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Search of human proteins with 194248095
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194248095 epsin 1 isoform b [Homo sapiens]
(576 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194248095 epsin 1 isoform b [Homo sapiens] 1189 0.0
gi|41350201 epsin 1 isoform c [Homo sapiens] 1117 0.0
gi|194272148 epsin 1 isoform a [Homo sapiens] 1116 0.0
gi|156671217 epsin 2 isoform a [Homo sapiens] 461 e-129
gi|156671215 epsin 2 isoform b [Homo sapiens] 460 e-129
gi|157388929 epsin 3 [Homo sapiens] 446 e-125
gi|31377575 ENTH domain containing 1 [Homo sapiens] 211 1e-54
gi|156671219 epsin 2 isoform c [Homo sapiens] 185 9e-47
gi|7661968 epsin 4 [Homo sapiens] 174 2e-43
gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 1e-18
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 79 1e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens] 74 3e-13
gi|210032580 SET domain containing 1B [Homo sapiens] 73 6e-13
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 73 6e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 72 1e-12
gi|116284392 mucin 2 precursor [Homo sapiens] 72 2e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 2e-12
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 71 2e-12
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 70 4e-12
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 69 9e-12
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 69 9e-12
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 69 2e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 67 3e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 67 3e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 67 3e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 67 3e-11
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 67 3e-11
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 67 4e-11
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 67 6e-11
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 67 6e-11
>gi|194248095 epsin 1 isoform b [Homo sapiens]
Length = 576
Score = 1189 bits (3075), Expect = 0.0
Identities = 576/576 (100%), Positives = 576/576 (100%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
Sbjct: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
Sbjct: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
Query: 181 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM 240
SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM
Sbjct: 181 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM 240
Query: 241 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 300
AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
Sbjct: 241 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 300
Query: 301 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 360
VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
Sbjct: 301 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 360
Query: 361 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 420
SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS
Sbjct: 361 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 420
Query: 421 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 480
AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
Sbjct: 421 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 480
Query: 481 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 540
LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
Sbjct: 481 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 540
Query: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 576
VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
Sbjct: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 576
>gi|41350201 epsin 1 isoform c [Homo sapiens]
Length = 550
Score = 1117 bits (2890), Expect = 0.0
Identities = 550/576 (95%), Positives = 550/576 (95%), Gaps = 26/576 (4%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
Sbjct: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
Sbjct: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
Query: 181 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM 240
SGEEELQLQLALAMSKEEADQ EERIRRGDDLRLQM
Sbjct: 181 SGEEELQLQLALAMSKEEADQ-------------------------EERIRRGDDLRLQM 215
Query: 241 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 300
AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
Sbjct: 216 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 275
Query: 301 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 360
VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
Sbjct: 276 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 335
Query: 361 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 420
SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTT AGGFDTEPDEFSDFDRLRTALPTSGSS
Sbjct: 336 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTT-AGGFDTEPDEFSDFDRLRTALPTSGSS 394
Query: 421 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 480
AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
Sbjct: 395 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 454
Query: 481 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 540
LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
Sbjct: 455 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 514
Query: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 576
VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
Sbjct: 515 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 550
>gi|194272148 epsin 1 isoform a [Homo sapiens]
Length = 662
Score = 1116 bits (2887), Expect = 0.0
Identities = 546/576 (94%), Positives = 550/576 (95%), Gaps = 25/576 (4%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
Sbjct: 112 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 171
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
Sbjct: 172 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 231
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 180
VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
Sbjct: 232 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS 291
Query: 181 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM 240
SGEEELQL QLAL++S+EE D+EERIRRGDDLRLQM
Sbjct: 292 SGEEELQL-------------------------QLALAMSKEEADQEERIRRGDDLRLQM 326
Query: 241 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 300
AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
Sbjct: 327 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 386
Query: 301 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 360
VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
Sbjct: 387 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV 446
Query: 361 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 420
SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS
Sbjct: 447 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 506
Query: 421 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 480
AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
Sbjct: 507 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 566
Query: 481 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 540
LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
Sbjct: 567 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 626
Query: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 576
VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
Sbjct: 627 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 662
>gi|156671217 epsin 2 isoform a [Homo sapiens]
Length = 584
Score = 461 bits (1185), Expect = e-129
Identities = 295/657 (44%), Positives = 360/657 (54%), Gaps = 154/657 (23%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
M+TSS+RRQMKNIV+NYSEAEIKVREATSNDPWGPSSSLM+EIADLTYNVVAFSEIMSM+
Sbjct: 1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKA+TL++YLIKTGSERV+QQC+EN++A+QTLKDFQY+DRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA-----AVGSGPP----- 170
+NVREK+KQLVALL+DE+RL+ ERA ALKTKE++AQ AT + GS P
Sbjct: 121 INVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTS 180
Query: 171 -------------------------PEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSC 205
E EQA PQ+SGEEELQLQLALAMS+E A+Q
Sbjct: 181 HSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERL 240
Query: 206 GPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT 265
DD +LQ+AL SR + K I + K ++++L+DL D
Sbjct: 241 RRGDDLRLQMALEESRRDTVK---------------IPKKKEHGSLPQQTTLLDLMDALP 285
Query: 266 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW---- 321
+ P AA ++PWG +PWGGPA ++ DPW
Sbjct: 286 SSGP-------------------AAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFG 326
Query: 322 -RPAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPW 379
+PAA S+DPWG T A DPW +S +G ASD W
Sbjct: 327 TKPAA----SIDPWGVPTGATVQSVPKNSDPWAASQQPASSAGKRASDAW---------- 372
Query: 380 GGSPAKPSTNGTTAAGGFD-------TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVP 432
A +T + +G F+ T D+FS+FD LRT+ T+ S +P
Sbjct: 373 ---GAVSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAES--------VTSLP 421
Query: 433 ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPG 492
+++ G S P +A RKTPESFLGPNAALV+LDSLV+RP
Sbjct: 422 SQNNGTTSPDPFESQPLTVASSKPSSA--------RKTPESFLGPNAALVNLDSLVTRPA 473
Query: 493 PTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV-------------- 538
P A++ NPFL G PAT V NPFQ P LTLNQLR SPV
Sbjct: 474 PP---AQSLNPFLAPGAPATSAPV-NPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVE 529
Query: 539 ------------PPVPGAPPTYISPLG-------GGPGLPPMMPPGPPAPNTNPFLL 576
P GA + ++PLG G G+PP TNPFLL
Sbjct: 530 SMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGSVGIPP--SAAQATGTTNPFLL 584
>gi|156671215 epsin 2 isoform b [Homo sapiens]
Length = 641
Score = 460 bits (1183), Expect = e-129
Identities = 303/693 (43%), Positives = 373/693 (53%), Gaps = 169/693 (24%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
M+TSS+RRQMKNIV+NYSEAEIKVREATSNDPWGPSSSLM+EIADLTYNVVAFSEIMSM+
Sbjct: 1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
WKRLNDHGKNWRHVYKA+TL++YLIKTGSERV+QQC+EN++A+QTLKDFQY+DRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA-----AVGSGPP----P 171
+NVREK+KQLVALL+DE+RL+ ERA ALKTKE++AQ AT + GS P
Sbjct: 121 INVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTS 180
Query: 172 EAEQAWPQSSG-------------------------EEELQ---------LQLALA---- 193
+EQ + ++ G EELQ L LA
Sbjct: 181 HSEQEYGKAGGSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLASRPN 240
Query: 194 --------------------MSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRG 233
+S E P E++ QLQLAL++SRE ++EER+RRG
Sbjct: 241 GDWSQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRG 300
Query: 234 DDLRLQMAIEESKRET----GGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTA 289
DDLRLQMA+EES+R+T KE SL + P++ P A
Sbjct: 301 DDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGP-------------A 347
Query: 290 APTSDPWGGPPVPPAADPWGGPAPTPASGDPW-----RPAAPAGPSVDPWG-GTPAPAAG 343
A ++PWG +PWGGPA ++ DPW +PAA S+DPWG T A
Sbjct: 348 AQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAA----SIDPWGVPTGATVQS 403
Query: 344 EGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFD----- 398
DPW +S +G ASD W A +T + +G F+
Sbjct: 404 VPKNSDPWAASQQPASSAGKRASDAW-------------GAVSTTKPVSVSGSFELFSNL 450
Query: 399 --TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPP 456
T D+FS+FD LRT+ T+ S +P+++ G S P
Sbjct: 451 NGTIKDDFSEFDNLRTSKKTAES--------VTSLPSQNNGTTSPDPFESQPLTVASSKP 502
Query: 457 PAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSV 516
+A RKTPESFLGPNAALV+LDSLV+RP P A++ NPFL G PAT V
Sbjct: 503 SSA--------RKTPESFLGPNAALVNLDSLVTRPAPP---AQSLNPFLAPGAPATSAPV 551
Query: 517 TNPFQPAPPATLTLNQLRLSPV--------------------------PPVPGAPPTYIS 550
NPFQ P LTLNQLR SPV P GA + ++
Sbjct: 552 -NPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSSLT 610
Query: 551 PLG-------GGPGLPPMMPPGPPAPNTNPFLL 576
PLG G G+PP TNPFLL
Sbjct: 611 PLGPAMMNMVGSVGIPP--SAAQATGTTNPFLL 641
>gi|157388929 epsin 3 [Homo sapiens]
Length = 632
Score = 446 bits (1148), Expect = e-125
Identities = 300/672 (44%), Positives = 370/672 (55%), Gaps = 137/672 (20%)
Query: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
M+TS+LRRQ+KNIVHNYSEAEIKVREATSNDPWGP SSLMSEIADLT+N VAF+E+M M+
Sbjct: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
Query: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
W+RLND GKNWRHVYKA+TL++YL+KTGSERV+ QC+EN+Y +QTLKDFQY+DRDGKDQG
Sbjct: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLA-----------------------QT 157
VNVREK KQ++ALL+DE+RLR+ER HALKTKE++A
Sbjct: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR 180
Query: 158 ATASSAAVGSGPP---PEAEQAWPQSSGEEELQLQLALAMSKEEADQ--PPSCGPEDDAQ 212
+ SS S P + EQA PQ+SGEEELQLQLALAMS+EEA++ PP+ ++D Q
Sbjct: 181 GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ 240
Query: 213 LQLALSLSREEHDKEERIRRGDDLRL---------QMAIEESKRETGGKEE------SSL 257
LQLAL LSR+EH+KE R +GD + E +RE +EE SS+
Sbjct: 241 LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI 300
Query: 258 MDLADVFTAPAPAPTT----DPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 313
+DLAD+F P+T DPW P P + WG P+ADPW P P
Sbjct: 301 LDLADIFVPALAPPSTHCSADPWDIP----GFRPNTEASGSSWG-----PSADPW-SPIP 350
Query: 314 TP---ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWT 370
+ + PW P S +PWG TP AG PT DPW ++ P P T
Sbjct: 351 SGTVLSRSQPW-DLTPMLSSSEPWGRTPVLPAGP-PTTDPWA-------LNSPHHKLPST 401
Query: 371 PAPAFSDPWGGSPAKPST-NGTTAAGGFDTEPDEFSDFDRLRTALPT-SGSSAGELELLA 428
A DPWG S T G + F P+ + L ALP+ SS EL+L
Sbjct: 402 GA----DPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFG 457
Query: 429 GEVPA------RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNA-AL 481
P+ + P A D+ G L EA+ P A +TPESFLGP+A +L
Sbjct: 458 DPSPSSKQNGTKEPDALDL----GILGEALTQPSKEARAC------RTPESFLGPSASSL 507
Query: 482 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL-SPVPP 540
V+LDSLV P AK NPFL G + PS TNPF P TLNQ+R SP
Sbjct: 508 VNLDSLVK----APQVAKTRNPFLTG---LSAPSPTNPFGAGEPGRPTLNQMRTGSPALG 560
Query: 541 VPGAP--------------PTYISPLGGGPGLP---------------PMMP-------- 563
+ G P P +S + G LP P++P
Sbjct: 561 LAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPR 620
Query: 564 PGPPAPNTNPFL 575
P PP TNPFL
Sbjct: 621 PPPPQTGTNPFL 632
>gi|31377575 ENTH domain containing 1 [Homo sapiens]
Length = 607
Score = 211 bits (538), Expect = 1e-54
Identities = 98/163 (60%), Positives = 129/163 (79%)
Query: 5 SLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL 64
+ RRQ+KN V NYS+AEIKVREATSNDPWGPSSSLM +I+DLT+N ++ SEIM+M+W RL
Sbjct: 2 AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
Query: 65 NDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVR 124
NDHGKNWRHVYK++TLM+YLIK GS++V Q C+E +QTLKDFQ++D GKDQG +R
Sbjct: 62 NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
Query: 125 EKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGS 167
EK+KQ++ LL DE L +ER A +T+++ + + S +GS
Sbjct: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGS 164
>gi|156671219 epsin 2 isoform c [Homo sapiens]
Length = 356
Score = 185 bits (470), Expect = 9e-47
Identities = 145/408 (35%), Positives = 185/408 (45%), Gaps = 102/408 (25%)
Query: 219 LSREEHDKEERIRRGDDLRLQMAIEESKRET----GGKEESSLMDLADVFTAPAPAPTTD 274
+SRE ++EER+RRGDDLRLQMA+EES+R+T KE SL + P++
Sbjct: 1 MSREVAEQEERLRRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSG 60
Query: 275 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW-----RPAAPAGP 329
P AA ++PWG +PWGGPA ++ DPW +PAA
Sbjct: 61 P-------------AAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAA---- 103
Query: 330 SVDPWG-GTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPST 388
S+DPWG T A DPW +S +G ASD W A +T
Sbjct: 104 SIDPWGVPTGATVQSVPKNSDPWAASQQPASSAGKRASDAWG-------------AVSTT 150
Query: 389 NGTTAAGGFD-------TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDM 441
+ +G F+ T D+FS+FD LRT+ T+ S +P+++ G
Sbjct: 151 KPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAESVTS--------LPSQNNGTTSP 202
Query: 442 SGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKAS 501
S P +A RKTPESFLGPNAALV+LDSLV+RP P A++
Sbjct: 203 DPFESQPLTVASSKPSSA--------RKTPESFLGPNAALVNLDSLVTRPAPP---AQSL 251
Query: 502 NPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV----------------------- 538
NPFL G PAT V NPFQ P LTLNQLR SPV
Sbjct: 252 NPFLAPGAPATSAPV-NPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTS 310
Query: 539 ---PPVPGAPPTYISPLG-------GGPGLPPMMPPGPPAPNTNPFLL 576
P GA + ++PLG G G+PP TNPFLL
Sbjct: 311 AAPQPALGATGSSLTPLGPAMMNMVGSVGIPP--SAAQATGTTNPFLL 356
>gi|7661968 epsin 4 [Homo sapiens]
Length = 625
Score = 174 bits (442), Expect = 2e-43
Identities = 173/574 (30%), Positives = 254/574 (44%), Gaps = 57/574 (9%)
Query: 12 NIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKR-LNDHGKN 70
N+V NYSE E KVREAT++DPWGPS LM EIA T+ F E+M+M+W R L D+ KN
Sbjct: 16 NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
Query: 71 WRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQL 130
WR VYK++ L+ YLI+ GSERV +E++Y +++L+++ +VD GKDQG+N+R+K K+L
Sbjct: 76 WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
Query: 131 VALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEEL-QLQ 189
V +D+DRLREER A K K+K SS +VG E P+S +EE + +
Sbjct: 136 VEFAQDDDRLREERKKAKKNKDKY---VGVSSDSVGGFRYSERYDPEPKSKWDEEWDKNK 192
Query: 190 LALAMSKEEADQPPSCGPEDDAQLQLALSLSRE-------EHDKEERIRRGDDLRLQMAI 242
A S + + G D + RE + D+E++ RRG + +
Sbjct: 193 SAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKARRGRSPKGEFKD 252
Query: 243 EESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVP 302
EE ET + + + T T +P AAA T S
Sbjct: 253 EE---ETVTTKHIHITQATET-TTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHT 308
Query: 303 PAADPWGGPAPTPASGDPW----RPAAPAGPSVDPWGGTP--APAAGEGPTPDPWGSSDG 356
P + + +SGD + G S D +GG AA G P ++ G
Sbjct: 309 PQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSG 368
Query: 357 GVPVSGPSASDPWTPAP-AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 415
SA + P A S + GS ++P+ E + P
Sbjct: 369 NGDFGDWSAFNQAPSGPVASSGEFFGSASQPAV--------------ELVSGSQSALGPP 414
Query: 416 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKT----- 470
+ S++ +L L G A + M+ S VG P + T +K+
Sbjct: 415 PAASNSSDLFDLMGSSQATMTSSQSMNFSMMS-TNTVGLGLPMSRSQNTDMVQKSVSKTL 473
Query: 471 PESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTL 530
P ++ P+ + LD+L+ PG + S P P T N QP T +
Sbjct: 474 PSTWSDPSVN-ISLDNLL-------PGMQPSKPQQPSLN--TMIQQQNMQQPMNVMTQSF 523
Query: 531 NQLRL-SPVPPVPGAPPTYISPLGGGPGLPPMMP 563
+ L SP +P P T + L GGP +P MP
Sbjct: 524 GAVNLSSPSNMLPVRPQT--NALIGGP-MPMSMP 554
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 92.0 bits (227), Expect = 1e-18
Identities = 107/365 (29%), Positives = 128/365 (35%), Gaps = 70/365 (19%)
Query: 265 TAPA---PAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP---------PVPPAA---DPWG 309
T PA P+P P P P A+ P AA P G P P PAA P G
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 310 GPAPTPASGDPWRPAAP-----AGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS 364
GPA G P PAA GP+ G P P A P+P GG+ + P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK------GGL-ATPPH 1122
