BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo sapiens] (494 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo s... 1019 0.0 gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo s... 683 0.0 gi|150170670 piccolo isoform 2 [Homo sapiens] 65 1e-10 gi|150378539 piccolo isoform 1 [Homo sapiens] 65 1e-10 gi|11386183 WAS protein family, member 2 [Homo sapiens] 61 3e-09 gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 59 1e-08 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 58 2e-08 gi|153792074 proline rich 12 [Homo sapiens] 57 3e-08 gi|210032580 SET domain containing 1B [Homo sapiens] 56 9e-08 gi|157168329 formin 1 [Homo sapiens] 55 1e-07 gi|40807465 zinc finger protein 341 [Homo sapiens] 55 1e-07 gi|146134388 YLP motif containing 1 [Homo sapiens] 55 1e-07 gi|90903231 huntingtin [Homo sapiens] 54 3e-07 gi|52485606 formin-like 2 [Homo sapiens] 54 3e-07 gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 54 4e-07 gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 54 4e-07 gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 54 4e-07 gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 54 4e-07 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 54 4e-07 gi|33356148 formin-like 1 [Homo sapiens] 53 6e-07 gi|56549694 enabled homolog isoform a [Homo sapiens] 52 9e-07 gi|39930375 enabled homolog isoform b [Homo sapiens] 52 9e-07 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 52 1e-06 gi|145309324 FH2 domain containing 1 [Homo sapiens] 52 1e-06 gi|149944526 additional sex combs like 3 [Homo sapiens] 52 1e-06 gi|55741677 SET domain containing 1A [Homo sapiens] 50 4e-06 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 50 4e-06 gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming... 50 4e-06 gi|4557329 fas ligand [Homo sapiens] 50 5e-06 gi|33239445 eukaryotic translation initiation factor 3, subunit ... 50 5e-06 >gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo sapiens] Length = 494 Score = 1019 bits (2634), Expect = 0.0 Identities = 494/494 (100%), Positives = 494/494 (100%) Query: 1 MEVVEAAAAQLETLKFNGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVK 60 MEVVEAAAAQLETLKFNGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVK Sbjct: 1 MEVVEAAAAQLETLKFNGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVK 60 Query: 61 PAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDS 120 PAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDS Sbjct: 61 PAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDS 120 Query: 121 DSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLN 180 DSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLN Sbjct: 121 DSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLN 180 Query: 181 ELPSVEELTIILPEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKI 240 ELPSVEELTIILPEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKI Sbjct: 181 ELPSVEELTIILPEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKI 240 Query: 241 FEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKGSDAS 300 FEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKGSDAS Sbjct: 241 FEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKGSDAS 300 Query: 301 WKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPGEDFTEVHQNWNAHSS 360 WKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPGEDFTEVHQNWNAHSS Sbjct: 301 WKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPGEDFTEVHQNWNAHSS 360 Query: 361 ASEHAKGYRNREFTRGFSRARYPRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMP 420 ASEHAKGYRNREFTRGFSRARYPRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMP Sbjct: 361 ASEHAKGYRNREFTRGFSRARYPRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMP 420 Query: 421 QYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPP 480 QYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPP Sbjct: 421 QYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPP 480 Query: 481 PSSGDSNSHFGPYY 494 PSSGDSNSHFGPYY Sbjct: 481 PSSGDSNSHFGPYY 494 >gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo sapiens] Length = 389 Score = 683 bits (1763), Expect = 0.0 Identities = 345/345 (100%), Positives = 345/345 (100%) Query: 1 MEVVEAAAAQLETLKFNGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVK 60 MEVVEAAAAQLETLKFNGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVK Sbjct: 1 MEVVEAAAAQLETLKFNGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVK 60 Query: 61 PAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDS 120 PAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDS Sbjct: 61 PAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDS 120 Query: 121 DSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLN 180 DSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLN Sbjct: 121 DSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLN 180 Query: 181 ELPSVEELTIILPEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKI 240 ELPSVEELTIILPEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKI Sbjct: 181 ELPSVEELTIILPEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKI 240 Query: 241 FEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKGSDAS 300 FEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKGSDAS Sbjct: 241 FEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKGSDAS 300 Query: 301 WKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPG 345 WKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPG Sbjct: 301 WKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPG 345 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 65.5 bits (158), Expect = 1e-10 Identities = 91/411 (22%), Positives = 159/411 (38%), Gaps = 81/411 (19%) Query: 98 SPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPV----- 152 +PG++ P +AP + ++S D D D+ +SS S +S + S+SS+ +S+P V Sbjct: 2077 TPGSS-PTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQH 2135 Query: 153 --LSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIELKPLGMVSSIIEQ 210 + +D+ + + + + L+L E T + P D ++S + Sbjct: 2136 FSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTP-----SLTSSVSS 2190 Query: 211 LVIIESMTNLPPVNEETVIFKSDRQAAGKIFEIFGPVAHPFYVLRFNSS--DHIESKGIK 268 + +S + + ++ T ++ K FE ++ Y F S D+ E + Sbjct: 2191 VCTTDSSSPITTLDSITTVYTEPVDMITK-FEDSEEISSSTY---FPGSIIDYPEEISVS 2246 Query: 269 IKETM---------YFAPSMKDFTQYIFTEKLKQDKGSDASWKNDQEPPPEALDFSDDEK 319 + T + S+ D I + + +G A + L S+ + Sbjct: 2247 LDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTD------LLISEKDP 2300 Query: 320 EKEAKQRKKSQI--------QGRKKLKSEFNEPGEDFTEVHQNWNAHSSASEHAKGYRNR 371 K+AK+ + I + +K+L++E + + + + H +S A + + Sbjct: 2301 VKKAKKETGNGIILEVLEAYRDKKELEAERTK-----SSLSETVFDHPPSSVIALPMKEQ 2355 Query: 372 EFTRGFSRARYPRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDM 431 T F+ + E SQ SG PS + P P+ F D+ Sbjct: 2356 LSTTYFTSGET-------------FGQEKPASQLPSGSPSV-SSLPAKPRPFFRSSSLDI 2401 Query: 432 HNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPS 482 P PPPPPPPPP PPPPPPPPLPPP S Sbjct: 2402 SAQPPPPPPPPPPPPPP--------------------PPPPPPPPLPPPTS 2432 Score = 41.6 bits (96), Expect = 0.002 Identities = 66/322 (20%), Positives = 117/322 (36%), Gaps = 40/322 (12%) Query: 57 VEVKPAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDS 116 +E P+G P + T QPQPP C P EP + + E D Sbjct: 1295 MEGLPSGTPQSLPKEDDKTTKTIKEQPQPP--------CTAKPDQVEPGK--EKTEKEDD 1344 Query: 117 DSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDE 176 SD+ S S S + SS SSS +P ++ + D+ + +F ++ Sbjct: 1345 KSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS 1404 Query: 177 LLLNELPSVEELTIILPEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQA 236 ++L +E + + E S++ ++ E T V+ E + Q+ Sbjct: 1405 -SPSDLAKLESTVLSILE-------AQASTLADEK--SEKKTQPHEVSPEQPKDQEKTQS 1454 Query: 237 AGKIFEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKG 296 + EI S + I+ + K+T KD Q I + K ++K Sbjct: 1455 LSETLEI------------TISEEEIKESQEERKDTF-----KKDSQQDIPSSKDHKEKS 1497 Query: 297 SDASWKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRK---KLKSEFNEPGEDFTEVHQ 353 + P ++++ S + + QRK+ G + K E ++ + + + Sbjct: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIR 1557 Query: 354 NWNAHSSASEHAKGYRNREFTR 375 SA E A G + EF R Sbjct: 1558 KQIIEMSADEDASGSEDDEFIR 1579 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/128 (27%), Positives = 48/128 (37%), Gaps = 7/128 (5%) Query: 25 EGPA-APSPGSAPV----PGTQPPLQSFEGSPDAGQTVEVKPAGE--QPLQPVLNAVAAG 77 + PA AP P PV PG P Q+ G A QT KP + P +P Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487 Query: 78 TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137 P PQ A+ P+ T P +P A S + S + S S+ S + Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547 Query: 138 SSSSSSSS 145 S+ S+ Sbjct: 548 KPSAQQST 555 Score = 39.3 bits (90), Expect = 0.008 Identities = 30/99 (30%), Positives = 37/99 (37%), Gaps = 12/99 (12%) Query: 27 PAAPSPGSAPVP-----GTQPPLQSF-EGSPDAGQTVEVKPAGEQP------LQPVLNAV 74 P A PG+ P T+PP Q P A QT KP+ EQP P + Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400 Query: 75 AAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLET 113 A P P P + PG PA+AP +T Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439 Score = 39.3 bits (90), Expect = 0.008 Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 18/152 (11%) Query: 18 GTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQ--PLQPVLNAVA 75 GT + + P SP AP P P Q G A Q K + +Q P +P Sbjct: 416 GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475 Query: 76 AGTPAPQPQPPAESPACGDCVTSPGAAE-----------PARAPDSLETSDSDSDSDSET 124 P PQ PA+ P PG+A+ P + P + S S Sbjct: 476 PAKPPPQQPGPAKPPP-----QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530 Query: 125 DSDSSSSSSSSSSSSSSSSSSCISLPPVLSDG 156 S+ S+ S + S+ S PV G Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562 Score = 39.3 bits (90), Expect = 0.008 Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 14/130 (10%) Query: 26 GPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQP--LQPVLNAVAAGTPAPQ- 82 GP P P P P PP Q P Q KP +QP +P P+PQ Sbjct: 465 GPTKP-PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523 Query: 83 ---PQPPAESPACGDCVTSPGAAEPARAPDSLETSD---SDSDSDSETDSDSSSSSSSSS 136 +PP++ P P A +P+ A S + S S + S + S S+ Sbjct: 524 PGSTKPPSQQPGS----AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP 579 Query: 137 SSSSSSSSSC 146 S + C Sbjct: 580 PSQGLPKTIC 589 Score = 34.3 bits (77), Expect = 0.27 Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 9/83 (10%) Query: 404 QETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLN 463 Q G S +Q P P P P P + P P PPP G A P P Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKP----PPQQPGPAKPPPQQPGSAKP-----PSQQ 503 Query: 464 LPYSLPPPPPPPPLPPPPSSGDS 486 + PPP P P P P S Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGS 526 Score = 30.8 bits (68), Expect = 3.0 Identities = 43/177 (24%), Positives = 73/177 (41%), Gaps = 14/177 (7%) Query: 25 EGPAAPSPGSAPVPG--TQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQ 82 EG + +P S P T ++ P + +V+P E+ + + + + P+ Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355 Query: 83 -PQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSS 141 PQ +++ D ++S P+ P T + D + DS S SS SS S + Sbjct: 1356 SPQGLSDTGYSSDGISSSLGEIPSLIP----TDEKDILKGLKKDSFSQESSPSSPSDLAK 1411 Query: 142 SSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIEL 198 S+ +S +L L EK K KT+ + E P +E T L E +E+ Sbjct: 1412 LESTVLS---ILEAQASTLADEKSEK----KTQPHEVSPEQPKDQEKTQSLSETLEI 1461 Score = 29.6 bits (65), Expect = 6.6 Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 35/149 (23%) Query: 28 AAPSP--GSAPVPGTQPPL---QSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQ 82 AAP AP P PPL + GSP A +QP P ++++ + Sbjct: 688 AAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA--------KAKQP--PEADSLS------K 731 Query: 83 PQPPAESPACGDCVTSPGAAEPARAPDSLE-TSDSDSDSDSETDSDSSSSSSSSSSSSSS 141 P PP E + +P A + + P ++ T+D S S + T D SS S + + Sbjct: 732 PAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT 791 Query: 142 SSSSCISLPPVLSDGDDDLQIEKENKNFP 170 + PP+ +D K +++FP Sbjct: 792 T-------PPLKTDS------AKPSQSFP 807 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/59 (28%), Positives = 23/59 (38%), Gaps = 11/59 (18%) Query: 435 PLRPPPPPPPPPVNMGW-----------ATPNMAAHPLLNLPYSLPPPPPPPPLPPPPS 482 P++ P P PP G A P+ PL P ++ PP PP PP+ Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 65.5 bits (158), Expect = 1e-10 Identities = 91/411 (22%), Positives = 159/411 (38%), Gaps = 81/411 (19%) Query: 98 SPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPV----- 152 +PG++ P +AP + ++S D D D+ +SS S +S + S+SS+ +S+P V Sbjct: 2077 TPGSS-PTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQH 2135 Query: 153 --LSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIELKPLGMVSSIIEQ 210 + +D+ + + + + L+L E T + P D ++S + Sbjct: 2136 FSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTP-----SLTSSVSS 2190 Query: 211 LVIIESMTNLPPVNEETVIFKSDRQAAGKIFEIFGPVAHPFYVLRFNSS--DHIESKGIK 268 + +S + + ++ T ++ K FE ++ Y F S D+ E + Sbjct: 2191 VCTTDSSSPITTLDSITTVYTEPVDMITK-FEDSEEISSSTY---FPGSIIDYPEEISVS 2246 Query: 269 IKETM---------YFAPSMKDFTQYIFTEKLKQDKGSDASWKNDQEPPPEALDFSDDEK 319 + T + S+ D I + + +G A + L S+ + Sbjct: 2247 LDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTD------LLISEKDP 2300 Query: 320 EKEAKQRKKSQI--------QGRKKLKSEFNEPGEDFTEVHQNWNAHSSASEHAKGYRNR 371 K+AK+ + I + +K+L++E + + + + H +S A + + Sbjct: 2301 VKKAKKETGNGIILEVLEAYRDKKELEAERTK-----SSLSETVFDHPPSSVIALPMKEQ 2355 Query: 372 EFTRGFSRARYPRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDM 431 T F+ + E SQ SG PS + P P+ F D+ Sbjct: 2356 LSTTYFTSGET-------------FGQEKPASQLPSGSPSV-SSLPAKPRPFFRSSSLDI 2401 Query: 432 HNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPS 482 P PPPPPPPPP PPPPPPPPLPPP S Sbjct: 2402 SAQPPPPPPPPPPPPPP--------------------PPPPPPPPLPPPTS 2432 Score = 41.6 bits (96), Expect = 0.002 Identities = 66/322 (20%), Positives = 117/322 (36%), Gaps = 40/322 (12%) Query: 57 VEVKPAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDS 