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Search of human proteins with 192448443
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|192448443 FK506 binding protein 10 [Homo sapiens]
(582 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|192448443 FK506 binding protein 10 [Homo sapiens] 1203 0.0
gi|33469985 FK506 binding protein 9 [Homo sapiens] 685 0.0
gi|8923659 FK506 binding protein 14 [Homo sapiens] 108 2e-23
gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo sapi... 100 6e-21
gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 100 6e-21
gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 100 6e-21
gi|206725547 FK506 binding protein 7 isoform b precursor [Homo s... 92 2e-18
gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo sa... 91 2e-18
gi|31317231 FK506 binding protein 7 isoform a precursor [Homo sa... 89 8e-18
gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo ... 87 6e-17
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 85 2e-16
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 85 2e-16
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 85 2e-16
gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens] 80 7e-15
gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens] 80 7e-15
gi|4503729 FK506 binding protein 52 [Homo sapiens] 79 9e-15
gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo sa... 75 2e-13
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens] 73 6e-13
gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens] 65 1e-10
gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens] 55 1e-07
gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens] 55 1e-07
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 52 2e-06
gi|219842217 FK506 binding protein 11 isoform 2 [Homo sapiens] 45 1e-04
gi|78190478 Kv channel interacting protein 1 isoform 3 [Homo sap... 42 0.002
gi|78190480 Kv channel interacting protein 1 isoform 1 [Homo sap... 42 0.002
gi|7657247 Kv channel interacting protein 1 isoform 2 [Homo sapi... 42 0.002
gi|78190488 Kv channel interacting protein 4 isoform 3 [Homo sap... 41 0.003
gi|78190486 Kv channel interacting protein 4 isoform 5 [Homo sap... 41 0.003
gi|22212902 Kv channel interacting protein 4 isoform 4 [Homo sap... 41 0.003
gi|22212900 Kv channel interacting protein 4 isoform 3 [Homo sap... 41 0.003
>gi|192448443 FK506 binding protein 10 [Homo sapiens]
Length = 582
Score = 1203 bits (3112), Expect = 0.0
Identities = 582/582 (100%), Positives = 582/582 (100%)
Query: 1 MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQ 60
MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQ
Sbjct: 1 MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQ 60
Query: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP
Sbjct: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
Query: 121 PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYH 180
PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYH
Sbjct: 121 PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYH 180
Query: 181 YNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEK 240
YNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEK
Sbjct: 181 YNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEK 240
Query: 241 GYGTVIPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDG 300
GYGTVIPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDG
Sbjct: 241 GYGTVIPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDG 300
Query: 301 TLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPG 360
TLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPG
Sbjct: 301 TLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPG 360
Query: 361 SAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSH 420
SAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSH
Sbjct: 361 SAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSH 420
Query: 421 DYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLLFEV 480
DYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLLFEV
Sbjct: 421 DYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLLFEV 480
Query: 481 ELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRLMPG 540
ELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRLMPG
Sbjct: 481 ELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRLMPG 540
Query: 541 QDPEKTIGDMFQNQDRNQDGKITVDELKLKSDEDEERVHEEL 582
QDPEKTIGDMFQNQDRNQDGKITVDELKLKSDEDEERVHEEL
Sbjct: 541 QDPEKTIGDMFQNQDRNQDGKITVDELKLKSDEDEERVHEEL 582
>gi|33469985 FK506 binding protein 9 [Homo sapiens]
Length = 570
Score = 685 bits (1768), Expect = 0.0
Identities = 331/571 (57%), Positives = 430/571 (75%), Gaps = 15/571 (2%)
Query: 15 PLLQLLLLVVQAVGRGLGRASPAGGPLED--VVIERYHIPRACPREVQMGDFVRYHYNGT 72
PLL LLL V G+A+P G D + IER +P CPR V+ GDFVRYHY GT
Sbjct: 12 PLLLLLLWVT-------GQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGT 64
Query: 73 FEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAG 132
F DG+KFDSSYDR++ + VG G+LITGMD+ L+GMCVNERR + +PP L YG+ G++G
Sbjct: 65 FPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSG 124
Query: 133 LIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFD 192
+IPP++ L+FDV+L+D+WN ED VQ+ T +PP CPR +Q DFVRYHYNGT LDGT FD
Sbjct: 125 VIPPNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFD 184
Query: 193 TSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASL 252
+S+++ TYDTYVG GWLI GMD+GLLGMC GE+R I IPPFLAYGE G G IP QASL
Sbjct: 185 SSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASL 244
Query: 253 VFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHT 312
VF V L+D+HNPKD++ +E +P C R + +GDF+RYHYNG+L+DGTLFDSSYSRN T
Sbjct: 245 VFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRT 304
Query: 313 YNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVID 372
++TYIGQGY+IPGMD+GL G C+GE+RRI +PPHL YGE G G+ IPGSAVL+F++HVID
Sbjct: 305 FDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGN-IPGSAVLVFDIHVID 363
Query: 373 FHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGA 432
FHNP+D + I + +P + C+ +K GD+++YHYN SLLDGT L ++ + G LG+
Sbjct: 364 FHNPSDSISITSHYKPPD-CSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGS 422
Query: 433 NKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARG-VPGSAVLLFEVELVSREDGLPT 491
+V+ G+D GL+ MCVGE+R +I+PPHL +GE+G G VPGSAVL+F++EL+ GLP
Sbjct: 423 GQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVAGLPE 482
Query: 492 GYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRLMPGQDPEKTIGDMF 551
GY+F+W+ + NLFE++D + +GEV EEFS +I AQV+ GKG+L PG D E + +MF
Sbjct: 483 GYMFIWNGEVSPNLFEEIDKDGNGEVLLEEFSEYIHAQVASGKGKLAPGFDAELIVKNMF 542
Query: 552 QNQDRNQDGKITVDELKLKSDEDEERVHEEL 582
NQDRN DGK+T +E KLK D+E H+EL
Sbjct: 543 TNQDRNGDGKVTAEEFKLK---DQEAKHDEL 570
>gi|8923659 FK506 binding protein 14 [Homo sapiens]
Length = 211
Score = 108 bits (269), Expect = 2e-23
