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Search of human proteins with 194018546
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194018546 PRAME family member 10 [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194018546 PRAME family member 10 [Homo sapiens] 971 0.0
gi|157426839 PRAME family member 17 [Homo sapiens] 844 0.0
gi|113865933 PRAME family member 16 [Homo sapiens] 842 0.0
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 827 0.0
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 827 0.0
gi|154800493 PRAME family member 22 [Homo sapiens] 585 e-167
gi|194306638 PRAME family member 3 [Homo sapiens] 579 e-165
gi|153791443 PRAME family member 18 [Homo sapiens] 577 e-165
gi|194306635 PRAME family member 19 [Homo sapiens] 574 e-164
gi|12738831 PRAME family member 1 [Homo sapiens] 555 e-158
gi|66954681 PRAME family member 13 [Homo sapiens] 547 e-156
gi|12738834 PRAME family member 2 [Homo sapiens] 531 e-151
gi|153792140 PRAME family member 14 [Homo sapiens] 508 e-144
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 504 e-143
gi|124249372 PRAME family member 12 [Homo sapiens] 460 e-129
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 446 e-125
gi|59676587 PRAME family member 8 [Homo sapiens] 446 e-125
gi|59676593 PRAME family member 7 [Homo sapiens] 443 e-124
gi|153792112 PRAME family member 20 [Homo sapiens] 424 e-119
gi|153945800 PRAME family member 21 [Homo sapiens] 424 e-119
gi|148356236 PRAME family member 15 [Homo sapiens] 408 e-114
gi|61102721 PRAME family member 9 [Homo sapiens] 408 e-114
gi|61696142 PRAME family member 5 [Homo sapiens] 405 e-113
gi|58219004 PRAME family member 6 [Homo sapiens] 404 e-113
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 403 e-112
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 402 e-112
gi|59958373 PRAME family member 4 [Homo sapiens] 400 e-111
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 361 e-100
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 361 e-100
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 361 e-100
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 971 bits (2511), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474
YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 844 bits (2180), Expect = 0.0
Identities = 416/474 (87%), Positives = 436/474 (91%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FL LPLGSLMKT HLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVED PR GEHQPLKVFIDLC KESTLDECLSYL WIHYRRGLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LFLA
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
FGY+ ELYVS Q +PDLD PFLCLYYPQMLYI+KISNIKEHLEHLLR LKNPLG FIF
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
AYL D+DMECLSQYPSLSQLKEL LIHILMWTT+LEPLG LLEKVAATL+ L LKDC+
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HTGGLSKLGLELYPAPLE LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474
+GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 842 bits (2175), Expect = 0.0
Identities = 415/474 (87%), Positives = 435/474 (91%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FL LPLGSLMKT HLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAM KRQTVED PR GEHQPLKVFIDLC KESTLDECLSYL WIHYRRGLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LFLA
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
FGY+ ELYVS Q +PDLD PFLCLYYPQMLYI+KISNIKEHLEHLLR LKNPLG FIF
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
AYL D+DMECLSQYPSLSQLKEL LIHILMWTT+LEPLG LLEKVAATL+ L LKDC+
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HTGGLSKLGLELYPAPLE LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474
+GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 827 bits (2137), Expect = 0.0
Identities = 418/474 (88%), Positives = 418/474 (88%), Gaps = 48/474 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FL LPLGSLMKT HLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
VLSCSPEAMSKRQTVEDCPRMGE QPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
RYLKNPLGAFIF
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
SDAYL DRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHT GLSKLGLELYPAPLESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474
YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCP CGSWPSEKVDFHLCS
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 827 bits (2135), Expect = 0.0
Identities = 418/474 (88%), Positives = 419/474 (88%), Gaps = 48/474 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FL LPLGSLMKT HLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
VLSCSPEAMSKRQTVEDCPRMGE QPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
RYLKNPLGAFIF
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTT+LEPLGVLLEKVAATLKTLVLKDCR
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHT GLSKLGLELYPAPLESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474
YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCP CGSWPSEKVDFHLCS
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 585 bits (1508), Expect = e-167
Identities = 298/473 (63%), Positives = 359/473 (75%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKT LE L V+ G+D L+AQKVRPRRWKLQVL+LRDVDENFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+ YLSQM NLR+LF++
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
G L Q + + S L L Y QMLY++++ + HL+ L+R L++PL