Query: 365 ASDPWTPAPAFSDPWGG--------SPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT 416
P TPA P GG +P P+ + GG T P + + T
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 417 SGSSAGELELLAGEVPARSP----GAFDMSGVRGSLAEAVGSPPPA----ATPTP----T 464
G A A PA +P G +G+ +PP ATP+P T
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 465 PPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAK----------ASNPFL-----PGGG 509
P P GP A + P TPP K A NP + P GG
Sbjct: 1243 TPAATPPSPKGGP--ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 510 PATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAP-PTYISPLG--GGPGLPPMMPPGP 566
PAT P P PPA + PP GAP P ++P G P LP P
Sbjct: 1301 PATSPP---KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 567 PAPNT 571
P T
Sbjct: 1358 GGPTT 1362
Score = 92.0 bits (227), Expect = 1e-18
Identities = 112/366 (30%), Positives = 132/366 (36%), Gaps = 75/366 (20%)
Query: 267 PAPAPTT------DPWGGPAPMA---AAVPTAAPTSDPWGGP--------PVPPAADPWG 309
P APTT P GGPA + A P AA P GGP P+PPAA P
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-- 1110
Query: 310 GPAPTPASGDPWRPAAPAGPSVDP----WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA 365
P+P P AP P+ P G P G TP S G + P
Sbjct: 1111 -PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 366 SDPWTPAPAFSDPWG--------GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTS 417
P TPA P G G+P P+ + GG T + + T
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Query: 418 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTP---TPPTRK----T 470
G A A PA +P +G A +PPP PTP TPP+ K T
Sbjct: 1230 GGLATPSPKGAPTTPAATP-----PSPKGGPA----TPPPKGAPTPPAATPPSLKGGLAT 1280
Query: 471 PESFLGPNAALVDLDSLVSRPGPTPP-GA---KASNPFLPGGGPATGPSVTNPFQPA--- 523
P PN A+V S P +PP GA A+ P P G P T P P PA
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 524 --PPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP--------GLPPMMPPGP------P 567
P T TL + P G P T S G P G P M PP P P
Sbjct: 1341 PSPKGTPTLP----ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396
Query: 568 APNTNP 573
+P +P
Sbjct: 1397 SPKGDP 1402
Score = 90.1 bits (222), Expect = 5e-18
Identities = 105/371 (28%), Positives = 135/371 (36%), Gaps = 85/371 (22%)
Query: 265 TAPAPAPTTDPWGG---PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS---- 317
T PA P + P GG P P A AA P GG PP PA TP S
Sbjct: 1127 TTPAATPPS-PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 318 ----GDPWRPAAPAGPSVDPWGGTPAPAAGEGPT------PDPWGS----SDGGVPVSGP 363
P PA P GG P+ PT P P G S G P + P
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT-P 1244
Query: 364 SASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGE 423
+A+ P + P G+P P+ + GG T P + + + T G A
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
Query: 424 LELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTP---TPPTRK--------TPE 472
A PA +P + +GS G+PPP PTP TPP+ K TP
Sbjct: 1305 PPKGAPTPPAATPPS-----PKGS----PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 473 SFLGPNAALVDLDSLVSRPGPTPPGAKASN---PFLPGGGPATGPSVTNPF-QPAPPATL 528
S GP S+ GPTPP A S+ P + P GP++ +P P PA +
Sbjct: 1356 SKGGPTTPS-------SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 529 TLNQLRLSPVPPV---------------PGAPPTYI-------SPLGG--------GPGL 558
L+ + +P PV P P + +P GG P L
Sbjct: 1409 PLSPKK-APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 559 PPMMPPGPPAP 569
P + PP P P
Sbjct: 1468 PAVTPPSPKEP 1478
Score = 77.8 bits (190), Expect = 3e-14
Identities = 101/334 (30%), Positives = 117/334 (35%), Gaps = 51/334 (15%)
Query: 266 APAPAPTTDPWGGPAPMAAAVPT--AAPTSDPWGGPPVPPAA---DPWGGPA-PTPASGD 319
AP AP A A P P S G P PPAA P GGPA P+P
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP---- 959
Query: 320 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP-WTPAPAFSDP 378
W P PA P GG P+ PTP ++ P GP+ P P P P
Sbjct: 960 KWAPTPPAATPPSPKGGPATPSPKGAPTPP---AATPPSPKGGPATPSPKGAPTPPAVTP 1016
Query: 379 WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
PS G+ AA F P S P +A L A PA +
Sbjct: 1017 -------PSPKGSPAATPF---PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT--- 1063
Query: 439 FDMSGVRGSLA--EAVGSP-PPAATPTPTP---PTRKTPESFLGPNAAL--VDLDSLVSR 490
+ +G A G+P PPAATP P+P P +P+ P AA L +
Sbjct: 1064 --LPSPKGGPATPSLKGAPTPPAATP-PSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 491 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP---VPPVPGAPPT 547
P P A+ P P GG AT P P PA L P P P A P
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
Query: 548 YISPLG--------GGPGLPPMMPPGPPAPNTNP 573
SP G G P P PP P P
Sbjct: 1181 --SPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Score = 77.8 bits (190), Expect = 3e-14
Identities = 93/331 (28%), Positives = 117/331 (35%), Gaps = 61/331 (18%)
Query: 265 TAPAPAPTTDPWGG---PAPMAAAVPTAAPTSDPWGGP--------PVPPAADP---WGG 310
T PA P + P GG P+P A AA P GGP P PPAA P GG
Sbjct: 1219 TTPAATPPS-PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277
Query: 311 PAPTPASGDP-----WRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA 365
A P G P P+ GP+ P G P P A P+P G P + P
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK-------GSPGTPPPK 1330
Query: 366 SDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS-AGEL 424
P PA P G+P P+T ++ G PT+ SS G
Sbjct: 1331 GAPTPPAVTPPSP-KGTPTLPATTPSSKGG-------------------PTTPSSKEGPT 1370
Query: 425 ELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDL 484
A P S RG + P + P P +K P + + A
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP-KKAPATPVTREGAATPS 1429
Query: 485 DSLVSRPGPTPPG-AKASNPFLPGGGPATG--------PSVTNPF---QPAPPATLTLNQ 532
++ P TP KA P GGPAT P+VT P PAP T +
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489
Query: 533 LRLSPVPPVPGAPPTYISPLGGGPGLPPMMP 563
+ +P P P PT + + P P P
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520
Score = 67.8 bits (164), Expect = 3e-11
Identities = 95/313 (30%), Positives = 106/313 (33%), Gaps = 56/313 (17%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDP-WRPAA 325
P P+ P+ P A P AP P A P P PAS P P
Sbjct: 886 PTPSVVNLPFPKEGP-ATPAPKQAPALSMTSSSPKKARATP--APKGIPASPSPKGAPTP 942
Query: 326 PAGPSVDPWGG--TPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSP 383
PA P GG TP+P P S GG P + P PA P GG P
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA-PTPPAATPPSPKGG-P 1000
Query: 384 AKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSG 443
A PS G T P P +A A PA +P
Sbjct: 1001 ATPSPKGAPTPPAV-TPPS------------PKGSPAATPFPKGASTPPAATP-----PS 1042
Query: 444 VRGSLAEAVGSPPPAATP----TPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAK 499
+GS PAATP PT P P GP + + PTPP
Sbjct: 1043 PKGS---------PAATPLPKGAPTTPAATLPSPKGGPATPSL-------KGAPTPP--- 1083
Query: 500 ASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI----SPLGGG 555
A+ P P GGPAT PS P PPA + PP GAP T SP GG
Sbjct: 1084 AATPPSPKGGPAT-PSPKG--APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 556 PGLPPMMPPGPPA 568
PP P PA
Sbjct: 1141 ATPPPKGAPTTPA 1153
Score = 52.8 bits (125), Expect = 9e-07
Identities = 104/379 (27%), Positives = 131/379 (34%), Gaps = 92/379 (24%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAA-DPWGGPAP-----TPASG 318
++P AP T PAPM A A S P P P + DP A TPA+
Sbjct: 1488 SSPKKAPAT-----PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542
Query: 319 DPWRPAAPAGPSVDPWGGTPA-PAAGEGPT----------PDPWGSSDGGVP-------- 359
P P +V TPA P E P P S+ G P
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Query: 360 --VSGPSASDPWTPAPAFSDPWGGS-PAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT 416
V+ PS + TP PA + P PA P+ GT + P D PT
Sbjct: 1603 PAVTSPSPKEAPTP-PAVTPPSPEKGPATPAPKGTPTSP--PVTPSSLKDS-------PT 1652
Query: 417 SGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPES--- 473
S +S + VP S G G +L E + +P P +TP T PTRK P++
Sbjct: 1653 SPASV--TCKMGATVPQASKGLPAKKGPT-ALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
Query: 474 ----------------FLGPNAALVDL----------------DSLVSRPGP-TPPGAKA 500
GP + + D+ S GP PP +KA
Sbjct: 1710 SATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKA 1769
Query: 501 SNPFLPGGGPATGP---SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPG 557
S P P S + P+PP +L L SPVP +P P P PG
Sbjct: 1770 STPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP---SPVPTLP--PKQQFLP--SSPG 1822
Query: 558 LPPMMPPGPPAPNTNPFLL 576
L P P AP LL
Sbjct: 1823 LVLESPSKPLAPADEDELL 1841
Score = 50.4 bits (119), Expect = 4e-06
Identities = 90/340 (26%), Positives = 113/340 (33%), Gaps = 46/340 (13%)
Query: 253 EESSLMDLADVFTAPAPAPTT-DPWGGPAPMAAAV-PTAAPTSDPWGGPPVPPAADPWGG 310
+E +L L V TA P P AP+A V P S P P +PPA P G
Sbjct: 691 KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP--SPSLPPAGTPPGT 748
Query: 311 PAPTPASGDPWRPAAPAGPSVDPW--GGTPAPAAGEGP------TPDPWG---SSDGGVP 359
S + P P G A A+ +G +P P G S P
Sbjct: 749 KKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808
Query: 360 VSGPSASDPWTPAPAFSDPWGGSPAKPS---TNGTTAAGGFDTEPDEFSDFDRLRTALPT 416
+ ++ P TP S P SP + S N + G D+ S PT
Sbjct: 809 PTKKGSAGPDTPIGNLSSPV--SPVEASFLPENSLSFQGSKDSPATTHS---------PT 857
Query: 417 SGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRK-TPESFL 475
S G A +P A +G +P P+ P P TP
Sbjct: 858 PPSPKG----------APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 476 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL 535
P ++ +R P P G AS P G P T P+ T P PAT +
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPS--PKGAP-TPPAATPPSPKGGPATPSPKWAPT 964
Query: 536 SP--VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 573
P PP P P SP G P P PP P P
Sbjct: 965 PPAATPPSPKGGPATPSP-KGAPTPPAATPPSPKGGPATP 1003
Score = 40.8 bits (94), Expect = 0.003
Identities = 70/302 (23%), Positives = 106/302 (35%), Gaps = 22/302 (7%)
Query: 284 AAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAG 343
AA PT PP+ ++ P PT + P AP PS P +
Sbjct: 450 AAAPTTTFEVATCVSPPM--SSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP 507
Query: 344 EGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGG------F 397
P P+ + V V P+ D T PA + G+P P+ G T
Sbjct: 508 PLPDPEDLKNLPSSVLVKFPTQKDLQT-VPASLE---GAPFSPAQAGLTTKKDPTVLPLV 563
Query: 398 DTEPDEFSDFDRLRTA--LPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSP 455
P F ++ +P S + + L +P P + S + + + +V
Sbjct: 564 QAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKT 623
Query: 456 PPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPS 515
A P P K+ S + P A L+S G P AK ++ + P +
Sbjct: 624 DSYAGPDSAGPLLKS--SLITPTVAAFPLES-ADPAGVAPTTAKGTSTYTTTASPFLEGT 680
Query: 516 VTNPFQPAPPATLTLNQLRLSPVP----PVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 571
V+ + P TL L L P PV +P +PL L P +P P+P+
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL-ATLVLAPEIPKSVPSPSL 739
Query: 572 NP 573
P
Sbjct: 740 PP 741
Score = 35.4 bits (80), Expect = 0.14
Identities = 78/330 (23%), Positives = 115/330 (34%), Gaps = 38/330 (11%)
Query: 266 APAPAPTT---DPWGGPAPMAA---AVPTA----APTSDP-WGGPPVPPAADPWGGP--A 312
+P P+P+T P P P ++ A+P APT P GPP+ PAA P A
Sbjct: 65 SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124
Query: 313 P----TPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSA-SD 367
P TP+S P A A SV P P P S + +S P A S+
Sbjct: 125 PTLKGTPSSSAPLALVALAPHSVQKSSAFP-PNLLTSPPSVAVAESGSVITLSAPIAPSE 183
Query: 368 PWT-----PAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-----S 417
P T P+ +P G+P+ P T S L PT +
Sbjct: 184 PKTNLNKVPSEVVPNP-KGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIA 242
Query: 418 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGP 477
+ + + + ++PG+ + G V P + T + P + + GP
Sbjct: 243 SPQVKDTTISSVLISPQNPGSLSLKG-------PVSPPAALSLSTQSLPVVTSSQKTAGP 295
Query: 478 NAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP-ATGPSVTNPFQPAPPATLTLNQLRLS 536
N SL S P + S L GP A +T + S
Sbjct: 296 NTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRS 355
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPMMPPGP 566
+PP+P + + P + P + GP
Sbjct: 356 VIPPLPSRNEVVPATVAAFPVVAPSVDKGP 385
Score = 33.9 bits (76), Expect = 0.42
Identities = 32/133 (24%), Positives = 50/133 (37%), Gaps = 13/133 (9%)
Query: 447 SLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLP 506
S+ A+G P P P +P ++ P S + ++ S P P +S LP
Sbjct: 33 SVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALP 92
Query: 507 GG----GPATGPSVTNPFQPAPPATLTLNQLRLSPV---PPVPGAPPTYIS----PLGGG 555
G P P++ P P PA L L ++P P AP ++ +
Sbjct: 93 LGTAPEAPTFLPNLIGP--PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS 150
Query: 556 PGLPPMMPPGPPA 568
PP + PP+
Sbjct: 151 SAFPPNLLTSPPS 163
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 79.0 bits (193), Expect = 1e-14
Identities = 91/327 (27%), Positives = 121/327 (37%), Gaps = 43/327 (13%)
Query: 267 PAPAPTTDPWG-GPA-PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDP--WR 322
PA P+ DP+G PA P+ PTA PT P+ P PA P G + P +G P +
Sbjct: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFH 2227
Query: 323 PAAPAGP-----SVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSD 377
P P + DP+ P+ P+ G V G AS+P P F +
Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG-------VGGGKASEPLLSPPPFGE 2280
Query: 378 PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEV--PARS 435
K G ++ P D P+SG+ G LEL +V +
Sbjct: 2281 SRKALEVKKEELGASSP---SYGPPNLGFVDS-----PSSGTHLGGLELKTPDVFKAPLT 2332
Query: 436 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRK---TPESFLGPNAALVDLDSLVSRPG 492
P A + L PPPA P+PP+ P S+ P A L RP
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ----PPLTPRPQ 2388
Query: 493 PTPPGAKASNP--FLPGGG----PATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPP 546
P PP + + P LP PA+ S ++ P P L+ SPV P +P
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPD 2448
Query: 547 TY----ISPLGGGPGLPPMMPPGPPAP 569
Y P P P PP P P
Sbjct: 2449 PYSRPPSRPQSRDPFAPLHKPPRPQPP 2475
Score = 59.7 bits (143), Expect = 7e-09
Identities = 84/322 (26%), Positives = 114/322 (35%), Gaps = 69/322 (21%)
Query: 268 APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPA 327
+P P P P P ++P S P PP P P+PA P P A
Sbjct: 495 SPPPEESPLSPP-------PESSPFSPLEESPLSPPEESP-----PSPALETPLSPPPEA 542
Query: 328 GPSVDPWGGTP-APAAGEGPTPDPWGSS-----DGGVPVSGPSASDPWTPAPAFS---DP 378
P P+ +P +P E PT P +S P+S P P +P P S P
Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 379 WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
+ SP P + + P E S R + P S P SP +
Sbjct: 603 FEESPLSPPPEESPL-----SPPPEAS-----RLSPPPEDSP-------MSPPPEESPMS 645
Query: 439 FDMSGVRGSLAEAVG--SPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 496
R S V SPPP +P +PP ++P S P P
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPL-SPPPEESPTS-------------------PPPE 685
Query: 497 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 556
++ S P P P + P +P P P +L L SP+ P+P P + P GP
Sbjct: 686 ASRLSPP--PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP--QLCPRSEGP 741
Query: 557 GLPPM-----MPPGPPAPNTNP 573
L P + P P P+ +P
Sbjct: 742 HLSPRPEEPHLSPRPEEPHLSP 763
Score = 50.8 bits (120), Expect = 3e-06
Identities = 78/300 (26%), Positives = 103/300 (34%), Gaps = 42/300 (14%)
Query: 287 PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW------RPAAPAGPSVDPWGGTPAP 340
P PT +P V P GG + +P +P AG ++P AP
Sbjct: 377 PGDTPTDEP-DALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQ--LEAP 433
Query: 341 AAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPA---FSDPWGGSPAKPSTNGTTAAGGF 397
E P P S P+S P P +P P S P PA P +
Sbjct: 434 LNEEMPLLPPPEES----PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPL 489
Query: 398 DTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPP 457
+ P + + P S LE P SP + E SPPP
Sbjct: 490 EESPLSPPP-EESPLSPPPESSPFSPLEESPLSPPEESPPS--------PALETPLSPPP 540
Query: 458 AATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVT 517
A+P +PP ++P S P L P PP A +P P P + P
Sbjct: 541 EASPL-SPPFEESPLS--PPPEEL---------PTSPPPEASRLSP-PPEESPMSPPPEE 587
Query: 518 NPFQPAPPATLTLNQLRLSPVPPVPG----APPTYISPLGGGPGLPPMMPPGPPAPNTNP 573
+P P P A+ SP+ P P +PP S L P PM PP +P + P
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647
Score = 50.4 bits (119), Expect = 4e-06
Identities = 57/155 (36%), Positives = 64/155 (41%), Gaps = 51/155 (32%)
Query: 451 AVGSPPPAATPT-----PTPPT--RKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNP 503
A+GSPPPAA PT PT P + + FL P A V PGP PG
Sbjct: 2112 ALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSV--------PGPDSPGELFLK- 2162
Query: 504 FLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPT---YISPLGGGPGLPP 560
LP PA PS +PF AP L P P APPT Y SP G P PP
Sbjct: 2163 -LPPQVPAQVPS-QDPFGLAPAYPLE---------PRFPTAPPTYPPYPSPT-GAPAQPP 2210
Query: 561 MM-----------------PPGPP--APNT-NPFL 575
M+ PPG P P+T +PFL
Sbjct: 2211 MLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFL 2245
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/247 (28%), Positives = 89/247 (36%), Gaps = 30/247 (12%)
Query: 340 PAAGEGPT--PDPWGSSDGGVPVSGPSAS-DPWTPAPAFSD--PWG--GSPAKPSTNGTT 392
P G+ PT PD + G P G S P P P + P G G +P
Sbjct: 375 PEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPL 434
Query: 393 AAGGFDTEPDEFSDFDRLRTALPTSGS-SAGELELLAGEVPARS-PGAFDMSGVRGSLAE 450
P E S PTS A L E+PA P A +S L E
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR---PLEE 491
Query: 451 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPG--G 508
+ SPPP +P +PP +P S L +S +S P +PP P P
Sbjct: 492 SPLSPPPEESPL-SPPPESSPFSPLE--------ESPLSPPEESPPSPALETPLSPPPEA 542
Query: 509 GPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPG-APPTYISPLGGGPGLPPMMPPGPP 567
P + P +P P P +L SP P +PP SP+ P PM PP
Sbjct: 543 SPLSPPFEESPLSPPP------EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596
Query: 568 APNTNPF 574
+ PF
Sbjct: 597 SRLFPPF 603
Score = 44.3 bits (103), Expect = 3e-04
Identities = 75/277 (27%), Positives = 100/277 (36%), Gaps = 51/277 (18%)
Query: 277 GGPAPMAAAVPTAAPTSDPWGGPPVPPAA--DPWG-----GPAPT----------PASGD 319
G P+PM P A +P PPVP P G GP PT A+G+
Sbjct: 2529 GTPSPMRFTFPQAV--GEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGN 2586
Query: 320 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP---WTPAPAFS 376
+P GPS G + + P+ P + DG +P AS +P
Sbjct: 2587 FHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRE 2646
Query: 377 DPWGGSPAK------PSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGE 430
DP G + P T +G TE ++ RLR ELL +
Sbjct: 2647 DPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLR-------------ELLIRQ 2693
Query: 431 VPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSR 490
R+ + + A AVG PP + P+ P + P A D SLV
Sbjct: 2694 QIQRNTLRQEKE-TAAAAAGAVG-PPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGL 2751
Query: 491 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 527
P +K S P L GP + PS +P PPAT
Sbjct: 2752 -----PPSKLSGPIL---GPGSFPSDDRLSRPPPPAT 2780
Score = 41.2 bits (95), Expect = 0.003
Identities = 88/336 (26%), Positives = 116/336 (34%), Gaps = 46/336 (13%)
Query: 267 PAPAPTTDPW-GGPA------PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 319
P P+ P G PA P + +P P S P G P + P P P P P
Sbjct: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS-PSGEPSLSPQLMP---PDPLPPPLS 940
