Search of human proteins with 194239733

Search of human proteins with 194239733

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194239733 solute carrier family 9 (sodium/hydrogen
exchanger), isoform 3 [Homo sapiens]
         (834 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger)...  1642   0.0  
gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ...   774   0.0  
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),...   539   e-153
gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]        499   e-141
gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)...   464   e-130
gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]                218   1e-56
gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),...   213   5e-55
gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), ...   207   4e-53
gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger)...   194   2e-49
gi|14211919 solute carrier family 9, member 7 [Homo sapiens]          189   9e-48
gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]      65   2e-10
gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]           38   0.044
gi|224465231 solute carrier family 9, member 11 [Homo sapiens]         37   0.076
gi|50080201 olfactory receptor, family 7, subfamily G, member 3 ...    36   0.13 
gi|109134347 NY-REN-58 antigen [Homo sapiens]                          36   0.17 
gi|109134355 NY-REN-58 antigen [Homo sapiens]                          36   0.17 
gi|38373673 synaptonemal complex protein 2 [Homo sapiens]              36   0.17 
gi|50233864 olfactory receptor, family 2, subfamily L, member 8 ...    35   0.22 
gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]         34   0.49 
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    34   0.49 
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    34   0.49 
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         34   0.49 
gi|4507401 transcription factor A, mitochondrial [Homo sapiens]        34   0.64 
gi|75677353 AAA-ATPase  TOB3 [Homo sapiens]                            33   0.84 
gi|38788274 bromodomain PHD finger transcription factor isoform ...    32   1.9  
gi|4557255 adenylate cyclase 7 [Homo sapiens]                          32   2.4  
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]                32   2.4  
gi|93277096 limbin [Homo sapiens]                                      32   2.4  
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    32   3.2  
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    32   3.2  

>gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 3 [Homo sapiens]
          Length = 834

 Score = 1642 bits (4252), Expect = 0.0
 Identities = 834/834 (100%), Positives = 834/834 (100%)

Query: 1   MWGLGARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVTFEWAHVQDPYVIAL 60
           MWGLGARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVTFEWAHVQDPYVIAL
Sbjct: 1   MWGLGARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVTFEWAHVQDPYVIAL 60

Query: 61  WILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFTLTPTVFFFYLL 120
           WILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFTLTPTVFFFYLL
Sbjct: 61  WILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFTLTPTVFFFYLL 120

Query: 121 PPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGDLQIGLLD 180
           PPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGDLQIGLLD
Sbjct: 121 PPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGDLQIGLLD 180

Query: 181 FLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGD 240
           FLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGD
Sbjct: 181 FLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGD 240

Query: 241 NVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRIIEPGFVFIISYLSYLT 300
           NVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRIIEPGFVFIISYLSYLT
Sbjct: 241 NVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRIIEPGFVFIISYLSYLT 300

Query: 301 SEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVN 360
           SEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVN
Sbjct: 301 SEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVN 360

Query: 361 PFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAF 420
           PFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAF
Sbjct: 361 PFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAF 420

Query: 421 ALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVKRSEHREPRLNEKLH 480
           ALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVKRSEHREPRLNEKLH
Sbjct: 421 ALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVKRSEHREPRLNEKLH 480

Query: 481 GRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNL 540
           GRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNL
Sbjct: 481 GRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNL 540

Query: 541 KDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQS 600
           KDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQS
Sbjct: 541 KDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQS 600

Query: 601 LEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHRTMRKR 660
           LEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHRTMRKR
Sbjct: 601 LEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHRTMRKR 660

Query: 661 LESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLELSDT 720
           LESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLELSDT
Sbjct: 661 LESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLELSDT 720

Query: 721 EEPPNYDEEMSGGIEFLASVTKDTASDSPAGIDNPVFSPDEALDRSLLARLPPWLSPGET 780
           EEPPNYDEEMSGGIEFLASVTKDTASDSPAGIDNPVFSPDEALDRSLLARLPPWLSPGET
Sbjct: 721 EEPPNYDEEMSGGIEFLASVTKDTASDSPAGIDNPVFSPDEALDRSLLARLPPWLSPGET 780

Query: 781 VVPSQRARTQIPYSPGTFCRLMPFRLSSKSVDSFLQADGPEERPPAALPESTHM 834
           VVPSQRARTQIPYSPGTFCRLMPFRLSSKSVDSFLQADGPEERPPAALPESTHM
Sbjct: 781 VVPSQRARTQIPYSPGTFCRLMPFRLSSKSVDSFLQADGPEERPPAALPESTHM 834


>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 5 [Homo sapiens]
          Length = 896

 Score =  774 bits (1999), Expect = 0.0
 Identities = 424/742 (57%), Positives = 535/742 (72%), Gaps = 22/742 (2%)

Query: 14  LLALALGGLARAGGVEVEPGGAHGESGGFQVVTFEWAHVQDPYVIALWILVASLAKIGFH 73
           LLAL L G A     + E  G      G ++  ++W  V+ PY++ALWILVASLAKI FH
Sbjct: 8   LLALPLAGAAEEPTQKPESPGE--PPPGLELFRWQWHEVEAPYLVALWILVASLAKIVFH 65

Query: 74  LSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFTLTPTVFFFYLLPPIVLDAGYFMPN 133
           LS KVTS+VPES LLI+LGLVLGGIV A    A + L P  FF +LLPPIVLD+GYFMP+
Sbjct: 66  LSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPS 125

Query: 134 RLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGD-LQIGLLDFLLFGSLMAAVD 192
           RLFF NLG IL YAVVGT+WNA TTG +L+G+  +GL+   +Q GLLDFLLFGSL++AVD
Sbjct: 126 RLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVD 185

Query: 193 PVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDCVKGIV 252
           PVAVLAVFEEVHVNE LFIIVFGESLLNDAVTVVLY V  SFV +G  NV   D +KG+ 
Sbjct: 186 PVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVA 245

Query: 253 SFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRIIEPGFVFIISYLSYLTSEMLSLSAILAI 312
           S FVVSLGG  VG+VFAFLL+L TRFTK VRIIEP  VF+++Y +YLT+EM SLSAILA+
Sbjct: 246 SLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAV 305

Query: 313 TFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVL 372
           T CG+ C+KYV+ANIS +S TTV+YTMK LAS AET+IFM LGISAV+   W W++  VL
Sbjct: 306 TMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWAWDSGLVL 365