116 +E P+G P + T QPQPP C P EP + + E D Sbjct: 1295 MEGLPSGTPQSLPKEDDKTTKTIKEQPQPP--------CTAKPDQVEPGK--EKTEKEDD 1344 Query: 117 DSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDE 176 SD+ S S S + SS SSS +P ++ + D+ + +F ++ Sbjct: 1345 KSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS 1404 Query: 177 LLLNELPSVEELTIILPEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQA 236 ++L +E + + E S++ ++ E T V+ E + Q+ Sbjct: 1405 -SPSDLAKLESTVLSILE-------AQASTLADEK--SEKKTQPHEVSPEQPKDQEKTQS 1454 Query: 237 AGKIFEIFGPVAHPFYVLRFNSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKG 296 + EI S + I+ + K+T KD Q I + K ++K Sbjct: 1455 LSETLEI------------TISEEEIKESQEERKDTF-----KKDSQQDIPSSKDHKEKS 1497 Query: 297 SDASWKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRK---KLKSEFNEPGEDFTEVHQ 353 + P ++++ S + + QRK+ G + K E ++ + + + Sbjct: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIR 1557 Query: 354 NWNAHSSASEHAKGYRNREFTR 375 SA E A G + EF R Sbjct: 1558 KQIIEMSADEDASGSEDDEFIR 1579 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/128 (27%), Positives = 48/128 (37%), Gaps = 7/128 (5%) Query: 25 EGPA-APSPGSAPV----PGTQPPLQSFEGSPDAGQTVEVKPAGE--QPLQPVLNAVAAG 77 + PA AP P PV PG P Q+ G A QT KP + P +P Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487 Query: 78 TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137 P PQ A+ P+ T P +P A S + S + S S+ S + Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547 Query: 138 SSSSSSSS 145 S+ S+ Sbjct: 548 KPSAQQST 555 Score = 39.3 bits (90), Expect = 0.008 Identities = 30/99 (30%), Positives = 37/99 (37%), Gaps = 12/99 (12%) Query: 27 PAAPSPGSAPVP-----GTQPPLQSF-EGSPDAGQTVEVKPAGEQP------LQPVLNAV 74 P A PG+ P T+PP Q P A QT KP+ EQP P + Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400 Query: 75 AAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLET 113 A P P P + PG PA+AP +T Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439 Score = 39.3 bits (90), Expect = 0.008 Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 18/152 (11%) Query: 18 GTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQ--PLQPVLNAVA 75 GT + + P SP AP P P Q G A Q K + +Q P +P Sbjct: 416 GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475 Query: 76 AGTPAPQPQPPAESPACGDCVTSPGAAE-----------PARAPDSLETSDSDSDSDSET 124 P PQ PA+ P PG+A+ P + P + S S Sbjct: 476 PAKPPPQQPGPAKPPP-----QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530 Query: 125 DSDSSSSSSSSSSSSSSSSSSCISLPPVLSDG 156 S+ S+ S + S+ S PV G Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562 Score = 39.3 bits (90), Expect = 0.008 Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 14/130 (10%) Query: 26 GPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQP--LQPVLNAVAAGTPAPQ- 82 GP P P P P PP Q P Q KP +QP +P P+PQ Sbjct: 465 GPTKP-PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523 Query: 83 ---PQPPAESPACGDCVTSPGAAEPARAPDSLETSD---SDSDSDSETDSDSSSSSSSSS 136 +PP++ P P A +P+ A S + S S + S + S S+ Sbjct: 524 PGSTKPPSQQPGS----AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP 579 Query: 137 SSSSSSSSSC 146 S + C Sbjct: 580 PSQGLPKTIC 589 Score = 34.3 bits (77), Expect = 0.27 Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 9/83 (10%) Query: 404 QETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLN 463 Q G S +Q P P P P P + P P PPP G A P P Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKP----PPQQPGPAKPPPQQPGSAKP-----PSQQ 503 Query: 464 LPYSLPPPPPPPPLPPPPSSGDS 486 + PPP P P P P S Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGS 526 Score = 30.8 bits (68), Expect = 3.0 Identities = 43/177 (24%), Positives = 73/177 (41%), Gaps = 14/177 (7%) Query: 25 EGPAAPSPGSAPVPG--TQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQ 82 EG + +P S P T ++ P + +V+P E+ + + + + P+ Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355 Query: 83 -PQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSS 141 PQ +++ D ++S P+ P T + D + DS S SS SS S + Sbjct: 1356 SPQGLSDTGYSSDGISSSLGEIPSLIP----TDEKDILKGLKKDSFSQESSPSSPSDLAK 1411 Query: 142 SSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIEL 198 S+ +S +L L EK K KT+ + E P +E T L E +E+ Sbjct: 1412 LESTVLS---ILEAQASTLADEKSEK----KTQPHEVSPEQPKDQEKTQSLSETLEI 1461 Score = 29.6 bits (65), Expect = 6.6 Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 35/149 (23%) Query: 28 AAPSP--GSAPVPGTQPPL---QSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQ 82 AAP AP P PPL + GSP A +QP P ++++ + Sbjct: 688 AAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA--------KAKQP--PEADSLS------K 731 Query: 83 PQPPAESPACGDCVTSPGAAEPARAPDSLE-TSDSDSDSDSETDSDSSSSSSSSSSSSSS 141 P PP E + +P A + + P ++ T+D S S + T D SS S + + Sbjct: 732 PAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT 791 Query: 142 SSSSCISLPPVLSDGDDDLQIEKENKNFP 170 + PP+ +D K +++FP Sbjct: 792 T-------PPLKTDS------AKPSQSFP 807 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/59 (28%), Positives = 23/59 (38%), Gaps = 11/59 (18%) Query: 435 PLRPPPPPPPPPVNMGW-----------ATPNMAAHPLLNLPYSLPPPPPPPPLPPPPS 482 P++ P P PP G A P+ PL P ++ PP PP PP+ Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 60.8 bits (146), Expect = 3e-09 Identities = 60/216 (27%), Positives = 86/216 (39%), Gaps = 55/216 (25%) Query: 318 EKEKEAKQRKKSQIQGR---KKLKSEFNE-----PGEDFTE--------------VHQNW 355 EK K K++K + +G +K+K+ E G++F E V+QN Sbjct: 174 EKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNG 233 Query: 356 NAHSSASEHAKGYRNREFTRGFSRARYPRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQN 415 + + A Y + S S PPP + S + +Q SG +++ Sbjct: 234 SIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEF-SYPVDNQRGSGLAGPKRS 292 Query: 416 NPIMPQYPFPLPV----------FDMHNFPLRPPP-----PPPPPPVNMGW-------AT 453 + + P +P P P F P PPP PPPPPPV G + Sbjct: 293 SVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSP 352 Query: 454 PNMAAHPLLNLPYSLPPPPPPPP------LPPPPSS 483 P+ HP ++ PPPPPPPP LPPPP S Sbjct: 353 PSFPPHP----DFAAPPPPPPPPAADYPTLPPPPLS 384 Score = 56.2 bits (134), Expect = 7e-08 Identities = 30/77 (38%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 416 NPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPP 475 +P P P P P F H PPPPPPPP + P + P P PPPPPP Sbjct: 343 SPGTPPPPSP-PSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG 401 Query: 476 PLPPPPSSGDSNSHFGP 492 P PPP + D P Sbjct: 402 PPPPPFTGADGQPAIPP 418 Score = 38.1 bits (87), Expect = 0.018 Identities = 34/113 (30%), Positives = 44/113 (38%), Gaps = 8/113 (7%) Query: 27 PAAPSPGSAPVPGTQPPLQ--SFEGSPD--AGQTVEVKPAGEQPL--QPVLNAVAAGTPA 80 P P P PGT PP SF PD A PA + P P L+ G P Sbjct: 333 PPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPP 392 Query: 81 PQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSS 133 P P PP P + G +PA P +T+ S + +D+ S S+ Sbjct: 393 PPPPPPPPGPPPPPFTGADG--QPAIPPPLSDTTKPKSSLPAVSDARSDLLSA 443 Score = 30.4 bits (67), Expect = 3.9 Identities = 40/182 (21%), Positives = 60/182 (32%), Gaps = 22/182 (12%) Query: 314 FSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPGEDFTEVHQNWNAHSSASEHAKGYRNREF 373 F D KEK + K + RK K + + P N N + + + + Sbjct: 156 FFDLWKEKMLQDTKDIMKEKRKHRKEKKDNPNRG------NVNPRKIKTRKEE-WEKMKM 208 Query: 374 TRGFSRARYPRSCHGRPPPQHFYNSEH--MVSQETSGFPSQRQNNPIMPQYPFPLPVFDM 431 + F ++ G PP + N + + + S +P Q++ P P F Sbjct: 209 GQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASS----PSPSFSE 264 Query: 432 HNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYS-LPPPPPPPPLPPPPSSGDSNSHF 490 N P PPP + N L S + P PPP PP S F Sbjct: 265 DNLP--------PPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGF 316 Query: 491 GP 492 P Sbjct: 317 AP 318 Score = 30.4 bits (67), Expect = 3.9 Identities = 14/37 (37%), Positives = 16/37 (43%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPP 446 P + P +P P P P PPPP PPPP Sbjct: 369 PPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPP 405 >gi|126090663 zinc finger homeodomain 4 [Homo sapiens] Length = 3571 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/56 (51%), Positives = 33/56 (58%), Gaps = 9/56 (16%) Query: 435 PLRPPPPPPPPPV--------NMGWAT-PNMAAHPLLNLPYSLPPPPPPPPLPPPP 481 P PPPPPPPPP+ +MG PN + PL P + PPPPPPPP PPPP Sbjct: 1955 PETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPP 2010 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 19/67 (28%) Query: 417 PIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPP 476 P P P+ + + + PL+ PPP PPPP PPPPPPPP Sbjct: 1971 PPQPSSMGPVKIPNTVSTPLQAPPPTPPPPP-------------------PPPPPPPPPP 2011 Query: 477 LPPPPSS 483 PPPPS+ Sbjct: 2012 PPPPPSA 2018 Score = 42.7 bits (99), Expect = 8e-04 Identities = 20/46 (43%), Positives = 20/46 (43%), Gaps = 20/46 (43%) Query: 435 PLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPP 480 P PPPPPPPPP PPPPPPPP PP Sbjct: 1995 PTPPPPPPPPPP--------------------PPPPPPPPPPSAPP 2020 Score = 41.2 bits (95), Expect = 0.002 Identities = 22/61 (36%), Positives = 28/61 (45%) Query: 423 PFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPS 482 P LP F ++ L PP ++P ++ P PPPPPPP PPPPS Sbjct: 3070 PSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPS 3129 Query: 483 S 483 S Sbjct: 3130 S 3130 Score = 37.0 bits (84), Expect = 0.041 Identities = 14/22 (63%), Positives = 15/22 (68%) Query: 465 PYSLPPPPPPPPLPPPPSSGDS 486 P + PPPPPPPPLPP P S Sbjct: 1955 PETPPPPPPPPPLPPAPPQPSS 1976 Score = 32.7 bits (73), Expect = 0.78 Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 7/87 (8%) Query: 27 PAAPS-PGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQP 85 P +PS P + P P PPL P + V++ PLQ P P P P Sbjct: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008 Query: 86 PAESPACGDCVTSPGAAEPARAPDSLE 112 P P P A + P SL+ Sbjct: 2009 PPPPP------PPPSAPPQVQLPVSLD 2029 Score = 32.7 bits (73), Expect = 0.78 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 434 FPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPP----PPPPPLPPPPSSGDSNS 488 FP PP +G+ T + + P L+L + P PPPPP PPPP S S Sbjct: 3076 FPQNSNTLTPPGAGMLGFPT-SATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLS 3133 Score = 32.3 bits (72), Expect = 1.0 Identities = 14/28 (50%), Positives = 15/28 (53%) Query: 465 PYSLPPPPPPPPLPPPPSSGDSNSHFGP 492 P S PPPPPP PP P + S GP Sbjct: 1952 PSSPETPPPPPPPPPLPPAPPQPSSMGP 1979 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 57.8 bits (138), Expect = 2e-08 Identities = 47/132 (35%), Positives = 57/132 (43%), Gaps = 8/132 (6%) Query: 31 SPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQP--VLNAVAAGTPAPQPQPPAE 88 S S+ + S S +G + P+QP L V + TPAP+ Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREG 2593 Query: 89 SPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCIS 148 P P A+ R S +S S S S S + S SSSSSSSSSSSSSSSSSS S Sbjct: 2594 RPP------EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647 Query: 149 LPPVLSDGDDDL 160 P G L Sbjct: 2648 SPSPAKPGPQAL 2659 Score = 50.1 bits (118), Expect = 5e-06 Identities = 54/150 (36%), Positives = 61/150 (40%), Gaps = 32/150 (21%) Query: 29 APSP----GSAPVPGTQPPLQSFEGSPDAG-----------QTVEVKPAGEQPLQPVLNA 73 APSP G AP PP Q SP QT V AG Q L A Sbjct: 2424 APSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV--AGSQSLSS--GA 2479 Query: 74 VAAGTPAPQ--------PQPPAESPACGDCVTSPGAAEPA-----RAPDSLETSDSDSDS 120 VA T + P P G+ S GA +P+ + +S S S S Sbjct: 2480 VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSS 2539 Query: 121 DSETDSDSSSSSSSSSSSSSSSSSSCISLP 150 S + S SSSSSSSSSS SSSS S SLP Sbjct: 2540 SSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569 Score = 39.3 bits (90), Expect = 0.008 Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 18/167 (10%) Query: 28 AAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQPPA 87 + P+PG +PP + P A ++PA E+ ++ ++ + + + Sbjct: 2495 SVPAPGVPHSDVGEPPASTGAQQPSA--LAALQPAKERRSSSSSSSSSSSSSSSSSSSSS 2552 Query: 88 ESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSET----------------DSDSSSS 131 S + S G++ P + +L+ S + + E S SSSS Sbjct: 2553 SSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612 Query: 132 SSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELL 178 SSSSSSSSSSSSSS S S + P K + L Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL 2659 Score = 37.4 bits (85), Expect = 0.032 Identities = 41/140 (29%), Positives = 53/140 (37%), Gaps = 24/140 (17%) Query: 24 GEGPAAPS-PG-------SAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVA 75 GEG A S PG S+P T+ P +E D + + K A P ++ Sbjct: 304 GEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE---DKDKDKKEKSATRPSPSPERSSTG 360 Query: 76 AGTPAP----------QPQPPAESPACGDCVTSPGAAEPAR---APDSLETSDSDSDSDS 122 PAP PQP A +P + V P A P R P S E S S+S Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420 Query: 123 ETDSDSSSSSSSSSSSSSSS 142 S + S +SSS S Sbjct: 421 SPPSPQPTKVSRHASSSPES 440 Score = 36.2 bits (82), Expect = 0.070 Identities = 42/172 (24%), Positives = 63/172 (36%), Gaps = 25/172 (14%) Query: 6 AAAAQLETLKFNGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFE--GSPDAGQTVEVKPAG 63 +AAA+ T G PA+ G P ++P S + SP+ P Sbjct: 281 SAAAKTHTTALAGRS----PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE 336 Query: 64 EQPLQPVLNAVAAGTPAPQ-----PQPPAESPACGD--------CVTSPGAAEPARAPDS 110 ++ + +P+P+ P+PPA +P + T+P + EP P Sbjct: 337 DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396 Query: 111 LETSDSDSDSDSETDSDSSSSSSSSSSS------SSSSSSSCISLPPVLSDG 156 + S S SSSS SS S S +SSS S P + G Sbjct: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPG 448 Score = 34.7 bits (78), Expect = 0.20 Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 13/124 (10%) Query: 24 GEGPAAPSP------GSAPVPGTQPPLQSFEGSP--DAGQTVEVKPAGEQPLQPVLNAVA 75 G P AP+P G +P P PL +P +A T + P P ++ Sbjct: 360 GPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSE 419 Query: 76 AGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSS 135 + P+PQP + + +SP + +PA AP S S S + + + S S Sbjct: 420 SSPPSPQPTKVSRHAS-----SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474 Query: 136 SSSS 139 + S Sbjct: 475 HTPS 478 Score = 34.3 bits (77), Expect = 0.27 Identities = 50/223 (22%), Positives = 80/223 (35%), Gaps = 32/223 (14%) Query: 289 EKLKQDKGSDASWKNDQEPPPEALDFSDDEKEKEAKQRK--------KSQIQGRKKLKSE 340 +K K+D+G + + + ++ E E+K+RK K + + +K+ +S Sbjct: 190 KKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSR 249 Query: 341 FNEPGEDFTEVHQNWNAHSSASEHAKGYRNREFTRGFSRARYPRSCHGRPP-PQHFYNSE 399 P H++ +A S++S +R +R + + + GR P P E Sbjct: 250 STTPAPKSRRAHRSTSADSASSSDT----SRSRSRSAAAKTHTTALAGRSPSPASGRRGE 305 Query: 400 HMVSQETSGFPS-QRQNNPI----MPQYPFPLPVFDM-HNFPLRPPPPP--------PPP 445 G S QR ++P P P+ D RP P P PP Sbjct: 306 GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA 365 Query: 446 PVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPP-----PPSS 483 P + + PL P S P PP P PP S Sbjct: 366 PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408 Score = 33.1 bits (74), Expect = 0.59 Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 9/117 (7%) Query: 29 APSP---GSAPVPGTQPPL--QSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQP 83 +PSP + P P PL + GSP Q + P ++P+ P A +P P Sbjct: 351 SPSPERSSTGPEPPAPTPLLAERHGGSP---QPLATTPLSQEPVNPPSEASPTRDRSP-P 406 Query: 84 QPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSS 140 + P + P +SP + +P + +S S SSS +S + S Sbjct: 407 KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRS 463 Score = 32.0 bits (71), Expect = 1.3 Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 15/125 (12%) Query: 33 GSAPVPGTQ---PPLQSFEGS----------PDAGQTVEVKPAGEQPLQPVLNAVAAGTP 79 GS+P P + PP +S GS P ++ P ++ P + + + Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP--SRQSHSSS 838 Query: 80 APQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSS 139 +P P+ + +P +TSP A E + P +S D + ++ + S S S SS Sbjct: 839 SPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898 Query: 140 SSSSS 144 SS+ Sbjct: 899 VKSST 903 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/84 (40%), Positives = 42/84 (50%), Gaps = 9/84 (10%) Query: 408 GFPSQRQNN----PIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLN 463 G PS N P++ + P P P P +PPPPPPPP + P +A P Sbjct: 1438 GLPSANSNGTPEPPLLEEKPPPTPPPAPTPQP-QPPPPPPPPQPALPSPPPLVAPTPSSP 1496 Query: 464 LPYSLPPPPPP----PPLPPPPSS 483 P LPPPPPP PP PPPP++ Sbjct: 1497 PPPPLPPPPPPAMPSPPPPPPPAA 1520 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/68 (39%), Positives = 30/68 (44%), Gaps = 20/68 (29%) Query: 417 PIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPP- 475 P P P P P+ + P PPPPP PPP P M + PPPPPPP Sbjct: 1477 PPQPALPSPPPL--VAPTPSSPPPPPLPPP-----PPPAMPS----------PPPPPPPA 1519 Query: 476 --PLPPPP 481 PL PP Sbjct: 1520 AAPLAAPP 1527 Score = 38.9 bits (89), Expect = 0.011 Identities = 27/65 (41%), Positives = 29/65 (44%), Gaps = 13/65 (20%) Query: 436 LRPPPPPPPPPVNMGWATPNMAAHPLL------NLPYSLPPPPP---PPPLPPPPSSGDS 486 L+ PPPPPP TP H LL +LP LPPPPP P L PS S Sbjct: 760 LQKSPPPPPPTAQSTQPTP----HGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPS 815 Query: 487 NSHFG 491 S G Sbjct: 816 ASKVG 820 Score = 38.1 bits (87), Expect = 0.018 Identities = 25/65 (38%), Positives = 32/65 (49%), Gaps = 8/65 (12%) Query: 433 NFPLRPPPPPPP--PPVNMGWATPNMAAHPL---LNLPYS---LPPPPPPPPLPPPPSSG 484 + PL PPPPP P V +P+ +A + L P + P PPPPPP PPPP Sbjct: 789 DLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPL 848 Query: 485 DSNSH 489 +H Sbjct: 849 QLEAH 853 Score = 36.6 bits (83), Expect = 0.054 Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 16/65 (24%) Query: 436 LRPPPPPPPP------PVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPSSGDSNSH 489 L P PP P P+ + + P+ AA PPPPPPPP PP P+S Sbjct: 1010 LDPNKPPELPSTVNAEPLGLIQSGPHQAA----------PPPPPPPPPPPAPASEPKGGL 1059 Query: 490 FGPYY 494 P + Sbjct: 1060 TSPIF 1064 Score = 36.6 bits (83), Expect = 0.054 Identities = 42/189 (22%), Positives = 70/189 (37%), Gaps = 28/189 (14%) Query: 15 KFNGTDFGVGEGPAAPSPGSAPVPGT---------QPPL--QSFEGSPDAGQTVEVKPAG 63 K T G PAA PG P+PG +PPL + +P T + +P Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPP 1473 Query: 64 E----QPLQPVLNAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSD 119 QP P + A TP+ P PP P + P PA AP L + Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP--LAAPPEEPA 1531 Query: 120 SDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLL 179 + S D + + + +++ C G+ D + + + +DE ++ Sbjct: 1532 APSPEDPELPDTRPLHLAKKQETAAVC---------GETDEEAGESGGEGIFRERDEFVI 1582 Query: 180 --NELPSVE 186 ++PS++ Sbjct: 1583 RAEDIPSLK 1591 Score = 36.2 bits (82), Expect = 0.070 Identities = 21/52 (40%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 435 PLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPP-----PLPPPP 481 PL P P PP G + N P L PPP PPP P PPPP Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP 1474 Score = 34.3 bits (77), Expect = 0.27 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 24/124 (19%) Query: 390 PPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQY----PFPLP----------VFDMHNFP 435 PPP+H ++++ ++ + Q++P + + P P P V + P Sbjct: 236 PPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRP 295 Query: 436 LRPPPPPPPPP-------VNMGWATPNMAAHPLLNLPYS-LPPPPPPPPLPPPPSSGDSN 487 PPPPPPP ++ G + P+M NL S L P P P +G S Sbjct: 296 ASAQPPPPPPPAHALQHYLSCGGSYPSMGHR--ANLACSPLGGGEPSPGAGEPSKAGPSG 353 Query: 488 SHFG 491 + G Sbjct: 354 ATAG 357 Score = 33.9 bits (76), Expect = 0.35 Identities = 23/82 (28%), Positives = 28/82 (34%), Gaps = 34/82 (41%) Query: 435 PLRPPPPPPPPP-------------VNMGWATPNMAAHPLLNLPYSLPPPPPP------- 474 P RP PP PPPP + A ++ L N + P PPPP Sbjct: 226 PYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQ 285 Query: 475 --------------PPLPPPPS 482 PP PPPP+ Sbjct: 286 DTVIKHYQRPASAQPPPPPPPA 307 Score = 33.1 bits (74), Expect = 0.59 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 10/62 (16%) Query: 435 PLRPPPPPPPPPVNM-----GWATPNMAAHPLLNLPYSLPPPPPPPPL-----PPPPSSG 484 P PPPPPPP P+ + A P L SL PP L P PP+ G Sbjct: 836 PPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPG 895 Query: 485 DS 486 D+ Sbjct: 896 DT 897 Score = 31.6 bits (70), Expect = 1.7 Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 23/70 (32%) Query: 438 PPPPPPPPPVNMGW-----------ATPNMAAHP------------LLNLPYSLPPPPPP 474 PPPPPPPPP+ + A P+ P LL LPP P Sbjct: 837 PPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGD 896 Query: 475 PPLPPPPSSG 484 + PP S G Sbjct: 897 TGVGPPNSEG 906 Score = 30.8 bits (68), Expect = 3.0 Identities = 40/166 (24%), Positives = 55/166 (33%), Gaps = 29/166 (17%) Query: 22 GVGEGPAAPS--------PGSAPVPGTQPPLQSFEGS--PDAGQTVEVKPAGEQPLQPVL 71 G G P P+ PG A G + P + + P+ TV +P G P Sbjct: 977 GAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQ 1036 Query: 72 NAVAAGTPAPQPQPPAESPACG-----DCVTSPGAA-------------EPARAPDSLET 113 A P P P PA P G C T P P + P L Sbjct: 1037 AAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYA 1096 Query: 114 SDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDD 159 + + ++D E +D + + SSC S P + GD D Sbjct: 1097 QEYEFEAD-EDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDID 1141 Score = 29.6 bits (65), Expect = 6.6 Identities = 16/44 (36%), Positives = 18/44 (40%), Gaps = 2/44 (4%) Query: 405 ETSGFPSQRQNNPIMPQY--PFPLPVFDMHNFPLRPPPPPPPPP 446 ET G P +P PL + PPPPPPPPP Sbjct: 1004 ETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPP 1047 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 55.8 bits (133), Expect = 9e-08 Identities = 33/75 (44%), Positives = 36/75 (48%), Gaps = 12/75 (16%) Query: 408 GFPSQRQNNPIMPQYP-FPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPY 466 GFP P P P FP+P P PPPPPPPPP + P P L P Sbjct: 686 GFPPLPPPPPPPPPQPGFPMP-------PPLPPPPPPPPPAHPAVTVPP----PPLPAPP 734 Query: 467 SLPPPPPPPPLPPPP 481 +PPPP PPLPP P Sbjct: 735 GVPPPPILPPLPPFP 749 Score = 52.0 bits (123), Expect = 1e-06 Identities = 28/77 (36%), Positives = 34/77 (44%), Gaps = 20/77 (25%) Query: 406 TSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLP 465 T G + + + P P P P FP PPPPPPPPP Sbjct: 663 TPGAAAVAAPSVLAPTLPLPPPP----GFPPLPPPPPPPPP----------------QPG 702 Query: 466 YSLPPPPPPPPLPPPPS 482 + +PPP PPPP PPPP+ Sbjct: 703 FPMPPPLPPPPPPPPPA 719 Score = 46.6 bits (109), Expect = 5e-05 Identities = 26/56 (46%), Positives = 28/56 (50%), Gaps = 15/56 (26%) Query: 435 PLRPPP--PPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPP-------LPPPP 481 PL PPP PP PPP P P +P LPPPPPPPP +PPPP Sbjct: 680 PLPPPPGFPPLPPP------PPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPP 729 Score = 38.5 bits (88), Expect = 0.014 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 7/60 (11%) Query: 430 DMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPP-----PPPPLPPPPSSG 484 +M + P+ P P V G A +AA +L LPPPP PPPP PPPP G Sbjct: 645 EMPSAPITSADCPKPMVVTPGAAA--VAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPG 702 Score = 36.6 bits (83), Expect = 0.054 Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 23/71 (32%) Query: 410 PSQRQNNPIMPQYPFPLPV-FDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSL 468 P Q Q P+ P P V D N + PPPP PP Sbjct: 1510 PGQPQT-PVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQP--------------------- 1547 Query: 469 PPPPPPPPLPP 479 PPPPPPPP+ P Sbjct: 1548 PPPPPPPPVEP 1558 Score = 34.3 bits (77), Expect = 0.27 Identities = 24/81 (29%), Positives = 30/81 (37%), Gaps = 36/81 (44%) Query: 418 IMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPP--- 474 + P+ P LP+ PL+PP PPP PP PP PPP Sbjct: 1266 VEPEPPMMLPL------PLQPPLPPPRPP---------------------RPPSPPPEPE 1298 Query: 475 ------PPLPPPPSSGDSNSH 489 P +PP P + D H Sbjct: 1299 TTDASHPSVPPEPLAEDHPPH 1319 Score = 33.9 bits (76), Expect = 0.35 Identities = 51/215 (23%), Positives = 81/215 (37%), Gaps = 7/215 (3%) Query: 278 SMKDFTQYIFTEKLKQDKGSDASWKNDQEPPPEAL-DFSDDEKEKEAKQRKKSQIQGRKK 336 S ++ T I T K + S++S ++ E E+ S+DE+E A++ ++ + + Sbjct: 1094 SDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMV 1153 Query: 337 LKSEFNEPG-EDFTEVHQNWN-AHSSASEHAKGYRNREFTRGFSRARYPRSCHGRPPPQH 394 + G EDF + + A + + + G + A R PP Sbjct: 1154 AEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLP 1213 Query: 395 FYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATP 454 E S+E P Q ++ P P P ++ P P P + + P Sbjct: 1214 VGVEEPADSREPPEEPGLSQEGAMLLS-PEP-PAKEVEARPPLSPERAPEHDLEVEPEPP 1271 Query: 455 NMAAHPLLNLPYSLPPPPPPPPLPPPPSSGDSNSH 489 M PL P PP PP PP PPP SH Sbjct: 1272 MMLPLPLQ--PPLPPPRPPRPPSPPPEPETTDASH 1304 Score = 33.9 bits (76), Expect = 0.35 Identities = 18/46 (39%), Positives = 18/46 (39%), Gaps = 4/46 (8%) Query: 440 PPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPP----PPPPLPPPP 481 P P PV P N PPPP PPPP PPPP Sbjct: 1510 PGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPP 1555 Score = 32.7 bits (73), Expect = 0.78 Identities = 53/239 (22%), Positives = 84/239 (35%), Gaps = 36/239 (15%) Query: 36 PVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQPPAESPACGDC 95 P P +P + G+ D+G+ P L GTP P P S G Sbjct: 408 PPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGR 467 Query: 96 VTSPGAAEPARAPDSLETSDSDSDSDSETDS----------------------DSSSSSS 133 T + EP +P + S + + DS DS + Sbjct: 468 PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQ 527 Query: 134 SSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKT-KDELLLNELPSV---EELT 189 S SSSSS L P ++ + + P T +++ LP EEL Sbjct: 528 MEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELD 587 Query: 190 IIL-----PEDIELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKIFEI 243 + L PE P G++S E V ++ + + P +E+ +Q++G+ EI Sbjct: 588 LGLGPRPPPEPGPPDPAGLLSQTAE--VALDLVGDRTPTSEK---MDEGQQSSGEDMEI 641 Score = 31.6 bits (70), Expect = 1.7 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 12/98 (12%) Query: 103 EPARAPDSLETSDSDSDSD---SETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDD 159 E ++ E + DSD + S S + ++SSS SS SS SS S P D ++ Sbjct: 1079 EDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEV 1138 Query: 160 LQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIE 197 + E+E +E E+ + E + PED E Sbjct: 1139 VAREEE---------EEEEEEEMVAEESMASAGPEDFE 1167 Score = 31.2 bits (69), Expect = 2.3 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 6/94 (6%) Query: 110 SLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKEN--- 166 S+ TS +++ S SE+ S SSS SS SSS + + +++ + +E+ Sbjct: 1101 SIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMAS 1160 Query: 167 ---KNFPLKTKDELLLNELPSVEELTIILPEDIE 197 ++F ++ L P+V+ L + DIE Sbjct: 1161 AGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIE 1194 Score = 30.8 bits (68), Expect = 3.0 Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 5/63 (7%) Query: 425 PLPVFDMHNFP-LRPPPPPPPPPVNMGWA----TPNMAAHPLLNLPYSLPPPPPPPPLPP 479 PL F ++ P R P PP P + G TP + L L P PPP P PP Sbjct: 542 PLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPP 601 Query: 480 PPS 482 P+ Sbjct: 602 DPA 604 Score = 30.0 bits (66), Expect = 5.0 Identities = 25/78 (32%), Positives = 28/78 (35%), Gaps = 9/78 (11%) Query: 420 PQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPP--PL 477 P P P F P + P PPP AT A + PPP PP PL Sbjct: 384 PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPL 443 Query: 478 -------PPPPSSGDSNS 488 PP P D+NS Sbjct: 444 AKEKPGTPPGPPPPDTNS 461 Score = 29.3 bits (64), Expect = 8.6 Identities = 18/60 (30%), Positives = 21/60 (35%), Gaps = 1/60 (1%) Query: 27 PAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQPP 86 P P PG P+P PP G P + P P P + PAP PP Sbjct: 680 PLPPPPGFPPLPPPPPPPPPQPGFP-MPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPP 738 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/53 (50%), Positives = 31/53 (58%), Gaps = 4/53 (7%) Query: 436 LRPPP----PPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPSSG 484 L PPP PPPP P +G +P P+ P PPPPPPPPLPPP S+G Sbjct: 645 LPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAG 697 Score = 52.8 bits (125), Expect = 7e-07 Identities = 46/167 (27%), Positives = 67/167 (40%), Gaps = 27/167 (16%) Query: 320 EKEAKQRKKSQIQGRKKLKSEFNE--PGEDFTEVHQNWNAHSSASEHAKGYRNREFTRGF 377 E E+K + +Q+ +K S ++ P D ++H +A + +G + + Sbjct: 594 ESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIH-------AALQPMEGMASNQ----- 641 Query: 378 SRARYPRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLR 437 + P PPP + +S P P+ P P P P+ + Sbjct: 642 -QKALPPPPASIPPPPPLPSGLGSLSPAPP-MPPVSAGPPLPPPPPPPPPLPPPSS--AG 697 Query: 438 PPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPSSG 484 PPPPPPPPP+ A PN P PP PPPP L PPP G Sbjct: 698 PPPPPPPPPLPNSPAPPN---------PGGPPPAPPPPGLAPPPPPG 735 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/101 (32%), Positives = 40/101 (39%), Gaps = 23/101 (22%) Query: 399 EHMVSQETSGFPSQRQNNPIMPQYPFPL-------PVFDMHNFPLRPPPPPPPPPVNMGW 451 E M S + P + P P P L P+ + P PPPPPPPPP+ Sbjct: 635 EGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP--- 691 Query: 452 ATPNMAAHPLLNLPYSLPPPPPPPPLPPPPSSGDSNSHFGP 492 P S PPPPPP PP P+S + GP Sbjct: 692 -------------PPSSAGPPPPPPPPPLPNSPAPPNPGGP 719 Score = 35.4 bits (80), Expect = 0.12 Identities = 33/92 (35%), Positives = 36/92 (39%), Gaps = 20/92 (21%) Query: 30 PSPGSAPVPGTQPPLQSFEGS---------PDAGQTVEVKPAGEQPLQPVLNAVAAGTPA 80 P P S P P PPL S GS AG + P PL P +AG P Sbjct: 647 PPPASIPPP---PPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPP---PSSAGPPP 700 Query: 81 PQPQPP-AESPACGDCVTSPGAAEPARAPDSL 111 P P PP SPA +PG PA P L Sbjct: 701 PPPPPPLPNSPA----PPNPGGPPPAPPPPGL 728 >gi|40807465 zinc finger protein 341 [Homo sapiens] Length = 847 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/90 (38%), Positives = 42/90 (46%), Gaps = 27/90 (30%) Query: 398 SEHMVSQETSGFPSQRQNNPIMPQYPFPLPV-FDMHNFP---LRPPPPPPPPPVNMGWAT 453 S+ ++ S F S Q MPQ P P+ +MH+ P +PPPPPPPPP Sbjct: 137 SDDVLMSAMSAFTSLDQP---MPQGPPPVQSSLNMHSVPSYLTQPPPPPPPPP------- 186 Query: 454 PNMAAHPLLNLPYSLPPPPPPPPLPPPPSS 483 LPPPPPP P PPPP S Sbjct: 187 -------------PLPPPPPPQPPPPPPQS 203 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/87 (39%), Positives = 43/87 (49%), Gaps = 16/87 (18%) Query: 398 SEHMVSQETSGFPSQRQNNPIMP-QYPFPLPVFDMHNFPLRPPPP--PPPPPVNMGWATP 454 ++H+ QE S+ QN P YP P RPPPP PP + A P Sbjct: 1486 ADHLPPQE-----SRLQNTSSRPGMYPPP--------GSYRPPPPMGKPPGSIVRPSAPP 1532 Query: 455 NMAAHPLLNLPYSLPPPPPPPPLPPPP 481 ++ P+ P +PPPPPPPPLPPPP Sbjct: 1533 ARSSVPVTRPPVPIPPPPPPPPLPPPP 1559 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 42/124 (33%) Query: 381 RYPRSCHGRPPP---------------QHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFP 425 RY S H PPP + +S + +SGF S R+ + Q Sbjct: 7 RYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQ--- 63 Query: 426 LPVFDMHNFPLR--------PPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPL 477 + MH ++ PPPP PPPPV G + PPPPP+ Sbjct: 64 --LQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQ--------------PPPPPM 107 Query: 478 PPPP 481 PPPP Sbjct: 108 PPPP 111 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 11/89 (12%) Query: 394 HFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWAT 453 H ++ + ++ + F Q N M P P P PP P PPPV Sbjct: 488 HMKATQSYLQEKVNSF--QNMKNQYMGNMSMPPPFVPYSQMP--PPLPTMPPPV-----L 538 Query: 454 PNMAAHPLLN--LPYSLPPPPPPPPLPPP 480 P P++ LP ++PPP PPP+ PP Sbjct: 539 PPSLPPPVMPPALPATVPPPGMPPPVMPP 567 Score = 38.9 bits (89), Expect = 0.011 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 9/64 (14%) Query: 438 PPPPPPPPPVNMGWATPNMAAHPLLN---------LPYSLPPPPPPPPLPPPPSSGDSNS 488 PPP PPPP + + H +L+ +P L PP PP+PP S S Sbjct: 104 PPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQS 163 Query: 489 HFGP 492 + P Sbjct: 164 YMPP 167 Score = 38.9 bits (89), Expect = 0.011 Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 9/84 (10%) Query: 417 PIMP--QYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLL--NLPYSLPPPP 472 P +P Q P PLP P PPP PP + P M P++ +LP S+PPP Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-PVMPPSLPTSVPPPG 577 Query: 473 PPP----PLPPPPSSGDSNSHFGP 492 PP PPP S S GP Sbjct: 578 MPPSLSSAGPPPVLPPPSLSSAGP 601 Score = 35.8 bits (81), Expect = 0.092 Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 36/84 (42%) Query: 438 PPPPPPPPPVNM-------GWATPNMAAHP------------LLNL-------------- 464 PPP PPPPPV + G+++ A P L L Sbjct: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75 Query: 465 --PYSLPPPP-PPPPLPPPPSSGD 485 P+ LPPPP PPPP+ P GD Sbjct: 76 LQPHHLPPPPLPPPPVMPGGGYGD 99 Score = 35.4 bits (80), Expect = 0.12 Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 10/74 (13%) Query: 425 PLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNL---PYSLPPPPPPPPLPP-- 479 P PV + PPP PPP A P + P L+ P +PPP P +PP Sbjct: 587 PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQL 646 Query: 480 -----PPSSGDSNS 488 PP+S +S Sbjct: 647 TAAPVPPASSSQSS 660 Score = 35.0 bits (79), Expect = 0.16 Identities = 36/142 (25%), Positives = 50/142 (35%), Gaps = 9/142 (6%) Query: 32 PGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQPPAESPA 91 P S P PG P L S G P + AG P+ P + + P P PP S Sbjct: 570 PTSVPPPGMPPSLSS-AGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSAT 628 Query: 92 CGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDS--DSSSSSSSSSSSSSSSSSSCISL 149 + PG P P L + S S++ + + + S S+ Sbjct: 629 PPPGIPPPGV--PQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYH 686 Query: 150 PPVLSDGDDDLQIEKENKNFPL 171 PP+ S G E+ N PL Sbjct: 687 PPLQSAGPS----EQVNSKAPL 704 Score = 33.9 bits (76), Expect = 0.35 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 8/49 (16%) Query: 435 PLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPSS 483 P+ PP PPV G P ++ +PPP PPP PP SS Sbjct: 140 PMELESPPESPPVPPGSYMPPSQSY--------MPPPQPPPSYYPPTSS 180 Score = 33.5 bits (75), Expect = 0.46 Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 11/107 (10%) Query: 79 PAPQPQPPAESPACGDCVTSPGAAEPARAPDS---LETSDSDSDSDSETDSDSSSSSSSS 135 P PQP P P P P+++P S L + S S S S + S S S S Sbjct: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYL 225 Query: 136 SSSSSS--------SSSSCISLPPVLSDGDDDLQIEKENKNFPLKTK 174 SS +S S S ++ PP + + +++E K K Sbjct: 226 PSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNK 272 Score = 32.3 bits (72), Expect = 1.0 Identities = 39/165 (23%), Positives = 56/165 (33%), Gaps = 44/165 (26%) Query: 353 QNWNAHSSASEHAKGYRNREFTRGFSRARYPRSCHGRPPPQHFYNSEHMVSQETSGFPSQ 412 +++ + ++H +R YP RPPP +V P Sbjct: 1477 KDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSA---PPA 1533 Query: 413 RQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPV---------NMGW------------ 451 R + P+ + P P+P P PPP PPPPPV W Sbjct: 1534 RSSVPVT-RPPVPIPP------PPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTN 1586 Query: 452 -----------ATPNMAAHPLLNLP--YSLPPPPPPPPLPPPPSS 483 T + + P+L P +S PPP P P+ PP S Sbjct: 1587 DEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMS 1631 Score = 31.2 bits (69), Expect = 2.3 Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 14/79 (17%) Query: 417 PIMPQYPFPLPVFDMHNFPLRPPPPPPPPPV---NMGWATPNMAAHPLLNL---PYSLPP 470 P++P P PV P PPP PPPV ++ + P P L+ P LPP Sbjct: 536 PVLPP-SLPPPVMPPA-LPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPP 593 Query: 471 P------PPPPPLPPPPSS 483 P PPP PP SS Sbjct: 594 PSLSSAGPPPVLPPPSLSS 612 Score = 30.4 bits (67), Expect = 3.9 Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 4/66 (6%) Query: 425 PLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYS----LPPPPPPPPLPPP 480 P PV + PPP PPP P + A P+ S +P P P LP P Sbjct: 615 PPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTP 674 Query: 481 PSSGDS 486 S G + Sbjct: 675 VSFGSA 680 >gi|90903231 huntingtin [Homo sapiens] Length = 3144 Score = 53.9 bits (128), Expect = 3e-07 Identities = 27/52 (51%), Positives = 30/52 (57%), Gaps = 5/52 (9%) Query: 438 PPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPSSGDSNSH 489 PPPPPPPPP + P A PLL P PPPPPPPP PP P+ + H Sbjct: 42 PPPPPPPPPPQLPQPPPQ--AQPLL--PQPQPPPPPPPP-PPGPAVAEEPLH 88 Score = 33.9 bits (76), Expect = 0.35 Identities = 22/65 (33%), Positives = 23/65 (35%), Gaps = 26/65 (40%) Query: 417 PIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPP 476 P PQ P P P PL P P PPPPP PPPPP P Sbjct: 48 PPPPQLPQPPPQAQ----PLLPQPQPPPPP----------------------PPPPPGPA 81 Query: 477 LPPPP 481 + P Sbjct: 82 VAEEP 86 Score = 30.4 bits (67), Expect = 3.9 Identities = 10/11 (90%), Positives = 10/11 (90%) Query: 469 PPPPPPPPLPP 479 PPPPPPPP PP Sbjct: 41 PPPPPPPPPPP 51 Score = 30.4 bits (67), Expect = 3.9 Identities = 10/11 (90%), Positives = 10/11 (90%) Query: 470 PPPPPPPLPPP 480 PPPPPPP PPP Sbjct: 41 PPPPPPPPPPP 51 Score = 30.4 bits (67), Expect = 3.9 Identities = 10/11 (90%), Positives = 10/11 (90%) Query: 471 PPPPPPLPPPP 481 PPPPPP PPPP Sbjct: 41 PPPPPPPPPPP 51 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 53.9 bits (128), Expect = 3e-07 Identities = 24/47 (51%), Positives = 26/47 (55%) Query: 435 PLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPP 481 PL PPPPP PP + N P + P PPPPPPPP PPPP Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPP 571 Score = 51.2 bits (121), Expect = 2e-06 Identities = 31/73 (42%), Positives = 34/73 (46%), Gaps = 10/73 (13%) Query: 406 TSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLP 465 +S P QN P+ P P P P P PPPPPPPPP G A + A PL Sbjct: 536 SSDTPETVQNGPVTPPMPPPPPPPP----PPPPPPPPPPPPPLPGPAAETVPAPPL---- 587 Query: 466 YSLPPPPPPPPLP 478 PP P PPLP Sbjct: 588 --APPLPSAPPLP 598 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/64 (40%), Positives = 28/64 (43%), Gaps = 18/64 (28%) Query: 417 PIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPP 476 P+ P P V + P PPPPPPPPP P PPPPPPPP Sbjct: 532 PLPPSSDTPETVQNGPVTPPMPPPPPPPPP------------------PPPPPPPPPPPP 573 Query: 477 LPPP 480 LP P Sbjct: 574 LPGP 577 Score = 38.1 bits (87), Expect = 0.018 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 3/95 (3%) Query: 22 GVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAP 81 G GP + S P+P PPL +P+ Q V P P P P P Sbjct: 511 GNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTP--PMPPPPPPPPPPPPPPPP 568 Query: 82 QPQPPAESPACGDCVTSPGAAEPARAPDSLETSDS 116 P PP PA + V +P A P + L + S Sbjct: 569 PPPPPLPGPA-AETVPAPPLAPPLPSAPPLPGTSS 602 Score = 30.8 bits (68), Expect = 3.0 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 460 PLLNLPYSLPPPPPPPPLPP 479 P + S P PPPPPPLPP Sbjct: 516 PTMGAASSGPLPPPPPPLPP 535 >gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 14/100 (14%) Query: 390 PPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNM 449 PPP H + S +N P P PVF + P PPPPPPP+ Sbjct: 281 PPPMHGAGDAKPIPTCISSATGLIENRPQSPATG-RTPVF------VSPTPPPPPPPLPS 333 Query: 450 GWATPNMAAHPLLNLPYSLPPPPPP-------PPLPPPPS 482 +T ++ A P +PPPPPP P +PPPP+ Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA 373 Score = 50.4 bits (119), Expect = 4e-06 Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 9/83 (10%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPP-----PPPVNMGWATPNMAAHPL-LN 463 P+ P +P P PL + P PP PP PP + HPL Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418 Query: 464 LPYSLPPPPPPPPLPPP---PSS 483 LPPPPPPPPLPPP PSS Sbjct: 419 EVQGLPPPPPPPPLPPPGIRPSS 441 Score = 38.9 bits (89), Expect = 0.011 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 16/107 (14%) Query: 383 PRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPF-PLPVFDMHNFPLRPPPP 441 P H PPP + P + P+ P PLP ++ P PPPP Sbjct: 379 PGVLHPAPPP--------IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLP-PPPPP 429 Query: 442 PPPPPVNMGWATP---NMAAHPLLNL---PYSLPPPPPPPPLPPPPS 482 PP PP + ++P AHP L P + P P P P PPS Sbjct: 430 PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476 Score = 36.6 bits (83), Expect = 0.054 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 14/67 (20%) Query: 436 LRPPPPPPPPPVN-MGWATP-----NMAAHPLLNLPYS--------LPPPPPPPPLPPPP 481 +RP PPPPPP++ G A P + A + N P S P PPPP PP P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 482 SSGDSNS 488 S+ ++S Sbjct: 333 SALSTSS 339 Score = 36.6 bits (83), Expect = 0.054 Identities = 26/82 (31%), Positives = 29/82 (35%), Gaps = 35/82 (42%) Query: 435 PLRPPPPPP--------PPPVNMGWAT---------PNMAAHPLLNLPYSLPPPP----- 472 P PPPPPP P P + AT P P+ P PPPP Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334 Query: 473 -------------PPPPLPPPP 481 PPPP+PPPP Sbjct: 335 LSTSSLRASMTSTPPPPVPPPP 356 Score = 30.4 bits (67), Expect = 3.9 Identities = 29/98 (29%), Positives = 37/98 (37%), Gaps = 15/98 (15%) Query: 27 PAAPSPGSAPVPGTQP----PLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTP--- 79 P+ P +APV T P P +G P + P G +P PV A P Sbjct: 396 PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGL 455 Query: 80 ------APQPQPPAESPACGDCVTSPGAAEPARAPDSL 111 AP P P P+ V A+EP R P +L Sbjct: 456 HPTPSTAPGPHVPLMPPSPPSQVIP--ASEPKRHPSTL 491 >gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 14/100 (14%) Query: 390 PPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNM 449 PPP H + S +N P P PVF + P PPPPPPP+ Sbjct: 281 PPPMHGAGDAKPIPTCISSATGLIENRPQSPATG-RTPVF------VSPTPPPPPPPLPS 333 Query: 450 GWATPNMAAHPLLNLPYSLPPPPPP-------PPLPPPPS 482 +T ++ A P +PPPPPP P +PPPP+ Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA 373 Score = 50.4 bits (119), Expect = 4e-06 Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 9/83 (10%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPP-----PPPVNMGWATPNMAAHPL-LN 463 P+ P +P P PL + P PP PP PP + HPL Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418 Query: 464 LPYSLPPPPPPPPLPPP---PSS 483 LPPPPPPPPLPPP PSS Sbjct: 419 EVQGLPPPPPPPPLPPPGIRPSS 441 Score = 38.9 bits (89), Expect = 0.011 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 16/107 (14%) Query: 383 PRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPF-PLPVFDMHNFPLRPPPP 441 P H PPP + P + P+ P PLP ++ P PPPP Sbjct: 379 PGVLHPAPPP--------IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLP-PPPPP 429 Query: 442 PPPPPVNMGWATP---NMAAHPLLNL---PYSLPPPPPPPPLPPPPS 482 PP PP + ++P AHP L P + P P P P PPS Sbjct: 430 PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476 Score = 36.6 bits (83), Expect = 0.054 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 14/67 (20%) Query: 436 