Guide to the Human Genome
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Search of human proteins with 192807334

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|192807334 arsenate resistance protein 2 isoform d [Homo
sapiens]
         (872 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]  1809   0.0  
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]  1802   0.0  
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]   1801   0.0  
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]  1795   0.0  
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               79   2e-14
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    70   1e-11
gi|210032580 SET domain containing 1B [Homo sapiens]                   67   6e-11
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    66   2e-10
gi|83921609 hypothetical protein LOC127254 [Homo sapiens]              65   3e-10
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    64   5e-10
gi|55741677 SET domain containing 1A [Homo sapiens]                    64   8e-10
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ...    63   1e-09
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    62   2e-09
gi|221219020 NYD-SP11 protein [Homo sapiens]                           62   3e-09
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform...    62   3e-09
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    60   7e-09
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            60   9e-09
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                59   1e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     59   3e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            58   3e-08
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    58   3e-08
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    58   3e-08
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              58   3e-08
gi|4557509 cylicin 2 [Homo sapiens]                                    57   6e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          57   7e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              57   7e-08
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    57   7e-08
gi|55956788 nucleolin [Homo sapiens]                                   57   1e-07
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    57   1e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    56   1e-07

>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
          Length = 872

 Score = 1809 bits (4685), Expect = 0.0
 Identities = 872/872 (100%), Positives = 872/872 (100%)

Query: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
           MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR
Sbjct: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60

Query: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
           NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV
Sbjct: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120

Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
           HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180

Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
           RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI
Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240

Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
           DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER
Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300

Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
           KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360

Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
           SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420

Query: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
           CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW
Sbjct: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480

Query: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
           NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS
Sbjct: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540

Query: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
           EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE
Sbjct: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600

Query: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
           RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL
Sbjct: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660

Query: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
           EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK
Sbjct: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720

Query: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSLTPG 780
           KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSLTPG
Sbjct: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSLTPG 780

Query: 781 LPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGG 840
           LPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGG
Sbjct: 781 LPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGG 840

Query: 841 YPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 872
           YPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
Sbjct: 841 YPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 872


>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
          Length = 871

 Score = 1802 bits (4668), Expect = 0.0
 Identities = 871/872 (99%), Positives = 871/872 (99%), Gaps = 1/872 (0%)

Query: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
           MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR
Sbjct: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60

Query: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
           NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV
Sbjct: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120

Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
           HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180

Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
           RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI
Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240

Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
           DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER
Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300

Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
           KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360

Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
           SFDEGSVSESESESESGQAEEEKEEAE ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAE-ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 419

Query: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
           CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW
Sbjct: 420 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 479

Query: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
           NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS
Sbjct: 480 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 539

Query: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
           EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE
Sbjct: 540 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 599

Query: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
           RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL
Sbjct: 600 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 659

Query: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
           EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK
Sbjct: 660 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 719

Query: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSLTPG 780
           KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSLTPG
Sbjct: 720 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSLTPG 779

Query: 781 LPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGG 840
           LPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGG
Sbjct: 780 LPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGG 839

Query: 841 YPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 872
           YPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
Sbjct: 840 YPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 871


>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
          Length = 876

 Score = 1801 bits (4666), Expect = 0.0
 Identities = 871/876 (99%), Positives = 871/876 (99%), Gaps = 4/876 (0%)

Query: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
           MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR
Sbjct: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60

Query: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
           NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV
Sbjct: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120

Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
           HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180

Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
           RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI
Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240

Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
           DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER
Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300

Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
           KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360

Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
           SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420

Query: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
           CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW
Sbjct: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480

Query: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
           NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS
Sbjct: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540

Query: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
           EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE
Sbjct: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600

Query: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
           RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL
Sbjct: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660

Query: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
           EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK
Sbjct: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720

Query: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ----S 776
           KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ     
Sbjct: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 780

Query: 777 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 836
           LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR
Sbjct: 781 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 840

Query: 837 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 872
           GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
Sbjct: 841 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 876


>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
          Length = 875

 Score = 1795 bits (4649), Expect = 0.0
 Identities = 870/876 (99%), Positives = 870/876 (99%), Gaps = 5/876 (0%)

Query: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
           MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR
Sbjct: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60

Query: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
           NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV
Sbjct: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120

Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
           HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180

Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
           RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI
Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240

Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
           DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER
Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300

Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
           KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360

Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
           SFDEGSVSESESESESGQAEEEKEEAE ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAE-ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 419

Query: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
           CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW
Sbjct: 420 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 479

Query: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
           NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS
Sbjct: 480 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 539

Query: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
           EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE
Sbjct: 540 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 599

Query: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
           RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL
Sbjct: 600 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 659

Query: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
           EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK
Sbjct: 660 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 719

Query: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ----S 776
           KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ     
Sbjct: 720 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 779

Query: 777 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 836
           LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR
Sbjct: 780 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 839

Query: 837 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 872
           GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
Sbjct: 840 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 875


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 50/142 (35%), Positives = 79/142 (55%), Gaps = 9/142 (6%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE---KKEDGKQAENDSSN-DDK 324
           ++E+EE+Q  + GE  K+++   G   G  ++  N+K E   +KEDGK+ E+   N +D 
Sbjct: 130 QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDG 189

Query: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384
            +K E + ++E++KE  + +  +  K++  K  G D      V E E E E G+ E+E  
Sbjct: 190 KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV----KVKEDEKEREDGK-EDEGG 244

Query: 385 EAEEALKEKEKPKEEEWEKPKD 406
             EEA KEKE  KEEE  K +D
Sbjct: 245 NEEEAGKEKEDLKEEEEGKEED 266



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 18/162 (11%)

Query: 252 AAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-GAGLGDGERKTNDKDEKK- 309
           AA +K E   + +    ++E++ E+ G+ G+  K E+G   G    +G  K  D  EK+ 
Sbjct: 120 AAEVKNEEEDQKE----DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175

Query: 310 -----------EDGKQA-ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS 357
                      EDGK+  E++   +D+ +  +G  +++ K++  +KE K    K + K  
Sbjct: 176 GKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKER 235

Query: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE 399
            D   DEG   E   + +    EEE+ + E+ +KE +  KEE
Sbjct: 236 EDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 44/175 (25%), Positives = 74/175 (42%), Gaps = 9/175 (5%)

Query: 243 ADAIVKMLDAAVIKM---EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE 299
           A A+ +    AV++    E     + +I E    E++  +      KEE    A    GE
Sbjct: 60  AQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEV-----KEENIEDATEKGGE 114

Query: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKK-RNRKHSG 358
           +K     E K + +  + D  + ++ K   G  DK+EK E+  KE K  ++K  + K   
Sbjct: 115 KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174

Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECK 413
           D    E      E   E G+ E+E+E+ +E    KE    +E    K+   ++ K
Sbjct: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVK 229



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 7/98 (7%)

Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEK-KEDGKQAE 316
           +G  E+     E E+EEE   + G+  + E+G+      +G+     +DEK +EDGK+ E
Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242

Query: 317 NDSSND------DKTKKSEGDGDKEEKKEDSEKEAKKS 348
             +  +      D  ++ EG  + E K++D +KE  +S
Sbjct: 243 GGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 3/64 (4%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
           K EG    D+++ E E+E E   +    +++E G+    L + E    + + K++DGK+ 
Sbjct: 220 KKEG---KDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKE 276

Query: 316 ENDS 319
           E  S
Sbjct: 277 EPQS 280


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 10/155 (6%)

Query: 258  EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE------- 310
            EG  E +    E E EEE+    GE   + EG    G G+GE +   + E++E       
Sbjct: 864  EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923

Query: 311  DGKQAENDSSNDD---KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSV 367
            +G++ E +   ++   + +  EG+G++EE + + E+E  +   +   +  G++   EG  
Sbjct: 924  EGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE 983

Query: 368  SESESESESGQAEEEKEEAEEALKEKEKPKEEEWE 402
             E E E E  + EEE EE  E  +E E   EEE E
Sbjct: 984  EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 45/156 (28%), Positives = 79/156 (50%), Gaps = 14/156 (8%)

Query: 258  EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK---- 313
            EG  E +     + EEEE  GK  E  ++ EG      G+GE +  + + ++E+G+    
Sbjct: 899  EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE 958

Query: 314  ----QAENDSSNDDKTKKSEGDGDKEE-----KKEDSEKEAKKSSKKRNRKHSGDDSFDE 364
                + E +   + + ++ EG+G++EE     ++E+ E+E ++  +         +  +E
Sbjct: 959  EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018

Query: 365  GSVSESESESESGQAEEEKEEAEEALKEKEKPKEEE 400
            G V E E E E G+ E E+EE EE  +E+EK  E E
Sbjct: 1019 GEV-EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGE 1053



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 84/164 (51%), Gaps = 8/164 (4%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGE-PSKKEEGRA----GAGLGDGERKTNDKDEKKE 310
           ++EGG   + +   +EEEEE  G+  E   ++EEG      G G G+ E +  + +E+ E
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872

Query: 311 DGK-QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS- 368
           +G+ + E +    +  ++ EG+G++EE + + E+E +   ++   +  G++  +EG    
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932

Query: 369 -ESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLE 411
            E E E E    E E EE E   + +E+  E E E+  +  G E
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 40/137 (29%), Positives = 72/137 (52%), Gaps = 5/137 (3%)

Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE 329
           +EEE E   + GE   +EEG  G G  +GE    + +E++ +G + E +   + + ++ E
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG-EGEEEGEGEGEEEEGE 901

Query: 330 GDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS----ESESESESGQAEEEKEE 385
           G+G++E + E  E+E +   ++   +  G+   +EG       E E E E G+ E E+EE
Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961

Query: 386 AEEALKEKEKPKEEEWE 402
            E   +E+ + + EE E
Sbjct: 962 GEGEGEEEGEGEGEEGE 978



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 10/145 (6%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
           K EGG        E E  E + GK     ++EEG      G+GE +  + +E++ +GK  
Sbjct: 808 KEEGG--------EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE 859

Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
           E     + + +  EG+G+ EE  E+ E E ++  +    +  G+   +E    E E E  
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEE--EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917

Query: 376 SGQAEEEKEEAEEALKEKEKPKEEE 400
            G+ EEE EE E   +E+E   E E
Sbjct: 918 EGKGEEEGEEGEGEGEEEEGEGEGE 942



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 51/174 (29%), Positives = 82/174 (47%), Gaps = 15/174 (8%)

Query: 255 IKMEGGTENDLRILEQE---EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE-KKE 310
           +K+ GG +    IL  +   + E   GK     + E+G  G G G  E  ++  +  + E
Sbjct: 613 VKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDE 672

Query: 311 DGKQAENDSSNDDKTKKSEGD---GDKEE-KKEDSEKEAKKS-----SKKRNRK--HSGD 359
           + ++ E D    +  +  EG+    +KEE KK D E++ +K       K+RN++    G+
Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE 732

Query: 360 DSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECK 413
           +   EG   E + E E  +  E KEE E    E E+ KEE   K ++ AG E K
Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 39/163 (23%), Positives = 83/163 (50%), Gaps = 10/163 (6%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA---GAGLGDGERKTNDKDEKKEDG 312
           +ME   E +  + E+EE +++ G+  E  ++E+G        + +G  + + + E++E  
Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD 744

Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372
           ++ E +   + K    EG+G++ E + + E+  +K  ++  ++  G++  D+G   E E+
Sbjct: 745 REEEEEKEGEGK---EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEET 801

Query: 373 ESESGQAEEEKE----EAEEALKEKEKPKEEEWEKPKDAAGLE 411
           E    + EE  E    E EE   E+E+ +EE   + ++  G E
Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE 844



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 2/149 (1%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
           +ME G E +    E+EE + +  +  E   KEEG      G+ E++  ++ +++  GK+ 
Sbjct: 726 EMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785

Query: 316 ENDSSNDD-KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES 374
           + +   D  + ++ E +G  EEK+E  E E  +  + +  +   ++   EG   E E E 
Sbjct: 786 KGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE-GEGEEEEGEGEE 844

Query: 375 ESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
           E G+ EEE+ E +   + +E   EEE E+
Sbjct: 845 EEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 42/148 (28%), Positives = 76/148 (51%), Gaps = 7/148 (4%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE---DGKQAENDSSNDDKT 325
           EQE++E + G   E +++ E       G+GE +  D++E++E   +GK+       + + 
Sbjct: 709 EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER 768

Query: 326 KKSEGDGDKEE---KKEDSEKEAKKSS-KKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
           +K EG+  KEE   K+E  E+E  +   ++   +  G++  + G V   E E   G+ EE
Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828

Query: 382 EKEEAEEALKEKEKPKEEEWEKPKDAAG 409
           E+EE E   +E E  +EE   + ++  G
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEG 856



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 47/158 (29%), Positives = 80/158 (50%), Gaps = 28/158 (17%)

Query: 269  EQEEEE-----EQAGKPGEPSKKEE---GRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320
            E EEEE     E+ G+ GE   +EE   G    G G+GE +  + + ++E+G + E +  
Sbjct: 911  EGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG-EGEGEEE 969

Query: 321  NDDKTKKSEGDGDKEE-----KKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
             + + ++ EG+G++EE     ++E+ E+E ++  +         +  +EG V E E E E
Sbjct: 970  GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV-EGEVEGE 1028

Query: 376  SGQAEEEKEEAEEALKEKEK-------------PKEEE 400
             G+ E E+EE EE  +E+EK              +EEE
Sbjct: 1029 EGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066



 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 40/144 (27%), Positives = 70/144 (48%), Gaps = 10/144 (6%)

Query: 270  QEEEEEQAGKPGEPSKKEEGRAGAGLGDGER------KTNDKDEKKEDGKQAENDSSNDD 323
            +EE EE  G+  E   + EG  G G G+ E       +   + E +E+G+    +   + 
Sbjct: 922  EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEG 981

Query: 324  KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS----ESESESESGQA 379
            + ++ EG+G++EE +E+ E+E +   +        ++   EG V     E E E E G+ 
Sbjct: 982  EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041

Query: 380  EEEKEEAEEALKEKEKPKEEEWEK 403
            E E+ E E   +E  + +EEE E+
Sbjct: 1042 EGEEREKEGEGEENRRNREEEEEE 1065



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 40/143 (27%), Positives = 74/143 (51%), Gaps = 3/143 (2%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERK-TNDKDEKKEDGKQAENDSSNDDKTKK 327
           E+E+EE +  K     K+E+G      G+GE + T  + E+KE+G + E     + K ++
Sbjct: 767 EREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER 826

Query: 328 SEGDGDKEEKKEDSEKEAKKSS-KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386
            E + + E ++E+ E E ++   ++   +  G++  +EG   E E E   G+ EEE+ E 
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE-GEEEGEEGEGEGEEEEGEG 885

Query: 387 EEALKEKEKPKEEEWEKPKDAAG 409
           E   + + + +EEE E   +  G
Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEG 908



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 41/152 (26%), Positives = 75/152 (49%), Gaps = 11/152 (7%)

Query: 269  EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
            E+E E E   + GE   +EEG  G G G+ E    + ++ + +G++ E +   +++  + 
Sbjct: 905  EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE--EG 962

Query: 329  EGDGDKEEKKEDSEKEA---KKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
            EG+G++E + E  E E    ++  +    +  G++  +E    E E E E  + EE + E
Sbjct: 963  EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022

Query: 386  AE------EALKEKEKPKEEEWEKPKDAAGLE 411
             E      E   E+E+ +EE  E+ K+  G E
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEE 1054



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 21/173 (12%)

Query: 258  EGGTENDLRILEQEEEEEQAGKPGEPSK-KEEGRAGAGLGD-----GERKTNDKDEKKED 311
            EG  E +    E+EE E +  + GE  + +EEG  G G G+     GE +   + E +E+
Sbjct: 839  EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898

