BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194272176 phospholipase D1 isoform b [Homo sapiens] (1036 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194272176 phospholipase D1 isoform b [Homo sapiens] 2111 0.0 gi|4505873 phospholipase D1 isoform a [Homo sapiens] 2090 0.0 gi|156564407 phospholipase D2 [Homo sapiens] 546 e-155 gi|7661880 centaurin beta1 [Homo sapiens] 35 0.48 gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 34 0.82 gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 34 0.82 gi|109150427 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-l... 34 0.82 gi|22748711 hypothetical protein LOC122046 [Homo sapiens] 33 1.1 gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens] 33 1.4 gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens] 33 1.4 gi|238908495 similar to pleckstrin homology domain protein (5V32... 32 2.4 gi|154355004 strawberry notch homolog 2 isoform 2 [Homo sapiens] 32 3.1 gi|154355002 strawberry notch homolog 2 isoform 1 [Homo sapiens] 32 3.1 gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens] 32 3.1 gi|73747844 ligase III, DNA, ATP-dependent isoform beta precurso... 31 5.3 gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precurs... 31 5.3 gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 30 9.0 gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 30 9.0 gi|21735548 centrosomal protein 2 [Homo sapiens] 30 9.0 gi|31742501 sorting nexin family member 27 [Homo sapiens] 30 9.0 >gi|194272176 phospholipase D1 isoform b [Homo sapiens] Length = 1036 Score = 2111 bits (5469), Expect = 0.0 Identities = 1036/1036 (100%), Positives = 1036/1036 (100%) Query: 1 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA 60 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA Sbjct: 1 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA 60 Query: 61 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF 120 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF Sbjct: 61 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF 120 Query: 121 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR 180 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR Sbjct: 121 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR 180 Query: 181 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC 240 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC Sbjct: 181 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC 240 Query: 241 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID 300 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID Sbjct: 241 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID 300 Query: 301 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG 360 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG Sbjct: 301 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG 360 Query: 361 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY 420 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY Sbjct: 361 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY 420 Query: 421 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI 480 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI Sbjct: 421 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI 480 Query: 481 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS 540 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS Sbjct: 481 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS 540 Query: 541 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH 600 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH Sbjct: 541 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH 600 Query: 601 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI 660 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI Sbjct: 601 GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI 660 Query: 661 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH 720 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH Sbjct: 661 QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH 720 Query: 721 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY 780 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY Sbjct: 721 EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY 780 Query: 781 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL 840 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL Sbjct: 781 VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL 840 Query: 841 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP 900 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP Sbjct: 841 RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP 900 Query: 901 SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY 960 SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY Sbjct: 901 SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY 