GLS +E L L +N ++ + G GL L+ L LS N I +
Sbjct: 243 SLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRI 302
Query: 148 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLT--CDCHLRWL 201
+ + ++ +L L+++ N S L F L L + +G ++ DC R L
Sbjct: 303 SPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGL 358
Score = 51.6 bits (122), Expect = 5e-06
Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 3/130 (2%)
Query: 89 LLLSNNKITGLRNGSFLGLS-LLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 147
L L++N++T + G F L+ L L L N IS + P F L +L+ L+L+ N+I +
Sbjct: 172 LYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNV 230
Query: 148 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQN 207
TFQGL L L + N + L G F L ++++ L LT + WL
Sbjct: 231 DGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLT-EITKGWLYGLLML 289
Query: 208 RSLQLSEHTL 217
+ L LS++ +
Sbjct: 290 QELHLSQNAI 299
Score = 47.4 bits (111), Expect = 9e-05
Identities = 59/225 (26%), Positives = 97/225 (43%), Gaps = 36/225 (16%)
Query: 50 RPKGLSGGVPGPARRRVV-----CSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSF 104
+P G++ P P R + CS L PEP LP+ L LS+N+++ ++ S
Sbjct: 37 QPSGVAAERPCPTTCRCLGDLLDCSRKRLARLPEP--LPSWVARLDLSHNRLSFIKASSM 94
Query: 105 LGLSLLEKLDLRNNIISTVQ-----------------------PGAFLGLGELKRLDLSN 141
L L ++ L NN + T+ P L+ LDLS+
Sbjct: 95 SHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSS 154
Query: 142 NRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELP-ALKVVDLGTEFLTCDCHLRW 200
N I L + F L +L L ++ N +S++PG FD L L V+ L ++ +
Sbjct: 155 NNISELQT-AFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMF 212
Query: 201 LLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALEL 245
LP Q+ L+L+ + + L Q LG+L+ ++ G +L
Sbjct: 213 KLPQLQH--LELNRNKI-KNVDGLTFQGLGALKSLKMQRNGVTKL 254
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 112 bits (280), Expect = 2e-24
Identities = 78/263 (29%), Positives = 128/263 (48%), Gaps = 7/263 (2%)
Query: 88 TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIIS-TVQP--GAFLGLGELKRLDLSNNRI 144
TL + NN+++ + + +F GLS L+ LDL+NN IS T++ GAF GL +L+RL L NRI
Sbjct: 279 TLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRI 338
Query: 145 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 204
+T + F GL L L++S N SLQ F ++ L+ + L T L CDC L+WL W
Sbjct: 339 RSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQW 398
Query: 205 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRL 264
+ Q + CA+P L +++ ++ C+ + + Q +G L
Sbjct: 399 VAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPK--PQITVQPETQSAIKGSNL 456
Query: 265 PFQCS-ASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWAS 323
F CS AS + W + + E + + T+ L L + +
Sbjct: 457 SFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASE 516
Query: 324 GEWECTVSMAQGNA-SKKVEIVV 345
G+++C +S G++ S K ++ V
Sbjct: 517 GKYQCVISNHFGSSYSVKAKLTV 539
Score = 52.4 bits (124), Expect = 3e-06
Identities = 34/112 (30%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Query: 76 PPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELK 135
PP+ LP L L+ NKI + +F GL L+ L ++ N ++ + GAF GL ++
Sbjct: 148 PPKMFKLPQ-LQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNME 206
Query: 136 RLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 187
L L +N + +T GL L L++S N + + P ++ L +DL
Sbjct: 207 ILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDL 258
Score = 52.4 bits (124), Expect = 3e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Query: 88 TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 147
+L + N +T L +G+F GLS +E L L +N ++ + G GL L+ L LS N I +
Sbjct: 183 SLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRI 242
Query: 148 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLT--CDCHLRWL 201
+ + ++ +L L+++ N S L F L L + +G ++ DC R L
Sbjct: 243 SPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGL 298
Score = 51.6 bits (122), Expect = 5e-06
Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 3/130 (2%)
Query: 89 LLLSNNKITGLRNGSFLGLS-LLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 147
L L++N++T + G F L+ L L L N IS + P F L +L+ L+L+ N+I +
Sbjct: 112 LYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNV 170
Query: 148 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQN 207
TFQGL L L + N + L G F L ++++ L LT + WL
Sbjct: 171 DGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLT-EITKGWLYGLLML 229
Query: 208 RSLQLSEHTL 217
+ L LS++ +
Sbjct: 230 QELHLSQNAI 239
Score = 43.1 bits (100), Expect = 0.002
Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 4/125 (3%)
Query: 64 RRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTV 123
R V + +L P G + L L+ N+I + LE LDL +N IS +
Sbjct: 41 REVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISEL 100
Query: 124 QPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPR-LLRLNISGNIFSSLQPGVFDELPAL 182
Q AF L +LK L L++NR+ + F L LL L ++ N S++ P +F +LP L
Sbjct: 101 QT-AFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMF-KLPQL 157
Query: 183 KVVDL 187
+ ++L
Sbjct: 158 QHLEL 162
Score = 36.2 bits (82), Expect = 0.22
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 29/179 (16%)
Query: 91 LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQ-----------------------PGA 127
LS+N+++ ++ S L L ++ L NN + T+ P
Sbjct: 21 LSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEH 80
Query: 128 FLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELP-ALKVVD 186
L+ LDLS+N I L + F L +L L ++ N +S++PG FD L L V+
Sbjct: 81 LKEFQSLETLDLSSNNISELQT-AFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLK 138
Query: 187 LGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALEL 245
L ++ + LP Q+ L+L+ + + L Q LG+L+ ++ G +L
Sbjct: 139 LNRNRISAIPPKMFKLPQLQH--LELNRNKI-KNVDGLTFQGLGALKSLKMQRNGVTKL 194
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 105 bits (262), Expect = 3e-22
Identities = 80/286 (27%), Positives = 130/286 (45%), Gaps = 8/286 (2%)
Query: 66 VVCSGGDLPEPPEPGLLPNGTVTLL-LSNNKITGLRNGSFLGLSLLEKLDLRNNIIS-TV 123
+V S +L E L ++++L LS+N I+ + G+F GL L LDL +N IS T+
Sbjct: 312 LVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTI 371
Query: 124 QP--GAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPA 181
+ GAF GL L +L L N+I + F GL L LN+ GN S+Q F ++
Sbjct: 372 EDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKN 431
Query: 182 LKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 241
LK + + ++ CDC L+WL PW R LQ CA+P +L Q++ S+ C+
Sbjct: 432 LKELHISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDD 491
Query: 242 ALELHTHHLIPSLRQVVFQGDRLPFQCS-ASYLGNDTRIRWYHNRAPVEGDEQAGILLAE 300