Query: 373 LTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVK 432
            TL+FI  +RA+GVVLQTW+LN++R+V L+ IDQVV+SYGGLRGAVAFALV+LLD  KV 
Sbjct: 366 GTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVP 425

Query: 433 EKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVKRSEHREPRLNEKLHGRAFDHILSAIE 492
            K+ FV+TTI+VVFFTVI QGLTIKPLV+WLKVKRSEH +P LN++LH   FDHIL+A+E
Sbjct: 426 AKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHILAAVE 485

Query: 493 DISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGER 552
           D+ G  G++Y RD+W  FD+K+LS++LMRRSA + RD+I +V++ LN++DAIS+V +G  
Sbjct: 486 DVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQGGH 545

Query: 553 RGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAE 612
             S   +  PS  +        R+S  E SV+ LLRE+ S  CLD+Q ++   RS RD E
Sbjct: 546 VLSSTGLTLPSMPS--------RNSVAETSVTNLLRESGSGACLDLQVID-TVRSGRDRE 596

Query: 613 DMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKLGLN 672
           D V HH L   LYKPR+ YK   SRH ++    E+QD+E+F + M++RLESFKSTK  + 
Sbjct: 597 DAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNIC 656

Query: 673 QNKKAAKLYKRERAQKR--RNSSIPNGKLP----MESPAQNFTIK-EKDLELSDTEEPPN 725
             K   +  K  R +K    N+   NGK       ++ A   T++ E++ E SD+ E   
Sbjct: 657 FTKSKPRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEK 716

Query: 726 YDEEMSGGIEFLASVTKDTASD 747
            D+E   GI F+A  T +   +
Sbjct: 717 EDDE---GIIFVARATSEVLQE 735


>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
           member 2 [Homo sapiens]
          Length = 812

 Score =  539 bits (1389), Expect = e-153
 Identities = 303/679 (44%), Positives = 417/679 (61%), Gaps = 54/679 (7%)

Query: 30  VEPGGAHGESGGFQVVTFEWAHVQDPYVIALWILVASLAKIGFHLSHKVTSVVPESALLI 89
           V PG    E     V T ++ HVQ P+ I LWIL+ASLAKIGFHL HK+ ++VPES LLI
Sbjct: 56  VAPGTTLFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLI 115

Query: 90  VLGLVLGGIVWAADHIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVV 149
           ++GL+LGGI++  D  +   +   VFF YLLPPIVLDAGYFMP R FF N+GTI  YAVV
Sbjct: 116 MVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVV 175

Query: 150 GTVWNAATTGLSLYGVFLSGLMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVL 209
           GT+WN+   G+SL+G+      G   I LL  LLFGSL++AVDPVAVLAVFE +HVNE L
Sbjct: 176 GTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQL 235

Query: 210 FIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDCVKGIVSFFVVSLGGTLVGVVFA 269
           +I+VFGESLLNDAVTVVLYN+F+SF  +    +  +D   GI +FFVV +GG L+G+   
Sbjct: 236 YILVFGESLLNDAVTVVLYNLFKSFCQM--KTIETIDVFAGIANFFVVGIGGVLIGIFLG 293

Query: 270 FLLSLVTRFTKHVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISE 329
           F+ +  TRFT ++R+IEP FVF+ SYLSY+T+EM  LS I+AIT C +   KYV+ N+S+
Sbjct: 294 FIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQ 353

Query: 330 QSATTVRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQ 389
           +S TT++Y MKML+S +ET+IF+F+G+S V      WN AFV  TL F  ++RA+GV + 
Sbjct: 354 KSYTTIKYFMKMLSSVSETLIFIFMGVSTVGK-NHEWNWAFVCFTLAFCLMWRALGVFVL 412

Query: 390 TWLLNRYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTV 449
           T ++NR+R + L   DQ +++YGGLRGA+ FALV LL       K LF++  I+V+FFTV
Sbjct: 413 TQVINRFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTV 472

Query: 450 IFQGLTIKPLVQWLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSH 509
              G+TI+PLV++L VKRS  ++  ++E+++ R FDH+ + IED+ G  GHN+ RDK+  
Sbjct: 473 FILGITIRPLVEFLDVKRSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKK 532

Query: 510 FDRKFLSRVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVN 569
           FD K+L ++L+R +  KS   I++++ +L +K AI     G                   
Sbjct: 533 FDDKYLRKLLIRENQPKS--SIVSLYKKLEIKHAIEMAETG------------------- 571

Query: 570 VDFTPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQ 629
                  STV    S                 E++ R +  +E       L + LY+ RQ
Sbjct: 572 -----MISTVPTFASL------------NDCREEKIRKVTSSETDEIRELLSRNLYQIRQ 614

Query: 630 EYKHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLYKR------ 683
                Y+RH LT    E+Q +EI  R      ES +     LN+  +A+    R      
Sbjct: 615 RTLS-YNRHSLTADTSERQAKEILIRRRHSLRESIRKDS-SLNREHRASTSTSRYLSLPK 672

Query: 684 -----ERAQKRRNSSIPNG 697
                E+ QKRR  SI +G
Sbjct: 673 NTKLPEKLQKRRTISIADG 691


>gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]
          Length = 815

 Score =  499 bits (1285), Expect = e-141
 Identities = 299/731 (40%), Positives = 440/731 (60%), Gaps = 50/731 (6%)

Query: 42  FQVVTFEWAHVQDPYVIALWILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWA 101
           F V+  ++ HV+ P+ I+LWIL+A L KIGFH+   ++S+VPES LLIV+GL++GG++  
Sbjct: 89  FPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKG 148

Query: 102 ADHIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLS 161
                 F L   VFF +LLPPI+LDAGYF+P R F  NLGTIL++AVVGT+WNA   G  
Sbjct: 149 VGETPPF-LQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGL 207

Query: 162 LYGVFLSGLMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLND 221
           +Y V L G      IGLLD LLFGS+++AVDPVAVLAVFEE+H+NE+L I+VFGESLLND
Sbjct: 208 MYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLND 267

Query: 222 AVTVVLYNVFESFVALGGDNVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKH 281
           AVTVVLY++FE F     ++V  VD   G +SFFVV+LGG LVGVV+  + +  +RFT H
Sbjct: 268 AVTVVLYHLFEEFA--NYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSH 325