960 Query: 961 DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL 1020 DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL Sbjct: 961 DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL 1020 Query: 1021 PSVGTKEAIVPMEVWT 1036 PSVGTKEAIVPMEVWT Sbjct: 1021 PSVGTKEAIVPMEVWT 1036 >gi|4505873 phospholipase D1 isoform a [Homo sapiens] Length = 1074 Score = 2090 bits (5415), Expect = 0.0 Identities = 1035/1074 (96%), Positives = 1036/1074 (96%), Gaps = 38/1074 (3%) Query: 1 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA 60 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA Sbjct: 1 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA 60 Query: 61 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF 120 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF Sbjct: 61 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF 120 Query: 121 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR 180 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR Sbjct: 121 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR 180 Query: 181 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC 240 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC Sbjct: 181 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC 240 Query: 241 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID 300 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID Sbjct: 241 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID 300 Query: 301 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG 360 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG Sbjct: 301 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG 360 Query: 361 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY 420 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY Sbjct: 361 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY 420 Query: 421 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI 480 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI Sbjct: 421 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI 480 Query: 481 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS 540 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS Sbjct: 481 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS 540 Query: 541 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTS---------------- 584 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTS Sbjct: 541 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL 600 Query: 585 ----------------------NTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL 622 +TGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL Sbjct: 601 KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL 660 Query: 623 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL 682 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL Sbjct: 661 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL 720 Query: 683 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE 742 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE Sbjct: 721 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE 780 Query: 743 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ 802 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ Sbjct: 781 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ 840 Query: 803 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL 862 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL Sbjct: 841 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL 900 Query: 863 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF 922 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF Sbjct: 901 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF 960 Query: 923 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI 982 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI Sbjct: 961 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI 1020 Query: 983 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT 1036 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT Sbjct: 1021 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT 1074 >gi|156564407 phospholipase D2 [Homo sapiens] Length = 933 Score = 546 bits (1407), Expect = e-155 Identities = 265/459 (57%), Positives = 337/459 (73%), Gaps = 3/459 (0%) Query: 578 SSIDSTSNTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPR 637 SS + S + R +L FW GKDY N + KDWVQLD+PF DFIDR +TPR Sbjct: 478 SSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPR 537 Query: 638 MPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVP 697 MPW D+ VHG ARD+ARHFIQRWNFTK K+KY++ +YP+LLPKS +TA++L + +P Sbjct: 538 MPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLP 597 Query: 698 GSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFN 757 G VQ+LRS WSAG E SI AY+H I S+H++YIENQFFISC+D + V N