Identities = 68/216 (31%), Positives = 111/216 (51%), Gaps = 16/216 (7%)
Query: 361 SAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTS- 419
+ + +F +I P V+I L +P C+ TK GD + HY L LF S
Sbjct: 8 AVLTLFVTSLIGALIPEPEVKIEVLQKPF-ICHRKTKGGDLMLVHYEGYLEKDGSLFHST 66
Query: 420 --HDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLL 477
H+ G P TLG + ++G D GL+GMCVGE+R+LI+PP L +G+ G +P + L+
Sbjct: 67 HKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLI 126
Query: 478 FEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRL 537
F ++L+ +G P + F++MDLN D ++ +E ++K + E G +
Sbjct: 127 FNIDLLEIRNG-PRSH----------ESFQEMDLNDDWKLSKDEVKAYLKKEF-EKHGAV 174
Query: 538 MPGQDPEKTIGDMFQNQDRNQDGKITVDELKLKSDE 573
+ + + D+F +D ++DG I+ E K DE
Sbjct: 175 VNESHHDALVEDIFDKEDEDKDGFISAREFTYKHDE 210
Score = 91.7 bits (226), Expect = 2e-18
Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 4/126 (3%)
Query: 253 VFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSL-MDGTLFDSSYSRNH 311
+F LI P+ V++E L+ P C R+ GD M HY G L DG+LF S++ N+
Sbjct: 12 LFVTSLIGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNN 71
Query: 312 TYNTYIGQGYI--IPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVH 369
+ G + + G DQGL+G C+GE+R++ IPP L YG+ G G KIP + LIFN+
Sbjct: 72 GQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKG-KIPPESTLIFNID 130
Query: 370 VIDFHN 375
+++ N
Sbjct: 131 LLEIRN 136
Score = 87.0 bits (214), Expect = 4e-17
Identities = 48/127 (37%), Positives = 76/127 (59%), Gaps = 5/127 (3%)
Query: 153 EDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTL-LDGTSFDTSYSKGGTYDTYVGSGWL- 210
E V++ L +P C R + GD + HY G L DG+ F +++ + G L
Sbjct: 24 EPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILE 83
Query: 211 -IKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHN-PKDAV 268
+KG DQGL GMC GE+RK+IIPP L YG++G G IPP+++L+F++ L+++ N P+
Sbjct: 84 ALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGK-IPPESTLIFNIDLLEIRNGPRSHE 142
Query: 269 QLETLEL 275
+ ++L
Sbjct: 143 SFQEMDL 149
Score = 86.7 bits (213), Expect = 6e-17
Identities = 49/115 (42%), Positives = 68/115 (59%), Gaps = 4/115 (3%)
Query: 40 PLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFE-DGKKFDSSYDRNTLVAI--VVGVG 96
P +V IE P C R+ + GD + HY G E DG F S++ N I +G+
Sbjct: 23 PEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGIL 82
Query: 97 RLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDVWN 151
+ G D+GL GMCV E+R+LI+PP LGYG G G IPP++TL F++ LL++ N
Sbjct: 83 EALKGWDQGLKGMCVGEKRKLIIPPALGYGKEG-KGKIPPESTLIFNIDLLEIRN 136
>gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
sapiens]
Length = 142
Score = 99.8 bits (247), Expect = 6e-21
Identities = 49/106 (46%), Positives = 66/106 (62%)
Query: 156 VQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMD 215
+Q+ R HCP + GD + HY G L DGT FD+S + + +G+G +IKG D
Sbjct: 31 LQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWD 90
Query: 216 QGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDV 261
QGLLGMC GE+RK++IP L YGE+G IP A+LVF V L+ +
Sbjct: 91 QGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
Score = 93.2 bits (230), Expect = 6e-19
Identities = 43/93 (46%), Positives = 56/93 (60%)
Query: 279 CVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGER 338
C ++ GD + HY G L DGT FDSS +N + +G G +I G DQGL G C GE+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 339 RRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371
R++ IP L YGE G KIPG A L+F V ++
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
Score = 92.4 bits (228), Expect = 1e-18
Identities = 43/95 (45%), Positives = 59/95 (62%)
Query: 55 CPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNER 114
CP + + GD + HY G EDG +FDSS +N +G G++I G D+GL+GMC E+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 115 RRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDV 149
R+L++P LGYG G IP ATL F+V LL +
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
Score = 80.1 bits (196), Expect = 5e-15
Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Query: 392 CNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGER 451
C ++ GD + HY L DGT+ +S P +LG +VI+G D GL GMC GE+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 452 RQLIVPPHLAHGESGA-RGVPGSAVLLFEVELVSRE 486
R+L++P L +GE GA +PG A L+FEVEL+ E
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIE 137
>gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 99.8 bits (247), Expect = 6e-21
Identities = 49/106 (46%), Positives = 66/106 (62%)
Query: 156 VQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMD 215
+Q+ R HCP + GD + HY G L DGT FD+S + + +G+G +IKG D
Sbjct: 31 LQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWD 90
Query: 216 QGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDV 261
QGLLGMC GE+RK++IP L YGE+G IP A+LVF V L+ +
Sbjct: 91 QGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
Score = 93.2 bits (230), Expect = 6e-19
Identities = 43/93 (46%), Positives = 56/93 (60%)
Query: 279 CVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGER 338
C ++ GD + HY G L DGT FDSS +N + +G G +I G DQGL G C GE+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 339 RRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371
R++ IP L YGE G KIPG A L+F V ++
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
Score = 92.4 bits (228), Expect = 1e-18
Identities = 43/95 (45%), Positives = 59/95 (62%)
Query: 55 CPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNER 114
CP + + GD + HY G EDG +FDSS +N +G G++I G D+GL+GMC E+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 115 RRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDV 149
R+L++P LGYG G IP ATL F+V LL +
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
Score = 80.1 bits (196), Expect = 5e-15
Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Query: 392 CNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGER 451
C ++ GD + HY L DGT+ +S P +LG +VI+G D GL GMC GE+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 452 RQLIVPPHLAHGESGA-RGVPGSAVLLFEVELVSRE 486
R+L++P L +GE GA +PG A L+FEVEL+ E
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIE 137
>gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 99.8 bits (247), Expect = 6e-21
Identities = 49/106 (46%), Positives = 66/106 (62%)
Query: 156 VQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMD 215
+Q+ R HCP + GD + HY G L DGT FD+S + + +G+G +IKG D
Sbjct: 31 LQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWD 90
Query: 216 QGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDV 261
QGLLGMC GE+RK++IP L YGE+G IP A+LVF V L+ +
Sbjct: 91 QGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
Score = 93.2 bits (230), Expect = 6e-19
Identities = 43/93 (46%), Positives = 56/93 (60%)
Query: 279 CVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGER 338
