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Search of human proteins with 192807309
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens] 664 0.0
gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens] 664 0.0
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 173 2e-43
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 71 1e-12
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 71 1e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 70 2e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 69 4e-12
gi|148746195 trichohyalin [Homo sapiens] 69 4e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 67 3e-11
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 66 4e-11
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 66 4e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 65 8e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 2e-10
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 62 5e-10
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 62 5e-10
gi|55770834 centromere protein F [Homo sapiens] 62 5e-10
gi|33946313 ninein isoform 4 [Homo sapiens] 62 5e-10
gi|33946321 ninein isoform 5 [Homo sapiens] 62 5e-10
gi|148536871 ninein isoform 1 [Homo sapiens] 62 5e-10
gi|148536869 ninein isoform 2 [Homo sapiens] 62 5e-10
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 62 9e-10
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 62 9e-10
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 62 9e-10
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 61 2e-09
gi|187608545 centrosomal protein 55kDa [Homo sapiens] 60 3e-09
gi|187608537 centrosomal protein 55kDa [Homo sapiens] 60 3e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 60 3e-09
gi|4503593 epidermal growth factor receptor pathway substrate 15... 59 6e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 59 6e-09
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 59 6e-09
>gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens]
Length = 325
Score = 664 bits (1712), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQ 60
MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQ
Sbjct: 1 MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQ 60
Query: 61 FRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
FRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE
Sbjct: 61 FRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
Query: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC 180
EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC
Sbjct: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC 180
Query: 181 LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLN 240
LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLN
Sbjct: 181 LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLN 240
Query: 241 RLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQW 300
RLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQW
Sbjct: 241 RLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQW 300
Query: 301 YALDQLPPDVQHKANGLSSVKKVHP 325
YALDQLPPDVQHKANGLSSVKKVHP
Sbjct: 301 YALDQLPPDVQHKANGLSSVKKVHP 325
>gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens]
Length = 325
Score = 664 bits (1712), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQ 60
MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQ
Sbjct: 1 MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQ 60
Query: 61 FRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
FRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE
Sbjct: 61 FRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
Query: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC 180
EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC
Sbjct: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC 180
Query: 181 LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLN 240
LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLN
Sbjct: 181 LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLN 240
Query: 241 RLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQW 300
RLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQW
Sbjct: 241 RLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQW 300
Query: 301 YALDQLPPDVQHKANGLSSVKKVHP 325
YALDQLPPDVQHKANGLSSVKKVHP
Sbjct: 301 YALDQLPPDVQHKANGLSSVKKVHP 325
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 173 bits (439), Expect = 2e-43
Identities = 98/250 (39%), Positives = 164/250 (65%), Gaps = 12/250 (4%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKD 92
+ + E+K++ LE+QR ELLEVN+QWDQ FRSMK+ YE+K+ EL+ KL ++ ++ E +
Sbjct: 296 LGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE 355
Query: 93 PHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEK 152
++ +QR+ DR+ L + +++ EE +KE+L E EL+++ K L+ + + +++
Sbjct: 356 ------REQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQR 409
Query: 153 EHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVE-----FCHEEMRTEMEVLKQQVQIY 207
E+ E EI+RLNKAL++AL+I+ S E +E+ T+ E+LKQQV+I+
Sbjct: 410 EYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIF 469
Query: 208 EEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMYCPP 267
EEDF++ERSDRER+N+EKEEL++ E Q+Q+ N+Q+KA + ++EK + L+Q
Sbjct: 470 EEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFK-DEEKAREALRQQKRKA 528
Query: 268 CNCGLVFHLQ 277
G +H++
Sbjct: 529 KASGERYHVE 538
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 71.2 bits (173), Expect = 1e-12
Identities = 57/256 (22%), Positives = 131/256 (51%), Gaps = 16/256 (6%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSM---KELYERK 71
E EH S R+ S E +++ +EK+ K L E ++ + + K +++
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKE 616
Query: 72 VAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEEL 131
+ K K + AE E + H +++++ ++ +T ++++ E+E L E
Sbjct: 617 LEHYKEKGERAEEL----ENELHHLEKENELLQKKITNLKITCEKIEALEQENSELEREN 672
Query: 132 HELKEENKLLKGKN-TLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCH 190
+LK+ K L + EKE+ + + + L + ++ ++KC+ ++ ++++ +
Sbjct: 673 RKLKKTLDSFKNLTFQLESLEKENSQLDEENL-ELRRNVESLKCA----SMKMAQLQLEN 727
Query: 191 EEMRTEMEVLKQQVQIYEEDFKK-ERSD--RERLNQEKEELQQINETSQSQLNRLNSQIK 247
+E+ +E E LK+ +++ + FKK ER + + L+ E + LQ+ E S ++ +L S+++
Sbjct: 728 KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Query: 248 ACQMEKEKLEKQLKQM 263
+ME + L+K L+++
Sbjct: 788 DLEMENQTLQKNLEEL 803
Score = 52.8 bits (125), Expect = 4e-07
Identities = 64/273 (23%), Positives = 110/273 (40%), Gaps = 27/273 (9%)
Query: 10 RMIAAESSTEHK-----ECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSM 64
R++ E ST+ E ST K + E+KI LE + +E NQQ Q+ +++
Sbjct: 941 RLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTV 1000
Query: 65 KELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEK 124
K+ YE LK + D ER + + + + + +E R+ +DRL E+
Sbjct: 1001 KKNYE----ALKQRQD-EERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN 1055
Query: 125 ERLNEELHELKEENKLLKGKNTLANKE---KEHYECEIKRLNKALQDALNIKCSFSEDCL 181
L E LK + K L+ +N + + ++ N LQ N K L
Sbjct: 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ-TQNAKLQVENSTL 1114
Query: 182 RKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERL------NQEKEELQQINETS 235
++ ++ + + ++ E KER D + L + EK EL + S
Sbjct: 1115 NSQSTSLMNQ--NAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQAS 1172
Query: 236 Q-----SQLNRLNSQIKACQMEKEKLEKQLKQM 263
+ S+ L S K ++E LE + Q+
Sbjct: 1173 EYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1205
Score = 48.9 bits (115), Expect = 6e-06
Identities = 53/263 (20%), Positives = 110/263 (41%), Gaps = 36/263 (13%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAE 74
E+S +E E + K+ L+ + KEL +Q + +K + +K
Sbjct: 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF-KKTER 753
Query: 75 LKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHEL 134
L+ + +K +K + + + ++ LQ+ +E + ++ L +L
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Query: 135 KEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMR 194
++ENK L+ + + K+K+ E E KRL + + + L ++ V+ +
Sbjct: 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQ--------QAEIKDTTLEENNVKI--GNLE 863
Query: 195 TEMEVLKQQVQIYEE------DFKKERSD---------------RERLNQEKEELQQINE 233
E + L +++ IY+E + +KE + RE L EK + QQ+N
Sbjct: 864 KENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMN- 922
Query: 234 TSQSQLNRLNSQIKACQMEKEKL 256
+ L +L +++ + KE+L
Sbjct: 923 ---NDLEKLTHELEKIGLNKERL 942
Score = 41.6 bits (96), Expect = 0.001
Identities = 51/262 (19%), Positives = 118/262 (45%), Gaps = 34/262 (12%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQW-DQQFRS--MKELYERKVAELKTKLDAAERFLSTR 89
+++L +K ++K E+ ++ D +F ++EL E L+TK ++ TR
Sbjct: 312 LDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTR 371
Query: 90 EKDP--HQRQRKD----------DRQREDDRQR--DLTRDRLQREEKEKERLNEELH--- 132
+ H+ ++++ + +R+ DR++ +L + + E +K+ ++E LH
Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGW 431
Query: 133 ---------ELKEENKLLKGK--NTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCL 181
EL E + G N L + E E + L K +++ S +
Sbjct: 432 ELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNAS 491
Query: 182 RKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNR 241
+ ++E ++ + ++E+L+ ++ ++ + ++ + L +EK +L++ ET + R
Sbjct: 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSER 551
Query: 242 LNSQIKACQMEKEKLEKQLKQM 263
QIK + E E L + + +
Sbjct: 552 ---QIKILEQENEHLNQTVSSL 570
Score = 40.4 bits (93), Expect = 0.002
Identities = 53/241 (21%), Positives = 101/241 (41%), Gaps = 31/241 (12%)
Query: 34 NSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDP 93
N+L+ +I L++Q L E N Q + ++ + T L L ++
Sbjct: 1077 NNLQAQILALQRQTVSLQEQNTTLQTQNAKL-QVENSTLNSQSTSLMNQNAQLLIQQSSL 1135
Query: 94 HQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLA----N 149
++RED + D L ++ ++ E L+E + E L+ TL N
Sbjct: 1136 ENENESVIKEREDLKS---LYDSLIKDHEKLELLHER--QASEYESLISKHGTLKSAHKN 1190
Query: 150 KEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEE 209
E EH + E R N+ L+ +K ++E + ++ E E + + + +E
Sbjct: 1191 LEVEHRDLE-DRYNQLLK--------------QKGQLEDLEKMLKVEQEKMLLENKNHET 1235
Query: 210 ---DFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLE---KQLKQM 263
++KK + +RLN +L + E Q+ L S + ++E+ +LE +LK+
Sbjct: 1236 VAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQ 1295
Query: 264 Y 264
Y
Sbjct: 1296 Y 1296
Score = 35.4 bits (80), Expect = 0.070
Identities = 48/249 (19%), Positives = 115/249 (46%), Gaps = 20/249 (8%)
Query: 29 RKNLMNSLEQKIRC------LEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTK---L 79
R+ L EQ + C +E + K L + N RS + +Y ++ L+ K +
Sbjct: 264 RQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSAR-MYRDELDALREKAVRV 322
Query: 80 DAAERFLSTREKDPHQRQ---RKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKE 136
D E +S ++ H + + + +ED++ T+ L+ + + +++LHEL++
Sbjct: 323 DKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEK 382
Query: 137 ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTE 196
EN LK K L + E E + + K++ + +++ + ++ + + + + E++
Sbjct: 383 ENLQLKAK--LHDMEMER-DMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRT 439
Query: 197 MEVLKQQVQIYEEDFKKERSDR-ERLNQEKEELQQINETSQSQLNRLN---SQIKACQME 252
E+ + + + + S R +L E + L + E ++ ++ + S+I + E
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE 499
Query: 253 KEKLEKQLK 261
++L K+++
Sbjct: 500 NQRLSKKVE 508
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 71.2 bits (173), Expect = 1e-12
Identities = 57/256 (22%), Positives = 131/256 (51%), Gaps = 16/256 (6%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSM---KELYERK 71
E EH S R+ S E +++ +EK+ K L E ++ + + K +++
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKE 616
Query: 72 VAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEEL 131
+ K K + AE E + H +++++ ++ +T ++++ E+E L E
Sbjct: 617 LEHYKEKGERAEEL----ENELHHLEKENELLQKKITNLKITCEKIEALEQENSELEREN 672
Query: 132 HELKEENKLLKGKN-TLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCH 190
+LK+ K L + EKE+ + + + L + ++ ++KC+ ++ ++++ +
Sbjct: 673 RKLKKTLDSFKNLTFQLESLEKENSQLDEENL-ELRRNVESLKCA----SMKMAQLQLEN 727
Query: 191 EEMRTEMEVLKQQVQIYEEDFKK-ERSD--RERLNQEKEELQQINETSQSQLNRLNSQIK 247
+E+ +E E LK+ +++ + FKK ER + + L+ E + LQ+ E S ++ +L S+++
Sbjct: 728 KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Query: 248 ACQMEKEKLEKQLKQM 263
+ME + L+K L+++
Sbjct: 788 DLEMENQTLQKNLEEL 803
Score = 53.9 bits (128), Expect = 2e-07
Identities = 64/272 (23%), Positives = 111/272 (40%), Gaps = 26/272 (9%)
Query: 10 RMIAAESSTEHK----ECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMK 65
R++ E ST+ + E ST K + E+KI LE + +E NQQ Q+ +++K
Sbjct: 941 RLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVK 1000
Query: 66 ELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKE 125
+ YE LK + D ER + + + + + +E R+ +DRL E+
Sbjct: 1001 KNYE----ALKQRQD-EERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNA 1055
Query: 126 RLNEELHELKEENKLLKGKNTLANKE---KEHYECEIKRLNKALQDALNIKCSFSEDCLR 182
L E LK + K L+ +N + + ++ N LQ N K L
Sbjct: 1056 TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ-TQNAKLQVENSTLN 1114
Query: 183 KSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERL------NQEKEELQQINETSQ 236
++ ++ + + ++ E KER D + L + EK EL + S+
Sbjct: 1115 SQSTSLMNQ--NAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASE 1172
Query: 237 -----SQLNRLNSQIKACQMEKEKLEKQLKQM 263
S+ L S K ++E LE + Q+
Sbjct: 1173 YESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1204
Score = 50.1 bits (118), Expect = 3e-06
Identities = 55/276 (19%), Positives = 111/276 (40%), Gaps = 32/276 (11%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAE 74
E+S +E E + K+ L+ + KEL +Q + +K + +K
Sbjct: 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF-KKTER 753
Query: 75 LKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHEL 134
L+ + +K +K + + + ++ LQ+ +E + ++ L +L
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Query: 135 KEENKLLKGKNTLANKEKEHYECEIKRL------------------------NKALQDAL 170
++ENK L+ + + K+K+ E E KRL NK L +
Sbjct: 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Query: 171 NIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKE---- 226
I + E C+R +E ++E+ + + + ED E+ +++N + E
Sbjct: 874 GI---YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Query: 227 ELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
EL++I + L+ S ++ + KLE LK+
Sbjct: 931 ELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKK 966
Score = 41.6 bits (96), Expect = 0.001
Identities = 51/262 (19%), Positives = 118/262 (45%), Gaps = 34/262 (12%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQW-DQQFRS--MKELYERKVAELKTKLDAAERFLSTR 89
+++L +K ++K E+ ++ D +F ++EL E L+TK ++ TR
Sbjct: 312 LDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTR 371
Query: 90 EKDP--HQRQRKD----------DRQREDDRQR--DLTRDRLQREEKEKERLNEELH--- 132
+ H+ ++++ + +R+ DR++ +L + + E +K+ ++E LH
Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGW 431
Query: 133 ---------ELKEENKLLKGK--NTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCL 181
EL E + G N L + E E + L K +++ S +
Sbjct: 432 ELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNAS 491
Query: 182 RKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNR 241
+ ++E ++ + ++E+L+ ++ ++ + ++ + L +EK +L++ ET + R
Sbjct: 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSER 551
Query: 242 LNSQIKACQMEKEKLEKQLKQM 263
QIK + E E L + + +
Sbjct: 552 ---QIKILEQENEHLNQTVSSL 570
Score = 40.4 bits (93), Expect = 0.002
Identities = 53/241 (21%), Positives = 101/241 (41%), Gaps = 31/241 (12%)
Query: 34 NSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDP 93
N+L+ +I L++Q L E N Q + ++ + T L L ++
Sbjct: 1076 NNLQAQILALQRQTVSLQEQNTTLQTQNAKL-QVENSTLNSQSTSLMNQNAQLLIQQSSL 1134
Query: 94 HQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLA----N 149
++RED + D L ++ ++ E L+E + E L+ TL N
Sbjct: 1135 ENENESVIKEREDLKS---LYDSLIKDHEKLELLHER--QASEYESLISKHGTLKSAHKN 1189
Query: 150 KEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEE 209
E EH + E R N+ L+ +K ++E + ++ E E + + + +E
Sbjct: 1190 LEVEHRDLE-DRYNQLLK--------------QKGQLEDLEKMLKVEQEKMLLENKNHET 1234
Query: 210 ---DFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLE---KQLKQM 263
++KK + +RLN +L + E Q+ L S + ++E+ +LE +LK+
Sbjct: 1235 VAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQ 1294
Query: 264 Y 264
Y
Sbjct: 1295 Y 1295
Score = 35.4 bits (80), Expect = 0.070
Identities = 48/249 (19%), Positives = 115/249 (46%), Gaps = 20/249 (8%)
Query: 29 RKNLMNSLEQKIRC------LEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTK---L 79
R+ L EQ + C +E + K L + N RS + +Y ++ L+ K +
Sbjct: 264 RQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSAR-MYRDELDALREKAVRV 322
Query: 80 DAAERFLSTREKDPHQRQ---RKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKE 136
D E +S ++ H + + + +ED++ T+ L+ + + +++LHEL++
Sbjct: 323 DKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEK 382
Query: 137 ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTE 196
EN LK K L + E E + + K++ + +++ + ++ + + + + E++
Sbjct: 383 ENLQLKAK--LHDMEMER-DMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRT 439
Query: 197 MEVLKQQVQIYEEDFKKERSDR-ERLNQEKEELQQINETSQSQLNRLN---SQIKACQME 252
E+ + + + + S R +L E + L + E ++ ++ + S+I + E
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE 499
Query: 253 KEKLEKQLK 261
++L K+++
Sbjct: 500 NQRLSKKVE 508
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 70.5 bits (171), Expect = 2e-12
Identities = 55/255 (21%), Positives = 124/255 (48%), Gaps = 21/255 (8%)
Query: 29 RKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY---ERKVAELKTKLDAAERF 85
R+ + E+KIR E++ + E+ + +++ R +E+ E K+ EL+ K+ E+
Sbjct: 300 REEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 359
Query: 86 LSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKN 145
EK + + ++ +R++ + ++ RE++EK R EE+ + ++E K+ + +
Sbjct: 360 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ-EQEEKMGEQEE 418
Query: 146 TLANKEKEHYECEIK---RLNKALQDALNIK------------CSFSEDCLRKSRVEFCH 190
+ +E+E E E K + K + I+ E+ + + + C
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 191 EE--MRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKA 248
+E M+ + E +++Q + E KK R E++ +++E +Q+ E Q ++ Q +
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538
Query: 249 CQMEKEKLEKQLKQM 263
Q ++EK+ +Q ++M
Sbjct: 539 MQEQEEKMRRQEEKM 553
Score = 58.2 bits (139), Expect = 1e-08
Identities = 43/228 (18%), Positives = 115/228 (50%), Gaps = 23/228 (10%)
Query: 36 LEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQ 95
L ++++ + + + +E N+ W++ + + E K+ + K+ E + +E+ +
Sbjct: 258 LGKELQSVSAKLQAQVEENELWNR----LNQQQEEKMWRQEEKIQEREEKIQEQEEKIRE 313
Query: 96 RQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHY 155
++ K RQ E +++ ++++R+E+ E++ EL+E K+ + + +EK
Sbjct: 314 QEEKMRRQEEMMWEKE---EKMRRQEEMMWEKEEKIRELEE--KMHEQEKIREQEEKRQE 368
Query: 156 ECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKER 215
E +I+ K + +++++ E++R + E +++Q ++ +E +K
Sbjct: 369 EEKIREQEKRQE--------------QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 216 SDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
E++ +++EE+Q+ E + Q ++ Q K + ++EK+ +Q + M
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462
Score = 48.1 bits (113), Expect = 1e-05
Identities = 59/254 (23%), Positives = 119/254 (46%), Gaps = 22/254 (8%)
Query: 17 STEHKECAEPSTRKNLMNSLE---QKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVA 73
S E ++ A ++ L LE Q IR L Q+ EL ++ + Q ++K+L E +
Sbjct: 94 SPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTEL-QMALYYSQH--AVKQL-EGEAR 149
Query: 74 ELKTKLDAAERFLSTREKD----PHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNE 129
+L ++L + +F E+ Q+++ D E ++RD L R E
Sbjct: 150 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE---- 205
Query: 130 ELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFC 189
ELKE+N L+ K L EK + +K L + L+ A K + L ++ +
Sbjct: 206 ---ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA---KLLLPQQQL-QAEADHL 258
Query: 190 HEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKAC 249
+E+++ L+ QV+ E + + E++ +++E++Q+ E Q Q ++ Q +
Sbjct: 259 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKM 318
Query: 250 QMEKEKLEKQLKQM 263
+ ++E + ++ ++M
Sbjct: 319 RRQEEMMWEKEEKM 332
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/139 (21%), Positives = 71/139 (51%), Gaps = 8/139 (5%)
Query: 25 EPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY---ERKVAELKTKLDA 81
E ++ M E+KIR EK+ +E E ++ ++ + +E E K+ E + K+
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485
Query: 82 AERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLL 141
E + +E+ ++++K Q E R+++ + +Q +E++ E++ E +E K+
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQE---EMMQEQEEKMWEQEEKMCE--QEEKMQ 540
Query: 142 KGKNTLANKEKEHYECEIK 160
+ + + +E++ E E++
Sbjct: 541 EQEEKMRRQEEKMREQEVR 559
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 69.3 bits (168), Expect = 4e-12
Identities = 50/238 (21%), Positives = 126/238 (52%), Gaps = 5/238 (2%)
Query: 29 RKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLST 88
++ +M E+KIR LE++ E ++ +Q +++ K + K E + K+ E +
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 488
Query: 89 REKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLA 148
+E+ +++ K RQ E +++ R+ +R+E+E+ EE +++E+ ++ + K +
Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE--KIREQEEIWRQKEKIH 546
Query: 149 NKEKEHYECEIK--RLNKALQD-ALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQ 205
+E++ + E K R + + D I+ + ++ ++ E++R + E +++Q +
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Query: 206 IYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
+ +E +K E++ +++E++Q+ E + Q ++ Q K + ++EK+ +Q + M
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Score = 66.6 bits (161), Expect = 3e-11
Identities = 49/232 (21%), Positives = 113/232 (48%), Gaps = 14/232 (6%)
Query: 44 EKQRKELLEVNQQWDQQ--FRSMKELY---ERKVAELKTKLDAAERFLSTREKDPHQRQR 98
EK+ K + W+++ R +E+ E K+ EL+ K+ E+ EK + +
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 466
Query: 99 KDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECE 158
++ +R++ + ++ RE++EK R EE +EE + + + +EK + E
Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK--IHEQEKIREEEKRQEQEE 524
Query: 159 IKRLNKALQDALNI-----KCSFSEDCLRKSRVEFCHEE--MRTEMEVLKQQVQIYEEDF 211
+ R + +++ I K E+ +RK + +E M + E +++Q +
Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE 584
Query: 212 KKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
+K R E++ +++E++++ E +Q Q ++ Q + ++EK+++Q ++M
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636
Score = 60.5 bits (145), Expect = 2e-09
Identities = 54/250 (21%), Positives = 123/250 (49%), Gaps = 30/250 (12%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKEL-YERKVAELKTKLDAAERFLSTREKDPHQ 95
++KIR E++R+E ++ +Q +Q + K E K+ E + K+ E + +E+ H+
Sbjct: 450 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE 509
Query: 96 RQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHEL-----KEENKLLKGKNTLANK 150
+++ + ++ +++ ++ RE++E R E++HE K+E K+ + + + ++
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ 569
Query: 151 EKEHYECEIK----------RLNKALQDALNIK-----CSFSEDCLRKSRVEFCHEE--M 193
E++ E E K + K + I+ E+ + + + C +E M
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 629
Query: 194 RTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEK 253
+ + E +++Q + E KK R E++ +++E +Q+ E Q + K C+ E
Sbjct: 630 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ------EEKMCEQE- 682
Query: 254 EKLEKQLKQM 263
EK+++Q ++M
Sbjct: 683 EKMQEQEEKM 692
Score = 53.5 bits (127), Expect = 2e-07
Identities = 47/251 (18%), Positives = 120/251 (47%), Gaps = 22/251 (8%)
Query: 36 LEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY---ERKVAELKTKLDAAERFLSTREKD 92
L ++++ + + + +E N+ W++ + +E E K+ E + K+ E + +E+
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 390
Query: 93 PHQRQRKDDRQRE---DDRQRDLTRDRLQREEKEKERLNEELHELKEEN------KLLKG 143
+++ K RQ E + ++ ++ + E++EK R EE+ KEE K+ +
Sbjct: 391 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 144 KNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQ 203
+ +EK E +I+ K + + + ++ ++ E+M + E + +Q
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510
Query: 204 VQIYEEDFKKERSD----------RERLNQEKEELQQINETSQSQLNRLNSQIKACQMEK 253
+I EE+ ++E+ + +E + ++KE++ + E + Q ++ Q + ++
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 254 EKLEKQLKQMY 264
EK+ +Q ++++
Sbjct: 571 EKIREQEEKVW 581
Score = 52.4 bits (124), Expect = 6e-07
Identities = 54/252 (21%), Positives = 114/252 (45%), Gaps = 16/252 (6%)
Query: 17 STEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELK 76
S E ++ A ++ L LE ++ + + E+ ++K+L E + +L
Sbjct: 167 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQL-EGEARDLI 225
Query: 77 TKLDAAERFLSTREKD----PHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELH 132
++L + +F E+ Q+++ D E ++RD L R E
Sbjct: 226 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE------- 278
Query: 133 ELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE 192
ELKE+N L+ K L EK + +K L + L+ A K + L ++ + +E
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA---KLLLPQQQL-QAEADHLGKE 334
Query: 193 MRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQME 252
+++ L+ QV+ E + + E++ +++E++Q+ E Q Q ++ Q + + +
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 394
Query: 253 KEKLEKQLKQMY 264
+EK+ +Q + M+
Sbjct: 395 EEKMRRQEEMMW 406
Score = 52.4 bits (124), Expect = 6e-07
Identities = 54/280 (19%), Positives = 135/280 (48%), Gaps = 34/280 (12%)
Query: 10 RMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELL----EVNQQWDQQFRSMK 65
+ + AE+ KE S + + L +Q++E + E Q+W+++ + +
Sbjct: 322 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 381
Query: 66 ELY---ERKVAELKTKLDAAERFLSTREKDPH-------QRQRKDDRQRE-----DDRQR 110
E E K+ E + K+ E + +E+ +++ K RQ E +++ R
Sbjct: 382 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 111 DLTRDRLQREEK---------EKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKR 161
+L +++ +EK E+E++ E+ ++E K+ + + + +E++ E E K
Sbjct: 442 EL-EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 162 LNKALQDALNIKCSFSEDCLRKSRVEFCHEE--MRTEMEVLKQQVQIYEEDFKKERSDRE 219
+ ++ ++ + E+ R+ + E +E +R + E+ +Q+ +I+E++ +K R E
Sbjct: 501 WRQ--EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE-EKIRKQEE 557
Query: 220 RLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQ 259
++ +++E++ E + Q ++ Q + + ++EK+ +Q
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQ 597
Score = 42.0 bits (97), Expect = 7e-04
Identities = 53/231 (22%), Positives = 113/231 (48%), Gaps = 21/231 (9%)
Query: 48 KELLEVNQQWDQQFR---SMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQR 104
+EL E N + ++ + S K + V ELK KL+ A+ L P Q+ + +
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL------PQQQLQAEADHL 331
Query: 105 EDDRQRDLTRDRLQREEKEK-ERLNEELHEL--KEENKLLKGKNTLANKEKEHYECE--I 159
+ Q + + Q EE E RLN++ E ++E K+ + + + +E++ E E I
Sbjct: 332 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 391
Query: 160 KRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE-MRTEMEVL---KQQVQIYEEDFKKER 215
+ + ++ + E R+ + + EE MR + E++ +++++ EE ++
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 451
Query: 216 SDRER--LNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
RE+ QE+E++++ E Q Q ++ Q + + ++EK+ +Q ++M+
Sbjct: 452 KIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Score = 38.5 bits (88), Expect = 0.008
Identities = 41/220 (18%), Positives = 102/220 (46%), Gaps = 42/220 (19%)
Query: 21 KECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY----------ER 70
+E E +K ++ E+KIR E++ E +++ R +E E
Sbjct: 533 REQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Query: 71 KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
K+ E + K+ E +E+ +++ K Q E ++++ ++++R+E E++ E+
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE---EKMRRQE---EKIREQ 646
Query: 131 LHELKE-ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFC 189
+++E E K+ + + + +E++ +E E K C ++ +++
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKM------------------CEQEEKMQEQ 688
Query: 190 HEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQ 229
E+MR +Q+ +++E++ + R E++ + +E L+
Sbjct: 689 EEKMR------RQEEKMWEQEVRL-RQQEEKMQEHQEHLE 721
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 69.3 bits (168), Expect = 4e-12
Identities = 59/234 (25%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 38 QKIRCLEKQRKELL-EVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
+K + L+++ ++LL E ++ +Q R K E ++ + + +L ER R++ Q
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKE--- 153
++KD+ Q+E+ ++L REE+EK RL E + +EE +L + + L +E+E
Sbjct: 1021 RKKDELQQEE--------EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Query: 154 --HYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDF 211
E + ++ + Q+ + E R+ R C EE + E ++ + EE
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE---EEQLLREERE 1129
Query: 212 KKERSDRERLNQEKEELQQINE--TSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
K+ R + ER +E+EE+QQ E + R +++ E+E+L+++ +Q+
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
Score = 66.2 bits (160), Expect = 4e-11
Identities = 53/226 (23%), Positives = 111/226 (49%), Gaps = 22/226 (9%)
Query: 45 KQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQR 104
K+R+ L +Q R ++L + + EL+ RE+ +R+++ +RQ
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ------------REEREKRRRQEQERQY 930
Query: 105 EDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNK 164
++ Q ++L REE+EK R E + +++ KL + + L +E E + +
Sbjct: 931 REEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 165 ALQDALNIKCSFSEDCLRKSRVEFCHEE----MRTEMEVLKQQVQIYEEDFKKER-SDRE 219
++ L + E LR+ R + +E R + E+ +++ Q+ E+ +K R +RE
Sbjct: 991 REEEELQQE---EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Query: 220 RLNQEKEELQQINE--TSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
R +E+EELQQ E + + R +++ ++E+L+++ +Q+
Sbjct: 1048 RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Score = 65.5 bits (158), Expect = 6e-11
Identities = 60/258 (23%), Positives = 128/258 (49%), Gaps = 31/258 (12%)
Query: 19 EHKECAEPSTRKNLMNSL-EQKIRCLEKQRKELLEVNQQWDQQFRSMKELY--ERKVAEL 75
E + + ++++L + L EQ+ R E++R+ QQ D+ F ++L E+K A+
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRW----QQRDRHFPEEEQLEREEQKEAKR 1309
Query: 76 KTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDR--LQREEKEKERLNEELHE 133
+ + E+ L E++ +R+++ DR+ ++ Q R+ L+R+E++++ EEL
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
Query: 134 LKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSR-VEFCHEE 192
++ K L+ + L +E+E K L++ ++C E LR+ R +F EE
Sbjct: 1370 QEQGRKFLEEEQRLRRQERE---------RKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 193 MRTEMEVLKQQVQIYEEDFKKERSDRERLNQE-----------KEELQQINETSQSQLNR 241
+ + ++ + E+ +++ +R+ L +E +EE Q + E + QL+R
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
Query: 242 LNSQIKACQMEKEKLEKQ 259
K + E+++L +Q
Sbjct: 1481 QERDRKFLE-EEQQLRRQ 1497
Score = 65.1 bits (157), Expect = 8e-11
Identities = 62/237 (26%), Positives = 122/237 (51%), Gaps = 39/237 (16%)
Query: 37 EQKIRCLEKQRKELLEVNQ-QWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQ 95
EQ++R E++RK L E Q + ++ + +++ +RK E + +L ER RE++ Q
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE--Q 1437
Query: 96 RQRKDDRQR---EDDRQRDLTRDRLQREEKE--KERLNEELHELKEENKLLKGKNTLANK 150
+ R+ +R+R E+++Q R R REE++ +ER ++LH + + K L+ + L +
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497
Query: 151 EKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVE--FCHEEMRT-----EMEVLKQQ 203
E++ F E LR E F EE + + + L+++
Sbjct: 1498 ERDR--------------------KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE 1537
Query: 204 VQIY-EEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQ 259
Q+ +E ++ R DR+R +E+E+L+Q E + QL+R + + ++E++K+ +Q
Sbjct: 1538 QQLRRQERGQQRRQDRDRKFREEEQLRQ--EREEQQLSR-QERDRKFRLEEQKVRRQ 1591
Score = 64.3 bits (155), Expect = 1e-10
Identities = 54/247 (21%), Positives = 119/247 (48%), Gaps = 12/247 (4%)
Query: 19 EHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTK 78
+ +E E R+ EQ++R ++ R+E QQ ++ + +E R+ +L+ +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRRE-----QQLRREQQLRREQQLRREQQLRRE 422
Query: 79 LDAAERFLSTREKDPHQRQRKDDR-QREDDRQRDLTRDRLQREEKEKERLNEELHELKEE 137
R + H+++R++ R +RE + +RD + + E E+ER ++L +EE
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
Query: 138 NKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEM 197
+ + + +E E ++L + ++ + E+ R + +++R E
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 198 EVLKQQVQIYEEDFKKERSDRE-RLNQEKEE-----LQQINETSQSQLNRLNSQIKACQM 251
E ++Q+ EE+ + E+ RE RL +E+EE L++ E Q +L R + ++
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Query: 252 EKEKLEK 258
++E++E+
Sbjct: 603 KREEVER 609
Score = 63.5 bits (153), Expect = 2e-10
Identities = 63/270 (23%), Positives = 135/270 (50%), Gaps = 29/270 (10%)
Query: 10 RMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYE 69
+ + E ++ E +K+ EQ+++ +++R++ L+ ++ ++ + E
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ------E 470
Query: 70 RKVAELKT--KLDAAERFLSTREKDPHQRQRKDDRQ--REDDRQRDLTRDRLQREEKEKE 125
R+ +LK + + ER+L E++ ++Q + ++Q RE + +R+ R + EE+ ++
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 126 RLNEELH---ELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLR 182
RL E E +E + L + E+E E +KR + +D L + E+ R
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR----EEERR 586
Query: 183 KSRVEFCHEEM------RTEMEVLKQQVQIYEEDFKKERSDRER----LNQEKEELQQIN 232
+ R++ EE R E+E L+Q+ + E+ K+E + ER L E++E ++
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEER-REQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Query: 233 ETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
+ + Q R ++K + E+E+LE++LK+
Sbjct: 646 QLRREQQERREQRLKR-EEEEERLEQRLKR 674
Score = 62.8 bits (151), Expect = 4e-10
Identities = 53/253 (20%), Positives = 127/253 (50%), Gaps = 11/253 (4%)
Query: 19 EHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTK 78
+ +E E R+ ++ E+K++ E QR+ L+ ++ ++ + ER+ E + +
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 79 LDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRD----RLQREEKEKERLNEELHEL 134
E+ L ++++ + Q+++ R++++ R++ R R ++EE+ +++L E E
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 135 KEENKLLKGKNTLANKEKEHYECEIKRLN--KALQDALNIKCSFSEDCLRKSRVEFCHEE 192
+ E +L + + +++ E +++R + Q + E LR+ + ++
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 193 MRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEE----LQQINETSQSQLNRLNSQIKA 248
+R E ++ ++Q + E ++ +RL +E+EE L++ ET + + R Q+K
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
Query: 249 CQMEKEKLEKQLK 261
Q E+E+ E+ LK
Sbjct: 479 DQ-EEERRERWLK 490
Score = 61.2 bits (147), Expect = 1e-09
Identities = 54/238 (22%), Positives = 120/238 (50%), Gaps = 18/238 (7%)
Query: 29 RKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLST 88
+K+ + E+++ E++++ L Q+ ++Q+R +EL + + +L ER
Sbjct: 1022 KKDELQQEEEQLLREEREKRRL----QERERQYREEEELQQEE-----EQLLGEERETRR 1072
Query: 89 REKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLA 148
R++ Q +++++ Q+E+++ ++ +R+E+E++ EE + +EE L + +
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 149 NKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYE 208
+E E E + + + + L E+ ++ R E + R E E+ +++ Q+
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLR------EEPEKRRRQEL-ERQYREEEELQQEEEQLLR 1185
Query: 209 EDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIK-ACQMEKEKLEKQLKQMYC 265
E+ +K R +RER +E+EELQ+ + + S +K + EKE + K +YC
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK-VYC 1242
Score = 61.2 bits (147), Expect = 1e-09
Identities = 66/240 (27%), Positives = 113/240 (47%), Gaps = 25/240 (10%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
EQK+R E++RK +E QQ +Q + ER K E+ L RE+ R
Sbjct: 1585 EQKVRRQEQERK-FMEDEQQLRRQEGQQQLRQERD-----RKFREDEQLLQEREEQQLHR 1638
Query: 97 QRKDDRQREDDRQ--RDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEH 154
Q +D + E++ Q R +L+ + K R E+L + EE +L + + +E+E
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 155 YECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMR--TEMEVLKQQVQ----IYE 208
+R K LQ+ ++ ++ RK R E E++R TE E L++Q + + E
Sbjct: 1699 QLRRQERERKFLQEEQQLR---RQELERKFREE---EQLRQETEQEQLRRQERYRKILEE 1752
Query: 209 EDFKKERSDRERLNQE-----KEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
E + ER +++ QE +EE Q E + QL S K + E+ + E++ +Q+
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Score = 60.5 bits (145), Expect = 2e-09
Identities = 70/284 (24%), Positives = 132/284 (46%), Gaps = 52/284 (18%)
Query: 27 STRKNLMNSLEQKIRCLEKQRKE--LLEVNQQWDQQFRSMKEL-YERKVAELKTKLDAAE 83
S R L E+++R E+Q++E L ++ +Q+ R +E E + E + +L E
Sbjct: 785 SARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 84 RFLSTREKDP----------HQRQRKDDR---QREDDRQR-------------------- 110
R +E++ Q QR+D + Q E++R+R
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 111 --DLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQD 168
+ LQREE+EK R E+ + +EE +L + + L +E+E + +R + Q
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE----KRRRQERERQY 960
Query: 169 ALNIKCSFSEDCL-----RKSRVEFCHEEMRTEMEVLKQQVQIY-EEDFKKERSDRERLN 222
+ K E+ L K R + ++ R E E+ +++ Q+ EE K+ R + ER
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 223 QEKEELQQINE---TSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
++K+ELQQ E + + RL + + + E+E+L+++ +Q+
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYR-EEEELQQEEEQL 1063
Score = 60.1 bits (144), Expect = 3e-09
Identities = 59/238 (24%), Positives = 117/238 (49%), Gaps = 29/238 (12%)
Query: 44 EKQRKELLEVNQQWDQQFRSMKELYERKVAELK----TKLDAAERFLSTREKDPHQRQRK 99
E+Q +E ++ Q+ +Q R +E R+ E + KL E L E + +RQ +
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 100 DDRQREDDRQRDLT-------RDRLQREEKEKE-RLNEELHELKEENKLL---KGKNTLA 148
+ + RE++ + R++ +R+E E++ R +EL + EE +LL + K L
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ--EEEQLLREEREKRRLQ 1044
Query: 149 NKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIY- 207
+E+++ E + LQ + R+ +E + R E E+ +++ Q+
Sbjct: 1045 ERERQYRE------EEELQQEEEQLLGEERETRRRQELE---RQYRKEEELQQEEEQLLR 1095
Query: 208 EEDFKKERSDRERLNQEKEELQQINE--TSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
EE K+ R +RER +E+EELQQ E + + R +++ E+E+++++ +Q+
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Score = 59.3 bits (142), Expect = 4e-09
Identities = 58/258 (22%), Positives = 128/258 (49%), Gaps = 14/258 (5%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELL----EVNQQWDQQFRSMKELYER 70
E E +E E R+ EQ++R +++R+E + ++ +QQ R +E ER
Sbjct: 316 EQQEERREQQE--RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE-EER 372
Query: 71 KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDR-LQREEKEKERLNE 129
+ +L+ + R R + +R+++ R+++ R++ L R++ L+RE++ + E
Sbjct: 373 REQQLRRE-QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 130 ELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSR-VEF 188
E HE K E + + + +E+ + + + Q+ + ++ R+ R ++
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 189 CHEEMRTEMEVLKQQVQIYEEDFKKERSDR----ERLNQEKEELQQINETSQSQLNRLNS 244
EE R + E +QQ++ +E+ +++R R ERL Q QQ+ + + +L
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 245 QIKACQMEKEKLEKQLKQ 262
+ + ++E+E+ E++LK+
Sbjct: 552 REEEKRLEQERREQRLKR 569
Score = 58.9 bits (141), Expect = 6e-09
Identities = 53/252 (21%), Positives = 119/252 (47%), Gaps = 12/252 (4%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSM--KELYERKV 72
E E ++ + L E++ R +++R+E E +Q +++ +E ER+
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 73 AELKTKLDAAERFLSTR-EKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKE--KERLNE 129
+L+ + + R R E++ +R+++ R+++ R++ L R++ R E++ +E+
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Query: 130 ELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFC 189
+L+ E +L + + +E+E + E K + + L + D L++
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERH--EQKHEQERREQRLKREQEERRDWLKREEETER 466
Query: 190 HEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKAC 249
HE+ R + ++ + Q + E + K + R QE+ E Q E + + RL
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR----- 521
Query: 250 QMEKEKLEKQLK 261
Q E+E+L+++L+
Sbjct: 522 QEEEERLQQRLR 533
Score = 58.5 bits (140), Expect = 8e-09
Identities = 64/266 (24%), Positives = 126/266 (47%), Gaps = 27/266 (10%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAE 74
E TE E + E++ R L+ + +E E ++ +QQ R +E ER+
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE--ERREQR 518
Query: 75 LKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHE- 133
LK + + E L R + Q +R+ + +RE +R+ + RL++E +E +RL E E
Sbjct: 519 LKRQEE--EERLQQRLRSEQQLRREQEERREQLLKREEEK-RLEQERRE-QRLKREQEER 574
Query: 134 ----LKEENKLLKGKNTLANKEKEHYEC-----EIKRLNKALQDALNIKCSFSEDCLRKS 184
LK E + + + L +++E E E++RL + + +K E+ R+
Sbjct: 575 RDQLLKREEE--RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632
Query: 185 RVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSD---RERLNQEKEELQQINETSQSQLNR 241
++ +E R + ++ ++Q + E+ K+E + +RL +E EE ++ E ++ + +
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Query: 242 LNSQIKA------CQMEKEKLEKQLK 261
+IK+ Q+E E +Q K
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSK 718
Score = 57.4 bits (137), Expect = 2e-08
Identities = 55/241 (22%), Positives = 111/241 (46%), Gaps = 23/241 (9%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
EQ++ E+ RK LE QQ +Q R +RK E + + ER E+ H++
Sbjct: 1475 EQQLHRQERDRK-FLEEEQQLRRQER------DRKFREQELRSQEPERKFLEEEQQLHRQ 1527
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKE-RLNEELHELKEENKLLKGKNTLANKEKEHY 155
QR+ +E+ + R R + +R++++++ R E+L + +EE +L + + + +E
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK 1587
Query: 156 ECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFK--- 212
++ K ++D ++ + LR+ R E+ + E +QQ+ E D K
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 213 ------------KERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQL 260
+ R DR+R +E+E+L Q E Q + + + + + + + E++
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 261 K 261
K
Sbjct: 1708 K 1708
Score = 57.0 bits (136), Expect = 2e-08
Identities = 48/220 (21%), Positives = 111/220 (50%), Gaps = 12/220 (5%)
Query: 46 QRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQRE 105
+R+ELLE+ ++ ++ + + + +V + + + + +R R+++ ++ + RQRE
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 106 DDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKA 165
+ + R +L+R+E +ER EE +++ +L + + +E+E E + +R +
Sbjct: 271 LQEEEEQLR-KLERQELRRERQEEE----QQQQRLRREQQLRRKQEEERREQQEER--RE 323
Query: 166 LQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEK 225
Q+ + E LR+ + E +++R E E +++ Q+ E ++ R + R Q+
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 226 EELQQINETSQSQLNRLNSQIKACQMEKE---KLEKQLKQ 262
QQ+ + QL R + Q+ +E + E+QL++
Sbjct: 384 RREQQLRR--EQQLRREQQLRREQQLRREQQLRREQQLRR 421
Score = 57.0 bits (136), Expect = 2e-08
Identities = 52/221 (23%), Positives = 105/221 (47%), Gaps = 27/221 (12%)
Query: 29 RKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLST 88
RK L + + + LE++ +E ++ Q+ +Q+ +E Y + + E + + + E+ L
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Query: 89 REKDPHQRQRKDDRQ-REDDRQRDLTRDRLQREEKE--KERLNEELHELKEENKLLKGKN 145
+E+D R+ + RQ RE+ + R DR REE++ +ER ++L + + K +
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 146 TLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQ 205
L +E+E +RL + + R E+ T+ + +++ +
Sbjct: 1827 QLQLEEQE------QRLRQ-----------------ERDRQYRAEEQFATQEKSRREEQE 1863
Query: 206 IYEEDFKKERSDRER-LNQEKEELQQINETSQSQLNRLNSQ 245
+++E+ +K R +RER L +E QQ E Q+ + SQ
Sbjct: 1864 LWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Score = 56.2 bits (134), Expect = 4e-08
Identities = 50/226 (22%), Positives = 104/226 (46%), Gaps = 32/226 (14%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
EQ++R E++RK L E Q ++ R +E E+ L RE+ R
Sbjct: 1436 EQQVRRQERERKFLEEEQQLRQERHRKFRE---------------EEQLLQEREEQQLHR 1480
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYE 156
Q +D + E+++Q L+R+E++++ +EL + E K L+ + L ++++
Sbjct: 1481 QERDRKFLEEEQQ-------LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ--- 1530
Query: 157 CEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERS 216
K LQ+ ++ R+ R EE + E +QQ+ E D +K R
Sbjct: 1531 ------RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD-RKFRL 1583
Query: 217 DRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
+ +++ ++++E + + + Q + Q++ + K + ++QL Q
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Score = 55.5 bits (132), Expect = 6e-08
Identities = 56/264 (21%), Positives = 126/264 (47%), Gaps = 10/264 (3%)