Query: 312  GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKK------------SSKKRNRKHSGD 359
              + E +   + + ++ EG+G  EE+ E+ E E ++              ++   +  G+
Sbjct: 899  EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE 958

Query: 360  DSFDEG---SVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAG 409
            +   EG      E E E   G+ EEE+ E E   +E E+  EEE E  ++  G
Sbjct: 959  EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 37/129 (28%), Positives = 70/129 (54%), Gaps = 12/129 (9%)

Query: 269  EQEEEEEQAGKPGEPSKKEEGRAGAGLGD-GERKTNDKDEKKEDGK-----QAENDSSND 322
            E EEE E  G+ GE   +EE   G G  + GE +  ++ E +E+G+     + E +   +
Sbjct: 965  EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024

Query: 323  DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382
             + ++ EG+G++EE +E+ E+  K+   + NR++  ++  +EG         E+G+ E E
Sbjct: 1025 VEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY------QETGEEENE 1078

Query: 383  KEEAEEALK 391
            +++ EE  K
Sbjct: 1079 RQDGEEYKK 1087



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 54/247 (21%), Positives = 108/247 (43%), Gaps = 5/247 (2%)

Query: 165 ETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVF 224
           E E  ++    K D   Q+ ++    H+ E     +   +E     +E  G  +      
Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752

Query: 225 LSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPS 284
               E G  + +  + +K +   K  + A  + +G  E D    E+EE E +  +  E  
Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812

Query: 285 KKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKE 344
           + E G    G G+ E +  + + ++E+G+  E +   +++  + EG G++E ++ + E+E
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE--EGEGKGEEEGEEGEGEEE 870

Query: 345 AKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKP 404
            ++   +   +    +  +EG   E E E E G+ E E+E   E  +E+ + K EE  + 
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEG---EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927

Query: 405 KDAAGLE 411
            +  G E
Sbjct: 928 GEGEGEE 934



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 43/158 (27%), Positives = 76/158 (48%), Gaps = 15/158 (9%)

Query: 258  EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
            EG  E +    E EEEE +    GE  ++ EG    G G+GE +  + + ++E+G++   
Sbjct: 945  EGEGEEEEGEWEGEEEEGE----GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000

Query: 318  DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
            +    ++    EG+G+ EE+ E+ E E +   ++   +   ++  +EG   E E E E  
Sbjct: 1001 EEGEGEE----EGEGEGEEE-EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055

Query: 378  QAEEEKEEAEEAL------KEKEKPKEEEWEKPKDAAG 409
            +   E+EE EE        +E E+   EE++K     G
Sbjct: 1056 RRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKG 1093



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 49/190 (25%), Positives = 85/190 (44%), Gaps = 27/190 (14%)

Query: 242 KADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGL-GDGER 300
           KA ++ +  D    + +G  E      E  ++EE+     E  +K++GR      G+GE+
Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEER-----EKGEKDKGRGEMERPGEGEK 694

Query: 301 KTNDKDE-KKEDGKQAENDSSNDDKTKK---------SEGDGDKEEKKEDSEKEAKKSSK 350
           +  +K+E KK DG++ E         K+          E  G+ EE++ D E+E +K  +
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754

Query: 351 KR-----------NRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE 399
            +             K  G+   +E +  E + E E  Q E E+EE E   +EKE+  E 
Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814

Query: 400 EWEKPKDAAG 409
           E  + ++  G
Sbjct: 815 EGGEVEEGKG 824



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 33/136 (24%), Positives = 69/136 (50%), Gaps = 9/136 (6%)

Query: 269  EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK-- 326
            E EEEEE     GE   + EG  G G G+ E    + +E++++G+  EN  + +++ +  
Sbjct: 1012 EGEEEEE-----GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066

Query: 327  -KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
             K +  G++E +++D E+  K S  K + K+    ++ + SV+ ++   +  Q  +   +
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKE-QRSKMPVQ 1125

Query: 386  AEEALKEKEKPKEEEW 401
            ++  LK      ++ W
Sbjct: 1126 SKRLLKNGPSGSKKFW 1141



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 16/139 (11%)

Query: 283 PSKKE--EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKED 340
           P +KE  E   G G+ + E + N+++ K   G++ + +  +DD T K+E      E K  
Sbjct: 587 PEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAE----VSEGKAK 642

Query: 341 SEKEAKKSSKKRNRKHSGDDSFDEGSVSES---ESESESGQAEEEKEEAEEALK-EKEKP 396
           S  EA+   + R     GD + +EGS       + E E G+ ++ + E E   + EKE  
Sbjct: 643 SVGEAEDGPEGR-----GDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA 697

Query: 397 KEEEWEKPKDAAGLECKPR 415
           ++EEW+K +D    E K R
Sbjct: 698 EKEEWKK-RDGEEQEQKER 715



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 15/163 (9%)

Query: 259 GGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-----GAGLGDGERKTNDKDEKKEDGK 313
           G    D  + E ++ +E      E S+ +EG+A       G+   +  T  +    E+ +
Sbjct: 530 GELTQDTALTENDDSDEYE----EMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVE 585

Query: 314 QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAK-KSSKKRNRKHSGDDSFDEGSVSESES 372
             E     +D    S+G+G +E++ E +E+  K    +K   +   DD  D+  VSE ++
Sbjct: 586 IPEEKEGAED----SKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKA 641

Query: 373 ESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
           +S  G+AE+  E   +   E+     E W+  +   G + K R
Sbjct: 642 KS-VGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGR 683


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 14/155 (9%)

Query: 259  GGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEND 318
            GG E++   L +E+E  +  +  E  ++EE        D +  ++D+DE + D    + D
Sbjct: 1032 GGEEDEKESLSEEQESTEEEEEAEEEEEEED-------DDDDDSDDRDESEND----DED 1080

Query: 319  SSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
            ++  + ++K EGD D+EE       +A+ +S   + + S  +S  E S S SE E E   
Sbjct: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVA 1140

Query: 379  AEEEKEEAEEALKEKEKPKE---EEWEKPKDAAGL 410
             EEE+EE EE +  +E       E++E+  + A L
Sbjct: 1141 REEEEEEEEEEMVAEESMASAGPEDFEQDGEEAAL 1175



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 27/170 (15%)

Query: 269  EQEEEEEQAGKPGEPSKKEEGRAGAGLG-------DGERKTNDKDEKKEDGKQAENDSSN 321
            E+E + + A  P E +K++    G           D   + ++K+   E+ +  E +   
Sbjct: 995  ERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEA 1054

Query: 322  DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSV-------------- 367
            +++ ++ + D D  + +++SE + + ++     +    DS +E +V              
Sbjct: 1055 EEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSE 1114

Query: 368  ----SESESESESGQAEEEKEEAEEALKEKEKPKEEEW--EKPKDAAGLE 411
                SE ES SES  +  E EE   A +E+E+ +EEE   E+   +AG E
Sbjct: 1115 SSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPE 1164



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 36/125 (28%), Positives = 57/125 (45%), Gaps = 14/125 (11%)

Query: 289  GRAGAGLGDGERKT----NDKDEKKE--------DGKQAENDSSNDDKTKKSEGDGDKEE 336
            G  G GLG G R      + K ++KE        D K+    +S D++ ++SE + D++ 
Sbjct: 943  GYEGLGLGIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDM 1002

Query: 337  KKEDSE--KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE 394
                 E  K   K    R R     +    G   E ES SE  ++ EE+EEAEE  +E++
Sbjct: 1003 ADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEED 1062

Query: 395  KPKEE 399
               ++
Sbjct: 1063 DDDDD 1067



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 21/62 (33%), Positives = 24/62 (38%)

Query: 760 PALPEIKPAQPPGPAQSLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPP 819
           P LP   P  PP P   + P LP P   P    P     PP L    G   P +    PP
Sbjct: 688 PPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPP 747

Query: 820 YP 821
           +P
Sbjct: 748 FP 749



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 22/65 (33%), Positives = 22/65 (33%), Gaps = 12/65 (18%)

Query: 760 PALPEIKPAQPPGPAQSLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPP 819
           P  P   P  PP P     PG P P   P    P   P PP          PAV    PP
Sbjct: 682 PPPPGFPPLPPPPPPPPPQPGFPMPPPLP----PPPPPPPP--------AHPAVTVPPPP 729

Query: 820 YPHAP 824
            P  P
Sbjct: 730 LPAPP 734


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 10/152 (6%)

Query: 259 GGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAG-----LGDGERKTNDKDEKKEDGK 313
           GG E+   + E E   E  G+ GE + + E    +G      G+GE +T  K E+ ED  
Sbjct: 742 GGQED---VAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDEN 798

Query: 314 QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSF--DEGSVSESE 371
           +AE    N+ + +      D E K  + E E+++ S + + +   D+    D G     +
Sbjct: 799 EAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGD 858

Query: 372 SESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
           SE E  + EE++EE EE  +E+E+ +EEE E+
Sbjct: 859 SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEE 890



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 48/210 (22%), Positives = 82/210 (39%), Gaps = 63/210 (30%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGR--------------AGAGLGD--GERKTNDKDEKKEDG 312
           E+EEE    G   +P  K E +                A + D  G++K N   +  ED 
Sbjct: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQ--EDV 747

Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKK------------------EDSEKEAKKSSKKRNR 354
            +AE+      +  ++ G+G+ EEK                   E+ E E +   K  N 
Sbjct: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807

Query: 355 -KHSGDDSFDEGSVSESESESES--------------------------GQAEEEKEEAE 387
            +  G+   ++G +  +E E+ES                          G +EEE+EE E
Sbjct: 808 GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEE 867

Query: 388 EALKEKEKPKEEEWEKPKDAAGLECKPRPL 417
           E  +E+E+ ++EE E+ ++    +    PL
Sbjct: 868 EQEEEEEEEEQEEEEEEEEEEEEKGNEEPL 897


>gi|83921609 hypothetical protein LOC127254 [Homo sapiens]
          Length = 1530

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 48/180 (26%), Positives = 85/180 (47%), Gaps = 17/180 (9%)

Query: 257 MEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGL-GDGERKTNDKDEKKEDGKQA 315
           +E   EN L+   +E+ E    K GE S  EEG+A   + G  +   +DK +  +  K++
Sbjct: 486 LEDDQENTLKYEYEEDFEVDEEKQGEKSN-EEGQADVQMNGIPQSPLDDKKDNLDPEKES 544

Query: 316 ENDSSNDDKTK---KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS-GDDSFDEGSVSESE 371
           E  S      +   K E DG  E + E+ +++ K +S   +R H    DS DE +V + E
Sbjct: 545 ETSSQKAPDARDNVKDENDGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDRE 604

Query: 372 SESESGQAEEEKEEAEEALKEKEKPKE-----------EEWEKPKDAAGLECKPRPLHKT 420
           + ++S   E  +  + + L E +KP++           E  ++    A +E KP P+ ++
Sbjct: 605 AHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKADVETKPMPIDES 664



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 51/210 (24%), Positives = 78/210 (37%), Gaps = 44/210 (20%)

Query: 247  VKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEP--------SKKEEGRAGAGLGDG 298
            V  L  A    EG  E  + + +  E EE+A    E         SK+E+G   A LG G
Sbjct: 919  VAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILG-G 977

Query: 299  ERKTNDKDE--------------------KKEDGKQAENDSSNDDKTKKSEGDGDK---- 334
            E    ++ E                    +  +G   E   + +    K + +G++    
Sbjct: 978  EEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAFLCKEDVEGEEMVTE 1037

Query: 335  -EEKKEDSEKE--------AKKSSKKRNRKHS--GDDSFDEGSVSESESESESGQAEEEK 383
             E  +ED  KE        A++  K    K S    DS  E     +  + E    EE+K
Sbjct: 1038 AEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQK 1097

Query: 384  EEAEEALKEKEKPKEEEWEKPKDAAGLECK 413
             +AEE   E E   EEE + P +  G + +
Sbjct: 1098 LKAEEGETETEVRAEEETKAPPNEMGSDAE 1127



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 31/147 (21%), Positives = 65/147 (44%), Gaps = 3/147 (2%)

Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
           +G +E++L   +Q+ +   +          +    + +GD E  T D    +   + +  
Sbjct: 563 DGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHT-DSSTDESARRSSSQ 621

Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES-ES 376
           + S +DK +KS    ++  + E  ++E  K+  +  +    D+SF+      +E  + E 
Sbjct: 622 ELSENDKPRKSHLPIEESLEIEIEDQEITKADVE-TKPMPIDESFENVLKEGTEKGTQEI 680

Query: 377 GQAEEEKEEAEEALKEKEKPKEEEWEK 403
            +   EK     + +EKEK K + WE+
Sbjct: 681 AEGLSEKSGKHVSAEEKEKDKSKLWEE 707



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 26/110 (23%), Positives = 49/110 (44%), Gaps = 9/110 (8%)

Query: 304  DKDEKKEDGKQA--ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK--HSGD 359
            D+D ++E+ K+   E ++  D   + SEGDGD E +    + E     +    +  H G 
Sbjct: 1291 DEDPEEEEDKECTLETEAMQD---RNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGG 1347

Query: 360  DSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAG 409
            ++ +  + +E        +  EEK  A +A    +  +EE W +  +  G
Sbjct: 1348 ETAE--TAAEEREVLAGSETAEEKTIANKASSFSDVAEEETWHQQDELVG 1395



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 42/187 (22%), Positives = 72/187 (38%), Gaps = 22/187 (11%)

Query: 241  DKADAIVKMLDAAVIKMEGGT-ENDLRILEQEEEEEQAGKP--GEPSKKEEGRAGAGLGD 297
            D+ + + K LD A  + +    +  LR  + E EE         E + KEE +  A  G+
Sbjct: 1045 DRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGE 1104

Query: 298  GERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEA-----------K 346
             E +   ++E K    +  +D+ N+   + SE   +     EDS KE            +
Sbjct: 1105 TETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFE 1164

Query: 347  KSSKKRN--RKHSGDDSFDEGSVSESESESESGQAEE------EKEEAEEALKEKEKPKE 398
            KS +     RK  G +   E   +E +   E    E        +++ E AL   E    
Sbjct: 1165 KSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHRQDGEGALAAPEAEPA 1224

Query: 399  EEWEKPK 405
             + + P+
Sbjct: 1225 GKVQAPE 1231


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 30/107 (28%), Positives = 60/107 (56%)

Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358
           +++T + +E +E  ++ E +    +K K+   + +K++K +++EK  +K  +++ RK   
Sbjct: 7   KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66

Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPK 405
               +E    E E E E  + EEEKEE     K+K++ ++EE E+ K
Sbjct: 67  KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 34/111 (30%), Positives = 56/111 (50%), Gaps = 10/111 (9%)

Query: 305 KDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAK-KSSKKRNRKHSGDDSFD 363
           K +KKE  +  E + + +++ K+ +    ++EK+++ EK+ K K ++KR  K   +    
Sbjct: 4   KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63

Query: 364 EGSVSESESESESGQAEEEKEEAEEALKE---------KEKPKEEEWEKPK 405
                + E E    + EEE+EE EE  KE         K + KEEE EK K
Sbjct: 64  RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 3/95 (3%)

Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSK---KRNRKHSGDDSFDEGSVSESESESESGQAE 380
           K K++E   + EE +E+ EKE K+  K   KR  K     + +     E E E +  + +
Sbjct: 6   KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65

Query: 381 EEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
            +K++ EE  +E+E+ +EEE E+ +   G   K +
Sbjct: 66  RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 23/83 (27%), Positives = 44/83 (53%)

Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
           K KK +   + EE +E  E+E K+  +K  RK    +   +    E+E   E  + E+++
Sbjct: 3   KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62