C ++ GD + HY G L DGT FDSS +N + +G G +I G DQGL G C GE+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 339 RRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371
R++ IP L YGE G KIPG A L+F V ++
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
Score = 92.4 bits (228), Expect = 1e-18
Identities = 43/95 (45%), Positives = 59/95 (62%)
Query: 55 CPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNER 114
CP + + GD + HY G EDG +FDSS +N +G G++I G D+GL+GMC E+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 115 RRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDV 149
R+L++P LGYG G IP ATL F+V LL +
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
Score = 80.1 bits (196), Expect = 5e-15
Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Query: 392 CNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGER 451
C ++ GD + HY L DGT+ +S P +LG +VI+G D GL GMC GE+
Sbjct: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
Query: 452 RQLIVPPHLAHGESGA-RGVPGSAVLLFEVELVSRE 486
R+L++P L +GE GA +PG A L+FEVEL+ E
Sbjct: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIE 137
>gi|206725547 FK506 binding protein 7 isoform b precursor [Homo
sapiens]
Length = 221
Score = 91.7 bits (226), Expect = 2e-18
Identities = 60/200 (30%), Positives = 105/200 (52%), Gaps = 19/200 (9%)
Query: 380 VEIRTLSRPSETCNETTKLGDFVRYHYNCSLL-DGTQLFTSH--DYGAPQEATLGANKVI 436
V+I L RP E C++T+K GD + HY+ L DG++ + S + G P+ LG +VI
Sbjct: 35 VKIEVLHRP-ENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVI 93
Query: 437 EGLDTGLQGMCVGERRQLIVPPHLAHGESGARG-VPGSAVLLFEVELVSREDGLPTGYLF 495
+GLD + MC GE+R++++PP A+G+ G G +P A L+FE+EL + G
Sbjct: 94 KGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIELYAVTKG------- 146
Query: 496 VWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQV-SEGKGRLMPGQDPEKTIGDMFQNQ 554
F+ +D++ D ++ E + +++ + + K R QD + D+F+
Sbjct: 147 ----PRSIETFKQIDMDNDRQLSKAEINLYLQREFEKDEKPRDKSYQD--AVLEDIFKKN 200
Query: 555 DRNQDGKITVDELKLKSDED 574
D + DG I+ E + ++
Sbjct: 201 DHDGDGFISPKEYNVYQHDE 220
Score = 88.6 bits (218), Expect = 1e-17
Identities = 44/111 (39%), Positives = 69/111 (62%), Gaps = 3/111 (2%)
Query: 154 DTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLL-DGTSFDTSYSKGGTYDTY--VGSGWL 210
+ V++ L RP +C + + GD + HY+G L DG+ F S ++ + + +G G +
Sbjct: 33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQV 92
Query: 211 IKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDV 261
IKG+D + MCPGE+RK++IPP AYG++GY IPP A+L+F + L V
Sbjct: 93 IKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIELYAV 143
Score = 84.3 bits (207), Expect = 3e-16
Identities = 45/111 (40%), Positives = 64/111 (57%), Gaps = 3/111 (2%)
Query: 42 EDVVIERYHIPRACPREVQMGDFVRYHYNGTF-EDGKKFDSSYDRNTLVA--IVVGVGRL 98
E+V IE H P C + + GD + HY+G +DG KF S +N V+GVG++
Sbjct: 33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQV 92
Query: 99 ITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDV 149
I G+D + MC E+R++++PP YG G G IPPDATL F++ L V
Sbjct: 93 IKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIELYAV 143
Score = 77.0 bits (188), Expect = 4e-14
Identities = 39/108 (36%), Positives = 61/108 (56%), Gaps = 3/108 (2%)
Query: 266 DAVQLETLELPPGCVRRAGAGDFMRYHYNGSLM-DGTLFDSSYSRNHTYNTY--IGQGYI 322
+ V++E L P C + + GD + HY+G L DG+ F S ++N + + +G G +
Sbjct: 33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQV 92
Query: 323 IPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHV 370
I G+D + C GE+R++ IPP AYG+ G KIP A LIF + +
Sbjct: 93 IKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIEL 140
>gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo
sapiens]
Length = 201
Score = 91.3 bits (225), Expect = 2e-18
Identities = 46/114 (40%), Positives = 69/114 (60%), Gaps = 2/114 (1%)
Query: 259 IDVHNPKDAVQLETLELPPG-CVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYI 317
++ +P +Q+ETL PP C A GD + HY GSL+DG + D+S +R+ +
Sbjct: 29 LETESPVRTLQVETLVEPPEPCAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRDPLV-IEL 87
Query: 318 GQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371
GQ +IPG++Q L C+GE+RR IP HLAYG+ G +P AV+ ++V +I
Sbjct: 88 GQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELI 141
Score = 87.0 bits (214), Expect = 4e-17
Identities = 54/140 (38%), Positives = 75/140 (53%), Gaps = 6/140 (4%)
Query: 10 SLLRLPLLQLLLL--VVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRY 67
SLL L LL LLLL V GL SP + ++E P C GD +
Sbjct: 6 SLLPLHLLLLLLLSAAVCRAEAGLETESPVRTLQVETLVEP---PEPCAEPAAFGDTLHI 62
Query: 68 HYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGS 127
HY G+ DG+ D+S R+ LV I +G ++I G+++ L+ MCV E+RR I+P HL YG
Sbjct: 63 HYTGSLVDGRIIDTSLTRDPLV-IELGQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGK 121
Query: 128 IGLAGLIPPDATLYFDVVLL 147
G +P DA + +DV L+
Sbjct: 122 RGFPPSVPADAVVQYDVELI 141
Score = 82.8 bits (203), Expect = 8e-16
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 2/115 (1%)
Query: 371 IDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATL 430
++ +P +++ TL P E C E GD + HY SL+DG + TS P L
Sbjct: 29 LETESPVRTLQVETLVEPPEPCAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRD-PLVIEL 87
Query: 431 GANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESG-ARGVPGSAVLLFEVELVS 484
G +VI GL+ L MCVGE+R+ I+P HLA+G+ G VP AV+ ++VEL++
Sbjct: 88 GQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELIA 142
Score = 79.3 bits (194), Expect = 9e-15
Identities = 43/106 (40%), Positives = 62/106 (58%), Gaps = 2/106 (1%)
Query: 155 TVQVSTLLRPPH-CPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKG 213
T+QV TL+ PP C GD + HY G+L+DG DTS ++ +G +I G
Sbjct: 37 TLQVETLVEPPEPCAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRDPLV-IELGQKQVIPG 95
Query: 214 MDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLI 259
++Q LL MC GE+R+ IIP LAYG++G+ +P A + + V LI
Sbjct: 96 LEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELI 141
>gi|31317231 FK506 binding protein 7 isoform a precursor [Homo
sapiens]
Length = 222
Score = 89.4 bits (220), Expect = 8e-18
Identities = 61/201 (30%), Positives = 106/201 (52%), Gaps = 20/201 (9%)
Query: 380 VEIRTLSRPSETCNETTKLGDFVRYHYNCSLL-DGTQLFTSH--DYGAPQEATLGANKVI 436
V+I L RP E C++T+K GD + HY+ L DG++ + S + G P+ LG +VI
Sbjct: 35 VKIEVLHRP-ENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVI 93
Query: 437 EGLDTGLQGMCVGERRQLIVPPHLAHGESG-ARG-VPGSAVLLFEVELVSREDGLPTGYL 494
+GLD + MC GE+R++++PP A+G+ G A G +P A L+FE+EL + G
Sbjct: 94 KGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKG------ 147
Query: 495 FVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQV-SEGKGRLMPGQDPEKTIGDMFQN 553
F+ +D++ D ++ E + +++ + + K R QD + D+F+
Sbjct: 148 -----PRSIETFKQIDMDNDRQLSKAEINLYLQREFEKDEKPRDKSYQD--AVLEDIFKK 200
Query: 554 QDRNQDGKITVDELKLKSDED 574
D + DG I+ E + ++
Sbjct: 201 NDHDGDGFISPKEYNVYQHDE 221
Score = 85.1 bits (209), Expect = 2e-16