L+ + + G + F CS AS + W + + + +
Sbjct: 492 FLK--PQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVH 549
Query: 301 SLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGNA-SKKVEIVV 345
+ + T+ L L + G ++C ++ G+ S K + V
Sbjct: 550 AQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTV 595
Score = 67.4 bits (163), Expect = 9e-11
Identities = 65/210 (30%), Positives = 83/210 (39%), Gaps = 33/210 (15%)
Query: 10 GAPARLLLPLLPWLLLL--------LAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPG- 60
GAP R LL WLLLL P A A C + S C G L G +P
Sbjct: 10 GAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLDCGGRGLAALPGDLPSW 69
Query: 61 ----------------------PARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITG 98
P + V + +L P G + V+L L +NKI
Sbjct: 70 TRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRS 129
Query: 99 LRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPR- 157
+ LE LDL N I+ V+ F +K L+L+ NRIG L F GL R
Sbjct: 130 VEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS 189
Query: 158 LLRLNISGNIFSSLQPGVFDELPALKVVDL 187
LL L +S N + L F +LP L +DL
Sbjct: 190 LLTLRLSKNRITQLPVRAF-KLPRLTQLDL 218
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/104 (33%), Positives = 50/104 (48%)
Query: 84 NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 143
N L L N I+ L +G+F GLS + L L N + V G+ GL L +L LSNN
Sbjct: 235 NSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNS 294
Query: 144 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 187
I + + + +L L +S N + L EL +L V+ L
Sbjct: 295 IARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRL 338
Score = 45.4 bits (106), Expect = 4e-04
Identities = 28/76 (36%), Positives = 43/76 (56%)
Query: 91 LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 150
L+ N+I + +F GL+ LE L L+ N IS + GAF GL ++ L L N + + S
Sbjct: 218 LNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSG 277
Query: 151 TFQGLPRLLRLNISGN 166
+ GL L +L++S N
Sbjct: 278 SLYGLTALHQLHLSNN 293
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 103 bits (258), Expect = 8e-22
Identities = 209/913 (22%), Positives = 316/913 (34%), Gaps = 195/913 (21%)
Query: 323 SGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVA---NNRGDFRWPRTLAGITAYQS 379
SG+ C A G + E +AS C A + R WP+T G+ A
Sbjct: 2093 SGQCPCRPG-ALGRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLA--- 2148
Query: 380 CLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYT--NDITRVLYTFVL--MPI 435
+VP GA G A R CD A W D +C +++ +L L +
Sbjct: 2149 -------TVPCPRGALGA-AVRLCDEAQGWLEPDLFNCTSPAFRELSLLLDGLELNKTAL 2200
Query: 436 NASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGY----------VDQIKELVE 485
+ A LA +LR T + DV A+++ L + Q E
Sbjct: 2201 DTMEAKKLAQRLREVTGHTDHYFSQ-DVRVTARLLAHLLAFESHQQGFGLTATQDAHFNE 2259
Query: 486 VMVDMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVN-ARNVALE 544
++ S L+ + LW A + R G G A L H + + ARN+ L
Sbjct: 2260 NLLWAGSALLAPETGDLWAALGQ-----RAPGGSP--GSAGLVRHLEEYAATLARNMELT 2312
Query: 545 AY----LIKPHSYVGLT------------------CTAFQRREGGVPGTRPGSPGQNPPP 582
L+ P+ + + F+ ++ P T P Q+P P
Sbjct: 2313 YLNPMGLVTPNIMLSIDRMEHPSSPRGARRYPRYHSNLFRGQDAWDPHTHVLLPSQSPRP 2372
Query: 583 EPEPPADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPD-- 640
P V +S I+NS +S+ PP APP P
Sbjct: 2373 SPS----------------EVLPTSSSIENSTT-SSVVPPP----------APPEPEPGI 2405
Query: 641 CTLQLLVFRN-GRLFHSHSNTSRPGAA---GPGKRRGVATPVIFAGTSGCGVGNLTEPVA 696
+ LLV+R G L + R GA P V + +F G + G L P++
Sbjct: 2406 SIIILLVYRTLGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLR-GILESPIS 2464
Query: 697 VSLR--HWAEGAEPVAAWWSQEGPGEAGG-WTSEGCQLRSSQPNVSALHCQHLGNVAVLM 753
+ R A ++ + W G E G WT+ C+L + + C G VLM
Sbjct: 2465 LEFRLLQTANRSKAICVQWDPPGLAEQHGVWTARDCELVHRNGSHARCRCSRTGTFGVLM 2524
Query: 754 ELSAFPREVGGA---GAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWHMLLN 810
+ S R G H VV A L+L +L+ S++ + +G H N
Sbjct: 2525 DASPRERLEGDLELLAVFTHVVVAVSVAALVLTA-----AILLSLRSLKSNVRGIHA--N 2577
Query: 811 LCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPP 870
+ + + +F GI T+ Q+VC AV I LHY LST W+ V+ L++
Sbjct: 2578 VAAALGVAELLFLLGIHRTHNQLVCTAVAILLHYFFLSTFAWLFVQGLHLYR-------- 2629
Query: 871 PQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWL-VWRPSLGAFY 929
+ +P M ++ + G+P ++ G+ ++ Y + +CW+ V P + +F
Sbjct: 2630 -MQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGY-GNPDFCWISVHEPLIWSFA 2687
Query: 930 IPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDS 989
PV L++++ FL A +R S G+ T S L S
Sbjct: 2688 GPVVLVIVMNGTMFLLA----------------ARTSCSTGQREAKKT----SALTLRSS 2727
Query: 990 GSLLATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVV 1049
LL L A W G LAV+ L
Sbjct: 2728 FLLL---------------------------------LLVSASWLFGLLAVNHSIL---A 2751
Query: 1050 CSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPAAPHAPPRALPAAAEDGSPV 1109
L+ GL V C D RA+W C AA E+ P
Sbjct: 2752 FHYLHAGLCGLQGLAVLLLFCVLNADARAAWMPAC------------LGRKAAPEEARPA 2799
Query: 1110 FGEGPPSLKSSPSGSSGHPLALGPCKLTNLQLAQSQVCEAGAAAGGEGEPEPAGTRGNLA 1169
G GP G+ + L + L S V +A G + + + RG
Sbjct: 2800 PGLGP--------GAYNNTALFEESGLIRITLGASTVSSVSSARSGRTQDQDS-QRGRSY 2850
Query: 1170 HRHPNNVHHGRRA 1182
R V HG A
Sbjct: 2851 LRDNVLVRHGSAA 2863
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 101 bits (252), Expect = 4e-21
Identities = 82/267 (30%), Positives = 128/267 (47%), Gaps = 14/267 (5%)
Query: 89 LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTV---QPGAFLGLGELKRLDLSNNRIG 145
L L +N++T + +G F LS L+ LDLRNN IS AF GL L +L L N+I
Sbjct: 340 LNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIK 399
Query: 146 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 205
+T + F GL L L+++ N S+Q F + LK + L T L CDCHL+WLL W
Sbjct: 400 SITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTH-LKELILNTSSLLCDCHLKWLLQWL 458
Query: 206 QNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGAL--ELHTH-HLIPSLRQVVFQGD 262
+ + Q S + CA+P L Q++ ++ C+ L ++ TH I +LR G
Sbjct: 459 VDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETIIALR-----GM 513
Query: 263 RLPFQCSA-SYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVW 321
+ C+A S + W + + + + + TS L L ++
Sbjct: 514 NVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFT 573
Query: 322 ASGEWECTVSMAQG-NASKKVEIVVLE 347
G+++C V+ G N S+K ++ V E
Sbjct: 574 DEGKYQCIVTNHFGSNYSQKAKLTVNE 600
Score = 58.2 bits (139), Expect = 5e-08
Identities = 36/104 (34%), Positives = 52/104 (50%)
Query: 84 NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 143
N L L +N +T + G GL +L++L + N I + P A+ L LDLS N+