Query: 7 GTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKE 66
G ++ E + EP R+ +++ + ++Q +EL E +Q ++Q R +
Sbjct: 105 GKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQR 164
Query: 67 LYERKVAEL-KTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQ-----RE 120
+R+ EL + + + ER E++ Q + + + D ++ R+ L+ RE
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 121 EKEKERLNEELHELKEEN-KLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSED 179
EK+++R + +EE K + + T+ KE+E + E + + LQ+
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 180 CLRKSRVEFCHEEMRTEMEV-LKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQ 238
LR+ R E ++ R E L+++ + + ++ER +++ +++EE ++ + + Q
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE-QQLRREQ 343
Query: 239 LNRLNSQIKACQMEKEKLEKQLKQ 262
R Q++ + E+E+ E+QL++
Sbjct: 344 EERREQQLRR-EQEEERREQQLRR 366
Score = 55.5 bits (132), Expect = 6e-08
Identities = 55/227 (24%), Positives = 107/227 (47%), Gaps = 16/227 (7%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
EQ R +K+ K +Q+ Q R +E +R+ E K E+ L RE+ P +R
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREERE-EKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE--LHELKEENKLLKGKNTLANKEKEH 154
Q +D + RE++ L+ +E+ ++ L EE L + E K LK + L +E+E
Sbjct: 1356 QERDRKFREEE---------LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406
Query: 155 YECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKE 214
+ R K ++ + + R+ + +E E + L+++ Q+ +E +K
Sbjct: 1407 -QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE--RERKFLEEEQQLRQERHRKF 1463
Query: 215 RSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLK 261
R + E+L QE+EE Q + + Q++ + +++ E++L+
Sbjct: 1464 R-EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Score = 55.1 bits (131), Expect = 8e-08
Identities = 55/271 (20%), Positives = 125/271 (46%), Gaps = 32/271 (11%)
Query: 19 EHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQW---------DQQFRSMK--EL 67
+ +E AE + LEQ+ R +++ +EL Q+W ++Q +S K E
Sbjct: 144 QERELAEGEEQSEKQERLEQRDR--QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET 201
Query: 68 YERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTR---------DRLQ 118
E E + + E RE+ QR+ + DR +++ +++ + ++LQ
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 119 REEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSE 178
EE +++R EL E +E+ + L+ + +++E + + R + L+ + +
Sbjct: 262 EEEPQRQR---ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 179 DCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRER----LNQEKEELQQINET 234
+ R+ + +E R E ++ ++Q + E+ ++E+ + R +++EE ++
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 235 SQSQLNRLNSQIKACQMEKE---KLEKQLKQ 262
+ QL R + Q+ +E + E+QL++
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRR 409
Score = 55.1 bits (131), Expect = 8e-08
Identities = 52/254 (20%), Positives = 113/254 (44%), Gaps = 15/254 (5%)
Query: 9 SRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY 68
SR E +E E R+ +++ R +Q++E + W Q E
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
Query: 69 ERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLN 128
++++ + ER L E+ +++ + + ++ R+R QR E+EK
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR-------QRREREK---- 829
Query: 129 EELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEF 188
EL L+EE +L + + +E+E E + ++ + + K + + RK R
Sbjct: 830 -ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 189 CHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKA 248
+ + + ++ K+Q + EE+ + +R +RE+ ++++E Q E QL + Q+
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE---EQLQQEEEQLLR 945
Query: 249 CQMEKEKLEKQLKQ 262
+ EK + +++ +Q
Sbjct: 946 EEREKRRRQERERQ 959
Score = 55.1 bits (131), Expect = 8e-08
Identities = 54/226 (23%), Positives = 106/226 (46%), Gaps = 29/226 (12%)
Query: 43 LEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDR 102
L ++R+E Q+ D++FR ++ R+ E K D E+ L +E RQ +D +
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED--EQQLRRQEGQQQLRQERDRK 1620
Query: 103 QREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHY-----EC 157
RED++ +REE++ LH + + K L+ + L +E+E +
Sbjct: 1621 FREDEQLLQ------EREEQQ-------LHRQERDRKFLEEEPQLRRQEREQQLRHDRDR 1667
Query: 158 EIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSD 217
+ + + LQ+ E LR+ + E ++ +++ + +E+ + R +
Sbjct: 1668 KFREEEQLLQEG-------EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQE 1720
Query: 218 RERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
ER +E+E+L+Q ET Q QL R K + E+ + E++ +Q+
Sbjct: 1721 LERKFREEEQLRQ--ETEQEQLRRQERYRKILEEEQLRPEREEQQL 1764
Score = 53.5 bits (127), Expect = 2e-07
Identities = 52/244 (21%), Positives = 116/244 (47%), Gaps = 20/244 (8%)
Query: 38 QKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVA-------ELKTKLDAAERFLSTRE 90
Q+ R +++++ E QW ++ R+ ++ E + + + K + + LS R
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 91 KDPHQRQRK---DDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTL 147
QR+R+ ++RQ+ + R ++ QR + +ER +EL L+EE +L + +
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER-EKELQFLEEEEQLQRRERAQ 847
Query: 148 ANKEKEH--YECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQ 205
+E+E E + +R ++ + + E+ R+ + ++ ++ +Q +Q
Sbjct: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
Query: 206 IYEEDFKKE------RSDRERLNQEKEELQQINE-TSQSQLNRLNSQIKACQMEKEKLEK 258
EE+ ++E R ++ER +E+E+LQQ E + + + Q + Q K+K +
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 259 QLKQ 262
Q ++
Sbjct: 968 QKEE 971
Score = 50.1 bits (118), Expect = 3e-06
Identities = 51/228 (22%), Positives = 101/228 (44%), Gaps = 13/228 (5%)
Query: 43 LEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTK----LDAAERFLSTREKDPHQRQR 98
LE+Q ++ E+ Q+ +Q R E R+ E + + L E L E++ +RQ
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 99 KDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECE 158
+ + RE++ + ++L REE EK R E + +EE +L + + L +E+E E
Sbjct: 1136 LERQYREEEEVQQ-EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Query: 159 IKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDR 218
+R + ++ K ++ R E +++ + E K+ + + K R +
Sbjct: 1195 RERQYREEEELQRQKRK------QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENE 1248
Query: 219 ERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMYCP 266
+ E +L+ + SQ L L + + E+E+ Q + + P
Sbjct: 1249 QFRQLEDSQLR--DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Score = 50.1 bits (118), Expect = 3e-06
Identities = 54/230 (23%), Positives = 105/230 (45%), Gaps = 27/230 (11%)
Query: 37 EQKIRCLEKQRKELLEV----NQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKD 92
EQ++ E+ RK L E Q+ +QQ R ++ RK E + L E R++
Sbjct: 1633 EQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD---RKFREEEQLLQEGEEQQLRRQER 1689
Query: 93 PHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEK 152
+ + ++ + R +R+R ++ Q +E ER E +L++E + + L +E+
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE----QEQLRRQER 1745
Query: 153 EHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFK 212
E ++L ++ + R+ R EE + E +QQ++ E D
Sbjct: 1746 YRKILEEEQLRPEREE---------QQLRRQERDRKFREEEQLRQEREEQQLRSQESD-- 1794
Query: 213 KERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
++ + E+L QE+EE QQ+ + R + Q++ E+ E++L+Q
Sbjct: 1795 RKFREEEQLRQEREE-QQLRPQQRDGKYRWEEE----QLQLEEQEQRLRQ 1839
Score = 49.7 bits (117), Expect = 4e-06
Identities = 55/257 (21%), Positives = 120/257 (46%), Gaps = 25/257 (9%)
Query: 28 TRKNLMNSLEQKIRCLEKQRK---------ELLEVNQQWDQQFRSMKELYERKVAEL--- 75
T+K+L N LE++ + ++ ELL+++ F L+ KVA+
Sbjct: 29 TKKDLKNLLEREFGAVLRRPHDPKTVDLILELLDLDSNGRVDFNEFL-LFIFKVAQACYY 87
Query: 76 ----KTKLDAAERF-LSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
T LD +R +E R++++D++R + R R L + QR ++++ E
Sbjct: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE 147
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSE--DCLRKSRVEF 188
L E +E+++ + L ++++ + E+ R + Q+ + + C EF
Sbjct: 148 LAEGEEQSEK---QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 189 CHEEM--RTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQI 246
EE R E+ L+++ + ++ ++ER DR +E++E ++ + + +L +
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 247 KACQMEKEKLEKQLKQM 263
Q E ++ E+QL+++
Sbjct: 265 PQRQRELQEEEEQLRKL 281
Score = 48.9 bits (115), Expect = 6e-06
Identities = 55/255 (21%), Positives = 115/255 (45%), Gaps = 21/255 (8%)
Query: 19 EHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTK 78
E K + + L E++ L K+ +E + + +Q+ R + L +V L+ +
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613
Query: 79 LDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRD-------RLQREEKEKERLNEEL 131
+R ++ ++Q ++E+ RQ+ L R+ RL+REE E+ERL +
Sbjct: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE-EEERLEQ-- 670
Query: 132 HELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHE 191
LK E++ + + LA +E+E IK Q L SE R+S+V
Sbjct: 671 -RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE-----SEADARQSKVYSRPR 724
Query: 192 EMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINE-----TSQSQLNRLNSQI 246
+ + +Q+ + + + + + ER +++++E +Q + ++ + R ++
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784
Query: 247 KACQMEKEKLEKQLK 261
A +E+ E+QL+
Sbjct: 785 SARPPLREQRERQLR 799
Score = 47.0 bits (110), Expect = 2e-05
Identities = 57/246 (23%), Positives = 119/246 (48%), Gaps = 23/246 (9%)
Query: 19 EHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTK 78
E + + L + ++K R + ++LL+ ++ QQ R + +RK E + +
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFR----EEEQLLQEGEE--QQLRRQER--DRKFREEEQQ 1699
Query: 79 LDAAER---FLSTREKDPHQRQRKDDRQREDDRQRDLT-RDRLQREEKEKERLNEE-LHE 133
L ER FL +E+ +RQ + + RE+++ R T +++L+R+E+ ++ L EE L
Sbjct: 1700 LRRQERERKFL--QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Query: 134 LKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEM 193
+EE +L + + +E+E E R + L+ + + E+ LR+ R E +++
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQE--REEQQLRSQESDRKFREEEQLRQEREE---QQL 1812
Query: 194 RTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEK 253
R + K + +EE+ + +RL QE++ + E +Q + + Q E+
Sbjct: 1813 RPQQRDGKYR---WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE 1869
Query: 254 EKLEKQ 259
+K ++
Sbjct: 1870 QKRRQE 1875
Score = 43.5 bits (101), Expect = 3e-04
Identities = 62/272 (22%), Positives = 127/272 (46%), Gaps = 26/272 (9%)
Query: 6 QGTSRMIAAESSTEHKECAEPSTRKN--LMNSLEQKIRCLEKQRKELLEVNQQWDQQFRS 63
Q +++ E T ++ E RK L EQ +R ++R+ Q+ ++Q R
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR-----QERERQCRE 1112
Query: 64 MKELY---ERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
+EL E+ + E + K E RE++ Q++ + + E +++R +R RE
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQD-ALNIKCSF--- 176
E+E ++ E+L L+EE + + + +E+E + + ++ +D ++K +
Sbjct: 1173 EEELQQEEEQL--LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 177 SEDCLRKSRVEFC----HEEMR--TEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQ 230
E+ +R ++V +C +E+ R + ++ +Q Q + E+ +R+R QE+ QQ
Sbjct: 1231 KENAVRDNKV-YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR-EQERRRWQQ 1288
Query: 231 INE--TSQSQLNRLNSQIKACQMEKEKLEKQL 260
+ + QL R + + K + EKQL
Sbjct: 1289 RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 66.6 bits (161), Expect = 3e-11
Identities = 50/234 (21%), Positives = 114/234 (48%), Gaps = 16/234 (6%)
Query: 44 EKQRKELLEVNQQWDQQ--FRSMKELY---ERKVAELKTKLDAAERFLSTREKDPHQRQR 98
EK+ K + W+++ R ++E+ E K+ EL+ K+ E+ EK + +
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 405
Query: 99 KDDRQREDD-----RQRDLTRD---RLQREEKEKERLNEELHE---LKEENKLLKGKNTL 147
++ +R++ RQ + R+ +++ +EK+ R E++HE ++EE K + +
Sbjct: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
Query: 148 ANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIY 207
+EK + EI R + + + I+ + ++ ++ E++R + E + +Q +
Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
Query: 208 EEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLK 261
E +K R E++ +++E +Q+ E Q ++ Q K + E++ E++ K
Sbjct: 526 REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Score = 65.5 bits (158), Expect = 6e-11
Identities = 49/238 (20%), Positives = 124/238 (52%), Gaps = 14/238 (5%)
Query: 30 KNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTR 89
+ +M E+KIR LE++ E ++ +Q +++ K + K E + K+ E + +
Sbjct: 369 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 428
Query: 90 EKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLAN 149
E+ ++++K RQ E +++ R+ +R+E+E+ EE +++E+ ++ + K +
Sbjct: 429 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE--KIREQEEIWRQKEKMHE 486
Query: 150 KEK-EHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE--MRTEMEVLKQQVQI 206
+EK E ++ R + + D E+ +R+ + +E +R + E +++Q +
Sbjct: 487 QEKIRKQEEKVWRQEEKMHD--------QEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 207 YEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
E + + E++ +++E++Q+ E + Q ++ Q + + +KEK+ +Q ++++
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 595
Score = 65.5 bits (158), Expect = 6e-11
Identities = 51/236 (21%), Positives = 129/236 (54%), Gaps = 11/236 (4%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKEL-YERKVAELKTKLDAAERFLSTREKDPHQ 95
++KIR E++R+E ++ +Q +Q + K E K+ E + K+ E+ + +E+ H+
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 448
Query: 96 RQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHEL----KEENKLLKGKNTLANKE 151
+++ + ++ +++ ++ RE++E R E++HE K+E K+ + + + ++E
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE 508
Query: 152 KEHYECEIK--RLNKALQDALNIKCSFSEDCLRKSR--VEFCHEEMRTEMEVLKQQVQIY 207
++ E E K R + +++ K E+ +R+ ++ E+M + E +++Q ++
Sbjct: 509 EKIREQEEKMWRQEEKIREQEE-KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
Query: 208 EEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
++ +K R E++ ++KE++++ E Q ++ Q + Q ++EK+ +Q ++M
Sbjct: 568 RQE-EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622
Score = 55.5 bits (132), Expect = 6e-08
Identities = 47/254 (18%), Positives = 128/254 (50%), Gaps = 20/254 (7%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYER-KVA 73
E ++ A+ ++ + E+KIR EK + W Q+ ++++E+ K+
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEK---------KMWRQE----EKIHEQEKIR 453
Query: 74 ELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHE 133
E + + + E + R+++ + Q + RQ+E +++ R + ++ +++E+++++ +
Sbjct: 454 EEEKRQEQEEMW---RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Query: 134 LKE-ENKLLKGKNTLANKEKEHYECE--IKRLNKALQDALNIKCSFSEDCLRKSRVEFCH 190
++E E K+ + + + +E++ E E I+ + +Q+ E + ++
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE 570
Query: 191 EEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQ 250
E++R + E +++Q + E +K E++ +++E +Q+ E Q ++ Q + Q
Sbjct: 571 EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630
Query: 251 MEKEKLEKQLKQMY 264
++EK+ +Q ++M+
Sbjct: 631 EQEEKMRRQEEKMW 644
Score = 52.4 bits (124), Expect = 6e-07
Identities = 54/252 (21%), Positives = 114/252 (45%), Gaps = 16/252 (6%)
Query: 17 STEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELK 76
S E ++ A ++ L LE ++ + + E+ ++K+L E + +L
Sbjct: 106 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQL-EGEARDLI 164
Query: 77 TKLDAAERFLSTREKD----PHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELH 132
++L + +F E+ Q+++ D E ++RD L R E
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE------- 217
Query: 133 ELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE 192
ELKE+N L+ K L EK + +K L + L+ A K + L ++ + +E
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA---KLLLPQQQL-QAEADHLGKE 273
Query: 193 MRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQME 252
+++ L+ QV+ E + + E++ +++E++Q+ E Q Q ++ Q + + +
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
Query: 253 KEKLEKQLKQMY 264
+EK+ +Q + M+
Sbjct: 334 EEKMRRQEEMMW 345
Score = 52.4 bits (124), Expect = 6e-07
Identities = 54/257 (21%), Positives = 116/257 (45%), Gaps = 17/257 (6%)
Query: 10 RMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELL----EVNQQWDQQFRSMK 65
+ + AE+ KE S + + L +Q++E + E Q+W+++ + +
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 66 ELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKE 125
E K+ E + K+ E + +E+ +++ K RQ E +++ RL+ EKE
Sbjct: 321 E----KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376
Query: 126 RLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSR 185
EL E E + ++ + +E++ E E ++ +A K E+ +R+
Sbjct: 377 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 186 VEFCHEEMRTEMEVLKQQVQIYEEDFKKERSD---RERLNQEKEELQQINETSQSQLNRL 242
+ +E E + +Q +I EE+ ++E+ + +E +E+EE+ + E Q ++
Sbjct: 437 KKMWRQE-----EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ-EKI 490
Query: 243 NSQIKACQMEKEKLEKQ 259
Q + ++EK+ Q
Sbjct: 491 RKQEEKVWRQEEKMHDQ 507
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 66.2 bits (160), Expect = 4e-11
Identities = 54/244 (22%), Positives = 126/244 (51%), Gaps = 32/244 (13%)
Query: 44 EKQRKELLEVNQQWDQQFRSMKELYER--KVAELKTKLDAAERFLSTREKDPHQRQRKDD 101
EK ++ L++ +Q ++ +R ++++E+ K+ E + K+ E + +E+ +++ K
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 102 RQREDDRQRDLTRDRLQREEKEKERLNEELHELKE---------ENKLLKGKNTLANKEK 152
RQ E R++D +++Q +E+E R E++ E +E E K+ + + +E+
Sbjct: 371 RQEEKIREQD---EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEE 427
Query: 153 EHYECE--IKRLNKALQDALNI-------------KCSFSEDCLRKSRVEFCHEEMRT-- 195
E + E I+ L + +QD K E+ +++ + +E +T
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR 487
Query: 196 EMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEK 255
+ ++LKQ+ +I+E++ K R + E++ +++E++Q+ E Q Q ++ Q ++EK
Sbjct: 488 QEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK 546
Query: 256 LEKQ 259
+++Q
Sbjct: 547 MQEQ 550
Score = 57.4 bits (137), Expect = 2e-08
Identities = 48/238 (20%), Positives = 124/238 (52%), Gaps = 15/238 (6%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY---ERKVAELKTKLDAAERFLSTR 89
+ S+ K++ ++ + +NQQ +++ +E E K+ E + K+ E + +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 90 EKDPHQRQRKDDRQREDD--RQRDLTRDRLQREEKEKERLNEELHELKEEN-KLLKGKNT 146
E+ H+++ K R++ED RQ + R++ ++ +++E++ + +++E++ K+ + +
Sbjct: 331 EEKMHEQEEKI-REQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEE 389
Query: 147 LANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQI 206
+ +E++ E E KR K + ++ + ++ EEM + E +++ ++
Sbjct: 390 MWRQEEKIREQEEKRQEKMWRQEKKMR-------EQDEKIREQEEEMWRQEEKIRELEEM 442
Query: 207 YEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
++ +K R E++ +E+E++Q+ E Q Q ++ Q + +EKL KQ ++++
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ-EEKTWRQEKLLKQEEKIW 499
Score = 48.5 bits (114), Expect = 8e-06
Identities = 43/199 (21%), Positives = 101/199 (50%), Gaps = 14/199 (7%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
E+KIR +++ +E E + +++ R +E + K+ + K+ RE+D R
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM---------REQDEKIR 423
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYE 156
+++++ R++++ R+L +EEK +E + E++ E EE K+ + + + +E++ E
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLRE-VEEKMQE--EEEKMQEQEEKIQRQEEKIQE 480
Query: 157 CEIK--RLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKE 214
E K R K L+ I + ++ ++ E+M+ + E +++Q + E +
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 215 RSDRERLNQEKEELQQINE 233
E++ +++ LQ++ E
Sbjct: 541 WQQEEKMQEQEVRLQELEE 559
Score = 39.3 bits (90), Expect = 0.005
Identities = 28/115 (24%), Positives = 62/115 (53%), Gaps = 9/115 (7%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKD 92
M E+KI ++Q +++ E ++ +Q + +K+ E K+ E + K+ E + +E+
Sbjct: 464 MQEQEEKI---QRQEEKIQEQEEKTWRQEKLLKQ--EEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 93 PHQRQRKDDRQREDDRQRDL----TRDRLQREEKEKERLNEELHELKEENKLLKG 143
+++ K RQ E R++++ +++Q +E + L E L +L ++ +LL G
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573
Score = 38.5 bits (88), Expect = 0.008
Identities = 38/179 (21%), Positives = 81/179 (45%), Gaps = 31/179 (17%)
Query: 117 LQREEKEKERLNEELH-------ELKEENKLLKGKNTLANKEKEHYECEIK--------- 160
+++ KE++ + EL+ ELKE+N L+ K L EK + +K
Sbjct: 192 IEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 161 --------------RLNKALQD-ALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQ 205
RL K LQ + ++ E+ L + E+M + E +++Q +
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 206 IYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
E K R E++ +++E++ + E + Q +++ Q + + ++EK+ +Q ++M+
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 66.2 bits (160), Expect = 4e-11
Identities = 54/244 (22%), Positives = 126/244 (51%), Gaps = 32/244 (13%)
Query: 44 EKQRKELLEVNQQWDQQFRSMKELYER--KVAELKTKLDAAERFLSTREKDPHQRQRKDD 101
EK ++ L++ +Q ++ +R ++++E+ K+ E + K+ E + +E+ +++ K
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 102 RQREDDRQRDLTRDRLQREEKEKERLNEELHELKE---------ENKLLKGKNTLANKEK 152
RQ E R++D +++Q +E+E R E++ E +E E K+ + + +E+
Sbjct: 371 RQEEKIREQD---EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEE 427
Query: 153 EHYECE--IKRLNKALQDALNI-------------KCSFSEDCLRKSRVEFCHEEMRT-- 195
E + E I+ L + +QD K E+ +++ + +E +T
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR 487
Query: 196 EMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEK 255
+ ++LKQ+ +I+E++ K R + E++ +++E++Q+ E Q Q ++ Q ++EK
Sbjct: 488 QEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK 546
Query: 256 LEKQ 259
+++Q
Sbjct: 547 MQEQ 550
Score = 57.4 bits (137), Expect = 2e-08
Identities = 48/238 (20%), Positives = 124/238 (52%), Gaps = 15/238 (6%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY---ERKVAELKTKLDAAERFLSTR 89
+ S+ K++ ++ + +NQQ +++ +E E K+ E + K+ E + +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 90 EKDPHQRQRKDDRQREDD--RQRDLTRDRLQREEKEKERLNEELHELKEEN-KLLKGKNT 146
E+ H+++ K R++ED RQ + R++ ++ +++E++ + +++E++ K+ + +
Sbjct: 331 EEKMHEQEEKI-REQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEE 389
Query: 147 LANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQI 206
+ +E++ E E KR K + ++ + ++ EEM + E +++ ++
Sbjct: 390 MWRQEEKIREQEEKRQEKMWRQEKKMR-------EQDEKIREQEEEMWRQEEKIRELEEM 442
Query: 207 YEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
++ +K R E++ +E+E++Q+ E Q Q ++ Q + +EKL KQ ++++
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ-EEKTWRQEKLLKQEEKIW 499
Score = 48.5 bits (114), Expect = 8e-06
Identities = 43/199 (21%), Positives = 101/199 (50%), Gaps = 14/199 (7%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
