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Search of human proteins with 194097375
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens]
(452 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens] 927 0.0
gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens] 419 e-117
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 231 1e-60
gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 229 4e-60
gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 229 4e-60
gi|169208819 PREDICTED: similar to kinase D-interacting substrat... 58 2e-08
gi|169208593 PREDICTED: similar to kinase D-interacting substrat... 58 2e-08
gi|169208169 PREDICTED: similar to kinase D-interacting substrat... 56 6e-08
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 55 1e-07
gi|41327754 ankyrin repeat domain 3 [Homo sapiens] 53 6e-07
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ... 53 6e-07
gi|70995267 ankyrin repeat domain 29 [Homo sapiens] 53 6e-07
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 52 8e-07
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 52 8e-07
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 52 8e-07
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 52 8e-07
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 52 8e-07
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 52 8e-07
gi|209969812 ankyrin repeat domain 25 [Homo sapiens] 52 8e-07
gi|31324547 ankyrin repeat domain 25 [Homo sapiens] 52 8e-07
gi|103471993 huntingtin interacting protein 14 [Homo sapiens] 52 1e-06
gi|166235148 osteoclast stimulating factor 1 [Homo sapiens] 51 2e-06
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi... 51 2e-06
gi|157504499 ankyrin repeat domain 47 [Homo sapiens] 50 3e-06
gi|12746412 ankyrin repeat, family A (RFXANK-like), 2 [Homo sapi... 50 4e-06
gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Hom... 48 2e-05
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom... 48 2e-05
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 48 2e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 48 2e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 48 2e-05
>gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens]
Length = 452
Score = 927 bits (2396), Expect = 0.0
Identities = 452/452 (100%), Positives = 452/452 (100%)
Query: 1 MKVQPSVTCVASWGGIVHLEAFGDPVIVLRGAWAVPRVDCLIDTLRTPNASCMRKGTHLL 60
MKVQPSVTCVASWGGIVHLEAFGDPVIVLRGAWAVPRVDCLIDTLRTPNASCMRKGTHLL
Sbjct: 1 MKVQPSVTCVASWGGIVHLEAFGDPVIVLRGAWAVPRVDCLIDTLRTPNASCMRKGTHLL 60
Query: 61 VPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVS 120
VPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVS
Sbjct: 61 VPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVS 120
Query: 121 PEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPL 180
PEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPL
Sbjct: 121 PEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPL 180
Query: 181 VSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTALEWAVLTDSFDTV 240
VSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTALEWAVLTDSFDTV
Sbjct: 181 VSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTALEWAVLTDSFDTV 240
Query: 241 WRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQ 300
WRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQ
Sbjct: 241 WRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQ 300
Query: 301 EGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPP 360
EGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPP
Sbjct: 301 EGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPP 360
Query: 361 GSPQRSPWVFVPYQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSP 420
GSPQRSPWVFVPYQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSP
Sbjct: 361 GSPQRSPWVFVPYQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSP 420
Query: 421 SGHQSLALPLWRYQELRIEKRKQEEEARMAQK 452
SGHQSLALPLWRYQELRIEKRKQEEEARMAQK
Sbjct: 421 SGHQSLALPLWRYQELRIEKRKQEEEARMAQK 452
>gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens]
Length = 272
Score = 419 bits (1076), Expect = e-117
Identities = 216/238 (90%), Positives = 217/238 (91%), Gaps = 11/238 (4%)
Query: 136 MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 195
MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER
Sbjct: 1 MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
Query: 196 RDQRGLTALMKAAMRNRC----------ADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 245
RDQRGLTALMKAAMRNRC ADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ
Sbjct: 61 RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
Query: 246 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 305
LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL
Sbjct: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180
Query: 306 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPL-VPQSPPGS 362
DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELL A P+S P S
Sbjct: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSS 238
>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 1006
Score = 231 bits (588), Expect = 1e-60
Identities = 165/451 (36%), Positives = 223/451 (49%), Gaps = 54/451 (11%)
Query: 41 LIDTLRTPNASCMRKGTHLLVPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALY 100
++++ R P AS P +EEE + + E +P ET T L
Sbjct: 554 ILESARHPQAS---HSDDSFYPFEDEEEHGVESAE-SVPEGVPESVPETAT-------LL 602
Query: 101 WACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQ 160
A N+ L+ ++ GVS EEA + D NGRTGL+VACYHGF V L+ CP +DVN
Sbjct: 603 RAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNW 662
Query: 161 QDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRC------- 213
QD G+TAL+ AAQAGH + + LLNY+ GLDLERR+ G TALMKAAM+ R
Sbjct: 663 QDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALM 722
Query: 214 ---ADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLV 270
AD+ A DP RG + EWA T D V +++LL RP EQ + Y+PE P
Sbjct: 723 LAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAA 782
Query: 271 AQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPD 330