Sbjct: 598 GGQCTTVQVLRSVDRWSAGTL--ENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLN 655 Query: 758 KIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGEN 817 K+GD I RILKAH++ YRVYV++PLLPGFEGDISTGGGN++QAI+HF YRT+CRGE Sbjct: 656 KVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEY 715 Query: 818 SILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANIN 877 SIL +LKA +G W +YIS CGLRTH EL G+ V+ELIY+HSK+LIADD TVIIGSANIN Sbjct: 716 SILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANIN 775 Query: 878 DRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQ 937 DRS+LGKRDSE+AV+++DTET PS+M+G EYQAGRFA LR CF V+LG P D++ Sbjct: 776 DRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLR 835 Query: 938 DPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEE 997 DP+ D FF ++W A NA IY+++FRCLP++ +L LR+++ LA P A Sbjct: 836 DPICDDFF-QLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARS 894 Query: 998 ELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT 1036 EL +++G LV FP FL +ESLLP +G+KE ++P+EVWT Sbjct: 895 ELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT 933 Score = 528 bits (1359), Expect = e-149 Identities = 268/491 (54%), Positives = 344/491 (70%), Gaps = 18/491 (3%) Query: 26 ENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQV 85 + LD+ +L E +EVD DP + PF AIY Q K + + G P+ AQV Sbjct: 13 DELDSSQLQMESDEVDTLKEGEDPA--DRMHPFLAIYELQSLKVHPL-VFAPGVPVTAQV 69 Query: 86 LEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRR 145 + ER+TS ++V + LY++ LTHG+F W K+K++HFQE HR+LL++K + + +P R Sbjct: 70 VGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSL-LPLAR 128 Query: 146 HTFRRQNVREEP-REMPSLPRSS-ENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATT 203 R+ REMPSLPR+ E R ++K LE+YL ++L M YRNYHA T Sbjct: 129 FAVAYSPARDAGNREMPSLPRAGPEGSTRHAA--SKQKYLENYLNRLLTMSFYRNYHAMT 186 Query: 204 EFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLL 263 EFL++SQLSFI DLG KG+EGMI KRSGGHR+PGL CCG+ + CYRWSKRWL+VKDSFLL Sbjct: 187 EFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLL 246 Query: 264 YMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAI 323 YM ++GAI+FV L D F+++VGK+ TE ++G+RID R+LILKC+SYR ARWW I Sbjct: 247 YMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEI 306 Query: 324 EEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWL 383 E Q G +FL+ HR SYA + LA+W+VN GYF VA+A+ A EEIFITDWWL Sbjct: 307 TELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWL 366 Query: 384 SPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHP 443 SPE++LKRP + WRLD +LKRKA++GVR+ I+L+KEVELALGINS Y+KR LM LHP Sbjct: 367 SPEVYLKRP-AHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHP 425 Query: 444 NIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRV 503 NIKVMRHPD V+ LWAHHEKL+++DQ VAF+GG+DLAYGRWDD +RLTD+G Sbjct: 426 NIKVMRHPDQVT----LWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGD---- 477 Query: 504 TSGPSLGSLPP 514 S S S PP Sbjct: 478 -SSESAASQPP 487 >gi|7661880 centaurin beta1 [Homo sapiens] Length = 740 Score = 34.7 bits (78), Expect = 0.48 Identities = 24/112 (21%), Positives = 53/112 (47%), Gaps = 1/112 (0%) Query: 216 DLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFV 275 +LG + E + + GG + G A WS+RW ++ + L+Y K + V Sbjct: 249 ELGGEEPEPSLREGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKKYKDPVTVV 308 Query: 276 LLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEEFI 327 + + +K+ ++E ++ + + S++ +L+ +S R + W A++ I Sbjct: 309 VDDLRLCTVKL-CPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSI 359 >gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5 [Homo sapiens] Length = 6907 Score = 33.9 bits (76), Expect = 0.82 Identities = 38/183 (20%), Positives = 76/183 (41%), Gaps = 9/183 (4%) Query: 581 DSTSNTGSIRSLQTGVGELHGETRFWHG--KDYCNFVFKDWVQLDKPFADFIDRYSTPRM 638 ++ S+ GS LQ +G+L G ++ C K W Q+++ AD + + + Sbjct: 5326 EAESSEGSWEKLQEVIGKLKGLCPSVAEIIEEKCQNTHKRWTQVNQAIADQLQKAQSLLQ 5385 Query: 639 PWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPG 698 W ++A HG+AA AR Q F ++ + +LP + EL++ V Sbjct: 5386 LWKAYSNA-HGEAA---ARLKQQEAKFQQLANISMSGNNLAEILPPALQDIKELQHDVQK 5441 Query: 699 SVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNK 758 + A L++++ + E S H + + + Y+E + + + V ++ Sbjct: 5442 TKEA---FLQNSSVLDRLPQPAESSTHMLLPGPLHSLQRAAYLEKMLLVKANEFEFVLSQ 5498 Query: 759 IGD 761 D Sbjct: 5499 FKD 5501 >gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1 [Homo sapiens] Length = 6885 Score = 33.9 bits (76), Expect = 0.82 Identities = 38/183 (20%), Positives = 76/183 (41%), Gaps = 9/183 (4%) Query: 581 DSTSNTGSIRSLQTGVGELHGETRFWHG--KDYCNFVFKDWVQLDKPFADFIDRYSTPRM 638 ++ S+ GS LQ +G+L G ++ C K W Q+++ AD + + + Sbjct: 5326 EAESSEGSWEKLQEVIGKLKGLCPSVAEIIEEKCQNTHKRWTQVNQAIADQLQKAQSLLQ 5385 Query: 639 PWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPG 698 W ++A HG+AA AR Q F ++ + +LP + EL++ V Sbjct: 5386 LWKAYSNA-HGEAA---ARLKQQEAKFQQLANISMSGNNLAEILPPALQDIKELQHDVQK 5441 Query: 699 SVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNK 758 + A L++++ + E S H + + + Y+E + + + V ++ Sbjct: 5442 TKEA---FLQNSSVLDRLPQPAESSTHMLLPGPLHSLQRAAYLEKMLLVKANEFEFVLSQ 5498 Query: 759 IGD 761 D Sbjct: 5499 FKD 5501 >gi|109150427 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1 isoform a [Homo sapiens] Length = 370 Score = 33.9 bits (76), Expect = 0.82 Identities = 51/214 (23%), Positives = 85/214 (39%), Gaps = 37/214 (17%) Query: 563 YKQLHRHHLHDADSISSIDSTSNT--------------GSIRSLQTGVGELHGETRFWHG 608 Y+QL R HL DS++ + T G SL V +H ET G Sbjct: 14 YQQLLREHLWIGDSVAGALDPAQTSLLTNLHCFQPDVSGFSVSLAGTVACIHWETSQLSG 73 Query: 609 -KDYCNFVF---KDWVQLDKPFA------DFIDRYSTPRMPWHDIASAVHGKAARDVARH 658 ++ V +D +Q +K +FI+R S + ++ S V + +A H Sbjct: 74 LPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQMADH 133 Query: 659 FIQRWNFTKIMKS--KYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAG 716 T++MK +Y + YP L P Q H + G+ +V S + Sbjct: 134 -------TEVMKGIHQYPGVRYPVLTPNLQGFHHAV---AAGATEISVFGAASESFSKKN 183 Query: 717 IKYHEESIHAAYVHVIENSRHYIYIENQFFISCA 750 I E + V++++RH + I + ++SCA Sbjct: 184 INCSIEESMGKFEEVVKSARH-MNIPARGYVSCA 216 >gi|22748711 hypothetical protein LOC122046 [Homo sapiens] Length = 289 Score = 33.5 bits (75), Expect = 1.1 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 6/69 (8%) Query: 638 MPWH------DIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHE 691 +PW ++ A+ + R F+ R KI KS + SL + LLP+ T Sbjct: 124 LPWKIPASMKEVNKALSNQFISLTKRDFVDRSKAQKIKKSSHLSLEWKKLLPQPPDTEFR 183 Query: 692 LRYQVPGSV 700 YQ+P + Sbjct: 184 RNYQIPAKI 192 >gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens] Length = 1127 Score = 33.1 bits (74), Expect = 1.4 Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 21/127 (16%) Query: 79 CPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIR 138 CP + + L VE ++ +LY +L G K V +KH ++ +LL F Sbjct: 262 CPERNESLSVE-----DQMEQSSLYFWDLLEGSEKAVVGTTYKHLKDLLSKLLNSGYFES 316 Query: 139 IPIP---------------TRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQL 183 IP+P + + + E +E SL ++ I+ ++FL RR Sbjct: 317 IPVPKNAKEKEVPLEEEMLIQSEKKTQLSKTESVKESESLMEFAQPEIQPQEFLNRRYMT 376 Query: 184 E-DYLTK 189 E DY K Sbjct: 377 EVDYSNK 383 >gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens] Length = 1077 Score = 33.1 bits (74), Expect = 1.4 Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 21/127 (16%) Query: 79 CPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIR 138 CP + + L VE ++ +LY +L G K V +KH ++ +LL F Sbjct: 262 CPERNESLSVE-----DQMEQSSLYFWDLLEGSEKAVVGTTYKHLKDLLSKLLNSGYFES 316 Query: 139 IPIP---------------TRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQL 183 IP+P + + + E +E SL ++ I+ ++FL RR Sbjct: 317 IPVPKNAKEKEVPLEEEMLIQSEKKTQLSKTESVKESESLMEFAQPEIQPQEFLNRRYMT 376 Query: 184 E-DYLTK 189 E DY K Sbjct: 377 EVDYSNK 383 >gi|238908495 similar to pleckstrin homology domain protein (5V327) [Homo sapiens] Length = 506 Score = 32.3 bits (72), Expect = 2.4 Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 39/222 (17%) Query: 244 GRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIK------------VGKKET 291 GR +WS+R+ I+K+SFLLY +S +F +K F I K+E Sbjct: 41 GRPSAKWSRRFFIIKESFLLYYS-ESEKKSFE--TNKYFNIHPKGVIPLGGCLVEPKEEP 97 Query: 292 ETKYGIRI---DNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQE 348 Y ++I D L+ + + +W E +Q+ G K+ + G A+ + Sbjct: 98 SMPYAMKISHQDFHGNILLAAESEFEQTQWL-----EMLQESGKVTWKNAQLGE--AMIK 150 Query: 349 NALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRK 408 + A+ AK E + MEE + E+ L+R E RL+ +L+ + Sbjct: 151 SLEAQGLQLAKEKQEYLDKLMEE------------TEELCLQREQRE-ELERLNQVLEAE 197 Query: 409 AQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRH 450 QQ + L E E + E T R L + K +RH Sbjct: 198 KQQFEEVVQELRMEQE-QIKRELELTARCLKGVEQEKKELRH 238 >gi|154355004 strawberry notch homolog 2 isoform 2 [Homo sapiens] Length = 1309 Score = 32.0 bits (71), Expect = 3.1 Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 27/192 (14%) Query: 863 IADDNTVIIGSANIND---RSMLGKRDSEMAVIVQDTETV---------PSVMDGKEYQA 910 +A D V+IG + + R +LG+ D + V E V PS ++ A Sbjct: 507 LARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRKRDRGA 566 Query: 911 G---------RFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYD 961 G R A+ RL C + + D S DP D F S + I D Sbjct: 567 GSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVD 626 Query: 962 KVFRCLPNDEVHNLIQL-RDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL 1020 V LP+D+ L L RD VL + + ++ ++ L K+R + P L E L+ Sbjct: 627 AV--GLPSDDRGPLCLLQRDPHGPGVLERVERLK-QDLLDKVRRLGRELPVNTLDE--LI 681 Query: 1021 PSVGTKEAIVPM 1032 +G + + M Sbjct: 682 