Query: 320 PWRPAAPAGPSVDPWGGTPAP--AAGEGPTPDPWGSSDGGVPVSGP---SASDPWTPAPA 374
P AA A P++ P G P A G+ P + P+S P + +DP P
Sbjct: 941 PIITAA-APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM 999
Query: 375 FSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 434
P GSP P A EP L+ +L S + A +
Sbjct: 1000 ILPPSPGSPVGP-------ASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052
Query: 435 SP--------GAFDMSGVRGSLAEAVGSPP-PAATPTPTPPTRKTPESFLG-----PNAA 480
SP G D + + E V P PA P+ T P +P L P A
Sbjct: 1053 SPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL-PSPMGDLSCPAPSPAPA 1111
Query: 481 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP 540
L D L P G A PG P G + + + + L+ L+PV P
Sbjct: 1112 LDDFSGLGEDTAPLD-GIDA-----PGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTP 1165
Query: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL 576
+ P + G P P P AP T P L+
Sbjct: 1166 MEVYPECKQTAGQGSPCEEQEEPRAPVAP-TPPTLI 1200
Score = 38.9 bits (89), Expect = 0.013
Identities = 83/346 (23%), Positives = 113/346 (32%), Gaps = 49/346 (14%)
Query: 268 APAPTTDPWGGP--APMAAAVPTAAPTSDPWGGPPV-PPAADPWGGPAPTPASGDPWRPA 324
+P P P P A + P +P S P P+ PP P P + P
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP---WTPAPAFSDPWGG 381
+P P + +P P A +P P S P P++ P P P
Sbjct: 669 SPLSPPPEESPTSPPPEASR-LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727
Query: 382 SPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL----------LAGEV 431
P +P + P+E R P A E L E
Sbjct: 728 LPEEPQLCPRSEGPHLSPRPEE--PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785
Query: 432 PARSPGAFD--MSGVRGSLAEAVGSPPPAATPTPTPP-----------TRKTPESFLGPN 478
P SP A +S L + + P +P P P + ++ E L P
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR 845
Query: 479 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV 538
L + +P +P K P PG PA P PP +L+ L P
Sbjct: 846 PEESHLSPELEKPPLSPRPEKP--PEEPGQCPAPEELPLFP----PPGEPSLSPLLGEPA 899
Query: 539 PPVPGAPPTYISPL--------GGGPGLPP-MMPPGPPAPNTNPFL 575
PG PP +SPL G P L P +MPP P P +P +
Sbjct: 900 LSEPGEPP--LSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII 943
Score = 37.7 bits (86), Expect = 0.029
Identities = 67/277 (24%), Positives = 88/277 (31%), Gaps = 63/277 (22%)
Query: 302 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS 361
P + +P P P + P P P + P G+ P P+ P
Sbjct: 835 PQSEEPCLSPRPEESHLSPELEKPPLSPRPEK----PPEEPGQCPAPEELPL----FPPP 886
Query: 362 GPSASDPWTPAPAFSDPWGGSPAKP-------STNGTTAAGGFDTEPDEFSD--FDRLRT 412
G + P PA S+P G P P S +G + PD +
Sbjct: 887 GEPSLSPLLGEPALSEP-GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITA 945
Query: 413 ALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPE 472
A P + S GELE G P S + + E SPPP A T
Sbjct: 946 AAPPALSPLGELEYPFGAKGDSDPE----SPLAAPILETPISPPPEANCTD--------- 992
Query: 473 SFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQ 532
P P PP +P G GP+ +P PP L Q
Sbjct: 993 ------------------PEPVPPMILPPSP-----GSPVGPASPILMEPLPPQCSPLLQ 1029
Query: 533 LRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 569
L P +PP+ SP P L P+ P P +P
Sbjct: 1030 HSLVP----QNSPPSQCSP----PAL-PLSVPSPLSP 1057
Score = 36.6 bits (83), Expect = 0.065
Identities = 42/134 (31%), Positives = 56/134 (41%), Gaps = 20/134 (14%)
Query: 449 AEAVGSPPPAATP-TPTPPTRKT----PE--SFLGPNAALVDLDSLVSRPG-----PTPP 496
++AV PP P T T P + P+ F GP + RP P PP
Sbjct: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPP 4293
Query: 497 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI-SPLGGG 555
GA ++ P L P PS +P +P P+ L S +P PPT+ +P G
Sbjct: 4294 GALSTGPVLGPVHPTPPPS--SPQEPKRPSQLPSPS---SQLPTEAQLPPTHPGTPKPQG 4348
Query: 556 PGLPPMMPPGPPAP 569
P L P PPG +P
Sbjct: 4349 PTLEP--PPGRVSP 4360
Score = 35.4 bits (80), Expect = 0.14
Identities = 51/208 (24%), Positives = 75/208 (36%), Gaps = 50/208 (24%)
Query: 187 QLQLALAMSKEEADQPPSCGP------------------EDDAQLQLALSLSRE-EHDKE 227
Q L M QPP GP + AQLQ L+ + + H
Sbjct: 4157 QPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSP 4216
Query: 228 ERIRRGDDLRLQMAIEESK--RETG-----GKEESSLMDLADV------FTAPAPAPTTD 274
++ ++ L +Q +++S+ R+T G + S L L F P P +
Sbjct: 4217 QQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276
Query: 275 PWGGPAPMAAA---VPTAAPTSDPWGGP--PVPPAADPW-----------GGPAPTPASG 318
GP P P A ++ P GP P PP + P PT A
Sbjct: 4277 LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQL 4336
Query: 319 DPWRPAAPA--GPSVDPWGGTPAPAAGE 344
P P P GP+++P G +PAA +
Sbjct: 4337 PPTHPGTPKPQGPTLEPPPGRVSPAAAQ 4364
Score = 33.9 bits (76), Expect = 0.42
Identities = 51/210 (24%), Positives = 71/210 (33%), Gaps = 17/210 (8%)
Query: 260 LADVFTAPAPAPTTD------PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 313
L+ + TA AP + P+G P AAP + P PP P P
Sbjct: 939 LSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET---PISPPPEANCTDPEP 995
Query: 314 TPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP 373
P P P +P GP+ P P P P P S PS P PA
Sbjct: 996 VPPMILPPSPGSPVGPA-SPILMEPLP-----PQCSPLLQHSLVPQNSPPSQCSP--PAL 1047
Query: 374 AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA 433
S P SP + A + E ++ S+ + + + L+ P+
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107
Query: 434 RSPGAFDMSGVRGSLAEAVGSPPPAATPTP 463
+P D SG+ A G P + P P
Sbjct: 1108 PAPALDDFSGLGEDTAPLDGIDAPGSQPEP 1137
Score = 33.5 bits (75), Expect = 0.55
Identities = 114/516 (22%), Positives = 174/516 (33%), Gaps = 102/516 (19%)
Query: 141 REERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEAD 200
R E H L K A+ S+ G E E +LQ +KE+A
Sbjct: 4455 RSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQ-GTPSNKEDAA 4513
Query: 201 --QPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLM 258
+P + P+ + L SR++ KE+ +R + L Q+ K+E SL+
Sbjct: 4514 ARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQL-----------KQELSLL 4562
Query: 259 DLADV-----FTAPAPAPTTDPWGGPAPM-----AAAVPTAAP------TSDPWGGPPVP 302
L + F+ AP + P G + + + A+PT T + PP P
Sbjct: 4563 PLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTP 4622
Query: 303 PAADP-----------WGGPAPTPASGDPWRPAAPAGPS------------VDPWGGTPA 339
P++ P G P+ G+ + AA A S +D P
Sbjct: 4623 PSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPT 4682
Query: 340 PAAGEGPTPDPWGSSDGGVPVSGPSASDPWT----PAPAFSDPWGG---------SPAKP 386
P + D P S AS P + AP F G SP P
Sbjct: 4683 PPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIP 4742
Query: 387 STNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRG 446
+ DT+P + + LP + G+ ++ + + A +++GV
Sbjct: 4743 LIPRASIPVFPDTKPYGALGLE-VPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMV 4801
Query: 447 SLAEAVGSPPPAATPT--PTPPTRKTPE----SFLGPNAALVDLDSLVSRPGPTPPGAKA 500
++AE + P + P P R E GP L+ P P K
Sbjct: 4802 AVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEG--KSPDTGPDWLKQ 4859
Query: 501 SNPFLPGGGPATGPSVTNPFQ-----PAPP---------ATLTLNQLRLSPVPPVPGAPP 546
+ LPG + + + + P PP + L + QL +P P P PP
Sbjct: 4860 FDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLS-APPPEEPSPPP 4918
Query: 547 TYISPLGGGPGLPPMMP---------PGPPAPNTNP 573
SPL P PP P PP P+ P
Sbjct: 4919 ---SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLP 4951
Score = 30.0 bits (66), Expect = 6.0
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 262 DVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW 321
DV AP P +P P+P+A + P + PT P P A P P P +S +
Sbjct: 4902 DVRQLSAPPPE-EPSPPPSPLAPS-PASPPTEPLVELPTEPLAEPPVPSPLPLASSPESA 4959
Query: 322 RPAAPAGP 329
RP A P
Sbjct: 4960 RPKPRARP 4967
Score = 29.6 bits (65), Expect = 7.9
Identities = 80/342 (23%), Positives = 114/342 (33%), Gaps = 56/342 (16%)
Query: 219 LSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWG- 277
LS+ E +K+ + +R +L ++ I+ R T +E+ TA A A P G
Sbjct: 2672 LSQTELEKQRQRQRLRELLIRQQIQ---RNTLRQEKE---------TAAAAAGAVGPPGS 2719
Query: 278 -GPAPMAAAVPTAAPTSDPWGGPP-------VPPA--ADPWGGPAPTPASGDPWRPAAPA 327
G P + A + P+ G +PP+ + P GP P+ RP PA
Sbjct: 2720 WGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPA 2779
Query: 328 GPSV------DPWGGTP-----APAAGEGPTPDP----WGSSDGGVPVS---GPSASDPW 369
PS GG+ AP G P W S SA P
Sbjct: 2780 TPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPS 2839
Query: 370 TPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
TP P GSP + G P + F LR + G G
Sbjct: 2840 TPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGG--TPFPG 2897
Query: 430 EVPARSPGAFDMS---------GVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA 480
+ P + P + +S G+RG + P+A P P P
Sbjct: 2898 QGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTL 2957
Query: 481 LVDLDSLVSRPGPTPPGAKASNPFLPGGG--PATGPSVTNPF 520
L+ LV+RP P+ NP G P P + + F
Sbjct: 2958 PTGLE-LVNRP-PSSTELGRPNPLALEAGKLPCEDPELDDDF 2997
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 74.3 bits (181), Expect = 3e-13
Identities = 104/345 (30%), Positives = 120/345 (34%), Gaps = 63/345 (18%)
Query: 277 GGPAPMAAAVPTAAPTSDPWGGPPVPPA--ADPWGGPAPTPASGDPWRPAAPAGPS---- 330
G PA A A P A P P PPA A P GG P P RP PAGP+
Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124
Query: 331 ---VDPWGG----TPAPAA---GEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWG 380
P G P PAA GP P P G + P + + + P P P G
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP-GPGPGPGPGPG 183
Query: 381 GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP-TSGSSAGELELLAGEVPARSPGAF 439
P KP+ G T + + A P S + G LL PA +PG
Sbjct: 184 PGPGKPA-----GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA-APGTV 237
Query: 440 DMS----GVRGSLAEAVGSPP-------PAATPTPTPPT-------------RKTPESFL 475
+ G A A SPP PAA P P PP T +
Sbjct: 238 IQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV 297
Query: 476 GPNAALVDLDSLVSRPGPTP-PGAKASNPFLPGGG-----PATGPSVTNP---FQPAPPA 526
P AA + S + P P P G A PG G PA G +P Q APPA
Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357
Query: 527 TLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 571
T L+ P A I P G LP PPAP T
Sbjct: 358 AQT-----LAASGPASTAASMVIGPTMQG-ALPSPAAVPPPAPGT 396
Score = 58.9 bits (141), Expect = 1e-08
Identities = 86/327 (26%), Positives = 111/327 (33%), Gaps = 58/327 (17%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGP-PVPPAADPWGGPAPTPASG-----DP 320
PAPA P GPA +AA A P P GP P P P G A +G +
Sbjct: 152 PAPAGPAKP-AGPAALAAR---AGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
Query: 321 WRPAAPA------GPS----------------VDPWGGTPAPAAGEGPTPDPWGSSDGGV 358
AAPA GP+ P+ G AP A P+P
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA-----APA 262
Query: 359 PVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSG 418
P + +A P PAPA G PA P T P + A P
Sbjct: 263 PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA------VPPPAAAQNGGSAGAAPAPA 316
Query: 419 SSAGELELLAGEVPARSPGAFDMSGVRGSLAEAV--GSPPPAATPTPTPPTRKTPESFLG 476
+AG ++G+ + A GV+ + V +PP A T + P +G
Sbjct: 317 PAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376
Query: 477 PNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT-----LTLN 531
P + + P PP A + LP G +VT P AT TL
Sbjct: 377 PT-----MQGALPSPAAVPPPAPGTPTGLPKGAAG---AVTQSLSRTPTATTSGIRATLT 428
Query: 532 QLRLSPVPPVPGAPPTYISPLGGGPGL 558
L+P P P PT I PG+
Sbjct: 429 PTVLAPRLPQPPQNPTNIQNFQLPPGM 455
Score = 57.8 bits (138), Expect = 3e-08
Identities = 93/344 (27%), Positives = 121/344 (35%), Gaps = 61/344 (17%)
Query: 266 APAPAPTTDPWGG----PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPW 321
AP T P+ G PAP A + P A + P PP PP PAP + P
Sbjct: 233 APGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP-------PAPATLARPPG 285
Query: 322 RPAAP--AGPSVDPWGGTPAPA-----AGEGPTPDPWGSSDGGV---PVSGPSASDPWTP 371
PA P A P+V P PA A AG P P P GV P G +A+ P P
Sbjct: 286 HPAGPPTAAPAVPP----PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP-AP 340
Query: 372 APAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT--------SGSSAGE 423
P A P T AA G + ++ ALP+ G+ G
Sbjct: 341 GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL 400
Query: 424 LELLAGEVP---ARSPGAFDMSGVRGSLAEAVGS---PPPAATPT-----PTPPTRKTPE 472
+ AG V +R+P A SG+R +L V + P P PT PP
Sbjct: 401 PKGAAGAVTQSLSRTPTA-TTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVR 459
Query: 473 SFLG-----PNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPAT 527
S G P AL + ++ P A P P P S AP
Sbjct: 460 SENGQLLMIPQQALAQMQ---AQAHAQPQTTMAPRPATPTSAPPVQISTVQ----APGTP 512
Query: 528 LTLNQLRLSPVPPVPGAPPTYISP---LGGGPGLPPMMPPGPPA 568
+ Q+ + + T + P L PG+ P + G A
Sbjct: 513 IIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAA 556
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 73.2 bits (178), Expect = 6e-13
Identities = 131/547 (23%), Positives = 185/547 (33%), Gaps = 95/547 (17%)
Query: 90 ERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALK 149
E+ S + +E + +D D D +D+ N E A +DE EE ++
Sbjct: 1044 EQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIV 1103
Query: 150 TKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQPP-----S 204
T + AT+SS + S + ++ P SS +EE + +EE + S
Sbjct: 1104 TSKA---EATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMAS 1160
Query: 205 CGPEDDAQ------------------LQLALSLSREEHDKEERIRRGDDLRLQMAIEESK 246
GPED Q ++ + + E EER D+ L + +EE
Sbjct: 1161 AGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPA 1220
Query: 247 RETGGKEESSLMDLADVFTAPAPA-------PTTDPWGGPA---------PMAAAVPTAA 290
EE L + +P P P P P PM +P
Sbjct: 1221 DSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQP 1280
Query: 291 PTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVD---PWGGTPAPAAGEGPT 347
P P PP PP+ P P P + D P+ P P + P + + +
Sbjct: 1281 PLPPP--RPPRPPS------PPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQS 1332
Query: 348 PDPWGSSDGGVPV-----SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPD 402
+ ++ GG P SG S S P P FS P+ + + ++GG P
Sbjct: 1333 TETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFS--------YPAPSPSLSSGGLPRTPG 1384
Query: 403 EFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAV----GSPPPA 458
F PT +G L L +P G D G LA V G P P
Sbjct: 1385 RDFSFT------PTFSEPSGPLLLPVCPLPT---GRRDERS--GPLASPVLLETGLPLPL 1433
Query: 459 ATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTN 518
P P P P A L L+ P + P P P P + S+
Sbjct: 1434 PLPLPLPLA--LPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDG 1491
Query: 519 PF-QPAPPATLTLNQLRLSPVPPVPGAPPTY------ISPLGGG-----PGLPPMMPPGP 566
P +P A L L L P P P T+ + G P LPP PP P
Sbjct: 1492 PLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPP 1551
Query: 567 PAPNTNP 573
P P P
Sbjct: 1552 PPPPVEP 1558
Score = 61.2 bits (147), Expect = 2e-09
Identities = 92/340 (27%), Positives = 119/340 (35%), Gaps = 71/340 (20%)
Query: 280 APMAAAVPTAAPTS-DPWGGPPVPPAADP----WGG-------PAPTPASGDPWRPAAPA 327
AP +P A P + + G PP PP D GG P P + G P ++PA
Sbjct: 431 APAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPA 490
Query: 328 GPSV--DPWGGTPAPAAGEGPTP-----DPWGSSD---GGVPVSGPSAS-DPWTPAPAFS 376
GP D E T +P ++ G P+S S+ P P S
Sbjct: 491 GPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNS 550
Query: 377 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 436
P P PS+ ++ G D P T LP S EL+L G P P
Sbjct: 551 QPGFRGPTPPSSR-PSSTGLEDISP----------TPLPDSDEDE-ELDLGLGPRPPPEP 598
Query: 437 GAFDMSGVRGSLAEAVGSPPPAATPT----------------------PTPPTRKTP--- 471
G D +G+ AE TPT P+ P
Sbjct: 599 GPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPK 658
Query: 472 ESFLGPNAALVDLDSLVSR--PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT 529
+ P AA V S+++ P P PPG P P P G + P P PP
Sbjct: 659 PMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPP 718
Query: 530 LNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 569
+ P PP+P APP G PP++PP PP P
Sbjct: 719 AHPAVTVPPPPLP-APP--------GVPPPPILPPLPPFP 749
Score = 48.1 bits (113), Expect = 2e-05
Identities = 68/240 (28%), Positives = 89/240 (37%), Gaps = 47/240 (19%)
Query: 168 GPPPEAEQAWPQSSGEEELQ-LQLALAMSKEEAD------QPPSCGPEDDAQLQLALSLS 220
GP P + + P S+G E++ L + EE D PP GP D A L LS
Sbjct: 556 GPTPPSSR--PSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGL-----LS 608
Query: 221 REEHDKEERIRRGDDLRLQMAIEESKRETGGKEESS--LMDLADVFTAPAPAPTTDPWGG 278
+ + + GD ++E ++ +G E S M A + +A P P G
Sbjct: 609 QTAEVALDLV--GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGA 666
Query: 279 PAPMAAAV--PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGG 336
A A +V PT P P G PP+PP P P P P +P P P + P
Sbjct: 667 AAVAAPSVLAPTL-PLPPPPGFPPLPP-------PPPPP----PPQPGFPMPPPLPPPPP 714
Query: 337 TPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-------------AFSDPWGGSP 383
P PA P P + GVP P P P P WGG P
Sbjct: 715 PPPPAHPAVTVPPPPLPAPPGVP--PPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMP 772
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/252 (25%), Positives = 84/252 (33%), Gaps = 44/252 (17%)
Query: 312 APTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP 371
+P +S P AP G + P GPTP S G+ P TP
Sbjct: 531 SPISSSSSQLSPLAPFGTNSQP--------GFRGPTPPSSRPSSTGLEDISP------TP 576
Query: 372 APAFSDP----WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSG-------SS 420
P + G P P G G ++ E + D + PTS SS
Sbjct: 577 LPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVA-LDLVGDRTPTSEKMDEGQQSS 635
Query: 421 AGELELLAGEVPARSPGAFD----MSGVRGSLAEAVGS---------PPPAATPTPTPPT 467
++E+ E+P+ + D M G+ A A S PPP P P PP
Sbjct: 636 GEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPP 695
Query: 468 RKTPE-SFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPA 526
P+ F P L P P P P LP P + P P PP
Sbjct: 696 PPPPQPGFPMPPP----LPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPG 751
Query: 527 TLTLNQLRLSPV 538
+ Q+ +S V
Sbjct: 752 LFPVMQVDMSHV 763
Score = 32.0 bits (71), Expect = 1.6
Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 33/96 (34%)
Query: 494 TPPGAKASNPFLPGGGPATG-PSVTNPFQ------PAPPATLTLN---------QLRLSP 537
TPP A+A+ PA G S +P+Q P PP T + R +P
Sbjct: 381 TPPPAQAT--------PAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAP 432
Query: 538 VPP-VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTN 572
PP +P A P P PPGPP P+TN
Sbjct: 433 APPPLPPAEPLAKEK--------PGTPPGPPPPDTN 460
>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
Length = 411
Score = 73.2 bits (178), Expect = 6e-13
Identities = 97/365 (26%), Positives = 136/365 (37%), Gaps = 49/365 (13%)
Query: 226 KEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAA 285
K R + + RLQ + + G ++ + V A A AP P G + AA
Sbjct: 14 KNRRAKLARERRLQQQPQRVPGQRGRGARAAPL----VPAASASAPQRGPSG---ILPAA 66
Query: 286 VPTAAPTSDPWGGP------PVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPA 339
PT WGGP +P A P GP P P G PA GP G P
Sbjct: 67 EPTICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAPIPG----PAQIPGPLP---GSIPG 119
Query: 340 PAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFD- 398
P G P P + P+ GP + P P F P G + P+ +G F
Sbjct: 120 PIPGPAQIPSPIPA-----PIPGPISGPVQIPGP-FRGPIPGPISGPAPIPGPISGPFSG 173
Query: 399 TEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPA 458
P + P SG G + + +P PG + G ++ P P
Sbjct: 174 PNPGPIPGPNPGPIPGPISGPIPGPISV---PIPGPIPGP-----ISGPISGPNPGPIPG 225
Query: 459 ATPTPT--PPTRKTPESFLGPNAALV--DLDSLVSRPGPTPPGAKASNPFLPGGGPATGP 514
P P P P GPN L+ + +S PGP G S +PG G GP