+ L + + + L+ P++GGVLDH+V TTSL SP V C T+CP+
Sbjct: 783 RKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPE 842
Query: 331 HPPSLGTRSKSVPELL----------------GTAPPPPLVPQSPPGSPQRSPWVFVP-- 372
PPS+G R +V E+L G A Q S + SP +P
Sbjct: 843 SPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPA 902
Query: 373 -------YQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQP-----KPSP 420
+P+ LQ L+ R S P VP++ +SKA + + Q +
Sbjct: 903 LGSRGPAAPAPRKASLLPLQRLRRR-SVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKD 961
Query: 421 SGHQSLALPLWRYQELRIEKRKQEEEARMAQ 451
SGH L +P WRY+E + EKRK EE + Q
Sbjct: 962 SGH--LQIPKWRYKEAKEEKRKAEEAEKKRQ 990
>gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 494
Score = 229 bits (584), Expect = 4e-60
Identities = 161/430 (37%), Positives = 215/430 (50%), Gaps = 51/430 (11%)
Query: 62 PCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSP 121
P +EEE + + E +P ET T L A N+ L+ ++ GVS
Sbjct: 60 PFEDEEEHGVESAE-SVPEGVPESVPETAT-------LLRAACANNVGLLRTLVRRGVSV 111
Query: 122 EEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLV 181
EEA + D NGRTGL+VACYHGF V L+ CP +DVN QD G+TAL+ AAQAGH +
Sbjct: 112 EEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIIT 171
Query: 182 SLLLNYYVGLDLERRDQRGLTALMKAAMRNRC----------ADLTAVDPVRGKTALEWA 231
+ LLNY+ GLDLERR+ G TALMKAAM+ R AD+ A DP RG + EWA
Sbjct: 172 NYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWA 231
Query: 232 VLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATL 291
T D V +++LL RP EQ + Y+PE P + L + + + L
Sbjct: 232 TYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVL 291
Query: 292 SLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELL----- 346
+ P++GGVLDH+V TTSL SP V C T+CP+ PPS+G R +V E+L
Sbjct: 292 TPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAA 351
Query: 347 -----------GTAPPPPLVPQSPPGSPQRSPWVFVP---------YQSPQGILSKCLQW 386
G A Q S + SP +P +P+ LQ
Sbjct: 352 RGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQR 411
Query: 387 LQPRDSTSPRPQVPKILLSKASSSSHQCQP-----KPSPSGHQSLALPLWRYQELRIEKR 441
L+ R S P VP++ +SKA + + Q + SGH L +P WRY+E + EKR
Sbjct: 412 LRRR-SVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGH--LQIPKWRYKEAKEEKR 468
Query: 442 KQEEEARMAQ 451
K EE + Q
Sbjct: 469 KAEEAEKKRQ 478
>gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 494
Score = 229 bits (584), Expect = 4e-60
Identities = 161/430 (37%), Positives = 215/430 (50%), Gaps = 51/430 (11%)
Query: 62 PCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSP 121
P +EEE + + E +P ET T L A N+ L+ ++ GVS
Sbjct: 60 PFEDEEEHGVESAE-SVPEGVPESVPETAT-------LLRAACANNVGLLRTLVRRGVSV 111
Query: 122 EEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLV 181
EEA + D NGRTGL+VACYHGF V L+ CP +DVN QD G+TAL+ AAQAGH +
Sbjct: 112 EEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIIT 171
Query: 182 SLLLNYYVGLDLERRDQRGLTALMKAAMRNRC----------ADLTAVDPVRGKTALEWA 231
+ LLNY+ GLDLERR+ G TALMKAAM+ R AD+ A DP RG + EWA
Sbjct: 172 NYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWA 231
Query: 232 VLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATL 291
T D V +++LL RP EQ + Y+PE P + L + + + L
Sbjct: 232 TYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVL 291
Query: 292 SLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELL----- 346
+ P++GGVLDH+V TTSL SP V C T+CP+ PPS+G R +V E+L
Sbjct: 292 TPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAA 351
Query: 347 -----------GTAPPPPLVPQSPPGSPQRSPWVFVP---------YQSPQGILSKCLQW 386
G A Q S + SP +P +P+ LQ
Sbjct: 352 RGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQR 411
Query: 387 LQPRDSTSPRPQVPKILLSKASSSSHQCQP-----KPSPSGHQSLALPLWRYQELRIEKR 441
L+ R S P VP++ +SKA + + Q + SGH L +P WRY+E + EKR
Sbjct: 412 LRRR-SVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGH--LQIPKWRYKEAKEEKR 468
Query: 442 KQEEEARMAQ 451
K EE + Q
Sbjct: 469 KAEEAEKKRQ 478
>gi|169208819 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 57.8 bits (138), Expect = 2e-08
Identities = 93/375 (24%), Positives = 138/375 (36%), Gaps = 65/375 (17%)
Query: 48 PNASCMRKGTHLLVPCLEEEELALHRRRLDMSEA--LPCPGKETPTPGCRLGALYWACVH 105
P C R GT + ++ ++ L R LD + + C ++ TP L A
Sbjct: 4 PKDLCPRAGTRTFLEAMQAGKVHLARFVLDALDRSIIDCRAEQGRTP------LMVAVGL 57
Query: 106 NDPTQ----LQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQ 161
DP ++ +L+ G + D GRT L +AC G V LL D
Sbjct: 58 PDPALRARFVRLLLEQGAA---VNLRDERGRTALSLACERGHLDAVQLLVQFSG-DPEAA 113
Query: 162 DKGGDTALMLAAQAGHVPLVSLLLNYY--VGLDLERRDQRGLTALMKAAMRNRCADLTAV 219
D G++ +M AA GH ++ L+ + +GL L+R ++ GLTAL AA R + A+
Sbjct: 114 DSAGNSPVMWAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQAL 173
Query: 220 DPVRGKTALEWAVLTDSFDT-----VWRIRQLLRRPQVEQLSQHYKPEWPALSG------ 268
G+ A A + D+ RRP +L + + +G
Sbjct: 174 TGPWGRAAAAAAARGSNSDSPPGRPAPAASPEHRRPSPRRLPRPLLARFARAAGGHGGEA 233
Query: 269 -----LVAQAQAQAQVAPSL---------------LERLQATLSLPFAPSPQEGGVLDHL 308
+ +AQ P L RL+A + SPQ G
Sbjct: 234 GSAGKNSGRHRAQGSERPELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTGRWR 293
Query: 309 VTATTSLASPFVTTACHTLCPDHPPS------LGTRSKS----VPELLGTAPPPPLVPQ- 357
A P + A L P HP LG R +S +P L+G AP P P+
Sbjct: 294 SQEVLEGAPPTLAQAPIGLSP-HPEGGPGSGRLGLRRRSTAPDIPSLVGEAPGPESGPEL 352
Query: 358 ----SPPGSPQRSPW 368
P P +PW
Sbjct: 353 EANALPVSVPGPNPW 367
>gi|169208593 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 57.8 bits (138), Expect = 2e-08
Identities = 93/375 (24%), Positives = 138/375 (36%), Gaps = 65/375 (17%)
Query: 48 PNASCMRKGTHLLVPCLEEEELALHRRRLDMSEA--LPCPGKETPTPGCRLGALYWACVH 105
P C R GT + ++ ++ L R LD + + C ++ TP L A
Sbjct: 4 PKDLCPRAGTRTFLEAMQAGKVHLARFVLDALDRSIIDCRAEQGRTP------LMVAVGL 57
Query: 106 NDPTQ----LQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQ 161
DP ++ +L+ G + D GRT L +AC G V LL D
Sbjct: 58 PDPALRARFVRLLLEQGAA---VNLRDERGRTALSLACERGHLDAVQLLVQFSG-DPEAA 113
Query: 162 DKGGDTALMLAAQAGHVPLVSLLLNYY--VGLDLERRDQRGLTALMKAAMRNRCADLTAV 219
D G++ +M AA GH ++ L+ + +GL L+R ++ GLTAL AA R + A+
Sbjct: 114 DSAGNSPVMWAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQAL 173
Query: 220 DPVRGKTALEWAVLTDSFDT-----VWRIRQLLRRPQVEQLSQHYKPEWPALSG------ 268
