BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|190610010 hypothetical protein LOC317761 [Homo sapiens] (587 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|190610010 hypothetical protein LOC317761 [Homo sapiens] 1187 0.0 gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens] 50 6e-06 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 48 2e-05 gi|55770834 centromere protein F [Homo sapiens] 46 8e-05 gi|87298937 centrosomal protein 110kDa [Homo sapiens] 46 1e-04 gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] 45 1e-04 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 45 2e-04 gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 44 5e-04 gi|225579095 S-phase cyclin A-associated protein in the ER isofo... 44 5e-04 gi|225579092 S-phase cyclin A-associated protein in the ER isofo... 44 5e-04 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 43 0.001 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 43 0.001 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 42 0.001 gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 42 0.001 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 0.002 gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 42 0.002 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 42 0.002 gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 42 0.002 gi|33946313 ninein isoform 4 [Homo sapiens] 42 0.002 gi|33946321 ninein isoform 5 [Homo sapiens] 42 0.002 gi|148536871 ninein isoform 1 [Homo sapiens] 42 0.002 gi|148536869 ninein isoform 2 [Homo sapiens] 42 0.002 gi|71061468 centromere protein E [Homo sapiens] 41 0.003 gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 41 0.003 gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 41 0.003 gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 40 0.006 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 40 0.006 gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 40 0.006 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 40 0.006 gi|110815815 centlein isoform 1 [Homo sapiens] 40 0.008 >gi|190610010 hypothetical protein LOC317761 [Homo sapiens] Length = 587 Score = 1187 bits (3071), Expect = 0.0 Identities = 587/587 (100%), Positives = 587/587 (100%) Query: 1 MNDSLFVSLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDE 60 MNDSLFVSLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDE Sbjct: 1 MNDSLFVSLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDE 60 Query: 61 EIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKE 120 EIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKE Sbjct: 61 EIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKE 120 Query: 121 VLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTK 180 VLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTK Sbjct: 121 VLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTK 180 Query: 181 WTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETL 240 WTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETL Sbjct: 181 WTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETL 240 Query: 241 EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI 300 EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI Sbjct: 241 EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI 300 Query: 301 KEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQ 360 KEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQ Sbjct: 301 KEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQ 360 Query: 361 SNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAENFPR 420 SNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAENFPR Sbjct: 361 SNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAENFPR 420 Query: 421 TSEIPIFLGTPKAVKAPESLEKIKFPKTPPFEINRNRNAVPEVQTEKESPGLSFLMSYTS 480 TSEIPIFLGTPKAVKAPESLEKIKFPKTPPFEINRNRNAVPEVQTEKESPGLSFLMSYTS Sbjct: 421 TSEIPIFLGTPKAVKAPESLEKIKFPKTPPFEINRNRNAVPEVQTEKESPGLSFLMSYTS 480 Query: 481 RSPGLNLFDSSVFDTEISSDQFNEHYSARNLNPLSSEQEIGNLLEKPEGEDGFTFSFPSD 540 RSPGLNLFDSSVFDTEISSDQFNEHYSARNLNPLSSEQEIGNLLEKPEGEDGFTFSFPSD Sbjct: 481 RSPGLNLFDSSVFDTEISSDQFNEHYSARNLNPLSSEQEIGNLLEKPEGEDGFTFSFPSD 540 Query: 541 TSTHTFGAGKDDFSFPFSFGQGQNSIPSSSLKGFSSSSQNTTQFTFF 587 TSTHTFGAGKDDFSFPFSFGQGQNSIPSSSLKGFSSSSQNTTQFTFF Sbjct: 541 TSTHTFGAGKDDFSFPFSFGQGQNSIPSSSLKGFSSSSQNTTQFTFF 587 >gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens] Length = 1079 Score = 50.1 bits (118), Expect = 6e-06 Identities = 128/597 (21%), Positives = 233/597 (39%), Gaps = 111/597 (18%) Query: 4 SLFVSLDRLLL--EFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINAT--- 58 SL +L+ L + E YE+ I Q + E ++ K T+ H+ A Sbjct: 33 SLLEALEELRMRREAEIHYEEQIGKIIVETQELKWQKETLQNQKETLAEQHKEAMAVFKK 92 Query: 59 ---------DEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKE 109 +EE Y +E + K T + + +Q + + + V+ Sbjct: 93 QLQMKMCALEEEKGKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKVSEMEQKVQLHLL 152 Query: 110 MYHDYICQYKEVLKQYQLKYSETPFSREYYEKKREH--EEIQSR-------------VLA 154 DY Q E+ K Y + +E +EK ++ E IQS + + Sbjct: 153 AKEDYHKQLSEIEKYYATITGQFGLVKENHEKLEQNVREAIQSNKRLSALNKKQEAEICS 212 Query: 155 CTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEV- 213 ++LK + +K +V + + + +N+ + Q++ + + + + ++ +E+ Sbjct: 213 LKKELKKAASDLIKSKVTCQY-KMGEENINLTIKEQKFQELQERLNMELELNEKINEEIT 271 Query: 214 ----DEMEIEINY------LNQQISRHNETKALSETLEEKNKNTENRKEL-KERIFGKDE 262 ++ +I I++ L QQI + E +A + L+E N+ E EL +E++ +E Sbjct: 272 HIQEEKQDIIISFQHMQQLLRQQIQANTEMEAELKVLKENNQTLERDNELQREKVKENEE 331 Query: 263 HVLTLNKTQSSQLFLPYESQKLVRPIKMHSSE--PRVADIKEE-SSAKQSKLANIDFRQK 319 L L E +K + K H+ E + IK E SS K++ + + K Sbjct: 332 KFLNLQN----------EHEKALGTWKRHAEELNGEINKIKNELSSLKETHIKLQEHYNK 381 Query: 320 -------ENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQWSEKGDK 372 E D + N V+N + S ++T S +Q + T Q+ N E Sbjct: 382 LCNQKTFEEDKKFQNVPEVNNEN--SEMSTEKSENTIIQ-KYNTEQEIREENM--ENFCS 436 Query: 373 DAEYGDKGTVRQVRESKCTSQAIY--TEHFGKSIENDSDEVEERAENFPRTSEIPIFLGT 430 D EY +K + +E + I + F KS +N+ D V + EN SEI Sbjct: 437 DTEYREK---EEKKEGSFIEEIIIDDLQLFEKSFKNEIDTVVSQDEN---QSEI------ 484 Query: 431 PKAVKAPESLEKIKFPKTPPFEINRNRNAV-PEVQ-----------TEKESPGLSFLMSY 478 ++ SL+K + + NR +V E++ TE +SP F++ Sbjct: 485 --SLSKTLSLDKEVISQGQTSNVTDNRKSVTTEIKDKICLEKDNGCTEFKSPNNHFVVLD 542 Query: 479 TS---------RSPGLNLFDSSV-FDTEISSDQFNE------HYSARNLNPLSSEQE 519 T+ R+ GL++ + V + E + FN H + N N SE E Sbjct: 543 TAIETEKIHLERTRGLDVHHTDVNLEVENNKTSFNSILNETAHNTYHNNNKDVSENE 599 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 48.1 bits (113), Expect = 2e-05 Identities = 78/414 (18%), Positives = 166/414 (40%), Gaps = 45/414 (10%) Query: 27 KEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWKPTCDVF 86 KEEM + I E+ + T+ + E + ++ + ++K + + + Sbjct: 1087 KEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKS 1146 Query: 87 RKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQ-LKYSETPFSREYYEKKREH 145 K ++Q+Q + E+DK + + K +++Q LK S ++ +K E Sbjct: 1147 LKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEF 1206 Query: 146 EEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHASNLTKS 205 +++ +E+L + I K + A + T +NI + +T IL S+ Sbjct: 1207 KKL-------SEELAIQLDICCK-KTEALLEAKTNELINISS--SKTNAILSRISHCQHR 1256 Query: 206 SSELKK-------EVDEMEIEINYLNQQISRHN-ETKALSETLEEKNKNTENRKELKERI 257 ++++K+ V E+E ++ L ++ + N + + LEEK ++ K E + Sbjct: 1257 TTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESL 1316 Query: 258 FGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSE--PRVADIKEESSAKQSKLANID 315 + E L K +Q E + + +K SE V +KEE K+ +++++ Sbjct: 1317 VTEKE---ALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLS 1373 Query: 316 FRQKENDTQIFNDSAVD-------------NHSKCSHITTITSSQKFMQVRLLTPQKQSN 362 + + + Q+ N ++ + KC + + +V L+ +K S Sbjct: 1374 KQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLS--FKVDTLSKEKISA 1431 Query: 363 SNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAE 416 Q + +K +E+ K +S+ T + +E S E E+ E Sbjct: 1432 LEQVDDWSNKFSEWKKKA------QSRFTQHQNTVKELQIQLELKSKEAYEKDE 1479 Score = 41.2 bits (95), Expect = 0.003 Identities = 76/408 (18%), Positives = 167/408 (40%), Gaps = 38/408 (9%) Query: 21 EQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWK 80 +Q + +E +++R C E I+ +K + A E++D + E+IKD K Sbjct: 285 QQRVKRQENLLKR---CKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEK 341 Query: 81 PTC-----DVFRKHEDYMQDQFTVYQGT---VEKDKEMYHDYICQYKEVLKQYQLKYSET 132 D E QD+ V T + + EM + I Q + +KQ + E Sbjct: 342 TKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEEL 401 Query: 133 PFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWT-LNIVNLRCE 191 +E E + EE++ + T Q +K + ++ K + ++L+ E Sbjct: 402 REQKEKSE-RAAFEELEKAL--STAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 458 Query: 192 TQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRK 251 + + ++ K SSE E ++ L+++ E + L++ L+ + + E ++ Sbjct: 459 LSRVKQEVVDVMKKSSE------EQIAKLQKLHEKELARKE-QELTKKLQTRER--EFQE 509 Query: 252 ELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKL 311 ++K + L +++ + Q L E +L + + SE ++ D+++E+ ++++ Sbjct: 510 QMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 569 Query: 312 ANIDF---------RQKENDTQIFNDSAVDNHSK-----CSHITTITSSQKFMQVRLLTP 357 ++ + + D + ++ + H+K T S K Q L T Sbjct: 570 LELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTE 629 Query: 358 QKQSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIE 405 + Q Q+ + +K E ++ +++ + QA E K++E Sbjct: 630 KLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE 677 Score = 40.0 bits (92), Expect = 0.006 Identities = 69/317 (21%), Positives = 129/317 (40%), Gaps = 60/317 (18%) Query: 8 SLDRLLLEFVFQYEQDIST--KEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHY 65 SL + L + Q + IS KE I + K ++ K C + + + ++D Sbjct: 1371 SLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEK------CELLDQVQDLSFKVDTL 1424 Query: 66 CKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQY 125 K + +W + F + + Q +FT +Q TV KE+ Q Sbjct: 1425 SKEKISALEQVDDWS---NKFSEWKKKAQSRFTQHQNTV--------------KELQIQL 1467 Query: 126 QLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIF--MKFRVPAPFPSLTKWTL 183 +LK S+E YEK + ++ E+L F +K + + K Sbjct: 1468 ELK------SKEAYEKDEQINLLK-------EELDQQNKRFDCLKGEMEDDKSKMEKKES 1514 Query: 184 NI-VNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKAL--SETL 240 N+ L+ +T I+ EL+ + + IEI LN+ + +N+ K + E + Sbjct: 1515 