Query: 282 VRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKM 341
           +R+IEP FVF+ SY++YL++E+  LS I+A+   G+  + YV+ANIS +S TT++Y +KM
Sbjct: 326 IRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKM 385

Query: 342 LASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQL 401
            +S +ET+IF+FLG+S V      WN  FV+ TL+F  + R +GV+  TW +N++R+V+L
Sbjct: 386 WSSVSETLIFIFLGVSTV-AGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKL 444

Query: 402 EPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQ 461
            P DQ +++YGGLRGA+AF+L  LLD       +LF++  I V+FFTV  QG+TI+PLV 
Sbjct: 445 TPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVD 504

Query: 462 WLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMR 521
            L VK+ +  +  +NE++H +  DH+L+ IEDI G  GH++ +DK + F++K++ + L+ 
Sbjct: 505 LLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIA 564

Query: 522 RSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEA 581
               K   +++  +H++ +K AI  V  G      + + + S  N+      P+S   E 
Sbjct: 565 GERSK-EPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNI-----HPKSLPSER 618

Query: 582 SVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELT 641
            +  L ++            E+  R I           L+  L K RQ  +  Y+RH L 
Sbjct: 619 ILPALSKDK-----------EEEIRKI-----------LRNNLQKTRQRLRS-YNRHTLV 655

Query: 642 PTE-DEKQDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLP 700
               +E  ++ +  R   ++LE   +  L +  +K  +    R R      +  P   LP
Sbjct: 656 ADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLP 715

Query: 701 M--------ESPAQ----NFTIKEKDLELS-DTEEPPNYDEEMSGGIEFLASVTKDTASD 747
           +        +SP      N  +K K L LS D  +    DE+  GGI   +  T    +D
Sbjct: 716 VITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTD 775

Query: 748 ---SPAGIDNP 755
              +PA  D+P
Sbjct: 776 DVFTPAPSDSP 786


>gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger),
           member 4 [Homo sapiens]
          Length = 798

 Score =  464 bits (1194), Expect = e-130
 Identities = 261/626 (41%), Positives = 384/626 (61%), Gaps = 42/626 (6%)

Query: 41  GFQVVTFEWAHVQDPYVIALWILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVW 100
           G  V   ++ +VQ PY + LWIL+ASLAKIGFHL H++  ++PES LLI++G ++GGI++
Sbjct: 56  GISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVGGIIF 115

Query: 101 AADHIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGL 160
             DH +   +  +++F YLLPPIVL+ GYFMP R FF N+G+IL +AV+G + NA   GL
Sbjct: 116 GTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGL 175

Query: 161 SLYGVFLSGLMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLN 220
           SLY +      G   + LL  LLFGSL++AVDPVAVLAVFEE  VNE L++++FGE+LLN
Sbjct: 176 SLYLICQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLN 235

Query: 221 DAVTVVLYNVFESFVALGG-DNVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFT 279
           D +TVVLYN+  +F  +   +++  VD + G   F VV LGG L G+VF F+ + +TRFT
Sbjct: 236 DGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFT 295

Query: 280 KHVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTM 339
           +++  IEP  VF+ SYLSYL +E L LS ILAIT C +  +KYV+ N+S+ S TT++Y M
Sbjct: 296 QNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFM 355

Query: 340 KMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMV 399
           KML+S +ET+IF+F+G+S V      WN AF+  TL F  ++RAI V    ++ N++R  
Sbjct: 356 KMLSSVSETLIFIFMGVSTVGK-NHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTF 414

Query: 400 QLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPL 459
                DQ ++ Y G+RGA +F+L  LL       K +FV+ T++V++FTV  QG+T+ PL
Sbjct: 415 PFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPL 474

Query: 460 VQWLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVL 519
           V++L VK++  +E  +NE+LH R  DH+ + IED+ G   H  +RDK+  FD ++L ++L
Sbjct: 475 VRYLDVKKTNKKE-SINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKIL 533

Query: 520 MRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTV 579
           +R++  KS   I++++ +L +K AI  V  G        I S +  ++      P  +  
Sbjct: 534 IRKNLPKS--SIVSLYKKLEMKQAIEMVETG--------ILSSTAFSI------PHQAQR 577

Query: 580 EASVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHE 639
              +  L  E+V               SIRD         L   +Y+ RQ     Y+++ 
Sbjct: 578 IQGIKRLSPEDV--------------ESIRD--------ILTSNMYQVRQRTLS-YNKYN 614

Query: 640 LTPTEDEKQDREIFHRTMRKRLESFK 665
           L P   EKQ +EI  R      ES +
Sbjct: 615 LKPQTSEKQAKEILIRRQNTLRESMR 640


>gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]
          Length = 581

 Score =  218 bits (556), Expect = 1e-56
 Identities = 150/491 (30%), Positives = 260/491 (52%), Gaps = 36/491 (7%)

Query: 62  ILVASLAKIGFHLSHKVT-SVVPESALLIVLGLVLGGIV----------WAADHIASFTL 110
           +LV ++  I  HL  +     +PES  ++ LG+++G ++          W  + +     
Sbjct: 66  LLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEM----F 121

Query: 111 TPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGL 170
            P +FF  LLPPI+ ++GY +    FF N+G+I L+AV GT  +A   G  +Y  FL   
Sbjct: 122 RPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIY--FLGQA 179

Query: 171 MGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNV 230
               ++ + D   FGSL++AVDPVA +A+F  +HV+ VL ++VFGES+LNDAV++VL N 
Sbjct: 180 DVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNT 239

Query: 231 FESFVALGGDNVTGVDCVKGIVSFFV-----VSLGGTLVGVVFAFLLSLVTRFTKHVRII 285
            E        +V+G       + +F+      +  GTL G++ A +L  +    +    +
Sbjct: 240 AEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHID--LRKTPSL 297

Query: 286 EPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASS 345
           E G + I +YL Y  +E +SLS I+AI F GI    Y   N+S  +   ++ T++ +A  
Sbjct: 298 EFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFL 357

Query: 346 AETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPID 405
            ET +F FLG+S +  F   +  +FV+  +V +   RA+ +   ++LLN +R  ++ P  
Sbjct: 358 CETCVFAFLGLS-IFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKM 416

Query: 406 QVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKV 465
             ++ + GLRGA+ +AL + LD + ++++ L  +TTI++V FT++  G +  PL++ + +
Sbjct: 417 MFIMWFSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDI 476