Identities = 44/112 (39%), Positives = 69/112 (61%), Gaps = 4/112 (3%)
Query: 154 DTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLL-DGTSFDTSYSKGGTYDTY--VGSGWL 210
+ V++ L RP +C + + GD + HY+G L DG+ F S ++ + + +G G +
Sbjct: 33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQV 92
Query: 211 IKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGT-VIPPQASLVFHVLLIDV 261
IKG+D + MCPGE+RK++IPP AYG++GY IPP A+L+F + L V
Sbjct: 93 IKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAV 144
Score = 81.6 bits (200), Expect = 2e-15
Identities = 46/112 (41%), Positives = 65/112 (58%), Gaps = 4/112 (3%)
Query: 42 EDVVIERYHIPRACPREVQMGDFVRYHYNGTF-EDGKKFDSSYDRNTLVA--IVVGVGRL 98
E+V IE H P C + + GD + HY+G +DG KF S +N V+GVG++
Sbjct: 33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQV 92
Query: 99 ITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLA-GLIPPDATLYFDVVLLDV 149
I G+D + MC E+R++++PP YG G A G IPPDATL F++ L V
Sbjct: 93 IKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAV 144
Score = 74.3 bits (181), Expect = 3e-13
Identities = 39/109 (35%), Positives = 62/109 (56%), Gaps = 4/109 (3%)
Query: 266 DAVQLETLELPPGCVRRAGAGDFMRYHYNGSLM-DGTLFDSSYSRNHTYNTY--IGQGYI 322
+ V++E L P C + + GD + HY+G L DG+ F S ++N + + +G G +
Sbjct: 33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQV 92
Query: 323 IPGMDQGLQGACMGERRRITIPPHLAYGENGTGD-KIPGSAVLIFNVHV 370
I G+D + C GE+R++ IPP AYG+ G + KIP A LIF + +
Sbjct: 93 IKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIEL 141
>gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo
sapiens]
Length = 146
Score = 86.7 bits (213), Expect = 6e-17
Identities = 43/104 (41%), Positives = 63/104 (60%), Gaps = 2/104 (1%)
Query: 259 IDVHNPKDAVQLETLELPPG-CVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYI 317
++ +P +Q+ETL PP C A GD + HY GSL+DG + D+S +R+ +
Sbjct: 29 LETESPVRTLQVETLVEPPEPCAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRDPLV-IEL 87
Query: 318 GQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGS 361
GQ +IPG++Q L C+GE+RR IP HLAYG+ G +PG+
Sbjct: 88 GQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPSVPGT 131
Score = 77.0 bits (188), Expect = 4e-14
Identities = 49/128 (38%), Positives = 67/128 (52%), Gaps = 6/128 (4%)
Query: 10 SLLRLPLLQLLLL--VVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRY 67
SLL L LL LLLL V GL SP + ++E P C GD +
Sbjct: 6 SLLPLHLLLLLLLSAAVCRAEAGLETESPVRTLQVETLVEP---PEPCAEPAAFGDTLHI 62
Query: 68 HYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGS 127
HY G+ DG+ D+S R+ LV I +G ++I G+++ L+ MCV E+RR I+P HL YG
Sbjct: 63 HYTGSLVDGRIIDTSLTRDPLV-IELGQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGK 121
Query: 128 IGLAGLIP 135
G +P
Sbjct: 122 RGFPPSVP 129
Score = 75.1 bits (183), Expect = 2e-13
Identities = 39/94 (41%), Positives = 56/94 (59%), Gaps = 2/94 (2%)
Query: 155 TVQVSTLLRPPH-CPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKG 213
T+QV TL+ PP C GD + HY G+L+DG DTS ++ +G +I G
Sbjct: 37 TLQVETLVEPPEPCAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRDPLV-IELGQKQVIPG 95
Query: 214 MDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIP 247
++Q LL MC GE+R+ IIP LAYG++G+ +P
Sbjct: 96 LEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPSVP 129
Score = 74.3 bits (181), Expect = 3e-13
Identities = 41/104 (39%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Query: 371 IDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATL 430
++ +P +++ TL P E C E GD + HY SL+DG + TS P L
Sbjct: 29 LETESPVRTLQVETLVEPPEPCAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRD-PLVIEL 87
Query: 431 GANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESG-ARGVPGS 473
G +VI GL+ L MCVGE+R+ I+P HLA+G+ G VPG+
Sbjct: 88 GQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPSVPGT 131
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 85.1 bits (209), Expect = 2e-16
Identities = 69/225 (30%), Positives = 102/225 (45%), Gaps = 21/225 (9%)
Query: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
+GD V HY G +GKKFDSS+DRN +G G++I D G+ M E L+
Sbjct: 49 IGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCK 108
Query: 121 PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNK---EDTVQVSTLLRPPHCPRMVQDGDFV 177
P YGS G IP +ATL+F++ LLD + ED + R +G V
Sbjct: 109 PEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATV 168
Query: 178 RYHYNGTLLDGTSFDT-----SYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIP 232
H G G FD + +G +D + G+D+ L M E+ + +
Sbjct: 169 EIHLEGR-CGGRMFDCRDVAFTVGEGEDHDIPI-------GIDKALEKMQREEQCILYLG 220
Query: 233 PFLAYGEKG---YGTVIPPQASLVFHVLLIDVHNPKDAVQLETLE 274
P +GE G +G I P A L++ V L K++ +++T E
Sbjct: 221 PRYGFGEAGKPKFG--IEPNAELIYEVTLKSFEKAKESWEMDTKE 263
Score = 77.8 bits (190), Expect = 3e-14
Identities = 74/267 (27%), Positives = 114/267 (42%), Gaps = 22/267 (8%)
Query: 260 DVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQ 319
D+ + KD L+ ++ GD + HY G L +G FDSS+ RN + +G+
Sbjct: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
Query: 320 GYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADV 379
G +I D G+ GE + P AYG G+ KIP +A L F + ++DF D+
Sbjct: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG-EDL 142
Query: 380 VE----IRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANK- 434
E IR R E + + G V H G ++F D T+G +
Sbjct: 143 FEDGGIIRRTKRKGEGYSNPNE-GATVEIHLEGRC--GGRMFDCRDVA----FTVGEGED 195
Query: 435 --VIEGLDTGLQGMCVGERRQLIVPPHLAHGESGAR--GVPGSAVLLFEVELVSREDGLP 490
+ G+D L+ M E+ L + P GE+G G+ +A L++EV L S E
Sbjct: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255
Query: 491 TGYLFVWHKDPPANLFEDMDLNKDGEV 517
+ W D L + + + G V
Sbjct: 256 S-----WEMDTKEKLEQAAIVKEKGTV 277
Score = 69.7 bits (169), Expect = 7e-12
Identities = 67/249 (26%), Positives = 105/249 (42%), Gaps = 23/249 (9%)
Query: 148 DVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGS 207
D+ +K+D + + R + GD V HY G L +G FD+S+ + + +G
Sbjct: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
Query: 208 GWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDA 267
G +IK D G+ M GE ++ P AYG G IP A+L F + L+D
Sbjct: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG---- 139
Query: 268 VQLETLELPPGCVRRA----------GAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYI 317
E L G +RR G + H G G +FD R+ +
Sbjct: 140 ---EDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFD---CRDVAFTVGE 192
Query: 318 GQGYIIP-GMDQGLQGACMGERRRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVIDFHN 375
G+ + IP G+D+ L+ E+ + + P +GE G I +A LI+ V + F
Sbjct: 193 GEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK 252
Query: 376 PADVVEIRT 384
+ E+ T
Sbjct: 253 AKESWEMDT 261
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 85.1 bits (209), Expect = 2e-16
Identities = 69/225 (30%), Positives = 102/225 (45%), Gaps = 21/225 (9%)
Query: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
