BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194239697 solute carrier family 1 (glutamate transporter), member 7 [Homo sapiens] (560 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194239697 solute carrier family 1 (glutamate transporter), me... 1092 0.0 gi|169790839 solute carrier family 1 (glial high affinity glutam... 521 e-148 gi|4827012 solute carrier family 1 (high affinity aspartate/glut... 504 e-143 gi|66773030 solute carrier family 1, member 1 [Homo sapiens] 462 e-130 gi|40254478 excitatory amino acid transporter 2 [Homo sapiens] 448 e-126 gi|21314632 solute carrier family 1, member 4 isoform 1 [Homo sa... 390 e-108 gi|5032093 solute carrier family 1 member 5 isoform 1 [Homo sapi... 367 e-101 gi|207444683 solute carrier family 1, member 4 isoform 2 [Homo s... 282 5e-76 gi|223468566 solute carrier family 1 member 5 isoform 3 [Homo sa... 280 2e-75 gi|223468564 solute carrier family 1 member 5 isoform 2 [Homo sa... 277 2e-74 gi|25014103 interleukin 28 receptor, alpha isoform 1 [Homo sapiens] 31 2.6 gi|28416911 interleukin 28 receptor, alpha isoform 3 [Homo sapiens] 31 2.6 gi|28416909 interleukin 28 receptor, alpha isoform 2 [Homo sapiens] 31 2.6 gi|4502193 v-raf murine sarcoma 3611 viral oncogene homolog [Hom... 31 2.6 gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 31 3.4 gi|14249584 hematopoietic SH2 domain containing [Homo sapiens] 30 5.9 gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 30 7.7 gi|239746757 PREDICTED: hypothetical protein XP_002343835 [Homo ... 29 10.0 gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] 29 10.0 gi|14149981 transmembrane protein 117 [Homo sapiens] 29 10.0 gi|56549671 solute carrier family 41, member 3 isoform 2 [Homo s... 29 10.0 gi|56549677 solute carrier family 41, member 3 isoform 4 [Homo s... 29 10.0 gi|56549673 solute carrier family 41, member 3 isoform 1 [Homo s... 29 10.0 >gi|194239697 solute carrier family 1 (glutamate transporter), member 7 [Homo sapiens] Length = 560 Score = 1092 bits (2823), Expect = 0.0 Identities = 560/560 (100%), Positives = 560/560 (100%) Query: 1 MVPHAILARGRDVCRRNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYFQFPGELLMRM 60 MVPHAILARGRDVCRRNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYFQFPGELLMRM Sbjct: 1 MVPHAILARGRDVCRRNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYFQFPGELLMRM 60 Query: 61 LKMMILPLVVSSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAA 120 LKMMILPLVVSSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAA Sbjct: 61 LKMMILPLVVSSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAA 120 Query: 121 QKETTEQSGKPIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPR 180 QKETTEQSGKPIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPR Sbjct: 121 QKETTEQSGKPIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPR 180 Query: 181 RILIYGVQEENGSHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMG 240 RILIYGVQEENGSHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMG Sbjct: 181 RILIYGVQEENGSHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMG 240 Query: 241 DSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTV 300 DSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTV Sbjct: 241 DSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTV 300 Query: 301 VCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNH 360 VCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNH Sbjct: 301 VCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNH 360 Query: 361 IDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAA 420 IDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAA Sbjct: 361 IDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAA 420 Query: 421 GIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD 480 GIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD Sbjct: 421 GIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD 480 Query: 481 FARDTGTEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEE 540 FARDTGTEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEE Sbjct: 481 FARDTGTEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEE 540 Query: 541 LPAASLNHCTIQISELETNV 560 LPAASLNHCTIQISELETNV Sbjct: 541 LPAASLNHCTIQISELETNV 560 >gi|169790839 solute carrier family 1 (glial high affinity glutamate transporter), member 3 [Homo sapiens] Length = 542 Score = 521 bits (1343), Expect = e-148 Identities = 281/506 (55%), Positives = 356/506 (70%), Gaps = 36/506 (7%) Query: 16 RNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYFQFPGELLMRMLKMMILPLVVSSLMS 75 RN ++L+V +VIVG +LGF LR R+S +E+ YF FPGELLMRML+M++LPL++SSL++ Sbjct: 47 RNAFVLLTVTAVIVGTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVT 106 Query: 76 GLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETTEQSGKPI-MS 134 G+A+LD+K S ++G+ V YY+ TT +AV++GI +V IIHPG KE + GK + ++ Sbjct: 107 GMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGT-KENMHREGKIVRVT 165 Query: 135 SADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQEENGSH 194 +ADA LDLIRNMFP NLVEA FKQ++T + E + G N S Sbjct: 166 AADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANET------LVGAVINNVSE 219 Query: 195 VQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLN 254 +T V PG+ +G+N LG+V FS G ++G M + G L F LN Sbjct: 220 AMETLTRITEELVPV----PGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLN 275 Query: 255 ESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFILPL 314 E++M++VAV +WY P GI+FLIAGKI+EM+D +G +L Y+VTV+ GL++H + +LPL Sbjct: 276 EAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPL 335 Query: 315 LYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGA 374 LYF +T+KNP VFI G+LQAL+ AL TSSSSATLPITFKCL ENN +D+R+ RFVLPVGA Sbjct: 336 LYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGA 395 Query: 375 TINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVL 434 TINMDGTALYEA+AAIFIAQVNN+EL+FGQIITISITATAASIGAAGIPQAGLVTMVIVL Sbjct: 396 TINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVL 455 Query: 435 TSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD-------------- 480 TSVGLPTDDITLIIAVDW LDR RT NVLGD+L AGI+ H+ R + Sbjct: 456 TSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIE 515 Query: 481 ----------FARDTGTEKLLPCETK 496 A+D TEK + ETK Sbjct: 516 ENEMKKPYQLIAQDNETEKPIDSETK 541 >gi|4827012 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 [Homo sapiens] Length = 564 Score = 504 bits (1299), Expect = e-143 Identities = 271/503 (53%), Positives = 358/503 (71%), Gaps = 11/503 (2%) Query: 15 RRNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYFQFPGELLMRMLKMMILPLVVSSLM 74 RRN ++L+V +V++G L F LR +L+ ++I YF FPGELLMRML+M++LPL+VSSL+ Sbjct: 54 RRNAFILLTVSAVVIGVSLAFALRPYQLTYRQIKYFSFPGELLMRMLQMLVLPLIVSSLV 113 Query: 75 SGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETTEQSGKPIMS 134 +G+ASLD K + R+G+ YY+ TT +AV +GI MV+IIHPG +++ + + Sbjct: 114 TGMASLDNKATGRMGMRAAVYYMVTTIIAVFIGILMVTIIHPGKGSKEGLHREGRIETIP 173 Query: 135 SADALLDLIRNMFPANLVEATFKQYRTK-TTPVVKSPKVAPEE-APPRRILIYGVQEENG 192 +ADA +DLIRNMFP NLVEA FKQ++T+ +T VV V E + P + ENG Sbjct: 174 TADAFMDLIRNMFPPNLVEACFKQFKTQYSTRVVTRTMVRTENGSEPGASMPPPFSVENG 233 Query: 193 -SHVQNFALDLTPPPEVVYKSE----PGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLV 247 S ++N L E++ E PG+++G+N LG+V FS G+++G M G L Sbjct: 234 TSFLENVTRALGTLQEMLSFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLR 293 Query: 248 SFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLH 307 F LNE++M++V + +WY P GI+FLIAGKILEM+D +G +LG Y++TV+ GL LH Sbjct: 294 DFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLH 353 Query: 308 GLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIAR 367 +LPL+YF +T +NP FI G+LQAL+ A+ TSSSSATLPITF+CL E +DRRI R Sbjct: 354 AGIVLPLIYFLVTHRNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITR 413 Query: 368 FVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGL 427 FVLPVGAT+NMDGTALYEA+AAIFIAQVNNYEL+ GQI TISITATAAS+GAAGIPQAGL Sbjct: 414 FVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGL 473 Query: 428 VTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFARDTGT 487 VTMVIVLTSVGLPT+DITLIIAVDW LDR RTM NVLGD++ A ++ H+ +++ Sbjct: 474 VTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELELQE-A 532 Query: 488 EKLLPCETKPVSLQEIVAAQQNG 510 E LP KP + + AQ+ G Sbjct: 533 ELTLPSLGKP---YKSLMAQEKG 552 >gi|66773030 solute carrier family 1, member 1 [Homo sapiens] Length = 524 Score = 462 bits (1188), Expect = e-130 Identities = 247/468 (52%), Positives = 330/468 (70%), Gaps = 16/468 (3%) Query: 15 RRNGLLILSVLSVIVGCLLGFFLRTR-RLSPQEISYFQFPGELLMRMLKMMILPLVVSSL 73 + N +L+ +V +V++G G +R LS E YF FPGE+LMRMLK++ILPL++SS+ Sbjct: 16 KNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISSM 75 Query: 74 MSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETTEQSGK-PI 132 ++G+A+LD+ S ++G+ V YY TT +AVI+GI +V I PG + ++G P Sbjct: 76 ITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTPE 135 Query: 133 MSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQEENG 192 +S+ DA+LDLIRNMFP NLV+A F+QY+TK V P PE + EE+ Sbjct: 136 VSTVDAMLDLIRNMFPENLVQACFQQYKTKREEV--KPPSDPE---------MNMTEESF 184 Query: 193 SHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQC 252 + V A+ E YK SDG+NVLG++ F G+++G+MG+ G LV F Sbjct: 185 TAVMTTAISKNKTKE--YKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNA 242 Query: 253 LNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFIL 312 L+++ MKIV + + Y P GI+FLIAGKI+E++D + +KLG Y TV+ GL +H + IL Sbjct: 243 LSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWE-IFRKLGLYMATVLTGLAIHSIVIL 301 Query: 313 PLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPV 372 PL+YF + +KNP F G+ QALL AL SSSSATLP+TF+C ENN +D+RI RFVLPV Sbjct: 302 PLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPV 361 Query: 373 GATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVI 432 GATINMDGTALYEAVAA+FIAQ+N+ +L GQIITISITAT+ASIGAAG+PQAGLVTMVI Sbjct: 362 GATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVI 421 Query: 433 VLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD 480 VL++VGLP +D+TLIIAVDW LDRFRTM+NVLGDA GI+ + +K+ Sbjct: 422 VLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKE 469 >gi|40254478 excitatory amino acid transporter 2 [Homo sapiens] Length = 574 Score = 448 bits (1153), Expect = e-126 Identities = 236/471 (50%), Positives = 317/471 (67%), Gaps = 11/471 (2%) Query: 12 DVCRRNGLLILSVLSVIVGCLLGFFLRTRR-LSPQEISYFQFPGELLMRMLKMMILPLVV 70 D +N LL L+V VI+G + G LR + P + FPG++LMRMLKM+ILPL++ Sbjct: 39 DKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLII 98 Query: 71 SSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETTEQSGK 130 SSL++GL+ LDAK S RLG + YY+ TT +A ++G+ +V IHPG+ K+ K Sbjct: 99 SSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKK 158 Query: 131 -PIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQE 189 +SS DA LDLIRN+FP NLV+A F+Q +T T V+ +P P+E + + Sbjct: 159 NDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPP--PDEEANATSAVVSLLN 216 Query: 190 ENGSHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLVSF 249 E + V ++V K DGMNVLG++ F GI +G+MGD +V F Sbjct: 217 ETVTEVPE-------ETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDF 269 Query: 250 CQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLHGL 309 LNE VMK+V + +WY P GI LI GKI+ + D V ++LG Y VTV+ GL++HG Sbjct: 270 FNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGG 329 Query: 310 FILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFV 369 LPL+YF +T+KNP F GI QA + AL T+SS+ TLP+TF+CL EN ID+R+ RFV Sbjct: 330 IFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFV 389 Query: 370 LPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVT 429 LPVGATINMDGTALYEAVAAIFIAQ+N LD GQI+T+S+TAT AS+GAA IP AGLVT Sbjct: 390 LPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVT 449 Query: 430 MVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD 480 M+++LT+VGLPT+DI+L++AVDW LDR RT +NV+GD+ AGI+ H+ + + Sbjct: 450 MLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSE 500 >gi|21314632 solute carrier family 1, member 4 isoform 1 [Homo sapiens] Length = 532 Score = 390 bits (1002), Expect = e-108 Identities = 218/493 (44%), Positives = 305/493 (61%), Gaps = 44/493 (8%) Query: 15 RRNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYFQFPGELLMRMLKMMILPLVVSSLM 74 RR L++L+V V+ G LG LR LS +++Y FPGE+L+RML+M+ILPLVV SL+ Sbjct: 40 RRQALVLLTVSGVLAGAGLGAALRGLSLSRTQVTYLAFPGEMLLRMLRMIILPLVVCSLV 99 Query: 75 SGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETT-----EQSG 129 SG ASLDA RLG + VAY+ TT A + + + II PGS AQ + E SG Sbjct: 100 SGAASLDASCLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGSGAQTLQSSDLGLEDSG 159 Query: 130 KPIM--SSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGV 187 P + + D+ LDL RN+FP+NLV A F+ Y T Y V Sbjct: 160 PPPVPKETVDSFLDLARNLFPSNLVVAAFRTYATD----------------------YKV 197 Query: 188 QEENGSHVQNFALDLTPPPEVVYKSEP-GTS-DGMNVLGIVFFSATMGIMLGRMGDSGAP 245 +N S V ++ P GT +GMN+LG+V F+ +G+ L ++G G Sbjct: 198 VTQNSSS-----------GNVTHEKIPIGTEIEGMNILGLVLFALVLGVALKKLGSEGED 246 Query: 246 LVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLV 305 L+ F LNE+ M +V+ +WY P GI+FL+ KI+EM D + LG Y + G V Sbjct: 247 LIRFFNSLNEATMVLVSWIMWYVPVGIMFLVGSKIVEMKDIIVLVTSLGKYIFASILGHV 306 Query: 306 LHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRI 365 +HG +LPL+YF T+KNP F+ G+L A AT SSSATLP KC+ ENN +D+RI Sbjct: 307 IHGGIVLPLIYFVFTRKNPFRFLLGLLAPFATAFATCSSSATLPSMMKCIEENNGVDKRI 366 Query: 366 ARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQA 425 +RF+LP+GAT+NMDG A+++ VAA+FIAQ+NN EL+ GQI TI +TATA+S+GAAG+P Sbjct: 367 SRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVELNAGQIFTILVTATASSVGAAGVPAG 426 Query: 426 GLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFARDT 485 G++T+ I+L ++GLPT D+ LI+AVDW +DR T++NV GDAL AGI+ H+ +K A Sbjct: 427 GVLTIAIILEAIGLPTHDLPLILAVDWIVDRTTTVVNVEGDALGAGILHHLNQK--ATKK 484 Query: 486 GTEKLLPCETKPV 498 G ++L + + + Sbjct: 485 GEQELAEVKVEAI 497 >gi|5032093 solute carrier family 1 member 5 isoform 1 [Homo sapiens] Length = 541 Score = 367 bits (942), Expect = e-101 Identities = 210/507 (41%), Positives = 303/507 (59%), Gaps = 51/507 (10%) Query: 11 RDVCRRNGLLILSVLSVIVGCLLGFFLR----TRRLSPQEISYFQFPGELLMRMLKMMIL 66 R R N L++L+V++V+ G LG + L P+ +S F FPGELL+R+L+M+IL Sbjct: 46 RRCLRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIIL 105 Query: 67 PLVVSSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPG--SAAQKET 124 PLVV SL+ G ASLD RLG + ++L TT +A +G+ + + PG SAA + Sbjct: 106 PLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINAS 165 Query: 125 TEQSGK----PIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPR 180 +G P D+ LDL RN+FP+NLV A F+ Y T Sbjct: 166 VGAAGSAENAPSKEVLDSFLDLARNIFPSNLVSAAFRSYSTT------------------ 207 Query: 181 RILIYGVQEENGSHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMG 240 Y + G+ V+ P + V +GMN+LG+V F+ G+ L ++G Sbjct: 208 ----YEERNITGTRVK------VPVGQEV--------EGMNILGLVVFAIVFGVALRKLG 249 Query: 241 DSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTV 300 G L+ F NE+ M +V+ +WY P GI+FL+AGKI+EM+D + +LG Y + Sbjct: 250 PEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCC 309 Query: 301 VCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNH 360 + G +HGL +LPL+YF T+KNP F+ GI+ L A TSSSSATLP+ KC+ ENN Sbjct: 310 LLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNG 369 Query: 361 IDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAA 420 + + I+RF+LP+GAT+NMDG AL++ VAA+FIAQ++ LDF +IITI +TATA+S+GAA Sbjct: 370 VAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAA 429 Query: 421 GIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD 480 GIP G++T+ I+L +V LP D I+LI+AVDW +DR T++NV GDAL AG++ + + Sbjct: 430 GIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDRT 489 Query: 481 FARDTGTEKL-----LPCETKPVSLQE 502 +R T E + LP + PV +E Sbjct: 490 ESRSTEPELIQVKSELPLDPLPVPTEE 516 >gi|207444683 solute carrier family 1, member 4 isoform 2 [Homo sapiens] Length = 312 Score = 282 bits (722), Expect = 5e-76 Identities = 136/279 (48%), Positives = 195/279 (69%), Gaps = 2/279 (0%) Query: 220 MNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGK 279 MN+LG+V F+ +G+ L ++G G L+ F LNE+ M +V+ +WY P GI+FL+ K Sbjct: 1 MNILGLVLFALVLGVALKKLGSEGEDLIRFFNSLNEATMVLVSWIMWYVPVGIMFLVGSK 60 Query: 280 ILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIAL 339 I+EM D + LG Y + G V+HG +LPL+YF T+KNP F+ G+L A Sbjct: 61 IVEMKDIIVLVTSLGKYIFASILGHVIHGGIVLPLIYFVFTRKNPFRFLLGLLAPFATAF 120 Query: 340 ATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYE 399 AT SSSATLP KC+ ENN +D+RI+RF+LP+GAT+NMDG A+++ VAA+FIAQ+NN E Sbjct: 121 ATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVE 180 Query: 400 LDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRT 459 L+ GQI TI +TATA+S+GAAG+P G++T+ I+L ++GLPT D+ LI+AVDW +DR T Sbjct: 181 LNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLPLILAVDWIVDRTTT 240 Query: 460 MINVLGDALAAGIMAHICRKDFARDTGTEKLLPCETKPV 498 ++NV GDAL AGI+ H+ +K A G ++L + + + Sbjct: 241 VVNVEGDALGAGILHHLNQK--ATKKGEQELAEVKVEAI 277 >gi|223468566 solute carrier family 1 member 5 isoform 3 [Homo sapiens] Length = 339 Score = 280 bits (717), Expect = 2e-75 Identities = 139/290 (47%), Positives = 200/290 (68%), Gaps = 5/290 (1%) Query: 218 DGMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIA 277 +GMN+LG+V F+ G+ L ++G G L+ F NE+ M +V+ +WY P GI+FL+A Sbjct: 25 EGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVA 84 Query: 278 GKILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLI 337 GKI+EM+D + +LG Y + + G +HGL +LPL+YF T+KNP F+ GI+ L Sbjct: 85 GKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLAT 144 Query: 338 ALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNN 397 A TSSSSATLP+ KC+ ENN + + I+RF+LP+GAT+NMDG AL++ VAA+FIAQ++ Sbjct: 145 AFGTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQ 204 Query: 398 YELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRF 457 LDF +IITI +TATA+S+GAAGIP G++T+ I+L +V LP D I+LI+AVDW +DR Sbjct: 205 QSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRS 264 Query: 458 RTMINVLGDALAAGIMAHICRKDFARDTGTEKL-----LPCETKPVSLQE 502 T++NV GDAL AG++ + + +R T E + LP + PV +E Sbjct: 265 CTVLNVEGDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPVPTEE 314 >gi|223468564 solute carrier family 1 member 5 isoform 2 [Homo sapiens] Length = 313 Score = 277 bits (709), Expect = 2e-74 Identities = 138/288 (47%), Positives = 198/288 (68%), Gaps = 5/288 (1%) Query: 220 MNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGK 279 MN+LG+V F+ G+ L ++G G L+ F NE+ M +V+ +WY P GI+FL+AGK Sbjct: 1 MNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGK 60 Query: 280 ILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIAL 339 I+EM+D + +LG Y + + G +HGL +LPL+YF T+KNP F+ GI+ L A Sbjct: 61 IVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAF 120 Query: 340 ATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYE 399 TSSSSATLP+ KC+ ENN + + I+RF+LP+GAT+NMDG AL++ VAA+FIAQ++ Sbjct: 121 GTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQS 180 Query: 400 LDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRT 459 LDF +IITI +TATA+S+GAAGIP G++T+ I+L +V LP D I+LI+AVDW +DR T Sbjct: 181 LDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCT 240 Query: 460 MINVLGDALAAGIMAHICRKDFARDTGTEKL-----LPCETKPVSLQE 502 ++NV GDAL AG++ + + +R T E + LP + PV +E Sbjct: 241 VLNVEGDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPVPTEE 288 >gi|25014103 interleukin 28 receptor, alpha isoform 1 [Homo sapiens] Length = 520 Score = 31.2 bits (69), Expect = 2.6 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 11/63 (17%) Query: 487 TEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEELPAASL 546 T +L PC P+ L+ VA + G A TL P PH PVQ+ PAAS Sbjct: 144 TYQLPPC-MPPLDLKYEVAFWKEG-------AGNKTLFPVTPHGQPVQITLQ---PAASE 192 Query: 547 NHC 549 +HC Sbjct: 193 HHC 195 >gi|28416911 interleukin 28 receptor, alpha isoform 3 [Homo sapiens] Length = 244 Score = 31.2 bits (69), Expect = 2.6 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 11/63 (17%) Query: 487 TEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEELPAASL 546 T +L PC P+ L+ VA + G A TL P PH PVQ+ PAAS Sbjct: 144 TYQLPPC-MPPLDLKYEVAFWKEG-------AGNKTLFPVTPHGQPVQITLQ---PAASE 192 Query: 547 NHC 549 +HC Sbjct: 193 HHC 195 >gi|28416909 interleukin 28 receptor, alpha isoform 2 [Homo sapiens] Length = 491 Score = 31.2 bits (69), Expect = 2.6 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 11/63 (17%) Query: 487 TEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEELPAASL 546 T +L PC P+ L+ VA + G A TL P PH PVQ+ PAAS Sbjct: 144 TYQLPPC-MPPLDLKYEVAFWKEG-------AGNKTLFPVTPHGQPVQITLQ---PAASE 192 Query: 547 NHC 549 +HC Sbjct: 193 HHC 195 >gi|4502193 v-raf murine sarcoma 3611 viral oncogene homolog [Homo sapiens] Length = 606 Score = 31.2 bits (69), Expect = 2.6 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 6/89 (6%) Query: 269 PFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFI 328 P G V +A +++ M DP F S G+VL+ L L Y I ++ I+F+ Sbjct: 466 PSGSVLWMAAEVIRMQDP----NPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFM 521 Query: 329 --RGILQALLIALATSSSSATLPITFKCL 355 RG L L ++++ A + CL Sbjct: 522 VGRGYLSPDLSKISSNCPKAMRRLLSDCL 550 >gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] Length = 408 Score = 30.8 bits (68), Expect = 3.4 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 413 TAASIGAAGIP-QAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAA 470 TA + G G+P +A L ++ L + ++ +I+A+ W R +TM NV +LAA Sbjct: 24 TANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWT-PRLQTMTNVFVTSLAA 81 >gi|14249584 hematopoietic SH2 domain containing [Homo sapiens] Length = 352 Score = 30.0 bits (66), Expect = 5.9 Identities = 20/68 (29%), Positives = 26/68 (38%) Query: 130 KPIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQE 189 KPI + L R PAN+ Y P APEEA P+ +L + +E Sbjct: 112 KPIEPRRELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKE 171 Query: 190 ENGSHVQN 197 S N Sbjct: 172 RKPSAEMN 179 >gi|42476169 Paf1, RNA polymerase II associated factor, homolog [Homo sapiens] Length = 531 Score = 29.6 bits (65), Expect = 7.7 Identities = 22/108 (20%), Positives = 42/108 (38%), Gaps = 16/108 (14%) Query: 152 VEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQEENGSHVQNFALDLTPPPEVVYK 211 +E TF+ + + P+V P E P +F + + P +V++ Sbjct: 179 IEKTFEDAQKSISQHYSKPRVTPVEVMP--------------VFPDFKMWINPCAQVIFD 224 Query: 212 SEPGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMK 259 S+P D + S M + G M + G V++ + E++ K Sbjct: 225 SDPAPKDTSGAAALEMMSQAM--IRGMMDEEGNQFVAYFLPVEETLKK 270 >gi|239746757 PREDICTED: hypothetical protein XP_002343835 [Homo sapiens] Length = 281 Score = 29.3 bits (64), Expect = 10.0 Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 