E+KIR +++ +E E + +++ R +E + K+ + K+ RE+D R
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM---------REQDEKIR 423
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYE 156
+++++ R++++ R+L +EEK +E + E++ E EE K+ + + + +E++ E
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLRE-VEEKMQE--EEEKMQEQEEKIQRQEEKIQE 480
Query: 157 CEIK--RLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKE 214
E K R K L+ I + ++ ++ E+M+ + E +++Q + E +
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 215 RSDRERLNQEKEELQQINE 233
E++ +++ LQ++ E
Sbjct: 541 WQQEEKMQEQEVRLQELEE 559
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 31/179 (17%)
Query: 117 LQREEKEKERLNEELH-------ELKEENKLLKGKNTLANKEKEHYECEIK--------- 160
+++ KE++ L+ EL+ ELKE+N L+ K L EK + +K
Sbjct: 192 IEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 161 --------------RLNKALQD-ALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQ 205
RL K LQ + ++ E+ L + E+M + E +++Q +
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 206 IYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
E K R E++ +++E++ + E + Q +++ Q + + ++EK+ +Q ++M+
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Score = 39.3 bits (90), Expect = 0.005
Identities = 28/115 (24%), Positives = 62/115 (53%), Gaps = 9/115 (7%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKD 92
M E+KI ++Q +++ E ++ +Q + +K+ E K+ E + K+ E + +E+
Sbjct: 464 MQEQEEKI---QRQEEKIQEQEEKTWRQEKLLKQ--EEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 93 PHQRQRKDDRQREDDRQRDL----TRDRLQREEKEKERLNEELHELKEENKLLKG 143
+++ K RQ E R++++ +++Q +E + L E L +L ++ +LL G
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 65.1 bits (157), Expect = 8e-11
Identities = 52/233 (22%), Positives = 122/233 (52%), Gaps = 6/233 (2%)
Query: 29 RKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLST 88
++ +M E+KIR LE++ E ++ +Q +++ K + K E + K+ E +
Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 441
Query: 89 REKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLA 148
+E+ ++++K RQ E +++ R+ +R+E+E+ EE ++ E+ ++ + K +
Sbjct: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE--KIHEQEEIWRQKEKMH 499
Query: 149 NKEKE--HYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQI 206
+E++ E ++ R + +++ E R+ EEM E E + +Q +I
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Query: 207 YEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQ 259
+EE+ ++E+ D ++ +++E++++ E Q ++ Q + Q ++EK+ KQ
Sbjct: 560 WEEEKRQEQED--KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Score = 60.1 bits (144), Expect = 3e-09
Identities = 57/282 (20%), Positives = 142/282 (50%), Gaps = 37/282 (13%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQ--------------RKELLEVNQQWDQQ 60
E ++ A+ ++ + E+KIR EK+ R+E E Q+ ++
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE--EKRQEQEEM 478
Query: 61 FRSMKELYER--------KVAELKTKLDAAERFL-----STREKDPHQRQRKDDRQREDD 107
+R ++++E+ K+ E + K+ E + RE++ R++++ R+++
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE 538
Query: 108 RQRDLTRDRLQREEK---EKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIK-RLN 163
+ R+ ++ + REE+ E+E++ EE ++E+K+ + + + +E++ + E K R
Sbjct: 539 KIRE--QEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ 596
Query: 164 KALQDALNIKCSFSEDCLR--KSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERL 221
+ + K E+ +R + +++ E++R + E +++Q ++ +E +K E++
Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656
Query: 222 NQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
+++E++Q+ ET Q ++ Q K + ++EK+ +Q + M
Sbjct: 657 CEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Score = 57.8 bits (138), Expect = 1e-08
Identities = 55/245 (22%), Positives = 123/245 (50%), Gaps = 22/245 (8%)
Query: 29 RKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLST 88
+K M+ E+KIR KQ +++ ++ +Q ++E E K+ + K+ E
Sbjct: 494 QKEKMHEQEEKIR---KQEEKVWRQEEKIREQEEKIRE-QEEKMWRQEEKIREQEEMWRE 549
Query: 89 REKDPHQRQ--RKDDRQREDD---RQRDLTRDRLQREEKEKERLNEELHELKE-ENKLLK 142
EK Q + ++ RQ ++D RQ + R++ ++ +++E++ E+ + +E E K+ K
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 143 GKNTLANKEKEHYECE--IKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE--MRTEME 198
+ + +E++ E E I+ + +++ + E+ + + + C +E M+ + E
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE-QEEKMGEQEEKMCEQEEKMQEQEE 668
Query: 199 VLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEK 258
+ +Q + E KK R E++ +++E +Q+ E Q + K C+ E EK+++
Sbjct: 669 TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ------EEKMCEQE-EKMQE 721
Query: 259 QLKQM 263
Q ++M
Sbjct: 722 QEEKM 726
Score = 55.1 bits (131), Expect = 8e-08
Identities = 53/279 (18%), Positives = 129/279 (46%), Gaps = 29/279 (10%)
Query: 10 RMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELL----EVNQQWDQQFRSMK 65
+ + AE+ KE S + + L +Q++E + E Q+W+++ + +
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 66 ELY---ERKVAELKTKLDAAERFLSTREKDPHQRQR----KDDRQREDDRQRDLTRDRLQ 118
E E K+ E + K+ E + +E+ +++ K+++ R + ++++
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
Query: 119 REEK---EKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCS 175
R+E+ EKE EL E E + ++ + +E++ E E ++ +A K
Sbjct: 381 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 440
Query: 176 FSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSD----------RERLNQEK 225
E+ +R+ + +E E + +Q +I EE+ ++E+ + +E + ++K
Sbjct: 441 EQEEKIREQEKKMWRQE-----EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 226 EELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
E++ + E + Q ++ Q + + ++EK+ +Q ++M+
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Score = 52.4 bits (124), Expect = 6e-07
Identities = 54/252 (21%), Positives = 114/252 (45%), Gaps = 16/252 (6%)
Query: 17 STEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELK 76
S E ++ A ++ L LE ++ + + E+ ++K+L E + +L
Sbjct: 106 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQL-EGEARDLI 164
Query: 77 TKLDAAERFLSTREKD----PHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELH 132
++L + +F E+ Q+++ D E ++RD L R E
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE------- 217
Query: 133 ELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE 192
ELKE+N L+ K L EK + +K L + L+ A K + L ++ + +E
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA---KLLLPQQQL-QAEADHLGKE 273
Query: 193 MRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQME 252
+++ L+ QV+ E + + E++ +++E++Q+ E Q Q ++ Q + + +
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
Query: 253 KEKLEKQLKQMY 264
+EK+ +Q + M+
Sbjct: 334 EEKMRRQEEMMW 345
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/170 (21%), Positives = 80/170 (47%), Gaps = 14/170 (8%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELY---ERKVAELKTKLDAAERFLSTREKDP 93
E+KIR E++R+E E + +++ R +E E K+ E + K+ E +E+
Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 94 HQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKE 153
+++ K Q E ++++ T R + + +E+E+ E +E K+ + + + +E++
Sbjct: 650 GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE-----QEEKIREQEEMMQEQEEK 704
Query: 154 HYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQ 203
+E E K + K E+ +R+ + +E+R + K Q
Sbjct: 705 MWEQEEKMCEQ------EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 41.6 bits (96), Expect = 0.001
Identities = 51/225 (22%), Positives = 112/225 (49%), Gaps = 28/225 (12%)
Query: 46 QRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERF--LSTREKDPHQRQRKDDRQ 103
+R +LL QQ + + + + A+L+ +++ E + L+ ++++ RQ + ++
Sbjct: 252 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 104 REDDRQRDLTRDRLQ----REEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEI 159
E+ Q + R Q RE++EK R EE+ KEE K+ + + + KE++ +
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KMRRQEEMMWEKEEK-----M 365
Query: 160 KRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRE 219
+R + + + E+ +R+ EEM E E ++++ + +K R E
Sbjct: 366 RRQEEMMWE--------KEEKMRRQ------EEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 220 RLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
+ QE+E++++ E Q Q ++ Q + + ++EK+ +Q K+M+
Sbjct: 412 K-RQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/241 (21%), Positives = 121/241 (50%), Gaps = 24/241 (9%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMK--ELYERKVAELKTKLDAAERFLSTREKDPH 94
EQ+ + E++ K + + WDQ+ R + E K ++ + ++ RE+
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 95 QRQRK-----DDRQREDDRQRDLTRDRLQREEKE-----KERLNEELHELKE-ENKLLKG 143
Q Q K +++ RE++R R+ R++ REE+E +E++ E+ +++E E K+ +
Sbjct: 543 QEQEKKTWDQEEKMREEERMRE--REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 144 KNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQ 203
+ + +E++ +E E K + +D K E+ + + E+M+ + E + +Q
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEED----KMQEQEEMMWEQ-----EEKMQEQEEKMWEQ 651
Query: 204 VQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
+ E +K R E++ ++E++++ E Q Q ++ Q + + ++EK+ Q ++M
Sbjct: 652 EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
Query: 264 Y 264
+
Sbjct: 712 W 712
Score = 61.6 bits (148), Expect = 9e-10
Identities = 67/293 (22%), Positives = 136/293 (46%), Gaps = 38/293 (12%)
Query: 3 HFVQGTSRMIAAESSTEHKEC---AEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQ 59
HF R ++A S T HK+ E T++ SLE + + EL + N + +
Sbjct: 138 HFAGELQRALSAVS-TWHKKADRYIEELTKERDALSLELYRNTITNE--ELKKKNAELQE 194
Query: 60 QFR---SMKELYERKVAELKTKLDAAERFL-----------------STREKDPHQRQRK 99
+ R S K + V ELK KL+ A+ L RE++ R+++
Sbjct: 195 KLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 254
Query: 100 DDRQREDDRQRDLTRDRLQREEK---EKERLNEELHELKEENKLLKGKNTLANKEKEHYE 156
+ R+++R R+ ++EEK +++RL E+ EL+E+ K L+ + L +E++ E
Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314
Query: 157 CEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERS 216
E K + ++ + ++ R+ ++MR + + ++ Q + E ++ R
Sbjct: 315 QE----EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 370
Query: 217 DRERLNQ-----EKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
ER+ + E+EE Q E + + ++ + + + ++EK++KQ + M+
Sbjct: 371 KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/242 (20%), Positives = 121/242 (50%), Gaps = 12/242 (4%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERK--VAELKTKL-DAAERFLSTR 89
M E+K+R EK+ +E + ++ +++ R K+L E++ + E + K+ + E+
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 90 EKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLAN 149
EK Q +R +++++ Q RD+ +R ++ ERL E+ ++E+ K+ + + +
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE 390
Query: 150 KEK-EHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYE 208
+E+ E +++ + +++ E+ + E+ + + + E L +Q ++ E
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 209 EDFK------KERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
++ K K R E QEK+ +Q E + Q +++ Q + + +++K+ Q ++
Sbjct: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQ--EKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Query: 263 MY 264
M+
Sbjct: 509 MW 510
Score = 56.2 bits (134), Expect = 4e-08
Identities = 52/252 (20%), Positives = 125/252 (49%), Gaps = 22/252 (8%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAE 74
E +E E + M E+K+R +++K + + WDQ+ + M+E E ++ E
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMR---EEKKTQEQEKKTWDQEEK-MRE--EERMRE 564
Query: 75 LKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHEL 134
+ K+ E + +E+ + Q ++++ RE + + +++Q +E++ E++ E
Sbjct: 565 REKKMREEEEMMREQEE---KMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Query: 135 KEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLR--KSRVEFCHEE 192
+EE+K+ + + + +E++ E E K + K E+ +R + +++ E+
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ------EEKMREQEEKMREQEEKMQGQEEK 675
Query: 193 MRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEEL--QQINETSQSQLNRLNSQIKACQ 250
MR + E ++ Q + E +K R E++ ++E++ Q+ Q ++ +I+
Sbjct: 676 MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD-- 733
Query: 251 MEKEKLEKQLKQ 262
+KEK++++L +
Sbjct: 734 -QKEKMQERLPE 744
Score = 54.7 bits (130), Expect = 1e-07
Identities = 51/238 (21%), Positives = 121/238 (50%), Gaps = 18/238 (7%)
Query: 34 NSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDP 93
N+L+++ + +Q +EL E ++ +Q M E ++ E + K+ E + +EK
Sbjct: 230 NTLQEE---MWRQEEELREQEKKIRKQEEKMWR-QEERLREQEGKMREQEEKMRRQEKRL 285
Query: 94 HQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKE-ENKLLKGKNTLANKEK 152
+++++ Q ++ R++ R++ ++ ++++E++ E+ +++E E K+ + + L +EK
Sbjct: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345
Query: 153 EHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFK 212
+ E E K ++ + ++ LR+ +E E E Q+ + E K
Sbjct: 346 QMREQEQKMRDQ------EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Query: 213 KERSDRERLNQEKEELQQINET------SQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
K R + E + +++E++Q+ E + Q RL Q K E+EK+++Q ++++
Sbjct: 400 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ-KEKLWEQEKMQEQEEKIW 456
Score = 53.9 bits (128), Expect = 2e-07
Identities = 46/232 (19%), Positives = 106/232 (45%), Gaps = 8/232 (3%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKL-DAAERFLSTREKDPHQ 95
EQ+ + E++ K + + W Q+ R ++ E+++ E + K+ D ER E+ +
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQ--EKQMREQEQKMRDQEERMWEQDERLREK 371
Query: 96 RQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHY 155
+R ++++ +++ + + RE ++K R EE +EE + +N +EKE
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 431
Query: 156 ECEIKRLNKALQDALNI-----KCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEED 210
+ + + L + + K E+ +R + E+ E +++Q E
Sbjct: 432 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 491
Query: 211 FKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
+K R +++ ++E + + +E + + R+ Q K Q E++ E++ Q
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Score = 50.8 bits (120), Expect = 2e-06
Identities = 49/241 (20%), Positives = 109/241 (45%), Gaps = 24/241 (9%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
EQ+ + E++ K + + W+Q+ + M+E ++ + + + ER E+ Q
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQE-KQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEEN------------KLLKGK 144
+ + ++ + +R R++ REE+E R EE + +EEN +L + K
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 439
Query: 145 NTLANKEK-EHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQ 203
L +EK + E +I + ++D E+ + + + E+MR + + + +Q
Sbjct: 440 EKLWEQEKMQEQEEKIWEQEEKIRD--------QEEMWGQEKKMWRQEKMREQEDQMWEQ 491
Query: 204 VQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
+ + +K ER+ ++ E L++ E + Q + K E++K ++Q K+
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK--MREEKKTQEQEKKT 549
Query: 264 Y 264
+
Sbjct: 550 W 550
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/247 (20%), Positives = 113/247 (45%), Gaps = 13/247 (5%)
Query: 19 EHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTK 78
E K E R+ E++ E++ K + W+Q+ KE ++++ E K K
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE---EKEWQQQRLPEQKEK 441
Query: 79 LDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEEN 138
L E+ EK Q ++ D++ +++ + R RE++++ ++E
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM--------WEQEE 493
Query: 139 KLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEME 198
K+ + + ++E+ +E + + K + K E+ +R+ + E+ + E
Sbjct: 494 KMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQE 553
Query: 199 VLKQQVQIYEEDFKKERSDRERLNQEKEE-LQQINETSQSQLNRLNSQIKACQMEKEKLE 257
++ + E KK R + E + +E+EE +Q+ E + Q ++ Q + Q ++EK+
Sbjct: 554 EKMREEERMREREKKMREEEEMM-REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Query: 258 KQLKQMY 264
+Q ++M+
Sbjct: 613 EQEEKMW 619
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 62.4 bits (150), Expect = 5e-10
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 33/266 (12%)
Query: 7 GTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCL--EKQRKELLEVNQQWDQQFRSM 64
G+ + + +S + + EP ++ LE+K+ +K+R+ N + +++ +++
Sbjct: 314 GSGISVISSTSVDQRLPEEP-VLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQAL 372
Query: 65 KELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEK 124
E +RK E +L+ AE+ RE+ +R+R+ + +++ ++QR+L R R + KE
Sbjct: 373 LE-QQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEI 431
Query: 125 ERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKS 184
ER EL+ + +L E+ + + + NK +D + +K +K
Sbjct: 432 ERREAAKRELERQRQL--------EWERNRRQELLNQRNKEQEDIVVLKA-------KKK 476
Query: 185 RVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKE-------ELQQINETSQS 237
+EF E + + L+ ++Q +R + E N+ +E LQQ + SQ
Sbjct: 477 TLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQ 536
Query: 238 QLNRLNSQIKACQMEKEKLEKQLKQM 263
L RL EK+ L QLKQ+
Sbjct: 537 MLGRLIP-------EKQILNDQLKQV 555
Score = 49.7 bits (117), Expect = 4e-06
Identities = 51/252 (20%), Positives = 120/252 (47%), Gaps = 37/252 (14%)
Query: 44 EKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQ 103
E++RK LE+ +Q ++Q ++ E + E++ + +AA+R L + + +R R+ +
Sbjct: 400 EQERKRQLELEKQLEKQRELERQREEERRKEIERR-EAAKRELERQRQLEWERNRRQELL 458
Query: 104 REDDRQRD---LTRDRLQREEKEKERLNEELHELKEENKLLKGKNTL-------ANKEKE 153
+ +++++ + + + + E E E LN++ H+L+ + + ++ + T NK +E
Sbjct: 459 NQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRE 518
Query: 154 HYECEIKRLNKALQDALNI------KCSFSEDCLRKSRVEFCHEE----MRTEMEV---- 199
EI L + LQ++ + + D L++ + H + ++ +E
Sbjct: 519 LRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELA 578
Query: 200 ---LKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQ---------LNRLNSQIK 247
L+ Q+ E++ + + + + N + +EL++I+ Q Q L + + K
Sbjct: 579 RQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERK 638
Query: 248 ACQMEKEKLEKQ 259
++EK+K E Q
Sbjct: 639 IIELEKQKEEAQ 650
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/143 (23%), Positives = 78/143 (54%), Gaps = 13/143 (9%)
Query: 11 MIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYER 70
++ + + E KE A R++L + L++ +EK+ + L+ ++ Q + ++E++ +
Sbjct: 565 LVTLKRALEAKELA----RQHLRDQLDE----VEKETRSKLQEIDIFNNQLKELREIHNK 616
Query: 71 KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
+ + K K AER ++K+ ++ + ++Q+E+ ++R RD+ E ++E ++
Sbjct: 617 QQLQ-KQKSMEAERL---KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQR 672
Query: 131 LHELKEENKLLKGKNTLANKEKE 153
+L EE K LK + ++ K+ E
Sbjct: 673 PRKLHEEEK-LKREESVKKKDGE 694
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 62.4 bits (150), Expect = 5e-10
Identities = 63/266 (23%), Positives = 123/266 (46%), Gaps = 33/266 (12%)
Query: 7 GTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCL--EKQRKELLEVNQQWDQQFRSM 64
G+ + + +S + + EP ++ LE+K+ +K+R+ N + +++ +++
Sbjct: 314 GSGISVISSTSVDQRLPEEP-VLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQAL 372
Query: 65 KELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEK 124
E +RK E +L+ AE+ RE+ +R+R+ + +++ ++QR+L R R + KE
Sbjct: 373 LE-QQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEI 431
Query: 125 ERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKS 184
ER EL+ + +L E+ + + + NK +D + +K +K
Sbjct: 432 ERREAAKRELERQRQL--------EWERNRRQELLNQRNKEQEDIVVLKA-------KKK 476
Query: 185 RVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKE-------ELQQINETSQS 237
+EF E + + L+ ++Q +R + E N+ +E LQQ + SQ
Sbjct: 477 TLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQ 536
Query: 238 QLNRLNSQIKACQMEKEKLEKQLKQM 263
L RL EK+ L QLKQ+
Sbjct: 537 MLGRLIP-------EKQILNDQLKQV 555
Score = 49.7 bits (117), Expect = 4e-06
Identities = 51/252 (20%), Positives = 120/252 (47%), Gaps = 37/252 (14%)
Query: 44 EKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQ 103
E++RK LE+ +Q ++Q ++ E + E++ + +AA+R L + + +R R+ +
Sbjct: 400 EQERKRQLELEKQLEKQRELERQREEERRKEIERR-EAAKRELERQRQLEWERNRRQELL 458
Query: 104 REDDRQRD---LTRDRLQREEKEKERLNEELHELKEENKLLKGKNTL-------ANKEKE 153
+ +++++ + + + + E E E LN++ H+L+ + + ++ + T NK +E
Sbjct: 459 NQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRE 518
Query: 154 HYECEIKRLNKALQDALNI------KCSFSEDCLRKSRVEFCHEE----MRTEMEV---- 199
EI L + LQ++ + + D L++ + H + ++ +E
Sbjct: 519 LRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELA 578
Query: 200 ---LKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQ---------LNRLNSQIK 247
L+ Q+ E++ + + + + N + +EL++I+ Q Q L + + K
Sbjct: 579 RQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERK 638
Query: 248 ACQMEKEKLEKQ 259
++EK+K E Q
Sbjct: 639 IIELEKQKEEAQ 650
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/143 (23%), Positives = 78/143 (54%), Gaps = 13/143 (9%)
Query: 11 MIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYER 70
++ + + E KE A R++L + L++ +EK+ + L+ ++ Q + ++E++ +
Sbjct: 565 LVTLKRALEAKELA----RQHLRDQLDE----VEKETRSKLQEIDIFNNQLKELREIHNK 616
Query: 71 KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
+ + K K AER ++K+ ++ + ++Q+E+ ++R RD+ E ++E ++
Sbjct: 617 QQLQ-KQKSMEAERL---KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQR 672
Query: 131 LHELKEENKLLKGKNTLANKEKE 153
+L EE K LK + ++ K+ E
Sbjct: 673 PRKLHEEEK-LKREESVKKKDGE 694
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 62.4 bits (150), Expect = 5e-10
Identities = 61/272 (22%), Positives = 121/272 (44%), Gaps = 23/272 (8%)
Query: 2 AHFVQGTSRMIAAESS----TEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQ- 56
A + Q +++ A E TE C + ++ SLEQKI+ EK+ +E L Q+
Sbjct: 348 AQYDQASTKYTALEQKLKKLTEDLSCQRQNA-ESARCSLEQKIKEKEKEFQEELSRQQRS 406
Query: 57 ---WDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLT 113
DQ+ MK +++ + K + + L +K +Q+ ++ E ++
Sbjct: 407 FQTLDQECIQMKARLTQELQQAKNMHNVLQAEL---DKLTSVKQQLENNLEEFKQKLCRA 463
Query: 114 RDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNI- 172
Q + ++ L + E+K+EN LLK + +E H E E+K + + L + N
Sbjct: 464 EQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFA 523
Query: 173 -----KCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERS-DRERLNQEKE 226
K + E LR + + +E +E LK V D +K+R ++ L + +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAV----ADLEKQRDCSQDLLKKREH 579
Query: 227 ELQQINETSQSQLNRLNSQIKACQMEKEKLEK 258
++Q+N+ + + A +++K++ E+
Sbjct: 580 HIEQLNDKLSKTEKESKALLSALELKKKEYEE 611
Score = 59.3 bits (142), Expect = 4e-09
Identities = 67/233 (28%), Positives = 112/233 (48%), Gaps = 40/233 (17%)
Query: 36 LEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERK------VAELKTKLDAAERFLSTR 89
LE +I L K+ KELL V + Q R + YE+ A L K + A R ST+