G+ A A + D+ RRP +L + + +G
Sbjct: 174 TGPWGRAAAAAAARGSNSDSPPGRPAPAASPEHRRPSPRRLPRPLLARFARAAGGHGGEA 233
Query: 269 -----LVAQAQAQAQVAPSL---------------LERLQATLSLPFAPSPQEGGVLDHL 308
+ +AQ P L RL+A + SPQ G
Sbjct: 234 GSAGKNSGRHRAQGSERPELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTGRWR 293
Query: 309 VTATTSLASPFVTTACHTLCPDHPPS------LGTRSKS----VPELLGTAPPPPLVPQ- 357
A P + A L P HP LG R +S +P L+G AP P P+
Sbjct: 294 SQEVLEGAPPTLAQAPIGLSP-HPEGGPGSGRLGLRRRSTAPDIPSLVGEAPGPESGPEL 352
Query: 358 ----SPPGSPQRSPW 368
P P +PW
Sbjct: 353 EANALPVSVPGPNPW 367
>gi|169208169 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 56.2 bits (134), Expect = 6e-08
Identities = 92/375 (24%), Positives = 138/375 (36%), Gaps = 65/375 (17%)
Query: 48 PNASCMRKGTHLLVPCLEEEELALHRRRLDMSEA--LPCPGKETPTPGCRLGALYWACVH 105
P C R GT + ++ ++ L R LD + + C ++ TP L A
Sbjct: 4 PKDLCPRAGTRTFLEAMQAGKVHLARFVLDALDRSIIDCRAEQGRTP------LMVAVGL 57
Query: 106 NDPTQ----LQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQ 161
DP ++ +L+ G + D GRT L +AC G V LL D
Sbjct: 58 PDPALRARFVRLLLEQGAA---VNLRDERGRTALSLACERGHLDAVQLLVQFSG-DPEAA 113
Query: 162 DKGGDTALMLAAQAGHVPLVSLLLNYY--VGLDLERRDQRGLTALMKAAMRNRCADLTAV 219
D G++ +M AA GH ++ L+ + +GL L+R ++ GLTAL AA R + A+
Sbjct: 114 DSAGNSPVMWAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQAL 173
Query: 220 DPVRGKTALEWAVLTDSFDT-----VWRIRQLLRRPQVEQLSQHYKPEWPALSG------ 268
G+ A A + D+ RRP +L + + +G
Sbjct: 174 TGPWGRAAAAAAARGSNSDSPPGRPAPAASPEHRRPSPRRLPRPLLARFARAAGGHGGEA 233
Query: 269 -----LVAQAQAQAQVAPSL---------------LERLQATLSLPFAPSPQEGGVLDHL 308
+ +AQ P L RL+A + SPQ G
Sbjct: 234 GSAGKNSGRHRAQGSERPELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTGRWR 293
Query: 309 VTATTSLASPFVTTACHTLCPDHPPS------LGTRSKS----VPELLGTAPPPPLVPQS 358
A P + A L P HP LG R +S +P L+G AP P P+
Sbjct: 294 SQEVLEGAPPTLAQAPIGLSP-HPEGGPGSGRLGLRRRSTAPDIPSLVGEAPGPESGPEL 352
Query: 359 PPGS-----PQRSPW 368
+ P +PW
Sbjct: 353 EANALSVSVPGPNPW 367
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 55.1 bits (131), Expect = 1e-07
Identities = 40/98 (40%), Positives = 51/98 (52%), Gaps = 6/98 (6%)
Query: 111 LQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALM 170
++ +LD G S Q DSNGRT L A Y G VV LL D+ +D G T L
Sbjct: 528 IRTLLDNGAS---VNQCDSNGRTLLANAAYSGSLDVVNLLV-SRGADLEIEDAHGHTPLT 583
Query: 171 LAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAA 208
LAA+ GH +V+ L+ G ++ DQ G TAL AA
Sbjct: 584 LAARQGHTKVVNCLIG--CGANINHTDQDGWTALRSAA 619
Score = 53.5 bits (127), Expect = 4e-07
Identities = 47/137 (34%), Positives = 63/137 (45%), Gaps = 19/137 (13%)
Query: 111 LQAILDGGVSPEEATQVDSNGRTGLMVACY-----HGFQSVVALLSHCPFLDVNQQDKGG 165
++ +LD G E D +GRT L VA G SVV+LL +V+ DK G
Sbjct: 693 VEHLLDHGA---EVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRG-AEVDHCDKDG 748
Query: 166 DTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGK 225
T L++AA GHV +V LLL G D++ D G T L+ AA + +
Sbjct: 749 MTPLLVAAYEGHVDVVDLLLE--GGADVDHTDNNGRTPLLAAASMGHASVV--------N 798
Query: 226 TALEWAVLTDSFDTVWR 242
T L W DS D+ R
Sbjct: 799 TLLFWGAAVDSIDSEGR 815
Score = 52.4 bits (124), Expect = 8e-07
Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 6/110 (5%)
Query: 99 LYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDV 158
LY + N T + L+ G + E + D+ GRT L V+C+ G +V +L DV
Sbjct: 950 LYILALENQLTMAEYFLENGANVEAS---DAEGRTALHVSCWQGHMEMVQVLI-AYHADV 1005
Query: 159 NQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAA 208
N D +AL AA GHV +V LL+ + G ++ +G TAL AA
Sbjct: 1006 NAADNEKRSALQSAAWQGHVKVVQLLIEH--GAVVDHTCNQGATALCIAA 1053
Score = 48.1 bits (113), Expect = 2e-05
Identities = 37/100 (37%), Positives = 54/100 (54%), Gaps = 8/100 (8%)
Query: 111 LQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVA-LLSHCPFLDVNQQDKGGDTAL 169
+ A+L GV + A D++ RT L A + G + +V LL H +VN+ D G TAL
Sbjct: 627 VSALLYAGVKVDCA---DADSRTALRAAAWGGHEDIVLNLLQHGA--EVNKADNEGRTAL 681
Query: 170 MLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAM 209
+ AA GH +V LL++ G ++ D G TAL AA+
Sbjct: 682 IAAAYMGHREIVEHLLDH--GAEVNHEDVDGRTALSVAAL 719
Score = 45.8 bits (107), Expect = 8e-05
Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 123 EATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVS 182
E D +G T L+VA Y G VV LL DV+ D G T L+ AA GH +V+
Sbjct: 740 EVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGG-ADVDHTDNNGRTPLLAAASMGHASVVN 798
Query: 183 LLLNYYVGLDLERRDQRGLTALMKAA 208
LL + G ++ D G T L A+
Sbjct: 799 TLL--FWGAAVDSIDSEGRTVLSIAS 822
Score = 35.4 bits (80), Expect = 0.11
Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 129 SNGRTGLMVACYHGFQSVV-ALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNY 187
+ G T L +A G VV LL H D N D+ G TA+ +AA+ GH ++ LL Y
Sbjct: 1043 NQGATALCIAAQEGHIDVVQVLLEHGA--DPNHADQFGRTAMRVAAKNGHSQIIKLLEKY 1100
Score = 32.3 bits (72), Expect = 0.90
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 127 VDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGH 177
+DS GRT L +A G VV L LD N +D G T L +AA GH
Sbjct: 810 IDSEGRTVLSIASAQGNVEVVRTLLD-RGLDENHRDDAGWTPLHMAAFEGH 859
>gi|41327754 ankyrin repeat domain 3 [Homo sapiens]
Length = 784
Score = 52.8 bits (125), Expect = 6e-07
Identities = 39/113 (34%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 98 ALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLD 157
AL++A + D + + +L+ S E VD GRT + VAC HG +++V +L +D
Sbjct: 507 ALHFAAQNGDESSTRLLLEKNASVNE---VDFEGRTPMHVACQHGQENIVRILLR-RGVD 562
Query: 158 VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMR 210
V+ Q K L AA GH+P+V LL G+ + + G T L AA R
Sbjct: 563 VSLQGKDAWLPLHYAAWQGHLPIVKLLAK-QPGVSVNAQTLDGRTPLHLAAQR 614
Score = 32.3 bits (72), Expect = 0.90
Identities = 29/85 (34%), Positives = 36/85 (42%), Gaps = 3/85 (3%)
Query: 130 NGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYV 189
+GRT L +A G V +L DVN T L +AA+ GH LLL+
Sbjct: 603 DGRTPLHLAAQRGHYRVARILIDL-CSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGA 661
Query: 190 GLDLERRDQRGLTALMKAAMRNRCA 214
G + D G TAL AA A
Sbjct: 662 GKEAMTSD--GYTALHLAARNGHLA 684