LRPPPPPPPPPVN-MGWATP-----NMAAHPLLNLPYS--------LPPPPPPPPLPPPP 481 +RP PPPPPP++ G A P + A + N P S P PPPP PP P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 482 SSGDSNS 488 S+ ++S Sbjct: 333 SALSTSS 339 Score = 36.6 bits (83), Expect = 0.054 Identities = 26/82 (31%), Positives = 29/82 (35%), Gaps = 35/82 (42%) Query: 435 PLRPPPPPP--------PPPVNMGWAT---------PNMAAHPLLNLPYSLPPPP----- 472 P PPPPPP P P + AT P P+ P PPPP Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334 Query: 473 -------------PPPPLPPPP 481 PPPP+PPPP Sbjct: 335 LSTSSLRASMTSTPPPPVPPPP 356 Score = 30.4 bits (67), Expect = 3.9 Identities = 29/98 (29%), Positives = 37/98 (37%), Gaps = 15/98 (15%) Query: 27 PAAPSPGSAPVPGTQP----PLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTP--- 79 P+ P +APV T P P +G P + P G +P PV A P Sbjct: 396 PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGL 455 Query: 80 ------APQPQPPAESPACGDCVTSPGAAEPARAPDSL 111 AP P P P+ V A+EP R P +L Sbjct: 456 HPTPSTAPGPHVPLMPPSPPSQVIP--ASEPKRHPSTL 491 >gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 14/100 (14%) Query: 390 PPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNM 449 PPP H + S +N P P PVF + P PPPPPPP+ Sbjct: 281 PPPMHGAGDAKPIPTCISSATGLIENRPQSPATG-RTPVF------VSPTPPPPPPPLPS 333 Query: 450 GWATPNMAAHPLLNLPYSLPPPPPP-------PPLPPPPS 482 +T ++ A P +PPPPPP P +PPPP+ Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA 373 Score = 50.4 bits (119), Expect = 4e-06 Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 9/83 (10%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPP-----PPPVNMGWATPNMAAHPL-LN 463 P+ P +P P PL + P PP PP PP + HPL Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418 Query: 464 LPYSLPPPPPPPPLPPP---PSS 483 LPPPPPPPPLPPP PSS Sbjct: 419 EVQGLPPPPPPPPLPPPGIRPSS 441 Score = 38.9 bits (89), Expect = 0.011 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 16/107 (14%) Query: 383 PRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPF-PLPVFDMHNFPLRPPPP 441 P H PPP + P + P+ P PLP ++ P PPPP Sbjct: 379 PGVLHPAPPP--------IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLP-PPPPP 429 Query: 442 PPPPPVNMGWATP---NMAAHPLLNL---PYSLPPPPPPPPLPPPPS 482 PP PP + ++P AHP L P + P P P P PPS Sbjct: 430 PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476 Score = 36.6 bits (83), Expect = 0.054 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 14/67 (20%) Query: 436 LRPPPPPPPPPVN-MGWATP-----NMAAHPLLNLPYS--------LPPPPPPPPLPPPP 481 +RP PPPPPP++ G A P + A + N P S P PPPP PP P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 482 SSGDSNS 488 S+ ++S Sbjct: 333 SALSTSS 339 Score = 36.6 bits (83), Expect = 0.054 Identities = 26/82 (31%), Positives = 29/82 (35%), Gaps = 35/82 (42%) Query: 435 PLRPPPPPP--------PPPVNMGWAT---------PNMAAHPLLNLPYSLPPPP----- 472 P PPPPPP P P + AT P P+ P PPPP Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334 Query: 473 -------------PPPPLPPPP 481 PPPP+PPPP Sbjct: 335 LSTSSLRASMTSTPPPPVPPPP 356 Score = 30.4 bits (67), Expect = 3.9 Identities = 29/98 (29%), Positives = 37/98 (37%), Gaps = 15/98 (15%) Query: 27 PAAPSPGSAPVPGTQP----PLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTP--- 79 P+ P +APV T P P +G P + P G +P PV A P Sbjct: 396 PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGL 455 Query: 80 ------APQPQPPAESPACGDCVTSPGAAEPARAPDSL 111 AP P P P+ V A+EP R P +L Sbjct: 456 HPTPSTAPGPHVPLMPPSPPSQVIP--ASEPKRHPSTL 491 >gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 14/100 (14%) Query: 390 PPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNM 449 PPP H + S +N P P PVF + P PPPPPPP+ Sbjct: 281 PPPMHGAGDAKPIPTCISSATGLIENRPQSPATG-RTPVF------VSPTPPPPPPPLPS 333 Query: 450 GWATPNMAAHPLLNLPYSLPPPPPP-------PPLPPPPS 482 +T ++ A P +PPPPPP P +PPPP+ Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA 373 Score = 50.4 bits (119), Expect = 4e-06 Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 9/83 (10%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPP-----PPPVNMGWATPNMAAHPL-LN 463 P+ P +P P PL + P PP PP PP + HPL Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418 Query: 464 LPYSLPPPPPPPPLPPP---PSS 483 LPPPPPPPPLPPP PSS Sbjct: 419 EVQGLPPPPPPPPLPPPGIRPSS 441 Score = 38.9 bits (89), Expect = 0.011 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 16/107 (14%) Query: 383 PRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPF-PLPVFDMHNFPLRPPPP 441 P H PPP + P + P+ P PLP ++ P PPPP Sbjct: 379 PGVLHPAPPP--------IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLP-PPPPP 429 Query: 442 PPPPPVNMGWATP---NMAAHPLLNL---PYSLPPPPPPPPLPPPPS 482 PP PP + ++P AHP L P + P P P P PPS Sbjct: 430 PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476 Score = 36.6 bits (83), Expect = 0.054 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 14/67 (20%) Query: 436 LRPPPPPPPPPVN-MGWATP-----NMAAHPLLNLPYS--------LPPPPPPPPLPPPP 481 +RP PPPPPP++ G A P + A + N P S P PPPP PP P Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332 Query: 482 SSGDSNS 488 S+ ++S Sbjct: 333 SALSTSS 339 Score = 36.6 bits (83), Expect = 0.054 Identities = 26/82 (31%), Positives = 29/82 (35%), Gaps = 35/82 (42%) Query: 435 PLRPPPPPP--------PPPVNMGWAT---------PNMAAHPLLNLPYSLPPPP----- 472 P PPPPPP P P + AT P P+ P PPPP Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334 Query: 473 -------------PPPPLPPPP 481 PPPP+PPPP Sbjct: 335 LSTSSLRASMTSTPPPPVPPPP 356 Score = 30.4 bits (67), Expect = 3.9 Identities = 29/98 (29%), Positives = 37/98 (37%), Gaps = 15/98 (15%) Query: 27 PAAPSPGSAPVPGTQP----PLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTP--- 79 P+ P +APV T P P +G P + P G +P PV A P Sbjct: 396 PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGL 455 Query: 80 ------APQPQPPAESPACGDCVTSPGAAEPARAPDSL 111 AP P P P+ V A+EP R P +L Sbjct: 456 HPTPSTAPGPHVPLMPPSPPSQVIP--ASEPKRHPSTL 491 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 53.5 bits (127), Expect = 4e-07 Identities = 32/71 (45%), Positives = 36/71 (50%), Gaps = 8/71 (11%) Query: 420 PQYPFPLPVFDMHNFPLRPPPP-----PPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPP 474 P P PL + P PPPP PPPPP G + P P P +PPPPPP Sbjct: 341 PLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGP-PMPPPPPP 399 Query: 475 PPLPPPPSSGD 485 P PPPPSSG+ Sbjct: 400 P--PPPPSSGN 408 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 10/57 (17%) Query: 435 PLRPPPPP-------PPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPSSG 484 PL PPPPP P PP+ G + PL +P + PPPP P PPPP G Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGG---NKGRSGPLPPVPLGIAPPPPTPRGPPPPGRG 365 Score = 32.7 bits (73), Expect = 0.78 Identities = 28/92 (30%), Positives = 33/92 (35%), Gaps = 8/92 (8%) Query: 22 GVGEGPAAPSPGSAPVP-GTQPPLQSFEGSPDAGQTVEVKP----AGEQPLQPVLNAVAA 76 G +G + P P PVP G PP + G P G+ P G P A Sbjct: 333 GGNKGRSGPLP---PVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAG 389 Query: 77 GTPAPQPQPPAESPACGDCVTSPGAAEPARAP 108 G P P P PP P +P PA P Sbjct: 390 GPPMPPPPPPPPPPPSSGNGPAPPPLPPALVP 421 Score = 31.2 bits (69), Expect = 2.3 Identities = 25/80 (31%), Positives = 28/80 (35%), Gaps = 12/80 (15%) Query: 26 GPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQP 85 GP P P + G PP G P P P P + PAP P P Sbjct: 366 GPPPPPPPATGRSGPLPPPPPGAGGP---------PMPPPPPPPPPPPSSGNGPAPPPLP 416 Query: 86 PAESPACGDCVTSPGAAEPA 105 PA PA G +PG A Sbjct: 417 PALVPAGG---LAPGGGRGA 433 Score = 29.6 bits (65), Expect = 6.6 Identities = 14/30 (46%), Positives = 15/30 (50%), Gaps = 6/30 (20%) Query: 469 PPPPPPPP------LPPPPSSGDSNSHFGP 492 P PPPPPP LP PP G + GP Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGP 341 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 53.1 bits (126), Expect = 6e-07 Identities = 32/84 (38%), Positives = 36/84 (42%), Gaps = 15/84 (17%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLP 469 PS P +P P P P + PPPPPPPPP G P P Sbjct: 559 PSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPP--------------P 604 Query: 470 PPPPPPPLPPPPSS-GDSNSHFGP 492 PPPPPPP PP + G +S GP Sbjct: 605 PPPPPPPPGGPPDALGRRDSELGP 628 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/59 (45%), Positives = 29/59 (49%), Gaps = 13/59 (22%) Query: 438 PPPPPPPPPVNMGWATPNMA---AHPLLN---------LPYSLPPPPPPPPLPPPPSSG 484 PPPPPP P + P A A PL LP LPPPPPPPP PPP + G Sbjct: 542 PPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPP-PPPGTDG 599 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 26/78 (33%) Query: 408 GFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYS 467 G PS ++ P P PLP P PPP PP+ P +LP Sbjct: 550 GLPSPQEAPPSAPPQAPPLP---------GSPEPPPAPPL------PG-------DLPPP 587 Query: 468 LPPPPPPP----PLPPPP 481 PPPPPPP P+PPPP Sbjct: 588 PPPPPPPPGTDGPVPPPP 605 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 11/81 (13%) Query: 28 AAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQPPA 87 A PS G AP PG + + SPD E P P P L + + AP PP Sbjct: 509 ATPSGGDAPTPG----VPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQ 564 Query: 88 ESPACGDCVTSPGAAEPARAP 108 P PG+ EP AP Sbjct: 565 APPL-------PGSPEPPPAP 578 Score = 31.2 bits (69), Expect = 2.3 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 6/47 (12%) Query: 443 PPPPVNMGWATPNMA--AHPLLNLPYSLPPPPPP-PPLPPPPSSGDS 486 P P V G +P++A A P P + PPPPPP P LP P + S Sbjct: 517 PTPGVPTGSPSPDLAPAAEPA---PGAAPPPPPPLPGLPSPQEAPPS 560 Score = 29.3 bits (64), Expect = 8.6 Identities = 26/93 (27%), Positives = 28/93 (30%), Gaps = 18/93 (19%) Query: 27 PAAPSPGSAP--VPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQ 84 P PSP AP P PPL P A P P P P P P Sbjct: 549 PGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPP 608 Query: 85 PPAESPACGDCVTSPGAAEPARAPDSLETSDSD 117 PP P PD+L DS+ Sbjct: 609 PP----------------PPGGPPDALGRRDSE 625 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 52.4 bits (124), Expect = 9e-07 Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 19/75 (25%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLP 469 P Q + +P P P P + + PPPPPPP LP +P Sbjct: 321 PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPP-------------------LPNQVP 361 Query: 470 PPPPPPPLPPPPSSG 484 PPPPPPP PP P+SG Sbjct: 362 PPPPPPPAPPLPASG 376 Score = 50.4 bits (119), Expect = 4e-06 Identities = 28/64 (43%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Query: 417 PIMPQYPFPLPVFDMHNFPLRPPPP--PPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPP 474 P+ P P PLP PPPP PPPPP+ P PL N PPPPP Sbjct: 310 PLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPA 369 Query: 475 PPLP 478 PPLP Sbjct: 370 PPLP 373 Score = 48.9 bits (115), Expect = 1e-05 Identities = 28/58 (48%), Positives = 32/58 (55%), Gaps = 14/58 (24%) Query: 435 PLRPPPPPPPPPVNMGWATPNMAAHPLLN------LPYSLPPPPPPPP-----LPPPP 481 PL PPPPPP PP G A ++A P LP + PPPPPPPP +PPPP Sbjct: 310 PLAPPPPPPLPP---GPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPP 364 Score = 29.6 bits (65), Expect = 6.6 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMA 457 P P P P PLP + P PPPPP PP G+ +M+ Sbjct: 340 PPLPSTGPPPPPPPPPLP----NQVPPPPPPPPAPPLPASGFFLASMS 383 Score = 29.3 bits (64), Expect = 8.6 Identities = 34/121 (28%), Positives = 47/121 (38%), Gaps = 17/121 (14%) Query: 26 GPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQP 85 GPA S P PG PP P G P P P+ N V P P P P Sbjct: 322 GPAQASVALPPPPGPPPP----PPLPSTG------PPPPPPPPPLPNQV----PPPPPPP 367 Query: 86 PAES-PACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 PA PA G + S +E R L + + + + + +S S ++ +S+S Sbjct: 368 PAPPLPASGFFLAS--MSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSAS 425 Query: 145 S 145 S Sbjct: 426 S 426 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 52.4 bits (124), Expect = 9e-07 Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 19/75 (25%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLP 469 P Q + +P P P P + + PPPPPPP LP +P Sbjct: 321 PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPP-------------------LPNQVP 361 Query: 470 PPPPPPPLPPPPSSG 484 PPPPPPP PP P+SG Sbjct: 362 PPPPPPPAPPLPASG 376 Score = 50.4 bits (119), Expect = 4e-06 Identities = 28/64 (43%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Query: 417 PIMPQYPFPLPVFDMHNFPLRPPPP--PPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPP 474 P+ P P PLP PPPP PPPPP+ P PL N PPPPP Sbjct: 310 PLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPA 369 Query: 475 PPLP 478 PPLP Sbjct: 370 PPLP 373 Score = 48.9 bits (115), Expect = 1e-05 Identities = 28/58 (48%), Positives = 32/58 (55%), Gaps = 14/58 (24%) Query: 435 PLRPPPPPPPPPVNMGWATPNMAAHPLLN------LPYSLPPPPPPPP-----LPPPP 481 PL PPPPPP PP G A ++A P LP + PPPPPPPP +PPPP Sbjct: 310 PLAPPPPPPLPP---GPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPP 364 Score = 29.6 bits (65), Expect = 6.6 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMA 457 P P P P PLP + P PPPPP PP G+ +M+ Sbjct: 340 PPLPSTGPPPPPPPPPLP----NQVPPPPPPPPAPPLPASGFFLASMS 383 Score = 29.3 bits (64), Expect = 8.6 Identities = 34/121 (28%), Positives = 47/121 (38%), Gaps = 17/121 (14%) Query: 26 GPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQP 85 GPA S P PG PP P G P P P+ N V P P P P Sbjct: 322 GPAQASVALPPPPGPPPP----PPLPSTG------PPPPPPPPPLPNQV----PPPPPPP 367 Query: 86 PAES-PACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 PA PA G + S +E R L + + + + + +S S ++ +S+S Sbjct: 368 PAPPLPASGFFLAS--MSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSAS 425 Query: 145 S 145 S Sbjct: 426 S 426 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 52.0 bits (123), Expect = 1e-06 Identities = 38/98 (38%), Positives = 50/98 (51%), Gaps = 5/98 (5%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 A SPA +S ++ + + S +S S S S S + S SSSSSSSSSSSSSSSSSS Sbjct: 2609 AASPA-----SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663 Query: 147 ISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLNELPS 184 S S D+D +++ P T LP+ Sbjct: 2664 SSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPT 2701 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/51 (60%), Positives = 34/51 (66%) Query: 