Sbjct: 2054 LENQIAQLNKE-KELL-VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQ 2111
Query: 90 EKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLAN 149
E + HQ +R ++ R R++ +EK++ + E+L E + EN LK K + N
Sbjct: 2112 E-EVHQLRRGIEKLRV----------RIEADEKKQLHIAEKLKERERENDSLKDK--VEN 2158
Query: 150 KEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEE 209
E+E E + + DA N K E ++T++E + + ++++E
Sbjct: 2159 LERELQMSE-ENQELVILDAENSKAEV--------------ETLKTQIEEMARSLKVFEL 2203
Query: 210 DFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
D RS++E L ++ +E Q S+L++L S K+ EKE+ E Q+K+
Sbjct: 2204 DLVTLRSEKENLTKQIQEKQ----GQLSELDKLLSSFKSLLEEKEQAEIQIKE 2252
Score = 59.3 bits (142), Expect = 4e-09
Identities = 71/260 (27%), Positives = 121/260 (46%), Gaps = 51/260 (19%)
Query: 27 STRKNLMNSLE----QKIRCLEKQRKELLEVNQQWDQQFRSMKELYE--RKVAELKTKLD 80
S+ KNL N LE K+ +EK VN+ ++ +E++E +K AEL+ +L
Sbjct: 2588 SSYKNLENELELTKMDKMSFVEK-------VNKMTAKETELQREMHEMAQKTAELQEELS 2640
Query: 81 ------AAERFLSTREKDPHQRQRKDDRQREDDRQRDLT---RDRLQREEKEKERLNE-- 129
A E L E + Q K+ + ++ L +D++++E K +E + E
Sbjct: 2641 GEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQ 2700
Query: 130 -ELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEF 188
LHE +++++ L L + K+ YE EI+ + K + E+CL ++E
Sbjct: 2701 LRLHEAEKKHQAL-----LLDTNKQ-YEVEIQTYRE--------KLTSKEECLSSQKLEI 2746
Query: 189 -----CHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLN 243
EE+ LK QI EE K + + + +NQ K+E NE +Q ++ L
Sbjct: 2747 DLLKSSKEELNNS---LKATTQILEELKKTKMDNLKYVNQLKKE----NERAQGKMKLLI 2799
Query: 244 SQIKACQMEKEKLEKQLKQM 263
K + EKE L+K+L Q+
Sbjct: 2800 KSCKQLEEEKEILQKELSQL 2819
Score = 51.2 bits (121), Expect = 1e-06
Identities = 56/247 (22%), Positives = 111/247 (44%), Gaps = 53/247 (21%)
Query: 25 EPSTRKNLMNS-LEQKIR--C-LE---KQRKELLEVNQQWDQQFRSMKELYERKVAELKT 77
E NL+ S EQK R C LE K K+ L +Q + ++ ++ E + +L+
Sbjct: 483 EMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQE 542
Query: 78 KLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEE 137
K++ E L+ ++ + ++QRD ++D L++ E E+LN++L + ++E
Sbjct: 543 KINQQENSLTL--------EKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKE 594
Query: 138 NKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEM 197
+K L L KE E E+K ++ C SE +E++ T+M
Sbjct: 595 SKALLSALELKKKEYE----ELK------EEKTLFSCWKSE-----------NEKLLTQM 633
Query: 198 EVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLE 257
E S++E L + L+ +T Q + + N +++ +M++E L
Sbjct: 634 E-----------------SEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLS 676
Query: 258 KQLKQMY 264
+++ ++
Sbjct: 677 VEIRNLH 683
Score = 48.1 bits (113), Expect = 1e-05
Identities = 63/246 (25%), Positives = 110/246 (44%), Gaps = 31/246 (12%)
Query: 27 STRKNLMNSLEQK------IRCLEKQRKELLEVNQQWDQQFRS-MKELYERKVAELKTKL 79
S ++NL +++K + L K LLE +Q + Q + K E +LK
Sbjct: 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Query: 80 DAAERFLSTREKDPHQRQRKDDRQREDDRQR---DLTRDRLQREEKEKERLNEELHELKE 136
+A +E Q D E+ + R + R RL+ +EK++ + ++L E +
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2329
Query: 137 ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTE 196
LLKG+ + N E+ E EI R N+ AL + S E E ++ +
Sbjct: 2330 HADLLKGR--VENLER---ELEIARTNQE-HAALEAENSKGE-----------VETLKAK 2372
Query: 197 MEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKL 256
+E + Q ++ E D RS++E L E ++ Q+ S+L +NS + EKE+
Sbjct: 2373 IEGMTQSLRGLELDVVTIRSEKENLTNELQKEQE----RISELEIINSSFENILQEKEQE 2428
Query: 257 EKQLKQ 262
+ Q+K+
Sbjct: 2429 KVQMKE 2434
Score = 44.7 bits (104), Expect = 1e-04
Identities = 62/274 (22%), Positives = 118/274 (43%), Gaps = 45/274 (16%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQW--DQQF-RSMKELYERK 71
+S E KE AE ++ ++E L+ Q KEL E DQ+ ++ ++ +
Sbjct: 2237 KSLLEEKEQAEIQIKEESKTAVEM----LQNQLKELNEAVAALCGDQEIMKATEQSLDPP 2292
Query: 72 VAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKE--RLNE 129
+ E ++ E+ + E D ++ + +E + DL + R++ E+E E R N+
Sbjct: 2293 IEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQ 2352
Query: 130 ELHELKEEN-----KLLKGKN--------------TLANKEKEHYECEIKRLNKALQDAL 170
E L+ EN + LK K EKE+ E+++ + + +
Sbjct: 2353 EHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELE 2412
Query: 171 NIKCSFSEDCLRKSRVEFCH--EEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEEL 228
I SF E+ L++ E E+ T ME+L+ Q++ LN+ L
Sbjct: 2413 IINSSF-ENILQEKEQEKVQMKEKSSTAMEMLQTQLK--------------ELNERVAAL 2457
Query: 229 QQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
E +++ L+SQ++ ++EK +L + L +
Sbjct: 2458 HNDQEACKAKEQNLSSQVECLELEKAQLLQGLDE 2491
Score = 42.7 bits (99), Expect = 4e-04
Identities = 46/236 (19%), Positives = 106/236 (44%), Gaps = 21/236 (8%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKD 92
+ S +Q L+KQ +EL+++ + ++ +++++ VAE ++ + S
Sbjct: 839 LESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSA---- 894
Query: 93 PHQRQRKDDRQREDDRQRDLT--RDRLQREEKEKERLNEELHELKEENKLLKGKNTLANK 150
HQ + ++++++L D+++ E+ E + L + H L++ K L+ + +
Sbjct: 895 -HQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSL 953
Query: 151 EKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEED 210
EK+ I + +++ L++ E+M ++++
Sbjct: 954 EKKEMSSIISLNKREIEELTQ-----ENGTLKEINASLNQEKMN----LIQKSESFANYI 1004
Query: 211 FKKERSDRERLNQEKEE----LQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
++E+S E +Q K+E LQ+ ET + + L+ + KA Q + KLE L +
Sbjct: 1005 DEREKSISELSDQYKQEKLILLQRCEETGNAYED-LSQKYKAAQEKNSKLECLLNE 1059
Score = 41.6 bits (96), Expect = 0.001
Identities = 56/246 (22%), Positives = 109/246 (44%), Gaps = 23/246 (9%)
Query: 24 AEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMK-ELYER-----KVAELKT 77
A+ +N +N LE +++ EK+ K + Q+ Q K EL E+ K +
Sbjct: 285 AQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELV 344
Query: 78 KLDAAERFLSTREKDPHQRQRKDDRQREDDRQR-DLTRDRLQREEKEKERLNEELHELKE 136
+ A ST+ Q+ +K RQ + R L+++ KEKE+ E +E
Sbjct: 345 RTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEK------EFQE 398
Query: 137 ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTE 196
E L + + + ++E + + RL + LQ A N+ + + + V+ +++
Sbjct: 399 E--LSRQQRSFQTLDQECIQMKA-RLTQELQQAKNMHNVLQAELDKLTSVK---QQLENN 452
Query: 197 MEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKL 256
+E KQ++ E+ F+ + L + EE+++ N +S + ++ C +E E
Sbjct: 453 LEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREV--CHLEAEL- 509
Query: 257 EKQLKQ 262
K +KQ
Sbjct: 510 -KNIKQ 514
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/260 (18%), Positives = 104/260 (40%), Gaps = 29/260 (11%)
Query: 23 CAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAA 82
C + S + LE K++ L + + Q ++ S+++L + K A L T D
Sbjct: 722 CLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQ 781
Query: 83 ERFLS--------------TREKDPHQRQRKDDRQREDDRQRDLTR-----DRLQREEKE 123
L+ E+ +R + R D ++ D L+ +
Sbjct: 782 RSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLES 841
Query: 124 KERLNEELHELKEENKLLKGK--NTLANKEKEH--YECEIKRLNKALQDALNIKCSFSED 179
++++N +L + EE +KG+ L E+ H + E + LQ+ + + +
Sbjct: 842 QKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAE 901
Query: 180 CLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQL 239
L E E+++L +V+ + + ++ + L +ELQ ++ET +
Sbjct: 902 TLSAL------ENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEK 955
Query: 240 NRLNSQIKACQMEKEKLEKQ 259
++S I + E E+L ++
Sbjct: 956 KEMSSIISLNKREIEELTQE 975
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/266 (21%), Positives = 115/266 (43%), Gaps = 26/266 (9%)
Query: 21 KECAEPST--RKNLMNSLEQKIRCLEKQRKEL---LEVNQQWDQQFRSMKELYERKVAEL 75
K C E ++ ++ LE+++ + +R +L L+ + + E + K EL
Sbjct: 1932 KLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQEL 1991
Query: 76 KTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQ--RDLT--RDRLQREEKEKERLNEEL 131
++ + E + ++ D + +D T +++LQ EK+ + L+
Sbjct: 1992 ESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTK 2051
Query: 132 HELKEENKLLKGKNTLANKEKEHY-----ECEIKRLN--KALQDALNIKCSFSEDCLRKS 184
EL+ + L + L KE E E + ++LN KAL+ AL K F+ LR S
Sbjct: 2052 CELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFA---LRLS 2108
Query: 185 RVEFCHEEMRTEMEVLKQQVQIYE-------EDFKKERSDRERLNQEKEELQQINETSQS 237
+ ++R +E L+ +++ E E K+ + + L + E L++ + S+
Sbjct: 2109 STQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEE 2168
Query: 238 QLNRLNSQIKACQMEKEKLEKQLKQM 263
+ + + E E L+ Q+++M
Sbjct: 2169 NQELVILDAENSKAEVETLKTQIEEM 2194
Score = 37.4 bits (85), Expect = 0.018
Identities = 46/244 (18%), Positives = 100/244 (40%), Gaps = 25/244 (10%)
Query: 20 HKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQW----DQQFRSMKELYERKVAEL 75
+K E T++N +L++ L +++ L++ ++ + D++ +S+ EL ++ E
Sbjct: 965 NKREIEELTQEN--GTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQE- 1021
Query: 76 KTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELK 135
KL +R T Q+ Q ++ + L + E K L +
Sbjct: 1022 --KLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFA 1079
Query: 136 EENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRT 195
+E++ K A + ++ E++ + +AL +S + ++
Sbjct: 1080 KEHQEFLTKLAFAEERNQNLMLELETVQQAL----------------RSEMTDNQNNSKS 1123
Query: 196 EMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEK 255
E LKQ++ +E+ K + + L QE E+L ++ +T N + I+ E+E
Sbjct: 1124 EAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERES 1183
Query: 256 LEKQ 259
Q
Sbjct: 1184 ERNQ 1187
Score = 35.4 bits (80), Expect = 0.070
Identities = 52/259 (20%), Positives = 104/259 (40%), Gaps = 32/259 (12%)
Query: 30 KNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVA-------ELKTKLDAA 82
+ L++S Q++ CL RK+ L N+QW Q+ S+ E K+A +L +L+ A
Sbjct: 1585 EQLLSSERQELDCL---RKQYLSENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLELEVA 1641
Query: 83 ERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHEL-----KEE 137
L + D R + E + ++H++ +++
Sbjct: 1642 RLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSETTERTPKHDVHQICDKDAQQD 1701
Query: 138 NKLLKGKNTLANKEKEHYECEIKRL-NKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTE 196
L K T K EC ++ + + K S +C+ S + F
Sbjct: 1702 LNLDIEKITETGAVKPTGECSGEQSPDTNYEPPGEDKTQGSSECI--SELSFSGPNALVP 1759
Query: 197 MEVLKQQVQIYEEDFKKERSDRERLN-----QEKE--------ELQQINETSQSQLNRLN 243
M+ L Q I+ + + + E L ++++ E+++++ Q +L
Sbjct: 1760 MDFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLM 1819
Query: 244 SQIKACQMEKEKLEKQLKQ 262
++I+AC +E EK+ +LK+
Sbjct: 1820 TKIEAC-IELEKIVGELKK 1837
Score = 34.3 bits (77), Expect = 0.16
Identities = 53/231 (22%), Positives = 86/231 (37%), Gaps = 53/231 (22%)
Query: 39 KIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQR 98
K+ CL + L E + + +KE + ++ E TKL AE +R +
Sbjct: 1052 KLECLLNECTSLCENRKN---ELEQLKEAFAKEHQEFLTKLAFAE-----------ERNQ 1097
Query: 99 KDDRQREDDRQ--RDLTRDRLQREEKEKERLNEELHELKEE-NKLLKGKNTLANKEKEHY 155
+ E +Q R D + E L +E+ LKEE NK+ K N L +
Sbjct: 1098 NLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQE----- 1152
Query: 156 ECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKER 215
N+ L + K HE E E ++ V K+
Sbjct: 1153 -------NEQLMKVMKTK----------------HECQNLESEPIRNSV-------KERE 1182
Query: 216 SDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKE-KLEKQLKQMYC 265
S+R + N + + ++ E S N Q++A KE KL++ K+ C
Sbjct: 1183 SERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKEC 1233
Score = 32.0 bits (71), Expect = 0.77
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 24/122 (19%)
Query: 141 LKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVL 200
L+G+ KEK+ + ++ L ALQ +K +VE +TE L
Sbjct: 23 LEGQLDKLKKEKQQRQFQLDSLEAALQK-------------QKQKVE----NEKTEGTNL 65
Query: 201 KQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQL 260
K++ Q E E L + K+++ + +SQ+N Q+ + + + EKLE++L
Sbjct: 66 KRENQRLMEIC-------ESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQEL 118
Query: 261 KQ 262
K+
Sbjct: 119 KR 120
Score = 30.8 bits (68), Expect = 1.7
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 21/114 (18%)
Query: 38 QKIRCLEKQRKELLEVNQQWDQQFRSMKELYER---KVAELKTK-----------LDAAE 83
QKI+ LE Q +L + QQ Q S++ ++ KV KT+ ++ E
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICE 77
Query: 84 RFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEE 137
T++K H+ Q K+ Q + +L +K+ E+L +EL K E
Sbjct: 78 SLEKTKQKISHELQVKES-------QVNFQEGQLNSGKKQIEKLEQELKRCKSE 124
Score = 30.4 bits (67), Expect = 2.2
Identities = 45/239 (18%), Positives = 101/239 (42%), Gaps = 40/239 (16%)
Query: 30 KNLMNSLEQKIRCLE----KQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERF 85
K+ L+Q+I L+ K +KE+ ++ Q+ +Q + MK +E + E +E
Sbjct: 1122 KSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLE-------SEPI 1174
Query: 86 LSTREKDPHQRQRKDDRQREDDRQRDLTRD------------------RLQREEKEKERL 127
++ ++ +R + + + + D ++++ D +LQ EKEKE L
Sbjct: 1175 RNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECL 1234
Query: 128 NEELHELKEENKLLKGKNTLANKEKEHYECEI----------KRLNKALQDALNIKCSFS 177
EL ++ + + ++ + + +CEI L+ + D +++CS
Sbjct: 1235 QHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQ 1294
Query: 178 EDCLRKSRVEFCHEEMRTE-MEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETS 235
+ + +E E ++ E E++ + E R E + + E++ +N+ S
Sbjct: 1295 TTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLNEVKILNDDS 1353
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 62.4 bits (150), Expect = 5e-10
Identities = 64/298 (21%), Positives = 137/298 (45%), Gaps = 36/298 (12%)
Query: 35 SLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPH 94
++++ + L+KQ EL NQQ D + + + + +L+ L +EK+P
Sbjct: 1573 AVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1632
Query: 95 QRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEH 154
++ Q + + + +L R ++Q L EL E+K + +++ +N L E E
Sbjct: 1633 NSALEEREQEKFNLKEELERCKVQSSTLVSS-LEAELSEVKIQTHIVQQENHLLKDELE- 1690
Query: 155 YECEIKRLNKA-----LQDALNIKCSFSEDCLRKSRVEFCHEEMRT------EMEVLKQQ 203
++K+L++ Q ++ S++E L++ E EE+ + + +L+ +
Sbjct: 1691 ---KMKQLHRCPDLSDFQQKISSVLSYNEKLLKEK--EALSEELNSCVDKLAKSSLLEHR 1745
Query: 204 VQIYEEDFK----KERSDRERLNQEKEELQQINETSQS---QLNRLNSQIKACQMEKEKL 256
+ +++ K + S + +L +E++Q + +T Q+ Q++R+ S ++ Q EKE L
Sbjct: 1746 IATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEAL 1805
Query: 257 EKQLKQMYCPPCNCGLVFHLQDPWVP---TGPGAVQKQREHPPDYQWYALDQLPPDVQ 311
++++ ++ N G W P T P + Q++ W LD L + Q
Sbjct: 1806 KQEVMSLHKQLQNAG-----GKSWAPEIATHPSGLHNQQKR---LSWDKLDHLMNEEQ 1855
Score = 51.6 bits (122), Expect = 9e-07
Identities = 53/206 (25%), Positives = 89/206 (43%), Gaps = 37/206 (17%)
Query: 66 ELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKE 125
EL + K+ EL KL L ++KD K++ + +T +Q++ E
Sbjct: 1461 ELEKTKLQELTRKLKERVTIL-VKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKV---E 1516
Query: 126 RLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSR 185
L E +L++EN +L+ + T N+E ++ LN +
Sbjct: 1517 LLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGS-------------------- 1556
Query: 186 VEFCHEEMRTEMEVLKQQ---VQIYEEDFKKERSD----RERLNQEKEELQQINETSQSQ 238
EEM + E +KQ+ VQ E+ KK+ S+ ++L+ E EL Q N +Q +
Sbjct: 1557 ----QEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEK 1612
Query: 239 LNRLNSQI--KACQMEKEKLEKQLKQ 262
L LN ++ CQ EKE L++
Sbjct: 1613 LQELNQRLTEMLCQKEKEPGNSALEE 1638
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/271 (23%), Positives = 128/271 (47%), Gaps = 52/271 (19%)
Query: 1 MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSL--EQKIRCLEKQRKELLEVNQQWD 58
+ H ++ +R+ A++S E + R+ L +S E+K+R L + E+ Q
Sbjct: 727 LQHEMELKARLTQAQASFERE-------REGLQSSAWTEEKVRGLTQ------ELEQFHQ 773
Query: 59 QQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQR---EDDRQRDLTRD 115
+Q S+ E + + EL+ +L + HQR+ ++ R++ E +R+
Sbjct: 774 EQLTSLVEKHTLEKEELRKEL-----------LEKHQRELQEGREKMETECNRRTSQIEA 822
Query: 116 RLQRE-EKEKERLNEELHELKEENKL-LKGKNTLANKEKEHYECEIKRLNKALQDALNIK 173
+ Q + +K ER L L+ + LK +EK +E E +D L +
Sbjct: 823 QFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFE--------KDELTQE 874
Query: 174 CSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERS----DRERLNQEKEELQ 229
C+ +++ L+++ + +T VL Q+ ++ E+ +K+ + +R++L Q+ E+L+
Sbjct: 875 CAEAQELLKETL-----KREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLR 929
Query: 230 QINETSQS----QLNRLNSQIKACQMEKEKL 256
++ET QS Q+ L S K E+E++
Sbjct: 930 NVSETQQSLLSDQILELKSSHKRELREREEV 960
Score = 49.7 bits (117), Expect = 4e-06
Identities = 53/239 (22%), Positives = 105/239 (43%), Gaps = 42/239 (17%)
Query: 36 LEQKIRCLEKQRKELL----EVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREK 91
LE K+R EKQ E + + + Q+ + E+++++LK ++ + + ++
Sbjct: 635 LEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKE 694
Query: 92 DPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKE 151
H+ R E+ +Q + + + +EK RL E+ LK + T A
Sbjct: 695 AHHEATC---RHEEEKKQLQVKLEEEKTHLQEKLRLQHEME--------LKARLTQA--- 740
Query: 152 KEHYECEIKRLNKALQDALNIKCSFSEDCLR--KSRVEFCHEEMRTEMEVLKQQVQIYEE 209
+ +R + LQ + +++E+ +R +E H+E T + + +
Sbjct: 741 ----QASFEREREGLQSS-----AWTEEKVRGLTQELEQFHQEQLTSL--------VEKH 783
Query: 210 DFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKA-----CQMEKEKLEKQLKQM 263
+KE +E L + + ELQ+ E +++ NR SQI+A CQ E+ E L+ +
Sbjct: 784 TLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSL 842
Score = 45.4 bits (106), Expect = 7e-05
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 20/178 (11%)
Query: 96 RQRKDDRQREDDRQRDLT--------RDRLQREEKEKERLNEELHELKEENKLLKGKNTL 147
R +D+ R ++Q D T + QR E E L +++ +LK E L+G+ +
Sbjct: 632 RLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAV 691
Query: 148 ANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIY 207
+ C + K LQ L + + ++ LR ++ EME LK ++
Sbjct: 692 LKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLR----------LQHEME-LKARLTQA 740
Query: 208 EEDFKKERSDRERLNQEKEELQQIN-ETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
+ F++ER + +E+++ + E Q +L S ++ +EKE+L K+L + +
Sbjct: 741 QASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKH 798
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/272 (20%), Positives = 114/272 (41%), Gaps = 53/272 (19%)
Query: 30 KNLMNSLEQKIRCLEKQRKEL------------------LEVNQQWDQQFRSMKELYERK 71
++L+ ++Q +R EK R +L + ++ + R + E Y+ +
Sbjct: 376 RHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKER 435
Query: 72 VAELKTKL-DAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
+A LK +L E+ L K + +++ ++ + ++ + RDRL KE RL
Sbjct: 436 IAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE---NYIRDRLALSLKENSRL--- 489
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDAL-----NIKCSFSEDCLRKSR 185
EN+LL+ LA YE +L + L++ L ++ S +E L++ R
Sbjct: 490 ------ENELLENAEKLAE-----YENLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEER 538
Query: 186 VEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERL-----NQEKEE-------LQQINE 233
+ E + VL+ QV + + ++ R+ L N EE ++ +
Sbjct: 539 LTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHG 598
Query: 234 TSQSQLNRLNSQIKACQMEKEKLEKQLKQMYC 265
+ N LN I+A + ++ E+ + + C
Sbjct: 599 LGSEECNPLNMSIEAELVIEQMKEQHHRDICC 630
Score = 40.4 bits (93), Expect = 0.002
Identities = 63/292 (21%), Positives = 122/292 (41%), Gaps = 59/292 (20%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAE 74
E+S ++K E +R+N + L++++R +E + E LE N++ + +++ E
Sbjct: 1249 EASPKYKLLYEDVSREN--DCLQEELRMMETRYDEALENNKELTAEVFRLQD-------E 1299
Query: 75 LKTKLDAAERFLSTREKDPHQR-------------QRKDDRQREDDRQRD---LTRDRLQ 118
LK + E FLS + + Q K ++ +E QR L L+
Sbjct: 1300 LKKMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLE 1359
Query: 119 REEKEKE----RLNEELHEL--------------KEENKLLKGKNTLANKEKEHYECEIK 160
E E + +LN+ L E K+EN+ L+G L K K H EI
Sbjct: 1360 NLEIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAH---EIA 1416
Query: 161 RLNKALQDALNIKCSFSEDCLRKSRV-------EFCHEEMRTEMEVLKQQVQIYEEDFKK 213
L+ +Q ++ L ++ F H+ E+E+ K ++Q K+
Sbjct: 1417 WLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKE 1476
Query: 214 ------ERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQ 259
++ D +++EEL+ + Q + + +++ + E EKL+++
Sbjct: 1477 RVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQE 1528
Score = 35.4 bits (80), Expect = 0.070
Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 17/141 (12%)
Query: 137 ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC--------LRKSRVEF 188
EN+LL KN++ ++ EI+ L + + + K D L S V+
Sbjct: 353 ENELLVTKNSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDD 412
Query: 189 CHE--EMRTEM------EVLKQQVQIYEEDFKKERSD-RERLNQEKEELQQINETSQSQL 239
H E R E E K+++ + + +KER ++ +++ EL+Q E ++++
Sbjct: 413 HHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE 472
Query: 240 NRLNSQIKACQMEKEKLEKQL 260
N + ++ E +LE +L
Sbjct: 473 NYIRDRLALSLKENSRLENEL 493
Score = 33.9 bits (76), Expect = 0.20
Identities = 45/183 (24%), Positives = 72/183 (39%), Gaps = 37/183 (20%)
Query: 7 GTSRMIAAESSTEHKECAE------PSTRK-NLMNSLEQKIRCLEKQRKELLEVNQQWDQ 59
GT E + +EC + P+ RK + MNSLEQ++ + + + L + + D+
Sbjct: 1902 GTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKLDE 1961
Query: 60 QFRSMKELYERKVAELKTKLDAAERFLSTREKDPH-------QRQRKDDRQREDDRQRDL 112
Q M+ L R +T PH Q+Q RE Q L
Sbjct: 1962 QLMEMQHL----------------RSTATPSPSPHAWDLQLLQQQACPMVPREQFLQ--L 2003
Query: 113 TRDRLQREEKEKERLNEELHELKEENKLLKGKN----TLANKEKEHYECEIKRLNKALQD 168
R LQ E+ + L EEL E +G T+ + E ++K + + LQ+
Sbjct: 2004 QRQLLQ-AERINQHLQEELENRTSETNTPQGNQEQLVTVMEERMIEVEQKLKLVKRLLQE 2062
Query: 169 ALN 171
+N
Sbjct: 2063 KVN 2065
Score = 32.0 bits (71), Expect = 0.77
Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 34/261 (13%)
Query: 7 GTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKE 66
GTS + E E E A L NS E + E + ++ ++ +Q
Sbjct: 1165 GTSSVQRQEVKIEESE-ASVEGFSELENSEETRTESWEL-KNQISQLQEQLMMLCADCDR 1222
Query: 67 LYERK------VAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
E+K V+ LK KL ER E P + +D RE+D
Sbjct: 1223 ASEKKQDLLFDVSVLKKKLKMLERI---PEASPKYKLLYEDVSRENDC------------ 1267
Query: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC 180
L EEL ++ N E + E+K++ + + L+++ S+ E
Sbjct: 1268 ------LQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVK 1321
Query: 181 LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKE-ELQQINETSQSQL 239
+ + ++ ++E L++ V + D + E L E + + Q+N+T + +
Sbjct: 1322 IENEELNVLVLRLQGKIEKLQESV-VQRCDCCLWEASLENLEIEPDGNILQLNQTLEECV 1380
Query: 240 NRLNS---QIKACQMEKEKLE 257
R+ S I+ C+ E + LE
Sbjct: 1381 PRVRSVHHVIEECKQENQYLE 1401
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 62.4 bits (150), Expect = 5e-10