Sbjct: 226 PIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPI-IGPIPSPAQIPGPGRLQGP 284
Query: 515 S-VTNPFQPAPPATLTLNQLRLSPVPPVPGAPP---TYISPLGGGPGLPPMMPPGPPAPN 570
+ +P + P +L L+P+ PG+ P + +P+ G LP P P +P+
Sbjct: 285 GPILSPGRMRSPGSLP----GLAPILG-PGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPD 339
Query: 571 TNPFL 575
+ FL
Sbjct: 340 ASDFL 344
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/312 (29%), Positives = 118/312 (37%), Gaps = 51/312 (16%)
Query: 279 PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPT--PASGDPWRPAAPAGP------S 330
P+P A P+A + +A P PA + A G P PA P+ P +
Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270
Query: 331 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP-APAFSDPWGGSPAKPSTN 389
+ P TP P P P SS P++ PS S P +P AP PA P +
Sbjct: 271 LRPPQVTP-PRKDAAPALGPLSSS----PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325
Query: 390 GTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLA 449
TT+ G + LP+ L LA P P +L
Sbjct: 326 ATTSLGS--------PTLQATHSFLPSP-----PLSPLATPPPQAPPAL--------ALP 364
Query: 450 EAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGG 509
P P A+P +P +P++ PNA V L P P+PP PF P
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQA---PNALAVHLLQAPFSPPPSPP---VQAPFSPPAS 418
Query: 510 PATGPSVTNPFQPAPPATLTLNQLRLSPVPPV-PGAPPTYISPLGGGPGL--PPMM---- 562
P PS T P Q APP +L L++ P PP P P+ P P L PP+
Sbjct: 419 PPVSPSATPPSQ-APP-SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476
Query: 563 -PPGPPAPNTNP 573
P PPA T P
Sbjct: 477 PPQAPPALATPP 488
Score = 64.7 bits (156), Expect = 2e-10
Identities = 89/318 (27%), Positives = 116/318 (36%), Gaps = 40/318 (12%)
Query: 266 APAPAP-TTDPWGGPAPMAAAVPTAAPTSDPWGGPP-VPPAADPWGGPAPTPASGDPWRP 323
APA P ++ P P+P A P+A P+ PP PP+ +PT + + P
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343
Query: 324 AAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP----APAFSDPW 379
+ P P P P PA P P S P+S + P P P+
Sbjct: 344 SPPLSPLATPPPQAP-PALALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401
Query: 380 GGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAF 439
P+ P + P +A P S + L +VP P +
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSP----------SATPPS-QAPPSLAAPPLQVPPSPPASP 450
Query: 440 DMSGVRGSLAEAVGSPPPAATP---TPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 496
MS S +PPP A P PP + P P AL + S PG P
Sbjct: 451 PMS---PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA--SFPGQAPF 505
Query: 497 GAKASNPFLP--GGGPATGPSVTNPF---QPAPPATLTLNQLRLSPVPPVPGAPPTYISP 551
AS P P P P + P P+PPA+ TL R PP PG P T +S
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTPG-PDTSVS- 560
Query: 552 LGGGPGLPPMMPPGPPAP 569
GP L + PGPP P
Sbjct: 561 ---GPRLTLALAPGPPPP 575
Score = 63.5 bits (153), Expect = 5e-10
Identities = 92/320 (28%), Positives = 113/320 (35%), Gaps = 47/320 (14%)
Query: 279 PAPMAAAVPTAAPTSDPWGGPPVPPAADPWGG--------PAPTPASGDPWRPAAPAGPS 330
PA A + T P P PPV PAA G P A G + P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 331 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS-ASDPWTPAPAFSDPWGGSPAKPSTN 389
P + PA+G G P ++ G PVS P AS P P G + S
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPL-----GQKGLRISAE 130
Query: 390 GTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR-SPGAFDMSGVRGSL 448
T A G P R+AL SAG +G P SP S G+
Sbjct: 131 ETVARGKATEAPK--------RSAL-----SAGARRDTSGPTPGTPSPAMARRSRAAGT- 176
Query: 449 AEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT-------PPGAKAS 501
VG P PA + P PPT +S + S +R P+ P S
Sbjct: 177 --EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234
Query: 502 NPFLPGGGPA-TGPSVTN----PFQPAPPATLTLNQLRLSPV-PPVPGAPPTYISPLGGG 555
+ P PA +GPS P P+ P L LR V PP A P + PL
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA-LGPLSSS 293
Query: 556 PGLPPMMPPGPPAPNTNPFL 575
P P P PP+P+ P L
Sbjct: 294 PLATP-SPSAPPSPSAPPSL 312
Score = 57.4 bits (137), Expect = 4e-08
Identities = 77/314 (24%), Positives = 103/314 (32%), Gaps = 47/314 (14%)
Query: 266 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA- 324
+P +P P P+P A P+ PP PP P+ PA P S P+
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGP----SASDPWTPAPAFSDPWG 380
AP + P P+P A +P P++ P + P P + P
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 490
Query: 381 GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA-- 438
P+ P+ + G P L T P + L P SP
Sbjct: 491 ALPSPPA----SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546
Query: 439 ----------FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLV 488
+SG R +LA A G PP PP+R + GP DL
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPP--------PPSRSPSSTLSGP-----DLAGHS 593
Query: 489 SRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPV-----PG 543
S TP + + P GG A P PA + P PP+ PG
Sbjct: 594 SSATSTPEELRGYDSG-PEGGAAASPPPDAELAACHPAAWS-----RGPAPPLAFRGAPG 647
Query: 544 APPTYISPLGGGPG 557
AP + P GPG
Sbjct: 648 APLPW--PPATGPG 659
Score = 39.7 bits (91), Expect = 0.008
Identities = 40/141 (28%), Positives = 50/141 (35%), Gaps = 19/141 (13%)
Query: 266 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAAD--PWGGPAPTPASGDPWRP 323
A AP P P P+ + A +S P D P GG A +P
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626
Query: 324 AAPAGPSVDPWGGTPAPAA---GEGPTPDPW------GSSDGGVPVSGPSASDPWTPAPA 374
PA W PAP G P PW GS+DG + + TPAP
Sbjct: 627 CHPAA-----WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681
Query: 375 FSDPWGGSPAKPSTNGTTAAG 395
DP P+ ++ G AAG
Sbjct: 682 ALDP---GPSPGTSGGKAAAG 699
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 71.6 bits (174), Expect = 2e-12
Identities = 81/329 (24%), Positives = 114/329 (34%), Gaps = 71/329 (21%)
Query: 265 TAPAPAPTTD----PWGGPAPMAAAVPTAAPTSDPWGGPPV------PPAADPWGGPAPT 314
T P+P PT+ P P+P T PT+ P PP+ PP P P T
Sbjct: 1404 TTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTP--SPPITTTTTPPPTTTP-SPPIST 1460
Query: 315 PASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPA 374
+ P +P + P TP+P TP P + S P+ + PA
Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP------SPPTTTPITPPAST 1514
Query: 375 FSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 434
+ P +P+ P+T TT P + PTS ++ P
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-----PTSTTTLP---------PTT 1560
Query: 435 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 494
+P SPPP T TP P T +P + P+ + + P+
Sbjct: 1561 TP-----------------SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603
Query: 495 PPGA------KASNPFLPGGGPATGPSVTNPF----QPAPPATLTLNQLRLSPVPPVPGA 544
PP + P P P T P+ T P+PP T T +P P +
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT-----TTPPPTTTPS 1658
Query: 545 PPTYISPLGGGPGLPPMMPPGPPAPNTNP 573
PPT +P PP+ P P T P
Sbjct: 1659 PPTTTTP------SPPITTTTTPPPTTTP 1681
Score = 65.1 bits (157), Expect = 2e-10
Identities = 75/321 (23%), Positives = 108/321 (33%), Gaps = 56/321 (17%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T P+P PTT P PA PT P+ PP P P+P + P P
Sbjct: 1498 TTPSP-PTTTPITPPASTTTLPPTTTPS------PPTTTTTTPPPTTTPSPPTTTPITP- 1549
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP----AFSDPWG 380
P + P TP+P TP P + PS TP+P + P
Sbjct: 1550 -PTSTTTLPPTTTPSPPPTTTTTPPP---------TTTPSPPTTTTPSPPTITTTTPPPT 1599
Query: 381 GSPAKPSTNGTTAAGGFDTEPDEFSDFD--RLRTALPTSGSSAGELELLAGEVPARSPGA 438
+P+ P+T TT P + T LP + + + P +P
Sbjct: 1600 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP-- 1657
Query: 439 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDS----LVSRPGPT 494
SPP TP+P T TP P++ + S ++ P PT
Sbjct: 1658 ---------------SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPT 1702
Query: 495 P-PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLG 553
P + + P P T P+P T + ++ +PP + P +PL
Sbjct: 1703 TTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL- 1761
Query: 554 GGPGLPPMMPPGPPAPNTNPF 574
PP P +PF
Sbjct: 1762 ---------PPSITPPTFSPF 1773
Score = 45.1 bits (105), Expect = 2e-04
Identities = 75/338 (22%), Positives = 103/338 (30%), Gaps = 37/338 (10%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3984
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3985 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4041
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPAATP-------TPTPPTRKTPESFLGPNAALV 482
+ P +P + G+ P TP TPTP TP P +
Sbjct: 4102 QTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPI 4155
Query: 483 DLDSLVSRPGPTPPGAKA--SNPFLPGGG--PATGPSVTNPFQPAPPATLTLNQLRLSPV 538
+ V+ P PTP G + + P P P+ T P +T + +L S
Sbjct: 4156 TTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNP 4214
Query: 539 PPVPGAPPT---YISPLGGGPGLPPMMPPGPPAPNTNP 573
PP P T SPL L +PP +T P
Sbjct: 4215 PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAP 4252
Score = 43.9 bits (102), Expect = 4e-04
Identities = 73/342 (21%), Positives = 103/342 (30%), Gaps = 42/342 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWR 322
+ T P+P TT P ++ T T P PP P TP+
Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744
Query: 323 PAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPA--PAFSDPWG 380
P + P TP P + PT P+ ++ P W + P F P G
Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804
Query: 381 GSPAKPSTNGTTAAGGFDTEPDEFSD--FDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
+ G A + D +L + S + L+ + G
Sbjct: 1805 DTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVS----VGLICKNEDQKPGGV 1860
Query: 439 FDMS-----GVRGSLAEAVGSPPPAATPT---PTPPT------------RKTPESFLGPN 478
M+ + E V P T T PTPPT TP P
Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT 1920
Query: 479 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQ 532
+ + V+ P PTP G + P P T + P P P T T
Sbjct: 1921 TTPITTTTTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTT 1973
Query: 533 LRLSPVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
++P P G +P+ + P P G P T P
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015
Score = 42.4 bits (98), Expect = 0.001
Identities = 58/284 (20%), Positives = 78/284 (27%), Gaps = 11/284 (3%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4076
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 4077 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4133
Query: 376 SDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 435
+ P+ T T T PT+ + P +
Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4193
Query: 436 PGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP 495
+AE S PP + TP +R T L L + P
Sbjct: 4194 QTGPPTHTSTAPIAELTTSNPPPESSTPQT-SRSTSSPLTESTTLLSTLPPAIEMTSTAP 4252
Query: 496 PGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP 539
P + GG + P T P P T +P P
Sbjct: 4253 PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP 4296
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 1924 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1983
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 1984 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2040
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2100
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 2101 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2160
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 2161 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2207
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2039 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2098
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2099 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2156 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2215
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 2216 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2275
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 2276 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2322
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2213
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2214 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2330
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 2331 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 2391 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2437
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2269 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2328
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2329 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2505
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 2506 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2552
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2443
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2444 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2560
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 2561 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2620
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 2621 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2667
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2499 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2558
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2559 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2675
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 2676 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2735
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 2736 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2782
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2673
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2674 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2850
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 2851 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 2897
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2788
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2789 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 2966 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3012
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2844 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2903
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 2904 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3080
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 3081 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3127
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3018
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3019 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3195
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 3196 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3242
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3133
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3134 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3250
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3310
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 3311 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3357
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3189 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3248
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3249 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3425
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 3426 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3472
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3363
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3364 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3480
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3540
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 3541 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3587
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3419 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3478
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3479 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3595
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3596 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3655
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 3656 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3702
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3534 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3593
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3594 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3770
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 3771 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3817
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3649 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3708
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3709 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3765
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3826 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3885
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 3886 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 3932
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970
Score = 42.0 bits (97), Expect = 0.002
Identities = 71/338 (21%), Positives = 97/338 (28%), Gaps = 43/338 (12%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3823
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3824 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3940
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 3941 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4000
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 4001 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 4047
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
P P G +P+ + P P G P T P
Sbjct: 4048 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085
Score = 39.3 bits (90), Expect = 0.010
Identities = 70/337 (20%), Positives = 96/337 (28%), Gaps = 44/337 (13%)
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAVPTAA---PTSDPWGGPP---VPPAADPWGGPAPTPA 316
+ T PT P G P + T PT P G P P PTP
Sbjct: 3879 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3938
Query: 317 SGD-PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P +V P TP P + PT P ++ P P+ + T P
Sbjct: 3939 GTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3995
Query: 376 SD------PWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAG 429
+ P P+T T P T + T+ +
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4055
Query: 430 EVPARSPGAFDMSGVRGSLAEAVGSPPPA-------ATPTPTPPTRKTPESFLGPNAALV 482
+ P +P + +P TPTPTP +TP + V
Sbjct: 4056 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4115
Query: 483 DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQLRLS 536
P PTP G + P P T + P P P T T ++
Sbjct: 4116 -------TPTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVT 4162
Query: 537 PVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 573
P P G +P+ + P P P T P
Sbjct: 4163 PTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTGP 4197
Score = 38.5 bits (88), Expect = 0.017
Identities = 78/349 (22%), Positives = 111/349 (31%), Gaps = 51/349 (14%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPAS--GDPWR 322
T P+P TT P PT P+S P P P TP+S
Sbjct: 1655 TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714
Query: 323 PAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSDGGVP---VSGPSASDPWTPA---PAF 375