98 SPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCIS 148 S AA PA + S +S S S S S + S SSSSSSSSSSSSSSSSSS S Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656 Score = 49.7 bits (117), Expect = 6e-06 Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 4/81 (4%) Query: 72 NAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSS 131 N AA + A P + S + +S ++ + + S +S S S S S + S SSSS Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660 Query: 132 SSSSSSSSSSSS----SSCIS 148 SSSSSSSSSSS+ SSC S Sbjct: 2661 SSSSSSSSSSSTTDEDSSCSS 2681 Score = 49.7 bits (117), Expect = 6e-06 Identities = 31/73 (42%), Positives = 40/73 (54%) Query: 86 PAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 PA S + +S ++ + + S +S S S S S + S SSSSSSSSSSSSSSSSSS Sbjct: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671 Query: 146 CISLPPVLSDGDD 158 S D+ Sbjct: 2672 TTDEDSSCSSDDE 2684 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/74 (44%), Positives = 42/74 (56%), Gaps = 7/74 (9%) Query: 75 AAGTPAPQ-PQPPAESPACGDCVTSPGAA---EPARAPDSLETSDSDSDSDSETDSDSSS 130 AAG+ P+ P P A GD PG E + P S + + ++ D E++S SSS Sbjct: 2507 AAGSSEPKAPWPKATD---GDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSS 2563 Query: 131 SSSSSSSSSSSSSS 144 SS SSSSSSSSSSS Sbjct: 2564 SSGSSSSSSSSSSS 2577 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/57 (52%), Positives = 34/57 (59%) Query: 92 CGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCIS 148 CG + AA A + +S S S S S + S SSSSSSSSSSSSSSSSSS S Sbjct: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/56 (51%), Positives = 32/56 (57%) Query: 93 GDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCIS 148 G C T A + + S S S S S + S SSSSSSSSSSSSSSSSSS S Sbjct: 2593 GGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/56 (50%), Positives = 31/56 (55%) Query: 93 GDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCIS 148 GD G + A + S S S S + S SSSSSSSSSSSSSSSSSS S Sbjct: 2591 GDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646 Score = 38.1 bits (87), Expect = 0.018 Identities = 26/56 (46%), Positives = 30/56 (53%) Query: 93 GDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCIS 148 GD G R + + + S S + S SSSSSSSSSSSSSSSSSS S Sbjct: 2587 GDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642 Score = 37.4 bits (85), Expect = 0.032 Identities = 24/84 (28%), Positives = 39/84 (46%) Query: 73 AVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSS 132 A + + + + S + +S ++ + + S +S S S S S + S SSSSS Sbjct: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668 Query: 133 SSSSSSSSSSSSSCISLPPVLSDG 156 SSS++ SS SS P + G Sbjct: 2669 SSSTTDEDSSCSSDDEAAPAPTAG 2692 Score = 31.2 bits (69), Expect = 2.3 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 7/127 (5%) Query: 26 GPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQP 85 G P+ GS+ P + + + G + + +G P P + A + Sbjct: 2502 GSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGN-PKSP--DKAQAEQDGAEESE 2558 Query: 86 PAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETD----SDSSSSSSSSSSSSSS 141 + S + G +S ++ + E D + D T S +SS ++S +SSSSS Sbjct: 2559 SSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSS 2618 Query: 142 SSSSCIS 148 SSSS S Sbjct: 2619 SSSSSSS 2625 Score = 29.3 bits (64), Expect = 8.6 Identities = 11/17 (64%), Positives = 11/17 (64%) Query: 465 PYSLPPPPPPPPLPPPP 481 P LPPPP PP PP P Sbjct: 332 PSPLPPPPAPPKGPPAP 348 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/57 (29%), Positives = 23/57 (40%), Gaps = 8/57 (14%) Query: 34 SAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQPVLNAVAAGTPAPQPQPPAESP 90 +AP P P Q+ + Q + +P+ P TPAPQPQ P P Sbjct: 2685 AAPAPTAGPSAQAALPTKATKQAGKARPSAHSP--------GKKTPAPQPQAPPPQP 2733 >gi|145309324 FH2 domain containing 1 [Homo sapiens] Length = 1143 Score = 52.0 bits (123), Expect = 1e-06 Identities = 27/64 (42%), Positives = 31/64 (48%), Gaps = 12/64 (18%) Query: 435 PLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPP-----PPLPPPPSSGDSNSH 489 P PPPPPPPPP + P + P S PPPPPP PP+PPPP +H Sbjct: 32 PAPPPPPPPPPP-----SPPCSCSRE--ECPSSPPPPPPPPLPGEPPIPPPPPGLPPTTH 84 Query: 490 FGPY 493 Y Sbjct: 85 MNGY 88 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/75 (36%), Positives = 29/75 (38%), Gaps = 19/75 (25%) Query: 417 PIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPP 476 P P P P P PPPPPPPP LP PP PPPPP Sbjct: 37 PPPPPPPSPPCSCSREECPSSPPPPPPPP------------------LP-GEPPIPPPPP 77 Query: 477 LPPPPSSGDSNSHFG 491 PP + + SH G Sbjct: 78 GLPPTTHMNGYSHLG 92 Score = 37.0 bits (84), Expect = 0.041 Identities = 15/28 (53%), Positives = 18/28 (64%) Query: 455 NMAAHPLLNLPYSLPPPPPPPPLPPPPS 482 N+A P + + PP PPPPP PPPPS Sbjct: 17 NIATAPGFMIGQTPPPAPPPPPPPPPPS 44 Score = 34.7 bits (78), Expect = 0.20 Identities = 13/19 (68%), Positives = 13/19 (68%) Query: 465 PYSLPPPPPPPPLPPPPSS 483 P PPPPPPPP P PP S Sbjct: 30 PPPAPPPPPPPPPPSPPCS 48 >gi|149944526 additional sex combs like 3 [Homo sapiens] Length = 2248 Score = 52.0 bits (123), Expect = 1e-06 Identities = 25/43 (58%), Positives = 25/43 (58%), Gaps = 16/43 (37%) Query: 438 PPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPP 480 PPPPPPPPP P L LP PPPPPPPPLPPP Sbjct: 2018 PPPPPPPPP-------------PPLALP---PPPPPPPPLPPP 2044 Score = 49.3 bits (116), Expect = 8e-06 Identities = 22/44 (50%), Positives = 23/44 (52%), Gaps = 18/44 (40%) Query: 438 PPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPP 481 PPPPPPPPP P +LPPPPPPPP PPP Sbjct: 2019 PPPPPPPPP------------------PLALPPPPPPPPPLPPP 2044 Score = 35.8 bits (81), Expect = 0.092 Identities = 14/23 (60%), Positives = 15/23 (65%) Query: 458 AHPLLNLPYSLPPPPPPPPLPPP 480 AH + N PPPPPPPP PPP Sbjct: 2006 AHTMPNKALVHPPPPPPPPPPPP 2028 Score = 33.9 bits (76), Expect = 0.35 Identities = 19/51 (37%), Positives = 20/51 (39%), Gaps = 23/51 (45%) Query: 432 HNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPP-PLPPPP 481 H P + PPPPP PPPPPPP LPPPP Sbjct: 2007 HTMPNKALVHPPPPP----------------------PPPPPPPLALPPPP 2035 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 50.4 bits (119), Expect = 4e-06 Identities = 28/46 (60%), Positives = 35/46 (76%) Query: 114 SDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDD 159 +DSD ++DS +DS+SSSSSSSSSSSSSSSSSS S S D++ Sbjct: 1021 ADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEE 1066 Score = 49.7 bits (117), Expect = 6e-06 Identities = 25/55 (45%), Positives = 31/55 (56%), Gaps = 9/55 (16%) Query: 435 PLRPPPPPPPPP--------VNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPP 481 P +PPPPPPPPP + +G+ P+ A+ L P PPP PPP PPPP Sbjct: 601 PQQPPPPPPPPPPPPPYLASLPLGY-PPHQPAYLLPPRPDGPPPPEYPPPPPPPP 654 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/53 (54%), Positives = 37/53 (69%) Query: 93 GDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 G+ S +++ + DS +DS SDS+S + S SSSSSSSSSSSSSSSSSS Sbjct: 1006 GEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSS 1058 Score = 47.0 bits (110), Expect = 4e-05 Identities = 26/46 (56%), Positives = 34/46 (73%) Query: 114 SDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDD 159 SD ++DS S+++S SSSSSSSSSSSSSSSSSS S D +++ Sbjct: 1023 SDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEE 1068 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/33 (75%), Positives = 27/33 (81%) Query: 113 TSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 TSDS+S S S + S SSSSSSSSSSSSSS SSS Sbjct: 1030 TSDSESSSSSSSSSSSSSSSSSSSSSSSSESSS 1062 Score = 45.1 bits (105), Expect = 2e-04 Identities = 26/55 (47%), Positives = 34/55 (61%) Query: 116 SDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFP 170 +DSD ++++ SDS SSSSSSSSSSSSSSSS S +D + E+ P Sbjct: 1021 ADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALP 1075 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/93 (38%), Positives = 43/93 (46%), Gaps = 13/93 (13%) Query: 112 ETSDSDS------DSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKE 165 E SDS S DSD E DS S S SSSSSSSSSSSSSS S S E+E Sbjct: 1009 EESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEE 1068 Query: 166 NKNFPLKTKDELLLNELPSVEELTIILPEDIEL 198 + L + P E+ + P +E+ Sbjct: 1069 ERPAALPSAS-------PPPREVPVPTPAPVEV 1094 Score = 43.9 bits (102), Expect = 3e-04 Identities = 25/37 (67%), Positives = 27/37 (72%) Query: 109 DSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 D S SDS+S S + S SSSSSSSSSSSSSSSS S Sbjct: 1024 DGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSES 1060 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/54 (48%), Positives = 28/54 (51%), Gaps = 10/54 (18%) Query: 438 PPPPPPPPPVNMGWATPNMAAHPLLNLP----YSLPP----PPPP--PPLPPPP 481 PP PPPPP P +A+ PL P Y LPP PPPP PP PPPP Sbjct: 600 PPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPP 653 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/35 (65%), Positives = 25/35 (71%) Query: 109 DSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSS 143 DS S+S S S S + S SSSSSSSSSSSS SSS Sbjct: 1028 DSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSS 1062 Score = 38.5 bits (88), Expect = 0.014 Identities = 18/43 (41%), Positives = 18/43 (41%), Gaps = 20/43 (46%) Query: 439 PPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPP 481 PPP P PP PPPPPPPP PPPP Sbjct: 594 PPPAPTPPQQ--------------------PPPPPPPPPPPPP 616 Score = 36.2 bits (82), Expect = 0.070 Identities = 44/192 (22%), Positives = 71/192 (36%), Gaps = 20/192 (10%) Query: 295 KGSDASWKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSEFNEPGEDFTEVHQN 354 +G +AS ++ E E DDE+++E + R+++ +K+ + E E + + Sbjct: 964 EGEEASQESSSEKDEE-----DDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCS 1018 Query: 355 WNAHSSASEHAKGYRNREFTRGFSRARYPRSCHGRPPPQHFYNSEHMVSQET-SGFPSQR 413 A S + + S + S +SE +E + PS Sbjct: 1019 LYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSA- 1077 Query: 414 QNNPIMPQYPFPLPVFDMHNFPLRPPPPP-----PPPPVNMGWATPNMAAHPLLNLPYSL 468 +P + P P P P+ P P P P+ A+P A P P S Sbjct: 1078 --SPPPREVPVPTPA------PVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSA 1129 Query: 469 PPPPPPPPLPPP 480 P PP PP PP Sbjct: 1130 PLRPPEPPAGPP 1141 Score = 35.4 bits (80), Expect = 0.12 Identities = 22/62 (35%), Positives = 27/62 (43%) Query: 89 SPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCIS 148 S C S G + +S +S S S S S + S SSSSSS SSS + Sbjct: 1014 SSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAA 1073 Query: 149 LP 150 LP Sbjct: 1074 LP 1075 Score = 33.5 bits (75), Expect = 0.46 Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 4/85 (4%) Query: 17 NGTDFGVGEGPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQP--VLNAV 74 +G D + + SP AP P QPP P + P G P QP +L Sbjct: 579 SGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASL-PLGYPPHQPAYLLPPR 637 Query: 75 AAGTPAPQ-PQPPAESPACGDCVTS 98 G P P+ P PP P D V S Sbjct: 638 PDGPPPPEYPPPPPPPPHIYDFVNS 662 Score = 33.5 bits (75), Expect = 0.46 Identities = 76/379 (20%), Positives = 124/379 (32%), Gaps = 92/379 (24%) Query: 26 GPAAPSPGSAPVPGTQPPLQSFEGSPDAGQTVEVKPAGEQPLQP--------VLNAVAAG 77 GP SP SAP+ +PP G P + +P+ PL P V + Sbjct: 1120 GPTEESPPSAPLRPPEPP----AGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEV 1175 Query: 78 TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137 PAP+P PPA P PG A +AP +E + + D + S S Sbjct: 1176 VPAPEP-PPATPPQ----AKFPGPAS-RKAPRGVERTIRNLPLDHASLVKSWPEEVSRGG 1229 Query: 138 SSSSSSSSCISLPPVLSDGDD-DLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDI 196 S + ++ G + DL + + P + L LP+VE+ D Sbjct: 1230 RSRAGGRGRLTEEEEAEPGTEVDLAVLADLALTPARRG----LPALPAVEDSEATETSDE 1285 Query: 197 ELKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKIFEIFGPVAHPFYVLRF 256 +P ++S I+ + ++ PP PV P + Sbjct: 1286 AERPRPLLSHILLEHNYALAVKPTPP---------------APALRPPEPVPAPAALFSS 1330 Query: 257 NSSDHIESKGIKIKETMYFAPSMKDFTQYIFTEKLKQDKGSDASWKNDQEPPPEALDFSD 316 + + +E+ + + E +EP P+ L Sbjct: 1331 PADEVLEAPEVVVAEA--------------------------------EEPKPQQLQQQR 1358 Query: 317 DEKEKEAKQRKKSQIQGRKKLKSEFNEPGEDFTEVHQNWNAHSSASEHAKGYRNREFTRG 376 +E E+E GE+ E + ++ SS+S +G R R Sbjct: 1359 EEGEEE----------------------GEEEGEEEEEESSDSSSSSDGEGALRRRSLRS 1396 Query: 377 FSRARYPRSCHGRPPPQHF 395 +R R P PPP+ + Sbjct: 1397 HARRRRPPPPPPPPPPRAY 1415 Score = 32.7 bits (73), Expect = 0.78 Identities = 20/73 (27%), Positives = 25/73 (34%), Gaps = 4/73 (5%) Query: 22 GVGEGPAAPSPGSAPVPGTQPPLQSFEG----SPDAGQTVEVKPAGEQPLQPVLNAVAAG 77 G G GP P P A P G SP A + P + + G Sbjct: 533 GSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGG 592 Query: 78 TPAPQPQPPAESP 90 +P P P PP + P Sbjct: 593 SPPPAPTPPQQPP 605 Score = 32.3 bits (72), Expect = 1.0 Identities = 23/98 (23%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Query: 77 GTP-APQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSD---SDSDSETDSDSSSSS 132 GTP + P + T+ + +P R+ +S + + S S S + T + ++ ++ Sbjct: 270 GTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTAIAA 329 Query: 133 SSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKNFP 170 ++++++SSS+SSS +S S Q + N+P Sbjct: 330 TTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYP 367 Score = 32.0 bits (71), Expect = 1.3 Identities = 19/52 (36%), Positives = 19/52 (36%), Gaps = 27/52 (51%) Query: 435 PLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPP-----PLPPPP 481 P P PPPPPP PPPPPPP PL PP Sbjct: 598 PTPPQQPPPPPP----------------------PPPPPPPYLASLPLGYPP 627 Score = 32.0 bits (71), Expect = 1.3 Identities = 41/204 (20%), Positives = 69/204 (33%), Gaps = 19/204 (9%) Query: 289 EKLKQDKGSDASWKNDQEPPP-----EALDFSDDEKE------KEAKQRKKSQIQGRKKL 337 E+ Q+ S+ ++D+E EA+D + E E +E+ K + Sbjct: 966 EEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDG 1025 Query: 338 KSEFNEPGEDFTEVHQNWNAHSSASEHAKGYRNREFTRGFSRARYPRSCHGRPPPQHFYN 397 +++ E + + ++ SS+S + + + P + PP Sbjct: 1026 ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVP 1085 Query: 398 SEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMA 457 E P + +P+ P LP + P RP P P + P Sbjct: 1086 VPTPAPVEVP-VPERVAGSPVTP-----LP--EQEASPARPAGPTEESPPSAPLRPPEPP 1137 Query: 458 