Identities = 64/298 (21%), Positives = 137/298 (45%), Gaps = 36/298 (12%)
Query: 35 SLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPH 94
++++ + L+KQ EL NQQ D + + + + +L+ L +EK+P
Sbjct: 1567 AVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1626
Query: 95 QRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEH 154
++ Q + + + +L R ++Q L EL E+K + +++ +N L E E
Sbjct: 1627 NSALEEREQEKFNLKEELERCKVQSSTLVSS-LEAELSEVKIQTHIVQQENHLLKDELE- 1684
Query: 155 YECEIKRLNKA-----LQDALNIKCSFSEDCLRKSRVEFCHEEMRT------EMEVLKQQ 203
++K+L++ Q ++ S++E L++ E EE+ + + +L+ +
Sbjct: 1685 ---KMKQLHRCPDLSDFQQKISSVLSYNEKLLKEK--EALSEELNSCVDKLAKSSLLEHR 1739
Query: 204 VQIYEEDFK----KERSDRERLNQEKEELQQINETSQS---QLNRLNSQIKACQMEKEKL 256
+ +++ K + S + +L +E++Q + +T Q+ Q++R+ S ++ Q EKE L
Sbjct: 1740 IATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEAL 1799
Query: 257 EKQLKQMYCPPCNCGLVFHLQDPWVP---TGPGAVQKQREHPPDYQWYALDQLPPDVQ 311
++++ ++ N G W P T P + Q++ W LD L + Q
Sbjct: 1800 KQEVMSLHKQLQNAG-----GKSWAPEIATHPSGLHNQQKR---LSWDKLDHLMNEEQ 1849
Score = 51.6 bits (122), Expect = 9e-07
Identities = 53/206 (25%), Positives = 89/206 (43%), Gaps = 37/206 (17%)
Query: 66 ELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKE 125
EL + K+ EL KL L ++KD K++ + +T +Q++ E
Sbjct: 1455 ELEKTKLQELTRKLKERVTIL-VKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKV---E 1510
Query: 126 RLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSR 185
L E +L++EN +L+ + T N+E ++ LN +
Sbjct: 1511 LLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGS-------------------- 1550
Query: 186 VEFCHEEMRTEMEVLKQQ---VQIYEEDFKKERSD----RERLNQEKEELQQINETSQSQ 238
EEM + E +KQ+ VQ E+ KK+ S+ ++L+ E EL Q N +Q +
Sbjct: 1551 ----QEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEK 1606
Query: 239 LNRLNSQI--KACQMEKEKLEKQLKQ 262
L LN ++ CQ EKE L++
Sbjct: 1607 LQELNQRLTEMLCQKEKEPGNSALEE 1632
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/271 (23%), Positives = 128/271 (47%), Gaps = 52/271 (19%)
Query: 1 MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSL--EQKIRCLEKQRKELLEVNQQWD 58
+ H ++ +R+ A++S E + R+ L +S E+K+R L + E+ Q
Sbjct: 721 LQHEMELKARLTQAQASFERE-------REGLQSSAWTEEKVRGLTQ------ELEQFHQ 767
Query: 59 QQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQR---EDDRQRDLTRD 115
+Q S+ E + + EL+ +L + HQR+ ++ R++ E +R+
Sbjct: 768 EQLTSLVEKHTLEKEELRKEL-----------LEKHQRELQEGREKMETECNRRTSQIEA 816
Query: 116 RLQRE-EKEKERLNEELHELKEENKL-LKGKNTLANKEKEHYECEIKRLNKALQDALNIK 173
+ Q + +K ER L L+ + LK +EK +E E +D L +
Sbjct: 817 QFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFE--------KDELTQE 868
Query: 174 CSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERS----DRERLNQEKEELQ 229
C+ +++ L+++ + +T VL Q+ ++ E+ +K+ + +R++L Q+ E+L+
Sbjct: 869 CAEAQELLKETL-----KREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLR 923
Query: 230 QINETSQS----QLNRLNSQIKACQMEKEKL 256
++ET QS Q+ L S K E+E++
Sbjct: 924 NVSETQQSLLSDQILELKSSHKRELREREEV 954
Score = 49.7 bits (117), Expect = 4e-06
Identities = 53/239 (22%), Positives = 105/239 (43%), Gaps = 42/239 (17%)
Query: 36 LEQKIRCLEKQRKELL----EVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREK 91
LE K+R EKQ E + + + Q+ + E+++++LK ++ + + ++
Sbjct: 629 LEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKE 688
Query: 92 DPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKE 151
H+ R E+ +Q + + + +EK RL E+ LK + T A
Sbjct: 689 AHHEATC---RHEEEKKQLQVKLEEEKTHLQEKLRLQHEME--------LKARLTQA--- 734
Query: 152 KEHYECEIKRLNKALQDALNIKCSFSEDCLR--KSRVEFCHEEMRTEMEVLKQQVQIYEE 209
+ +R + LQ + +++E+ +R +E H+E T + + +
Sbjct: 735 ----QASFEREREGLQSS-----AWTEEKVRGLTQELEQFHQEQLTSL--------VEKH 777
Query: 210 DFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKA-----CQMEKEKLEKQLKQM 263
+KE +E L + + ELQ+ E +++ NR SQI+A CQ E+ E L+ +
Sbjct: 778 TLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSL 836
Score = 45.4 bits (106), Expect = 7e-05
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 20/178 (11%)
Query: 96 RQRKDDRQREDDRQRDLT--------RDRLQREEKEKERLNEELHELKEENKLLKGKNTL 147
R +D+ R ++Q D T + QR E E L +++ +LK E L+G+ +
Sbjct: 626 RLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAV 685
Query: 148 ANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIY 207
+ C + K LQ L + + ++ LR ++ EME LK ++
Sbjct: 686 LKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLR----------LQHEME-LKARLTQA 734
Query: 208 EEDFKKERSDRERLNQEKEELQQIN-ETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
+ F++ER + +E+++ + E Q +L S ++ +EKE+L K+L + +
Sbjct: 735 QASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKH 792
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/272 (20%), Positives = 114/272 (41%), Gaps = 53/272 (19%)
Query: 30 KNLMNSLEQKIRCLEKQRKEL------------------LEVNQQWDQQFRSMKELYERK 71
++L+ ++Q +R EK R +L + ++ + R + E Y+ +
Sbjct: 370 RHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKER 429
Query: 72 VAELKTKL-DAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
+A LK +L E+ L K + +++ ++ + ++ + RDRL KE RL
Sbjct: 430 IAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE---NYIRDRLALSLKENSRL--- 483
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDAL-----NIKCSFSEDCLRKSR 185
EN+LL+ LA YE +L + L++ L ++ S +E L++ R
Sbjct: 484 ------ENELLENAEKLAE-----YENLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEER 532
Query: 186 VEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERL-----NQEKEE-------LQQINE 233
+ E + VL+ QV + + ++ R+ L N EE ++ +
Sbjct: 533 LTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHG 592
Query: 234 TSQSQLNRLNSQIKACQMEKEKLEKQLKQMYC 265
+ N LN I+A + ++ E+ + + C
Sbjct: 593 LGSEECNPLNMSIEAELVIEQMKEQHHRDICC 624
Score = 40.4 bits (93), Expect = 0.002
Identities = 63/292 (21%), Positives = 122/292 (41%), Gaps = 59/292 (20%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAE 74
E+S ++K E +R+N + L++++R +E + E LE N++ + +++ E
Sbjct: 1243 EASPKYKLLYEDVSREN--DCLQEELRMMETRYDEALENNKELTAEVFRLQD-------E 1293
Query: 75 LKTKLDAAERFLSTREKDPHQR-------------QRKDDRQREDDRQRD---LTRDRLQ 118
LK + E FLS + + Q K ++ +E QR L L+
Sbjct: 1294 LKKMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLE 1353
Query: 119 REEKEKE----RLNEELHEL--------------KEENKLLKGKNTLANKEKEHYECEIK 160
E E + +LN+ L E K+EN+ L+G L K K H EI
Sbjct: 1354 NLEIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAH---EIA 1410
Query: 161 RLNKALQDALNIKCSFSEDCLRKSRV-------EFCHEEMRTEMEVLKQQVQIYEEDFKK 213
L+ +Q ++ L ++ F H+ E+E+ K ++Q K+
Sbjct: 1411 WLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKE 1470
Query: 214 ------ERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQ 259
++ D +++EEL+ + Q + + +++ + E EKL+++
Sbjct: 1471 RVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQE 1522
Score = 35.4 bits (80), Expect = 0.070
Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 17/141 (12%)
Query: 137 ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC--------LRKSRVEF 188
EN+LL KN++ ++ EI+ L + + + K D L S V+
Sbjct: 347 ENELLVTKNSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDD 406
Query: 189 CHE--EMRTEM------EVLKQQVQIYEEDFKKERSD-RERLNQEKEELQQINETSQSQL 239
H E R E E K+++ + + +KER ++ +++ EL+Q E ++++
Sbjct: 407 HHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE 466
Query: 240 NRLNSQIKACQMEKEKLEKQL 260
N + ++ E +LE +L
Sbjct: 467 NYIRDRLALSLKENSRLENEL 487
Score = 33.9 bits (76), Expect = 0.20
Identities = 45/183 (24%), Positives = 72/183 (39%), Gaps = 37/183 (20%)
Query: 7 GTSRMIAAESSTEHKECAE------PSTRK-NLMNSLEQKIRCLEKQRKELLEVNQQWDQ 59
GT E + +EC + P+ RK + MNSLEQ++ + + + L + + D+
Sbjct: 1896 GTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKLDE 1955
Query: 60 QFRSMKELYERKVAELKTKLDAAERFLSTREKDPH-------QRQRKDDRQREDDRQRDL 112
Q M+ L R +T PH Q+Q RE Q L
Sbjct: 1956 QLMEMQHL----------------RSTATPSPSPHAWDLQLLQQQACPMVPREQFLQ--L 1997
Query: 113 TRDRLQREEKEKERLNEELHELKEENKLLKGKN----TLANKEKEHYECEIKRLNKALQD 168
R LQ E+ + L EEL E +G T+ + E ++K + + LQ+
Sbjct: 1998 QRQLLQ-AERINQHLQEELENRTSETNTPQGNQEQLVTVMEERMIEVEQKLKLVKRLLQE 2056
Query: 169 ALN 171
+N
Sbjct: 2057 KVN 2059
Score = 32.0 bits (71), Expect = 0.77
Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 34/261 (13%)
Query: 7 GTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKE 66
GTS + E E E A L NS E + E + ++ ++ +Q
Sbjct: 1159 GTSSVQRQEVKIEESE-ASVEGFSELENSEETRTESWEL-KNQISQLQEQLMMLCADCDR 1216
Query: 67 LYERK------VAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
E+K V+ LK KL ER E P + +D RE+D
Sbjct: 1217 ASEKKQDLLFDVSVLKKKLKMLERI---PEASPKYKLLYEDVSRENDC------------ 1261
Query: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC 180
L EEL ++ N E + E+K++ + + L+++ S+ E
Sbjct: 1262 ------LQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVK 1315
Query: 181 LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKE-ELQQINETSQSQL 239
+ + ++ ++E L++ V + D + E L E + + Q+N+T + +
Sbjct: 1316 IENEELNVLVLRLQGKIEKLQESV-VQRCDCCLWEASLENLEIEPDGNILQLNQTLEECV 1374
Query: 240 NRLNS---QIKACQMEKEKLE 257
R+ S I+ C+ E + LE
Sbjct: 1375 PRVRSVHHVIEECKQENQYLE 1395
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 62.4 bits (150), Expect = 5e-10
Identities = 64/298 (21%), Positives = 137/298 (45%), Gaps = 36/298 (12%)
Query: 35 SLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPH 94
++++ + L+KQ EL NQQ D + + + + +L+ L +EK+P
Sbjct: 1567 AVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1626
Query: 95 QRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEH 154
++ Q + + + +L R ++Q L EL E+K + +++ +N L E E
Sbjct: 1627 NSALEEREQEKFNLKEELERCKVQSSTLVSS-LEAELSEVKIQTHIVQQENHLLKDELE- 1684
Query: 155 YECEIKRLNKA-----LQDALNIKCSFSEDCLRKSRVEFCHEEMRT------EMEVLKQQ 203
++K+L++ Q ++ S++E L++ E EE+ + + +L+ +
Sbjct: 1685 ---KMKQLHRCPDLSDFQQKISSVLSYNEKLLKEK--EALSEELNSCVDKLAKSSLLEHR 1739
Query: 204 VQIYEEDFK----KERSDRERLNQEKEELQQINETSQS---QLNRLNSQIKACQMEKEKL 256
+ +++ K + S + +L +E++Q + +T Q+ Q++R+ S ++ Q EKE L
Sbjct: 1740 IATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEAL 1799
Query: 257 EKQLKQMYCPPCNCGLVFHLQDPWVP---TGPGAVQKQREHPPDYQWYALDQLPPDVQ 311
++++ ++ N G W P T P + Q++ W LD L + Q
Sbjct: 1800 KQEVMSLHKQLQNAG-----GKSWAPEIATHPSGLHNQQKR---LSWDKLDHLMNEEQ 1849
Score = 51.6 bits (122), Expect = 9e-07
Identities = 53/206 (25%), Positives = 89/206 (43%), Gaps = 37/206 (17%)
Query: 66 ELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKE 125
EL + K+ EL KL L ++KD K++ + +T +Q++ E
Sbjct: 1455 ELEKTKLQELTRKLKERVTIL-VKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKV---E 1510
Query: 126 RLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSR 185
L E +L++EN +L+ + T N+E ++ LN +
Sbjct: 1511 LLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGS-------------------- 1550
Query: 186 VEFCHEEMRTEMEVLKQQ---VQIYEEDFKKERSD----RERLNQEKEELQQINETSQSQ 238
EEM + E +KQ+ VQ E+ KK+ S+ ++L+ E EL Q N +Q +
Sbjct: 1551 ----QEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEK 1606
Query: 239 LNRLNSQI--KACQMEKEKLEKQLKQ 262
L LN ++ CQ EKE L++
Sbjct: 1607 LQELNQRLTEMLCQKEKEPGNSALEE 1632
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/271 (23%), Positives = 128/271 (47%), Gaps = 52/271 (19%)
Query: 1 MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSL--EQKIRCLEKQRKELLEVNQQWD 58
+ H ++ +R+ A++S E + R+ L +S E+K+R L + E+ Q
Sbjct: 721 LQHEMELKARLTQAQASFERE-------REGLQSSAWTEEKVRGLTQ------ELEQFHQ 767
Query: 59 QQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQR---EDDRQRDLTRD 115
+Q S+ E + + EL+ +L + HQR+ ++ R++ E +R+
Sbjct: 768 EQLTSLVEKHTLEKEELRKEL-----------LEKHQRELQEGREKMETECNRRTSQIEA 816
Query: 116 RLQRE-EKEKERLNEELHELKEENKL-LKGKNTLANKEKEHYECEIKRLNKALQDALNIK 173
+ Q + +K ER L L+ + LK +EK +E E +D L +
Sbjct: 817 QFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFE--------KDELTQE 868
Query: 174 CSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERS----DRERLNQEKEELQ 229
C+ +++ L+++ + +T VL Q+ ++ E+ +K+ + +R++L Q+ E+L+
Sbjct: 869 CAEAQELLKETL-----KREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLR 923
Query: 230 QINETSQS----QLNRLNSQIKACQMEKEKL 256
++ET QS Q+ L S K E+E++
Sbjct: 924 NVSETQQSLLSDQILELKSSHKRELREREEV 954
Score = 49.7 bits (117), Expect = 4e-06
Identities = 53/239 (22%), Positives = 105/239 (43%), Gaps = 42/239 (17%)
Query: 36 LEQKIRCLEKQRKELL----EVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREK 91
LE K+R EKQ E + + + Q+ + E+++++LK ++ + + ++
Sbjct: 629 LEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKE 688
Query: 92 DPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKE 151
H+ R E+ +Q + + + +EK RL E+ LK + T A
Sbjct: 689 AHHEATC---RHEEEKKQLQVKLEEEKTHLQEKLRLQHEME--------LKARLTQA--- 734
Query: 152 KEHYECEIKRLNKALQDALNIKCSFSEDCLR--KSRVEFCHEEMRTEMEVLKQQVQIYEE 209
+ +R + LQ + +++E+ +R +E H+E T + + +
Sbjct: 735 ----QASFEREREGLQSS-----AWTEEKVRGLTQELEQFHQEQLTSL--------VEKH 777
Query: 210 DFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKA-----CQMEKEKLEKQLKQM 263
+KE +E L + + ELQ+ E +++ NR SQI+A CQ E+ E L+ +
Sbjct: 778 TLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSL 836
Score = 45.4 bits (106), Expect = 7e-05
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 20/178 (11%)
Query: 96 RQRKDDRQREDDRQRDLT--------RDRLQREEKEKERLNEELHELKEENKLLKGKNTL 147
R +D+ R ++Q D T + QR E E L +++ +LK E L+G+ +
Sbjct: 626 RLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAV 685
Query: 148 ANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIY 207
+ C + K LQ L + + ++ LR ++ EME LK ++
Sbjct: 686 LKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLR----------LQHEME-LKARLTQA 734
Query: 208 EEDFKKERSDRERLNQEKEELQQIN-ETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
+ F++ER + +E+++ + E Q +L S ++ +EKE+L K+L + +
Sbjct: 735 QASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKH 792
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/272 (20%), Positives = 114/272 (41%), Gaps = 53/272 (19%)
Query: 30 KNLMNSLEQKIRCLEKQRKEL------------------LEVNQQWDQQFRSMKELYERK 71
++L+ ++Q +R EK R +L + ++ + R + E Y+ +
Sbjct: 370 RHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKER 429
Query: 72 VAELKTKL-DAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
+A LK +L E+ L K + +++ ++ + ++ + RDRL KE RL
Sbjct: 430 IAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE---NYIRDRLALSLKENSRL--- 483
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDAL-----NIKCSFSEDCLRKSR 185
EN+LL+ LA YE +L + L++ L ++ S +E L++ R
Sbjct: 484 ------ENELLENAEKLAE-----YENLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEER 532
Query: 186 VEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERL-----NQEKEE-------LQQINE 233
+ E + VL+ QV + + ++ R+ L N EE ++ +
Sbjct: 533 LTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHG 592
Query: 234 TSQSQLNRLNSQIKACQMEKEKLEKQLKQMYC 265
+ N LN I+A + ++ E+ + + C
Sbjct: 593 LGSEECNPLNMSIEAELVIEQMKEQHHRDICC 624
Score = 40.4 bits (93), Expect = 0.002
Identities = 63/292 (21%), Positives = 122/292 (41%), Gaps = 59/292 (20%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAE 74
E+S ++K E +R+N + L++++R +E + E LE N++ + +++ E
Sbjct: 1243 EASPKYKLLYEDVSREN--DCLQEELRMMETRYDEALENNKELTAEVFRLQD-------E 1293
Query: 75 LKTKLDAAERFLSTREKDPHQR-------------QRKDDRQREDDRQRD---LTRDRLQ 118
LK + E FLS + + Q K ++ +E QR L L+
Sbjct: 1294 LKKMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLE 1353
Query: 119 REEKEKE----RLNEELHEL--------------KEENKLLKGKNTLANKEKEHYECEIK 160
E E + +LN+ L E K+EN+ L+G L K K H EI
Sbjct: 1354 NLEIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAH---EIA 1410
Query: 161 RLNKALQDALNIKCSFSEDCLRKSRV-------EFCHEEMRTEMEVLKQQVQIYEEDFKK 213
L+ +Q ++ L ++ F H+ E+E+ K ++Q K+
Sbjct: 1411 WLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKE 1470
Query: 214 ------ERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQ 259
++ D +++EEL+ + Q + + +++ + E EKL+++
Sbjct: 1471 RVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQE 1522
Score = 35.4 bits (80), Expect = 0.070
Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 17/141 (12%)
Query: 137 ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC--------LRKSRVEF 188
EN+LL KN++ ++ EI+ L + + + K D L S V+
Sbjct: 347 ENELLVTKNSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDD 406
Query: 189 CHE--EMRTEM------EVLKQQVQIYEEDFKKERSD-RERLNQEKEELQQINETSQSQL 239
H E R E E K+++ + + +KER ++ +++ EL+Q E ++++
Sbjct: 407 HHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE 466
Query: 240 NRLNSQIKACQMEKEKLEKQL 260
N + ++ E +LE +L
Sbjct: 467 NYIRDRLALSLKENSRLENEL 487
Score = 32.0 bits (71), Expect = 0.77
Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 34/261 (13%)
Query: 7 GTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKE 66
GTS + E E E A L NS E + E + ++ ++ +Q
Sbjct: 1159 GTSSVQRQEVKIEESE-ASVEGFSELENSEETRTESWEL-KNQISQLQEQLMMLCADCDR 1216
Query: 67 LYERK------VAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
E+K V+ LK KL ER E P + +D RE+D
Sbjct: 1217 ASEKKQDLLFDVSVLKKKLKMLERI---PEASPKYKLLYEDVSRENDC------------ 1261
Query: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC 180
L EEL ++ N E + E+K++ + + L+++ S+ E
Sbjct: 1262 ------LQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVK 1315
Query: 181 LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKE-ELQQINETSQSQL 239
+ + ++ ++E L++ V + D + E L E + + Q+N+T + +
Sbjct: 1316 IENEELNVLVLRLQGKIEKLQESV-VQRCDCCLWEASLENLEIEPDGNILQLNQTLEECV 1374
Query: 240 NRLNS---QIKACQMEKEKLE 257
R+ S I+ C+ E + LE
Sbjct: 1375 PRVRSVHHVIEECKQENQYLE 1395
Score = 30.8 bits (68), Expect = 1.7
Identities = 36/141 (25%), Positives = 56/141 (39%), Gaps = 37/141 (26%)
Query: 7 GTSRMIAAESSTEHKECAE------PSTRK-NLMNSLEQKIRCLEKQRKELLEVNQQWDQ 59
GT E + +EC + P+ RK + MNSLEQ++ + + + L + + D+
Sbjct: 1896 GTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKLDE 1955
Query: 60 QFRSMKELYERKVAELKTKLDAAERFLSTREKDPH-------QRQRKDDRQREDDRQRDL 112
Q M+ L R +T PH Q+Q RE Q
Sbjct: 1956 QLMEMQHL----------------RSTATPSPSPHAWDLQLLQQQACPMVPREQFLQ--- 1996
Query: 113 TRDRLQREEKEKERLNEELHE 133
LQR+ + ER+N+ L E
Sbjct: 1997 ----LQRQLLQAERINQHLQE 2013
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 62.4 bits (150), Expect = 5e-10
Identities = 64/298 (21%), Positives = 137/298 (45%), Gaps = 36/298 (12%)
Query: 35 SLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPH 94
++++ + L+KQ EL NQQ D + + + + +L+ L +EK+P
Sbjct: 1567 AVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1626
Query: 95 QRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEH 154
++ Q + + + +L R ++Q L EL E+K + +++ +N L E E
Sbjct: 1627 NSALEEREQEKFNLKEELERCKVQSSTLVSS-LEAELSEVKIQTHIVQQENHLLKDELE- 1684
Query: 155 YECEIKRLNKA-----LQDALNIKCSFSEDCLRKSRVEFCHEEMRT------EMEVLKQQ 203
++K+L++ Q ++ S++E L++ E EE+ + + +L+ +
Sbjct: 1685 ---KMKQLHRCPDLSDFQQKISSVLSYNEKLLKEK--EALSEELNSCVDKLAKSSLLEHR 1739
Query: 204 VQIYEEDFK----KERSDRERLNQEKEELQQINETSQS---QLNRLNSQIKACQMEKEKL 256
+ +++ K + S + +L +E++Q + +T Q+ Q++R+ S ++ Q EKE L
Sbjct: 1740 IATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEAL 1799
Query: 257 EKQLKQMYCPPCNCGLVFHLQDPWVP---TGPGAVQKQREHPPDYQWYALDQLPPDVQ 311
++++ ++ N G W P T P + Q++ W LD L + Q
Sbjct: 1800 KQEVMSLHKQLQNAG-----GKSWAPEIATHPSGLHNQQKR---LSWDKLDHLMNEEQ 1849
Score = 51.6 bits (122), Expect = 9e-07
Identities = 53/206 (25%), Positives = 89/206 (43%), Gaps = 37/206 (17%)
Query: 66 ELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKE 125
EL + K+ EL KL L ++KD K++ + +T +Q++ E
Sbjct: 1455 ELEKTKLQELTRKLKERVTIL-VKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKV---E 1510
Query: 126 RLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSR 185
L E +L++EN +L+ + T N+E ++ LN +
Sbjct: 1511 LLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGS-------------------- 1550
Query: 186 VEFCHEEMRTEMEVLKQQ---VQIYEEDFKKERSD----RERLNQEKEELQQINETSQSQ 238
EEM + E +KQ+ VQ E+ KK+ S+ ++L+ E EL Q N +Q +
Sbjct: 1551 ----QEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEK 1606
Query: 239 LNRLNSQI--KACQMEKEKLEKQLKQ 262
L LN ++ CQ EKE L++
Sbjct: 1607 LQELNQRLTEMLCQKEKEPGNSALEE 1632
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/271 (23%), Positives = 128/271 (47%), Gaps = 52/271 (19%)
Query: 1 MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSL--EQKIRCLEKQRKELLEVNQQWD 58
+ H ++ +R+ A++S E + R+ L +S E+K+R L + E+ Q
Sbjct: 721 LQHEMELKARLTQAQASFERE-------REGLQSSAWTEEKVRGLTQ------ELEQFHQ 767
Query: 59 QQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQR---EDDRQRDLTRD 115
+Q S+ E + + EL+ +L + HQR+ ++ R++ E +R+
Sbjct: 768 EQLTSLVEKHTLEKEELRKEL-----------LEKHQRELQEGREKMETECNRRTSQIEA 816
Query: 116 RLQRE-EKEKERLNEELHELKEENKL-LKGKNTLANKEKEHYECEIKRLNKALQDALNIK 173
+ Q + +K ER L L+ + LK +EK +E E +D L +
Sbjct: 817 QFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFE--------KDELTQE 868
Query: 174 CSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERS----DRERLNQEKEELQ 229
C+ +++ L+++ + +T VL Q+ ++ E+ +K+ + +R++L Q+ E+L+
Sbjct: 869 CAEAQELLKETL-----KREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLR 923
Query: 230 QINETSQS----QLNRLNSQIKACQMEKEKL 256
++ET QS Q+ L S K E+E++
Sbjct: 924 NVSETQQSLLSDQILELKSSHKRELREREEV 954
Score = 49.7 bits (117), Expect = 4e-06
Identities = 53/239 (22%), Positives = 105/239 (43%), Gaps = 42/239 (17%)
Query: 36 LEQKIRCLEKQRKELL----EVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREK 91
LE K+R EKQ E + + + Q+ + E+++++LK ++ + + ++
Sbjct: 629 LEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKE 688
Query: 92 DPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKE 151
H+ R E+ +Q + + + +EK RL E+ LK + T A
Sbjct: 689 AHHEATC---RHEEEKKQLQVKLEEEKTHLQEKLRLQHEME--------LKARLTQA--- 734
Query: 152 KEHYECEIKRLNKALQDALNIKCSFSEDCLR--KSRVEFCHEEMRTEMEVLKQQVQIYEE 209
+ +R + LQ + +++E+ +R +E H+E T + + +
Sbjct: 735 ----QASFEREREGLQSS-----AWTEEKVRGLTQELEQFHQEQLTSL--------VEKH 777
Query: 210 DFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKA-----CQMEKEKLEKQLKQM 263
+KE +E L + + ELQ+ E +++ NR SQI+A CQ E+ E L+ +
Sbjct: 778 TLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSL 836
Score = 45.4 bits (106), Expect = 7e-05
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 20/178 (11%)
Query: 96 RQRKDDRQREDDRQRDLT--------RDRLQREEKEKERLNEELHELKEENKLLKGKNTL 147
R +D+ R ++Q D T + QR E E L +++ +LK E L+G+ +
Sbjct: 626 RLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAV 685
Query: 148 ANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIY 207