Sbjct: 263 NNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQ 322
Query: 144 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 187
+ L F GL L RLN+ N + + GVF L L+ +DL
Sbjct: 323 LTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 366
Score = 55.8 bits (133), Expect = 3e-07
Identities = 33/106 (31%), Positives = 61/106 (57%)
Query: 88 TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 147
+L + N I+ L++G+F GL+ +E+L+L +N ++ V G GL L++L +S N I +
Sbjct: 243 SLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERI 302
Query: 148 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLT 193
+ + ++ RL L++S N + L F L L+ ++LG +T
Sbjct: 303 SPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVT 348
Score = 53.1 bits (126), Expect = 2e-06
Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 1/118 (0%)
Query: 76 PPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELK 135
PP+ LP+ L L N+I + +F GL L L ++ N IS ++ GAF GL ++
Sbjct: 208 PPKIFKLPH-LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNME 266
Query: 136 RLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLT 193
L+L +N + + GL L +L +S N + P ++ L +DL LT
Sbjct: 267 ELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLT 324
Score = 51.6 bits (122), Expect = 5e-06
Identities = 59/189 (31%), Positives = 87/189 (46%), Gaps = 7/189 (3%)
Query: 3 AGGRRMRGAPARLLLPLLPWLLLLL-APEARGAPGC-PLSIRSCKCSGERPKGLSGGVPG 60
A G + AP +PLL L AP R G P S R + +
Sbjct: 37 AAGAGLCPAPCSCRIPLLDCSRRKLPAPSWRALSGLLPPDTAILDFSHNRLSNWNISLES 96
Query: 61 PARRRVVCSGGDLPEPPEPGLLPNGTVTLL-LSNNKITGLRNGSFLGLSLLEKLDLRNNI 119
+ V + +L E P G P +TLL L +N I + + LE LDL +NI
Sbjct: 97 QTLQEVKMNYNELTEIPYFGE-PTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNI 155
Query: 120 ISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGL-PRLLRLNISGNIFSSLQPGVFDE 178
IS ++ +F + +LK L+LSNNRI L + F L LL + ++ N S + P +F +
Sbjct: 156 ISEIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIF-K 213
Query: 179 LPALKVVDL 187
LP L+ ++L
Sbjct: 214 LPHLQFLEL 222
>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
Length = 3080
Score = 99.4 bits (246), Expect = 2e-20
Identities = 144/637 (22%), Positives = 244/637 (38%), Gaps = 103/637 (16%)
Query: 343 IVVLETSASYCPAERVANN-RGDFRWPRTLAGITAYQSCLQYP------FTSVPLGGGAP 395
+ V + C A+ A+ +G ++W T TA C++ F S+ + G
Sbjct: 2376 VAVKKLEPGNCKADETASKYKGTYKWLLTNPTETAQTRCIKNEDGNATRFCSISINTGK- 2434
Query: 396 GTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAA 455
+WE + C ++ + + I+ NA +A + E+
Sbjct: 2435 -----------SQWEKPKFKQCKLLQELPDKIVDLANITISDENAEDVAEHILNLINESP 2483
Query: 456 SFSDMMDVVYVAQMIQKFLGYVDQIK-ELVEVMVDMASNLMLVDEHLLWLAQREDKACSR 514
+ + V+++ + D+I L VM+ + N++L ++ A + +
Sbjct: 2484 ALGKEETKIIVSKISD--ISQCDEISMNLTHVMLQII-NVVLEKQNNS--ASDLHEISNE 2538
Query: 515 IVGALERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPG 574
I+ +ER G + Q ++ +AL A L H++ G+ + EG P G
Sbjct: 2539 ILRIIERTGHK-MEFSGQIANLTVAGLAL-AVLRGDHTFDGMAFSIHSYEEGTDPEIFLG 2596
Query: 575 SPGQNPPPEPEPPADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSLPAALA 634
NV + LASI LP SL +P +
Sbjct: 2597 ---------------------------NVPVGGI-------LASIYLPKSLTERIPLSNL 2622
Query: 635 PPVPPDCTLQLLVFRNGRLFHSHSNTSRPGAAGPGKRRGVATPVIFAGTSG-CGVGNLTE 693
T+ F LF + + T + + T V+ A S + NL +
Sbjct: 2623 Q------TILFNFFGQTSLFKTKNVT-----------KALTTYVVSASISDDMFIQNLAD 2665
Query: 694 PVAVSLRHWAEG---AEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVA 750
PV ++L+H + A+W E GGW S GC+++ + N + C HL +
Sbjct: 2666 PVVITLQHIGGNQNYGQVHCAFWDFENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFG 2725
Query: 751 VLMELSAFPREVGGAGAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGW--HML 808
VLM+LS + L + Y + + L ++TYI H RK + +L
Sbjct: 2726 VLMDLSRSTVDSVNEQI-LALITYTGCGISSIFLGVAVVTYIAFHK----LRKDYPAKIL 2780
Query: 809 LNLCFHIAMTSAVFAGGITLTNYQM--VCQAVGITLHYSSLSTLLWMGVKARVLHKELTW 866
+NLC + M + VF L+++Q VC + LHY L + WMG++A ++ L
Sbjct: 2781 INLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVK 2840
Query: 867 RAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLG 926
+ P+ +L+F L+ GIP I+ IT +V Y SP W
Sbjct: 2841 VF--------NIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTLSPTTPFCWIKDDS 2892
Query: 927 AFYIPV----ALILLITWIYFLCAGLRLRGPLAQNPK 959
FYI V LI L+ F ++L +Q K
Sbjct: 2893 IFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQK 2929
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 95.5 bits (236), Expect = 3e-19
Identities = 111/392 (28%), Positives = 171/392 (43%), Gaps = 48/392 (12%)
Query: 6 RRMRGAPARLLLPLL---PWLLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPGPA 62
+R RG R LL L+ W L + + GA GCP + + L VP A
Sbjct: 3 KRSRGPGRRCLLALVLFCAWGTLAVVAQKPGA-GCPSRCLCFRTTVRCMHLLLEAVPAVA 61
Query: 63 RRRVVCS-GGDLPEPPEPGLLPN--GTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNI 119
+ + + +PG TLLL+NN+I + +G+F L L+ L L N
Sbjct: 62 PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 121
Query: 120 ISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDEL 179
I ++ AF GL L++L L N+I L ++FQ LP+L RL + N + L PG F+ L
Sbjct: 122 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 181
Query: 180 PALKVVDLGTEFLTCDCHLRWLL----PWAQNRSLQLSEHTLCAYPSALHAQALGSLQEA 235
++K + L + L CDC + WL +A++ + Q + +C YP + +++ ++
Sbjct: 182 ESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAA--AICEYPRRIQGRSVATITPE 239
Query: 236 QLCCEGALELHTHHLIPSLRQ--VVFQGDRLPFQCSASYLGN-DTRIRWY--HNRAPVEG 290
+L CE I S Q V G+ + F C A GN I W +N ++
Sbjct: 240 ELNCE-------RPRITSEPQDADVTSGNTVYFTCRAE--GNPKPEIIWLRNNNELSMKT 290
Query: 291 DEQAGILLAESL-----------IHDC-------TFITSELTLSHIGVWASGEWECTVSM 332
D + +L +L I+ C T E+TL + G A + V
Sbjct: 291 DSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTF---VIQ 347
Query: 333 AQGNASKKVEIVVLETSASYCPAERVANNRGD 364
Q E V LE SA+ P R++ RGD
Sbjct: 348 PQNTEVLVGESVTLECSATGHPPPRISWTRGD 379
>gi|194306623 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 95.5 bits (236), Expect = 3e-19
Identities = 72/205 (35%), Positives = 93/205 (45%), Gaps = 35/205 (17%)
Query: 53 GLSGGVPGP-------ARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFL 105
G++G P P A + C+ +L E PE LP TL LS NKIT LR G+F
Sbjct: 15 GVAGSCPEPCACVDKYAHQFADCAYKELREVPEG--LPANVTTLSLSANKITVLRRGAFA 72
Query: 106 GLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNN----------------------- 142
++ + L L +N + TV+PGA L +LK LDLS+N
Sbjct: 73 DVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNH 132
Query: 143 -RIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWL 201