Query: 384 EEAEEALKEKEKPKEEEWEKPKD 406
           +   +  KE+E+ +EEE E+ ++
Sbjct: 63  KRKRKKKKEEEEREEEEEEEEEE 85



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 7/63 (11%)

Query: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALK-------EKEKPKEEEWE 402
           KK+ +K    +  +E   +E E E E  + E+ KE+ +E  K       EK K KEEE +
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 403 KPK 405
           K K
Sbjct: 61  KRK 63



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 346 KKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE-EAEEALKEKEKPKEEEWEKP 404
           KK  KK+      +++ +     E E + +  + E+ KE E ++  KE EK KE+E E+ 
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 405 K 405
           K
Sbjct: 61  K 61



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 5/70 (7%)

Query: 336 EKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEK 395
           +KK+  +KE +++ +    +       +E      E   E  + +E+K++ +E  K KEK
Sbjct: 1   KKKKKKKKETEETEETEETEEE-----EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55

Query: 396 PKEEEWEKPK 405
            +EE+  K K
Sbjct: 56  EEEEKKRKRK 65



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 14/66 (21%), Positives = 33/66 (50%)

Query: 17  RRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPP 76
           R+E+ + ++ R+R  +++ ++    E +   E     E ++  R R+++    R E    
Sbjct: 52  RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111

Query: 77  QKRMRR 82
           +K+ RR
Sbjct: 112 KKKKRR 117


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 49/159 (30%), Positives = 73/159 (45%), Gaps = 14/159 (8%)

Query: 269  EQEEEEEQAGKPG-EPSKKEEGRAGAGLGDGE-RKTNDKDEKKEDGKQAENDSSNDDKTK 326
            EQE+E  + G+PG +P K++E R   G   G+ RK+   D + E+  Q  +   +++  +
Sbjct: 926  EQEKEAGEPGRPGTKPPKRDEER---GKTQGKHRKSFALDSEGEEASQESSSEKDEEDDE 982

Query: 327  KSEGDGDKEE-----KKE----DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
            + E D D+EE     KKE    D E E   SS K +     D   D  S SES S S S 
Sbjct: 983  EDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSS 1042

Query: 378  QAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRP 416
             +      +  +    E   E+E E+ + AA     P P
Sbjct: 1043 SSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPP 1081



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 37/165 (22%), Positives = 70/165 (42%), Gaps = 7/165 (4%)

Query: 279  KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK--QAENDSSNDDKTKKSEGDGDKEE 336
            K G  +  E    G+GL    R  + K ++KE  +  +A  +      T   E + D E+
Sbjct: 868  KSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQ 927

Query: 337  KKEDSE--KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE 394
            +KE  E  +   K  K+   +        +    +SE E  S ++  EK+E ++   E++
Sbjct: 928  EKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEED 987

Query: 395  KPKEE---EWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAE 436
            + +EE     +K  + +  E +       CSL+  +   N S ++
Sbjct: 988  EDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSD 1032



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 57/243 (23%), Positives = 83/243 (34%), Gaps = 67/243 (27%)

Query: 190  AHKDEEWFRSKYHPDEVGK------RRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKA 243
            A +DE+    +    E G+      +R E RG  Q + R   +L   G         ++A
Sbjct: 918  AEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEG---------EEA 968

Query: 244  DAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTN 303
                   +++  K E   E D    ++EE  +                          T 
Sbjct: 969  SQ-----ESSSEKDEEDDEEDEEDEDREEAVD--------------------------TT 997

Query: 304  DKDEKKEDGKQAENDSSND-DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSF 362
             K+ +  DG+  E+DSS+       S+G+ D     E S   +  SS           S 
Sbjct: 998  KKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSS-----------SS 1046

Query: 363  DEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE---------EWEKPKDAAGLECK 413
               S S S S SES   +EE+EE   AL     P  E         E   P+  AG    
Sbjct: 1047 SSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVT 1106

Query: 414  PRP 416
            P P
Sbjct: 1107 PLP 1109



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 26/68 (38%), Positives = 29/68 (42%), Gaps = 11/68 (16%)

Query: 755 TDAKRPALPEIKPAQPPGPAQSLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVP 814
           T  ++P  P   P  PP    SL  G P PHQ P  L+P   PRP       G   P  P
Sbjct: 599 TPPQQPPPPPPPPPPPPPYLASLPLGYP-PHQ-PAYLLP---PRPD------GPPPPEYP 647

Query: 815 TGGPPYPH 822
              PP PH
Sbjct: 648 PPPPPPPH 655


>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
           sapiens]
          Length = 1150

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 41/122 (33%), Positives = 61/122 (50%), Gaps = 16/122 (13%)

Query: 299 ERKTNDKDEKKED--GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356
           ++K  DK  KK++   K+ E D   D+   K    GD ++KKED ++  K+  +K     
Sbjct: 798 DKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRK----- 852

Query: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLE--CKP 414
             DDS D     + E+E ++ Q E +  EAEEA  E++   EEE  K  D   +   CK 
Sbjct: 853 --DDSKD-----DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKE 905

Query: 415 RP 416
           RP
Sbjct: 906 RP 907



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 3/90 (3%)

Query: 3   DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWND--REWDRGRERRSRGEYRDYDR 60
           + DDE D  +  K R+   D D+  +RDER++ D   D  ++ D   E  ++ EY   + 
Sbjct: 817 ERDDETDEPK-PKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEA 875

Query: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSD 90
              E     R E    ++  +RD + +  +
Sbjct: 876 EEAEDEEDDRDEEEMTKRDDKRDINRYCKE 905



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 4/60 (6%)

Query: 26  SRERDERRRGDDWNDREWDRGRER---RSRGEYRDYDRNRRERFSPPRHELSPPQKRMRR 82
           SR      RGD   +R+ DR RER   R R   R   R +R R   PR E     +R+RR
Sbjct: 299 SRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQR-KRSRERSPRRERERSPRRVRR 357


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 40/150 (26%), Positives = 72/150 (48%), Gaps = 7/150 (4%)

Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD-GERKTNDKDEKKEDGKQAENDSSNDD- 323
           +   + EEEE +      S+ E G      G+ GE   +++D  ++   + +++S  +  
Sbjct: 674 KFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESG 733

Query: 324 -KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382
            + K++     K + K DSE   K++ K +    S D+S    S+ +S S+SES    E 
Sbjct: 734 LENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDES---SSIEDSSSDSESESEPES 790

Query: 383 KEEAEEALKEKE-KPKEEEWEKPKDAAGLE 411
           + E+    KEKE K K++     KD + L+
Sbjct: 791 ESESRRVTKEKEKKTKQDRTPLTKDVSLLD 820



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 314 QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK-HSGDDSFDEGSVSESES 372
           +A+ ++S      +SE + D  +   DSE E+   S ++      GD + D    S SE 
Sbjct: 665 KAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQ 724

Query: 373 ESESGQAE--EEKEEAEEALKEKEKPKEEEWEKPKD 406
           +SESG+    E K  A+   K K K   E+ EK  +
Sbjct: 725 DSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENE 760



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 26/80 (32%), Positives = 35/80 (43%)

Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEK 393
           KE       K+   + K  +     +DS D  S SESES SESG+  E  EE +      
Sbjct: 658 KEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSS 717

Query: 394 EKPKEEEWEKPKDAAGLECK 413
           E    E+  +    +GLE K
Sbjct: 718 EDSSSEQDSESGRESGLENK 737



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 21/77 (27%), Positives = 33/77 (42%)

Query: 335 EEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE 394
           E  KE +     K      + +S  +  ++ S S S+SESESG    E+ E+ E     E
Sbjct: 655 ELAKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNE 714

Query: 395 KPKEEEWEKPKDAAGLE 411
              E+   +    +G E
Sbjct: 715 DSSEDSSSEQDSESGRE 731


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 34/104 (32%), Positives = 64/104 (61%), Gaps = 5/104 (4%)

Query: 302  TNDKDEKKEDGKQAENDSSNDDKTKKSEGDG-DKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
            + +++E++E+ ++ E +   +++ +K E +G +K+ +KE+ EK+ KK  KK+      ++
Sbjct: 2245 SEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304

Query: 361  SFDEGSVSESESESESGQAEEEKEEA----EEALKEKEKPKEEE 400
             F+E     SE E+ES   EEE+EE+    EE  +EKE  K+E+
Sbjct: 2305 VFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 26/143 (18%)

Query: 269  EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
            E+E EEE+  +  E  ++EE R              K+E++ + KQ E +     K KK 
Sbjct: 2248 EEEREEEEEREEEEVREEEEER--------------KEEEEGEEKQVEKEEEEKKKKKKE 2293

Query: 329  EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEE 388
            +   + +EK+E  E++ +  S++              S+S+ E E ES   EEE +  +E
Sbjct: 2294 KKKEEVQEKEEVFEEKEEIMSEEETE-----------SLSDEEEEEESCSLEEEVDREKE 2342

Query: 389  ALKEKEKPKEEEWEKPKDAAGLE 411
             LK++++ K +E ++ K   G E
Sbjct: 2343 ILKKEKQFKLQE-QRRKSLRGRE 2364



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 17/153 (11%)

Query: 267  ILEQEEE---EEQAGKPGEPSK-KEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322
            IL+ EEE   EE+   P    + ++   A  G    E+ ++  DE + +   +E   S  
Sbjct: 2175 ILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLL 2234

Query: 323  DKTKK-----SEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
            D+ +K     SE + ++EE++E  E+E ++  ++R  +  G    +E  V + E E +  
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEG----EEKQVEKEEEEKKKK 2290

Query: 378  QAEEEKEEA---EEALKEKEK-PKEEEWEKPKD 406
            + E++KEE    EE  +EKE+   EEE E   D
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEEETESLSD 2323



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 4/140 (2%)

Query: 271  EEEEEQAGKPGEPSKKEEGRAGAGLGDG----ERKTNDKDEKKEDGKQAENDSSNDDKTK 326
            EEE + A K  E    +E   G    +     +R+   + E K   K  E  SS  D+ +
Sbjct: 2162 EEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVE 2221

Query: 327  KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386
              E   ++ E   D  ++ +  S +   +   ++  +E  V E E E +  +  EEK+  
Sbjct: 2222 SEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281

Query: 387  EEALKEKEKPKEEEWEKPKD 406
            +E  ++K+K KE++ E+ ++
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQE 2301



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 100/512 (19%), Positives = 203/512 (39%), Gaps = 68/512 (13%)

Query: 262  ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA-ENDSS 320
            E + R+L++EE+  QAG+   P +             E    DK  K E+ KQ  EN  S
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEE-------------EMLQEDKKLKWEEWKQVWENMLS 1530

Query: 321  NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAE 380
            +  K ++ + + +   ++E S +  +K  +    +    +      +    + +E  +A+
Sbjct: 1531 SKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590

Query: 381  EEK---EEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEI 437
            EE+   +E E+  +E+ +  +EE +  +    +    R + +    F +       R E 
Sbjct: 1591 EERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEK 1650

Query: 438  IS------------LCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNI 485
            +S            L K++    +VA  E +  ++  +   V    +  ++E+    QN+
Sbjct: 1651 LSQEAEKLAQKRKKLAKKWE---KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707

Query: 486  RLRECELSPGVN------RDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWA 539
              +E EL+  +        +L+ +   +N   +  ++V    KLA       ++    W 
Sbjct: 1708 DWQEKELAQELEELEWDMEELSWKEEELN--QEEGKLVEEKKKLAE------EEEALAWQ 1759

Query: 540  SEPGTPPLPTSLPSQNPILKNITDYLIE--EVSAEEEELLGSSGGAPPEEPPKEGNPAEI 597
             E  +    T L  +  +L    + L +  E   EEEE LG       E+  K     E 
Sbjct: 1760 REKLSEE-ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818

Query: 598  NVERDEKLIKVLDKLLLYLRIVHSLDYYNTCE------YPNEDEMPNRCGIIHVRGPMPP 651
             +   E+L K  +K++LY +   + +  N  +         E+ + N+  + H +  +  
Sbjct: 1819 WINSMEELTK--NKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQ 1876

Query: 652  NRISHGEVLEWQKTFEEKLT----PLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQE 707
             +   G   +     EEKLT     ++  +E L+E E + +       +VE  +    ++
Sbjct: 1877 VKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLV-------QVEDSLAKKQEK 1929

Query: 708  LGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEK 739
            L ++K    L     +G + +R  +     EK
Sbjct: 1930 LAQEKMKLALEKAMVQGKKRLRGELDIAKEEK 1961



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 57/261 (21%), Positives = 111/261 (42%), Gaps = 39/261 (14%)

Query: 153  KEFLLSLDDSVDETEAVKRYNDYKLDFRRQQM--QDFFLAHKDEEWFRSKYHPDEVGKRR 210
            +E L+   + + + +      + +L  +R+Q+  +   LA K E W  S    +E+ K +
Sbjct: 1774 EELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSM---EELTKNK 1830

Query: 211  ----------QEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGG 260
                      QE +   Q + ++          +NLL + ++     K L    +K + G
Sbjct: 1831 MILYQKKNLAQEKKNLAQEKEKLAQRK------ENLLYNKERLTHSKKQL--VQVKNKLG 1882

Query: 261  TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERK---TNDKDEKKEDGKQAEN 317
              N  +IL Q EE+    K     KKE+      L + E+K     D   KK++    E 
Sbjct: 1883 MFN--KILAQVEEKLTQEKETVIKKKEK------LAETEKKLVQVEDSLAKKQEKLAQEK 1934

Query: 318  DSSNDDKT-----KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372
                 +K      K+  G+ D  ++++    E K+ ++++ R   G ++  +G   E+  
Sbjct: 1935 MKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSR 1994

Query: 373  ESESGQAEEEKEEAEEALKEK 393
            + +  Q E+E  E + +L+EK
Sbjct: 1995 QRKMTQVEQELFERKLSLEEK 2015



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 40/132 (30%), Positives = 58/132 (43%), Gaps = 23/132 (17%)

Query: 285  KKEEGRAGAGLGDGERKTNDKDEK--KEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE 342
            +K+  R    L +  R+  +K+EK  +E+ K A          K SE   D EE+    E
Sbjct: 2136 EKKLARKQRKLANKMRRMINKEEKMTEEESKLAR---------KHSEVILDDEEEGGIEE 2186

Query: 343  KEA----KKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPK- 397
            +E     K+  +KR     GD   ++ S    E ESE    E   EE E  L E EK + 
Sbjct: 2187 EEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESE----EHFSEEMESLLDELEKQES 2242

Query: 398  ---EEEWEKPKD 406
               EEE E+ ++
Sbjct: 2243 LSSEEEEEREEE 2254



 Score = 30.0 bits (66), Expect = 9.7
 Identities = 19/85 (22%), Positives = 43/85 (50%)

Query: 270  QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE 329
            ++EEEE+  K  E  K+E         + E   ++++ +    ++ E +S + ++    E
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340

Query: 330  GDGDKEEKKEDSEKEAKKSSKKRNR 354
             +  K+EK+   +++ +KS + R R
Sbjct: 2341 KEILKKEKQFKLQEQRRKSLRGRER 2365


>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
           [Homo sapiens]
          Length = 845

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 67/261 (25%), Positives = 119/261 (45%), Gaps = 33/261 (12%)

Query: 148 VMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVG 207
           + KTF E L   D    E E V +  + +   ++QQ +      +D    R K   D+ G
Sbjct: 37  IKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKK----KRDTRKGRRKKDVDDDG 92

Query: 208 KRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRI 267
           + ++     L  RL+  LS+  +          D+ D +         K +GG      I
Sbjct: 93  EEKE-----LMERLKK-LSVPTS----------DEEDEVPAPKPRGGKKTKGGNVFAALI 136