+GD V HY G +GKKFDSS+DRN +G G++I D G+ M E L+
Sbjct: 49 IGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCK 108
Query: 121 PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNK---EDTVQVSTLLRPPHCPRMVQDGDFV 177
P YGS G IP +ATL+F++ LLD + ED + R +G V
Sbjct: 109 PEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATV 168
Query: 178 RYHYNGTLLDGTSFDT-----SYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIP 232
H G G FD + +G +D + G+D+ L M E+ + +
Sbjct: 169 EIHLEGR-CGGRMFDCRDVAFTVGEGEDHDIPI-------GIDKALEKMQREEQCILYLG 220
Query: 233 PFLAYGEKG---YGTVIPPQASLVFHVLLIDVHNPKDAVQLETLE 274
P +GE G +G I P A L++ V L K++ +++T E
Sbjct: 221 PRYGFGEAGKPKFG--IEPNAELIYEVTLKSFEKAKESWEMDTKE 263
Score = 77.8 bits (190), Expect = 3e-14
Identities = 74/267 (27%), Positives = 114/267 (42%), Gaps = 22/267 (8%)
Query: 260 DVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQ 319
D+ + KD L+ ++ GD + HY G L +G FDSS+ RN + +G+
Sbjct: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
Query: 320 GYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADV 379
G +I D G+ GE + P AYG G+ KIP +A L F + ++DF D+
Sbjct: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG-EDL 142
Query: 380 VE----IRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANK- 434
E IR R E + + G V H G ++F D T+G +
Sbjct: 143 FEDGGIIRRTKRKGEGYSNPNE-GATVEIHLEGRC--GGRMFDCRDVA----FTVGEGED 195
Query: 435 --VIEGLDTGLQGMCVGERRQLIVPPHLAHGESGAR--GVPGSAVLLFEVELVSREDGLP 490
+ G+D L+ M E+ L + P GE+G G+ +A L++EV L S E
Sbjct: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255
Query: 491 TGYLFVWHKDPPANLFEDMDLNKDGEV 517
+ W D L + + + G V
Sbjct: 256 S-----WEMDTKEKLEQAAIVKEKGTV 277
Score = 69.7 bits (169), Expect = 7e-12
Identities = 67/249 (26%), Positives = 105/249 (42%), Gaps = 23/249 (9%)
Query: 148 DVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGS 207
D+ +K+D + + R + GD V HY G L +G FD+S+ + + +G
Sbjct: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
Query: 208 GWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDA 267
G +IK D G+ M GE ++ P AYG G IP A+L F + L+D
Sbjct: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG---- 139
Query: 268 VQLETLELPPGCVRRA----------GAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYI 317
E L G +RR G + H G G +FD R+ +
Sbjct: 140 ---EDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFD---CRDVAFTVGE 192
Query: 318 GQGYIIP-GMDQGLQGACMGERRRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVIDFHN 375
G+ + IP G+D+ L+ E+ + + P +GE G I +A LI+ V + F
Sbjct: 193 GEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK 252
Query: 376 PADVVEIRT 384
+ E+ T
Sbjct: 253 AKESWEMDT 261
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 85.1 bits (209), Expect = 2e-16
Identities = 69/225 (30%), Positives = 102/225 (45%), Gaps = 21/225 (9%)
Query: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
+GD V HY G +GKKFDSS+DRN +G G++I D G+ M E L+
Sbjct: 49 IGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCK 108
Query: 121 PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNK---EDTVQVSTLLRPPHCPRMVQDGDFV 177
P YGS G IP +ATL+F++ LLD + ED + R +G V
Sbjct: 109 PEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATV 168
Query: 178 RYHYNGTLLDGTSFDT-----SYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIP 232
H G G FD + +G +D + G+D+ L M E+ + +
Sbjct: 169 EIHLEGR-CGGRMFDCRDVAFTVGEGEDHDIPI-------GIDKALEKMQREEQCILYLG 220
Query: 233 PFLAYGEKG---YGTVIPPQASLVFHVLLIDVHNPKDAVQLETLE 274
P +GE G +G I P A L++ V L K++ +++T E
Sbjct: 221 PRYGFGEAGKPKFG--IEPNAELIYEVTLKSFEKAKESWEMDTKE 263
Score = 77.8 bits (190), Expect = 3e-14
Identities = 74/267 (27%), Positives = 114/267 (42%), Gaps = 22/267 (8%)
Query: 260 DVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQ 319
D+ + KD L+ ++ GD + HY G L +G FDSS+ RN + +G+
Sbjct: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
Query: 320 GYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADV 379
G +I D G+ GE + P AYG G+ KIP +A L F + ++DF D+
Sbjct: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG-EDL 142
Query: 380 VE----IRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANK- 434
E IR R E + + G V H G ++F D T+G +
Sbjct: 143 FEDGGIIRRTKRKGEGYSNPNE-GATVEIHLEGRC--GGRMFDCRDVA----FTVGEGED 195
Query: 435 --VIEGLDTGLQGMCVGERRQLIVPPHLAHGESGAR--GVPGSAVLLFEVELVSREDGLP 490
+ G+D L+ M E+ L + P GE+G G+ +A L++EV L S E
Sbjct: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255
Query: 491 TGYLFVWHKDPPANLFEDMDLNKDGEV 517
+ W D L + + + G V
Sbjct: 256 S-----WEMDTKEKLEQAAIVKEKGTV 277
Score = 69.7 bits (169), Expect = 7e-12
Identities = 67/249 (26%), Positives = 105/249 (42%), Gaps = 23/249 (9%)
Query: 148 DVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGS 207
D+ +K+D + + R + GD V HY G L +G FD+S+ + + +G
Sbjct: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
Query: 208 GWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDA 267
G +IK D G+ M GE ++ P AYG G IP A+L F + L+D
Sbjct: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG---- 139
Query: 268 VQLETLELPPGCVRRA----------GAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYI 317
E L G +RR G + H G G +FD R+ +
Sbjct: 140 ---EDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFD---CRDVAFTVGE 192
Query: 318 GQGYIIP-GMDQGLQGACMGERRRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVIDFHN 375
G+ + IP G+D+ L+ E+ + + P +GE G I +A LI+ V + F
Sbjct: 193 GEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK 252
Query: 376 PADVVEIRT 384
+ E+ T
Sbjct: 253 AKESWEMDT 261
>gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 79.7 bits (195), Expect = 7e-15
Identities = 39/80 (48%), Positives = 49/80 (61%)
Query: 68 HYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGS 127
HY G EDGKKFDSS DRN ++G +I G + G+ M V +R +L + P YG+
Sbjct: 26 HYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGA 85
Query: 128 IGLAGLIPPDATLYFDVVLL 147
G G+IPP ATL FDV LL
Sbjct: 86 TGHPGIIPPHATLVFDVELL 105
Score = 65.9 bits (159), Expect = 1e-10
Identities = 38/104 (36%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 156 VQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMD 215
VQV T+ P + G HY G L DG FD+S + + +G +I+G +
Sbjct: 3 VQVETI-SPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWE 61
Query: 216 QGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLI 259
+G+ M G+R K+ I P AYG G+ +IPP A+LVF V L+
Sbjct: 62 EGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL 105
Score = 65.9 bits (159), Expect = 1e-10
Identities = 39/105 (37%), Positives = 56/105 (53%), Gaps = 3/105 (2%)
Query: 268 VQLETLELPPGCVRR-AGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGM 326
VQ+ET+ PG R G HY G L DG FDSS RN + +G+ +I G
Sbjct: 3 VQVETIS--PGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW 60
Query: 327 DQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371
++G+ +G+R ++TI P AYG G IP A L+F+V ++