DQLGGPQRVAEM 693 >gi|154355002 strawberry notch homolog 2 isoform 1 [Homo sapiens] Length = 1366 Score = 32.0 bits (71), Expect = 3.1 Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 27/192 (14%) Query: 863 IADDNTVIIGSANIND---RSMLGKRDSEMAVIVQDTETV---------PSVMDGKEYQA 910 +A D V+IG + + R +LG+ D + V E V PS ++ A Sbjct: 564 LARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRKRDRGA 623 Query: 911 G---------RFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYD 961 G R A+ RL C + + D S DP D F S + I D Sbjct: 624 GSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVD 683 Query: 962 KVFRCLPNDEVHNLIQL-RDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL 1020 V LP+D+ L L RD VL + + ++ ++ L K+R + P L E L+ Sbjct: 684 AV--GLPSDDRGPLCLLQRDPHGPGVLERVERLK-QDLLDKVRRLGRELPVNTLDE--LI 738 Query: 1021 PSVGTKEAIVPM 1032 +G + + M Sbjct: 739 DQLGGPQRVAEM 750 >gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens] Length = 1079 Score = 32.0 bits (71), Expect = 3.1 Identities = 27/128 (21%), Positives = 59/128 (46%), Gaps = 7/128 (5%) Query: 87 EVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELL---KYKAFI--RIPI 141 E+E T + ++ Y+++ E + +V+ +++H++L KY A I + + Sbjct: 118 EIEGLKETLKALQVSKYSLQKKVSEMEQKVQLHLLAKEDYHKQLSEIEKYYATITGQFGL 177 Query: 142 PTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHA 201 H QNVRE + L S+ N +E + +K+L+ + ++K + Y Sbjct: 178 VKENHEKLEQNVREAIQSNKRL--SALNKKQEAEICSLKKELKKAASDLIKSKVTCQYKM 235 Query: 202 TTEFLDIS 209 E ++++ Sbjct: 236 GEENINLT 243 >gi|73747844 ligase III, DNA, ATP-dependent isoform beta precursor [Homo sapiens] Length = 949 Score = 31.2 bits (69), Expect = 5.3 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 15/84 (17%) Query: 179 RRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGL 238 RRK L D + +I M+ T+ LD++ + I + +G+EG+++K G PG Sbjct: 613 RRKFLHDNMVEIPNRIMFSEMKRVTKALDLADM--ITRVIQEGLEGLVLKDVKGTYEPG- 669 Query: 239 NCCGQGRACYRWSKRWLIVKDSFL 262 + WL VK +L Sbjct: 670 ------------KRHWLKVKKDYL 681 >gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precursor [Homo sapiens] Length = 1009 Score = 31.2 bits (69), Expect = 5.3 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 15/84 (17%) Query: 179 RRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGL 238 RRK L D + +I M+ T+ LD++ + I + +G+EG+++K G PG Sbjct: 613 RRKFLHDNMVEIPNRIMFSEMKRVTKALDLADM--ITRVIQEGLEGLVLKDVKGTYEPG- 669 Query: 239 NCCGQGRACYRWSKRWLIVKDSFL 262 + WL VK +L Sbjct: 670 ------------KRHWLKVKKDYL 681 >gi|24797143 sorting nexin 14 isoform b [Homo sapiens] Length = 893 Score = 30.4 bits (67), Expect = 9.0 Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 10/68 (14%) Query: 179 RRKQLEDYLTKILKMPMYRNYHATTEFLDIS--QLSFIHDLGP--------KGIEGMIMK 228 +R++ ++YL K+L+ P N +FL + + F+ + P K + G +MK Sbjct: 603 KREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMK 662 Query: 229 RSGGHRIP 236 G H P Sbjct: 663 EKGQHLEP 670 >gi|24797145 sorting nexin 14 isoform a [Homo sapiens] Length = 946 Score = 30.4 bits (67), Expect = 9.0 Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 10/68 (14%) Query: 179 RRKQLEDYLTKILKMPMYRNYHATTEFLDIS--QLSFIHDLGP--------KGIEGMIMK 228 +R++ ++YL K+L+ P N +FL + + F+ + P K + G +MK Sbjct: 656 KREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMK 715 Query: 229 RSGGHRIP 236 G H P Sbjct: 716 EKGQHLEP 723 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 30.4 bits (67), Expect = 9.0 Identities = 16/42 (38%), Positives = 23/42 (54%) Query: 144 RRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLED 185 R R Q RE+ E R ENMI+E+Q LG+ ++ E+ Sbjct: 2047 RDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEE 2088 >gi|31742501 sorting nexin family member 27 [Homo sapiens] Length = 528 Score = 30.4 bits (67), Expect = 9.0 Identities = 23/101 (22%), Positives = 42/101 (41%), Gaps = 6/101 (5%) Query: 119 KFKHFQEFHRELLKYKAFIR----IPIPTRRHTFRRQNVREEPREM--PSLPRSSENMIR 172 ++KH ++ + + Y ++ R QN++ E P LP + Sbjct: 169 RYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLS 228 Query: 173 EEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSF 213 E+Q RR+ LE+YL K+ + + EFL S ++ Sbjct: 229 EQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENY 269 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,377,211 Number of Sequences: 37866 Number of extensions: 1701222 Number of successful extensions: 3788 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 6 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 3763 Number of HSP's gapped (non-prelim): 28 length of query: 1036 length of database: 18,247,518 effective HSP length: 112 effective length of query: 924 effective length of database: 14,006,526 effective search space: 12942030024 effective search space used: 12942030024 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.