Query: 466 KRSE-HREPRLN------EKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHF---DRKFL 515
           + ++ HR  + +      EK+        LS + +   +  H   R     F   D K+L
Sbjct: 477 EDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYE-AHYIRRQDLKGFVWLDAKYL 535

Query: 516 SRVLMRRSAQK 526
           +    RR  Q+
Sbjct: 536 NPFFTRRLTQE 546


>gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),
           member 9 [Homo sapiens]
          Length = 645

 Score =  213 bits (543), Expect = 5e-55
 Identities = 140/430 (32%), Positives = 226/430 (52%), Gaps = 27/430 (6%)

Query: 105 IASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYG 164
           +   T  P +FF  LLPPI+  AGY +  R FF NLG+IL YA +GT  +    GL +YG
Sbjct: 124 LEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYG 183

Query: 165 VFLSGLM--GDLQIG---LLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLL 219
            F+  ++  G L+ G     D L FGSLM+A DPV VLA+F E+HV+  L+ ++FGES+L
Sbjct: 184 -FVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVL 242

Query: 220 NDAVTVVLYNVFESFVALGGDNVTGVDCV---KGIVSFFVVSLGGTLVGVVFAFLLSLVT 276
           NDAV +VL   +   +    +N    D     + + +F  +  G   +G  +A + +L+T
Sbjct: 243 NDAVAIVL--TYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLT 300

Query: 277 RFTK--HVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATT 334
           +FTK     ++E G  F++S+ ++L++E   L+ I+A+ FCG+    Y   N+S  S   
Sbjct: 301 KFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIR 360

Query: 335 VRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLN 394
            +   + +   AE +IF ++G++        +N  F+L   + I V RA  +   ++LLN
Sbjct: 361 TKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLN 420

Query: 395 RYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGL 454
             R  ++    Q ++ + GLRGA+AFAL +     + + K +  +TT+++VFFTV   G 
Sbjct: 421 LGRKQKIPWNFQHMMMFSGLRGAIAFALAI--RNTESQPKQMMFTTTLLLVFFTVWVFGG 478

Query: 455 TIKPLVQWLKVKRSEHREPRLNE---KLHGRA--FDHILSAIEDISGQIGHNYLRDKWSH 509
              P++ WL+++     +  L E     H  A   D  ++  E          L   W  
Sbjct: 479 GTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESAR-------LFRMWYS 531

Query: 510 FDRKFLSRVL 519
           FD K+L  +L
Sbjct: 532 FDHKYLKPIL 541


>gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger),
           member 6 isoform b [Homo sapiens]
          Length = 669

 Score =  207 bits (526), Expect = 4e-53
 Identities = 156/482 (32%), Positives = 246/482 (51%), Gaps = 37/482 (7%)

Query: 6   ARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVT---FEWAHVQDPYVIALWI 62
           AR   R L L LA+G    AG  +   GG    +   ++V+    E +H QD   + ++I
Sbjct: 21  ARRLMRPLWLLLAVGVFDWAGASD--GGGGEARAMDEEIVSEKQAEESHRQDSANLLIFI 78

Query: 63  LVASLAKIGFHL-SHKVTSVVPESALLIVLGLVLGGIVWAADHIAS-------------- 107
           L+ +L  +   L  H+    + E+ L ++ GL++G ++    H+ S              
Sbjct: 79  LLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSS 138

Query: 108 -----FTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSL 162
                 T  P VFF  LLPPI+  AGY +  R FF NLG+IL YA +GT  +    G  +
Sbjct: 139 PTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIM 198

Query: 163 YG-VFLSGLMGDL--QIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLL 219
           YG V L  + G L       D LLFG++++A DPV VLA+F E+ V+  L+ ++FGES+L
Sbjct: 199 YGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVL 258

Query: 220 NDAVTVVLYNVFESFVALGGDNVTGVDCV---KGIVSFFVVSLGGTLVGVVFAFLLSLVT 276
           NDAV +VL +   ++    GDN    D     K I  F  +  G   +G     + +LVT
Sbjct: 259 NDAVAIVLSSSIVAYQP-AGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVT 317

Query: 277 RFTK--HVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATT 334
           +FTK    +++E G  F++S+ ++L +E    + ++A+ FCGI    Y   N+S +S   
Sbjct: 318 KFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHR 377

Query: 335 VRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLN 394
            +   ++L   AE  IF ++G++        +N  FV+   V I + RA  +   + LLN
Sbjct: 378 TKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLN 437

Query: 395 RYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTV-IFQG 453
             R  ++    Q ++ + GLRGA+AFAL +         + +  STT+++VFFTV +F G
Sbjct: 438 LGRRSKIGSNFQHMMMFAGLRGAMAFALAI--RDTATYARQMMFSTTLLIVFFTVWVFGG 495

Query: 454 LT 455
            T
Sbjct: 496 GT 497


>gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger),
           member 6 isoform a [Homo sapiens]
          Length = 701

 Score =  194 bits (494), Expect = 2e-49
 Identities = 156/514 (30%), Positives = 246/514 (47%), Gaps = 69/514 (13%)

Query: 6   ARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVT---FEWAHVQDPYVIALWI 62
           AR   R L L LA+G    AG  +   GG    +   ++V+    E +H QD   + ++I
Sbjct: 21  ARRLMRPLWLLLAVGVFDWAGASD--GGGGEARAMDEEIVSEKQAEESHRQDSANLLIFI 78

Query: 63  LVASLAKIGFHL-SHKVTSVVPESALLIVLGLVLGGIVWAADHIAS-------------- 107
           L+ +L  +   L  H+    + E+ L ++ GL++G ++    H+ S              
Sbjct: 79  LLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSS 138

Query: 108 -------------------------------------FTLTPTVFFFYLLPPIVLDAGYF 130
                                                 T  P VFF  LLPPI+  AGY 
Sbjct: 139 PTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYS 198

Query: 131 MPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYG-VFLSGLMGDL--QIGLLDFLLFGSL 187
           +  R FF NLG+IL YA +GT  +    G  +YG V L  + G L       D LLFG++
Sbjct: 199 LKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAI 258

Query: 188 MAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDC 247
           ++A DPV VLA+F E+ V+  L+ ++FGES+LNDAV +VL +   ++    GDN    D 
Sbjct: 259 VSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQP-AGDNSHTFDV 317