Sbjct: 61 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL 105
Score = 58.5 bits (140), Expect = 2e-08
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 397 KLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIV 456
K G HY L DG + +S D P + LG +VI G + G+ M VG+R +L +
Sbjct: 18 KRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTI 77
Query: 457 PPHLAHGESGARG-VPGSAVLLFEVELVSRE 486
P A+G +G G +P A L+F+VEL+ E
Sbjct: 78 SPDYAYGATGHPGIIPPHATLVFDVELLKLE 108
>gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 79.7 bits (195), Expect = 7e-15
Identities = 39/80 (48%), Positives = 49/80 (61%)
Query: 68 HYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGS 127
HY G EDGKKFDSS DRN ++G +I G + G+ M V +R +L + P YG+
Sbjct: 26 HYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGA 85
Query: 128 IGLAGLIPPDATLYFDVVLL 147
G G+IPP ATL FDV LL
Sbjct: 86 TGHPGIIPPHATLVFDVELL 105
Score = 65.9 bits (159), Expect = 1e-10
Identities = 38/104 (36%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 156 VQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMD 215
VQV T+ P + G HY G L DG FD+S + + +G +I+G +
Sbjct: 3 VQVETI-SPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWE 61
Query: 216 QGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLI 259
+G+ M G+R K+ I P AYG G+ +IPP A+LVF V L+
Sbjct: 62 EGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL 105
Score = 65.9 bits (159), Expect = 1e-10
Identities = 39/105 (37%), Positives = 56/105 (53%), Gaps = 3/105 (2%)
Query: 268 VQLETLELPPGCVRR-AGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGM 326
VQ+ET+ PG R G HY G L DG FDSS RN + +G+ +I G
Sbjct: 3 VQVETIS--PGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW 60
Query: 327 DQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371
++G+ +G+R ++TI P AYG G IP A L+F+V ++
Sbjct: 61 EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL 105
Score = 58.5 bits (140), Expect = 2e-08
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 397 KLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIV 456
K G HY L DG + +S D P + LG +VI G + G+ M VG+R +L +
Sbjct: 18 KRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTI 77
Query: 457 PPHLAHGESGARG-VPGSAVLLFEVELVSRE 486
P A+G +G G +P A L+F+VEL+ E
Sbjct: 78 SPDYAYGATGHPGIIPPHATLVFDVELLKLE 108
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 79.3 bits (194), Expect = 9e-15
Identities = 68/245 (27%), Positives = 105/245 (42%), Gaps = 11/245 (4%)
Query: 147 LDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVG 206
+D+ K+D + + R M GD V HY G LLDGT FD+S + + +G
Sbjct: 23 VDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLG 82
Query: 207 SGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLI-----DV 261
G +IK D + M GE I P AYG G IPP A+LVF V L D+
Sbjct: 83 KGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDL 142
Query: 262 HNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGY 321
+D + ++ + G + G D LFD R + G+
Sbjct: 143 TEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD-KLFD---QRELRFEIGEGENL 198
Query: 322 IIP-GMDQGLQGACMGERRRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVIDFHNPADV 379
+P G+++ +Q GE + + P A+G G +IP +A L + +H+ F +
Sbjct: 199 DLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKES 258
Query: 380 VEIRT 384
E+ +
Sbjct: 259 WEMNS 263
Score = 76.6 bits (187), Expect = 6e-14
Identities = 67/239 (28%), Positives = 103/239 (43%), Gaps = 19/239 (7%)
Query: 259 IDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIG 318
+D+ +D L+ ++ GD + HY G L+DGT FDSS R ++ +G
Sbjct: 23 VDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLG 82
Query: 319 QGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPAD 378
+G +I D + +GE IT P AYG G+ KIP +A L+F V + +F D
Sbjct: 83 KGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKG-ED 141
Query: 379 VVE---------IRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEAT 429
+ E I+T NE + + +Y L D +L + G +
Sbjct: 142 LTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQREL--RFEIGEGENLD 199
Query: 430 LGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGAR--GVPGSAVLLFEVELVSRE 486
L GL+ +Q M GE + + P A G G +P +A L +E+ L S E
Sbjct: 200 LP-----YGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFE 253
Score = 75.1 bits (183), Expect = 2e-13
Identities = 63/224 (28%), Positives = 92/224 (41%), Gaps = 17/224 (7%)
Query: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
+GD V HY G DG KFDSS DR + +G G +I D + M V E +
Sbjct: 49 IGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCK 108
Query: 121 PHLGYGSIGLAGLIPPDATLYFDVVLL-----DVWNKEDTVQVSTLLRPPHCPRMVQDGD 175
P YGS G IPP+ATL F+V L D+ +ED + + +G
Sbjct: 109 PEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGA 168
Query: 176 FVRY----HYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIII 231
V +Y L D +G D L G+++ + M GE + +
Sbjct: 169 IVEVALEGYYKDKLFDQRELRFEIGEGENLD-------LPYGLERAIQRMEKGEHSIVYL 221
Query: 232 PPFLAYGEKGYGTV-IPPQASLVFHVLLIDVHNPKDAVQLETLE 274
P A+G G IPP A L + + L K++ ++ + E
Sbjct: 222 KPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEE 265
>gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo
sapiens]
Length = 108
Score = 74.7 bits (182), Expect = 2e-13
Identities = 36/82 (43%), Positives = 50/82 (60%)
Query: 68 HYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGS 127
HY G ++GKKFDSS DRN +G +I G + G M + +R +L P + YG+
Sbjct: 26 HYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGA 85
Query: 128 IGLAGLIPPDATLYFDVVLLDV 149
G G+IPP+ATL FDV LL++
Sbjct: 86 TGHPGVIPPNATLIFDVELLNL 107
Score = 65.5 bits (158), Expect = 1e-10
Identities = 38/106 (35%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Query: 268 VQLETLELPPGCVRR-AGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGM 326
V++ET+ PG R G HY G L +G FDSS RN + IG+ +I G
Sbjct: 3 VEIETIS--PGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60
Query: 327 DQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVID 372
++G +G+R ++T P +AYG G IP +A LIF+V +++
Sbjct: 61 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLN 106
Score = 64.3 bits (155), Expect = 3e-10
Identities = 31/82 (37%), Positives = 48/82 (58%)
Query: 180 HYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGE 239
HY G L +G FD+S + + +G +IKG ++G M G+R K+ P +AYG
Sbjct: 26 HYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGA 85
Query: 240 KGYGTVIPPQASLVFHVLLIDV 261
G+ VIPP A+L+F V L+++
Sbjct: 86 TGHPGVIPPNATLIFDVELLNL 107
Score = 57.8 bits (138), Expect = 3e-08
Identities = 38/108 (35%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Query: 380 VEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGL 439
VEI T+S P + K G HY L +G + +S D P + +G +VI+G
Sbjct: 3 VEIETIS-PGDG-RTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60
Query: 440 DTGLQGMCVGERRQLIVPPHLAHGESGARGV-PGSAVLLFEVELVSRE 486