R+G L + LP L L I+ N +L PG FD L AL + L C C L WL
Sbjct: 133 NRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWL 192
Query: 202 LPWAQNRSLQLSE--HTLCAYPSAL 224
WA + + L E CA P AL
Sbjct: 193 QAWAASTRVSLPEPDSIACASPPAL 217
>gi|194306621 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 95.5 bits (236), Expect = 3e-19
Identities = 72/205 (35%), Positives = 93/205 (45%), Gaps = 35/205 (17%)
Query: 53 GLSGGVPGP-------ARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFL 105
G++G P P A + C+ +L E PE LP TL LS NKIT LR G+F
Sbjct: 15 GVAGSCPEPCACVDKYAHQFADCAYKELREVPEG--LPANVTTLSLSANKITVLRRGAFA 72
Query: 106 GLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNN----------------------- 142
++ + L L +N + TV+PGA L +LK LDLS+N
Sbjct: 73 DVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNH 132
Query: 143 -RIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWL 201
R+G L + LP L L I+ N +L PG FD L AL + L C C L WL
Sbjct: 133 NRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWL 192
Query: 202 LPWAQNRSLQLSE--HTLCAYPSAL 224
WA + + L E CA P AL
Sbjct: 193 QAWAASTRVSLPEPDSIACASPPAL 217
>gi|39930401 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 95.5 bits (236), Expect = 3e-19
Identities = 72/205 (35%), Positives = 93/205 (45%), Gaps = 35/205 (17%)
Query: 53 GLSGGVPGP-------ARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFL 105
G++G P P A + C+ +L E PE LP TL LS NKIT LR G+F
Sbjct: 15 GVAGSCPEPCACVDKYAHQFADCAYKELREVPEG--LPANVTTLSLSANKITVLRRGAFA 72
Query: 106 GLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNN----------------------- 142
++ + L L +N + TV+PGA L +LK LDLS+N
Sbjct: 73 DVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNH 132
Query: 143 -RIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWL 201
R+G L + LP L L I+ N +L PG FD L AL + L C C L WL
Sbjct: 133 NRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWL 192
Query: 202 LPWAQNRSLQLSE--HTLCAYPSAL 224
WA + + L E CA P AL
Sbjct: 193 QAWAASTRVSLPEPDSIACASPPAL 217
>gi|194306618 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 95.5 bits (236), Expect = 3e-19
Identities = 72/205 (35%), Positives = 93/205 (45%), Gaps = 35/205 (17%)
Query: 53 GLSGGVPGP-------ARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFL 105
G++G P P A + C+ +L E PE LP TL LS NKIT LR G+F
Sbjct: 15 GVAGSCPEPCACVDKYAHQFADCAYKELREVPEG--LPANVTTLSLSANKITVLRRGAFA 72
Query: 106 GLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNN----------------------- 142
++ + L L +N + TV+PGA L +LK LDLS+N
Sbjct: 73 DVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNH 132
Query: 143 -RIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWL 201
R+G L + LP L L I+ N +L PG FD L AL + L C C L WL
Sbjct: 133 NRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWL 192
Query: 202 LPWAQNRSLQLSE--HTLCAYPSAL 224
WA + + L E CA P AL
Sbjct: 193 QAWAASTRVSLPEPDSIACASPPAL 217
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 95.1 bits (235), Expect = 4e-19
Identities = 73/256 (28%), Positives = 120/256 (46%), Gaps = 22/256 (8%)
Query: 691 LTEPVAV--SLRHWAEGAEPVAAWWSQE-GPGEAGGWTSEGCQLRSSQPNVSALHCQHLG 747
L PV V +L E +PV +W+ G GGW++ GC+L S A C H
Sbjct: 2390 LERPVLVEFALLEVEERTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTA 2449
Query: 748 NVAVLMELSAFPREVGGAGAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWHM 807
+ AVLM++S R G L V Y A + L L A ++ ++L S +R+ R H
Sbjct: 2450 SFAVLMDIS---RRENGEVLPLKIVTY---AAVSLSLAALLVAFVL-LSLVRMLRSNLHS 2502
Query: 808 L-LNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTW 866
+ +L + ++ VF GI T +C V I LHY +ST W V++ +++ LT
Sbjct: 2503 IHKHLAVALFLSQLVFVIGINQTENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLT- 2561
Query: 867 RAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSL- 925
+ PM +Y++ GIP I+ G+ ++ Y + +CWL + +L
Sbjct: 2562 --------EVRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGY-GNPDFCWLSLQDTLI 2612
Query: 926 GAFYIPVALILLITWI 941
+F P+ +++I +
Sbjct: 2613 WSFAGPIGAVIIINTV 2628
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 93.6 bits (231), Expect = 1e-18
Identities = 52/151 (34%), Positives = 82/151 (54%), Gaps = 1/151 (0%)
Query: 91 LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 150
LSNNKI +R G+F G + +++L L N + TV F GL LK L L +N IGC++++
Sbjct: 564 LSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSND 623
Query: 151 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 210
TF GL + L++ N +++ PG F L +L ++L + C+CHL WL W + R +
Sbjct: 624 TFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRI 683
Query: 211 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 241
+S + C P L + + C+G
Sbjct: 684 -VSGNPRCQKPFFLKEIPIQDVAIQDFTCDG 713
Score = 84.7 bits (208), Expect = 5e-16
Identities = 57/201 (28%), Positives = 88/201 (43%), Gaps = 27/201 (13%)
Query: 66 VVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQP 125
V C G L E P LP G V + L N I + G+F L+++D+ N IS + P
Sbjct: 291 VDCRGKGLMEIPAN--LPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAP 348
Query: 126 GAFLGLGELKRLDL------------------------SNNRIGCLTSETFQGLPRLLRL 161
AF GL L L L + N+I CL TFQ L L L
Sbjct: 349 DAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLL 408
Query: 162 NISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYP 221
++ N ++ G+F L +++ + L CDCHL+WL + Q+ ++ S C+ P
Sbjct: 409 SLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETS-GARCSSP 467
Query: 222 SALHAQALGSLQEAQLCCEGA 242
L + + ++ + C G+
Sbjct: 468 RRLANKRISQIKSKKFRCSGS 488
Score = 83.6 bits (205), Expect = 1e-15
Identities = 48/151 (31%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Query: 89 LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 148
L L+ NK+ L F L +LDL N I + AF G+ ++K L L NN I C+
Sbjct: 114 LRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIE 173
Query: 149 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 208
F+ L L L ++ N S + F+ +P ++ + L + L CDCHL WL W + R
Sbjct: 174 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQR 233
Query: 209 SLQLSEHTLCAYPSALHAQALGSLQEAQLCC 239
+ + TLC P L + +Q+ + C
Sbjct: 234 R-TVGQFTLCMAPVHLRGFNVADVQKKEYVC 263
Score = 79.0 bits (193), Expect = 3e-14
Identities = 52/168 (30%), Positives = 78/168 (46%), Gaps = 2/168 (1%)
Query: 79 PGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLD 138
P +P L L N +T + L L +DL NN IS + F + L L
Sbjct: 747 PRGMPKDVTELYLEGNHLTAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLI 805
Query: 139 LSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHL 198
LS NR+ C+ F GL L L + GN SS+ G F++L +L + LGT L CDC L