Query: 248 V---KGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTK--HVRIIEPGFVFIISYLSYLTSE 302
               K I  F  +  G   +G     + +LVT+FTK    +++E G  F++S+ ++L +E
Sbjct: 318 TAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAE 377

Query: 303 MLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVNPF 362
               + ++A+ FCGI    Y   N+S +S    +   ++L   AE  IF ++G++     
Sbjct: 378 AWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQ 437

Query: 363 IWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAFAL 422
              +N  FV+   V I + RA  +   + LLN  R  ++    Q ++ + GLRGA+AFAL
Sbjct: 438 NHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFAL 497

Query: 423 VVLLDGDKVKEKNLFVSTTIIVVFFTV-IFQGLT 455
            +         + +  STT+++VFFTV +F G T
Sbjct: 498 AI--RDTATYARQMMFSTTLLIVFFTVWVFGGGT 529


>gi|14211919 solute carrier family 9, member 7 [Homo sapiens]
          Length = 725

 Score =  189 bits (480), Expect = 9e-48
 Identities = 153/524 (29%), Positives = 245/524 (46%), Gaps = 70/524 (13%)

Query: 9   PDRGLLLALALG-GLARAGGVEVEPGGAHGESGGF--QVVT---FEWAHVQDPYVIALWI 62
           P R LLL L LG GL  A        GA  E      ++ T    E +H QD   +  +I
Sbjct: 19  PPRLLLLPLLLGWGLRVAAAASASSSGAAAEDSSAMEELATEKEAEESHRQDSVSLLTFI 78

Query: 63  LVASLAKIGFHL-SHKVTSVVPESALLIVLGLVLGGI----------------------- 98
           L+ +L  +   L  H+    + E+ L ++ GL++G I                       
Sbjct: 79  LLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYGTPATSGRDKSLSCTQEDRA 138

Query: 99  ----------------------------VWAADHIASFTLTPTVFFFYLLPPIVLDAGYF 130
                                       V   D +   T  P VFF  LLPPI+  AGY 
Sbjct: 139 FSTLLVNVSGKFFEYTLKGEISPGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYS 198

Query: 131 MPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVF-LSGLMGDL--QIGLLDFLLFGSL 187
           +  R FF NLG+IL YA +GT  +    G  +YGV  L  +MG L  +    D L FG++
Sbjct: 199 LKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFFGAI 258

Query: 188 MAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDC 247
           ++A DPV VLA+F E+H +  L+ ++FGES+LNDAV +VL +   ++    G N    D 
Sbjct: 259 ISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQP-AGLNTHAFDA 317

Query: 248 V---KGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKH--VRIIEPGFVFIISYLSYLTSE 302
               K +  F  +  G   +G V     + VT+FTK     ++E    F++S+ ++L +E
Sbjct: 318 AAFFKSVGIFLGIFSGSFTMGAVTGVNAN-VTKFTKLHCFPLLETALFFLMSWSTFLLAE 376

Query: 303 MLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVNPF 362
               + ++A+ FCGI    Y   N+S +S +  +   ++L   AE  IF ++G++     
Sbjct: 377 ACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFTFQ 436

Query: 363 IWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAFAL 422
              ++  F++   V I + RA  +   ++ LN  R  ++    Q ++ + GLRGA+AFAL
Sbjct: 437 KHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHKIGWNFQHMMMFSGLRGAMAFAL 496

Query: 423 VVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVK 466
            +       ++  +  +TT+++VFFTV   G    P++ WL ++
Sbjct: 497 AIRDTASYARQ--MMFTTTLLIVFFTVWIIGGGTTPMLSWLNIR 538


>gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]
          Length = 1177

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 75/360 (20%), Positives = 146/360 (40%), Gaps = 34/360 (9%)

Query: 55  PYVIALWILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFT----- 109
           P VI    L++S+    F   H     +P   +L +LG     + + +  +  +      
Sbjct: 16  PEVILTLSLISSIG--AFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQW 73

Query: 110 LTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSG 169
           ++P +FF    P +     + M   +       ILL ++ G + N       L  V    
Sbjct: 74  MSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASV---- 129

Query: 170 LMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYN 229
               L +    +LLF +++ + DP+   A   ++ ++  L  ++ GESL+   ++++ + 
Sbjct: 130 --NQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFT 187

Query: 230 V---FESFVALGGDNVTGVDCVKGIVSFFVVS-LGGTLVGVVFAFLLSLVTRFTKHVRII 285
               F+  +    ++    + V GI S+ + S L G L   +  F +S V  F   V  I
Sbjct: 188 SIMDFDQRLQSKRNHTLAEEIVGGICSYIIASFLFGILSSKLIQFWMSTV--FGDDVNHI 245

Query: 286 EPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQK-YVKANISEQSATTVRYTMKMLAS 344
               +F I YL +   E++ +S I  +   G+       KA I E   T +      L+ 
Sbjct: 246 --SLIFSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEE---TLLLEFWTFLSR 300

Query: 345 SAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPI 404
            A  ++F F G+            A   L + F+ +Y ++ + L   +L    ++ + P+
Sbjct: 301 IAFLMVFTFFGLLI---------PAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPV 351


>gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]
          Length = 490

 Score = 37.7 bits (86), Expect = 0.044
 Identities = 49/185 (26%), Positives = 76/185 (41%), Gaps = 24/185 (12%)

Query: 204 HVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDCVKGIVSFFVVSLGGTL 263
           H   V+F+  F   LL     VVL+  F     L    + G   VKG++SF    L G L
Sbjct: 39  HAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQG---VKGLLSFLSAPLIGAL 95

Query: 264 VGVVFAFLLSLVTRFTKHVRI----IEPGFVFIISYLSYLTSEMLSLSAILAITFCGICC 319
             V       L+T F     I    I P + F +          +S+S + A+TF  +  
Sbjct: 96  SDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAV----------ISVSGVFAVTFSVVFA 145

Query: 320 QKYVKANISEQSATTVRYTMKMLASSAETI----IFMFLGISAVNPFIWTWNTAFVLLTL 375
             YV A+I+++   ++ Y +     +A  +    I  +LG    +  +    TA  LL +
Sbjct: 146 --YV-ADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDI 202