+ C + K LQ L + + ++ LR ++ EME LK ++
Sbjct: 686 LKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLR----------LQHEME-LKARLTQA 734
Query: 208 EEDFKKERSDRERLNQEKEELQQIN-ETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
+ F++ER + +E+++ + E Q +L S ++ +EKE+L K+L + +
Sbjct: 735 QASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKH 792
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/272 (20%), Positives = 114/272 (41%), Gaps = 53/272 (19%)
Query: 30 KNLMNSLEQKIRCLEKQRKEL------------------LEVNQQWDQQFRSMKELYERK 71
++L+ ++Q +R EK R +L + ++ + R + E Y+ +
Sbjct: 370 RHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKER 429
Query: 72 VAELKTKL-DAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
+A LK +L E+ L K + +++ ++ + ++ + RDRL KE RL
Sbjct: 430 IAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE---NYIRDRLALSLKENSRL--- 483
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDAL-----NIKCSFSEDCLRKSR 185
EN+LL+ LA YE +L + L++ L ++ S +E L++ R
Sbjct: 484 ------ENELLENAEKLAE-----YENLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEER 532
Query: 186 VEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERL-----NQEKEE-------LQQINE 233
+ E + VL+ QV + + ++ R+ L N EE ++ +
Sbjct: 533 LTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHG 592
Query: 234 TSQSQLNRLNSQIKACQMEKEKLEKQLKQMYC 265
+ N LN I+A + ++ E+ + + C
Sbjct: 593 LGSEECNPLNMSIEAELVIEQMKEQHHRDICC 624
Score = 40.4 bits (93), Expect = 0.002
Identities = 63/292 (21%), Positives = 122/292 (41%), Gaps = 59/292 (20%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAE 74
E+S ++K E +R+N + L++++R +E + E LE N++ + +++ E
Sbjct: 1243 EASPKYKLLYEDVSREN--DCLQEELRMMETRYDEALENNKELTAEVFRLQD-------E 1293
Query: 75 LKTKLDAAERFLSTREKDPHQR-------------QRKDDRQREDDRQRD---LTRDRLQ 118
LK + E FLS + + Q K ++ +E QR L L+
Sbjct: 1294 LKKMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLE 1353
Query: 119 REEKEKE----RLNEELHEL--------------KEENKLLKGKNTLANKEKEHYECEIK 160
E E + +LN+ L E K+EN+ L+G L K K H EI
Sbjct: 1354 NLEIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAH---EIA 1410
Query: 161 RLNKALQDALNIKCSFSEDCLRKSRV-------EFCHEEMRTEMEVLKQQVQIYEEDFKK 213
L+ +Q ++ L ++ F H+ E+E+ K ++Q K+
Sbjct: 1411 WLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKE 1470
Query: 214 ------ERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQ 259
++ D +++EEL+ + Q + + +++ + E EKL+++
Sbjct: 1471 RVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQE 1522
Score = 37.7 bits (86), Expect = 0.014
Identities = 53/243 (21%), Positives = 94/243 (38%), Gaps = 40/243 (16%)
Query: 7 GTSRMIAAESSTEHKECAE------PSTRK-NLMNSLEQKIRCLEKQRKELLEVNQQWDQ 59
GT E + +EC + P+ RK + MNSLEQ++ + + + L + + D+
Sbjct: 1896 GTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKLDE 1955
Query: 60 QFRSMKELYERKVAELKTKLDAAERFLSTREKDPH-------QRQRKDDRQREDDRQRDL 112
Q M+ L R +T PH Q+Q RE Q L
Sbjct: 1956 QLMEMQHL----------------RSTATPSPSPHAWDLQLLQQQACPMVPREQFLQ--L 1997
Query: 113 TRDRLQREEKEKERLNEELHELKEENKLLKGKN----TLANKEKEHYECEIKRLNKALQD 168
R LQ E+ + L EEL E +G T+ + E ++K + + LQ+
Sbjct: 1998 QRQLLQ-AERINQHLQEELENRTSETNTPQGNQEQLVTVMEERMIEVEQKLKLVKRLLQE 2056
Query: 169 ALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEEL 228
+N E + ++ + +++ E L + +++ E+ K L ++ L
Sbjct: 2057 KVN---QLKEQLCKNTKADAMVKDLYVENAQLLKALEVTEQRQKTAEKKNYLLEEKIASL 2113
Query: 229 QQI 231
I
Sbjct: 2114 SNI 2116
Score = 35.4 bits (80), Expect = 0.070
Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 17/141 (12%)
Query: 137 ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC--------LRKSRVEF 188
EN+LL KN++ ++ EI+ L + + + K D L S V+
Sbjct: 347 ENELLVTKNSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDD 406
Query: 189 CHE--EMRTEM------EVLKQQVQIYEEDFKKERSD-RERLNQEKEELQQINETSQSQL 239
H E R E E K+++ + + +KER ++ +++ EL+Q E ++++
Sbjct: 407 HHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEE 466
Query: 240 NRLNSQIKACQMEKEKLEKQL 260
N + ++ E +LE +L
Sbjct: 467 NYIRDRLALSLKENSRLENEL 487
Score = 32.0 bits (71), Expect = 0.77
Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 34/261 (13%)
Query: 7 GTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKE 66
GTS + E E E A L NS E + E + ++ ++ +Q
Sbjct: 1159 GTSSVQRQEVKIEESE-ASVEGFSELENSEETRTESWEL-KNQISQLQEQLMMLCADCDR 1216
Query: 67 LYERK------VAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQRE 120
E+K V+ LK KL ER E P + +D RE+D
Sbjct: 1217 ASEKKQDLLFDVSVLKKKLKMLERI---PEASPKYKLLYEDVSRENDC------------ 1261
Query: 121 EKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDC 180
L EEL ++ N E + E+K++ + + L+++ S+ E
Sbjct: 1262 ------LQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVK 1315
Query: 181 LRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKE-ELQQINETSQSQL 239
+ + ++ ++E L++ V + D + E L E + + Q+N+T + +
Sbjct: 1316 IENEELNVLVLRLQGKIEKLQESV-VQRCDCCLWEASLENLEIEPDGNILQLNQTLEECV 1374
Query: 240 NRLNS---QIKACQMEKEKLE 257
R+ S I+ C+ E + LE
Sbjct: 1375 PRVRSVHHVIEECKQENQYLE 1395
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 61.6 bits (148), Expect = 9e-10
Identities = 68/266 (25%), Positives = 132/266 (49%), Gaps = 38/266 (14%)
Query: 20 HKECAEPSTRKNLMNSLEQKIRC--------LEKQRKELLEVNQ-QWDQQFRSMKELYER 70
+++ E +K L + E K + LEK+R+ L+E Q + +++ + KE +ER
Sbjct: 347 YQKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWER 406
Query: 71 KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
K EL+ + + L R ++QR+ +RQRE++R++D+ R ++E E++R E
Sbjct: 407 KQRELQEQEWKKQLELEKRL----EKQRELERQREEERRKDIERREAAKQELERQRRLE- 461
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQ-DALNIKCSFSEDCLRKSRVEFC 189
E +LL KN +++E K+ N L+ +ALN K L+ R++
Sbjct: 462 -WERIRRQELLNQKN---REQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLK-- 515
Query: 190 HEEMRTEMEVLKQQVQIYEEDFKKERSD-------------RERLNQEKEELQQINETSQ 236
+ +TE+EVL +Q + + K+ + + ++L E+ + Q + T
Sbjct: 516 KQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPD 575
Query: 237 SQLNRLNSQIKACQMEKEKLEKQLKQ 262
S ++ L+ + +EKE+L ++LK+
Sbjct: 576 SGVSLLHKK----SLEKEELCQRLKE 597
Score = 47.0 bits (110), Expect = 2e-05
Identities = 38/149 (25%), Positives = 77/149 (51%), Gaps = 20/149 (13%)
Query: 20 HKECAEPSTRKNLMNSLEQKIRCLEKQ-----------RKELLEVNQQWDQQFRSMKELY 68
HK+ E ++ L L++++ LEK+ +L E+ + ++ Q ++++LY
Sbjct: 582 HKKSLE---KEELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRETYNTQQLALEQLY 638
Query: 69 ERKVAELK----TKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEK 124
+ K +LK +L+ ++ E +Q K++ +E+ R+ + + + +EEK +
Sbjct: 639 KIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQ 698
Query: 125 ERLNEELHELKEENKLLKGKNTLANKEKE 153
E++ EE E K E K K K+TL +EK+
Sbjct: 699 EKIQEE--ERKAEEKQRKDKDTLKAEEKK 725
Score = 39.7 bits (91), Expect = 0.004
Identities = 46/225 (20%), Positives = 103/225 (45%), Gaps = 12/225 (5%)
Query: 38 QKIRCLEKQRKELLEV-NQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
Q +R ++ +K LEV ++Q D + +K+L ++++ E + KL +L ++ ++R
Sbjct: 510 QDVRLKKQTQKTELEVLDKQCDLEIMEIKQL-QQELQEYQNKLI----YLVPEKQLLNER 564
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYE 156
+ D L + +E+ +RL E+L L++E + N + +
Sbjct: 565 IKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKELR 624
Query: 157 CEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQ----IYEEDFK 212
AL+ IK ++ RK R+E ++ + E E ++ Q +++E+ +
Sbjct: 625 ETYNTQQLALEQLYKIKRDKLKEIERK-RLELMQKK-KLEDEAARKAKQGKENLWKENLR 682
Query: 213 KERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLE 257
KE ++++ QE++ ++I E + + + E++K E
Sbjct: 683 KEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRE 727
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 61.6 bits (148), Expect = 9e-10
Identities = 68/266 (25%), Positives = 132/266 (49%), Gaps = 38/266 (14%)
Query: 20 HKECAEPSTRKNLMNSLEQKIRC--------LEKQRKELLEVNQ-QWDQQFRSMKELYER 70
+++ E +K L + E K + LEK+R+ L+E Q + +++ + KE +ER
Sbjct: 347 YQKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWER 406
Query: 71 KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
K EL+ + + L R ++QR+ +RQRE++R++D+ R ++E E++R E
Sbjct: 407 KQRELQEQEWKKQLELEKRL----EKQRELERQREEERRKDIERREAAKQELERQRRLE- 461
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQ-DALNIKCSFSEDCLRKSRVEFC 189
E +LL KN +++E K+ N L+ +ALN K L+ R++
Sbjct: 462 -WERIRRQELLNQKN---REQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLK-- 515
Query: 190 HEEMRTEMEVLKQQVQIYEEDFKKERSD-------------RERLNQEKEELQQINETSQ 236
+ +TE+EVL +Q + + K+ + + ++L E+ + Q + T
Sbjct: 516 KQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPD 575
Query: 237 SQLNRLNSQIKACQMEKEKLEKQLKQ 262
S ++ L+ + +EKE+L ++LK+
Sbjct: 576 SGVSLLHKK----SLEKEELCQRLKE 597
Score = 39.7 bits (91), Expect = 0.004
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 31 NLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY----------ERKVAEL--KTK 78
+++ L + CL L E+ + ++ Q ++++LY ERK EL K K
Sbjct: 628 SVLQCLLSLLSCLNNLFLLLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKK 687
Query: 79 LD--AAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREE-KEKERLNEELHELK 135
L+ AA + +E + RK++ +++ Q + T++++Q EE K +E+ ++ LK
Sbjct: 688 LEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLK 747
Query: 136 EENKLLKGKNTLAN 149
E K + + L N
Sbjct: 748 AEEKKRETASVLVN 761
Score = 31.6 bits (70), Expect = 1.0
Identities = 47/251 (18%), Positives = 112/251 (44%), Gaps = 37/251 (14%)
Query: 38 QKIRCLEKQRKELLEV-NQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
Q +R ++ +K LEV ++Q D + +K+L ++++ E + KL +L ++ ++R
Sbjct: 510 QDVRLKKQTQKTELEVLDKQCDLEIMEIKQL-QQELQEYQNKLI----YLVPEKQLLNER 564
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEE-----NKLLKGKNTL--AN 149
+ D L + +E+ +RL E+L L++E +++ N L N
Sbjct: 565 IKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKCGN 624
Query: 150 KEKEHYECEIKRLN---------KALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVL 200
+ +C + L+ K L++ N + + + L K + + E R +E++
Sbjct: 625 MDDSVLQCLLSLLSCLNNLFLLLKELRETYNTQ-QLALEQLYKIKRDKLKEIERKRLELM 683
Query: 201 KQQV--------------QIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQI 246
+++ +++E+ +KE ++++ QE++ ++I E + +
Sbjct: 684 QKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDK 743
Query: 247 KACQMEKEKLE 257
+ E++K E
Sbjct: 744 DTLKAEEKKRE 754
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 61.6 bits (148), Expect = 9e-10
Identities = 68/266 (25%), Positives = 132/266 (49%), Gaps = 38/266 (14%)
Query: 20 HKECAEPSTRKNLMNSLEQKIRC--------LEKQRKELLEVNQ-QWDQQFRSMKELYER 70
+++ E +K L + E K + LEK+R+ L+E Q + +++ + KE +ER
Sbjct: 347 YQKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWER 406
Query: 71 KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
K EL+ + + L R ++QR+ +RQRE++R++D+ R ++E E++R E
Sbjct: 407 KQRELQEQEWKKQLELEKRL----EKQRELERQREEERRKDIERREAAKQELERQRRLE- 461
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQ-DALNIKCSFSEDCLRKSRVEFC 189
E +LL KN +++E K+ N L+ +ALN K L+ R++
Sbjct: 462 -WERIRRQELLNQKN---REQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLK-- 515
Query: 190 HEEMRTEMEVLKQQVQIYEEDFKKERSD-------------RERLNQEKEELQQINETSQ 236
+ +TE+EVL +Q + + K+ + + ++L E+ + Q + T
Sbjct: 516 KQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPD 575
Query: 237 SQLNRLNSQIKACQMEKEKLEKQLKQ 262
S ++ L+ + +EKE+L ++LK+
Sbjct: 576 SGVSLLHKK----SLEKEELCQRLKE 597
Score = 39.7 bits (91), Expect = 0.004
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 31 NLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY----------ERKVAEL--KTK 78
+++ L + CL L E+ + ++ Q ++++LY ERK EL K K
Sbjct: 628 SVLQCLLSLLSCLNNLFLLLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKK 687
Query: 79 LD--AAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREE-KEKERLNEELHELK 135
L+ AA + +E + RK++ +++ Q + T++++Q EE K +E+ ++ LK
Sbjct: 688 LEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLK 747
Query: 136 EENKLLKGKNTLAN 149
E K + + L N
Sbjct: 748 AEEKKRETASVLVN 761
Score = 31.6 bits (70), Expect = 1.0
Identities = 47/251 (18%), Positives = 112/251 (44%), Gaps = 37/251 (14%)
Query: 38 QKIRCLEKQRKELLEV-NQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
Q +R ++ +K LEV ++Q D + +K+L ++++ E + KL +L ++ ++R
Sbjct: 510 QDVRLKKQTQKTELEVLDKQCDLEIMEIKQL-QQELQEYQNKLI----YLVPEKQLLNER 564
Query: 97 QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEE-----NKLLKGKNTL--AN 149
+ D L + +E+ +RL E+L L++E +++ N L N
Sbjct: 565 IKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKCGN 624
Query: 150 KEKEHYECEIKRLN---------KALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVL 200
+ +C + L+ K L++ N + + + L K + + E R +E++
Sbjct: 625 MDDSVLQCLLSLLSCLNNLFLLLKELRETYNTQ-QLALEQLYKIKRDKLKEIERKRLELM 683
Query: 201 KQQV--------------QIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQI 246
+++ +++E+ +KE ++++ QE++ ++I E + +
Sbjct: 684 QKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDK 743
Query: 247 KACQMEKEKLE 257
+ E++K E
Sbjct: 744 DTLKAEEKKRE 754
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 60.8 bits (146), Expect = 2e-09
Identities = 59/241 (24%), Positives = 109/241 (45%), Gaps = 39/241 (16%)
Query: 29 RKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDA---AERF 85
+ +L L+QK R +QR+ ++ + + ++E ERK+ EL+ +A AER
Sbjct: 318 KTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERL 377
Query: 86 LSTREKDPHQRQRK-----DDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKL 140
L E+ + R+ + + RE ++ R + ++ +E+E R + + EL+E
Sbjct: 378 LQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQ-- 435
Query: 141 LKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVL 200
+RL +ALQ L +K E+ +R ++ E E E L
Sbjct: 436 -------------------QRLQEALQ--LEVKARRDEESVRIAQTRLLEE----EEEKL 470
Query: 201 KQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQL 260
KQ +Q+ EE + ER QEKEELQQ L + Q++ + +++ ++ +
Sbjct: 471 KQLMQLKEE----QERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDV 526
Query: 261 K 261
+
Sbjct: 527 E 527
Score = 53.9 bits (128), Expect = 2e-07
Identities = 56/217 (25%), Positives = 102/217 (47%), Gaps = 30/217 (13%)
Query: 59 QQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQ-RDLTRDRL 117
Q++ + ++ R AE KT L KD Q++R+ QRE R ++ RL
Sbjct: 301 QEWTAAIQMAIRLQAEGKTSL----------HKDLKQKRREQREQRERRRAAKEEELLRL 350
Query: 118 QREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQ----DALNIK 173
Q+ ++EKER +EL L+E + + L +E+E + + L +AL+ +A +
Sbjct: 351 QQLQEEKERKLQELELLQEAQRQAE---RLLQEEEERRRSQHRELQQALEGQLREAEQAR 407
Query: 174 CSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRER--------LNQEK 225
S + K + E+E ++Q++Q + K R D E L +E+
Sbjct: 408 ASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEE 467
Query: 226 EELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
E+L+Q+ + + Q I+ Q EKE+L++++ Q
Sbjct: 468 EKLKQLMQLKEEQ----ERYIERAQQEKEELQQEMAQ 500
Score = 30.8 bits (68), Expect = 1.7
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 15/167 (8%)
Query: 13 AAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQ----RKELLEVNQQWDQQFRSMKELY 68
AA KE E R LE K R E+ + LLE ++ +Q +KE
Sbjct: 421 AARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQ 480
Query: 69 ERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKE--- 125
ER + + + + ++ ++ + + Q Q++ + R++ ++ D + QR+ ++
Sbjct: 481 ERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNV 540
Query: 126 -----RLNEELHELKEENKLLKGKNTLANKEK---EHYECEIKRLNK 164
++N +H ++ +K ++ + + H + +KRL +
Sbjct: 541 KHWNVQMNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRLTR 587
>gi|187608545 centrosomal protein 55kDa [Homo sapiens]
Length = 464
Score = 60.1 bits (144), Expect = 3e-09
Identities = 68/270 (25%), Positives = 121/270 (44%), Gaps = 42/270 (15%)
Query: 8 TSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQW---DQQFRSM 64
TSR+ ES T ++ + N NS I +E Q K+ LE NQQW DQQ
Sbjct: 136 TSRIAELESKTNTLRLSQ-TVAPNCFNSSINNIHEMEIQLKDALEKNQQWLVYDQQ---- 190
Query: 65 KELYER----KVAELKTKLDAAERFLSTREKDPHQR-----------------QRKD--- 100
+E+Y + K+ EL+ K + A L + K P +KD
Sbjct: 191 REVYVKGLLAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEV 250
Query: 101 DRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIK 160
+RQ +L+ R + EE +KE N L++L + ++ ++ K +++
Sbjct: 251 ERQTITQLSFELSEFRRKYEETQKEVHN--LNQLLYSQRRADVQHLEDDRHKTEKIQKLR 308
Query: 161 RLNKALQDALNIKCSFSEDCLRKSRVEFCH------EEMRTEMEVLKQQVQIYEEDFKKE 214
N + L + SE+ L S+V+F + +E +T + +L+QQ+Q DF+ E
Sbjct: 309 EENDIARGKLEEEKKRSEELL--SQVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENE 366
Query: 215 RSDRERLNQEKEELQQINETSQSQLNRLNS 244
+ DR+ + + + + +++Q+ +L S
Sbjct: 367 KLDRQHVQHQLHVILKELRKARNQITQLES 396
Score = 29.6 bits (65), Expect = 3.8
Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 10/140 (7%)
Query: 111 DLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLN---KALQ 167
++T + + +KE+ RL E++ L+ E K KN EK+ EI+RL KA
Sbjct: 43 EITSGKGKLTDKERHRLLEKIRVLEAE----KEKNAYQLTEKDK---EIQRLRDQLKARY 95
Query: 168 DALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEE 227
+ E R E + + E +VLKQQ+ + S L +
Sbjct: 96 STTALLEQLEETTREGERREQVLKALSEEKDVLKQQLSAATSRIAELESKTNTLRLSQTV 155
Query: 228 LQQINETSQSQLNRLNSQIK 247
+S + ++ + Q+K
Sbjct: 156 APNCFNSSINNIHEMEIQLK 175
>gi|187608537 centrosomal protein 55kDa [Homo sapiens]
Length = 464
Score = 60.1 bits (144), Expect = 3e-09
Identities = 68/270 (25%), Positives = 121/270 (44%), Gaps = 42/270 (15%)
Query: 8 TSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQW---DQQFRSM 64
TSR+ ES T ++ + N NS I +E Q K+ LE NQQW DQQ
Sbjct: 136 TSRIAELESKTNTLRLSQ-TVAPNCFNSSINNIHEMEIQLKDALEKNQQWLVYDQQ---- 190
Query: 65 KELYER----KVAELKTKLDAAERFLSTREKDPHQR-----------------QRKD--- 100
+E+Y + K+ EL+ K + A L + K P +KD
Sbjct: 191 REVYVKGLLAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEV 250
Query: 101 DRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIK 160
+RQ +L+ R + EE +KE N L++L + ++ ++ K +++
Sbjct: 251 ERQTITQLSFELSEFRRKYEETQKEVHN--LNQLLYSQRRADVQHLEDDRHKTEKIQKLR 308
Query: 161 RLNKALQDALNIKCSFSEDCLRKSRVEFCH------EEMRTEMEVLKQQVQIYEEDFKKE 214
N + L + SE+ L S+V+F + +E +T + +L+QQ+Q DF+ E
Sbjct: 309 EENDIARGKLEEEKKRSEELL--SQVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENE 366
Query: 215 RSDRERLNQEKEELQQINETSQSQLNRLNS 244
+ DR+ + + + + +++Q+ +L S
Sbjct: 367 KLDRQHVQHQLHVILKELRKARNQITQLES 396
Score = 29.6 bits (65), Expect = 3.8
Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 10/140 (7%)
Query: 111 DLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLN---KALQ 167
++T + + +KE+ RL E++ L+ E K KN EK+ EI+RL KA
Sbjct: 43 EITSGKGKLTDKERHRLLEKIRVLEAE----KEKNAYQLTEKDK---EIQRLRDQLKARY 95
Query: 168 DALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEE 227
+ E R E + + E +VLKQQ+ + S L +
Sbjct: 96 STTALLEQLEETTREGERREQVLKALSEEKDVLKQQLSAATSRIAELESKTNTLRLSQTV 155
Query: 228 LQQINETSQSQLNRLNSQIK 247
+S + ++ + Q+K
Sbjct: 156 APNCFNSSINNIHEMEIQLK 175
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 59.7 bits (143), Expect = 3e-09
Identities = 63/270 (23%), Positives = 132/270 (48%), Gaps = 21/270 (7%)
Query: 3 HFVQGTSRMIAAESSTEHKEC---AEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQ 59
HF R ++A S T HK+ E T++ SLE + + EL + N + +
Sbjct: 176 HFAGELQRALSAVS-TRHKKADRYIEELTKERDALSLELYRNTITNE--ELKKKNAELQE 232
Query: 60 QF---RSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQ--RKDDRQREDDRQRDLTR 114
+ S K + V ELK KL+ A+ L + + Q + R+++ RE +++
Sbjct: 233 KLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 292
Query: 115 DRLQREEKEKERLNEELHELKE-ENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIK 173
+++ R+E ERL E+ +++E E K+ + + L +EK E++ K L++ ++
Sbjct: 293 EKMWRQE---ERLREQEGKMREQEEKMWRQEKRLREQEK-----ELREQEKELREQKELR 344
Query: 174 CSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINE 233
+ ++ ++ E+MR + E + +Q + E K+ R +++ ++E + + +E
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404
Query: 234 TSQSQLNRLNSQIKAC-QMEKEKLEKQLKQ 262
+ + R+ Q K Q+EK + EK++++
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQE 434
Score = 58.9 bits (141), Expect = 6e-09
Identities = 52/233 (22%), Positives = 120/233 (51%), Gaps = 17/233 (7%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYER--KVAELKTKLDAAERFLSTREKDPH 94
E+++R EK+ +E E+ +Q +Q ++++E+ K+ E + K+ E L +EK
Sbjct: 327 EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386
Query: 95 QRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLL-KGKNTLANKEKE 153
++++K Q E ++D + +E+E++ E++ +++EE K+ + K T +EK
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
Query: 154 HYECEIKRLNKALQDALNIKCSFSEDCLR--KSRVEFCHEEMRTEMEVLKQQVQIYEEDF 211
E I+ K +++ E+ +R + +++ E M + E QQ ++ E+
Sbjct: 447 QEEERIREREKKMRE--------EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ-- 496
Query: 212 KKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
K++ ++E++ +++E++ + E + Q + K +EK+ +Q QM+
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK--MWRQEKMREQEDQMW 547
Score = 55.5 bits (132), Expect = 6e-08
Identities = 52/237 (21%), Positives = 120/237 (50%), Gaps = 29/237 (12%)
Query: 34 NSLEQKIRCLEKQRKELLE----VNQQWDQQFRSMKELYER--KVAELKTKLDAAERFLS 87
N+L+++ + +Q +EL E + +Q ++ +R + L E+ K+ E + K+ E+ L
Sbjct: 268 NTLQEE---MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLR 324
Query: 88 TREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTL 147
+EK+ ++++E Q++L Q +E+E++ +E ++E K+ + + L
Sbjct: 325 EQEKELR------EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 378
Query: 148 ANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIY 207
+EK+ E E K ++ + ++ LR+ EE E E + +QV+
Sbjct: 379 WEQEKQMREQEQKMRDQ------EERMWEQDERLREK------EERMREQEKMWEQVEKM 426
Query: 208 EEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMY 264
E+ K+ ++E+ +++EE Q E + + ++ + + + ++EK++KQ + M+
Sbjct: 427 REE--KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 481
Score = 55.5 bits (132), Expect = 6e-08
Identities = 42/244 (17%), Positives = 117/244 (47%), Gaps = 19/244 (7%)
Query: 29 RKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLST 88
++ M E+ +EK R+E Q+ + + K E ++ E + K+ E +
Sbjct: 409 KEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE 468
Query: 89 REKDPHQRQRKDDRQREDDRQRDLTRDRLQREEK---EKERLNEELHELKEENKLLKGKN 145
+E ++ +K + + +++ + RL +++ E+E++ E+ ++ E+ + ++ +
Sbjct: 469 QE----EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524
Query: 146 TLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQ 205
+ +EK+ + E R + + E+ +R + +E R E + +Q+ +