>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
sapiens]
Length = 522
Score = 52.8 bits (125), Expect = 6e-07
Identities = 37/84 (44%), Positives = 48/84 (57%), Gaps = 7/84 (8%)
Query: 127 VDSNGRTGLMVACYHGFQSVVALL--SHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLL 184
VD GRT A HG + L S C D N +DK G+TAL LAA GH+ ++ L
Sbjct: 155 VDKLGRTAFHRAAEHGQLDALDFLVGSGC---DHNVKDKEGNTALHLAAGRGHMAVLQRL 211
Query: 185 LNYYVGLDLERRDQRGLTALMKAA 208
++ +GLDLE ++ GLTAL AA
Sbjct: 212 VD--IGLDLEEQNAEGLTALHSAA 233
Score = 45.8 bits (107), Expect = 8e-05
Identities = 27/87 (31%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
Query: 99 LYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDV 158
L+ A HN P ++ +++ S + VD+ +T L +A H +Q + +L +D+
Sbjct: 295 LHLAVRHNFPALVRLLIN---SDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG-VDL 350
Query: 159 NQQDKGGDTALMLAAQAGHVPLVSLLL 185
N +DK G TAL +A ++ HV LV +++
Sbjct: 351 NLRDKQGKTALAVAVRSNHVSLVDMII 377
Score = 45.4 bits (106), Expect = 1e-04
Identities = 37/116 (31%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 96 LGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPF 155
L L++A + + ++ G A VD G + L +A H F ++V LL +
Sbjct: 259 LSCLHYAALSGSEDVSRVLIHAGGC---ANVVDHQGASPLHLAVRHNFPALVRLLINSDS 315
Query: 156 LDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRN 211
DVN D T L LAA+ + +LL G+DL RD++G TAL A N
Sbjct: 316 -DVNAVDNRQQTPLHLAAEHAWQDIADMLL--IAGVDLNLRDKQGKTALAVAVRSN 368
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 8/118 (6%)
Query: 98 ALYWACVHNDPTQLQAILDGGVSPEEATQVDSN-------GRTGLMVACYHGFQSVVALL 150
AL+WA ++ +L+ + +E V + G L+++ + G ++ +L
Sbjct: 51 ALHWAAGAGHEQAVRLLLEHEAAVDEEDAVGALTEARLCFGMNALLLSAWFGHLRILQIL 110
Query: 151 SHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAA 208
+ ++ + K G T L AAQ GHVP+++ ++ + L+ D+ G TA +AA
Sbjct: 111 VNSG-AKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAA 167
Score = 34.3 bits (77), Expect = 0.24
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNY 187
D G T L +A G +V+ L LD+ +Q+ G TAL AA H V LLL
Sbjct: 189 DKEGNTALHLAAGRGHMAVLQRLVDIG-LDLEEQNAEGLTALHSAAGGSHPDCVQLLLR- 246
Query: 188 YVGLDLERRDQRGLTALMKAAM 209
G + Q+ L+ L AA+
Sbjct: 247 -AGSTVNALTQKNLSCLHYAAL 267
>gi|70995267 ankyrin repeat domain 29 [Homo sapiens]
Length = 301
Score = 52.8 bits (125), Expect = 6e-07
Identities = 44/122 (36%), Positives = 58/122 (47%), Gaps = 9/122 (7%)
Query: 87 KETPTPGCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSV 146
KETP A +WA + L+ +L+ G + DS+G T LMVA Y G
Sbjct: 8 KETPLAN----AAFWAARRGNLALLKLLLNSGRVDVDCR--DSHGTTLLMVAAYAGHIDC 61
Query: 147 VALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMK 206
V L D+N Q + G TAL AAQ GH +V L + G E R + G TAL+
Sbjct: 62 VRELV-LQGADINLQRESGTTALFFAAQQGHNDVVRFLFGF--GASTEFRTKDGGTALLA 118
Query: 207 AA 208
A+
Sbjct: 119 AS 120
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/119 (32%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 130 NGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYV 189
+G T L +A G+ V+ LL VNQ + G L +A+Q GH +V ++L
Sbjct: 144 DGATALFLAAQGGYLDVIRLLL-ASGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGA 202
Query: 190 GLDLERRDQRGLTALMKAAMR---NRCADLTAVDPV-----RGKTALEWAVLTDSFDTV 240
D R D G TAL+KAA + + +L P G +AL AVL+ + TV
Sbjct: 203 DRDAARND--GTTALLKAANKGYNDVIKELLKFSPTLGILKNGTSALHAAVLSGNIKTV 259
Score = 39.3 bits (90), Expect = 0.007
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 6/101 (5%)
Query: 98 ALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVV-ALLSHCPFL 156
AL++A ++ + G S E T+ +G T L+ A +G VV LL H
Sbjct: 82 ALFFAAQQGHNDVVRFLFGFGASTEFRTK---DGGTALLAASQYGHMQVVETLLKHGA-- 136
Query: 157 DVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRD 197
+++ Q G TAL LAAQ G++ ++ LLL ++ R+D
Sbjct: 137 NIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQD 177
Score = 38.9 bits (89), Expect = 0.010
Identities = 26/73 (35%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
Query: 138 ACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRD 197
A G +++ LL + +DV+ +D G T LM+AA AGH+ V L+ G D+ +
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELV--LQGADINLQR 76
Query: 198 QRGLTALMKAAMR 210
+ G TAL AA +
Sbjct: 77 ESGTTALFFAAQQ 89
Score = 29.3 bits (64), Expect = 7.7
Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 129 SNGRTGLMVACYHGFQSVVA-LLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLL 185
++G T L+ A G+ V+ LL P L + K G +AL A +G++ V+LLL
Sbjct: 209 NDGTTALLKAANKGYNDVIKELLKFSPTLGIL---KNGTSALHAAVLSGNIKTVALLL 263
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 16/124 (12%)
Query: 124 ATQVDSNGRTGLMVACYHG-FQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVS 182
A VDS+G+T L A G Q+V L H +N +D G+ L+LA Q GH +
Sbjct: 115 AESVDSSGKTALHYAAAQGCLQAVQILCEHKS--PINLKDLDGNIPLLLAVQNGHSEICH 172
Query: 183 LLLNYYVGLDLERRDQRGLTALMKA----------AMRNRCADLTAVDPVRGKTALEWAV 232
LL++ G D+ R++ G TALM A A+ + ADL VD + G AL ++
Sbjct: 173 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSL-GYNALHYSK 229
Query: 233 LTDS 236
L+++
Sbjct: 230 LSEN 233
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 21/113 (18%)
Query: 93 GCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVA-LLS 151
GC L A+ C H P L+ D +G L++A +G + LL
Sbjct: 133 GC-LQAVQILCEHKSPINLK---------------DLDGNIPLLLAVQNGHSEICHFLLD 176
Query: 152 HCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 204
H DVN ++K G TALMLA + G V L+ G DL D G AL
Sbjct: 177 HGA--DVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 225
Score = 35.0 bits (79), Expect = 0.14
Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 15/108 (13%)
Query: 135 LMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLE 194
L+ A +G VA L + D G TA LAA GHV + +++ + G+D+
Sbjct: 26 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 83
Query: 195 RRDQRGLTALMKAA-----------MRNRCADLTAVDPVRGKTALEWA 231
+D G +AL AA ++++C +VD GKTAL +A
Sbjct: 84 AQDTTGHSALHLAAKNSHHECIRKLLQSKC-PAESVDS-SGKTALHYA 129
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 16/124 (12%)
Query: 124 ATQVDSNGRTGLMVACYHG-FQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVS 182
