Guide to the Human Genome
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Name: HSH2D Sequence: fasta or formatted (352aa) NCBI GI: 14249584
Description:

hematopoietic SH2 domain containing

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         23           2
 C cysteine            2.6          9           2
 D aspartate           4.8         17           2
 E glutamate           7.4         26           2
 F phenylalanine       2.3          8           1
 G glycine             5.7         20           1
 H histidine           3.4         12           1
 I isoleucine          2.0          7           1
 K lysine              5.7         20           1
 L leucine             9.1         32           2
 M methionine          2.0          7           1
 N asparagine          1.7          6           1
 P proline             9.9         35           3
 Q glutamine           6.5         23           2
 R arginine            6.0         21           2
 S serine              9.9         35           2
 T threonine           5.4         19           2
 V valine              6.0         21           2
 W tryptophan          1.1          4           1
 Y tyrosine            2.0          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hematopoietic SH2 domain containing 
SH2D7                 0.110   SH2 domain containing 7 
SH2D2A                0.101   SH2 domain protein 2A isoform 4 
SH2D2A                0.101   SH2 domain protein 2A isoform 3 
SH2D2A                0.101   SH2 domain protein 2A isoform 2 
SH2D2A                0.101   SH2 domain protein 2A isoform 2 
SH2D2A                0.088   SH2 domain protein 2A isoform 1 
SH2D4A                0.077   SH2 domain containing 4A 
GRAP2                 0.043   GRB2-related adaptor protein 2 
SRMS                  0.041   src-related kinase lacking C-terminal regulatory tyr...
FRK                   0.033   fyn-related kinase 
FER                   0.031   fer (fps/fes related) tyrosine kinase 
PTK6                  0.030   PTK6 protein tyrosine kinase 6 
ABL1                  0.030   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.030   c-abl oncogene 1, receptor tyrosine kinase isoform b...
SHE                   0.030   Src homology 2 domain containing E 
CRKL                  0.029   v-crk sarcoma virus CT10 oncogene homolog (avian)-lik...
SYK                   0.029   spleen tyrosine kinase isoform 2 
SYK                   0.029   spleen tyrosine kinase isoform 1 
FES                   0.029   feline sarcoma oncogene isoform 2 
FES                   0.029   feline sarcoma oncogene isoform 1 
HCK                   0.029   hemopoietic cell kinase isoform p61HCK 
ABL2                  0.027   arg tyrosine kinase isoform c 
ABL2                  0.027   arg tyrosine kinase isoform b 
ABL2                  0.027   arg tyrosine kinase isoform e 
ABL2                  0.027   arg tyrosine kinase isoform d 
ABL2                  0.027   arg tyrosine kinase isoform a 
NCK2                  0.027   NCK adaptor protein 2 isoform A 
NCK2                  0.027   NCK adaptor protein 2 isoform A 
TXK                   0.027   TXK tyrosine kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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