Sbjct: 806 LSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSL 865
Query: 199 RWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELH 246
RWL W + + C+ P + + L + + C+G ++++
Sbjct: 866 RWLSEWVK-AGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDIN 912
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 92.4 bits (228), Expect = 3e-18
Identities = 98/362 (27%), Positives = 147/362 (40%), Gaps = 42/362 (11%)
Query: 19 LLPWLLLLLAPEARGAPG-CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLPEPP 77
LLP LLLLL A G P C + +C R + + G+P P + + ++
Sbjct: 8 LLPLLLLLLPLRAAGCPAACRCYSATVECGALRLRVVPLGIP-PGTQTLFLQDNNIARLE 66
Query: 78 EPGLLPNGTVT-LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKR 136
L P + L L NN + L G+F L +L L +N + ++ GAF+GL +L+
Sbjct: 67 PGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRV 126
Query: 137 LDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFL---- 192
L L+ N++ L TF LPRL L++ N L+ L +L ++DL L
Sbjct: 127 LYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTIS 186
Query: 193 --------------------TCDCHLRWLLPWAQNRSLQL----SEHTLCAYPSALHAQA 228
CDC L WL W + +L +CA P L Q+
Sbjct: 187 REALQPLASLQVLRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKIMCAEPPRLALQS 246
Query: 229 LGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPV 288
L + + L C + H + L G+ L C AS + W P
Sbjct: 247 LLDVSHSSLIC---IPPSVH--VQPLELTANLGEDLRVACQASGYPQPL-VTWRKVPQPR 300
Query: 289 EGDEQAGILLAESLI----HDCTFITS-ELTLSHIGVWASGEWECTVSMAQGNASKKVEI 343
EG +A L L+ H + S L LS+I + +G++EC S A G A +
Sbjct: 301 EGRPRAQAQLEGGLLGLGGHSASDTGSGMLFLSNITLAHAGKYECEASNAGGAARVPFRL 360
Query: 344 VV 345
+V
Sbjct: 361 LV 362
>gi|61966761 leucine rich repeat containing 26 [Homo sapiens]
Length = 334
Score = 90.5 bits (223), Expect = 1e-17
Identities = 82/253 (32%), Positives = 106/253 (41%), Gaps = 51/253 (20%)
Query: 15 LLLPLLPW-----LLLLLAPEAR-GAPGCPLSIRSCKCSGERPKGLSGGVPGPARRRVVC 68
LLL L PW + +P GAP CP C C P GL+ C
Sbjct: 15 LLLLLSPWPVWAQVSATASPSGSLGAPDCP---EVCTCV---PGGLAS-----------C 57
Query: 69 SGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAF 128
S LP P PGL LLL +N++ L G+F G L++LDLR N + +V AF
Sbjct: 58 SALSLPAVP-PGLSLR-LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAF 115
Query: 129 LGLGELKRLDLSNNRIGCLTSETFQ------------------------GLPRLLRLNIS 164
GLG L+ LDLS N++ L TF LP L L++
Sbjct: 116 WGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQ 175
Query: 165 GNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLS--EHTLCAYPS 222
N ++L PG+ LPAL + L C C LR L W + L S E LC +P
Sbjct: 176 DNELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPG 235
Query: 223 ALHAQALGSLQEA 235
L L + +A
Sbjct: 236 RLTLSPLTAFSDA 248
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 90.5 bits (223), Expect = 1e-17
Identities = 49/154 (31%), Positives = 82/154 (53%), Gaps = 1/154 (0%)
Query: 91 LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 150
LSNNK++ + +G+F G + + +L L N + +++ G F GL L+ L L NNRI C+ ++
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631
Query: 151 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 210
+F GL + L++ N +++ PG FD L +L ++L C+C L WL W + R +
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKI 691
Query: 211 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 244
++ + C P L L + CE E
Sbjct: 692 -VTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQE 724
Score = 87.8 bits (216), Expect = 6e-17
Identities = 57/176 (32%), Positives = 85/176 (48%), Gaps = 4/176 (2%)
Query: 66 VVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQP 125
V CS L P+ +P L L N+ T L G L+ +DL NN IS++
Sbjct: 745 VRCSNKHLRALPKG--IPKNVTELYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSN 801
Query: 126 GAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVV 185
+F + +L L LS N + C+ FQGL L L++ GN S+LQ G+F ++ +L +
Sbjct: 802 SSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Query: 186 DLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 241
+G L CDCHLRWL W + + CA P + + L + + C+G
Sbjct: 862 AIGANPLYCDCHLRWLSSWVKT-GYKEPGIARCAGPQDMEGKLLLTTPAKKFECQG 916
Score = 87.4 bits (215), Expect = 8e-17
Identities = 73/268 (27%), Positives = 101/268 (37%), Gaps = 69/268 (25%)
Query: 22 WLLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLPEPPEPGL 81
WLLL A GA CP C C+G V C G L P+
Sbjct: 19 WLLLWAAAWRLGASACPAL---CTCTGTT---------------VDCHGTGLQAIPKN-- 58
Query: 82 LPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRL---- 137
+P T L L+ N IT + F GL L L L N I V+ GAF + EL+RL
Sbjct: 59 IPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNR 118
Query: 138 --------------------DLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGV-- 175
DLS N I + + F+G L L + N S ++ G
Sbjct: 119 NQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFR 178
Query: 176 ----------------------FDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLS 213
F+ +P L+ L + L CDCHL WL W + R +
Sbjct: 179 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRP-TIG 237
Query: 214 EHTLCAYPSALHAQALGSLQEAQLCCEG 241
T C+ P++L + +Q+++ C G
Sbjct: 238 LFTQCSGPASLRGLNVAEVQKSEFSCSG 265
Score = 82.4 bits (202), Expect = 3e-15
Identities = 63/221 (28%), Positives = 94/221 (42%), Gaps = 12/221 (5%)
Query: 30 EARGAPGCPLSIRSCK-----------CSGERPKGLSGGVPGPARRRVVCSGGDLPEPPE 78
EA P C LS SC C G+ + +P + G PP
Sbjct: 268 EAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPG 327
Query: 79 PGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLD 138
+ LSNN+I + +F GL L L L N I+ + G F GL L+ L
Sbjct: 328 AFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLL 387
Query: 139 LSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHL 198
L+ N+I C+ + FQ L L L++ N SL G F L A++ + L CDC+L
Sbjct: 388 LNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNL 447
Query: 199 RWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 239
+WL + + ++ S CA P L + +G ++ + C
Sbjct: 448 KWLADFLRTNPIETS-GARCASPRRLANKRIGQIKSKKFRC 487
Score = 50.1 bits (118), Expect = 1e-05
Identities = 28/63 (44%), Positives = 37/63 (58%)
Query: 84 NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 143
+G TL+L NN+I+ + N SF GL + L L +N I+TV PGAF L L L+L N
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Query: 144 IGC 146
C
Sbjct: 673 FNC 675
>gi|88702793 slit-like 2 [Homo sapiens]
Length = 673
Score = 88.2 bits (217), Expect = 5e-17
Identities = 84/226 (37%), Positives = 105/226 (46%), Gaps = 33/226 (14%)
Query: 15 LLLPLLPWLLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLP 74
LLLPLL LLL L P G GCP C+CS + V C+
Sbjct: 7 LLLPLL--LLLALGP---GVQGCP---SGCQCSQPQT--------------VFCTARQGT 44