Query: 376 VFISV 380
            FI V
Sbjct: 203 CFILV 207


>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
          Length = 1124

 Score = 37.0 bits (84), Expect = 0.076
 Identities = 45/238 (18%), Positives = 93/238 (39%), Gaps = 22/238 (9%)

Query: 129 YFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGDLQI-------GLLDF 181
           YF P  +F   L  +  Y +    W    TGL  +    S ++G + I        L   
Sbjct: 95  YFSPLIIFMVALD-VEFYTLKKMFWQVLLTGLISFST-ASIIIGYVVIKFNKDSWDLQSC 152

Query: 182 LLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFES---FVALG 238
           LLF   +  +DP+  +   + + ++++   ++ GESL+  ++  + +  F       ++ 
Sbjct: 153 LLFSITLGIIDPLRSVNSLKTIGISKIYIDLIRGESLIICSIASIFFGNFRGNRIHFSIF 212

Query: 239 GDNVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRIIEPGFVFIISYLSY 298
            D   G++    I       LG  + G   A ++  +        +      F + Y+++
Sbjct: 213 RDLHVGIELSYDI-------LGSIIFGYWCAKIIQCILADVFSNMLTNIILCFSMVYMTF 265

Query: 299 LTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGI 356
              E L +S  LA+   G+            +    +   +++ +S  E +I+ F GI
Sbjct: 266 YIVEFLGMSGTLALAAVGL---NLDSLTFKPKIELVITKFLRIFSSVYEHLIYAFFGI 320


>gi|50080201 olfactory receptor, family 7, subfamily G, member 3
           [Homo sapiens]
          Length = 312

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 9/158 (5%)

Query: 166 FLSGLMGDLQIGLLDFLLFGSLMAAV---DPVAVLAVFEEVHVNEVLFIIVFGESLLNDA 222
           FL GL GD ++  + F+LF S+  A    + + +LAV  + H++  ++ ++   SL++  
Sbjct: 13  FLLGLSGDPELQPILFMLFLSMYLATMLGNLLIILAVNSDSHLHTPMYFLLSILSLVDIC 72

Query: 223 VTVVLYNVFESFVALGGDNVTGVDCVKGI--VSFFVVSLGGTLVGVVFAFLLSLVTRFTK 280
            T          +     ++    C+  I  V  FV    G LV + +   +++      
Sbjct: 73  FTSTTMPKMLVNIQAQAQSINYTGCLTQICFVLVFVGLENGILVMMAYDRFVAICHPLRY 132

Query: 281 HVRIIEP---GFVFIISYLSYLTSEMLSLSAILAITFC 315
           +V I+ P   G + ++S++  +   +L    +L +TFC
Sbjct: 133 NV-IMNPKLCGLLLLLSFIVSVLDALLHTLMVLQLTFC 169


>gi|109134347 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 35.8 bits (81), Expect = 0.17
 Identities = 36/174 (20%), Positives = 77/174 (44%), Gaps = 12/174 (6%)

Query: 545 SYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQSLEQR 604
           S +AE   R  L  +R      +V ++   +     +     L++ +S++ + + SL Q 
Sbjct: 433 SQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNENSD----LKQQISSLQIQVTSLAQS 488

Query: 605 RRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEK--QDREIFHRTMRKRLE 662
              + ++  M     L++ + + +QE ++  S+ E    E EK  ++++I     + +L 
Sbjct: 489 ENDLLNSNQM-----LKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLH 543

Query: 663 SFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLE 716
             + T      N+   KL +   AQK+R S   N    ++   +    K+++LE
Sbjct: 544 E-RITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELE 596


>gi|109134355 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 35.8 bits (81), Expect = 0.17
 Identities = 36/174 (20%), Positives = 77/174 (44%), Gaps = 12/174 (6%)

Query: 545 SYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQSLEQR 604
           S +AE   R  L  +R      +V ++   +     +     L++ +S++ + + SL Q 
Sbjct: 433 SQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNENSD----LKQQISSLQIQVTSLAQS 488

Query: 605 RRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEK--QDREIFHRTMRKRLE 662
              + ++  M     L++ + + +QE ++  S+ E    E EK  ++++I     + +L 
Sbjct: 489 ENDLLNSNQM-----LKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLH 543

Query: 663 SFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLE 716
             + T      N+   KL +   AQK+R S   N    ++   +    K+++LE
Sbjct: 544 E-RITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELE 596


>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
          Length = 1530

 Score = 35.8 bits (81), Expect = 0.17
 Identities = 43/273 (15%), Positives = 110/273 (40%), Gaps = 40/273 (14%)

Query: 469  EHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVL--------- 519
            + ++ ++ EK  G+ F ++    E +  QI   Y         RK    ++         
Sbjct: 782  DSKQKKMREKSKGKEFTNVA---ESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPV 838

Query: 520  --------MRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVD 571
                     ++S +K +   +NV  E  + D  ++   G            + D ++ + 
Sbjct: 839  VQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNG------------ADDPIIKLG 886

Query: 572  FTPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAED-MVTHHTLQQYLYKPRQE 630
                 +T + + +     + S   +  ++ ++ + S++  +  ++T+H  +        E
Sbjct: 887  IQEFQATAKEACA-----DRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETE 941

Query: 631  YKHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKL--GLNQNKKAAKLYKRERAQK 688
            Y+   S+ +++   + K   ++   +  K +++ KS K    L + + ++K+   +   K
Sbjct: 942  YRCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITK 1001

Query: 689  RRNSSIPNGKLPMESPAQNFTIKEKDLELSDTE 721
            + + +IP G++ +   A       KDL  S++E
Sbjct: 1002 KMDKTIPEGRIRLPRKATKTKKNYKDLSNSESE 1034


>gi|50233864 olfactory receptor, family 2, subfamily L, member 8
           [Homo sapiens]
          Length = 312

 Score = 35.4 bits (80), Expect = 0.22
 Identities = 47/209 (22%), Positives = 94/209 (44%), Gaps = 25/209 (11%)

Query: 167 LSGLMGDLQIGLLDFLL--FGSLMAAVDPVA-VLAVFEEVHVNEVLFIIVFGESLLN-DA 222
           L GL    +I L  F+L  F  LMA +  ++ +L +F + H++  ++ ++   SL++ + 
Sbjct: 13  LLGLFPPSRIDLFFFILIVFIFLMALIGNLSMILLIFLDTHLHTPMYFLLSQLSLIDLNY 72