+ G M +G+R +L P +A+G +G GV P +A L+F+VEL++ E
Sbjct: 61 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 108
>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
Length = 268
Score = 73.2 bits (178), Expect = 6e-13
Identities = 41/103 (39%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Query: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
+GD V HY G +GKKFDSS+DRN +G G++I D G+ M E L+
Sbjct: 49 IGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCK 108
Query: 121 PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLR 163
P YGS G IP +ATL+F++ LLD + ED + ++R
Sbjct: 109 PEYAYGSAGSLPKIPSNATLFFEIELLD-FKGEDLFEDGGIIR 150
Score = 66.6 bits (161), Expect = 6e-11
Identities = 37/114 (32%), Positives = 56/114 (49%)
Query: 260 DVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQ 319
D+ + KD L+ ++ GD + HY G L +G FDSS+ RN + +G+
Sbjct: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
Query: 320 GYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDF 373
G +I D G+ GE + P AYG G+ KIP +A L F + ++DF
Sbjct: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137
Score = 61.2 bits (147), Expect = 2e-09
Identities = 54/195 (27%), Positives = 83/195 (42%), Gaps = 22/195 (11%)
Query: 148 DVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGS 207
D+ +K+D + + R + GD V HY G L +G FD+S+ + + +G
Sbjct: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
Query: 208 GWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDA 267
G +IK D G+ M GE ++ P AYG G IP A+L F + L+D
Sbjct: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG---- 139
Query: 268 VQLETLELPPGCVRRA----------GAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYI 317
E L G +RR G + H G G +FD R+ +
Sbjct: 140 ---EDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFD---CRDVAFTVGE 192
Query: 318 GQGYIIP-GMDQGLQ 331
G+ + IP G+D+ L+
Sbjct: 193 GEDHDIPIGIDKALE 207
Score = 60.1 bits (144), Expect = 6e-09
Identities = 52/190 (27%), Positives = 83/190 (43%), Gaps = 27/190 (14%)
Query: 394 ETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQ 453
ET +GD V HY L +G + +SHD P +LG +VI+ D G+ M GE
Sbjct: 45 ETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICH 104
Query: 454 LIVPPHLAHGESGA-RGVPGSAVLLFEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLN 512
L+ P A+G +G+ +P +A L FE+EL+ + +LFED +
Sbjct: 105 LLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG---------------EDLFEDGGII 149
Query: 513 K------DGEVPPEEFSTFIKAQVSEGKGRLMPGQDPEKTIGDMFQNQDRNQDGKITVDE 566
+ +G P E +T GR+ +D T+G + + D I +D+
Sbjct: 150 RRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVG-----EGEDHDIPIGIDK 204
Query: 567 LKLKSDEDEE 576
K +E+
Sbjct: 205 ALEKMQREEQ 214
>gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
Length = 224
Score = 65.5 bits (158), Expect = 1e-10
Identities = 40/96 (41%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
Query: 174 GDFVRYHYNGTLLDGTSFDTSYSKGGT-------YDTYVGSGWLIKGMDQGLLGMCPGER 226
GD V Y GTL DGT FDT+ VG G +I+G D+ LL M GE+
Sbjct: 128 GDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEK 187
Query: 227 RKIIIPPFLAYGEKGY-GTVIPPQASLVFHVLLIDV 261
++ I P AYG+KG IPP A L F V L+D+
Sbjct: 188 ARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDI 223
Score = 59.3 bits (142), Expect = 9e-09
Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
Query: 62 GDFVRYHYNGTFEDGKKFDSSYDRNTL-------VAIVVGVGRLITGMDRGLMGMCVNER 114
GD V Y GT +DG FD++ + ++ VGVG++I G D L+ M E+
Sbjct: 128 GDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEK 187
Query: 115 RRLIVPPHLGYGSIGLA-GLIPPDATLYFDVVLLDV 149
RL + P YG G IPP+A L F+V L+D+
Sbjct: 188 ARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDI 223
Score = 58.5 bits (140), Expect = 2e-08
Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Query: 286 GDFMRYHYNGSLMDGTLFDSSYSRN-------HTYNTYIGQGYIIPGMDQGLQGACMGER 338
GD + Y G+L DGT+FD++ + + +G G +I G D+ L GE+
Sbjct: 128 GDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEK 187
Query: 339 RRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVID 372
R+ I P AYG+ G D KIP +A L F V ++D
Sbjct: 188 ARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVD 222
Score = 50.1 bits (118), Expect = 6e-06
Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 9/96 (9%)
Query: 397 KLGDFVRYHYNCSLLDGTQLFTSHDYGA-------PQEATLGANKVIEGLDTGLQGMCVG 449
K GD V Y +L DGT T+ A P +G KVI G D L M G
Sbjct: 126 KKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKG 185
Query: 450 ERRQLIVPPHLAHGESGA--RGVPGSAVLLFEVELV 483
E+ +L + P A+G+ G +P +A L FEVELV
Sbjct: 186 EKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELV 221
>gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]
Length = 322
Score = 55.5 bits (132), Expect = 1e-07
Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 69 YNGTFED-GKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGS 127
Y+G E + FDS+Y R T + +G + GM+ GL+ M E R + P+ YG+
Sbjct: 56 YSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGT 115
Query: 128 IGLAGLIPPDATLYFDVVLLD 148
+G LIPP+ T+ F++ LLD
Sbjct: 116 LGCPPLIPPNTTVLFEIELLD 136
Score = 47.8 bits (112), Expect = 3e-05
Identities = 37/115 (32%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 280 VRRAGAGDFMR------YHYNGSL--MDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQ 331
V R GAGD + Y+G L MD FDS+Y R +G+ + GM+ GL
Sbjct: 37 VIREGAGDLVAPDASVLVKYSGYLEHMDRP-FDSNYFRKTPRLMKLGEDITLWGMELGLL 95
Query: 332 GACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADVVEIRTLS 386
GE R P+ AYG G IP + ++F + ++DF + A+ + LS
Sbjct: 96 SMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALS 150
Score = 43.9 bits (102), Expect = 4e-04
Identities = 23/70 (32%), Positives = 37/70 (52%)
Query: 191 FDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQA 250
FD++Y + +G + GM+ GLL M GE + + P AYG G +IPP
Sbjct: 67 FDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNT 126
Query: 251 SLVFHVLLID 260
+++F + L+D
Sbjct: 127 TVLFEIELLD 136
>gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]
Length = 327
Score = 55.5 bits (132), Expect = 1e-07
Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 69 YNGTFED-GKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGS 127
Y+G E + FDS+Y R T + +G + GM+ GL+ M E R + P+ YG+
Sbjct: 61 YSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGT 120
Query: 128 IGLAGLIPPDATLYFDVVLLD 148
+G LIPP+ T+ F++ LLD
Sbjct: 121 LGCPPLIPPNTTVLFEIELLD 141
Score = 47.8 bits (112), Expect = 3e-05
Identities = 37/115 (32%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 280 VRRAGAGDFMR------YHYNGSL--MDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQ 331
V R GAGD + Y+G L MD FDS+Y R +G+ + GM+ GL
Sbjct: 42 VIREGAGDLVAPDASVLVKYSGYLEHMDRP-FDSNYFRKTPRLMKLGEDITLWGMELGLL 100
Query: 332 GACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADVVEIRTLS 386
GE R P+ AYG G IP + ++F + ++DF + A+ + LS