P++ PS P TP+P TP P ++ +P S P + P P+ P F
Sbjct: 1715 PSSTTTPSPPPTTMTTPSPTT----TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTF 1770
Query: 376 SDPWGGSPAKPSTNGTTAAGGFDTEPDEF----SDFDRLRTAL-PTSGSSAGELELLAGE 430
S +P P G D+ F D + + P ++ + +
Sbjct: 1771 SPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPD 1830
Query: 431 VPARSPGAFDMSGVR-GSLAEAVGSPPPAATP------------------TPTPPTRKTP 471
VP G + V G + + P P PT T T
Sbjct: 1831 VPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTT 1890
Query: 472 ESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT-- 529
E+ P + + V+ P PTP G + P P T + P P P T T
Sbjct: 1891 ENPTPPTTTPITTTTTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPT 1943
Query: 530 ----LNQLRLSPVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
++P P G +P+ + P P G P T P
Sbjct: 1944 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992
Score = 36.2 bits (82), Expect = 0.084
Identities = 59/281 (20%), Positives = 84/281 (29%), Gaps = 40/281 (14%)
Query: 313 PTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPA 372
PTP + P P TP P + PT P ++ P P+ + T
Sbjct: 1893 PTPPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1945
Query: 373 PAFS------DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL 426
P + P P+T T P T + T+ +
Sbjct: 1946 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2005
Query: 427 LAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATP-------TPTPPTRKTPESFLGPNA 479
+ P +P + G+ P TP TPTP TP P
Sbjct: 2006 TGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTT 2059
Query: 480 ALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLT------LNQL 533
+ + V+ P PTP G + P P T + P P P T T
Sbjct: 2060 TPITTTTTVT-PTPTPTGTQT-----PTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTT 2112
Query: 534 RLSPVPPVPGAPPTYISPLGGGPGLPPM-MPPGPPAPNTNP 573
++P P G +P+ + P P G P T P
Sbjct: 2113 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 71.6 bits (174), Expect = 2e-12
Identities = 88/355 (24%), Positives = 117/355 (32%), Gaps = 65/355 (18%)
Query: 264 FTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP---AADPWGGPAPTPASGDP 320
F +P T P+ A+ P + P P P PP + P P +P + P
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488
Query: 321 WR---------PAAP---------------AGPSVD-PWGGTPAPAAGEGPTPDPWGSSD 355
+ P AP A PS+ P P P+ P
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 356 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 415
P++ P P PAP P P+ +T T P + + P
Sbjct: 549 ASAPLTTPHLETPPCPAPC---PLQAPPSPLTTPPPETPSSIATPPPQAPP---ALASPP 602
Query: 416 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL 475
G + L LA P P +L P P A+P +P +P++
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXL--------ALPPLQAPPSPPASPPLSPLATPSPQA-- 652
Query: 476 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ-------------P 522
PNA V L P P+PP PF P P PS T P Q P
Sbjct: 653 -PNALAVHLLQAPFSPPPSPP---VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 708
Query: 523 APPATLTLNQLRLSP--VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFL 575
+PPA+ ++ P PP APP + P P PPM P P P P L
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPP--SPPASPPMSPSATPPPRVPPLL 761
Score = 65.1 bits (157), Expect = 2e-10
Identities = 88/329 (26%), Positives = 108/329 (32%), Gaps = 82/329 (24%)
Query: 256 SLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTP 315
+L LA A AP T P P A P AP S P P P TP
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS---------PLTTP---PPETP 584
Query: 316 ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
+S P AP + P G P+P TP P +P P A
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP-----------PLQAP 633
Query: 376 SDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARS 435
P P P L T P + ++ L A P S
Sbjct: 634 PSPPASPPLSP-----------------------LATPSPQAPNALAVHLLQAPFSPPPS 670
Query: 436 PGAFDMSGVRGSLAEAVGSPP--PAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGP 493
P +A SPP P +P+ TPP++ P SL + P
Sbjct: 671 PP-----------VQAPFSPPASPPVSPSATPPSQAPP--------------SLAAPPLQ 705
Query: 494 TPPGAKASNPFLPGGGP---ATGPSVTNPFQ--PAPPATLTLNQLRLSP--VPPVPGAPP 546
PP AS P P P A P P Q P+PPA+ ++ P VPP+ APP
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 547 TYISPLGGGPGLPPMMPPGPPAPNTNPFL 575
+ P P PM P P P P L
Sbjct: 766 LQVPP--SPPASLPMSPLAKPPPQAPPAL 792
Score = 65.1 bits (157), Expect = 2e-10
Identities = 80/311 (25%), Positives = 101/311 (32%), Gaps = 69/311 (22%)
Query: 266 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA- 324
+P +P P P+P A P+ PP PP P+ PA P S P+
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPA 384
AP + P P+P A +P P++ P P P+P S P S
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSAT 752
Query: 385 KPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGV 444
P L A P +VP P + MS
Sbjct: 753 PPPR------------------VPPLLAAPPL-------------QVPPSPPASLPMS-- 779
Query: 445 RGSLAEAVGSPPPAATPT-PTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNP 503
+ PPP A P TPP + P P A+ PG P AS P
Sbjct: 780 ------PLAKPPPQAPPALATPPLQALPS----PPASF---------PGQAPFSPSASLP 820
Query: 504 FLPGGGPA--TGPSVTNPF---QPAPPATLTLNQLRLSPVPPVPGAPPTYISP-----LG 553
P P P + P P+PPA+ TL R PP PG + P L
Sbjct: 821 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALA 877
Query: 554 GGPGLPPMMPP 564
GP PP P
Sbjct: 878 PGPPPPPSRSP 888
Score = 60.8 bits (146), Expect = 3e-09
Identities = 82/324 (25%), Positives = 110/324 (33%), Gaps = 41/324 (12%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGP--APTPASGDPWRPA 324
PA P + P P P+A P+A P+ P PPA P P TP P P+
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTL---PSPPATPPSQAPPSMTTPPMQAP--PS 382
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDP---WTPAPAFSDPWGG 381
P + +P+ P+P S + P+ T +P +
Sbjct: 383 LQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT 442
Query: 382 SPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDM 441
SP++P++ T PD L+ L S + L P SP
Sbjct: 443 SPSRPAS----------TPPDS----PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488
Query: 442 SGVRGSLAEAVGSPPPAATPTPTPPTRKT--PESFLGPNAALVDLDSLVSRPGPTPPGAK 499
SLA P ++ P T+ + P S P A+L L + P PP
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT-TPPLENLPSLAPP--- 544
Query: 500 ASNPFLPGGGPATGPSVTNPFQPAP--------PATLTLNQLRLSPVPPVPGAPPTYISP 551
P P T P + P PAP P T + S P P APP SP
Sbjct: 545 ---PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601
Query: 552 LGGGPGLPPMMPPGPPAPNTNPFL 575
G PP+ P P P P L
Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXL 625
Score = 60.1 bits (144), Expect = 5e-09
Identities = 95/347 (27%), Positives = 125/347 (36%), Gaps = 44/347 (12%)
Query: 265 TAPAPAP---TTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGG--PAPTPASGD 319
T A AP T P G P P P A G P A+ GG A P S
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 320 PWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPS-ASDPWTPAPAFSDP 378
P AG S P PA+G G P ++ G PVS P AS P P
Sbjct: 76 RAGPTRSAGTSSRNPASRP-PASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPL---- 129
Query: 379 WGGSPAKPSTNGTTAAGGFDTEPDE--FSDFDRLRTALPTSGSSAGEL---ELLAGE--- 430
G + S T A G P S R T+ PT G+ + + AG
Sbjct: 130 -GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 431 VPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLG----PNAALVDLDS 486
+P +P A G ++V S +T P+P R+ P + G + +L +
Sbjct: 189 LPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 487 LVSRPGPTPPGAKA--------SNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLS-- 536
+S P + P A+ S P G P VT P + A PA L+ L+
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 537 --------PVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFL 575
PVPP A + L P L +P PP+P+ P L
Sbjct: 308 SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
Score = 56.2 bits (134), Expect = 8e-08
Identities = 77/309 (24%), Positives = 110/309 (35%), Gaps = 40/309 (12%)
Query: 266 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWR--P 323
+P +P+ P P AA P P S P PP+ P+A P AP P + P + P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATP-PPQAPPPLAAPPLQVPP 739
Query: 324 AAPAGPSVDPWGGTPA---PAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWG 380
+ PA P + P P P P P S +P+S + P P + P
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLPMSPLAKPPPQAPPALATPPLQ 798
Query: 381 GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA-- 438
P+ P++ G P L T P + L P SP
Sbjct: 799 ALPSPPAS----FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854
Query: 439 ----------FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLV 488
+SG R +LA A G PPP P+ +P + + G +++ +
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPP---PSRSPSSTLSGPDLAGHSSSATSTPEEL 911
Query: 489 SRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTY 548
P G A++P A P+ + PAPP R +P P+P P T
Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLA-----FRGAPGAPLPWPPAT- 964
Query: 549 ISPLGGGPG 557
GPG
Sbjct: 965 ------GPG 967
Score = 41.2 bits (95), Expect = 0.003
Identities = 80/300 (26%), Positives = 103/300 (34%), Gaps = 49/300 (16%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAP 326
P+P P + P P +A++P + + P PPV A P+P PAS P P
Sbjct: 801 PSP-PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAPRRP 858
Query: 327 AGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKP 386
P D P P P P S +SGP D G S +
Sbjct: 859 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP-------------DLAGHSSSAT 905
Query: 387 STNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAG---ELELLAGEVPARSPGAFDMSG 443
ST P+E +D + P G++A + EL A A S G
Sbjct: 906 ST------------PEELRGYD----SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 949
Query: 444 VRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNP 503
RG A P P AT + T GP +A +L P P G KA+
Sbjct: 950 FRG--APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA-- 1005
Query: 504 FLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP------VPGAPPTYISPLGGGPG 557
G G S +P Q A L L L+ S V + A GGGPG
Sbjct: 1006 ----AGAGAGASSRSPKQ-ARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG 1060
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 71.2 bits (173), Expect = 2e-12
Identities = 85/360 (23%), Positives = 122/360 (33%), Gaps = 57/360 (15%)
Query: 265 TAPAPAPTTDPWGGPA------PMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASG 318
++P P P + P P P+++++P + PT+ P P P P P ASG
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLP--APASAPLTIPISAPLTVSASG 1469
Query: 319 D--------PWRPAAPAG---PSVDPWGGTPAPAA---GEGPTPDPWGSSDGGVPV---- 360
P P PA PS+ P G +P+ +A G P S G P+
Sbjct: 1470 PALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAP 1529
Query: 361 -----------SGPSASDPWTPAPAFSDPWGGSPAKPSTNGT---TAAGGFDTEPDEFSD 406
P+ S PA A + P+ +P + A+ +
Sbjct: 1530 TSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589
Query: 407 FDRLRTA------------LPTSGSSAGELELLAGE---VPARSPGAFDMSGVRGSLAEA 451
+TA LP S G +LA VP +P + G + A
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSS--TPGTSLASASP 1647
Query: 452 VGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPA 511
V +P P P+ T P P+ A +L PT G+ S G G
Sbjct: 1648 VPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNP 1707
Query: 512 TGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 571
GP T P ++L + + P P PT L P L P P GP +T
Sbjct: 1708 QGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHT 1767
Score = 64.3 bits (155), Expect = 3e-10
Identities = 86/343 (25%), Positives = 121/343 (35%), Gaps = 51/343 (14%)
Query: 260 LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 319
L V P P P P P+ +P + S GPP+ PA+ P P P
Sbjct: 1019 LGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRP-----PGPVLLP 1073
Query: 320 PWRPAAPAGPSVDP-----WGGT---PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP 371
P +P + + P V P GT P P PTP P S P T
Sbjct: 1074 PLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTV 1133
Query: 372 APAFSDPWGGSPAKPSTNGTTAAGGFDT-------EPDEFSDFDRLRTALPTSG-SSAGE 423
P ++ P PA +T TT A T P ++ LP+ S G+
Sbjct: 1134 PPGYTFP----PAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQ 1189
Query: 424 LELLAGEVPARSPGA----FDMSGVRGSLAE------AVGSPPPAATPTPTPPTRKTPES 473
L LA A + G+ F + G + +L AVG P P +
Sbjct: 1190 LASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHH 1249
Query: 474 FLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAP----PATLT 529
+ A + + ++ PGPTP LP P+T P+ T P P T+
Sbjct: 1250 LISQPAHVALIQAVAPTPGPTPVSV------LPSSTPSTTPAPTGLSLPLAANQVPPTMV 1303
Query: 530 LNQ------LRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGP 566
N +R +P + PP +P GLP ++ P P
Sbjct: 1304 NNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRP 1346
Score = 52.0 bits (123), Expect = 1e-06
Identities = 83/306 (27%), Positives = 108/306 (35%), Gaps = 59/306 (19%)
Query: 278 GPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGT 337
G AP+ + P P+S P GP P P P +P S P + + P P T
Sbjct: 1391 GAAPLTISSPLHVPSSLP--GPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVP---T 1445
Query: 338 PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTP-----APAFSDPWGGSPAKPSTNGTT 392
PA P P S+ V SGP+ TP PA P +P+ S + +
Sbjct: 1446 TLPAPASAPLTIPI-SAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASA 1504
Query: 393 AAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAE 450
G T P S L PTS G +A PA SP A
Sbjct: 1505 LTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVA---PACSPVLVP--------AS 1553
Query: 451 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP 510
A+ SP P+A P P P S L P ++ + P P P
Sbjct: 1554 ALASPFPSA-PNPAP----AQASLLAPASSA---------------SQALATPLAPMAAP 1593
Query: 511 ATGPSVTNPFQPAPPATLTLNQLRLSPVP---PVPGAPPTYISPLGGGPGLPPMMPPGPP 567
T ++ P PAPP L+P+P P PGA P S P + P PG
Sbjct: 1594 QT--AILAP-SPAPP---------LAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTS 1641
Query: 568 APNTNP 573
+ +P
Sbjct: 1642 LASASP 1647
Score = 51.6 bits (122), Expect = 2e-06
Identities = 96/350 (27%), Positives = 120/350 (34%), Gaps = 77/350 (22%)
Query: 249 TGGKEESSLMDLADVFTAPAPAPTTDPWGGP---APMAAAVPTAAPTSDPWGGPPVPPA- 304
+G +S + L + TAP+ + + P G P AP ++ VP T P P + PA
Sbjct: 1496 SGASPSASALTLG-LATAPSLSSSQTP-GHPLLLAPTSSHVPGLNSTVAPACSPVLVPAS 1553
Query: 305 --ADPW-GGPAPTPASGDPWRPAA--------PAGPSVDPWGGTPAPAAGEGPTPDP-WG 352
A P+ P P PA PA+ P P P AP+ P P
Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLA 1613
Query: 353 SSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTE-PDEFSDFDRLR 411
S G PV S TP P A ST GT+ A P +
Sbjct: 1614 PSPGAAPVLASSQ----TPVPVM--------APSSTPGTSLASASPVPAPTPVLAPSSTQ 1661
Query: 412 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAAT----------P 461
T LP S P SP + + +LA +G P+ T P
Sbjct: 1662 TMLPAPVPS-----------PLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGP 1710
Query: 462 TPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ 521
PT TP S L P A +L PGP P G + P P P+ +P
Sbjct: 1711 FPTQTLSLTPASSLVPTPA----QTLSLAPGP-PLGPTQTLSLAPA--PPLAPA--SPVG 1761
Query: 522 PAPPATLTL---------------NQLRLSPVPPVPGAPPTYISPLGGGP 556
PAP TLTL L LSP PVP P L P
Sbjct: 1762 PAPAHTLTLAPASSSASLLAPASVQTLTLSPA-PVPTLGPAAAQTLALAP 1810
Score = 47.8 bits (112), Expect = 3e-05
Identities = 71/273 (26%), Positives = 99/273 (36%), Gaps = 42/273 (15%)
Query: 260 LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADP-WGGPAPTP--- 315
LA PAP P P + A VP+ P+ + PA P GG +P+
Sbjct: 1642 LASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLS 1701
Query: 316 -ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP- 373
+G+P P S+ PA+ PTP S G P+ GP+ + PAP
Sbjct: 1702 LGTGNPQGPFPTQTLSL-------TPASSLVPTPAQTLSLAPGPPL-GPTQTLSLAPAPP 1753
Query: 374 -AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVP 432
A + P G +PA T ++ P +PT G +A + LA
Sbjct: 1754 LAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALA-PAS 1812
Query: 433 ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPG 492
+SP S A ++ A P P + P S P D+L R G
Sbjct: 1813 TQSP---------ASQASSLVVSASGAAPLPVTMVSRLPVSKDEP-------DTLTLRSG 1856
Query: 493 PTPPGAKASNPFLPGGGPATGPSVTNPFQPAPP 525
P P + A++ GGP QP PP
Sbjct: 1857 PPSPPSTATS----FGGPRPRR------QPPPP 1879
Score = 47.0 bits (110), Expect = 5e-05
Identities = 71/258 (27%), Positives = 100/258 (38%), Gaps = 36/258 (13%)
Query: 311 PAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGV--------PVSG 362
P PTP S P++ + P G + AA + P P ++ GV P G
Sbjct: 1267 PGPTPVSV---LPSSTPSTTPAPTGLSLPLAANQVP---PTMVNNTGVVKIVVRQAPRDG 1320
Query: 363 PSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAG 422
+ P PAP P G PA + T G T R +PT
Sbjct: 1321 LTPVPPLAPAPR--PPSSGLPAVLNPRPTLTPGRLPTPT-----LGTARAPMPTPTLVRP 1373
Query: 423 ELELL---AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNA 479
L+L+ + EV A +PGA ++ + L P PA++P P P +P + +
Sbjct: 1374 LLKLVHSPSPEVSASAPGAAPLT-ISSPLHVPSSLPGPASSPMPIP--NSSPLASPVSST 1430
Query: 480 ALVDLDSLVSRPGPTPPGAKASNPF-LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV 538
V L S + PT A AS P +P P T + PA LT L+PV
Sbjct: 1431 VSVPLSSSLPISVPTTLPAPASAPLTIPISAPLT-------VSASGPALLTSVTPPLAPV 1483
Query: 539 PPVPGAPPTYISPLGGGP 556
P PP+ ++P G P
Sbjct: 1484 VPAAPGPPS-LAPSGASP 1500
Score = 38.1 bits (87), Expect = 0.022
Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 21/140 (15%)
Query: 436 PGAFDMSGVRGSLAEAVGS---PPPAA--TPTPTPPTRKTPESFLGPNAALVDLDSLVSR 490
PG +RG+ AE G+ P +A T + T P R +P P A R
Sbjct: 2391 PGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPA--------PR 2442
Query: 491 PGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYIS 550
P PTP A A+ P L V+ P + P +T+ + + P PP P P S
Sbjct: 2443 PRPTPASAPAAIPAL------VPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSS 2496
Query: 551 PLGGGPG--LPPMMPPGPPA 568
P P PP PPA
Sbjct: 2497 PACTPPPACTPPPAHTPPPA 2516
Score = 36.2 bits (82), Expect = 0.084
Identities = 80/317 (25%), Positives = 99/317 (31%), Gaps = 36/317 (11%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTS------DPWGGPPVPPAADPWGGPAPTPASGDP 320
PA AP P P P++A VP +AP PP P P PA TP
Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACT 2506
Query: 321 WRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS-GPSASDPWTPAPAFSDPW 379
P A P TP+ GP P +S +P+ P A A A + P
Sbjct: 2507 -PPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAE---LCAQALASPE 2562
Query: 380 G---GSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 436
S A T+ + D P L + SA L L AG +P
Sbjct: 2563 SLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLT-PSAPSLTLEAGSIP---- 2617
Query: 437 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 496
G EA S T T P + P N + + P P
Sbjct: 2618 --------NGQEQEAPDS-AEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPL 2668
Query: 497 GA-KASNPFLPGGGPATGPSVTNPFQPAP-PATLTLNQLRLSPVPPVPGAPP-----TYI 549
A + S P + P A A T + SP P P PP +
Sbjct: 2669 EADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADV 2728
Query: 550 SPLGGGPGLPPMMPPGP 566
G G G P PPGP
Sbjct: 2729 EIRGQGTGRPG-QPPGP 2744
Score = 35.8 bits (81), Expect = 0.11
Identities = 41/146 (28%), Positives = 55/146 (37%), Gaps = 24/146 (16%)
Query: 445 RGSLAEAVGSPPPAATPTPT---------PPTRKTPESFLGPNAALVDLDSLVSRPGPTP 495
R L E +P P P P P ++ + + N L + RP P