Query: 223 VTVVLYNVFESFVALGGDNVTGVDCVKGIVSFFVVSLGGTLV----------GVVFAFLL 272
           ++ ++  +   F+  G  +++   C  GI SFF ++LGG              +   F L
Sbjct: 73  ISTIVPKMASDFLH-GNKSISFTGC--GIQSFFFLALGGAEALLLASMAYDRYIAICFPL 129

Query: 273 SLVTRFTKHVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKY----VKANIS 328
             + R +K V ++     +II  ++     +     +L I +C      +    V A ++
Sbjct: 130 HYLIRMSKRVCVLMITGSWIIGSINACAHTVY----VLHIPYCRSRAINHFFCDVPAMVT 185

Query: 329 EQSATTVRYTMKMLASSAETIIFMFLGIS 357
                T  Y   +  S+   ++F F+GIS
Sbjct: 186 LACMDTWVYEGTVFLSATIFLVFPFIGIS 214


>gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]
          Length = 1909

 Score = 34.3 bits (77), Expect = 0.49
 Identities = 29/81 (35%), Positives = 34/81 (41%), Gaps = 20/81 (24%)

Query: 715 LELSDTEEPPNYDEEMSGGIEFLASVTKDTASDSPAGIDNPVFSPDEALDRSLLARLPPW 774
           +E SD+ EPP  DE    G E              AG+ +P   P      SLLAR    
Sbjct: 901 IESSDSGEPPTRDEHCGSGPE--------------AGVKSPSPPPPPGRSVSLLARPSYD 946

Query: 775 LSP------GETVVPSQRART 789
            SP       ET VPS+ ART
Sbjct: 947 YSPAPSSTKSETRVPSETART 967


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 34.3 bits (77), Expect = 0.49
 Identities = 56/293 (19%), Positives = 125/293 (42%), Gaps = 45/293 (15%)

Query: 464 KVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRS 523
           K+ + E    RL++K            +E +  +I    +++K S  + + LS+ LM+  
Sbjct: 492 KILKMEKENQRLSKK------------VEILENEI----VQEKQSLQNCQNLSKDLMKEK 535

Query: 524 AQ---------KSRDRILNVFHELN--LKDAISYVAEGERRGSLAFIRSPSTDNVVNVDF 572
           AQ         ++ +R + +  + N  L   +S + +  +  + A ++    +N +  + 
Sbjct: 536 AQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHES 595

Query: 573 TPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQ-QYLYKPRQEY 631
              +S+  + + +  R+    +  +++  +++     + E+ + H   + + L K     
Sbjct: 596 IKETSSKLSKIEFEKRQ----IKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651

Query: 632 KHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLYKRERAQKRRN 691
           K    + E    E+ + +RE  +R ++K L+SFK+    L   +K       E  + RRN
Sbjct: 652 KITCEKIEALEQENSELERE--NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709

Query: 692 SSIPNGKLPMESPAQNFTIKEKDLELSDTEEPPNYDEEMSGGIEFLASVTKDT 744
             + + K      AQ   ++ K+LE        +  E++  G+E L +  K T
Sbjct: 710 --VESLKCASMKMAQ-LQLENKELE--------SEKEQLKKGLELLKASFKKT 751


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 34.3 bits (77), Expect = 0.49
 Identities = 56/293 (19%), Positives = 125/293 (42%), Gaps = 45/293 (15%)

Query: 464 KVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRS 523
           K+ + E    RL++K            +E +  +I    +++K S  + + LS+ LM+  
Sbjct: 492 KILKMEKENQRLSKK------------VEILENEI----VQEKQSLQNCQNLSKDLMKEK 535

Query: 524 AQ---------KSRDRILNVFHELN--LKDAISYVAEGERRGSLAFIRSPSTDNVVNVDF 572
           AQ         ++ +R + +  + N  L   +S + +  +  + A ++    +N +  + 
Sbjct: 536 AQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHES 595

Query: 573 TPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQ-QYLYKPRQEY 631
              +S+  + + +  R+    +  +++  +++     + E+ + H   + + L K     
Sbjct: 596 IKETSSKLSKIEFEKRQ----IKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651

Query: 632 KHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLYKRERAQKRRN 691
           K    + E    E+ + +RE  +R ++K L+SFK+    L   +K       E  + RRN
Sbjct: 652 KITCEKIEALEQENSELERE--NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709

Query: 692 SSIPNGKLPMESPAQNFTIKEKDLELSDTEEPPNYDEEMSGGIEFLASVTKDT 744
             + + K      AQ   ++ K+LE        +  E++  G+E L +  K T
Sbjct: 710 --VESLKCASMKMAQ-LQLENKELE--------SEKEQLKKGLELLKASFKKT 751


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 34.3 bits (77), Expect = 0.49
 Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 2/103 (1%)

Query: 588 RENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEK 647
           REN+SAV L    LE  R+   + E + +   L + + + ++  K    R +    E ++
Sbjct: 583 RENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQ-QEVETQR 641

Query: 648 QDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLYKRERAQKRR 690
           ++ EI    +RK+ ES K     + +NK    L ++E+ ++ R
Sbjct: 642 KETEIVQLQIRKQEESLKRRSFHI-ENKLKDLLAEKEKFEEER 683


>gi|4507401 transcription factor A, mitochondrial [Homo sapiens]
          Length = 246

 Score = 33.9 bits (76), Expect = 0.64
 Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 12/150 (8%)

Query: 598 MQSLEQRRRSIRDAEDMVTHHTLQQYLYKPR-QEYKHLYSR--HELTPTEDEKQDREIFH 654
           ++ + QR R + D++  +      Q  Y+   Q YK   SR   +LTP++    ++EI  
Sbjct: 81  IRRIAQRWRELPDSKKKI-----YQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMD 135

Query: 655 RTMRKRLESFKS--TKLGLNQNKKAA-KLYKRERAQKRRNSSIPNGKLPMESPAQNFTIK 711
           + ++++  + K   T LG  +  ++A  +Y  ER Q+ +  S       ++   +N +  
Sbjct: 136 KHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDS 195

Query: 712 EKDLELSDT-EEPPNYDEEMSGGIEFLASV 740
           EK+L +    E+   Y  EM    E +  V
Sbjct: 196 EKELYIQHAKEDETRYHNEMKSWEEQMIEV 225