Sbjct: 525 EMWGQEKKMWRQEKMREQED-------QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577
Query: 206 IYEEDFKKERSDR-----ERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQL 260
++++ K +R +++ +E+E +++ E Q Q ++ Q + ++EK+++Q
Sbjct: 578 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE 637
Query: 261 KQMY 264
++M+
Sbjct: 638 EKMW 641
Score = 55.1 bits (131), Expect = 8e-08
Identities = 50/242 (20%), Positives = 119/242 (49%), Gaps = 31/242 (12%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQR 96
EQ+ + E++ K + + WDQ+ E E+K E + K D ++
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQE-----ERMEKKTQEQEKK-----------TWDQEEK 584
Query: 97 QRKDDRQREDDR----QRDLTRDRLQREEKEKERLNEELHEL-KEENKLLKGKNTLANKE 151
R+++R RE ++ + ++ R++ ++ ++++E++ E+ ++ ++E K+ + + + +E
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 152 KEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYE--- 208
++ +E E K + K E + +++ EE E E ++++ Q E
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE-QEEKIWEQEKMEKKTQEQEKKT 703
Query: 209 ---EDFKKERSDRER---LNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
E ++E S RER + +E+E +++ E Q Q ++ Q + ++EK+ +Q ++
Sbjct: 704 WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Query: 263 MY 264
M+
Sbjct: 764 MW 765
Score = 53.5 bits (127), Expect = 2e-07
Identities = 50/253 (19%), Positives = 117/253 (46%), Gaps = 29/253 (11%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQF--RSMKELYERKVAELKTKLDAAERFLSTREKDPH 94
EQ+ + E++ K + + W+QQ ++L+E + + + K+ E + +EK
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694
Query: 95 QRQRKD------DRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLA 148
+ Q ++ ++ RE++ R+ R++ REE+E R EE + ++E K+ + + +
Sbjct: 695 KTQEQEKKTWDQEKMREEESMRE--REKKMREEEEMMREQEEKMQ-EQEEKMQEQEEEMW 751
Query: 149 NKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYE 208
+E++ +E E K + K E + ++ E+MR + E ++ Q +
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 209 EDFKKERSDRERLNQEKEEL------------------QQINETSQSQLNRLNSQIKACQ 250
+K R E++ ++E++ +++ E Q Q ++ Q + +
Sbjct: 812 GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMR 871
Query: 251 MEKEKLEKQLKQM 263
++EK+ +Q ++M
Sbjct: 872 GQEEKMREQEEKM 884
Score = 52.8 bits (125), Expect = 4e-07
Identities = 49/246 (19%), Positives = 120/246 (48%), Gaps = 26/246 (10%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSMKELY---ERKVAELKTKL-DAAERFLSTREKD 92
E+++R EK+ +E E+ ++ +++ + +E E K+ E + K+ + E+ EK
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 93 PHQRQRKDDRQREDDRQRDL-TRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKE 151
Q ++ ++QR +++ L +++Q +EK +E+ + + K E K + + ++E
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707
Query: 152 KEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE---MRTEMEVLKQQVQIYE 208
K E ++ K +++ E+ +R+ + +E E E+ +Q+ +++E
Sbjct: 708 KMREEESMREREKKMRE--------EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Query: 209 EDFK----------KERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEK 258
++ K KE+ QE+E++ + E + Q ++ Q + + ++EK+
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRG 819
Query: 259 QLKQMY 264
Q ++M+
Sbjct: 820 QEEKMW 825
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/258 (22%), Positives = 120/258 (46%), Gaps = 36/258 (13%)
Query: 15 ESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQ-WDQQFRSMKELYERKVA 73
E EH++ E + M E+KI EK K+ E ++ WDQ+ M+E E +
Sbjct: 665 EKLWEHEKMQE----QEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE--KMRE--EESMR 716
Query: 74 ELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEK--EKERLNEEL 131
E + K+ E + RE++ +++++ Q +++ + ++EEK E++RL E+
Sbjct: 717 EREKKMREEEEMM--REQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Query: 132 HELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHE 191
+L E K+ + + +EK + E K E+ +R E
Sbjct: 775 EKLWEHEKMQEQEKIWEQEEKMRDQEE--------------KMRGQEEKMRGQ-----EE 815
Query: 192 EMRTEMEVL-KQQVQIYEEDFKKERSDRERLNQE---KEELQQINETSQSQLNRLNSQIK 247
+MR + E + Q+ +++ ++ K + + QE +E++Q E + Q ++ Q +
Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEE 875
Query: 248 ACQMEKEKLEKQLKQMYC 265
+ ++EK+ Q +++YC
Sbjct: 876 KMREQEEKMRGQEEKIYC 893
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/258 (18%), Positives = 120/258 (46%), Gaps = 29/258 (11%)
Query: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELY----------ERKVAELKTKLDAA 82
M E+K+ E++ E + ++ +Q+ R +E E ++ E + +
Sbjct: 364 MREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQV 423
Query: 83 ERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEEN---- 138
E+ ++ +++ +D ++ + +R R++ REE+E R EE + +EEN
Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 483
Query: 139 --------KLLKGKNTLANKEK-EHYECEIKRLNKALQDALNI----KCSFSEDCLRKSR 185
+L + K L +EK + E +I + ++D + K + ++ +R+
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 186 VEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQ 245
+ +E +M +Q++ EE +K+ ++E+ ++EE + E + + ++ +
Sbjct: 544 DQMWEQE--EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 246 IKACQMEKEKLEKQLKQM 263
+ + ++EK+++Q ++M
Sbjct: 602 EEMMREQEEKMQEQEEKM 619
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/247 (20%), Positives = 125/247 (50%), Gaps = 27/247 (10%)
Query: 25 EPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQ-WDQQFRSMKELYERKVAELKTKLDAAE 83
E +K N EQ+ + E Q++ L E ++ W+Q+ M+E E K+ E + K+ E
Sbjct: 470 EEKMQKQEENMWEQEEK--EWQQQRLPEQKEKLWEQE--KMQE-QEEKIWEQEEKIRDQE 524
Query: 84 RFLSTREKDPHQ---RQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKL 140
+K Q R+++D ++++ RD + +EE+ +++ E+ + ++ +
Sbjct: 525 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK 584
Query: 141 LKGKNTLANKEKEHYECE--IKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE---MRT 195
++ + + +EK+ E E ++ + +Q+ E+ +++ + +E
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQE--------QEEKMQEQEEKMWEQEEKMQEQ 636
Query: 196 EMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEK 255
E ++ +Q+ +++E++ ++ +++RL ++KE+L + +E Q Q + K E+EK
Sbjct: 637 EEKMWEQEEKMWEQE--EKMWEQQRLPEQKEKLWE-HEKMQEQEKMQEQEEKI--WEQEK 691
Query: 256 LEKQLKQ 262
+EK+ ++
Sbjct: 692 MEKKTQE 698
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 58.9 bits (141), Expect = 6e-09
Identities = 49/205 (23%), Positives = 95/205 (46%), Gaps = 36/205 (17%)
Query: 61 FRSMKEL--YERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQ 118
F ++KEL ++ +L+ + + E+ L +E D +++ + + +D+ QR+ T LQ
Sbjct: 329 FSAIKELDTLNNEIVDLQREKNNVEQDLKEKE-DTIKQRTSEVQDLQDEVQRENTN--LQ 385
Query: 119 REEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSE 178
+ + +K+++ E L EL E+ K E ++K + K KC+
Sbjct: 386 KLQAQKQQVQELLDELDEQ--------------KAQLEEQLKEVRK--------KCAEEA 423
Query: 179 DCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQ 238
+ + E +E Q+ YEE+ K R + RL QE EL++ E+ ++Q
Sbjct: 424 QLISSLKAELTSQE---------SQISTYEEELAKAREELSRLQQETAELEESVESGKAQ 474
Query: 239 LNRLNSQIKACQMEKEKLEKQLKQM 263
L L ++ Q E ++ +L +M
Sbjct: 475 LEPLQQHLQDSQQEISSMQMKLMEM 499
Score = 33.5 bits (75), Expect = 0.26
Identities = 46/225 (20%), Positives = 103/225 (45%), Gaps = 32/225 (14%)
Query: 27 STRKNLMNSLE----QKIRCLEKQRKELLEVNQQW---DQQFRSMKELYERKVAELKTKL 79
S +KN++ S I+ L+ E++++ ++ +Q + ++ +++ +E++
Sbjct: 315 SLQKNIIGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQ 374
Query: 80 DAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENK 139
D +R + +K Q+Q+ + E D Q+ ++L+ K+ + + LK E
Sbjct: 375 DEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAE-- 432
Query: 140 LLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEV 199
L ++ ++ E+E L KA ++ ++ +E +E E + ++E
Sbjct: 433 LTSQESQISTYEEE--------LAKAREELSRLQQETAE-------LEESVESGKAQLEP 477
Query: 200 LKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNS 244
L+Q +Q D ++E S + E ++L+ N SQLN +S
Sbjct: 478 LQQHLQ----DSQQEISSMQMKLMEMKDLENHN----SQLNWCSS 514
Score = 31.6 bits (70), Expect = 1.0
Identities = 50/288 (17%), Positives = 114/288 (39%), Gaps = 34/288 (11%)
Query: 5 VQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSM 64
VQ + E++ K A+ + L++ L+++ LE+Q KE+ R
Sbjct: 370 VQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEV-----------RKK 418
Query: 65 KELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEK 124
+ ++ LK +L + E +ST E++ + + + R +++ + + + ++ + +
Sbjct: 419 CAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE---ESVESGKAQL 475
Query: 125 ERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKS 184
E L + L + ++E ++ K + K+ E++ ++ CS L
Sbjct: 476 EPLQQHLQDSQQEISSMQMK-LMEMKDLENHNSQLN------------WCSSPHSILVNG 522
Query: 185 RVEFC-----HEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQL 239
++C E E ++ Q + E +E R + NE + +
Sbjct: 523 ATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVT 582
Query: 240 NRLNSQIKACQMEKEK--LEKQLKQMYCPPCNCGLVFHLQDPWVPTGP 285
++ S++ + KE+ + P + L F DP+V + P
Sbjct: 583 EKVCSELDNNRHSKEEDPFNVDSSSLTGPVADTNLDFFQSDPFVGSDP 630
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 58.9 bits (141), Expect = 6e-09
Identities = 55/243 (22%), Positives = 108/243 (44%), Gaps = 25/243 (10%)
Query: 30 KNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTR 89
K +E ++ +E++ ++LLE +Q ++ EL+ + E++ +L A ++ L
Sbjct: 865 KEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA-EAEEMRARLAAKKQELEEI 923
Query: 90 EKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLAN 149
D R +++ +R Q + EK+++ + +L+E+ +G
Sbjct: 924 LHDLESRVEEEE-------------ERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 150 KEKEHYECEIKRLNKALQDALNIKCSF-SEDCLRKSRVEFCHEEMRTEMEVL-------- 200
EK E +IK++ + + + F E L + R+ C ++ E E
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
Query: 201 KQQVQI--YEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEK 258
KQ+V I EE KKE R+ L + K +L Q Q+ L +QI +++ K E+
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Query: 259 QLK 261
+L+
Sbjct: 1091 ELQ 1093
Score = 54.3 bits (129), Expect = 1e-07
Identities = 56/266 (21%), Positives = 122/266 (45%), Gaps = 31/266 (11%)
Query: 14 AESSTEHKECAEPSTRKNLMNS-LEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKV 72
AE + K A+ ++ +M S LE++++ EK R+EL + ++ D + +++ ++
Sbjct: 1016 AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD----QI 1071
Query: 73 AELKTKLDAAERFLSTREKDPHQR-QRKDDRQREDDRQRDLTRDRLQREEKEKERLNEEL 131
AEL+ ++D + L+ +E++ R DD + + R+ L ++
Sbjct: 1072 AELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRE-----------LQAQI 1120
Query: 132 HELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHE 191
EL+E+ + K A K+K E++ L L+D L+ + ++ K E
Sbjct: 1121 AELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAA-QQELRTKREQEVAEL 1179
Query: 192 EMRTEMEVLKQQVQIYE---------EDFKKERSDRERLNQEKEELQQINETSQSQLN-- 240
+ E E + QI + E+ ++ +R E+ +Q ET +L
Sbjct: 1180 KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACE 1239
Query: 241 -RLNSQIKA-CQMEKEKLEKQLKQMY 264
++ Q+KA + +++KL+ Q+++++
Sbjct: 1240 VKVLQQVKAESEHKRKKLDAQVQELH 1265
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/267 (21%), Positives = 124/267 (46%), Gaps = 39/267 (14%)
Query: 21 KECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKE---LYERKVAELKT 77
+E + TR+ L +L +IR LE+++ L E ++ ++ +++++ + ++A+ K
Sbjct: 1321 QELLQEETRQKL--NLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKK 1378
Query: 78 KLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEE 137
K+D + + E+ + + + + ++ L D+L EK K RL +EL +L +
Sbjct: 1379 KVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKL---EKTKNRLQQELDDLTVD 1435
Query: 138 NKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTE- 196
L + +N EK+ K+ ++ L + +I ++E+ + R E E T+
Sbjct: 1436 --LDHQRQVASNLEKKQ-----KKFDQLLAEEKSISARYAEE---RDRAEAEAREKETKA 1485
Query: 197 ------MEVLKQQVQIYEEDFKKERSDRERLNQEKEE--------------LQQINETSQ 236
+E + + +E K+ R+D E L K++ L+Q E +
Sbjct: 1486 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545
Query: 237 SQLNRLNSQIKACQMEKEKLEKQLKQM 263
+QL L +++A + K +LE ++ M
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQAM 1572
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/226 (24%), Positives = 110/226 (48%), Gaps = 16/226 (7%)
Query: 37 EQKIRCLEKQRKELLEVNQQWDQQFRSM----KELYERKVAELKTKLDAAERFLSTREKD 92
E+K R L KQ +EL E + +++ R++ K+ E + +L+ +++AA + K
Sbjct: 1588 EEKKRLLIKQVREL-EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ 1646
Query: 93 PHQRQRK-DDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKE 151
+ Q + D QRE + R +RD + + KE E+ +L L+ E L+ + + +
Sbjct: 1647 LRKLQAQMKDYQRELEEAR-ASRDEIFAQSKESEK---KLKSLEAEILQLQEELASSERA 1702
Query: 152 KEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDF 211
+ H E E L + ++ + K + ++ K R+E ++ E+E + +++ + F
Sbjct: 1703 RRHAEQERDELADEITNSASGKSALLDE---KRRLEARIAQLEEELEEEQSNMELLNDRF 1759
Query: 212 KKERSDRERLNQE---KEELQQINETSQSQLNRLNSQIKACQMEKE 254
+K + LN E + Q ++ ++ QL R N ++KA E E
Sbjct: 1760 RKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE 1805
Score = 48.9 bits (115), Expect = 6e-06
Identities = 65/278 (23%), Positives = 124/278 (44%), Gaps = 33/278 (11%)
Query: 14 AESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELL----EVNQQWDQQFRSMKEL-- 67
AE+ KE S + L +LE K E+Q K+L ++ D +++ EL
Sbjct: 1474 AEAEAREKETKALSLARALEEALEAKEE-FERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
Query: 68 ----YERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDL-TRDRLQREEK 122
E++V E++T+L+ E L E D R + + + +RDL TRD ++ E+
Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATE-DAKLRLEVNMQAMKAQFERDLQTRD--EQNEE 1589
Query: 123 EKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRL-------NKALQDALN---- 171
+K L +++ EL+ E + + + LA K+ E ++K L NKA + +
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK 1649
Query: 172 IKCSFSE-----DCLRKSRVEFCHEEMRTEMEVLKQQVQIYE--EDFKKERSDRERLNQE 224
++ + + R SR E + +E ++ + +I + E+ R QE
Sbjct: 1650 LQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQE 1709
Query: 225 KEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQ 262
++EL S S + L + + + +LE++L++
Sbjct: 1710 RDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE 1747
Score = 48.9 bits (115), Expect = 6e-06
Identities = 52/263 (19%), Positives = 118/263 (44%), Gaps = 37/263 (14%)
Query: 2 AHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRK---ELLEVNQQWD 58
A +Q + ++E + H E + NS K L+++R+ + ++ ++ +
Sbjct: 1687 AEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELE 1746
Query: 59 QQFRSMKELYER------KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDL 112
++ +M+ L +R +V L +L AAER + Q+ D+ +++ +RQ
Sbjct: 1747 EEQSNMELLNDRFRKTTLQVDTLNAEL-AAERSAA---------QKSDNARQQLERQNKE 1796
Query: 113 TRDRLQREE---KEKER-----LNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNK 164
+ +LQ E K K + L ++ +L+E+ + + ANK E ++K +
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 165 ALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQE 224
++D + E E+ M+ LK+Q++ EE+ + + R +L +E
Sbjct: 1857 QVEDERRHADQYKEQM----------EKANARMKQLKRQLEEAEEEATRANASRRKLQRE 1906
Query: 225 KEELQQINETSQSQLNRLNSQIK 247
++ + NE +++ L ++++
Sbjct: 1907 LDDATEANEGLSREVSTLKNRLR 1929
Score = 47.0 bits (110), Expect = 2e-05
Identities = 50/236 (21%), Positives = 104/236 (44%), Gaps = 20/236 (8%)
Query: 27 STRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFL 86
+ ++ L EQ++ L +K L E + + Q + M++ + + EL +L+ A+RF
Sbjct: 1163 AAQQELRTKREQEVAEL---KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFK 1219
Query: 87 STREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNT 146
+ EK+ +Q + +E + + + E ++++L+ ++ EL +
Sbjct: 1220 ANLEKN---KQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAK--------- 1267
Query: 147 LANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQI 206
E + E+ LQ+ L+ + E+ +K ++F + E ++ Q +
Sbjct: 1268 --VSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG-IKFAKDAASLESQLQDTQELL 1324
Query: 207 YEEDFKK-ERSDRER-LNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQL 260
EE +K S R R L +EK LQ+ E + L Q+ A Q + +K++
Sbjct: 1325 QEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
Score = 45.4 bits (106), Expect = 7e-05
Identities = 37/152 (24%), Positives = 72/152 (47%), Gaps = 18/152 (11%)
Query: 116 RLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCS 175
++ R+E+E + +EEL ++KE+ ++G+ L E++H Q L K
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGE--LEEMERKH------------QQLLEEKNI 891
Query: 176 FSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQ----EKEELQQI 231
+E ++ + EEMR + KQ+++ D + + E NQ EK+++Q
Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
Query: 232 NETSQSQLNRLNSQIKACQMEKEKLEKQLKQM 263
+ + QL+ + Q+EK E ++K+M
Sbjct: 952 IQDLEEQLDEEEGARQKLQLEKVTAEAKIKKM 983
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 58.9 bits (141), Expect = 6e-09
Identities = 52/251 (20%), Positives = 122/251 (48%), Gaps = 36/251 (14%)
Query: 12 IAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERK 71
I++E + +E + S + +E++ +K+R E + +++ R +K ++K
Sbjct: 233 ISSEEPKQEEEREQGSDEISHHEKMEEE----DKERAEAERARLEAEERER-IKAEQDKK 287
Query: 72 VAELKTKLDAAERFLST----REKDPHQRQRKDDRQREDDRQRDLTRDRLQREEK----- 122
+A+ + +++A E+ + RE + +R R+++++ ++RQR ++ EE+
Sbjct: 288 IADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKE 347
Query: 123 EKERLNEELHELKEENKLLKGKNTLAN-KEKEHYECEIKRLNKALQDALNI--------- 172
E++R EE +KEE K + A +E+E + E ++ NK L++ +
Sbjct: 348 EEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE 407
Query: 173 ------------KCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRER 220
+ ED L+ + ++ EE T+++ ++++Q + FKKE E+
Sbjct: 408 KVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEK 467
Query: 221 LNQEKEELQQI 231
+ ++KE +++
Sbjct: 468 IKKDKEPKEEV 478
Score = 58.2 bits (139), Expect = 1e-08
Identities = 62/251 (24%), Positives = 116/251 (46%), Gaps = 17/251 (6%)
Query: 11 MIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYER 70
++ E +TE +E + KN S E+ KQ +E + + + + +E ER
Sbjct: 210 VMVEEKTTESQEETVVMSLKNGQISSEEP-----KQEEEREQGSDEISHHEKMEEEDKER 264
Query: 71 KVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEE 130
AE + +L+A ER E+D ++ D+R R + ++ ++R +RE +E+ER+ EE
Sbjct: 265 AEAE-RARLEAEERERIKAEQD---KKIADERARIEAEEKAAAQERERREAEERERMREE 320
Query: 131 LHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCH 190
EE + +K + A +E++ + E KR A ++ IK + R
Sbjct: 321 EKRAAEERQRIKEEEKRAAEERQRIKEEEKR---AAEERQRIKEEEKRAAEERQRAR-AE 376
Query: 191 EEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQ 250
EE + ++E K+ Q+ E KK ++ EK E Q+I ++ +++
Sbjct: 377 EEEKAKVEEQKRNKQLEE---KKHAMQETKIKGEKVE-QKIEGKWVNEKKAQEDKLQTAV 432
Query: 251 MEKEKLEKQLK 261
++K+ EK K
Sbjct: 433 LKKQGEEKGTK 443
Score = 47.0 bits (110), Expect = 2e-05
Identities = 56/259 (21%), Positives = 111/259 (42%), Gaps = 53/259 (20%)
Query: 13 AAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKV 72
A E+ E KE E K S+ E Q + ++E Q+ + L ++
Sbjct: 180 AEENKKEDKEKEEEEEEKPKRGSIG------ENQVEVMVEEKTTESQEETVVMSLKNGQI 233
Query: 73 AELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELH 132
+ + K + ER + E H++ ++D++R + R RL+ EE+E+ + ++
Sbjct: 234 SSEEPKQEE-EREQGSDEISHHEKMEEEDKERAEAE-----RARLEAEERERIKAEQD-K 286
Query: 133 ELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEE 192
++ +E ++ + A +E+E E E + E
Sbjct: 287 KIADERARIEAEEKAAAQERERREAEER------------------------------ER 316
Query: 193 MRTEMEVLKQQVQIYEEDFKKERSDRERLNQEK----EELQQINE-----TSQSQLNRLN 243
MR E + ++ Q +E+ K+ +R+R+ +E+ EE Q+I E + Q R
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAE 376
Query: 244 SQIKACQMEKEKLEKQLKQ 262
+ KA ++E++K KQL++
Sbjct: 377 EEEKA-KVEEQKRNKQLEE 394
Score = 43.9 bits (102), Expect = 2e-04
Identities = 50/265 (18%), Positives = 115/265 (43%), Gaps = 20/265 (7%)
Query: 19 EHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVA----- 73
E K AE R E+K + E++R + LE + Q+ + E E+K+
Sbjct: 362 EEKRAAEERQRARAEE--EEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN 419
Query: 74 ELKTKLDAAERFLSTR--EKDPHQRQRKDDRQREDD---RQRDLTRDRLQREEKEKERLN 128
E K + D + + + E+ + Q K ++ +ED ++ ++ ++++++++ KE +
Sbjct: 420 EKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK 479
Query: 129 EELHELKEENKLLKGKNTLANKEKEHYECEIKRLN-------KALQDALNIKCSFSEDCL 181
+ K ++ + +H E R K + A ++ + L
Sbjct: 480 SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEEL 539
Query: 182 RKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNR 241
R+ R E EE +++ +Q+ + E+ KK+R +R ++ +E+E+ ++ E +
Sbjct: 540 RRRRGETESEEFE-KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 598
Query: 242 LNSQIKACQMEKEKLEKQLKQMYCP 266
+ ++E+ + E K+ P
Sbjct: 599 EEKRRLKEEIERRRAEAAEKRQKMP 623
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/153 (24%), Positives = 67/153 (43%), Gaps = 18/153 (11%)
Query: 51 LEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQR 110
+E ++ ++ R E + +LK K A L E + +R+ + E+ R++
Sbjct: 530 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAA--LELEELKKKREERRKVLEEEEQRRK 587
Query: 111 DLTRDRLQREEKEKERLNEELHELKEE--NKLLKGKNTLANKEKEHYEC----------- 157
DR REE+EK RL EE+ + E K K + +K+ ++C
Sbjct: 588 QEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIE 647
Query: 158 -EIKRLNKALQDALNIKCSFSEDCLRK--SRVE 187
+ LNK++Q + +K + + K SR+E
Sbjct: 648 ERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLE 680
Score = 30.4 bits (67), Expect = 2.2
Identities = 41/204 (20%), Positives = 80/204 (39%), Gaps = 31/204 (15%)
Query: 79 LDAAERFLSTREKDPHQRQRKDDR---QREDDRQRDLTRDRLQREEKEKERLNEELHELK 135
+D ER R + + + + +R QR DD + + R+R +R +E+ R +E L
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 136 E--ENKLLKGKNTLANKEK------------------EHYECEIKRLNKALQDALNIKCS 175
+ + + +N++ ++E E +R K LQ+AL +
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Query: 176 FSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETS 235
F S + ++ E K+E+S+ + E EE + + ++
Sbjct: 121 FDPTITDAS--------LSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSY 172
Query: 236 QSQLNRLNSQIKACQMEKEKLEKQ 259
Q R + K EKE+ E++
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEEE 196
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,051,512
Number of Sequences: 37866
Number of extensions: 647583
Number of successful extensions: 17250
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 587
Number of HSP's successfully gapped in prelim test: 1005
Number of HSP's that attempted gapping in prelim test: 5058
Number of HSP's gapped (non-prelim): 6225
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.