A VDS+G+T L A G Q+V L H +N +D G+ L+LA Q GH +
Sbjct: 104 AESVDSSGKTALHYAAAQGCLQAVQILCEHKS--PINLKDLDGNIPLLLAVQNGHSEICH 161
Query: 183 LLLNYYVGLDLERRDQRGLTALMKA----------AMRNRCADLTAVDPVRGKTALEWAV 232
LL++ G D+ R++ G TALM A A+ + ADL VD + G AL ++
Sbjct: 162 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSL-GYNALHYSK 218
Query: 233 LTDS 236
L+++
Sbjct: 219 LSEN 222
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 21/113 (18%)
Query: 93 GCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVA-LLS 151
GC L A+ C H P L+ D +G L++A +G + LL
Sbjct: 122 GC-LQAVQILCEHKSPINLK---------------DLDGNIPLLLAVQNGHSEICHFLLD 165
Query: 152 HCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 204
H DVN ++K G TALMLA + G V L+ G DL D G AL
Sbjct: 166 HGA--DVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 214
Score = 35.0 bits (79), Expect = 0.14
Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 15/108 (13%)
Query: 135 LMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLE 194
L+ A +G VA L + D G TA LAA GHV + +++ + G+D+
Sbjct: 15 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 72
Query: 195 RRDQRGLTALMKAA-----------MRNRCADLTAVDPVRGKTALEWA 231
+D G +AL AA ++++C +VD GKTAL +A
Sbjct: 73 AQDTTGHSALHLAAKNSHHECIRKLLQSKC-PAESVDS-SGKTALHYA 118
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 16/124 (12%)
Query: 124 ATQVDSNGRTGLMVACYHG-FQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVS 182
A VDS+G+T L A G Q+V L H +N +D G+ L+LA Q GH +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQILCEHKS--PINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 183 LLLNYYVGLDLERRDQRGLTALMKA----------AMRNRCADLTAVDPVRGKTALEWAV 232
LL++ G D+ R++ G TALM A A+ + ADL VD + G AL ++
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSL-GYNALHYSK 226
Query: 233 LTDS 236
L+++
Sbjct: 227 LSEN 230
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 21/113 (18%)
Query: 93 GCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVA-LLS 151
GC L A+ C H P L+ D +G L++A +G + LL
Sbjct: 130 GC-LQAVQILCEHKSPINLK---------------DLDGNIPLLLAVQNGHSEICHFLLD 173
Query: 152 HCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 204
H DVN ++K G TALMLA + G V L+ G DL D G AL
Sbjct: 174 HGA--DVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 222
Score = 35.0 bits (79), Expect = 0.14
Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 15/108 (13%)
Query: 135 LMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLE 194
L+ A +G VA L + D G TA LAA GHV + +++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 195 RRDQRGLTALMKAA-----------MRNRCADLTAVDPVRGKTALEWA 231
+D G +AL AA ++++C +VD GKTAL +A
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKC-PAESVDS-SGKTALHYA 126
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 16/124 (12%)
Query: 124 ATQVDSNGRTGLMVACYHG-FQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVS 182
A VDS+G+T L A G Q+V L H +N +D G+ L+LA Q GH +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQILCEHKS--PINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 183 LLLNYYVGLDLERRDQRGLTALMKA----------AMRNRCADLTAVDPVRGKTALEWAV 232
LL++ G D+ R++ G TALM A A+ + ADL VD + G AL ++
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSL-GYNALHYSK 226
Query: 233 LTDS 236
L+++
Sbjct: 227 LSEN 230
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 21/113 (18%)
Query: 93 GCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVA-LLS 151
GC L A+ C H P L+ D +G L++A +G + LL
Sbjct: 130 GC-LQAVQILCEHKSPINLK---------------DLDGNIPLLLAVQNGHSEICHFLLD 173
Query: 152 HCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 204
H DVN ++K G TALMLA + G V L+ G DL D G AL
Sbjct: 174 HGA--DVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 222
Score = 35.0 bits (79), Expect = 0.14
Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 15/108 (13%)
Query: 135 LMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLE 194
L+ A +G VA L + D G TA LAA GHV + +++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 195 RRDQRGLTALMKAA-----------MRNRCADLTAVDPVRGKTALEWA 231
+D G +AL AA ++++C +VD GKTAL +A
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKC-PAESVDS-SGKTALHYA 126
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 16/124 (12%)
Query: 124 ATQVDSNGRTGLMVACYHG-FQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVS 182
A VDS+G+T L A G Q+V L H +N +D G+ L+LA Q GH +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQILCEHKS--PINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 183 LLLNYYVGLDLERRDQRGLTALMKA----------AMRNRCADLTAVDPVRGKTALEWAV 232
LL++ G D+ R++ G TALM A A+ + ADL VD + G AL ++
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSL-GYNALHYSK 226
Query: 233 LTDS 236
L+++
Sbjct: 227 LSEN 230
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 21/113 (18%)
Query: 93 GCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVA-LLS 151
GC L A+ C H P L+ D +G L++A +G + LL
Sbjct: 130 GC-LQAVQILCEHKSPINLK---------------DLDGNIPLLLAVQNGHSEICHFLLD 173
Query: 152 HCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 204
H DVN ++K G TALMLA + G V L+ G DL D G AL
Sbjct: 174 HGA--DVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 222
Score = 35.0 bits (79), Expect = 0.14
Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 15/108 (13%)
Query: 135 LMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLE 194
L+ A +G VA L + D G TA LAA GHV + +++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 195 RRDQRGLTALMKAA-----------MRNRCADLTAVDPVRGKTALEWA 231
+D G +AL AA ++++C +VD GKTAL +A
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKC-PAESVDS-SGKTALHYA 126
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 16/124 (12%)
Query: 124 ATQVDSNGRTGLMVACYHG-FQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVS 182
A VDS+G+T L A G Q+V L H +N +D G+ L+LA Q GH +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQILCEHKS--PINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 183 LLLNYYVGLDLERRDQRGLTALMKA----------AMRNRCADLTAVDPVRGKTALEWAV 232
LL++ G D+ R++ G TALM A A+ + ADL VD + G AL ++