>gi|75677353 AAA-ATPase  TOB3 [Homo sapiens]
          Length = 648

 Score = 33.5 bits (75), Expect = 0.84
 Identities = 45/212 (21%), Positives = 88/212 (41%), Gaps = 34/212 (16%)

Query: 504 RDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPS 563
           +DKWS+FD   L      R+A+ +R+    + H    K+A++     E+           
Sbjct: 44  KDKWSNFDPTGL-----ERAAKAARE----LEHSRYAKEALNLAQMQEQ----------- 83

Query: 564 TDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQY 623
               + ++   +    EA+V  L  E + A        E+RR+++  +E+   H    QY
Sbjct: 84  ---TLQLEQQSKLKEYEAAVEQLKSEQIRA------QAEERRKTL--SEETRQHQARAQY 132

Query: 624 LYK-PRQEYKHLYSRHELTPTED-EKQDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLY 681
             K  RQ Y+    + +L   E+  KQ+  +  +   +R    +  +L         +  
Sbjct: 133 QDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAMRRATVEREMELRHKNEMLRVETE 192

Query: 682 KRERAQ-KRRNSSIPNGKLPMESPAQNFTIKE 712
            R RA+ +R N+ I   ++ +++     T+ E
Sbjct: 193 ARARAKAERENADIIREQIRLKASEHRQTVLE 224


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 28/137 (20%)

Query: 575  RSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAE--------DMVTHHTLQ----- 621
            +SS V+   ++ ++  V+     +Q   QR + +RD +        ++   HTLQ     
Sbjct: 2477 QSSAVQ---THQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQS 2533

Query: 622  -----QYLYKPRQEYKHLYSRHELTPTEDEKQDREIF-HRTMRKRLESFKSTKLGLNQNK 675
                 Q + K     +HL  +  +TP E E+  R I  ++ M+  L+          + K
Sbjct: 2534 EIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKID------KEEK 2587

Query: 676  KAAKLYKRERAQKRRNS 692
            +AAK  KRE + +++ S
Sbjct: 2588 QAAKKRKREESVEQKRS 2604


>gi|4557255 adenylate cyclase 7 [Homo sapiens]
          Length = 1080

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 14/46 (30%), Positives = 24/46 (52%)

Query: 694 IPNGKLPMESPAQNFTIKEKDLELSDTEEPPNYDEEMSGGIEFLAS 739
           +PNG+ P   P ++    ++ +      E  +YD+EM   IE L+S
Sbjct: 513 VPNGRRPKSVPQRHRRTPDRSMSPKGRSEDDSYDDEMLSAIEGLSS 558


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 38/160 (23%), Positives = 64/160 (40%), Gaps = 29/160 (18%)

Query: 612 EDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKLGL 671
           +D +   T  Q   KP Q      +    T + ++KQ R    R++R R ES KST++  
Sbjct: 540 QDRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQR----RSIRTRSESEKSTEV-- 593

Query: 672 NQNKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLELSDTEEPPNYDEEMS 731
                  K  K+E+ +    +++  G            +++   E+SD+ +P       S
Sbjct: 594 ----VPKKKIKKEQVETVPQATVKTG------------LQKGASEISDSCKPLKKRSRAS 637

Query: 732 GGIEFLASVTKDTA-------SDSPAGIDNPVFSPDEALD 764
             +E  +S  +DT+       SD   G    V SP    D
Sbjct: 638 TDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATAD 677


>gi|93277096 limbin [Homo sapiens]
          Length = 1308

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 39/171 (22%), Positives = 69/171 (40%), Gaps = 23/171 (13%)

Query: 620 LQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHR------TMRKRLES-FKSTKLGLN 672
           +Q  L     +  HL  +HE     DE Q   +  R      +++++L++  K  K  L+
Sbjct: 609 VQGLLSTAAAQLTHLIQKHERAGYLDEDQMEMLLERAQTEVFSIKQKLDNDLKQEKKKLH 668

Query: 673 Q---NKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLE-----LSDTEEPP 724
           Q    K+  +L ++ R Q+R  +S+      +E   Q    K   +E     L + +E  
Sbjct: 669 QKLITKRRRELLQKHREQRREQASVGEAFRTVEDAGQYLHQKRSLMEEHGATLEELQE-- 726

Query: 725 NYDEEMSGGIEFLASVTKDTASDSPAGIDNPVFSPDEALDRSLLARLPPWL 775
             D+     +  L     + A+D    + N       A+ + LL R  PWL
Sbjct: 727 RLDQAALDDLRTLTLSLFEKATDELRRLQN------SAMTQELLKRGVPWL 771


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 15/139 (10%)

Query: 587 LRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDE 646
           LR     +    Q  E++RR     E+ +     ++ L + R++   L  + E    E+E
Sbjct: 755 LRRQQEEILRRQQEEERKRRE----EEELARRKQEEALRRQREQEIALRRQRE----EEE 806

Query: 647 KQDREIFHRTMRKRL----ESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPME 702
           +Q +E   R + +R     E  K  +L   Q ++AAK  + E   +RR   +   +L ME
Sbjct: 807 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRR---LEENRLRME 863

Query: 703 SPAQNFTIKEKDLELSDTE 721
             A     +E++ +  + E
Sbjct: 864 EEAARLRHEEEERKRKELE 882


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 15/139 (10%)

Query: 587 LRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDE 646
           LR     +    Q  E++RR     E+ +     ++ L + R++   L  + E    E+E
Sbjct: 782 LRRQQEEILRRQQEEERKRRE----EEELARRKQEEALRRQREQEIALRRQRE----EEE 833

Query: 647 KQDREIFHRTMRKRL----ESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPME 702
           +Q +E   R + +R     E  K  +L   Q ++AAK  + E   +RR   +   +L ME
Sbjct: 834 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRR---LEENRLRME 890

Query: 703 SPAQNFTIKEKDLELSDTE 721
             A     +E++ +  + E
Sbjct: 891 EEAARLRHEEEERKRKELE 909


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,584,402
Number of Sequences: 37866
Number of extensions: 1279722
Number of successful extensions: 4188
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 4109
Number of HSP's gapped (non-prelim): 103
length of query: 834
length of database: 18,247,518
effective HSP length: 111
effective length of query: 723
effective length of database: 14,044,392
effective search space: 10154095416
effective search space used: 10154095416
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.