Query: 75 EPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGEL 134
P +P TV L + N IT L GSF GL L+ LDL N I+++ G F L L
Sbjct: 45 TVPRD--VPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANL 102
Query: 135 KRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTC 194
LDL+ NR+ +T+ETF+GL RL RL + N +QPG FD L L E
Sbjct: 103 SNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRL------LELKLQ 156
Query: 195 DCHLRWLLPWAQNR--SLQLSEHTLCAY-PSALHAQALGSLQEAQL 237
D LR L P R L LS ++L A P L + +L+ A L
Sbjct: 157 DNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGL 202
Score = 63.9 bits (154), Expect = 1e-09
Identities = 58/200 (29%), Positives = 83/200 (41%), Gaps = 8/200 (4%)
Query: 78 EPGLLPNGTVTLL-LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKR 136
EPG+L V L L+ + L G F L L LD+ +N + V P GL L R
Sbjct: 185 EPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPP-VIRGLRGLTR 243
Query: 137 LDLSNN-RIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 195
L L+ N RI L E GL L L++S +L + P L+++ C
Sbjct: 244 LRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCV 303
Query: 196 CHLRWLLPWAQNRSLQLS--EHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPS 253
C L W PW + + L+ E T C +P + L L A C T +P+
Sbjct: 304 CPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTAT---VPT 360
Query: 254 LRQVVFQGDRLPFQCSASYL 273
R VV + L + ++L
Sbjct: 361 TRPVVREPTALSSSLAPTWL 380
>gi|21281681 leucine-rich repeat LGI family, member 3 [Homo sapiens]
Length = 548
Score = 87.4 bits (215), Expect = 8e-17
Identities = 67/236 (28%), Positives = 102/236 (43%), Gaps = 21/236 (8%)
Query: 5 GRRMRGAPARLLLPLLPW-LLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPGPAR 63
G R RG P LL L L+L A+ P P SC C+ R
Sbjct: 3 GLRARGGPGPGLLALSALGFCLMLQVSAKRPPKTPPCPPSCSCT---------------R 47
Query: 64 RRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTV 123
C + P LP+ ++L L N + +++G+F L LL+ L L +N + +
Sbjct: 48 DTAFC----VDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLI 103
Query: 124 QPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALK 183
AF GL L+ L + NN I L+ TF+GL L L+++ N +L +F L L
Sbjct: 104 GDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILN 163
Query: 184 VVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 239
+DL L CDC ++WL+ W + + ++ CA P + L + C
Sbjct: 164 DLDLRGNSLNCDCKVKWLVEWLAHTNTTVAP-IYCASPPRFQEHKVQDLPLREFDC 218
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 85.9 bits (211), Expect = 2e-16
Identities = 52/165 (31%), Positives = 78/165 (47%), Gaps = 5/165 (3%)
Query: 89 LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 148
L L+ N + FLG + L +LDL N I + AF G ++K L L N+I C+
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167
Query: 149 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 208
F+ L L L ++ N + L F+ +P L+ L + L CDCHL WL W + R
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQR 227
Query: 209 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPS 253
++ +T C PS L + +Q+ + C G H + PS
Sbjct: 228 P-RVGLYTQCMGPSHLRGHNVAEVQKREFVCSG----HQSFMAPS 267
Score = 82.8 bits (203), Expect = 2e-15
Identities = 43/119 (36%), Positives = 69/119 (57%)
Query: 92 SNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSET 151
SNNKIT + G+F G S + ++ L +N + VQ F GL LK L L +NRI C+ +++
Sbjct: 566 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDS 625
Query: 152 FQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 210
F GL + L++ N +++ PG FD L +L ++L C+C+L WL W + + +
Sbjct: 626 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRI 684
Score = 81.6 bits (200), Expect = 5e-15
Identities = 55/181 (30%), Positives = 87/181 (48%), Gaps = 4/181 (2%)
Query: 66 VVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQP 125
V CS L P+ +P L L N+ T L L +DL NN IST+
Sbjct: 738 VRCSNKGLKVLPKG--IPRDVTELYLDGNQFT-LVPKELSNYKHLTLIDLSNNRISTLSN 794
Query: 126 GAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVV 185
+F + +L L LS NR+ C+ TF GL L L++ GN S + G F++L AL +
Sbjct: 795 QSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHL 854
Query: 186 DLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALEL 245
+G L CDC+++WL W ++ + CA P + + L + + C+G +++
Sbjct: 855 AIGANPLYCDCNMQWLSDWVKSEYKE-PGIARCAGPGEMADKLLLTTPSKKFTCQGPVDV 913
Query: 246 H 246
+
Sbjct: 914 N 914
Score = 80.1 bits (196), Expect = 1e-14
Identities = 48/149 (32%), Positives = 73/149 (48%), Gaps = 1/149 (0%)
Query: 91 LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 150
LSNN+I+ L +F GL L L L N I+ + F GL L+ L L+ N+I CL +
Sbjct: 331 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 390
Query: 151 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 210
FQ L L L++ N ++ G F L A++ + L CDCHL+WL + +
Sbjct: 391 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPI 450
Query: 211 QLSEHTLCAYPSALHAQALGSLQEAQLCC 239
+ S C P L + +G ++ + C
Sbjct: 451 ETS-GARCTSPRRLANKRIGQIKSKKFRC 478
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/108 (35%), Positives = 56/108 (51%), Gaps = 4/108 (3%)
Query: 88 TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 147
TL+L +N+IT + N SF+GLS + L L +N I+TV PGAF L L L+L N C
Sbjct: 610 TLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCN 669
Query: 148 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 195
+ G + ++GN +P E+P + D+ + TCD
Sbjct: 670 CYLAWLGEWLRKKRIVTGNP-RCQKPYFLKEIP---IQDVAIQDFTCD 713
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 85.5 bits (210), Expect = 3e-16
Identities = 125/521 (23%), Positives = 196/521 (37%), Gaps = 92/521 (17%)
Query: 567 GVPGTR--PGSPGQNPPPEPEPPADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPS 624
G P T GSPG+ P PP R P+ S S+ + +V
Sbjct: 772 GKPATSGAAGSPGRGRGPGTVPPGPGHSHQRLLPADPDES--SYFVIGAV---------- 819
Query: 625 LFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNTSRPGAAGPGKRRGVATPVIFAGTS 684
L+ +L L PP PP ++ + T RP P A P+I S
Sbjct: 820 LYRTLGLILPPPRPPLAVTSRVM----------TVTVRPPTQPP------AEPLITVELS 863
Query: 685 GCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQ 744
+ T+P A+W +G W +E CQ +Q + CQ
Sbjct: 864 YI-INGTTDPHC-------------ASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQ 909
Query: 745 HLGNVAVLMELSAFPRE--VGGAGAGLHPVVYPCTA-----LLLLCLFATIITYILNHSS 797
HL AVL + P++ + AG+ P+V C L LL ++A +I + S
Sbjct: 910 HLSTFAVLAQP---PKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERS 966
Query: 798 IRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKA 857
I +LLN C I ++ + G + + VC LH+ LS+ W+ +A
Sbjct: 967 I--------ILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEA 1018