AHPLLNLPYSLPPPPPPPPLPPPP 481 A P P P P PL PPP Sbjct: 1138 AGPPAPAPRPDERPSSPIPLLPPP 1161 Score = 31.6 bits (70), Expect = 1.7 Identities = 24/58 (41%), Positives = 32/58 (55%) Query: 110 SLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENK 167 S T+ S + + + + SSS+SSSS SSSSSSSSS S SD + E N+ Sbjct: 318 SASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNR 375 Score = 30.8 bits (68), Expect = 3.0 Identities = 10/10 (100%), Positives = 10/10 (100%) Query: 437 RPPPPPPPPP 446 RPPPPPPPPP Sbjct: 1402 RPPPPPPPPP 1411 Score = 30.8 bits (68), Expect = 3.0 Identities = 11/19 (57%), Positives = 13/19 (68%) Query: 472 PPPPPLPPPPSSGDSNSHF 490 PPPPP PPPP + + S F Sbjct: 1403 PPPPPPPPPPRAYEPRSEF 1421 Score = 29.3 bits (64), Expect = 8.6 Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 13/58 (22%) Query: 390 PPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPV 447 PPP + S + G+P P P Y P P D P PPPPPPPP + Sbjct: 612 PPPPPYLASLPL------GYP------PHQPAYLLP-PRPDGPPPPEYPPPPPPPPHI 656 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 50.4 bits (119), Expect = 4e-06 Identities = 29/82 (35%), Positives = 44/82 (53%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S D S +++ + + DS ++SDS SDS SDSS SS SS SS+SS SS Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255 Query: 147 ISLPPVLSDGDDDLQIEKENKN 168 SD +D+ + ++ N Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGN 1277 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 7/82 (8%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S D S ++ + + DS ++SDS S SDS SDSS SS SS+SS SS SS Sbjct: 648 SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS 707 Query: 147 ISLPPVLSDGDDDLQIEKENKN 168 SD D + N N Sbjct: 708 -------SDSDSSDSSDSSNSN 722 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/74 (41%), Positives = 44/74 (59%), Gaps = 2/74 (2%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSD--SDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S + D S +++ + + +S E+SDS SDSDS SDSS+S+SS S SS+SS S Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734 Query: 145 SCISLPPVLSDGDD 158 S S SD D Sbjct: 735 SDSSNSSDSSDSSD 748 Score = 46.6 bits (109), Expect = 5e-05 Identities = 25/59 (42%), Positives = 36/59 (61%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 ++S D S +++ + + DS +SDS SDS SDSS+SS SS+SS SS S+S Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973 Score = 46.6 bits (109), Expect = 5e-05 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS+SS SS SS Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187 Score = 46.6 bits (109), Expect = 5e-05 Identities = 26/58 (44%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 +ES D S +++ + + DS ++SDS + SDS SDSS SS SS SS SS SS Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1205 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/58 (43%), Positives = 36/58 (62%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 + S D S ++E + + D+ +SDS + SDS SDSS+SS SS+SS SS+SS Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966 Score = 46.2 bits (108), Expect = 7e-05 Identities = 27/82 (32%), Positives = 43/82 (52%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S + + +++ + + DS ++SDS + SDS SDSS+SS SS S+SS SS S Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980 Query: 147 ISLPPVLSDGDDDLQIEKENKN 168 S S D ++ N Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSN 1002 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/59 (42%), Positives = 37/59 (62%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 + S D S +++ + + DS ++SDS + SDS SDSS SS+SS SS+SS SS+ Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS SS SS+SS Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS+SS SS SS Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS+SS SS SS SS SS Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160 Score = 45.8 bits (107), Expect = 9e-05 Identities = 24/59 (40%), Positives = 37/59 (62%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 ++S D S +++ + + DS ++SDS + S+S SDSS S SS SS SS+S+SS Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724 Score = 45.8 bits (107), Expect = 9e-05 Identities = 24/51 (47%), Positives = 33/51 (64%) Query: 94 DCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 D S +++ + + DS ++SDS + SDS SDSS+SS SS SS SS SS Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777 Score = 45.8 bits (107), Expect = 9e-05 Identities = 25/59 (42%), Positives = 35/59 (59%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 ++S D S +++ + + DS +SDS + SDS SDSS SS SS SS SS SS+ Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056 Score = 45.8 bits (107), Expect = 9e-05 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS +SDS SDS SDSS SS SS SS+SS SS Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061 Score = 45.8 bits (107), Expect = 9e-05 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076 Score = 45.8 bits (107), Expect = 9e-05 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS+SS SS SS SS Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103 Score = 45.8 bits (107), Expect = 9e-05 Identities = 26/58 (44%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S ++E + + DS +SDS SDS SDSS SS SS SS SS+SS Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124 Score = 45.8 bits (107), Expect = 9e-05 Identities = 26/58 (44%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S ++ + + DS E+SDS SDS SDSS SS SS SS SS+SS Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181 Score = 45.8 bits (107), Expect = 9e-05 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1217 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS +SDS SDS SDSS SS SS SS SS+SS Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S ++ + + DS ++SDS + SDS SDSS+SS SS SS SS SS Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS +SDS + SDS SDSS SS SS SS SS SS Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS + SDS SDSS SS SS SS SS SS Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1223 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1226 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S ++ + + DS ++SDS SDS SDSS+SS SS SS SS SS Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/59 (42%), Positives = 35/59 (59%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 +ES D S +++ + + DS ++SDS SDS S+SS SS SS SS SS SS+ Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 + S D S +++ + + DS ++SDS + SDS SDSS SS SS+SS SS SS Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS+SS SS SS SS SS Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 5/94 (5%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSS-----SSSSSSSSSS 141 + S D S +++ + + DS +SDS SDS SDSS+S SS+SS SS S Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797 Query: 142 SSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKD 175 S+SS S SD D + N + + D Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831 Score = 44.7 bits (104), Expect = 2e-04 Identities = 26/63 (41%), Positives = 39/63 (61%), Gaps = 4/63 (6%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDS----DSDSDSETDSDSSSSSSSSSSSSSSS 142 ++S D S +++ + + DS ++SDS DSDS + +DS +SS SS SS SS+SS Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877 Query: 143 SSS 145 SS Sbjct: 878 DSS 880 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/59 (42%), Positives = 35/59 (59%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 + S D S +++ + + DS E+S+S SDS SDS SS SS+SS SS SS+S Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/72 (40%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S D S +++ + + DS ++SDS SDS + +DS +SS SS+SS SS SS SS Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDS-SDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041 Query: 147 ISLPPVLSDGDD 158 S SD D Sbjct: 1042 SSDSSDSSDSSD 1053 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S ++ + + DS ++SDS SDS SDSS SS SS SS+SS SS Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS +SDS SDS SDSS+SS SS SS SS SS Sbjct: 1097 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/72 (37%), Positives = 39/72 (54%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S + S +++ + + DS +SDS + SDS SDSS+SS SS SS SS S S Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713 Query: 147 ISLPPVLSDGDD 158 S S+ D Sbjct: 714 DSSDSSNSNSSD 725 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/58 (43%), Positives = 33/58 (56%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS +SDS SDS SDSS SS SS SS SS SS Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/58 (41%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS S+SS SS SS+SS SS SS Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/58 (43%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS E+SDS S+S SDSS SS SS SS SS SS Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/59 (40%), Positives = 35/59 (59%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 ++S D S +++ + + DS ++S+S SDS SDSS SS SS SS SS SS+ Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/58 (41%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS + SDS S+SS SS SS SS SS SS Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/58 (41%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + +S ++SDS SDS SDSS SS SS SS+SS SS Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/58 (43%), Positives = 33/58 (56%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS +SDS SDS SDSS SS SS SS SS SS Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/58 (43%), Positives = 33/58 (56%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S ++ + + DS ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/59 (40%), Positives = 35/59 (59%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 ++S D S +++ + + DS ++SDS SDS SDS+ SS SS SS SS SS+ Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/72 (37%), Positives = 39/72 (54%), Gaps = 8/72 (11%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 + S D S ++ + + DS ++SDSDS + S++ + S SS SS+SS SS SS S Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS- 847 Query: 147 ISLPPVLSDGDD 158 SDG D Sbjct: 848 -------SDGSD 852 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/58 (41%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + +S ++SDS + SDS SDSS SS SS SS SS SS Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S D S +++ + + DS ++SDS SDS + +DS SS SS SS SS+SS SS Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSNSSDSSDSSDSSDSSDSSNSSDSSD 1146 Query: 147 ISLPPVLSDGDD 158 S SD D Sbjct: 1147 SSESSDSSDSSD 1158 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/59 (40%), Positives = 34/59 (57%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 + S D S +++ + + DS ++S+S SDS SDSS SS SS SS SS SS+ Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S + S +++ + + DS ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1142 SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS SS SS S+ Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS SS S+ SS SS Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS SS S+ SS SS SS Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS SDSS S+ SS SS SS SS Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244 Score = 43.5 bits (101), Expect = 4e-04 Identities = 26/65 (40%), Positives = 35/65 (53%) Query: 94 DCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVL 153 D S +++ + + DS ++SDS SDS++DS S S SS S S S SS S S Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653 Query: 154 SDGDD 158 SD D Sbjct: 654 SDSSD 658 Score = 43.5 bits (101), Expect = 4e-04 Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 12/71 (16%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDS------------DSDSETDSDSSSSSSS 134 ++S D S ++ + + DS ++SDSDS DSDS SDSS SS+S Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740 Query: 135 SSSSSSSSSSS 145 S SS SS SS+ Sbjct: 741 SDSSDSSDSSN 751 Score = 43.5 bits (101), Expect = 4e-04 Identities = 22/47 (46%), Positives = 32/47 (68%) Query: 98 SPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 S ++ + + DS ++SDS + SDS SDS+ SS+SS SS SS+SS Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDS-DSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 + S D S +++ + + DS +SDS DS+S +DS +SS SS SS SS SS SS Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998 Query: 146 CISLPPVLSDGDD 158 S SD D Sbjct: 999 DSSNSSDSSDSSD 1011 Score = 43.5 bits (101), Expect = 4e-04 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Query: 94 DCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVL 153 D S +++ + + DS ++SDS SDS + +DS SS SS SS+SS SS+SS S Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDS-SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033 Query: 154 SDGDD 158 SD D Sbjct: 1034 SDSSD 1038 Score = 43.5 bits (101), Expect = 4e-04 Identities = 24/58 (41%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 + S D S +++ + + +S ++SDS SDS SDSS+SS SS+SS SS SS Sbjct: 980 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037 Score = 43.5 bits (101), Expect = 4e-04 Identities = 24/59 (40%), Positives = 35/59 (59%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 ++S D S +++ + + +S ++SDS SDS SDSS SS SS SS SS SS+ Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092 Score = 43.5 bits (101), Expect = 4e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++S+S SDS SDSS SS SS SS SS SS Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169 Score = 43.5 bits (101), Expect = 4e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS S+S SDSS SS SS SS SS SS Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202 Score = 43.1 bits (100), Expect = 6e-04 Identities = 26/79 (32%), Positives = 42/79 (53%) Query: 98 SPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGD 157 S ++ + + DS ++ SDS+S S++DS S SS SS S SS SS+S S S Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613 Query: 158 DDLQIEKENKNFPLKTKDE 176 D ++K+ K++ + Sbjct: 614 SDSSDSSDSKSDSSKSESD 632 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/59 (40%), Positives = 32/59 (54%) Query: 101 AAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDD 159 +++ + + DS ++SDS SDS SDS S SS S S SS S S S SD D+ Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSS-SSSSSSSSSSS 145 ++S D S +++ + + +S ++S+S SDS SDS SS+SS SS+SS SS SS Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836 Query: 146 CISLPPVLSDGDDDLQIEKENKNFPLKTKD 175 S SD D + N++ + D Sbjct: 837 NSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866 Score = 43.1 bits (100), Expect = 6e-04 Identities = 26/82 (31%), Positives = 42/82 (51%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S D S +++ + + +S ++SDS ++S SDSS SS+SS S SS SS+S Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912 Query: 147 ISLPPVLSDGDDDLQIEKENKN 168 S S + +N N Sbjct: 913 DSSDSSNSSDSSESSNSSDNSN 934 Score = 43.1 bits (100), Expect = 6e-04 Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S D S +++ + + DS +SDS SDS +DS +SS SS+SS SS+SS SS Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS-SDSSNSSDSSNSSDSSNSSDSSD 1035 Query: 147 ISLPPVLSDGDD 158 S SD D Sbjct: 1036 SSDSSDSSDSSD 1047 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S ++ + + +S ++SDS SDS SDSS SS SS+SS SS SS Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS S+SS SS SS SS SS SS Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 33/58 (56%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 + S D S +++ + + DS ++S+S SDS SDSS SS SS SS SS SS Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + +S ++SDS SDS SDSS SS SS SS+SS SS Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S + S ++ + + DS ++SDS SDS SDSS SS+SS SS SS SS Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + +S ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++S+S SDS SDSS SS SS SS SS SS Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 34/58 (58%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + +S ++SDS SDS SDSS SS SS SS SS SS Sbjct: 1157 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/58 (41%), Positives = 33/58 (56%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 + S D S +++ + + DS ++SDS SDS SDSS SS SS SS S+ SS Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235 Score = 42.7 bits (99), Expect = 8e-04 Identities = 24/50 (48%), Positives = 32/50 (64%) Query: 109 DSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDD 158 DS ++SDS + + S++DS +SS SS SS+SS SS SS S SD D Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760 Score = 42.7 bits (99), Expect = 8e-04 Identities = 24/73 (32%), Positives = 41/73 (56%) Query: 72 NAVAAGTPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSS 131 N+ ++ + + ++S D S ++ + + DS ++S+S SDS SDSS S Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779 Query: 132 SSSSSSSSSSSSS 144 S+SS S+ SS+SS Sbjct: 780 SNSSDSNDSSNSS 792 Score = 42.7 bits (99), Expect = 8e-04 Identities = 23/58 (39%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S +++ + + DS ++SDS SDS ++SS SS SS SS SS+SS Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 2/76 (2%) Query: 94 DCVTSPGAAEPARAPDSLETSDSDSDSDSET-DSDSSSSSSSSSSSSSSSSSSCISLPPV 152 D S +++ + + DS ++SDS+S SDS++ DSDSS SS S SS SS+SS S S Sbjct: 553 DSSDSSNSSDSSDSSDS-DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611 Query: 153 LSDGDDDLQIEKENKN 168 S D K + + Sbjct: 612 DSSDSSDSSDSKSDSS 627 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/48 (47%), Positives = 29/48 (60%) Query: 98 SPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 S + + + DS + SDS S+S SDSS SS SS SSSSS SS+ Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/58 (39%), Positives = 35/58 (60%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D +S ++ + + DS ++S+S SDS SDS SS SS SS+S+SS S Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/58 (41%), Positives = 33/58 (56%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 + S D S +++ + + DS ++S+S SDS SDSS SS SS SS SS SS Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/58 (41%), Positives = 33/58 (56%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S D S ++ + + DS ++SDS S+S SDSS SS SS SS SS SS Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/58 (41%), Positives = 33/58 (56%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 + S D S +++ + + DS ++SDS SDS S+SS SS SS SS SS SS Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/47 (48%), Positives = 31/47 (65%) Query: 98 SPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 S +++ + + DS +S+S SDS SDSSSSS SS+SS SS SS Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/44 (47%), Positives = 31/44 (70%) Query: 102 AEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 ++ + + DS ++ SDSDS + +DS SS+SS SS SS SS+SS Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/58 (39%), Positives = 36/58 (62%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 ++S + +S + + + +S ++SDS + SDS SDSS+SS SS SS SS+SS Sbjct: 708 SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/51 (41%), Positives = 34/51 (66%) Query: 94 DCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 D S +++ + + +S ++S+S + SD+ SDSS+SS SS SS SS+SS Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S + D +S + + DS ++S+S SDS SDSS SS SS S S SS S Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631 Query: 147 ISLPPVLSDGDDDLQIEKENKN 168 S SD D N + Sbjct: 632 DS-----SDSDSKSDSSDSNSS 648 Score = 40.4 bits (93), Expect = 0.004 Identities = 26/82 (31%), Positives = 39/82 (47%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S D S +++ + DS ++SDS S+S SDSS SS S+S S+ S S Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273 Query: 147 ISLPPVLSDGDDDLQIEKENKN 168 S + D D E + N Sbjct: 1274 KSGNGNNNGSDSDSDSEGSDSN 1295 Score = 40.0 bits (92), Expect = 0.005 Identities = 20/37 (54%), Positives = 27/37 (72%) Query: 109 DSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 DS ++S+S SDS SDSS SS+SS +S+SS SS+ Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940 Score = 39.7 bits (91), Expect = 0.006 Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 109 DSLETSDSDSDSDSETD-SDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENK 167 DS ++ SDSDS++D SDS+SS SS +S SS SS+S S S D ++ Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684 Query: 168 N 168 N Sbjct: 685 N 685 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/37 (56%), Positives = 25/37 (67%) Query: 109 DSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 DS +SDS S+S SDSS SS+SS SS SS SS+ Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763 Score = 39.3 bits (90), Expect = 0.008 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSC 146 ++S + S +++ + + DS ++SDS + SDS S+SS SS SS+SS +S+SS Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDS-DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938 Query: 147 ISLPPVLSDGDDDLQIEKENKNFPLKTKD 175 + D + N + + D Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967 Score = 38.9 bits (89), Expect = 0.011 Identities = 26/71 (36%), Positives = 31/71 (43%) Query: 88 ESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCI 147 +S + D S D + SDS +DSDSS SS+SS SS SS S S Sbjct: 514 DSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD 573 Query: 148 SLPPVLSDGDD 158 S SD D Sbjct: 574 SNSSSDSDSSD 584 Score = 38.9 bits (89), Expect = 0.011 Identities = 20/48 (41%), Positives = 29/48 (60%) Query: 97 TSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 +S ++ +++ SDS SDS SDSS +S SS SS+SS+SS Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666 Score = 38.5 bits (88), Expect = 0.014 Identities = 24/51 (47%), Positives = 32/51 (62%), Gaps = 1/51 (1%) Query: 109 DSLETSDSDSDSDSET-DSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDD 158 DS +++ SDS +S++ DS +SS+SS SS SS SS SS S SD D Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691 Score = 38.1 bits (87), Expect = 0.018 Identities = 22/57 (38%), Positives = 29/57 (50%) Query: 112 ETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENKN 168 ++ SDSDS ++S SS SS S SS S+SSS S SD D + N + Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSS 602 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDS-DSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 ++S D S +++ + + DS ++SDS DS SDS +SDS S S + +++ S S S Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288 Query: 146 CISLPPVLSDGDD 158 S DD Sbjct: 1289 SEGSDSNHSTSDD 1301 Score = 37.4 bits (85), Expect = 0.032 Identities = 23/58 (39%), Positives = 30/58 (51%) Query: 87 AESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSS 144 +ES D S + + + SDS + SDS S+SS SS SS SS+SS SS Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756 Score = 37.0 bits (84), Expect = 0.041 Identities = 19/46 (41%), Positives = 28/46 (60%) Query: 100 GAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSS 145 G ++ + + S ++ SDS S++DS S+SSS S SS S SS S Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 590 Score = 37.0 bits (84), Expect = 0.041 Identities = 21/50 (42%), Positives = 27/50 (54%) Query: 109 DSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDD 158 DS ++ SDS + S++ S S SS S+SSS S SS S SD D Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597 Score = 36.6 bits (83), Expect = 0.054 Identities = 22/49 (44%), Positives = 25/49 (51%) Query: 109 DSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGD 157 D ++ SDS SDSS+SS SS SS S SS S S SD D Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSD 586 Score = 33.1 bits (74), Expect = 0.59 Identities = 18/61 (29%), Positives = 32/61 (52%) Query: 108 PDSLETSDSDSDSDSETDSDSSSSSSSSSSSSSSSSSSCISLPPVLSDGDDDLQIEKENK 167 P+S + S+ + D++SE+D++SSS +S +S S + S D D D + N Sbjct: 465 PNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNS 524 Query: 168 N 168 + Sbjct: 525 D 525 Score = 29.3 bits (64), Expect = 8.6 Identities = 20/46 (43%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 115 DSDSDSDSETDSDSSSSSSS-SSSSSSSSSSSCISLPPVLSDGDDD 159 D+D + SDSS S SS SS+SS SS SS S D D Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD 581 >gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 [Homo sapiens] Length = 491 Score = 50.4 bits (119), Expect = 4e-06 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 28/106 (26%) Query: 390 PPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPPVNM 449 PPP+ VSQET +++ +N I +P+ D N R PPPP P P + Sbjct: 272 PPPRS-------VSQETFRISTRKHSNLIT------VPIQDDSNSGAREPPPPAPAPAHH 318 Query: 450 GWATPNMAAHPLLNLPYSL--------PPPPPPP----PLPPPPSS 483 P P+++ P+ + PPPPPPP P+P PP + Sbjct: 319 H---PEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQA 361 Score = 39.7 bits (91), Expect = 0.006 Identities = 34/117 (29%), Positives = 43/117 (36%), Gaps = 17/117 (14%) Query: 390 PPPQHF---YNSEHMVSQETSGFPSQRQNNPIMP-----QYPFPLP---VFDMHNFPLRP 438 P P H Y + +VS P Q+ P P +P P P H + Sbjct: 313 PAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQA 372 Query: 439 PPPP---PPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPPSSGDSNSHFGP 492 PPPP PPP+ P +N P PP PPPP PP + H+ P Sbjct: 373 PPPPMTSAPPPITPPPGHIIAQMPPYMNHP---PPGPPPPQHGGPPVTAPPPHHYNP 426 Score = 36.2 bits (82), Expect = 0.070 Identities = 39/149 (26%), Positives = 47/149 (31%), Gaps = 44/149 (29%) Query: 383 PRSCHGRPPPQHFYNSEHMVSQETSGFPSQRQNNPIMPQYPFPLPVFDMHNFP--LRPPP 440 P H P P + H+V + P PI P P + P + PP Sbjct: 349 PPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPP-----PGHIIAQMPPYMNHPP 403 Query: 441 PPPPPPVNMGWATPNMAAHPLLNLPYSLPP----------------------------PP 472 P PPPP + G P A P P SLP PP Sbjct: 404 PGPPPPQHGG--PPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPP 461 Query: 473 PPPPLPPPPSS-------GDSNSHFGPYY 494 PPP L PPS + + PYY Sbjct: 462 PPPRLQGPPSQTPLPGPHHPDQTRYRPYY 490 >gi|4557329 fas ligand [Homo sapiens] Length = 281 Score = 50.1 bits (118), Expect = 5e-06 Identities = 23/45 (51%), Positives = 23/45 (51%), Gaps = 21/45 (46%) Query: 437 RPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPPP 481 RPPPPPPPPP LPPPPPPPPLPP P Sbjct: 44 RPPPPPPPPP---------------------LPPPPPPPPLPPLP 67 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/61 (37%), Positives = 26/61 (42%), Gaps = 4/61 (6%) Query: 421 QYPFPLPVFDMHNFPLRPPPPPPPPPVNMGWATPNMAAHPLLNLPYSLPPPPPPPPLPPP 480 Q PF P ++ P PP G P + P PPPPPPPPLPPP Sbjct: 2 QQPFNYPYPQIYWVDSSASSPWAPP----GTVLPCPTSVPRRPGQRRPPPPPPPPPLPPP 57 Query: 481 P 481 P Sbjct: 58 P 58 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 12/37 (32%) Query: 410 PSQRQNNPIMPQYPFPLPVFDMHNFPLRPPPPPPPPP 446 P QR+ P P P PLP PPPPPPP P Sbjct: 40 PGQRRPPP--PPPPPPLP----------PPPPPPPLP 64 >gi|33239445 eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa [Homo sapiens] Length = 814 Score = 50.1 bits (118), Expect = 5e-06 Identities = 51/235 (21%), Positives = 88/235 (37%), Gaps = 40/235 (17%) Query: 27 PAAPSPGSAPVPGTQPPLQSFEGSPDAGQT---------VEVKPAGEQPLQPVLNAVAAG 77 P P + P P + G+P+A T E P E +P A AA Sbjct: 19 PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78 Query: 78 TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137 P+ P PPA G P A+ AP + D SDS ++ S+ + + ++ Sbjct: 79 GPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGE-QARDERSDSRAQAVSEDAGGNEGRAA 136 Query: 138 SSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIE 197 + P L +GD D + ++F +E LL ++ Sbjct: 137 EAE---------PRALENGDADEPSFSDPEDFVDDVSEEELLGDV--------------- 172 Query: 198 LKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKIFEIFGPVAHPFY 252 LK + I+ +++++++ + P E + + KIF FG + + FY Sbjct: 173 LKDRPQEADGIDSVIVVDNVPQVGPDRLEKL-----KNVIHKIFSKFGKITNDFY 222 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.130 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,460,692 Number of Sequences: 37866 Number of extensions: 2067975 Number of successful extensions: 55090 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 845 Number of HSP's successfully gapped in prelim test: 1293 Number of HSP's that attempted gapping in prelim test: 21102 Number of HSP's gapped (non-prelim): 17960 length of query: 494 length of database: 18,247,518 effective HSP length: 106 effective length of query: 388 effective length of database: 14,233,722 effective search space: 5522684136 effective search space used: 5522684136 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.