NLETELKSQTARIM-----------ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELV 1563 Query: 241 EEKNKNTENRKELKERIFGKDEHVLTL-NKTQSSQLFLPYESQKLVR---PIKMHSSEPR 296 ++ E +E R+ +E +LTL N+ S + L + ++L +K E + Sbjct: 1564 QKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELK 1623 Query: 297 VAD--IKEESSAKQSKL 311 + ++ ES+AK ++L Sbjct: 1624 ALEDRLESESAAKLAEL 1640 Score = 33.9 bits (76), Expect = 0.43 Identities = 70/383 (18%), Positives = 149/383 (38%), Gaps = 37/383 (9%) Query: 2 NDSLFVSLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEE 61 ++ L +S ++ E + E ++ K + + NK + +E + RI E ++ ++ Sbjct: 520 SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 579 Query: 62 IDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEV 121 + S+++ + K KH + ++ +E K + +V Sbjct: 580 LQENKNQSKDLAVHLEAEK------NKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 633 Query: 122 LKQ-YQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTK 180 LKQ YQ + + RE E+++E ++ +MNE K V Sbjct: 634 LKQQYQTEMEKL---REKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQT------ 684 Query: 181 WTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETL 240 + +L E ++LK L + S LK + D+M+ E+ + H++ + S Sbjct: 685 ---ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIK 741 Query: 241 EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI 300 E + K LK++I ++ L L + + L IK E + A Sbjct: 742 EHEVSIQRTEKALKDQI---NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASA 798 Query: 301 K------------EESSAKQSKLANIDFRQKENDTQ--IFNDSAVDNHSKCSHITTITSS 346 K E++ A + +LA + + + +T+ + + ++ + T + Sbjct: 799 KLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDA 858 Query: 347 QKFMQVRLLTPQKQSNSNQWSEK 369 K +QV+ L Q + +++ +K Sbjct: 859 HK-IQVQDLMQQLEKQNSEMEQK 880 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 46.2 bits (108), Expect = 8e-05 Identities = 97/441 (21%), Positives = 173/441 (39%), Gaps = 57/441 (12%) Query: 13 LLEFVFQYEQDISTKEEMIQRINKCCEDI---KENKVTI-CRIHETINATD----EEIDH 64 L+ QY+Q + + Q++ K ED+ ++N + C + + I + EE+ Sbjct: 343 LVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSR 402 Query: 65 YCKHSEEIKDNCRNWKPTCDVFRKHEDYMQ-------DQFTVYQGTVEKDKEMYHDYICQ 117 + + + C K + M D+ T + +E + E + +C+ Sbjct: 403 QQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCR 462 Query: 118 YKEVLKQYQLKYSETPFSREYYEKK----REHEEIQSRVLACTEQLKMNETIFMKFRVPA 173 ++ + Q+K +E S E +K+ + H E ++R + E N + Sbjct: 463 AEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNF 522 Query: 174 PFPSLTKWTLNIVNLRCETQDILKHASNLTKSS-----SELKKEVD-------EMEIEIN 221 K T LR + I + ++LT ++L+K+ D + E I Sbjct: 523 AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIE 582 Query: 222 YLNQQISR-HNETKALSETLEEKNKNTENRKELKERIF---GKDEHVLTLNKTQSSQL-- 275 LN ++S+ E+KAL LE K K E KE K ++E +LT +++ L Sbjct: 583 QLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQS 642 Query: 276 -FLPYESQKLVRPIKMHSSEPRVADI---KEESSAKQSKLANI-DFRQKENDTQIF---- 326 E+ + IK H RV + +E S + L N+ D + E +TQ Sbjct: 643 KINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYME 702 Query: 327 ----NDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQWSEKG----DKDAEYGD 378 + + H K + +SQ QV L + Q SN+ +K D AEY Sbjct: 703 LQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEY-- 760 Query: 379 KGTVRQVRESKCTSQAIYTEH 399 ++R + +SK S +H Sbjct: 761 -ESLRDLLKSKDASLVTNEDH 780 Score = 39.7 bits (91), Expect = 0.008 Identities = 53/272 (19%), Positives = 115/272 (42%), Gaps = 44/272 (16%) Query: 9 LDRLLLEFVFQYEQ----DISTKEEM---IQRINKCCEDIKENKVTICRIHETINATDEE 61 LD+LL F E+ +I KEE ++ + +++ E +C E + AT++ Sbjct: 2229 LDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2288 Query: 62 IDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEV 121 +D + +++++ + + K + + Q K+ E + D + E Sbjct: 2289 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQL--------KESEHHADLLKGRVEN 2340 Query: 122 LKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKW 181 L++ +L+ + T +EH +++ + E +K ++ SL Sbjct: 2341 LER-ELEIART---------NQEHAALEA-------ENSKGEVETLKAKIEGMTQSLRGL 2383 Query: 182 TLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLE 241 L++V +R E + NLT + ++ + E+EI IN + I + E E ++ Sbjct: 2384 ELDVVTIRSEKE-------NLTNELQKEQERISELEI-INSSFENILQEKE----QEKVQ 2431 Query: 242 EKNKNTENRKELKERIFGKDEHVLTLNKTQSS 273 K K++ + L+ ++ +E V L+ Q + Sbjct: 2432 MKEKSSTAMEMLQTQLKELNERVAALHNDQEA 2463 Score = 33.1 bits (74), Expect = 0.73 Identities = 46/211 (21%), Positives = 81/211 (38%), Gaps = 39/211 (18%) Query: 12 LLLEFVFQYEQDISTKEEMIQRINKCC--------------EDIKENKVTICRIHETINA 57 LLL+ QYE +I T E + +C E++ + +I E + Sbjct: 2713 LLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2772 Query: 58 TDEE----IDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDK----- 108 T + ++ K +E + + +C + ++ +Q + + Q EK K Sbjct: 2773 TKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVM 2832 Query: 109 ----EMYHDYICQYKEVLK-------QYQLKYSETPFSREYYEKKREHEEIQSRVLACTE 157 + I + KE L+ +Y KY S E EK +E E Q L C++ Sbjct: 2833 DTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHL-CSQ 2891 Query: 158 QLKMNE----TIFMKFRVPAPFPSLTKWTLN 184 Q K + + P+P PS+T+ L+ Sbjct: 2892 QSKQDSRGSPLLGPVVPGPSPIPSVTEKRLS 2922 Score = 32.7 bits (73), Expect = 0.95 Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 14/105 (13%) Query: 208 ELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKELKERIFGKDEHVLTL 267 EL+ E+E +I L + + +T E L+ KN EN EL + K V + Sbjct: 2557 ELRNLTVELEQKIQVLQSKNASLQDTL---EVLQSSYKNLENELELTK--MDKMSFVEKV 2611 Query: 268 NKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLA 312 NK + + L E MH + A+++EE S ++++LA Sbjct: 2612 NKMTAKETELQRE---------MHEMAQKTAELQEELSGEKNRLA 2647 Score = 30.8 bits (68), Expect = 3.6 Identities = 41/195 (21%), Positives = 78/195 (40%), Gaps = 18/195 (9%) Query: 187 NLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKN 246 NL+ E Q +++ +L K+ ++ E+ E ++N+ Q+ N K E LE++ K Sbjct: 64 NLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQL---NSGKKQIEKLEQELKR 120 Query: 247 TENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKE---- 302 ++ E ++ + L T P + P + +S + D+KE Sbjct: 121 CKSELERSQQAAQSADVSLNPCNTPQKIFTTP------LTPSQYYSGS-KYEDLKEKYNK 173 Query: 303 ESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQK-QS 361 E ++ A + Q + +Q + +++ H SS F + TP S Sbjct: 174 EVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARH---QASSSVFSWQQEKTPSHLSS 230 Query: 362 NSNQWSEKGDKDAEY 376 NS + + D A Y Sbjct: 231 NSQRTPIRRDFSASY 245 >gi|87298937 centrosomal protein 110kDa [Homo sapiens] Length = 2325 Score = 45.8 bits (107), Expect = 1e-04 Identities = 72/411 (17%), Positives = 153/411 (37%), Gaps = 82/411 (19%) Query: 23 DISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSE-------EIKDN 75 DIS ++ +Q + ++E + + + +N +++ H KH + ++ + Sbjct: 1851 DISAMQQQLQEKREAVNSLQEE---LANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKD 1907 Query: 76 CRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFS 135 W + +K E+ Q Q V Q +E++K +L E F Sbjct: 1908 ISEWANRFEDCQKEEETKQQQLQVLQNEIEENK----------------LKLVQQEMMFQ 1951 Query: 136 REYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDI 195 R E++ E ++++ + EQ Sbjct: 1952 RLQKERESEESKLETSKVTLKEQ------------------------------------- 1974 Query: 196 LKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENR-KELK 254 L K ++ K ++D++ ++ +++ E + E+LE+ T+ + E + Sbjct: 1975 ---QHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSERE 2031 Query: 255 ERIFGKDEHVLTLNKTQSSQL--FLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLA 312 +++ K +L L K S F +Q L K +E +VA +KE ++S+L Sbjct: 2032 QQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKK---AEKQVASLKEALKIQRSQLE 2088 Query: 313 NIDFRQKENDTQIFNDSAV------DNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQW 366 QK+ ++ I + A DNH + + + ++ L +KQ + + Sbjct: 2089 KNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTEL---KKQMANQKD 2145 Query: 367 SEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAEN 417 E+ + + +V++ TS + F + D + + ER EN Sbjct: 2146 LERRQMEISDAMRTLKSEVKDEIRTSLKNLNQ-FLPELPADLEAILERNEN 2195 Score = 40.8 bits (94), Expect = 0.004 Identities = 63/280 (22%), Positives = 115/280 (41%), Gaps = 44/280 (15%) Query: 19 QYEQDISTKEEMIQR----INKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKD 74 + + D++TK E++++ + + C+ E + + I+A E +++Y EI D Sbjct: 323 ELKSDLNTKNELLKQKTIELTRACQKQYELEQELA--FYKIDAKFEPLNYYPSEYAEI-D 379 Query: 75 NCRNWKPTCDVFRKH------EDYMQDQFTVYQ-GTVEKDKEMYHDYICQYKEVLKQYQL 127 + P R E Y+ D Q +E D+++ +D++ QL Sbjct: 380 KAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQL 439 Query: 128 KYSETPFSREYYEKKREHEEIQS---RVLACTEQLK-MNETIFMKFRVPAPFPSLTKWT- 182 + E S H+EI+ ++L TE+ K + E I +K A L K Sbjct: 440 EDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLS 499 Query: 183 --LNIVN-LRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKA---- 235 L +VN LR E D+ + + +KE+ +++I I+ L+ + +H+ KA Sbjct: 500 GRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSG 559 Query: 236 ------------------LSETLEEKNKNTENRKELKERI 257 L E L K TE K+L+E++ Sbjct: 560 KEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQL 599 Score = 39.3 bits (90), Expect = 0.010 Identities = 79/354 (22%), Positives = 145/354 (40%), Gaps = 33/354 (9%) Query: 25 STKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWKPTCD 84 S EE+ + + I E K + I + I +E + + + K +N Sbjct: 1647 SLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQ 1706 Query: 85 VFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEK-KR 143 + ++ Q +EK + + + + + + Q + E + ++ E+ KR Sbjct: 1707 LENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKR 1766 Query: 144 EHEEI--QSRVL-ACTEQL-KMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHA 199 E E + +SR L +C E L K E + K + + TK L + + Sbjct: 1767 EIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQ----- 1821 Query: 200 SNLTKSSSELKKEVDEMEIEINYLNQ-QISRHNETKALSETLEEKNKNTENRKELKERIF 258 SNL K L+ V +++ E++ LN+ ++S HN+ A+ + L+EK E L+E + Sbjct: 1822 SNLEK----LELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKR---EAVNSLQEELA 1874 Query: 259 GKDEHV----LTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLANI 314 +H+ L T Q L E +L + I ++ R D ++E KQ +L + Sbjct: 1875 NVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN--RFEDCQKEEETKQQQLQVL 1932 Query: 315 DFRQKENDTQI------FNDSAVDNHSKCSHITTITSSQKFMQVRL---LTPQK 359 +EN ++ F + S+ S + T + K Q +L LT QK Sbjct: 1933 QNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQK 1986 Score = 38.5 bits (88), Expect = 0.017 Identities = 90/423 (21%), Positives = 159/423 (37%), Gaps = 79/423 (18%) Query: 8 SLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCK 67 + +R LE V + E+D+ K MI+ E++K + EEI + K Sbjct: 263 AFERFSLEEVERLERDLEKK--MIET-----EELKSKQTRFL----------EEIKNQDK 305 Query: 68 HSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDY-----ICQYK--- 119 ++ +K+ K +C+ + D + Q T+E + Y + YK Sbjct: 306 LNKSLKEEAMLQKQSCEELKS--DLNTKNELLKQKTIELTRACQKQYELEQELAFYKIDA 363 Query: 120 --EVLKQYQLKYSE---TPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAP 174 E L Y +Y+E P Y K R R + TE ++ ++ + P Sbjct: 364 KFEPLNYYPSEYAEIDKAPDESPYIGKSR-----YKRNMFATESYIIDSAQAVQIKKMEP 418 Query: 175 FPSLTKWTLNI---VNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHN 231 L +N+ L + +D K S SEL E+++ E QQI R Sbjct: 419 DEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAE-------QQILRAT 471 Query: 232 ET-KALSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKM 290 E K L E ++ K + + L +++ G+ + +NK + L L + +K Sbjct: 472 EEFKQLEEAIQLKKISEAGKDLLYKQLSGR---LQLVNKLRQEALDLELQMEKQ------ 522 Query: 291 HSSEPRVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFM 350 K+E + KQ ++ D QI DS K SH+ S K Sbjct: 523 ----------KQEIAGKQKEI---------KDLQIAIDSLDSKDPKHSHMKA-QKSGKEQ 562 Query: 351 QVRLLTPQKQSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDE 410 Q+ ++ Q Q ++ E + A+ ++ ++ + E Q E K +E Sbjct: 563 QLDIMNKQYQQLESRLDEILSRIAKETEE--IKDLEEQLTEGQIAANEALKKDLEGVISG 620 Query: 411 VEE 413 ++E Sbjct: 621 LQE 623 Score = 34.3 bits (77), Expect = 0.33 Identities = 35/157 (22%), Positives = 72/157 (45%), Gaps = 26/157 (16%) Query: 196 LKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALS-----ETLEEKN------ 244 L+ N K E + + +ME EI+YL + + E + L+ E EEK Sbjct: 894 LEARMNFDKRQHEAR--IQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQL 951 Query: 245 KNTENRKEL-----KERIFGKDEH-------VLTLNKTQSSQLFLPYESQKLVRPIKMHS 292 + E +K+L +E++FG D+ V T +K +++L + + K + M Sbjct: 952 RELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKI 1011 Query: 293 SEPRVADIKE-ESSAKQSKLANIDFRQKENDTQIFND 328 ++ R +++E E ++++ A D + E + ++ + Sbjct: 1012 NQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQN 1048 >gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] Length = 388 Score = 45.4 bits (106), Expect = 1e-04 Identities = 64/284 (22%), Positives = 120/284 (42%), Gaps = 41/284 (14%) Query: 27 KEEMIQRINKCCEDIKENKVTICRIHETINATDEE-----IDHYCKHSEEIKDNCR---- 77 +E++ +RIN +++ K + + E + E I H K E++++ R Sbjct: 31 EEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELMLISHQ-KSIEQLQETLRQKLL 89 Query: 78 ---NWKPTCDVF-----RKHEDYMQDQFTVYQGT----VEKDKEMYHDYICQYKEVLKQY 125 NWK + +H ++Q +++ ++ +KE + D I +YK+ ++ Sbjct: 90 SDDNWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQLDIEKEKHQDVIQKYKKEQEEL 149 Query: 126 QLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNI 185 Q+K S+ +++ V E+L + T R S K N+ Sbjct: 150 QMKISDLITGAT--------RDLRQEVTTLKEKLHKSHT-----RYTEESNSKEKEIENL 196 Query: 186 VNLRCETQDILKHASNLTKSSSE-LKKEVDEMEIEINYL----NQQISRHNETKALSETL 240 NL E + LK + S SE L+KE+++ E+ + Q I + N+++ + L Sbjct: 197 KNLVAEFESRLKKEIDSNDSVSENLRKEMEQKSDELKRVMLAQTQLIEQFNQSQEENTFL 256 Query: 241 EEK-NKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQK 283 +E + E R EL E + E +L L+K + S F P K Sbjct: 257 QETVRRECEERFELTEALSQAREQLLELSKLRGSLPFSPCSLSK 300 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 45.1 bits (105), Expect = 2e-04 Identities = 60/256 (23%), Positives = 115/256 (44%), Gaps = 55/256 (21%) Query: 103 TVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEKK-----REHEEIQSRVLACTE 157 + E +KEM KE ++ + + +++ R+ E+K +E ++Q +V A +E Sbjct: 843 SAETEKEM-----ATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESE 897 Query: 158 QL-----KMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKE 212 L + ++ I KF++ A +T+ + + E + L SELKK+ Sbjct: 898 NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAE---LTAKKRKLEDECSELKKD 954 Query: 213 VDEMEIEINYL-NQQISRHNETKALSETL----EEKNKNTENRKELKER-------IFGK 260 +D++E+ + + ++ + N+ K L+E L E K T +K L+E + + Sbjct: 955 IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAE 1014 Query: 261 DEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLANIDF---- 316 ++ V +LNKT+S E +V D+ ESS +Q K +D Sbjct: 1015 EDKVNSLNKTKS-------------------KLEQQVEDL--ESSLEQEKKLRVDLERNK 1053 Query: 317 RQKENDTQIFNDSAVD 332 R+ E D ++ +S +D Sbjct: 1054 RKLEGDLKLAQESILD 1069 Score = 37.7 bits (86), Expect = 0.030 Identities = 72/393 (18%), Positives = 151/393 (38%), Gaps = 63/393 (16%) Query: 23 DISTKEEMIQRINKC-------CEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDN 75 D+ +E+ + +NK ED++ + ++ + +++ K ++E + Sbjct: 1010 DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 1069 Query: 76 CRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSE---- 131 N K D K +D+ ++ Q VE ++ + Q+++ +K+ Q + E Sbjct: 1070 LENDKQQLDERLKKKDF---EYCQLQSKVEDEQTLG----LQFQKKIKELQARIEELEEE 1122 Query: 132 ---------------TPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFP 176 + ++RE E EE E K E F+K R Sbjct: 1123 IEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEA 1182 Query: 177 SLTKWTLNIVNLRCETQDIL----KHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNE 232 +L + + LR + D + + NL + +L+KE E ++EI+ L+ + ++ Sbjct: 1183 TLQHEAM-VAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSK 1241 Query: 233 TKA----LSETLEE-----KNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQK 283 +KA + TLE+ + KN E ++ L E LT K++ L E+ + Sbjct: 1242 SKANLEKICRTLEDQLSEARGKNEEIQRSLSE---------LTTQKSR-----LQTEAGE 1287 Query: 284 LVRPIKMHSSEPRVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTI 343 L R ++ S +++ +Q++ ++ + + C + Sbjct: 1288 LSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQ 1347 Query: 344 TSSQKFMQVRLLTPQKQSNSN--QWSEKGDKDA 374 ++ + L ++NS QW K + DA Sbjct: 1348 YEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380 >gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] Length = 1684 Score = 43.5 bits (101), Expect = 5e-04 Identities = 70/364 (19%), Positives = 152/364 (41%), Gaps = 49/364 (13%) Query: 13 LLEFVFQYEQDISTKE--EMIQRINKCCEDIKENKVTIC--------RIHETINATDEEI 62 L E + +D K+ ++Q + + I E K + + + I EE Sbjct: 763 LKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEES 822 Query: 63 DHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVL 122 C EE+K R+++ + RK + +Q + Q + + K + + +L Sbjct: 823 VVQC---EELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLL 879 Query: 123 KQYQLKYSETPFSREYYEKK-----REHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPS 177 Q + + S+T E + +K +EHE ++ + + + E I +K + A PS Sbjct: 880 IQVE-EVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSL-AKSPS 937 Query: 178 LTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQI-SRHNETKAL 236 + L+ V +++ + NL K E +++++++++ +++ S ET+ + Sbjct: 938 VKNDPLSSV------KELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTV 991 Query: 237 SETLEE-KNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEP 295 E LE +++ + +++ I G + + L L YE Q ++ Sbjct: 992 KEELESLRSEKDQLSASMRDLIQGAESY---------KNLLLEYEKQSEQLDVE------ 1036 Query: 296 RVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLL 355 KE ++ + ++ ++ RQ N T DN + I T+ S+ K ++V++L Sbjct: 1037 -----KERANNFEHRIEDLT-RQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQIL 1090 Query: 356 TPQK 359 Q+ Sbjct: 1091 EVQR 1094 Score = 33.9 bits (76), Expect = 0.43 Identities = 29/109 (26%), Positives = 57/109 (52%), Gaps = 8/109 (7%) Query: 208 ELKKEVDEMEIEINYLNQQISRHNE-TKALSETLEEKNKNTENRKEL--KERIFGKDEHV 264 EL K+V++ I Y ++ + NE T L ETL+EK++N + ++L + ++ +D+ V Sbjct: 626 ELGKKVEQT---IQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEV 682 Query: 265 LT--LNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKL 311 L+ + L E ++L R +++ S+ +KE + + KL Sbjct: 683 LSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL 731 >gi|225579095 S-phase cyclin A-associated protein in the ER isoform b [Homo sapiens] Length = 1154 Score = 43.5 bits (101), Expect = 5e-04 Identities = 49/204 (24%), Positives = 85/204 (41%), Gaps = 19/204 (9%) Query: 128 KYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVN 187 K S R E K++HEE Q + E+L+ +T+ ++ ++ + KW +++ Sbjct: 284 KLSSPSRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQ-KLLEREKDVRKWKEELLD 342 Query: 188 LRCET-QDILKHAS--------NLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSE 238 R ++ L HA + K + E + +V+E+ IN L Q RH+ L E Sbjct: 343 QRRRMMEEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAF-INTLEAQNKRHDVLSKLKE 401 Query: 239 TLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPI--KMHSSEPR 296 + N+ E R+ +E +DE V Q + L E Q V + K E R Sbjct: 402 YEQRLNELQEERQRRQEEKQARDEAV------QERKRALEAERQARVEELLMKRKEQEAR 455 Query: 297 VADIKEESSAKQSKLANIDFRQKE 320 + ++E + A R +E Sbjct: 456 IEQQRQEKEKAREDAARERARDRE 479 Score = 32.3 bits (72), Expect = 1.2 Identities = 49/206 (23%), Positives = 93/206 (45%), Gaps = 26/206 (12%) Query: 119 KEVLKQYQLKYSET--PFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFP 176 +E+ K+ QLK+ E+ + ++K + E+ S A T+ P P Sbjct: 494 EELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTDY------------APKLTP 541 Query: 177 SLTKWTLNIVNLRCETQDIL-------KHASNLTKSSSELKKEVDEMEIEINYLNQQI-S 228 K ++ N+ ++ L KH + +++S +E+ + E+E L + I Sbjct: 542 YERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLSLKKYIID 601 Query: 229 RHNETKALSETL---EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLV 285 E+ A +E L EE+ KN + K++K R+ + + +L +T++S PY++ KL Sbjct: 602 IVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSPYKA-KLQ 660 Query: 286 RPIKMHSSEPRVADIKEESSAKQSKL 311 R K + +V D ++ K S L Sbjct: 661 RLAKDLLKQVQVQDSGSWANNKVSAL 686 >gi|225579092 S-phase cyclin A-associated protein in the ER isoform a [Homo sapiens] Length = 1400 Score = 43.5 bits (101), Expect = 5e-04 Identities = 49/204 (24%), Positives = 85/204 (41%), Gaps = 19/204 (9%) Query: 128 KYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVN 187 K S R E K++HEE Q + E+L+ +T+ ++ ++ + KW +++ Sbjct: 530 KLSSPSRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQ-KLLEREKDVRKWKEELLD 588 Query: 188 LRCET-QDILKHAS--------NLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSE 238 R ++ L HA + K + E + +V+E+ IN L Q RH+ L E Sbjct: 589 QRRRMMEEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAF-INTLEAQNKRHDVLSKLKE 647 Query: 239 TLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPI--KMHSSEPR 296 + N+ E R+ +E +DE V Q + L E Q V + K E R Sbjct: 648 YEQRLNELQEERQRRQEEKQARDEAV------QERKRALEAERQARVEELLMKRKEQEAR 701 Query: 297 VADIKEESSAKQSKLANIDFRQKE 320 + ++E + A R +E Sbjct: 702 IEQQRQEKEKAREDAARERARDRE 725 Score = 32.3 bits (72), Expect = 1.2 Identities = 49/206 (23%), Positives = 93/206 (45%), Gaps = 26/206 (12%) Query: 119 KEVLKQYQLKYSET--PFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFP 176 +E+ K+ QLK+ E+ + ++K + E+ S A T+ P P Sbjct: 740 EELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTDY------------APKLTP 787 Query: 177 SLTKWTLNIVNLRCETQDIL-------KHASNLTKSSSELKKEVDEMEIEINYLNQQI-S 228 K ++ N+ ++ L KH + +++S +E+ + E+E L + I Sbjct: 788 YERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLSLKKYIID 847 Query: 229 RHNETKALSETL---EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLV 285 E+ A +E L EE+ KN + K++K R+ + + +L +T++S PY++ KL Sbjct: 848 IVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSPYKA-KLQ 906 Query: 286 RPIKMHSSEPRVADIKEESSAKQSKL 311 R K + +V D ++ K S L Sbjct: 907 RLAKDLLKQVQVQDSGSWANNKVSAL 932 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 42.7 bits (99), Expect = 0.001 Identities = 51/256 (19%), Positives = 100/256 (39%), Gaps = 24/256 (9%) Query: 10 DRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHS 69 +++L E + + +S E ++I K E KE E + E+ H K + Sbjct: 589 NKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG-------ERAEELENELHHLEKEN 641 Query: 70 EEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQ-LK 128 E ++ N K TC+ E + +E++ + +K + Q + L+ Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSE--------LERENRKLKKTLDSFKNLTFQLESLE 693 Query: 129 YSETPFSREYYEKKREHEEIQSRVLACTE-QLKMNETIFMKFRVP-------APFPSLTK 180 + E E +R E ++ + + QL+ E K ++ A F + Sbjct: 694 KENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTER 753 Query: 181 WTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETL 240 ++ L E Q + K N K +L+ E+ ++E+E L + + + E L Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813 Query: 241 EEKNKNTENRKELKER 256 E++NK+ E E+ Sbjct: 814 EKENKSLEQETSQLEK 829 Score = 40.4 bits (93), Expect = 0.005 Identities = 53/308 (17%), Positives = 125/308 (40%), Gaps = 19/308 (6%) Query: 21 EQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDE-EIDHYCKHSEEIKDNCRNW 79 E +I +++ +Q +D+ + K + + ET+ E +I + +E + + Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL 570 Query: 80 KPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYY 139 + + E ++D +EK+ ++ H+ I + L + + + + E+Y Sbjct: 571 RQRSQI--SAEARVKD--------IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620 Query: 140 EKKREH-EEIQSRVLACTEQLKMNETIFMKFRVPA-PFPSLTKWTLNIVNLRCETQDILK 197 ++K E EE+++ + ++ ++ + ++ +L + + + + L Sbjct: 621 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 680 Query: 198 HASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKE-LKER 256 NLT L+KE +++ E L + + L+ +NK E+ KE LK+ Sbjct: 681 SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 740 Query: 257 IFGKDEHVLTLNKTQSSQLFLPYESQKLVRPI-----KMHSSEPRVADIKEESSAKQSKL 311 + + + S L E+Q+L + + K+ E + D++ E+ Q L Sbjct: 741 LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNL 800 Query: 312 ANIDFRQK 319 + K Sbjct: 801 EELKISSK 808 Score = 33.1 bits (74), Expect = 0.73 Identities = 48/285 (16%), Positives = 119/285 (41%), Gaps = 41/285 (14%) Query: 21 EQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWK 80 E+ I+ E ++ + +++ T+ + +E + +E + + S I W+ Sbjct: 973 EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE-ERMVQSSPPISGEDNKWE 1031 Query: 81 PTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYE 140 R+ ++ ++ V +E ++ + + K+ LK QLK ET Sbjct: 1032 ------RESQETTRELLKVKDRLIEVERN--NATLQAEKQALKT-QLKQLET-------- 1074 Query: 141 KKREHEEIQSRVLACTEQL----KMNETI-FMKFRVPAPFPSLTKWTLNIVN-------- 187 ++ +Q+++LA Q + N T+ ++ +L + +++N Sbjct: 1075 ---QNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1131 Query: 188 ---LRCETQDILKHASNLTKSSSELKKEVDEMEI----EINYLNQQISRHNETKALSETL 240 L E + ++K +L L K+ +++E+ + + IS+H K+ + L Sbjct: 1132 QSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNL 1191 Query: 241 EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLV 285 E ++++ E+R + G+ E + + K + ++ L ++ + V Sbjct: 1192 EVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETV 1236 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 42.7 bits (99), Expect = 0.001 Identities = 51/256 (19%), Positives = 100/256 (39%), Gaps = 24/256 (9%) Query: 10 DRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHS 69 +++L E + + +S E ++I K E KE E + E+ H K + Sbjct: 589 NKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG-------ERAEELENELHHLEKEN 641 Query: 70 EEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQ-LK 128 E ++ N K TC+ E + +E++ + +K + Q + L+ Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSE--------LERENRKLKKTLDSFKNLTFQLESLE 693 Query: 129 YSETPFSREYYEKKREHEEIQSRVLACTE-QLKMNETIFMKFRVP-------APFPSLTK 180 + E E +R E ++ + + QL+ E K ++ A F + Sbjct: 694 KENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTER 753 Query: 181 WTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETL 240 ++ L E Q + K N K +L+ E+ ++E+E L + + + E L Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813 Query: 241 EEKNKNTENRKELKER 256 E++NK+ E E+ Sbjct: 814 EKENKSLEQETSQLEK 829 Score = 40.4 bits (93), Expect = 0.005 Identities = 53/308 (17%), Positives = 125/308 (40%), Gaps = 19/308 (6%) Query: 21 EQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDE-EIDHYCKHSEEIKDNCRNW 79 E +I +++ +Q +D+ + K + + ET+ E +I + +E + + Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL 570 Query: 80 KPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYY 139 + + E ++D +EK+ ++ H+ I + L + + + + E+Y Sbjct: 571 RQRSQI--SAEARVKD--------IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620 Query: 140 EKKREH-EEIQSRVLACTEQLKMNETIFMKFRVPA-PFPSLTKWTLNIVNLRCETQDILK 197 ++K E EE+++ + ++ ++ + ++ +L + + + + L Sbjct: 621 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 680 Query: 198 HASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKE-LKER 256 NLT L+KE +++ E L + + L+ +NK E+ KE LK+ Sbjct: 681 SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 740 Query: 257 IFGKDEHVLTLNKTQSSQLFLPYESQKLVRPI-----KMHSSEPRVADIKEESSAKQSKL 311 + + + S L E+Q+L + + K+ E + D++ E+ Q L Sbjct: 741 LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNL 800 Query: 312 ANIDFRQK 319 + K Sbjct: 801 EELKISSK 808 Score = 33.1 bits (74), Expect = 0.73 Identities = 48/285 (16%), Positives = 119/285 (41%), Gaps = 41/285 (14%) Query: 21 EQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWK 80 E+ I+ E ++ + +++ T+ + +E + +E + + S I W+ Sbjct: 972 EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE-ERMVQSSPPISGEDNKWE 1030 Query: 81 PTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYE 140 R+ ++ ++ V +E ++ + + K+ LK QLK ET Sbjct: 1031 ------RESQETTRELLKVKDRLIEVERN--NATLQAEKQALKT-QLKQLET-------- 1073 Query: 141 KKREHEEIQSRVLACTEQL----KMNETI-FMKFRVPAPFPSLTKWTLNIVN-------- 187 ++ +Q+++LA Q + N T+ ++ +L + +++N Sbjct: 1074 ---QNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1130 Query: 188 ---LRCETQDILKHASNLTKSSSELKKEVDEMEI----EINYLNQQISRHNETKALSETL 240 L E + ++K +L L K+ +++E+ + + IS+H K+ + L Sbjct: 1131 QSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNL 1190 Query: 241 EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLV 285 E ++++ E+R + G+ E + + K + ++ L ++ + V Sbjct: 1191 EVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETV 1235 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 42.4 bits (98), Expect = 0.001 Identities = 53/281 (18%), Positives = 132/281 (46%), Gaps = 20/281 (7%) Query: 55 INATDEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDY 114 ++ T E+ D + E ++ N + C+ K + ++ + VE+++E+ + Sbjct: 890 VSLTQEKNDLILQLQAE-QETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSEL 948 Query: 115 ICQYKEVLKQ-YQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLK-MNETIFMKFRVP 172 + +++ + ++LK + ++E + +V TE+++ +NE I R Sbjct: 949 TARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAA 1008 Query: 173 APFPSLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQ-QISRHN 231 + TL+ +++ E S+L+K++ +L+++VDE+E + + +++ Sbjct: 1009 KVVQEAHQQTLDDLHMEEEK------LSSLSKANLKLEQQVDELEGALEQERKARMNCER 1062 Query: 232 ETKALSETLEEKNKNTEN----RKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRP 287 E L L+ ++ EN ++ L E + K+ + +N ++ L + QK V+ Sbjct: 1063 ELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKE 1122 Query: 288 IKMHSSEPRVADIKEESSAKQSKLANIDFRQKENDTQIFND 328 + + ++ D+KE+ A+++ A ++ R++ + TQ D Sbjct: 1123 L-----QTQIKDLKEKLEAERTTRAKME-RERADLTQDLAD 1157 Score = 37.4 bits (85), Expect = 0.039 Identities = 63/352 (17%), Positives = 139/352 (39%), Gaps = 43/352 (12%) Query: 142 KREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHASN 201 K++HEE Q+ + A ++++ T +K + + + + LR E +++ + SN Sbjct: 1469 KQKHEESQALLDASQKEVQALSTELLKLK-----NTYEESIVGQETLRRENKNLQEEISN 1523 Query: 202 LTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKN---------TENRKE 252 LT E K + EME + ++ + T +E E+N++ E + E Sbjct: 1524 LTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAE 1583 Query: 253 LKERIFGKDEHVLTLNKTQ-----SSQLFLPYESQKLVRPIK--------MHSSEPRVAD 299 L+ ++ KDE + + Q S Q L E++ + + ++ E +++ Sbjct: 1584 LERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSC 1643 Query: 300 IKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQK 359 + S L + + K+ Q+ +DS N + +Q L + Sbjct: 1644 ANRQVSEATKSLGQLQIQIKDLQMQL-DDSTQLNSDLKEQVAVAERRNSLLQSEL---ED 1699 Query: 360 QSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFG-----KSIENDSDEVEER 414 + + +E+G + +E ++ E+ YT++ K +E D +++ Sbjct: 1700 LRSLQEQTERGRRLSE-------EELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752 Query: 415 AENFPRTSEIPIFLGTPKAVKAPESLEKIKFPKTPPFEINRNRNAVPEVQTE 466 AE + + A++A E++K + + R R + + T+ Sbjct: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITD 1804 >gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] Length = 1219 Score = 42.4 bits (98), Expect = 0.001 Identities = 93/450 (20%), Positives = 184/450 (40%), Gaps = 56/450 (12%) Query: 31 IQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHE 90 IQRI I+EN+ I E N +E+ D K SE I+ N R + + + K Sbjct: 567 IQRI------IQENERLKQEILEKSNRIEEQND---KISELIERNQRYVEQSNLMMEKRN 617 Query: 91 DYMQDQFTVYQGTV---EKDKEMYHDYICQYKEVLKQYQLKYS-----ETPFSREYYEKK 142 + +Q Q V E++K + + + QLK + ET + E Sbjct: 618 NSLQTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESL 677 Query: 143 REHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPS----LTKWTLNIVNLRCETQDILKH 198 +E + ++ ++ Q K++E + + F S + L + +L E D+ Sbjct: 678 KETDLLRGQLTKV--QAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVE 735 Query: 199 ASNLTKSSSELKK----EVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTEN----- 249 +L K+ SE KK E + E EI+ + + S E L + L++ +T+ Sbjct: 736 KESLEKNLSERKKKSAQERSQAEEEIDEIRK--SYQEELDKLRQLLKKTRVSTDQAAAEQ 793 Query: 250 ----RKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESS 305 + EL+ + K EH+L K + Q + +Q+ + + ++ ++E+ Sbjct: 794 LSLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQR-------DAYQQKLVQLQEKCL 846 Query: 306 AKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQ 365 A Q+++ + K+N+ I N S+ S + S +++ QS + Sbjct: 847 ALQAQITALT---KQNEQHI--KELEKNKSQMSGVEAAASDPSEKVKKIMNQVFQSLRRE 901 Query: 366 WSEKGDKDAEYGDKGTVRQVRES-KCTSQAIYTEHFGKSIENDSDEVEERAENFP-RTSE 423 + + + Y + + + + K + + + + E+ S+E EE+AE P R S+ Sbjct: 902 F----ELEESYNGRTILGTIMNTIKMVTLQLLNQQEQEKEESSSEEEEEKAEERPRRPSQ 957 Query: 424 IPIFLGTPKAVKAPESLEKIKFPKTPPFEI 453 + +AP + E+ + P P ++ Sbjct: 958 EQSASASSGQPQAPLNRERPESPMVPSEQV 987 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 42.0 bits (97), Expect = 0.002 Identities = 54/279 (19%), Positives = 110/279 (39%), Gaps = 49/279 (17%) Query: 21 EQDISTKEEMIQRINKCCEDIKENK------------------VTICRIHETINATDEEI 62 EQD + KE+ +Q K +DI++ K CR + I +EE+ Sbjct: 1088 EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL 1147 Query: 63 DHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVL 122 H E N K + + + +Q + + VE++K + +++L Sbjct: 1148 K---SHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEK--------RNQQIL 1196 Query: 123 KQYQLKYSETPFSREYYEKKRE-HEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKW 181 K Q+K E +E+ EK+ + H EI+ + + + + + M+ +T Sbjct: 1197 KD-QVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQ---------ITAL 1246 Query: 182 TLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEIN--------YLNQQISRHNET 233 N+ ++ E Q + S L K + +L+ E+ +E + L + + E Sbjct: 1247 NENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEI 1306 Query: 234 KALSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQS 272 + L + E + +N + + G++ L + TQ+ Sbjct: 1307 EKLQTKVLELQRKLDNTTAAVQEL-GRENQSLQIKHTQA 1344 Score = 30.4 bits (67), Expect = 4.7 Identities = 47/271 (17%), Positives = 103/271 (38%), Gaps = 36/271 (13%) Query: 119 KEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSL 178 KE L + + KY + +++RE +E L ++ + + ++ L Sbjct: 378 KEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL 437 Query: 179 TKWT-LNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALS 237 + L+ L + Q + L++ +LK++V + L++ +H E +AL Sbjct: 438 KEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQ 497 Query: 238 ETLEEKNKNTENRKELKERIFG-KDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPR 296 ++ K + +N E R G KD+ + L + S+ Sbjct: 498 QSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEAL-------------------LQKSKEN 538 Query: 297 VADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLT 356 ++ +++E +K+ + E +T + N NH+ +T +T K Sbjct: 539 ISLLEKEREDLYAKI-----QAGEGETAVLNQLQEKNHTLQEQVTQLTEKLK-------- 585 Query: 357 PQKQSNSNQWSEKGDKDAEYGDKGTVRQVRE 387 QS S++ +++ D K +R ++ Sbjct: 586 --NQSESHKQAQENLHDQVQEQKAHLRAAQD 614 Score = 29.6 bits (65), Expect = 8.1 Identities = 30/139 (21%), Positives = 64/139 (46%), Gaps = 20/139 (14%) Query: 184 NIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHN--------ETKA 235 ++ LR E QD+ S ELKKE+++ + L QQ ++ + E ++ Sbjct: 84 DVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQ----GLQQQEAKPDGLVTDSSAELQS 139 Query: 236 LSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEP 295 L + LEE N K++K+ K + T+ + + Y+ ++ +R ++E Sbjct: 140 LEQQLEEAQTENFNIKQMKDLFEQKAAQL----ATEIADIKSKYDEERSLR----EAAEQ 191 Query: 296 RVADIKEESSAKQSKLANI 314 +V + EE + + + + ++ Sbjct: 192 KVTRLTEELNKEATVIQDL 210 >gi|64085252 hypothetical protein LOC145508 [Homo sapiens] Length = 1094 Score = 42.0 bits (97), Expect = 0.002 Identities = 110/559 (19%), Positives = 209/559 (37%), Gaps = 103/559 (18%) Query: 23 DISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCR---NW 79 + S ++ + +C E + K + E + E+++ K ++ D + N Sbjct: 373 NFSAMASELEEVKRCMERKDKEKAHLASQVENLT---RELENGEKQQLQMLDRLKEIQNH 429 Query: 80 KPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYY 139 TC+ RKH D + T + K E Y + Q E LK E Sbjct: 430 FDTCEAERKHADLQISELTRHAEDATKQAERYLSEL-QQSEALK-------------EEA 475 Query: 140 EKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHA 199 EK+RE +++++ S+ +W L L + + Sbjct: 476 EKRREDLKLKAQ------------------------ESIRQWKLKHKKLERALEKQSETV 511 Query: 200 SNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTE--NRKELKERI 257 LT ++++ KE DE++ ++ QQI N K L++ L ++ E + KE K R Sbjct: 512 DELTGKNNQILKEKDELKTQLYAALQQI--ENLRKELNDVLTKRALQEEELHSKEEKLRD 569 Query: 258 FGKDEHVLTLNKTQSSQLFLPYESQ-----KLVRPIKMHSS--EPRVADIKEESSAKQSK 310 + L L S ES+ K+ +K+ + E +A++K+ + ++K Sbjct: 570 IKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAK 629 Query: 311 LANIDFRQKEND---TQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQWS 367 L + K+ + N A + +K + + ++ LT Q +S + + Sbjct: 630 LLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSD---------LTAQAKSRDEETA 680 Query: 368 E-----KGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAENFPR-T 421 K ++D R++++ + Q++ T+H ++E ++F + Sbjct: 681 TIITQLKLERDVHQ------RELKDLTSSLQSVKTKH--------EQNIQELMKHFKKEK 726 Query: 422 SEIPIFLGTPKAVKAPESLEKIKFPKTPPFEINRNR---NAVPEVQTEKESPGLSFLMSY 478 SE + T KA ESLE+ K ++ + + + + E T+ E+ + Y Sbjct: 727 SEAENHIRTLKA----ESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKY 782 Query: 479 TSRSPGLNLFDSSVFDTEISSDQFNEHYSAR-----NLNPLSSEQE-IGNLLEKPEGEDG 532 L + + I + AR L L +EQE I ++ K Sbjct: 783 QCLKDQLEEREKHI---SIEEEHLRRMEEARLQLKDQLLCLETEQESILGVIGKEIDAAC 839 Query: 533 FTFSFPSDTSTHTFGAGKD 551 TFS S F +G D Sbjct: 840 KTFSKDSVEKLKVFSSGPD 858 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 41.6 bits (96), Expect = 0.002 Identities = 69/311 (22%), Positives = 138/311 (44%), Gaps = 42/311 (13%) Query: 75 NCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPF 134 N ++W P ++F K + ++ + E +KEM KE ++ + + + + Sbjct: 827 NVKHW-PWMNLFFKIKPLLK--------SAEAEKEM-----ATMKEDFERTKEELARSEA 872 Query: 135 SREYYEKK-----REHEEIQSRVLACTEQLKMNET-----IFMKFRVPAPFPSLTKWTLN 184 R+ E+K +E ++Q +V + TE L E I K + A LT+ Sbjct: 873 RRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEE 932 Query: 185 IVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYL-NQQISRHNETKALSETLEEK 243 + E ++ NL S LK+++D++E+ + + ++ + N+ K LSE + Sbjct: 933 EEEMNSE---LVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTAL 989 Query: 244 NKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEE 303 +N K KE+ ++ H TL+ Q E K+ IK+++ + D E Sbjct: 990 EENIS--KLTKEKKSLQEAHQQTLDDLQ-------VEEDKVNGLIKINAKLEQQTDDLEG 1040 Query: 304 SSAKQSKL-ANID--FRQKENDTQIFNDSAVDNHSKCSHITTITSSQKF--MQVRLLTPQ 358 S ++ KL A+++ R+ E D ++ +S +D + I ++F Q++ Sbjct: 1041 SLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDD 1100 Query: 359 KQSNSNQWSEK 369 +Q +S Q+ +K Sbjct: 1101 EQVHSLQFQKK 1111 Score = 40.0 bits (92), Expect = 0.006 Identities = 67/319 (21%), Positives = 125/319 (39%), Gaps = 51/319 (15%) Query: 90 EDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSE------------TPFSRE 137 E + +F + Q + D E H Q+++ +K+ Q + E ++ Sbjct: 1082 EKLKKKEFELSQLQAKIDDEQVHSL--QFQKKIKELQARIEELEEEIEAEHTLRAKIEKQ 1139 Query: 138 YYEKKREHEEIQSRVL----ACTEQLKMN---ETIFMKFRVPAPFPSL----TKWTL--- 183 + RE EEI R+ A + Q++MN E F K R +L T TL Sbjct: 1140 RSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199 Query: 184 ---NIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETL 240 ++ L + ++ + L K SELK E+D+M I L++ S T T+ Sbjct: 1200 QADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERT---CRTV 1256 Query: 241 EEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI 300 E++ + + E + ++ H L + K + ++Q ++ E ++ + Sbjct: 1257 EDQFSEIKAKDEQQTQLI----HDLNMQKAR-------LQTQNGELSHRVEEKESLISQL 1305 Query: 301 KEESSAKQSKLANIDFRQKENDTQIFNDSA---VDNHSKCSHITTITSSQKFMQVRLLTP 357 + A +L + RQ E +T+ N A + C + ++ + L Sbjct: 1306 TKSKQALTQQLEELK-RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRA 1364 Query: 358 QKQSNSN--QWSEKGDKDA 374 ++NS QW K + DA Sbjct: 1365 LSKANSEVAQWRTKYETDA 1383 >gi|14165274 golgi-associated microtubule-binding protein HOOK3 [Homo sapiens] Length = 718 Score = 41.6 bits (96), Expect = 0.002 Identities = 103/511 (20%), Positives = 200/511 (39%), Gaps = 89/511 (17%) Query: 2 NDSLFVSLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDI-----------KENKVTICR 50 ND+ +V LDR L + + + +S KEE+ QR ++ + EN+V + R Sbjct: 168 NDA-YVDLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMER 226 Query: 51 IHETINATD----------------EEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQ 94 ++++ + D E++ E KD +++ C+ K ++ Sbjct: 227 LNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKD---DYRIRCEELEKEISELR 283 Query: 95 DQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEKKRE---HEEIQSR 151 Q T+ + + D I +VL+ K S+ E Y+KK E Q + Sbjct: 284 QQNDELT-TLADEAQSLKDEI----DVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVK 338 Query: 152 VLACTEQLKMNETIFMK---FRVPAPFPSLTKWTLNIVNLRCETQDILKHASNLTKSSSE 208 +L + M T+ ++ + A L + +V L+ + K A L Sbjct: 339 LLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKR 398 Query: 209 LKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKELKERIFGKDEHVLTLN 268 LK++VD ++ E + L E +L ET+EE +L + ++ L Sbjct: 399 LKEKVDSLQKEKDRL------RTERDSLKETIEELRCVQAQEGQL------TTQGLMPLG 446 Query: 269 KTQSS-----QLFLPYESQKLVR---PIKMHSSEPRVADIKEESSAKQSKLANIDFRQKE 320 +SS ++ P +KL+R KM +D E+ + QS L + + R+ E Sbjct: 447 SQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSD-NEKIALLQSLLDDANLRKNE 505 Query: 321 NDTQ--IFNDSAVDNHSKCSHITTITSSQ--KFMQVRLLTPQKQSNSNQWSEKGDKDAEY 376 +T+ + N ++ S+ + Q K LL + + + + E + E Sbjct: 506 LETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANN---EL 