Sbjct: 101 SMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALS 155
Score = 43.9 bits (102), Expect = 4e-04
Identities = 23/70 (32%), Positives = 37/70 (52%)
Query: 191 FDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQA 250
FD++Y + +G + GM+ GLL M GE + + P AYG G +IPP
Sbjct: 72 FDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNT 131
Query: 251 SLVFHVLLID 260
+++F + L+D
Sbjct: 132 TVLFEIELLD 141
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/91 (35%), Positives = 54/91 (59%), Gaps = 5/91 (5%)
Query: 59 VQMGDFVRYHYNG-TFED---GKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNER 114
V++GD + Y G F++ G+ FDS+ +++ L+ + +G G++I G + G++GM +
Sbjct: 194 VEVGDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGK 253
Query: 115 RRLIVPPHLGYGSIGLAGLI-PPDATLYFDV 144
R LIVPP GS G+ G D+ L F+V
Sbjct: 254 RLLIVPPACAVGSEGVIGWTQATDSILVFEV 284
Score = 51.2 bits (121), Expect = 3e-06
Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 5/102 (4%)
Query: 171 VQDGDFVRYHYNGTLLD----GTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGER 226
V+ GD + Y G L G FD++ +K +GSG +IKG + G+LGM G +
Sbjct: 194 VEVGDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGK 253
Query: 227 RKIIIPPFLAYGEKG-YGTVIPPQASLVFHVLLIDVHNPKDA 267
R +I+PP A G +G G + LVF V + V +D+
Sbjct: 254 RLLIVPPACAVGSEGVIGWTQATDSILVFEVEVRRVKFARDS 295
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 5/90 (5%)
Query: 286 GDFMRYHYNGSLMD----GTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRI 341
GD + Y G L G +FDS+ +++ +G G +I G + G+ G G +R +
Sbjct: 197 GDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLL 256
Query: 342 TIPPHLAYGENGT-GDKIPGSAVLIFNVHV 370
+PP A G G G ++L+F V V
Sbjct: 257 IVPPACAVGSEGVIGWTQATDSILVFEVEV 286
Score = 44.3 bits (103), Expect = 3e-04
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 12/79 (15%)
Query: 416 LFTSHDYGAPQEAT----------LGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGES 465
LF +H G ++T LG+ KVI+G + G+ GM G +R LIVPP A G
Sbjct: 208 LFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLLIVPPACAVGSE 267
Query: 466 GARG--VPGSAVLLFEVEL 482
G G ++L+FEVE+
Sbjct: 268 GVIGWTQATDSILVFEVEV 286
>gi|219842217 FK506 binding protein 11 isoform 2 [Homo sapiens]
Length = 99
Score = 45.4 bits (106), Expect = 1e-04
Identities = 19/39 (48%), Positives = 25/39 (64%)
Query: 109 MCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLL 147
MCV E+RR I+P HL YG G +P DA + +DV L+
Sbjct: 1 MCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELI 39
Score = 44.7 bits (104), Expect = 2e-04
Identities = 20/40 (50%), Positives = 30/40 (75%), Gaps = 1/40 (2%)
Query: 446 MCVGERRQLIVPPHLAHGESG-ARGVPGSAVLLFEVELVS 484
MCVGE+R+ I+P HLA+G+ G VP AV+ ++VEL++
Sbjct: 1 MCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELIA 40
Score = 43.5 bits (101), Expect = 5e-04
Identities = 18/38 (47%), Positives = 26/38 (68%)
Query: 334 CMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371
C+GE+RR IP HLAYG+ G +P AV+ ++V +I
Sbjct: 2 CVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELI 39
Score = 40.4 bits (93), Expect = 0.005
Identities = 18/39 (46%), Positives = 26/39 (66%)
Query: 221 MCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLI 259
MC GE+R+ IIP LAYG++G+ +P A + + V LI
Sbjct: 1 MCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELI 39
>gi|78190478 Kv channel interacting protein 1 isoform 3 [Homo
sapiens]
Length = 225
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 506 FEDMDLNKDGEVPPEEFSTFIKAQVSEGKGR----LMPGQDPEKTIGDMFQNQDRNQDGK 561
F D+NKDG + EE +KA + + G+ ++ P + + FQ D+N+DG
Sbjct: 140 FNLYDINKDGYINKEEMMDIVKA-IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGI 198
Query: 562 ITVDELKLKSDEDE 575
+T+DE ED+
Sbjct: 199 VTLDEFLESCQEDD 212
>gi|78190480 Kv channel interacting protein 1 isoform 1 [Homo
sapiens]
Length = 227
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 506 FEDMDLNKDGEVPPEEFSTFIKAQVSEGKGR----LMPGQDPEKTIGDMFQNQDRNQDGK 561
F D+NKDG + EE +KA + + G+ ++ P + + FQ D+N+DG
Sbjct: 142 FNLYDINKDGYINKEEMMDIVKA-IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGI 200
Query: 562 ITVDELKLKSDEDE 575
+T+DE ED+
Sbjct: 201 VTLDEFLESCQEDD 214
>gi|7657247 Kv channel interacting protein 1 isoform 2 [Homo
sapiens]
Length = 216
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 506 FEDMDLNKDGEVPPEEFSTFIKAQVSEGKGR----LMPGQDPEKTIGDMFQNQDRNQDGK 561
F D+NKDG + EE +KA + + G+ ++ P + + FQ D+N+DG
Sbjct: 131 FNLYDINKDGYINKEEMMDIVKA-IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGI 189
Query: 562 ITVDELKLKSDEDE 575
+T+DE ED+
Sbjct: 190 VTLDEFLESCQEDD 203
>gi|78190488 Kv channel interacting protein 4 isoform 3 [Homo
sapiens]
Length = 188
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 506 FEDMDLNKDGEVPPEEFSTFIKAQVSEGKGR----LMPGQDPEKTIGDMFQNQDRNQDGK 561
F D+NKDG + EE +KA + + G+ ++ P + + FQ D+N+DG
Sbjct: 103 FNLYDINKDGYITKEEMLDIMKA-IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGV 161
Query: 562 ITVDELKLKSDEDE 575
+T+DE +DE
Sbjct: 162 VTIDEFIESCQKDE 175
>gi|78190486 Kv channel interacting protein 4 isoform 5 [Homo
sapiens]
Length = 225
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 506 FEDMDLNKDGEVPPEEFSTFIKAQVSEGKGR----LMPGQDPEKTIGDMFQNQDRNQDGK 561
F D+NKDG + EE +KA + + G+ ++ P + + FQ D+N+DG
Sbjct: 140 FNLYDINKDGYITKEEMLDIMKA-IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGV 198
Query: 562 ITVDELKLKSDEDE 575
+T+DE +DE
Sbjct: 199 VTIDEFIESCQKDE 212
>gi|22212902 Kv channel interacting protein 4 isoform 4 [Homo
sapiens]
Length = 229
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 506 FEDMDLNKDGEVPPEEFSTFIKAQVSEGKGR----LMPGQDPEKTIGDMFQNQDRNQDGK 561
F D+NKDG + EE +KA + + G+ ++ P + + FQ D+N+DG
Sbjct: 144 FNLYDINKDGYITKEEMLDIMKA-IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGV 202
Query: 562 ITVDELKLKSDEDE 575
+T+DE +DE
Sbjct: 203 VTIDEFIESCQKDE 216
>gi|22212900 Kv channel interacting protein 4 isoform 3 [Homo
sapiens]
Length = 188
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 506 FEDMDLNKDGEVPPEEFSTFIKAQVSEGKGR----LMPGQDPEKTIGDMFQNQDRNQDGK 561
F D+NKDG + EE +KA + + G+ ++ P + + FQ D+N+DG
Sbjct: 103 FNLYDINKDGYITKEEMLDIMKA-IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGV 161
Query: 562 ITVDELKLKSDEDE 575
+T+DE +DE
Sbjct: 162 VTIDEFIESCQKDE 175
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.142 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,393,878
Number of Sequences: 37866
Number of extensions: 1331833
Number of successful extensions: 3079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2806
Number of HSP's gapped (non-prelim): 188
length of query: 582
length of database: 18,247,518
effective HSP length: 108
effective length of query: 474
effective length of database: 14,157,990
effective search space: 6710887260
effective search space used: 6710887260
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.