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
+ +L D++CL +YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHTG LS L LE YPAP ESLD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
+G V E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 579 bits (1492), Expect = e-165
Identities = 297/473 (62%), Positives = 357/473 (75%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKT LE L V+ G+D L+AQKVRPRR KLQVL+LRDVDENFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F YLSQM NLR+LF++
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
G L Q + + S L L Y QMLY++++ + HL+ L+R L++PL
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
+ +L D++CL +YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHTG LS L LE YPAP ESLD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
+G V E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 577 bits (1488), Expect = e-165
Identities = 295/473 (62%), Positives = 354/473 (74%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS QAP RLLELAGQSLLR+Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKT LE L V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE ++DE LS+ GW+ +RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C + + YLSQM NLR+LF++
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
G Q + + S FL L Y QMLY+++I + +L+ L+R LK+PL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
+ L + D++CL YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHTG LS L LE YPAP ESLD
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
+G V E+LTP++AELMR LREVR+P RIFFGPV CP CG P+E+++F+ C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 574 bits (1479), Expect = e-164
Identities = 294/473 (62%), Positives = 353/473 (74%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS QAP RLLELAGQSLLR+Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKT LE L V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE ++DE LS+ GW+ +RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C + + YLSQM NLR+LF++
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
G Q + + S FL L Y QMLY+++I + +L+ L+R LK+PL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
+ L + D++CL YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHTG LS L LE YPAP ESLD
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
+G V E+LTP++AELMR LREVR+P RIFFGPV CP CG P+E+++F+ C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 555 bits (1430), Expect = e-158
Identities = 288/473 (60%), Positives = 340/473 (71%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAFS R F+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKTLHLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSC PE SKRQT EDCPRMGEHQPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CCSK+ NY P R L+ IY +SIQELE+ K YL +M NLR+L +
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
+ +Q + S FL L + Q+L IK I+ HLE L+R L+NPL
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+LKTL+L+ C+
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I QL +LPALS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
VNWEI TP+RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 547 bits (1409), Expect = e-156
Identities = 283/473 (59%), Positives = 337/473 (71%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKTLHLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSC PE MSKRQT EDCPRMGEHQPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L +
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
+ ++ + S FL L + Q+L IK I+ HLE L+R L+NPL
Sbjct: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+L+TL+L+ C+
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I QL +LP LSHCSQLTTF F N SM ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 531 bits (1367), Expect = e-151
Identities = 278/473 (58%), Positives = 334/473 (70%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +F EAFS R F+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL SLMKTLHLE L+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSC PEAMSKRQT EDCPR GEHQPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CCSK+ NY P R L+ IY +SI ELE+ C + K YL +M L +L +
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
+ ++ + S FL L + Q+L IK I+ HLE L+R L+NPL
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
+ L + D++CLSQ+PSL LK L L ++L++ LEPLG LLEK+AA+L+TLVL+ C+
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I QL +LP LS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
VNWEI TP+RAELM TLRE RQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 508 bits (1309), Expect = e-144
Identities = 269/473 (56%), Positives = 315/473 (66%), Gaps = 48/473 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKTLHLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSC PE MSKRQT EDCPRMGEHQPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L +
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
R L+NPL
Sbjct: 241 ------------------------------------------------RCLQNPLENLEL 252
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+L+TL+L+ C+
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I QL +LP LSHCSQLTTF F N SM ALKDLL HT GLSKL LE YPAP ESL+
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 504 bits (1299), Expect = e-143
Identities = 272/462 (58%), Positives = 327/462 (70%), Gaps = 1/462 (0%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKT LE L V+ G+D L+AQKVRPRR KLQVL+LRDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+PYLSQM NLR+LF++