Query: 858 RVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYC 917
W++ G + T RF + G+P ++ ++ S YC
Sbjct: 1019 --------WQSYLAVIG--RMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYC 1068
Query: 918 WLVWRPS-LGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGS 976
WL L AF P A+I+L+ + + +L +A++ + S+ E +
Sbjct: 1069 WLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKL---MARDGISDKSKKQRAGSERCPWA 1125
Query: 977 TRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACG 1036
+ L + LL++ SAR SL+S V L L T W
Sbjct: 1126 SLLLPCSACGAVPSPLLSSASARNAMA-------SLWSSCVVLPLLALT-------WMSA 1171
Query: 1037 ALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVR 1077
LA++ R V+ L+ V SA G + HC RR+V+
Sbjct: 1172 VLAMTDR--RSVLFQALFAVFNSAQGFVITAVHCFLRREVQ 1210
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 85.5 bits (210), Expect = 3e-16
Identities = 91/402 (22%), Positives = 154/402 (38%), Gaps = 69/402 (17%)
Query: 691 LTEPVAVSLRHWAEGAE---PVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLG 747
L +PV +++H + E P ++WS G W+++GC+L ++ + C HL
Sbjct: 796 LADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLT 855
Query: 748 NVAVLMELSAFPREVGGAGAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWHM 807
N AVLM L + + L L+CL I T+ ++ R H
Sbjct: 856 NFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCF-FRGLQSDRNTIHK 914
Query: 808 LLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWR 867
NLC + + +F GI T+ + C LH+ L+ WM ++ L+ L
Sbjct: 915 --NLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLV-- 970
Query: 868 APPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWL------VW 921
+ S FYL+ G+P +I ++AAV+ +Y CWL +W
Sbjct: 971 -------EVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSY-GTDKVCWLRLDTYFIW 1022
Query: 922 RPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRG 981
+F P LI+++ I+ A ++
Sbjct: 1023 -----SFIGPATLIIMLNVIFLGIALYKM----------------------------FHH 1049
Query: 982 SGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVS 1041
+ L +SG L ED V +GA+ L L WA G + ++
Sbjct: 1050 TAILKPESGCLDNINY---------EDNRPFIKSWV-IGAIALLCLLGLT-WAFGLMYIN 1098
Query: 1042 QRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRAC 1083
+ V+ + L+ + S G+F+F HC ++ VR + C
Sbjct: 1099 E---STVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKC 1137
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 83.2 bits (204), Expect = 2e-15
Identities = 69/280 (24%), Positives = 119/280 (42%), Gaps = 32/280 (11%)
Query: 691 LTEPVAVSLR--HWAEGAEPVAAWWSQEG-PGEAGGWTSEGCQLRSSQPNVSALHCQHLG 747
L +PV V R E +P+ +W+ GGW++ GC++ + + C H+
Sbjct: 2298 LDKPVTVQFRLLETEERTKPICVFWNHSILVSGTGGWSARGCEVVFRNESHVSCQCNHMT 2357
Query: 748 NVAVLMELSAFPREVGGAGAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWH- 806
+ AVLM++S R G L + Y + L L T L +R+ R H
Sbjct: 2358 SFAVLMDVS---RRENGEILPLKTLTYVALGVTLAALLLTFFFLTL----LRILRSNQHG 2410
Query: 807 MLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTW 866
+ NL + + VF GI + C + I LH+ L T W ++A L++ LT
Sbjct: 2411 IRRNLTAALGLAQLVFLLGINQADLPFACTVIAILLHFLYLCTFSWALLEALHLYRALT- 2469
Query: 867 RAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWL-VWRPSL 925
+ PM +Y++ G+P I G+ ++ Y + +CWL ++ +
Sbjct: 2470 --------EVRDVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGY-GNPDFCWLSIYDTLI 2520
Query: 926 GAFYIPVAL-ILLITWIYFLCA---------GLRLRGPLA 955
+F PVA + + ++Y L A G +GP++
Sbjct: 2521 WSFAGPVAFAVSMSVFLYILAARASCAAQRQGFEKKGPVS 2560
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 83.2 bits (204), Expect = 2e-15
Identities = 83/362 (22%), Positives = 138/362 (38%), Gaps = 65/362 (17%)
Query: 722 GGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVG-GAGAGLHPVVYPCTALL 780
G W++ GC L S C HL N A+LM++ P E+ G L + Y +L
Sbjct: 520 GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQV--VPLELARGHQVALSSISYVGCSLS 577
Query: 781 LLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGI 840
+LCL AT++T+ + S + + +H+ NL F + + + L CQ + +
Sbjct: 578 VLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAV 637
Query: 841 TLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAG-GIPLIIC 899
LHY LS WM V+ L+ + + R+Y G G PL+IC
Sbjct: 638 LLHYFFLSAFAWMLVEGLHLYSMVI----------KVFGSEDSKHRYYYGMGWGFPLLIC 687
Query: 900 GITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPK 959
I+ + + +Y S CWL ++ AL +++ I L A R+ ++ +
Sbjct: 688 IISLSFAMDSY-GTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQISAD-- 744
Query: 960 AGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQL 1019
+ ++ G + +A +GT
Sbjct: 745 ----------------NYKIHGDPSAFKLTAKAVAVLLPILGT----------------- 771
Query: 1020 GALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRAS 1079
W G LAV+ VV ++ S GLF+F HC +VRA+
Sbjct: 772 ------------SWVFGVLAVNG---CAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAA 816
Query: 1080 WR 1081
++
Sbjct: 817 FK 818
>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
Length = 995
Score = 83.2 bits (204), Expect = 2e-15
Identities = 115/509 (22%), Positives = 192/509 (37%), Gaps = 114/509 (22%)
Query: 603 VSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNTSR 662
VSL + +NS+ +I LP SL ++LPA + +Q F LF S
Sbjct: 453 VSLETQAPENSIG--TITLPSSLMNNLPAH---DMELASRVQFNFFETPALFQDPSL--- 504
Query: 663 PGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAA---WWSQEGPG 719
+ + + VI + + V NLT V V+L+H + + +W G
Sbjct: 505 -------ENLSLISYVISSSVANLTVRNLTRNVTVTLKHINPSQDELTVRCVFWDLGRNG 557
Query: 720 EAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMEL---SAFPREVGGAGAGLHPVVYPC 776
GGW+ GC ++ + N + C HL + VL++L S P ++ L + Y
Sbjct: 558 GRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQM----MALTFITYIG 613
Query: 777 TALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFA--GGITLTNYQMV 834
L + L T++TYI IR +L+ LC + + + VF I L Q +
Sbjct: 614 CGLSSIFLSVTLVTYIA-FEKIRRDYPS-KILIQLCAALLLLNLVFLLDSWIALYKMQGL 671
Query: 835 CQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPT--PSPMLRFYLIAG 892
C +V + LHY L + WMG++A ++ L T +L+F ++
Sbjct: 672 CISVAVFLHYFLLVSFTWMGLEAFHMYLALV----------KVFNTYIRKYILKFCIVGW 721
Query: 893 GIPLIICGITAAVNIHNY--------RDHSP--YCWLVWRPSLGAFYIPV----ALILLI 938
G+P ++ I ++ NY + SP +CW+ + FYI V +I L+
Sbjct: 722 GVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI---NNNAVFYITVVGYFCVIFLL 778
Query: 939 TWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSA 998
F+ ++L + + S++ + G T L G
Sbjct: 779 NVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLG----------------- 821
Query: 999 RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLP-RVVCSCLYGVA 1057
+T F + A W P V L+ +