Query: 268 LEQ-EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326
            +Q EEEEE+   P +P+K E+ R    + + ++       K + GK+ ++      + K
Sbjct: 137 QDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPA----LKGKKGKEEKSKGKAKPQNK 192

Query: 327 KSEGDGDKEEKKED--SEKEAKKSSKKRNRK-HSGDDSFDEGSVSESESESESGQAEEEK 383
            +  D ++E+K+E+   EKE  K  K++ +K   G +   EG     E E E G+++ + 
Sbjct: 193 FAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEG----EEEEEEGGESKADD 248

Query: 384 EEAEEALKEKEKPKEE-EWEK 403
             A  + KEK+K K++ E+E+
Sbjct: 249 PYAHLSKKEKKKLKKQMEYER 269



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 38/173 (21%), Positives = 69/173 (39%), Gaps = 35/173 (20%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
           +Q  E E  G  GE +   +     G  D + K    +E   + KQA      ++K  K 
Sbjct: 7   QQPPEPEWIGD-GESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQA----GEEEKVLKE 61

Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEG---------SVSESESESE---- 375
           +   +++++++  +++ K+ ++K  RK   DD  +E          SV  S+ E E    
Sbjct: 62  K---EQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAP 118

Query: 376 --------------SGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKP 414
                         +   +++ EE EE  K   KP + E  +   A   E +P
Sbjct: 119 KPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQP 171


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 38/160 (23%), Positives = 78/160 (48%), Gaps = 10/160 (6%)

Query: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE--RKTNDKDEKKEDGKQAEND 318
           T+ D + L+++++++   K  E +  E G A     D    +K +  D+KK+D K+    
Sbjct: 347 TKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFS 406

Query: 319 SSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
           + ++ + +  E   D+++ K+DS+ + KKS K        D        SE + +S+ G+
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDAD--------SEPKGDSKKGK 458

Query: 379 AEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLH 418
            +E+K + +    +K+K  ++  E  +  + LE K    H
Sbjct: 459 KDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH 498



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 63/268 (23%), Positives = 107/268 (39%), Gaps = 31/268 (11%)

Query: 161 DSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNR 220
           D   +TE+    +    D R+   +D     KD++   +K +P+       +A+ A  + 
Sbjct: 325 DVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDS 384

Query: 221 LRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKP 280
                           L    K D   K  DA  I     +E++L   E +++E++  K 
Sbjct: 385 RN--------------LKKASKNDD--KKKDAKKITFSTDSESELESKESQKDEKKDKKD 428

Query: 281 GEPSKKEEGRAGAGLGDGERKTNDKDEK-KEDGKQAENDSSNDDKTK-------KSEGDG 332
            +   K+  +      D + +     +K K+D K+ + DS  DDK K        +E + 
Sbjct: 429 SKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMES 488

Query: 333 DKEEKKEDSEKEAKKSSKK------RNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386
           D E KK+    + KK SKK      R    S D  FDE S +  ++ ++   ++ E EE+
Sbjct: 489 DLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEES 548

Query: 387 EEALKEKEKPKEEEWEKPKD-AAGLECK 413
                 K+K  E +         GLE K
Sbjct: 549 LYKPGAKKKIDESDGTSANSKMEGLESK 576



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 5/137 (3%)

Query: 265 LRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDK 324
           LR   Q   +  + K  + +KK+  +      D E  + D  + K+D K+ + +   DDK
Sbjct: 265 LRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAE--SEDSKDAKKDSKKVKKNVKKDDK 322

Query: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384
            K  + D +  + +    K+ +K +KK  +K   DD   +       +++ESG A++ + 
Sbjct: 323 KKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARN 382

Query: 385 EA---EEALKEKEKPKE 398
           ++   ++A K  +K K+
Sbjct: 383 DSRNLKKASKNDDKKKD 399



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 38/164 (23%), Positives = 75/164 (45%), Gaps = 27/164 (16%)

Query: 271 EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQ------AENDSSNDDK 324
           +++ ++  K    ++ E+ +         +K   KD+KK+D K+      AE+  S D++
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDER 344

Query: 325 --TKKSEGDGDKEEKKEDSE-------------KEAKKSSKKRNRKHSGDDSFDE----- 364
             TKK +    K++KK+D++             K+A+  S+   +    DD   +     
Sbjct: 345 KDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT 404

Query: 365 -GSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDA 407
             + SESE ES+  Q +E+K++ +     K+  K +E     D+
Sbjct: 405 FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADS 448



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 21/147 (14%)

Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN---DDKTKKSEGDGDKE 335
           K  E  K ++ + G  L         KD KK+ G  A N  S    ++KTK+ + + DK 
Sbjct: 111 KKAEYKKSKDEKGGTPL--------KKDSKKKGGSYATNPESKQIVEEKTKR-QNEADKT 161

Query: 336 EKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEK 395
             K   E E  K SK  +   +  +S +  +VS++ S+ +   ++  K+   E L  K  
Sbjct: 162 PLKSSHENEQSKKSK--SSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNN 219

Query: 396 PKEEEWEKPKDAAGLECKPRPLHKTCS 422
           PK       KD    +    P+ + CS
Sbjct: 220 PK-------KDLKRSKTSNDPISEICS 239



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 14/98 (14%)

Query: 317 NDSSNDDK------TKKSEGDGDKEEKKE-----DSEKEAKKSSKKRNRKHSGDDSFDEG 365
           N S N+ K      TK ++ D  K  KK      +  K+AKK SKK  +    DD   + 
Sbjct: 267 NYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDV 326

Query: 366 SVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
                 +++ESG   + K+E ++  K+K+K K+++ +K
Sbjct: 327 KKDTESTDAESG---DSKDERKDTKKDKKKLKKDDKKK 361



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 10/109 (9%)

Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKK-EDSEKEAKKSSKKRNRKHS 357
           E+K + KD KK+  K  E+  +  D++ K+   G K   K + S+ E+++S  K   K  
Sbjct: 501 EKKGSKKDIKKDARKDTESTDAEFDESSKT---GFKTSTKIKGSDTESEESLYKPGAKKK 557

Query: 358 GDDSFDEGSVSESES-ESESGQAEEEK-----EEAEEALKEKEKPKEEE 400
            D+S    + S+ E  ES+ G     K     E+ E+A   +  P  E+
Sbjct: 558 IDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREK 606


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 37/157 (23%), Positives = 78/157 (49%), Gaps = 4/157 (2%)

Query: 260 GTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319
           G ++++R  E+E E  + GK    S++++ R      +  ++  +K+ K+E GK+ +   
Sbjct: 33  GWQSEIREREREIETRKEGKKERESERKKERRER---EKRKREREKERKRERGKKEKKGE 89

Query: 320 SNDDKTKKSEGDGDKEEKK-EDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
              ++ ++ +   +KE K+ E+ EK  KK  K+R R        +     + E   E  +
Sbjct: 90  RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149

Query: 379 AEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
            +EE+E+  E  + K++ +++  EK ++    E K R
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 40/150 (26%), Positives = 72/150 (48%), Gaps = 12/150 (8%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
           E++ E  +  K GE  K+E  R         ++  +K+++K+  K+    +S + K ++ 
Sbjct: 76  ERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135

Query: 329 EGDGDKEEKKE------DSEKE-AKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
           + +  +EE+KE      + EKE  +K  KKR RK  G+   +       E +      +E
Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195

Query: 382 EKEEAE-----EALKEKEKPKEEEWEKPKD 406
            K+E E     E  KE++K +E + E+ KD
Sbjct: 196 RKKERERKERRERKKERKKKEERKKERQKD 225



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 34/154 (22%), Positives = 77/154 (50%), Gaps = 4/154 (2%)

Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN 321
           E + +   +E+E ++  +  +  KKE+   G    +G+ +   ++ K+E+ K+ E     
Sbjct: 94  ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153

Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
            +K ++ + +  K E+K+  EKE ++  K+R  +   + +  E    +     E  + ++
Sbjct: 154 REKERERK-ERKKRERKQVGEKEEERKEKERKERKKRERNRKER--KKERERKERRERKK 210

Query: 382 EKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
           E+++ EE  KE++K ++  W + K+    E K R
Sbjct: 211 ERKKKEERKKERQKDRQTNW-REKERGKRERKER 243



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 11/166 (6%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
           + EG  E +    ++  E E+  +  E  +K E   G     GERK  +++ KK   ++ 
Sbjct: 48  RKEGKKERESERKKERREREKRKREREKERKRE--RGKKEKKGERKKEERERKKRR-REK 104

Query: 316 ENDSSND-----DKTKKSEGDGDKEEKKEDSEKEAKKSSKK-RNRKHSGDDSFDEGSVSE 369
           EN    +      K KK  G   KE K+ + ++E K+  +K R RK    +   E    +
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164

Query: 370 SESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
                + G+ EEE++E E   KE++K +    E+ K+    E + R
Sbjct: 165 KRERKQVGEKEEERKEKER--KERKKRERNRKERKKERERKERRER 208



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 6/137 (4%)

Query: 276 QAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK---QAENDSSNDDKTKKSEGDG 332
           Q G   E  ++E        G  ER++  K E++E  K   + E +   +   K+ +G+ 
Sbjct: 31  QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90

Query: 333 DKEE---KKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEA 389
            KEE   KK   EKE K+  +K  RK          S    E E +  +  EE++E E  
Sbjct: 91  KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150

Query: 390 LKEKEKPKEEEWEKPKD 406
            +E+EK +E +  K ++
Sbjct: 151 KEEREKERERKERKKRE 167



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 31/146 (21%), Positives = 73/146 (50%), Gaps = 9/146 (6%)

Query: 260 GTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319
           G E + R  ++++E  +  K G+  +++E R      + ERK   K+E++++ ++ E   
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK---KEEREKERERKERKK 165

Query: 320 SNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQA 379
               +  + E +  ++E+KE  ++E  +  +K+ R+        E    + E + +  + 
Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERK------ERRERKKERKKKEERK 219

Query: 380 EEEKEEAEEALKEKEKPKEEEWEKPK 405
           +E +++ +   +EKE+ K E  E+ K
Sbjct: 220 KERQKDRQTNWREKERGKRERKERKK 245



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 21/85 (24%), Positives = 43/85 (50%)

Query: 6   DEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRER 65
           +E  R  R +  R++ + ++ RER ER++ +     E +  R+ + R E +  +RNR+ER
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196

Query: 66  FSPPRHELSPPQKRMRRDWDEHSSD 90
                 +    +K+ R+  +E   +
Sbjct: 197 KKERERKERRERKKERKKKEERKKE 221



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 7   EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERF 66
           E  +RRR+K  +E  + ++ ++++++ RG     R    G+ER  + E +  +R  RER 
Sbjct: 96  ERKKRRREKENKEGEEKEKRKKKEKKERG-----RTSKEGKERERKEERKREERKERERK 150

Query: 67  SPPRHELSPPQKRMRRD 83
              R +    ++R +R+
Sbjct: 151 KEEREKERERKERKKRE 167



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%)

Query: 7   EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRS--RGEYRDYDRNRRE 64
           E +R+ R K  R R +  + RER ERR       ++ +R +ER+   +  +R+ +R +RE
Sbjct: 180 EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRE 239

Query: 65  R 65
           R
Sbjct: 240 R 240



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 17/63 (26%), Positives = 37/63 (58%), Gaps = 1/63 (1%)

Query: 3   DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNR 62
           +S+ + +RR R+K +RER + +R RER ++ +  +    E +R + RR +      ++ +
Sbjct: 56  ESERKKERREREKRKRER-EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114

Query: 63  RER 65
           R++
Sbjct: 115 RKK 117



 Score = 33.9 bits (76), Expect = 0.67
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 8/66 (12%)

Query: 3   DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER---RSRGEYRDYD 59
           + + E + R+  K  RE       RER++R+R     +RE +R RER     +GE +  +
Sbjct: 40  EREREIETRKEGKKERESERKKERREREKRKR-----EREKERKRERGKKEKKGERKKEE 94

Query: 60  RNRRER 65
           R R++R
Sbjct: 95  RERKKR 100



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 5/79 (6%)

Query: 3   DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNR 62
           + + E   +R+ K ++ER     S+E  ER R +   +R+ +  +ER  + E R+ +R R
Sbjct: 106 NKEGEEKEKRKKKEKKERG--RTSKEGKERERKE---ERKREERKERERKKEEREKERER 160

Query: 63  RERFSPPRHELSPPQKRMR 81
           +ER    R ++   ++  +
Sbjct: 161 KERKKRERKQVGEKEEERK 179



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 7   EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGE-----YRDYDRN 61
           E  R  ++   RER +  +  ER ER R  +  +RE +R R+ R + E      ++ +R 
Sbjct: 122 ERGRTSKEGKERERKEERKREERKERERKKE--EREKERERKERKKRERKQVGEKEEERK 179

Query: 62  RRERFSPPRHELSPPQKRMRRDWDE 86
            +ER    + E +  +++  R+  E
Sbjct: 180 EKERKERKKRERNRKERKKERERKE 204



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)

Query: 25 RSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDW 84
          R RER+   R +   +RE +R +ERR R      ++ +RER    + E    +K+  R  
Sbjct: 39 REREREIETRKEGKKERESERKKERRER------EKRKREREKERKRERGKKEKKGERKK 92

Query: 85 DE 86
          +E
Sbjct: 93 EE 94


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 39/150 (26%), Positives = 76/150 (50%), Gaps = 13/150 (8%)

Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
           +G  E + + +E+E  E +  +  E  ++E  R          +  +++ +KE  ++ E 
Sbjct: 295 KGKKEKERQEIEKERRERERERERERERRERER---------EREREREREKEKERERER 345

Query: 318 DSSND-DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESES 376
           +   D D+TK+ + D D+E  + D ++E + S + ++R  S + S D     E E E E 
Sbjct: 346 ERDRDRDRTKERDRDRDRERDR-DRDRE-RSSDRNKDRSRSREKSRDRERERERERERER 403

Query: 377 GQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
            + E E+E   E  +E+E+ +E E +K +D
Sbjct: 404 -EREREREREREREREREREREREKDKKRD 432



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 47/228 (20%), Positives = 97/228 (42%), Gaps = 26/228 (11%)

Query: 204 DEVGKRRQEARGALQNRLRVFLSLM-----ETGWFDNLLLDIDKADAIVKMLDAAVIKME 258
           +E  +R Q  +GA++  +R + S +     E+           K D   +   A +I   
Sbjct: 198 EETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYP 257

Query: 259 GGTENDLRILEQEEE-------------------EEQAGKPGEPSKKEEGRAGAGLGDGE 299
             T+ D+  +E EE+                   EE+ GK  +  ++ E        + E
Sbjct: 258 LITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERE 317

Query: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGD 359
           R+   ++ ++E  ++ E +   + + ++ E D D++  KE      ++  + R+R+ S D
Sbjct: 318 RERERREREREREREREREKEKE-RERERERDRDRDRTKERDRDRDRERDRDRDRERSSD 376

Query: 360 DSFDEGSVSESESESE-SGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
            + D     E   + E   + E E+E   E  +E+E+ +E E E+ ++
Sbjct: 377 RNKDRSRSREKSRDRERERERERERERERERERERERERERERERERE 424



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 34/160 (21%), Positives = 71/160 (44%), Gaps = 17/160 (10%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
           E+E E E+         KE  R      D +R      ++ +D  ++   S + ++ ++ 
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER 397

Query: 329 EGDGDKEEKKE---DSEKE-------AKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
           E + ++E ++E   + E+E        ++  KKR+R+   +D+++   +     E E+  
Sbjct: 398 EREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAY 457

Query: 379 AE-------EEKEEAEEALKEKEKPKEEEWEKPKDAAGLE 411
            E        E+++  E  KE E+ +E   E  K+A  L+
Sbjct: 458 QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 497