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
G R L S I + FL L+ Q LY+ +S ++ HL+ LL LK L
Sbjct: 241 DGC-RYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I D Q+ +LPALS C +L TF+F GN SM L++LL HT L L LELYPAP ES
Sbjct: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
G + W T IRAELM+ +R++R PKRI FG CP+CG+
Sbjct: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 460 bits (1183), Expect = e-129
Identities = 256/470 (54%), Positives = 318/470 (67%), Gaps = 19/470 (4%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAP RLLELA QSLLR++ L I TL+ELPRE+FP +FMEAF+ R E L MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMK+ +LE +AVL GLD L+AQKVRPRRWKLQVLDLR+VDENFW IWSGA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LS PEA+SKR+T +CPR G QPL V +DLC K LDECL++ W R+GL+H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC ++Q + + +L + D IQE+EV L+ +FAPYL QM NLR+L L
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 241 FGYERELYVSVQWPCIP---------DLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYL 291
++VS CIP S FL L Y Q LY+ +S ++ HL+ LLR L
Sbjct: 239 -----NIHVSA---CIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCL 290
Query: 292 KNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATL 351
+ PL + ++ L++ D++ LS PS+ QLKEL L I + EPL VLLE+ ATL
Sbjct: 291 QAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATL 350
Query: 352 KTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLEL 411
+TL L+DC I D QL +LPALS CSQL+TF+F GN SM AL++LLRHT GLSKL LEL
Sbjct: 351 QTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410
Query: 412 YPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
YPAPLES D +G + W + + AELM+TLR++RQPK I F VPCP CG
Sbjct: 411 YPAPLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCG 460
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 446 bits (1146), Expect = e-125
Identities = 248/463 (53%), Positives = 315/463 (68%), Gaps = 5/463 (1%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++AP RLLELA Q LLR+Q L I T++ELPRE+FP +FMEAFS RR E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMK+ HLE+L++VL G+D L+ Q+VRPR+ KLQVLDLR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
+ PEA+S++QT ++CP G QP VFIDLCLK TLDECL++L W R+GL+H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC ++Q + MP S +L + D IQE+EV L+ KFAPYL QM NLR+L L
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
Query: 241 FGYERELYVSV--QWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
F + + I S FL L Y Q L + +S ++ HL+ LLR L+ L
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
+ +D L++ D++ LS PS+ QLKEL L + + EPL LLE+V ATL+TL L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D QL +LP LS CSQL+TF+F GN SM AL++LLRHT GLSKL LELYPAPLES
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
D +G + W + AELM+TLR++RQPK I F VPCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 446 bits (1146), Expect = e-125
Identities = 248/463 (53%), Positives = 315/463 (68%), Gaps = 5/463 (1%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++AP RLLELA Q LLR+Q L I T++ELPRE+FP +FMEAFS RR E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMK+ HLE+L++VL G+D L+ Q+VRPR+ KLQVLDLR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
+ PEA+S++QT ++CP G QP VFIDLCLK TLDECL++L W R+GL+H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC ++Q + MP S +L + D IQE+EV L+ KFAPYL QM NLR+L L
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
Query: 241 FGYERELYVSV--QWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
F + + I S FL L Y Q L + +S ++ HL+ LLR L+ L
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
+ +D L++ D++ LS PS+ QLKEL L + + EPL LLE+V ATL+TL L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D QL +LP LS CSQL+TF+F GN SM AL++LLRHT GLSKL LELYPAPLES
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
D +G + W + AELM+TLR++RQPK I F VPCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 443 bits (1139), Expect = e-124
Identities = 247/463 (53%), Positives = 314/463 (67%), Gaps = 5/463 (1%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++AP RLLELA Q LLR+Q L I T++ELPRE+FP +FMEAFS RR E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMK+ HLE+L++VL G+D L+ Q+VRPR+ KLQVLDLR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
+ PEA+S++QT ++CP G QP VFIDLCLK TLDECL++L W R+GL+H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC ++Q + MP S +L + D IQE+EV L+ KFAPYL QM NLR+L L
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
Query: 241 FGYERELYVSV--QWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
F + + I S FL L Y Q L + +S ++ HL+ LLR L+ L
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
+ +D L++ D++ LS PS+ QLKEL L + + EPL LLE+V ATL+TL L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D QL +LP LS CSQL+TF+F GN SM AL++LLRHT GLSKL LELYPAPLES
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
D +G + W + AELM+T R++RQPK I F VPCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCG 460
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 424 bits (1091), Expect = e-119
Identities = 236/462 (51%), Positives = 296/462 (64%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR++ L I TL+ELP E+FP +FMEAFS R EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FL LPLGSLMK ET QAVL GLD L+ +VR RRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C P AM R+ V+DCPRM QPL VFIDLCLK TLDE + LF W+ R GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ M + RN+L+ + D IQE+EV +L +F PYL QM NLR+L L+