Sbjct: 971 RRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRP---P 1027
Query: 496 PGAKASNPFLPGGGPATGP-----SVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYI- 549
PG + S PG P P S + P PA+ + L P+ P G+ P +
Sbjct: 1028 PGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLP 1087
Query: 550 SPLG--GGPGLPPM----MPPGPPAP 569
SPLG G PP + P PPAP
Sbjct: 1088 SPLGVLSGTSRPPTPTLSLKPTPPAP 1113
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 70.5 bits (171), Expect = 4e-12
Identities = 116/452 (25%), Positives = 156/452 (34%), Gaps = 75/452 (16%)
Query: 157 TATASSAAVGSGPP------PEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSCGPEDD 210
TA A SA + P PE A S EE +A A+++E PE
Sbjct: 897 TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEW- 955
Query: 211 AQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEE----SSLMDLADVFTA 266
A L + + ++ E+ E + + + + EE ++ + + T+
Sbjct: 956 AALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTS 1015
Query: 267 PA-----------PAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTP 315
PA PA P P AAAVPT + P P P +P A P
Sbjct: 1016 PAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVP 1073
Query: 316 ASGDPWRPAA-------PAGPSVD-PWGGTPAPAAGEGPTPDPWGSSDGGVPV----SGP 363
+P PAA P P+ P P A PTP+ S VP + P
Sbjct: 1074 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASP 1133
Query: 364 SASDPWTPAPAFSDPWGGSP--------AKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 415
+A+ P PAF P +P A P+ + + P E + F + L
Sbjct: 1134 AAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE 1193
Query: 416 TSGSSAGELELLAGEVPA----RSPGA-FDMSGVRGSLAEAVGSP-----PPAATPTPTP 465
S A + A V SP A S SLA AV +P P AA PT
Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEE 1253
Query: 466 PTRK-----TPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPF 520
PT TPE P A S+ + P P A SN P A P+ P
Sbjct: 1254 PTSSAAAVLTPEELSSPAA------SVPTPEEPASPAAAVSNLEEPASPAAAVPT---PE 1304
Query: 521 QPAPPATLTLNQLRLSPVPPVPGAPPTYISPL 552
A PA P P VP P + P+
Sbjct: 1305 VAAIPAASV-------PTPEVPAIPAAAVPPM 1329
Score = 60.1 bits (144), Expect = 5e-09
Identities = 87/341 (25%), Positives = 114/341 (33%), Gaps = 59/341 (17%)
Query: 271 PTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPS 330
P T P AAV + P VP +P A P +P PAA P
Sbjct: 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPP 1036
Query: 331 VDPWGGTPAPAAGEGPTPDPWGSSDGGVP---------VSGPSASDPWTPA---PAFSDP 378
+P +PA A PTP+ S VP + P+ +P +PA P +P
Sbjct: 1037 EEP--TSPAAAV---PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1091
Query: 379 WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
+ A P+ T+ P+E + A+PT A A VP A
Sbjct: 1092 TSPAAAVPTPEEPTSPAAAVPTPEEPAS---PAAAVPTPEEPASP----AAAVPTPEEPA 1144
Query: 439 FDMSGV-----RGSLAEAVGSPPPAATPTPTPPTRKTPESFLG----------------- 476
F V S A AV +P +A+P PT SF
Sbjct: 1145 FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT 1204
Query: 477 PNAALVDLDSLVSRPGPTPP-------GAKASNPFLPGGGPATGPSVTNPFQPAPPATLT 529
P A + L+ S P A SNP P A P++ P A A LT
Sbjct: 1205 PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA-AAVLT 1263
Query: 530 LNQLRLS----PVPPVPGAPPTYISPLGGGPGLPPMMPPGP 566
+L P P P +P +S L P P P P
Sbjct: 1264 PEELSSPAASVPTPEEPASPAAAVSNL-EEPASPAAAVPTP 1303
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 69.3 bits (168), Expect = 9e-12
Identities = 99/328 (30%), Positives = 116/328 (35%), Gaps = 76/328 (23%)
Query: 274 DPWGGPAPMAAAVPTAAP--TSDPWGGPPVPPAADPWGGPAPTPASGD----PWRPAAP- 326
DP G PAP A P+ P S+ W P + PA P+ PA + ASG W P
Sbjct: 590 DP-GVPAPQAPQAPSEVPQLVSETWASP-LFPAPRPF--PAQSSASGSFLLSGWDPEGRG 645
Query: 327 AGPSVDPWGGTPAPAAGEGPTPDPW---------GSSDGGVPVS---GPSASDPWTPAPA 374
AG ++ G PA GE T PW GSS G S GPS P P P
Sbjct: 646 AGETL---AGDPAEVLGERGTA-PWVEEEEEEEEGSSPGEDSSSLGGGPSRRGP-LPCPL 700
Query: 375 FSDPWGGSPAKPSTNGTTAAG-------GFDTEPDEFSDFDRLRTALPTSGSSAGELELL 427
S G P G AG G P++ S R G L L
Sbjct: 701 CSRE-GACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAER----------GSLADL 749
Query: 428 AGEVPARSPGAF--DMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLD 485
PA +P F + G G PP P P P P + P +A+
Sbjct: 750 PMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPG 809
Query: 486 SLVSRPGPTP--PGAKASNPF-----LPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPV 538
S +S PGP P G + PF PGGG A V P R P
Sbjct: 810 SGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRP--------------RAPPE 855
Query: 539 PPVPGAPPTYISPLGGGPGLPPMMPPGP 566
PP PGAP P P+ PGP
Sbjct: 856 PPDPGAPRP-------PPDPGPLPLPGP 876
Score = 56.2 bits (134), Expect = 8e-08
Identities = 99/381 (25%), Positives = 127/381 (33%), Gaps = 120/381 (31%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADP------------------W 308
P P P P+ P P A + P S P+ P ADP W
Sbjct: 451 PPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLW 510
Query: 309 -----------GGPAPTPASGDPWRPAAPAGP--------SVDPWGGTPAPAAGE----- 344
G PA PAS P A P+ P SV P +P+
Sbjct: 511 EKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIR 570
Query: 345 ----GPTPDP-----WGSSDGGVPV----SGPS-----ASDPWTPAPAFSDPWGGSPAKP 386
G P+P W D GVP PS S+ W +P F P PA+
Sbjct: 571 LEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWA-SPLFPAP-RPFPAQS 628
Query: 387 STNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRG 446
S +G+ G+D E G AGE LAG+ PA ++ G RG
Sbjct: 629 SASGSFLLSGWDPE-----------------GRGAGET--LAGD-PA------EVLGERG 662
Query: 447 SLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTP------PGAKA 500
+ P + E P L SR GP P GA +
Sbjct: 663 T--------------APWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACS 708
Query: 501 SNPFLPG---GGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVP--GAPPTYISPLGG- 554
P G G P++ P P ++L + L+ +P P APP ++ PL G
Sbjct: 709 CLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGA 768
Query: 555 ------GPGLPPMMPPGPPAP 569
G G PP PP PP P
Sbjct: 769 AAPQYPGRGPPPAPPPPPPPP 789
Score = 50.8 bits (120), Expect = 3e-06
Identities = 76/283 (26%), Positives = 92/283 (32%), Gaps = 54/283 (19%)
Query: 302 PPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAG--EGPTPDPWGSSDGGVP 359
PP PW P P + + W PA P G PAP P P SS G
Sbjct: 1047 PPETGPWRAPGPWEKTPESWGPA--------PTIGEPAPETSLERAPAPSAVVSSRNG-- 1096
Query: 360 VSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGS 419
G +A P PAP NGT G P E R A
Sbjct: 1097 --GETAPGPLGPAP--------------KNGTLEPGTERRAP-ETGGAPRAPGAGRLDLG 1139
Query: 420 SAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATP----------TPTPPTRK 469
S G + G P PG+ + G + PPP P P PP +
Sbjct: 1140 SGGRAPVGTGTAPGGGPGS-GVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRAR 1198
Query: 470 ---TPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ---PA 523
PE G + D+ +S G PP + P +P GP N Q
Sbjct: 1199 PEVAPEGEPGAPDSRAGGDTALSGDG-DPPKPERKGPEMPRLFLDLGPPQGNSEQIKARL 1257
Query: 524 PPATLTLNQLRLSPVP-PVPGAPPTYISPLG------GGPGLP 559
+L L L L+P P P P PP + G GG G P
Sbjct: 1258 SRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAP 1300
Score = 45.1 bits (105), Expect = 2e-04
Identities = 93/391 (23%), Positives = 118/391 (30%), Gaps = 87/391 (22%)
Query: 253 EESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP--------- 303
E SL DL A AP DP G AA P GPP P
Sbjct: 742 ERGSLADLPMAPPASAPPEFLDPLMG----------AAAPQYPGRGPPPAPPPPPPPPRA 791
Query: 304 AADPWGGPAPTPASGDPWRPAAPAGPSVDPWG-GTPAPAAGEGPTPDPWGSSDGGV--PV 360
ADP P P A P + GP G T P + EG P + + GV P
Sbjct: 792 PADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPR 851
Query: 361 SGPSASDPWTPAPAFSD---PWGGSPAKPS------------------------TNGTTA 393
+ P DP P P P G KP+ G TA
Sbjct: 852 APPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATA 911
Query: 394 -------AGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA------RSPGAFD 440
AG ++ +R T L +G A L L V R+PG +
Sbjct: 912 RETGPRKAGRGPGNREKVPGLNRDPTVL-GNGKQAPSLSLPVNGVTVLENGDQRAPGIEE 970
Query: 441 MSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKA 500
+ G+L TPP R+ G + + ++ G TPP K+
Sbjct: 971 KAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPP--KS 1028
Query: 501 SNPFLPGGG----------PATGP--------SVTNPFQPAPPATLTLNQLRLSPVPPVP 542
+ GG P TGP + PAP + L P
Sbjct: 1029 EDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAP--- 1085
Query: 543 GAPPTYISPLGGGPGLPPMMPPGPPAPNTNP 573
AP +S GG P + P P P
Sbjct: 1086 -APSAVVSSRNGGETAPGPLGPAPKNGTLEP 1115
Score = 44.7 bits (104), Expect = 2e-04
Identities = 75/335 (22%), Positives = 92/335 (27%), Gaps = 68/335 (20%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAP 326
P P P P + A P A P P G P P + GG GDP +P
Sbjct: 1175 PPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRA--GGDTALSGDGDPPKPERK 1232
Query: 327 AGPSVD--------PWGG------------------TPAPAAGEGPTPDPWGSSDGGVPV 360
GP + P G T P G GP PW +D G
Sbjct: 1233 -GPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGA-- 1289
Query: 361 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS 420
+G A P PA D G D + DE D +
Sbjct: 1290 AGGEAGGAGAPGPAEED------------------GEDEDEDEEEDEEAAAPGAAAGPRG 1331
Query: 421 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPT------------- 467
G V S A +RG L G+ P +
Sbjct: 1332 PGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLF 1391
Query: 468 -RKTPESFLGPNAALV-DLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVT----NPFQ 521
++TP + L A D D PTPP P G S P
Sbjct: 1392 DQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLL 1451
Query: 522 PAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 556
P P L ++ +SP PG P GP
Sbjct: 1452 PPPGPPLCFSRFSVSPALETPGPPARAPDARPAGP 1486
Score = 43.5 bits (101), Expect = 5e-04
Identities = 95/402 (23%), Positives = 114/402 (28%), Gaps = 97/402 (24%)
Query: 238 LQMAIEESKRETGGKEES---SLMDLADVFTAPAPAPTTDPWGGPAP----MAAAVPTAA 290
L+ E ETGG + +DL AP T P GGP A V
Sbjct: 1113 LEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTA-PGGGPGSGVDAKAGWVDNTR 1171
Query: 291 PTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPD- 349
P P PP P A PAP A + P P G T G+ P P+
Sbjct: 1172 PQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPER 1231
Query: 350 --------------PWGSSD----------------GGVPVSGPS-ASDPWTPAPAFSDP 378
P G+S+ P GP PW A A +
Sbjct: 1232 KGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAA- 1290
Query: 379 WGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
GG G G D + DE D + G V S A
Sbjct: 1291 -GGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADA 1349
Query: 439 FDMSGVRGSLAEAVGSPPP------------------------AATPTPTPPTRKTPESF 474
+RG L G+ P TPT + PE
Sbjct: 1350 DAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEG- 1408
Query: 475 LGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGG-PATGPSVTNPFQPAPPATLTLNQL 533
D D PTPP +P PG G P+ F+ A
Sbjct: 1409 --------DTDPSTPPAPPTPP-----HPATPGDGFPSNDSGFGGSFEWAED-------- 1447
Query: 534 RLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPP--APNTNP 573
P+ P PG PP S P L PGPP AP+ P
Sbjct: 1448 --FPLLPPPG-PPLCFSRFSVSPALE---TPGPPARAPDARP 1483
>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
sapiens]
Length = 245
Score = 69.3 bits (168), Expect = 9e-12
Identities = 91/307 (29%), Positives = 114/307 (37%), Gaps = 77/307 (25%)
Query: 255 SSLMDLADVFTAPAPAPT-----TDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWG 309
S LAD +PA T T P G P P P S+PW P P +
Sbjct: 2 SDEFSLADALPEHSPAKTSAVSNTKP-GQP-------PQGWPGSNPWNNPSAPSSVPSGL 53
Query: 310 GPAPTPASGDPWRPAAPAG--PSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASD 367
P+ TP++ P+ PA P G PSV P G P P P P+ P SGPS
Sbjct: 54 PPSATPSTV-PFGPA-PTGMYPSVPPTGPPPGP-------PAPF-------PPSGPSCPP 97
Query: 368 PWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 427
P P PA P+ G G + T F + R A PT ++AG L
Sbjct: 98 PGGPYPA-----------PTVPGPGPTGPYPTPNMPFPELPRPYGA-PTDPAAAGPLG-- 143
Query: 428 AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSL 487
P S + + G P P+ P P PP + P + P
Sbjct: 144 ----PWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGA--APPVPW------ 191
Query: 488 VSRPGPTPPGA---KASNPFLPGGGPATG--PSVTNPFQ-PAPPATLTLNQLRLSPVPPV 541
G PPGA A P G P G P+ +NPFQ P+ P S PP+
Sbjct: 192 ----GTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGP----------SGAPPM 237
Query: 542 PGAPPTY 548
PG P +Y
Sbjct: 238 PGGPHSY 244
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/188 (27%), Positives = 66/188 (35%), Gaps = 31/188 (16%)
Query: 402 DEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATP 461
DEFS D L P S+ + G+ P PG+ + + G PP +ATP
Sbjct: 3 DEFSLADALPEHSPAKTSAVSNTK--PGQPPQGWPGSNPWNNPSAPSSVPSGLPP-SATP 59
Query: 462 TPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQ 521
+ P P + PGP P + P GGP P+V P
Sbjct: 60 STVPFGP-------APTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGP 112
Query: 522 PAPPATLTLNQLRLSPVPPVP---GAP--PTYISPLG------GGPGLPPM----MPPGP 566
P T + P P +P GAP P PLG GP P M P
Sbjct: 113 TGPYPTPNM------PFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNM 166
Query: 567 PAPNTNPF 574
P P+ P+
Sbjct: 167 PYPSPGPY 174
Score = 40.0 bits (92), Expect = 0.006
Identities = 41/135 (30%), Positives = 49/135 (36%), Gaps = 23/135 (17%)
Query: 456 PPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPF----LPGGGPA 511
PP P P PP+ + GP A V PGPT P + PF P G P
Sbjct: 80 PPPGPPAPFPPSGPSCPPPGGPYPA-----PTVPGPGPTGPYPTPNMPFPELPRPYGAP- 133
Query: 512 TGPSVTNPFQP-----APPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPP-----M 561
T P+ P P + P + +P P P P P PG P
Sbjct: 134 TDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGT 193
Query: 562 MPP---GPPAPNTNP 573
+PP GPPAP P
Sbjct: 194 VPPGAWGPPAPYPAP 208
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 68.6 bits (166), Expect = 2e-11
Identities = 97/356 (27%), Positives = 122/356 (34%), Gaps = 69/356 (19%)
Query: 252 KEESSLMDLADVFTAPAPAPTTDPWGGPA--PMAAAVPTAAPTSDPWGGPPVPPAADPWG 309
KE SLM A++ AP PA + GPA P+A+A AAP ++P PP+
Sbjct: 311 KEYLSLM--AELGEAPVPA-SVGSTSGPATTPLASAPRPAAPANNP-----PPPSL---- 358
Query: 310 GPAPTPASGDPWRPAAPAG--PSVDPWGGTPA-PAAGEGPTPDPWGSSDGGVPVSGPSAS 366
T S PW + P+ P GG P P G P P S GG P
Sbjct: 359 --MSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHG-GHPMQH 415
Query: 367 DPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL 426
+P P P PW P P G G P D+ + P GS L
Sbjct: 416 NPNGPPP----PWMQPPPPPMNQGPHPPGHHGPPP-----MDQYLGSTPV-GSGVYRLHQ 465
Query: 427 LAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAAT-------------PTPTPPTRKTPES 473
G +P G S G PPP + P P PP+ S
Sbjct: 466 GKGMMPPPPMGMMPPPPPPPS-----GQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASS 520
Query: 474 FLGPNAALVDLDSLVSRPGPTPP------------------GAKASNPFLPGGGPATGPS 515
P + + G PP G P PG P P
Sbjct: 521 TPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPG 580
Query: 516 VTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLG-GGPGLPPM-MPPGPPAP 569
P P PP + + P PP P P +++ +G G G+PP MPP PP P
Sbjct: 581 APPPPPPPPPGSAGM-MYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPP 635
Score = 31.6 bits (70), Expect = 2.1
Identities = 28/93 (30%), Positives = 31/93 (33%), Gaps = 13/93 (13%)
Query: 266 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPP-----AADPWGGPAPTPASGDP 320
A A +P G M P P P PP PP A + P P P DP
Sbjct: 550 AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDP 609
Query: 321 WRPAAPAGPSV---DPWGGTPAPAAGEGPTPDP 350
G V P+G PAP P P P
Sbjct: 610 SNFVTMMGMGVAGMPPFGMPPAP-----PPPPP 637
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 67.4 bits (163), Expect = 3e-11
Identities = 86/331 (25%), Positives = 107/331 (32%), Gaps = 54/331 (16%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPT---AAPTSDPWGGPPVP--PAADPWGGPAPT-PASG 318
T PAPTT P PT +APT+ P P PA PAPT P
Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325
Query: 319 DPWRPAAPAGPSVDPWGGTP---APAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P P PA + +P TP AP A + P P P+ + P PAP
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---------TTPKEPAPTTPKEPAPTT 376
Query: 376 S-DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 434
+ +P +P +P+ T +A EP PT+ SA +
Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEP------------APTTTKSAPTTPKEPSPTTTK 424
Query: 435 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 494
P + + P P P P T K P P + P PT
Sbjct: 425 EPAP---TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPT 477
Query: 495 PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQL--------------RLSPVPP 540
P K + P P T P P P PA T +L +P P
Sbjct: 478 TP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 535
Query: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 571
AP T P P P P PAP T
Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566
Score = 65.9 bits (159), Expect = 1e-10
Identities = 81/325 (24%), Positives = 106/325 (32%), Gaps = 27/325 (8%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T PAPTT AP P T +P P PA PAPT P P
Sbjct: 243 TPKEPAPTTTK---SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 299
Query: 325 APAGPSVDPWGGT----PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-AFSDPW 379
PA + T PAP + PTP + P+ + P PAP A P
Sbjct: 300 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPA 357
Query: 380 GGSPAKPS-TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
+P +P+ T A EP + + T ++ ++ E + +P
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417
Query: 439 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT---- 494
+ + P P P P T K P P + +P PT
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPAPTTTKKPAPTTPKE 473
Query: 495 --PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVPPVPGAP--PTYI 549
P K + P P T P P P PA T +L +P P P P P
Sbjct: 474 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 533
Query: 550 SPLGGGPGL---PPMMPPGPPAPNT 571
+P P P P PAP T
Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTT 558
Score = 64.7 bits (156), Expect = 2e-10
Identities = 91/383 (23%), Positives = 131/383 (34%), Gaps = 38/383 (9%)
Query: 203 PSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLAD 262
PS P D + +L++++E + + + Q + + ++ T KE S+ +
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNK---QTSTDGKEKTTSAKETQSI----E 180
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAV---PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 319
+A APT+ P P A P +P P PA+ P PT
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240
Query: 320 PWRPAAPAGPSVDPWGGT---PAPAAGEGP---TPDPWGSSDGGVPVSGPSASDPWTPAP 373
P P PA + T PAP + P TP + P + S P TP
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP-- 298
Query: 374 AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA 433
+P +P KP+ TT T P E + A PT+ A
Sbjct: 299 --KEPAPTTPKKPAP--TTPKEPAPTTPKEPTPTTPKEPA-PTTKEPAPTTPKEPAPTAP 353
Query: 434 RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGP 493
+ P + + P P T P+P T K P +A + P P
Sbjct: 354 KKPAP---TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA-----PTTTKEPAP 405
Query: 494 TPPGAKASNPFLPGGGPATGPSVTNPFQPAP-----PATLTLNQLRLSPVPPVPGAPPTY 548
T + + P P P+ T P +PAP PA T + +P P AP T
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPAPTTT 463
Query: 549 ISPLGGGPGLPPMMPPGPPAPNT 571
P P P P AP T
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTT 486
Score = 59.7 bits (143), Expect = 7e-09