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 33/143 (23%), Positives = 70/143 (48%), Gaps = 11/143 (7%)

Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER-KTNDKDEKKEDGKQAENDSS 320
           E + R  E+E E E+  +  +  ++E  R      D +R K  D+D  +E  +  + + S
Sbjct: 319 ERERREREREREREREREKEKERERERERDR----DRDRTKERDRDRDRERDRDRDRERS 374

Query: 321 ND---DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
           +D   D+++  E   D+E ++E   +  ++  ++R R+   +   +     E + + +  
Sbjct: 375 SDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDR- 433

Query: 378 QAEEEKEEAEEALKEKEKPKEEE 400
             EE++E+A E  K + K +E+E
Sbjct: 434 --EEDEEDAYERRKLERKLREKE 454



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 3/91 (3%)

Query: 3   DSDDEYDRRR-RDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDR 60
           + + E +R R RD+ R +  D DR RERD  R  +  +DR  DR R R +SR   R+ +R
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER 397

Query: 61  NR-RERFSPPRHELSPPQKRMRRDWDEHSSD 90
            R RER      E    ++R R    E   D
Sbjct: 398 EREREREREREREREREREREREREREREKD 428



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 9/84 (10%)

Query: 7   EYDRRRRDKFR---RERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDRNR 62
           E +RR R++ R   RER + +R RER+  R  +   +RE +R R+R R++   RD DR R
Sbjct: 306 EKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 365

Query: 63  -----RERFSPPRHELSPPQKRMR 81
                RER S    + S  +++ R
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSR 389



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 29/147 (19%), Positives = 70/147 (47%), Gaps = 9/147 (6%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER-----KTNDKDEKKEDGKQAENDSSND- 322
           ++E + ++  +      K+  R+     D ER     +  +++ ++E  ++ E +   + 
Sbjct: 362 DRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERER 421

Query: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE-SGQAEE 381
           ++ ++ +   D+EE +ED+ +  K   K R ++ +  +      + E +   E   +AE 
Sbjct: 422 EREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAER 481

Query: 382 EKEEAEEALKEKEKPKE--EEWEKPKD 406
           E+E   E  KE ++ KE  E+++  +D
Sbjct: 482 EEERRREMAKEAKRLKEFLEDYDDDRD 508



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 32/145 (22%), Positives = 66/145 (45%), Gaps = 12/145 (8%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
           E E+E E+  +      KE  R    L D +   +D+D+ K     A      D + +  
Sbjct: 474 EYEKEAEREEERRREMAKEAKRLKEFLEDYD---DDRDDPKYYRGSALQKRLRDREKEME 530

Query: 329 EGDGDKEEKKEDSEKEAKK---------SSKKRNRKHSGDDSFDEGSVSESESESESGQA 379
             + D++ +KE+ E+  ++          ++ +  +   +         E ESE E  + 
Sbjct: 531 ADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEK 590

Query: 380 EEEKEEAEEALKEKEKPKEEEWEKP 404
           +E++E+ EE ++E+E+P+++   KP
Sbjct: 591 QEKEEKREEPMEEEEEPEQKPCLKP 615



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 31/91 (34%), Positives = 44/91 (48%), Gaps = 13/91 (14%)

Query: 3   DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-----------RS 51
           + + E +R R  +  RER + +R R+RD  +  D   DRE DR R+R           RS
Sbjct: 326 EREREREREREKEKERER-ERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRS 384

Query: 52  RGEYRDYDRNR-RERFSPPRHELSPPQKRMR 81
           R + RD +R R RER      E    ++R R
Sbjct: 385 REKSRDRERERERERERERERERERERERER 415



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 41/175 (23%), Positives = 80/175 (45%), Gaps = 13/175 (7%)

Query: 264 DLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD 323
           ++R  ++  E E+  +  E  ++E  +    L   +    D D+ ++D K     S+   
Sbjct: 465 EIRERKKTREYEKEAEREEERRREMAKEAKRL---KEFLEDYDDDRDDPKYYRG-SALQK 520

Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
           + +  E + + +E+    EKE  +  ++R       D   E    E E+E       +++
Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQE 580

Query: 384 EEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC---SLFMRNIAPNISRA 435
            E+EE  +EK++ KEE+ E+P     +E +  P  K C   +L   + AP++S A
Sbjct: 581 PESEEEEEEKQE-KEEKREEP-----MEEEEEPEQKPCLKPTLRPISSAPSVSSA 629



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 9/83 (10%)

Query: 11  RRRDKFRRERSDYDRSRERD-ERRRGDDWNDREWDRGRER-RSRGEYRDYDRNRRERFSP 68
           + R +  +ER + +R RER+ ERR  +   +RE +R +E+ R R   RD DR+R +    
Sbjct: 300 KERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR 359

Query: 69  PRHELSPPQKRMRRDWD-EHSSD 90
            R       +   RD D E SSD
Sbjct: 360 DR------DRERDRDRDRERSSD 376



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 1/89 (1%)

Query: 3   DSDDEYDRRRRDKFRRERS-DYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRN 61
           D + E +R R  +  RER  + +R RER+  R  +   D++ DR  +     E R  +R 
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449

Query: 62  RRERFSPPRHELSPPQKRMRRDWDEHSSD 90
            RE+ +  +  L   + R R+   E+  +
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKE 478



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 4   SDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDRNR 62
           SD   DR R  +  R+R + +R RER+  R  +   +RE +R RER R R   +D  R+R
Sbjct: 375 SDRNKDRSRSREKSRDR-EREREREREREREREREREREREREREREREREREKDKKRDR 433

Query: 63  RE 64
            E
Sbjct: 434 EE 435



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 6/134 (4%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
           E+E E E+  +  +   +EE    A     ER+  ++  ++++    E   + + + +K 
Sbjct: 416 EREREREREREKDKKRDREEDEEDAY----ERRKLERKLREKEAAYQERLKNWEIRERKK 471

Query: 329 EGDGDKEEKKEDSEKE--AKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386
             + +KE ++E+  +   AK++ + +      DD  D+       +  +  +  E++ EA
Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA 531

Query: 387 EEALKEKEKPKEEE 400
           +E  +++EK + EE
Sbjct: 532 DERDRKREKEELEE 545



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 25/116 (21%)

Query: 3   DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGR--------------- 47
           + + E +R R  +  RER + +R RE+D++R  ++  +  ++R +               
Sbjct: 402 ERERERERERERERERER-EREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQER 460

Query: 48  ----ERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMR---RDWDEHSSDP-YHSG 95
               E R R + R+Y++   ER    R E++   KR++    D+D+   DP Y+ G
Sbjct: 461 LKNWEIRERKKTREYEK-EAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG 515



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 5/60 (8%)

Query: 11  RRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-----RSRGEYRDYDRNRRER 65
           R R++ R    + +R RER+  R  +   +RE +R RE+     R   E   Y+R + ER
Sbjct: 389 RDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 7/59 (11%)

Query: 6   DEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRE 64
           D + +   +K ++E+   +  +ER ER       +RE +R RERR R   R+ +R R +
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRER-------ERERERERERREREREREREREREK 337


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 50/186 (26%), Positives = 82/186 (44%), Gaps = 22/186 (11%)

Query: 251 DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310
           DA   + E   + +++   +EEE+ Q  K  EP KK E        + +     K E+K+
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE--------EEKAPATPKTEEKK 857

Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK------------HSG 358
           D K+ E       K K  E      EK ++S+ EAKK   +  +K               
Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK 917

Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAE--EALKEKEKPKEEEWEKPKDAAGLECKPRP 416
           +D+  +     ++ E +  +A+E  + AE  EA  EK+  KEE+ +KP++    E K + 
Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKE 977

Query: 417 LHKTCS 422
             KT S
Sbjct: 978 DDKTLS 983



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 45/175 (25%), Positives = 81/175 (46%), Gaps = 15/175 (8%)

Query: 246 IVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEG--RAGAGLGDGERKTN 303
           +V+  +   + +E  TE + ++ E+  EEE+     E  K+EEG     A  G+ E K+ 
Sbjct: 446 VVEKSEKETVIVEEQTE-ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP 504

Query: 304 DKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD 363
             +E     K+A++    + K+       +KEE K  +E ++ + +K   ++        
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE------- 557

Query: 364 EGSVSESESESESGQAEEEKEEAEEALKEKEK-PKEEEWEKPKDAAGLECKPRPL 417
               ++S  E++S + EE K  AE    EK K P +EE + P +A   E    P+
Sbjct: 558 ----AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 6/152 (3%)

Query: 269  EQEEEEEQAGKPGEPSKK-EEGRAGAGLGDGERKTNDKDEKKEDGKQA---ENDSSNDDK 324
            +++ ++E+A K   P  K EE +  A     E K   K E+ ED K+    E ++    +
Sbjct: 856  KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915

Query: 325  TKKSEGDGDKEE--KKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382
             K+     +K E  KKE  + +AK+ SK   +K +  +  D       + E +     + 
Sbjct: 916  VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKA 975

Query: 383  KEEAEEALKEKEKPKEEEWEKPKDAAGLECKP 414
            KE+ +   KE  KPK E+ EK       + KP
Sbjct: 976  KEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 34/166 (20%)

Query: 247 VKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKD 306
           +K+     IK+   +E +  I+E++ EE Q  +  E +++EE                K+
Sbjct: 436 IKVKSEEKIKVVEKSEKETVIVEEQTEETQVTE--EVTEEEE----------------KE 477

Query: 307 EKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS 366
            K+E+GK+ E     + +  + E      E+    EKEAK   K+               
Sbjct: 478 AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEE-------------- 523

Query: 367 VSESESESESGQAEEEKEEAEEALKEKEK-PKEEEWEKPKDAAGLE 411
            ++S +E++S + EE K  AE    EK K P +EE + P +A   E
Sbjct: 524 -AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 40/141 (28%), Positives = 61/141 (43%), Gaps = 8/141 (5%)

Query: 274 EEQAGKPGEPS--KKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
           +E+A  P E    +KEE ++ A +   E+    K   KE+ K      S + +  KS  +
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKA---KSPAKEEAKSPPEAKSPEKEEAKSPAE 577

Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALK 391
               EK +   KE  KS  +            E   ++S +E++S   EE K  AE    
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE--EAKSPAEAKSPVKEEAKSPAEVKSP 635

Query: 392 EKEK-PKEEEWEKPKDAAGLE 411
           EK K P +EE + P+ A   E
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPE 656



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 15/148 (10%)

Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSK------KEEGRAGAGLGDGERKTNDKDEKKED 311
           EGG E +    E+E +   A +   P K      KEE ++ A     E K+ +K+E K  
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA-----EAKSPEKEEAKSP 541

Query: 312 GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE 371
              AE  S    K+   E      E K   ++EAK  ++ ++ + +   + +E   S +E
Sbjct: 542 ---AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK-SPAE 597

Query: 372 SESESGQAEEEKEEAEEALKEKEKPKEE 399
           ++S        KEEA+   + K   KEE
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEE 625



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 11/177 (6%)

Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEE--EEQAGKPGEPSKKEEGRAGAGLGDG 298
           +KA + VK    +  K +   + + +  E+ +   +E+A  P E +K  E      +   
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP-EKAKSPEKAKTLDVKSP 764

Query: 299 ERKTNDKDEKKEDGKQ--------AENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSK 350
           E KT  K+E +    +         + +  + +K K    +  K  +KE  +KE  KS  
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824

Query: 351 KRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDA 407
           K   K       +    +E E    + + EE+K+  +E   +KE PK +  EK + A
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 15/156 (9%)

Query: 273 EEEQAGKPGEPSKKEEGRAGA---GLGDGERKTNDKDEKKE--DGKQAENDSSNDDKTKK 327
           E+E+A  P E    E+ ++ A        E K+ +K+E K   + K  E   S   +  K
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593

Query: 328 SEGDGDKEEK-KEDSEKEAK-----KSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
           S  +    EK K   ++EAK     KS  K   K   +    E + S ++ E++S +  +
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653

Query: 382 --EKEEAEEALKEKEKPKEE--EWEKPKDAAGLECK 413
             EKEEA+   K K   K E    EK K     E K
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)

Query: 275 EQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDK 334
           E+A  P +   K   +A + L +  +    +  KKE+ K    +     + K  E     
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842

Query: 335 EEKKEDS--EKEAKKSSKKRN--RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEAL 390
           EE+K  +  + E KK SKK    +K +     +E      E   ES + E +KEEAE+  
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES-KVEAKKEEAED-- 899

Query: 391 KEKEKPKEEEWEKPKDAAGLECKPR 415
            +K+ P  E+    K     + KP+
Sbjct: 900 -KKKVPTPEKEAPAKVEVKEDAKPK 923



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 4/136 (2%)

Query: 274 EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGD 333
           +E+A  P E    E+ ++     + +     K   KE+ K      S +     ++ +  
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVK-EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK 647

Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE--KEEAEEALK 391
             EK +  EKE  KS +K       +    E + S  ++E++S +  +   KEEA+   K
Sbjct: 648 SPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEK 707

Query: 392 EKEKPKEEEWEKPKDA 407
            K  P +EE + P+ A
Sbjct: 708 AK-SPVKEEAKSPEKA 722



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 14/149 (9%)

Query: 274 EEQAGKPGEPSK--KEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
           +E+A  P E     KEE ++ A +   E+    K   KE+ K  E   S + +  KS   
Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKA---KSPTKEEAKSPEKAKSPEKEEAKSPEK 665

Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK--EEAEEA 389
                K E    E  KS  K   K            ++S  +++S   EE K  E+A+  
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725

Query: 390 LKEKEK-------PKEEEWEKPKDAAGLE 411
           +KE+ K       P +EE + P+ A   E
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 18/154 (11%)

Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGER-KTNDKDEK----------------KEDGKQ 314
           +EE ++    +  +KEE ++ A +   E+ K+  K+E                 KE+ K 
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614

Query: 315 AENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES 374
                S   +  KS  +    EK +   KE  KS +K       +    E + S  ++E+
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674

Query: 375 ESGQAEEEKEEAEEALKEKEK-PKEEEWEKPKDA 407
           +S +  +   +AE    EK K P +EE + P+ A
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 33/145 (22%), Positives = 53/145 (36%), Gaps = 5/145 (3%)

Query: 274 EEQAGKPGE---PSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEG 330
           +E+A  P E   P K +           + K+ +K+E K   K      +     +K++ 
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682

Query: 331 DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES--ESESGQAEEEKEEAEE 388
               E K  +  K   K   K   K       +  S  +++S  + E+   E+ K   +E
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742

Query: 389 ALKEKEKPKEEEWEKPKDAAGLECK 413
             K  EK K  E  K  D    E K
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAK 767



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 2/137 (1%)

Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
           +EE ++ +  +  +KEE ++        +      EK +   +AE  S    K+   E  
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702

Query: 332 GDKEEKKEDSEKEAKKSSKKRN--RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEA 389
              E+ K   ++EAK   K ++  ++ +      +  V E     E  ++ E+ +  +  
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762

Query: 390 LKEKEKPKEEEWEKPKD 406
             E + P +EE   P D
Sbjct: 763 SPEAKTPAKEEARSPAD 779



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 14/135 (10%)

Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
           +EE ++ +  +   KEE ++       E+  +   E+ +  ++A++    + K+ +    
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSP------EKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS 752

Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALK 391
            +K +  +    EAK  +K+  R  S  D F E + S  + E +S       E+A+  LK
Sbjct: 753 PEKAKTLDVKSPEAKTPAKEEAR--SPADKFPEKAKSPVKEEVKS------PEKAKSPLK 804