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
R + + + + FL L Q LY+ +S ++ HL+ +L LK L
Sbjct: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
++ L + D++ LS+YPS+ QLK L L + L PL VLLEKVAATL+ L L DC
Sbjct: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I D Q+ +LPALS C +LTTF+F GN S L++LL HT L+ L LELYPAP ES D
Sbjct: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
+G V + AELM +R +R+P+RI F CP CG+
Sbjct: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 424 bits (1091), Expect = e-119
Identities = 236/462 (51%), Positives = 296/462 (64%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR++ L I TL+ELP E+FP +FMEAFS R EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FL LPLGSLMK ET QAVL GLD L+ +VR RRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C P AM R+ V+DCPRM QPL VFIDLCLK TLDE + LF W+ R GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ M + RN+L+ + D IQE+EV +L +F PYL QM NLR+L L+
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
R + + + + FL L Q LY+ +S ++ HL+ +L LK L
Sbjct: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
Query: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
++ L + D++ LS+YPS+ QLK L L + L PL VLLEKVAATL+ L L DC
Sbjct: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
Query: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
I D Q+ +LPALS C +LTTF+F GN S L++LL HT L+ L LELYPAP ES D
Sbjct: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
Query: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
+G V + AELM +R +R+P+RI F CP CG+
Sbjct: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 408 bits (1049), Expect = e-114
Identities = 231/464 (49%), Positives = 295/464 (63%), Gaps = 3/464 (0%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL L+K LE QAVL GLD L+ Q VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ V+DCPRM QPL VF++L LK TLDE L+YL W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
+ YVS + + + FL L Q LY+ +S ++ HL+ LL LK L
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D Q+ +LPALS C +L TF+F GN M L++LL HT L L +ELYPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
G + W IRAELM +R++R PKRI F CP+CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 408 bits (1049), Expect = e-114
Identities = 231/464 (49%), Positives = 295/464 (63%), Gaps = 3/464 (0%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL L+K LE QAVL GLD L+ Q VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ V+DCPRM QPL VF++L LK TLDE L+YL W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
+ YVS + + + FL L Q LY+ +S ++ HL+ LL LK L
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D Q+ +LPALS C +L TF+F GN M L++LL HT L L +ELYPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
G + W IRAELM +R++R PKRI F CP+CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 405 bits (1040), Expect = e-113
Identities = 230/464 (49%), Positives = 295/464 (63%), Gaps = 3/464 (0%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL L+K LE QAVL GLD L+ Q V PRRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ V+DCPRM QPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
+ YVS + + + FL L Q L + +S ++ HL+ LL LK L
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D Q+ +LPALS C +L TF+F GN SM L++LL HT L L +ELYPAP ES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
D G + W IRAELM+ +R++R PKRI F CP+CG+
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 404 bits (1039), Expect = e-113
Identities = 230/464 (49%), Positives = 294/464 (63%), Gaps = 3/464 (0%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL L+K LE QAVL GLD L+ Q V PRRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A + V+DCPRM QPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
+ YVS + + + FL L Q L + +S ++ HL+ LL LK L
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D Q+ +LPALS C +L TF+F GN SM L++LL HT L L +ELYPAP ES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
D G + W IRAELM+ +R++R PKRI F CP+CG+
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 403 bits (1036), Expect = e-112
Identities = 230/464 (49%), Positives = 295/464 (63%), Gaps = 3/464 (0%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL L+K LE QAVL GLD L+ Q V PRRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ V+DCPRM QPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
+ YVS + + + FL L Q L + +S ++ HL+ LL LK L
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D Q+ +LPALS C +L TF+F GN SM L++LL HT L L +ELYPAP ES
Sbjct: 360 CGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
D G + W IRAELM+ +R++R PKRI F CP+CG+
Sbjct: 420 YDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 402 bits (1032), Expect = e-112
Identities = 230/463 (49%), Positives = 291/463 (62%), Gaps = 3/463 (0%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLEL G+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL L+K LE QAVL GLD L+ Q VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A + V+DCPRM E QPL VF++L LK TLDE L+ L W+ RR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ MP + R++L+ + D IQE+EV K L +F PYL + NL++L L+
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
Query: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