562 Query: 377 GDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAENFPRTSEIPIFLGTPKAVKA 436 K + + E + + ++ E +++ +E+++ E + + E KA Sbjct: 563 QKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLE--------KAKSV 614 Query: 437 PESLEKIKFPKTPPFEINRNRNAVPEVQTEK 467 +L+ PK +N+ A PE+Q K Sbjct: 615 IRTLD----PK-------QNQGAAPEIQALK 634 >gi|33946313 ninein isoform 4 [Homo sapiens] Length = 2096 Score = 41.6 bits (96), Expect = 0.002 Identities = 61/308 (19%), Positives = 127/308 (41%), Gaps = 55/308 (17%) Query: 59 DEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDY--------MQDQFTVYQGTVEKDKEM 110 ++++ HY K +E +C+ + ++E + ++++ QG KE Sbjct: 636 EDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEA 695 Query: 111 YHDYICQYKEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLAC-----TEQLKMNETI 165 +H+ C+++E KQ Q+K E + + + E+++R+ E+ + + Sbjct: 696 HHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSA 755 Query: 166 FMKFRVPAPFPSLTKW-----TLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEI 220 + + +V L ++ T + E +++ K L K EL++ ++ME E Sbjct: 756 WTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKEL--LEKHQRELQEGREKMETEC 813 Query: 221 NYLNQQISR--HNETKALSETLEEKNKNTENR-----KELKER--------IFGKDEHVL 265 N QI ++ + ++E E ++ E R K+L+E+ F KDE Sbjct: 814 NRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQ 873 Query: 266 -----------TLNKTQSSQLFLPYESQKLVRPIKMHSSEPRV---------ADIKEESS 305 TL + +++ L L E + L + K H + V D++ S Sbjct: 874 ECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSE 933 Query: 306 AKQSKLAN 313 +QS L++ Sbjct: 934 TQQSLLSD 941 Score = 36.6 bits (83), Expect = 0.066 Identities = 66/320 (20%), Positives = 118/320 (36%), Gaps = 68/320 (21%) Query: 67 KHSEEIKDNCRNWKPTCDVFRKHEDYMQDQF----TVYQGTVEKDKEMYHDYICQYKEVL 122 K E I + +K + + D +Q++ T Y +E +KE+ + E+ Sbjct: 1242 KMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELK 1301 Query: 123 KQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQL-KMNETIFMKFRVPAPFPSLTKW 181 K ++ + + Y E K E+EE+ VL ++ K+ E++ + SL Sbjct: 1302 KMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENL 1361 Query: 182 TL----NIVNLRCETQDILKHASNLTKSSSELKKEVDEME-----------IEINYLNQQ 226 + NI+ L ++ + ++ E K+E +E EI +L+ Sbjct: 1362 EIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAHEIAWLHGT 1421 Query: 227 ISRHNE--------------------------TKALSETLEEKNKNTENRKELKERI--- 257 I H E ++E EK K E ++LKER+ Sbjct: 1422 IQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTIL 1481 Query: 258 --------FGKDEHVL---------TLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI 300 G+ E L T ++ Q L YES+KL + + +E + + Sbjct: 1482 VKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNE--ITTL 1539 Query: 301 KEESSAKQSKLANIDFRQKE 320 EE S KL ++ Q+E Sbjct: 1540 NEEDSISNLKLGTLNGSQEE 1559 >gi|33946321 ninein isoform 5 [Homo sapiens] Length = 2090 Score = 41.6 bits (96), Expect = 0.002 Identities = 61/308 (19%), Positives = 127/308 (41%), Gaps = 55/308 (17%) Query: 59 DEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDY--------MQDQFTVYQGTVEKDKEM 110 ++++ HY K +E +C+ + ++E + ++++ QG KE Sbjct: 630 EDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEA 689 Query: 111 YHDYICQYKEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLAC-----TEQLKMNETI 165 +H+ C+++E KQ Q+K E + + + E+++R+ E+ + + Sbjct: 690 HHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSA 749 Query: 166 FMKFRVPAPFPSLTKW-----TLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEI 220 + + +V L ++ T + E +++ K L K EL++ ++ME E Sbjct: 750 WTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKEL--LEKHQRELQEGREKMETEC 807 Query: 221 NYLNQQISR--HNETKALSETLEEKNKNTENR-----KELKER--------IFGKDEHVL 265 N QI ++ + ++E E ++ E R K+L+E+ F KDE Sbjct: 808 NRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQ 867 Query: 266 -----------TLNKTQSSQLFLPYESQKLVRPIKMHSSEPRV---------ADIKEESS 305 TL + +++ L L E + L + K H + V D++ S Sbjct: 868 ECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSE 927 Query: 306 AKQSKLAN 313 +QS L++ Sbjct: 928 TQQSLLSD 935 Score = 36.6 bits (83), Expect = 0.066 Identities = 66/320 (20%), Positives = 118/320 (36%), Gaps = 68/320 (21%) Query: 67 KHSEEIKDNCRNWKPTCDVFRKHEDYMQDQF----TVYQGTVEKDKEMYHDYICQYKEVL 122 K E I + +K + + D +Q++ T Y +E +KE+ + E+ Sbjct: 1236 KMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELK 1295 Query: 123 KQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQL-KMNETIFMKFRVPAPFPSLTKW 181 K ++ + + Y E K E+EE+ VL ++ K+ E++ + SL Sbjct: 1296 KMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENL 1355 Query: 182 TL----NIVNLRCETQDILKHASNLTKSSSELKKEVDEME-----------IEINYLNQQ 226 + NI+ L ++ + ++ E K+E +E EI +L+ Sbjct: 1356 EIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAHEIAWLHGT 1415 Query: 227 ISRHNE--------------------------TKALSETLEEKNKNTENRKELKERI--- 257 I H E ++E EK K E ++LKER+ Sbjct: 1416 IQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTIL 1475 Query: 258 --------FGKDEHVL---------TLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI 300 G+ E L T ++ Q L YES+KL + + +E + + Sbjct: 1476 VKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNE--ITTL 1533 Query: 301 KEESSAKQSKLANIDFRQKE 320 EE S KL ++ Q+E Sbjct: 1534 NEEDSISNLKLGTLNGSQEE 1553 >gi|148536871 ninein isoform 1 [Homo sapiens] Length = 2046 Score = 41.6 bits (96), Expect = 0.002 Identities = 61/308 (19%), Positives = 127/308 (41%), Gaps = 55/308 (17%) Query: 59 DEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDY--------MQDQFTVYQGTVEKDKEM 110 ++++ HY K +E +C+ + ++E + ++++ QG KE Sbjct: 630 EDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEA 689 Query: 111 YHDYICQYKEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLAC-----TEQLKMNETI 165 +H+ C+++E KQ Q+K E + + + E+++R+ E+ + + Sbjct: 690 HHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSA 749 Query: 166 FMKFRVPAPFPSLTKW-----TLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEI 220 + + +V L ++ T + E +++ K L K EL++ ++ME E Sbjct: 750 WTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKEL--LEKHQRELQEGREKMETEC 807 Query: 221 NYLNQQISR--HNETKALSETLEEKNKNTENR-----KELKER--------IFGKDEHVL 265 N QI ++ + ++E E ++ E R K+L+E+ F KDE Sbjct: 808 NRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQ 867 Query: 266 -----------TLNKTQSSQLFLPYESQKLVRPIKMHSSEPRV---------ADIKEESS 305 TL + +++ L L E + L + K H + V D++ S Sbjct: 868 ECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSE 927 Query: 306 AKQSKLAN 313 +QS L++ Sbjct: 928 TQQSLLSD 935 Score = 36.6 bits (83), Expect = 0.066 Identities = 66/320 (20%), Positives = 118/320 (36%), Gaps = 68/320 (21%) Query: 67 KHSEEIKDNCRNWKPTCDVFRKHEDYMQDQF----TVYQGTVEKDKEMYHDYICQYKEVL 122 K E I + +K + + D +Q++ T Y +E +KE+ + E+ Sbjct: 1236 KMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELK 1295 Query: 123 KQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQL-KMNETIFMKFRVPAPFPSLTKW 181 K ++ + + Y E K E+EE+ VL ++ K+ E++ + SL Sbjct: 1296 KMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENL 1355 Query: 182 TL----NIVNLRCETQDILKHASNLTKSSSELKKEVDEME-----------IEINYLNQQ 226 + NI+ L ++ + ++ E K+E +E EI +L+ Sbjct: 1356 EIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAHEIAWLHGT 1415 Query: 227 ISRHNE--------------------------TKALSETLEEKNKNTENRKELKERI--- 257 I H E ++E EK K E ++LKER+ Sbjct: 1416 IQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTIL 1475 Query: 258 --------FGKDEHVL---------TLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI 300 G+ E L T ++ Q L YES+KL + + +E + + Sbjct: 1476 VKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNE--ITTL 1533 Query: 301 KEESSAKQSKLANIDFRQKE 320 EE S KL ++ Q+E Sbjct: 1534 NEEDSISNLKLGTLNGSQEE 1553 >gi|148536869 ninein isoform 2 [Homo sapiens] Length = 2133 Score = 41.6 bits (96), Expect = 0.002 Identities = 61/308 (19%), Positives = 127/308 (41%), Gaps = 55/308 (17%) Query: 59 DEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDY--------MQDQFTVYQGTVEKDKEM 110 ++++ HY K +E +C+ + ++E + ++++ QG KE Sbjct: 630 EDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEA 689 Query: 111 YHDYICQYKEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLAC-----TEQLKMNETI 165 +H+ C+++E KQ Q+K E + + + E+++R+ E+ + + Sbjct: 690 HHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSA 749 Query: 166 FMKFRVPAPFPSLTKW-----TLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEI 220 + + +V L ++ T + E +++ K L K EL++ ++ME E Sbjct: 750 WTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKEL--LEKHQRELQEGREKMETEC 807 Query: 221 NYLNQQISR--HNETKALSETLEEKNKNTENR-----KELKER--------IFGKDEHVL 265 N QI ++ + ++E E ++ E R K+L+E+ F KDE Sbjct: 808 NRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQ 867 Query: 266 -----------TLNKTQSSQLFLPYESQKLVRPIKMHSSEPRV---------ADIKEESS 305 TL + +++ L L E + L + K H + V D++ S Sbjct: 868 ECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSE 927 Query: 306 AKQSKLAN 313 +QS L++ Sbjct: 928 TQQSLLSD 935 Score = 36.6 bits (83), Expect = 0.066 Identities = 66/320 (20%), Positives = 118/320 (36%), Gaps = 68/320 (21%) Query: 67 KHSEEIKDNCRNWKPTCDVFRKHEDYMQDQF----TVYQGTVEKDKEMYHDYICQYKEVL 122 K E I + +K + + D +Q++ T Y +E +KE+ + E+ Sbjct: 1236 KMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELK 1295 Query: 123 KQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQL-KMNETIFMKFRVPAPFPSLTKW 181 K ++ + + Y E K E+EE+ VL ++ K+ E++ + SL Sbjct: 1296 KMEEVTETFLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENL 1355 Query: 182 TL----NIVNLRCETQDILKHASNLTKSSSELKKEVDEME-----------IEINYLNQQ 226 + NI+ L ++ + ++ E K+E +E EI +L+ Sbjct: 1356 EIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAHEIAWLHGT 1415 Query: 227 ISRHNE--------------------------TKALSETLEEKNKNTENRKELKERI--- 257 I H E ++E EK K E ++LKER+ Sbjct: 1416 IQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTIL 1475 Query: 258 --------FGKDEHVL---------TLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADI 300 G+ E L T ++ Q L YES+KL + + +E + + Sbjct: 1476 VKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNE--ITTL 1533 Query: 301 KEESSAKQSKLANIDFRQKE 320 EE S KL ++ Q+E Sbjct: 1534 NEEDSISNLKLGTLNGSQEE 1553 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 41.2 bits (95), Expect = 0.003 Identities = 55/270 (20%), Positives = 108/270 (40%), Gaps = 36/270 (13%) Query: 67 KHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLK-QY 125 K +++ N+K T F+ + D Y+ +E+++ M + + KE K Sbjct: 800 KTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDS 859 Query: 126 QLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNI 185 L +T S + E + + E+Q R +NE +K ++ +L Sbjct: 860 SLGALKTELSYKTQELQEKTREVQER---------LNEMEQLKEQLENRDSTLQTVEREK 910 Query: 186 VNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNK 245 + + Q L+ LT+ +LK+ + ++IE + L I + N Sbjct: 911 TLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIH------------DTVNM 958 Query: 246 NTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESS 305 N + +++L+ + +H T+N +S S+++ R + M E + K+E Sbjct: 959 NIDTQEQLRNALESLKQHQETINTLKSK------ISEEVSRNLHM---EENTGETKDEF- 1008 Query: 306 AKQSKLANIDFRQ--KENDTQIFNDSAVDN 333 Q K+ ID +Q + +TQ DN Sbjct: 1009 --QQKMVGIDKKQDLEAKNTQTLTADVKDN 1036 Score = 33.9 bits (76), Expect = 0.43 Identities = 63/375 (16%), Positives = 148/375 (39%), Gaps = 50/375 (13%) Query: 21 EQDISTKEEMIQRINKCCEDIKENKVTI-------CRIHETINATDEEIDHYCKHSEEIK 73 ++++S ++ I I ++K ++T+ + + +N EE+ K + +K Sbjct: 1147 QEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLK 1206 Query: 74 DNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKE---MYHDYICQYKEVLKQYQLKYS 130 + ++ F D+++ + T + KE + H ++ +++E + + + S Sbjct: 1207 ELQKS-------FETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVS 1259 Query: 131 E-TPFSREYYEKKREHEEIQSRVLACTEQLK--------------MNET-IFMKFRVPAP 174 E T + ++ H ++Q + E+ + MNE + + Sbjct: 1260 EKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKD 1319 Query: 175 FPSLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQI----SRH 230 +L + + + L + Q+ + +LTK LK + +E++ + L + I ++ Sbjct: 1320 STTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKI 1379 Query: 231 NETKALSE---TLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRP 287 E+++ E ++EK+ T E+ KD +L + + L L Q Sbjct: 1380 QESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALL---RIEIEMLGLSKRLQ----- 1431 Query: 288 IKMHSSEPRVADIKEESSAKQSKLANIDFRQKENDTQIF-NDSAVDNHSKCSHITTITSS 346 + H VA K++ Q L + + KEN +I + K +H Sbjct: 1432 -ESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQE 1490 Query: 347 QKFMQVRLLTPQKQS 361 + ++R+ +K++ Sbjct: 1491 ETINELRVNLSEKET 1505 >gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] Length = 971 Score = 41.2 bits (95), Expect = 0.003 Identities = 68/373 (18%), Positives = 156/373 (41%), Gaps = 31/373 (8%) Query: 63 DHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVL 122 D H EI++ ++ + K ++ ++ +++ VE +M + + K+++ Sbjct: 69 DLQAAHRREIQELLKSQQDHSASVNKGQEKAEE---LHRMEVESLNKMLEELRLERKKLI 125 Query: 123 KQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWT 182 + Y+ K ++ ++ +YE++ + + A + Q + ++ L K Sbjct: 126 EDYEGKLNK---AQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRK-- 180 Query: 183 LNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQI--SRHNETKALSETL 240 I L+ E Q + A +L +L+ + E + L +Q+ ++ E LS+ Sbjct: 181 -TIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHK 239 Query: 241 EEKNKNTENRKELKER---IFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSE--P 295 E +++ R+ L+++ + K H+ L TQ +Q + ++ ++ S Sbjct: 240 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQ-------EVTIKDLESEKSRVNE 292 Query: 296 RVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRL- 354 R++ ++EE + +SK ++D QK+ QI N +K + K +Q RL Sbjct: 293 RLSQLEEERAFLRSKTQSLDEEQKQ---QILELEKKVNEAKRTQQEYYERELKNLQSRLE 349 Query: 355 --LTPQKQSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGK--SIENDSDE 410 +T +++S E K + +R+ K + +H ++E D ++ Sbjct: 350 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQ 409 Query: 411 VEERAENFPRTSE 423 +++ EN E Sbjct: 410 LQQELENLKEVLE 422 >gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] Length = 1140 Score = 41.2 bits (95), Expect = 0.003 Identities = 68/373 (18%), Positives = 156/373 (41%), Gaps = 31/373 (8%) Query: 63 DHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVL 122 D H EI++ ++ + K ++ ++ +++ VE +M + + K+++ Sbjct: 189 DLQAAHRREIQELLKSQQDHSASVNKGQEKAEE---LHRMEVESLNKMLEELRLERKKLI 245 Query: 123 KQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWT 182 + Y+ K ++ ++ +YE++ + + A + Q + ++ L K Sbjct: 246 EDYEGKLNK---AQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRK-- 300 Query: 183 LNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQI--SRHNETKALSETL 240 I L+ E Q + A +L +L+ + E + L +Q+ ++ E LS+ Sbjct: 301 -TIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHK 359 Query: 241 EEKNKNTENRKELKER---IFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSE--P 295 E +++ R+ L+++ + K H+ L TQ +Q + ++ ++ S Sbjct: 360 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQ-------EVTIKDLESEKSRVNE 412 Query: 296 RVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRL- 354 R++ ++EE + +SK ++D QK+ QI N +K + K +Q RL Sbjct: 413 RLSQLEEERAFLRSKTQSLDEEQKQ---QILELEKKVNEAKRTQQEYYERELKNLQSRLE 469 Query: 355 --LTPQKQSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGK--SIENDSDE 410 +T +++S E K + +R+ K + +H ++E D ++ Sbjct: 470 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQ 529 Query: 411 VEERAENFPRTSE 423 +++ EN E Sbjct: 530 LQQELENLKEVLE 542 >gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens] Length = 1116 Score = 40.0 bits (92), Expect = 0.006 Identities = 63/295 (21%), Positives = 120/295 (40%), Gaps = 41/295 (13%) Query: 120 EVLKQYQLKYSE----TPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPF 175 E+ K+ L+ E T + +Y + E++ +Q + A ++L++ + F+ + Sbjct: 193 ELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSS 252 Query: 176 ----PSLTKWTL-NIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRH 230 P + + T N L E + K L+K ++EME+ I Q ++ Sbjct: 253 RTGEPCVAELTEENFQRLHAEHE-------RQAKELFLLRKTLEEMELRIETQKQTLNAR 305 Query: 231 NET-KALSETLEEKN---KNTENRKELKERIFGKDEHV------LTLNKTQSSQLFLPYE 280 +E+ K L E L+ K K TE E R+ + HV L + ++S L Sbjct: 306 DESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML----- 360 Query: 281 SQKLVRPIKMHSSEPRVADIKEESSAKQSKLANID--FRQKENDTQIFND----SAVDNH 334 +++ R + + ++ K SK+++++ R E + Q+ S + Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420 Query: 335 SKCSHITTITSSQKFM--QVRLLTPQKQSNSNQWSEKGDKDAEYGDKGTVRQVRE 387 + + S KFM +V L + S QW E K A G + + QV++ Sbjct: 421 EEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAA--GLQAEIGQVKQ 473 Score = 37.4 bits (85), Expect = 0.039 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 13/141 (9%) Query: 200 SNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKELKERIFG 259 +N K EL +++++ E+ + ++S ++ A ET N E RK L+E + Sbjct: 868 TNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKET-HLTNLRAERRKHLEEVLEM 926 Query: 260 KDEHVLT-LNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLANIDFRQ 318 K E +L +++ ++ L S K ++ VA +K E +L +Q Sbjct: 927 KQEALLAAISEKDANIALLELSSSK-------KKTQEEVAALKREKDRLVQQLK----QQ 975 Query: 319 KENDTQIFNDSAVDNHSKCSH 339 +N ++ D+ D+H K SH Sbjct: 976 TQNRMKLMADNYEDDHFKSSH 996 Score = 33.5 bits (75), Expect = 0.56 Identities = 28/132 (21%), Positives = 62/132 (46%), Gaps = 10/132 (7%) Query: 188 LRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHN-ETKALSETLEEKNKN 246 ++ + + + + S+ ELKK+ ++ EI + Q++SR + E AL LE Sbjct: 436 MKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQ 495 Query: 247 TENRKE----LKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKE 302 + K+ LKE + K++ L +T+ L L E ++ + ++ ++ D+ E Sbjct: 496 FSDSKQHIEVLKESLTAKEQRAAIL-QTEVDALRLRLEEKETM----LNKKTKQIQDMAE 550 Query: 303 ESSAKQSKLANI 314 E + ++ ++ Sbjct: 551 EKGTQAGEIHDL 562 Score = 31.2 bits (69), Expect = 2.8 Identities = 56/302 (18%), Positives = 118/302 (39%), Gaps = 56/302 (18%) Query: 24 ISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWKPTC 83 I K+ I + + D++E ++ + + + ++ + E EE+K Sbjct: 384 IEMKDSKISSMERGLRDLEE-EIQMLKSNGALSTEERE--------EEMKQ--------M 426 Query: 84 DVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEKKR 143 +V+R H +M+++ VE+ KE Q++E LK E + K+ Sbjct: 427 EVYRSHSKFMKNK-------VEQLKEELSSKEAQWEE------LKKKAAGLQAEIGQVKQ 473 Query: 144 EHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHASNLT 203 E + +LA +L ET+ +F + K +L R Sbjct: 474 ELSRKDTELLALQTKL---ETLTNQFSDSKQHIEVLKESLTAKEQR-------------- 516 Query: 204 KSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKELKERIFGKDEH 263 ++ L+ EVD + + + +++ +TK + + EEK +LK+ + K+ Sbjct: 517 --AAILQTEVDALRLRLEEKETMLNK--KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERK 572 Query: 264 VLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLANIDFRQKENDT 323 V L K + + Q + +M S + RV ++ +++ + L ++ E + Sbjct: 573 VNVLQKKIEN-----LQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 627 Query: 324 QI 325 I Sbjct: 628 TI 629 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 40.0 bits (92), Expect = 0.006 Identities = 56/304 (18%), Positives = 117/304 (38%), Gaps = 27/304 (8%) Query: 126 QLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNI 185 +L S E Y EE++ + E+L++ E+ K + L K L Sbjct: 185 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES--EKSEIQLNVKEL-KRKLER 241 Query: 186 VNLRCETQDILKHASNLTKS----SSELKKEVDEMEIEINYLNQQISRH--NETKALSET 239 L Q + A +L K S++L+ +V+E E+ N LNQQ + + + E Sbjct: 242 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQER 300 Query: 240 LEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVAD 299 E+ + E +E +E++ ++E + + Q + +E ++ +R ++ E Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360 Query: 300 IKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQK 359 +EE ++ K+ + RQ++ + + Q + Q+ Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-----------------QEEKIREQE 403 Query: 360 QSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAENFP 419 + Q + G+++ + ++ Q +E K Q K I +++ E+ E Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463 Query: 420 RTSE 423 E Sbjct: 464 EQEE 467 Score = 32.0 bits (71), Expect = 1.6 Identities = 56/304 (18%), Positives = 127/304 (41%), Gaps = 27/304 (8%) Query: 12 LLLEFVFQYEQDISTKEEMIQRIN-KCCEDIKENKVTICRIHETINATDEEIDHYCKHSE 70 LL + Q E D KE +Q ++ K ++EN+ + +N EE + E Sbjct: 245 LLPQQQLQAEADHLGKE--LQSVSAKLQAQVEENE-----LWNRLNQQQEE--KMWRQEE 295 Query: 71 EIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYS 130 +I++ + + R+ E+ M+ Q + EK + + + + +E +++ + K Sbjct: 296 KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKIRELEEKMH 354 Query: 131 ETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRC 190 E RE EK++E E+I+ EQ K E +R + +R Sbjct: 355 EQEKIREQEEKRQEEEKIR-------EQEKRQEQEAKMWRQEEKIREQEE------KIRE 401 Query: 191 ETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENR 250 + + + + + + ++ ++ +EM+ + + +Q + E + EEK + E Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461 Query: 251 KELKERIFGKDEHVLTLN--KTQSSQLFLPYESQKL-VRPIKMHSSEPRVADIKEESSAK 307 + +E G+ E + K Q + + + +K+ + K+ E ++ + +E + Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521 Query: 308 QSKL 311 + K+ Sbjct: 522 EEKM 525 >gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] Length = 1233 Score = 40.0 bits (92), Expect = 0.006 Identities = 72/330 (21%), Positives = 135/330 (40%), Gaps = 51/330 (15%) Query: 97 FTVYQGTVE-------KDKEMYHDYICQYKEVLKQYQLKYSE-------TPFS------- 135 F V+QG VE K++ + I + E+ ++Y + E T F+ Sbjct: 133 FLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNI 192 Query: 136 -REYYEKKREHEE------IQSRVLACTEQLKM-----NETIFMKFR--VPAPFPSLTKW 181 E E K+E EE ++ V+ QL++ NE K + + + K Sbjct: 193 AAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKD 252 Query: 182 TLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLN-QQISRHNETKALSETL 240 + + E ++ K + + +++KE+ E + E+N Q I T + L Sbjct: 253 KKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKL 312 Query: 241 EEKNKNTEN-RKELKERIFGKDE---HVLTLNKT-QSSQLFLPYESQKLVRPIKMHSSE- 294 E K+ +N +K K+R DE +L++ K Q + + ESQ R + + ++ Sbjct: 313 EAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQV 372 Query: 295 PRVADIKEESSAKQSKLA------NIDFRQKENDTQIFNDSAVDNHSKCSH-ITTITSSQ 347 + +KEE+S + + LA N D + ++ + V+ +K + I +Q Sbjct: 373 KKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQ 432 Query: 348 KFMQ--VRLLTPQKQSNSNQWSEKGDKDAE 375 K ++ +T KQS Q +G+ E Sbjct: 433 KRIEKLEEYITTSKQSLEEQKKLEGELTEE 462 Score = 33.5 bits (75), Expect = 0.56 Identities = 58/298 (19%), Positives = 128/298 (42%), Gaps = 48/298 (16%) Query: 44 NKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGT 103 N+V I ++++ + + ++EI+ K ++++D + Sbjct: 231 NEVEIEKLNKELASKNKEIEKDKKRMDKVEDELK-------------------------- 264 Query: 104 VEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNE 163 EK KE+ + + +++ K+ + K SE R Y K +E+ + + L ++ N Sbjct: 265 -EKKKEL-GKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNA 322 Query: 164 TIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHAS-----NLTKSSSELKKE---VDE 215 K R L K L++ R E ++ ++ S +LT +++KK +E Sbjct: 323 QKHYKKR-KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEE 381 Query: 216 MEIEINYLNQQISRHN-ETKALSETLE-EKNKNTENRKELKERIFGKDEHVLTLNK---- 269 L Q++ + N + KA + L+ E+ K E ++K+++ +E+ + K Sbjct: 382 ASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEY 441 Query: 270 -TQSSQLFLPYESQKLVRPI--KMHSSEPRVADIKEESSAKQSKLANIDFRQKENDTQ 324 T S Q E +KL + ++ ++ R+ +I +E + +L + ++E+ Q Sbjct: 442 ITTSKQSL--EEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQ 497 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 40.0 bits (92), Expect = 0.006 Identities = 60/266 (22%), Positives = 119/266 (44%), Gaps = 43/266 (16%) Query: 88 KHEDYMQDQFTVYQ--GTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEKK--- 142 KH +M+ F + + E +KEM KE ++ + + ++T R+ E+K Sbjct: 829 KHWPWMKLYFKIKPLLKSAETEKEM-----ANMKEEFEKTKEELAKTEAKRKELEEKMVT 883 Query: 143 --REHEEIQSRVLACTEQL-----KMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDI 195 +E ++Q +V A + L + ++ I K ++ A +T+ + + E + Sbjct: 884 LMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAE---L 940 Query: 196 LKHASNLTKSSSELKKEVDEMEIEINYL-NQQISRHNETKALSETL----EEKNKNTENR 250 L SELKK++D++E+ + + ++ + N+ K L+E + E K T+ + Sbjct: 941 TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK 1000 Query: 251 KELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSK 310 K L+E H TL+ Q+ + + + K+ E +V D+ E S +Q K Sbjct: 1001 KALQE------AHQQTLDDLQAEE-----DKVNTLTKAKI-KLEQQVDDL--EGSLEQEK 1046 Query: 311 LANIDF----RQKENDTQIFNDSAVD 332 +D R+ E D ++ +S +D Sbjct: 1047 KIRMDLERAKRKLEGDLKLAQESTMD 1072 Score = 35.0 bits (79), Expect = 0.19 Identities = 73/389 (18%), Positives = 159/389 (40%), Gaps = 55/389 (14%) Query: 23 DISTKEEMIQRINKC-------CEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDN 75 D+ +E+ + + K +D++ + +I + +++ K ++E + Sbjct: 1013 DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMD 1072 Query: 76 CRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEV---LKQYQLKYSET 132 N K D K +++ + + Q +E ++ + + KE+ +++ + + Sbjct: 1073 IENDKQQLDEKLKKKEF---EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAE 1129 Query: 133 PFSREYYEKKR-----EHEEIQSRVL----ACTEQLKMN---ETIFMKFRVPAPFPSLTK 180 SR EK+R E EEI R+ A + Q++MN E F K R +L + Sbjct: 1130 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL-Q 1188 Query: 181 WTLNIVNLRCETQDIL----KHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKA- 235 LR + D + + NL + +L+KE EM++EI+ L + ++ K Sbjct: 1189 HEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGN 1248 Query: 236 ---LSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHS 292 + LE++ + ++E ++R+ +N + + L ES + R + Sbjct: 1249 LEKMCRALEDQLSEIKTKEEEQQRL---------INDLTAQRARLQTESGEYSRQL---- 1295 Query: 293 SEPRVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAV-----DNHSKCSHITTITSSQ 347 + + + + S KQ+ I+ +++ + +I SA+ + C + + Sbjct: 1296 -DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEE 1354 Query: 348 KFMQVRLLTPQKQSNSN--QWSEKGDKDA 374 + + L ++NS QW K + DA Sbjct: 1355 QEAKAELQRAMSKANSEVAQWRTKYETDA 1383 Score = 32.7 bits (73), Expect = 0.95 Identities = 55/316 (17%), Positives = 127/316 (40%), Gaps = 34/316 (10%) Query: 31 IQRINKCCEDIKENKVTICRI-----------HETINATDEEIDHYCKHSEEIKDNCRNW 79 ++R N C + + + +I H + A+ +E +IK+ Sbjct: 1436 VERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEES 1495 Query: 80 KPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYY 139 + ++ +Q + + + + + H+ +++ KQ + + SE + E Sbjct: 1496 LDQLETLKRENKNLQQEISDLTEQIAEGGKRIHEL----EKIKKQVEQEKSELQAALEEA 1551 Query: 140 EKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAP----FPSLTKWTLNIVNLRCETQDI 195 E EHEE ++L QL++N+ R A + + + IV T D Sbjct: 1552 EASLEHEE--GKILRI--QLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDA 1607 Query: 196 -LKHASNLTKSSSELKKEVDEMEIEINYLNQQISR-----HNETKALSETLEEKNKNTEN 249 ++ ++ + +++ +++EMEI++N+ N+ + N L +T + + Sbjct: 1608 EIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRS 1667 Query: 250 RKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQS 309 +++LKE++ E L + + +L E + R I +E + D E + Sbjct: 1668 QEDLKEQL-AMVERRANLLQAEIEELRATLEQTERSRKI----AEQELLDASERVQLLHT 1722 Query: 310 KLANIDFRQKENDTQI 325 + ++ +K+ +T I Sbjct: 1723 QNTSLINTKKKLETDI 1738 >gi|110815815 centlein isoform 1 [Homo sapiens] Length = 1406 Score = 39.7 bits (91), Expect = 0.008 Identities = 52/256 (20%), Positives = 106/256 (41%), Gaps = 33/256 (12%) Query: 119 KEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSL 178 KE+L+Q K +E + +EK+ SR L + M E F+K SL Sbjct: 684 KEMLEQTLQKVTELENRLKSFEKR-------SRKLKEGNKKLMKENDFLK--------SL 728 Query: 179 TKWTLNIVNLR-CETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALS 237 K R E + I+K + ++ K ++EL+ ++ E+E E+ L +Q++ N Sbjct: 729 LKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEAN------ 782 Query: 238 ETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRV 297 L +N+ N E + + + + K +S + Y+ + + +K +++ Sbjct: 783 -ALRNENEELINPMEKSHQSADRAKSEMATMKVRSGR----YDCKTTMTKVKFKAAK--- 834 Query: 298 ADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTP 357 K S + + N + N + + ++ S+ S + +SQ + + T Sbjct: 835 ---KNCSVGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLGTIIVETS 891 Query: 358 QKQSNSNQWSEKGDKD 373 QK S + ++ + D Sbjct: 892 QKISPTEDGKDQKESD 907 Score = 35.4 bits (80), Expect = 0.15 Identities = 36/146 (24%), Positives = 61/146 (41%), Gaps = 12/146 (8%) Query: 123 KQYQLKYSETPFSREYYEKKREH-EEIQSRVLACTEQLKMNE-----TIFMKFRVPAPFP 176 K QLK E R+ +EK++E + +Q+ A EQLK E T K + P Sbjct: 543 KALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQ 602 Query: 177 -----SLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHN 231 S W + + E Q+++ NL + ELK + + I LN+ ++ Sbjct: 603 LRQEDSDAVWN-ELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERR 661 Query: 232 ETKALSETLEEKNKNTENRKELKERI 257 E + +++ K + K KE + Sbjct: 662 EEQLFRSGEDDEVKRSTPEKNGKEML 687 Score = 34.3 bits (77), Expect = 0.33 Identities = 29/140 (20%), Positives = 66/140 (47%), Gaps = 7/140 (5%) Query: 188 LRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNT 247 L+ E D++K + + ++ L+KE ++E + +Q+I +TK + EE+N+ Sbjct: 183 LKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEI---KDTKECVQNKEEQNRLV 239 Query: 248 -ENRKELKERIFGKDEHVLT-LNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESS 305 +N +E +++ + +L L K + + L +K K+ + E + + ++E Sbjct: 240 IKNLEEENKKLSTRCTDLLNDLEKLRKQEAHL--RKEKYSTDAKIKTFEDNLIEARKEVE 297 Query: 306 AKQSKLANIDFRQKENDTQI 325 QSK + + T++ Sbjct: 298 VSQSKYNALSLQLSNKQTEL 317 Score = 32.7 bits (73), Expect = 0.95 Identities = 37/181 (20%), Positives = 77/181 (42%), Gaps = 19/181 (10%) Query: 122 LKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLK--------MNETIFMKFRVPA 173 L+ QL+Y + E ++ + ++ +LA E +K M I MK + Sbjct: 1092 LEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIE 1151 Query: 174 PFPSLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNET 233 K VNL + + NL K L +E ++ I+ L Q+++ + Sbjct: 1152 DLKFRQK-----VNLE-SNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKE 1205 Query: 234 KALSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSS 293 K+ E + +K+K +K+LK + V +++T+S+ + + K ++ + + S Sbjct: 1206 KSQYEQMYQKSKEELEKKDLKLTLL-----VSRISETESAMAEIETAASKQLQELALQSE 1260 Query: 294 E 294 + Sbjct: 1261 Q 1261 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.363 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,288,652 Number of Sequences: 37866 Number of extensions: 1051144 Number of successful extensions: 3872 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 305 Number of HSP's that attempted gapping in prelim test: 3467 Number of HSP's gapped (non-prelim): 708 length of query: 587 length of database: 18,247,518 effective HSP length: 108 effective length of query: 479 effective length of database: 14,157,990 effective search space: 6781677210 effective search space used: 6781677210 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.