Query: 392 EKEKPKEEEWEKPKD 406
           E  K  E+E  K ++
Sbjct: 805 EDAKAPEKEIPKKEE 819


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 47/182 (25%), Positives = 83/182 (45%), Gaps = 8/182 (4%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
           K E G E + +  E+E++ ++  +     +K+E +       G R+   K E+KE  ++ 
Sbjct: 68  KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE--RER 125

Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
           EN    + K KK      ++E+K + E+  K+  K++ RK    +   E +  E + E E
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRERNRKERKKERE 184

Query: 376 SGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRA 435
             +  E K+E +   KE+ K KE + ++  D        RPL +  S F R     + R 
Sbjct: 185 RKERRERKKERK---KERRKKKERKKDRKTDRQTDSQVFRPLRE--SAFNRVTVTGVFRY 239

Query: 436 EI 437
            I
Sbjct: 240 RI 241



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 34/138 (24%), Positives = 66/138 (47%), Gaps = 6/138 (4%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
           +++ ++ + GK  E  +KE  +      + ER+   K++KK + KQ        ++ KK 
Sbjct: 63  KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ----RGRRERKKKK 118

Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEE 388
           E    + E K+  E++ KK  KK+ RK    +   E    E + +    +  E+K E   
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREK--ERGKRERKRKKRKKEEREKKRERNR 176

Query: 389 ALKEKEKPKEEEWEKPKD 406
             ++KE+ ++E  E+ K+
Sbjct: 177 KERKKERERKERRERKKE 194



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 29/147 (19%), Positives = 76/147 (51%), Gaps = 2/147 (1%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
           ++E E+E+  + G+  KK+  +   G  + ERK  ++++++++ ++ E      +K K+ 
Sbjct: 47  KREREKERKRERGKKEKKKRKKRERGK-ERERKRKEREKQRKERREKERRKRKKEKKKRE 105

Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEE 388
                + E+K+  E++ ++   K+ R+        +    E + E E G+ E ++++ ++
Sbjct: 106 RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK 165

Query: 389 ALKEKEKPKEEEWEKPKDAAGLECKPR 415
             +EK++ +  + E+ K+    E + R
Sbjct: 166 EEREKKRERNRK-ERKKERERKERRER 191



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 32/136 (23%), Positives = 62/136 (45%), Gaps = 16/136 (11%)

Query: 271 EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEG 330
           + E E+  +  E  K++  R      +  +K   K +K+E GK+ E         K+ E 
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER--------KRKER 82

Query: 331 DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEAL 390
           +  ++E++E   ++ KK  KKR RK  G          E + + E  + E E ++  E  
Sbjct: 83  EKQRKERREKERRKRKKEKKKRERKQRGR--------RERKKKKERKERERENKQRRERK 134

Query: 391 KEKEKPKEEEWEKPKD 406
           ++K + K+   E+ ++
Sbjct: 135 RKKRRKKKRRKERKRE 150



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 13/93 (13%)

Query: 3   DSDDEYDRRRRDKFRRERSDYDRSRE--------RDERRRGDDWNDREWDRGRERRSRGE 54
           +S+ + +RR R+K +RER + +R RE        R +R RG +   +  +R ++R+ R E
Sbjct: 33  ESERKKERREREKRKRER-EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91

Query: 55  ----YRDYDRNRRERFSPPRHELSPPQKRMRRD 83
                R  ++ +RER    R E    ++R  R+
Sbjct: 92  KERRKRKKEKKKRERKQRGRRERKKKKERKERE 124



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 13/97 (13%)

Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372
           K      S   K ++      +E +KE   +  KK  KKR ++  G              
Sbjct: 27  KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG-------------K 73

Query: 373 ESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAG 409
           E E  + E EK+  E   KE+ K K+E+ ++ +   G
Sbjct: 74  ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 25/105 (23%), Positives = 52/105 (49%), Gaps = 8/105 (7%)

Query: 302 TNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDS 361
           T  + E+K++ ++ E      +K +K E  G KE+KK    ++ ++  K+R RK      
Sbjct: 30  TQRESERKKERREREKRKREREKERKRER-GKKEKKK----RKKRERGKERERKRK---E 81

Query: 362 FDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
            ++      E E    + E++K E ++  + + K K+E  E+ ++
Sbjct: 82  REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 9   DRRRRDKFRRERSDYDRSRE--RDERRRGDDWNDRE---WDRGRERRSRGEYRDYDRNRR 63
           +R R +K RRER    R ++  R ER+R  +   RE     R +E R +   R+    ++
Sbjct: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181

Query: 64  ERFSPPRHELSPPQKRMRRDWDEHSSD 90
           ER    R E    +K+ RR   E   D
Sbjct: 182 ERERKERRERKKERKKERRKKKERKKD 208



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 4/77 (5%)

Query: 10  RRRRDKFR-RERSDYDRSRERDERRRGDDWNDREWDRGRERRSRG---EYRDYDRNRRER 65
           R++R++ + RER   +R ++R ERR  +    ++  + RER+ RG     +  +R  RER
Sbjct: 66  RKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125

Query: 66  FSPPRHELSPPQKRMRR 82
            +  R E    ++R ++
Sbjct: 126 ENKQRRERKRKKRRKKK 142



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 19/76 (25%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 7   EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERF 66
           E  R+ R+K R+ER + +R + + E+++     +R+    RER+ + E ++ +R  ++R 
Sbjct: 76  ERKRKEREKQRKERREKERRKRKKEKKK----RERKQRGRRERKKKKERKERERENKQRR 131

Query: 67  SPPRHELSPPQKRMRR 82
              R +    ++R  R
Sbjct: 132 ERKRKKRRKKKRRKER 147



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 1/74 (1%)

Query: 10  RRRRDKFRRERSDYDRSRERDERRRGDDWNDRE-WDRGRERRSRGEYRDYDRNRRERFSP 68
           + RR+K RR+R    + RER +R R +    +E  +R RE + R E +   R +++R   
Sbjct: 87  KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146

Query: 69  PRHELSPPQKRMRR 82
            + E    ++  +R
Sbjct: 147 RKREKERGKRERKR 160



 Score = 33.9 bits (76), Expect = 0.67
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 3   DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDY---- 58
           + + E  R R  K +++R   +R +ER ER+R +    R+  R +ERR R + +      
Sbjct: 49  EREKERKRERGKKEKKKRKKRERGKER-ERKRKEREKQRKERREKERRKRKKEKKKRERK 107

Query: 59  DRNRRERFSPPRHELSPPQKRMRRD 83
            R RRER      +    + + RR+
Sbjct: 108 QRGRRERKKKKERKERERENKQRRE 132



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 7/84 (8%)

Query: 5   DDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGE-------YRD 57
           + E  +R+++K +RER    R   + ++ R +   + +  R R+R+ R +        R+
Sbjct: 91  EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150

Query: 58  YDRNRRERFSPPRHELSPPQKRMR 81
            +R +RER    R +    +KR R
Sbjct: 151 KERGKRERKRKKRKKEEREKKRER 174



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 7   EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
           E  R++R K  RE+      +ER + R   +  +R+ +R +ERR + E R  DR
Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE-RKKDR 209



 Score = 30.0 bits (66), Expect = 9.7
 Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 10  RRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPP 69
           +  R+K +RER+  +R +ER+ + R +   +R+ +R R+++ R + R  DR    +   P
Sbjct: 165 KEEREK-KRERNRKERKKERERKERRERKKERKKER-RKKKERKKDRKTDRQTDSQVFRP 222

Query: 70  RHE 72
             E
Sbjct: 223 LRE 225


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 41/148 (27%), Positives = 71/148 (47%), Gaps = 23/148 (15%)

Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKT 325
           + L + EE+       E  K  E          +++   K EKK+ G+ + + SS+ D +
Sbjct: 46  KALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS 105

Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
             S       + +++ +K+ K+  KK+NR H   +S    S+SE+ES+S           
Sbjct: 106 SSS------SDSEDEDKKQGKRRKKKKNRSHKSSES----SMSETESDS----------- 144

Query: 386 AEEALKEKEKPKEEEWEKPKDAAGLECK 413
            +++LK+K+K K+   EK KD  GL  K
Sbjct: 145 -KDSLKKKKKSKDGT-EKEKDIKGLSKK 170



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 19/167 (11%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE----------RKTNDK 305
           K+  G+E+  +  +++++E++       S      + +   D E          +K  ++
Sbjct: 69  KLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNR 128

Query: 306 DEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEG 365
             K  +   +E +S + D  KK +   D  EK    EK+ K  SKKR + +S D      
Sbjct: 129 SHKSSESSMSETESDSKDSLKKKKKSKDGTEK----EKDIKGLSKKR-KMYSEDKPLSSE 183

Query: 366 SVSES----ESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAA 408
           S+SES    E  ++  ++ EE+E+A E  K+K+K K+   +K K AA
Sbjct: 184 SLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 230


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 41/148 (27%), Positives = 71/148 (47%), Gaps = 23/148 (15%)

Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKT 325
           + L + EE+       E  K  E          +++   K EKK+ G+ + + SS+ D +
Sbjct: 56  KALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS 115

Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
             S       + +++ +K+ K+  KK+NR H   +S    S+SE+ES+S           
Sbjct: 116 SSS------SDSEDEDKKQGKRRKKKKNRSHKSSES----SMSETESDS----------- 154

Query: 386 AEEALKEKEKPKEEEWEKPKDAAGLECK 413
            +++LK+K+K K+   EK KD  GL  K
Sbjct: 155 -KDSLKKKKKSKDGT-EKEKDIKGLSKK 180



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 19/167 (11%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE----------RKTNDK 305
           K+  G+E+  +  +++++E++       S      + +   D E          +K  ++
Sbjct: 79  KLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNR 138

Query: 306 DEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEG 365
             K  +   +E +S + D  KK +   D  EK    EK+ K  SKKR + +S D      
Sbjct: 139 SHKSSESSMSETESDSKDSLKKKKKSKDGTEK----EKDIKGLSKKR-KMYSEDKPLSSE 193

Query: 366 SVSES----ESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAA 408
           S+SES    E  ++  ++ EE+E+A E  K+K+K K+   +K K AA
Sbjct: 194 SLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 240


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 42/168 (25%), Positives = 87/168 (51%), Gaps = 11/168 (6%)

Query: 248 KMLDAAVIKMEGGTENDLRILEQEEEEEQAG-KPGEPSKKEEGRAGAGLGDGERKTNDKD 306
           K L+ +  K+  G E+  +  E++++ ++   +    S   +  + +   + E K   K 
Sbjct: 71  KELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKR 130

Query: 307 EKKEDGK--QAENDSSNDDKTKKSEGDGDKEEKKEDSEKE--AKKSSKKRNRKHSGDDSF 362
            KK+  +  ++   S+++ +++  E    K++ K+++EKE   +  SKKR + +  D   
Sbjct: 131 RKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPL 190

Query: 363 DEGSVSESESESESGQAE-----EEKEEAEEALKEKEKPKEEEWEKPK 405
              S SES+ E E  QA+     EE+E+A+E +K+K+K + ++  K K
Sbjct: 191 SSESSSESDYE-EDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKK 237



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 41/148 (27%), Positives = 63/148 (42%), Gaps = 24/148 (16%)

Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKT 325
           + L + EE+       E  K  E          +++   K  KK+  + + + SS+D  +
Sbjct: 56  KALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSS 115

Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
             S           DSE E KK  K+R +K +      + S  ESESES           
Sbjct: 116 SSS-----------DSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESES----------- 153

Query: 386 AEEALKEKEKPKEEEWEKPKDAAGLECK 413
            +E++K+K+K K+E  EK KD   L  K
Sbjct: 154 -KESVKKKKKSKDET-EKEKDVRSLSKK 179



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 6/104 (5%)

Query: 269 EQEEEEEQAGKPGEPSKKEEGRAG--AGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326
           E E E +++ K  + SK E  +      L    +K+   D+       +E+D   D + K
Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207

Query: 327 KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES 370
           K      + E++E ++++ KK  KK+++KHS       GS  +S
Sbjct: 208 KKR----RCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247


>gi|4557509 cylicin 2 [Homo sapiens]
          Length = 348

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 42/140 (30%), Positives = 72/140 (51%), Gaps = 13/140 (9%)

Query: 258 EGGTENDLRILEQEEE-------EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310
           +GGTE D +  +++ +       E QA K  E  K E+G+  A  GD E K   KD K+ 
Sbjct: 210 KGGTEKDSKKGKKDSKKGKDSAIELQAVKADE-KKDEDGKKDANKGD-ESKDAKKDAKEI 267

Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD--EGSVS 368
             K+ + D      T     D  K+E K+D+ K+AKK +KK   K S D   D  + +  
Sbjct: 268 --KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKK 325

Query: 369 ESESESESGQAEEEKEEAEE 388
           +++ +++    ++EK++A++
Sbjct: 326 DAKKDAKKNAKKDEKKDAKK 345



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 44/150 (29%), Positives = 78/150 (52%), Gaps = 18/150 (12%)

Query: 269 EQEEEEEQAGKPGEPSKKE--EGRAGAGLGDGERKTNDKDEKK--EDGKQAENDSSNDDK 324
           E E+E+  A K  +  KK+  +G+  A   +GE+   +KD KK  +D K+ ++ +     
Sbjct: 177 ESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQA 236

Query: 325 TK---KSEGDGDKEEKKEDSEKEAKKSSK--KRNRKHSGDDSFDEGSVSESESESESGQA 379
            K   K + DG K+  K D  K+AKK +K  K+ +K       D+   S ++S+S+    
Sbjct: 237 VKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKK-------DKKKPSSTDSDSKDDVK 289

Query: 380 EEEKEEAEEALKE--KEKPKEEEWEKPKDA 407
           +E K++A +  K+  K+  ++E  +  KDA
Sbjct: 290 KESKKDATKDAKKVAKKDTEKESADSKKDA 319



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 38/144 (26%), Positives = 71/144 (49%), Gaps = 8/144 (5%)

Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKK 327
           +E+ +EE+   K  + SKK +  A  G        ++K   K+D K+ + DS N  K   
Sbjct: 147 IEKGKEEKLDAK--KDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDS-NKGKDSA 203

Query: 328 SEGDGDKEEKKEDSEKEAKKSSKKRN-----RKHSGDDSFDEGSVSESESESESGQAEEE 382
           +E +G+K   ++DS+K  K S K ++     +    D+  DE    ++    ES  A+++
Sbjct: 204 TESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD 263

Query: 383 KEEAEEALKEKEKPKEEEWEKPKD 406
            +E ++  K+K+KP   + +   D
Sbjct: 264 AKEIKKGKKDKKKPSSTDSDSKDD 287



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 14/141 (9%)

Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKK----EDGKQAENDSSN 321
           R +E + +  + GK GE    ++    +   + E K   KD KK    E GK+ + D+  
Sbjct: 103 RTVEVDSKAAEIGKKGEDKTTQKDTTDS---ESELKQGKKDSKKGKDIEKGKEEKLDAKK 159

Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
           D  +KK + D +K +      ++ K  +KK N+K   D   ++G  S +ESE E G  E+
Sbjct: 160 D--SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDS--NKGKDSATESEGEKGGTEK 215

Query: 382 EKEEAEEALKEKEKPKEEEWE 402
           + ++ +   K+ +K K+   E
Sbjct: 216 DSKKGK---KDSKKGKDSAIE 233



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 37/148 (25%), Positives = 77/148 (52%), Gaps = 9/148 (6%)

Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGA----GLGDGERKTNDKDEKKEDGKQAENDSSND- 322
           L+Q +++ + GK  E  K+E+  A      G  D E+  +   E +++   A+ D+  D 
Sbjct: 134 LKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDK 193