3/52 (5%) Query: 492 PCETKPVS---LQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEE 540 PC +S L V +Q C S A A + P+CP +P+ +D++ Sbjct: 25 PCNVASISWHPLTHYVLGKQLNCKASRALARDRAGAPSCPAGIPIVCSEDDQ 76 >gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] Length = 2078 Score = 29.3 bits (64), Expect = 10.0 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 106 VGIFMVSIIHPGSAAQKETTEQSGKPIMSSADALLDLIRNMFPANLVEATFKQYR 160 VG F +S++H + ET+ Q+ P+ A A I + PA FK +R Sbjct: 511 VGTFSISVLHIDPLSPPETS-QNLNPLTPMAVAFFTCIEKIDPARFSTEDFKSFR 564 >gi|14149981 transmembrane protein 117 [Homo sapiens] Length = 514 Score = 29.3 bits (64), Expect = 10.0 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Query: 222 VLGIVFFSATMGIMLGRMGDSGAPLVS-FCQCLNESVMKIVAVAVWYFPFGIVFLIAGKI 280 +L + FS +L G+ GA +++ + NES MK+ AV W F +++ + Sbjct: 116 ILFLFIFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMM 175 Query: 281 LE 282 L+ Sbjct: 176 LQ 177 >gi|56549671 solute carrier family 41, member 3 isoform 2 [Homo sapiens] Length = 487 Score = 29.3 bits (64), Expect = 10.0 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 22/157 (14%) Query: 319 ITKKNPIVFIRGILQALLIA-LATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATIN 377 +T P+V ++G L+ L + L+T++++ + + ++ I +A ++ V AT+ Sbjct: 103 LTLVPPLVGLKGNLEMTLASRLSTAANTGQIDDPQE---QHRVISSNLA--LIQVQATV- 156 Query: 378 MDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSV 437 L AVAA+ + V+ E+D ++ + ++ + AA +V +VI + Sbjct: 157 ---VGLLAAVAALLLGVVSREEVDVAKVELLCASSVLTAFLAAFALGVLMVCIVIGARKL 213 Query: 438 GLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMA 474 G+ D+I IA LGD + I+A Sbjct: 214 GVNPDNIATPIAAS------------LGDLITLSILA 238 >gi|56549677 solute carrier family 41, member 3 isoform 4 [Homo sapiens] Length = 461 Score = 29.3 bits (64), Expect = 10.0 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 22/157 (14%) Query: 319 ITKKNPIVFIRGILQALLIA-LATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATIN 377 +T P+V ++G L+ L + L+T++++ + + ++ I +A ++ V AT+ Sbjct: 77 LTLVPPLVGLKGNLEMTLASRLSTAANTGQIDDPQE---QHRVISSNLA--LIQVQATV- 130 Query: 378 MDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSV 437 L AVAA+ + V+ E+D ++ + ++ + AA +V +VI + Sbjct: 131 ---VGLLAAVAALLLGVVSREEVDVAKVELLCASSVLTAFLAAFALGVLMVCIVIGARKL 187 Query: 438 GLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMA 474 G+ D+I IA LGD + I+A Sbjct: 188 GVNPDNIATPIAAS------------LGDLITLSILA 212 >gi|56549673 solute carrier family 41, member 3 isoform 1 [Homo sapiens] Length = 507 Score = 29.3 bits (64), Expect = 10.0 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 22/157 (14%) Query: 319 ITKKNPIVFIRGILQALLIA-LATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATIN 377 +T P+V ++G L+ L + L+T++++ + + ++ I +A ++ V AT+ Sbjct: 103 LTLVPPLVGLKGNLEMTLASRLSTAANTGQIDDPQE---QHRVISSNLA--LIQVQATV- 156 Query: 378 MDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSV 437 L AVAA+ + V+ E+D ++ + ++ + AA +V +VI + Sbjct: 157 ---VGLLAAVAALLLGVVSREEVDVAKVELLCASSVLTAFLAAFALGVLMVCIVIGARKL 213 Query: 438 GLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMA 474 G+ D+I IA LGD + I+A Sbjct: 214 GVNPDNIATPIAAS------------LGDLITLSILA 238 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.138 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,246,747 Number of Sequences: 37866 Number of extensions: 798135 Number of successful extensions: 2831 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 2808 Number of HSP's gapped (non-prelim): 25 length of query: 560 length of database: 18,247,518 effective HSP length: 107 effective length of query: 453 effective length of database: 14,195,856 effective search space: 6430722768 effective search space used: 6430722768 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.