+ YVS + + + FL L Q LY+ +S ++ HL+ LL LK L
Sbjct: 278 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D Q+ +LPALS C +L TF+F GN M L++LL HT L L LELYPAP ES
Sbjct: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
G + W IRAELM+ +R +R PKRI F CP+ G
Sbjct: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHG 499
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 400 bits (1027), Expect = e-111
Identities = 229/464 (49%), Positives = 292/464 (62%), Gaps = 3/464 (0%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL L+K LE QAVL GLD L+ VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ VEDCPRM QPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
Query: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
+ YVS + + + FL L Q LY+ +S ++ HL+ LL LK L
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
Query: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
C I D Q+ +LPALS C +L TF+F GN M L++LL HT L L +ELYPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
G + W IRAELM +R++R PKRI F CP+CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 361 bits (926), Expect = e-100
Identities = 213/471 (45%), Positives = 291/471 (61%), Gaps = 15/471 (3%)
Query: 5 APSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLSL 64
+P RL+ELAGQSLL+++ L I L+ LPRE+FP +FM AF R + LK MVQAWPF L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLR-DVDENFWTIWSGARV 121
PLG LMK LHLET +AVL GLD L+AQ+VRPRRWKLQVLDLR + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MSKRQTVEDCPRMGEHQ--PLKVFIDLCLKESTLDECLSYLFGWIHY 173
S PEA M+K++ V+ E P++V +DL LKE DE SYL +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSN 233
++ ++ LCC K++ ++MP + +L+ + DSI++LEV L KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRELFLAFGYERELYVSVQWP--CIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYL 291
LR L L+ + Y+S + I S FL L Q LY+ + ++ L+ LLR++
Sbjct: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 KNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATL 351
NPL ++ L++ D+ LSQ PS+SQL L L +++ EPL LLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 KTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLEL 411
+ LV +C I D QL LLP+LSHCSQLTT +F+GN S++AL+ LL+H GLS L L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPLESL-DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
YP PLES D G ++ E L + A L L E+ +P ++ PCP+CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 361 bits (926), Expect = e-100
Identities = 213/471 (45%), Positives = 291/471 (61%), Gaps = 15/471 (3%)
Query: 5 APSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLSL 64
+P RL+ELAGQSLL+++ L I L+ LPRE+FP +FM AF R + LK MVQAWPF L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLR-DVDENFWTIWSGARV 121
PLG LMK LHLET +AVL GLD L+AQ+VRPRRWKLQVLDLR + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MSKRQTVEDCPRMGEHQ--PLKVFIDLCLKESTLDECLSYLFGWIHY 173
S PEA M+K++ V+ E P++V +DL LKE DE SYL +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSN 233
++ ++ LCC K++ ++MP + +L+ + DSI++LEV L KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRELFLAFGYERELYVSVQWP--CIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYL 291
LR L L+ + Y+S + I S FL L Q LY+ + ++ L+ LLR++
Sbjct: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 KNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATL 351
NPL ++ L++ D+ LSQ PS+SQL L L +++ EPL LLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 KTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLEL 411
+ LV +C I D QL LLP+LSHCSQLTT +F+GN S++AL+ LL+H GLS L L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPLESL-DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
YP PLES D G ++ E L + A L L E+ +P ++ PCP+CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 361 bits (926), Expect = e-100
Identities = 213/471 (45%), Positives = 291/471 (61%), Gaps = 15/471 (3%)
Query: 5 APSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLSL 64
+P RL+ELAGQSLL+++ L I L+ LPRE+FP +FM AF R + LK MVQAWPF L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLR-DVDENFWTIWSGARV 121
PLG LMK LHLET +AVL GLD L+AQ+VRPRRWKLQVLDLR + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MSKRQTVEDCPRMGEHQ--PLKVFIDLCLKESTLDECLSYLFGWIHY 173
S PEA M+K++ V+ E P++V +DL LKE DE SYL +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSN 233
++ ++ LCC K++ ++MP + +L+ + DSI++LEV L KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRELFLAFGYERELYVSVQWP--CIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYL 291
LR L L+ + Y+S + I S FL L Q LY+ + ++ L+ LLR++
Sbjct: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 KNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATL 351
NPL ++ L++ D+ LSQ PS+SQL L L +++ EPL LLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 KTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLEL 411
+ LV +C I D QL LLP+LSHCSQLTT +F+GN S++AL+ LL+H GLS L L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPLESL-DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
YP PLES D G ++ E L + A L L E+ +P ++ PCP+CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,168,794
Number of Sequences: 37866
Number of extensions: 801895
Number of successful extensions: 2400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2290
Number of HSP's gapped (non-prelim): 48
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.