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSL-GYNALHYSK 226
Query: 233 LTDS 236
L+++
Sbjct: 227 LSEN 230
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 21/113 (18%)
Query: 93 GCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVA-LLS 151
GC L A+ C H P L+ D +G L++A +G + LL
Sbjct: 130 GC-LQAVQILCEHKSPINLK---------------DLDGNIPLLLAVQNGHSEICHFLLD 173
Query: 152 HCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 204
H DVN ++K G TALMLA + G V L+ G DL D G AL
Sbjct: 174 HGA--DVNSRNKSGRTALMLACEIGSSNAVEALIK--KGADLNLVDSLGYNAL 222
Score = 35.0 bits (79), Expect = 0.14
Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 15/108 (13%)
Query: 135 LMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLE 194
L+ A +G VA L + D G TA LAA GHV + +++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 195 RRDQRGLTALMKAA-----------MRNRCADLTAVDPVRGKTALEWA 231
+D G +AL AA ++++C +VD GKTAL +A
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKC-PAESVDS-SGKTALHYA 126
>gi|209969812 ankyrin repeat domain 25 [Homo sapiens]
Length = 851
Score = 52.4 bits (124), Expect = 8e-07
Identities = 35/77 (45%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 131 GRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVG 190
G+T LM+A HG VV L C DVN QD G TALM A + GH + LLL
Sbjct: 739 GQTALMLAVSHGRVDVVKALLACE-ADVNVQDDDGSTALMCACEHGHKEIAGLLL-AVPS 796
Query: 191 LDLERRDQRGLTALMKA 207
D+ D+ G TALM A
Sbjct: 797 CDISLTDRDGSTALMVA 813
Score = 51.2 bits (121), Expect = 2e-06
Identities = 24/57 (42%), Positives = 33/57 (57%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLL 184
D +G T LM AC HG + + LL P D++ D+ G TALM+A AG + S+L
Sbjct: 769 DDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASML 825
Score = 33.5 bits (75), Expect = 0.41
Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQA---GHVPLVSLL 184
DSNG T L + H VV L V++Q++ G + +ML A A + ++L
Sbjct: 664 DSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVL 723
Query: 185 LNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTALE 229
+ +G + Q G TALM A R VD V+ A E
Sbjct: 724 QLFRLGNINAKASQAGQTALMLAVSHGR------VDVVKALLACE 762
>gi|31324547 ankyrin repeat domain 25 [Homo sapiens]
Length = 851
Score = 52.4 bits (124), Expect = 8e-07
Identities = 35/77 (45%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 131 GRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVG 190
G+T LM+A HG VV L C DVN QD G TALM A + GH + LLL
Sbjct: 739 GQTALMLAVSHGRVDVVKALLACE-ADVNVQDDDGSTALMCACEHGHKEIAGLLL-AVPS 796
Query: 191 LDLERRDQRGLTALMKA 207
D+ D+ G TALM A
Sbjct: 797 CDISLTDRDGSTALMVA 813
Score = 51.2 bits (121), Expect = 2e-06
Identities = 24/57 (42%), Positives = 33/57 (57%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLL 184
D +G T LM AC HG + + LL P D++ D+ G TALM+A AG + S+L
Sbjct: 769 DDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASML 825
Score = 33.5 bits (75), Expect = 0.41
Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQA---GHVPLVSLL 184
DSNG T L + H VV L V++Q++ G + +ML A A + ++L
Sbjct: 664 DSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVL 723
Query: 185 LNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTALE 229
+ +G + Q G TALM A R VD V+ A E
Sbjct: 724 QLFRLGNINAKASQAGQTALMLAVSHGR------VDVVKALLACE 762
>gi|103471993 huntingtin interacting protein 14 [Homo sapiens]
Length = 632
Score = 51.6 bits (122), Expect = 1e-06
Identities = 62/224 (27%), Positives = 93/224 (41%), Gaps = 31/224 (13%)
Query: 85 PGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQ 144
P KE T L+WA ++N ++ + G ++ D N T L A G
Sbjct: 86 PDKENVT------LLHWAAINNRIDLVKYYISKGAIVDQLGG-DLNS-TPLHWATRQGHL 137
Query: 145 SVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 204
S+V L D + D G + + LAAQ GH +V+ L+ G D++ DQ G+T L
Sbjct: 138 SMVVQLMKYG-ADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK--GQDVDMMDQNGMTPL 194
Query: 205 MKAAMRNRCADLTAV-----------DPVRGKTALEWAVLTDSFDTVWRI--------RQ 245
M AA R D T + D TAL WAVL + + + Q
Sbjct: 195 MWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQ 254
Query: 246 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQA 289
++ L++ K W ++ L QA+ PS L +L+A
Sbjct: 255 NIKGESALDLAKQRKNVW-MINHLQEARQAKGYDNPSFLRKLKA 297
>gi|166235148 osteoclast stimulating factor 1 [Homo sapiens]
Length = 214
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 3/101 (2%)
Query: 99 LYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDV 158
L+ A + + L+ LD V +D G T L AC+ G + +V +L P +++
Sbjct: 77 LHEAAKRGNLSWLRECLDNRVG---VNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIEL 133
Query: 159 NQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQR 199
NQQ+K GDTAL AA G+ +V LLL DL +++
Sbjct: 134 NQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKK 174
>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
sapiens]
Length = 1771
Score = 50.8 bits (120), Expect = 2e-06
Identities = 54/163 (33%), Positives = 76/163 (46%), Gaps = 31/163 (19%)
Query: 84 CPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGF 143
C K TP L WA ++ +L G + Q +N T L+VA G+
Sbjct: 165 CSDKYGTTP------LVWAARKGHLECVKHLLAMGA---DVDQEGANSMTALIVAVKGGY 215
Query: 144 -QSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLT 202
QSV +L P +VN DK G+TALM+A++ GH +V LL+ G + D+ G T
Sbjct: 216 TQSVKEILKRNP--NVNLTDKDGNTALMIASKEGHTEIVQDLLD--AGTYVNIPDRSGDT 271
Query: 203 ALMKA----------AMRNRCADLTAVDPVRG---KTALEWAV 232
L+ A A+ + AD+ +RG KTAL WAV
Sbjct: 272 VLIGAVRGGHVEIVRALLQKYADI----DIRGQDNKTALYWAV 310
Score = 39.7 bits (91), Expect = 0.006
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 13/130 (10%)
Query: 148 ALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKA 207
ALL C DV+++++ G T LM+AA+ G++ +V L+ +LE D TAL+ A
Sbjct: 23 ALLEKCK--DVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLE--DLDNWTALISA 78
Query: 208 AMRN---------RCADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQH 258
+ +C + G TAL WA D V + P V L
Sbjct: 79 SKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSV 138
Query: 259 YKPEWPALSG 268
Y W A G
Sbjct: 139 YPIIWAAGRG 148
Score = 38.5 bits (88), Expect = 0.013
Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 18/116 (15%)
Query: 98 ALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGL------MVACYHGFQSVVALLS 151
AL WAC ++ +L G +P TGL + A G +V LL
Sbjct: 107 ALMWACYKGRTDVVELLLSHGANPSV---------TGLYSVYPIIWAAGRGHADIVHLLL 157
Query: 152 HCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKA 207
VN DK G T L+ AA+ GH+ V LL +G D+++ +TAL+ A
Sbjct: 158 QNG-AKVNCSDKYGTTPLVWAARKGHLECVKHLL--AMGADVDQEGANSMTALIVA 210
Score = 32.7 bits (73), Expect = 0.69
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 10/132 (7%)
Query: 54 RKGTHLLVPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQA 113
R G +L+ + + + R L + G++ T ALYWA + T ++
Sbjct: 267 RSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKT------ALYWAVEKGNATMVRD 320
Query: 114 ILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAA 173
IL E T+ +G T L+ A VV LL V+ DK GDT L +A
Sbjct: 321 ILQCNPDTEICTK---DGETPLIKATKMRNIEVVELLLD-KGAKVSAVDKKGDTPLHIAI 376
Query: 174 QAGHVPLVSLLL 185
+ L LLL
Sbjct: 377 RGRSRKLAELLL 388
>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
Length = 821
Score = 50.4 bits (119), Expect = 3e-06
Identities = 34/79 (43%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 126 QVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLL 185
+ G+T LM+A HG Q +VA L C DVN QD G TALM A++ G + V LLL
Sbjct: 691 KASQTGQTALMLAISHGRQDMVATLLACG-ADVNAQDADGATALMCASEYGRLDTVRLLL 749
Query: 186 NYYVGLDLERRDQRGLTAL 204
G D D G +AL
Sbjct: 750 T-QPGCDPAILDNEGTSAL 767
Score = 42.7 bits (99), Expect = 7e-04
Identities = 47/139 (33%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAA------QAGHVPLV 181
D NG T L + HG ++ +LL +VN+Q++ G +ALMLAA + + +V
Sbjct: 620 DGNGNTALHYSVSHGNLAIASLLLDTGACEVNRQNRAGYSALMLAALTSVRQEEEDMAVV 679
Query: 182 SLLLNYYVGLDLERRDQRGLTALMKAAMRNR---------C-ADLTAVDPVRGKTALEWA 231
L + +G + Q G TALM A R C AD+ A D G TAL A
Sbjct: 680 QRL--FCMGDVNAKASQTGQTALMLAISHGRQDMVATLLACGADVNAQD-ADGATALMCA 736
Query: 232 VLTDSFDTVWRIRQLLRRP 250
DTV R LL +P
Sbjct: 737 SEYGRLDTV---RLLLTQP 752
Score = 32.7 bits (73), Expect = 0.69
Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 5/61 (8%)
Query: 149 LLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAA 208
LL+H VN D G+TAL + G++ + SLLL+ ++ R+++ G +ALM AA
Sbjct: 611 LLAHV----VNLADGNGNTALHYSVSHGNLAIASLLLD-TGACEVNRQNRAGYSALMLAA 665
Query: 209 M 209
+
Sbjct: 666 L 666
>gi|12746412 ankyrin repeat, family A (RFXANK-like), 2 [Homo
sapiens]
Length = 313
Score = 50.1 bits (118), Expect = 4e-06
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 57 THLLVPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILD 116
T LL L +LA L ++ + T L WA H ++ +L
Sbjct: 144 TPLLANSLSVHQLAAQGEMLYLATRIEQENVINHTDEEGFTPLMWAAAHGQIAVVEFLLQ 203
Query: 117 GGVSPEEATQVDSNGR-TGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQA 175
G P Q+ GR + L +AC G+ +V +L C +DVN+ D G T L+ A
Sbjct: 204 NGADP----QLLGKGRESALSLACSKGYTDIVKMLLDCG-VDVNEYDWNGGTPLLYAVHG 258
Query: 176 GHVPLVSLLL 185
HV V +LL
Sbjct: 259 NHVKCVKMLL 268
>gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Homo
sapiens]
Length = 1194
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/74 (45%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Query: 131 GRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVG 190
G+T LM+A HG +V L C DVN QD G TALM A++ GHV +V LLL G
Sbjct: 1076 GQTALMLAVSHGRIDMVKGLLACG-ADVNIQDDEGSTALMCASEHGHVEIVKLLL-AQPG 1133
Query: 191 LDLERRDQRGLTAL 204
+ D G TAL
Sbjct: 1134 CNGHLEDNDGSTAL 1147
Score = 42.4 bits (98), Expect = 9e-04
Identities = 23/57 (40%), Positives = 30/57 (52%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLL 184
D G T LM A HG +V LL P + + +D G TAL +A +AGH + LL
Sbjct: 1106 DDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1162
Score = 36.6 bits (83), Expect = 0.048
Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAG-----HVPLVS 182
D NG T L + H +V LL +V+ Q+K G T +MLAA A + +V
Sbjct: 1001 DGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDMRIVE 1060
Query: 183 LLLNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTA 227
L + G + Q G TALM A R +D V+G A
Sbjct: 1061 EL--FGCGDVNAKASQAGQTALMLAVSHGR------IDMVKGLLA 1097
Score = 31.2 bits (69), Expect = 2.0
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 15/97 (15%)
Query: 158 VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRN------ 211
+N D G+TAL + + +V LLL+ V +++ +++ G T +M AA+
Sbjct: 997 INLADGNGNTALHYSVSHSNFEIVKLLLDADV-CNVDHQNKAGYTPIMLAALAAVEAEKD 1055
Query: 212 --------RCADLTAVDPVRGKTALEWAVLTDSFDTV 240
C D+ A G+TAL AV D V
Sbjct: 1056 MRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMV 1092
>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
sapiens]
Length = 1352
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/74 (45%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Query: 131 GRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVG 190
G+T LM+A HG +V L C DVN QD G TALM A++ GHV +V LLL G
Sbjct: 1234 GQTALMLAVSHGRIDMVKGLLACG-ADVNIQDDEGSTALMCASEHGHVEIVKLLL-AQPG 1291
Query: 191 LDLERRDQRGLTAL 204
+ D G TAL
Sbjct: 1292 CNGHLEDNDGSTAL 1305
Score = 42.4 bits (98), Expect = 9e-04
Identities = 23/57 (40%), Positives = 30/57 (52%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLL 184
D G T LM A HG +V LL P + + +D G TAL +A +AGH + LL
Sbjct: 1264 DDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1320
Score = 36.6 bits (83), Expect = 0.048
Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Query: 128 DSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAG-----HVPLVS 182
D NG T L + H +V LL +V+ Q+K G T +MLAA A + +V
Sbjct: 1159 DGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDMRIVE 1218
Query: 183 LLLNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTA 227
L + G + Q G TALM A R +D V+G A
Sbjct: 1219 EL--FGCGDVNAKASQAGQTALMLAVSHGR------IDMVKGLLA 1255
Score = 31.2 bits (69), Expect = 2.0
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 15/97 (15%)
Query: 158 VNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRN------ 211
+N D G+TAL + + +V LLL+ V +++ +++ G T +M AA+