Sbjct: 822 ------------------------ITWGFAFFA------------WGPVNVTFMYLFAIF 845
Query: 1058 ASALGLFVFTHHCARRRDVRASWR--ACC 1084
+ G F+F +C + +VR WR CC
Sbjct: 846 NTLQGFFIFIFYCVAKENVRKQWRRYLCC 874
>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
Length = 1003
Score = 83.2 bits (204), Expect = 2e-15
Identities = 115/509 (22%), Positives = 192/509 (37%), Gaps = 114/509 (22%)
Query: 603 VSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNTSR 662
VSL + +NS+ +I LP SL ++LPA + +Q F LF S
Sbjct: 461 VSLETQAPENSIG--TITLPSSLMNNLPAH---DMELASRVQFNFFETPALFQDPSL--- 512
Query: 663 PGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAA---WWSQEGPG 719
+ + + VI + + V NLT V V+L+H + + +W G
Sbjct: 513 -------ENLSLISYVISSSVANLTVRNLTRNVTVTLKHINPSQDELTVRCVFWDLGRNG 565
Query: 720 EAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMEL---SAFPREVGGAGAGLHPVVYPC 776
GGW+ GC ++ + N + C HL + VL++L S P ++ L + Y
Sbjct: 566 GRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQM----MALTFITYIG 621
Query: 777 TALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFA--GGITLTNYQMV 834
L + L T++TYI IR +L+ LC + + + VF I L Q +
Sbjct: 622 CGLSSIFLSVTLVTYIA-FEKIRRDYPS-KILIQLCAALLLLNLVFLLDSWIALYKMQGL 679
Query: 835 CQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPT--PSPMLRFYLIAG 892
C +V + LHY L + WMG++A ++ L T +L+F ++
Sbjct: 680 CISVAVFLHYFLLVSFTWMGLEAFHMYLALV----------KVFNTYIRKYILKFCIVGW 729
Query: 893 GIPLIICGITAAVNIHNY--------RDHSP--YCWLVWRPSLGAFYIPV----ALILLI 938
G+P ++ I ++ NY + SP +CW+ + FYI V +I L+
Sbjct: 730 GVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI---NNNAVFYITVVGYFCVIFLL 786
Query: 939 TWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSA 998
F+ ++L + + S++ + G T L G
Sbjct: 787 NVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLG----------------- 829
Query: 999 RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLP-RVVCSCLYGVA 1057
+T F + A W P V L+ +
Sbjct: 830 ------------------------ITWGFAFFA------------WGPVNVTFMYLFAIF 853
Query: 1058 ASALGLFVFTHHCARRRDVRASWR--ACC 1084
+ G F+F +C + +VR WR CC
Sbjct: 854 NTLQGFFIFIFYCVAKENVRKQWRRYLCC 882
>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
Length = 1017
Score = 83.2 bits (204), Expect = 2e-15
Identities = 115/509 (22%), Positives = 192/509 (37%), Gaps = 114/509 (22%)
Query: 603 VSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNTSR 662
VSL + +NS+ +I LP SL ++LPA + +Q F LF S
Sbjct: 475 VSLETQAPENSIG--TITLPSSLMNNLPAH---DMELASRVQFNFFETPALFQDPSL--- 526
Query: 663 PGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAA---WWSQEGPG 719
+ + + VI + + V NLT V V+L+H + + +W G
Sbjct: 527 -------ENLSLISYVISSSVANLTVRNLTRNVTVTLKHINPSQDELTVRCVFWDLGRNG 579
Query: 720 EAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMEL---SAFPREVGGAGAGLHPVVYPC 776
GGW+ GC ++ + N + C HL + VL++L S P ++ L + Y
Sbjct: 580 GRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQM----MALTFITYIG 635
Query: 777 TALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFA--GGITLTNYQMV 834
L + L T++TYI IR +L+ LC + + + VF I L Q +
Sbjct: 636 CGLSSIFLSVTLVTYIA-FEKIRRDYPS-KILIQLCAALLLLNLVFLLDSWIALYKMQGL 693
Query: 835 CQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPT--PSPMLRFYLIAG 892
C +V + LHY L + WMG++A ++ L T +L+F ++
Sbjct: 694 CISVAVFLHYFLLVSFTWMGLEAFHMYLALV----------KVFNTYIRKYILKFCIVGW 743
Query: 893 GIPLIICGITAAVNIHNY--------RDHSP--YCWLVWRPSLGAFYIPV----ALILLI 938
G+P ++ I ++ NY + SP +CW+ + FYI V +I L+
Sbjct: 744 GVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI---NNNAVFYITVVGYFCVIFLL 800
Query: 939 TWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSA 998
F+ ++L + + S++ + G T L G
Sbjct: 801 NVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLG----------------- 843
Query: 999 RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLP-RVVCSCLYGVA 1057
+T F + A W P V L+ +
Sbjct: 844 ------------------------ITWGFAFFA------------WGPVNVTFMYLFAIF 867
Query: 1058 ASALGLFVFTHHCARRRDVRASWR--ACC 1084
+ G F+F +C + +VR WR CC
Sbjct: 868 NTLQGFFIFIFYCVAKENVRKQWRRYLCC 896
>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
Length = 1014
Score = 83.2 bits (204), Expect = 2e-15
Identities = 115/509 (22%), Positives = 192/509 (37%), Gaps = 114/509 (22%)
Query: 603 VSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNTSR 662
VSL + +NS+ +I LP SL ++LPA + +Q F LF S
Sbjct: 472 VSLETQAPENSIG--TITLPSSLMNNLPAH---DMELASRVQFNFFETPALFQDPSL--- 523
Query: 663 PGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAA---WWSQEGPG 719
+ + + VI + + V NLT V V+L+H + + +W G
Sbjct: 524 -------ENLSLISYVISSSVANLTVRNLTRNVTVTLKHINPSQDELTVRCVFWDLGRNG 576
Query: 720 EAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMEL---SAFPREVGGAGAGLHPVVYPC 776
GGW+ GC ++ + N + C HL + VL++L S P ++ L + Y
Sbjct: 577 GRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQM----MALTFITYIG 632
Query: 777 TALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFA--GGITLTNYQMV 834
L + L T++TYI IR +L+ LC + + + VF I L Q +
Sbjct: 633 CGLSSIFLSVTLVTYIA-FEKIRRDYPS-KILIQLCAALLLLNLVFLLDSWIALYKMQGL 690
Query: 835 CQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPT--PSPMLRFYLIAG 892
C +V + LHY L + WMG++A ++ L T +L+F ++
Sbjct: 691 CISVAVFLHYFLLVSFTWMGLEAFHMYLALV----------KVFNTYIRKYILKFCIVGW 740
Query: 893 GIPLIICGITAAVNIHNY--------RDHSP--YCWLVWRPSLGAFYIPV----ALILLI 938
G+P ++ I ++ NY + SP +CW+ + FYI V +I L+
Sbjct: 741 GVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI---NNNAVFYITVVGYFCVIFLL 797
Query: 939 TWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSA 998
F+ ++L + + S++ + G T L G
Sbjct: 798 NVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLG----------------- 840
Query: 999 RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLP-RVVCSCLYGVA 1057
+T F + A W P V L+ +
Sbjct: 841 ------------------------ITWGFAFFA------------WGPVNVTFMYLFAIF 864
Query: 1058 ASALGLFVFTHHCARRRDVRASWR--ACC 1084
+ G F+F +C + +VR WR CC
Sbjct: 865 NTLQGFFIFIFYCVAKENVRKQWRRYLCC 893
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,602,164
Number of Sequences: 37866
Number of extensions: 3303093
Number of successful extensions: 20830
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 245
Number of HSP's successfully gapped in prelim test: 322
Number of HSP's that attempted gapping in prelim test: 17755
Number of HSP's gapped (non-prelim): 2768
length of query: 1338
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1224
effective length of database: 13,930,794
effective search space: 17051291856
effective search space used: 17051291856
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.