Query: 323 -DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
            D  K  +   + E +K  +EK++KK   K++ K   D + +  +V   E + E G+ + 
Sbjct: 194 KDSNKGKDSATESEGEKGGTEKDSKKG--KKDSKKGKDSAIELQAVKADEKKDEDGKKDA 251

Query: 382 EK-EEAEEALKEKEKPKEEEWEKPKDAA 408
            K +E+++A K+ ++ K+ + +K K ++
Sbjct: 252 NKGDESKDAKKDAKEIKKGKKDKKKPSS 279



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 7/82 (8%)

Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS------SNDDKTKKSEGDG 332
           K G+  KK+     +   D  +K + KD  K+  K A+ D+      S  D  K ++ D 
Sbjct: 268 KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDA 327

Query: 333 DKEEKKEDSEKEAKKSSKKRNR 354
            K+ KK +++K+ KK +KK+ +
Sbjct: 328 KKDAKK-NAKKDEKKDAKKKGK 348


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 12/110 (10%)

Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTK-KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS 357
           E K   +D+K+E  K  +  +  +DKT  K E    KEE K++ +KE KK  KK  +K  
Sbjct: 641 ETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEV 700

Query: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDA 407
                      + E+  +  + E +KEE +E  KE+++PK+E  + PKDA
Sbjct: 701 -----------KKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDA 739



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 43/146 (29%), Positives = 67/146 (45%), Gaps = 7/146 (4%)

Query: 261  TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320
            TE +    +  EE E   K G    ++    GAG  +   +T D +EK E  +  E +  
Sbjct: 899  TEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESS-ETGDYEEKAETEEAEEPEED 957

Query: 321  NDDKTKKSEGDGDKEEKKEDSEKEAKKSSK-KRNRKHSGDDSFDEGSVSESESESESGQA 379
             ++    S       E +E ++ EA    + KR    SGDD  +E    + +   E G+A
Sbjct: 958  GEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEE----DMDEAIEKGEA 1013

Query: 380  EEEKEEAEEALKEKEKPKEEEWEKPK 405
            E+ +EEA+E  K  E  +EEE+E  K
Sbjct: 1014 EQSEEEADEEDK-AEDAREEEYEPEK 1038



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 11/142 (7%)

Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKK 327
           ++ E+++E+  KP +   K+E +      +  +K   K E K++ K+ E      +  K+
Sbjct: 644 VKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKE 703

Query: 328 SEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAE 387
           +     K+E K++ +KE KK  K+  +         E      +++  S    E K+ A 
Sbjct: 704 TPPKEVKKEVKKEEKKEVKKEEKEPKK---------EIKKLPKDAKKSSTPLSEAKKPA- 753

Query: 388 EALKEKEKPKEEEWEKPKDAAG 409
            ALK K   KEE  +K   AAG
Sbjct: 754 -ALKPKVPKKEESVKKDSVAAG 774



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 6/119 (5%)

Query: 305 KDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDE 364
           K E K    + E  S  +    K+E    +++  +   K AK+ + K+  K   +D  +E
Sbjct: 595 KTETKPSVTEKEVPSKEEPSPVKAEVA--EKQATDVKPKAAKEKTVKKETKVKPEDKKEE 652

Query: 365 GSVSESE---SESESGQAEEEKEEAEEALKE-KEKPKEEEWEKPKDAAGLECKPRPLHK 419
               + E    E ++   +EEK + EE  KE K++ K+EE ++PK     E  P+ + K
Sbjct: 653 KEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKK 711



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 320 SNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS-VSESESESESGQ 378
           S D+    +EG+G+ E+  E+ E   K+      +       F+E S   + E ++E+ +
Sbjct: 891 SPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEE 950

Query: 379 AEEEKEEAEEAL---KEKEKPKEEE 400
           AEE +E+ EE +     K  P E+E
Sbjct: 951 AEEPEEDGEEHVCVSASKHSPTEDE 975



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 35/142 (24%), Positives = 60/142 (42%), Gaps = 18/142 (12%)

Query: 273  EEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK--QAENDSSNDDKTKKSEG 330
            E+E++ K    +   E R     GD +R   D DE  E G+  Q+E ++  +DK + +  
Sbjct: 973  EDEESAKAEADAYIREKRESVASGD-DRAEEDMDEAIEKGEAEQSEEEADEEDKAEDARE 1031

Query: 331  DGDKEEKKE---------DSEKEAKKSSKKRN-----RKHSGDDSFDEGSVSESESESES 376
            +  + EK E         D   EA  + ++        K  G  S      S    E+  
Sbjct: 1032 EEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLP 1091

Query: 377  GQAEEEKEEAEEALKEKEKPKE 398
            G +E E   ++E  +E ++P+E
Sbjct: 1092 GGSESEATASDEENRE-DQPEE 1112



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 8/118 (6%)

Query: 283 PSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE 342
           P+K+ E      +   E  T D +E K +    E D + D K +  E   D+E+ KE   
Sbjct: 819 PAKELEAERSL-MSSPEDLTKDFEELKAE----EVDVTKDIKPQL-ELIEDEEKLKETEP 872

Query: 343 KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAE-EALKEKEKPKEE 399
            EA    K+R       +S DEG ++ +E E E  Q  EE E  E + + + EK ++E
Sbjct: 873 VEAYVIQKEREVTKGPAESPDEG-ITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDE 929


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 45/164 (27%), Positives = 77/164 (46%), Gaps = 8/164 (4%)

Query: 251  DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310
            + A  + EG T+ +  ++E +E EE+A    E  +  E        +GE +   +D    
Sbjct: 1944 EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDV--- 2000

Query: 311  DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES 370
            +  +AE +    ++  + E DG + + K  SE E  +  +   +K  GD   +   V   
Sbjct: 2001 EAPEAEGEMQEAEEEAQPESDGVEAQPK--SEGEEAQEVEGETQKTEGDAQPESDGVEAP 2058

Query: 371  ESESESGQAEEEKEEAE-EALKEKE--KPKEEEWEKPKDAAGLE 411
            E+E E+ +AE E +EAE EA  E E    +E E E   ++ G+E
Sbjct: 2059 EAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVE 2102



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 40/165 (24%), Positives = 83/165 (50%), Gaps = 12/165 (7%)

Query: 256  KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK-Q 314
            ++EG T+      + E +  +A +  E +++ EG      G+   ++ D D ++ +G+ Q
Sbjct: 2036 EVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQ 2095

Query: 315  AENDSSN----DDKTKKSEG----DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS 366
             E++       + + +K+EG    + + E + E    EA ++  +   +  G ++ D  +
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQD--A 2153

Query: 367  VSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLE 411
              E++ ESE  +A+E +EEA+  L+  E P E E E   ++ G+E
Sbjct: 2154 EGEAQPESEGIEAQEAEEEAQPELEGVEAP-EAEGEAQPESEGIE 2197



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 8/142 (5%)

Query: 274  EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGD 333
            +E+ GK    +   E  AG+ LG+ E++     E+ E G Q      N      + GD D
Sbjct: 1770 QEREGK----THNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD 1825

Query: 334  KEEKKEDSEKEAKKSSKKRNRKHSGDDSFD-EGSVSESESESESGQAEEEKEEAE-EALK 391
              +       EA ++  +   +  G ++ + EG   E+E E++    + E  EAE EA  
Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP 1885

Query: 392  EKE--KPKEEEWEKPKDAAGLE 411
            E E  +  E EWE   ++ G E
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAE 1907



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 38/158 (24%), Positives = 71/158 (44%), Gaps = 9/158 (5%)

Query: 262  ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA----EN 317
            E +++  E+E + E  G   +P  K EG     +    +KT    + + DG +A    E 
Sbjct: 2006 EGEMQEAEEEAQPESDGVEAQP--KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEE 2063

Query: 318  DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES-ESESES 376
                + + +++EG+   E +  D++ EA+  ++  +      ++  E   +E  E+    
Sbjct: 2064 AQEAEGEVQEAEGEAHPESEDVDAQ-EAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETE 2122

Query: 377  GQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKP 414
            G+A+ E E  E    E E   E E  + +DA G E +P
Sbjct: 2123 GEAQPESEGIEAPEAEGEAQPESEGVEAQDAEG-EAQP 2159



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 36/172 (20%), Positives = 78/172 (45%), Gaps = 6/172 (3%)

Query: 238  LDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD 297
            ++  +A+   +  +  V + EG    +   ++ +E E +A    E  +  E    A   +
Sbjct: 2055 VEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE 2114

Query: 298  GERKTNDKDEKKEDGKQAENDSSNDDKTKKSEG----DGDKEEKKEDSEKEAKKSSKKRN 353
            G      + E + + +  E   +  +   +SEG    D + E + E    EA+++ ++  
Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQ 2174

Query: 354  RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPK 405
             +  G ++ +  +  E++ ESE  +A E + EA+  L+  E P+ EE  +P+
Sbjct: 2175 PELEGVEAPE--AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE 2224



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 14/169 (8%)

Query: 251  DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD---GERKTN-DKD 306
            DA   + EG T N       E  E +    G   + E G  G+G  D   GE     D+D
Sbjct: 1766 DAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD 1825

Query: 307  EKKEDGKQA-ENDSSNDDKTKKSEG------DGDKEEKKEDSEKEAKKSSKKRNRKHSGD 359
              + DG +  E   +  +   +SEG      +GD +E + +++ E++          +  
Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP 1885

Query: 360  DSFDEGSVS---ESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPK 405
            +S D  +     E + ESE  +A E ++EA+   +  E  + E  ++P+
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPE 1934



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 41/187 (21%), Positives = 85/187 (45%), Gaps = 18/187 (9%)

Query: 239  DIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-----GA 293
            D++  +A  +M +A   + E   E+D    + + E E+A +    ++K EG A     G 
Sbjct: 1999 DVEAPEAEGEMQEA---EEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGV 2055

Query: 294  GLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEE---KKEDSEKEAKKSSK 350
               + E +  + + + ++ +   +  S D   +++EG+   E    +  ++E EA+K+  
Sbjct: 2056 EAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEG 2115

Query: 351  KRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE------KPKEEEWEKP 404
                +  G+   +   +   E+E E+ Q E E  EA++A  E +      + +E E E  
Sbjct: 2116 IEAPETEGEAQPESEGIEAPEAEGEA-QPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQ 2174

Query: 405  KDAAGLE 411
             +  G+E
Sbjct: 2175 PELEGVE 2181



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 16/112 (14%)

Query: 287  EEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAK 346
            +EG  G GL   E     ++ K E+G Q E      ++TK++EG+G +EE+ +  E E  
Sbjct: 1307 KEGTEGEGLQ--EEAVQLEETKTEEGLQEEGVQL--EETKETEGEGQQEEEAQLEEIE-- 1360

Query: 347  KSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKE 398
                      +G +   E  V + E   E  +   + E  EE LKE+  P+E
Sbjct: 1361 ---------ETGGEGLQEEGV-QLEEVKEGPEGGLQGEALEEGLKEEGLPEE 1402



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 33/145 (22%), Positives = 66/145 (45%), Gaps = 11/145 (7%)

Query: 268  LEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKK 327
            +E  E E +A    E  +  E    A   +GE +   +D +  + +      S D +T +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPE 1894

Query: 328  SEGDGDKEEK---KEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESES-----GQA 379
            +E +   E +     ++EKEA+  ++      +  +   E   +E++   E+     GQ 
Sbjct: 1895 AEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQT 1954

Query: 380  EEEKE--EAEEALKEKEKPKEEEWE 402
            + E E  E++EA +E+ +P+ E+ E
Sbjct: 1955 QPESEVIESQEA-EEEAQPESEDVE 1978



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 37/163 (22%), Positives = 70/163 (42%), Gaps = 7/163 (4%)

Query: 258  EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
            E   + ++++ E +E  E  G   E  + EE +   GL +   +  +  E + +G+Q E 
Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEE 1353

Query: 318  DSSNDDKTKKSEGDGDK----EEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESE 373
                + +    EG  ++    EE KE  E   +  + +   K  G    +EGSV   E  
Sbjct: 1354 AQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLP--EEGSVHGQEL- 1410

Query: 374  SESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRP 416
            SE+   + +  + ++ ++E+E  +     +P  A G E    P
Sbjct: 1411 SEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEP 1453



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 28/129 (21%), Positives = 61/129 (47%), Gaps = 3/129 (2%)

Query: 273  EEEQAGKPGEPSKKE-EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
            E  +A K  +P  +  E     G  + E +  +  E +E  ++AE  +  + +  +S+ +
Sbjct: 1907 EAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ-E 1965

Query: 332  GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALK 391
             ++E + E  + EA +   +  ++  G+   +   V   E+E E  +AEEE +   + ++
Sbjct: 1966 AEEEAQPESEDVEALEVEVE-TQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVE 2024

Query: 392  EKEKPKEEE 400
             + K + EE
Sbjct: 2025 AQPKSEGEE 2033



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 22/149 (14%)

Query: 268  LEQEEEEEQAGKPGEPSKKEEGRAGA-GLGDGERKTNDKDEKKEDGK-QAENDSSNDDKT 325
            LE E E+E   +  E  + EE    A G    E +  +  E +E+ + ++E+  + + + 
Sbjct: 1925 LETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV 1984

Query: 326  KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE---SGQAEEE 382
            +  E +G+ + + ED E                     EG + E+E E++    G   + 
Sbjct: 1985 ETQEAEGEAQPESEDVEAPEA-----------------EGEMQEAEEEAQPESDGVEAQP 2027

Query: 383  KEEAEEALKEKEKPKEEEWEKPKDAAGLE 411
            K E EEA + + + ++ E +   ++ G+E
Sbjct: 2028 KSEGEEAQEVEGETQKTEGDAQPESDGVE 2056



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 36/189 (19%), Positives = 75/189 (39%), Gaps = 32/189 (16%)

Query: 258  EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKD----------E 307
            EG  + +   +E  E E  A +    ++ E     A   +GE +   +D          +
Sbjct: 1841 EGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQ 1900

Query: 308  KKEDGKQA-ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS 366
             + +G +A E +     +T+  E    + E + +SE    + +++  ++  G    +   
Sbjct: 1901 PESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEV 1960

Query: 367  VSESESESES--------------------GQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
            +   E+E E+                    G+A+ E E+ E    E E  + EE  +P +
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQP-E 2019

Query: 407  AAGLECKPR 415
            + G+E +P+
Sbjct: 2020 SDGVEAQPK 2028



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 10/129 (7%)

Query: 291  AGAGLGDGERKTNDKDEKKEDGKQAEN-DSSNDDKTKKSEGDG---DKEEKKEDSEKEAK 346
            A  GLG G  +    DE  EDG+ ++  +   D K  ++EGD    ++E K  +SE  A 
Sbjct: 1726 AEGGLGPGLSQGPGVDEG-EDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAG 1784

Query: 347  KSSKKRNRKHSG----DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWE 402
                +  ++  G     ++  +GS  E   + E+    ++     +  +  E P E E E
Sbjct: 1785 SELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAP-EAEGE 1843

Query: 403  KPKDAAGLE 411
               ++ G+E
Sbjct: 1844 AQPESEGVE 1852


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 53/235 (22%), Positives = 98/235 (41%), Gaps = 10/235 (4%)

Query: 175 YKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFD 234
           ++ D +R++ +   +  K+ E  R K H +E  K R+E     +  +    S  E G  D
Sbjct: 99  HRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERG-ND 157

Query: 235 NLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAG 294
            + L  D+ + + +  +          E  +R  ++E+ E++  +     +++E  A   
Sbjct: 158 GVCLFRDRLEQLERKRER---------ERKMREQQKEQREQKERERRAEERRKEREARRE 208

Query: 295 LGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNR 354
           +    R   +    K              + +   GDG K  K+E  E+    S  +   
Sbjct: 209 VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDIS 268