Sbjct: 1155 INLADGNGNTALHYSVSHSNFEIVKLLLDADV-CNVDHQNKAGYTPIMLAALAAVEAEKD 1213
Query: 212 --------RCADLTAVDPVRGKTALEWAVLTDSFDTV 240
C D+ A G+TAL AV D V
Sbjct: 1214 MRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMV 1250
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 48.1 bits (113), Expect = 2e-05
Identities = 37/99 (37%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Query: 106 NDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGG 165
ND +Q +L+ G P A D GRT L A +G +V LL D NQ+D G
Sbjct: 121 NDVETVQQLLEDGADPCAA---DDKGRTALHFASCNGNDQIVQLLLDHG-ADPNQRDGLG 176
Query: 166 DTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTAL 204
+T L LAA HVP+++ LL G ++ D+ G T L
Sbjct: 177 NTPLHLAACTNHVPVITTLLR--GGARVDALDRAGRTPL 213
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/174 (32%), Positives = 71/174 (40%), Gaps = 26/174 (14%)
Query: 264 PALSGLVAQAQAQAQVAPSL-LERLQATLSLPFAP--------SPQEGGVLD-HLVTATT 313
P LS L A Q P+L L LQA S P +P SPQ L HL+ A
Sbjct: 384 PPLSPL---ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440
Query: 314 S------LASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPPGSPQRSP 367
S + +PF A + P P S++ P L A PP VP SPP SP SP
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPP----SQAPPSL---AAPPLQVPPSPPASPPMSP 493
Query: 368 WVFVPYQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSPS 421
P Q+P + + LQ +P P P + + +S Q SPS
Sbjct: 494 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 547
Score = 42.7 bits (99), Expect = 7e-04
Identities = 54/174 (31%), Positives = 62/174 (35%), Gaps = 20/174 (11%)
Query: 261 PEWPALSGLVAQAQAQAQVAP---SLLERLQATLSLPFAPSPQEGGVLDHLVTATTSLAS 317
P P S L Q +AP S LQ S P P Q ATTSL S
Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ----------ATTSLGS 371
Query: 318 PFVTTACHTLCPDHPPS-LGTRSKSVPELLGTAPPPPLVPQSPPGSPQRSPWVFVPYQSP 376
P + A H+ P P S L T P L PPL Q+PP P P + SP
Sbjct: 372 PTLQ-ATHSFLPSPPLSPLATPPPQAPPALAL---PPL--QAPPSPPASPPLSPLATPSP 425
Query: 377 QGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSPSGHQSLALPL 430
Q + + LQ S P P V AS PS + A PL
Sbjct: 426 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 479
Score = 34.7 bits (78), Expect = 0.18
Identities = 43/146 (29%), Positives = 54/146 (36%), Gaps = 21/146 (14%)
Query: 264 PALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVLDHLVT----ATTSLASPF 319
PA + A +Q PSL A L PSP + T A LA+P
Sbjct: 455 PASPPVSPSATPPSQAPPSL-----AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 320 VTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPPGSPQ----RSPWVFVPYQS 375
+ A P PP+L T P L PP P P SP SP P Q+
Sbjct: 510 LQLAKPP--PQAPPALAT-----PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562
Query: 376 PQGILSKCLQWLQPRDSTSPRPQVPK 401
P + + LQ + P SP Q P+
Sbjct: 563 PPVLAAPLLQ-VPPSPPASPTLQAPR 587
Score = 34.3 bits (77), Expect = 0.24
Identities = 57/200 (28%), Positives = 67/200 (33%), Gaps = 55/200 (27%)
Query: 245 QLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGV 304
Q LR PQV + K PAL L + A +PS + QA +LP P
Sbjct: 278 QALRPPQV---TPPRKDAAPALGPL--SSSPLATPSPSAALQSQAPPTLPATP------- 325
Query: 305 LDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPP---- 360
H + T LA+P P PPS S P L T P PP P S
Sbjct: 326 --HSSSLTCQLATPL---------PLAPPS-----PSAPPSLQTLPSPPATPPSQATTSL 369
Query: 361 ------------GSPQRSPWVFVPYQSPQGILSKCLQWLQPRDSTS--------PRPQVP 400
SP SP P Q+P + LQ P S P PQ P
Sbjct: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ-APPSPPASPPLSPLATPSPQAP 428
Query: 401 KILLSKASSSSHQCQPKPSP 420
L + P PSP
Sbjct: 429 NALAVHLLQAPF--SPPPSP 446
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 47.8 bits (112), Expect = 2e-05
Identities = 59/188 (31%), Positives = 69/188 (36%), Gaps = 18/188 (9%)
Query: 245 QLLRRPQVEQLSQHYKPEW-PALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGG 303
Q LR PQV + P P S +A A +PS LQ S P P Q
Sbjct: 269 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ--- 325
Query: 304 VLDHLVTATTSLASPFVTTACHTLCPDHPPS-LGTRSKSVPELLGTAPPPPLVPQSPPGS 362
ATTSL SP + A H+ P P S L T P L PPL Q+PP
Sbjct: 326 -------ATTSLGSPTLQ-ATHSFLPSPPLSPLATPPPQAPPALAL---PPL--QAPPSP 372
Query: 363 PQRSPWVFVPYQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSPSG 422
P P + SPQ + + LQ S P P V AS PS +
Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432
Query: 423 HQSLALPL 430
A PL
Sbjct: 433 PSLAAPPL 440
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/174 (32%), Positives = 71/174 (40%), Gaps = 26/174 (14%)
Query: 264 PALSGLVAQAQAQAQVAPSL-LERLQATLSLPFAP--------SPQEGGVLD-HLVTATT 313
P LS L A Q P+L L LQA S P +P SPQ L HL+ A
Sbjct: 345 PPLSPL---ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401
Query: 314 S------LASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPPGSPQRSP 367
S + +PF A + P P S++ P L A PP VP SPP SP SP
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPP----SQAPPSL---AAPPLQVPPSPPASPPMSP 454
Query: 368 WVFVPYQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSPS 421
P Q+P + + LQ +P P P + + +S Q SPS
Sbjct: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508
Score = 34.7 bits (78), Expect = 0.18
Identities = 43/146 (29%), Positives = 54/146 (36%), Gaps = 21/146 (14%)
Query: 264 PALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVLDHLVT----ATTSLASPF 319
PA + A +Q PSL A L PSP + T A LA+P
Sbjct: 416 PASPPVSPSATPPSQAPPSL-----AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 470
Query: 320 VTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPPGSPQ----RSPWVFVPYQS 375
+ A P PP+L T P L PP P P SP SP P Q+
Sbjct: 471 LQLAKPP--PQAPPALAT-----PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 523
Query: 376 PQGILSKCLQWLQPRDSTSPRPQVPK 401
P + + LQ + P SP Q P+
Sbjct: 524 PPVLAAPLLQ-VPPSPPASPTLQAPR 548
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,899,084
Number of Sequences: 37866
Number of extensions: 1166952
Number of successful extensions: 9571
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 462
Number of HSP's that attempted gapping in prelim test: 6932
Number of HSP's gapped (non-prelim): 2304
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.