Identities = 80/316 (25%), Positives = 100/316 (31%), Gaps = 48/316 (15%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T PAPTT PAP P APT+ P P P TP + + P
Sbjct: 446 TPKEPAPTTPK--EPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 325 APAGPSVDPWGGTP---APAAGEGPTP----DPWGSSDGGVPVSGPSASDPWTPA-PAFS 376
P P+ TP AP E PTP +P ++ + P P TP PA +
Sbjct: 502 TPEKPAPT----TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 557
Query: 377 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 436
P +P P T G T P L+ PT+ EL +
Sbjct: 558 TPKEPAPTTPKETAPTTPKG--TAPTT------LKEPAPTTPKKPAPKELAPTTTKEPTS 609
Query: 437 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 496
D A +P A TP P TP+ + + P PT P
Sbjct: 610 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG---------TAPTTLKEPAPTTP 660
Query: 497 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 556
A P GP+ T +PAP P AP T P P
Sbjct: 661 KKPAPKELAPT--TTKGPTSTTSDKPAPTT-------------PKETAPTTPKEPAPTTP 705
Query: 557 GLPPMMPPGPPAPNTN 572
P P P P T+
Sbjct: 706 KKPAPTTPETPPPTTS 721
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 63/322 (19%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTA----APTSDPWGGPPVPPAADPWGGPAPTPASGDP 320
T PAPTT P PT APT+ P P P PTP + +
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529
Query: 321 WRPAAP--AGPSV--DPWGGTP---APAAGEGPTPDPWGSSDGGVP-------VSGPSAS 366
P P A P+ +P TP AP + P P + P + P+ +
Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589
Query: 367 DPWTPAP------AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGS 419
P PAP +P + KP+ TT G T P E + A T G+
Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 647
Query: 420 SAGELELLAGEVPAR-SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 478
+ L+ A P + +P + +G + P P TP T PT TP+
Sbjct: 648 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPT--TPKE----- 699
Query: 479 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL------TLNQ 532
P PT P K P P P T V+ P P T+ + +
Sbjct: 700 ------------PAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745
Query: 533 LRLSPVPPV-------PGAPPT 547
L P P PG P T
Sbjct: 746 LSAEPTPKALENSPKEPGVPTT 767
Score = 46.6 bits (109), Expect = 6e-05
Identities = 67/269 (24%), Positives = 92/269 (34%), Gaps = 25/269 (9%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T P PTT PAP AAP + P P P P P + P
Sbjct: 518 TPEEPTPTTPE--EPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 573
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS---------GPSASDPWTP-APA 374
P G + PAP + P P + P S P + P TP PA
Sbjct: 574 TPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632
Query: 375 FSDPWGGSPAKP-STNGTTAAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEV 431
+ P +P P T TT T P + + + T PTS +S E
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692
Query: 432 PARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF-LGPNAALVDLDSLVSR 490
+P + + +PPP + TP T K P + P+ + +L +
Sbjct: 693 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA---- 748
Query: 491 PGPTPPGAKASNPFLPGGGPATGPSVTNP 519
PTP A ++P PG P+ T P
Sbjct: 749 -EPTPK-ALENSPKEPGVPTTKTPAATKP 775
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 67.4 bits (163), Expect = 3e-11
Identities = 86/331 (25%), Positives = 107/331 (32%), Gaps = 54/331 (16%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPT---AAPTSDPWGGPPVP--PAADPWGGPAPT-PASG 318
T PAPTT P PT +APT+ P P PA PAPT P
Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366
Query: 319 DPWRPAAPAGPSVDPWGGTP---APAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P P PA + +P TP AP A + P P P+ + P PAP
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---------TTPKEPAPTTPKEPAPTT 417
Query: 376 S-DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 434
+ +P +P +P+ T +A EP PT+ SA +
Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEP------------APTTTKSAPTTPKEPSPTTTK 465
Query: 435 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 494
P + + P P P P T K P P + P PT
Sbjct: 466 EPAP---TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPT 518
Query: 495 PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQL--------------RLSPVPP 540
P K + P P T P P P PA T +L +P P
Sbjct: 519 TP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 576
Query: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 571
AP T P P P P PAP T
Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607
Score = 65.9 bits (159), Expect = 1e-10
Identities = 81/325 (24%), Positives = 106/325 (32%), Gaps = 27/325 (8%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T PAPTT AP P T +P P PA PAPT P P
Sbjct: 284 TPKEPAPTTTK---SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 340
Query: 325 APAGPSVDPWGGT----PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-AFSDPW 379
PA + T PAP + PTP + P+ + P PAP A P
Sbjct: 341 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPA 398
Query: 380 GGSPAKPS-TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
+P +P+ T A EP + + T ++ ++ E + +P
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458
Query: 439 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT---- 494
+ + P P P P T K P P + +P PT
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPAPTTTKKPAPTTPKE 514
Query: 495 --PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVPPVPGAP--PTYI 549
P K + P P T P P P PA T +L +P P P P P
Sbjct: 515 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 574
Query: 550 SPLGGGPGL---PPMMPPGPPAPNT 571
+P P P P PAP T
Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTT 599
Score = 64.7 bits (156), Expect = 2e-10
Identities = 91/383 (23%), Positives = 131/383 (34%), Gaps = 38/383 (9%)
Query: 203 PSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLAD 262
PS P D + +L++++E + + + Q + + ++ T KE S+ +
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNK---QTSTDGKEKTTSAKETQSI----E 221
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAV---PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 319
+A APT+ P P A P +P P PA+ P PT
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281
Query: 320 PWRPAAPAGPSVDPWGGT---PAPAAGEGP---TPDPWGSSDGGVPVSGPSASDPWTPAP 373
P P PA + T PAP + P TP + P + S P TP
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP-- 339
Query: 374 AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA 433
+P +P KP+ TT T P E + A PT+ A
Sbjct: 340 --KEPAPTTPKKPAP--TTPKEPAPTTPKEPTPTTPKEPA-PTTKEPAPTTPKEPAPTAP 394
Query: 434 RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGP 493
+ P + + P P T P+P T K P +A + P P
Sbjct: 395 KKPAP---TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA-----PTTTKEPAP 446
Query: 494 TPPGAKASNPFLPGGGPATGPSVTNPFQPAP-----PATLTLNQLRLSPVPPVPGAPPTY 548
T + + P P P+ T P +PAP PA T + +P P AP T
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPAPTTT 504
Query: 549 ISPLGGGPGLPPMMPPGPPAPNT 571
P P P P AP T
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTT 527
Score = 59.7 bits (143), Expect = 7e-09
Identities = 80/316 (25%), Positives = 100/316 (31%), Gaps = 48/316 (15%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T PAPTT PAP P APT+ P P P TP + + P
Sbjct: 487 TPKEPAPTTPK--EPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 325 APAGPSVDPWGGTP---APAAGEGPTP----DPWGSSDGGVPVSGPSASDPWTPA-PAFS 376
P P+ TP AP E PTP +P ++ + P P TP PA +
Sbjct: 543 TPEKPAPT----TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 598
Query: 377 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 436
P +P P T G T P L+ PT+ EL +
Sbjct: 599 TPKEPAPTTPKETAPTTPKG--TAPTT------LKEPAPTTPKKPAPKELAPTTTKEPTS 650
Query: 437 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 496
D A +P A TP P TP+ + + P PT P
Sbjct: 651 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG---------TAPTTLKEPAPTTP 701
Query: 497 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 556
A P GP+ T +PAP P AP T P P
Sbjct: 702 KKPAPKELAPT--TTKGPTSTTSDKPAPTT-------------PKETAPTTPKEPAPTTP 746
Query: 557 GLPPMMPPGPPAPNTN 572
P P P P T+
Sbjct: 747 KKPAPTTPETPPPTTS 762
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 63/322 (19%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTA----APTSDPWGGPPVPPAADPWGGPAPTPASGDP 320
T PAPTT P PT APT+ P P P PTP + +
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570
Query: 321 WRPAAP--AGPSV--DPWGGTP---APAAGEGPTPDPWGSSDGGVP-------VSGPSAS 366
P P A P+ +P TP AP + P P + P + P+ +
Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630
Query: 367 DPWTPAP------AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGS 419
P PAP +P + KP+ TT G T P E + A T G+
Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 688
Query: 420 SAGELELLAGEVPAR-SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 478
+ L+ A P + +P + +G + P P TP T PT TP+
Sbjct: 689 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPT--TPKE----- 740
Query: 479 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL------TLNQ 532
P PT P K P P P T V+ P P T+ + +
Sbjct: 741 ------------PAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786
Query: 533 LRLSPVPPV-------PGAPPT 547
L P P PG P T
Sbjct: 787 LSAEPTPKALENSPKEPGVPTT 808
Score = 46.6 bits (109), Expect = 6e-05
Identities = 67/269 (24%), Positives = 92/269 (34%), Gaps = 25/269 (9%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T P PTT PAP AAP + P P P P P + P
Sbjct: 559 TPEEPTPTTPE--EPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 614
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS---------GPSASDPWTP-APA 374
P G + PAP + P P + P S P + P TP PA
Sbjct: 615 TPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673
Query: 375 FSDPWGGSPAKP-STNGTTAAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEV 431
+ P +P P T TT T P + + + T PTS +S E
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733
Query: 432 PARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF-LGPNAALVDLDSLVSR 490
+P + + +PPP + TP T K P + P+ + +L +
Sbjct: 734 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA---- 789
Query: 491 PGPTPPGAKASNPFLPGGGPATGPSVTNP 519
PTP A ++P PG P+ T P
Sbjct: 790 -EPTPK-ALENSPKEPGVPTTKTPAATKP 816
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 67.4 bits (163), Expect = 3e-11
Identities = 86/331 (25%), Positives = 107/331 (32%), Gaps = 54/331 (16%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPT---AAPTSDPWGGPPVP--PAADPWGGPAPT-PASG 318
T PAPTT P PT +APT+ P P PA PAPT P
Sbjct: 359 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418
Query: 319 DPWRPAAPAGPSVDPWGGTP---APAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P P PA + +P TP AP A + P P P+ + P PAP
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---------TTPKEPAPTTPKEPAPTT 469
Query: 376 S-DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 434
+ +P +P +P+ T +A EP PT+ SA +
Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEP------------APTTTKSAPTTPKEPSPTTTK 517
Query: 435 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 494
P + + P P P P T K P P + P PT
Sbjct: 518 EPAP---TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPT 570
Query: 495 PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQL--------------RLSPVPP 540
P K + P P T P P P PA T +L +P P
Sbjct: 571 TP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 628
Query: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 571
AP T P P P P PAP T
Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659
Score = 65.9 bits (159), Expect = 1e-10
Identities = 81/325 (24%), Positives = 106/325 (32%), Gaps = 27/325 (8%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T PAPTT AP P T +P P PA PAPT P P
Sbjct: 336 TPKEPAPTTTK---SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 392
Query: 325 APAGPSVDPWGGT----PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-AFSDPW 379
PA + T PAP + PTP + P+ + P PAP A P
Sbjct: 393 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
Query: 380 GGSPAKPS-TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
+P +P+ T A EP + + T ++ ++ E + +P
Sbjct: 451 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510
Query: 439 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT---- 494
+ + P P P P T K P P + +P PT
Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPAPTTTKKPAPTTPKE 566
Query: 495 --PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVPPVPGAP--PTYI 549
P K + P P T P P P PA T +L +P P P P P
Sbjct: 567 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 626
Query: 550 SPLGGGPGL---PPMMPPGPPAPNT 571
+P P P P PAP T
Sbjct: 627 TPKAAAPNTPKEPAPTTPKEPAPTT 651
Score = 64.7 bits (156), Expect = 2e-10
Identities = 91/383 (23%), Positives = 131/383 (34%), Gaps = 38/383 (9%)
Query: 203 PSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLAD 262
PS P D + +L++++E + + + Q + + ++ T KE S+ +
Sbjct: 221 PSLPPNSDTSKETSLTVNKETTVETKETTTTNK---QTSTDGKEKTTSAKETQSI----E 273
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAV---PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 319
+A APT+ P P A P +P P PA+ P PT
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333
Query: 320 PWRPAAPAGPSVDPWGGT---PAPAAGEGP---TPDPWGSSDGGVPVSGPSASDPWTPAP 373
P P PA + T PAP + P TP + P + S P TP
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP-- 391
Query: 374 AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA 433
+P +P KP+ TT T P E + A PT+ A
Sbjct: 392 --KEPAPTTPKKPAP--TTPKEPAPTTPKEPTPTTPKEPA-PTTKEPAPTTPKEPAPTAP 446
Query: 434 RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGP 493
+ P + + P P T P+P T K P +A + P P
Sbjct: 447 KKPAP---TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA-----PTTTKEPAP 498
Query: 494 TPPGAKASNPFLPGGGPATGPSVTNPFQPAP-----PATLTLNQLRLSPVPPVPGAPPTY 548
T + + P P P+ T P +PAP PA T + +P P AP T
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPAPTTT 556
Query: 549 ISPLGGGPGLPPMMPPGPPAPNT 571
P P P P AP T
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTT 579
Score = 59.7 bits (143), Expect = 7e-09
Identities = 80/316 (25%), Positives = 100/316 (31%), Gaps = 48/316 (15%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T PAPTT PAP P APT+ P P P TP + + P
Sbjct: 539 TPKEPAPTTPK--EPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 594
Query: 325 APAGPSVDPWGGTP---APAAGEGPTP----DPWGSSDGGVPVSGPSASDPWTPA-PAFS 376
P P+ TP AP E PTP +P ++ + P P TP PA +
Sbjct: 595 TPEKPAPT----TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 650
Query: 377 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 436
P +P P T G T P L+ PT+ EL +
Sbjct: 651 TPKEPAPTTPKETAPTTPKG--TAPTT------LKEPAPTTPKKPAPKELAPTTTKEPTS 702
Query: 437 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 496
D A +P A TP P TP+ + + P PT P
Sbjct: 703 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG---------TAPTTLKEPAPTTP 753
Query: 497 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 556
A P GP+ T +PAP P AP T P P
Sbjct: 754 KKPAPKELAPT--TTKGPTSTTSDKPAPTT-------------PKETAPTTPKEPAPTTP 798
Query: 557 GLPPMMPPGPPAPNTN 572
P P P P T+
Sbjct: 799 KKPAPTTPETPPPTTS 814
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 63/322 (19%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTA----APTSDPWGGPPVPPAADPWGGPAPTPASGDP 320
T PAPTT P PT APT+ P P P PTP + +
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 321 WRPAAP--AGPSV--DPWGGTP---APAAGEGPTPDPWGSSDGGVP-------VSGPSAS 366
P P A P+ +P TP AP + P P + P + P+ +
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Query: 367 DPWTPAP------AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGS 419
P PAP +P + KP+ TT G T P E + A T G+
Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 740
Query: 420 SAGELELLAGEVPAR-SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 478
+ L+ A P + +P + +G + P P TP T PT TP+
Sbjct: 741 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPT--TPKE----- 792
Query: 479 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL------TLNQ 532
P PT P K P P P T V+ P P T+ + +
Sbjct: 793 ------------PAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838
Query: 533 LRLSPVPPV-------PGAPPT 547
L P P PG P T
Sbjct: 839 LSAEPTPKALENSPKEPGVPTT 860
Score = 46.6 bits (109), Expect = 6e-05
Identities = 67/269 (24%), Positives = 92/269 (34%), Gaps = 25/269 (9%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T P PTT PAP AAP + P P P P P + P
Sbjct: 611 TPEEPTPTTPE--EPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 666
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS---------GPSASDPWTP-APA 374
P G + PAP + P P + P S P + P TP PA
Sbjct: 667 TPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725
Query: 375 FSDPWGGSPAKP-STNGTTAAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEV 431
+ P +P P T TT T P + + + T PTS +S E
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785
Query: 432 PARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF-LGPNAALVDLDSLVSR 490
+P + + +PPP + TP T K P + P+ + +L +
Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA---- 841
Query: 491 PGPTPPGAKASNPFLPGGGPATGPSVTNP 519
PTP A ++P PG P+ T P
Sbjct: 842 -EPTPK-ALENSPKEPGVPTTKTPAATKP 868
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 67.4 bits (163), Expect = 3e-11
Identities = 86/331 (25%), Positives = 107/331 (32%), Gaps = 54/331 (16%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPT---AAPTSDPWGGPPVP--PAADPWGGPAPT-PASG 318
T PAPTT P PT +APT+ P P PA PAPT P
Sbjct: 400 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459
Query: 319 DPWRPAAPAGPSVDPWGGTP---APAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAF 375
P P PA + +P TP AP A + P P P+ + P PAP
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---------TTPKEPAPTTPKEPAPTT 510
Query: 376 S-DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPAR 434
+ +P +P +P+ T +A EP PT+ SA +
Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEP------------APTTTKSAPTTPKEPSPTTTK 558
Query: 435 SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT 494
P + + P P P P T K P P + P PT
Sbjct: 559 EPAP---TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPT 611
Query: 495 PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQL--------------RLSPVPP 540
P K + P P T P P P PA T +L +P P
Sbjct: 612 TP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 669
Query: 541 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNT 571
AP T P P P P PAP T
Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700
Score = 65.9 bits (159), Expect = 1e-10
Identities = 81/325 (24%), Positives = 106/325 (32%), Gaps = 27/325 (8%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T PAPTT AP P T +P P PA PAPT P P
Sbjct: 377 TPKEPAPTTTK---SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 433
Query: 325 APAGPSVDPWGGT----PAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAP-AFSDPW 379
PA + T PAP + PTP + P+ + P PAP A P
Sbjct: 434 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPA 491
Query: 380 GGSPAKPS-TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGA 438
+P +P+ T A EP + + T ++ ++ E + +P
Sbjct: 492 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551
Query: 439 FDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPT---- 494
+ + P P P P T K P P + +P PT
Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPAPTTTKKPAPTTPKE 607
Query: 495 --PPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLR-LSPVPPVPGAP--PTYI 549
P K + P P T P P P PA T +L +P P P P P
Sbjct: 608 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 667
Query: 550 SPLGGGPGL---PPMMPPGPPAPNT 571
+P P P P PAP T
Sbjct: 668 TPKAAAPNTPKEPAPTTPKEPAPTT 692
Score = 64.7 bits (156), Expect = 2e-10
Identities = 91/383 (23%), Positives = 131/383 (34%), Gaps = 38/383 (9%)
Query: 203 PSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLAD 262
PS P D + +L++++E + + + Q + + ++ T KE S+ +
Sbjct: 262 PSLPPNSDTSKETSLTVNKETTVETKETTTTNK---QTSTDGKEKTTSAKETQSI----E 314
Query: 263 VFTAPAPAPTTDPWGGPAPMAAAV---PTAAPTSDPWGGPPVPPAADPWGGPAPTPASGD 319
+A APT+ P P A P +P P PA+ P PT
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374
Query: 320 PWRPAAPAGPSVDPWGGT---PAPAAGEGP---TPDPWGSSDGGVPVSGPSASDPWTPAP 373
P P PA + T PAP + P TP + P + S P TP
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP-- 432
Query: 374 AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPA 433
+P +P KP+ TT T P E + A PT+ A
Sbjct: 433 --KEPAPTTPKKPAP--TTPKEPAPTTPKEPTPTTPKEPA-PTTKEPAPTTPKEPAPTAP 487
Query: 434 RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGP 493
+ P + + P P T P+P T K P +A + P P
Sbjct: 488 KKPAP---TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA-----PTTTKEPAP 539
Query: 494 TPPGAKASNPFLPGGGPATGPSVTNPFQPAP-----PATLTLNQLRLSPVPPVPGAPPTY 548
T + + P P P+ T P +PAP PA T + +P P AP T
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPAPTTT 597
Query: 549 ISPLGGGPGLPPMMPPGPPAPNT 571
P P P P AP T
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTT 620
Score = 59.7 bits (143), Expect = 7e-09
Identities = 80/316 (25%), Positives = 100/316 (31%), Gaps = 48/316 (15%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T PAPTT PAP P APT+ P P P TP + + P
Sbjct: 580 TPKEPAPTTPK--EPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 635
Query: 325 APAGPSVDPWGGTP---APAAGEGPTP----DPWGSSDGGVPVSGPSASDPWTPA-PAFS 376
P P+ TP AP E PTP +P ++ + P P TP PA +
Sbjct: 636 TPEKPAPT----TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 691
Query: 377 DPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSP 436
P +P P T G T P L+ PT+ EL +
Sbjct: 692 TPKEPAPTTPKETAPTTPKG--TAPTT------LKEPAPTTPKKPAPKELAPTTTKEPTS 743
Query: 437 GAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPP 496
D A +P A TP P TP+ + + P PT P
Sbjct: 744 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG---------TAPTTLKEPAPTTP 794
Query: 497 GAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGP 556
A P GP+ T +PAP P AP T P P
Sbjct: 795 KKPAPKELAPT--TTKGPTSTTSDKPAPTT-------------PKETAPTTPKEPAPTTP 839
Query: 557 GLPPMMPPGPPAPNTN 572
P P P P T+
Sbjct: 840 KKPAPTTPETPPPTTS 855
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 63/322 (19%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTA----APTSDPWGGPPVPPAADPWGGPAPTPASGDP 320
T PAPTT P PT APT+ P P P PTP + +
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 321 WRPAAP--AGPSV--DPWGGTP---APAAGEGPTPDPWGSSDGGVP-------VSGPSAS 366
P P A P+ +P TP AP + P P + P + P+ +
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Query: 367 DPWTPAP------AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPT-SGS 419
P PAP +P + KP+ TT G T P E + A T G+
Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 781
Query: 420 SAGELELLAGEVPAR-SPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPN 478
+ L+ A P + +P + +G + P P TP T PT TP+
Sbjct: 782 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPT--TPKE----- 833
Query: 479 AALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATL------TLNQ 532
P PT P K P P P T V+ P P T+ + +
Sbjct: 834 ------------PAPTTP--KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879
Query: 533 LRLSPVPPV-------PGAPPT 547
L P P PG P T
Sbjct: 880 LSAEPTPKALENSPKEPGVPTT 901
Score = 46.6 bits (109), Expect = 6e-05
Identities = 67/269 (24%), Positives = 92/269 (34%), Gaps = 25/269 (9%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPA 324
T P PTT PAP AAP + P P P P P + P
Sbjct: 652 TPEEPTPTTPE--EPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 707
Query: 325 APAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVS---------GPSASDPWTP-APA 374
P G + PAP + P P + P S P + P TP PA
Sbjct: 708 TPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766
Query: 375 FSDPWGGSPAKP-STNGTTAAGGFDTEPDEFSDFDRLRTAL--PTSGSSAGELELLAGEV 431
+ P +P P T TT T P + + + T PTS +S E
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826
Query: 432 PARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESF-LGPNAALVDLDSLVSR 490
+P + + +PPP + TP T K P + P+ + +L +
Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA---- 882
Query: 491 PGPTPPGAKASNPFLPGGGPATGPSVTNP 519
PTP A ++P PG P+ T P
Sbjct: 883 -EPTPK-ALENSPKEPGVPTTKTPAATKP 909
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 67.4 bits (163), Expect = 3e-11
Identities = 84/308 (27%), Positives = 100/308 (32%), Gaps = 45/308 (14%)
Query: 275 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPW 334
P GG P P P P G P P G P P GD R +P P P
Sbjct: 62 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR--SPRSPPGKPQ 119
Query: 335 GGTPAPAAG---EGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGT 391
G P P G +GP P P G G P G P P G P P G
Sbjct: 120 G--PPPQGGNQPQGPPPPP-GKPQGPPPQGGNKPQGPPPP---------GKPQGPPPQGD 167
Query: 392 TAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEA 451
+ + P + + P G+ + P PG +G
Sbjct: 168 NKSRSSRSPPG------KPQGPPPQGGNQP--------QGPPPPPGKPQGPPPQGG--NK 211
Query: 452 VGSPPPAATPTPTPPT--RKTPESFLGPNAALVDLDSLVSRP-GPTPPGAKASNPFLPGG 508
PPP P PP K+ + P ++P GP PP K P GG
Sbjct: 212 PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 271
Query: 509 GPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGG----GPGLPPMMPP 564
GP Q PP + ++ SP P P PP P GG GP PP P
Sbjct: 272 NKPQGPPPPGKPQGPPPQGGSKSRSSRSP-PGKPQGPP----PQGGNQPQGPPPPPGKPQ 326
Query: 565 GPPAPNTN 572
GPP N
Sbjct: 327 GPPPQGGN 334
Score = 63.2 bits (152), Expect = 6e-10
Identities = 82/318 (25%), Positives = 96/318 (30%), Gaps = 59/318 (18%)
Query: 275 PWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWR------PAAPAG 328
P GG P P P P G P P G P P GD P P G
Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182
Query: 329 PSVD----PWGGTPAPAAGEGPTPD----PWGSSDGGVPVSGPSASD------------P 368
P P G P P +GP P P G G P P D P
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242
Query: 369 WTPAP-AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELL 427
P P + P G P G GG +P + + P GS +
Sbjct: 243 QGPPPQGGNQPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGGSKSRS---- 296
Query: 428 AGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSL 487
+RSP + G PPP P PP G N
Sbjct: 297 -----SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ--------GGNKP------- 336
Query: 488 VSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPT 547
GP PPG P P GG + + + P +P P N + P PP G P
Sbjct: 337 ---QGPPPPGKPQGPP--PQGGSKSRSARSPPGKPQGPPQQEGNNPQ-GPPPPAGGNPQQ 390
Query: 548 YISPLGGGPGLPPMMPPG 565
+P G P PP P G
Sbjct: 391 PQAPPAGQPQGPPRPPQG 408
Score = 60.5 bits (145), Expect = 4e-09
Identities = 73/279 (26%), Positives = 80/279 (28%), Gaps = 50/279 (17%)
Query: 302 PPAADPWGGPAPTPASGDPWRPAAPAGPSVD----PWGGTPAPAAGEGPTPDPWGSSDGG 357
P A P GG P G P P P GP P G P P +GP P G
Sbjct: 36 PQGAPPQGGNKP---QGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92
Query: 358 VPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTS 417
P P P G P P G G P + P
Sbjct: 93 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-------PQGPPPQ 145
Query: 418 GSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGP 477
G + + G P PG +G PP P P P+
Sbjct: 146 GGNKPQ-----GPPP---PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ----- 192
Query: 478 NAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP 537
GP PP K P GG GP Q PP +Q SP
Sbjct: 193 --------------GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238
Query: 538 VPPVPGAPPTYISPLGG----GPGLPPMMPPGPPAPNTN 572
P P PP P GG GP PP P GPP N
Sbjct: 239 -PGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGN 272
Score = 41.2 bits (95), Expect = 0.003
Identities = 42/163 (25%), Positives = 52/163 (31%), Gaps = 24/163 (14%)
Query: 244 ESKRETGGKEESSLMDLADVFTAPAPAPTTD----PWGGPAPMAAAVPTAAPTSDPWGG- 298
+S R GK + + P P P P GG P P P GG
Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 292
Query: 299 --------PPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDP 350
P P P GG P P +P P + G P P +GP P
Sbjct: 293 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352
Query: 351 WGSSDG-----GVPVSGP--SASDPWTPAPAFSDPWGGSPAKP 386
S G P P ++P P P P GG+P +P
Sbjct: 353 GSKSRSARSPPGKPQGPPQQEGNNPQGPPP----PAGGNPQQP 391
Score = 39.3 bits (90), Expect = 0.010
Identities = 34/118 (28%), Positives = 38/118 (32%), Gaps = 21/118 (17%)
Query: 269 PAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAG 328
P P GP P P P P G P PP P GG A P +P P
Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPP---PQGGSKSRSARSPPGKPQGPPQ 371
Query: 329 PSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKP 386
+ G P PA G P P A P P P GG P++P
Sbjct: 372 QEGNNPQGPPPPAGGNPQQP------------QAPPAGQPQGPP---RPPQGGRPSRP 414
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 67.0 bits (162), Expect = 4e-11
Identities = 79/286 (27%), Positives = 105/286 (36%), Gaps = 31/286 (10%)
Query: 297 GGPPVPPAADPWGGPAPTPASGDPWRPAAPAG----PSVDPWGGTPAPAAGEGPTPD-PW 351
G PVP + GPA TP + P RPAAPA PS+ + P GP+ P+
Sbjct: 321 GEAPVPASVGSTSGPATTPLASAP-RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
Query: 352 GSSDGGVPVSGPSASDPWT---PAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFD 408
GG P G P + P P+ + GG P + + NG P +
Sbjct: 380 HGMHGGGP--GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPW-MQPPPPPMNQGP 436
Query: 409 RLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAAT--PTPTPP 466
P ++ G P S G + + +G + PPP P P PP
Sbjct: 437 H-----PPGHHGPPPMDQYLGSTPVGS-GVYRLHQGKGMMP-----PPPMGMMPPPPPPP 485
Query: 467 TRKTPESFLGPNAALVDLDSLVSRPGPTPP--GAKASNPFLPGGGPATGPSVTNPFQPAP 524
+ + P GP L +P P PP + AS+ LP T + + P
Sbjct: 486 SGQPPPPPSGP---LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIP 542
Query: 525 PATLTLNQLRLSP-VPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 569
P SP P + G P P G P LPP PP PP P
Sbjct: 543 PWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP 588
Score = 45.1 bits (105), Expect = 2e-04
Identities = 92/356 (25%), Positives = 110/356 (30%), Gaps = 108/356 (30%)
Query: 252 KEESSLMDLADVFTAPAPAPTTDPWGGPA--PMAAAVPTAAPTSDP-------------- 295
KE SLM A++ AP PA + GPA P+A+A AAP ++P
Sbjct: 311 KEYLSLM--AELGEAPVPA-SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPP 367
Query: 296 W---------------GGPPVPPAADPWGGPAPTPA-----SGDPWRPAAPAGPSVDPWG 335
W GG P P P P P P+ G P + P GP PW
Sbjct: 368 WMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQ-HNPNGPP-PPWM 425
Query: 336 GTPAPAAGEGP------TPDPWGSSDGGVPV----------SGPSASDPWTPAPAFSDPW 379
P P +GP P P G PV G P P P
Sbjct: 426 QPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
Query: 380 GGSPAKPSTNGTTAAGGFDTE---PDEFSDFDRLRTALP------TSGSSAGELELLAGE 430
G P P + + P S T LP T+ +SAG G
Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAG-----TGS 540
Query: 431 VP---------ARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAAL 481
+P A SPGA M G + G PP P PP
Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP--------------- 585
Query: 482 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSP 537
P PP A P GG GPS + P P TL Q + P
Sbjct: 586 -----------PPPPPGSAGMMIPPRGG--DGPSHESEDFPRPLVTLPGRQPQQRP 628
Score = 32.7 bits (73), Expect = 0.93
Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 12/98 (12%)
Query: 265 TAPAPAPTTDPWGGPAPMAAAVPTAA-----PTS---DPWGGPPVPPAADPWGGPAPTPA 316
T A + PW AAA P A PT P PP+PP A P P P +
Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS 592
Query: 317 SGDPWRPAAPAGPSVDPWGGTPAPAA---GEGPTPDPW 351
+G P GPS + P P G P PW
Sbjct: 593 AGMMIPPRGGDGPSHES-EDFPRPLVTLPGRQPQQRPW 629
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 66.6 bits (161), Expect = 6e-11
Identities = 88/346 (25%), Positives = 110/346 (31%), Gaps = 67/346 (19%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTS--DPWGGPPVPPAADPWGGPAPTPASG------ 318
P P P+ P P M P +P S G P PP+A G P PT G
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA---GHPIPTQGPGGYPQDN 68
Query: 319 -----DPWRPAAPAGPSVDP-------WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSAS 366
P G S DP G AG GP P P G P +
Sbjct: 69 MHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128
Query: 367 DPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL 426
+P PA S P G G G +P +R T + ++
Sbjct: 129 HASSPVPA-SGPSSGPQMSSGPGGAPLDG---ADPQALGQQNRGPTPFNQNQLHQLRAQI 184
Query: 427 LAGEVPARS-----------PGAFDMSGVRGSL-------AEAVG-----SPPPAATPTP 463
+A ++ AR G M G++ + A G P P P P
Sbjct: 185 MAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGP 244
Query: 464 TPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPA 523
PP P GPN P P P G P P GGP P P A
Sbjct: 245 APPNYSRPHGMGGPN-----------MPPPGPSGVPPGMPGQPPGGPPK-PWPEGPMANA 292
Query: 524 PPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 569
T T +L +PP P P+ +P P P+MPP +P
Sbjct: 293 AAPTSTPQKL----IPPQPTGRPS-PAPPAVPPAASPVMPPQTQSP 333
Score = 52.4 bits (124), Expect = 1e-06
Identities = 72/269 (26%), Positives = 92/269 (34%), Gaps = 40/269 (14%)
Query: 333 PWGGTPAPAAGEGPTPDP---WGSSDGGVPVSGPS--ASDPWTPAPAFSDPWGGSPAKPS 387
P GGTP P GP P P G S G P S S P P+ P G P
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQ 66
Query: 388 TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGS 447
N ++ ++ D + G +G AG P SP G
Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGG---HAGMGPPPSPMDQHSQGYPSP 123
Query: 448 L--AEAVGSPPPAATPTPTPPTRKTP--------------ESFLGPN----------AAL 481
L +E SP PA+ P+ P P + GP A
Sbjct: 124 LGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQ 183
Query: 482 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP-P 540
+ +++R P P + + + G P G P P P + T P P P
Sbjct: 184 IMAYKMLARGQPLPDHLQMA---VQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP 240
Query: 541 VPG-APPTYISPLG-GGPGLPPMMPPGPP 567
PG APP Y P G GGP +PP P G P
Sbjct: 241 GPGPAPPNYSRPHGMGGPNMPPPGPSGVP 269
Score = 51.2 bits (121), Expect = 3e-06
Identities = 70/261 (26%), Positives = 88/261 (33%), Gaps = 54/261 (20%)
Query: 161 SSAAVGSGPPP----EAEQAWPQSSGEEELQLQLALAMSKEEADQP---PSCGPEDDAQL 213
S G GPPP + Q +P G E A Q P P D A
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159
Query: 214 QLALSLSR--------EEHDKEERIR------RGDDL--RLQMAIEESKRETGGKEESSL 257
Q +R + H +I RG L LQMA++ + G +++
Sbjct: 160 QALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPT 219
Query: 258 MDLADVF-TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPA 316
+ V T P P P P GP P P GGP +PP P P+
Sbjct: 220 LPPPSVSATGPGPGPGPGPGPGPGP----APPNYSRPHGMGGPNMPP---------PGPS 266
Query: 317 SGDPWRPAAPAGPSVDPW-GGTPAPAAGEGPT------PDPWGSSDGGVPVSGPSAS--- 366
P P P G PW G A AA T P P G P P+AS
Sbjct: 267 GVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM 326
Query: 367 DPWTPAPAFSDPWGGSPAKPS 387
P T +P G PA+P+
Sbjct: 327 PPQTQSP-------GQPAQPA 340
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 66.6 bits (161), Expect = 6e-11
Identities = 88/346 (25%), Positives = 110/346 (31%), Gaps = 67/346 (19%)
Query: 267 PAPAPTTDPWGGPAPMAAAVPTAAPTS--DPWGGPPVPPAADPWGGPAPTPASG------ 318
P P P+ P P M P +P S G P PP+A G P PT G
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA---GHPIPTQGPGGYPQDN 68
Query: 319 -----DPWRPAAPAGPSVDP-------WGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSAS 366
P G S DP G AG GP P P G P +
Sbjct: 69 MHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128
Query: 367 DPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELEL 426
+P PA S P G G G +P +R T + ++
Sbjct: 129 HASSPVPA-SGPSSGPQMSSGPGGAPLDG---ADPQALGQQNRGPTPFNQNQLHQLRAQI 184
Query: 427 LAGEVPARS-----------PGAFDMSGVRGSL-------AEAVG-----SPPPAATPTP 463
+A ++ AR G M G++ + A G P P P P
Sbjct: 185 MAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGP 244
Query: 464 TPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPA 523
PP P GPN P P P G P P GGP P P A
Sbjct: 245 APPNYSRPHGMGGPN-----------MPPPGPSGVPPGMPGQPPGGPPK-PWPEGPMANA 292
Query: 524 PPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAP 569
T T +L +PP P P+ +P P P+MPP +P
Sbjct: 293 AAPTSTPQKL----IPPQPTGRPS-PAPPAVPPAASPVMPPQTQSP 333
Score = 52.4 bits (124), Expect = 1e-06
Identities = 72/269 (26%), Positives = 92/269 (34%), Gaps = 40/269 (14%)
Query: 333 PWGGTPAPAAGEGPTPDP---WGSSDGGVPVSGPS--ASDPWTPAPAFSDPWGGSPAKPS 387
P GGTP P GP P P G S G P S S P P+ P G P
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQ 66
Query: 388 TNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGS 447
N ++ ++ D + G +G AG P SP G
Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGG---HAGMGPPPSPMDQHSQGYPSP 123
Query: 448 L--AEAVGSPPPAATPTPTPPTRKTP--------------ESFLGPN----------AAL 481
L +E SP PA+ P+ P P + GP A
Sbjct: 124 LGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQ 183
Query: 482 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVP-P 540
+ +++R P P + + + G P G P P P + T P P P
Sbjct: 184 IMAYKMLARGQPLPDHLQMA---VQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP 240
Query: 541 VPG-APPTYISPLG-GGPGLPPMMPPGPP 567
PG APP Y P G GGP +PP P G P
Sbjct: 241 GPGPAPPNYSRPHGMGGPNMPPPGPSGVP 269
Score = 51.2 bits (121), Expect = 3e-06
Identities = 70/261 (26%), Positives = 88/261 (33%), Gaps = 54/261 (20%)
Query: 161 SSAAVGSGPPP----EAEQAWPQSSGEEELQLQLALAMSKEEADQP---PSCGPEDDAQL 213
S G GPPP + Q +P G E A Q P P D A
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159
Query: 214 QLALSLSR--------EEHDKEERIR------RGDDL--RLQMAIEESKRETGGKEESSL 257
Q +R + H +I RG L LQMA++ + G +++
Sbjct: 160 QALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPT 219
Query: 258 MDLADVF-TAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPA 316
+ V T P P P P GP P P GGP +PP P P+
Sbjct: 220 LPPPSVSATGPGPGPGPGPGPGPGP----APPNYSRPHGMGGPNMPP---------PGPS 266
Query: 317 SGDPWRPAAPAGPSVDPW-GGTPAPAAGEGPT------PDPWGSSDGGVPVSGPSAS--- 366
P P P G PW G A AA T P P G P P+AS
Sbjct: 267 GVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM 326
Query: 367 DPWTPAPAFSDPWGGSPAKPS 387
P T +P G PA+P+
Sbjct: 327 PPQTQSP-------GQPAQPA 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.130 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,250,922
Number of Sequences: 37866
Number of extensions: 2488113
Number of successful extensions: 35561
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 455
Number of HSP's successfully gapped in prelim test: 1863
Number of HSP's that attempted gapping in prelim test: 14143
Number of HSP's gapped (non-prelim): 12241
length of query: 576
length of database: 18,247,518
effective HSP length: 108
effective length of query: 468
effective length of database: 14,157,990
effective search space: 6625939320
effective search space used: 6625939320
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.