Query: 355 KHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAG 409
                 S  E S +ES S SE  + EEE+EE E +  E+ + +EEE E+ ++  G
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 323



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 78/401 (19%), Positives = 151/401 (37%), Gaps = 83/401 (20%)

Query: 12  RRDKFRRERSDYDRSRERD--------ERRRGDDWNDREWDRGRER---RSRGEYRDYDR 60
           R   +RRE S  DR  E D        +  R +  + R+ ++ +E+   R + + R+++R
Sbjct: 63  RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHER 122

Query: 61  NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
            +R R           Q + RR+W+          +     G  G              V
Sbjct: 123 RKRHR---------EEQDKARREWERQKRREMAREHSRRERGNDG--------------V 159

Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
            + +  +  ++ +     E  +       +  KE     ++   E EA +  + +     
Sbjct: 160 CLFRDRLEQLERKRER--ERKMREQQKEQREQKERERRAEERRKEREARREVSAH----H 213

Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
           R   +D+    K   W RS   P        + R  ++        L+        L DI
Sbjct: 214 RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD------LQDI 267

Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
             ++      +++  +   G+E +    E+EEEEE+ G   E S++EE            
Sbjct: 268 SDSERKTSSAESSSAESGSGSEEEE---EEEEEEEEEGSTSEESEEEE------------ 312

Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
                  ++E+ ++ E  S++++ +++S  +  +EE  ED E+E        N  H    
Sbjct: 313 -------EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE--------NENHLL-- 355

Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEW 401
                 V ES  + +SG++EE +EE  E   +     E ++
Sbjct: 356 -----VVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDY 391



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 16/104 (15%)

Query: 1   MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
           MGD  D +  +  D+  +E+       E+ E +R  + +DR  D  R+    GE RD+  
Sbjct: 1   MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDR--DSKRDSLEEGELRDHCM 58

Query: 61  NRRERFSPPRHE--------------LSPPQKRMRRDWDEHSSD 90
               R SP R E              + PPQ+  R++   H  D
Sbjct: 59  EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKD 102



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 21/80 (26%)

Query: 11  RRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERF---- 66
           R+R++ R+ R      RE+ ER R      R  +R +ER +R E   + R  RE +    
Sbjct: 171 RKRERERKMREQQKEQREQKERER------RAEERRKEREARREVSAHHRTMREDYSDKV 224

Query: 67  -------SPPRHELSPPQKR 79
                  SPPR    PP++R
Sbjct: 225 KASHWSRSPPR----PPRER 240



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 22/108 (20%), Positives = 42/108 (38%), Gaps = 9/108 (8%)

Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358
           E+K   + E+K + K+ +N    D K         ++  +E   ++       RN  +  
Sbjct: 19  EKKRRKEQEEKAEIKRLKNSDDRDSK---------RDSLEEGELRDHCMEITIRNSPYRR 69

Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
           +DS ++    +     +  Q    KE+      EK K K+    K K+
Sbjct: 70  EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKE 117



 Score = 30.0 bits (66), Expect = 9.7
 Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 17/100 (17%)

Query: 333 DKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSE--------------SESESESGQ 378
           +K+ +KE  EK   K  K  + + S  DS +EG + +               +S  + G+
Sbjct: 19  EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78

Query: 379 AEEE---KEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
            ++    K   + + KEK   +++E  K K  A ++ K R
Sbjct: 79  EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKER 118


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 47/187 (25%), Positives = 83/187 (44%), Gaps = 10/187 (5%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
           K +   E D    E EE++E   +  +  +    +A A     E + ++ DE  ED    
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201

Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
           E D S ++  + +   G K  K    +  AK  ++  + +   +D  D+    + + + E
Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVK--AKNVAEDEDEEEDDEDEDDDDDEDDEDDDDE 259

Query: 376 SGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT-----CSLFMRNIAP 430
             + EEE+EE EE +KE    +++E  K K  A  E K + +  T      +LF+ N+  
Sbjct: 260 DDE-EEEEEEEEEPVKEAPGKRKKEMAKQK--AAPEAKKQKVEGTEPTTAFNLFVGNLNF 316

Query: 431 NISRAEI 437
           N S  E+
Sbjct: 317 NKSAPEL 323



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 17/74 (22%), Positives = 38/74 (51%), Gaps = 1/74 (1%)

Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEK 393
           K  KKEDS++E    S++ + +   D+  DE  +  +  ++ +     E E+ E+   ++
Sbjct: 138 KNAKKEDSDEEEDDDSEE-DEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDE 196

Query: 394 EKPKEEEWEKPKDA 407
           +   +EE +  ++A
Sbjct: 197 DDDDDEEDDSEEEA 210


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 20/153 (13%)

Query: 263 NDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322
           ++LRI + E++ E +    + S +E GR          K   K    + G++ +    +D
Sbjct: 203 SELRIHDLEDDLEMSSDASDASGEEGGRVP--------KAKKKAPLAKGGRKKKKKKGSD 254

Query: 323 DKTKKSEGDGDKEEKKED-------SEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
           D+  +   DGD E ++ D       S +E  +S  K  ++  G    DE S S  ESE E
Sbjct: 255 DEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEE 314

Query: 376 SGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAA 408
               EE+KEE E    EK+ P  +E ++ KD++
Sbjct: 315 K-PPEEDKEEEE----EKKAPTPQEKKRRKDSS 342



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 46/160 (28%), Positives = 76/160 (47%), Gaps = 23/160 (14%)

Query: 263 NDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322
           N   I++Q   ++Q     E  K++ GR  A     E + +D ++  E    A + S  +
Sbjct: 172 NHFSIMQQRRLKDQDQDEDEEEKEKRGRRKAS----ELRIHDLEDDLEMSSDASDASGEE 227

Query: 323 D----KTKKSEG---DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS---ESES 372
                K KK       G K++KK+ S+ EA + S   + +    D   +GS S   E ES
Sbjct: 228 GGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPES 287

Query: 373 ESESGQAEE-------EKEEAEEALKEK--EKPKEEEWEK 403
           ++++ Q EE       + + +EE+ +EK  E+ KEEE EK
Sbjct: 288 KAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEK 327



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 7/113 (6%)

Query: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN-DDKTKKSEGDGDKEEKKEDSEKEAK 346
           EG+    + DG   + ++ E K    Q E      D+++  SE   +++  +ED E+E +
Sbjct: 267 EGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEE 326

Query: 347 KSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE 399
           K +     K    DS      SE    SE    + E   A    K+K  PK E
Sbjct: 327 KKAPTPQEKKRRKDS------SEESDSSEESDIDSEASSALFMAKKKTPPKRE 373



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 39/147 (26%), Positives = 57/147 (38%), Gaps = 30/147 (20%)

Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK--- 326
           QEE E +A  P    ++EEG  G        + +D  E+ E+ K  E D   +++ K   
Sbjct: 282 QEEPESKAKAP----QQEEGPKGVD------EQSDSSEESEEEKPPEEDKEEEEEKKAPT 331

Query: 327 ---------KSEGDGDKEEKKEDSEKEA------KKSSKKRNRKHSGDDSFDEGSVSESE 371
                     SE     EE   DSE  +      KK+  KR RK SG  S   G+     
Sbjct: 332 PQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSS--RGNSRPGT 389

Query: 372 SESESGQAEEEKEEAEEALKEKEKPKE 398
             +E G        A   L++ ++  E
Sbjct: 390 PSAEGGSTSSTLRAAASKLEQGKRVSE 416


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 39/165 (23%), Positives = 85/165 (51%), Gaps = 21/165 (12%)

Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGDGERK 301
           V+  +  V + EG   E + ++ EQE    E+EEQ G+  E  +K+E + G      E++
Sbjct: 173 VREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG------EQE 226

Query: 302 TNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDS 361
              + ++++ G+Q E     +++ +K E    K+E++   ++E  +  +++  K      
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK---- 282

Query: 362 FDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
                  ++E E ++G+ EE+  E EE ++E+E+   E+ E+ ++
Sbjct: 283 ------EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 39/170 (22%), Positives = 84/170 (49%), Gaps = 10/170 (5%)

Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGD-GER 300
           V+  +  V + EG   E + ++ EQE    E+E Q  +     +++EG+ G   G  GE+
Sbjct: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204

Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
           +    +++++  KQ E     +++ +K E    ++E++   ++E  +  +++ RK     
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264

Query: 361 SFDEGSVSESESE----SESGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
              E  + E E +     E  + EE+  E EE ++E+E+   E+ E+ ++
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 35/150 (23%), Positives = 73/150 (48%), Gaps = 24/150 (16%)

Query: 262 ENDLRILEQEEE----EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
           E + ++ EQEE+    EEQ G+  E  +K+E + G             +++++  KQ E 
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG-------------EQEEQVQKQEEQ 249

Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
               +++ +K E   ++  ++E+  +E ++   K+  +   ++   E      E E +  
Sbjct: 250 VQKQEEQMRKQE---EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306

Query: 378 QAEEEKEEAEEALKEKE----KPKEEEWEK 403
           + EE+  E EE ++E+E    K +E+ WE+
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 34/161 (21%), Positives = 78/161 (48%), Gaps = 20/161 (12%)

Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKED---- 311
           +M    E  L+  EQ E+EEQ G+  E  +++E +    + + E +  +++E+  +    
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ----MREQEEQMREQEEQMREQEEQ 325

Query: 312 -GKQAEND--------SSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSF 362
            GKQ E             +   K+ E  G++EE+ +  E++ +K  ++  ++   ++  
Sbjct: 326 MGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ---EEQM 382

Query: 363 DEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
            +      + E + G+ +E+  E +E ++E+E+   E+ E+
Sbjct: 383 RKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQ 423



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 33/147 (22%), Positives = 73/147 (49%), Gaps = 5/147 (3%)

Query: 259 GGTENDLRILEQE--EEEEQAGKPGEPSKKEEGRAGAGLGD-GERKTNDKDEKKEDGKQA 315
           G  E  +R  E++  E+EEQ  +  E  +++E + G       E+K    ++K++  KQ 
Sbjct: 292 GEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351

Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
           E     +++ +K E    K+E++   ++E  +  +++ RK   ++   E      E + +
Sbjct: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ--EEQMGEQKEQMGEQKEQ 409

Query: 376 SGQAEEEKEEAEEALKEKEKPKEEEWE 402
             + EE+  E +E ++++E+   E+ E
Sbjct: 410 MREQEEQMGEQKEQMRKQEEHMGEQKE 436



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 32/140 (22%), Positives = 66/140 (47%), Gaps = 18/140 (12%)

Query: 269 EQEEE----EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS-SNDD 323
           EQEE+    EEQ G+  E  +K+E +         ++     E++E  ++ E       +
Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283

Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
           +T++ E  G++EE+  + E++ ++           ++   E      E E + G+ EE+ 
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQ----------EEQMREQEEQMREQEEQMGKQEEQM 333

Query: 384 EEAEEALKEKEKPKEEEWEK 403
            E +E + E+   KE+ W++
Sbjct: 334 WEQKEQMWEQ---KEQMWKQ 350



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 28/141 (19%), Positives = 67/141 (47%), Gaps = 2/141 (1%)

Query: 262 ENDLRILEQE--EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319
           E  +R  E++  E+EEQ  +  E   K++ +       GE++   ++++++  +Q E   
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR 313

Query: 320 SNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQA 379
             +++ ++ E    K+E++   +KE     K++  K        E  + + E +    + 
Sbjct: 314 EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373

Query: 380 EEEKEEAEEALKEKEKPKEEE 400
           +  K+E +   +E++  K+EE
Sbjct: 374 QMRKQEEQMRKQEEQMRKQEE 394



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 33/165 (20%), Positives = 80/165 (48%), Gaps = 12/165 (7%)

Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGDGERK 301
           V+  +  V + EG   E + ++ EQE    E+E Q  +     +++EG+      +G+ +
Sbjct: 75  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVR 132

Query: 302 TNDKDEKKEDGKQAENDSS---NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358
             +   ++++G+  E +      + + ++ EG   ++E +   ++   +  + + R+  G
Sbjct: 133 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 192

Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
                EG +   E E + G+ EE+ ++ EE + E+E+   ++ E+
Sbjct: 193 QMGEQEGQMG--EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 35/166 (21%), Positives = 78/166 (46%), Gaps = 12/166 (7%)

Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGD-GER 300
           V+  +  V + EG   E + ++ EQE    E+E Q  +     +++EG+     G   E+
Sbjct: 124 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183

Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
           +   ++++ + G+Q       +++  + E    K+E++   ++E  +  +++  +     
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243

Query: 361 SFDEGSVSESE------SESESGQAEEEKEEAEEALKEKEKPKEEE 400
              E  V + E       E    Q E+ +E+ E+ LK+KE+ ++EE
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEE 289



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 31/156 (19%), Positives = 73/156 (46%), Gaps = 24/156 (15%)

Query: 269 EQEEE----EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDK 324
           EQEE+    EEQ  K  E  +K+E +        E++   ++++++  KQ E     +  
Sbjct: 238 EQEEQVQKQEEQVQKQEEQMRKQEEQMR------EQEEQMREQEEQMLKQKEQTEQEEQT 291

Query: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE-----------SE 373
            ++ E   ++EE+  + E++ ++  ++   +       +E    + E            E
Sbjct: 292 GEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351

Query: 374 SESGQAEEEKEEAEEALKEKE---KPKEEEWEKPKD 406
            + G+ EE+ ++ EE ++++E   + +EE+  K ++
Sbjct: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 31/170 (18%), Positives = 80/170 (47%), Gaps = 15/170 (8%)

Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGDGERK 301
           V+  +  V + EG   E + ++ EQE    E+E Q  +     +++EG+      +G+ +
Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVR 167

Query: 302 TNDKDEKKEDGKQAENDSS---NDDKTKKSEGDGDKE-----EKKEDSEKEAKKSSKKRN 353
             +   ++++G+  E +      + +  + EG   ++     E++E  +K+ ++  ++  
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227

Query: 354 RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
           +    ++   E      + E +  + EE+  + EE ++E+E+   E+ E+
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQ 277



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 31/163 (19%), Positives = 80/163 (49%), Gaps = 13/163 (7%)

Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGDGERK 301
           V+  +  V + EG   E + ++ EQE    E+E Q  +     +++EG+      +G+ +
Sbjct: 103 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVR 160

Query: 302 TNDKDEKKEDGKQAENDSS---NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358
             +   ++++G+  E +      + + ++ EG   ++E +   ++E     +++ +K   
Sbjct: 161 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ-- 218

Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEE-ALKEKEKPKEEE 400
           ++   E      + E + G+ EE+ ++ EE   K++E+ +++E
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 29/156 (18%), Positives = 70/156 (44%), Gaps = 9/156 (5%)

Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS- 320
           + +L+++E E+ E Q        K E  +      +G+ +  +   ++++G+  E +   
Sbjct: 17  QEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ-EGQVREQEGQVREQEGQVREQEGQV 75

Query: 321 --NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESE--SES 376
              + + ++ EG   ++E +   ++   +  + + R+  G     EG V E E +   + 
Sbjct: 76  REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 135

Query: 377 GQAEEEK---EEAEEALKEKEKPKEEEWEKPKDAAG 409
           GQ  E++    E E  ++E+E    E+  + ++  G
Sbjct: 136 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 171


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,142,223
Number of Sequences: 37866
Number of extensions: 2647740
Number of successful extensions: 45016
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 788
Number of HSP's successfully gapped in prelim test: 1173
Number of HSP's that attempted gapping in prelim test: 15558
Number of HSP's gapped (non-prelim): 15779
length of query: 872
length of database: 18,247,518
effective HSP length: 111
effective length of query: 761
effective length of database: 14,044,392
effective search space: 10687782312
effective search space used: 10687782312
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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